BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo sapiens] (1690 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo s... 3509 0.0 gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo ... 3478 0.0 gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] 1169 0.0 gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 882 0.0 gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 756 0.0 gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo s... 538 e-152 gi|57864582 hornerin [Homo sapiens] 101 7e-21 gi|62122917 filaggrin family member 2 [Homo sapiens] 84 9e-16 gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 77 1e-13 gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 68 7e-11 gi|161016767 mucin 21 [Homo sapiens] 68 7e-11 gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 67 1e-10 gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 65 6e-10 gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 60 2e-08 gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 60 2e-08 gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 60 2e-08 gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 60 2e-08 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 59 4e-08 gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 56 3e-07 gi|148833508 notch1 preproprotein [Homo sapiens] 55 6e-07 gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] 54 1e-06 gi|62953127 polyhomeotic 1-like [Homo sapiens] 54 2e-06 gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 53 2e-06 gi|109255251 loricrin [Homo sapiens] 53 3e-06 gi|221139761 zinc finger protein 853 [Homo sapiens] 52 4e-06 gi|33286444 mastermind-like 2 [Homo sapiens] 52 4e-06 gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] 52 4e-06 gi|48762934 alpha 2 type I collagen [Homo sapiens] 52 6e-06 gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 52 6e-06 gi|93141033 PAX interacting protein 1 [Homo sapiens] 51 1e-05 >gi|33413425 trinucleotide repeat containing 6C isoform 2 [Homo sapiens] Length = 1690 Score = 3509 bits (9098), Expect = 0.0 Identities = 1690/1690 (100%), Positives = 1690/1690 (100%) Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120 Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN Sbjct: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180 Query: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS Sbjct: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240 Query: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS Sbjct: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300 Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS Sbjct: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360 Query: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR Sbjct: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420 Query: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG Sbjct: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480 Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600 Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660 Query: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR Sbjct: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720 Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP Sbjct: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780 Query: 781 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 840 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS Sbjct: 781 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 840 Query: 841 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 900 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV Sbjct: 841 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 900 Query: 901 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 960 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA Sbjct: 901 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 960 Query: 961 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1020 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK Sbjct: 961 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1020 Query: 1021 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1080 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG Sbjct: 1021 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1080 Query: 1081 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1140 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT Sbjct: 1081 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1140 Query: 1141 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1200 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ Sbjct: 1141 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1200 Query: 1201 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1260 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN Sbjct: 1201 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1260 Query: 1261 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1320 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP Sbjct: 1261 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1320 Query: 1321 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1380 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG Sbjct: 1321 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1380 Query: 1381 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSD 1440 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSD Sbjct: 1381 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSD 1440 Query: 1441 IKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS 1500 IKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS Sbjct: 1441 IKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSS 1500 Query: 1501 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE 1560 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE Sbjct: 1501 GSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKE 1560 Query: 1561 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG 1620 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG Sbjct: 1561 EAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAG 1620 Query: 1621 SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLL 1680 SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLL Sbjct: 1621 SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLL 1680 Query: 1681 PGDLLSGESL 1690 PGDLLSGESL Sbjct: 1681 PGDLLSGESL 1690 >gi|217416332 trinucleotide repeat containing 6C isoform 1 [Homo sapiens] Length = 1726 Score = 3478 bits (9018), Expect = 0.0 Identities = 1687/1729 (97%), Positives = 1687/1729 (97%), Gaps = 42/1729 (2%) Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS Sbjct: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT Sbjct: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVAT 120 Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN Sbjct: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLN 180 Query: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS Sbjct: 181 TDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240 Query: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS Sbjct: 241 AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDS 300 Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS Sbjct: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360 Query: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR Sbjct: 361 TGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGR 420 Query: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG Sbjct: 421 RRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWG 480 Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS Sbjct: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA Sbjct: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600 Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK Sbjct: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660 Query: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR Sbjct: 661 PGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRR 720 Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP Sbjct: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPP 780 Query: 781 HQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 840 HQAGTQLNRSPLLGP VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS Sbjct: 781 HQAGTQLNRSPLLGP---VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 837 Query: 841 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 900 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV Sbjct: 838 GSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 897 Query: 901 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 960 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA Sbjct: 898 WNNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEA 957 Query: 961 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1020 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK Sbjct: 958 LKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDK 1017 Query: 1021 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1080 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG Sbjct: 1018 DGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFG 1077 Query: 1081 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1140 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT Sbjct: 1078 NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLT 1137 Query: 1141 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1200 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ Sbjct: 1138 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1197 Query: 1201 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1260 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN Sbjct: 1198 QHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPN 1257 Query: 1261 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1320 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP Sbjct: 1258 TFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNP 1317 Query: 1321 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1380 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG Sbjct: 1318 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1377 Query: 1381 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSG----- 1435 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSG Sbjct: 1378 SSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGSSPP 1437 Query: 1436 ----------------------------------GKLSDIKSTWSSGPTSHTQASLSHEL 1461 GKLSDIKSTWSSGPTSHTQASLSHEL Sbjct: 1438 SSQNATLPSSSAWPLSASGYSSSFSSIASAPSVAGKLSDIKSTWSSGPTSHTQASLSHEL 1497 Query: 1462 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL 1521 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL Sbjct: 1498 WKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSSWLVLRNL 1557 Query: 1522 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA 1581 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA Sbjct: 1558 TPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILA 1617 Query: 1582 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK 1641 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK Sbjct: 1618 EFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAAGSSHGLVRSDAGHWNAPCLGGK 1677 Query: 1642 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1690 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL Sbjct: 1678 GSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGESL 1726 >gi|116805348 trinucleotide repeat containing 6A [Homo sapiens] Length = 1962 Score = 1169 bits (3025), Expect = 0.0 Identities = 775/1813 (42%), Positives = 987/1813 (54%), Gaps = 252/1813 (13%) Query: 1 MATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSS 60 MA+G+ G G + + G N +V S SN +GS+ WG + G+ Sbjct: 271 MASGNTGGEKDG-LRNSTGLGSQNKFVVGSSSNNVG--------HGSSTGPWGFSHGAII 321 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQNCWG--ASNSNAGINLN-LNPNANPAAWPVLGHEGT 117 SV + K ++ N WG +S+SN G+N + LN +N AWPVL + G Sbjct: 322 STCQVSVDAPESKSES---SNNRMNAWGTVSSSSNGGLNPSTLNSASNHGAWPVLENNGL 378 Query: 118 VATGNPSSICSPV----SAIGQNMGNQNGNPT----GTLGAWGNLLPQESTEPQTSTSQN 169 G S S + S IGQ NQ+ N T G WG+L QE+ E + S +Q Sbjct: 379 ALKGPVGSGSSGINIQCSTIGQMPNNQSINSKVSGGSTHGTWGSL--QETCESEVSGTQK 436 Query: 170 VSFSAQPQNLNTD--GPNNT-NPMNSSPNPINAMQTNGLPNWGM-AVGMGAIIPPHLQGL 225 VSFS QPQN+ T+ GPNNT N M SS ++Q N LP+ A + + P +Q Sbjct: 437 VSFSGQPQNITTEMTGPNNTTNFMTSSLPNSGSVQNNELPSSNTGAWRVSTMNHPQMQAP 496 Query: 226 PGANGSSVSQVSGGSAE--GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ-N 282 G NG+S+S +S G ++ G + WG N + + Q NGDTVN+ L N Sbjct: 497 SGMNGTSLSHLSNGESKSGGSYGTTWGAYGSNYSGDKCSGPNGQANGDTVNATLMQPGVN 556 Query: 283 G--SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340 G ++ GG W+SG A +WG G+G N G+ WG P+++T + Sbjct: 557 GPMGTNFQVNTNKGGGVWESGA-ANSQSTSWGSGNGANSGGSRRG--WGTPAQNTGTNLP 613 Query: 341 G-EWGK-PPNQHSNSDINGKGST---GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395 EW K P NQHSN NG G T GW+S Q E + WAK + GT Sbjct: 614 SVEWNKLPSNQHSNDSANGNGKTFTNGWKSTEEEDQGSATSQTNEQSSVWAK--TGGTVE 671 Query: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQ---LPRNDLDPRVLSNTGWGQT 452 S+GS++ +G E +GTGE + RD+ IDQ + + R DLDPRVLSN+GWGQT Sbjct: 672 SDGSTESTGRLEE-----KGTGESQSRDRRKIDQHTLLQSIVNRTDLDPRVLSNSGWGQT 726 Query: 453 PVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNA 512 P+KQNTAW+ E SPR ERK DNGTEAWG +ATQ NSG D + N +TSSVSGW + Sbjct: 727 PIKQNTAWDTETSPRGERKTDNGTEAWGSSATQTFNSGACIDKTSPNGNDTSSVSGWGDP 786 Query: 513 PPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWG 572 PA WGDS K + G W D S A + W N +++ W Sbjct: 787 KPAL-----RWGDS--KGSNCQGGWEDD------SAATGMVKSNQWG---NCKEEKAAWN 830 Query: 573 EPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWND 632 + K K Q WGDGQ+S+ WS D +S H G+ K S +DS+RS SGWN+ Sbjct: 831 DSQKNK-QGWGDGQKSSQGWSVSASDNWGETSRNNHWGEANKKSSSGGSDSDRSVSGWNE 889 Query: 633 TTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA---------- 682 ++ + WGN+ N N + W E+ KP P Q W P+ N WG + Sbjct: 890 LGKTSSFTWGNNINP--NNSSGWDESSKPTPSQGWGDPPKSNQSLGWGDSSKPVSSPDWN 947 Query: 683 -------------ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTS 729 A+ K GTGW+GGP+P K+ E TGWEEPSP SIRRKMEIDDGTS Sbjct: 948 KQQDIVGSWGIPPATGKPPGTGWLGGPIPAPAKEE-EPTGWEEPSPESIRRKMEIDDGTS 1006 Query: 730 AWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNR 789 AWGDPS YN K VNMW++N P S + H++ TP A N+ Sbjct: 1007 AWGDPSKYNYKNVNMWNKNVPNGNSRSDQQAQV----------HQLLTP----ASAISNK 1052 Query: 790 SPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPA 849 G SGWGE WGEPS+P+T VDNGT+AWGKP SG WG+ A Sbjct: 1053 EASSG------SGWGE----------PWGEPSTPATTVDNGTSAWGKPIDSGPSWGEPIA 1096 Query: 850 EPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQ---WEDEEG---DVWNN 903 + V AL K KSMQ+GW GD+M L ++ WE+EE +WN+ Sbjct: 1097 AASSTSTWGSSSVGPQALSKSGPKSMQDGWC--GDDMPLPGNRPTGWEEEEDVEIGMWNS 1154 Query: 904 AASQESTSSCSSWGNAPKKGLQKG------------MKTSGKQDEAWIMSRLIKQLTDMG 951 +SQE SS + W KK KG MK KQ+EAWI + +KQ +++ Sbjct: 1155 NSSQELNSSLN-WPPYTKKMSSKGLSGKKRRRERGMMKGGNKQEEAWI-NPFVKQFSNIS 1212 Query: 952 FPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESS 1011 F R+ EE ++SN M+L M L +K++++DK L + D+N K G RP ISKESS Sbjct: 1213 FSRDSPEENVQSNKMDLSGGM--LQDKRMEIDKHSLNIGDYNRTVGKGPGSRPQISKESS 1270 Query: 1012 VDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQI 1071 ++R + DKDG + +E F+ S S+KLP S+SALP+QALG IA GLGMQNLNS RQ Sbjct: 1271 MERNPYFDKDGIVADESQNMQFMSSQSMKLPPSNSALPNQALGSIA-GLGMQNLNSVRQ- 1328 Query: 1072 PSGNLGMFG-NSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVPQ-FLSPQVQAQLLQFAA 1129 +GN MFG + AAQ R MQQPP QPL+SSQP+LRAQVP LSPQV LL++A Sbjct: 1329 -NGNPSMFGVGNTAAQPRGMQQPP---AQPLSSSQPNLRAQVPPPLLSPQVPVSLLKYAP 1384 Query: 1130 KNIGLNPALLTSPINPQHMTMLNQLYQL-QLAY----QRLQIQQQMLQAQRNVSGSMRQQ 1184 N GLNP PQ + MLNQL QL QL+ QRL QQQ Q+QR+V R Q Sbjct: 1385 NNGGLNPLF-----GPQQVAMLNQLSQLNQLSQISQLQRLLAQQQRAQSQRSVPSGNRPQ 1439 Query: 1185 EQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQT 1244 + Q R ++ +QQQ+ Q RQL LLVKQ PP LH A KS +D+ H Sbjct: 1440 QDQQGRPLS-VQQQMMQQSRQLDPNLLVKQQTPPSQQQ--PLHQPAMKSFLDNVMPHTT- 1495 Query: 1245 PGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPN 1304 P+LQ + S N F+ +P+ GLN N+NVN MDM S+K+P QSRL +WT + Sbjct: 1496 ---PELQ--KGPSPINAFSNFPI-GLNSNLNVN-MDMN---SIKEP---QSRLRKWTTVD 1542 Query: 1305 SMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVP 1364 S+ S + L+QN SKHGAI G + + + YD + +S SPASPP ++ Sbjct: 1543 SI----SVNTSLDQNSSKHGAISSGFRLE-------ESPFVPYDFMNSSTSPASPPGSIG 1591 Query: 1365 HSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTI 1424 W RAKS + SS+NWPPEF PG PWKG NIDPE DP VTPGSV +INT + Sbjct: 1592 DGWPRAKSPN----GSSSVNWPPEFRPGEPWKGYPNIDPETDPYVTPGSVINNLSINT-V 1646 Query: 1425 QDVNRYLLKSGGKLSDIKST------WSS----------------------------GPT 1450 ++V+ ++ G S + +T WSS P Sbjct: 1647 REVDHLRDRNSGSSSSLNTTLPSTSAWSSIRASNYNVPLSSTAQSTSARNSDSKLTWSPG 1706 Query: 1451 SHTQASLSHELWKVP---RNSTAPTRPPPGLTNPKPS-STWGASPL----GWTSS---YS 1499 S T SL+HELWKVP +N TAP+RPPPGLT KP STW SPL GW +S Y+ Sbjct: 1707 SVTNTSLAHELWKVPLPPKNITAPSRPPPGLTGQKPPLSTWDNSPLRIGGGWGNSDARYT 1766 Query: 1500 SGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSK 1559 GS+W +SGR ++WLVL+NLTPQIDGSTLRTLC+QHGPLITFHLNL GNA+VRYSSK Sbjct: 1767 PGSSWGESSSGRITNWLVLKNLTPQIDGSTLRTLCMQHGPLITFHLNLPHGNALVRYSSK 1826 Query: 1560 EEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQALPPTSSWQSSSASSQPRLSAA 1619 EE KAQKSLHMCVLGNTTILAEFA EEE++RF AQ Q+L P+ WQ S SSQ RL + Sbjct: 1827 EEVVKAQKSLHMCVLGNTTILAEFASEEEISRFFAQSQSLTPSPGWQ-SLGSSQSRLGSL 1885 Query: 1620 GSSHGL-VRSDAGHWNAPCLGGKGSSEL----LWGGVPQYSSSLWGPPSADDSRVIGSPT 1674 SH R+D HWN L G +L LW G P YS+SLWGPPS+ D R I SP+ Sbjct: 1886 DCSHSFSSRTDLNHWNGAGLSGTNCGDLHGTSLW-GTPHYSTSLWGPPSSSDPRGISSPS 1944 Query: 1675 PLTTLLPGDLLSG 1687 P+ L D L G Sbjct: 1945 PINAFLSVDHLGG 1957 >gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo sapiens] Length = 1833 Score = 882 bits (2280), Expect = 0.0 Identities = 672/1818 (36%), Positives = 868/1818 (47%), Gaps = 337/1818 (18%) Query: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66 T+ ++ N N + S +S L ++ G ++ ++G+ L S Sbjct: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267 Query: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121 V + + G G +N G G N NPN+NP+AWP L EGT G Sbjct: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181 + S+ + VS +GQ Q +S + VS Q Q NT Sbjct: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370 Query: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238 DGP N TN +N SSPNP+ N GM GMG G + + SQ +G Sbjct: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415 Query: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288 G S WG + G T G SNSG + NG D+ A K GS S Sbjct: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474 Query: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346 S G +W+ GP WG G N + G W P+ S + GEW P Sbjct: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530 Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406 PN + + N KG P +Q P W +++SS + G S GS NH Sbjct: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578 Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464 GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE Sbjct: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638 Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524 PR E K+D GTE W AATQ NSGG D S + SGW + A+T W Sbjct: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690 Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584 D P G W D ++ + + W G E +W E P K Q WG Sbjct: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734 Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644 G++ N WS+G W + D KN S W++ +++ SGW + ++ WGN Sbjct: 735 GRQPNQGWSSGKNGWGEEV-------DQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786 Query: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGGA-- 682 N W E K P N + PQ +WGG Sbjct: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845 Query: 683 ---ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739 +V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN Sbjct: 846 PPPGNVRPSNSSWSSGPQPATPKDE-EPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904 Query: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKV 799 K VN+WD+N+ + N T T Sbjct: 905 KNVNLWDKNSQGGPAPREPNLPTPMT---------------------------------- 930 Query: 800 SSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAG 859 SK+ + W + + P+ DNGT+AWG+P S GWG+ G Sbjct: 931 -----------SKSASVWSKSTPPAP--DNGTSAWGEPNESSPGWGEMDDTGASTTGWGN 977 Query: 860 APVAASALCKPASKSMQEGWG-SGGDEMNLSTSQWEDEE-GDVWNNAASQESTSS--CSS 915 P A KP SKSMQ+GWG S G WE+EE G VWN SQ S SS +S Sbjct: 978 TPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGSQGSASSHNSAS 1037 Query: 916 WGNAPKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSAL 975 WG KK ++ +K G +++W M+ L KQ ++MG + + + +D ++ +L Sbjct: 1038 WGQGGKKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTEDNP----SSKMDLSVGSL 1090 Query: 976 LEKKVDVDKRGLGVTDHNGMAAKPL-GCRPPISKE-SSVDRPTFLDK--------DGGLV 1025 +KK DVDKR + + D N + K G RPP SK+ + D + +K DG L Sbjct: 1091 SDKKFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKLTLPFSNQDGCLG 1150 Query: 1026 EEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAA 1085 +E SPF PSPS KL S S LP+ +LG I +GL QN ++RQ G+ G+FGNS A Sbjct: 1151 DEAPCSPFSPSPSYKLSPSGSTLPNVSLGAIGTGLNPQNF-AARQ--GGSHGLFGNS-TA 1206 Query: 1086 QARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLT--SP 1142 Q+R + P VQPLNSS PSLRAQVP QF+SPQV A +L+ N GL+P L Sbjct: 1207 QSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQ 1260 Query: 1143 INPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQRNVSGSMRQQ-EQQVARTITNL 1195 ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ QR +S ++RQQ EQQ+AR ++ L Sbjct: 1261 LSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSAL 1320 Query: 1196 QQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQ 1255 QQQ QQ QRQ P H HP K +D+ + GLPDLQTK Sbjct: 1321 QQQQQQQQRQ-------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG- 1366 Query: 1256 QSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAA 1313 P+ G + MD M GG + ++SR QWT + M+ LPS A Sbjct: 1367 ----------PIPGYGSGFSSGGMDYGMVGGKE----AGTESRFKQWT--SMMEGLPSVA 1410 Query: 1314 SPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSD 1373 + E N K+GAI PGK+ Y ++D+I A SW AKS Sbjct: 1411 TQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIPGDTLGGHTGPA-GDSWLPAKSP 1462 Query: 1374 -SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYL 1431 ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + L Sbjct: 1463 PTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQL 1521 Query: 1432 LK----------------------------------SGGKLSDIKSTWSSGPTSHTQASL 1457 L+ + K D KSTWS P H L Sbjct: 1522 LRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHL 1581 Query: 1458 SHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTD 1507 S+++WK RN+T RPPPGLTNPKPSS W + S GW S +S S WS Sbjct: 1582 SNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDG 1641 Query: 1508 TSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQK 1567 S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ Sbjct: 1642 GSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQT 1701 Query: 1568 SLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------P 1614 +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P P + WQS P Sbjct: 1702 ALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGP 1761 Query: 1615 RLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIG 1671 L+ G S GL G W++ G G + LW G P YSSSLWG P+ +D +G Sbjct: 1762 ALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMG 1815 Query: 1672 SPTPLTTLLPGDLLSGES 1689 SP P LLPGDLL G S Sbjct: 1816 SPAP---LLPGDLLGGGS 1830 Score = 44.3 bits (103), Expect = 0.001 Identities = 95/497 (19%), Positives = 177/497 (35%), Gaps = 83/497 (16%) Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536 C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ + Sbjct: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186 Query: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594 W I W A+++ +S + + + G + + P + Sbjct: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 Query: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649 G G S+S + N W +D +++T N+G GN N Sbjct: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293 Query: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697 NP +N W ++ G + A + ++N S ++V QT Sbjct: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344 Query: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754 +Q+ E G + ++ DG P N N ++N+ N N + Sbjct: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396 Query: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814 T+ +T S +T +T G R P S G N + E Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454 Query: 815 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 861 +SW G ST N G+ +G S+ + WG+ + V+ G P Sbjct: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 920 S ++ G SG ++ N ST W++++G + + + WG ++ Sbjct: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563 Query: 921 KKGLQKGMKTSGKQDEA 937 G + G +++G +A Sbjct: 564 STGSEVGGQSTGSNHKA 580 >gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo sapiens] Length = 1723 Score = 756 bits (1953), Expect = 0.0 Identities = 621/1807 (34%), Positives = 808/1807 (44%), Gaps = 425/1807 (23%) Query: 14 TKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHC-------S 66 T+ ++ N N + S +S L ++ G ++ ++G+ L S Sbjct: 208 TESSSENTTDNNSASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPKAKS 267 Query: 67 VSGGDGKMDTMIGDGRSQNCWGASNSNAGINL-NLNPNANPAAWPVLGHEGTVATG---- 121 