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Search of human proteins with 33188431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo
sapiens]
(1347 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sap... 2760 0.0
gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sap... 2544 0.0
gi|189011544 ubiquitously transcribed tetratricopeptide repeat, ... 2344 0.0
gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo sap... 2022 0.0
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 697 0.0
gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens] 55 3e-07
gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens] 55 3e-07
gi|118402596 cell division cycle protein 23 [Homo sapiens] 54 8e-07
gi|161016767 mucin 21 [Homo sapiens] 52 3e-06
gi|224809432 transmembrane and tetratricopeptide repeat containi... 51 7e-06
gi|7661950 SH2 domain binding protein 1 [Homo sapiens] 51 9e-06
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 50 1e-05
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 50 1e-05
gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens] 49 4e-05
gi|118766328 transmembrane and tetratricopeptide repeat containi... 47 1e-04
gi|118766330 transmembrane and tetratricopeptide repeat containi... 47 1e-04
gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens] 47 1e-04
gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens] 47 2e-04
gi|167466177 cell division cycle protein 27 isoform 1 [Homo sapi... 45 6e-04
gi|167466175 cell division cycle protein 27 isoform 2 [Homo sapi... 45 6e-04
gi|89026265 PREDICTED: mucin 12 [Homo sapiens] 42 0.004
gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens] 41 0.007
gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo sa... 41 0.007
gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo sa... 41 0.007
gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo sa... 41 0.007
gi|151301154 mucin 6, gastric [Homo sapiens] 41 0.007
gi|60097902 filaggrin [Homo sapiens] 41 0.009
gi|22749211 transmembrane and tetratricopeptide repeat containin... 40 0.012
gi|239754668 PREDICTED: mucin 12 [Homo sapiens] 40 0.015
gi|83415184 transmembrane and tetratricopeptide repeat containin... 40 0.020
>gi|33188431 tetratricopeptide repeat protein isoform 3 [Homo sapiens]
Length = 1347
Score = 2760 bits (7155), Expect = 0.0
Identities = 1347/1347 (100%), Positives = 1347/1347 (100%)
Query: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
Sbjct: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
Query: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
Sbjct: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
Query: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
Sbjct: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
Query: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
Sbjct: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
Query: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
Sbjct: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
Query: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
Sbjct: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
Query: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
Sbjct: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
Query: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
Sbjct: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
Query: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
Sbjct: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
Query: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
Sbjct: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
Query: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
Sbjct: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
Query: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
Sbjct: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
Query: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
Sbjct: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
Query: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
Sbjct: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
Query: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
Sbjct: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
Query: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
Sbjct: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
Query: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR 1020
PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
Sbjct: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR 1020
Query: 1021 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ 1080
RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
Sbjct: 1021 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ 1080
Query: 1081 LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW 1140
LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW
Sbjct: 1081 LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW 1140
Query: 1141 WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV 1200
WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV
Sbjct: 1141 WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV 1200
Query: 1201 ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAA 1260
ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAA
Sbjct: 1201 ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAA 1260
Query: 1261 GKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFV 1320
GKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFV
Sbjct: 1261 GKEVIWHGRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFV 1320
Query: 1321 VLEQYKMEDLIQVYDQFTLALSLSSSS 1347
VLEQYKMEDLIQVYDQFTLALSLSSSS
Sbjct: 1321 VLEQYKMEDLIQVYDQFTLALSLSSSS 1347
>gi|33188427 tetratricopeptide repeat protein isoform 2 [Homo sapiens]
Length = 1240
Score = 2545 bits (6595), Expect = 0.0
Identities = 1240/1240 (100%), Positives = 1240/1240 (100%)
Query: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
Sbjct: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
Query: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
Sbjct: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
Query: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
Sbjct: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
Query: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
Sbjct: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
Query: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
Sbjct: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
Query: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
Sbjct: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
Query: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
Sbjct: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
Query: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
Sbjct: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
Query: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
Sbjct: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
Query: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
Sbjct: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
Query: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
Sbjct: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
Query: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
Sbjct: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
Query: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
Sbjct: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
Query: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
Sbjct: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
Query: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
Sbjct: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
Query: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
Sbjct: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
Query: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR 1020
PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR
Sbjct: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGR 1020
Query: 1021 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ 1080
RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ
Sbjct: 1021 RRKGPFKTIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQ 1080
Query: 1081 LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW 1140
LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW
Sbjct: 1081 LYMKVPGSRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSW 1140
Query: 1141 WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV 1200
WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV
Sbjct: 1141 WPNLEDLYEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAV 1200
Query: 1201 ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIK 1240
ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIK
Sbjct: 1201 ERYEWNKLKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIK 1240
>gi|189011544 ubiquitously transcribed tetratricopeptide repeat, X
chromosome [Homo sapiens]
Length = 1401
Score = 2344 bits (6075), Expect = 0.0
Identities = 1166/1400 (83%), Positives = 1232/1400 (88%), Gaps = 53/1400 (3%)
Query: 1 MKSCAVSLTTAAVA---FGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFV 57
MKSC VSL TAA A FGDE KKMA GKAS ESEE S SLT EEREALGG+DSRLFGFV
Sbjct: 1 MKSCGVSLATAAAAAAAFGDEEKKMAAGKASGESEEASPSLTAEEREALGGLDSRLFGFV 60
Query: 58 RLHEDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYY 117
R HEDGARTK LLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDY KALSAYQRYY
Sbjct: 61 RFHEDGARTKALLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYPKALSAYQRYY 120
Query: 118 SLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVN 177
SLQ+DYWKNAAFLYGLGLVYF+YNAF WAIKAFQ+VLYVDPSFCRAKEIHLRLGLMFKVN
Sbjct: 121 SLQSDYWKNAAFLYGLGLVYFHYNAFQWAIKAFQEVLYVDPSFCRAKEIHLRLGLMFKVN 180
Query: 178 TDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQ 237
TDY+SSLKHFQLAL+DCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENL AQ
Sbjct: 181 TDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLSAQ 240
Query: 238 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 297
VKATVLQQLGWMHH +DL+GDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV
Sbjct: 241 VKATVLQQLGWMHHTVDLLGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKV 300
Query: 298 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 357
QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT
Sbjct: 301 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 360
Query: 358 LYESCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQ---------------------- 395
LYESCNQPQDAIKCYLNA RSK CSNTS LAARIK+LQ
Sbjct: 361 LYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQAQLCNLPQGSLQNKTKLLPSIE 420
Query: 396 -----------------------NGSDNWNGGQSLSHHPVQQ-VYSLCLTPQKLQHLEQL 431
N SDNW+GG ++SH PVQQ +S CLTPQKLQHLEQL
Sbjct: 421 EAWSLPIPAELTSRQGAMNTAQQNTSDNWSGGHAVSHPPVQQQAHSWCLTPQKLQHLEQL 480
Query: 432 RANRDNLNPAQKHQLEQLESQFVLMQQ--MRHKEVAQVRTTGIHNGAITDSSLPTNSVSN 489
RANR+NLNPAQK LEQLESQFVLMQQ MR VAQVR+TGI NG DSSLPTNSVS
Sbjct: 481 RANRNNLNPAQKLMLEQLESQFVLMQQHQMRPTGVAQVRSTGIPNGPTADSSLPTNSVSG 540
Query: 490 RQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAG 549
+QP ALTRV SVSQPGVRPAC + L++G FSAG +PC TS+ LGSTDTIL+G+N I G
Sbjct: 541 QQPQLALTRVPSVSQPGVRPACPGQPLANGPFSAGHVPCSTSRTLGSTDTILIGNNHITG 600
Query: 550 SESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPL 609
S SNGNVPYLQ+N TLPHN T+L SS EEPW+ QLSNS QGLHK QSS +GPN E+PL
Sbjct: 601 SGSNGNVPYLQRNALTLPHNRTNLTSSAEEPWKNQLSNSTQGLHKGQSSHSAGPNGERPL 660
Query: 610 FSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKP 669
STG +Q+ QA +GI+ N H TLPSNSV QG A +HLS HTATSGGQQGI TKESKP
Sbjct: 661 SSTGPSQHLQAAGSGIQNQNGHPTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKP 720
Query: 670 SKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS--PNLLIADNPQL 727
S N VPETSRHTG+T N A V+GL NHVHQ+ ADAV SP+HGDS P LL +DNPQL
Sbjct: 721 SGNILTVPETSRHTGETPNSTASVEGLPNHVHQMTADAVCSPSHGDSKSPGLLSSDNPQL 780
Query: 728 SALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINS 787
SALL+GKAN NVGTGTCDKVNNIHPAVHTKTD+SVASSPSSAISTATPSPKSTEQ + NS
Sbjct: 781 SALLMGKANNNVGTGTCDKVNNIHPAVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNS 840
Query: 788 VTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKAC 847
VTSLNSPHSGLHT+NGEG+ +SQS K DL L +H+ + QI+PSMSVSI PSS EVLKAC
Sbjct: 841 VTSLNSPHSGLHTINGEGMEESQSPMKTDLLLVNHKPSPQIIPSMSVSIYPSSAEVLKAC 900
Query: 848 RNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 907
RN GKNGLSNS ILLDKCPPPRPP+SPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC
Sbjct: 901 RNLGKNGLSNSSILLDKCPPPRPPSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFC 960
Query: 908 TNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 967
TNP NPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI
Sbjct: 961 TNPNNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKI 1020
Query: 968 WRCESNRSHTTIAKYAQYQASSFQESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFK 1027
W CESNRSHTTIAKYAQYQASSFQESLREENEKR+ HKDHSD+ESTSS+NSGRRRKGPFK
Sbjct: 1021 WHCESNRSHTTIAKYAQYQASSFQESLREENEKRSHHKDHSDSESTSSDNSGRRRKGPFK 1080
Query: 1028 TIKFGTNIDLSDNKKWKLQLHELTKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPG 1087
TIKFGTNIDLSD+KKWKLQLHELTKLPAF RVVSAGNLL+HVGHTILGMNTVQLYMKVPG
Sbjct: 1081 TIKFGTNIDLSDDKKWKLQLHELTKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPG 1140
Query: 1088 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDL 1147
SRTPGHQENNNFCSVNINIGPGDCEWFVVPE YWGVLNDFCEKNNLNFLM SWWPNLEDL
Sbjct: 1141 SRTPGHQENNNFCSVNINIGPGDCEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDL 1200
Query: 1148 YEANVPVYRFIQRPGDLVWINAGTVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNK 1207
YEANVPVYRFIQRPGDLVWINAGTVHWVQA+GWCNNIAWNVGPLTACQYKLAVERYEWNK
Sbjct: 1201 YEANVPVYRFIQRPGDLVWINAGTVHWVQAIGWCNNIAWNVGPLTACQYKLAVERYEWNK 1260
Query: 1208 LKSVKSPVPMVHLSWNMARNIKVSDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWH 1267
L+SVKS VPMVHLSWNMARNIKVSDPKLFEMIKYCLL+ LKQ QTLREAL+AAGKE+IWH
Sbjct: 1261 LQSVKSIVPMVHLSWNMARNIKVSDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWH 1320
Query: 1268 GRTNDEPAHYCSICEVEVFNLLFVTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKM 1327
GRT +EPAHYCSICEVEVF+LLFVTNESN++KTYIVHC DCARKTS +LENFVVLEQYKM
Sbjct: 1321 GRTKEEPAHYCSICEVEVFDLLFVTNESNSRKTYIVHCQDCARKTSGNLENFVVLEQYKM 1380
Query: 1328 EDLIQVYDQFTLALSLSSSS 1347
EDL+QVYDQFTLA L S+S
Sbjct: 1381 EDLMQVYDQFTLAPPLPSAS 1400
>gi|33188429 tetratricopeptide repeat protein isoform 1 [Homo
sapiens]
Length = 1079
Score = 2022 bits (5239), Expect = 0.0
Identities = 995/995 (100%), Positives = 995/995 (100%)
