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Search of human proteins with 32967314
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
(539 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo sapi... 1128 0.0
gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo sapi... 1109 0.0
gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo sap... 737 0.0
gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo sap... 737 0.0
gi|145312251 EPH receptor A6 isoform a [Homo sapiens] 728 0.0
gi|4758280 ephrin receptor EphA4 [Homo sapiens] 683 0.0
gi|4758282 ephrin receptor EphA7 [Homo sapiens] 675 0.0
gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo sapi... 662 0.0
gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo sap... 569 e-162
gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo sapi... 569 e-162
gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens] 556 e-158
gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo sapi... 554 e-158
gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens] 535 e-152
gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens] 521 e-148
gi|32967311 ephrin receptor EphA2 [Homo sapiens] 468 e-132
gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens] 404 e-112
gi|32528301 EPH receptor B4 precursor [Homo sapiens] 384 e-106
gi|221316650 ephrin receptor EphA1 [Homo sapiens] 383 e-106
gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens] 324 1e-88
gi|222537743 protein tyrosine phosphatase, receptor type, Q [Hom... 73 8e-13
gi|104487002 protein tyrosine phosphatase, receptor type, D isof... 65 2e-10
gi|4506309 protein tyrosine phosphatase, receptor type, D isofor... 65 2e-10
gi|18860890 protein tyrosine phosphatase, receptor type, D isofo... 65 2e-10
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 65 2e-10
gi|18860894 protein tyrosine phosphatase, receptor type, D isofo... 65 2e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 63 6e-10
gi|110349717 titin isoform novex-2 [Homo sapiens] 63 6e-10
gi|110349713 titin isoform novex-1 [Homo sapiens] 63 6e-10
gi|110349715 titin isoform N2-B [Homo sapiens] 63 6e-10
gi|157311649 neogenin homolog 1 [Homo sapiens] 63 8e-10
>gi|32967314 ephrin receptor EphA3 isoform b precursor [Homo
sapiens]
Length = 539
Score = 1128 bits (2917), Expect = 0.0
Identities = 539/539 (100%), Positives = 539/539 (100%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
Sbjct: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
Query: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
Sbjct: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
Query: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
Sbjct: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
Query: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
Sbjct: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
Sbjct: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
Query: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
Sbjct: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
Query: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
Sbjct: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
Query: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYYFNAV 539
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYYFNAV
Sbjct: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYYFNAV 539
>gi|21361241 ephrin receptor EphA3 isoform a precursor [Homo
sapiens]
Length = 983
Score = 1109 bits (2869), Expect = 0.0
Identities = 531/531 (100%), Positives = 531/531 (100%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE
Sbjct: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
Query: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF
Sbjct: 61 HYTPIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETF 120
Query: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY
Sbjct: 121 NLYYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP
Sbjct: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPP 240
Query: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG
Sbjct: 241 RMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDG 300
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN
Sbjct: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFN 360
Query: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS
Sbjct: 361 IICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSS 420
Query: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ
Sbjct: 421 PPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQ 480
Query: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD
Sbjct: 481 ETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
>gi|221625422 ephrin receptor EphA5 isoform b precursor [Homo
sapiens]
Length = 1015
Score = 737 bits (1902), Expect = 0.0
Identities = 339/522 (64%), Positives = 423/522 (81%), Gaps = 5/522 (0%)
Query: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
Query: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
Query: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
Query: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
Query: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
Query: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
Query: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
Query: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P
Sbjct: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP 561
>gi|221625401 ephrin receptor EphA5 isoform a precursor [Homo
sapiens]
Length = 1037
Score = 737 bits (1902), Expect = 0.0
Identities = 339/522 (64%), Positives = 423/522 (81%), Gaps = 5/522 (0%)
Query: 10 LLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQ 69
LL C+ L + L+ PSNEVNLLDS+T+ G+LGWI++P +GWEEI VDE+Y PI TYQ
Sbjct: 44 LLLCAALRT---LLASPSNEVNLLDSRTVMGDLGWIAFPKNGWEEIGEVDENYAPIHTYQ 100
Query: 70 VCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDD 129
VC VM+ +QNNWL T+W+ A +I++ELKFTLRDCNS+P LGTCKETFN+YY ESDD
Sbjct: 101 VCKVMEQNQNNWLLTSWISNEGASRIFIELKFTLRDCNSLPGGLGTCKETFNMYYFESDD 160
Query: 130 DHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGAC 189
+G +E+Q+ KIDTIAADESFT++DLGDR++KLNTE+R+VGP++KKGFYLAFQDVGAC
Sbjct: 161 QNGRNIKENQYIKIDTIAADESFTELDLGDRVMKLNTEVRDVGPLSKKGFYLAFQDVGAC 220
Query: 190 VALVSVRVYFKKCPFTVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEG 248
+ALVSVRVY+KKCP V++LA+FPDT+ DS L+EV GSCVN+S ++PP+M+CS EG
Sbjct: 221 IALVSVRVYYKKCPSVVRHLAVFPDTITGADSSQLLEVSGSCVNHSVTDEPPKMHCSAEG 280
Query: 249 EWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCEN 308
EWLVPIGKC C AGYEE+ CQ CRPGF+KA C KCPPHS T E+ S +C CE
Sbjct: 281 EWLVPIGKCMCKAGYEEKNGTCQVCRPGFFKASPHIQSCGKCPPHSYTHEEASTSCVCEK 340
Query: 309 NYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGW 368
+YFR + DPP+MACTRPPS+PRN ISN+NETSV L+W P DTGGRKDV++ I CKKC
Sbjct: 341 DYFRRESDPPTMACTRPPSAPRNAISNVNETSVFLEWIPPADTGGRKDVSYYIACKKCNS 400
Query: 369 NIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAV 428
+ CE C +VR+LPRQ GL NT+V + DLLAHTNYTFEI+AVNGVS+LS RQ+ +V
Sbjct: 401 HAGVCEECGGHVRYLPRQSGLKNTSVMMVDLLAHTNYTFEIEAVNGVSDLSPGARQYVSV 460
Query: 429 SITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR 488
++TTNQAAPSPV +KK + ++NSISLSWQEP+ PNGIIL+YE+KY+EK +QETSYTI++
Sbjct: 461 NVTTNQAAPSPVTNVKKGKIAKNSISLSWQEPDRPNGIILEYEIKYFEK-DQETSYTIIK 519
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
++ T +T LKP ++YVFQIRARTAAGYG SR+FEFET+P
Sbjct: 520 SKETTITAEGLKPASVYVFQIRARTAAGYGVFSRRFEFETTP 561
>gi|145312251 EPH receptor A6 isoform a [Homo sapiens]
Length = 1130
Score = 728 bits (1879), Expect = 0.0
Identities = 330/506 (65%), Positives = 414/506 (81%), Gaps = 1/506 (0%)
Query: 27 SNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNW 86
+N+V LLD+ T+ GELGW +YP +GW+ I+ +DEH PI TYQVCNVM+ +QNNWLRTNW
Sbjct: 126 NNQVVLLDTTTVLGELGWKTYPLNGWDAITEMDEHNRPIHTYQVCNVMEPNQNNWLRTNW 185
Query: 87 VPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTI 146
+ R++AQKIYVE+KFTLRDCNSIP VLGTCKETFNL+YMESD+ HG+KF+ +Q+TKIDTI
Sbjct: 186 ISRDAAQKIYVEMKFTLRDCNSIPWVLGTCKETFNLFYMESDESHGIKFKPNQYTKIDTI 245
Query: 147 AADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTV 206
AADESFTQMDLGDRILKLNTEIREVGP+ +KGFYLAFQD+GAC+ALVSVRV++KKCPFTV
Sbjct: 246 AADESFTQMDLGDRILKLNTEIREVGPIERKGFYLAFQDIGACIALVSVRVFYKKCPFTV 305
Query: 207 KNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEE 265
+NLAMFPDT+P +DS SLVEVRGSCV +++E D P++YC +G+WLVP+G+C C+ GYEE
Sbjct: 306 RNLAMFPDTIPRVDSSSLVEVRGSCVKSAEERDTPKLYCGADGDWLVPLGRCICSTGYEE 365
Query: 266 RGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP 325
C ACRPGFYKA GN KC+KCPPHS T + + C+CE YFRA+KDPPSMACTRP
Sbjct: 366 IEGSCHACRPGFYKAFAGNTKCSKCPPHSLTYMEATSVCQCEKGYFRAEKDPPSMACTRP 425
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
PS+PRNV+ NINET++IL+WS P DTGGRKD+T+++ICKKCG + QCE C +RF+PR
Sbjct: 426 PSAPRNVVFNINETALILEWSPPSDTGGRKDLTYSVICKKCGLDTSQCEDCGGGLRFIPR 485
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445
GL N +V V D ++H NYTFEI+A+NGVSELS P+ F A+++TT+Q APS + ++K
Sbjct: 486 HTGLINNSVIVLDFVSHVNYTFEIEAMNGVSELSFSPKPFTAITVTTDQDAPSLIGVVRK 545
Query: 446 DRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
D S+NSI+LSWQ P NG ILDYE+KYYEK+ ++ +Y+ R++ +V I+ LKP T Y
Sbjct: 546 DWASQNSIALSWQAPAFSNGAILDYEIKYYEKEHEQLTYSSTRSKAPSVIITGLKPATKY 605
Query: 506 VFQIRARTAAGYGTNSRKFEFETSPD 531
VF IR RTA GY S+KFEFET +
Sbjct: 606 VFHIRVRTATGYSGYSQKFEFETGDE 631
>gi|4758280 ephrin receptor EphA4 [Homo sapiens]
Length = 986
Score = 683 bits (1763), Expect = 0.0
Identities = 319/507 (62%), Positives = 399/507 (78%), Gaps = 3/507 (0%)
Query: 26 PSNEVNLLDSKTIQGELGWISYPSHG-WEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
P+NEV LLDS+++QGELGWI+ P G WEE+S +DE TPIRTYQVCNVM+ SQNNWLRT
Sbjct: 27 PANEVTLLDSRSVQGELGWIASPLEGGWEEVSIMDEKNTPIRTYQVCNVMEPSQNNWLRT 86
Query: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
+W+ R AQ++Y+E+KFTLRDCNS+P V+GTCKETFNLYY ESD+D RE+QF KID
Sbjct: 87 DWITREGAQRVYIEIKFTLRDCNSLPGVMGTCKETFNLYYYESDNDKERFIRENQFVKID 146
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESFTQ+D+GDRI+KLNTEIR+VGP++KKGFYLAFQDVGAC+ALVSVRV++KKCP
Sbjct: 147 TIAADESFTQVDIGDRIMKLNTEIRDVGPLSKKGFYLAFQDVGACIALVSVRVFYKKCPL 206
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263
TV+NLA FPDT+ D+ SLVEVRGSCVNNS+E+D P+MYC +GEWLVPIG C CNAG+
Sbjct: 207 TVRNLAQFPDTITGADTSSLVEVRGSCVNNSEEKDVPKMYCGADGEWLVPIGNCLCNAGH 266
Query: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
EER CQAC+ G+YKAL + CAKCPPHS + +G+ +C C+ +FRAD D SM CT
Sbjct: 267 EERSGECQACKIGYYKALSTDATCAKCPPHSYSVWEGATSCTCDRGFFRADNDAASMPCT 326
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG-WNIKQCEPCSPNVRF 382
RPPS+P N+ISN+NETSV L+WS P +TGGR+D+++N++CKKCG + +C PC V +
Sbjct: 327 RPPSAPLNLISNVNETSVNLEWSSPQNTGGRQDISYNVVCKKCGAGDPSKCRPCGSGVHY 386
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
P+Q GL T V++TDLLAHTNYTFEI AVNGVS+ + P Q +V++TTNQAAPS +
Sbjct: 387 TPQQNGLKTTKVSITDLLAHTNYTFEIWAVNGVSKYNPNPDQSVSVTVTTNQAAPSSIAL 446
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
++ +R S++L+W EP+ PNG+IL+YEVKYYEK + E SY I+R N I L P
Sbjct: 447 VQAKEVTRYSVALAWLEPDRPNGVILEYEVKYYEKDQNERSYRIVRTAARNTDIKGLNPL 506
Query: 503 TIYVFQIRARTAAGYGTNSRKFEFETS 529
T YVF +RARTAAGYG S E T+
Sbjct: 507 TSYVFHVRARTAAGYGDFSEPLEVTTN 533
>gi|4758282 ephrin receptor EphA7 [Homo sapiens]
Length = 998
Score = 675 bits (1741), Expect = 0.0
Identities = 312/507 (61%), Positives = 402/507 (79%), Gaps = 3/507 (0%)
Query: 25 QPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRT 84
Q + EV LLDSK Q EL WIS P +GWEEISG+DE+YTPIRTYQVC VM+ +QNNWLRT
Sbjct: 28 QAAKEVLLLDSKAQQTELEWISSPPNGWEEISGLDENYTPIRTYQVCQVMEPNQNNWLRT 87
Query: 85 NWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKID 144
NW+ + +AQ+I+VELKFTLRDCNS+P VLGTCKETFNLYY E+D D G RE+ + KID
Sbjct: 88 NWISKGNAQRIFVELKFTLRDCNSLPGVLGTCKETFNLYYYETDYDTGRNIRENLYVKID 147
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESFTQ DLG+R +KLNTE+RE+GP++KKGFYLAFQDVGAC+ALVSV+VY+KKC
Sbjct: 148 TIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWS 207
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEE--DPPRMYCSTEGEWLVPIGKCSCNA 261
++NLA+FPDTV + SLVEVRG+CV++++EE + PRM+CS EGEWLVPIGKC C A
Sbjct: 208 IIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKA 267
Query: 262 GYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
GY+++G C+ C GFYK+ +++C++CP HS + ++GS C CE+ Y+RA DPP +A
Sbjct: 268 GYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRAPSDPPYVA 327
Query: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
CTRPPS+P+N+I NIN+T+V L+WS P D GGR DVT+ I+CK+C W +C PC N+
Sbjct: 328 CTRPPSAPQNLIFNINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIG 387
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
++P+Q GL + VTV DLLAH NYTFE++AVNGVS+LS R FAAVSITT QAAPS V
Sbjct: 388 YMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVS 447
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+ K+R + S+ LSWQEPEHPNG+I +YE+KYYEK ++E +Y+ ++ + T+ +I++LKP
Sbjct: 448 GVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKP 507
Query: 502 DTIYVFQIRARTAAGYGTNSRKFEFET 528
T+YVFQIRA TAAGYG S + + T
Sbjct: 508 GTVYVFQIRAFTAAGYGNYSPRLDVAT 534
>gi|10140845 ephrin receptor EphA8 isoform 1 precursor [Homo
sapiens]
Length = 1005
Score = 662 bits (1707), Expect = 0.0
Identities = 305/501 (60%), Positives = 387/501 (77%), Gaps = 1/501 (0%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
Query: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
Query: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
Query: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
Query: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
Query: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQAAPS V+ I+++R
Sbjct: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQAAPSQVVVIRQER 450
Query: 448 TSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVF 507
+ S+SL WQEPE PNGIIL+YE+KYYEK ++ SY+ L+A T T+S LKP T YVF
Sbjct: 451 AGQTSVSLLWQEPEQPNGIILEYEIKYYEKDKEMQSYSTLKAVTTRATVSGLKPGTRYVF 510
Query: 508 QIRARTAAGYGTNSRKFEFET 528
Q+RART+AG G S+ E ET
Sbjct: 511 QVRARTSAGCGRFSQAMEVET 531
>gi|111118978 ephrin receptor EphB2 isoform 1 precursor [Homo
sapiens]
Length = 986
Score = 569 bits (1467), Expect = e-162
Identities = 270/514 (52%), Positives = 368/514 (71%), Gaps = 8/514 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+DS T ELGW+ +P GWEE+SG DE+ IRTYQVCNV + SQNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D K + E+ + K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+DLG R++K+NTE+R GPV++ GFYLAFQD G C++L++VRV+++KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
++N A+F +T+ +S SLV RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E E G +C+ C G +KA G+ C CP +S T +G+ NC C N Y+RAD DP M
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
CT PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG C C NV
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
++ PRQ GLT + ++DLLAHT YTFEI AVNGV++ S QFA+V+ITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ + + +SI+LSW +P+ PNG+ILDYE++YYEK+ E + T +++ VT+ LK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
IYVFQ+RART AGYG S K F+T + Y
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEY 533
>gi|21396504 ephrin receptor EphB2 isoform 2 precursor [Homo
sapiens]
Length = 987
Score = 569 bits (1467), Expect = e-162
Identities = 270/514 (52%), Positives = 368/514 (71%), Gaps = 8/514 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+DS T ELGW+ +P GWEE+SG DE+ IRTYQVCNV + SQNNWLRT ++
Sbjct: 20 EETLMDSTTATAELGWMVHPPSGWEEVSGYDENMNTIRTYQVCNVFESSQNNWLRTKFIR 79
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +I+VE+KF++RDC+SIP V G+CKETFNLYY E+D D K + E+ + K+D
Sbjct: 80 RRGAHRIHVEMKFSVRDCSSIPSVPGSCKETFNLYYYEADFDSATKTFPNWMENPWVKVD 139
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+DLG R++K+NTE+R GPV++ GFYLAFQD G C++L++VRV+++KCP
Sbjct: 140 TIAADESFSQVDLGGRVMKINTEVRSFGPVSRSGFYLAFQDYGGCMSLIAVRVFYRKCPR 199