V + + G G +N G G N NPN+NP+AWP L EGT G Sbjct: 268 VQSSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALET 327 Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181 + S+ + VS +GQ Q +S + VS Q Q NT Sbjct: 328 DNSNSSAQVSTVGQTSREQ-----------------QSKMENAGVNFVVSGREQAQIHNT 370 Query: 182 DGPNN--TNPMN-SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSG 238 DGP N TN +N SSPNP+ N GM GMG G + + SQ +G Sbjct: 371 DGPKNGNTNSLNLSSPNPME--------NKGMPFGMGL-------GNTSRSTDAPSQSTG 415 Query: 239 GSAEGISNSVWGLSPGNPAT----GNSNSGFSQGNG----DTVNSALSAKQNGSS--SAV 288 G S WG + G T G SNSG + NG D+ A K GS S Sbjct: 416 DRKTGSVGS-WGAARGPSGTDTVSGQSNSGNNGNNGKEREDSWKGASVQKSTGSKNDSWD 474 Query: 289 QKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP-- 346 S G +W+ GP WG G N + G W P+ S + GEW P Sbjct: 475 NNNRSTGGSWNFGPQDSNDN-KWGEG--NKMTSGVSQGEWKQPTGSDELKI-GEWSGPNQ 530 Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406 PN + + N KG P +Q P W +++SS + G S GS NH Sbjct: 531 PNSSTGAWDNQKGH-----PLPENQGNAQAP------CWGRSSSSTGSEVGGQSTGS-NH 578 Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQ--LPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464 GS+ +G R Q +Q L R DLDPRVLSNTGWGQT +KQ+T W+ EE Sbjct: 579 KAGSSDSHNSGRRSYRPTHPDCQAVLQTLLSRTDLDPRVLSNTGWGQTQIKQDTVWDIEE 638 Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524 PR E K+D GTE W AATQ NSGG D S + SGW + A+T W Sbjct: 639 VPRPEGKSDKGTEGWESAATQTKNSGGWGDAP---SQSNQMKSGW-----GELSASTEWK 690 Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584 D P G W D ++ + + W G E +W E P K Q WG Sbjct: 691 D-----PKNTGGWNDYKNNNSSN----------WGGGRPDEKTPSSWNENPS-KDQGWGG 734 Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNS 644 G++ N WS+G W G D KN S W++ +++ SGW + ++ WGN Sbjct: 735 GRQPNQGWSSGKNGW-------GEEVDQTKN-SNWESSASKPVSGWGEGGQNEIGTWGNG 786 Query: 645 TNTKANPGTNWGETLKPGPQQNWASK--------------------PQDNNVSNWGG--- 681 N W E K P N + PQ +WGG Sbjct: 787 GNASLASKGGW-EDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPP 845 Query: 682 --AASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNN 739 +V+ + + W GP P KD E +GWEEPSP SI RKM+IDDGTSAWGDP++YN Sbjct: 846 PPPGNVRPSNSSWSSGPQPATPKD-EEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNY 904 Query: 740 KTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKV 799 K VN+WD+N+ + N T T+ +++ + + + Sbjct: 905 KNVNLWDKNSQGGPAPREPNLPTPMTSKSASDS------------------------KSM 940 Query: 800 SSGWGEMPN-VHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRA 858 GWGE V SW E D G W S GS Sbjct: 941 QDGWGESDGPVTGARHPSWEEEE------DGG--VWNTTGSQGS---------------- 976 Query: 859 GAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGN 918 AS WG GG Sbjct: 977 ------------ASSHNSASWGQGG----------------------------------- 989 Query: 919 APKKGLQKGMKTSGKQDEAWIMSRLIKQLTDMGFPREPAEEALKSNNMNLDQAMSALLEK 978 KK ++ +K G +++W M+ L KQ ++MG + + + + +D ++ +L +K Sbjct: 990 --KKQMKCSLK--GGNNDSW-MNPLAKQFSNMGLLSQTED----NPSSKMDLSVGSLSDK 1040 Query: 979 KVDVDKRGLGVTDHNGMAAKP-LGCRPPISKE-SSVDRPTFLDKDGGLVEEPTPSPFLPS 1036 K DVDKR + + D N + K G RPP SK+ + D + +K G Sbjct: 1041 KFDVDKRAMNLGDFNDIMRKDRSGFRPPNSKDMGTTDSGPYFEKGG-------------- 1086 Query: 1037 PSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQP 1096 SH G+FGNS AQ+R + Sbjct: 1087 -------SH-------------------------------GLFGNS-TAQSRGL----HT 1103 Query: 1097 PVQPLNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT--SPINPQHMTMLNQ 1153 PVQPLNSS PSLRAQV PQF+SPQV A +L+ N GL+P L ++PQ + ML+Q Sbjct: 1104 PVQPLNSS-PSLRAQVPPQFISPQVSASMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQ 1161 Query: 1154 LYQL---QLAYQRL---QIQQQMLQAQRNVSGSMR-QQEQQVARTITNLQQQIQQHQRQL 1206 L Q+ QLA Q L Q QQQ+LQ QR +S ++R QQEQQ+AR ++ LQQQ QQ QRQ Sbjct: 1162 LPQIPQFQLACQLLLQQQQQQQLLQNQRKISQAVRQQQEQQLARMVSALQQQQQQQQRQ- 1220 Query: 1207 AQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYP 1266 P H HP K +D+ + GLPDLQTK P Sbjct: 1221 ------------PGMKHSPSHPVGPKPHLDNMVPNALNVGLPDLQTKG-----------P 1257 Query: 1267 LAGLNPNMNVNSMD--MTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHG 1324 + G + MD M GG + ++SR QWT + M+ LPS A+ E N K+G Sbjct: 1258 IPGYGSGFSSGGMDYGMVGG----KEAGTESRFKQWT--SMMEGLPSVATQ-EANMHKNG 1310 Query: 1325 AIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKS-DSDKI-SNGSS 1382 AI PGK+ Y ++D+I ++ SW AKS ++KI S S+ Sbjct: 1311 AIVA------PGKTRGGSPYNQFDIIP-GDTLGGHTGPAGDSWLPAKSPPTNKIGSKSSN 1363 Query: 1383 INWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLK--------- 1433 +WPPEF PGVPWKG+QNIDPE+DP VTPGSV G T + I D + LL+ Sbjct: 1364 ASWPPEFQPGVPWKGIQNIDPESDPYVTPGSV-LGGTATSPIVDTDHQLLRDNTTGSNSS 1422 Query: 1434 -------------------------SGGKLSDIKSTWSSGPTSHTQASLSHELWK---VP 1465 + K D KSTWS P H LS+++WK Sbjct: 1423 LNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISS 1482 Query: 1466 RNSTAPTRPPPGLTNPKPSSTWGA----SPLGW---TSSYSSGSAWSTDTSGRTSSWLVL 1518 RN+T RPPPGLTNPKPSS W + S GW S +S S WS S R S WLVL Sbjct: 1483 RNTTPLPRPPPGLTNPKPSSPWSSTAPRSVRGWGTQDSRLASASTWSDGGSVRPSYWLVL 1542 Query: 1519 RNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTT 1578 NLTPQIDGSTLRT+C+QHGPL+TFHLNLTQG A++RYS+K+EAAKAQ +LHMCVLGNTT Sbjct: 1543 HNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTALIRYSTKQEAAKAQTALHMCVLGNTT 1602 Query: 1579 ILAEFAGEEEVNRFLAQGQ-----ALP--PTSSWQSSSASSQ------PRLSAAGSSHGL 1625 ILAEFA ++EV+RFLAQ Q A P P + WQS P L+ G S GL Sbjct: 1603 ILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSLETGQNQSDPVGPALNLFGGSTGL 1662 Query: 1626 VRSDAGHWNAPCLGGKG---SSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPG 1682 G W++ G G + LW G P YSSSLWG P+ +D +GSP P LLPG Sbjct: 1663 -----GQWSSSAGGSSGADLAGASLW-GPPNYSSSLWGVPTVEDPHRMGSPAP---LLPG 1713 Query: 1683 DLLSGES 1689 DLL G S Sbjct: 1714 DLLGGGS 1720 Score = 44.3 bits (103), Expect = 0.001 Identities = 95/497 (19%), Positives = 177/497 (35%), Gaps = 83/497 (16%) Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG----DSNNKAPSGPGV 536 C A A+ + + G+++ S + ++ + A+ AN+ WG +N +P+ + Sbjct: 127 CTAPGANPNNAQVTGALLQSESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHI 186 Query: 537 WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA-- 594 W I W A+++ +S + + + G + + P + Sbjct: 187 WDKVI--------VDGSDMEEWPCIASKDTESSSENTTDNNSASNPGSEKSTLPGSTTSN 238 Query: 595 -GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKA---- 649 G G S+S + N W +D +++T N+G GN N Sbjct: 239 KGKGSQCQSAS-----SGNECNLGVWKSDPKAKSVQSSNSTTENNNGLGNWRNVSGQDRI 293 Query: 650 ---------NPGTN---WGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPV 697 NP +N W ++ G + A + ++N S ++V QT Sbjct: 294 GPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDNSNSS--AQVSTVGQTSR------- 344 Query: 698 PVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN---NPVIQS 754 +Q+ E G + ++ DG P N N ++N+ N N + Sbjct: 345 --EQQSKMENAGVNFVVSGREQAQIHNTDG------PKNGNTNSLNLSSPNPMENKGMPF 396 Query: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814 T+ +T S +T +T G R P S G N + E Sbjct: 397 GMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAA--RGPSGTDTVSGQSNSGNNGNNGKERE 454 Query: 815 NSW-GEPSSPSTLVDN-----------GTAAWGKPPSSGSGWGD-HPAEPPVAFGRAGAP 861 +SW G ST N G+ +G S+ + WG+ + V+ G P Sbjct: 455 DSWKGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQP 514 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG-NAP 920 S ++ G SG ++ N ST W++++G + + + WG ++ Sbjct: 515 T--------GSDELKIGEWSGPNQPNSSTGAWDNQKG---HPLPENQGNAQAPCWGRSSS 563 Query: 921 KKGLQKGMKTSGKQDEA 937 G + G +++G +A Sbjct: 564 STGSEVGGQSTGSNHKA 580 Score = 32.7 bits (73), Expect = 3.1 Identities = 64/273 (23%), Positives = 90/273 (32%), Gaps = 43/273 (15%) Query: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687 ++ T N W N S NT P G T P P W+S +V WG S Sbjct: 1466 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 1523 Query: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736 + + W GG V Q D S P + + + GT+ Sbjct: 1524 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 1579 Query: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787 Y+ K ++M N I + T+ + + TP AG Q Sbjct: 1580 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 1639 Query: 788 ----NRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVD-NGTAAWGKPPSSGS 842 N+S +GP + G S W + S+ D G + WG P S S Sbjct: 1640 ETGQNQSDPVGPALNLFGG--------STGLGQWSSSAGGSSGADLAGASLWGPPNYSSS 1691 Query: 843 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSM 875 WG E P G + AP+ L S S+ Sbjct: 1692 LWGVPTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1723 >gi|67782330 trinucleotide repeat containing 6B isoform 3 [Homo sapiens] Length = 1029 Score = 538 bits (1386), Expect = e-152 Identities = 398/1000 (39%), Positives = 506/1000 (50%), Gaps = 200/1000 (20%) Query: 774 RVETPPPH--QAGTQLNRSPLLGPGRKVSSGW--GEMPNVHSKTENSWGEPSSPSTLVDN 829 R + PPP G P PG ++ G + S T W + + P+ DN Sbjct: 143 RGQPPPPSCMLLGGGAGPPPCTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAP--DN 200 Query: 830 GTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWG-SGGDEMNL 888 GT+AWG+P S GWG+ G P A KP SKSMQ+GWG S G Sbjct: 201 GTSAWGEPNESSPGWGEMDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGA 260 Query: 889 STSQWEDEE-GDVWNNAASQESTSS--CSSWGNAPKKGLQKGMKTSGKQDEAWIMSRLIK 945 WE+EE G VWN SQ S SS +SWG KK ++ +K G +++W M+ L K Sbjct: 261 RHPSWEEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK--GGNNDSW-MNPLAK 317 Query: 946 QLTDMGFPREPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPL-GCRP 1004 Q ++MG + + + +D ++ +L +KK DVDKR + + D N + K G RP Sbjct: 318 QFSNMGLLSQTEDNP----SSKMDLSVGSLSDKKFDVDKRAMNLGDFNDIMRKDRSGFRP 373 Query: 1005 PISKE-SSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQ 1063 P SK+ + D + +K Sbjct: 374 PNSKDMGTTDSGPYFEK------------------------------------------- 390 Query: 1064 NLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQA 1122 G+ G+FGNS AQ+R + P VQPLNSS PSLRAQVP QF+SPQV A Sbjct: 391 ---------GGSHGLFGNS-TAQSRGLHTP----VQPLNSS-PSLRAQVPPQFISPQVSA 435 Query: 1123 QLLQFAAKNIGLNPALLT--SPINPQHMTMLNQLYQL---QLAYQRL---QIQQQMLQAQ 1174 +L+ N GL+P L ++PQ + ML+QL Q+ QLA Q L Q QQQ+LQ Q Sbjct: 436 SMLK-QFPNSGLSPGLFNVGPQLSPQQIAMLSQLPQIPQFQLACQLLLQQQQQQQLLQNQ 494 Query: 1175 RNVSGSMRQQ-EQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKS 1233 R +S ++RQQ EQQ+AR ++ LQQQ QQ QRQ P H HP K Sbjct: 495 RKISQAVRQQQEQQLARMVSALQQQQQQQQRQ-------------PGMKHSPSHPVGPKP 541 Query: 1234 AMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMD--MTGGLSVKDPS 1291 +D+ + GLPDLQTK P+ G + MD M GG + Sbjct: 542 HLDNMVPNALNVGLPDLQTKG-----------PIPGYGSGFSSGGMDYGMVGGKE----A 586 Query: 1292 QSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQ 1351 ++SR QWT + M+ LPS A+ E N K+GAI PGK+ Y ++D+I Sbjct: 587 GTESRFKQWT--SMMEGLPSVATQ-EANMHKNGAIVA------PGKTRGGSPYNQFDIIP 637 Query: 1352 NSESPASPPVAVPHSWSRAKSD-SDKI-SNGSSINWPPEFHPGVPWKGLQNIDPENDPDV 1409 A SW AKS ++KI S S+ +WPPEF PGVPWKG+QNIDPE+DP V Sbjct: 638 GDTLGGHTGPA-GDSWLPAKSPPTNKIGSKSSNASWPPEFQPGVPWKGIQNIDPESDPYV 696 Query: 1410 TPGSVPTGPTINTTIQDVNRYLLK----------------------------------SG 1435 TPGSV G T + I D + LL+ + Sbjct: 697 TPGSV-LGGTATSPIVDTDHQLLRDNTTGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTS 755 Query: 1436 GKLSDIKSTWSSGPTSHTQASLSHELWK---VPRNSTAPTRPPPGLTNPKPSSTWGA--- 1489 K D KSTWS P H LS+++WK RN+T RPPPGLTNPKPSS W + Sbjct: 756 AKFPDYKSTWSPDPIGHNPTHLSNKMWKNHISSRNTTPLPRPPPGLTNPKPSSPWSSTAP 815 Query: 1490 -SPLGW---TSSYSSGSAWSTDTSGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHL 1545 S GW S +S S WS S R S WLVL NLTPQIDGSTLRT+C+QHGPL+TFHL Sbjct: 816 RSVRGWGTQDSRLASASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHL 875 Query: 1546 NLTQGNAVVRYSSKEEAAKAQKSLHMCVLGNTTILAEFAGEEEVNRFLAQGQ-----ALP 1600 NLTQG A++RYS+K+EAAKAQ +LHMCVLGNTTILAEFA ++EV+RFLAQ Q A P Sbjct: 876 NLTQGTALIRYSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATP 935 Query: 1601 --PTSSWQSSSASSQ------PRLSAAGSSHGLVRSDAGHWNAPCLGGKG---SSELLWG 1649 P + WQS P L+ G S GL G W++ G G + LW Sbjct: 936 SAPAAGWQSLETGQNQSDPVGPALNLFGGSTGL-----GQWSSSAGGSSGADLAGASLW- 989 Query: 1650 GVPQYSSSLWGPPSADDSRVIGSPTPLTTLLPGDLLSGES 1689 G P YSSSLWG P+ +D +GSP P LLPGDLL G S Sbjct: 990 GPPNYSSSLWGVPTVEDPHRMGSPAP---LLPGDLLGGGS 1026 Score = 41.6 bits (96), Expect = 0.007 Identities = 43/200 (21%), Positives = 68/200 (34%), Gaps = 39/200 (19%) Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 C A A+ + + G+++ S + ++ + PPA + WG+ N +P WG+ Sbjct: 163 CTAPGANPNNAQVTGALLQSESGTAPVWSKSTPPAPDNGTSAWGEPNESSPG----WGE- 217 Query: 541 ISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWA 600 + T ST +G N +P P KS G G+ P A W Sbjct: 218 MDDTGAST----------TGWGNTPANAPN-AMKPNSKSMQDGWGESDGPVTGARHPSW- 265 Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLK 660 + G WN T G++ NS + +LK Sbjct: 266 ---------------------EEEEDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLK 304 Query: 661 PGPQQNWASKPQDNNVSNWG 680 G +W + P SN G Sbjct: 305 GGNNDSWMN-PLAKQFSNMG 323 Score = 40.0 bits (92), Expect = 0.019 Identities = 55/219 (25%), Positives = 81/219 (36%), Gaps = 55/219 (25%) Query: 473 DNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP---PAAVPANT-----GWG 524 DNGT AWG ++S G+ D + +S +GW N P P A+ N+ GWG Sbjct: 199 DNGTSAWG-EPNESSPGWGEMDDT------GASTTGWGNTPANAPNAMKPNSKSMQDGWG 251 Query: 525 DSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGD 584 +S+ GP ++ + + G W+ +Q G S WG Sbjct: 252 ESD-----GP------VTGARHPSWEEEEDGGVWNTTGSQ-------GSASSHNSASWGQ 293 Query: 585 GQRSNPAWSAGGGD---W----ADSSSVLGHLGDGKKNGSG-------------WDADSN 624 G + S GG+ W A S +G L + N S +D D Sbjct: 294 GGKKQMKCSLKGGNNDSWMNPLAKQFSNMGLLSQTEDNPSSKMDLSVGSLSDKKFDVDKR 353 Query: 625 RSGSG-WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPG 662 G +ND R SG+ N+K T+ G + G Sbjct: 354 AMNLGDFNDIMRKDRSGF-RPPNSKDMGTTDSGPYFEKG 391 Score = 38.1 bits (87), Expect = 0.073 Identities = 35/157 (22%), Positives = 55/157 (35%), Gaps = 42/157 (26%) Query: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343 + + +Q E W P P +NG + AWG P+ S+ W Sbjct: 176 TGALLQSESGTAPVWSKSTPPAP----------DNG-----TSAWGEPNESSPG-----W 215 Query: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNP------TVQPG---------GEHMNSWAKA 388 G+ D G +TGW + + N ++Q G G SW + Sbjct: 216 GE-------MDDTGASTTGWGNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEE 268 Query: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG 425 G + GS + +HN S G+ G + + KG Sbjct: 269 EDGGVWNTTGSQGSASSHNSASWGQGGKKQMKCSLKG 305 Score = 32.7 bits (73), Expect = 3.1 Identities = 64/273 (23%), Positives = 90/273 (32%), Gaps = 43/273 (15%) Query: 631 NDTTRSGNSGWGN---STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQ 687 ++ T N W N S NT P G T P P W+S +V WG S Sbjct: 772 HNPTHLSNKMWKNHISSRNTTPLPRPPPGLT-NPKPSSPWSSTAP-RSVRGWGTQDSRLA 829 Query: 688 TGTGWI-GGPVP----------VKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSN 736 + + W GG V Q D S P + + + GT+ Sbjct: 830 SASTWSDGGSVRPSYWLVLHNLTPQIDGSTLRTICMQHGPLLTFHLNLTQGTAL----IR 885 Query: 737 YNNK--------TVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQL- 787 Y+ K ++M N I + T+ + + TP AG Q Sbjct: 886 YSTKQEAAKAQTALHMCVLGNTTILAEFATDDEVSRFLAQAQPPTPAATPSAPAAGWQSL 945 Query: 788 ----NRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVD-NGTAAWGKPPSSGS 842 N+S +GP + G S W + S+ D G + WG P S S Sbjct: 946 ETGQNQSDPVGPALNLFGG--------STGLGQWSSSAGGSSGADLAGASLWGPPNYSSS 997 Query: 843 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSM 875 WG E P G + AP+ L S S+ Sbjct: 998 LWGVPTVEDPHRMG-SPAPLLPGDLLGGGSDSI 1029 >gi|57864582 hornerin [Homo sapiens] Length = 2850 Score = 101 bits (251), Expect = 7e-21 Identities = 197/968 (20%), Positives = 327/968 (33%), Gaps = 105/968 (10%) Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62 +GS+ + GH + +G + G S + S G G+ S G SS Sbjct: 1512 SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 1559 Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120 S G G G SQ+ +G S +G + + + P G G+ + Sbjct: 1560 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 1618 Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179 G SS S +G++ G G+ + G + S +S Q+ S S Q Sbjct: 1619 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 1676 Query: 180 NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239 G ++ + + + Q++G G G H GL + SS Q G Sbjct: 1677 ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 1734 Query: 240 SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289 S S +SV+G ++ S G+G + +G SS Sbjct: 1735 SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 1794 Query: 290 KEGSGGNAWDSGPPAGPGIL------AWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343 +EGS S G G G GSG + H GH S +G W Sbjct: 1795 QEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGW 1854 Query: 344 GKPPNQHSNSDINGKG-----STGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEG 398 +H + G S+ W+S T G H +S+ + S +S G Sbjct: 1855 SSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRG 1910 Query: 399 SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PV 454 GS + + S G+ G+G + G G Q P R +G GQ+ P Sbjct: 1911 EQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPY 1967 Query: 455 KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPP 514 + W P E + + + + +SG GS ++T G + Sbjct: 1968 GSGSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQS 2026 Query: 515 AAV---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTW 571 ++ A++G S+ + SG S + + GH G+ +++ SP++ Sbjct: 2027 SSCGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSY 2081 Query: 572 GEPPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSG 627 G + GQ + G +S SS G G + SG+ +RSG Sbjct: 2082 GRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG 2141 Query: 628 SGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASV 685 +SG S++ G+ ++ G Q + + S + + S G ++S Sbjct: 2142 QSSRGERHGSSSG---SSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSH 2198 Query: 686 KQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNM 744 Q G+G + SS S+ + E G +SA+ + + + Sbjct: 2199 GQHGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQ 2250 Query: 745 WDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWG 804 + QSST ++T ++S+ H G G SS +G Sbjct: 2251 GQHGSTSGQSSTFDQEGSSTGQSSSHGQH--------------------GSGSSQSSSYG 2290 Query: 805 EMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAA 864 + + S PS +G ++ SGSGW G++ Sbjct: 2291 Q------QGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 2344 Query: 865 SALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGL 924 + +S Q G GSG + + +S S+SS G+ ++ L Sbjct: 2345 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSL 2404 Query: 925 QKGMKTSG 932 G SG Sbjct: 2405 GHGQHGSG 2412 Score = 88.6 bits (218), Expect = 5e-17 Identities = 204/966 (21%), Positives = 342/966 (35%), Gaps = 105/966 (10%) Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSN-GSAARVWGVATGSSSG 61 +GS + GH + +G + G S + S G G+ S S+ G +G SS Sbjct: 576 SGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATSGQSSS 635 Query: 62 LAHCSVSGGDGKMDTMIGDGRSQN-CWGASNSNAGINLNLNPNANPAAWPVL-GHEGTVA 119 G G Q+ G S+ G + + + + + W G G+V+ Sbjct: 636 HGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVS 695 Query: 120 TGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAW---GNLLPQESTEPQTSTSQNVSFSAQ 175 SS S GQ+ G +Q+G+ + + G+ Q S Q +S +S S Sbjct: 696 --GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSY- 752 Query: 176 PQNLNTDGPNNTNPMNSSPNPINAMQTNGLPN---WGMAVGMGAIIPPHLQGLPGANGSS 232 G + + SS + + P+ G + G + H G ++ Sbjct: 753 -------GQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCG 805 Query: 233 VSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFS-QG-NGDTVNSALSAKQNGSSS---- 286 + G A G G G G+++ FS QG +G T + S+ Q+ SSS Sbjct: 806 HYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865 Query: 287 ------AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVN 340 + SG SG PG G GSG + H G RS+S+G + Sbjct: 866 SYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG---RSSSSGRH 922 Query: 341 GEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSS 400 G +S K S+G +S T G H +S+ + S +S Sbjct: 923 GS-----GSGQSSGFGHKSSSG-QSSGYTQHG----SGSGHSSSYEQHGSRSGQSSRSEQ 972 Query: 401 DGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQT----PVKQ 456 GS + + S G+ G+G + G G Q P R +G GQ+ P + Sbjct: 973 HGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS---PSRGRHGSGSGQSSSYGPYRS 1029 Query: 457 NTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAA 516 + W P E + + + + +SG GS ++T G + ++ Sbjct: 1030 GSGWSSSRGP-YESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088 Query: 517 V---PANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573 A++G S+ + SG S + + GH G+ +++ SP++G Sbjct: 1089 CGQHGASSGQSSSHGQHGSGS---SQSSGYGRQGSGSGQSPGHGQRGSGSRQ--SPSYGR 1143 Query: 574 PPKPKSQHWGDGQRSNPAWSAGGGDWADS----SSVLGHLGDGKKNGSGWDADSNRSGSG 629 + GQ + + G +S SS G G + SG+ +RSG Sbjct: 1144 HGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQS 1203 Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVSNWGGAASVKQ 687 +SG S++ G+ ++ G Q + + S + + S G ++S Q Sbjct: 1204 SRGERHGSSSG---SSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQ 1260 Query: 688 TGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDG-TSAWGDPSNYNNKTVNMWD 746 G+G + SS S+ + E G +SA+ + + + Sbjct: 1261 HGSG--------SGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 1312 Query: 747 RNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEM 806 + QSS T + ++T +S+ HR G G SSG+G Sbjct: 1313 HGSTSGQSS-TFDQEGSSTGQSSSYGHR-------------------GSGSSQSSGYGR- 1351 Query: 807 PNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASA 866 S S G S S ++++G+ SGSGW G++ + Sbjct: 1352 HGAGSGQSPSRGRHGSGS----GHSSSYGQ-HGSGSGWSSSSGRHGSGSGQSSGFGHHES 1406 Query: 867 LCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQK 926 +S Q G GSG + + +S S+SS G+ ++ L Sbjct: 1407 SSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGH 1466 Query: 927 GMKTSG 932 G SG Sbjct: 1467 GQHGSG 1472 Score = 85.9 bits (211), Expect = 3e-16 Identities = 155/725 (21%), Positives = 268/725 (36%), Gaps = 97/725 (13%) Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63 S+ + +G+T+ +G+ ++G S S QS+ G +S GS++ +GS L Sbjct: 470 SSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529 Query: 64 HCSVSGGDGKMDTMI-----GDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTV 118 H G G+ + R + +G +G + + P + Sbjct: 530 HSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYES------------- 576 Query: 119 ATGNPSSICSPVSAIGQNMG-NQNGNPTGTLGAWGNLLPQESTEPQTST-SQNVSFSAQP 176 +G+ S + S GQ+ G Q+G+ +G G ST Q+S+ Q+ + S Q Sbjct: 577 GSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHGQ---HGSTSGQSSSCGQHGATSGQS 633 Query: 177 QNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG-----LPGANGS 231 + G ++ + Q+ G G + H G G +GS Sbjct: 634 SSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPHGS 693 Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK- 290 Q SG + S G S +G+S+S + +G + ++Q+GSSS + Sbjct: 694 VSGQSSGFGHKSGSGQSSGYS--QHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSS 751 Query: 291 ---------EGSGGNAWDSGPPAGPGILAWGRGSGN------NGVGNIHSGAWGHPSRST 335 + SG SG P + G SG+ +G G S + GH + Sbjct: 752 YGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGH--YES 809 Query: 336 SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTA 395 +G +G QH + G G S +SQ G+ +S +SSG ++ Sbjct: 810 GSGQASGFG----QHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSS 865 Query: 396 SEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVK 455 S G + + +H G GR G+G G+ GH Q +G GQ+P Sbjct: 866 SYGQHESASHHASG-RGRHGSGSGQ-------SPGHGQ-----------RGSGSGQSP-- 904 Query: 456 QNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPA 515 + S RS +G+ + + +S G++ G + + + S + Sbjct: 905 -SYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSR 963 Query: 516 AVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPP 575 + G S+ G G S S + + GH G+ + + SP+ G Sbjct: 964 S-------GQSSRSEQHGSSS-GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHG 1015 Query: 576 KPKSQHWGDG-QRSNPAWSAGGGDW---ADSSSVLGHLGDGKKNGSGWDADSNRSGSGWN 631 Q G RS WS+ G + + SS LGH SG+ + SG + Sbjct: 1016 SGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSG---H 1072 Query: 632 DTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQTG 689 +T + +++ G + G++ G + +S+ S +G G+ S + G Sbjct: 1073 SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQS-----SGYGRQGSGSGQSPG 1127 Query: 690 TGWIG 694 G G Sbjct: 1128 HGQRG 1132 Score = 85.9 bits (211), Expect = 3e-16 Identities = 160/714 (22%), Positives = 262/714 (36%), Gaps = 71/714 (9%) Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63 S+ G + +++ +G+ ++G S S QS+ G +S+GS++R +GS Sbjct: 2112 SSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171 Query: 64 HCSVSGGDGKMDTM----IGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVA 119 H G G + G G S + G S +G + + P + + + + Sbjct: 2172 HGRQGSGSGHSPSRGRHGSGSGHSSS-HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESG 2230 Query: 120 TGNPSSICSPVSAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQN 178 +G+ S+ S G Q+G+ +G + ST +S Q+ S S+Q + Sbjct: 2231 SGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ--EGSSTGQSSSHGQHGSGSSQSSS 2288 Query: 179 LNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANG-----SSV 233 G + + + + ++ G G + H G ++G SS Sbjct: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 2348 Query: 234 SQVSG----GSAEGISNSV--WGLSPGNPATGN---SNSGFSQG---NGDTVNSALSAKQ 281 Q SG GS G S+S G G + G S+SG S +G +L Q Sbjct: 2349 WQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQ 2408 Query: 282 NGSSSAVQ------KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRST 335 +GS