Query: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH
Sbjct: 1 MKSCAVSLTTAAVAFGDEAKKMAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLH 60
Query: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ
Sbjct: 61 EDGARTKTLLGKAVRCYESLILKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQ 120
Query: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY
Sbjct: 121 ADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDY 180
Query: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA
Sbjct: 181 KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKA 240
Query: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA
Sbjct: 241 TVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDA 300
Query: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE
Sbjct: 301 FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYE 360
Query: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL
Sbjct: 361 SCNQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVYSLCL 420
Query: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS
Sbjct: 421 TPQKLQHLEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDS 480
Query: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI
Sbjct: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTI 540
Query: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL
Sbjct: 541 LLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCL 600
Query: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG
Sbjct: 601 SGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQG 660
Query: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL
Sbjct: 661 IMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLL 720
Query: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST
Sbjct: 721 IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKST 780
Query: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS
Sbjct: 781 EQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
Query: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF
Sbjct: 841 TEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFF 900
Query: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD
Sbjct: 901 PPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWD 960
Query: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLR 995
PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLR
Sbjct: 961 PTGTKKIWRCESNRSHTTIAKYAQYQASSFQESLR 995
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 697 bits (1800), Expect = 0.0
Identities = 342/589 (58%), Positives = 427/589 (72%), Gaps = 9/589 (1%)
Query: 752 PAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNS-PHSGLHTVNGEGLGKSQ 810
PA + AS P P P + + + SL+ P L L K +
Sbjct: 1056 PAPSAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGPPKELKI----RLIKVE 1111
Query: 811 SSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRP 870
S K + + +++S C + +V++A RN G L +P
Sbjct: 1112 SGDKETFIASEVEERRLRMADLTISHC--AADVVRASRNAKVKGKFRESYL-SPAQSVKP 1168
Query: 871 PTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGL 930
+ LP++KLNPPTPSIYLE+KRDAF P L QFCT+P+NP+TVIRGLAG+L+L+LGL
Sbjct: 1169 KINTEEKLPREKLNPPTPSIYLESKRDAFSPVLLQFCTDPRNPITVIRGLAGSLRLNLGL 1228
Query: 931 FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSF 990
FSTKTLVEA+ EH VEVRTQ+ QP+DENWD TGT++IW CES+RSHTTIAKYAQYQASSF
Sbjct: 1229 FSTKTLVEASGEHTVEVRTQVQQPSDENWDLTGTRQIWPCESSRSHTTIAKYAQYQASSF 1288
Query: 991 QESLREENEKRTQHKDHSDNESTSSENSGRRRKGPFKTIKFGTNIDLSDNKKWKLQLHEL 1050
QESL+EE E + + D+ + + +S K IKFGTNIDLSD K+WK QL EL
Sbjct: 1289 QESLQEEKESEDEESEEPDSTTGTPPSSAPDPKN-HHIIKFGTNIDLSDAKRWKPQLQEL 1347
Query: 1051 TKLPAFARVVSAGNLLTHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1110
KLPAF RV S GN+L+HVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD
Sbjct: 1348 LKLPAFMRVTSTGNMLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD 1407
Query: 1111 CEWFVVPEDYWGVLNDFCEKNNLNFLMSSWWPNLEDLYEANVPVYRFIQRPGDLVWINAG 1170
CEWF V E YW ++ FC+++ +++L SWWP L+DLY +N+PVYRF+QRPGDLVWINAG
Sbjct: 1408 CEWFAVHEHYWETISAFCDRHGVDYLTGSWWPILDDLYASNIPVYRFVQRPGDLVWINAG 1467
Query: 1171 TVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLKSVKSPVPMVHLSWNMARNIKV 1230
TVHWVQA GWCNNIAWNVGPLTA QY+LA+ERYEWN++K+VKS VPM+H+SWN+AR +K+
Sbjct: 1468 TVHWVQATGWCNNIAWNVGPLTAYQYQLALERYEWNEVKNVKSIVPMIHVSWNVARTVKI 1527
Query: 1231 SDPKLFEMIKYCLLKILKQYQTLREALVAAGKEVIWHGRTNDEPAHYCSICEVEVFNLLF 1290
SDP LF+MIK+CLL+ +K Q RE+LV AGK++ + GR DEPA+YC+ C+VEVFN+LF
Sbjct: 1528 SDPDLFKMIKFCLLQSMKHCQVQRESLVRAGKKIAYQGRVKDEPAYYCNECDVEVFNILF 1587
Query: 1291 VTNESNTQKTYIVHCHDCARKTSKSLENFVVLEQYKMEDLIQVYDQFTL 1339
VT+E+ ++ TY+VHC CAR+ S L+ VVLEQY+ E+L Q YD FTL
Sbjct: 1588 VTSENGSRNTYLVHCEGCARRRSAGLQGVVVLEQYRTEELAQAYDAFTL 1636
Score = 46.2 bits (108), Expect = 2e-04
Identities = 49/196 (25%), Positives = 80/196 (40%), Gaps = 22/196 (11%)
Query: 249 MHHNMDLVGDKATKESYAIQYLQ-----KSLEADPNSGQSWYFLGRCYSSIGKVQ-DAFI 302
MH +D G +A +E++A+ L S P +W GRC +SIG+ A +
Sbjct: 1 MHRAVDPPGARAAREAFALGGLSCAGAWSSCPPHPPPRSAWLPGGRCSASIGQPPLPAPL 60
Query: 303 SYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESC 362
S + + + +++L + A+ + W LG LYES
Sbjct: 61 PPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPAQPGLWEQLGQLYESE 120
Query: 363 NQPQDAIKCYLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHH------PVQQVY 416
+ ++A +CY +A R + + L RI LQ + WN H P++QV+
Sbjct: 121 HDSEEATRCYHSALRYG--GSFAELGPRIGRLQQ-AQLWNFHTGSCQHRAKVLPPLEQVW 177
Query: 417 SLCLTPQKLQHLEQLR 432
+L HLE R
Sbjct: 178 NLL-------HLEHKR 186
Score = 30.8 bits (68), Expect = 9.2
Identities = 16/40 (40%), Positives = 20/40 (50%), Gaps = 4/40 (10%)
Query: 866 PPPRPPTSPYPPLPKDKLNPP----TPSIYLENKRDAFFP 901
PPP PP P PPLP +PP P ++ DA+ P
Sbjct: 253 PPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGP 292
>gi|32307150 O-linked GlcNAc transferase isoform 2 [Homo sapiens]
Length = 1036
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/336 (21%), Positives = 137/336 (40%), Gaps = 47/336 (13%)
Query: 73 AVRCYESLILKAEGKVESDFFC---QLGHFNLLLEDYSKALSAYQRYYSLQADY---WKN 126
AV+ Y S + + D +C LG+ L +A + Y + Q ++ W N
Sbjct: 132 AVQAYVSAL-----QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSN 186
Query: 127 AAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKH 186
LG V+ AI F+ + +DP+F A ++ LG + K + ++
Sbjct: 187 ------LGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YINLGNVLKEARIFDRAVAA 237
Query: 187 FQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--------NLPAQV 238
+ AL + ++A + ++A +Y Q A + Y + ++ + NL +
Sbjct: 238 YLRAL----SLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 293
Query: 239 KA-----------TVLQQLGWMH----HNMDLVGDKATKESYAIQYLQKSLEADPNSGQS 283
K +L H +N+ + + A++ +K+LE P +
Sbjct: 294 KEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 353
Query: 284 WYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQ 343
L GK+Q+A + Y+++I S AD + ++G ++ ALQ Y A+Q
Sbjct: 354 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 413
Query: 344 LDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSK 379
++ A A +L ++++ +AI Y A + K
Sbjct: 414 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 449
Score = 44.7 bits (104), Expect = 6e-04
Identities = 25/107 (23%), Positives = 51/107 (47%)
Query: 273 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 332
+++ +P +++ LG Y G++Q+A YR ++ D + ++
Sbjct: 71 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 130
Query: 333 DALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSK 379
A+QAY+ A+Q + DLG L ++ + ++A CYL A ++
Sbjct: 131 GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 177
Score = 40.4 bits (93), Expect = 0.012
Identities = 55/258 (21%), Positives = 101/258 (39%), Gaps = 41/258 (15%)
Query: 91 DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYG-LGLVYFYYNAFHWAIKA 149
D + LG+ + +A++AY R SL N A ++G L VY+ AI
Sbjct: 216 DAYINLGNVLKEARIFDRAVAAYLRALSLSP----NHAVVHGNLACVYYEQGLIDLAIDT 271
Query: 150 FQDVLYVDPSF----CRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSN-AEI 204
++ + + P F C G + + Y ++L+ L + +L+N A I
Sbjct: 272 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALR-----LCPTHADSLNNLANI 326
Query: 205 QFHIAHLYETQRKYHSAKEAYEQLLQTE-NLPAQVKATVLQQLG-----WMHHNMDLVGD 258
+ ++ E R Y A E + + NL A+VLQQ G MH+ +
Sbjct: 327 KREQGNIEEAVRLYRKALEVFPEFAAAHSNL-----ASVLQQQGKLQEALMHYKEAIRIS 381
Query: 259 KATKESY---------------AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFIS 303
++Y A+Q ++++ +P + L + G + +A S
Sbjct: 382 PTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAS 441
Query: 304 YRQSIDKSEASADTWCSI 321
YR ++ D +C++
Sbjct: 442 YRTALKLKPDFPDAYCNL 459
>gi|32307148 O-linked GlcNAc transferase isoform 1 [Homo sapiens]
Length = 1046
Score = 55.5 bits (132), Expect = 3e-07
Identities = 71/336 (21%), Positives = 137/336 (40%), Gaps = 47/336 (13%)
Query: 73 AVRCYESLILKAEGKVESDFFC---QLGHFNLLLEDYSKALSAYQRYYSLQADY---WKN 126
AV+ Y S + + D +C LG+ L +A + Y + Q ++ W N
Sbjct: 142 AVQAYVSAL-----QYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSN 196
Query: 127 AAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKH 186
LG V+ AI F+ + +DP+F A ++ LG + K + ++
Sbjct: 197 ------LGCVFNAQGEIWLAIHHFEKAVTLDPNFLDA---YINLGNVLKEARIFDRAVAA 247
Query: 187 FQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTE--------NLPAQV 238
+ AL + ++A + ++A +Y Q A + Y + ++ + NL +
Sbjct: 248 YLRAL----SLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANAL 303
Query: 239 KA-----------TVLQQLGWMH----HNMDLVGDKATKESYAIQYLQKSLEADPNSGQS 283
K +L H +N+ + + A++ +K+LE P +
Sbjct: 304 KEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAA 363
Query: 284 WYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQ 343
L GK+Q+A + Y+++I S AD + ++G ++ ALQ Y A+Q
Sbjct: 364 HSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQ 423
Query: 344 LDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSK 379
++ A A +L ++++ +AI Y A + K
Sbjct: 424 INPAFADAHSNLASIHKDSGNIPEAIASYRTALKLK 459
Score = 44.7 bits (104), Expect = 6e-04
Identities = 25/107 (23%), Positives = 51/107 (47%)
Query: 273 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 332
+++ +P +++ LG Y G++Q+A YR ++ D + ++
Sbjct: 81 AIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDME 140
Query: 333 DALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSK 379
A+QAY+ A+Q + DLG L ++ + ++A CYL A ++
Sbjct: 141 GAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQ 187
Score = 40.4 bits (93), Expect = 0.012
Identities = 55/258 (21%), Positives = 101/258 (39%), Gaps = 41/258 (15%)
Query: 91 DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYG-LGLVYFYYNAFHWAIKA 149
D + LG+ + +A++AY R SL N A ++G L VY+ AI
Sbjct: 226 DAYINLGNVLKEARIFDRAVAAYLRALSLSP----NHAVVHGNLACVYYEQGLIDLAIDT 281
Query: 150 FQDVLYVDPSF----CRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSN-AEI 204
++ + + P F C G + + Y ++L+ L + +L+N A I
Sbjct: 282 YRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALR-----LCPTHADSLNNLANI 336
Query: 205 QFHIAHLYETQRKYHSAKEAYEQLLQTE-NLPAQVKATVLQQLG-----WMHHNMDLVGD 258
+ ++ E R Y A E + + NL A+VLQQ G MH+ +
Sbjct: 337 KREQGNIEEAVRLYRKALEVFPEFAAAHSNL-----ASVLQQQGKLQEALMHYKEAIRIS 391
Query: 259 KATKESY---------------AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFIS 303
++Y A+Q ++++ +P + L + G + +A S
Sbjct: 392 PTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAS 451
Query: 304 YRQSIDKSEASADTWCSI 321
YR ++ D +C++
Sbjct: 452 YRTALKLKPDFPDAYCNL 469
>gi|118402596 cell division cycle protein 23 [Homo sapiens]
Length = 597
Score = 54.3 bits (129), Expect = 8e-07
Identities = 32/110 (29%), Positives = 49/110 (44%)
Query: 266 AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLY 325
A Y Q++L+ +P +W +G Y + A +YR +I+ ++ W +G Y
Sbjct: 350 AALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQTY 409
Query: 326 QQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 375
+ P L Y A QL + + LG YE NQ +A KCY A
Sbjct: 410 EILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKKCYWRA 459
Score = 48.5 bits (114), Expect = 4e-05
Identities = 58/285 (20%), Positives = 117/285 (41%), Gaps = 26/285 (9%)
Query: 91 DFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAF 150
+FF L H L+ +AL YQ + + K++ + + + Y A+ F
Sbjct: 231 EFF--LAHIYTELQLIEEALQKYQNL--IDVGFSKSSYIVSQIAVAYHNIRDIDKALSIF 286
Query: 151 QDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFH--I 208
++ DP R + + L+ Y S+K +L+ + N C + ++ I
Sbjct: 287 NELRKQDPY--RIENMDTFSNLL------YVRSMKS-ELSYLAHNLCEIDKYRVETCCVI 337
Query: 209 AHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQ 268
+ Y + ++ A +++ L+ P + A L H M++ A AIQ
Sbjct: 338 GNYYSLRSQHEKAALYFQRALKLN--PRYLGAWTLMG----HEYMEMKNTSA-----AIQ 386
Query: 269 YLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQ 328
+ ++E + ++WY LG+ Y + YR++ + ++G Y++
Sbjct: 387 AYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKL 446
Query: 329 NQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYL 373
NQ ++A + Y A + A + L L+E + + A +CY+
Sbjct: 447 NQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYI 491
Score = 43.5 bits (101), Expect = 0.001
Identities = 38/198 (19%), Positives = 79/198 (39%), Gaps = 30/198 (15%)
Query: 205 QFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHN-------MDLVG 257
+F +AH+Y + A + Y+ L+ ++ + ++ Q+ +HN + +
Sbjct: 231 EFFLAHIYTELQLIEEALQKYQNLI---DVGFSKSSYIVSQIAVAYHNIRDIDKALSIFN 287
Query: 258 DKATKESYAIQ-------------------YLQKSL-EADPNSGQSWYFLGRCYSSIGKV 297
+ ++ Y I+ YL +L E D ++ +G YS +
Sbjct: 288 ELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQH 347
Query: 298 QDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGT 357
+ A + +++++ + W +G Y + A+QAY A++++ AW LG
Sbjct: 348 EKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEVNKRDYRAWYGLGQ 407
Query: 358 LYESCNQPQDAIKCYLNA 375
YE P + Y A
Sbjct: 408 TYEILKMPFYCLYYYRRA 425
Score = 35.4 bits (80), Expect = 0.37
Identities = 38/211 (18%), Positives = 79/211 (37%), Gaps = 24/211 (11%)
Query: 170 LGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLL 229
+G + + + ++ + +FQ AL NP L + + H Y + +A +AY +
Sbjct: 337 IGNYYSLRSQHEKAALYFQRAL-KLNPRYLGAWTL---MGHEYMEMKNTSAAIQAYRHAI 392
Query: 230 QTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGR 289
+ + W + + + Y + Y +++ + PN + LG
Sbjct: 393 EVNKRDYRA---------W--YGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441
Query: 290 CYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYI--------CA 341
CY + ++ +A Y ++ + + L++Q + A Q YI C
Sbjct: 442 CYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCG 501
Query: 342 VQLDH-GHAAAWMDLGTLYESCNQPQDAIKC 371
++H + A+ L Y C +A C
Sbjct: 502 EIVEHLEESTAFRYLAQYYFKCKLWDEASTC 532