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
++N A+F +T+ +S SLV RGSC+ N++E D P ++YC+ +GEWLVPIG+C C AG
Sbjct: 200 IIQNGAIFQETLSGAESTSLVAARGSCIANAEEVDVPIKLYCNGDGEWLVPIGRCMCKAG 259
Query: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E E G +C+ C G +KA G+ C CP +S T +G+ NC C N Y+RAD DP M
Sbjct: 260 FEAVENGTVCRGCPSGTFKANQGDEACTHCPINSRTTSEGATNCVCRNGYYRADLDPLDM 319
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
CT PS+P+ VIS++NETS++L+W+ P D+GGR+D+ +NIICK CG C C NV
Sbjct: 320 PCTTIPSAPQAVISSVNETSLMLEWTPPRDSGGREDLVYNIICKSCGSGRGACTRCGDNV 379
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
++ PRQ GLT + ++DLLAHT YTFEI AVNGV++ S QFA+V+ITTNQAAPS V
Sbjct: 380 QYAPRQLGLTEPRIYISDLLAHTQYTFEIQAVNGVTDQSPFSPQFASVNITTNQAAPSAV 439
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ + + +SI+LSW +P+ PNG+ILDYE++YYEK+ E + T +++ VT+ LK
Sbjct: 440 SIMHQVSRTVDSITLSWSQPDQPNGVILDYELQYYEKELSEYNATAIKSPTNTVTVQGLK 499
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
IYVFQ+RART AGYG S K F+T + Y
Sbjct: 500 AGAIYVFQVRARTVAGYGRYSGKMYFQTMTEAEY 533
>gi|4758284 ephrin receptor EphB1 precursor [Homo sapiens]
Length = 984
Score = 556 bits (1434), Expect = e-158
Identities = 267/513 (52%), Positives = 357/513 (69%), Gaps = 7/513 (1%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+D++T ELGW + P+ GWEE+SG DE+ IRTYQVCNV + +QNNWL T ++
Sbjct: 19 EETLMDTRTATAELGWTANPASGWEEVSGYDENLNTIRTYQVCNVFEPNQNNWLLTTFIN 78
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFTKID 144
R A +IY E++FT+RDC+S+P V G+CKETFNLYY E+D K + E + K+D
Sbjct: 79 RRGAHRIYTEMRFTVRDCSSLPNVPGSCKETFNLYYYETDSVIATKKSAFWSEAPYLKVD 138
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIAADESF+Q+D G R++K+NTE+R GP+ + GFYLAFQD GAC++L+SVRV+FKKCP
Sbjct: 139 TIAADESFSQVDFGGRLMKVNTEVRSFGPLTRNGFYLAFQDYGACMSLLSVRVFFKKCPS 198
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
V+N A+FP+T+ +S SLV RG+C+ N++E D P ++YC+ +GEW+VPIG+C+C G
Sbjct: 199 IVQNFAVFPETMTGAESTSLVIARGTCIPNAEEVDVPIKLYCNGDGEWMVPIGRCTCKPG 258
Query: 263 YE-ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMA 321
YE E C+AC G +KA C+ CP +S + + S C C Y+RAD DPP +A
Sbjct: 259 YEPENSVACKACPAGTFKASQEAEGCSHCPSNSRSPAEASPICTCRTGYYRADFDPPEVA 318
Query: 322 CTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
CT PS PRNVIS +NETS+IL+W P +TGGR DVT+NIICKKC + + C C NV
Sbjct: 319 CTSVPSGPRNVISIVNETSIILEWHPPRETGGRDDVTYNIICKKCRADRRSCSRCDDNVE 378
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
F+PRQ GLT V+++ L AHT YTF+I A+NGVS S P Q +V+ITTNQAAPS V
Sbjct: 379 FVPRQLGLTECRVSISSLWAHTPYTFDIQAINGVSSKSPFPPQHVSVNITTNQAAPSTVP 438
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+ + + SI+LSW +PE PNGIILDYE++YYEK+ E + ++ R++ I L+P
Sbjct: 439 IMHQVSATMRSITLSWPQPEQPNGIILDYEIRYYEKEHNEFNSSMARSQTNTARIDGLRP 498
Query: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+YV Q+RART AGYG S K F+T D Y
Sbjct: 499 GMVYVVQVRARTVAGYGKFSGKMCFQTLTDDDY 531
>gi|55770892 ephrin receptor EphA8 isoform 2 precursor [Homo
sapiens]
Length = 495
Score = 554 bits (1427), Expect = e-158
Identities = 252/408 (61%), Positives = 318/408 (77%), Gaps = 1/408 (0%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
EVNLLD+ TI G+ GW++YP+HGW+ I+ VDE + PI TYQVCNVM +QNNWLRT+WVP
Sbjct: 31 EVNLLDTSTIHGDWGWLTYPAHGWDSINEVDESFQPIHTYQVCNVMSPNQNNWLRTSWVP 90
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIAA 148
R+ A+++Y E+KFTLRDCNS+P VLGTCKETFNLYY+ESD D G +E QF KIDTIAA
Sbjct: 91 RDGARRVYAEIKFTLRDCNSMPGVLGTCKETFNLYYLESDRDLGASTQESQFLKIDTIAA 150
Query: 149 DESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKN 208
DESFT DLG R LKLNTE+R VGP++K+GFYLAFQD+GAC+A++S+R+Y+KKCP V+N
Sbjct: 151 DESFTGADLGVRRLKLNTEVRSVGPLSKRGFYLAFQDIGACLAILSLRIYYKKCPAMVRN 210
Query: 209 LAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCSCNAGYEERG 267
LA F + V DS SLVEVRG CV +S+E D P+MYCS EGEWLVPIGKC C+AGYEER
Sbjct: 211 LAAFSEAVTGADSSSLVEVRGQCVRHSEERDTPKMYCSAEGEWLVPIGKCVCSAGYEERR 270
Query: 268 FMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPS 327
C AC GFYK+ G+ CA+CPPHS + + C C+ +Y+RA DPPS ACTRPPS
Sbjct: 271 DACVACELGFYKSAPGDQLCARCPPHSHSAAPAAQACHCDLSYYRAALDPPSSACTRPPS 330
Query: 328 SPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
+P N+IS++N TSV L+W+ PLD GGR D+T+N +C++C W + +CE C RF+P+Q
Sbjct: 331 APVNLISSVNGTSVTLEWAPPLDPGGRSDITYNAVCRRCPWALSRCEACGSGTRFVPQQT 390
Query: 388 GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
L ++ V +LLAH NY+F I+AVNGVS+LS PR+ A V+ITTNQA
Sbjct: 391 SLVQASLLVANLLAHMNYSFWIEAVNGVSDLSPEPRRAAVVNITTNQA 438
>gi|17975768 ephrin receptor EphB3 precursor [Homo sapiens]
Length = 998
Score = 535 bits (1379), Expect = e-152
Identities = 262/513 (51%), Positives = 347/513 (67%), Gaps = 16/513 (3%)
Query: 29 EVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWVP 88
E L+D+K + EL W S+P GWEE+SG DE PIRTYQVCNV + SQNNWLRT ++
Sbjct: 39 EETLMDTKWVTSELAWTSHPESGWEEVSGYDEAMNPIRTYQVCNVRESSQNNWLRTGFIW 98
Query: 89 RNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDD----HGVKFREHQFTKID 144
R Q++YVELKFT+RDCNSIP + G+CKETFNL+Y E+D D + E+ + K+D
Sbjct: 99 RRDVQRVYVELKFTVRDCNSIPNIPGSCKETFNLFYYEADSDVASASSPFWMENPYVKVD 158
Query: 145 TIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPF 204
TIA DESF+++D G ++NT++R GP++K GFYLAFQD GAC++L+SVR ++KKC
Sbjct: 159 TIAPDESFSRLDAG----RVNTKVRSFGPLSKAGFYLAFQDQGACMSLISVRAFYKKCAS 214
Query: 205 TVKNLAMFPDTVP-MDSQSLVEVRGSCVNNSKEEDPP-RMYCSTEGEWLVPIGKCSCNAG 262
T A+FP+T+ + SLV G+C+ N+ E P ++YC+ +GEW+VP+G C+C G
Sbjct: 215 TTAGFALFPETLTGAEPTSLVIAPGTCIPNAVEVSVPLKLYCNGDGEWMVPVGACTCATG 274
Query: 263 YE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
+E + C+ C PG YKA G C CPP+S T + C C NN++RAD D
Sbjct: 275 HEPAAKESQCRPCPPGSYKAKQGEGPCLPCPPNSRTTSPAASICTCHNNFYRADSDSADS 334
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKC--GWNIKQCEPCSP 378
ACT PS PR VISN+NETS+IL+WS P D GGR D+ +N+ICKKC C C
Sbjct: 335 ACTTVPSPPRGVISNVNETSLILEWSEPRDLGGRDDLLYNVICKKCHGAGGASACSRCDD 394
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
NV F+PRQ GLT V ++ LLAHT YTFE+ AVNGVS S P ++AAV+ITTNQAAPS
Sbjct: 395 NVEFVPRQLGLTERRVHISHLLAHTRYTFEVQAVNGVSGKSPLPPRYAAVNITTNQAAPS 454
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
V T++ +S +S++LSW PE PNG+ILDYE+KY+EK E S + ++ +V +
Sbjct: 455 EVPTLRLHSSSGSSLTLSWAPPERPNGVILDYEMKYFEKSEGIAS--TVTSQMNSVQLDG 512
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
L+PD YV Q+RART AGYG SR EFET+ +
Sbjct: 513 LRPDARYVVQVRARTVAGYGQYSRPAEFETTSE 545
>gi|150456460 EPH receptor A10 isofom 3 [Homo sapiens]
Length = 1008
Score = 521 bits (1343), Expect = e-148
Identities = 263/522 (50%), Positives = 355/522 (68%), Gaps = 22/522 (4%)
Query: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
Query: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
Query: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDS-QSLVEVRGSCVNNSKEE-- 237
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + +LVEV G+CV +S+ E
Sbjct: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
Query: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQ 297
PPRM+C +GEWLVP+G+CSC+AG++ERG C+AC PGFYK C+ CP HS
Sbjct: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCSPCPEHSRAL 309
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSW--PLDTGGRK 355
E+ S C C+++Y R+ DPPS +CTRPPS+PR++ +++ + ++L W P D+GGR
Sbjct: 310 ENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWLPPADSGGRS 369
Query: 356 DVTFNIICKKCGWN--IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
DVT++++C +CG CEPC P V FLPRQ GL T+ L YT + A+N
Sbjct: 370 DVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGARYTVRVAALN 429
Query: 414 GVS-ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEP---EHPNGIILD 469
GVS ++ +A V+++T AP I++DR S+SLSW+EP P +
Sbjct: 430 GVSGPAAAAGTTYAQVTVSTGPGAPWEEDEIRRDRVEPQSVSLSWREPIPAGAPGANDTE 489
Query: 470 YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
YE++YYEK + E +Y++++ VT+++LKP T YVFQIRA
Sbjct: 490 YEIRYYEKGQSEQTYSMVKTGAPTVTVTNLKPATRYVFQIRA 531
>gi|32967311 ephrin receptor EphA2 [Homo sapiens]
Length = 976
Score = 468 bits (1203), Expect = e-132
Identities = 239/509 (46%), Positives = 321/509 (63%), Gaps = 12/509 (2%)
Query: 29 EVNLLDSKTIQGELGWISYP-SHGWEEISGVDEHYTPIRTYQVCNVMDHSQNNWLRTNWV 87
EV LLD GELGW+++P GW+ + + PI Y VCNVM Q+NWLRTNWV
Sbjct: 28 EVVLLDFAAAGGELGWLTHPYGKGWDLMQNIMNDM-PIYMYSVCNVMSGDQDNWLRTNWV 86
Query: 88 PRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVKFREHQFTKIDTIA 147
R A++I++ELKFT+RDCNS P +CKETFNLYY ESD D+G F++ FTKIDTIA
Sbjct: 87 YRGEAERIFIELKFTVRDCNSFPGGASSCKETFNLYYAESDLDYGTNFQKRLFTKIDTIA 146
Query: 148 ADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVK 207
DE D R +KLN E R VGP+ +KGFYLAFQD+GACVAL+SVRVY+KKCP ++
Sbjct: 147 PDEITVSSDFEARHVKLNVEERSVGPLTRKGFYLAFQDIGACVALLSVRVYYKKCPELLQ 206
Query: 208 NLAMFPDTVP-MDSQSLVEVRGSCVNNS---KEEDPPRMYCSTEGEWLVPIGKCSCNAGY 263
LA FP+T+ D+ SL V G+CV+++ + PRM+C+ +GEWLVPIG+C C AGY
Sbjct: 207 GLAHFPETIAGSDAPSLATVAGTCVDHAVVPPGGEEPRMHCAVDGEWLVPIGQCLCQAGY 266
Query: 264 EERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACT 323
E+ CQAC PGF+K C +CP H+ +G+ +C CE +FRA +DP SM CT
Sbjct: 267 EKVEDACQACSPGFFKFEASESPCLECPEHTLPSPEGATSCECEEGFFRAPQDPASMPCT 326
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
RPPS+P + + V L W+ P D+GGR+D+ +++ C++C +C PC +VR+
Sbjct: 327 RPPSAPHYLTAVGMGAKVELRWTPPQDSGGREDIVYSVTCEQCWPESGECGPCEASVRYS 386
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
GLT T+VTV+DL H NYTF ++A NGVS L + R F S++ NQ P V
Sbjct: 387 EPPHGLTRTSVTVSDLEPHMNYTFTVEARNGVSGLVT-SRSFRTASVSINQTEPPKV--- 442
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+ + S S+S+SW P + YEV Y K+ SY + R G +VT+ L PDT
Sbjct: 443 RLEGRSTTSLSVSWSIPPPQQSRVWKYEVT-YRKKGDSNSYNVRRTEGFSVTLDDLAPDT 501
Query: 504 IYVFQIRARTAAGYGTNSRKFEFET-SPD 531
Y+ Q++A T G G S+ EF+T SP+
Sbjct: 502 TYLVQVQALTQEGQGAGSKVHEFQTLSPE 530
>gi|194097332 ephrin receptor EphB6 precursor [Homo sapiens]
Length = 1021
Score = 404 bits (1037), Expect = e-112
Identities = 222/577 (38%), Positives = 329/577 (57%), Gaps = 58/577 (10%)
Query: 1 MDCQLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDE 60
M C L +LLL+S SVL + E LLD+ E+GW++YP GW+E+S +D+
Sbjct: 16 MVCSLWVLLLVS-SVL----------ALEEVLLDTTGETSEIGWLTYPPGGWDEVSVLDD 64
Query: 61 HYTPIRTYQVCNVMDH----SQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTC 116
RT++ C+V Q+NWL+T++V R AQ+ ++ L F++R C+S+ + GTC
Sbjct: 65 QRRLTRTFEACHVAGAPPGTGQDNWLQTHFVERRGAQRAHIRLHFSVRACSSLGVSGGTC 124
Query: 117 KETFNLYYMESDD----DHGVKFREHQFTKIDTIAADESFTQMD---------------- 156
+ETF LYY ++++ D + ++TK+DTIAADESF
Sbjct: 125 RETFTLYYRQAEEPDSPDSVSSWHLKRWTKVDTIAADESFPSSSSSSSSSSSAAWAVGPH 184
Query: 157 -LGDRI-LKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPD 214
G R L+LN + R GP+ ++GFY+AFQD GAC+ALV+VR++ CP +++ A FP+
Sbjct: 185 GAGQRAGLQLNVKERSFGPLTQRGFYVAFQDTGACLALVAVRLFSYTCPAVLRSFASFPE 244
Query: 215 TVPMDS--QSLVEVRGSCVNNSKEED----------PPRMYCSTEGEWLVPIGKCSCNAG 262
T + SLV G+CV +++ E+ PPR++C+ EG+W+V +G C C G
Sbjct: 245 TQASGAGGASLVAAVGTCVAHAEPEEDGVGGQAGGSPPRLHCNGEGKWMVAVGGCRCQPG 304
Query: 263 YEE-RGFM-CQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSM 320
Y+ RG CQAC G YK+ GN C+ CP S + C C ++RA DPP
Sbjct: 305 YQPARGDKACQACPRGLYKSSAGNAPCSPCPARSHAPNPAAPVCPCLEGFYRASSDPPEA 364
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQ-------C 373
CT PPS+P+ + + ++++L W P + GGR D+ FN++CK+C + C
Sbjct: 365 PCTGPPSAPQELWFEVQGSALMLHWRLPRELGGRGDLLFNVVCKECEGRQEPASGGGGTC 424
Query: 374 EPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTN 433
C V F PRQ GLT + V V L AH Y E+ AVNGVSELS P Q AA++++T+
Sbjct: 425 HRCRDEVHFDPRQRGLTESRVLVGGLRAHVPYILEVQAVNGVSELSPDPPQAAAINVSTS 484
Query: 434 QAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTN 493
PS V + + + NSI++SW +P+ NG ILDY+++YY++ E E+ L +
Sbjct: 485 HEVPSAVPVVHQVSRASNSITVSWPQPDQTNGNILDYQLRYYDQAEDESHSFTLTSETNT 544
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
T++ L P IY FQ+RARTAAG+G K F+T P
Sbjct: 545 ATVTQLSPGHIYGFQVRARTAAGHGPYGGKVYFQTLP 581
>gi|32528301 EPH receptor B4 precursor [Homo sapiens]
Length = 987
Score = 384 bits (986), Expect = e-106
Identities = 205/516 (39%), Positives = 301/516 (58%), Gaps = 16/516 (3%)
Query: 29 EVNLLDSKTIQGELGWISYPSHG--WEEISGVDEHYTPIRTYQVCNVMDH-SQNNWLRTN 85
E LL++K +L W+++P WEE+SG+DE +RTY+VC+V Q +WLRT
Sbjct: 17 EETLLNTKLETADLKWVTFPQVDGQWEELSGLDEEQHSVRTYEVCDVQRAPGQAHWLRTG 76
Query: 86 WVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDHGVK----FREHQFT 141
WVPR A +Y L+FT+ +C S+P +CKETF ++Y ESD D + E+ +
Sbjct: 77 WVPRRGAVHVYATLRFTMLECLSLPRAGRSCKETFTVFYYESDADTATALTPAWMENPYI 136
Query: 142 KIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSVRVYFKK 201
K+DT+AA+ + + K+N + +GP++K GFYLAFQD GAC+AL+S+ +++KK
Sbjct: 137 KVDTVAAEHLTRKRPGAEATGKVNVKTLRLGPLSKAGFYLAFQDQGACMALLSLHLFYKK 196
Query: 202 CPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEED--PPRMYCSTEGEWLV-PIGKCS 258
C NL FP+TVP + +V V GSCV ++ P +YC +G+W P+ CS
Sbjct: 197 CAQLTVNLTRFPETVPREL--VVPVAGSCVVDAVPAPGPSPSLYCREDGQWAEQPVTGCS 254
Query: 259 CNAGYE--ERGFMCQACRPGFYKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKD 316
C G+E E C+AC G +K L G C CP +S + GS C+C YFRA D
Sbjct: 255 CAPGFEAAEGNTKCRACAQGTFKPLSGEGSCQPCPANSHSNTIGSAVCQCRVGYFRARTD 314
Query: 317 PPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPC 376
P CT PPS+PR+V+S +N +S+ L+WS PL++GGR+D+T+ + C++C C PC
Sbjct: 315 PRGAPCTTPPSAPRSVVSRLNGSSLHLEWSAPLESGGREDLTYALRCRECRPG-GSCAPC 373
Query: 377 SPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA 436
++ F P L V V L YTFE+ A+NGVS L++ P F V++TT++
Sbjct: 374 GGDLTFDPGPRDLVEPWVVVRGLRPDFTYTFEVTALNGVSSLATGPVPFEPVNVTTDREV 433
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEK-QEQETSYTILRARGTNVT 495
P V I+ R+S +S+SL+W P P+G +LDYEVKY+EK E +S L+
Sbjct: 434 PPAVSDIRVTRSSPSSLSLAWAVPRAPSGAVLDYEVKYHEKGAEGPSSVRFLKTSENRAE 493
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+ LK Y+ Q+RAR+ AGYG ++ +T D
Sbjct: 494 LRGLKRGASYLVQVRARSEAGYGPFGQEHHSQTQLD 529
>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
Length = 976
Score = 383 bits (983), Expect = e-106
Identities = 218/539 (40%), Positives = 307/539 (56%), Gaps = 28/539 (5%)
Query: 8 LLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWI-SYPSHGWEEISGVDEHYTPIR 66
L+LL C+ L + EV L+D+ QGELGW+ P GW E + + TP+
Sbjct: 11 LVLLLCAPLPPGAR-----AKEVTLMDTSKAQGELGWLLDPPKDGWSEQQQI-LNGTPLY 64
Query: 67 TYQVCNVMDHSQ-NNWLRTNWVPRNS-AQKIYVELKFTLRDCNSIPLVLGT--CKETFNL 122
YQ C + ++WLR+NW+ R A +++VEL+FT+RDC S P G CKETFNL
Sbjct: 65 MYQDCPMQGRRDTDHWLRSNWIYRGEEASRVHVELQFTVRDCKSFPGGAGPLGCKETFNL 124
Query: 123 YYMESDDDHGVKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLA 182
YMESD D G++ R F K+ T+AAD+SFT DL +KLN E +G + ++G YLA
Sbjct: 125 LYMESDQDVGIQLRRPLFQKVTTVAADQSFTIRDLVSGSVKLNVERCSLGRLTRRGLYLA 184
Query: 183 FQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNS----KEED 238
F + GACVALVSVRV++++CP T+ LA FPDT+P LVEV G+C+ ++ +
Sbjct: 185 FHNPGACVALVSVRVFYQRCPETLNGLAQFPDTLP-GPAGLVEVAGTCLPHARASPRPSG 243
Query: 239 PPRMYCSTEGEWLVPIGKCSCNAGYEE--RGFMCQACRPGFYKALDGNMKCAKCPPHSST 296
PRM+CS +GEWLVP+G+C C GYEE G C AC G Y+ C CP S+
Sbjct: 244 APRMHCSPDGEWLVPVGRCHCEPGYEEGGSGEACVACPSGSYRMDMDTPHCLTCPQQSTA 303
Query: 297 QEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKD 356
+ +G+ C CE+ ++RA + P +ACT PPS+PRN+ + + T + L W P DTGGR+D
Sbjct: 304 ESEGATICTCESGHYRAPGEGPQVACTGPPSAPRNLSFSASGTQLSLRWEPPADTGGRQD 363
Query: 357 VTFNIICKKCGWNIKQ---CEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
V +++ C +C + C+PC V F P GLT V V L + NYTF ++A N
Sbjct: 364 VRYSVRCSQCQGTAQDGGPCQPCGVGVHFSPGARGLTTPAVHVNGLEPYANYTFNVEAQN 423
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSW--QEPEHPNGIILDYE 471
GVS L S +VSI+ A L+++ + + L+W P P G L YE
Sbjct: 424 GVSGLGSSGHASTSVSISMGHAESLSGLSLRLVKKEPRQLELTWAGSRPRSP-GANLTYE 482
Query: 472 VKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
+ + Q++E +L R V ++ L+PDT Y+ ++R T G G S EF TSP