S + GSG S P G G W G G+ HS GH R + Sbjct: 2409 HGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGS-GWSSSRGPYESGSGHSSGLGH--RES 2465 Query: 336 SNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT 394 +G + +G+ + +S +G+ GST +S S + H + ++ S Sbjct: 2466 RSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGY 2525 Query: 395 ASEGSSDG---------SGNHNEGSTGREGTGEGRRRDKGIIDQG--------HIQLPRN 437 +GS G SG+ S GR G+G GR G G H + Sbjct: 2526 GRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSG 2585 Query: 438 DLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEA-----WGCAATQASNSGGK 492 +G G + +S R ER + + G + Q+S G + Sbjct: 2586 QSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 2645 Query: 493 NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAP-----SGPGVWGDSISSTAVS 547 GS + + SG ++ +G G S+++ P V+G S + S Sbjct: 2646 GSGSGQSPSRGRHGSGLGHSSSHG-QHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHS 2704 Query: 548 TAAA---AKSGHAWSGA--ANQEDKSPTWGEPPKPKSQHWGDGQR-SNPAWSAG-GGDWA 600 +A + + SGH S + +S T+ + Q G R S + S+G G A Sbjct: 2705 SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGA 2764 Query: 601 DSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTN 654 S L H G +G + SGSG + SG G + G+N Sbjct: 2765 GSGQSLSHGRHGSGSGQSSSYGQHGSGSGQSSGYSQHGSGSGQDGYSYCKGGSN 2818 Score = 84.3 bits (207), Expect = 9e-16 Identities = 215/996 (21%), Positives = 362/996 (36%), Gaps = 123/996 (12%) Query: 4 GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62 GS G GH ++ +G+ QSPS + G+G ++S+G G G SSG Sbjct: 1119 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GSGLGESSGF 1167 Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVLGHEGTVATG 121 H S G + G G + +G S +G + + + + H G +G Sbjct: 1168 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSS--SHYGQHGSG 1225 Query: 122 NPSSIC----------SPV-----SAIGQNMGN-QNGNPTGTLGAWGNLLPQESTEPQTS 165 + S SP S +G + + Q+G+ +G + G P ES +S Sbjct: 1226 SRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG---PYESRSGHSS 1282 Query: 166 T-SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG 224 Q+ S S + G + + + + + Q++ G + G + Sbjct: 1283 VFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY------ 1336 Query: 225 LPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGS 284 G GS SQ SG G + G SP G S SG S G + + + +G Sbjct: 1337 --GHRGSGSSQSSGYGRHGAGS---GQSPSRGRHG-SGSGHSSSYGQHGSGSGWSSSSGR 1390 Query: 285 SSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344 + + SG +S G G GSG++ H G SR +G + Sbjct: 1391 HGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSS 1450 Query: 345 KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404 QH + G + S + Q+P+ G S ++ S + G S G Sbjct: 1451 SSYGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRG 1508 Query: 405 NHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEE 464 + GS+ +G G R + G+ Q ++ G T + ++ + Sbjct: 1509 PYESGSS--HSSGLGHRESRSGQSSGYGQ--HGSSSGHSSTHGQHGSTSGQSSSCGQHGA 1564 Query: 465 SPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWG 524 S S + + +G G ++Q+S G + GS + + SG P+ +G G Sbjct: 1565 S--SGQSSSHGQH--GSGSSQSSGYGRQGSGSGQSPGHGQRGSG-SRQSPSYGRHGSGSG 1619 Query: 525 DSNNKAPSGPGVW------------GDSISSTAVSTAAAAKSGHAWSGA-ANQEDKSPTW 571 S++ G G+ G S S + + + SG+ G+ + Q + Sbjct: 1620 RSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERH 1679 Query: 572 GEPPKPKS---QHWGDGQRSNPAWSAGGGDWADSS-----SVLGHLGDGKKNGSGWDADS 623 G + S QH ++S+ G G S S LGH ++GSG S Sbjct: 1680 GSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSS 1739 Query: 624 NR----SGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA--SKPQDNNVS 677 +R S SG + SG G+S + + G+ G G + + S D S Sbjct: 1740 SRGPYESRSGHSSVFGQHESGSGHS-SAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGS 1798 Query: 678 NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737 + G ++S Q G+G Q S G PS R +S++G + Sbjct: 1799 STGQSSSHGQHGSG-------SSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSG 1851 Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTH---RVETPPPHQAGT---QLNRSP 791 + + + + QSS + +++ ++ T H + Q G+ Q +R Sbjct: 1852 SGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGE 1911 Query: 792 LLGPGRKVSSGWGEMPN------VHSKTENSWGEPSSPST---LVDNGTAAWGKPPSSGS 842 G SS +G+ + H + + G+ SPS +G ++ P SGS Sbjct: 1912 QHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGS 1971 Query: 843 GWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQ-EGWGSGGDEMNLSTSQWEDEEGDVW 901 GW + P G +S L S+S Q G+G G S++ + Sbjct: 1972 GWSS--SRGPYESGSG----HSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQ------- 2018 Query: 902 NNAASQESTSSCSSWGNAPKKGLQKGMKTSGKQDEA 937 + +AS +S SSC G + + G SG + Sbjct: 2019 HGSASGQS-SSCGQHGASSGQSSSHGQHGSGSSQSS 2053 Score = 82.8 bits (203), Expect = 3e-15 Identities = 192/975 (19%), Positives = 352/975 (36%), Gaps = 136/975 (13%) Query: 5 SAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLA 63 S+ G +G+++ +G+ ++G S S QS+ G +S+GS++ +GS L Sbjct: 236 SSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLG 295 Query: 64 HCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNP 123 H G + + + G S +G + + + + +++ +G Sbjct: 296 HGRQGSGSRQSPSHVRHG----------SGSGHSSSHGQHGSGSSYSYSRGHYESGSGQT 345 Query: 124 SSICSPVSAIGQNMG-NQNGNPTG---TLGAWGNLLPQESTEPQ--TSTSQNVSFSAQPQ 177 S S GQ+ G +++G+ +G + G G+ Q S+ Q +S+ Q+ S+ Sbjct: 346 SGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHES 405 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNG------LPNWGMAVGMGAIIPPHLQGLPGANG- 230 + S +P + + +G G G + P++ G ++G Sbjct: 406 ASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGF 465 Query: 231 ---SSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS- 286 S S+ S G + S S G + + S + G + S+ S Q+GS S Sbjct: 466 GHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSR 525 Query: 287 ---AVQKEGSGG--------NAWDSGPPAGPGILAWGRGSGNNG------VGNIHSGAWG 329 + GSG +SG G GSG + G+ HS G Sbjct: 526 QSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLG 585 Query: 330 HPSRSTSNGVNGEWGKPPNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGEHMNSWAKA 388 H + + +G + +G+ + +S +G+ GST +S S G+H Sbjct: 586 H--QESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSC----------GQH------G 627 Query: 389 ASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGI--IDQGHIQLPRNDLDPRVLSN 446 A+SG ++S G GSG+ G++G+G G+ +G D GH + + S Sbjct: 628 ATSGQSSSHG-QHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGH-----SSSYGQHGSG 681 Query: 447 TGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG-KNDGSIMNSTNTSS 505 +GW + + + S + + + + +S+S G + GS ++ S Sbjct: 682 SGWSSSNGPHGSV-SGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE 740 Query: 506 VSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQE 565 G + + ++ G S + SG G G + + SGH+ S + Sbjct: 741 QHG----SSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGS 796 Query: 566 DK--SPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADS 623 S + G Q G GQ S G ++ S GH ++GS Sbjct: 797 GTSCSSSCGHYESGSGQASGFGQHE----SGSGQGYSQHGSASGHFSSQGRHGS---TSG 849 Query: 624 NRSGSGWNDTTRSGNSGWG------NSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVS 677 S SG +D++ +S +G + + + G+ G++ PG Q + Q + Sbjct: 850 QSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQS--PGHGQRGSGSGQSPSYG 907 Query: 678 NWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNY 737 G+ S + + +G G S +++G+ S G + G S + Sbjct: 908 R-HGSGSGRSSSSGRHG-------SGSGQSSGFGHKSSSG------QSSGYTQHGSGSGH 953 Query: 738 NNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGR 797 ++ R+ QSS + +++ +++S H G G Sbjct: 954 SSSYEQHGSRSG---QSSRSEQHGSSSGSSSSYGQH--------------------GSGS 990 Query: 798 KVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGR 857 + S G G+ H PS +G ++ P SGSGW G Sbjct: 991 RQSLGHGQ----HGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGH 1046 Query: 858 AGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG 917 + + +S Q G SG + + + AS +SS G Sbjct: 1047 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1106 Query: 918 NAPKKGLQKGMKTSG 932 + + G + SG Sbjct: 1107 SGSSQSSGYGRQGSG 1121 Score = 77.4 bits (189), Expect = 1e-13 Identities = 149/712 (20%), Positives = 259/712 (36%), Gaps = 81/712 (11%) Query: 4 GSAQGNFTGHTKKTNGNNGTNGALVQSPS-NQSALGAGGANSNGSAARVWGVATGSSSGL 62 GS G GH ++ +G+ QSPS + G+G ++S+G G G SSG Sbjct: 2059 GSGSGQSPGHGQRGSGSR-------QSPSYGRHGSGSGRSSSSGQH----GPGLGESSGF 2107 Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVL--------- 112 H S G + G G + +G S +G + + + + Sbjct: 2108 GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSR 2167 Query: 113 -----GHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTST- 166 G +G+ + +PS + + Q+G+ +G + G P ES +S Sbjct: 2168 QSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRG---PYESRSGHSSVF 2224 Query: 167 SQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLP 226 Q+ S S + G + + + + + Q++ G + G + H G Sbjct: 2225 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSG-- 2282 Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS 286 + SS Q GS + S G +G+S+S G+G +S S+ ++GS S Sbjct: 2283 SSQSSSYGQQGSGSGQSPSRGRHG-----SGSGHSSSYGQHGSGSGWSS--SSGRHGSGS 2335 Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP 346 + SG +S G G GSG++ H G SR +G + Sbjct: 2336 G---QSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSS 2392 Query: 347 PNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNH 406 QH + G + S + Q+P+ G S ++ S + G S G + Sbjct: 2393 YGQHGSGSRQSLGH--GQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450 Query: 407 NEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESP 466 GS G G R ++G+G Q+ + S Sbjct: 2451 ESGSGHSSGLGHRESRSG--------------------QSSGYG-----QHGSSSGHSST 2485 Query: 467 RSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDS 526 + + +G ++ C AS+ + G + ++ SS G + P + G Sbjct: 2486 HGQHGSTSG-QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 2544 Query: 527 NNKAPS-GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDG 585 + ++PS G G SS++ + + + +S ++ + G G Sbjct: 2545 SRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG 2604 Query: 586 QR-SNPAWSAGG---GDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGW 641 Q S S+ G G + SSS G G G + SG SGSG + + SG Sbjct: 2605 QHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQG--SGSGQSPSRGRHGSGL 2662 Query: 642 GNSTNTKANPGTNWGETLKPGPQQN--WASKPQDNNVSNWGGAASVKQTGTG 691 G+S ++ G+ G + GP ++ S + S G +++ Q G+G Sbjct: 2663 GHS-SSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSG 2713 Score = 74.3 bits (181), Expect = 9e-13 Identities = 192/924 (20%), Positives = 336/924 (36%), Gaps = 140/924 (15%) Query: 61 GLAHCSVSGGDGKMDT-----------MIGDGRSQNCWGASNSNAGINLNLNPNANPAAW 109 G +C VSG + DT + R ++ + S+ +AG N + + N + Sbjct: 90 GKDYCQVSGSKLRDDTHQHQEEQEETEKEENKRQESSFSHSSWSAGENDSYSRNVRGSLK 149 Query: 110 PVLGHEGTVA--------TGNPSSICSPVSAIG-QNMGNQNGNPTGTLGAWGNLLPQEST 160 P G E +G +S S+ G QN + + G G+ P Sbjct: 150 P--GTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSP---- 203 Query: 161 EPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPP 220 + Q+ S S Q + +T G + S + ++ Q++G G G + Sbjct: 204 ----NYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQ 259 Query: 221 HL----QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGN----------SNSGFS 266 H Q G S S S + S S L G +G+ S SG S Sbjct: 260 HGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHS 319 Query: 267 QGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSG 326 +G + + + G + + SG +SG G G GSG++ H Sbjct: 320 SSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGS 379 Query: 327 AWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKG-----STGWESP------SVTSQNPTV 375 G S S +G + QH ++ + G S +SP S + Q+P+ Sbjct: 380 TSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPS- 438 Query: 376 QPGGEHMNSWAKAASSGTTAS-EGSSDGSGNH---NEGSTGREGTGEGRRRDKGIIDQGH 431 G+H + +++SSG S G S G G+H +E S+G G G GH Sbjct: 439 --SGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQHGSG---------SGH 487 Query: 432 IQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG 491 ++G GQ + +S R ER+ G +A +S+ G Sbjct: 488 --------------SSGHGQHGSRSG------QSSRGERQ--------GSSAGSSSSYGQ 519 Query: 492 KNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAA 551 GS + ++ SG +P + G +S ++ S G G ++ Sbjct: 520 HGSGSRQSLGHSRHGSGSGQSP----SPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYE 575 Query: 552 AKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGG--GDWADSSSVLGHL 609 + SGH+ SG +QE +S +S +G S+ S G G + SS G Sbjct: 576 SGSGHS-SGLGHQESRS--------GQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQH 626 Query: 610 GDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTN-TKANPGTNWGETL---KPGPQQ 665 G SG + + GSG + ++R G G G+ + ++ G+++G + + G Sbjct: 627 G----ATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGS 682 Query: 666 NWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEID 725 W+S + + + ++G+G G SS ++G+ + S + Sbjct: 683 GWSSSNGPHGSVSGQSSGFGHKSGSGQSSG-YSQHGSGSSHSSGYRKHGSRSGQSSRSEQ 741 Query: 726 DGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGT 785 G+S+ G S+Y + Q S + ++ + +S + + H +GT Sbjct: 742 HGSSS-GLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSS--SGHSSSHGQHGSGT 798 Query: 786 QLNRS-PLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSG--- 841 + S G +SG+G+ + + + G S + + G+ SSG Sbjct: 799 SCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHD 858 Query: 842 ------SGWGDHPAEPPVAFGR----AGAPVAASALCKPASKSMQEGWGSGGDEMNLSTS 891 S +G H + A GR +G+ + + + +G G S+S Sbjct: 859 SSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSS 918 Query: 892 QWEDEEGDVWNNAASQESTSSCSS 915 G ++ +S+S SS Sbjct: 919 SGRHGSGSGQSSGFGHKSSSGQSS 942 Score = 54.3 bits (129), Expect = 1e-06 Identities = 85/372 (22%), Positives = 132/372 (35%), Gaps = 32/372 (8%) Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62 +GS + GH + +G + G S + S G G+ S G SS Sbjct: 2452 SGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTS------------GQSSSC 2499 Query: 63 AHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAW-PVLGHEGTVAT 120 S G G G SQ+ +G S +G + + + P G G+ + Sbjct: 2500 GQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGS-GS 2558 Query: 121 GNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS-TSQNVSFSAQPQNL 179 G SS S +G++ G G+ + G + S +S Q+ S S Q Sbjct: 2559 GRSSSSGQHGSGLGESSG--FGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616 Query: 180 NTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239 G ++ + + + + Q++G G G H GL + SS Q G Sbjct: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGL--GHSSSHGQHGSG 2674 Query: 240 SAEGIS----------NSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQ 289 S S +SV+G ++ S G+G + +G SS Sbjct: 2675 SGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFD 2734 Query: 290 KEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWG-HPSRSTSNGVNGEWGKPPN 348 +EGS S G G + G G +G G+ S + G H S S + G+ G Sbjct: 2735 QEGSSTGQSSSYGHRGSG-SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGSG 2793 Query: 349 QHSNSDINGKGS 360 Q S +G GS Sbjct: 2794 QSSGYSQHGSGS 2805 Score = 35.8 bits (81), Expect = 0.36 Identities = 90/484 (18%), Positives = 164/484 (33%), Gaps = 53/484 (10%) Query: 454 VKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAP 513 ++ +T EE +E++ + E+ + + +S S G+ND N S+ + Sbjct: 101 LRDDTHQHQEEQEETEKEENKRQES---SFSHSSWSAGENDSYSRNVRG--SLKPGTESI 155 Query: 514 PAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGE 573 + + +N +G+ S + S+ G SG+ +SP +G+ Sbjct: 156 SRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGR----GQCGSGSG----QSPNYGQ 207 Query: 574 PPKPKSQH-----WGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628 Q G G + +S SS H G G + SG+ +RSG Sbjct: 208 HGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQH-GSGSGHSSGYGQHGSRSGQ 266 Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688 +SG S+++ G+ ++L G +Q S+ ++V + G+ Sbjct: 267 SSRGERHRSSSG---SSSSYGQHGSGSRQSLGHG-RQGSGSRQSPSHVRHGSGSGHSSSH 322 Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRN 748 G G + +G TS +G + + ++ Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQ-----------------TSGFGQHESGSGQSSGYSKHG 365 Query: 749 NPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPN 808 + SS+ +T+ +S+ H + G + S + SSG G+ P Sbjct: 366 SGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGSGQSPG 425 Query: 809 VHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALC 868 + S PSS G ++ P SGSG+ FG + Sbjct: 426 HGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSS-------GFGH------HESSS 472 Query: 869 KPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKGLQKGM 928 + +S Q G GSG + + +S S+SS G+ ++ L Sbjct: 473 EHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSR 532 Query: 929 KTSG 932 SG Sbjct: 533 HGSG 536 >gi|62122917 filaggrin family member 2 [Homo sapiens] Length = 2391 Score = 84.3 bits (207), Expect = 9e-16 Identities = 203/944 (21%), Positives = 343/944 (36%), Gaps = 126/944 (13%) Query: 12 GHTKKTNGNNGTNGALVQSPSNQSAL----GAGGANSNGSAARVWGVA-----TGSSSGL 62 G+ + NG G ++ S+QS+ G+GG+ S + +G + SS+ Sbjct: 354 GYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413 Query: 63 AHCSVSGGDGKMDTMI---GDGRSQNCW------------GASNSNAGINLNLNPNANPA 107 + C G T G G SQ+ G S + +L + + + + Sbjct: 414 SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSS 473 Query: 108 AWPV-LGHEGTVATGNPSSICSPVSAIGQNMG-NQNGNPTGT---LGAWGNLLPQ----- 157 G G+ +G S S GQ+ G Q+G+ +G G G++ Q Sbjct: 474 GKTSGFGQHGS-GSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFG 532 Query: 158 --ESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMG 215 ES Q+S Q+ S S+Q G T+ + + + Q+ G +G G Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQ--HGLGSGQSTGFGQYGSGSGQS 590 Query: 216 AIIPPHLQGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVN 274 + G +GS Q SG G E S G + G +SG SQ +G Sbjct: 591 SGF--------GQHGSGSGQSSGFGQHESRS--------GQSSYGQHSSGSSQSSG---- 630 Query: 275 SALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRS 334 Q+GS ++ SG SG G +G GSG + SG H S S Sbjct: 631 ----YGQHGS-----RQTSGFGQHGSGSSQSTGFGQYGSGSGQS------SGFGQHVSGS 675 Query: 335 TSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT 394 + G+ S S + G G+ S + G+ SSG + Sbjct: 676 GQSSGFGQ------HESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQS 729 Query: 395 ASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPV 454 +S G GSG+ G+ G+G G+ G + Q ++G+GQ Sbjct: 730 SSFG-QHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGS 788 Query: 455 KQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPP 514 +Q + + S S+ G +G + Q++ G GS SG+ Sbjct: 789 RQTSGFGQHGSGSSQ---STGFGQYGSGSGQSAGFGQHGSGS-------GQSSGFGQHES 838 Query: 515 AAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQ---EDKSPTW 571 + ++ G S + SG G G S T+ + SG +SG +S + Sbjct: 839 RSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQ-YSGFGQHGSGSGQSSGF 897 Query: 572 GEPPKPKSQHWGDGQ-RSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW 630 G+ Q+ G GQ S S+ G + SS G+ G +G + +RSGSG Sbjct: 898 GQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQ 957 Query: 631 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQT 688 + SG G S+ + + G + ++ SN+G G+ S + + Sbjct: 958 SSGFGQHGSGSGQSSGFGQHESGS-------GKSSGFGQHESRSSQSNYGQHGSGSSQSS 1010 Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPS-----IRRKMEIDDGTSAWGDPSNYNNKTVN 743 G G G S + TG+ + S + D +S +G + ++ Sbjct: 1011 GYGQHG-------SSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSG 1063 Query: 744 MWDRNNPVIQSSTTTNTTTTTTTT----TSNTTHRVETPPPHQAGT-QLNRSPLLGPGRK 798 + QSS + + ++ ++ + + + H+ G+ Q + G G Sbjct: 1064 FGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSG 1123 Query: 799 VSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGR- 857 SSG+G+ + K+ + + + S G G SSG G + + P +FG+ Sbjct: 1124 QSSGFGQHGSGTGKS-SGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQH 1182 Query: 858 -AGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDV 900 +G+ +S+ + G+G G ST + E V Sbjct: 1183 VSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQV 1226 Score = 69.7 bits (169), Expect = 2e-11 Identities = 167/779 (21%), Positives = 275/779 (35%), Gaps = 138/779 (17%) Query: 4 GSAQGNFTGHTKKTNGNNGTNG-ALVQSPSNQSALGAGGANSNGSAAR-VWGVATGSSSG 61 GS G +G + G+ +G +S S+QS+ G G+ S+ S+ G ++G + G Sbjct: 888 GSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFG 947 Query: 62 LAHCSVSGGDGKMDTMIGDGRSQNC-WGASNSNAGINLNLNPNANPAAWPVLGHEG---- 116 G G G Q+ +G S +G + + + ++ G G Sbjct: 948 FGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSS 1007 Query: 117 --------------TVATGNPSSICSPVSAIGQNMGN--------QNGNPTGTLGAWGNL 154 T G S S GQ+ Q+G +G +G Sbjct: 1008 QSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQY 1067 Query: 155 LPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGM 214 ES Q+S Q+ S S+Q G N+ + + Q++G +G G Sbjct: 1068 ---ESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQ 1124 Query: 215 GAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSG----FSQGNG 270 + H G ++G + + G + S G TG+S S G+G Sbjct: 1125 SSGFGQHGSGTGKSSGFAQHEYRSGQS----------SYGQHGTGSSQSSGCGQHESGSG 1174 Query: 271 DTVNSA--LSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNN-GVGN----- 322 T + +S N SSS G + DSG G G +G GSG + G+G Sbjct: 1175 PTTSFGQHVSGSDNFSSS-------GQHISDSGQSTGFG--QYGSGSGQSTGLGQGESQQ 1225 Query: 323 IHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHM 382 + SG+ H + T++G +HS S G+G + VT + + Q Sbjct: 1226 VESGSTVHGRQETTHGQTIN----TTRHSQS---GQGQSTQTGSRVTRRRRSSQSENSDS 1278 Query: 383 NSWAKAASSGTTASEGSSDGSGNH--NEGST--GREGTGEGRRRDKGIIDQGHIQLPRND 438 +K + SE +G+H GST R+GT G+R D GH Sbjct: 1279 EVHSKVSHRH---SEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDT--TRHGH------- 1326 Query: 439 LDPRVLSNTGWGQ---TPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDG 495 +G GQ T + + F S ++ + +G + Q + G G Sbjct: 1327 --------SGHGQSTQTGSRTSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHG 1378 Query: 496 SIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSG 555 ++ + + + A ++G G S + + +G Sbjct: 1379 ESESTVHERHETTYGQTGEATGHGHSGHGQSTQRG--------------------SRTTG 1418 Query: 556 HAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGD---- 611 SG + D G +P+SQ GQ + +G + G GD Sbjct: 1419 RRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQTGDTTRH 1478 Query: 612 -----GKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNST---NTKANPGTNWGETLKPGP 663 GK G + + R GSG ++++ S G+ T +T G+ GE+ Sbjct: 1479 AHYHHGKSTQRG-SSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIH 1537 Query: 664 QQNWASKPQ--DNNVSNWGGAASVKQTGTGWIGGPVPVKQKDS-SEATGWEEPSPPSIR 719 ++ + Q D ++ G QTG+ G +Q+ S SE+T E S S R Sbjct: 1538 DRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTG-----RQRTSHSESTDSEVHSGGSHR 1591 Score = 54.3 bits (129), Expect = 1e-06 Identities = 103/479 (21%), Positives = 165/479 (34%), Gaps = 63/479 (13%) Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNG--- 283 G SG S G S G+ TG SG S+ + V+S S +G Sbjct: 1845 GTTHGQTGDTSGHSQSGHGQST---QSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTH 1901 Query: 284 ---------SSSAVQKE-----GSGGNAWDSGPPA-GPGILAWGRGSGNNGVGNIHSGAW 328 S S V K G G+ + G P+ G I R +G G G+ Sbjct: 1902 SQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHGQTIQTGSRTTGRRGSGHSEYSDS 1961 Query: 329 GHPS---RSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVT----SQNPTVQPGGEH 381 PS + S +G+ G + +S G+T ++ T S + G Sbjct: 1962 EGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSR 2021 Query: 382 MNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDP 441 + S + SEG S S H+ + G+ G+ G + + H D Sbjct: 2022 TTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSS--VHERHGTTHGQTGDT 2079 Query: 442 RVLSNTGWGQTPVKQNTAWEFEESPRSERKND---------NGTEAWGCAATQASNSGGK 492 +++G GQ+ + + S SE + + +G A +Q SG Sbjct: 2080 TRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSA 2139 Query: 493 ---NDGSIMNSTNTSSVSGWVNAPPAAVPAN--TGWGDSNNKAPSGPGVWGDSISSTAVS 547 G+I T ++ G + + TG S++ S V ++ + + Sbjct: 2140 IHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGH 2199 Query: 548 TAAAAKSGHAWSGAANQEDKSPTWGEP-PKPKSQHWGDGQRSNPAWSAGG---------- 596 T + A S H SG++ + T G+ + H+G GQ + G Sbjct: 2200 THSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESS 2259 Query: 597 -------GDWADSSSVLGHLGDGKKN-GSGWDADSNRSGSGWNDTTRSGNSGWGNSTNT 647 G S + G G ++ GS + DTTR G+SG+G ST T Sbjct: 2260 DSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQT 2318 Score = 52.0 bits (123), Expect = 5e-06 Identities = 142/690 (20%), Positives = 237/690 (34%), Gaps = 83/690 (12%) Query: 9 NFTGHTKKTNGNNGTNGA--LVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCS 66 +++GH + T + T G S S S + +GG++ S +G A GS + Sbjct: 1554 SYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYGQA-GSQHEEPEFT 1612 Query: 67 VSGGDGKMDTMIGD--GRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPS 124 V G IGD G S + G S +++ + H G T Sbjct: 1613 VHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHT---- 1668 Query: 125 SICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGP 184 + G+ +G G +++P+ T + L T Sbjct: 1669 -----------HTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTTRHAHYHHGLTTQTG 1717 Query: 185 NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGI 244 + T S G + + G + H +G + SQ G +E I Sbjct: 1718 SRTTGRRGS----------GHSEYSDSEGYSGVSHTHSGH---THGQARSQ--HGESESI 1762 Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPA 304 + G G TG++ G+G + + SS + S G++ S P Sbjct: 1763 VHERHGTIHGQ--TGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPH 1820 Query: 305 GPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW-GKPPNQHSNSDINGKGSTGW 363 G GS + +I G T++G G+ G + H S +G +TG