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 52.4 bits (124), Expect = 3e-06
Identities = 88/458 (19%), Positives = 156/458 (34%), Gaps = 22/458 (4%)
Query: 372 YLNAARSKRCSNTSTLAARIKFLQNGSDNWNGGQSLSHHPVQQVY----SLCLTPQKLQH 427
+L AA + ++TS S N G S++ V S+ +
Sbjct: 17 HLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVT 76
Query: 428 LEQLRANRDNLNPAQKHQLEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDSS---LPT 484
+ ++ A + + S + + +T ++ + T SS T
Sbjct: 77 NSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTAT 136
Query: 485 NSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGSTDTILLGS 544
NS S+ GA T +S S A S S+G S+ + +
Sbjct: 137 NSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTAT 196
Query: 545 NCIAGSESNGNVPYLQQNTHTLPHNH---TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLS 601
N + + S+G + T + T+ SST +NS S + +
Sbjct: 197 NSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAG--T 254
Query: 602 GPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGI 661
N E S+G+ + S+ + +T +S P A++ + ++T+
Sbjct: 255 ATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANT 314
Query: 662 MFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLI 721
+S + + + S + +S S+ + A +S + S
Sbjct: 315 ATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTST 374
Query: 722 ADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTE 781
A N + S + G T T + + T T +S +S+ SS STAT S ST
Sbjct: 375 ATNSESSTVSSG-----ASTATTSESSTTSSGASTAT-NSESSTVSSGASTATNSESSTT 428
Query: 782 QRSINSVT----SLNSPHSGLHTVNGEGLGKSQSSTKV 815
N+ T S+ S SG + G +ST V
Sbjct: 429 SSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAV 466
Score = 44.7 bits (104), Expect = 6e-04
Identities = 67/341 (19%), Positives = 121/341 (35%), Gaps = 23/341 (6%)
Query: 515 LLSSGAFSAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLN 574
++SSGA +A G+S T + + + SNG HT + ++
Sbjct: 37 VISSGASTA--TNSGSSVTSSGVSTATISGSSVT---SNGVSIVTNSEFHT---TSSGIS 88
Query: 575 SSTEEPWRKQLSNSAQGLHKSQSSCLSGP----NEEQPLFSTGSAQYHQATSTGIKKANE 630
++T + S + + S+ SG N E S+G++ + S+
Sbjct: 89 TATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGAS 148
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
T +S +A + + ++T+ ES +R+ S + +S
Sbjct: 149 TATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGAS 208
Query: 691 ADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKA----------NGNVG 740
S A +S + S A N + S G + G
Sbjct: 209 TATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAG 268
Query: 741 TGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHT 800
T T + + + + T T+ S +S+PSS +TAT S ST N+ T+ +S +
Sbjct: 269 TATNSESSTVSSGISTVTN-SESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGA 327
Query: 801 VNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSST 841
S +S+ S ST+ S + + S+T
Sbjct: 328 STATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT 368
Score = 43.9 bits (102), Expect = 0.001
Identities = 91/410 (22%), Positives = 148/410 (36%), Gaps = 37/410 (9%)
Query: 465 AQVRTTGIHNGAITDSSLPTNSVS---NRQPHGALTRVSSVSQPGVRPACVEKLLSSGAF 521
+ V ++G+ I+ SS+ +N VS N + H + +S+ + +SSG
Sbjct: 50 SSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEF------STVSSGIS 103
Query: 522 SAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPW 581
A T+ ST T S +G+ + N T + T+ +SST
Sbjct: 104 IATNSESSTTSSGASTATNSESSTPSSGASTATNSD--SSTTSSGASTATNSDSSTTSSE 161
Query: 582 RKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQ 641
+NS S +S + +E + S S + +ST A+ S +
Sbjct: 162 ASTATNSESSTTSSGASTATN-SESSTVSSRASTATNSESSTTSSGASTATNSESRTTSN 220
Query: 642 GDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVH 701
G + S + TS G ++ S PS + T + G A S+ V
Sbjct: 221 GAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTA-TNSESSTVS 279
Query: 702 QLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHS 761
I+ +S + S A N + S G N T + T + S
Sbjct: 280 SGISTVTNSESSTPSSGANTATNSESSTTSSG---ANTATNSDSST--------TSSGAS 328
Query: 762 VASSP-----SSAISTATPSPKSTEQRSINSVTSLNS--PHSGLHTVNGE-----GLGKS 809
A++ SS STAT S ST ++ T+ S SG T G S
Sbjct: 329 TATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAS 388
Query: 810 QSSTKVDLPLASHRSTSQILPSMSVSI-CPSSTEVLKACRNPGKNGLSNS 858
++T +S ST+ S +VS ++T + + G N +NS
Sbjct: 389 TATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTATNS 438
>gi|224809432 transmembrane and tetratricopeptide repeat containing
3 [Homo sapiens]
Length = 914
Score = 51.2 bits (121), Expect = 7e-06
Identities = 49/215 (22%), Positives = 94/215 (43%), Gaps = 26/215 (12%)
Query: 174 FKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTEN 233
F N D++S F AL +NA++ ++ H E ++ + A + + Q +
Sbjct: 422 FHRNWDWESEYTLFMSAL----KVNKNNAKLWNNVGHALENEKNFERALKYFLQATHVQ- 476
Query: 234 LPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEAD------------PNSG 281
P + A + +G + N++ TKE+ + KSL PN
Sbjct: 477 -PDDIGAHM--NVGRTYKNLN-----RTKEAEESYMMAKSLMPQIIPGKKYAARIAPNHL 528
Query: 282 QSWYFLGRCY-SSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYIC 340
+ L ++ ++++A YRQ+I + S G L + N+P+ A +AY+
Sbjct: 529 NVYINLANLIRANESRLEEADQLYRQAISMRPDFKQAYISRGELLLKMNKPLKAKEAYLK 588
Query: 341 AVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 375
A++LD +A W +L ++ +P +A+K + A
Sbjct: 589 ALELDRNNADLWYNLAIVHIELKEPNEALKNFNRA 623
>gi|7661950 SH2 domain binding protein 1 [Homo sapiens]
Length = 1173
Score = 50.8 bits (120), Expect = 9e-06
Identities = 61/269 (22%), Positives = 116/269 (43%), Gaps = 26/269 (9%)
Query: 104 EDYSKALSAYQRYYSLQADYWKNAAFL---YGLGLVYFYYNAFHWAIKAFQDVLYVDPSF 160
EDY +A +Q YY QA + +++F+ +GLG +Y Y A + F+ VL P+
Sbjct: 320 EDYDQA---FQYYY--QATQFASSSFVLPFFGLGQMYIYRGDKENASQCFEKVLKAYPNN 374
Query: 161 CRAKEIHLRLGLMFKVNTDY--KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKY 218
+I LG ++ + D + K + + P + E +A + E Q
Sbjct: 375 YETMKI---LGSLYAASEDQEKRDIAKGHLKKVTEQYP---DDVEAWIELAQILE-QTDI 427
Query: 219 HSAKEAY---EQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLE 275
A AY ++LQ E + A V +L +G +H + +G+ ++ + E
Sbjct: 428 QGALSAYGTATRILQ-EKVQADVPPEILNNVGALHFRLGNLGEAKKYFLASLDRAKAEAE 486
Query: 276 ADPN-----SGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQ 330
D + S + Y L R Y ++ + +A Y+ + + D + +G + + +
Sbjct: 487 HDEHYYNAISVTTSYNLARLYEAMCEFHEAEKLYKNILREHPNYVDCYLRLGAMARDKGN 546
Query: 331 PMDALQAYICAVQLDHGHAAAWMDLGTLY 359
+A + A+Q++ H AW +G L+
Sbjct: 547 FYEASDWFKEALQINQDHPDAWSLIGNLH 575
Score = 40.4 bits (93), Expect = 0.012
Identities = 38/211 (18%), Positives = 94/211 (44%), Gaps = 10/211 (4%)
Query: 131 YGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLA 190
Y L +Y FH A K ++++L P++ + +LRLG M + ++ + F+ A
Sbjct: 501 YNLARLYEAMCEFHEAEKLYKNILREHPNYV---DCYLRLGAMARDKGNFYEASDWFKEA 557
Query: 191 LIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMH 250
L + + I +L+ ++++ ++ +E++L+ + + + + W+
Sbjct: 558 L----QINQDHPDAWSLIGNLHLAKQEWGPGQKKFERILKQPSTQSDTYSMLALGNVWLQ 613
Query: 251 HNMDLVGDKATKESY---AIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQS 307
D+ ++ + A+ ++ L D + + +G + G ++A + Q
Sbjct: 614 TLHQPTRDREKEKRHQDRALAIYKQVLRNDAKNLYAANGIGAVLAHKGYFREARDVFAQV 673
Query: 308 IDKSEASADTWCSIGVLYQQQNQPMDALQAY 338
+ + +D W ++ +Y +Q Q + A+Q Y
Sbjct: 674 REATADISDVWLNLAHIYVEQKQYISAVQMY 704
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 50.1 bits (118), Expect = 1e-05
Identities = 75/325 (23%), Positives = 118/325 (36%), Gaps = 33/325 (10%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P +T S ++T++ + +
Sbjct: 951 TALPGSTTTPGLSERSTTFHSSPRSPATTLS------PASTTSSGVSEESTTSRSRPGST 1004
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
H T + P LS H+ TS G T P+ + P T +S+G
Sbjct: 1005 HTT----AFPDSTTTPGLSRHSTTSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSSGS 1059
Query: 691 ADVKGLSNHVHQLIADAVSSPNH---GDSPNLLIADNPQLSALLIGKANGNVGTG----T 743
D L S+ H G + L D+ S ++ + TG T
Sbjct: 1060 TDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 1119
Query: 744 CDKVNNIHPAV---------HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++ P + H + H+ S PS+A TA +T RS S + + P
Sbjct: 1120 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA--TAPVEESTTYHRSPGSTPTTHFP 1177
Query: 795 HSGLHTVNGEGLGKSQSSTKVD--LPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGK 852
S + + E SS P ++H +TS S + I P STE+ +
Sbjct: 1178 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 1237
Query: 853 NGLSNSCILLDKCPPPRPPTSPYPP 877
GLS + PR PT+ P
Sbjct: 1238 PGLSEASTTF--YSSPRSPTTTLSP 1260
Score = 48.9 bits (115), Expect = 3e-05
Identities = 75/325 (23%), Positives = 117/325 (36%), Gaps = 33/325 (10%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P +T S ++T++ + +
Sbjct: 2034 TALPGSTTTPGLSEKSTTFHSSPRSPATTLS------PASTTSSGVSEESTTSHSRPGST 2087
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
H T + P LS H+ TS G T P+ + P T +S G
Sbjct: 2088 HTT----AFPDSTTTPGLSRHSTTSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSPGS 2142
Query: 691 ADVKGLSNHVHQLIADAVSSPNH---GDSPNLLIADNPQLSALLIGKANGNVGTG----T 743
D L S+ H G + L D+ S ++ + TG T
Sbjct: 2143 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2202
Query: 744 CDKVNNIHPAV---------HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++ P + H + H+ S PS+A TA +T RS S + + P
Sbjct: 2203 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA--TAPVEESTTYHRSPGSTPTTHFP 2260
Query: 795 HSGLHTVNGEGLGKSQSSTKVD--LPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGK 852
S + + E SS P ++H +TS S + I P STE+ +
Sbjct: 2261 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 2320
Query: 853 NGLSNSCILLDKCPPPRPPTSPYPP 877
GLS + PR PT+ P
Sbjct: 2321 PGLSEASTTF--YSSPRSPTTTLSP 2343
Score = 47.8 bits (112), Expect = 7e-05
Identities = 76/325 (23%), Positives = 118/325 (36%), Gaps = 33/325 (10%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P +T S ++T++ + +
Sbjct: 3591 TALPGSTTTPGLSEKSTTFHSSPRSPATTLS------PASTTSSGVSEESTTSHSRPGST 3644
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
H T + P LS H+ TS G T S S + S T +S+G
Sbjct: 3645 HTT----AFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQEST-TSHSSSGS 3699
Query: 691 ADVKGLSNHVHQLIADAVSSPNH---GDSPNLLIADNPQLSALLIGKANGNVGTG----T 743
D L S+ H G + L D+ S ++ + TG T
Sbjct: 3700 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 3759
Query: 744 CDKVNNIHPAV---------HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++ P + H + H+ S PS+A TA +T RS S + + P
Sbjct: 3760 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA--TAPVEESTTYHRSPGSTPTTHFP 3817
Query: 795 HSGLHTVNGEGLGKSQSSTKVD--LPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGK 852
S + + E SS P ++H +TS S + I P STE+ +
Sbjct: 3818 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 3877
Query: 853 NGLSNSCILLDKCPPPRPPTSPYPP 877
GLS + PR PT+ P
Sbjct: 3878 PGLSEASTTF--YSSPRSPTTTLSP 3900
Score = 46.2 bits (108), Expect = 2e-04
Identities = 68/309 (22%), Positives = 108/309 (34%), Gaps = 12/309 (3%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + A S + THT+ + ++ EEP S S H
Sbjct: 1920 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTH 1979
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTA 653
SS SG +EE ST S AT T + A ++ S TA
Sbjct: 1980 FPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 2035
Query: 654 TSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNH 713
G +++S + P T+ T++ + ++H + P+
Sbjct: 2036 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 2095
Query: 714 GDSPNLLIADNPQLSALLIGKANGNVGTGTCD-KVNNIHPAVHTKTDHSVASSPSSAIST 772
+P L S+ G+ T P+ + T HS S +A+S
Sbjct: 2096 TTTPGLSRHSTTSHSS------PGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSP 2149
Query: 773 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM 832
+ + S Q S +S S H+ L + G ++ST+V S R+T S
Sbjct: 2150 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 2209
Query: 833 SVSICPSST 841
S + ST
Sbjct: 2210 SPGLQGEST 2218
Score = 43.1 bits (100), Expect = 0.002
Identities = 73/325 (22%), Positives = 115/325 (35%), Gaps = 33/325 (10%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L S P + S + +S + LS P +T S +++++ + +
Sbjct: 2508 TTLPGSPTTPSLSEKSTTFYTSPRSPDATLS------PATTTSSGVSEESSTSHSQPGST 2561
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
H T + P LS H+ TS G T P+ + P T +S G
Sbjct: 2562 HTT----AFPDSTTTPGLSRHSTTSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSPGS 2616
Query: 691 ADVKGLSNHVHQLIADAVSSPNH---GDSPNLLIADNPQLSALLIGKANGNVGTG----T 743
D L S+ H G + L D+ S ++ + TG T
Sbjct: 2617 TDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2676
Query: 744 CDKVNNIHPAV---------HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++ P + H + H+ S PS+A TA +T RS S + + P
Sbjct: 2677 LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTA--TAPVEESTTYHRSPGSTPTTHFP 2734
Query: 795 HSGLHTVNGEGLGKSQSSTKVD--LPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGK 852
S + + E SS P ++H +TS S + I P STE+ +
Sbjct: 2735 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 2794
Query: 853 NGLSNSCILLDKCPPPRPPTSPYPP 877
GLS + PR PT+ P
Sbjct: 2795 PGLSEASTTF--YSSPRSPTTTLSP 2817
Score = 41.6 bits (96), Expect = 0.005
Identities = 63/273 (23%), Positives = 92/273 (33%), Gaps = 34/273 (12%)
Query: 595 SQSSCLSGPNEEQPLFSTGSAQYHQ---ATSTGIKKANEHLTLPSNSVPQGDADSHLSCH 651
++ S SG EE F A AT T E T PS+S G + LS
Sbjct: 2428 TEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSS---GSTGTTLSPA 2484
Query: 652 TATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSP 711
+T+ G G ES PS+ ET+ G + K + + DA SP
Sbjct: 2485 RSTTSGLVG-----ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 2539
Query: 712 -----------------NHGDSPNLLIADNPQLSALLIGKANGNVGTGTCD------KVN 748
G + D+ L + G+ D
Sbjct: 2540 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT 2599
Query: 749 NIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGK 808
P+ + T HS S +A+S + + S Q S +S S H+ L + G
Sbjct: 2600 TSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGI 2659
Query: 809 SQSSTKVDLPLASHRSTSQILPSMSVSICPSST 841
++ST+V S R+T S S + ST
Sbjct: 2660 VEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 2692
Score = 41.2 bits (95), Expect = 0.007
Identities = 65/309 (21%), Positives = 106/309 (34%), Gaps = 12/309 (3%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + + THT+ + ++ EEP S S H
Sbjct: 3477 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 3536
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTA 653
SS SG +EE ST S AT T + A ++ S TA
Sbjct: 3537 FPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 3592
Query: 654 TSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNH 713
G +++S + P T+ T++ + ++H + P+
Sbjct: 3593 LPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDS 3652