Sbjct: 483 L-HVLNQDEERYQMVLEPR---VLLTELQPDTTYIVRVRMLTPLGPGPFSPDHEFRTSP 537
>gi|150456469 EPH receptor A10 isoform 2 [Homo sapiens]
Length = 295
Score = 324 bits (831), Expect = 1e-88
Identities = 161/274 (58%), Positives = 206/274 (75%), Gaps = 14/274 (5%)
Query: 4 QLSILLLLSCSVLDSFGELIPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYT 63
QL + LLL G P + EV LLDSK Q ELGW + PS+GWEEISGVDEH
Sbjct: 18 QLCLALLL--------GPWRPGTAEEVILLDSKASQAELGWTALPSNGWEEISGVDEHDR 69
Query: 64 PIRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLY 123
PIRTYQVCNV++ +Q+NWL+T W+ R Q+I+VEL+FTLRDC+SIP GTCKETFN+Y
Sbjct: 70 PIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAGTCKETFNVY 129
Query: 124 YMESDDDHG---VKFREHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFY 180
Y+E++ D G + + KIDTIAADESFTQ DLG+R +KLNTE+RE+GP++++GF+
Sbjct: 130 YLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSRRGFH 189
Query: 181 LAFQDVGACVALVSVRVYFKKCPFTVKNLAMFPDTVPMDS-QSLVEVRGSCVNNSKEE-- 237
LAFQDVGACVALVSVRVY+K+C TV+ LA FP T + +LVEV G+CV +S+ E
Sbjct: 190 LAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTCVAHSEGEPG 249
Query: 238 DPPRMYCSTEGEWLVPIGKCSCNAGYEERGFMCQ 271
PPRM+C +GEWLVP+G+CSC+AG++ERG C+
Sbjct: 250 SPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCE 283
>gi|222537743 protein tyrosine phosphatase, receptor type, Q [Homo
sapiens]
Length = 2299
Score = 72.8 bits (177), Expect = 8e-13
Identities = 48/151 (31%), Positives = 77/151 (50%), Gaps = 9/151 (5%)
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
FL G + T V V++++ T Y I +++ + +SP + +TTN P P +
Sbjct: 7 FLLLFIGTSETQVDVSNVVPGTRYDITISSIS--TTYTSPVTRI----VTTNVTKPGPPV 60
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEK-QEQETSYTILRAR--GTNVTISS 498
+ +R I LSW P +PNG I+ Y VKY E +T YT +R++ V +++
Sbjct: 61 FLAGERVGSAGILLSWNTPPNPNGRIISYIVKYKEVCPWMQTVYTQVRSKPDSLEVLLTN 120
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETS 529
L P T Y ++ A +AG G S F F+T+
Sbjct: 121 LNPGTTYEIKVAAENSAGIGVFSDPFLFQTA 151
Score = 60.5 bits (145), Expect = 4e-09
Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 32/211 (15%)
Query: 317 PPSMACTRP----PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIK 371
PP++ R PSS + + NI+ +S++L W P G K + I + N
Sbjct: 556 PPTVLSVRTRQQVPSSIKIINYKNISSSSILLYWDPPEYPNG-KITHYTIYAMELDTN-- 612
Query: 372 QCEPCSPNVRFLPRQFGLT--NTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAA 427
R F +T + + +T L +T Y + A G S LS F
Sbjct: 613 -------------RAFQITTIDNSFLITGLKKYTKYKMRVAASTHVGESSLSEENDIFVR 659
Query: 428 VSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTIL 487
S +++P V I + + I L W PE PNGII+ YEV Y + +T Y +
Sbjct: 660 TSEDEPESSPQDVEVID---VTADEIRLKWSPPEKPNGIIIAYEVLY---KNIDTLY-MK 712
Query: 488 RARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
T++ + +L+P T+Y +R+ T G+G
Sbjct: 713 NTSTTDIILRNLRPHTLYNISVRSYTRFGHG 743
Score = 58.5 bits (140), Expect = 1e-08
Identities = 62/225 (27%), Positives = 91/225 (40%), Gaps = 32/225 (14%)
Query: 323 TRPPSSPRNVI-SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVR 381
T P S+P N+ NI+ + L + P G + I K+ N +
Sbjct: 757 TVPDSAPENITYKNISSGEIELSFLPPSSPNGIIQ-KYTIYLKRSNGNEE---------- 805
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP-SPV 440
R T+ T + L +T Y E+ A S L + A +SI T + AP SP
Sbjct: 806 ---RTINTTSLTQNIKVLKKYTQYIIEVSA----STLKGEGVRSAPISILTEEDAPDSPP 858
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ S ++ LSWQ P PNGIIL Y V + + +T + T++ +S L
Sbjct: 859 QDFSVKQLSGVTVKLSWQPPLEPNGIILYYTVYVWNRSSLKT----INVTETSLELSDLD 914
Query: 501 PDTIYVFQIRARTAAGYG-TNSRKFEFET-------SPDCMYYFN 537
+ Y + A T G G T S F+T P +YY N
Sbjct: 915 YNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPKDVYYAN 959
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/94 (32%), Positives = 45/94 (47%), Gaps = 6/94 (6%)
Query: 428 VSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTIL 487
V TT ++ P V ++ TS S+ + W P+ NGII Y V E + T +
Sbjct: 1331 VKFTTQESVPDVVQNMQCMATSWQSVLVKWDPPKKANGIITQYMVTV------ERNSTKV 1384
Query: 488 RARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS 521
+ T L +T YVF++RA T+AG G S
Sbjct: 1385 SPQDHMYTFIKLLANTSYVFKVRASTSAGEGDES 1418
Score = 46.6 bits (109), Expect = 6e-05
Identities = 36/122 (29%), Positives = 53/122 (43%), Gaps = 7/122 (5%)
Query: 405 YTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP--SPVLTIKKDRTSRNSISLSWQEPEH 462
YT I + +E A + I T + P SP++ K+ +S S+ LSW P
Sbjct: 1118 YTDYILKITPSTEKGFSDTYTAQLYIKTEEDVPETSPIINTFKNLSS-TSVLLSWDPPVK 1176
Query: 463 PNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSR 522
PNG I+ Y++ E + T + + L P T+Y F ART G G +S
Sbjct: 1177 PNGAIISYDLTLQGPNENYSFIT----SDNYIILEELSPFTLYSFFAAARTRKGLGPSSI 1232
Query: 523 KF 524
F
Sbjct: 1233 LF 1234
Score = 45.4 bits (106), Expect = 1e-04
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 7/125 (5%)
Query: 399 LLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQ 458
L+ T + + A + E PP +S+ T Q PS + I S +SI L W
Sbjct: 536 LVPFTEHMISVSAFTIMGE--GPP---TVLSVRTRQQVPSSIKIINYKNISSSSILLYWD 590
Query: 459 EPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
PE+PNG I Y + Y + + ++ I + I+ LK T Y ++ A T G
Sbjct: 591 PPEYPNGKITHYTI-YAMELDTNRAFQITTI-DNSFLITGLKKYTKYKMRVAASTHVGES 648
Query: 519 TNSRK 523
+ S +
Sbjct: 649 SLSEE 653
Score = 45.4 bits (106), Expect = 1e-04
Identities = 41/149 (27%), Positives = 60/149 (40%), Gaps = 18/149 (12%)
Query: 395 TVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSIS 454
T LLA+T+Y F++ A E + T + PS I S +
Sbjct: 1392 TFIKLLANTSYVFKVRASTSAGEGDESTCHVS----TLPETVPSVPTNIAFSDVQSTSAT 1447
Query: 455 LSWQEPEHPNGIILDYEV---------KYYEKQE----QETSYTILRARGTNVTISSLKP 501
L+W P+ G +Y++ K +E +E Q+ Y + A T T+ LK
Sbjct: 1448 LTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQKIQY-LYEAHLTEETVYGLKK 1506
Query: 502 DTIYVFQIRARTAAGYGTNSRKFEFETSP 530
Y FQ+ A T AGYG S +T P
Sbjct: 1507 FRWYRFQVAASTNAGYGNASNWISTKTLP 1535
Score = 42.7 bits (99), Expect = 8e-04
Identities = 54/212 (25%), Positives = 84/212 (39%), Gaps = 40/212 (18%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P S P++ + ++ +V L W PL+ G + WN R
Sbjct: 854 PDSPPQDFSVKQLSGVTVKLSWQPPLEPNG-----IILYYTVYVWN-----------RSS 897
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDA-VNGVSELSSPPRQFAAVSITTNQAAPS-PVL 441
+ +T T++ ++DL +Y E A V + + +S T + APS P
Sbjct: 898 LKTINVTETSLELSDL----DYNVEYSAYVTASTRFGDGKTRSNIISFQTPEGAPSDPPK 953
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--------ARGTN 493
+ S +SI L W P PNGII Y V Y + TS T ++ N
Sbjct: 954 DVYYANLSSSSIILFWTPPSKPNGIIQYYSVYY-----RNTSGTFMQNFTLHEVTNDFDN 1008
Query: 494 VTISS----LKPDTIYVFQIRARTAAGYGTNS 521
+T+S+ L + Y F + A T+ G G S
Sbjct: 1009 MTVSTIIDKLTIFSYYTFWLTASTSVGNGNKS 1040
Score = 39.7 bits (91), Expect = 0.007
Identities = 47/213 (22%), Positives = 86/213 (40%), Gaps = 27/213 (12%)
Query: 325 PPSSPR-NVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P +SP N N++ TSV+L W P+ G +++++ + PN +
Sbjct: 1150 PETSPIINTFKNLSSTSVLLSWDPPVKPNGAI-ISYDLTLQ------------GPNENY- 1195
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP-SPVLT 442
F ++ + + +L T Y+F A S + + T+++ P +P
Sbjct: 1196 --SFITSDNYIILEELSPFTLYSFFAAARTRKGLGPS-----SILFFYTDESVPLAPPQN 1248
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ + + + L W P GI+ Y K +E + Y + T + L+P
Sbjct: 1249 LTLINCTSDFVWLKWSPSPLPGGIVKVYSFKIHEHETDTIYYKNISGFKTEAKLVGLEPV 1308
Query: 503 TIYVFQIRARTAAGYG---TNSRKFEFETS-PD 531
+ Y ++ A T G G +N KF + S PD
Sbjct: 1309 STYSIRVSAFTKVGNGNQFSNVVKFTTQESVPD 1341
Score = 39.3 bits (90), Expect = 0.009
Identities = 32/140 (22%), Positives = 61/140 (43%), Gaps = 19/140 (13%)
Query: 336 INETSVILDWSWPLDTGGRKDVTFNIICKK-CGWNIKQCEPCSPNVRFLPRQFGLTNTTV 394
+ ++L W+ P + GR +++ + K+ C W + VR P + V
Sbjct: 67 VGSAGILLSWNTPPNPNGRI-ISYIVKYKEVCPW----MQTVYTQVRSKP-----DSLEV 116
Query: 395 TVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
+T+L T Y ++ A N G+ S P T ++AP V+ + + + ++
Sbjct: 117 LLTNLNPGTTYEIKVAAENSAGIGVFSDP------FLFQTAESAPGKVVNLTVEAYNASA 170
Query: 453 ISLSWQEPEHPNGIILDYEV 472
+ L W P PNG I +++
Sbjct: 171 VKLIWYLPRQPNGKITSFKI 190
Score = 38.1 bits (87), Expect = 0.021
Identities = 42/210 (20%), Positives = 85/210 (40%), Gaps = 12/210 (5%)
Query: 325 PPSSPRNVI-SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P P++V +N++ +S+IL W+ P G +++ + Q + + +
Sbjct: 948 PSDPPKDVYYANLSSSSIILFWTPPSKPNGIIQY-YSVYYRNTSGTFMQ----NFTLHEV 1002
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL-T 442
F + + L + YTF + A V + + + + T+Q P +
Sbjct: 1003 TNDFDNMTVSTIIDKLTIFSYYTFWLTASTSVGNGN---KSSDIIEVYTDQDIPEGFVGN 1059
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ + S +I++SW P PNG++ Y V +Q L ++ +L+
Sbjct: 1060 LTYESISSTAINVSWVPPAQPNGLVF-YYVSLILQQTPRHVRPPLVTYERSIYFDNLEKY 1118
Query: 503 TIYVFQIRARTAAGYG-TNSRKFEFETSPD 531
T Y+ +I T G+ T + + +T D
Sbjct: 1119 TDYILKITPSTEKGFSDTYTAQLYIKTEED 1148
Score = 37.4 bits (85), Expect = 0.035
Identities = 22/74 (29%), Positives = 35/74 (47%), Gaps = 1/74 (1%)
Query: 401 AHTNYT-FEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQE 459
A TN T F + V +E S+ + +S+ T P V ++ + ++W++
Sbjct: 360 AFTNLTPFTMYDVYIAAETSAGTGPKSNISVFTPPDVPGAVFDLQLAEVESTQVRITWKK 419
Query: 460 PEHPNGIILDYEVK 473
P PNGII Y VK
Sbjct: 420 PRQPNGIINQYRVK 433
Score = 33.1 bits (74), Expect = 0.66
Identities = 38/139 (27%), Positives = 55/139 (39%), Gaps = 16/139 (11%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS-PVLTIKKDRTSRNSIS 454
VT L +T Y FE+ A ++ + + T ++ P P + S S
Sbjct: 270 VTHLRPYTTYLFEVSAA------TTEAGYIDSTIVRTPESVPEGPPQNCVTGNITGKSFS 323
Query: 455 LSWQEPEHPNGIILDYEVKYYEKQEQ--ETSYTILRARGTNVTISSLKPDTIYVFQIRAR 512
+ W P G Y V+ Y + + S L+ TN+T P T+Y I A
Sbjct: 324 ILWDPPTIVTGKF-SYRVELYGPSGRILDNSTKDLKFAFTNLT-----PFTMYDVYIAAE 377
Query: 513 TAAGYGTNSRKFEFETSPD 531
T+AG G S F T PD
Sbjct: 378 TSAGTGPKSNISVF-TPPD 395
Score = 32.7 bits (73), Expect = 0.86
Identities = 52/199 (26%), Positives = 76/199 (38%), Gaps = 23/199 (11%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGG---RKDVTFNIICKKCG-WNIKQCEPCSPNV 380
PS P N+ S++ TS L W P G +T + +KC W ++C +
Sbjct: 1430 PSVPTNIAFSDVQSTSATLTWIRPDTILGYFQNYKITTQLRAQKCKEWESEECVEYQ-KI 1488
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
++L + T TV L Y F++ A G S+ +S T P
Sbjct: 1489 QYL---YEAHLTEETVYGLKKFRWYRFQVAASTNAGYGNASN------WISTKTLPGPPD 1539
Query: 439 -PVLTIKKDRTSRNSISLSWQEP---EHPNGIILDYEVKYYEKQEQETSYTILRARGTNV 494
P + TS SIS+SW EP P ++D VK + E S+ +
Sbjct: 1540 GPPENVHVVATSPFSISISWSEPAVITGPTCYLID--VKSVDNDEFNISFIKSNEENKTI 1597
Query: 495 TISSLKPDTIYVFQIRART 513
I L+ T Y I A T
Sbjct: 1598 EIKDLEIFTRYSVVITAFT 1616
>gi|104487002 protein tyrosine phosphatase, receptor type, D isoform
5 precursor [Homo sapiens]
Length = 1502
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
A +PP +P V++ TS+ L W D+G + V++ II K K E +
Sbjct: 318 ALPKPPGTP--VVTESTATSITLTW----DSGNPEPVSYYIIQHKP----KNSEELYKEI 367
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
G+ T +V L +++Y F + AVN + PP + ++ T+ QA S
Sbjct: 368 D------GVATTRYSVAGLSPYSDYEFRVVAVNNIGR--GPPSE-PVLTQTSEQAPSSAP 418
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--ARGTNVTISS 498
++ S +I + W+EPE PNG I Y V Y Q + + A TI +
Sbjct: 419 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 478
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
L P Y ++ A T+ G G S + T
Sbjct: 479 LVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 508
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/257 (22%), Positives = 104/257 (40%), Gaps = 25/257 (9%)
Query: 278 YKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTR---PPSSPRNVIS 334
YK +DG S D NN R P + T P S+PR+V +
Sbjct: 364 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQA 423
Query: 335 N-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
++ T++++ W P + G+ G+ + + +V + +
Sbjct: 424 RMLSSTTILVQWKEPEEPNGQIQ----------GYRVYYTMDPTQHVNNWMKHNVADSQI 473
Query: 394 VTVTDLLAHTNYTFEIDAVNGVSE--LSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
T+ +L+ Y+ ++ A + + LSS + + T P L K + S
Sbjct: 474 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSD------IQVITQTGVPGQPLNFKAEPESET 527
Query: 452 SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
SI LSW P + I +YE+ Y + + E + GT+ + LKP+++Y F++ A
Sbjct: 528 SILLSWTPPR--SDTIANYELVYKDGEHGEEQRITIEP-GTSYRLQGLKPNSLYYFRLAA 584
Query: 512 RTAAGYGTNSRKFEFET 528
R+ G G ++ + T
Sbjct: 585 RSPQGLGASTAEISART 601
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
+ D+ NYT + GV E A++ T +A P P T ++ SI+L
Sbjct: 288 LNDVRQSANYTCVAMSTLGVIE---------AIAQITVKALPKPPGTPVVTESTATSITL 338
Query: 456 SWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAA 515
+W + +P + Y +++ K +E I T +++ L P + Y F++ A
Sbjct: 339 TW-DSGNPEPVSY-YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNI 396
Query: 516 GYGTNSRKFEFETS 529
G G S +TS
Sbjct: 397 GRGPPSEPVLTQTS 410
Score = 31.2 bits (69), Expect = 2.5
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+ S+ LSW+ PE+ N + +++ Y + + E + R T I +LKP+ Y F +
Sbjct: 617 KTSVLLSWEIPENYNS-AMPFKILYDDGKMVEE----VDGRATQKLIVNLKPEKSYSFVL 671
Query: 510 RARTAAGYGTNSRKFEFETSPDCM 533
R + G R +T+PD +
Sbjct: 672 TNRGNSAGGLQHR-VTAKTAPDVL 694
>gi|4506309 protein tyrosine phosphatase, receptor type, D isoform 1
precursor [Homo sapiens]
Length = 1912
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
A +PP +P V++ TS+ L W D+G + V++ II K K E +
Sbjct: 321 ALPKPPGTP--VVTESTATSITLTW----DSGNPEPVSYYIIQHKP----KNSEELYKEI 370
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
G+ T +V L +++Y F + AVN + PP + ++ T+ QA S
Sbjct: 371 D------GVATTRYSVAGLSPYSDYEFRVVAVNNIGR--GPPSE-PVLTQTSEQAPSSAP 421
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--ARGTNVTISS 498
++ S +I + W+EPE PNG I Y V Y Q + + A TI +
Sbjct: 422 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 481
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
L P Y ++ A T+ G G S + T
Sbjct: 482 LVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 511
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/257 (22%), Positives = 104/257 (40%), Gaps = 25/257 (9%)
Query: 278 YKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTR---PPSSPRNVIS 334
YK +DG S D NN R P + T P S+PR+V +
Sbjct: 367 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQA 426
Query: 335 N-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
++ T++++ W P + G+ G+ + + +V + +
Sbjct: 427 RMLSSTTILVQWKEPEEPNGQIQ----------GYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 394 VTVTDLLAHTNYTFEIDAVNGVSE--LSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
T+ +L+ Y+ ++ A + + LSS + + T P L K + S
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSD------IQVITQTGVPGQPLNFKAEPESET 530
Query: 452 SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
SI LSW P + I +YE+ Y + + E + GT+ + LKP+++Y F++ A
Sbjct: 531 SILLSWTPPR--SDTIANYELVYKDGEHGEEQRITIEP-GTSYRLQGLKPNSLYYFRLAA 587
Query: 512 RTAAGYGTNSRKFEFET 528
R+ G G ++ + T
Sbjct: 588 RSPQGLGASTAEISART 604
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/213 (26%), Positives = 89/213 (41%), Gaps = 29/213 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P PR VI++ + ++ W P+DT G + + + K EP +
Sbjct: 824 PGKPRLVINHTQMNTALIQWHPPVDTFGP------LQGYRLKFGRKDMEPLTT------L 871
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445
+F T TD+ +Y F + A N V ++ +SI P +
Sbjct: 872 EFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE---ISIPEEVPTGFPQ-NLHS 927
Query: 446 DRTSRNSISLSWQEP--EHPNGIILDYEVKYYE------KQEQETSYTILRARGTNVTIS 497
+ T+ S+ LSWQ P NGII Y + Y + EQ ++ T +T++
Sbjct: 928 EGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQ-----LIVPADTTMTLT 982
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
LKPDT Y ++RA T+ G G S +F T P
Sbjct: 983 GLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLP 1015
Score = 42.7 bits (99), Expect = 8e-04
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 426 AAVSITTNQAAPS-PVLTIKKDRTSRNSISLSWQEP--EHPNGIILDYEVKYYEKQ-EQE 481