Sbjct: 1821 SRGHTHGQAGSQHGESESIVDERHG-----TTHGQTGDTSGHSQSGHGQSTQSGSSTTGR 1875 Query: 364 E-SPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNE-----GSTGREG-- 415 S S + V GG H +S + + + E S H G T G Sbjct: 1876 RRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHP 1935 Query: 416 ----TGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERK 471 T + R G GH + ++ P +S+T G T + + + ES S + Sbjct: 1936 SHGQTIQTGSRTTGRRGSGHSEYSDSE-GPSGVSHTHSGHTHGQAGS--HYPESGSSVHE 1992 Query: 472 NDNGTEAWGCAATQASNSG---GKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNN 528 T T+ +SG GS S S + ++ + ++T G ++ Sbjct: 1993 RHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHG 2052 Query: 529 KAPSGPGVWGDSI----SSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQ---- 580 +A S G G S+ +T T + H+ G + Q S T G S+ Sbjct: 2053 QAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRG-SRTAGRRGSGHSESSDS 2111 Query: 581 ---------HWGD--GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG 629 H G GQ + +G ++ G GD ++G S ++GS Sbjct: 2112 EVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSR 2171 Query: 630 WNDTTRSGNSGWGNS-TNTKANPGTNWGET 658 RS +S +S +++A+P T+ G T Sbjct: 2172 TTGRQRSSHSESSDSEVHSEASP-THSGHT 2200 Score = 46.2 bits (108), Expect = 3e-04 Identities = 123/651 (18%), Positives = 217/651 (33%), Gaps = 67/651 (10%) Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGV 339 + N + S ++++ G + SG G ++ G +S G P ++S+ Sbjct: 250 ESNSTQSRIREQKLGSSCSGSGDS----------GRRSHACGYSNSSGCGRPQNASSSCQ 299 Query: 340 NGEWGKPPNQHS------NSDINGKGSTGWES---PSVTSQNPTVQPGGEHMNSWAKAAS 390 + +G NQ S S I G G S PS Q + + A Sbjct: 300 SHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRGYGARE 359 Query: 391 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 450 +G + G +G+ G+ G+G + G + G N S Sbjct: 360 NGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQY 419 Query: 451 QTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWV 510 + Q+T++E + S+ +G E C + Q + S SG Sbjct: 420 GSGSSQSTSFEQHGTGLSQ---SSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKT 476 Query: 511 NAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPT 570 + +G G S+ G G G S + + SG G+ + + Sbjct: 477 SG---FGQHGSGSGQSSGFGQCGSGS-GQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFG 532 Query: 571 WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH-LGDGKKNGSGWDADSNRSGSG 629 E +S + G S+ + G ++S H LG G+ G G + SG Sbjct: 533 QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSG 592 Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQ 687 + G + + +++G+ Q + + S +G G+ S + Sbjct: 593 FGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQS 652 Query: 688 TGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDR 747 TG G G +G + S + E G S++G ++++ Sbjct: 653 TGFGQYGSGSGQSSGFGQHVSGSGQSSGFG---QHESRSGHSSYGQHGFGSSQSSGYGQH 709 Query: 748 NNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMP 807 + Q+S ++ ++S H + G G G SSG+G+ Sbjct: 710 GSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQH-------GSGSGQSSGFGQ-- 760 Query: 808 NVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASAL 867 + ++S+G+ SS S S SG+G H + FG+ G Sbjct: 761 HESRSGQSSYGQHSSGS--------------SQSSGYGQHGSRQTSGFGQHG-------- 798 Query: 868 CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQ-ESTSSCSSWG 917 + S G+G G S + G ++ Q ES S SS+G Sbjct: 799 ---SGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYG 846 Score = 39.3 bits (90), Expect = 0.033 Identities = 148/714 (20%), Positives = 243/714 (34%), Gaps = 101/714 (14%) Query: 252 SPGNPATGNSNSGFSQGNGDTVNSALSAK----QNGSSSAVQKEGSGGNAWDSGPPAGPG 307 +PG+ + G +S +S+G +S S ++GS+S ++ G GN SG G Sbjct: 122 TPGHKS-GYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNS--RRLGRQGNLSSSGNQEGSQ 178 Query: 308 ILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPS 367 G++ G G S +N P + +G GS WE Sbjct: 179 KRYHRSSCGHSWSGG--KDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKG 236 Query: 368 VTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDG-SGNHNEGSTGREGTGEGRRRDKGI 426 + ++ G NS S S G SG + +G GR ++ Sbjct: 237 HGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCGRPQNASS 296 Query: 427 IDQGH--------IQLPRNDLDPRVLSNTGWGQTPVKQ-NTAWEFEESPRSERKNDNGTE 477 Q H ++ + G G Q + + E +P S+ + G Sbjct: 297 SCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQSYSQRG-- 354 Query: 478 AWGCAAT-QASNSGGK-NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPG 535 +G Q N GG+ GS +S SG + G +N + S Sbjct: 355 -YGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEF 413 Query: 536 VWGDSISSTAVSTAAAAKSGHAWSGAANQED----KSPTWGEPPKPKSQHWGDGQRSNPA 591 D S + + + + G S ++ E T G+ SQ G Q + + Sbjct: 414 SKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSS 473 Query: 592 WSAGG----GDWADSSSVLGHLGDGKKNGSGW----DADSNRSGSGWNDTTRSGNSGWGN 643 G G + SS G G G SG+ SG G + + +SG+G Sbjct: 474 GKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQ 533 Query: 644 STNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWG--GAASVKQTGTGWIGGPVPVKQ 701 + +++G+ Q + + S +G G S + TG G G Sbjct: 534 HESRSRQ--SSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYG------- 584 Query: 702 KDSSEATGWEEPSPPSIRR----KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTT 757 S +++G+ + S + + E G S++G S+ ++ QSS Sbjct: 585 SGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSS-------------QSSGY 631 Query: 758 TNTTTTTTTTTSNTTHRVETPPPHQAG-TQLNRSPLLGPGRKVSSGWGEMPNVHSKTENS 816 + T+ H +G +Q G G SSG+G+ + S + Sbjct: 632 GQHGSRQTSGFGQ----------HGSGSSQSTGFGQYGSGSGQSSGFGQHVS-GSGQSSG 680 Query: 817 WGEPSSPSTLVDNGTAAWGKPPSSG-----------SGWGDH--PAEPPVAFGRAGAPVA 863 +G+ S S G +G SSG SG+G H + +FG+ G+ Sbjct: 681 FGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSG 740 Query: 864 ASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSSWG 917 S S Q G GSG +S + E ++ Q S+ S S G Sbjct: 741 QS------SGFGQHGSGSG------QSSGFGQHESRSGQSSYGQHSSGSSQSSG 782 Score = 35.8 bits (81), Expect = 0.36 Identities = 114/508 (22%), Positives = 177/508 (34%), Gaps = 82/508 (16%) Query: 227 GANGSSVSQV-SGGS--------AEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSAL 277 G + SS S+V SGGS G + S G S G+ G + Q GDT A Sbjct: 1423 GHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGES-GSTVHGRHGTTHGQ-TGDTTRHAH 1480 Query: 278 ----SAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSR 333 + Q GSS+ ++ + DS +G G G +G + S + H Sbjct: 1481 YHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDRH 1540 Query: 334 STSNGVNGEWGKPP-NQHSNSDINGKGSTGWESPSVT-SQNPTVQPGGEHM-----NSWA 386 ++G G+ + + H + G +TG + S + S + V GG H +++ Sbjct: 1541 RITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHSGGSHRPHSREHTYG 1600 Query: 387 KAASS------------GTTASE-GSSDGSGNHNEG-STGREGTGEGRRRDKGIIDQGHI 432 +A S GTT + G + G + G ST R GR+R H Sbjct: 1601 QAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQRSS------HS 1654 Query: 433 QLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGG- 491 + +++ V S+T G T + + ES ER + G A G Sbjct: 1655 ESSDSEVHSGV-SHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQT-GDTTRHAHYHHGL 1712 Query: 492 -KNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGD-------SISS 543 GS S S + ++ + ++T G ++ +A S G +I Sbjct: 1713 TTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESESIVHERHGTIHG 1772 Query: 544 TAVSTAAAAKSGHAWS-------------GAANQEDKSPTWGEPPKPKSQHWGDGQRSNP 590 T A SGH S G + D G +P S+ GQ Sbjct: 1773 QTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTHGQ---- 1828 Query: 591 AWSAGGGDWADSSSVL--------GHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWG 642 G +S S++ G GD + S +SGS RSG+S Sbjct: 1829 ----AGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHSESS 1884 Query: 643 NSTNTKANPGTNWGETLKPGPQQNWASK 670 +S T+ G T Q+ S+ Sbjct: 1885 DSEVHSGGSHTHSGHTHSQARSQHGESE 1912 >gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] Length = 1301 Score = 77.0 bits (188), Expect = 1e-13 Identities = 140/802 (17%), Positives = 315/802 (39%), Gaps = 44/802 (5%) Query: 5 SAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANS-----NGSAARVWGVATGSS 59 S QG+ + ++NGN+ N +S +N S+ G NS NG+ + G S Sbjct: 459 SMQGDDPNSSDESNGNDDANS---ESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDS 515 Query: 60 SGLAHCSVS-----------------GGDGKMDTMIGDGR-SQNCWGASNSNAGINLNLN 101 + + S G GK D+ D S N +S+S+ + + N Sbjct: 516 DSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN 575 Query: 102 PNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTE 161 +++ + + + + + SS S S + + + + + + + +S++ Sbjct: 576 SSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSD 635 Query: 162 P--QTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIP 219 ++ +S + S + + ++D N++N +SS + ++ ++ + + + Sbjct: 636 SDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDS 695 Query: 220 PHLQGLPGANGSSVSQVSGGSAEGISNSVWG-LSPGNPATGNSNSGFSQGNGDTVNSALS 278 + ++ SS S S S SNS S + ++ +SNS S + D+ NS+ S Sbjct: 696 SNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDS 755 Query: 279 AKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNG 338 + + SS++ S ++ S S ++ N + S +S+ Sbjct: 756 SDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815 Query: 339 VNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEG 398 + + + ++SD + ++ S S S + + +S + SS ++ S Sbjct: 816 SDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSN 875 Query: 399 SSDGS--GNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQ 456 SSD S + NE S + + D D N D SN+ Sbjct: 876 SSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS------NSSDSSDSSNSSDSSESSNS 929 Query: 457 NTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAA 516 + +S S +D+ + ++ +S+S +D S NS+++S S ++ ++ Sbjct: 930 SDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS 989 Query: 517 VPANTG-WGDSNNKAPSGPGV-WGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP 574 +++ DS+N + S DS +S+ S ++ + + S +++ D S + Sbjct: 990 DSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSS 1049 Query: 575 PKPKSQHWGD----GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW 630 S + D S+ + S+ D +DSS + S +DS+ S Sbjct: 1050 DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSS 1109 Query: 631 NDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGT 690 + + S +S NS+++ + ++ + +S+ D++ S+ +S + Sbjct: 1110 DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSS 1169 Query: 691 GWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNP 750 DSS+++ + S S D S+ S+ ++ + + D ++ Sbjct: 1170 DSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSS-DSSDSSDSSDSSDSSDSSDSSDSSDS 1228 Query: 751 VIQSSTTTNTTTTTTTTTSNTT 772 + ++ ++ ++ ++ +SN++ Sbjct: 1229 SDSNESSDSSDSSDSSDSSNSS 1250 Score = 69.3 bits (168), Expect = 3e-11 Identities = 109/679 (16%), Positives = 263/679 (38%), Gaps = 30/679 (4%) Query: 3 TGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGL 62 + S+ + + ++ ++ ++ + S S+ S+ + +NS+ S+ + SS Sbjct: 645 SNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDS 704 Query: 63 AHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGN 122 + S S D+ + + +S+S+ N + + +++ ++ + + ++ + Sbjct: 705 SDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNS 764 Query: 123 PSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTD 182 S S S+ + N + + + + + S +S S + S S+ + N+ Sbjct: 765 SDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSS 824 Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAE 242 +N++ + S N ++ ++ + + ++ SS S S S++ Sbjct: 825 DSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNR------SDSSNSSDSSDSSDSSNSSD 878 Query: 243 GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP 302 +S S + + +S++ + D+ NS+ S+ + SS + + S N+ S Sbjct: 879 SSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSD- 937 Query: 303 PAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTG 362 S ++ + + S ++S+ N N +SD + + Sbjct: 938 -----------SSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSS 986 Query: 363 WESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRR 422 S S S + + + + ++ S ++ +S S N ++ S + + Sbjct: 987 DSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSS 1046 Query: 423 DKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCA 482 D D + D S++ + + E +S S +D+ + Sbjct: 1047 DSS--DSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104 Query: 483 ATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSIS 542 ++ +S+S +D S +S+N+S S ++ ++ +N+ DS++ + S DS Sbjct: 1105 SSDSSDSSDSSDSS--DSSNSSDSSDSSDSSDSSDSSNSS--DSSDSSESSDS--SDSSD 1158 Query: 543 STAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAW----SAGGGD 598 S+ S ++ + S ++N D S + S D S+ + S+ D Sbjct: 1159 SSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1218 Query: 599 WADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGET 658 +DSS + + S +DS+ S + + + S +S + +N +++ + G Sbjct: 1219 SSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNG 1278 Query: 659 LKPGPQQNWASKPQDNNVS 677 G + S+ D+N S Sbjct: 1279 NNNGSDSDSDSEGSDSNHS 1297 Score = 65.9 bits (159), Expect = 3e-10 Identities = 179/918 (19%), Positives = 313/918 (34%), Gaps = 146/918 (15%) Query: 82 RSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQN 141 +S N + SN + LN + VL HEG + G Sbjct: 30 KSMNLHLLARSNVSVQDELNASGTIKESGVLVHEGDRGRQENTQDGHKGEGNGSKWAEVG 89 Query: 142 GNPTGTLGAW----GNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPI 197 G T GN+ + T + + +N+ +G + + Sbjct: 90 GKSFSTYSTLANEEGNIEGWNGDTGKAETYGHDGIHGKEENITANGIQGQVSIIDNAGAT 149 Query: 198 NAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-SVSQVSGGSAEGISNSVWGLSPGNP 256 N TNG N G + G G N +V Q G G +NS N Sbjct: 150 NRSNTNG--NTDKNTQNGDV------GDAGHNEDVAVVQEDGPQVAGSNNST-----DNE 196 Query: 257 ATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAW---DSGPPAGPGI----- 308 NS ++GN + +++K+NG+ A G+G +A G P+G G Sbjct: 197 DEIIENSCRNEGNTSEITPQINSKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDED 256 Query: 309 ----------LAWGRGSGNNG---VGNIHSGAWGHPSRSTSNGVNGEWGKPPNQ---HSN 352 G+ S NN G H H S N + E+ P + H+ Sbjct: 257 EGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNE 316 Query: 353 SDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK-------------AASSGTTASEGS 399 D + + S + N G + + K S T A S Sbjct: 317 VDGDKTSKSEENSAGIPEDN-----GSQRIEDTQKLNHRESKRVENRITKESETHAVGKS 371 Query: 400 SD------GSGNHNEGSTGREGTGEGRRRDKG----IIDQGHIQL---------PRNDLD 440 D G + N T G G + DKG I+ +G+++ P + Sbjct: 372 QDKGIEIKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKTQGEVVNIEGPGQKSE 431 Query: 441 PRVL---SNTG------------------WGQTPVKQNTAWEFEESPRSERKNDNGTEAW 479 P SNTG G P N++ E + + ++DN + + Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDP---NSSDESNGNDDANSESDNNSSSR 488 Query: 480 GCAATQASNSGGKNDGSIMNST--NTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVW 537 G A+ + S +GS + S + N + N G D N+K+ SG G Sbjct: 489 GDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNG-NDDNDKSDSGKGKS 547 Query: 538 GDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGG 597 S S ++ S+ ++ S + S +++ S + + S D S+ + S+ Sbjct: 548 DSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDS--DSSDSDSSDSSDSDSSDSSNSSDSS 605 Query: 598 DWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGE 657 D +DSS + S +DS++S S +D+ +S NS+++ N ++ Sbjct: 606 DSSDSSD-----SSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660 Query: 658 TLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPS 717 + +S D++ S+ +S DSS+++ E S S Sbjct: 661 NSSNSSDSSDSSDSSDSSSSSDSSNSS---------------DSSDSSDSSNSSESSDSS 705 Query: 718 IRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVET 777 D S D S+ +N + D +N S ++ ++ ++ ++ +SN++ ++ Sbjct: 706 -------DSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758 Query: 778 PPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKP 837 + + S SS + N ++S SS S+ N + + Sbjct: 759 SDSSNSSDSSDSSD--------SSDSSDSSNSSDSNDSSNSSDSSDSS---NSSDSSNSS 807 Query: 838 PSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEE 897 SS S + + + S+ +S S GS D N S S + Sbjct: 808 DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDS 867 Query: 898 GDVWNNAASQESTSSCSS 915 D +++ S +S+ S S Sbjct: 868 SDSSDSSNSSDSSDSSDS 885 Score = 61.2 bits (147), Expect = 8e-09 Identities = 122/701 (17%), Positives = 260/701 (37%), Gaps = 73/701 (10%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSG 61 ++ S+ + + + ++ N+ ++ S S+ S+ +SN S + + S S Sbjct: 557 SSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDS-----SDSSDSS 611 Query: 62 LAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATG 121 + S D K D+ + S + S+S+ + + + N++ + + Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSS------DSSNSSNS 665 Query: 122 NPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNT 181 + SS S S + + N + + N ES++ S+ + S S+ N N+ Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSN--SSESSDSSDSSDSDSSDSSDSSNSNS 723 Query: 182 DGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSA 241 +++N +SS + ++ ++ + + + + ++ SS S S S+ Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783 Query: 242 EGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGS-GGNAWDS 300 + SN S + ++ +S+S S + D+ +S+ S N S S+ + S N+ DS Sbjct: 784 D--SNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDS 841 Query: 301 GPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGS 360 + G S ++ + + + S +SN + N+ SNS + S Sbjct: 842 SDSSDSSD---GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSS 898 Query: 361 TGWESPSVTSQNPT-------VQPGGEHMNSWAKAASSGTTASEGSSDGS--GNHNEGST 411 +S S S N + E NS + SS ++ S SSD S N ++ S Sbjct: 899 NSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSN 958 Query: 412 GREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERK 471 + + D D + D S++ + + + +S S Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018 Query: 472 NDNGTEAWGCAATQASNSGGKNDGS----------IMNSTNTSSVSGWVNAPPAAVPANT 521 +D+ + ++ +S+S +D S NS+++S S ++ ++ +++ Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1078 Query: 522 G-------WGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP 574 DS+N + S DS S+ S ++ + S +++ D S + Sbjct: 1079 SDSSESSDSSDSSNSSDSSDS--SDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136 Query: 575 PKPKSQHWGDGQRSNPAW-------------------------SAGGGDWADSSSVLGHL 609 S D S+ + S+ D +DSS Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-SSDS 1195 Query: 610 GDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKAN 650 D + D+ + S +D++ S +S + +N ++ Sbjct: 1196 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSD 1236 >gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] Length = 788 Score = 68.2 bits (165), Expect = 7e-11 Identities = 112/461 (24%), Positives = 165/461 (35%), Gaps = 59/461 (12%) Query: 1049 PSQALGGIAS-GLGMQNLNSSRQIPSGNLGMFGNSGA----AQARTMQQPPQPPVQPLNS 1103 P Q+LGG+ S G Q ++ S Q P G GM +S A A +T Q Q +Q Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165 Query: 1104 SQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQR 1163 Q + Q Q Q Q QF A+ S + Q ++ Q QLQ Q+ Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQ---------SAMQQQFQAVVQQQQQLQ---QQ 213 Query: 1164 LQIQQQMLQAQRNVSGSMRQQEQQ---VARTITNLQQQIQQHQRQLAQALLVKQPP---- 1216 Q QQ +++ ++QQ+QQ +A+ QQQ QQ Q+Q Q L QPP Sbjct: 214 QQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP 273 Query: 1217 ---PPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1273 P PPP +L + P P P + + P PL Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS---- 329 Query: 1274 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1333 + + G + P R P + P ++Q + + Sbjct: 330 ---QAQALPGQMLYTQPPLKFVRAPM------VVQQPPVQPQVQQQQTAVQTAQAAQMVA 380 Query: 1334 PPGKSSIDDSYGRYDLIQNSESPASPPV-AVPHSWSRAKSDSDKISNGSSINWPPEFHPG 1392 PG I ++ + + + P + V A+P S + SS+ PG Sbjct: 381 -PGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSPG 439 Query: 1393 VPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSH 1452 + Q++ P P PG + P N + SG S S P+ Sbjct: 440 QQVQTPQSMPPPPQPSPQPGQPSSQPNSN----------VSSG----PAPSPSSFLPSPS 485 Query: 1453 TQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLG 1493 Q S S + P+N + P+ P P T PSS SP G Sbjct: 486 PQPSQSPVTARTPQNFSVPS-PGPLNTPVNPSSV--MSPAG 523 Score = 42.7 bits (99), Expect = 0.003 Identities = 57/246 (23%), Positives = 92/246 (37%), Gaps = 44/246 (17%) Query: 1091 QQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTM 1150 Q PPQP P+ +QPS Q+P PQ Q Q L A+ + P+ M Sbjct: 300 QPPPQPQQPPVAQNQPS---QLP----PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352 Query: 1151 LNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQI----------- 1199 + Q +Q Q+ Q Q QA + V+ ++ + +A+ +++ + Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPTTAVSAIPS 412 Query: 1200 ------QQHQRQLAQALLV---------------KQPPPPPPPPHLSLHPSAGKSAMDSF 1238 +Q Q++Q+ L PPPP P P S S + S Sbjct: 413 SSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472 Query: 1239 PSHPQTPGLPDLQTKEQQS-----SPNTFAPYPLAGLNPNMNVNSMDMTGGLSVKDPSQS 1293 P+ + LP + QS +P F+ LN +N +S+ G S + Q Sbjct: 473 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQY 532 Query: 1294 QSRLPQ 1299 +L Q Sbjct: 533 LDKLKQ 538 Score = 33.1 bits (74), Expect = 2.3 Identities = 47/212 (22%), Positives = 79/212 (37%), Gaps = 43/212 (20%) Query: 1046 SALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQA----RTMQQPPQPPVQPL 1101 SA+PS ++ LG Q + Q+ +L M + Q ++M PPQP QP Sbjct: 408 SAIPSSSIP-----LGRQPM---AQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPG 459 Query: 1102 N-SSQPSLRAQVPQFLSPQV----------QAQLLQFAAKNIGL-NPALLTSPINP---- 1145 SSQP+ SP Q+ + +N + +P L +P+NP Sbjct: 460 QPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVM 519 Query: 1146 --------QHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQV-------AR 1190 + L++L QL + L+ + + + + + + R Sbjct: 520 SPAGSSQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKR 579 Query: 1191 TITNLQQQIQQHQRQLAQALLVKQPPPPPPPP 1222 Q+ + +L + V PPPPP PP Sbjct: 580 CPLKTLQKCEIALEKLKNDMAVPTPPPPPVPP 611 >gi|161016767 mucin 21 [Homo sapiens] Length = 566 Score = 68.2 bits (165), Expect = 7e-11 Identities = 120/521 (23%), Positives = 197/521 (37%), Gaps = 66/521 (12%) Query: 137 MGNQNGNPTGTLGAWGNLLPQEST--EPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSP 194 M Q GN L +G LL E+ +TSTS N S +T N+ + + SS Sbjct: 1 MKMQKGN---VLLMFGLLLHLEAATNSNETSTSANTGSSVISSGAST-ATNSGSSVTSSG 56 Query: 195 NPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG-SAEGISNSVWGLSP 253 + + + + G+++ + G+ A S S VS G S S S S Sbjct: 57 VSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSG 116 Query: 254 GNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGR 313 + AT + +S S G NS S +G+S+A + S ++ S Sbjct: 117 ASTATNSESSTPSSGASTATNSDSSTTSSGASTATNSDSSTTSSEAS------------- 163 Query: 314 GSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNP 373 + N + S + S S+ V+ N S++ +G ST S S T+ N Sbjct: 164 -TATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG-ASTATNSESRTTSNG 221 Query: 374 TVQPGGEHMNSWAKAASSGTTASEGS-----SDGSG--NHNEGSTGREGTGEGRRRDKGI 426 G NS + SSG + + S S G+G ++E ST G G + Sbjct: 222 A----GTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESST 277 Query: 427 IDQGHIQLPRNDLDPRVLSNTGWGQTPVK-QNTAWEFEESPRSERKN-----DNGTEAWG 480 + G + ++ TP NTA E S S N D+ T + G Sbjct: 278 VSSGISTVTNSE-----------SSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSG 326 Query: 481 CAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDS 540 + S S + G+ ST T+S S + A+ N+G +++ + + Sbjct: 327 ASTATNSESSTTSSGA---STATNSESS-TTSSGASTATNSGSSTTSSGTSTATNSESST 382 Query: 541 ISSTAVSTAAAAKSGHAWSGAA---NQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGG 597 +SS A STA ++S SGA+ N E + + G S+ + S+G Sbjct: 383 VSSGA-STATTSESSTTSSGASTATNSESSTVSSGASTATNSE--------SSTTSSGAN 433 Query: 598 DWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGN 638 +S S + G G +G S+ + + ++ G+ Sbjct: 434 TATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPGGS 474 Score = 58.9 bits (141), Expect = 4e-08 Identities = 94/433 (21%), Positives = 162/433 (37%), Gaps = 42/433 (9%) Query: 17 TNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDT 76 TN N + A + S+ + GA A ++GS+ GV+T + SG + S G + Sbjct: 22 TNSNETSTSA--NTGSSVISSGASTATNSGSSVTSSGVSTATISGSS--VTSNGVSIVTN 77 Query: 77 MIGDGRSQNCWGASNS-----NAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS 131 S A+NS ++GI++ N ++ + + AT + SS S Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTS-----SGASTATNSESSTPSS-- 130 Query: 132 AIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMN 191 G + + + T + GA +T +ST+ + + +A +T + N Sbjct: 131 --GASTATNSDSSTTSSGA------STATNSDSSTTSSEASTATNSESSTTSSGASTATN 182 Query: 192 SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-------SVSQVSGGSAEGI 244 S + +++ + + GA + + +NG+ S + SG S Sbjct: 183 SESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATN 242 Query: 245 SNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPA 304 S S S AT + +S S G G NS S +G S+ E S + SG Sbjct: 243 SESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPS---SGANT 299 Query: 305 GPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSD---INGKGST 361 + SG N N S + + +N + + +NS+ + ST Sbjct: 300 ATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGAST 359 Query: 362 GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG----NHNEGSTGREGTG 417 S S T+ + T ++ + AS+ TT SE S+ SG ++E ST G Sbjct: 360 ATNSGSSTTSSGTSTATNSESSTVSSGASTATT-SESSTTSSGASTATNSESSTVSSGAS 418 Query: 418 EGRRRDKGIIDQG 430 + G Sbjct: 419 TATNSESSTTSSG 431 Score = 55.1 bits (131), Expect = 6e-07 Identities = 100/429 (23%), Positives = 164/429 (38%), Gaps = 61/429 (14%) Query: 315 SGNNGVGNIHSGA---WGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVT-S 370 S N G I SGA S TS+GV S + I+G T VT S Sbjct: 30 