Query: 714 GDSPNLLIADNPQLSALLIGKANGNVGTGTCD-KVNNIHPAVHTKTDHSVASSPSSAIST 772
+P L S+ G+ T + + T HS + S +A+S
Sbjct: 3653 TTTPGLSRHSTTSHSS------PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSP 3706
Query: 773 ATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSM 832
+ + S Q S +S S H+ L + G ++ST+V S R+T S
Sbjct: 3707 GSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASST 3766
Query: 833 SVSICPSST 841
S + ST
Sbjct: 3767 SPGLQGEST 3775
Score = 40.8 bits (94), Expect = 0.009
Identities = 66/319 (20%), Positives = 109/319 (34%), Gaps = 32/319 (10%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + + THT+ + ++ EEP S S H
Sbjct: 837 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 896
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTL-----PSNSVPQGDADSHL 648
SS SG +EE ST S AT T + A ++ ++ + G ++
Sbjct: 897 FPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 952
Query: 649 SCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAV 708
+ T+ G T S P + + S TS+G ++
Sbjct: 953 LPGSTTTPGLSERSTTFHSSPRSPATTLSPAST----TSSGVSE------------ESTT 996
Query: 709 SSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCD------KVNNIHPAVHTKTDHSV 762
S G + D+ L + G+ D P+ + T HS
Sbjct: 997 SRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 1056
Query: 763 ASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASH 822
+ S +A+S + + S Q S ++ S H+ L + G ++ST+V S
Sbjct: 1057 SGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 1116
Query: 823 RSTSQILPSMSVSICPSST 841
R+T S S + ST
Sbjct: 1117 RTTLSPASSTSPGLQGEST 1135
Score = 40.0 bits (92), Expect = 0.015
Identities = 66/302 (21%), Positives = 102/302 (33%), Gaps = 36/302 (11%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + A S + THT+ + ++ EEP S S H
Sbjct: 4753 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTH 4812
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNS-------VPQGDADS 646
+SS SG +EE +A + + GI H T + G ++
Sbjct: 4813 FPESSTTSGRSEES------TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 4866
Query: 647 HLSCHTATSG--GQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLI 704
L+ T G + I+++ P + S TS +S L
Sbjct: 4867 TLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTS-------------SSISGEPTSLY 4913
Query: 705 ADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVAS 764
+ A S+ + + Q S K T + + A T HS
Sbjct: 4914 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHS--- 4970
Query: 765 SPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTV----NGEGLGKSQSSTKVDLPLA 820
P SA+ST +P+ + S S T +SP S T N + QS+ D P
Sbjct: 4971 QPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGF 5030
Query: 821 SH 822
+H
Sbjct: 5031 TH 5032
Score = 39.3 bits (90), Expect = 0.026
Identities = 89/423 (21%), Positives = 162/423 (38%), Gaps = 82/423 (19%)
Query: 465 AQVRTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVR---------PACVEKL 515
A ++G+ + T S P + + P SS + PGV P +
Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFP-------SSTTMPGVSQESTASHSSPGSTDTT 4400
Query: 516 LSSGAFSAGCI-PCGTS--KILGSTDTILLGSNCIAGSESNGNVPYLQQ----NTHTLPH 568
LS G+ +A + P T+ GST+T LL N A + P +T P
Sbjct: 4401 LSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA 4460
Query: 569 NHTDLN--SSTEEPWRK----------------QLSNSAQG-------LHKSQSSCLSGP 603
T S+T + W +LS ++ G H S SS G
Sbjct: 4461 GSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 4520
Query: 604 NEEQ------PLFSTGSAQYHQATSTGIKK----------ANEHLTLPSNSVPQGDADSH 647
+EE P+ + + ++T++G+ + + + + P ++ G +
Sbjct: 4521 SEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEES 4580
Query: 648 LSCHTATSGGQQGIMFTKESKPSKNRSLVPE-TSRHTGDTSNGCADVKGLSNHVHQLIAD 706
+ H++T+ T S PS +LV E TS H+ S S+ +
Sbjct: 4581 TTSHSSTT-------HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD-SSTTSGRSEE 4632
Query: 707 AVSSPNHGDSPNLLIADNPQLSALLIGKANGN-VGTGTCDKV----NNIHPAVHTKTDHS 761
+ +S + D+ ++ +++L+G++ + + +G+ + + P + K+ +
Sbjct: 4633 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKST-T 4691
Query: 762 VASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLAS 821
SSPSS +T + +T RS S T +SP + T +S +S V+ A
Sbjct: 4692 FHSSPSSTPTTHFSASSTTLGRSEESTTVHSSP---VATATTPSPARSTTSGLVEESTAY 4748
Query: 822 HRS 824
H S
Sbjct: 4749 HSS 4751
Score = 38.1 bits (87), Expect = 0.057
Identities = 100/468 (21%), Positives = 172/468 (36%), Gaps = 108/468 (23%)
Query: 465 AQVRTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVR----PACVEKLLSSGA 520
A ++G+ + T S P ++ + P T + VSQ P + LS G+
Sbjct: 3265 ASTTSSGVSEESTTSHSRPGSTHTTAFPGS--TTMPGVSQESTASHSSPGSTDTTLSPGS 3322
Query: 521 FSAGCIPCGTSKIL---GSTDTILLGSNCIAGSESNGNVPYLQQ----NTHTLPHNHTDL 573
+A + ++ GST+T LL N A + P +T P T
Sbjct: 3323 TTASSLGPESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 3382
Query: 574 N--SSTEEPWRK----------------QLSNSAQG-------LHKSQSSCLSGPNEEQ- 607
S+T + W +LS ++ G H S SS G +EE
Sbjct: 3383 QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST 3442
Query: 608 -----PLFSTGSAQYHQATSTGIKK----------ANEHLTLPSNSVPQGDADSHLSCHT 652
P+ + + ++T++G+ + + + + P + G + + H+
Sbjct: 3443 TVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 3502
Query: 653 ATSGGQQGIMFTKESKPSKNRSLVPE-TSRHTGDTSNGCADVKGLSNHVHQLIADAVSSP 711
+T+ T S PS +LV E TS H+ S S+ ++ +S
Sbjct: 3503 STT-------HTISSAPSTTSALVEEPTSYHSSPGSTATTHFPD-SSTTSGRSEESTASH 3554
Query: 712 NHGDSPNLLIADNPQLSALLIGKA------NGNVGT----------GTCDKVNNIHPAVH 755
+ D+ ++ +++L+G++ +G++ T G +K H +
Sbjct: 3555 SSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPR 3614
Query: 756 TK-TDHSVASSPSSAIS---------------TATPSPKSTEQRSINSVTSLNSPHS--- 796
+ T S AS+ SS +S TA P +T S +S TS +SP S
Sbjct: 3615 SPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDT 3674
Query: 797 GLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVL 844
L + G SQ ST SH S+ S ++ P ST L
Sbjct: 3675 TLLPASTTTSGSSQEST------TSHSSSG----STDTALSPGSTTAL 3712
Score = 37.0 bits (84), Expect = 0.13
Identities = 99/461 (21%), Positives = 154/461 (33%), Gaps = 65/461 (14%)
Query: 446 LEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQP 505
L + + F + + ++ RTT + +++ S T S S P + S + P
Sbjct: 276 LSEKSTTFYSSPRSPDRTLSPARTT---SSGVSEKS--TTSHSRPGPTHTIAFPDSTTMP 330
Query: 506 GVRPACVEKLLSSGAFSAGCIPCGTSKIL--GSTDTILLGSNCIAGSESNG--NVPYLQQ 561
GV S + ++ IP T L G+T LG S G L
Sbjct: 331 GV---------SQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 381
Query: 562 NTHT--LPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSG----------PNEEQPL 609
NT T L T ++SST P LS S+ H+ + + P+
Sbjct: 382 NTTTSGLLEASTPVHSSTGSP-HTTLSPSSSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 440
Query: 610 FSTGSAQYHQ-----------ATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQ 658
F S YH A+ST + + E + P +S P A + +ATSG
Sbjct: 441 FVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE--STPVHSSPVATATTPPPARSATSGHV 498
Query: 659 QGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNH----- 713
+ S S PE+S +G + A G + H ++ H
Sbjct: 499 EESTAYHRSPGSTQTMHFPESSTTSGHSEES-ATFHGSTTHTKSSTPSTTAALAHTSYHS 557
Query: 714 --GDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIS 771
G + D+ +S G K ++ P T S+PS +
Sbjct: 558 SLGSTETTHFRDSSTIS-----------GRSEESKASHSSPDAMATTVLPAGSTPSVLVG 606
Query: 772 TATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPS 831
+TPSP S+ ++ ++ GL + +S LP AS S+ S
Sbjct: 607 DSTPSPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSPDTTHLP-ASMTSSGVSEES 664
Query: 832 MSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPT 872
+ P ST + GLS P P T
Sbjct: 665 TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 705
Score = 35.8 bits (81), Expect = 0.29
Identities = 59/310 (19%), Positives = 112/310 (36%), Gaps = 43/310 (13%)
Query: 573 LNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQ----PLFSTGSAQYHQATSTGIKKA 628
++S + E S + GL + ++ S P P +T S ++T++ +
Sbjct: 4308 ISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG 4367
Query: 629 NEHLT-LPSNSVPQGDADSHLSCH---------------TATSGGQQGIMFTKESKPSKN 672
+ H T PS++ G + + H TA+S G + F S S
Sbjct: 4368 SMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTF-HSSPGSTE 4426
Query: 673 RSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADN-------- 724
+L+P+ + +G V + H ++ A S+ G+S N
Sbjct: 4427 TTLLPDNTTASG-LLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAP 4485
Query: 725 PQLSALLIGKANGNVGTGTCDKVNNIHPAVHT--KTDHSVASSPSSAISTATPSP----- 777
P ++ + + + G+ + + + T +++ S S + TPSP
Sbjct: 4486 PTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTT 4545
Query: 778 ------KSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPS 831
+T S S +++ P S + GE S SST + A +++ +
Sbjct: 4546 SGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEP 4605
Query: 832 MSVSICPSST 841
S P ST
Sbjct: 4606 TSYHSSPGST 4615
Score = 35.0 bits (79), Expect = 0.49
Identities = 78/325 (24%), Positives = 132/325 (40%), Gaps = 41/325 (12%)
Query: 529 GTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNS 588
G S+I GST +G N + S + + P+ + + + + T + ST + L +S
Sbjct: 160 GFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGV--SVTFITGSTAT--KHFLDSS 215
Query: 589 AQGLHKSQSSCL-SGPNEEQPLFSTGSAQY--HQATSTGIKKANEHLTLPSNSVPQGDAD 645
H +S+ SGP +TG+ + H ATS + E T P S
Sbjct: 216 TNSGHSEESTVSHSGPG------ATGTTLFPSHSATSVFV---GEPKTSPITSASM--ET 264
Query: 646 SHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIA 705
+ L T T+G + S S +R+L P + TS+G ++ K ++H
Sbjct: 265 TALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART-----TSSGVSE-KSTTSHSRPGPT 318
Query: 706 DAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASS 765
++ P+ P ++ S + G + + GT +++ P + T H SS
Sbjct: 319 HTIAFPDSTTMPG--VSQESTASHSIPGSTDTTLSPGTTTP-SSLGP--ESTTFH---SS 370
Query: 766 PSSAISTATPSPKSTE---QRSINSVTSLNSPHSGLH-----TVNGEGLG-KSQSSTKVD 816
P +T P +T + S +S SPH+ L T GE +S S+K
Sbjct: 371 PGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTFQSWPSSKDT 430
Query: 817 LPLASHRSTSQILPSMSVSICPSST 841
P S +++ + S + PSST
Sbjct: 431 SPAPSGTTSAFVKLSTTYHSSPSST 455
Score = 34.3 bits (77), Expect = 0.83
Identities = 83/377 (22%), Positives = 134/377 (35%), Gaps = 57/377 (15%)
Query: 477 ITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGS 536
+ ++S+P +S S R PH L+ S ++ G S S P + +
Sbjct: 744 LLEASMPVHS-STRSPHTTLSPAGSTTRQGESTT-----FHSWPSSKDTRPAPPT----T 793
Query: 537 TDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSST-----EEPWRKQLSNSAQG 591
T + S GS S+ +P H S+T E S Q
Sbjct: 794 TSAFVEPSTTSHGSPSS------------IPTTHISARSTTSGLVEESTTYHSSPGSTQT 841
Query: 592 LHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCH 651
+H +S SG EE S S + +++ A +S P A +H
Sbjct: 842 MHFPESDTTSGRGEESTT-SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 900
Query: 652 TATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSP 711
+ TSG + + S+ + ++P +R T G + +S+ + A S+
Sbjct: 901 STTSGRSEESTASHSSQDATGTIVLP--ARSTTSVLLGESTTSPISSGSMETTALPGSTT 958
Query: 712 NHGDSP-NLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAI 770
G S + +P+ A + A+ +G ++ S P S
Sbjct: 959 TPGLSERSTTFHSSPRSPATTLSPAS-TTSSGVSEESTTSR------------SRPGSTH 1005
Query: 771 STATPSPKSTEQRSINSVTSLNSPHS---GLHTVNGEGLGKSQSSTKVDLPLASHRSTSQ 827
+TA P +T S +S TS +SP S L + G SQ ST SH S+
Sbjct: 1006 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST------TSHSSSG- 1058
Query: 828 ILPSMSVSICPSSTEVL 844
S ++ P ST L
Sbjct: 1059 ---STDTALSPGSTTAL 1072
Score = 33.1 bits (74), Expect = 1.8
Identities = 65/304 (21%), Positives = 115/304 (37%), Gaps = 30/304 (9%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P T ++T++ + +
Sbjct: 3869 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLS------PASMTSLGVGEESTTSRSQPGST 3922
Query: 631 HLTL-PSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNG 689
H T+ P+++ G ++ + ++++ G + +F + + S R T+ H+ S
Sbjct: 3923 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRRE--EPTTFHSRPASTH 3980
Query: 690 C------ADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGT 743
+ GL+ + +S G L AD + S ++G+ GT
Sbjct: 3981 TTLFTEDSTTSGLTEE-STAFPGSPASTQTGLPATLTTADLGEESTTF-PSSSGSTGTKL 4038
Query: 744 CDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHS-----GL 798
+ V T + SPSS +T P +T S S T SP S
Sbjct: 4039 SPARSTTSGLVGESTPSRL--SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 4096
Query: 799 HTVNGEGLGKSQSSTKVDLPLASHR-----STSQILPSMSVSICPSSTEVLKACRNPGKN 853
T G+ + +SST P ++H ST+ S + SS +A +PG
Sbjct: 4097 ATTTSSGVSE-ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGST 4155
Query: 854 GLSN 857
S+
Sbjct: 4156 TASS 4159
Score = 32.0 bits (71), Expect = 4.1
Identities = 65/307 (21%), Positives = 116/307 (37%), Gaps = 36/307 (11%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P T ++T++ + +
Sbjct: 2786 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLS------PASMTSLGVGEESTTSRSQPGST 2839
Query: 631 HLTL-PSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPS---------KNRSLVPETS 680
H T+ P+++ G ++ + ++++ G + +F + + S +R T+
Sbjct: 2840 HSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTT 2899
Query: 681 RHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVG 740
T D++ GL+ + +S G L AD + S ++G+ G
Sbjct: 2900 LFTEDSTTS-----GLTEE-STAFPGSPASTQTGLPATLTTADLGEESTTF-PSSSGSTG 2952
Query: 741 TGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHS---- 796
T + V T + SPSS +T P +T S S T SP S
Sbjct: 2953 TTLSPARSTTSGLVGESTPSRL--SPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT 3010
Query: 797 -GLHTVNGEGLGKSQSSTKVDLPLASHR-----STSQILPSMSVSICPSSTEVLKACRNP 850
T G+ + +SST P ++H ST+ S + SS +A +P
Sbjct: 3011 LSPATTTSSGVSE-ESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSP 3069
Query: 851 GKNGLSN 857
G S+
Sbjct: 3070 GSTTASS 3076
Score = 31.6 bits (70), Expect = 5.4
Identities = 68/313 (21%), Positives = 116/313 (37%), Gaps = 48/313 (15%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P T ++T++ + +
Sbjct: 1229 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLS------PASMTSLGVGEESTTSRSQPGST 1282
Query: 631 HLTL-PSNSVPQGDADSHLSCHTATSGGQQGIMF--------------TKESKP-SKNRS 674
H T+ P+++ G ++ + ++++ G + +F T S+P S + +
Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342
Query: 675 LVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGK 734
L E S +G T A + +S G L AD + S
Sbjct: 1343 LFTEDSTTSGLTEESTA------------FPGSPASTQTGLPATLTTADLGEESTTF-PS 1389
Query: 735 ANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++G+ GT + V T + SPSS +T P +T S S T SP
Sbjct: 1390 SSGSTGTKLSPARSTTSGLVGESTPSRL--SPSSTETTTLPGSPTTPSLSEKSTTFYTSP 1447
Query: 795 HS-----GLHTVNGEGLGKSQSSTKVDLPLASHR-----STSQILPSMSVSICPSSTEVL 844
S T G+ + +SST P ++H ST+ S + SS
Sbjct: 1448 RSPDATLSPATTTSSGVSE-ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST 1506