A +S T Q+ PS P I S SI +SWQ P E NGII +Y +KY E +
Sbjct: 598 AEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDD 657
Query: 482 TSYTIL--RARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+ IL + T + L+ T Y + A T G G S T+ D
Sbjct: 658 KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Score = 37.7 bits (86), Expect = 0.027
Identities = 52/213 (24%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 325 PPSSPRNVISN-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P P+N+ S TSV L W P+ +T + + N+ L
Sbjct: 918 PTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYR-----------DINIPLL 966
Query: 384 PRQFGLT--NTTVTVTDLLAHTNYTFEIDAVNGVSELS-SPPRQFAAVSITTNQAAPSPV 440
P + + +TT+T+T L T Y ++ A SP QF + + A V
Sbjct: 967 PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHV 1026
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ K S+ LSW+ PE+ N + +++ Y + + E + R T I +LK
Sbjct: 1027 KAVMK-----TSVLLSWEIPENYNS-AMPFKILYDDGKMVEE----VDGRATQKLIVNLK 1076
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCM 533
P+ Y F + R + G R +T+PD +
Sbjct: 1077 PEKSYSFVLTNRGNSAGGLQHR-VTAKTAPDVL 1108
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
+ D+ NYT + GV E A++ T +A P P T ++ SI+L
Sbjct: 291 LNDVRQSANYTCVAMSTLGVIE---------AIAQITVKALPKPPGTPVVTESTATSITL 341
Query: 456 SWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAA 515
+W + +P + Y +++ K +E I T +++ L P + Y F++ A
Sbjct: 342 TW-DSGNPEPVSY-YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNI 399
Query: 516 GYGTNSRKFEFETS 529
G G S +TS
Sbjct: 400 GRGPPSEPVLTQTS 413
>gi|18860890 protein tyrosine phosphatase, receptor type, D isoform
2 precursor [Homo sapiens]
Length = 1899
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
A +PP +P V++ TS+ L W D+G + V++ II K K E +
Sbjct: 308 ALPKPPGTP--VVTESTATSITLTW----DSGNPEPVSYYIIQHKP----KNSEELYKEI 357
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
G+ T +V L +++Y F + AVN + PP + ++ T+ QA S
Sbjct: 358 D------GVATTRYSVAGLSPYSDYEFRVVAVNNIGR--GPPSE-PVLTQTSEQAPSSAP 408
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--ARGTNVTISS 498
++ S +I + W+EPE PNG I Y V Y Q + + A TI +
Sbjct: 409 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 468
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
L P Y ++ A T+ G G S + T
Sbjct: 469 LVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 498
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/257 (22%), Positives = 104/257 (40%), Gaps = 25/257 (9%)
Query: 278 YKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTR---PPSSPRNVIS 334
YK +DG S D NN R P + T P S+PR+V +
Sbjct: 354 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQA 413
Query: 335 N-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
++ T++++ W P + G+ G+ + + +V + +
Sbjct: 414 RMLSSTTILVQWKEPEEPNGQIQ----------GYRVYYTMDPTQHVNNWMKHNVADSQI 463
Query: 394 VTVTDLLAHTNYTFEIDAVNGVSE--LSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
T+ +L+ Y+ ++ A + + LSS + + T P L K + S
Sbjct: 464 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSD------IQVITQTGVPGQPLNFKAEPESET 517
Query: 452 SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
SI LSW P + I +YE+ Y + + E + GT+ + LKP+++Y F++ A
Sbjct: 518 SILLSWTPPR--SDTIANYELVYKDGEHGEEQRITIEP-GTSYRLQGLKPNSLYYFRLAA 574
Query: 512 RTAAGYGTNSRKFEFET 528
R+ G G ++ + T
Sbjct: 575 RSPQGLGASTAEISART 591
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/213 (26%), Positives = 89/213 (41%), Gaps = 29/213 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P PR VI++ + ++ W P+DT G + + + K EP +
Sbjct: 811 PGKPRLVINHTQMNTALIQWHPPVDTFGP------LQGYRLKFGRKDMEPLTT------L 858
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445
+F T TD+ +Y F + A N V ++ +SI P +
Sbjct: 859 EFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE---ISIPEEVPTGFPQ-NLHS 914
Query: 446 DRTSRNSISLSWQEP--EHPNGIILDYEVKYYE------KQEQETSYTILRARGTNVTIS 497
+ T+ S+ LSWQ P NGII Y + Y + EQ ++ T +T++
Sbjct: 915 EGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQ-----LIVPADTTMTLT 969
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
LKPDT Y ++RA T+ G G S +F T P
Sbjct: 970 GLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLP 1002
Score = 42.7 bits (99), Expect = 8e-04
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 426 AAVSITTNQAAPS-PVLTIKKDRTSRNSISLSWQEP--EHPNGIILDYEVKYYEKQ-EQE 481
A +S T Q+ PS P I S SI +SWQ P E NGII +Y +KY E +
Sbjct: 585 AEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDD 644
Query: 482 TSYTIL--RARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+ IL + T + L+ T Y + A T G G S T+ D
Sbjct: 645 KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 696
Score = 37.7 bits (86), Expect = 0.027
Identities = 52/213 (24%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 325 PPSSPRNVISN-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P P+N+ S TSV L W P+ +T + + N+ L
Sbjct: 905 PTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYR-----------DINIPLL 953
Query: 384 PRQFGLT--NTTVTVTDLLAHTNYTFEIDAVNGVSELS-SPPRQFAAVSITTNQAAPSPV 440
P + + +TT+T+T L T Y ++ A SP QF + + A V
Sbjct: 954 PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHV 1013
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ K S+ LSW+ PE+ N + +++ Y + + E + R T I +LK
Sbjct: 1014 KAVMK-----TSVLLSWEIPENYNS-AMPFKILYDDGKMVEE----VDGRATQKLIVNLK 1063
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCM 533
P+ Y F + R + G R +T+PD +
Sbjct: 1064 PEKSYSFVLTNRGNSAGGLQHR-VTAKTAPDVL 1095
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
+ D+ NYT + GV E A++ T +A P P T ++ SI+L
Sbjct: 278 LNDVRQSANYTCVAMSTLGVIE---------AIAQITVKALPKPPGTPVVTESTATSITL 328
Query: 456 SWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAA 515
+W + +P + Y +++ K +E I T +++ L P + Y F++ A
Sbjct: 329 TW-DSGNPEPVSY-YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNI 386
Query: 516 GYGTNSRKFEFETS 529
G G S +TS
Sbjct: 387 GRGPPSEPVLTQTS 400
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform
3 precursor [Homo sapiens]
Length = 1903
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
A +PP +P V++ TS+ L W D+G + V++ II K K E +
Sbjct: 321 ALPKPPGTP--VVTESTATSITLTW----DSGNPEPVSYYIIQHKP----KNSEELYKEI 370
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
G+ T +V L +++Y F + AVN + PP + ++ T+ QA S
Sbjct: 371 D------GVATTRYSVAGLSPYSDYEFRVVAVNNIGR--GPPSE-PVLTQTSEQAPSSAP 421
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--ARGTNVTISS 498
++ S +I + W+EPE PNG I Y V Y Q + + A TI +
Sbjct: 422 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 481
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
L P Y ++ A T+ G G S + T
Sbjct: 482 LVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 511
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/257 (22%), Positives = 104/257 (40%), Gaps = 25/257 (9%)
Query: 278 YKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTR---PPSSPRNVIS 334
YK +DG S D NN R P + T P S+PR+V +
Sbjct: 367 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQA 426
Query: 335 N-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
++ T++++ W P + G+ G+ + + +V + +
Sbjct: 427 RMLSSTTILVQWKEPEEPNGQIQ----------GYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 394 VTVTDLLAHTNYTFEIDAVNGVSE--LSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
T+ +L+ Y+ ++ A + + LSS + + T P L K + S
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSD------IQVITQTGVPGQPLNFKAEPESET 530
Query: 452 SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
SI LSW P + I +YE+ Y + + E + GT+ + LKP+++Y F++ A
Sbjct: 531 SILLSWTPPR--SDTIANYELVYKDGEHGEEQRITIEP-GTSYRLQGLKPNSLYYFRLAA 587
Query: 512 RTAAGYGTNSRKFEFET 528
R+ G G ++ + T
Sbjct: 588 RSPQGLGASTAEISART 604
Score = 63.2 bits (152), Expect = 6e-10
Identities = 57/213 (26%), Positives = 89/213 (41%), Gaps = 29/213 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P PR VI++ + ++ W P+DT G + + + K EP +
Sbjct: 815 PGKPRLVINHTQMNTALIQWHPPVDTFGP------LQGYRLKFGRKDMEPLTT------L 862
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKK 445
+F T TD+ +Y F + A N V ++ +SI P +
Sbjct: 863 EFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKE---ISIPEEVPTGFPQ-NLHS 918
Query: 446 DRTSRNSISLSWQEP--EHPNGIILDYEVKYYE------KQEQETSYTILRARGTNVTIS 497
+ T+ S+ LSWQ P NGII Y + Y + EQ ++ T +T++
Sbjct: 919 EGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQ-----LIVPADTTMTLT 973
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
LKPDT Y ++RA T+ G G S +F T P
Sbjct: 974 GLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLP 1006
Score = 42.7 bits (99), Expect = 8e-04
Identities = 37/112 (33%), Positives = 49/112 (43%), Gaps = 6/112 (5%)
Query: 426 AAVSITTNQAAPS-PVLTIKKDRTSRNSISLSWQEP--EHPNGIILDYEVKYYEKQ-EQE 481
A +S T Q+ PS P I S SI +SWQ P E NGII +Y +KY E +
Sbjct: 598 AEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDD 657
Query: 482 TSYTIL--RARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+ IL + T + L+ T Y + A T G G S T+ D
Sbjct: 658 KPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNED 709
Score = 37.7 bits (86), Expect = 0.027
Identities = 52/213 (24%), Positives = 86/213 (40%), Gaps = 26/213 (12%)
Query: 325 PPSSPRNVISN-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P P+N+ S TSV L W P+ +T + + N+ L
Sbjct: 909 PTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYR-----------DINIPLL 957
Query: 384 PRQFGLT--NTTVTVTDLLAHTNYTFEIDAVNGVSELS-SPPRQFAAVSITTNQAAPSPV 440
P + + +TT+T+T L T Y ++ A SP QF + + A V
Sbjct: 958 PMEQLIVPADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHV 1017
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ K S+ LSW+ PE+ N + +++ Y + + E + R T I +LK
Sbjct: 1018 KAVMK-----TSVLLSWEIPENYNS-AMPFKILYDDGKMVEE----VDGRATQKLIVNLK 1067
Query: 501 PDTIYVFQIRARTAAGYGTNSRKFEFETSPDCM 533
P+ Y F + R + G R +T+PD +
Sbjct: 1068 PEKSYSFVLTNRGNSAGGLQHR-VTAKTAPDVL 1099
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
+ D+ NYT + GV E A++ T +A P P T ++ SI+L
Sbjct: 291 LNDVRQSANYTCVAMSTLGVIE---------AIAQITVKALPKPPGTPVVTESTATSITL 341
Query: 456 SWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAA 515
+W + +P + Y +++ K +E I T +++ L P + Y F++ A
Sbjct: 342 TW-DSGNPEPVSY-YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNI 399
Query: 516 GYGTNSRKFEFETS 529
G G S +TS
Sbjct: 400 GRGPPSEPVLTQTS 413
>gi|18860894 protein tyrosine phosphatase, receptor type, D isoform
4 precursor [Homo sapiens]
Length = 1501
Score = 65.1 bits (157), Expect = 2e-10
Identities = 58/210 (27%), Positives = 91/210 (43%), Gaps = 21/210 (10%)
Query: 321 ACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNV 380
A +PP +P V++ TS+ L W D+G + V++ II K K E +
Sbjct: 321 ALPKPPGTP--VVTESTATSITLTW----DSGNPEPVSYYIIQHKP----KNSEELYKEI 370
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPV 440
G+ T +V L +++Y F + AVN + PP + ++ T+ QA S
Sbjct: 371 D------GVATTRYSVAGLSPYSDYEFRVVAVNNIGR--GPPSE-PVLTQTSEQAPSSAP 421
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILR--ARGTNVTISS 498
++ S +I + W+EPE PNG I Y V Y Q + + A TI +
Sbjct: 422 RDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGN 481
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
L P Y ++ A T+ G G S + T
Sbjct: 482 LVPQKTYSVKVLAFTSIGDGPLSSDIQVIT 511
Score = 63.5 bits (153), Expect = 5e-10
Identities = 57/257 (22%), Positives = 104/257 (40%), Gaps = 25/257 (9%)
Query: 278 YKALDGNMKCAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTR---PPSSPRNVIS 334
YK +DG S D NN R P + T P S+PR+V +
Sbjct: 367 YKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQA 426
Query: 335 N-INETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
++ T++++ W P + G+ G+ + + +V + +
Sbjct: 427 RMLSSTTILVQWKEPEEPNGQIQ----------GYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 394 VTVTDLLAHTNYTFEIDAVNGVSE--LSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
T+ +L+ Y+ ++ A + + LSS + + T P L K + S
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSD------IQVITQTGVPGQPLNFKAEPESET 530
Query: 452 SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
SI LSW P + I +YE+ Y + + E + GT+ + LKP+++Y F++ A
Sbjct: 531 SILLSWTPPR--SDTIANYELVYKDGEHGEEQRITIEP-GTSYRLQGLKPNSLYYFRLAA 587
Query: 512 RTAAGYGTNSRKFEFET 528
R+ G G ++ + T
Sbjct: 588 RSPQGLGASTAEISART 604
Score = 33.5 bits (75), Expect = 0.51
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 396 VTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
+ D+ NYT + GV E A++ T +A P P T ++ SI+L
Sbjct: 291 LNDVRQSANYTCVAMSTLGVIE---------AIAQITVKALPKPPGTPVVTESTATSITL 341
Query: 456 SWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAA 515
+W + +P + Y +++ K +E I T +++ L P + Y F++ A
Sbjct: 342 TW-DSGNPEPVSY-YIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNI 399
Query: 516 GYGTNSRKFEFETS 529
G G S +TS
Sbjct: 400 GRGPPSEPVLTQTS 413
Score = 31.2 bits (69), Expect = 2.5
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+ S+ LSW+ PE+ N + +++ Y + + E + R T I +LKP+ Y F +
Sbjct: 620 KTSVLLSWEIPENYNS-AMPFKILYDDGKMVEE----VDGRATQKLIVNLKPEKSYSFVL 674
Query: 510 RARTAAGYGTNSRKFEFETSPDCM 533
R + G R +T+PD +
Sbjct: 675 TNRGNSAGGLQHR-VTAKTAPDVL 697
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 63.2 bits (152), Expect = 6e-10
Identities = 58/199 (29%), Positives = 91/199 (45%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PPS+P +S I + S+++ W+ P+D GG ++ I+ K+ ++ + C+
Sbjct: 24904 PPSTPE--VSAITKDSMVVTWARPVDDGGT-EIEGYILEKRDKEGVRWTK-CNKKT---- 24955
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ + VT L +Y F + A N GV E S P + A P P
Sbjct: 24956 ----LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY---PPGPPSN 25008
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
K TSR+S+SL+W +P + G + EVK E T +G T++ L
Sbjct: 25009 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKL 25068
Query: 500 KPDTIYVFQIRARTAAGYG 518
K +T Y F+I A + G G
Sbjct: 25069 KENTEYNFRICAINSEGVG 25087
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 30/205 (14%)
Query: 324 RPPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSP 378
R P +P + +++ + + S ++ W+ P D G K +T I+ K+ W +P P
Sbjct: 17010 RVPDAPDQPIVTEVTKDSALVTWNKPHDGG--KPITNYILEKRETMSKRWARVTKDPIHP 17067
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQ-FAAVSITTNQA 435
+F V DLL Y F + A N G+ + S P + FA I A
Sbjct: 17068 YTKF------------RVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI----A 17111
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
PSP + + T+ NS+ L+WQ P H G IL Y V+Y + ++E ++T
Sbjct: 17112 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 17171
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T ++ L+ Y F++ A AAG
Sbjct: 17172 TKYKVTGLRDGQTYKFRVLAVNAAG 17196
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I + S+ + WS P+ GG D++ + K+ ++ + +R
Sbjct: 27068 PPGIPE--VTKITKNSMTVVWSRPIADGG-SDISGYFLEKRDKKSLGWFKVLKETIR--- 27121
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T VT L +++Y + + AVN G S P + A P P
Sbjct: 27122 ------DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID---PPGPPAK 27172
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
I+ ++++SI+L W +P + G + E++ E++E T T R T +S+L
Sbjct: 27173 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 27232
Query: 500 KPDTIYVFQIRARTAAGYG 518
KP Y F++ A AG G
Sbjct: 27233 KPGVNYYFRVSAVNCAGQG 27251
Score = 59.3 bits (142), Expect = 9e-09
Identities = 66/205 (32%), Positives = 94/205 (45%), Gaps = 36/205 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PPS+P V+ ++ ++SV L WS P D GG + VT G+ I++ E + VR
Sbjct: 30331 PPSNPPEVL-DVTKSSVSLSWSRPKDDGGSR-VT--------GYYIERKETSTDKWVRHN 30380
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELS--SPPRQFAAVSITTNQAAPSP 439
Q +T T TVT L+ Y F I A N G+SE S S P +Q
Sbjct: 30381 KTQ--ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKY-------YEKQEQETSYTILRARG 491
+L+I KD S++L W++PE G IL Y V+Y ++K +E R +
Sbjct: 30439 ILSISKD-----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE------RIKD 30487