SANTGSSVISSGASTATNSGSSVTSSGV-----------STATISGSSVTSNGVSIVTNS 78 Query: 371 QNPTVQPG-GEHMNSWAKAASSG---TTASEGSSDGSG----NHNEGSTGREGTGEGRRR 422 + T G NS SSG T SE S+ SG ++E ST G Sbjct: 79 EFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNS 138 Query: 423 DKGIIDQGHIQLPRNDL-----DPRVLSNTGWGQTPVKQNTAWEFEESPRSERKN---DN 474 D G +D + +N+ T +TA E S S R + ++ Sbjct: 139 DSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNS 198 Query: 475 GTEAWGCAATQASNSGGKND----GSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKA 530 + A+ A+NS + G+ NS ++++ SG A+T ++ Sbjct: 199 ESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSG----------ASTATNSESSTP 248 Query: 531 PSGPGVWGDSISSTAVS---TAAAAKSGHAWSG---AANQEDKSPTWGEPPKPKSQHWGD 584 SG G +S SST S TA ++S SG N E +P+ G S+ Sbjct: 249 SSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTT 308 Query: 585 GQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSG----WDADSNRSGSGWNDTTRSGNSG 640 +N A ++ + +S + + SG +++S+ + SG + T SG+S Sbjct: 309 SSGANTATNSDSSTTSSGASTATN-SESSTTSSGASTATNSESSTTSSGASTATNSGSST 367 Query: 641 WGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVK 700 + T+T N ++ T+ G + A+ + + S+ A+ ++ T G Sbjct: 368 TSSGTSTATNSESS---TVSSG--ASTATTSESSTTSSGASTATNSESSTVSSGASTATN 422 Query: 701 QKDSSEATG 709 + S+ ++G Sbjct: 423 SESSTTSSG 431 Score = 48.1 bits (113), Expect = 7e-05 Identities = 83/423 (19%), Positives = 146/423 (34%), Gaps = 56/423 (13%) Query: 499 NSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAW 558 N T+TS+ +G A A + S + G S++S VS ++ Sbjct: 25 NETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTS 84 Query: 559 SG---AANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKN 615 SG A N E + + G S+ + S+G +S S G Sbjct: 85 SGISTATNSEFSTVSSGISIATNSE--------SSTTSSGASTATNSESSTPSSGASTAT 136 Query: 616 GSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNN 675 S DS+ + SG + T S +S +T+++A+ TN E+ + A+ + + Sbjct: 137 NS----DSSTTSSGASTATNSDSS----TTSSEASTATN-SESSTTSSGASTATNSESST 187 Query: 676 VSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPS 735 VS+ A+ ++ T G + + + G T++ + Sbjct: 188 VSSRASTATNSESSTTSSGASTATNSESRTTSNG--------------AGTATNSESSTT 233 Query: 736 NYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGP 795 + T + + P + T TN+ ++TT++ + T E+ Sbjct: 234 SSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSES------------------ 275 Query: 796 GRKVSSGWGEMPNVHSKTENSWGEP---SSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPP 852 VSSG + N S T +S S ST A S+ S Sbjct: 276 -STVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSE 334 Query: 853 VAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSS 912 + +GA A ++ S SG + TS + E ++ AS +TS Sbjct: 335 SSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSE 394 Query: 913 CSS 915 S+ Sbjct: 395 SST 397 Score = 48.1 bits (113), Expect = 7e-05 Identities = 78/366 (21%), Positives = 131/366 (35%), Gaps = 46/366 (12%) Query: 493 NDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAA 552 N S S+ S+ + ++ P++ A+T ++ SG +S SST S A+ A Sbjct: 107 NSESSTTSSGASTATNSESSTPSS-GASTATNSDSSTTSSGASTATNSDSSTTSSEASTA 165 Query: 553 KSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDG 612 + S + + T E S+ + S+G +S S G G Sbjct: 166 TNSE--SSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATNSESRTTSNGAG 223 Query: 613 KKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTK-------ANPGTNW---------- 655 S S+ + + N + + +SG G +TN++ A TN Sbjct: 224 TATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGIS 283 Query: 656 ----GETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWE 711 E+ P N A+ + + S+ A+ + T G + S+ ++G Sbjct: 284 TVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSG-- 341 Query: 712 EPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNT 771 S E +S +N + T + +SST ++ +T TT+ S+T Sbjct: 342 ----ASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESST 397 Query: 772 THRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPS----TLV 827 T A T N VSSG N S T +S ++ S T Sbjct: 398 T-------SSGASTATN-----SESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSA 445 Query: 828 DNGTAA 833 +GTAA Sbjct: 446 GSGTAA 451 Score = 47.8 bits (112), Expect = 9e-05 Identities = 62/306 (20%), Positives = 128/306 (41%), Gaps = 28/306 (9%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSG 61 +T S++ + +++ + ++G + A S S ++ GAG A ++ S+ G +T ++S Sbjct: 186 STVSSRASTATNSESSTTSSGASTA-TNSESRTTSNGAGTATNSESSTTSSGASTATNSE 244 Query: 62 LAHCSVSGGDG----KMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGT 117 + S G T G G + N ++ S+ + + ++ P++ Sbjct: 245 SSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSG------AN 298 Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177 AT + SS S G N + + T + GA +T ++ST+ + + +A Sbjct: 299 TATNSESSTTSS----GANTATNSDSSTTSSGA------STATNSESSTTSSGASTATNS 348 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSV---- 233 +T + NS + ++ + + V GA + ++G+S Sbjct: 349 ESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNS 408 Query: 234 --SQVSGGSAEGISNSVWGLSPG-NPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQK 290 S VS G++ ++ S G N AT + +S S G+G + + + +S+AV + Sbjct: 409 ESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSE 468 Query: 291 EGSGGN 296 GG+ Sbjct: 469 AKPGGS 474 Score = 32.3 bits (72), Expect = 4.0 Identities = 41/205 (20%), Positives = 75/205 (36%), Gaps = 21/205 (10%) Query: 754 SSTTTNTTTTTTTT---------TSNTTHRVETPPPHQAGTQLNRSPLL--GPGRKVSSG 802 +ST TN+ ++TT++ +S T+ T ++ T +R+ SSG Sbjct: 147 ASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSG 206 Query: 803 WGEMPNVHSKTENSW------GEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFG 856 N S+T ++ E S+ S+ T + PSSG+G + + G Sbjct: 207 ASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSG 266 Query: 857 RAGAPVAASAL----CKPASKSMQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSS 912 A + S+ + S SG + S S + N+ S ++S Sbjct: 267 AGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSG 326 Query: 913 CSSWGNAPKKGLQKGMKTSGKQDEA 937 S+ N+ G T+ + + Sbjct: 327 ASTATNSESSTTSSGASTATNSESS 351 >gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] Length = 1230 Score = 67.4 bits (163), Expect = 1e-10 Identities = 100/455 (21%), Positives = 166/455 (36%), Gaps = 79/455 (17%) Query: 445 SNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTS 504 S +GW + S S N A+ S+SG + + + +T Sbjct: 16 SGSGWASSSA----------SGASTPSNSGWASPSASGASIPSDSGWASPSA--SGASTP 63 Query: 505 SVSGWVN--APPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAA 562 S SGW + A A++P+++GW + S P G + S +A + + SG A + Sbjct: 64 SNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWA-SPSASGASIPSDSGWASPSVS 122 Query: 563 NQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDAD 622 S W P G S+ W++ WA +SS G S + Sbjct: 123 GASIPSAFWASPSAS-----GASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASC 177 Query: 623 SNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGA 682 ++ S SG + +SGW + + +P T+W + WAS P D+ ++ A Sbjct: 178 ASSSASG---ASTPSDSGWASPSVFWVSPSTSWASS---PSDFGWASTPSDSGWAS-SSA 230 Query: 683 ASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPP--SIRRKMEIDDGTSAWGDPSNYNNK 740 + + + +G +S +GW PS S S W S Sbjct: 231 SCISPSASG----------ASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSS----- 275 Query: 741 TVNMWDR----NNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRS-----P 791 WD + V S++ +++ + + S++ + P + L+ S Sbjct: 276 --ASWDSITSDSGWVCPSASWASSSASWASAPSDSG---SSSPSVSRASTLSVSGWASFS 330 Query: 792 LLGPGRKVSSGW--GEMPNVHSKTENSWGEPSS--PSTLVDNG----TAAWGKPPSSG-- 841 G SGW V + +++ W PS+ ST D+G +A+W P +SG Sbjct: 331 ASGASAPSDSGWTSHSASGVSTTSDSGWASPSASGASTSSDSGWASPSASWASPSASGAS 390 Query: 842 ----SGWGDHPAEPPVAFGRA--GAPVAASALCKP 870 SGW P A G + AP C P Sbjct: 391 TPSDSGWAS-----PSASGASMPSAPSLCPGSCFP 420 Score = 67.0 bits (162), Expect = 1e-10 Identities = 91/442 (20%), Positives = 158/442 (35%), Gaps = 63/442 (14%) Query: 214 MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGF---SQGNG 270 M + + G+ +GS + S A SNS W + A+ S+SG+ S Sbjct: 1 MASFLFSRASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGA 60 Query: 271 DTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGH 330 T +++ A + S +++ + SG + + + P W S +G W Sbjct: 61 STPSNSGWASFSASWASIPSD-SGWASPSASWASTPSDSGWASPSA-SGASIPSDSGWAS 118 Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAAS 390 PS S ++ + W P S S + +GW SPS + + + G WA ++ Sbjct: 119 PSVSGASIPSAFWASP----SASGASTPSDSGWASPSASWASTSSDSG------WASPSA 168 Query: 391 SGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWG 450 S T+ S + S +G D G + + S+ GW Sbjct: 169 SWTSPSASCASSS-----------ASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWA 217 Query: 451 QTPVKQNTAWEFEE----SPRSERKNDNGTEAWGC-----AATQASNSGGKNDGSIMNST 501 TP ++ W SP + + + W +T S + +D +S+ Sbjct: 218 STP--SDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSS 275 Query: 502 ----NTSSVSGWVNAPPAAVPANTGW----GDSNNKAPS-------GPGVWGDSISSTAV 546 + +S SGWV + ++ W DS + +PS W +S A Sbjct: 276 ASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGAS 335 Query: 547 STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVL 606 + + + + H+ SG + D W P G S+ W++ WA S+ Sbjct: 336 APSDSGWTSHSASGVSTTSDSG--WASPSAS-----GASTSSDSGWASPSASWASPSA-- 386 Query: 607 GHLGDGKKNGSGWDADSNRSGS 628 G + SGW + S S Sbjct: 387 --SGASTPSDSGWASPSASGAS 406 Score = 64.3 bits (155), Expect = 1e-09 Identities = 104/458 (22%), Positives = 164/458 (35%), Gaps = 78/458 (17%) Query: 482 AATQASNSGGKNDGSIMNSTNTSSVSGWVN--APPAAVPANTGWGDSNNKAPSGPGVWGD 539 A+ ++ SG S + +T S SGW + A A++P+++GW +PS G Sbjct: 9 ASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWA-----SPSASGASTP 63 Query: 540 SISSTAVSTA--AAAKSGHAWSGAANQEDKSPT---WGEPPKPKSQHWGDGQRSNPAWSA 594 S S A +A A+ S W+ + +P+ W P + D ++P+ S Sbjct: 64 SNSGWASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSG 123 Query: 595 G---GGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANP 651 WA S+ G + SGW + S + W T S +SGW + + + +P Sbjct: 124 ASIPSAFWASPSA----SGASTPSDSGWASPS----ASWAST--SSDSGWASPSASWTSP 173 Query: 652 GTNWGETLKPGPQQNWASKPQDNNVSNWGGAASV-KQTGTGWIGGPVPVKQKDSSEATGW 710 + + G AS P D S W + T W P + +GW Sbjct: 174 SASCASSSASG-----ASTPSD---SGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGW 225 Query: 711 EEPSPPSIRRKME--IDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTT 768 S I S W P S + +T+T+ +T Sbjct: 226 ASSSASCISPSASGASTSSDSGWASP--------------------SASWVSTSTSRAST 265 Query: 769 SNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVD 828 S+ + + + T + S + P +S + S + +S S STL Sbjct: 266 SSDSGWASSSASWDSIT--SDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSV 323 Query: 829 NGTAAW---GKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDE 885 +G A++ G S SGW H A +G AS AS S GW S Sbjct: 324 SGWASFSASGASAPSDSGWTSHSASGVSTTSDSG---WASPSASGASTSSDSGWAS---- 376 Query: 886 MNLSTSQWEDEEGDVWNNAASQESTSSCSSWGNAPKKG 923 ++ W + +AS ST S S W + G Sbjct: 377 ---PSASWA-------SPSASGASTPSDSGWASPSASG 404 Score = 49.7 bits (117), Expect = 2e-05 Identities = 86/403 (21%), Positives = 156/403 (38%), Gaps = 52/403 (12%) Query: 20 NNGTNGALVQSPSNQSALGAGGAN----SNGSAARVWGVATGSSSGLAHCSVSGGDGKMD 75 ++ +GA S S ++ A GA+ S ++ G +T S+SG A S S D Sbjct: 22 SSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWASFSASWASIPSD 81 Query: 76 TMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPV-LGHEGTVATGN--PSSICSPVSA 132 + G W ++ S++G +P+A+ A+ P G +G PS+ + SA Sbjct: 82 S--GWASPSASWASTPSDSGW---ASPSASGASIPSDSGWASPSVSGASIPSAFWASPSA 136 Query: 133 IGQNMGNQNG--------NPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGP 184 G + + +G T + W + ++ + S + S ++ P + P Sbjct: 137 SGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSASGASTPSDSGWASP 196 Query: 185 N-----NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGG 239 + + SSP+ T W A + I P A+G+S S SG Sbjct: 197 SVFWVSPSTSWASSPSDFGWASTPSDSGW--ASSSASCISP------SASGASTSSDSGW 248 Query: 240 SAEGISNSVWGLSPGNPATGNSNSGF--SQGNGDTVNSALSAKQNGSSSAVQKEGSGGNA 297 ++ S W + + A+ +S+SG+ S + D++ S +G S + Sbjct: 249 ASPSAS---WVSTSTSRASTSSDSGWASSSASWDSITS-----DSGWVCPSASWASSSAS 300 Query: 298 WDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDING 357 W S P GS + V + + + +++G + HS S ++ Sbjct: 301 WASAPSDS--------GSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVST 352 Query: 358 KGSTGWESPSVTSQNPTVQPG-GEHMNSWAKAASSGTTASEGS 399 +GW SPS + + + G SWA ++SG + S Sbjct: 353 TSDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSDS 395 Score = 37.4 bits (85), Expect = 0.12 Identities = 59/246 (23%), Positives = 88/246 (35%), Gaps = 23/246 (9%) Query: 1446 SSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWGASPLGWTSSYSSGSAWS 1505 +S P+ AS S W P S A + G + S W +S S +SG++ S Sbjct: 185 ASTPSDSGWASPS-VFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGASTS 243 Query: 1506 TDT--SGRTSSWLVLRNLTPQIDGSTLRTLCLQHGPLITFHLNLTQGNAVVRYSSKEEAA 1563 +D+ + ++SW+ + IT +A SS A+ Sbjct: 244 SDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASWAS 303 Query: 1564 KAQKSLHMCVLGNTTILAEFAGEEEVN---RFLAQGQALPPTSSWQSSSASSQPRLSAAG 1620 S G+++ A V+ F A G + P S W S SAS S +G Sbjct: 304 APSDS------GSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSDSG 357 Query: 1621 ----SSHGLVRSDAGHWNAPCLGGKGSSELLWGGVPQYSSSLWGPPSADDSRVIGSPTPL 1676 S+ G S W +P S G S S W PSA + + +P Sbjct: 358 WASPSASGASTSSDSGWASPSASWASPSA---SGASTPSDSGWASPSASGASMPSAP--- 411 Query: 1677 TTLLPG 1682 +L PG Sbjct: 412 -SLCPG 416 Score = 34.3 bits (77), Expect = 1.1 Identities = 28/84 (33%), Positives = 35/84 (41%), Gaps = 16/84 (19%) Query: 1594 AQGQALPPTSSWQSSSASSQPRLSAAG-----SSHGLVRSDAGHWNAPCLGGK------- 1641 A G + P S W SSSAS S +G +S + SD+G W +P G Sbjct: 9 ASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSG-WASPSASGASTPSNSG 67 Query: 1642 -GSSELLWGGVPQYSSSLWGPPSA 1664 S W +P S S W PSA Sbjct: 68 WASFSASWASIP--SDSGWASPSA 89 Score = 32.0 bits (71), Expect = 5.2 Identities = 57/262 (21%), Positives = 95/262 (36%), Gaps = 36/262 (13%) Query: 53 GVATGSSSGLAHCSV-------SGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNAN 105 G +T S SG A SV S D S + W +S+++ ++P+A+ Sbjct: 184 GASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASC-----ISPSAS 238 Query: 106 PAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTS 165 A+ T + S SP SA + + + G W + S + TS Sbjct: 239 GAS-----------TSSDSGWASP-SASWVSTSTSRASTSSDSG-WAS--SSASWDSITS 283 Query: 166 TSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGL 225 S V SA + + + + SS ++ T + W GA Sbjct: 284 DSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGA-------SA 336 Query: 226 PGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSS 285 P +G + SG S S+S W + A+ +S+SG++ + + + S S Sbjct: 337 PSDSGWTSHSASGVSTT--SDSGWASPSASGASTSSDSGWASPSASWASPSASGASTPSD 394 Query: 286 SAVQKEGSGGNAWDSGPPAGPG 307 S + G + S P PG Sbjct: 395 SGWASPSASGASMPSAPSLCPG 416 >gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] Length = 748 Score = 65.1 bits (157), Expect = 6e-10 Identities = 91/391 (23%), Positives = 138/391 (35%), Gaps = 38/391 (9%) Query: 1049 PSQALGGIAS-GLGMQNLNSSRQIPSGNLGMFGNSGA----AQARTMQQPPQPPVQPLNS 1103 P Q+LGG+ S G Q ++ S Q P G GM +S A A +T Q Q +Q Sbjct: 106 PGQSLGGMGSLGAMGQPMSLSGQPPPGTSGMAPHSMAVVSTATPQTQLQLQQVALQQQQQ 165 Query: 1104 SQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQLQLAYQR 1163 Q + Q Q Q Q QF A+ S + Q ++ Q QLQ Q+ Sbjct: 166 QQQFQQQQQAALQQQQQQQQQQQFQAQQ---------SAMQQQFQAVVQQQQQLQ---QQ 213 Query: 1164 LQIQQQMLQAQRNVSGSMRQQEQQ---VARTITNLQQQIQQHQRQLAQALLVKQPP---- 1216 Q QQ +++ ++QQ+QQ +A+ QQQ QQ Q+Q Q L QPP Sbjct: 214 QQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP 273 Query: 1217 ---PPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1273 P PPP +L + P P P + + P PL Sbjct: 274 PMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVS---- 329 Query: 1274 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1333 + + G + P R P + Q + G+ + Sbjct: 330 ---QAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVS 386 Query: 1334 PPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNGSSINWPPEFHPGV 1393 + S +Q +S PP P + + +S+G + + P F P Sbjct: 387 QSSLPML-SSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPS-PSSFLPSP 444 Query: 1394 PWKGLQNIDPENDPDVTPGSVPTGPTINTTI 1424 + Q+ P SVP+ +NT + Sbjct: 445 SPQPSQSPVTARTPQ--NFSVPSPGPLNTPV 473 Score = 50.1 bits (118), Expect = 2e-05 Identities = 56/215 (26%), Positives = 85/215 (39%), Gaps = 22/215 (10%) Query: 1091 QQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTM 1150 Q PPQP P+ +QPS Q+P PQ Q Q L A+ + P+ M Sbjct: 300 QPPPQPQQPPVAQNQPS---QLP----PQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPM 352 Query: 1151 LNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTIT-NLQQQIQQHQRQLAQA 1209 + Q +Q Q+ Q Q QA + V+ ++ + + + + QQ+Q Q Sbjct: 353 VVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQ------ 406 Query: 1210 LLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQS-----SPNTFAP 1264 PPPP P P S S + S P+ + LP + QS +P F+ Sbjct: 407 ---SMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSV 463 Query: 1265 YPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQ 1299 LN +N +S+ G S + Q +L Q Sbjct: 464 PSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQ 498 Score = 31.2 bits (69), Expect = 8.9 Identities = 40/188 (21%), Positives = 68/188 (36%), Gaps = 35/188 (18%) Query: 1070 QIPSGNLGMFGNSGAAQA----RTMQQPPQPPVQPLN-SSQPSLRAQVPQFLSPQV---- 1120 Q+ +L M + Q ++M PPQP QP SSQP+ SP Sbjct: 384 QVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPS 443 Query: 1121 ------QAQLLQFAAKNIGL-NPALLTSPINP------------QHMTMLNQLYQLQLAY 1161 Q+ + +N + +P L +P+NP + L++L QL Sbjct: 444 PSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQQYLDKLKQLSKYI 503 Query: 1162 QRLQIQQQMLQAQRNVSGSMRQQEQQV-------ARTITNLQQQIQQHQRQLAQALLVKQ 1214 + L+ + + + + + + R Q+ + +L + V Sbjct: 504 EPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCPLKTLQKCEIALEKLKNDMAVPT 563 Query: 1215 PPPPPPPP 1222 PPPPP PP Sbjct: 564 PPPPPVPP 571 >gi|186928827 dermokine isoform 5 precursor [Homo sapiens] Length = 398 Score = 60.1 bits (144), Expect = 2e-08 Identities = 67/233 (28%), Positives = 89/233 (38%), Gaps = 24/233 (10%) Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281 QG+PG NG+ + SGG GI S GL G GN G +G NSA S Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186 Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337 N + + G+GG G A PG + + N G N G S ++ Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246 Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397 G + G + + + NG S G S S + + GG NS SG+ +S Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 398 GSSDGSGNHNEGST-------------GREGTGEGRRRDKGIIDQGHIQLPRN 437 GSS GS + N G + G E G G +G QG RN Sbjct: 307 GSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRN 359 Score = 52.8 bits (125), Expect = 3e-06 Identities = 94/387 (24%), Positives = 130/387 (33%), Gaps = 61/387 (15%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60 +TG+ G GH G AL + AGGA S S A G + Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117 G+ G + +G+ N A + +A +W V GH G Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141 Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177 T I +G G GNP G W + P S SF PQ Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMA-VGMGAIIPPHLQGLPGANGS----- 231 N P N N A+ G + + G PP G++ S Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249 Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKE 291 S S SG + G +N+ G S G ++G+S+ G S G SS Sbjct: 250 SQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSS----------------GGSSGGSSG 291 Query: 292 GSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHS 351 SGG+ DSG + +WG +G++ GN H G+ G NG KP N+ Sbjct: 292 NSGGSRGDSGSES-----SWGSSTGSSS-GN-HGGSGG------GNGHKPGCEKPGNEAR 338 Query: 352 NSDINGKGSTGWESPSVTSQNPTVQPG 378 S +G + S +N PG Sbjct: 339 GSGESGIQGFRGQGVSSNMRNSETSPG 365 Score = 48.1 bits (113), Expect = 7e-05 Identities = 53/233 (22%), Positives = 86/233 (36%), Gaps = 33/233 (14%) Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568 WV+ P + G AP G G G + + A A+ G+ A+NQ + Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229 Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628 +NP S GG ++S G +GS D ++ S Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270 Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688 G + + SG S G+S + N G + G++ G + +W S G++S Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318 Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKT 741 G+G G P +K +EA G E R + + ++ P +N T Sbjct: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMRNSETSPGMFNFDT 371 Score = 41.6 bits (96), Expect = 0.007 Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%) Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281 QG A G+ V QV G G+A+ + N V A GN+ + D + A + Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129 Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341 GS V G G AW++ G GI G G G GN G G P V+G Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175 Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398 G N GS G NP P G+ N + G A G Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216 Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457 S + N NEG T +G G SN+G G + Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254 Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517 + S N+NG+ + G ++ S+SGG + GS S+ S S + ++ Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 518 PANTGWGDSNNKAPSGPG 535 ++TG S N SG G Sbjct: 307 GSSTG-SSSGNHGGSGGG 323 Score = 37.7 bits (86), Expect = 0.095 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 802 GWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAP 861 G G PN + T+ + +P S N PP SGSG G + G +G+ Sbjct: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG-----GGSGSQ 251 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQESTSSCSSWGNA 919 +S ++ G SGG S+ S G N+ S+ + S SSWG++ Sbjct: 252 SGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309 >gi|186928829 dermokine isoform 4 precursor [Homo sapiens] Length = 386 Score = 59.7 bits (143), Expect = 2e-08 Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%) Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281 QG+PG NG+ + SGG GI S GL G GN G +G NSA S Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186 Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337 N + + G+GG G A PG + + N G N G S ++ Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246 Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397 G + G + + + NG S G S S + + GG NS SG+ +S Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 398 GSSDGSGNHNEGSTG 412 GSS GS + N G +G Sbjct: 307 GSSTGSSSGNHGGSG 321 Score = 52.8 bits (125), Expect = 3e-06 Identities = 91/390 (23%), Positives = 122/390 (31%), Gaps = 79/390 (20%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60 +TG+ G GH G AL + AGGA S S A G + Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117 G+ G + +G+ N A + +A +W V GH G Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141 Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177 T I +G G GNP G W + P S SF PQ Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVS 237 N P N N GA+ P + +N + Sbjct: 190 GAPWGQGGNGGPPNFGTNT-----------------QGAVAQPGYGSVRASNQN------ 226 Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQG--NGDTVNSALSAKQNGSSSAVQKEGSGG 295 EG +N P G+SNSG G +G + + + NGSSS GS Sbjct: 227 ----EGCTNP----PPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278 Query: 296 NAWDSGPPAGPGILAWGRGSGNNGVGNIHSG---AWGHPSRSTSNGVNGEWG----KPPN 348 G G SGN+G SG +WG + S+S G G KP Sbjct: 279 GGSSGGSSGG--------SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330 Query: 349 QHSNSDINGKGSTGWESPSVTSQNPTVQPG 378 + ++ G G +G QN PG Sbjct: 331 EKPGNEARGSGESG-------IQNSETSPG 353 Score = 47.8 bits (112), Expect = 9e-05 Identities = 48/201 (23%), Positives = 76/201 (37%), Gaps = 33/201 (16%) Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568 WV+ P + G AP G G G + + A A+ G+ A+NQ + Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229 Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628 +NP S GG ++S G +GS D ++ S Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270 Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688 G + + SG S G+S + N G + G++ G + +W S G++S Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318 Query: 689 GTGWIGGPVPVKQKDSSEATG 709 G+G G P +K +EA G Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339 Score = 41.6 bits (96), Expect = 0.007 Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%) Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281 QG A G+ V QV G G+A+ + N V A GN+ + D + A + Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129 Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341 GS V G G AW++ G GI G G G GN G G P V+G Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175 Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398 G N GS G NP P G+ N + G A G Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216 Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457 S + N NEG T +G G SN+G G + Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254 Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517 + S N+NG+ + G ++ S+SGG + GS S+ S S + ++ Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 518 PANTGWGDSNNKAPSGPG 535 ++TG S N SG G Sbjct: 307 GSSTG-SSSGNHGGSGGG 323 Score = 37.7 bits (86), Expect = 0.095 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 802 GWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAP 861 G G PN + T+ + +P S N PP SGSG G + G +G+ Sbjct: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG-----GGSGSQ 251 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQESTSSCSSWGNA 919 +S ++ G SGG S+ S G N+ S+ + S SSWG++ Sbjct: 252 SGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309 >gi|186928825 dermokine isoform 3 precursor [Homo sapiens] Length = 416 Score = 59.7 bits (143), Expect = 2e-08 Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%) Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281 QG+PG NG+ + SGG GI S GL G GN G +G NSA S Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186 Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337 N + + G+GG G A PG + + N G N G S ++ Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246 Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397 G + G + + + NG S G S S + + GG NS SG+ +S Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 398 GSSDGSGNHNEGSTG 412 GSS GS + N G +G Sbjct: 307 GSSTGSSSGNHGGSG 321 Score = 52.8 bits (125), Expect = 3e-06 Identities = 94/372 (25%), Positives = 128/372 (34%), Gaps = 41/372 (11%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60 +TG+ G GH G AL + AGGA S S A G + Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117 G+ G + +G+ N A + +A +W V GH G Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141 Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177 T I +G G GNP G W + P S SF PQ Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMA-VGMGAIIPPHLQGLPGANGS----- 231 N P N N A+ G + + G PP G++ S Sbjct: 190 GAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG 249 Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGN--GDTVNSALSAKQNGSSSA-- 287 S S SG + G +N+ G S G ++G+S+ G S G+ G + NS S +GS S+ Sbjct: 250 SQSGSSGSGSNGDNNN--GSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWG 307 Query: 288 VQKEGSGGNAWDSGPPAG--PGILAWG---RGSGNNGVGNIHSGAWGHPSRSTSNGVNGE 342 S GN SG G PG G RGSG +G+ R S N Sbjct: 308 SSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRL 367 Query: 343 WGKPPNQHSNSD 354 G + + NS+ Sbjct: 368 LGGSGDNYRNSE 379 Score = 48.9 bits (115), Expect = 4e-05 Identities = 55/239 (23%), Positives = 86/239 (35%), Gaps = 41/239 (17%) Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568 WV+ P + G AP G G G + + A A+ G+ A+NQ + Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229 Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628 +NP S GG ++S G +GS D ++ S Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270 Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688 G + + SG S G+S + N G + G++ G + +W S G++S Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318 Query: 689 GTGWIGGPVPVKQKDSSEATGWEEPSPPSIR--------RKMEIDDGTSAWGDPSNYNN 739 G+G G P +K +EA G E R R++ + G NY N Sbjct: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRN 377 Score = 41.6 bits (96), Expect = 0.007 Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%) Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281 QG A G+ V QV G G+A+ + N V A GN+ + D + A + Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129 Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341 GS V G G AW++ G GI G G G GN G G P V+G Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175 Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398 G N GS G NP P G+ N + G A G Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216 Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457 S + N NEG T +G G SN+G G + Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254 Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517 + S N+NG+ + G ++ S+SGG + GS S+ S S + ++ Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 518 PANTGWGDSNNKAPSGPG 535 ++TG S N SG G Sbjct: 307 GSSTG-SSSGNHGGSGGG 323 Score = 37.7 bits (86), Expect = 0.095 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 802 GWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAP 861 G G PN + T+ + +P S N PP SGSG G + G +G+ Sbjct: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG-----GGSGSQ 251 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQESTSSCSSWGNA 919 +S ++ G SGG S+ S G N+ S+ + S SSWG++ Sbjct: 252 SGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309 >gi|33504489 dermokine isoform 2 precursor [Homo sapiens] Length = 476 Score = 59.7 bits (143), Expect = 2e-08 Identities = 59/195 (30%), Positives = 80/195 (41%), Gaps = 11/195 (5%) Query: 223 QGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNS-GFSQGNGDTVNSALSAKQ 281 QG+PG NG+ + SGG GI S GL G GN G +G NSA S Sbjct: 133 QGVPGHNGAW--ETSGG--HGIFGSQGGL--GGQGQGNPGGLGTPWVHGYPGNSAGSFGM 186 Query: 282 NGSSSAVQKEGSGG----NAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337 N + + G+GG G A PG + + N G N G S ++ Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246 Query: 338 GVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASE 397 G + G + + + NG S G S S + + GG NS SG+ +S Sbjct: 247 GSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 398 GSSDGSGNHNEGSTG 412 GSS GS + N G +G Sbjct: 307 GSSTGSSSGNHGGSG 321 Score = 52.8 bits (125), Expect = 3e-06 Identities = 91/390 (23%), Positives = 122/390 (31%), Gaps = 79/390 (20%) Query: 2 ATGSAQGNFTGHTKKTNGNNGTNGALVQSPSNQSALGAGGA-NSNGSAARVWGVATGSSS 60 +TG+ G GH G AL + AGGA S S A G + Sbjct: 30 STGTNIGEALGH--------GLGDALSEGVGKAIGKEAGGAAGSKVSEALGQGTREAVGT 81 Query: 61 GLAHCSVSGGDGKMDTMIGDGRSQ--NCWGASNSNAGINLNLNPNANPAAWP-VLGHEGT 117 G+ G + +G+ N A + +A +W V GH G Sbjct: 82 GVRQVPGFGAADALGNRVGEAAHALGNTGHEIGRQAEDVIRHGADAVRGSWQGVPGHNGA 141 Query: 118 VATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQ 177 T I +G G GNP G W + P S SF PQ Sbjct: 142 WETSGGHGIFGSQGGLG---GQGQGNPGGLGTPWVHGYPGNSAG---------SFGMNPQ 189 Query: 178 NLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVS 237 N P N N GA+ P + +N + Sbjct: 190 GAPWGQGGNGGPPNFGTNT-----------------QGAVAQPGYGSVRASNQN------ 226 Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQG--NGDTVNSALSAKQNGSSSAVQKEGSGG 295 EG +N P G+SNSG G +G + + + NGSSS GS Sbjct: 227 ----EGCTNP----PPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSS 278 Query: 296 NAWDSGPPAGPGILAWGRGSGNNGVGNIHSG---AWGHPSRSTSNGVNGEWG----KPPN 348 G G SGN+G SG +WG + S+S G G KP Sbjct: 279 GGSSGGSSGG--------SSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGC 330 Query: 349 QHSNSDINGKGSTGWESPSVTSQNPTVQPG 378 + ++ G G +G QN PG Sbjct: 331 EKPGNEARGSGESG-------IQNSETSPG 353 Score = 47.8 bits (112), Expect = 9e-05 Identities = 48/201 (23%), Positives = 76/201 (37%), Gaps = 33/201 (16%) Query: 509 WVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKS 568 WV+ P + G AP G G G + + A A+ G+ A+NQ + Sbjct: 172 WVHGYPGNSAGSFGMNPQG--APWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGC 229 Query: 569 PTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGS 628 +NP S GG ++S G +GS D ++ S Sbjct: 230 -------------------TNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSG 270 Query: 629 GWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQT 688 G + + SG S G+S + N G + G++ G + +W S G++S Sbjct: 271 GSSSGSSSGGSSGGSSGGSSGNSGGSRGDS---GSESSWGSST---------GSSSGNHG 318 Query: 689 GTGWIGGPVPVKQKDSSEATG 709 G+G G P +K +EA G Sbjct: 319 GSGGGNGHKPGCEKPGNEARG 339 Score = 41.6 bits (96), Expect = 0.007 Identities = 83/318 (26%), Positives = 114/318 (35%), Gaps = 72/318 (22%) Query: 223 QGLPGANGSSVSQVSG-GSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQ 281 QG A G+ V QV G G+A+ + N V A GN+ + D + A + Sbjct: 73 QGTREAVGTGVRQVPGFGAADALGNRV---GEAAHALGNTGHEIGRQAEDVIRHGADAVR 129 Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341 GS V G G AW++ G GI G G G GN G G P V+G Sbjct: 130 -GSWQGVP--GHNG-AWETS--GGHGIFGSQGGLGGQGQGN--PGGLGTP------WVHG 175 Query: 342 EWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAK---AASSGTTASEG 398 G N GS G NP P G+ N + G A G Sbjct: 176 YPG-----------NSAGSFG--------MNPQGAPWGQGGNGGPPNFGTNTQGAVAQPG 216 Query: 399 -SSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQN 457 S + N NEG T +G G SN+G G + Sbjct: 217 YGSVRASNQNEGCTNPPPSGSGGGS----------------------SNSGGGSGSQSGS 254 Query: 458 TAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAV 517 + S N+NG+ + G ++ S+SGG + GS S+ S S + ++ Sbjct: 255 SG------SGSNGDNNNGSSSGG--SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSW 306 Query: 518 PANTGWGDSNNKAPSGPG 535 ++TG S N SG G Sbjct: 307 GSSTG-SSSGNHGGSGGG 323 Score = 37.7 bits (86), Expect = 0.095 Identities = 32/120 (26%), Positives = 48/120 (40%), Gaps = 9/120 (7%) Query: 802 GWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAP 861 G G PN + T+ + +P S N PP SGSG G + G +G+ Sbjct: 197 GNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSG-----GGSGSQ 251 Query: 862 VAASALCKPASKSMQEGWGSGGDEMNLST--SQWEDEEGDVWNNAASQESTSSCSSWGNA 919 +S ++ G SGG S+ S G N+ S+ + S SSWG++ Sbjct: 252 SGSSG--SGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS 309 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 58.9 bits (141), Expect = 4e-08 Identities = 71/289 (24%), Positives = 113/289 (39%), Gaps = 32/289 (11%) Query: 984 KRGLGVTDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPL 1043 ++G GV + + KP G PP S + G LV++ +P P + P Sbjct: 3758 QQGPGVQTNQALGPKPQGLMPPSSHQ------------GLLVQQLSPQPPQGPQGMLGPA 3805 Query: 1044 SHSALPSQALGGIASG-------LGMQNLNSSRQIPSGNLGMFGN---SGAAQARTMQQP 1093 + L Q G + + + SS Q+ G+ G+ + Q + Q Sbjct: 3806 QVAVLQQQHPGALGPQGPHRQVLMTQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQ 3865 Query: 1094 PQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQ 1153 Q + L+ Q SL + Q P++ AQ + + + Q L Q Sbjct: 3866 QQGSMAGLSHLQQSLMSHSGQ---PKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQ 3922 Query: 1154 LYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVK 1213 QLQ Q+LQ QQQ Q Q+ ++QQ+QQ+ + QQQ QQ Q+Q LL + Sbjct: 3923 QQQLQ--QQQLQQQQQQQQLQQQQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQ 3980 Query: 1214 Q----PPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSS 1258 P ++L P + F S P G L T ++Q++ Sbjct: 3981 SRTLLSPQQQQQQQVALGPGMPAKPLQHF-SSPGALGPTLLLTGKEQNT 4028 Score = 37.7 bits (86), Expect = 0.095 Identities = 72/294 (24%), Positives = 103/294 (35%), Gaps = 50/294 (17%) Query: 1217 PPPPPPHLS-------LHPSAGKSAMDSFPSHP----QTPGLPDL--QTKEQQSSPNTFA 1263 P P PHLS L P + + + P P Q G P L Q +E SP T Sbjct: 754 PRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEG-PHLSPQPEELHLSPQTEE 812 Query: 1264 PYPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKH 1323 P+ L+ + ++ LS + S P+ +H + P + E+ P + Sbjct: 813 PH-LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEP 871 Query: 1324 GAIPGGLSIG---PPGKSSIDDSYGRYDLIQNSESPASP-PVAVPHSWSRAKSDSDKISN 1379 G P + PPG+ S+ G L + E P SP P +P S S S S Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLS----- 926 Query: 1380 GSSINWPPEFHPGVPWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLS 1439 P+ P P + P P +T + P + + G K Sbjct: 927 -------PQLMPPDP------LPPPLSPIITAAAPP-------ALSPLGELEYPFGAKGD 966 Query: 1440 DIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSSTWG-ASPL 1492 + + P T S E N T P PP + P P S G ASP+ Sbjct: 967 SDPESPLAAPILETPISPPPE-----ANCTDPEPVPPMILPPSPGSPVGPASPI 1015 Score = 37.4 bits (85), Expect = 0.12 Identities = 38/117 (32%), Positives = 48/117 (41%), Gaps = 14/117 (11%) Query: 1151 LNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQAL 1210 L Q QLQL QR+Q+ Q++ Q Q+ +QQ+Q + + QQQ Q Q QAL Sbjct: 3715 LLQERQLQLQQQRMQLAQKLQQQQQQ-----QQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769 Query: 1211 LVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTP-GL--PDLQTKEQQSSPNTFAP 1264 K PP H G P PQ P G+ P QQ P P Sbjct: 3770 GPKPQGLMPPSSH------QGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGP 3820 Score = 35.4 bits (80), Expect = 0.47 Identities = 80/378 (21%), Positives = 122/378 (32%), Gaps = 68/378 (17%) Query: 990 TDHNGMAAKPLGCRPPISKESSVDRPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALP 1049 T MA +P +P +S +S + L+ +P P P S L+ PL LP Sbjct: 4053 TTPESMATEPGEVKPSLSGDSQL-----------LLVQPQPQPQPSSLQLQPPLR---LP 4098 Query: 1050 SQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTM------------QQPPQPP 1097 Q Q ++ G+ G G+ +++A ++ QP Sbjct: 4099 GQQ---------QQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMT 4149 Query: 1098 VQPLNSSQPSLRAQVPQFLSPQVQ--AQLLQFAA--KNIGLNPALLTSPINPQHMTMLNQ 1153 L QP L + PQ +LQ +G+ P + Q + N Sbjct: 4150 QNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNP 4209 Query: 1154 LYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQ-QVARTITNLQQQIQQHQRQLA----- 1207 + Q+ Q+Q ++Q Q S ++RQ Q T T+ Q + Q QL Sbjct: 4210 QLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGP 4269 Query: 1208 ---QALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAP 1264 + P P PP L P A + P HP P + K P+ + Sbjct: 4270 QTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQ 4329 Query: 1265 YPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLPQ------------WTHPNSMDNLPSA 1312 P P + + G P + Q W P DNL Sbjct: 4330 LPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPP---DNLAET 4386 Query: 1313 ASPLEQNPSKHGAIPGGL 1330 Q P + +PG L Sbjct: 4387 -----QKPEQSSLVPGHL 4399 Score = 34.3 bits (77), Expect = 1.1 Identities = 73/296 (24%), Positives = 93/296 (31%), Gaps = 66/296 (22%) Query: 1207 AQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHP--QTPGLPDLQTKEQQSSPNTFAP 1264 AQ L +P PPPP +L P S PS P + P P Q+ Q SP T P Sbjct: 2379 AQPPLTPRPQPPPPESCCALPPR-------SLPSDPFSRVPASPQSQSSSQ--SPLTPRP 2429 Query: 1265 YPLAGLNPNMNVNSMDMTGGLSVKDPSQSQSRLP-QWTHPNSMDNLPSA---ASPLEQNP 1320 P+ S + PS+ QSR P H P A L Sbjct: 2430 LSAEAFCPSPVTPRFQSPDPYS-RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTS 2488 Query: 1321 SKHGAIPGGLSIGPPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSRAKSDSDKISNG 1380 G P L GP G E A P P ++ R+ + Sbjct: 2489 LGAGGFPAALPAGPAG-----------------ELHAKVPSGQPPNFVRSPGTGAFVGTP 2531 Query: 1381 SSINW-------PPEFHPGVPWKGL---QNIDPENDPDVTPGSVPTGPTINTTIQDVNRY 1430 S + + P P VP GL I+ P T G + N T+ N + Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGK---PQSTNYTVATGNFH 2588 Query: 1431 LLKSGGKLSDIKSTWSSGPTSHTQASLSHELWKVPRNSTAPTRPPPGLTNPKPSST 1486 SG L SSG T + +P RPP L P P + Sbjct: 2589 --PSGSPLGP-----SSGSTGESY-------------GLSPLRPPSVLPPPAPDGS 2624 Score = 32.3 bits (72), Expect = 4.0 Identities = 52/250 (20%), Positives = 97/250 (38%), Gaps = 26/250 (10%) Query: 995 MAAKPLGCRPP--------ISKESSVDRPTFLDKD-GGLVEEPTPSPFLPSPSLKLPLSH 1045 ++ KP+G PP ++ + + F D D E P + + L Sbjct: 3377 LSQKPMGTMPPSMCMKPQQLAMQQQLANSFFPDTDLDKFAAEDIIDPIAKAKMVALKGIK 3436 Query: 1046 SALPSQALGGIASGLGMQNLNSSRQI----PSGNLGMFGNSGAAQARTMQQPPQPPVQPL 1101 + ++G +A G+ Q ++ Q PS +L +G+ Q R+ P QP P Sbjct: 3437 KVMAQGSIG-VAPGMNRQQVSLLAQRLSGGPSSDLQNHVAAGSGQERSAGDPSQPRPNPP 3495 Query: 1102 NSSQPSL----RAQVPQFL--SPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLY 1155 +Q + + Q ++L + Q+ L+ + IG++ + Q Sbjct: 3496 TFAQGVINEADQRQYEEWLFHTQQLLQMQLKVLEEQIGVHRKSRKALCAKQRTAKKAGRE 3555 Query: 1156 QLQLAYQRLQI---QQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQ---A 1209 + ++L++ QQ +Q Q + +++ + N QQQ QQ Q+Q Q A Sbjct: 3556 FPEADAEKLKLVTEQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSA 3615 Query: 1210 LLVKQPPPPP 1219 +L P P Sbjct: 3616 VLALSPSQSP 3625 >gi|239757861 PREDICTED: similar to armadillo repeat containing, X-linked 4 [Homo sapiens] Length = 2382 Score = 56.2 bits (134), Expect = 3e-07 Identities = 141/670 (21%), Positives = 224/670 (33%), Gaps = 113/670 (16%) Query: 33 NQSALGA-GGANSNGSAARVWGVATGSSS-------------GLAHCSVSGGDGKMDTMI 78 N++++G+ GA+ R W VA +S G+ + +G Sbjct: 1226 NEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIGTWARAGEQASGGLWA 1285 Query: 79 GDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHE--------GTVATGN-PSSICSP 129 G S+ W ++ G A+ +W + G++ G + G+ P S Sbjct: 1286 GGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASG 1345 Query: 130 VSAIGQNM--GNQNGNPT-GTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNN 186 VS +G+ G+ G + G+W +S S Q + G ++ Sbjct: 1346 VSWVGEEAIGGSWTGAENQASEGSWAGA----GAGNMSSVSYWAGVVDQAGGGSWAGTSD 1401 Query: 187 TNPMNSSPNPINAMQTNGLPNWGMAVGM---GAIIPPHLQGLPGANGSSVSQVSGGSAEG 243 + S P + Q +G +W A G G+++ P Q + + Q SGGS G Sbjct: 1402 QSGGGSKPRFED--QASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLG 1459 Query: 244 -ISNSVWGLSPG--NPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG-SGGNAW- 298 + S G G + + G S F + + A + Q G S V E S G +W Sbjct: 1460 HVDQSSGGAWAGTLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWA 1519 Query: 299 DSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGK 358 +SG G L G + G +GA GHP+ P ++G+ Sbjct: 1520 NSGDQISGGFLV---GIVDQANGGSWTGA-GHPA-----------SVGPKPIFEDQVSGR 1564 Query: 359 GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGE 418 GS V + +SWA +G AS G+ G + +G+ Sbjct: 1565 GSWADAREQVVGDSRLGLRDQSSGDSWA---GTGDQASGWFCVCPGSQTNGGSWGGASGQ 1621 Query: 419 GRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEA 478 D G G P Q++A ++ SP S+ T A Sbjct: 1622 ---------DVG-----------------GSRPGPTNQSSAGSWD-SPGSQVSGSCWTGA 1654 Query: 479 WGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWG 538 + G D +I W P A G + SG G WG Sbjct: 1655 GAVDQAGGCSKPGFEDQAIGGGF-------W---PGAGDQTGGGSRPGSEDQSSGIGSWG 1704 Query: 539 ---DSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEP---------PKPKSQHWGDGQ 586 + A A SG +W+G NQ +W P P+ + Q G G Sbjct: 1705 VAGGQVLGGARPGPADQSSGGSWAGTGNQ-SSGRSWIGPGDQAVDCSKPEFEDQACGGGS 1763 Query: 587 RSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTN 646 + A G WA S G+ GS ++ +G W + + + S Sbjct: 1764 WAGAGSQASGESWAGSRP-----GNEAIGGSRMGSEDQATGGSWARSEDQASGRFQVSFE 1818 Query: 647 TKANPGTNWG 656 +AN G +G Sbjct: 1819 VEANEGFWFG 1828 Score = 55.8 bits (133), Expect = 3e-07 Identities = 106/498 (21%), Positives = 166/498 (33%), Gaps = 85/498 (17%) Query: 475 GTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGP 534 G EA G + T A N + + + N SSVS W A W +++++ G Sbjct: 1350 GEEAIGGSWTGAENQASEGSWAGAGAGNMSSVSYWAGVVDQA--GGGSWAGTSDQSGGG- 1406 Query: 535 GVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSA 594 S A+ + +W+GA Q G + + W D Sbjct: 1407 -------SKPRFEDQASGEG--SWAGAGGQASGGSMLGPEDQSSGRSWAD---------- 1447 Query: 595 GGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG-----WNDTTRSGNSGWGNSTNTKA 649 D A S LGH+ + +G W ++SG G N TT G+ W A Sbjct: 1448 -TADQASGGSRLGHV--DQSSGGAWAGTLDQSGGGSKPRFENQTTEEGS--W-------A 1495 Query: 650 NPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASV----KQTGTGWIG-------GPVP 698 G G K GP+ + + N+ G V + G W G GP P Sbjct: 1496 GAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQANGGSWTGAGHPASVGPKP 1555 Query: 699 VKQKDSSEATGWEEPSPPSI-RRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQS--- 754 + + S W + + ++ + D +S GD + W P Q+ Sbjct: 1556 IFEDQVSGRGSWADAREQVVGDSRLGLRDQSS--GDSWAGTGDQASGWFCVCPGSQTNGG 1613 Query: 755 STTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTE 814 S + + T++ G+Q++ S G G +G P + Sbjct: 1614 SWGGASGQDVGGSRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAI 1673 Query: 815 NSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKS 874 P + G+ + SSG G ++G AG V A PA +S Sbjct: 1674 GGGFWPGA-GDQTGGGSRPGSEDQSSGIG----------SWGVAGGQVLGGARPGPADQS 1722 Query: 875 MQEGW-------------GSGGDEMNLSTSQWEDEE--GDVWNNAASQESTSSCSSWGNA 919 W G G ++ S ++ED+ G W A SQ +S SW + Sbjct: 1723 SGGSWAGTGNQSSGRSWIGPGDQAVDCSKPEFEDQACGGGSWAGAGSQ---ASGESWAGS 1779 Query: 920 PKKGLQKGMKTSGKQDEA 937 G G +D+A Sbjct: 1780 RPGNEAIGGSRMGSEDQA 1797 Score = 55.5 bits (132), Expect = 4e-07 Identities = 188/861 (21%), Positives = 299/861 (34%), Gaps = 147/861 (17%) Query: 149 GAWGNLLPQESTEPQTSTSQNVSFSAQPQNL-NTDG---PNNTNPMNSSPNPINAMQTNG 204 GA + +T P + + SA+PQ + N+ G P N + ++ N ++ + G Sbjct: 815 GAKNKIRGNPTTVPNSGVGPYTTDSARPQAVANSQGEVLPGAKNKVKANLNAVSKAEA-G 873 Query: 205 LPNWGMAVGMGAIIPPHLQGLPGA------NGSSVSQVSGG-------SAEGISNSVWGL 251 + G +V A+ H + LPGA N ++VS+ G + ++NS + Sbjct: 874 MGATG-SVQPQAVANSHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSAQPQAVANSQGEV 932 Query: 252 SPG--NPATGNSNSGFSQG-NGDTVNSA----LSAKQN-----------GSSSAVQKEGS 293 PG N GN N G DTV S L++ Q G+S+ V K G+ Sbjct: 933 LPGAKNKVKGNPNVVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNVVSKAGA 992 Query: 294 GGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNS 353 + S A P ++A + G N G S++ + G G Q S Sbjct: 993 REDTMGS---AQPQVVANSQRETLPGARNKVKGNSNAISKAEAGA--GIMGSVQVQVVAS 1047 Query: 354 DINGKGSTGWESPSVTSQN--PTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGST 411 G+ G ++ + N P + G + + S A+ + + SE + G+ N +G+T Sbjct: 1048 -FQGEVLPGAKNKVRGNSNAVPKAEAGADTVGS-AQPQAVANSQSE-TLLGARNKVKGNT 1104 Query: 412 ---GREGTGEGRRRDKG--IIDQGHIQLPRNDLDPRVLSNTGWGQTPVKQNTAWEFEESP 466 + GTG G R I+ + D + ++ + E E P Sbjct: 1105 IAVPKAGTGAGTRHSAQPQIVAGSQGETLPGARDKSMSTSEAEATAEDEAYAKPEAEAMP 1164 Query: 467 RSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDS 526 SE + +GT+A C TQ + +G V W+ A W Sbjct: 1165 TSESEGGSGTQA--CRKTQPNIHDYYWNGI--------GVEDWIAAER--------WIKF 1206 Query: 527 NNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKS-QHWGDG 585 + G W +S+S A+ S WSGA+++ +W S + W Sbjct: 1207 RFQTMDGD--WENSVSWADDENEASIGS---WSGASDKAGIIRSWAVACDETSVKSWAGA 1261 Query: 586 QRSNPA----WS-----AGGGDWADSSSVLGHLGDGKKNGSGW-DADSNRSGSGW----- 630 + N W+ A GG WA + G K +G W A++ SG W Sbjct: 1262 RAENVVGIGTWARAGEQASGGLWAGGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGN 1321 Query: 631 ---NDTTRSGNSGWGNSTNTKANPGTNW-GETLKPGPQQNWASKPQDNNVSNWGGAASVK 686 + +G + G+ +A+ G +W GE G +W + +W GA + Sbjct: 1322 QAIGELWAAGQASDGSWPGGQAS-GVSWVGEEAIGG---SWTGAENQASEGSWAGAGAGN 1377 Query: 687 QTGTGWIGGPVPVKQKDSSEATGWEEPSPPS-IRRKMEIDDGTSAWGDPSNYNNKTVNMW 745 + + G V D + W S S K +D S G + + + Sbjct: 1378 MSSVSYWAGVV-----DQAGGGSWAGTSDQSGGGSKPRFEDQASGEGSWAGAGGQ-ASGG 1431 Query: 746 DRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGE 805 P QSS + T + + V+ S G SG G Sbjct: 1432 SMLGPEDQSSGRSWADTADQASGGSRLGHVD-----------QSSGGAWAGTLDQSGGGS 1480 Query: 806 MPNVHSKT--ENSWGEPSSPSTLVDNGTAAWGKPPSSGSGWGDHPAEPPVAF-------- 855 P ++T E SW + G+ + SSG W + + F Sbjct: 1481 KPRFENQTTEEGSWAGAGGQA---GGGSKVGPEDQSSGRSWANSGDQISGGFLVGIVDQA 1537 Query: 856 ---GRAGAPVAASALCKPASKSMQEGWGSGGD--EMNLSTSQW---EDEEGDVWNNAASQ 907 GA AS KP + G GS D E + S+ + GD W Q Sbjct: 1538 NGGSWTGAGHPASVGPKPIFEDQVSGRGSWADAREQVVGDSRLGLRDQSSGDSWAGTGDQ 1597 Query: 908 ESTSSC---------SSWGNA 919 S C SWG A Sbjct: 1598 ASGWFCVCPGSQTNGGSWGGA 1618 Score = 39.3 bits (90), Expect = 0.033 Identities = 127/646 (19%), Positives = 215/646 (33%), Gaps = 112/646 (17%) Query: 121 GNPSSICSPVSAIGQNMGNQN---GNPTGTL--GAWGNLLPQESTEPQTSTSQNVSFSAQ 175 GNP++ + Q + Q NP G GA + T + + + SAQ Sbjct: 662 GNPNATSKAGTKADQRVCGQPLVVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSAQ 721 Query: 176 PQNL-NTDGP---NNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS 231 P+ + + G N + +PN + + VG GA+ LQ + + G Sbjct: 722 PEAVVSFQGEALLGTKNKVKGNPNVVLKAE----------VGEGAMGTAQLQIMASSKGE 771 Query: 232 SVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKE 291 ++ S +G SN+V G TG+ + V K G+ + V Sbjct: 772 ALLD-SKNKVKGNSNAVSKAGAGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNS 830 Query: 292 GSGGNAWDSGPPAGPGILAWGRG---------------------SGNNGVGNIHSGAWGH 330 G G DS A P +A +G +G G++ A + Sbjct: 831 GVGPYTTDS---ARPQAVANSQGEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVAN 887 Query: 331 PSRST----SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWA 386 T N V G W + D G + +V + V PG ++ Sbjct: 888 SHCETLPGAKNKVRGNWNAVSKAGAGMDTRGSA----QPQAVANSQGEVLPGAKNKVKGN 943 Query: 387 KAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKG----IIDQGHIQLPRNDLDPR 442 S A E + + S+ RE R + KG + G + P+ Sbjct: 944 PNVVSKAGAREDTVGSTQPQVLASSQRETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQ 1003 Query: 443 VLSNTG---------------------------WGQTPVKQNTAWEFEESPRSERKNDNG 475 V++N+ G V+ +++ E P ++ K Sbjct: 1004 VVANSQRETLPGARNKVKGNSNAISKAEAGAGIMGSVQVQVVASFQGEVLPGAKNKVRGN 1063 Query: 476 TEAWGCAATQASNSGGKNDGSIMNSTNTS--SVSGWVNAPPAAVP-ANTGWGDSNNKAPS 532 + A A A G ++ NS + + V AVP A TG G ++ P Sbjct: 1064 SNAVPKAEAGADTVGSAQPQAVANSQSETLLGARNKVKGNTIAVPKAGTGAGTRHSAQPQ 1123 Query: 533 -GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPA 591 G G+++ A KS A ED++ KP+++ + Sbjct: 1124 IVAGSQGETL------PGARDKSMSTSEAEATAEDEAYA-----KPEAEAMPTSE----- 1167 Query: 592 WSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGW-NDTTRSGNSGWGNSTN---- 646 S GG ++ D NG G + + W ++ + W NS + Sbjct: 1168 -SEGGSGTQACRKTQPNIHDYYWNGIG--VEDWIAAERWIKFRFQTMDGDWENSVSWADD 1224 Query: 647 -TKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTGTG 691 +A+ G+ G + K G ++WA + +V +W GA + G G Sbjct: 1225 ENEASIGSWSGASDKAGIIRSWAVACDETSVKSWAGARAENVVGIG 1270 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 55.1 bits (131), Expect = 6e-07 Identities = 106/456 (23%), Positives = 167/456 (36%), Gaps = 105/456 (23%) Query: 954 REPAEEALKSNNMNLDQAMSALLEKKVDVDKRGLGVTDHNGMAAKPLGCRPPISKESSVD 1013 R+P+ + L + +A +K D +G + D +GM + P S V Sbjct: 2159 RKPSSKGLACGSK---EAKDLKARRKKSQDGKGC-LLDSSGMLSPVDSLESPHGYLSDVA 2214 Query: 1014 RPTFLDKDGGLVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPS 1073 P L PSPF SPS+ PL+H LP G + LG+ +LN + + Sbjct: 2215 SPPLL-----------PSPFQQSPSV--PLNH--LP----GMPDTHLGIGHLNVAAKPEM 2255 Query: 1074 GNLGMFGNSGAAQARTMQQPPQPPVQPL---------NSSQPSLRAQVPQFLSPQVQAQL 1124 LG G + PP+ P+ +SS +L V S Q + Sbjct: 2256 AALG-----GGGRLAFETGPPRLSHLPVASGTSTVLGSSSGGALNFTVGGSTSLNGQCEW 2310 Query: 1125 LQFAAKNIGLN------------------PALLTSPINPQHMTMLNQLYQLQLAYQ---- 1162 L + N P+L + P H ++ ++YQ Sbjct: 2311 LSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHSSLAASALSQMMSYQGLPS 2370 Query: 1163 -RLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLAQALLVKQPPPPPPP 1221 RL Q ++Q Q+ +++ Q+Q NLQ Q Q+ L QPPPPPP Sbjct: 2371 TRLATQPHLVQTQQVQPQNLQMQQQ-------NLQPANIQQQQSL-------QPPPPPPQ 2416 Query: 1222 PHLSLHPSA----GKSAMDSFPS----HPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPN 1273 PHL + +A G+S + PS P P + T Q SP P + + P Sbjct: 2417 PHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTSLPSSLVPP- 2475 Query: 1274 MNVNSMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIG 1333 +T + PSQ ++ + +DN PS + ++P L+ Sbjct: 2476 -------VTAAQFLTPPSQH-------SYSSPVDNTPSHQLQVPEHPF--------LTPS 2513 Query: 1334 PPGKSSIDDSYGRYDLIQNSESPASPPVAVPHSWSR 1369 P S ++ SE +SPP ++ +R Sbjct: 2514 PESPDQWSSSSPHSNVSDWSEGVSSPPTSMQSQIAR 2549 >gi|18644886 forkhead box P1 isoform 1 [Homo sapiens] Length = 677 Score = 53.9 bits (128), Expect = 1e-06 Identities = 53/161 (32%), Positives = 72/161 (44%), Gaps = 20/161 (12%) Query: 1085 AQARTMQQPPQPPVQPL-----NSSQPSLRAQV------PQFLSPQVQAQLLQFAAKNIG 1133 A+ +QQ Q V L N QP+L+ V PQ ++PQ Q+LQ Sbjct: 65 ARQLLLQQQQQQQVSGLKSPKRNDKQPALQVPVSVAMMTPQVITPQQMQQILQQQV---- 120 Query: 1134 LNPALLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTIT 1193 L+P L + Q ML Q QLQ Y++ Q Q Q+ Q+ +G +++QQVA Sbjct: 121 LSPQQLQVLLQQQQALMLQQ-QQLQEFYKKQQEQLQLQLLQQQHAGKQPKEQQQVATQQL 179 Query: 1194 NLQQQIQQHQRQLAQALLVKQPPP----PPPPPHLSLHPSA 1230 QQQ+ Q Q+ Q LL Q P P L L P A Sbjct: 180 AFQQQLLQMQQLQQQHLLSLQRQGLLTIQPGQPALPLQPLA 220 >gi|62953127 polyhomeotic 1-like [Homo sapiens] Length = 1004 Score = 53.5 bits (127), Expect = 2e-06 Identities = 58/227 (25%), Positives = 91/227 (40%), Gaps = 22/227 (9%) Query: 1038 SLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPP 1097 SL L + + G + G G Q Q+PS +G G S + + QP P Sbjct: 261 SLNLSQAGGGSGNSIPGSMGPGGGGQAHGGLGQLPSSGMG--GGSCPRKGTGVVQP-LPA 317 Query: 1098 VQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLNQLYQL 1157 Q + SQ S Q + +A+ +N+G+N +P Q + Q+ Sbjct: 318 AQTVTVSQGS---QTEAESAAAKKAEADGSGQQNVGMNLTRTATPAPSQTLISSATYTQI 374 Query: 1158 Q-----LAYQRLQIQQQMLQAQRNVSGSMRQQEQ----QVARTITNLQ-------QQIQQ 1201 Q Q++ +QQ+ + Q+ ++ +QQ Q Q+ T T+LQ QQ QQ Sbjct: 375 QPHSLIQQQQQIHLQQKQVVIQQQIAIHHQQQFQHRQSQLLHTATHLQLAQQQQQQQQQQ 434 Query: 1202 HQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLP 1248 Q+Q QA + P PP PP + PS + + P P Sbjct: 435 QQQQQPQATTLTAPQPPQVPPTQQVPPSQSQQQAQTLVVQPMLQSSP 481 >gi|239743293 PREDICTED: mucin 12 [Homo sapiens] Length = 5478 Score = 53.1 bits (126), Expect = 2e-06 Identities = 182/901 (20%), Positives = 319/901 (35%), Gaps = 133/901 (14%) Query: 2 ATGSAQGNFTGHTKKTNGNNG---TNGALVQSPSNQSALGAGGANSNGSAARVWGVATGS 58 A+G ++ + T H+ T+ + T ALV+ P++ + S GS A + + Sbjct: 1933 ASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS-------SPGSTATTHFPDSST 1985 Query: 59 SSGLAHCSVSGGDGK--MDTMIGDGRSQNC--WGASNSNAGINLNLNPNANPAAW--PVL 112 +SG + S + + T++ RS G S ++ + ++ A P + P L Sbjct: 1986 TSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGL 2045 Query: 113 GHEGTV---ATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNL-LPQESTEPQTSTSQ 168 + T + +P++ SP S + ++ G+ P +T P S Sbjct: 2046 SEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHS 2105 Query: 169 NVSFSAQ--------PQNLNTDGPNN-TNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIP 219 S S+ P + T GP+ + +SSP + + G ++ G + Sbjct: 2106 TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTT-ALSFGQESTT- 2163 Query: 220 PHLQGLPGANGSSV---SQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSA 276 PG+ +++ S S G E S V S G+P T S + S+ Sbjct: 2164 --FHSSPGSTHTTLFPDSTTSSGIVEA-STRVHS-STGSPRTTLSPA-----------SS 2208 Query: 277 LSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGIL----AWGRGSGNNGVGNIHSGAW--GH 330 S G S+A Q + + S P + + R G+ + + + GH Sbjct: 2209 TSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGH 2268 Query: 331 PSRST--SNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS----QNPTVQPGGEHMNS 384 +ST + + P + HS + G+ +T SP T T PG ++ Sbjct: 2269 SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAST 2328 Query: 385 --WAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPR 442 ++ S TT S S G E +T R G P + P Sbjct: 2329 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS----------PASTTTPG 2378 Query: 443 VL--SNTGWGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNS 500 + S T + +P T F +P + + + T A+ + ++ + + Sbjct: 2379 LSEESTTVYSSSPGSTETT-VFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGLT 2437 Query: 501 TNTSSVSGWVNAPPAAVPAN---TGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHA 557 +++ G + +PA G+ + PS G G ++S +T+ Sbjct: 2438 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTP 2497 Query: 558 WSGAANQEDKSPTWGEPPKP----KSQHWGDGQRS-----NPAWSAGGGDWADSSSVLGH 608 + + + + G P P KS + RS +PA + G +SS+ H Sbjct: 2498 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST--SH 2555 Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA 668 G + + + + G + TT + G ST+T P + T GP Q Sbjct: 2556 SQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG---STDTTLLPAS----TTTSGPSQEST 2608 Query: 669 ---SKPQDNNVSNWGG---AASVKQTGTGWIGGPVPVKQK---DSSEATGWEEPSPPSIR 719 S P + + G A S Q T + P DS+ ++G E S Sbjct: 2609 TSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRV-- 2666 Query: 720 RKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPP 779 S+ G P T++ +P +Q +TT T +T T+ + T P Sbjct: 2667 --------HSSTGSPRT----TLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAP 2714 Query: 780 PHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPS 839 ++ T +RSP G P H ++ S ST+ + A G PS Sbjct: 2715 VEES-TTYHRSP------------GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPS 2761 Query: 840 S 840 S Sbjct: 2762 S 2762 Score = 47.0 bits (110), Expect = 2e-04 Identities = 120/567 (21%), Positives = 202/567 (35%), Gaps = 100/567 (17%) Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS---QNPTVQPGGEHMNSWAK 387 P+ +TS+GV+ E + S+S +T + + TS Q PT S + Sbjct: 3013 PATTTSSGVSEE-----SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA--------SHSS 3059 Query: 388 AASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNT 447 S+ T S GS+ S + +T G+ + ++ I + S+T Sbjct: 3060 QGSTEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSST 3116 Query: 448 G---WGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSI-MNSTNT 503 G TP +A EES + +W ++ + G + +++T Sbjct: 3117 GSLHTTLTPASSTSAGLQEESTTFQ--------SWPSSSDTTPSPPGTTAAPVEVSTTYH 3168 Query: 504 SSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSI----SSTAV----STAAAAKSG 555 S S +A G + + S PG G ++ S+T+V T + SG Sbjct: 3169 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 3228 Query: 556 HAWSGA-------ANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH 608 + A A +KS T+ P+ +PA + G S H Sbjct: 3229 STETTALPGSTTTAGLSEKSTTFYSSPRSPDT------TLSPASTTSSG--VSEESTTSH 3280 Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKP------- 661 G + + + + G T + G ST+T +PG+ +L P Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPG---STDTTLSPGSTTASSLGPESTTFHS 3337 Query: 662 GPQQNWASKPQDNNVSNWGGAASV---KQTG---TGWIGGPVPVKQKDSSEATGWEE--- 712 GP + DN ++ AS TG T +Q +S+ W Sbjct: 3338 GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKD 3397 Query: 713 --PSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSN 770 P+PP+ ++ T++ G PS+ + SSTT + +TT S+ Sbjct: 3398 TTPAPPTTTSAF-VELSTTSHGSPSSTPTTHFSA---------SSTTLGRSEESTTVHSS 3447 Query: 771 TTHRVETPPPHQA--------GTQLNRSP-----LLGPGRKVSSGWGEMPNV-HSKTENS 816 TP P ++ T + SP + P +SG GE HS T ++ Sbjct: 3448 PVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 3507 Query: 817 WGE-PSSPSTLVDNGTAAWGKPPSSGS 842 PS+ S LV+ T+ P S+ + Sbjct: 3508 ISSAPSTTSALVEEPTSYHSSPGSTAT 3534 Score = 45.8 bits (107), Expect = 3e-04 Identities = 137/674 (20%), Positives = 232/674 (34%), Gaps = 116/674 (17%) Query: 331 PSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTS---QNPTVQPGGEHMNSWAK 387 P+ +TS+GV+ E + S+S +T + + TS Q PT S + Sbjct: 1456 PATTTSSGVSEE-----SSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT--------SHSS 1502 Query: 388 AASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNT 447 S+ T S GS+ S + +T G+ + ++ I + S+T Sbjct: 1503 QGSTEATLSPGSTTASSLGQQSTTFHSSPGD---TETTLLPDDTITSGLVEASTPTHSST 1559 Query: 448 G---WGQTPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSI-MNSTNT 503 G TP +A EES + +W ++ + G + +++T Sbjct: 1560 GSLHTTLTPASSTSAGLQEESTTFQ--------SWPSSSDTTPSPPGTTAAPVEVSTTYH 1611 Query: 504 SSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSI----SSTAV----STAAAAKSG 555 S S +A G + + S PG G ++ S+T+V T + SG Sbjct: 1612 SRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSG 1671 Query: 556 HAWSGA-------ANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGH 608 + A A +KS T+ P+ +PA + G S H Sbjct: 1672 STETTALPGSTTTAGLSEKSTTFYSSPRSPDT------TLSPASTTSSG--VSEESTTSH 1723 Query: 609 LGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWA 668 G + + + + G T + G ST+T +PG+ +L P + Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPG---STDTTLSPGSTTASSLGPESTTFHS 1780 Query: 669 SK--------PQDNNVSNWGGAASVKQTGTGWIGGPVP-----VKQKDSSEATGWEE--- 712 S P + S A++ + TG + +Q +S+ W Sbjct: 1781 SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKD 1840 Query: 713 --PSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSN 770 P+PP+ ++ T++ G PS+ + SSTT + +TT S+ Sbjct: 1841 TMPAPPTTTSAF-VELSTTSHGSPSSTPTTHFSA---------SSTTLGRSEESTTVHSS 1890 Query: 771 TTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVH-SKTENSWGEPSSPSTLVDN 829 TP P ++ T S L+ S G +H ++ + G T + Sbjct: 1891 PVATATTPSPARSTT----SGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSS 1946 Query: 830 GTAAWGKPPSSGSGWGDHPAEPPVAFGRAGAPVAASALCKPASKSMQEGWGSGGDEMNLS 889 T PPS+ S + P +P + + P S + SG E + + Sbjct: 1947 TTHTISSPPSTTSALVEEPT------SYHSSPGSTATTHFPDSSTT-----SGRSEESTA 1995 Query: 890 TSQWEDEEGDVWNNAASQ------ESTSSCSSWGNAPKKGLQKGMKTSGKQDEAWIMSRL 943 + +D G + A S EST+S S G+ L T G + Sbjct: 1996 SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE-------- 2047 Query: 944 IKQLTDMGFPREPA 957 K T PR PA Sbjct: 2048 -KSTTFHSSPRSPA 2060 Score = 43.1 bits (100), Expect = 0.002 Identities = 159/813 (19%), Positives = 278/813 (34%), Gaps = 120/813 (14%) Query: 53 GVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVL 112 GV+ SS+ + + D+ G SQ + +S L+P + A+ L Sbjct: 4103 GVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTAS--SL 4160 Query: 113 GHEGTV---ATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQN 169 G + T + G+ + P I + + + G+ L S+ ++ Sbjct: 4161 GQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEES 4220 Query: 170 VSFSAQPQNLNTD-GPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPH----LQG 224 +F + P + +T P +T + + + + P + + + Sbjct: 4221 TTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHS 4280 Query: 225 LPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGN---GDTVNSALSAKQ 281 PGA G+++ + S + G P T +SG ++ G T + LS K Sbjct: 4281 SPGATGTALFP---------TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEK- 4330 Query: 282 NGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNG 341 S++ S G+ S ++ G++H+ A+ PS +T GV+ Sbjct: 4331 --STTFYSSPRSPDTTLSPASTTSSGVSEESTTS-HSRPGSMHTTAF--PSSTTMPGVS- 4384 Query: 342 EWGKPPNQHSNSDINGKGSTGWE-SPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSS 400 Q S + + GST SP T+ + G E + S+ TT ++ Sbjct: 4385 -------QESTASHSSPGSTDTTLSPGSTTASSL---GPESTTFHSSPGSTETTLLPDNT 4434 Query: 401 DGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQ--------- 451 SG + TG P L P S T G+ Sbjct: 4435 TASGLLEASTPVHSSTGS----------------PHTTLSPAG-STTRQGESTTFQSWPN 4477 Query: 452 ----TPVKQNTAWEFEESPRSERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVS 507 TP T F E + + + T +A+ S + G+++ S +T SS Sbjct: 4478 SKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS--STTLGRSEES---TTVHSSPV 4532 Query: 508 GWVNAPPAAVPANTGWGDSNNKAPSGPG---VWGDSISSTAVSTAAAAKSGHAWSGAANQ 564 P A +G + + S PG S+T + + H+ + Sbjct: 4533 ATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTIS 4592 Query: 565 EDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDAD-- 622 S T +P S H G S + DSS+ G + + S DA Sbjct: 4593 SAPSTTSALVEEPTSYHSSPG-------STATTHFPDSSTTSGRSEESTASHSSQDATGT 4645 Query: 623 ------SNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQN---WASKPQD 673 S S TT +SG S T A PG+ T PG + + S P Sbjct: 4646 IVLPARSTTSVLLGESTTSPISSG---SMETTALPGS----TTTPGLSEKSTTFHSSPSS 4698 Query: 674 NNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIRRKMEIDDGTSAWGD 733 +++ +++ +G SS PSP +++ T+ Sbjct: 4699 TPTTHFSASSTT-------LGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSS 4751 Query: 734 PSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPP-PHQAGTQLNRSPL 792 P + +T++ +SST + + + T+ S+TTH + +PP A + S Sbjct: 4752 PGS--TQTMHF-------PESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYH 4802 Query: 793 LGPGRKVSSGWGEMPNVHSKTENSWGEPSSPST 825 PG ++ + E ++E S SSP T Sbjct: 4803 SSPGSIATTHFPESSTTSGRSEESTASHSSPDT 4835 Score = 36.6 bits (83), Expect = 0.21 Identities = 114/562 (20%), Positives = 193/562 (34%), Gaps = 105/562 (18%) Query: 453 PVKQNTAWEFEESPR---SERKNDNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGW 509 P T+ EES S + T + A S + ++S++SG Sbjct: 517 PESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR 576 Query: 510 VNAPPAAVPANTGWGDSNNKAPSGPGVW-GDS----ISSTAVSTAAAAKSGHAWSGAANQ 564 A+ + + A S P V GDS ISS ++ T A S + Sbjct: 577 SEESKASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGS----TTKPGL 632 Query: 565 EDKSPT-WGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADS 623 +KS T + P P + H PA G S H G + + + + Sbjct: 633 SEKSTTFYSSPRSPDTTHL-------PASMTSSG--VSEESTTSHSRPGSTHTTAFPGST 683 Query: 624 NRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAA 683 G T + G T+T +PG+ +L P + S+P + Sbjct: 684 TMPGLSQESTASHSSPG---PTDTTLSPGSTTASSLGP-EYTTFHSRPGSTETT----LL 735 Query: 684 SVKQTGTGWIGGPVPV------------------KQKDSSEATGWEE-----PSPPSIRR 720 T +G + +PV +Q +S+ W P+PP+ Sbjct: 736 PDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTS 795 Query: 721 KMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTT---------------TNTTT--- 762 ++ T++ G PS+ ++ + +++ STT ++TT+ Sbjct: 796 AF-VEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRG 854 Query: 763 -TTTTTTSNTTHRVETPPPHQAG-----TQLNRSP-----LLGPGRKVSSGWGEMPNVHS 811 +TT+ S+TTH + + P + T + SP P +SG E Sbjct: 855 EESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASH 914 Query: 812 KTENSWG-----EPSSPSTLVDNGTAAWGKPPSSGS-------GWGDHPAEPPVAFGRAG 859 ++++ G S+ S L+ T + P SSGS G P + Sbjct: 915 SSQDATGTIVLPARSTTSVLLGESTTS---PISSGSMETTALPGSTTTPGLSERSTTFHS 971 Query: 860 APVAASALCKPASKS----MQEGWGSGGDEMNLSTSQWEDEEGDVWNNAASQESTSSCSS 915 +P + + PAS + +E S + T+ + D S+ ST+S SS Sbjct: 972 SPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPD---STTTPGLSRHSTTSHSS 1028 Query: 916 WGNAPKKGLQKGMKTSGKQDEA 937 G+ L TSG E+ Sbjct: 1029 PGSTDTTLLPASTTTSGPSQES 1050 Score = 35.0 bits (79), Expect = 0.62 Identities = 148/754 (19%), Positives = 246/754 (32%), Gaps = 131/754 (17%) Query: 114 HEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFS 173 H ATG +++ SA +G +P + LP +T S ++ +F Sbjct: 3196 HSSPGATG--TALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLS-EKSTTFY 3252 Query: 174 AQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGS-S 232 + P++ +T +P +++ + ++ T G H PG+ Sbjct: 3253 SSPRSPDT----TLSPASTTSSGVSEESTTSHSRPGST---------HTTAFPGSTTMPG 3299 Query: 233 VSQVSGGSAEGISNSVWGLSPGNPAT---GNSNSGFSQGNGDTVNSALSAKQNGSS---S 286 VSQ S S ++ LSPG+ G ++ F G G T + L S + Sbjct: 3300 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEA 3359 Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRST-----SNGVNG 341 + S G+ + PAG G + N P+ ++ S +G Sbjct: 3360 STPVHSSTGSPHTTLSPAG-STTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHG 3418 Query: 342 EWGKPPNQHSNSDINGKG-----STGWESPSVTSQNP-----TVQPGGEHMNSWAKAASS 391 P H ++ G +T SP T+ P T E ++ + S Sbjct: 3419 SPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGS 3478 Query: 392 GTTASEGSSDGSGNHNEGSTGREGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGWGQ 451 T SD + E ST + ++ P + +T Sbjct: 3479 TQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSP--GSTATTH 3536 Query: 452 TPVKQNTAWEFEESPRSERKND-NGTEAWGCAATQASNSGGKNDGSIMN-STNTSSVSGW 509 P T+ EES S D GT +T + G I + S T+++ G Sbjct: 3537 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 3596 Query: 510 VNAPPAAVPANTGWGDSNNKAPSGPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSP 569 P + + T + +P P +T +S A+ SG + E+ + Sbjct: 3597 TTTPGLSEKSTTF-----HSSPRSP--------ATTLSPASTTSSGVS-------EESTT 3636 Query: 570 TWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSG 629 + P + + D + P S S H G + + A + SGS Sbjct: 3637 SHSRPGSTHTTAFPDST-TTPGLSR--------HSTTSHSSPGSTDTTLLPASTTTSGSS 3687 Query: 630 WNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWASKPQDNNVSNWGGAASVKQTG 689 TT +SG ST+T +PG+ A S Q Sbjct: 3688 QESTTSHSSSG---STDTALSPGSTT--------------------------ALSFGQES 3718 Query: 690 TGWIGGPVPVKQK---DSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWD 746 T + P DS+ ++G E S S+ G P T++ Sbjct: 3719 TTFHSSPGSTHTTLFPDSTTSSGIVEASTRV----------HSSTGSPRT----TLSPAS 3764 Query: 747 RNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEM 806 +P +Q +T T +T T+ + T P ++ T +RSP G Sbjct: 3765 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES-TTYHRSP------------GST 3811 Query: 807 PNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPSS 840 P H ++ S ST+ + A G PSS Sbjct: 3812 PTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSS 3845 Score = 35.0 bits (79), Expect = 0.62 Identities = 65/298 (21%), Positives = 107/298 (35%), Gaps = 37/298 (12%) Query: 1225 SLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVNSMDMTGG 1284 ++H S +A P+ T GL + T SSP G M+ D T G Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTT-YHSSP---------GSTQTMHFPESDTTSG 3492 Query: 1285 LSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGKSSIDDSY 1344 + + S TH ++ + PS S L + P+ + + PG + SS Sbjct: 3493 RGEESTTSHSST----TH--TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 3546 Query: 1345 GRYDLIQNSESPASPPVAVP----HSWSRAKSDSDKISNGSSINWPPEFHPGVPWKGLQN 1400 +S A+ + +P S +S + IS+GS G Sbjct: 3547 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM--------ETTALPGSTT 3598 Query: 1401 IDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHTQASLSHE 1460 ++ T S P P TT+ + S G + ++ S ++HT A Sbjct: 3599 TPGLSEKSTTFHSSPRSPA--TTLSPAS---TTSSGVSEESTTSHSRPGSTHTTAFPDST 3653 Query: 1461 LWKVPRNSTAPTRPPPGLTN----PKPSSTWGASPLGWTSSYSSGSAWSTDTSGRTSS 1514 + + PG T+ P ++T G+S TS SSGS + + G T++ Sbjct: 3654 TTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTA 3711 Score = 33.1 bits (74), Expect = 2.3 Identities = 171/869 (19%), Positives = 281/869 (32%), Gaps = 119/869 (13%) Query: 23 TNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKM--DTMIGD 80 T L Q P+ + G + S + G S H S + + D I Sbjct: 1488 TTSDLSQEPTTSHS-SQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 1546 Query: 81 GRSQNCWGASNSNAGINLNLNPNANPAA-----------WPVLGHEGTVATGNPSSICSP 129 G + +S ++ L P ++ +A WP P + +P Sbjct: 1547 GLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWP---SSSDTTPSPPGTTAAP 1603 Query: 130 VSAIGQNMGNQNGNPTGTLGAWGNLL--PQESTEPQTS--TSQNVSFSAQPQNLNTDGPN 185 V + PT A L +EST +S + F + G Sbjct: 1604 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 1663 Query: 186 NTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQG--LPGANGSSVSQVSGGSAEG 243 T+P++S + +T LP G+ P S S S G +E Sbjct: 1664 TTSPISSG-----STETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEE 1718 Query: 244 ISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPP 303 + S PG+ T + G + G + S S GS+ GS + Sbjct: 1719 STTS--HSRPGSTHT-TAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGS-----TTASS 1770 Query: 304 AGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGW 363 GP + G+ + S V+ G P ++ ++ GST Sbjct: 1771 LGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSP-----HTTLSPAGSTTR 1825 Query: 364 ESPSVTSQN-PTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEGRRR 422 + S T Q+ P+ + + A +T S GS + + ++ T GR Sbjct: 1826 QGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASS---TTLGRSE 1882 Query: 423 DKGIIDQGHIQLP------RNDLDPRVLSNTGWGQTPVKQNTAWEFEESPRSERKNDNGT 476 + + + R+ V +T + +P T E S S R ++ T Sbjct: 1883 ESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT 1942 Query: 477 EAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVP---ANTGWGDSNNKAPSG 533 ++T + S + S + TS S + P +G + + + S Sbjct: 1943 SH---SSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 1999 Query: 534 PGVWGDSI----SSTAV----STAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDG 585 G + S+T+V ST + SG + A +P E KS + Sbjct: 2000 QDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSE----KSTTFHSS 2055 Query: 586 QRS-----NPAWSAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSG 640 RS +PA + G S H G + + + + G + TT + G Sbjct: 2056 PRSPATTLSPASTTSSG--VSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2113 Query: 641 WGNSTNTKANPGTNWGETLKPGPQQNWA---SKPQDNNVSNWGG---AASVKQTGTGWIG 694 ST+T P + T GP Q S P + + G A S Q T + Sbjct: 2114 ---STDTTLLPAS----TTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHS 2166 Query: 695 GPVPVKQK---DSSEATGWEEPSPPSIRRKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPV 751 P DS+ ++G E S S+ G P T++ +P Sbjct: 2167 SPGSTHTTLFPDSTTSSGIVEASTRV----------HSSTGSPRT----TLSPASSTSPG 2212 Query: 752 IQSSTTTNTTTTTTTTTSNTTHRVETPPPHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHS 811 +Q +T T +T T+ + T P ++ T +RSP G P H Sbjct: 2213 LQGESTAFQTHPASTHTTPSPPSTATAPVEES-TTYHRSP------------GSTPTTHF 2259 Query: 812 KTENSWGEPSSPSTLVDNGTAAWGKPPSS 840 ++ S ST+ + A G PSS Sbjct: 2260 PASSTTSGHSEKSTIFHSSPDASGTTPSS 2288 Score = 31.2 bits (69), Expect = 8.9 Identities = 65/305 (21%), Positives = 104/305 (34%), Gaps = 29/305 (9%) Query: 1218 PPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTKEQQSSPNTFAPYPLAGLNPNMNVN 1277 P PP S ++ S S P T T T+ P G M+ Sbjct: 788 PAPPTTTSAFVEPSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSP--GSTQTMHFP 845 Query: 1278 SMDMTGGLSVKDPSQSQSRLPQWTHPNSMDNLPSAASPLEQNPSKHGAIPGGLSIGPPGK 1337 D T G + + S TH ++ + PS S L + P+ + + PG + Sbjct: 846 ESDTTSGRGEESTTSHSST----TH--TISSAPSTTSALVEEPTSYHSSPGSTATTHFPD 899 Query: 1338 SSIDDSYGRYDLIQNSESPASPPVAVP----HSWSRAKSDSDKISNGSSINWPPEFHPGV 1393 SS +S A+ + +P S +S + IS+GS Sbjct: 900 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSM--------ETT 951 Query: 1394 PWKGLQNIDPENDPDVTPGSVPTGPTINTTIQDVNRYLLKSGGKLSDIKSTWSSGPTSHT 1453 G ++ T S P P TT+ + S G + ++ S ++HT Sbjct: 952 ALPGSTTTPGLSERSTTFHSSPRSPA--TTLSPAS---TTSSGVSEESTTSRSRPGSTHT 1006 Query: 1454 QASLSHELWKVPRNSTAPTRPPPGLTN----PKPSSTWGASPLGWTSSYSSGSAWSTDTS 1509 A + + PG T+ P ++T G S TS SSGS + + Sbjct: 1007 TAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP 1066 Query: 1510 GRTSS 1514 G T++ Sbjct: 1067 GSTTA 1071 >gi|109255251 loricrin [Homo sapiens] Length = 312 Score = 52.8 bits (125), Expect = 3e-06 Identities = 49/194 (25%), Positives = 71/194 (36%), Gaps = 7/194 (3%) Query: 227 GANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSS 286 G GS GG + G + + S G ++G + FS G G A+ + G S Sbjct: 107 GGGGSGCFSSGGGGSSGGGSGCFS-SGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVS 165 Query: 287 AVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP 346 + G G + SG G G G G +G G SG G S+ Sbjct: 166 SGGSSGGGSGCFSSG---GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQ 222 Query: 347 PNQ-HSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGN 405 P+ +S G G +G S + G + S + G+ GSS G G Sbjct: 223 PSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGG 282 Query: 406 HNEGSTGREGTGEG 419 + S G G+G+G Sbjct: 283 GS--SVGGSGSGKG 294 Score = 49.3 bits (116), Expect = 3e-05 Identities = 53/196 (27%), Positives = 70/196 (35%), Gaps = 16/196 (8%) Query: 224 GLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNG 283 G G +G SV GG + G + + G +S G S G G S+ +G Sbjct: 79 GCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSG 138 Query: 284 SSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEW 343 S G GG + + G ++ G GS G G SG G S G +G Sbjct: 139 GGSGCFSSGGGGFSGQAVQCQSYGGVSSG-GSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197 Query: 344 GKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGS 403 G +S +G G + + TS P GG SSG S GS S Sbjct: 198 G------GSSGGSGSGYVSSQQVTQTSCAPQPSYGG---------GSSGGGGSGGSGCFS 242 Query: 404 GNHNEGSTGREGTGEG 419 GS+G G G Sbjct: 243 SGGGGGSSGCGGGSSG 258 Score = 44.3 bits (103), Expect = 0.001 Identities = 70/323 (21%), Positives = 98/323 (30%), Gaps = 55/323 (17%) Query: 38 GAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDTMIGDGRSQNCWGASNSNAGIN 97 G GG + G G +G S + C SGG G G G S G G Sbjct: 24 GGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGG 83 Query: 98 LNLNPNANPAAWPVLGHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQ 157 + + G G ++G S C G + G +G G+ G Sbjct: 84 SGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGG---- 139 Query: 158 ESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAI 217 +S FS Q + G+ + G + G Sbjct: 140 ---GSGCFSSGGGGFSGQ--------------------AVQCQSYGGVSSGGSSGGGSGC 176 Query: 218 IPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSAL 277 G G SV SGG G G ++G S SG+ + Sbjct: 177 FS------SGGGGGSVCGYSGG----------GSGCGGGSSGGSGSGY-----------V 209 Query: 278 SAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSN 337 S++Q +S + GG + G G G + G G G++G G SG S Sbjct: 210 SSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGGG 269 Query: 338 GVNGEWGKPPNQHSNSDINGKGS 