Query: 845 KACRNPGKNGLSN 857
+A +PG S+
Sbjct: 1507 EATLSPGSTTASS 1519
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 50.1 bits (118), Expect = 1e-05
Identities = 75/325 (23%), Positives = 118/325 (36%), Gaps = 33/325 (10%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P +T S ++T++ + +
Sbjct: 438 TALPGSTTTPGLSERSTTFHSSPRSPATTLS------PASTTSSGVSEESTTSRSRPGST 491
Query: 631 HLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGC 690
H T + P LS H+ TS G T P+ + P T +S+G
Sbjct: 492 HTT----AFPDSTTTPGLSRHSTTSHSSPGSTDTT-LLPASTTTSGPSQESTTSHSSSGS 546
Query: 691 ADVKGLSNHVHQLIADAVSSPNH---GDSPNLLIADNPQLSALLIGKANGNVGTG----T 743
D L S+ H G + L D+ S ++ + TG T
Sbjct: 547 TDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 606
Query: 744 CDKVNNIHPAV---------HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++ P + H + H+ S PS+A TA +T RS S + + P
Sbjct: 607 LSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTA--TAPVEESTTYHRSPGSTPTTHFP 664
Query: 795 HSGLHTVNGEGLGKSQSSTKVD--LPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGK 852
S + + E SS P ++H +TS S + I P STE+ +
Sbjct: 665 ASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTT 724
Query: 853 NGLSNSCILLDKCPPPRPPTSPYPP 877
GLS + PR PT+ P
Sbjct: 725 PGLSEASTTF--YSSPRSPTTTLSP 747
Score = 40.8 bits (94), Expect = 0.009
Identities = 66/319 (20%), Positives = 109/319 (34%), Gaps = 32/319 (10%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + + THT+ + ++ EEP S S H
Sbjct: 324 GSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTH 383
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTL-----PSNSVPQGDADSHL 648
SS SG +EE ST S AT T + A ++ ++ + G ++
Sbjct: 384 FPDSSTTSGRSEE----STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 439
Query: 649 SCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAV 708
+ T+ G T S P + + S TS+G ++
Sbjct: 440 LPGSTTTPGLSERSTTFHSSPRSPATTLSPAST----TSSGVSE------------ESTT 483
Query: 709 SSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCD------KVNNIHPAVHTKTDHSV 762
S G + D+ L + G+ D P+ + T HS
Sbjct: 484 SRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSS 543
Query: 763 ASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASH 822
+ S +A+S + + S Q S ++ S H+ L + G ++ST+V S
Sbjct: 544 SGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSP 603
Query: 823 RSTSQILPSMSVSICPSST 841
R+T S S + ST
Sbjct: 604 RTTLSPASSTSPGLQGEST 622
Score = 34.3 bits (77), Expect = 0.83
Identities = 83/377 (22%), Positives = 134/377 (35%), Gaps = 57/377 (15%)
Query: 477 ITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGS 536
+ ++S+P +S S R PH L+ S ++ G S S P + +
Sbjct: 231 LLEASMPVHS-STRSPHTTLSPAGSTTRQGESTT-----FHSWPSSKDTRPAPPT----T 280
Query: 537 TDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSST-----EEPWRKQLSNSAQG 591
T + S GS S+ +P H S+T E S Q
Sbjct: 281 TSAFVEPSTTSHGSPSS------------IPTTHISARSTTSGLVEESTTYHSSPGSTQT 328
Query: 592 LHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCH 651
+H +S SG EE S S + +++ A +S P A +H
Sbjct: 329 MHFPESDTTSGRGEESTT-SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 387
Query: 652 TATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSP 711
+ TSG + + S+ + ++P +R T G + +S+ + A S+
Sbjct: 388 STTSGRSEESTASHSSQDATGTIVLP--ARSTTSVLLGESTTSPISSGSMETTALPGSTT 445
Query: 712 NHGDSP-NLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAI 770
G S + +P+ A + A+ +G ++ S P S
Sbjct: 446 TPGLSERSTTFHSSPRSPATTLSPAS-TTSSGVSEESTTSR------------SRPGSTH 492
Query: 771 STATPSPKSTEQRSINSVTSLNSPHS---GLHTVNGEGLGKSQSSTKVDLPLASHRSTSQ 827
+TA P +T S +S TS +SP S L + G SQ ST SH S+
Sbjct: 493 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST------TSHSSSG- 545
Query: 828 ILPSMSVSICPSSTEVL 844
S ++ P ST L
Sbjct: 546 ---STDTALSPGSTTAL 559
Score = 33.5 bits (75), Expect = 1.4
Identities = 35/128 (27%), Positives = 53/128 (41%), Gaps = 5/128 (3%)
Query: 755 HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS-- 812
H+ T H+++S PS+ ++A ++ S S+ + + P S + E S SS
Sbjct: 1431 HSSTTHTISSPPST--TSALVEEPTSYHSSPGSIATTHFPESSTTSGRSEESTASHSSPD 1488
Query: 813 TKVDLPLASHRSTS-QILPSMSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPP 871
T PL +H +TS +I S + I P S E A + S IL P
Sbjct: 1489 TNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYTSDLVGEPT 1548
Query: 872 TSPYPPLP 879
T P P
Sbjct: 1549 TFYISPSP 1556
Score = 31.6 bits (70), Expect = 5.4
Identities = 68/313 (21%), Positives = 116/313 (37%), Gaps = 48/313 (15%)
Query: 571 TDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANE 630
T L ST P + S + +S ++ LS P T ++T++ + +
Sbjct: 716 TTLPGSTTTPGLSEASTTFYSSPRSPTTTLS------PASMTSLGVGEESTTSRSQPGST 769
Query: 631 HLTL-PSNSVPQGDADSHLSCHTATSGGQQGIMF--------------TKESKP-SKNRS 674
H T+ P+++ G ++ + ++++ G + +F T S+P S + +
Sbjct: 770 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 829
Query: 675 LVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGK 734
L E S +G T A + +S G L AD + S
Sbjct: 830 LFTEDSTTSGLTEESTA------------FPGSPASTQTGLPATLTTADLGEESTTF-PS 876
Query: 735 ANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSP 794
++G+ GT + V T + SPSS +T P +T S S T SP
Sbjct: 877 SSGSTGTKLSPARSTTSGLVGESTPSRL--SPSSTETTTLPGSPTTPSLSEKSTTFYTSP 934
Query: 795 HS-----GLHTVNGEGLGKSQSSTKVDLPLASHR-----STSQILPSMSVSICPSSTEVL 844
S T G+ + +SST P ++H ST+ S + SS
Sbjct: 935 RSPDATLSPATTTSSGVSE-ESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGST 993
Query: 845 KACRNPGKNGLSN 857
+A +PG S+
Sbjct: 994 EATLSPGSTTASS 1006
>gi|25952122 Bardet-Biedl syndrome 4 [Homo sapiens]
Length = 519
Score = 48.5 bits (114), Expect = 4e-05
Identities = 50/246 (20%), Positives = 102/246 (41%), Gaps = 21/246 (8%)
Query: 93 FCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQD 152
+ LG +LL D KA+ Y++ + N L LGL+Y + A + +
Sbjct: 171 YIMLGKIHLLEGDLDKAIEVYKKAVEFSPE---NTELLTTLGLLYLQLGIYQKAFEHLGN 227
Query: 153 VLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLY 212
L DP+ +A L G M + + D+ +L ++ ++ C + + +I +
Sbjct: 228 ALTYDPTNYKA---ILAAGSMMQTHGDFDVALTKYR--VVAC--AVPESPPLWNNIGMCF 280
Query: 213 ETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQK 272
++KY +A L+ N A +L LG +H M + + A +L
Sbjct: 281 FGKKKYVAAISC----LKRANYLAPFDWKILYNLGLVHLTMQ-------QYASAFHFLSA 329
Query: 273 SLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPM 332
++ P G+ + L +++ +++A +Y +++ + + + VL Q +
Sbjct: 330 AINFQPKMGELYMLLAVALTNLEDIENAKRAYAEAVHLDKCNPLVNLNYAVLLYNQGEKK 389
Query: 333 DALQAY 338
+AL Y
Sbjct: 390 NALAQY 395
>gi|118766328 transmembrane and tetratricopeptide repeat containing
4 isoform 2 [Homo sapiens]
Length = 741
Score = 47.0 bits (110), Expect = 1e-04
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 24/200 (12%)
Query: 170 LGLMFKVNT--------DYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSA 221
LG++F +NT +++S + F+ AL C NA++ ++I + +A
Sbjct: 447 LGILF-INTLRCVLRSGEWRSEEQLFRSALSVCP----LNAKVHYNIGKNLADKGNQTAA 501
Query: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSG 281
Y + ++ P V A +N+ + + + A + L +++ P+
Sbjct: 502 IRYYREAVRLN--PKYVHAM---------NNLGNILKERNELQEAEELLSLAVQIQPDFA 550
Query: 282 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICA 341
+W LG +S+ + + A SYR +I D + ++G LY N+ +DAL A+ A
Sbjct: 551 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNA 610
Query: 342 VQLDHGHAAAWMDLGTLYES 361
L H+ AW ++ L ++
Sbjct: 611 TVLKPEHSLAWNNMIILLDN 630
Score = 45.1 bits (105), Expect = 5e-04
Identities = 27/113 (23%), Positives = 55/113 (48%)
Query: 268 QYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 327
Q + +L P + + Y +G+ + G A YR+++ + ++G + ++
Sbjct: 469 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 528
Query: 328 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKR 380
+N+ +A + AVQ+ AAAWM+LG + S + + A + Y A + +R
Sbjct: 529 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRR 581
Score = 40.0 bits (92), Expect = 0.015
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Query: 249 MHHNMDL-VGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQS 307
+H+N+ + DK + + AI+Y ++++ +P + LG ++Q+A +
Sbjct: 484 VHYNIGKNLADKGNQTA-AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLA 542
Query: 308 IDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQD 367
+ A W ++G++ + A Q+Y A++ + + +LG LY N+ D
Sbjct: 543 VQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVD 602
Query: 368 AIKCYLNA 375
A+ + NA
Sbjct: 603 ALNAWRNA 610
>gi|118766330 transmembrane and tetratricopeptide repeat containing
4 isoform 1 [Homo sapiens]
Length = 760
Score = 47.0 bits (110), Expect = 1e-04
Identities = 46/200 (23%), Positives = 90/200 (45%), Gaps = 24/200 (12%)
Query: 170 LGLMFKVNT--------DYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSA 221
LG++F +NT +++S + F+ AL C NA++ ++I + +A
Sbjct: 466 LGILF-INTLRCVLRSGEWRSEEQLFRSALSVCP----LNAKVHYNIGKNLADKGNQTAA 520
Query: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSG 281
Y + ++ P V A +N+ + + + A + L +++ P+
Sbjct: 521 IRYYREAVRLN--PKYVHAM---------NNLGNILKERNELQEAEELLSLAVQIQPDFA 569
Query: 282 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICA 341
+W LG +S+ + + A SYR +I D + ++G LY N+ +DAL A+ A
Sbjct: 570 AAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVDALNAWRNA 629
Query: 342 VQLDHGHAAAWMDLGTLYES 361
L H+ AW ++ L ++
Sbjct: 630 TVLKPEHSLAWNNMIILLDN 649
Score = 45.1 bits (105), Expect = 5e-04
Identities = 27/113 (23%), Positives = 55/113 (48%)
Query: 268 QYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQ 327
Q + +L P + + Y +G+ + G A YR+++ + ++G + ++
Sbjct: 488 QLFRSALSVCPLNAKVHYNIGKNLADKGNQTAAIRYYREAVRLNPKYVHAMNNLGNILKE 547
Query: 328 QNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAARSKR 380
+N+ +A + AVQ+ AAAWM+LG + S + + A + Y A + +R
Sbjct: 548 RNELQEAEELLSLAVQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRR 600
Score = 40.0 bits (92), Expect = 0.015
Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 2/128 (1%)
Query: 249 MHHNMDL-VGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQS 307
+H+N+ + DK + + AI+Y ++++ +P + LG ++Q+A +
Sbjct: 503 VHYNIGKNLADKGNQTA-AIRYYREAVRLNPKYVHAMNNLGNILKERNELQEAEELLSLA 561
Query: 308 IDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQD 367
+ A W ++G++ + A Q+Y A++ + + +LG LY N+ D
Sbjct: 562 VQIQPDFAAAWMNLGIVQNSLKRFEAAEQSYRTAIKHRRKYPDCYYNLGRLYADLNRHVD 621
Query: 368 AIKCYLNA 375
A+ + NA
Sbjct: 622 ALNAWRNA 629
>gi|7662078 tetratricopeptide repeat domain 37 [Homo sapiens]
Length = 1564
Score = 47.0 bits (110), Expect = 1e-04
Identities = 28/98 (28%), Positives = 46/98 (46%), Gaps = 2/98 (2%)
Query: 266 AIQYLQKSLEADPNSGQSWYFLG--RCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGV 323
++ L+K++ D N+ W LG CYS IG A + +SI + +A W ++GV
Sbjct: 810 SLHCLKKAVRLDSNNHLYWNALGVVACYSGIGNYALAQHCFIKSIQSEQINAVAWTNLGV 869
Query: 324 LYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYES 361
LY A +A+ A LD + W+ + E+
Sbjct: 870 LYLTNENIEQAHEAFKMAQSLDPSYLMCWIGQALIAEA 907
Score = 35.4 bits (80), Expect = 0.37
Identities = 18/48 (37%), Positives = 22/48 (45%)
Query: 316 DTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCN 363
+ W IGV + QP A AY A +L+ AW L LYE N
Sbjct: 41 NAWVFIGVAAAELEQPDQAQSAYKKAAELEPDQLLAWQGLANLYEKYN 88
Score = 31.2 bits (69), Expect = 7.0
Identities = 16/76 (21%), Positives = 38/76 (50%), Gaps = 2/76 (2%)
Query: 254 DLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEA 313
D + +K KE A+++ + L+ + N+ +W F+G + + + A +Y+++ +
Sbjct: 15 DAIRNKEYKE--ALKHCKTVLKQEKNNYNAWVFIGVAAAELEQPDQAQSAYKKAAELEPD 72
Query: 314 SADTWCSIGVLYQQQN 329
W + LY++ N
Sbjct: 73 QLLAWQGLANLYEKYN 88
>gi|224028289 tetratricopeptide repeat domain 28 [Homo sapiens]
Length = 2481
Score = 46.6 bits (109), Expect = 2e-04
Identities = 72/340 (21%), Positives = 139/340 (40%), Gaps = 31/340 (9%)
Query: 72 KAVRCYESLILKAEGK----VESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNA 127
+AV+ YE + A+ ++ +C LG L ++SKA + SL +
Sbjct: 652 EAVKYYEQDLALAKDLHDKLSQAKAYCNLGLAFKALLNFSKAEECQKYLLSLAQSLNNSQ 711
Query: 128 A---FLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAK---EIHLRLGLMFKVNTDYK 181
A L LG ++ + AIK ++ L + + + LG +++ Y
Sbjct: 712 AKFRALGNLGDIFICKKDINGAIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYD 771
Query: 182 SSLKHFQLALIDCNPCTLSNAEIQFH--IAHLYETQRKYHSAKEAYEQLLQTENL--PAQ 237
+L + L + E + H +A +Y KY A + YE+ L
Sbjct: 772 KALGYHTQELEVYQELSDLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPS 831
Query: 238 VKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQK--SLEADPNSGQSWYFLGRCYSSIG 295
++A V +G NM+++ + + LQ+ E+ + G+++ LG CY ++G
Sbjct: 832 LEAQVYGNMGITKMNMNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALG 891
Query: 296 KVQDA------FISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDH--- 346
++A ++S QS+++ + A + +G ++ AL + + + H
Sbjct: 892 DYEEAIKYYEQYLSVAQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELG 951
Query: 347 ---GHAAAWMDLGTLYESCNQPQDAIKC---YLNAARSKR 380
A A+ +LG+L+ + AI C LN AR +
Sbjct: 952 EAFNKAQAYGELGSLHSQLGNYEQAISCLERQLNIARDMK 991
Score = 46.2 bits (108), Expect = 2e-04
Identities = 72/332 (21%), Positives = 133/332 (40%), Gaps = 42/332 (12%)
Query: 73 AVRCYESLILKA----EGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYSLQADYWKNAA 128
A++ YE + A + ++E+ + LG +++ Y KAL Y++ + + ++ +
Sbjct: 733 AIKFYEQQLGLAHQVKDRRLEASAYAALGTAYRMIQKYDKALG----YHTQELEVYQELS 788
Query: 129 FLYG-------LGLVYFYYNAFHWAIKAFQDVLYV-----DPSFCRAKEIHLRLGLMFKV 176
L G L VY + A K +++ L + DPS +++ +G+
Sbjct: 789 DLPGECRAHGHLAAVYMALGKYTMAFKCYEEQLDLGQKLKDPSL--EAQVYGNMGITKMN 846
Query: 177 NTDYKSSLKHF--QLALIDC---NPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQT 231
+ ++ +F QLA++ N L ++ YE Y A + YEQ L
Sbjct: 847 MNVMEEAIGYFEQQLAMLQQLSGNESVLDRGRAYGNLGDCYEALGDYEEAIKYYEQYLSV 906
Query: 232 ENL--PAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGR 289
Q +A + LG H M + + + EA N Q++ LG
Sbjct: 907 AQSLNRMQDQAKAYRGLGNGHRAMGSLQQALVCFEKRLVVAHELGEAF-NKAQAYGELGS 965
Query: 290 CYSSIGKVQDAFISYRQSID-----KSEA-SADTWCSIGVLYQQQNQPMDALQAYICAVQ 343
+S +G + A + ++ K A +D C +G +YQQ + ALQ + +Q
Sbjct: 966 LHSQLGNYEQAISCLERQLNIARDMKDRALESDAACGLGGVYQQMGEYDTALQYHQLDLQ 1025
Query: 344 LDHG------HAAAWMDLGTLYESCNQPQDAI 369
+ A+ +LG YES + A+
Sbjct: 1026 IAEETNNPTCQGRAYGNLGLTYESLGTFERAV 1057
>gi|167466177 cell division cycle protein 27 isoform 1 [Homo
sapiens]
Length = 830
Score = 44.7 bits (104), Expect = 6e-04
Identities = 44/161 (27%), Positives = 75/161 (46%), Gaps = 19/161 (11%)
Query: 96 LGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLY 155
LGH +L E+ KAL+ ++ + ++ NA YGLG++Y+ F A FQ L
Sbjct: 613 LGHEFVLTEELDKALACFRNAIRVNPRHY-NA--WYGLGMIYYKQEKFSLAEMHFQKALD 669