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
TI L T Y F++ A G
Sbjct: 30488 KQFTIGGLLEATEYEFRVFAENETG 30512
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 316 DPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
DPP PP P + ++ +TSV L+W+ P GG K ++ I K G +
Sbjct: 13982 DPPW-----PPGKP--TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTD------ 14028
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
++ G+ T + L+ Y+F + AVN E S P V
Sbjct: 14029 -----EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGE-SEPSEPSDPVLCREKLY 14082
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV 494
PSP ++ ++N+ L W PE G I +Y V+ + + + + T
Sbjct: 14083 PPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 14142
Query: 495 TISSLKPDTIYVFQIRARTAAG 516
T++ L ++YVF++ A A G
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIG 14164
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 28/243 (11%)
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRN-VISNINETSVILDWSWPLDTGGRKD 356
+ G + EN++ A K P +++ P P N V +I +TSV+ W PLD GG +
Sbjct: 14775 DHGLYMIKVENDHGIA-KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 14833
Query: 357 VTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVS 416
+ + +++ + P+ ++ L + +VT L+ Y F + A N
Sbjct: 14834 INY---------TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN--- 14881
Query: 417 ELSSPPRQFAAVSITTNQAAP--SPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY 474
P + + + P +P I +D TS NS+ + W EP+ IL Y +
Sbjct: 14882 RFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS-NSMLVKWNEPKDNGSPILGY---W 14937
Query: 475 YEKQEQETSY------TILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
EK+E +++ ++L A NV L YVF++ A AAG G S + +T
Sbjct: 14938 LEKREVNSTHWSRVNKSLLNALKANV--DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKT 14995
Query: 529 SPD 531
+ D
Sbjct: 14996 AHD 14998
Score = 56.2 bits (134), Expect = 7e-08
Identities = 60/223 (26%), Positives = 88/223 (39%), Gaps = 19/223 (8%)
Query: 307 ENNYFRADKDPPSMACTRPPSSPRN-----VISNINETSVILDWSWPLDTGGRKDVTFNI 361
EN Y D A + P P VISNI + + + W P D GG +T
Sbjct: 19465 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGG-SPIT--- 19520
Query: 362 ICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
G+ +++ E + N + R+ + T+ T L T Y F + A+N P
Sbjct: 19521 -----GYLLEKRETQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGP-GKP 19573
Query: 422 PRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDY--EVKYYEKQ 478
A Q P P K T+R+S+SLSW +P + G I+ Y EVK +
Sbjct: 19574 SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSD 19633
Query: 479 EQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS 521
+ T ++ L DT Y F++ A GY S
Sbjct: 19634 NWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 19676
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/190 (25%), Positives = 89/190 (46%), Gaps = 22/190 (11%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S++ +TS + W+ P + GG + VT I+ K+ + K +P V+ T
Sbjct: 18707 VSDVTKTSCHVSWAPPENDGGSQ-VTHYIVEKREA-DRKTWSTVTPEVK---------KT 18755
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT+L+ Y F + AVN G + P+ A + + P P ++ ++
Sbjct: 18756 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA---SDPLSEPDPPRKLEVTEMTK 18812
Query: 451 NSISLSWQEPEHPNGIILDYEVKYYEKQEQE----TSYTILRARGTNVTISSLKPDTIYV 506
NS +L+W P G +D + Y ++EQ T Y+++ + ++ ++ LK Y
Sbjct: 18813 NSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV--KDLSLVVTGLKEGKKYK 18870
Query: 507 FQIRARTAAG 516
F++ AR A G
Sbjct: 18871 FRVAARNAVG 18880
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/222 (26%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L WS PL GG D++ ++ K+ W + E
Sbjct: 23721 PPEGPVQV-TGVTSEKCSLTWSPPLQDGG-SDISHYVVEKRETSRLAWTVVASE------ 23772
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ ++ VT LL Y F I AVN GV E P + A V + P
Sbjct: 23773 --------VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE----PLESAPVLMKNPFVLPG 23820
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTN 493
P +++ +++S+++ W P+ G I+ Y V EK+++ I R
Sbjct: 23821 PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV---EKRDRSGIRWIKCNKRRITDLR 23877
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYY 535
+ ++ L D Y F++ A AAG G E SP +YY
Sbjct: 23878 LRVTGLTEDHEYEFRVSAENAAGVG--------EPSPATVYY 23911
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 319 SMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSP 378
S PP P V + +I+ W+ P GG +++ ++ K+ E S
Sbjct: 29236 SFTIPSPPGIPEEV--GTGKEHIIIQWTKPESDGGN-EISNYLVDKR--------EKKSL 29284
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
+ + + + +T + VT L+ +Y F + AVN S P +S P
Sbjct: 29285 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN-SEPSEASNFISCREPSYTPG 29343
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE--TSYTILRARGTNVT 495
P + T+++SISL+W +P + G I+ Y ++ EK + +T R T T
Sbjct: 29344 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 29403
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
+ LK Y F++ A G
Sbjct: 29404 VPDLKMGQKYSFRVAAVNVKG 29424
Score = 55.5 bits (132), Expect = 1e-07
Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 29/237 (12%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTR-------PPSSPRNVISNINETSVILDWSW 347
+T E+ + EN + +D + + PPS+P ++N+ S+ + W
Sbjct: 26635 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPW--VTNVTRESITVGWHE 26692
Query: 348 PLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTF 407
P+ GG V +++ K + Q + + T VT + A Y F
Sbjct: 26693 PVSNGGSAVVGYHLEMKDRNSILWQ----------KANKLVIRTTHFKVTTISAGLIYEF 26742
Query: 408 EIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
+ A N GV + S P A+ A P ++ S+NS+SLSWQ+P G
Sbjct: 26743 RVYAENAAGVGKPSHPSEPVLAID------ACEPPRNVRITDISKNSVSLSWQQPAFDGG 26796
Query: 466 I-ILDYEVKYYEKQE-QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTN 520
I Y V+ + + + T + T IS L ++ Y F++ AR A G +N
Sbjct: 26797 SKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISN 26853
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 24/207 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P VIS+I E SV L W P GG + VT I+ K+ E + R
Sbjct: 26572 PPTGPV-VISDITEESVTLKWEPPKYDGGSQ-VTNYILLKRETSTAVWTEVSATVAR--- 26626
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
T + V L Y F I A N G+S+ A V++ P P T
Sbjct: 26627 -------TMMKVMKLTTGEEYQFRIKAENRFGISDHIDS----ACVTVKLPYTTPGPPST 26675
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R SI++ W EP G ++ Y ++ ++ Q+ + ++R T+ +++
Sbjct: 26676 PWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT--THFKVTT 26733
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFE 525
+ IY F++ A AAG G S E
Sbjct: 26734 ISAGLIYEFRVYAENAAGVGKPSHPSE 26760
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 24/196 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P N+ + ++ + S +L W P + GG ++I K W + C+
Sbjct: 26278 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW-VSVTNNCN---- 26332
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
+ VT+L Y F + N + P V IT PSP
Sbjct: 26333 ---------RLSYKVTNLQEGAIYYFRVSGENEFG-VGIPAETKEGVKITEK---PSPPE 26379
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ S++S+SL+W +PEH G I+ Y V+ EK Q+ A+ T+ +S L+
Sbjct: 26380 KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEK-GQKNWVKCAVAKSTHHVVSGLR 26438
Query: 501 PDTIYVFQIRARTAAG 516
++ Y F++ A AG
Sbjct: 26439 ENSEYFFRVFAENQAG 26454
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/193 (26%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ + + +TSV L W PL GG K N I +K K + N
Sbjct: 21952 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSK--IKNYIVEKRESTRKAYSTVATNCH--- 22006
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T+ V L +Y F + A N + P +V + P + +
Sbjct: 22007 ------KTSWKVDQLQEGCSYYFRVLAENEYG-IGLPAETAESVKASERPLPPGKITLMD 22059
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RNS+SLSW++PEH G IL Y V+ K + + T + T TI+ L
Sbjct: 22060 ---VTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA-TCATVKVTEATITGLIQGE 22115
Query: 504 IYVFQIRARTAAG 516
Y F++ A+ G
Sbjct: 22116 EYSFRVSAQNEKG 22128
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 26/197 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS P N+ ++ I + SV + W PL GG K N I +K K N
Sbjct: 23034 PSPPVNLKVTEITKDSVSITWEPPLLDGGSK--IKNYIVEKREATRKSYAAVVTNCH--- 23088
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN----GVSELSSPPRQFAAVSITTNQAAPSPV 440
+ + L +Y F + A N G+ ++ P + A V P P
Sbjct: 23089 ------KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV--------PQPP 23134
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSL 499
I D +RNS+SLSW +PEH G I+ Y V+ K ++ S R + I++L
Sbjct: 23135 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWS-ECARVKSLQAVITNL 23193
Query: 500 KPDTIYVFQIRARTAAG 516
Y+F++ A G
Sbjct: 23194 TQGEEYLFRVVAVNEKG 23210
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/202 (26%), Positives = 93/202 (46%), Gaps = 26/202 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PP P +SN+ + + + W P+D GG ++T G+++++ E S VR +
Sbjct: 20574 PPEKPE--VSNVTKNTATVSWKRPVDDGG-SEIT--------GYHVERREKKSLRWVRAI 20622
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA--PSPVL 441
+ +++ VT L + Y F + A N PP + A+ S+ AA P P
Sbjct: 20623 --KTPVSDLRCKVTGLQEGSTYEFRVSAENRAG--IGPPSE-ASDSVLMKDAAYPPGPPS 20677
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ----ETSYTILRARGTNVTI 496
T++ S SL+W +P + G+ I Y V++ + ++ +T+ T LR T +
Sbjct: 20678 NPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI--TQFVV 20735
Query: 497 SSLKPDTIYVFQIRARTAAGYG 518
L+ Y F+I A AG G
Sbjct: 20736 PDLQTKEKYNFRISAINDAGVG 20757
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P VI N+ + L W P+ GG + F++ K+ + Q SP
Sbjct: 27759 PPGKP--VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSP------ 27810
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
++ T L+ +Y F + A N G+S S P + AVS P +
Sbjct: 27811 ----ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI-- 27864
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+R +I+L W P G I+ Y ++ + E+ T++ L P
Sbjct: 27865 ----DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSP 27920
Query: 502 DTIYVFQIRARTAAG 516
Y F+I AR A G
Sbjct: 27921 GDRYEFRIIARNAVG 27935
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P N+ I + + SV L W PL GG K N I +K K + N
Sbjct: 25199 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKIT--NYIVEKRETTRKAYATITNNC---- 25252
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T TT + +L +Y F + A N + P V ++ P V +
Sbjct: 25253 -----TKTTFRIENLQEGCSYYFRVLASNEYG-IGLPAETTEPVKVSEPPLPPGRVTLVD 25306
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RN+ ++ W++PE G I Y V+ K ++ S T + + TIS L
Sbjct: 25307 ---VTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-TCTQVKTLEATISGLTAGE 25362
Query: 504 IYVFQIRARTAAG 516
YVF++ A G
Sbjct: 25363 EYVFRVAAVNEKG 25375
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/217 (24%), Positives = 85/217 (39%), Gaps = 39/217 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP+ P I+ + L W P + GG D+ + I+ K+ W I + E
Sbjct: 25885 PPAGPLE-INGLTAEKCSLSWGRPQEDGGA-DIDYYIVEKRETSHLAWTICEGE------ 25936
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L T+ VT LL Y F + VN GV E P + A+ PS
Sbjct: 25937 --------LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE----PLESVAIKALDPFTVPS 25984
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRAR-----GTN 493
P +++ ++ S++L W PE G + Y ++ ++ S +R
Sbjct: 25985 PPTSLEITSVTKESMTLCWSRPESDGGSEIS---GYIIERREKNSLRWVRVNKKPVYDLR 26041
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
V + L+ Y +++ A AAG S ETSP
Sbjct: 26042 VKSTGLREGCEYEYRVYAENAAGLSLPS-----ETSP 26073
Score = 49.3 bits (116), Expect = 9e-06
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S+++ S +L W P D GG + + + ++ G Q S + T
Sbjct: 28750 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-----------VKRT 28798
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT L + Y+F + + N GVS+ P + A + PS + S
Sbjct: 28799 QIKVTHLTKYMEYSFRVSSENRFGVSK----PLESAPIIAEHPFVPPSAPTRPEVYHVSA 28854
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRAR----GTNVTISSLKPDTIY 505
N++S+ W+EP H G I+ Y + EK+E+ T + + N ++ L Y
Sbjct: 28855 NAMSIRWEEPYHDGGSKIIGY---WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEY 28911
Query: 506 VFQIRARTAAG 516
F+ A AAG
Sbjct: 28912 QFRTYALNAAG 28922
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 20/201 (9%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL- 383
P + + +S++ S+ ++W P GG VT G+ ++ + S + +
Sbjct: 16317 PGAPDKPTVSSVTRNSMTVNWEEPEYDGG-SPVT--------GYWLEMKDTTSKRWKRVN 16367
Query: 384 --PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
P + + VT L+ ++Y F + A+N GV S P A P P
Sbjct: 16368 RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP 16427
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSY-TILRARGTNVTIS 497
+T +++S L W P G + Y V+Y E+ ++E RGT + ++
Sbjct: 16428 KVT----DWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 16483
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
LK Y F++RA AG G
Sbjct: 16484 GLKEGAFYKFRVRAVNIAGIG 16504
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + IS+I+ + L W PL+ GG ++T N I +KC ++ + + ++
Sbjct: 18994 PPQPPFD-ISDIDADACSLSWHIPLEDGG-SNIT-NYIVEKC--DVSRGD-------WVT 19041
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T T+ V L+ Y F + A N G+SE + P+ A PS
Sbjct: 19042 ALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF----GVPSEPKN 19097
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRA-----RGTNVTIS 497
+ + +++ I ++W P+ G + + Y ++++ S ++A R T +
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPI---IGYLIERKERNSLLWVKANDTLVRSTEYPCA 19154
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETS 529
L Y F+I A AG S+ E+ T+
Sbjct: 19155 GLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA 19186
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICK-KCGWNIKQCEPCSPNVRF 382
PP P+N ++ I + S+++ W P GG + + + + + K G +C +
Sbjct: 21654 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT----- 21708
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ V+ L Y F I A N +S+P P P
Sbjct: 21709 ------LTDLRYKVSGLTEGHEYEFRIMAENAAG-ISAPSPTSPFYKACDTVFKPGPPGN 21761
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSL 499
+ TSR+SIS++W +P + G I Y V+ +E E A + T+ TI+ L
Sbjct: 21762 PRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGL 21821
Query: 500 KPDTIYVFQIRARTAAGYG 518
+ Y +I A + G G
Sbjct: 21822 TENQEYKIRIYAMNSEGLG 21840
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 26/210 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIK--QCEPCSPN 379
P RN+ ++ + V L W PL GG K + + + K+ W + + E C
Sbjct: 13090 PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 13149
Query: 380 VRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP 439
V L + Y F + A N V P V + P P
Sbjct: 13150 VTGLQK---------------GGVEYLFRVSARNRVGT-GEPVETDNPVEARSKYDVPGP 13193
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQ--EQETSYTILRARGTNVTI 496
L + +R +SL+W+ PE+ G I +Y ++ +K +T+ T+ RA + T+
Sbjct: 13194 PLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTV-RAEDLSATV 13252
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+ + Y F++RA+ G G S F
Sbjct: 13253 TDVVEGQEYSFRVRAQNRIGVGKPSAATPF 13282
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/261 (23%), Positives = 95/261 (36%), Gaps = 38/261 (14%)
Query: 287 CAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP--PSSPRNVISNINETSVILD 344
C P S + G NN A K+ RP P P +++ + L
Sbjct: 16179 CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIK-FESVSADQMTLS 16237
Query: 345 WSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLA 401
W P D GG K + I ++ W EP T T+ LL
Sbjct: 16238 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP--------------KECTYTIPKLLE 16283
Query: 402 HTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQE 459
Y F I A N G+ E + A + A P ++ +RNS++++W+E