360 V G G S + G GS Sbjct: 270 SVCG-GGSSGGGGGGSSVGGSGS 291 Score = 42.0 bits (97), Expect = 0.005 Identities = 50/181 (27%), Positives = 69/181 (38%), Gaps = 27/181 (14%) Query: 238 GGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNA 297 GGS G S S G S G +G G S G G + GS +V+ G GG++ Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGG--GGGIGGCGGGSGGSVKYSGGGGSS 97 Query: 298 ------WDSG-------PPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWG 344 + SG G G G G ++G G G+ G S S+G G G Sbjct: 98 GGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGG----GSSGGGSGCFSSGGGGFSG 153 Query: 345 KPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSG 404 + S ++ GS+G S +S G S + G+ GSS GSG Sbjct: 154 QAVQCQSYGGVSSGGSSGGGSGCFSS--------GGGGGSVCGYSGGGSGCGGGSSGGSG 205 Query: 405 N 405 + Sbjct: 206 S 206 Score = 36.2 bits (82), Expect = 0.28 Identities = 46/178 (25%), Positives = 58/178 (32%), Gaps = 19/178 (10%) Query: 254 GNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGR 313 G +G GF G G S+ S G GG + SG G GI G Sbjct: 25 GGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGS--SGGGGGGGIGGCGG 82 Query: 314 GSGNN------------GVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGST 361 GSG + G G SG G S S+G G G S+ G GS+ Sbjct: 83 GSGGSVKYSGGGGSSGGGSGCFSSGGGG--SGCFSSGGGGSSGGGSGCFSS---GGGGSS 137 Query: 362 GWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGREGTGEG 419 G S +S S+ +S G++ SG G G G G Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSG 195 >gi|221139761 zinc finger protein 853 [Homo sapiens] Length = 659 Score = 52.4 bits (124), Expect = 4e-06 Identities = 45/134 (33%), Positives = 66/134 (49%), Gaps = 9/134 (6%) Query: 1086 QARTMQQPPQPPVQP----LNSSQPSLRAQV-PQFLSPQVQAQLLQFAAKNIGLNPALLT 1140 Q + ++Q P+P QP L QP L Q PQ Q +QL Q K+ ++ L Sbjct: 90 QLQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDGQQQLSQLQQ--EKHQSVHHQELK 147 Query: 1141 SPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQ 1200 + H Q Q+Q QRLQ QQ+ LQ Q+ + QQ++Q+ + + QQ +Q Sbjct: 148 PELQLMHQQQQLQPQQVQ-EQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQE-QQLLQ 205 Query: 1201 QHQRQLAQALLVKQ 1214 Q Q QL Q L++Q Sbjct: 206 QQQEQLQQQQLLQQ 219 Score = 46.6 bits (109), Expect = 2e-04 Identities = 47/138 (34%), Positives = 59/138 (42%), Gaps = 16/138 (11%) Query: 1086 QARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINP 1145 Q +QQ Q Q L Q L+ Q Q L Q Q Q QF + L Sbjct: 190 QQEQLQQQVQEQ-QLLQQQQEQLQQQ--QLLQQQEQLQQQQFQQQQEQLQ--------QQ 238 Query: 1146 QHMTMLNQLYQLQ---LAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQH 1202 Q + +L Q QLQ L Q+ Q+QQQ+L+ Q+ +QQ QQ +QQ Sbjct: 239 QQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQ 298 Query: 1203 QRQLAQALLVKQPPPPPP 1220 Q QL Q L QPPP P Sbjct: 299 QEQLQQQQL--QPPPLEP 314 Score = 41.6 bits (96), Expect = 0.007 Identities = 45/143 (31%), Positives = 60/143 (41%), Gaps = 10/143 (6%) Query: 1086 QARTMQQPPQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLTSPIN 1144 Q + Q Q Q + Q L+ QV Q L Q Q QL Q + + L Sbjct: 172 QQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQ---QQLLQQQEQLQQQQF 228 Query: 1145 PQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQR 1204 Q L Q QL L Q+ Q+QQQ+LQ Q+ ++QQ L QQ +Q Q+ Sbjct: 229 QQQQEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQ 288 Query: 1205 QLAQALL------VKQPPPPPPP 1221 Q Q LL ++Q PPP Sbjct: 289 QQQQQLLQQQQEQLQQQQLQPPP 311 Score = 40.0 bits (92), Expect = 0.019 Identities = 54/192 (28%), Positives = 75/192 (39%), Gaps = 16/192 (8%) Query: 1024 LVEEPTPSPFLPSPSLKLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNSG 1083 L ++P P L+ P H L Q G Q L+ +Q ++ Sbjct: 94 LEQQPEPQQQPQHEQLQQPQPHLELQQQPQQD-----GQQQLSQLQQEKHQSVHHQELKP 148 Query: 1084 AAQARTMQQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPI 1143 Q QQ QP Q L+ Q Q + Q Q Q Q + L + + Sbjct: 149 ELQLMHQQQQLQPQQV---QEQQRLQQQQEQLQTQQAQEQ--QVLQQQEQLQQQVQEQQL 203 Query: 1144 NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQI-QQH 1202 Q QL Q QL Q+ Q+QQQ Q Q+ +QQ+ + + LQQQ+ QQ Sbjct: 204 LQQQQ---EQLQQQQLLQQQEQLQQQQFQQQQEQL--QQQQQLLLLQQQGQLQQQLLQQQ 258 Query: 1203 QRQLAQALLVKQ 1214 Q QL Q LL +Q Sbjct: 259 QAQLQQQLLEQQ 270 Score = 39.3 bits (90), Expect = 0.033 Identities = 46/156 (29%), Positives = 63/156 (40%), Gaps = 19/156 (12%) Query: 1091 QQPPQPPVQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPA------LLTSPIN 1144 QQ Q Q L Q L+ Q Q L Q Q QL Q + L P L P++ Sbjct: 269 QQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVD 328 Query: 1145 PQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQR 1204 L Q Q Q L+ QQ+ Q Q + ++Q EQQ+ + QQQ++Q + Sbjct: 329 LGSEQELEQQRQELERQQELERQQEQRQLQLKLQEELQQLEQQLEQQ----QQQLEQQEV 384 Query: 1205 QL---------AQALLVKQPPPPPPPPHLSLHPSAG 1231 QL Q + + P P L L P+AG Sbjct: 385 QLELTPVELGAQQQEVQLELTPVQPELQLELVPAAG 420 >gi|33286444 mastermind-like 2 [Homo sapiens] Length = 1156 Score = 52.4 bits (124), Expect = 4e-06 Identities = 66/236 (27%), Positives = 93/236 (39%), Gaps = 26/236 (11%) Query: 1028 PTPSPF----LPSPSL-KLPLSHSALPSQALGGIASGLGMQNLNSSRQIPSGNLGMFGNS 1082 P+P PF +PSPS + S + P + G+A G G + ++ +G G+ Sbjct: 470 PSPGPFGQEKIPSPSFGQQTFSPQSSP---MPGVAGGSGQSKVMANYMYKAGPSAQGGHL 526 Query: 1083 GAAQARTMQQPPQPPVQP-LNSSQPSLRAQV----PQFLSPQVQAQLLQFAAKNIGLNPA 1137 MQQ PQ + +N+ P++ + P F QA + P+ Sbjct: 527 DVL----MQQKPQDLSRSFINNPHPAMEPRQGNTKPLFHFNSDQANQQMPSVLPSQNKPS 582 Query: 1138 LLTSPINPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQ 1197 LL Q Q Q Q Q+ Q QQQ Q Q+ S S +QQ+QQ + QQ Sbjct: 583 LLHYTQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQ 642 Query: 1198 QIQQHQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHPQTPGLPDLQTK 1253 Q QQ Q+Q Q +Q P S P+ S PS P LQ K Sbjct: 643 QQQQQQQQQQQQQQQQQQQQQQQP---SSQPA------QSLPSQPLLRSPLPLQQK 689 >gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens] Length = 1745 Score = 52.4 bits (124), Expect = 4e-06 Identities = 69/257 (26%), Positives = 84/257 (32%), Gaps = 43/257 (16%) Query: 214 MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTV 273 +G I PP LQGLPG G +V + G + P P G G G Sbjct: 1141 VGVIGPPGLQGLPGPPGEK-GEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGGVGQP- 1198 Query: 274 NSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSR 333 AV ++G G+A D GPP PGI G G SGA G P + Sbjct: 1199 ------------GAVGEKGERGDAGDPGPPGAPGIPGPKGDIGEKGDSG-PSGAAGPPGK 1245 Query: 334 STSNGVNGEWGK-----------PPNQHSNSDINGK-------GSTGWESPSVTSQNPTV 375 G +G G PP S I+G G G P S P Sbjct: 1246 KGPPGEDGAKGSVGPTGLPGDLGPPGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305 Query: 376 QPGGEHMNSWAKAASSGTTASEGSSDGSGNHNE----GSTGREGTGEGRRRDKGIIDQGH 431 PG K SG EG G E G GR G R + +G Sbjct: 1306 -PGPP-----GKRGPSGHMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGL 1359 Query: 432 IQLPRNDLDPRVLSNTG 448 +P +P +L G Sbjct: 1360 RGIPGPVGEPGLLGAPG 1376 Score = 41.6 bits (96), Expect = 0.007 Identities = 60/243 (24%), Positives = 77/243 (31%), Gaps = 52/243 (21%) Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVG-MGAIIPPHLQGLPGANGSSVSQVSGGSA 241 GP P P+ A NG P +G G I P G G G + + S G Sbjct: 989 GPTGLKGDKGPPGPVGA---NGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRGER 1045 Query: 242 --------EGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGS 293 +GI + L P A + G G A +GS Sbjct: 1046 GPPGPTGKDGIPGPLGPLGPPGAAGPSGEEG----------------DKGDVGAPGHKGS 1089 Query: 294 GGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNS 353 G+ D+GPP PGI G GHP ++G G G P Sbjct: 1090 KGDKGDAGPPGQPGI----------------RGPAGHPGPPGADGAQGRRGPPGLFGQKG 1133 Query: 354 DINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGSGNHNEGSTGR 413 D +G G P P P GE + G+ G+ G +G TG Sbjct: 1134 DDGVRGFVGVIGPPGLQGLP--GPPGEK----GEVGDVGSMGPHGAPGPRG--PQGPTGS 1185 Query: 414 EGT 416 EGT Sbjct: 1186 EGT 1188 Score = 40.8 bits (94), Expect = 0.011 Identities = 44/166 (26%), Positives = 56/166 (33%), Gaps = 15/166 (9%) Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAE 242 GP SP P G+ G G + PP G PG G+ SQ G Sbjct: 599 GPRGLLGPRGSPGPTGRPGVTGID--GAPGAKGNVGPPGEPGPPGQQGNHGSQGLPGPQG 656 Query: 243 GISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGP 302 I PGNP G +G + G ++G+ G +GP Sbjct: 657 LIGTPGEKGPPGNPGI----PGLPGSDGPLGHP-------GHEGPTGEKGAQGPPGSAGP 705 Query: 303 PAGPGILAWGRGSGNNGVGNI--HSGAWGHPSRSTSNGVNGEWGKP 346 P PG SGN G+ G G P G+ G+ GKP Sbjct: 706 PGYPGPRGVKGTSGNRGLQGEKGEKGEDGFPGFKGDVGLKGDQGKP 751 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 51.6 bits (122), Expect = 6e-06 Identities = 142/612 (23%), Positives = 199/612 (32%), Gaps = 107/612 (17%) Query: 113 GHEGTVATGNPSSICSPVSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSF 172 G +G+V P+ P+ + G P G +GA GN P P+ Sbjct: 235 GSDGSVGPVGPAG---PIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEVGL---- 287 Query: 173 SAQPQNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSS 232 P + P+ NP NGL A G+ + GLPG G Sbjct: 288 -----------PGLSGPVGPPGNP----GANGLTGAKGAAGLPGVAGA--PGLPGPRGIP 330 Query: 233 VSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG 292 V A G V G P G + S GN SA G S K G Sbjct: 331 -GPVGAAGATGARGLV-----GEP--GPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG 382 Query: 293 SGGNAWDSGPPAGPGILAWGRGS-GNNGV--GNIHSGAWGHP-SRSTS-----NGVNGEW 343 G A +GPP PG+ RGS G+ G+ + +G G P SR S G NG+ Sbjct: 383 PNGEAGSAGPPGPPGL----RGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438 Query: 344 GKP-----------PNQHSNSDINGK-GSTGWESPSVTSQNPTVQPGGE--HMNSWAKAA 389 G+P P N GK G G P + + + P G + Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG--LPGIDGRPGPIGPAGARGEPGNIGFPG 496 Query: 390 SSGTTASEGSSDGSGNHN----------EGSTGREGTGEGRRRDKGIIDQGHIQLPRNDL 439 G T G + G+ +G+ G +G + G +QG P Sbjct: 497 PKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQG 556 Query: 440 DPRVLSNTGWGQTPVKQNTAWEF----EESPRSERKNDNGTEAWGCAATQASN------- 488 P G P ++ EF PR ER + A G S Sbjct: 557 LPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPG 616 Query: 489 -SGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTG-WGDSNNKAPSG-PGVWGD--SISS 543 G K + ++ + T+ SG P+ +P G G K G PG+ G+ + Sbjct: 617 PDGNKGEPGVVGAVGTAGPSG-----PSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGR 671 Query: 544 TAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSS 603 A A +GA ++ G P P G+R AG +A + Sbjct: 672 DGARGAPGAVGAPGPAGATGDRGEAGAAG-PAGPAGPRGSPGERGE-VGPAGPNGFAGPA 729 Query: 604 SVLGHLG-DGKKNGSGWDADSNRSG----------SGWNDTT-RSGNSGWGNSTNTKANP 651 G G G++ G ++ G +G N +G+ G G P Sbjct: 730 GAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFP 789 Query: 652 GTNWGETLKPGP 663 G G T PGP Sbjct: 790 GAA-GRTGPPGP 800 Score = 51.2 bits (121), Expect = 8e-06 Identities = 98/423 (23%), Positives = 132/423 (31%), Gaps = 36/423 (8%) Query: 14 TKKTNGNNGTNGAL-VQSPSNQSAL-GAGGANSNGSAARVWGVATGSSSGLAHCSVSGGD 71 +K +GN G G+ Q P S G G N +A G G + G D Sbjct: 353 SKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPG-PPGLRGSPGSRGLPGAD 411 Query: 72 GKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS 131 G+ M G S+ G + G N + P G G+ P+ PV Sbjct: 412 GRAGVM-GPPGSRGASGPAGVR-GPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVG 469 Query: 132 AIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQN--VSFSAQPQNLNTDGPNNTNP 189 G + P G G GN+ P +N + GP+ N Sbjct: 470 LPGIDGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNG 529 Query: 190 MNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVW 249 P P G G PP QGLPG +G + +V G+ Sbjct: 530 AQGPPGPQGVQGGKG--------EQGPPGPPGFQGLPGPSGPA-GEVGKPGERGLHGEFG 580 Query: 250 GLSPGNPATGNSNSGFSQGNGDTVNSALSAKQN--------GSSSAVQKEGSGGNAWDSG 301 P P G S G T G V G+ G + SG Sbjct: 581 LPGPAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSG 640 Query: 302 PPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGST 361 P G G G G + G G+P R + G G G P + D G+ Sbjct: 641 LPGERGAAGIPGGKGEKGEPGLR-GEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAA 699 Query: 362 GWESPSVTSQNP----TVQPGGEHMNSWA-KAASSGTTASEGSSDGSGNHNE----GSTG 412 G P+ +P V P G N +A A ++G ++G G E G TG Sbjct: 700 GPAGPAGPRGSPGERGEVGPAGP--NGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTG 757 Query: 413 REG 415 G Sbjct: 758 PVG 760 Score = 48.5 bits (114), Expect = 5e-05 Identities = 64/253 (25%), Positives = 86/253 (33%), Gaps = 32/253 (12%) Query: 183 GPNNTNPMNSSPNPINAMQTNGLPNW--GMAVGMGAIIPPHLQGLPGANGSSVSQVSGGS 240 GP N + P+ A G PN G A G PP + G PGA G + Sbjct: 745 GPKGENGVVGPTGPVGAAGPAG-PNGPPGPAGSRGDGGPPGMTGFPGAAG----RTGPPG 799 Query: 241 AEGISNSVWGLSPGNPA-TGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWD 299 GIS PG P G +G+ V G ++G G A Sbjct: 800 PSGISGP-----PGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGT 854 Query: 300 SGPP---------AGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKPPNQH 350 +GPP PGIL G G+ + +GA G P G G G PP Sbjct: 855 AGPPGTPGPQGLLGAPGILGLPGSRGERGLPGV-AGAVGEPGPLGIAGPPGARG-PPGAV 912 Query: 351 SNSDING-------KGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTTASEGSSDGS 403 + +NG G+ G + P P + + + ++G G + Sbjct: 913 GSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPA 972 Query: 404 GNH-NEGSTGREG 415 G H N G TG G Sbjct: 973 GKHGNRGETGPSG 985 Score = 43.9 bits (102), Expect = 0.001 Identities = 61/218 (27%), Positives = 78/218 (35%), Gaps = 18/218 (8%) Query: 220 PHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALSA 279 P +G+ G NG + G A G+ G N G + + G V + A Sbjct: 174 PGFKGIRGHNGLDGLKGQPG-APGVKGEP-GAPGENGTPGQTGARGLPGERGRVGAPGPA 231 Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNI-HSGAWGHPSRSTSNG 338 GS +V G G +GPP PG A G VGN +G G G Sbjct: 232 GARGSDGSVGPVGPAGPIGSAGPPGFPG--APGPKGEIGAVGNAGPAGPAGPRGEVGLPG 289 Query: 339 VNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGEHMNSWAKAASS-----GT 393 ++G G P N +N KG+ G P V P G A A+ G Sbjct: 290 LSGPVGPPGNPGANGLTGAKGAAG--LPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGE 347 Query: 394 TASEGSSDGSGNHNE-GSTGREGT-----GEGRRRDKG 425 GS SGN E GS G +G EG+R G Sbjct: 348 PGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNG 385 Score = 41.6 bits (96), Expect = 0.007 Identities = 49/174 (28%), Positives = 61/174 (35%), Gaps = 15/174 (8%) Query: 204 GLPNWGMAVG----MGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPAT- 258 GLP AVG +G PP +G PGA GS + G A N PG Sbjct: 883 GLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQP 942 Query: 259 GNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNN 318 G+ GN V +A + +G K G+ G SGP G + SG Sbjct: 943 GHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGPSGPQ 1002 Query: 319 GVGNIHSGAWGHPSRSTSNGV------NGEWGKPPNQHSNSDINGKGSTGWESP 366 G+ G G P G+ NG G P + D GS G P Sbjct: 1003 GI----RGDKGEPGEKGPRGLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGP 1052 Score = 35.8 bits (81), Expect = 0.36 Identities = 49/213 (23%), Positives = 69/213 (32%), Gaps = 18/213 (8%) Query: 219 PPHLQGLPGANGSSVSQVSGGSAEGISNSVWGLSPGNPATGNSNSGFSQGNGDTVNSALS 278 PP G PG G+ +Q G G+ GL G + + QG Sbjct: 64 PPGPPGPPGLGGNFAAQYDGKGV-GLGPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGE 122 Query: 279 AKQNGSSSAVQKEGSGGNAWDSGPPAGP------GILAWGRGSGNNGVGNI--------H 324 Q G + A G G A + G P P G++ G G + H Sbjct: 123 PGQTGPAGARGPAGPPGKAGEDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGH 182 Query: 325 SGAWGHPSRSTSNGVNGEWGKPPNQHSNSDINGKGSTGWESPSVTSQNPTVQPGGE-HMN 383 +G G + + GV GE G P + +G G E V + P G + + Sbjct: 183 NGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPG-ERGRVGAPGPAGARGSDGSVG 241 Query: 384 SWAKAASSGTTASEGSSDGSGNHNE-GSTGREG 415 A G+ G G E G+ G G Sbjct: 242 PVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAG 274 Score = 33.9 bits (76), Expect = 1.4 Identities = 75/312 (24%), Positives = 97/312 (31%), Gaps = 50/312 (16%) Query: 15 KKTNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGV-----ATGSSSGLAHCSVSG 69 K +G GT G +P Q LGA G + G+ A G L G Sbjct: 846 KGPSGEAGTAGP-PGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPG 904 Query: 70 GDGKMDTMIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSP 129 G + G + + AG + N + P GH+G G P +I P Sbjct: 905 ARGPPGAVGSPGVN-----GAPGEAGRDGNPGNDGPPGRDGQPGHKGE--RGYPGNI-GP 956 Query: 130 VSAIGQNMGNQNGNPTGTLGAWGNLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNP 189 V A G + P G G G P P + GP+ Sbjct: 957 VGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPR-------------GPSGPQG 1003 Query: 190 MNSSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVW 249 + GLP G+ G LQGLPG G Q G SV Sbjct: 1004 IRGDKGEPGEKGPRGLP--GLKGHNG------LQGLPGIAGHHGDQ-------GAPGSVG 1048 Query: 250 GLSPGNPA--TGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEGSGGNAWDSGPPAGPG 307 P PA +G + G+ TV A G +G G GPP PG Sbjct: 1049 PAGPRGPAGPSGPAGKDGRTGHPGTVGPA------GIRGPQGHQGPAGPPGPPGPPGPPG 1102 Query: 308 ILAWGRGSGNNG 319 + G G +G Sbjct: 1103 VSGGGYDFGYDG 1114 >gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo sapiens] Length = 2134 Score = 51.6 bits (122), Expect = 6e-06 Identities = 101/452 (22%), Positives = 150/452 (33%), Gaps = 79/452 (17%) Query: 251 LSPGNPATGNSNSGFSQGNGDTVNSALSAKQNGSSSAVQKEG-----SGGNAWDSGPPAG 305 L G P+T S + + +T + L ++ + + + GNA +G + Sbjct: 1705 LVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAGMTGVVSP 1764 Query: 306 PGILAWGRGSGNNGVGNIHSGAWGHPS--RSTSNGVNGEW-----GKPPNQHSNSDINGK 358 A G GV +GA + R+ + V+GE G P + G Sbjct: 1765 TVTGASGMAGTTGGVDAATTGAASENTSERAGTPRVSGETPAVGGGSTPGEA------GP 1818 Query: 359 GSTGWESPSVTSQNPTVQPGGEHMNSWAKAASSGTT-----ASEGSSDGSGNHNEGSTGR 413 G+T S V++ + T PG +S +++ SGTT G++ +EG +G Sbjct: 1819 GATVSGSTGVSAGSITASPGASATSS--ESSKSGTTGPSVGGKTGATSSEATSSEGMSGV 1876 Query: 414 EGTGEGRRRDKGIIDQGHIQLPRNDLDPRVLSNTGW-GQTPVKQNTAWEFEESPRSERKN 472 G G D + + T + G +P + T SP S Sbjct: 1877 TGQSLGSTAGS---------------DSEITAKTSFTGSSPPGKLT----RPSPGSPGHF 1917 Query: 473 DNGTEAWGCAATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPS 532 GT WG AT + + G+N + ST S V A T G N S Sbjct: 1918 SGGTTEWGNVAT--TGAAGENTSGALGSTEGS------------VEATTSAGSGNTAGTS 1963 Query: 533 GPGVWGDSISSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAW 592 G G G +TAVS G P P S G+ N ++ Sbjct: 1964 GTGDTGP--GNTAVSGTPVVSPG----------------ATPGAPGSSTPGEADIGNTSF 2005 Query: 593 SAGGGDWADSSSVLGHLGDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPG 652 G DS +VL + A S S T + + S + PG Sbjct: 2006 GKSGKSGHDSLTVLNPA--FLRRTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPG 2063 Query: 653 TNWGETLKPGPQQNWASKPQDNNVSNWGGAAS 684 T G T W+S SN G S Sbjct: 2064 TPGGATSGGKITSGWSSSGTSTGASNTPGEIS 2095 Score = 48.5 bits (114), Expect = 5e-05 Identities = 85/377 (22%), Positives = 134/377 (35%), Gaps = 51/377 (13%) Query: 17 TNGNNGTNGALVQSPSNQSALGAGGANSNGSAARVWGVATGSSSGLAHCSVSGGDGKMDT 76 T+GN G G V SP+ A G G AA + +S VSG +T Sbjct: 1752 TSGNAGMTG--VVSPTVTGASGMAGTTGGVDAATTGAASENTSERAGTPRVSG-----ET 1804 Query: 77 MIGDGRSQNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS-AIGQ 135 G G++ AG ++ + +A + G AT + SS ++G Sbjct: 1805 PAVGG------GSTPGEAGPGATVSGSTGVSAGSITASPGASATSSESSKSGTTGPSVGG 1858 Query: 136 NMGNQNGNPTGTLGAWG----NLLPQESTEPQTSTSQNVSFSAQPQNLNTDGPNNTNPMN 191 G + T + G G +L ++ + + + + S+ P L T P Sbjct: 1859 KTGATSSEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKL-------TRPSP 1911 Query: 192 SSPNPINAMQTNGLPNWGMAVGMGAIIPPHLQGLPGANGSSVSQVSGGSAEGISNSVWGL 251 SP + G WG GA G N S + GS E +++ G Sbjct: 1912 GSPGHFSG----GTTEWGNVATTGAA---------GENTSGALGSTEGSVEATTSAGSGN 1958 Query: 252 SPGNPATGNSNSGFSQGNG-DTVNSALSAKQNGSSSAVQKE-------GSGGNAWDSGPP 303 + G TG++ G + +G V+ + GSS+ + + SG + DS Sbjct: 1959 TAGTSGTGDTGPGNTAVSGTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTV 2018 Query: 304 AGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGVNGEWGKP--PNQHSNSDINGKGST 361 P L R + S H +++ V KP P + GK ++ Sbjct: 2019 LNPAFLR--RTPTVSAASTTSSPVSKHTDAASATAVTISGSKPGTPGTPGGATSGGKITS 2076 Query: 362 GWESPSVTSQNPTVQPG 378 GW S S TS + PG Sbjct: 2077 GWSS-SGTSTGASNTPG 2092 Score = 42.4 bits (98), Expect = 0.004 Identities = 91/394 (23%), Positives = 125/394 (31%), Gaps = 54/394 (13%) Query: 482 AATQASNSGGKNDGSIMNSTNTSSVSGWVNAPPAAVPANTGWGDSNNKAPSGPGVWGDSI 541 AA G SI T +SS + P P TG +++ S G G Sbjct: 1701 AAITLVTGGPSTAASIPAITTSSSETTGTTLGPLTEPFTTGITETSVPIISTSGNAG--- 1757 Query: 542 SSTAVSTAAAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWAD 601 + VS SG A G D + T G + S+ G + S + GGG Sbjct: 1758 MTGVVSPTVTGASGMA--GTTGGVDAATT-GAASENTSERAGTPRVSGETPAVGGG---- 1810 Query: 602 SSSVLGHLGDGK--KNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETL 659 S G G G +G A S + G + T+ + S T + G G T Sbjct: 1811 --STPGEAGPGATVSGSTGVSAGSITASPGASATSSESSK----SGTTGPSVGGKTGATS 1864 Query: 660 KPGPQQNWASKPQDNNVSNWGGAASVKQTGTGWIGGPVPVKQKDSSEATGWEEPSPPSIR 719 S ++ + G+ S T + G P K PSP S Sbjct: 1865 SEATSSEGMSGVTGQSLGSTAGSDSEITAKTSFTGSSPPGKLT---------RPSPGS-- 1913 Query: 720 RKMEIDDGTSAWGDPSNYNNKTVNMWDRNNPVIQSSTTTNTTTTTTTTTSNTTHRVETPP 779 GT+ WG N T N ST + TT+ + NT T Sbjct: 1914 -PGHFSGGTTEWG-----NVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAGTSGTGD 1967 Query: 780 PHQAGTQLNRSPLLGPGRKVSSGWGEMPNVHSKTENSWGEPSSPSTLVDNGTAAWGKPPS 839 T ++ +P++ PG + P GE D G ++GK S Sbjct: 1968 TGPGNTAVSGTPVVSPGATPGAPGSSTP----------GE-------ADIGNTSFGK--S 2008 Query: 840 SGSGWGDHPAEPPVAFGRAGAPVAASALCKPASK 873 SG P R AAS P SK Sbjct: 2009 GKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSK 2042 Score = 32.3 bits (72), Expect = 4.0 Identities = 34/148 (22%), Positives = 56/148 (37%), Gaps = 14/148 (9%) Query: 550 AAAKSGHAWSGAANQEDKSPTWGEPPKPKSQHWGDGQRSNPAWSAGGGDWADSSSVLGHL 609 A KSG + ++ + +P G S GD + P +S G + Sbjct: 108 AEDKSGDSQDAGGSKSEDTPPGGFFYGSSSS--GDSDKKKPLFSFEFGATGE-------- 157 Query: 610 GDGKKNGSGWDADSNRSGSGWNDTTRSGNSGWGNSTNTKANPGTNWGETLKPGPQQNWAS 669 D K+ WDA ++RS D+T + +S+ + G WG + + G + + A Sbjct: 158 -DEDKSRERWDAGNSRSEDSPADSTNTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKAD 216 Query: 670 KPQDNNVSNWGGAASV---KQTGTGWIG 694 + + GG V GTG G Sbjct: 217 GRETRGSGSAGGETIVFGPDAVGTGSSG 244 Score = 31.6 bits (70), Expect = 6.8 Identities = 81/393 (20%), Positives = 128/393 (32%), Gaps = 55/393 (13%) Query: 22 GTNGALVQSPSNQSALGAGGANSNG------SAARVWGVATGSSSGLAHCSVSGGDGKMD 75 G++G + + +A G ++SN S+ V G T SS G + + + Sbjct: 241 GSSGLKLGAGKGDAAFGFEVSDSNSFGDTGISSKTVEGNQTSSSGGSVSIDLGDTSFRSE 300 Query: 76 TMIGDGRS----QNCWGASNSNAGINLNLNPNANPAAWPVLGHEGTVATGNPSSICSPVS 131 G S N W + GIN N + V G G+ SS S Sbjct: 301 NQFVGGGSLNSISNLWDSGQEGFGIN---EIGGNGMSGSVSAEAGFKGFGSDSS-----S 352 Query: 132 AIGQNMGNQNGNPTGTLGAW------------GNLLPQESTEPQTSTS-----QNVSFSA 174 ++G + G +GA GN L + + +S +N+ F Sbjct: 353 SVGMLESLEFGLGGKKVGAGFDFKYSGSRKFGGNELSENGIKVTRESSSSDLAENLGFGL 412 Query: 175 QP---QNLNTDGPNNTNPMNSSPNPINAMQTNGLPNWGMAVGMGAI---IPPHLQGLPGA 228 + + T G +S + A++ + L +G+ G G Sbjct: 413 EKFGQKGFGTSGSGWNEQSSSKSDVSGAVEKSWLFEFGLGETKGGAEFNFRDSGSNQSGD 472 Query: 229 NGSSVSQVSGGSA------EGISNSVWGLSPGNPATGNSNSG---FSQGNGDTVNSALSA 279 NG+S G G NS G+S+ S+ G+ S+ Sbjct: 473 NGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGGNRKRSSDPD 532 Query: 280 KQNGSSSAVQKEGSGGNAWDSGPPAGPGILAWGRGSGNNGVGNIHSGAWGHPSRSTSNGV 339 + S SGGN W S +G G G+ + GVG +G S S Sbjct: 533 EAGNLSPGSDVSDSGGNTWSSDSGSGGG----GKSADELGVGASGLNEFGETGLSGSEKG 588 Query: 340 NGEWGKPPNQHSNSDINGKGSTGWESPSVTSQN 372 + P + I G+ ST W + S N Sbjct: 589 SHIPEATPKYSETNAIIGEIST-WSKGAYKSFN 620 >gi|93141033 PAX interacting protein 1 [Homo sapiens] Length = 1069 Score = 50.8 bits (120), Expect = 1e-05 Identities = 50/169 (29%), Positives = 66/169 (39%), Gaps = 16/169 (9%) Query: 1086 QARTMQQP-PQPPVQPLNSSQPSLRAQVP-QFLSPQVQAQLLQFAAKNIGLNPALLTSPI 1143 Q + QQP PQ P P + Q + P QF Q+Q Q P P Sbjct: 432 QQQISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQLHPPQQLHRPQQQLQPF 491 Query: 1144 NPQHMTMLNQLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVART-ITNLQQQIQQ- 1201 QH + Q +QLQ Q QQQ+ Q Q+ S +QQ+QQ+ + + + QQ QQ Sbjct: 492 QQQH-ALQQQFHQLQ---QHQLQQQQLAQLQQQHSLLQQQQQQQIQQQQLQRMHQQQQQQ 547 Query: 1202 --------HQRQLAQALLVKQPPPPPPPPHLSLHPSAGKSAMDSFPSHP 1242 H Q +QAL + PP PP P F P Sbjct: 548 QMQSQTAPHLSQTSQALQHQVPPQQPPQQQQQQQPPPSPQQHQLFGHDP 596 Score = 37.4 bits (85), Expect = 0.12 Identities = 50/208 (24%), Positives = 79/208 (37%), Gaps = 22/208 (10%) Query: 1042 PLSHSALPSQALGGI-ASGLGMQNLNSSRQIPSGNLGMFGNSGAAQARTMQQPPQPP--- 1097 P+ + LP + G + A+G +Q+ S I + + + +QQ +P Sbjct: 298 PVPGNILPPEVRGNLMAAGQNLQSSERSEMIATWSPAVRTLRNITNNADIQQMNRPSNVA 357 Query: 1098 --VQPLNSSQPSLRAQVPQFLSPQVQAQLLQFAAKNIGLNPALLTSPINPQHMTMLN--- 1152 +Q L++ +L QV A + F+ + +L Q + Sbjct: 358 HILQTLSAPTKNLEQQVNHSQQGHTNANAVLFSQVKVTPETHMLQQQQQAQQQQQQHPVL 417 Query: 1153 -----QLYQLQLAYQRLQIQQQMLQAQRNVSGSMRQQEQQVARTITNLQQQIQQHQRQLA 1207 Q+ QLQ Q+ QI QQ Q S +QQ+QQ A QQQ+Q Q+QL Sbjct: 418 HLQPQQIMQLQQQQQQ-QISQQPYPQQPPHPFSQQQQQQQQAHPHQFSQQQLQFPQQQL- 475 Query: 1208 QALLVKQPPPPPPPPHLSLHPSAGKSAM 1235 PP P L P + A+ Sbjct: 476 ------HPPQQLHRPQQQLQPFQQQHAL 497 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.306 0.125 0.383 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 83,959,850 Number of Sequences: 37866 Number of extensions: 4899062 Number of successful extensions: 29793 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 158 Number of HSP's successfully gapped in prelim test: 787 Number of HSP's that attempted gapping in prelim test: 18337 Number of HSP's gapped (non-prelim): 7428 length of query: 1690 length of database: 18,247,518 effective HSP length: 116 effective length of query: 1574 effective length of database: 13,855,062 effective search space: 21807867588 effective search space used: 21807867588 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.