Query: 156 VDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTL---SNAEIQFHIAHLY 212
++P ++ + +G++ + +LK + AL N + N +FH A +
Sbjct: 670 INP---QSSVLLCHIGVV-------QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL 719
Query: 213 ETQRKYHSAKEAYEQLLQ---TENLPAQVKATVLQQLGWMH 250
KY SA + E+L Q E+L + V ++LG H
Sbjct: 720 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 760
Score = 37.4 bits (85), Expect = 0.098
Identities = 19/69 (27%), Positives = 35/69 (50%)
Query: 309 DKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDA 368
D + S + WC+ G + Q + A++ + A+Q+D +A A+ LG + + A
Sbjct: 567 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 626
Query: 369 IKCYLNAAR 377
+ C+ NA R
Sbjct: 627 LACFRNAIR 635
Score = 37.0 bits (84), Expect = 0.13
Identities = 50/258 (19%), Positives = 102/258 (39%), Gaps = 24/258 (9%)
Query: 119 LQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNT 178
L + ++ L +G YF + + A + F +V ++ EI+ ++ +
Sbjct: 497 LPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT--LWHLQK 554
Query: 179 DYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQV 238
D S+ L +D N + E + + QR++ A + +++ +Q + P
Sbjct: 555 DVALSVLSKDLTDMDKN-----SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD--PNYA 607
Query: 239 KATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQ 298
A L + H L + A+ + ++ +P +WY LG Y K
Sbjct: 608 YAYTL-----LGHEFVLTEEL----DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS 658
Query: 299 DAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD------HGHAAAW 352
A + +++++D + S+ C IGV+ + AL A+ +D H A+
Sbjct: 659 LAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASV 718
Query: 353 MDLGTLYESCNQPQDAIK 370
+ Y+S Q + +K
Sbjct: 719 LFANEKYKSALQELEELK 736
>gi|167466175 cell division cycle protein 27 isoform 2 [Homo
sapiens]
Length = 824
Score = 44.7 bits (104), Expect = 6e-04
Identities = 44/161 (27%), Positives = 75/161 (46%), Gaps = 19/161 (11%)
Query: 96 LGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLY 155
LGH +L E+ KAL+ ++ + ++ NA YGLG++Y+ F A FQ L
Sbjct: 607 LGHEFVLTEELDKALACFRNAIRVNPRHY-NA--WYGLGMIYYKQEKFSLAEMHFQKALD 663
Query: 156 VDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTL---SNAEIQFHIAHLY 212
++P ++ + +G++ + +LK + AL N + N +FH A +
Sbjct: 664 INP---QSSVLLCHIGVV-------QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVL 713
Query: 213 ETQRKYHSAKEAYEQLLQ---TENLPAQVKATVLQQLGWMH 250
KY SA + E+L Q E+L + V ++LG H
Sbjct: 714 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 754
Score = 37.4 bits (85), Expect = 0.098
Identities = 19/69 (27%), Positives = 35/69 (50%)
Query: 309 DKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDA 368
D + S + WC+ G + Q + A++ + A+Q+D +A A+ LG + + A
Sbjct: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620
Query: 369 IKCYLNAAR 377
+ C+ NA R
Sbjct: 621 LACFRNAIR 629
Score = 37.0 bits (84), Expect = 0.13
Identities = 50/258 (19%), Positives = 102/258 (39%), Gaps = 24/258 (9%)
Query: 119 LQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNT 178
L + ++ L +G YF + + A + F +V ++ EI+ ++ +
Sbjct: 491 LPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT--LWHLQK 548
Query: 179 DYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQV 238
D S+ L +D N + E + + QR++ A + +++ +Q + P
Sbjct: 549 DVALSVLSKDLTDMDKN-----SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD--PNYA 601
Query: 239 KATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQ 298
A L + H L + A+ + ++ +P +WY LG Y K
Sbjct: 602 YAYTL-----LGHEFVLTEEL----DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS 652
Query: 299 DAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLD------HGHAAAW 352
A + +++++D + S+ C IGV+ + AL A+ +D H A+
Sbjct: 653 LAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASV 712
Query: 353 MDLGTLYESCNQPQDAIK 370
+ Y+S Q + +K
Sbjct: 713 LFANEKYKSALQELEELK 730
>gi|89026265 PREDICTED: mucin 12 [Homo sapiens]
Length = 978
Score = 42.0 bits (97), Expect = 0.004
Identities = 67/302 (22%), Positives = 103/302 (34%), Gaps = 36/302 (11%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + A S + THT+ + ++ EEP S S H
Sbjct: 256 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTH 315
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNS-------VPQGDADS 646
+SS SG +EE +A + + GI H T + G ++
Sbjct: 316 FPESSTTSGRSEES------TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 369
Query: 647 HLSCHTATSG--GQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLI 704
L+ T T G + I+++ P + S TS +S L
Sbjct: 370 TLASTTTTPGLSAKSTILYSSSRSPDQTLSPASMTS-------------SSISGEPTSLY 416
Query: 705 ADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVAS 764
+ A S+ + + Q S K T + + A T HS
Sbjct: 417 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHS--- 473
Query: 765 SPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTV----NGEGLGKSQSSTKVDLPLA 820
P SA+ST +P+ + S S T +SP S T N + QS+ D P
Sbjct: 474 QPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGF 533
Query: 821 SH 822
+H
Sbjct: 534 TH 535
>gi|239758148 PREDICTED: similar to mucin 11 [Homo sapiens]
Length = 587
Score = 41.2 bits (95), Expect = 0.007
Identities = 62/281 (22%), Positives = 99/281 (35%), Gaps = 12/281 (4%)
Query: 563 THTLPHNHTDLNSSTEEPWRKQLS-NSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQAT 621
THT+ + ++ EEP S S H SS SG +EE ST S AT
Sbjct: 24 THTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEE----STASHSSQDAT 79
Query: 622 STGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSR 681
T + A ++ S TA G +++S + P T+
Sbjct: 80 GTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTL 139
Query: 682 HTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGT 741
T++ + ++H + P+ +P L S+ G+ T
Sbjct: 140 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSS------PGSTDT 193
Query: 742 GTCD-KVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHT 800
P+ + T HS S +A+S + + S Q S +S S H+ L
Sbjct: 194 TLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFP 253
Query: 801 VNGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSST 841
+ G ++ST+V S R+T S S + ST
Sbjct: 254 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGEST 294
Score = 32.0 bits (71), Expect = 4.1
Identities = 57/266 (21%), Positives = 92/266 (34%), Gaps = 42/266 (15%)
Query: 562 NTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQA 620
+THT P + + EE S S H SS SG +E+ +F
Sbjct: 302 STHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF---------- 351
Query: 621 TSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETS 680
+S P + S H+ TSG ++ES S ++ T+
Sbjct: 352 ----------------HSSPDASGTTPSSAHSTTSG------VSEESSTSHSQPGSTHTT 389
Query: 681 RHTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVG 740
T+ + ++H Q +A SP A ++S + +
Sbjct: 390 AFPDSTTTSGLSQEPTTSHSSQGSTEATLDTT--PSPPGTTAAPVEVSTTYHSRPSSTPT 447
Query: 741 TGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHT 800
T + + + T HS SP S +TA P +T S S T +SP S T
Sbjct: 448 THFSASSTTLGRSEESTTVHS---SPGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTT 504
Query: 801 VNGEGLGKS----QSSTKVDLPLASH 822
++ S +S+T P ++H
Sbjct: 505 LSPASTTSSGVSEESTTSHSRPGSTH 530
Score = 31.2 bits (69), Expect = 7.0
Identities = 76/373 (20%), Positives = 132/373 (35%), Gaps = 44/373 (11%)
Query: 530 TSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWR--KQLSN 587
TS +LG + T + S + + G+ T L T +SS P S
Sbjct: 90 TSVLLGESTTSPISSGSMETTALPGST-----TTPGLSEKSTTFHSSPRSPATTLSPAST 144
Query: 588 SAQGLHKSQSSCLSGPNEEQPLF-----STGSAQYHQATSTGIKKANEHLTLPSNSVPQG 642
++ G+ + ++ S P +T H TS + + LP+++ G
Sbjct: 145 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 204
Query: 643 DADSHLSCH---------------TATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTS 687
+ + H TA S GQ+ F S S + +L P+++ TS
Sbjct: 205 PSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTF-HSSPGSTHTTLFPDST-----TS 258
Query: 688 NGCADVKGLSNHVHQLIAD--AVSSPNHGDSPNLL---IADNPQLSALLIGKANGNVGTG 742
+G + S VH SP SP L A ++ + + T
Sbjct: 259 SGIVEA---STRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATA 315
Query: 743 TCDKVNNIHPAV-HTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTV 801
++ H + T T H ASS +S S + S+ S + +S +S SG+
Sbjct: 316 PVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGVSEE 375
Query: 802 NGEGLGKSQSSTKVDLPLASHRSTSQILPSMSVSICPSSTEVLKACRNPGKNGLSNSCIL 861
+ + S+ P ++ S P+ S S S+ L P G + + +
Sbjct: 376 SSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLDT--TPSPPGTTAAPVE 433
Query: 862 LDKCPPPRPPTSP 874
+ RP ++P
Sbjct: 434 VSTTYHSRPSSTP 446
>gi|53759120 tetratricopeptide repeat domain 8 isoform A [Homo
sapiens]
Length = 515
Score = 41.2 bits (95), Expect = 0.007
Identities = 21/90 (23%), Positives = 44/90 (48%)
Query: 283 SWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAV 342
++ +L + Y S+ + A ++Q +DK C I +Y++ N A + Y +
Sbjct: 260 TFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVL 319
Query: 343 QLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
+ D+ H A +G+ + +QP+ A++ Y
Sbjct: 320 KQDNTHVEAIACIGSNHFYSDQPEIALRFY 349
Score = 38.1 bits (87), Expect = 0.057
Identities = 21/103 (20%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 273 SLEADPNSGQSWYF---LGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQN 329
+L + + + W++ +G+CY +G ++A ++ ++ K + DT+ + +Y +
Sbjct: 214 ALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSAL-KQQEMVDTFLYLAKVYVSLD 272
Query: 330 QPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
QP+ AL + + G + +YE N A + Y
Sbjct: 273 QPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYY 315
Score = 31.6 bits (70), Expect = 5.4
Identities = 58/260 (22%), Positives = 103/260 (39%), Gaps = 28/260 (10%)
Query: 22 MAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLI 81
+A+ S + +++L + + G + L G R++E+ + A Y+ ++
Sbjct: 264 LAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEE----MNNMSSAAEYYKEVL 319
Query: 82 LKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYS--LQADYWKNAAFLYGLGLVYFY 139
+ VE+ HF YS R+Y LQ + N LGL FY
Sbjct: 320 KQDNTHVEAIACIGSNHF------YSDQPEIALRFYRRLLQMGIY-NGQLFNNLGLCCFY 372
Query: 140 YNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTL 199
+ + +F+ L + + A ++ LG + D + + F+LAL++ N
Sbjct: 373 AQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN---- 428
Query: 200 SNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDK 259
++AE ++A L RK H E LLQT +++ + H N + DK
Sbjct: 429 NHAEAYNNLAVL--EMRKGH--VEQARALLQT-------ASSLAPHMYEPHFNFATISDK 477
Query: 260 ATKESYAIQYLQKSLEADPN 279
+ QKS A P+
Sbjct: 478 IGDLQRSYVAAQKSEAAFPD 497
>gi|38146008 tetratricopeptide repeat domain 8 isoform C [Homo
sapiens]
Length = 475
Score = 41.2 bits (95), Expect = 0.007
Identities = 21/90 (23%), Positives = 44/90 (48%)
Query: 283 SWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAV 342
++ +L + Y S+ + A ++Q +DK C I +Y++ N A + Y +
Sbjct: 220 TFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVL 279
Query: 343 QLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
+ D+ H A +G+ + +QP+ A++ Y
Sbjct: 280 KQDNTHVEAIACIGSNHFYSDQPEIALRFY 309
Score = 38.1 bits (87), Expect = 0.057
Identities = 21/103 (20%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 273 SLEADPNSGQSWYF---LGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQN 329
+L + + + W++ +G+CY +G ++A ++ ++ K + DT+ + +Y +
Sbjct: 174 ALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSAL-KQQEMVDTFLYLAKVYVSLD 232
Query: 330 QPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
QP+ AL + + G + +YE N A + Y
Sbjct: 233 QPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYY 275
Score = 31.6 bits (70), Expect = 5.4
Identities = 58/260 (22%), Positives = 103/260 (39%), Gaps = 28/260 (10%)
Query: 22 MAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLI 81
+A+ S + +++L + + G + L G R++E+ + A Y+ ++
Sbjct: 224 LAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEE----MNNMSSAAEYYKEVL 279
Query: 82 LKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYS--LQADYWKNAAFLYGLGLVYFY 139
+ VE+ HF YS R+Y LQ + N LGL FY
Sbjct: 280 KQDNTHVEAIACIGSNHF------YSDQPEIALRFYRRLLQMGIY-NGQLFNNLGLCCFY 332
Query: 140 YNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTL 199
+ + +F+ L + + A ++ LG + D + + F+LAL++ N
Sbjct: 333 AQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN---- 388
Query: 200 SNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDK 259
++AE ++A L RK H E LLQT +++ + H N + DK
Sbjct: 389 NHAEAYNNLAVL--EMRKGH--VEQARALLQT-------ASSLAPHMYEPHFNFATISDK 437
Query: 260 ATKESYAIQYLQKSLEADPN 279
+ QKS A P+
Sbjct: 438 IGDLQRSYVAAQKSEAAFPD 457
>gi|38146012 tetratricopeptide repeat domain 8 isoform B [Homo
sapiens]
Length = 505
Score = 41.2 bits (95), Expect = 0.007
Identities = 21/90 (23%), Positives = 44/90 (48%)
Query: 283 SWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAV 342
++ +L + Y S+ + A ++Q +DK C I +Y++ N A + Y +
Sbjct: 250 TFLYLAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVL 309
Query: 343 QLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
+ D+ H A +G+ + +QP+ A++ Y
Sbjct: 310 KQDNTHVEAIACIGSNHFYSDQPEIALRFY 339
Score = 38.1 bits (87), Expect = 0.057
Identities = 21/103 (20%), Positives = 47/103 (45%), Gaps = 4/103 (3%)
Query: 273 SLEADPNSGQSWYF---LGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQN 329
+L + + + W++ +G+CY +G ++A ++ ++ K + DT+ + +Y +
Sbjct: 204 ALSTEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFKSAL-KQQEMVDTFLYLAKVYVSLD 262
Query: 330 QPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCY 372
QP+ AL + + G + +YE N A + Y
Sbjct: 263 QPVTALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYY 305
Score = 31.6 bits (70), Expect = 5.4
Identities = 58/260 (22%), Positives = 103/260 (39%), Gaps = 28/260 (10%)
Query: 22 MAEGKASRESEEESVSLTVEEREALGGMDSRLFGFVRLHEDGARTKTLLGKAVRCYESLI 81
+A+ S + +++L + + G + L G R++E+ + A Y+ ++
Sbjct: 254 LAKVYVSLDQPVTALNLFKQGLDKFPGEVTLLCGIARIYEE----MNNMSSAAEYYKEVL 309
Query: 82 LKAEGKVESDFFCQLGHFNLLLEDYSKALSAYQRYYS--LQADYWKNAAFLYGLGLVYFY 139
+ VE+ HF YS R+Y LQ + N LGL FY
Sbjct: 310 KQDNTHVEAIACIGSNHF------YSDQPEIALRFYRRLLQMGIY-NGQLFNNLGLCCFY 362
Query: 140 YNAFHWAIKAFQDVLYVDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTL 199
+ + +F+ L + + A ++ LG + D + + F+LAL++ N
Sbjct: 363 AQQYDMTLTSFERALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQCFRLALVNNN---- 418
Query: 200 SNAEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDK 259
++AE ++A L RK H E LLQT +++ + H N + DK
Sbjct: 419 NHAEAYNNLAVL--EMRKGH--VEQARALLQT-------ASSLAPHMYEPHFNFATISDK 467
Query: 260 ATKESYAIQYLQKSLEADPN 279
+ QKS A P+
Sbjct: 468 IGDLQRSYVAAQKSEAAFPD 487