Sbjct: 16284 GHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVS----SVTRNSMTVNWEE 16339
Query: 460 PEHPNGIILDYEVKYYEKQEQETSYTILRAR---------GTNVTISSLKPDTIYVFQIR 510
PE+ G + Y+ + + TS R G + ++ L + Y F++
Sbjct: 16340 PEYDGGSPV---TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVY 16396
Query: 511 ARTAAGYGTNSRKFEFETSPD 531
A AAG G S + T+ D
Sbjct: 16397 AINAAGVGPASLPSDPATARD 16417
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/199 (24%), Positives = 89/199 (44%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P +++I++ +++ W P++ GG K + G++++Q E S L
Sbjct: 24507 PPGTP--FVTSISKDQMLVQWHEPVNDGGTKII---------GYHLEQKEKNSILWVKLN 24555
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T T L Y F++ A N G+ + S F A P ++
Sbjct: 24556 KT-PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 24614
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RN+++L W++P + G + Y +++ ++A TNV T+S
Sbjct: 24615 ------TRNNVTLKWKKPAYDGGSKI---TGYIVEKKDLPDGRWMKASFTNVLETEFTVS 24665
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ AR AAG
Sbjct: 24666 GLVEDQRYEFRVIARNAAG 24684
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 15/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PS P ++ I+++ + S+ L WS P GG + G+ I++ E S VR
Sbjct: 25983 PSPPTSLEITSVTKESMTLCWSRPESDGGSEI---------SGYIIERREKNSLRWVRVN 26033
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + V T L Y + + A N LS P + PSP
Sbjct: 26034 KKP--VYDLRVKSTGLREGCEYEYRVYAENAAG-LSLPSETSPLIRAEDPVFLPSPPSKP 26090
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
K + + +I+++W +P G I Y V+Y + + + +I RGT TIS L
Sbjct: 26091 KIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTG 26150
Query: 503 TIYVFQIRARTAAG 516
YVF++++ G
Sbjct: 26151 AEYVFRVKSVNKVG 26164
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 29/222 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS PRN+ +++I S L W PLD GG ++T +I K+ + K+ E +
Sbjct: 15498 PSPPRNLAVTDIKAESCYLTWDAPLDNGG-SEITHYVIDKRDA-SRKKAEWEEVTNTAVE 15555
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+++G + L+ + Y F + AVN G+S+ + V I P P
Sbjct: 15556 KRYG-------IWKLIPNGQYEFRVRAVNKYGISDECKSDK----VVIQDPYRLPGPPGK 15604
Query: 443 IKKDRTSRNSISLSWQEP-EHPNGIILDYEVKYYEKQEQETSY---------TILRARGT 492
K ++ S+ +SW P ++ I Y + EK+E+ + Y T + +G
Sbjct: 15605 PKVLARTKGSMLVSWTPPLDNGGSPITGY---WLEKREEGSPYWSRVSRAPITKVGLKGV 15661
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L Y F+ A AAG G S + E + D ++
Sbjct: 15662 EFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIF 15703
Score = 47.8 bits (112), Expect = 3e-05
Identities = 53/254 (20%), Positives = 92/254 (36%), Gaps = 38/254 (14%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+T++D N F + + P P V ISN++ L W+ PL+ GG
Sbjct: 20442 ATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGG 20501
Query: 354 --------RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNY 405
K T ++ +I+ C T L+ Y
Sbjct: 20502 SPIKSYILEKRETSRLLWTVVSEDIQSCRH-------------------VATKLIQGNEY 20542
Query: 406 TFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
F + AVN + P Q V + P P + ++N+ ++SW+ P G
Sbjct: 20543 IFRVSAVNHYGK--GEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGG 20600
Query: 466 IILDYEVKYYEKQEQETSYTILRARGTNVT-----ISSLKPDTIYVFQIRARTAAGYGTN 520
+ Y+ ++ ++ S +RA T V+ ++ L+ + Y F++ A AG G
Sbjct: 20601 SEI---TGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPP 20657
Query: 521 SRKFEFETSPDCMY 534
S + D Y
Sbjct: 20658 SEASDSVLMKDAAY 20671
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/198 (22%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICK---KCGWNIKQCEPCSPNVR 381
P + + + +++ +V L W PL GG + + I + K W++ CS
Sbjct: 27366 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVS-HKCS---- 27420
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
+T+ + DL T + F + A N G+ E A + P+P
Sbjct: 27421 ---------STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV------PAP 27465
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
+ + +++ S+ LSW +P+ G +I +Y V+ K EQ S+ + ++ + +S
Sbjct: 27466 IRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI-SKTCEIEVSQ 27524
Query: 499 LKPDTIYVFQIRARTAAG 516
LK ++ F++ A+ G
Sbjct: 27525 LKEQSVLEFRVFAKNEKG 27542
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P + P I ++ SV L W+ P TGG +++ K+ + + +P +R
Sbjct: 20176 PDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTP-IRM-- 20232
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
R F VT L Y F + A+N GV + S P A+ P +
Sbjct: 20233 RDF-------KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVI-- 20283
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RNS++L W EP++ G L Y ++ S + ++A NV T++
Sbjct: 20284 ----NITRNSVTLIWTEPKYDGGHKL---TGYIVEKRDLPSKSWMKANHVNVPECAFTVT 20336
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+IRA+ AG
Sbjct: 20337 DLVEGGKYEFRIRAKNTAG 20355
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 25/200 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
I+++ S +L W+ P D GG K N + ++ + + S V+ +T
Sbjct: 13792 ITDVTNESCLLTWNPPRDDGGSK--ITNYVVERRATDSEVWHKLSSTVK---------DT 13840
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
T L+ + Y F + A N GV E P Q + ++ P P ++ ++
Sbjct: 13841 NFKATKLIPNKEYIFRVAAENMYGVGE----PVQASPITAKYQFDPPGPPTRLEPSDITK 13896
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTNVTISSLKPDTIY 505
++++L+W EP+ G I Y + E+ + +T + + + T + L Y
Sbjct: 13897 DAVTLTWCEPDDDGGSPITGY---WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKY 13953
Query: 506 VFQIRARTAAGYGTNSRKFE 525
F++ A AG G S+ E
Sbjct: 13954 RFRVLAENLAGPGKPSKSTE 13973
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ ++ + + S+ + W PL GG + +++ K+ + Q + +
Sbjct: 21261 PPGTPQ--VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 21318
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ GLT+ Y F + A N G S+ S P A+ P P+
Sbjct: 21319 KSSGLTDGIA----------YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL-- 21366
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+R++++L W +PE+ G + Y ++ + L+A +N+ T+S
Sbjct: 21367 ----NITRHTVTLKWAKPEYTGGFKI---TSYIVEKRDLPNGRWLKANFSNILENEFTVS 21419
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 21420 GLTEDAAYEFRVIAKNAAG 21438
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 42/225 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L W+ PL GG +++ II K+ W E + N
Sbjct: 24804 PPEGPLKV-TGVTAEKCYLAWNPPLQDGGA-NISHYIIEKRETSRLSWTQVSTEVQALNY 24861
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ VT LL Y F + AVN G+ E P + V+ P
Sbjct: 24862 K--------------VTKLLPGNEYIFRVMAVNKYGIGE----PLESGPVTACNPYKPPG 24903
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQE---------TSYTILRA 489
P T + +++S+ ++W P G + E EK+++E + T LR
Sbjct: 24904 PPSTPEVSAITKDSMVVTWARPVDDGGT--EIEGYILEKRDKEGVRWTKCNKKTLTDLRL 24961
Query: 490 RGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
R T +T Y F++ A AAG G S F + D +Y
Sbjct: 24962 RVTGLTEGHS-----YEFRVAAENAAGVGEPSEPSVFYRACDALY 25001
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 31/191 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNI-----ICKKCGWNIKQCEPCSPNVRFLPRQFG 388
++I + SV L W PL GG + + + K +C C
Sbjct: 20877 TDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC------------ 20924
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKD 446
T VT L Y F + A N G+ E + A APSP ++
Sbjct: 20925 ----TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA------SEAPSPPDSLNIM 20974
Query: 447 RTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
+++++SL+W +P+H G I Y ++ K + ++ I +G + +L Y
Sbjct: 20975 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTH-ITTVKGLECVVRNLTEGEEY 21033
Query: 506 VFQIRARTAAG 516
FQ+ A +AG
Sbjct: 21034 TFQVMAVNSAG 21044
Score = 46.2 bits (108), Expect = 8e-05
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 30/219 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ + +L W PLD GG K + I+ K+ + S
Sbjct: 21557 PPEGPL-AVTEVTSEKCVLSWFPPLDDGGAK-IDHYIVQKRETSRLAWTNVASE------ 21608
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T + VT LL Y F + AVN GV E P + V P P
Sbjct: 21609 ----VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE----PLESEPVLAVNPYGPPDPPKN 21660
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVT 495
+ +++S+ + W P+ G I++Y V+ +K Q + + T LR +
Sbjct: 21661 PEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYK----- 21715
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+S L Y F+I A AAG S F + D ++
Sbjct: 21716 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 21754
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 24/213 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + L W P D GG K +T I+ K+ + V +
Sbjct: 26968 PPGGPIE-FKTVTAEKITLLWRPPADDGGAK-ITHYIVEKRE----------TSRVVWSM 27015
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
L +T T ++ Y F + AVN G+ E P + +V P P
Sbjct: 27016 VSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE----PLESDSVVAKNAFVTPGPPGI 27071
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS--YTILR--ARGTNVTISS 498
+ + ++NS+++ W P G D + EK+++++ + +L+ R T ++
Sbjct: 27072 PEVTKITKNSMTVVWSRPIADGG--SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTG 27129
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
L ++ Y +++ A AAG G S EF + D
Sbjct: 27130 LTENSDYQYRVCAVNAAGQGPFSEPSEFYKAAD 27162
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
T V DL Y F + AVN GV E P + + T Q AP L +
Sbjct: 28503 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGE----PYEMPEPIVATEQPAPPRRLDVVD-- 28556
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ---ETSYTILRARGTNVTISSLKPDT 503
TS++S L+W +P+H G I Y ++ +K E +T + T+ L T
Sbjct: 28557 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT----KQLTFTVERLVEKT 28612
Query: 504 IYVFQIRARTAAGYGTNSRKF 524
Y F+++A+ AGY F
Sbjct: 28613 EYEFRVKAKNDAGYSEPREAF 28633
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 26/245 (10%)
Query: 298 EDGSMNCRCENNYFRADKDPPS--MACTR---PPSSPRNV-ISNINETSVILDWSWPLDT 351
++ S R N ++ PS + C PPS PR + + NI + + L W+ P
Sbjct: 14051 QEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKD 14110
Query: 352 GGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDA 411
GG +T N I +K K + V+ +T TVT L + Y F + A
Sbjct: 14111 GG-SPIT-NYIVEKRDVRRKGWQTVDTTVK---------DTKCTVTPLTEGSLYVFRVAA 14159
Query: 412 VNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYE 471
N + + + + ++ T P D T R+ + L W+ P++ G +
Sbjct: 14160 ENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQ-- 14216
Query: 472 VKYYEKQEQETSYTILRARGT-----NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+Y ++++ ++A T N ++ + T FQ+RA AG G S E
Sbjct: 14217 -RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEI 14275
Query: 527 ETSPD 531
+ D
Sbjct: 14276 LSIED 14280
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/212 (26%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNVRFLPRQFGL 389
+ ++ + V L W P + GGR + I K+ W +K + P+ F
Sbjct: 14192 VVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW-VKAGKTAGPDCNF------- 14243
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
VTD++ T F++ A N GV S P +SI + PSP L +
Sbjct: 14244 -----RVTDVIEGTEVQFQVRAENEAGVGHPSEPTE---ILSIEDPTSPPSPPLDLHVTD 14295
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKY----YEKQEQETSYTILRARGTNVTISSLKPD 502
R I+++W+ PE G I+ Y V+ EK + S I + + PD
Sbjct: 14296 AGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFK--VEEGVVPD 14353
Query: 503 TIYVFQIRARTAAGYGTNSRKFE--FETSPDC 532
YV ++RA A G S E PDC
Sbjct: 14354 KEYVLRVRAVNAIGVSEPSEISENVVAKDPDC 14385
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 28/218 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP P VIS + L W PL GG + + + ++ W + NV+
Sbjct: 22639 PPEGPV-VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA-----NVQ 22692
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSE-LSSPPRQFAAVSITTNQAAPS 438
L + VT LL YTF I AVN GV E L S P + +
Sbjct: 22693 TL---------SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 22743
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG-TNVTI 496
V T+ KD S+ + W+ P G IL Y ++ +K+ + R G + +
Sbjct: 22744 EVTTVTKD-----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 22798
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++ A AAG S ++ + D +Y
Sbjct: 22799 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 22836
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 21/134 (15%)
Query: 299 DGSMNCRCENNYFRADKDPPSM---ACTR-----PPSSPRNVISNINETSVILDWSWPLD 350
D EN ++ PPS AC PP++P+ + +I +SV L WS P+
Sbjct: 22806 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPK--VIDITRSSVFLSWSKPIY 22863
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG + + I +KC ++ + C+P G+ T + V LL Y F I
Sbjct: 22864 DGGCEIQGY--IVEKCDVSVGEWTMCTPPT-------GINKTNIEVEKLLEKHEYNFRIC 22914
Query: 411 AVN--GVSELSSPP 422
A+N GV E + P
Sbjct: 22915 AINKAGVGEHADVP 22928
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 23/201 (11%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ ++NI + S+ + W+ P D+ G ++ I+ K+ I+ + C+
Sbjct: 23819 PGPPKSLEVTNIAKDSMTVCWNRP-DSDGGSEIIGYIVEKRDRSGIRWIK-CNKR----- 23871
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T+ + VT L Y F + A N GV E S + A P+
Sbjct: 23872 ---RITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 23928
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE----TSYTILRARGTNVTIS 497
+ T++NSI+L+W +P + G IL Y V+ + E+E T T LR T IS
Sbjct: 23929 VD---TTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRV--TRFEIS 23983
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y ++ A G G
Sbjct: 23984 KLTEHQEYKIRVCALNKVGLG 24004
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 292 PHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLD 350
P+ ++D C N F D+ + P PR V +S+++ SV L W+ P
Sbjct: 31088 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPAS 31147
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG K N I +KC + R+L R T TV +L T+Y F +
Sbjct: 31148 DGGSK--ITNYIVEKCATTAE---------RWL-RVGQARETRYTVINLFGKTSYQFRVI 31195
Query: 411 AVN--GVSELSSP 421
A N G+S+ S P
Sbjct: 31196 AENKFGLSKPSEP 31208
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P PR++ +S I + S L W PLD GG V N + ++ Q P
Sbjct: 17310 PGPPRDLEVSEIRKDSCYLTWKEPLDDGG--SVITNYVVERRDVASAQWSP--------- 17358
Query: 385 RQFGLTNTTVTVTDLLAHTN----YTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L+ T+ + H N Y F + A N G P+ A+ P
Sbjct: 17359 ----LSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPK 17414
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV--T 495
+ + D+T +SL W +P+ G I Y V+Y QE+ T I TN+
Sbjct: 17415 DLHHVDVDKTE---VSLVWNKPDRDGGSPITGYLVEY---QEEGTQDWIKFKTVTNLECV 17468
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L+ Y F+++A G G
Sbjct: 17469 VTGLQQGKTYRFRVKAENIVGLG 17491
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 26/204 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P RN+ I +++ + W P D GG C+ + +++CE R +
Sbjct: 18297 PGPVRNLKIVDVSSDRCTVCWDPPEDDGG---------CEIQNYILEKCE----TKRMVW 18343
Query: 385 RQFGLTNTT--VTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T T TVT L+ Y F + A N + + PP + V T P
Sbjct: 18344 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG--TGPPTESKPVIAKTKYDKPGRPDP 18401
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGT----NVTIS 497
+ + S+ +++ W PE+ G I Y + EK+E+ ++ + + + +
Sbjct: 18402 PEVTKVSKEEMTVVWNPPEYDGGKSITGY---FLEKKEKHSTRWVPVNKSAIPERRMKVQ 18458
Query: 498 SLKPDTIYVFQIRARTAAGYGTNS 521
+L PD Y F+++A G G S
Sbjct: 18459 NLLPDHEYQFRVKAENEIGIGEPS 18482
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/209 (25%), Positives = 84/209 (40%), Gaps = 33/209 (15%)
Query: 326 PSSPRNVIS--NINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P+SP + +I SV + W P D GG + G+ +++ E P +
Sbjct: 30228 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL---------GYILERREV--PKAAWY 30276
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP---- 439
+ T++ V L + Y F + A N +S P + V+ T P P
Sbjct: 30277 TIDSRVRGTSLVVKGLKENVEYHFRVSAENQFG-ISKPLKSEEPVTPKTPLNPPEPPSNP 30335
Query: 440 --VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG----T 492
VL + K +S+SLSW P+ G + Y Y E++E T + + T
Sbjct: 30336 PEVLDVTK-----SSVSLSWSRPKDDGGSRVTGY---YIERKETSTDKWVRHNKTQITTT 30387
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNS 521
T++ L PD Y F+I A+ G S
Sbjct: 30388 MYTVTGLVPDAEYQFRIIAQNDVGLSETS 30416
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/201 (23%), Positives = 82/201 (40%), Gaps = 34/201 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
S+I ++S L W P GG + + + ++ G ++P G +
Sbjct: 14489 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRT-----------YIPVMSGENKLS 14537
Query: 394 VTVTDLLAHTNYTFEIDAVNGVS-----ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
TV DL+ + Y F + AVN V EL +P V + P P + ++
Sbjct: 14538 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP------VIAQDPKQPPDPPVDVEVHNP 14591
Query: 449 SRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVTISSLKP 501
+ +++++W+ P + G I+ Y ++ K E+ E IL T L+
Sbjct: 14592 TAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL-----TYTAKGLEE 14646
Query: 502 DTIYVFQIRARTAAGYGTNSR 522
Y F++RA AAG SR
Sbjct: 14647 GKEYQFRVRAENAAGISEPSR 14667
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/201 (22%), Positives = 80/201 (39%), Gaps = 25/201 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P NV + I++ S + W P+ GG + + + ++ W+ E CS
Sbjct: 19787 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CS---- 19841
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
T+ V +L +Y F + A N + P AV + P PV+
Sbjct: 19842 ---------KTSFRVANLEEGKSYFFRVFAENEYG-IGDPGETRDAVKASQT---PGPVV 19888
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+K S++S S+ W++P G I+ Y V + E+ ++++ + L
Sbjct: 19889 DLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLT 19946
Query: 501 PDTIYVFQIRARTAAGYGTNS 521
Y F++ A G GT S
Sbjct: 19947 EGKEYTFRVSAENENGEGTPS 19967
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + I++ S+++ W P++ GG + G+++++ E S +
Sbjct: 23425 PPGTP--FATAISKDSMVIQWHEPVNNGGSPVI---------GYHLERKERNSILWTKVN 23473
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T +L Y F + A N GV + S + A P P++
Sbjct: 23474 KTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMV 23532
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
RN I+L W +P + G ++ Y ++ ++A TNV T+S
Sbjct: 23533 ------KRNEITLQWTKPVYDGGSMI---TGYIVEKRDLPDGRWMKASFTNVIETQFTVS 23583
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 23584 GLTEDQRYEFRVIAKNAAG 23602
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P+ + +I + SV L W P D GG +T ++ K+ S
Sbjct: 13488 PSAPKELKFGDITKDSVHLTWEPPDDDGG-SPLTGYVVEKR---------EVSRKTWTKV 13537
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
F +T+ TV DL+ Y F++ A N P V+++T P P +K
Sbjct: 13538 MDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGP-GEPAYVDEPVNMSTPATVPDPPENVK 13595
Query: 445 -KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+DRT+ NSI L+W P++ G I Y V+ + + T + ++ L+
Sbjct: 13596 WRDRTA-NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEG 13654
Query: 503 TIYVFQIRARTAAGYGTNSRKFE 525
Y ++++A G SR E
Sbjct: 13655 KWYAYRVKALNRQGASKPSRPTE 13677
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ +S+I S L W P D GG D + +K + K +P+
Sbjct: 15912 PGPPKDLKVSDITRGSCRLSWKMPDDDGG--DRIKGYVIEKRTIDGKAWTKVNPDCG--- 15966
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+TT V DLL+ Y F + A N + P + P P + +K
Sbjct: 15967 ------STTFVVPDLLSEQQYFFRVRAENRFG-IGPPVETIQRTTARDPIYPPDPPIKLK 16019
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYY------EKQEQETSYTILRARGTNVTIS 497
++N++ LSW+ P++ G + Y V+ K+E T+
Sbjct: 16020 IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 16079
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+++A AAG
Sbjct: 16080 DLVEGGEYEFRVKAVNAAG 16098
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 32/201 (15%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP +P V++ + S+ + W+ P+ GG + + +++ K+ W +K + P +
Sbjct: 22343 PPGTP--VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTK 22399
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
F T L Y F + A N G+ + S + A P
Sbjct: 22400 F------------KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEA 22447
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVT 495
++ +RNS++L W++P + G I Y V+ E E + S+T T+
Sbjct: 22448 IIV------TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT--NIIDTHFE 22499
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
++ L D Y F++ AR AAG
Sbjct: 22500 VTGLVEDHRYEFRVIARNAAG 22520
Score = 43.9 bits (102), Expect = 4e-04
Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ S+ L W+ PL TGG + N I +K + S V
Sbjct: 23325 PPKGPVK-FDDVSAESITLSWNPPLYTGGCQ--ITNYIVQKRDTTTTVWDVVSATV---- 23377
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE---LSSPPRQFAAVSITTNQAAPSPVL 441
TT+ VT L T Y F I A N + L S P + P P
Sbjct: 23378 -----ARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP-----IVAQYPYKEPGPPG 23427
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTIS 497
T S++S+ + W EP + G ++ Y ++ E+ + + TI+ T
Sbjct: 23428 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII--HDTQFKAQ 23485
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+L+ Y F++ A G G S+ E + D
Sbjct: 23486 NLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 23519
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/193 (23%), Positives = 76/193 (39%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+N+ + + + S L W P+ GG K + I ++ S +
Sbjct: 24116 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----------STRKAYAN 24164
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T+ V +L Y F + A N + P AV PSP +
Sbjct: 24165 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-VGVPVETVDAVKAAE---PPSPPGKVT 24220
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
S+ S SL W++PEH G +L Y V+ K ++ S + ++ N ++ L
Sbjct: 24221 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS-IVAESKVCNAVVTGLSSGQ 24279
Query: 504 IYVFQIRARTAAG 516
Y F+++A G
Sbjct: 24280 EYQFRVKAYNEKG 24292
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/206 (21%), Positives = 81/206 (39%), Gaps = 22/206 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ V++ W P TGG C+ + +++ + + +
Sbjct: 24407 PPVGPVR-FDEVSADFVVISWEPPAYTGG---------CQISNYIVEKRDTTTTTWHMVS 24456
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TT+ +T L T Y F I A N + S P AV + P P T
Sbjct: 24457 AT--VARTTIKITKLKTGTEYQFRIFAENRYGK--SAPLDSKAVIVQYPFKEPGPPGTPF 24512
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTI 504
S++ + + W EP + G + + Y+ +Q+++ S ++ T + + K +
Sbjct: 24513 VTSISKDQMLVQWHEPVNDGGTKI---IGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGL 24569
Query: 505 -----YVFQIRARTAAGYGTNSRKFE 525
Y F++ A G G S+ E
Sbjct: 24570 DEGLEYEFKVSAENIVGIGKPSKVSE 24595
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/235 (20%), Positives = 100/235 (42%), Gaps = 18/235 (7%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+++ED C +N + P ++ P P + I ++ S+ + W+ P GG
Sbjct: 25457 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGG 25516
Query: 354 RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
C+ + +++ E S + + + T++ + L + Y F + A N
Sbjct: 25517 ---------CQISNYIVEKKETTSTTWHIVSQ--AVARTSIKIVRLTTGSEYQFRVCAEN 25565
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEV 472
+ S + +AV + P P T K +++++ ++WQ P + G ++ Y +
Sbjct: 25566 RYGKSSYS--ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL 25623
Query: 473 KYYEKQE--QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+Y E+ + IL A T + +S L +Y +++ A AG G S+ E
Sbjct: 25624 EYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE 25677
Score = 43.9 bits (102), Expect = 4e-04
Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 317 PPSMACTRPPSSPRNVI--SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCE 374
P ++ PPS P+ I I SVIL W P D GG + I C ++I++ E
Sbjct: 27648 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE-----ITC----YSIEKRE 27698
Query: 375 PCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITT 432
N + + + TT V +L+ Y F + A N GVS+ P + +
Sbjct: 27699 TSQTNWKMVCS--SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ----PLVSSIIVAKH 27752
Query: 433 NQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILR 488
P P + + +SL+W P + G + + V+ E+ Q+ + + +
Sbjct: 27753 QFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 27812
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS--RKFEFETSP 530
R T L Y F++ A +AG + S KF SP
Sbjct: 27813 GREYRAT--GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 27854
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 30/207 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P I I+ TS+ + W P GG G+ ++Q + P +LP
Sbjct: 29834 PPTGPIK-IDEIDATSITISWEPPELDGG---------APLSGYVVEQRDAHRPG--WLP 29881
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T +T T L Y F + A N G+ Q + ++ P P T
Sbjct: 29882 VSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSIRIPGPPET 29937
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE------QETSYTILRARGTNVT 495
++ SR+ ++L+W PE G + Y V+ E + + T+ R R T +T
Sbjct: 29938 LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLT 29997
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSR 522
Y ++ A A G G SR
Sbjct: 29998 -----EGLEYEHRVTAINARGSGKPSR 30019
Score = 43.1 bits (100), Expect = 6e-04
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P NV I+++N V L W P GG ++T +I + +I+ + L
Sbjct: 13191 PGPPLNVTITDVNRFGVSLTWEPPEYDGGA-EITNYVIELRDKTSIRWDTAMTVRAEDL- 13248
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TVTD++ Y+F + A N + + P V + PSP + +
Sbjct: 13249 --------SATVTDVVEGQEYSFRVRAQNRIG-VGKPSAATPFVKVADPIERPSPPVNLT 13299
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEK-QEQETSYTILRARGTNVTISSLKPD 502
+++S+ L W+ P G IL Y ++ E+ ++ + ++ L+
Sbjct: 13300 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 13359
Query: 503 TIYVFQIRARTAAG 516
Y++++ A AG
Sbjct: 13360 NKYLYRVSAENKAG 13373
Score = 43.1 bits (100), Expect = 6e-04
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 17/97 (17%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNI-ICKKC--GWNIKQCEPCSPNV 380
PP P V +++ ++T+V L+WS P+ GG + + + I +CK W+ E C
Sbjct: 28253 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC---- 28308
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE 417
T TVTDL A Y F + A+NG +
Sbjct: 28309 ---------VKTRYTVTDLQAGEEYKFRVSAINGAGK 28336
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + + +++ W PLD GG K + I K+ G ++ ++P
Sbjct: 16914 PPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDV-----------WMP 16961
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT V+ LL +Y F I A N G+S+ A A P++T
Sbjct: 16962 VTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVT 17021
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W +P I +Y EK+E + R VT + P
Sbjct: 17022 ----EVTKDSALVTWNKPHDGGKPITNY---ILEKRE------TMSKRWARVTKDPIHPY 17068
Query: 503 T-----------IYVFQIRARTAAGYGTNS 521
T Y F++ A G G S
Sbjct: 17069 TKFRVPDLLEGCQYEFRVSAENEIGIGDPS 17098
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 30/204 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNII----CKKCGWNIKQCEPCSPNVRFLPRQFG 388
+S + + L WS P + GG ++T I+ + W I + E P + ++
Sbjct: 29149 VSRVTQEKCTLAWSLPQEDGG-AEITHYIVERRETSRLNWVIVEGE--CPTLSYV----- 29200
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
VT L+ + Y F + AVN P + + + PSP ++ T
Sbjct: 29201 -------VTRLIKNNEYIFRVRAVNKYG--PGVPVESEPIVARNSFTIPSPPGIPEEVGT 29251
Query: 449 SRNSISLSWQEPEHPNG-IILDYEVKYYEKQ-----EQETSYTILRARGTNVTISSLKPD 502
+ I + W +PE G I +Y V EK+ Y + T + ++SL
Sbjct: 29252 GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVY---DTRLKVTSLMEG 29308
Query: 503 TIYVFQIRARTAAGYGTNSRKFEF 526
Y F++ A AAG S F
Sbjct: 29309 CDYQFRVTAVNAAGNSEPSEASNF 29332
Score = 40.4 bits (93), Expect = 0.004
Identities = 47/205 (22%), Positives = 82/205 (40%), Gaps = 34/205 (16%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNV 380
PPS+P R + +++ ++ + W P GG K + + + K+ W + PC
Sbjct: 28840 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC---- 28895
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
VT L+ Y F A+N GVS+ S R A + P
Sbjct: 28896 ---------LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE 28946
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARG 491
+R+++SL W P + G ++ Y ++ E + +YTI+
Sbjct: 28947 VT------DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS--D 28998
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T+++L Y F++ A+ AAG
Sbjct: 28999 NFFTVTALSEGDTYEFRVLAKNAAG 29023
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 16/189 (8%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
SNI S+ L W+ P GG + + + ++ + + V+ + ++ ++ T
Sbjct: 28161 SNITGNSITLTWARPESDGGSEIQQYILERRE--------KKSTRWVKVISKR-PISETR 28211
Query: 394 VTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
VT L Y F + A N GV S R + P P +K TS+
Sbjct: 28212 FKVTGLTEGNEYEFHVMAENAAGVGPASGISR---LIKCREPVNPPGPPTVVKVTDTSKT 28268
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTISSLKPDTIYVFQI 509
++SL W +P G+ I+ Y ++ + + A T T++ L+ Y F++
Sbjct: 28269 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 28328
Query: 510 RARTAAGYG 518
A AG G
Sbjct: 28329 SAINGAGKG 28337
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 28/204 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P+ + + S+++ W+ PLD GG +T G+ +++ E SP +
Sbjct: 15601 PPGKPKVLART--KGSMLVSWTPPLDNGG-SPIT--------GYWLEKREEGSPYWSRVS 15649
Query: 385 R----QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS-- 438
R + GL V LL Y F A+N PP + + + + P
Sbjct: 15650 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG--IGPPSEPSDPEVAGDPIFPPGP 15707
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT-- 495
P KD+T ++SISL W+ P G I Y V+ E E T + + +T
Sbjct: 15708 PSCPEVKDKT-KSSISLGWKPPAKDGGSPIKGYIVEMQE--EGTTDWKRVNEPDKLITTC 15764
Query: 496 ---ISSLKPDTIYVFQIRARTAAG 516
+ +LK Y F+++A AG
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAG 15788
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/197 (23%), Positives = 85/197 (43%), Gaps = 25/197 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP-RQFGLTN 391
++ +++ + + W+ P GG K +T G+ +++ E S R++P + +
Sbjct: 18404 VTKVSKEEMTVVWNPPEYDGG-KSIT--------GYFLEKKEKHS--TRWVPVNKSAIPE 18452
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
+ V +LL Y F + A N G+ E S P R A P P + T+
Sbjct: 18453 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE---PPGPPTNFRVVDTT 18509
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEK---QEQETSYTILRARGTNV----TISSLKP 501
++SI+L W +P + G I+ Y V+ K + + A V T++SL
Sbjct: 18510 KHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDE 18569
Query: 502 DTIYVFQIRARTAAGYG 518
+ Y F++ A+ G G
Sbjct: 18570 NQEYEFRVCAQNQVGIG 18586
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + ++ ++ L W+ PL GG K V ++I E N R++
Sbjct: 27857 PPGTPDYI--DVTRETITLKWNPPLRDGGSKIVGYSI------------EKRQGNERWVR 27902
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
F ++ TVT L Y F I A N V + SPP Q + + +T ++ P
Sbjct: 27903 CNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI-SPPSQSSGIIMTRDENVP 27955
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P V NI +V L W+ P TGG K +T I+ K+ PN R+L
Sbjct: 21359 PPGKP--VPLNITRHTVTLKWAKPEYTGGFK-ITSYIVEKRD----------LPNGRWLK 21405
Query: 385 RQFG-LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + TV+ L Y F + A N +S P A++ + AP + +
Sbjct: 21406 ANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDV 21465
Query: 444 K 444
K
Sbjct: 21466 K 21466
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 329 PRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
PRNV I++I++ SV L W P GG K +T I+ ++ P+ R+ F
Sbjct: 26771 PRNVRITDISKNSVSLSWQQPAFDGGSK-ITGYIVERRD----------LPDGRWTKASF 26819
Query: 388 -GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
+T T ++ L ++ Y F + A N V +S+P ++ + P