>gi|151301154 mucin 6, gastric [Homo sapiens]
Length = 2439
Score = 41.2 bits (95), Expect = 0.007
Identities = 102/486 (20%), Positives = 169/486 (34%), Gaps = 68/486 (13%)
Query: 481 SLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSA--GCIPCGTS-KILGST 537
S P ++ P + + V+ + + P + S+ SA G IP T+ K GST
Sbjct: 1437 SHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGST 1496
Query: 538 DTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTD-----------LNSSTEEPWRKQLS 586
T + +G+ S + + T T H+HT + T P +
Sbjct: 1497 HTAPPITPTTSGT-SQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTR 1555
Query: 587 NSAQGLHKSQSS-------CLSGPNEEQPLFSTG--SAQYHQATSTGIKKANEHLTLPSN 637
+ + SS S P P STG +A + T+T ++ TLP++
Sbjct: 1556 TPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTH 1615
Query: 638 SVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPET------SRHTGDT----S 687
P + S HT + + + ++ P T S HT T +
Sbjct: 1616 VPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675
Query: 688 NGCADVKGLSN--------HVHQLI---ADAVSSPNHGDSPNLLIADNPQLSALLIGKAN 736
+G + N H H A+A S+ +PN P ++ G +
Sbjct: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQ 1735
Query: 737 GNVGTGTCDKVNNIHPAVHTKTDH--SVASSPSSAIS-------TATPSPKSTEQRSINS 787
T ++H HT + H V S+ +++I+ T TP +T S
Sbjct: 1736 SRSSFSTAKTSTSLHS--HTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRL 1793
Query: 788 VT--SLNSPHSGLHTVNGEG---LGKSQSSTKVDLPLASHRSTSQILPSMSVS-ICPSST 841
T + +SP +G ++ G Q++T P H + +PS S S + PS+
Sbjct: 1794 PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTH 1853
Query: 842 EVLKACRNPGKNGLSNSCILLDKCPPPRP-----PTSPYPPL-PKDKLNPPTPSIYLENK 895
V+ S + PPP T PP+ P +PS + K
Sbjct: 1854 TVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAK 1913
Query: 896 RDAFFP 901
P
Sbjct: 1914 TSTSLP 1919
Score = 40.4 bits (93), Expect = 0.012
Identities = 95/467 (20%), Positives = 163/467 (34%), Gaps = 68/467 (14%)
Query: 527 PCGTSKILGSTDTILLGSNC-IAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQL 585
P TS + ST T++ ++ +A S SN + P T T+P T L ++ +
Sbjct: 1449 PFSTSLVTPSTHTVITPTHAQMATSASNHSAP-----TGTIPPP-TTLKATGSTHTAPPI 1502
Query: 586 SNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDAD 645
+ + G ++ SS + T S + + T T + T P +
Sbjct: 1503 TPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTSTRTRTPVAHTN 1562
Query: 646 SHLSCHTATSGGQQGIMFTKESKP------SKNRSLVPETSRHTGDTSNGCADVKGLSNH 699
S S FT S P S + + + T L H
Sbjct: 1563 SATSSRPPPP-------FTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTH 1615
Query: 700 VHQLIADAVSSPNHG--DSPNLLIADNPQLSALLIG--------KANGNVGT-------- 741
V V+ H + +A + + ++ G KA G+ T
Sbjct: 1616 VPPFSTSLVTPSTHTVITPTHAQMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTT 1675
Query: 742 -GTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHT 800
GT +++++ A + + HS SS A +T+T + T + TS +P + T
Sbjct: 1676 SGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP-----NPTSTGTPPMTVTT 1730
Query: 801 VNGEGLGKSQSSTKVDLPLASHRSTS---QILPSMSVSICPSSTEVLKACRNPGKNGLSN 857
S S+ K L SH S++ ++ + + SI P+ T R P + S
Sbjct: 1731 SGTSQSRSSFSTAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTST--GTRTPVAHTTSA 1788
Query: 858 SCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPKNPVTVI 917
+ L P P T+ PP ++ P + +P P +P T
Sbjct: 1789 TSSRL-----PTPFTTHSPPTGTTPISSTGPVTATSFQTTTTYP-------TPSHPHTT- 1835
Query: 918 RGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQLLQPADENWDPTGT 964
L + FST + + + ++ TQ+ A + PTGT
Sbjct: 1836 ------LPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGT 1876
Score = 37.7 bits (86), Expect = 0.075
Identities = 86/392 (21%), Positives = 133/392 (33%), Gaps = 41/392 (10%)
Query: 468 RTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIP 527
RT H + T S LPT ++ P G T +SS + + +P
Sbjct: 1779 RTPVAHTTSATSSRLPTPFTTHSPPTGT-TPISSTGPVTATSFQTTTTYPTPSHPHTTLP 1837
Query: 528 C-----GTSKILGSTDTILLGSNCIAGSESN------GNVP-----YLQQNTHTLPHNHT 571
TS + ST T+++ ++ + ++ G +P +THT P
Sbjct: 1838 THVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGSTHTAPPMTP 1897
Query: 572 DLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEH 631
+ +++ P + ++ L SS + E P +T H TSTG + H
Sbjct: 1898 TTSGTSQSPSSFSTAKTSTSLPYHTSS--THHPEVTPTSTTNITPKH--TSTGTRTPVAH 1953
Query: 632 LTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCA 691
T S+S + + H+ +G + S + T H T
Sbjct: 1954 TTSASSS----RLPTPFTTHSPPTGSSPFSSTGPMTATSFQTTTTYPTPSHPQTT----- 2004
Query: 692 DVKGLSNHVHQLIADAVSSPNHGDSPNLLIADNPQL--SALLIGKANGNVGTGTCDKVN- 748
L HV V+ H ++I + Q+ SA + G V T K
Sbjct: 2005 ----LPTHVPPFSTSLVTPSTH----TVIITTHTQMATSASIHSTPTGTVPPPTTLKATG 2056
Query: 749 NIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGK 808
+ H A S S S+ STAT S S S + P S T L
Sbjct: 2057 STHTAPPMTVTTSGTSQTHSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSS 2116
Query: 809 SQSSTKVDLPLASHRSTSQILPSMSVSICPSS 840
+ + L+S S S PS S PSS
Sbjct: 2117 ATTPVSTTNQLSSSFSPSPSAPSTVSSYVPSS 2148
Score = 37.4 bits (85), Expect = 0.098
Identities = 118/553 (21%), Positives = 183/553 (33%), Gaps = 90/553 (16%)
Query: 461 HKEVAQVRTTGIH-NGAITDSSLP---TNSVSNRQP------HGALTRVSSVSQPGVRPA 510
H EV TT I N T + P TNS ++ +P H T S S G A
Sbjct: 1534 HPEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTA 1593
Query: 511 CVEKLLSS--------GAFSAGCIPCGTSKILGSTDTILLGSNC-IAGSESNGNVPYLQQ 561
K ++ P TS + ST T++ ++ +A S S ++P
Sbjct: 1594 TSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASIHSMP---- 1649
Query: 562 NTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQAT 621
T T+P T L ++ ++ + G ++ SS + T S + +AT
Sbjct: 1650 -TGTIPPP-TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEAT 1707
Query: 622 STGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSR 681
ST +N P + TSG Q +K S + ++
Sbjct: 1708 STST----------TNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757
Query: 682 HTGDTSNGCADVKGLSNHVHQLIADAVSSPNHGDS---PNLLIADNPQLSALLIGKANGN 738
H TS + NH V+ S P +P I + G
Sbjct: 1758 HPEVTSTSTTSIT--PNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPIS-STGP 1814
Query: 739 VGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPS------PKSTEQRSINSVTSL- 791
V T T + +P PS + S TPS P T+ + S+ S+
Sbjct: 1815 V-TATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMP 1873
Query: 792 -------------NSPHSG---LHTVNGEGLGKSQSST-KVDLPLASHRSTS---QILPS 831
S H+ T +G S ST K L H S++ ++ P+
Sbjct: 1874 TGTIPPPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVTPT 1933
Query: 832 MSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPTSPYPPLPKDKLNPPTPSIY 891
+ +I P T R P + S S L P P T+ PP + P
Sbjct: 1934 STTNITPKHTST--GTRTPVAHTTSASSSRL-----PTPFTTHSPPTGSSPFSSTGPMTA 1986
Query: 892 LENKRDAFFPPLHQFCTNPKNPVTVIRGLAGALKLDLGLFSTKTLVEANNEHMVEVRTQL 951
+ +P P +P T L + FST + + + ++ TQ+
Sbjct: 1987 TSFQTTTTYP-------TPSHPQTT-------LPTHVPPFSTSLVTPSTHTVIITTHTQM 2032
Query: 952 LQPADENWDPTGT 964
A + PTGT
Sbjct: 2033 ATSASIHSTPTGT 2045
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 40.8 bits (94), Expect = 0.009
Identities = 63/282 (22%), Positives = 101/282 (35%), Gaps = 29/282 (10%)
Query: 543 GSNCIAGSESNGNVPYLQQNTHTLPHNH-----TDLNSSTEEPWRKQLSNSAQGLHKSQS 597
GS +S G+ ++++ + NH + P ++ G H + S
Sbjct: 294 GSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHG-HSADS 352
Query: 598 SCLSGPN--EEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATS 655
S SG E T S+ +S G + + H Q ADS S H+AT
Sbjct: 353 SRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGH---------QQSADS--SRHSATG 401
Query: 656 GGQQGIMFTKESKPSKNRSLVPETSRHT--GDTSNGCADVK-GLSNHVHQLIADAVSSPN 712
GQ + + S ++ H+ DT + K GL HQ S
Sbjct: 402 RGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGER 461
Query: 713 HGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAI 770
G S + L ++ + Q + A+G GT T + + H + HS + I
Sbjct: 462 SGRSGSSLYQVSTHEQPDS-----AHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTI 516
Query: 771 STATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
S + Q S + + S HSG H + G+S +S
Sbjct: 517 RGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDAS 558
Score = 39.3 bits (90), Expect = 0.026
Identities = 66/308 (21%), Positives = 108/308 (35%), Gaps = 29/308 (9%)
Query: 517 SSGAFSAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNH-----T 571
SS A S+G G + G + GS+ S+S G+ ++ + + NH
Sbjct: 2538 SSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQE 2597
Query: 572 DLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQA--TSTGIKKAN 629
L + P Q + G H + SS SG Q +A H+ +S G + +
Sbjct: 2598 QLRDGSRHPRSHQEDRAGHG-HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGS 2656
Query: 630 EHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNG 689
H Q ADS S H+ GQ + S + H+ D+
Sbjct: 2657 HH---------QQSADS--SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQ 2705
Query: 690 CADVKGLSN---HVHQLIADAVSSPNHGDSPNLL--IADNPQLSALLIGKANGNVGTGTC 744
G + HQ A S G S + L ++ + Q + ++G G T
Sbjct: 2706 SVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSES-----SHGWTGPSTR 2760
Query: 745 DKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGE 804
+ + H + HS + I S + Q + + +S HSG H +
Sbjct: 2761 GRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTT 2820
Query: 805 GLGKSQSS 812
G+S +S
Sbjct: 2821 SQGRSDAS 2828
Score = 37.4 bits (85), Expect = 0.098
Identities = 62/281 (22%), Positives = 102/281 (36%), Gaps = 27/281 (9%)
Query: 543 GSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSG 602
GS+ S+S G+ ++ + + NH + S +E R S + H+ ++ G
Sbjct: 2240 GSSVSQDSDSEGHSEDSERRSGSASRNH---HGSAQEQSRDG-SRHPRSHHEDRAG--HG 2293
Query: 603 PNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSN------SVPQGDADSHLSCHTATSG 656
+ E S S +H S+G + A+ H S+ S Q ADS S H+
Sbjct: 2294 HSAES---SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS--SRHSGIGH 2348
Query: 657 GQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSN---HVHQLIADAVSSPNH 713
GQ + S ++ H+ D+ G + HQ S+
Sbjct: 2349 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRS 2408
Query: 714 GDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIS 771
G S + L ++ + Q + A+G GT T + + H + HS + I
Sbjct: 2409 GRSGSFLYQVSTHEQSES-----AHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIH 2463
Query: 772 TATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
S Q S S HSG H + G+S +S
Sbjct: 2464 GHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDAS 2504
Score = 37.0 bits (84), Expect = 0.13
Identities = 57/282 (20%), Positives = 99/282 (35%), Gaps = 29/282 (10%)
Query: 543 GSNCIAGSESNGNVPYLQQNTHTLPHNHT-----DLNSSTEEPWRKQLSNSAQGLHKSQS 597
GS+ S+S G+ ++ + + NH + P + G H ++S
Sbjct: 3536 GSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHG-HSAES 3594
Query: 598 SCLSGPNEEQPLFSTGSAQYHQA--TSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATS 655
S SG + + +A H+ +S G + + H Q ADS S H+
Sbjct: 3595 SRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHH---------QQSADS--SRHSGIG 3643
Query: 656 GGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSN---HVHQLIADAVSSPN 712
GQ + S ++ H+ D+ G + HQ S+
Sbjct: 3644 HGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGR 3703
Query: 713 HGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAI 770
G S + L ++ + Q + A+G G T + + H + HS + I
Sbjct: 3704 SGRSGSFLYQVSTHEQSES-----AHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTI 3758
Query: 771 STATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
S + Q S + + S HSG H + G+S +S
Sbjct: 3759 RGHPGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDAS 3800
Score = 36.2 bits (82), Expect = 0.22
Identities = 61/290 (21%), Positives = 101/290 (34%), Gaps = 29/290 (10%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNH-----TDLNSSTEEPWRKQLSNSA 589
GS + GS+ S+S G+ ++ + + NH L + P Q +
Sbjct: 2880 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAG 2939
Query: 590 QGLHKSQSSCLSGPNEEQPLFSTGSAQYHQA--TSTGIKKANEHLTLPSNSVPQGDADSH 647
G H + SS SG Q +A H+ +S G + + H Q ADS
Sbjct: 2940 HG-HSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHH---------QQSADS- 2988
Query: 648 LSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSN---HVHQLI 704
S H+ GQ + S + H+ D+ G + HQ
Sbjct: 2989 -SRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQES 3047
Query: 705 ADAVSSPNHGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSV 762
A S G S + L ++ + Q + ++G G T + + H + HS
Sbjct: 3048 ARGRSGETSGHSGSFLYQVSTHEQSES-----SHGWTGPSTRGRQGSRHEQAQDSSRHSA 3102
Query: 763 ASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
+ I S + Q + + +S HSG H + G+S +S
Sbjct: 3103 SQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDAS 3152
Score = 34.7 bits (78), Expect = 0.64
Identities = 65/299 (21%), Positives = 108/299 (36%), Gaps = 35/299 (11%)
Query: 529 GTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHT-----DLNSSTEEPWRK 583
G + GS + GS+ S+S G+ ++ + + NH + P
Sbjct: 929 GQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH 988
Query: 584 QLSNSAQGLHKSQSSCLSG-PNEEQPLFSTGSAQYHQATST-GIKKANEHLTLPSNS--- 638
+ G H + SS SG P+ E ++ + QA S+ G + + H +S
Sbjct: 989 HEDRAGHG-HSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHS 1047
Query: 639 -VPQGDADSHL--SCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKG 695
+P+ A S + S H +SG Q +S+ S S H D G
Sbjct: 1048 GIPRRQASSAVRDSGHWGSSGSQ-----ASDSEGHSEESDTQSVSGHGQD---------G 1093
Query: 696 LSNHVHQLIADAVSSPNHGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPA 753
HQ A S G S + + ++ + Q + A+G T T + + H
Sbjct: 1094 PHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSES-----AHGRTRTSTGRRQGSHHEQ 1148
Query: 754 VHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
+ HS + I S + Q S + + S HSG H + G+S +S
Sbjct: 1149 ARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDAS 1207
Score = 34.3 bits (77), Expect = 0.83
Identities = 62/306 (20%), Positives = 104/306 (33%), Gaps = 24/306 (7%)
Query: 517 SSGAFSAGCIPCGTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNH-----T 571
SS A S+ G + G + GS+ S+S G+ ++ + + NH
Sbjct: 592 SSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQE 651
Query: 572 DLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQA--TSTGIKKAN 629
+ P + G H + SS SG Q S +A H+ +S G + +
Sbjct: 652 QSRDGSRHPRSHHEDRAGHG-HSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGS 710
Query: 630 EHLTLPSNSVPQGDADSHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNG 689
H ++S S H+ T GQ + S ++ H+ D+
Sbjct: 711 RHQLQSADS----------SRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQ 760
Query: 690 CADVKGLSNH---VHQLIADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDK 746
G + H HQ A S S + L + + ++G G T +
Sbjct: 761 SVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQS---ESSHGWTGPSTGVR 817
Query: 747 VNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGL 806
+ H + HS + I S + Q S + + S HSG H +
Sbjct: 818 QGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQ 877
Query: 807 GKSQSS 812
G+S +S
Sbjct: 878 GRSDAS 883
Score = 32.3 bits (72), Expect = 3.2
Identities = 55/277 (19%), Positives = 93/277 (33%), Gaps = 28/277 (10%)
Query: 572 DLNSSTEEPWRKQLSNSAQGLHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEH 631
D +S ++LS SA H S S P F H ++ +++ H
Sbjct: 1273 DSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQSGTH 1332
Query: 632 LTLPSN---------SVPQGDADSHLSCH--TATSGGQQGIMFTKESKPSKNR------- 673
T S+ + H S H +A S GI + S ++
Sbjct: 1333 HTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQASSAVRDSGHRGSSG 1392
Query: 674 SLVPETSRHTGDTSNGCADVKGLSN---HVHQLIADAVSSPNHGDSPNLL--IADNPQLS 728
S V + H+ D+ G + H+ A S + G S + L ++ + Q
Sbjct: 1393 SQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSE 1452
Query: 729 ALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAISTATPSPKSTEQRSINSV 788
+ +G T + + H + HS + I S + Q S +
Sbjct: 1453 S-----THGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQ 1507
Query: 789 TSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRST 825
+ S HSG H + G+S +S P ++ R T
Sbjct: 1508 SVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQT 1544
Score = 31.6 bits (70), Expect = 5.4
Identities = 59/282 (20%), Positives = 98/282 (34%), Gaps = 27/282 (9%)
Query: 529 GTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNH-----TDLNSSTEEPWRK 583
G + GS + GS+ +S G+ ++ + + NH + P
Sbjct: 1577 GQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH 1636
Query: 584 QLSNSAQGLHKSQSSCLSGPNEEQPLFS--TGSAQYHQATSTGIKKANEHLTLPSNSVPQ 641
Q ++ G H ++SS SG + S+Q +S G + + H +S
Sbjct: 1637 QEDRASHG-HSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDS 1695
Query: 642 GDADSHLSCHTATSG--GQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNH 699
G S SG G G ++ S+ S E S +++G A G
Sbjct: 1696 GTGRRQDSSVVGDSGNRGSSG----SQASDSEGHS---EESDTQSVSAHGQA---GPHQQ 1745
Query: 700 VHQLIADAVSSPNHGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTK 757
HQ S G S + L ++ + Q + A+G G T + + H
Sbjct: 1746 SHQESTRGQSGERSGRSGSFLYQVSTHEQSES-----AHGRTGPSTGGRQRSRHEQARDS 1800
Query: 758 TDHSVASSPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLH 799
+ HS + I S + Q S + +S HSG H
Sbjct: 1801 SRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSH 1842
Score = 31.6 bits (70), Expect = 5.4
Identities = 53/223 (23%), Positives = 79/223 (35%), Gaps = 38/223 (17%)
Query: 611 STGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCH--TATSGGQQGIMFTKESK 668
S S H TS+G + A+ H S+ + H S H +A S GI
Sbjct: 3271 SRQSGTRHAETSSGGQAASSHEQARSSP-----GERHGSRHQQSADSSRHSGI------- 3318
Query: 669 PSKNRSLVPETSRHTGDTSNGCADVKG---------LSNH--------VHQLIADAVSSP 711
P S SRH G + + +D +G +S H HQ A S
Sbjct: 3319 PRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGG 3378
Query: 712 NHGDSPNLL--IADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSA 769
G S + L ++ + Q + A+G T T + + H + HS +
Sbjct: 3379 RSGRSGSFLYQVSTHEQSES-----AHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDT 3433
Query: 770 ISTATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSS 812
I S + Q S + S HSG H + G+S +S
Sbjct: 3434 IRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDAS 3476
>gi|22749211 transmembrane and tetratricopeptide repeat containing 2
[Homo sapiens]
Length = 836
Score = 40.4 bits (93), Expect = 0.012
Identities = 23/98 (23%), Positives = 50/98 (51%)
Query: 279 NSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAY 338
N ++W LG S K+ +A +YR ++ AD ++G+L Q+ ++ +AL Y
Sbjct: 491 NPAKAWGNLGNVLKSQSKISEAESAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYY 550
Query: 339 ICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNAA 376
A+ A+A+++ G + + + ++A + +L +
Sbjct: 551 KLAIGSRPTLASAYLNTGIILMNQGRTEEARRTFLKCS 588
Score = 35.8 bits (81), Expect = 0.29
Identities = 65/320 (20%), Positives = 124/320 (38%), Gaps = 44/320 (13%)
Query: 97 GHFNLLLEDYSKALSAYQRYYSLQADYWKN--AAFLYGLGLVYFYYNAFHWAIKAFQDVL 154
G+ +L+ SK A Y + A Y+++ A LY LGL+ + F A+ ++ +
Sbjct: 497 GNLGNVLKSQSKISEAESAYRN--ALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAI 554
Query: 155 YVDPSFCRAKEIHLRLGLMF----KVNTDYKSSLKHFQLA---LIDCNPCTLSNAEIQFH 207
P+ A +L G++ + ++ LK ++ L D + S ++
Sbjct: 555 GSRPTLASA---YLNTGIILMNQGRTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYN 611
Query: 208 IAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQL---GWM---------HHNMDL 255
+ LY Q Y A Y++ +Q +P Q L + +M H M+
Sbjct: 612 LGKLYHEQGHYEEALSVYKEAIQ--KMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMES 669
Query: 256 VGDKAT----------------KESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQD 299
+ K ++S A + K++E DP G + G+ ++ +
Sbjct: 670 LRSKTDHIPAHLTYGKLLALTGRKSEAEKLFLKAIELDPTKGNCYMHYGQFLLEEARLIE 729
Query: 300 AFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLY 359
A +++ + D + + +Q + A + Y A +L + AA M+LG +
Sbjct: 730 AAEMAKKAAELDSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNYPAALMNLGAIL 789
Query: 360 ESCNQPQDAIKCYLNAARSK 379
+ Q A YL A + K
Sbjct: 790 HLNGRLQKAEANYLRALQLK 809
>gi|239754668 PREDICTED: mucin 12 [Homo sapiens]
Length = 1952
Score = 40.0 bits (92), Expect = 0.015
Identities = 66/302 (21%), Positives = 102/302 (33%), Gaps = 36/302 (11%)
Query: 535 GSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLS-NSAQGLH 593
GST T+ + A S + THT+ + ++ EEP S S H
Sbjct: 1227 GSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSIATTH 1286
Query: 594 KSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNS-------VPQGDADS 646
+SS SG +EE +A + + GI H T + G ++
Sbjct: 1287 FPESSTTSGRSEES------TASHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMET 1340
Query: 647 HLSCHTATSG--GQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLI 704
L+ T G + I+++ P + S TS +S L
Sbjct: 1341 TLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTS-------------SSISGEPTSLY 1387
Query: 705 ADAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVAS 764
+ A S+ + + Q S K T + + A T HS
Sbjct: 1388 SQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHS--- 1444
Query: 765 SPSSAISTATPSPKSTEQRSINSVTSLNSPHSGLHTV----NGEGLGKSQSSTKVDLPLA 820
P SA+ST +P+ + S S T +SP S T N + QS+ D P
Sbjct: 1445 QPGSALSTVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQQSTPFPDSPGF 1504
Query: 821 SH 822
+H
Sbjct: 1505 TH 1506
Score = 36.6 bits (83), Expect = 0.17
Identities = 79/382 (20%), Positives = 139/382 (36%), Gaps = 46/382 (12%)
Query: 477 ITDSSLPTNSVSNRQPHGALTRVSSVSQPGVRPACVEKLLSSGAFSAGCIPCGTSKILGS 536
+ ++S+P +S S R PH L+ S ++ G S+ A P TS +
Sbjct: 665 LLEASMPVHS-STRSPHTTLSPAGSTTRQGESTTFHSWPSSNDTRPAP--PTTTSAFVEP 721
Query: 537 TDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSST-----EEPWRKQLSNSAQG 591
+ T S+G+ ++P H S+T E S Q
Sbjct: 722 STT------------SHGS-------PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQT 762
Query: 592 LHKSQSSCLSGPNEEQPLFSTGSAQYHQATSTGIKKANEHLTLPSNSVPQGDADSHLSCH 651
+H +S SG EE S S + +++ A +S P A +H
Sbjct: 763 MHFPESDTTSGRGEESTT-SHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDS 821
Query: 652 TATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSP 711
+ TSG + + + S+ + ++P +R T G + +S+ + A S+
Sbjct: 822 STTSGRSEESIASHSSQDATGTIVLP--ARSTNSVLLGESTTSPISSGSMETTALPGSTT 879
Query: 712 NHGDSP-NLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAI 770
G S + +P+ A + A+ +G ++ H S P S
Sbjct: 880 TPGLSERSTTFHSSPRSPATTLSPAS-TTSSGVSEESTTSH------------SRPGSTH 926
Query: 771 STATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILP 830
+TA P +T S +S TS +SP S T+ P++S + + LP
Sbjct: 927 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTXLVGEPTTSPISSGSTETTALP 986
Query: 831 --SMSVSICPSSTEVLKACRNP 850
+ + + ST + R+P
Sbjct: 987 GSTTTAGLSEKSTTFYSSPRSP 1008
Score = 35.8 bits (81), Expect = 0.29
Identities = 98/461 (21%), Positives = 154/461 (33%), Gaps = 65/461 (14%)
Query: 446 LEQLESQFVLMQQMRHKEVAQVRTTGIHNGAITDSSLPTNSVSNRQPHGALTRVSSVSQP 505
L + + F + + ++ RTT + +++ S T S S P + S + P
Sbjct: 197 LSEKSTTFYSSPRSPDRTLSPARTT---SSGVSEKS--TTSHSRPGPTHTIAFPDSTTMP 251
Query: 506 GVRPACVEKLLSSGAFSAGCIPCGTSKIL--GSTDTILLGSNCIAGSESNG--NVPYLQQ 561
GV S + ++ IP T L G+T LG S G L
Sbjct: 252 GV---------SQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYTKTTRLPD 302
Query: 562 NTHT--LPHNHTDLNSSTEEPWRKQLSNSAQGLHKSQSSCLSG----------PNEEQPL 609
NT T L T ++SST P LS ++ H+ + + P+
Sbjct: 303 NTTTSGLLEASTPVHSSTGSP-HTTLSPASSTTHEGEPTTFQSWPSSKDTSPAPSGTTSA 361
Query: 610 FSTGSAQYHQ-----------ATSTGIKKANEHLTLPSNSVPQGDADSHLSCHTATSGGQ 658
F S YH A+ST + + E + P +S P A + +ATSG
Sbjct: 362 FVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE--STPVHSSPVATATTPPPARSATSGHV 419
Query: 659 QGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIADAVSSPNH----- 713
+ S S PE+S +G + A G + H ++ H
Sbjct: 420 EESTAYHRSPGSTQTMHFPESSTTSGHSEES-ATFHGSTTHTKSSTPSTTAALAHTSYHS 478
Query: 714 --GDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASSPSSAIS 771
G + D+ +S G K ++ P T S+PS +
Sbjct: 479 SLGSTETTHFRDSSTIS-----------GRSEESKASHSSPDAMATTVLPAGSTPSVLVG 527
Query: 772 TATPSPKSTEQRSINSVTSLNSPHSGLHTVNGEGLGKSQSSTKVDLPLASHRSTSQILPS 831
+TPSP S+ ++ ++ GL + +S LP AS S+ S
Sbjct: 528 DSTPSPISSGSMETTALPG-STTKPGLSEKSTTFYSSPRSPDTTHLP-ASMTSSGVSEES 585
Query: 832 MSVSICPSSTEVLKACRNPGKNGLSNSCILLDKCPPPRPPT 872
+ P ST + GLS P P T
Sbjct: 586 TTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTT 626
Score = 35.0 bits (79), Expect = 0.49
Identities = 78/325 (24%), Positives = 132/325 (40%), Gaps = 41/325 (12%)
Query: 529 GTSKILGSTDTILLGSNCIAGSESNGNVPYLQQNTHTLPHNHTDLNSSTEEPWRKQLSNS 588
G S+I GST +G N + S + + P+ + + + + T + ST + L +S
Sbjct: 81 GFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGV--SVTFITGSTAT--KHFLDSS 136
Query: 589 AQGLHKSQSSCL-SGPNEEQPLFSTGSAQY--HQATSTGIKKANEHLTLPSNSVPQGDAD 645
H +S+ SGP +TG+ + H ATS + E T P S
Sbjct: 137 TNSGHSEESTVSHSGPG------ATGTTLFPSHSATSVFV---GEPKTSPITSASM--ET 185
Query: 646 SHLSCHTATSGGQQGIMFTKESKPSKNRSLVPETSRHTGDTSNGCADVKGLSNHVHQLIA 705
+ L T T+G + S S +R+L P + TS+G ++ K ++H
Sbjct: 186 TALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPART-----TSSGVSE-KSTTSHSRPGPT 239
Query: 706 DAVSSPNHGDSPNLLIADNPQLSALLIGKANGNVGTGTCDKVNNIHPAVHTKTDHSVASS 765
++ P+ P ++ S + G + + GT +++ P + T H SS
Sbjct: 240 HTIAFPDSTTMPG--VSQESTASHSIPGSTDTTLSPGTTTP-SSLGP--ESTTFH---SS 291
Query: 766 PSSAISTATPSPKSTE---QRSINSVTSLNSPHSGLH-----TVNGEGLG-KSQSSTKVD 816
P +T P +T + S +S SPH+ L T GE +S S+K
Sbjct: 292 PGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPASSTTHEGEPTTFQSWPSSKDT 351
Query: 817 LPLASHRSTSQILPSMSVSICPSST 841
P S +++ + S + PSST
Sbjct: 352 SPAPSGTTSAFVKLSTTYHSSPSST 376
>gi|83415184 transmembrane and tetratricopeptide repeat containing 1
[Homo sapiens]
Length = 774
Score = 39.7 bits (91), Expect = 0.020
Identities = 29/114 (25%), Positives = 49/114 (42%)
Query: 262 KESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSI 321
K+ AI L+ S++ P ++ L + + ++A Y+ I S+D +
Sbjct: 455 KKEEAITLLKDSIKYGPEFADAYSSLASLLAEQERFKEAEEIYQTGIKNCPDSSDLHNNY 514
Query: 322 GVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDAIKCYLNA 375
GV P A+ Y A++L H A ++LG LY S + A + Y A
Sbjct: 515 GVFLVDTGLPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRA 568
Score = 38.9 bits (89), Expect = 0.034
Identities = 49/213 (23%), Positives = 91/213 (42%), Gaps = 18/213 (8%)
Query: 96 LGHFNLLLEDYSKALSAYQRYYSLQADYWKNAAFLYGLGLVYFYYNAFHWAIKAFQDVLY 155
LG L + S A Y+R +LQ + A L LG +Y+ + A++ +Q+
Sbjct: 548 LGRLYRSLGENSMAEEWYKR--ALQVAH--KAEILSPLGALYYNTGRYEEALQIYQEAAA 603
Query: 156 VDPSFCRAKEIHLRLGLMFKVNTDYKSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQ 215
+ PS +E+ L L + V K + K + + C E ++ +Y Q
Sbjct: 604 LQPS---QRELRLALAQVLAVMGQTKEAEKMTNHIVSEETGC----LECYRLLSAIYSKQ 656
Query: 216 RKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLE 275
+ A +A ++ LQ + +V + + G +L+ DKA ESY + +++
Sbjct: 657 ENHDKALDAIDKALQLKPKDPKVISELFFTKGNQLREQNLL-DKAF-ESYRV-----AVQ 709
Query: 276 ADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSI 308
+P+ Q+W +G GK A Y +++
Sbjct: 710 LNPDQAQAWMNMGGIQHIKGKYVSARAYYERAL 742
Score = 37.7 bits (86), Expect = 0.075
Identities = 46/210 (21%), Positives = 86/210 (40%), Gaps = 28/210 (13%)
Query: 202 AEIQFHIAHLYETQRKYHSAKEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKAT 261
A+ +A L Q ++ A+E Y+ ++ N P +H+N +
Sbjct: 474 ADAYSSLASLLAEQERFKEAEEIYQTGIK--NCPDSSD---------LHNNYGVFLVDTG 522
Query: 262 KESYAIQYLQKSLEADPNSGQSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSI 321
A+ + Q++++ P+ + LGR Y S+G+ A Y++++ + A+ +
Sbjct: 523 LPEKAVAHYQQAIKLSPSHHVAMVNLGRLYRSLGENSMAEEWYKRALQVAH-KAEILSPL 581
Query: 322 GVLYQQQNQPMDALQAYICAVQLDHGHAAAWMDLGTLYESCNQPQDA------------- 368
G LY + +ALQ Y A L + L + Q ++A
Sbjct: 582 GALYYNTGRYEEALQIYQEAAALQPSQRELRLALAQVLAVMGQTKEAEKMTNHIVSEETG 641
Query: 369 -IKCY--LNAARSKRCSNTSTLAARIKFLQ 395
++CY L+A SK+ ++ L A K LQ
Sbjct: 642 CLECYRLLSAIYSKQENHDKALDAIDKALQ 671
Score = 35.0 bits (79), Expect = 0.49
Identities = 46/233 (19%), Positives = 94/233 (40%), Gaps = 56/233 (24%)
Query: 163 AKEIHLRLGLMFKVNTDY-KSSLKHFQLALIDCNPCTLSNAEIQFHIAHLYETQRKYHSA 221
+ ++H G+ F V+T + ++ H+Q A I +P S+ ++ LY + + A
Sbjct: 507 SSDLHNNYGV-FLVDTGLPEKAVAHYQQA-IKLSP---SHHVAMVNLGRLYRSLGENSMA 561
Query: 222 KEAYEQLLQTENLPAQVKATVLQQLGWMHHNMDLVGDKATKESYAIQYLQKSLEADPNSG 281
+E Y++ LQ + KA +L LG +++N + A+Q Q++ P+
Sbjct: 562 EEWYKRALQVAH-----KAEILSPLGALYYNTG-------RYEEALQIYQEAAALQPSQR 609
Query: 282 QSWYFLGRCYSSIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQN------------ 329
+ L + + +G+ ++A + + + + + +Y +Q
Sbjct: 610 ELRLALAQVLAVMGQTKEAEKMTNHIVSEETGCLECYRLLSAIYSKQENHDKALDAIDKA 669
Query: 330 ---QPMD-----------------------ALQAYICAVQLDHGHAAAWMDLG 356
+P D A ++Y AVQL+ A AWM++G
Sbjct: 670 LQLKPKDPKVISELFFTKGNQLREQNLLDKAFESYRVAVQLNPDQAQAWMNMG 722
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.392
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,968,015
Number of Sequences: 37866
Number of extensions: 2636463
Number of successful extensions: 14247
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 56
Number of HSP's successfully gapped in prelim test: 161
Number of HSP's that attempted gapping in prelim test: 12909
Number of HSP's gapped (non-prelim): 1174
length of query: 1347
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1233
effective length of database: 13,930,794
effective search space: 17176669002
effective search space used: 17176669002
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.