Sbjct: 26820 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP 26870
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 27/194 (13%)
Query: 332 VISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTN 391
VI + + S ++ W P D GG N + +KC + ++
Sbjct: 30731 VIEALLKNSAVISWKPPADDGG--SWITNYVVEKC--------EAKEGAEWQLVSSAISV 30780
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQ-----AAPSPVLTIK 444
TT + +L + Y F + A N G+S+ P + ++V I + A P +T
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISD----PLEVSSVVIIKSPFEKPGAPGKPTIT-- 30834
Query: 445 KDRTSRNSISLSWQEPEHPNGIILD--YEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W+ P G + Y K +KQ + S T R T ++ +L
Sbjct: 30835 --AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEG 30892
Query: 503 TIYVFQIRARTAAG 516
Y F+++ G
Sbjct: 30893 LEYEFRVKCENLGG 30906
Score = 38.1 bits (87), Expect = 0.021
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P +P ++ + + S+I+ W P GG + + + ++ K+ I+ R R
Sbjct: 22740 PKAPE--VTTVTKDSMIVVWERPASDGGSEILGY-VLEKRDKEGIRW-------TRCHKR 22789
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
G + VT L+ + +Y F + A N G+SE SPP + + P P
Sbjct: 22790 LIG--ELRLRVTGLIENHDYEFRVSAENAAGLSE-PSPPSAYQKACDPIYK--PGPPNNP 22844
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILR----ARGTNVTI 496
K +R+S+ LSW +P + G E++ Y ++ + S +T+ TN+ +
Sbjct: 22845 KVIDITRSSVFLSWSKPIYDGGC----EIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEV 22900
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNS 521
L Y F+I A AG G ++
Sbjct: 22901 EKLLEKHEYNFRICAINKAGVGEHA 22925
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++NI SV L WS P GG K G+ +++ E P+ R+L
Sbjct: 25687 PPGQPE--VTNITRKSVSLKWSKPHYDGGAKIT---------GYIVERRE--LPDGRWLK 25733
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + T VT+L Y F + A N +S P + + + P ++ +
Sbjct: 25734 CNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDV 25793
Query: 444 K 444
K
Sbjct: 25794 K 25794
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PPS P + V+++I E + + W+ P GG +T G+ +++ E VR
Sbjct: 17703 PPSPPGKPVVTDITENAATVSWTLPKSDGG-SPIT--------GYYMERREVTGKWVRV- 17752
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + VT L Y F + A N ++ LS P + P P +
Sbjct: 17753 -NKTPIADLKFRVTGLYEGNTYEFRVFAEN-LAGLSKPSPSSDPIKACRPIKPPGPPINP 17810
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVK 473
K SR + L W +P G IL Y V+
Sbjct: 17811 KLKDKSRETADLVWTKPLSDGGSPILGYVVE 17841
Score = 37.7 bits (86), Expect = 0.027
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T+T + + + + + + + A N V E+ ++I + P IK D S
Sbjct: 21119 TSTILNINECVRSDSGPYPLTARNIVGEVGD------VITIQVHDIPGPPTGPIKFDEVS 21172
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+ ++ SW PE+ G+ I +Y V+ +Q T++ L T + + T +Q
Sbjct: 21173 SDFVTFSWDPPENDGGVPISNYVVEM--RQTDSTTWVELATTVIRTTYKATRLTTGLEYQ 21230
Query: 509 IRARTAAGYG 518
R + YG
Sbjct: 21231 FRVKAQNRYG 21240
Score = 37.4 bits (85), Expect = 0.035
Identities = 40/200 (20%), Positives = 75/200 (37%), Gaps = 25/200 (12%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNV 380
RP ++N+ + + + W PLD GG + F + +K GW+I + +
Sbjct: 18001 RPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI 18060
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ +LLA+ Y F + A N GV A++ P
Sbjct: 18061 K---------------ANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPE 18105
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTI 496
+ K +T + L W+ P++ G L Y V+ K + + + T+ +
Sbjct: 18106 NLHIADKGKT---FVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMV 18162
Query: 497 SSLKPDTIYVFQIRARTAAG 516
+ IY F+++ + G
Sbjct: 18163 DRCVENQIYEFRVQTKNEGG 18182
Score = 37.4 bits (85), Expect = 0.035
Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 395 TVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T L+ Y F + AVN GV A + T A P + + NS
Sbjct: 28112 TAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP----EPSNITGNS 28167
Query: 453 ISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSLKPDTIYVFQI 509
I+L+W PE G I Y ++ EK+ I + T ++ L Y F +
Sbjct: 28168 ITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 28227
Query: 510 RARTAAGYGTNS 521
A AAG G S
Sbjct: 28228 MAENAAGVGPAS 28239
Score = 37.0 bits (84), Expect = 0.046
Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I +V L W P GG K +T I+ KK P+ R++
Sbjct: 24605 PPGRPEAIV--ITRNNVTLKWKKPAYDGGSK-ITGYIVEKKD----------LPDGRWMK 24651
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + T TV+ L+ Y F + A N S P A++ AP+ L
Sbjct: 24652 ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDP 24711
Query: 444 K 444
K
Sbjct: 24712 K 24712
Score = 37.0 bits (84), Expect = 0.046
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T T++++ + T+E+ N ++ P + + P P I+ D S
Sbjct: 25448 TVTSLSIKEASKEDVGTYELCVSNSAGSITVP----ITIIVLDRPGPPGP---IRIDEVS 25500
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+SI++SW PE+ G I +Y V+ +K+ T++ I+ +I ++ T +Q
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVE--KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQ 25558
Query: 509 IRARTAAGYGTNS 521
R YG +S
Sbjct: 25559 FRVCAENRYGKSS 25571
Score = 37.0 bits (84), Expect = 0.046
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 20/201 (9%)
Query: 324 RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRF 382
R P P + I +++ + L W P D GG + VT I+ +K ++ N
Sbjct: 29930 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ-VTGYIVERK---EVRADRWVRVN--- 29982
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAP-SP 439
+ +T T T L Y + A+N G + S P + A+ P +P
Sbjct: 29983 ---KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 30039
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE-TSYTILRARGTNVTIS 497
+T T+R S+SL+W PE G + Y ++ + + E T + T++
Sbjct: 30040 RVT----DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLT 30095
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y F++ A A G G
Sbjct: 30096 HLPQGAEYRFRVLACNAGGPG 30116
Score = 36.6 bits (83), Expect = 0.060
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + NI SV L W+ P GG K +T I+ K+ P+ ++
Sbjct: 20276 PPGKPE--VINITRNSVTLIWTEPKYDGGHK-LTGYIVEKRD----------LPSKSWMK 20322
Query: 385 -RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL-- 441
+ TVTDL+ Y F I A N +S+P + AP+ VL
Sbjct: 20323 ANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDP 20382
Query: 442 TIKKDRT 448
TIK T
Sbjct: 20383 TIKDGLT 20389
Score = 36.2 bits (82), Expect = 0.078
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PV +K ++ S +SW PE+ G + Y V+ E + S + T+
Sbjct: 18699 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 18758
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+++L P Y F++ A G G
Sbjct: 18759 VTNLVPGNEYYFRVTAVNEYGPG 18781
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/214 (21%), Positives = 78/214 (36%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P + + S+ L W P GG N I +K + + S V
Sbjct: 22243 PPTGPVKM-DEVTADSITLSWGPPKYDGGSS--INNYIVEKRDTSTTTWQIVSATV---- 22295
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT+ L Y F I A N G S + A +PV+T
Sbjct: 22296 -----ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 22350
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ +SR+S+ + W EP G + Y+ ++++ S ++ T + + K
Sbjct: 22351 L----SSRDSMEVQWNEPISDGG---SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTT 22403
Query: 503 TI-----YVFQIRARTAAGYGTNSRKFEFETSPD 531
+ Y F++ A G G S+ E + D
Sbjct: 22404 GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 22437
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/89 (26%), Positives = 37/89 (41%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTI 496
P P +K SR+S++L+W EP G + + E + +AR T T+
Sbjct: 31122 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTV 31181
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+L T Y F++ A G S E
Sbjct: 31182 INLFGKTSYQFRVIAENKFGLSKPSEPSE 31210
Score = 35.0 bits (79), Expect = 0.17
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ + T++ L+W P GG + V + + + G N + C+ +
Sbjct: 15002 PPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN--EWSRCTEKM-IKV 15058
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
RQ+ TV ++ +Y + AVN E PP + V++ Q P+ L +
Sbjct: 15059 RQY-------TVKEIREGADYKLRVSAVNAAGE--GPPGETQPVTVAEPQEPPAVELDV 15108
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 21/167 (12%)
Query: 305 RCENNYFRADK-DPPSMACTRP---PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
R EN + ++ P M P PS P+N ++ +N+ + + W P GG + +
Sbjct: 19067 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 19126
Query: 360 NIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGV-SEL 418
+I +K ++ + VR +T L+ Y+F I A+N S
Sbjct: 19127 -LIERKERNSLLWVKANDTLVR---------STEYPCAGLVEGLEYSFRIYALNKAGSSP 19176
Query: 419 SSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
S P ++ + + V+ + K +++SL W P+H G
Sbjct: 19177 PSKPTEYVTARMPVDPPGKPEVIDVTK-----STVSLIWARPKHDGG 19218
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 25/200 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +I + SV L W P GG K +T I+ KK P R++
Sbjct: 22441 PPGRPEAII--VTRNSVTLQWKKPTYDGGSK-ITGYIVEKKE----------LPEGRWMK 22487
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + +T VT L+ Y F + A N S P A++ P I
Sbjct: 22488 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPP----RI 22543
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYE--KQEQETSYTI-LRARGTNVTISSLK 500
D +++I + E + I + + K +QE S T L + T+ S
Sbjct: 22544 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 22603
Query: 501 PDTIYV----FQIRARTAAG 516
D + V + ++A+ AG
Sbjct: 22604 KDAVRVDSGNYILKAKNVAG 22623
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ V + ++++++ W P++ GG + + +++ K+ S +
Sbjct: 25589 PPGTPKVV--HATKSTMLVTWQVPVNDGGSRVIGYHLEYKER----------SSILWSKA 25636
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T + V+ L Y + + A N G+ + S A P
Sbjct: 25637 NKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVT-- 25694
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R S+SL W +P + G I Y V+ E + + +YT ++ T ++
Sbjct: 25695 ----NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE--TYFEVTE 25748
Query: 499 LKPDTIYVFQIRARTAA 515
L D Y F++ AR AA
Sbjct: 25749 LTEDQRYEFRVFARNAA 25765
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 14/127 (11%)
Query: 317 PPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
P + T P+ PR + + + +++S +L W P GG + + + ++ G +
Sbjct: 28537 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSD------ 28590
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
F T TV L+ T Y F + A N S P F++V I Q
Sbjct: 28591 ------FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAG-YSEPREAFSSVIIKEPQI 28643
Query: 436 APSPVLT 442
P+ LT
Sbjct: 28644 EPTADLT 28650
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P IK +++S L+W+ PE G IL Y ++ E + + + T
Sbjct: 14480 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 14539
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+ L P+ Y F+++A G G
Sbjct: 14540 VKDLIPNGEYFFRVKAVNKVGGG 14562
Score = 34.3 bits (77), Expect = 0.30
Identities = 39/183 (21%), Positives = 70/183 (38%), Gaps = 18/183 (9%)
Query: 337 NETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTV 396
N +L+WS P D GG ++T II +K +P + +
Sbjct: 15209 NRKMCLLNWSDPEDDGG-SEITGFIIERKDAKMHTWRQPIETE-----------RSKCDI 15256
Query: 397 TDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLS 456
T LL Y F + A N PP + + P+ + ++++I+L
Sbjct: 15257 TGLLEGQEYKFRVIAKNKFG--CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 15314
Query: 457 WQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRART 513
W+EP G + E + ++K + E L T+ + +L +Y F+++A
Sbjct: 15315 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYEFRVKAVN 15373
Query: 514 AAG 516
G
Sbjct: 15374 EIG 15376
Score = 34.3 bits (77), Expect = 0.30
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P ++K SR+S++++W+ P G + +Y V+ E + + T
Sbjct: 29538 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 29597
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
IS L T+Y F++ G G
Sbjct: 29598 ISGLVEGTMYYFRVLPENIYGIG 29620
Score = 33.9 bits (76), Expect = 0.39
Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T + + + D L + + I A N +FAA + P PVL +K T+
Sbjct: 15157 TKSELIIKDALRKDHGRYVITATNSCGS------KFAAARVEVFDV-PGPVLDLKPVVTN 15209
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
R L+W +PE G + + + + T + + I+ L Y F++
Sbjct: 15210 RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRV 15269
Query: 510 RARTAAGYG 518
A+ G G
Sbjct: 15270 IAKNKFGCG 15278
Score = 33.9 bits (76), Expect = 0.39
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
++N R R K +M PP P+N +++ TSV L WS P D GG K +
Sbjct: 30008 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 30067
Query: 360 NIICKK 365
I +K
Sbjct: 30068 LIEMQK 30073
Score = 33.5 bits (75), Expect = 0.51
Identities = 39/194 (20%), Positives = 79/194 (40%), Gaps = 17/194 (8%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P + ++ SV + W P GG N I +K ++ + +
Sbjct: 29538 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAP--VNNYIVEKREAAMRAFKTVTTKC---- 29591
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T ++ L+ T Y F + N + + P AV ++ P+ + +
Sbjct: 29592 -----SKTLYRISGLVEGTMYYFRVLPEN-IYGIGEPCETSDAVLVSEVPLVPAKLEVVD 29645
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV--TISSLKPD 502
++++++L+W++P + G L V K E ++ + T + T++SL
Sbjct: 29646 ---VTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEG 29702
Query: 503 TIYVFQIRARTAAG 516
Y+F+IRA+ G
Sbjct: 29703 EQYLFRIRAQNEKG 29716
Score = 33.1 bits (74), Expect = 0.66
Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PP+SP R + ++++ LDW P GG G+ I++ P+ +
Sbjct: 15294 PPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQ---------GYIIEKRRHDKPDFERV 15344
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
++ T T+ V +L H Y F + AVN + E S P V I ++ P TI
Sbjct: 15345 NKRLCPT-TSFLVENLDEHQMYEFRVKAVNEIGE--SEPSLPLNVVIQDDEVPP----TI 15397
Query: 444 KKDRTSR-NSISLSWQEPEHPNGIILDYEVKYYEKQEQET 482
K + R ++I + EP H + + E + ET
Sbjct: 15398 KLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNET 15437
Score = 32.7 bits (73), Expect = 0.86
Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 7/129 (5%)
Query: 391 NTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
++ +T+ + L ++I N + AV +T P I +
Sbjct: 17565 SSVLTIKNCLRRDTGEYQITVSNAAGSKT------VAVHLTVLDVPGPPTGPINILDVTP 17618
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+++SWQ P+ G +++Y V+ + ++ + T + I L+ YVF++
Sbjct: 17619 EHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 17678
Query: 510 RARTAAGYG 518
RA G G
Sbjct: 17679 RAENKIGVG 17687
Score = 32.7 bits (73), Expect = 0.86
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PVL ++ +++S++L W P G I +Y V+ E + S +
Sbjct: 20868 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 20927
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L Y F++ A G G
Sbjct: 20928 VTGLSEGCEYFFRVMAENEYGIG 20950
Score = 32.7 bits (73), Expect = 0.86
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 8/138 (5%)
Query: 392 TTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
TT T L Y F + A N P A + P P T + +++
Sbjct: 21216 TTYKATRLTTGLEYQFRVKAQNRYGV--GPGITSACIVANYPFKVPGPPGTPQVTAVTKD 21273
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISSLKPDTIYVF 507
S+++SW EP G IL Y V+ E+ Q S ++ G S L Y F
Sbjct: 21274 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV--PGNIFKSSGLTDGIAYEF 21331
Query: 508 QIRARTAAGYGTNSRKFE 525
++ A AG S+ E
Sbjct: 21332 RVIAENMAGKSKPSKPSE 21349
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 37/151 (24%)
Query: 318 PSMACT--RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WN-- 369
P AC +PP P N + + + + L W+ PL GG + + + C+K G WN
Sbjct: 17794 PIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRI 17853
Query: 370 -----IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ 424
I+QC V L+ Y F I A N V E PR+
Sbjct: 17854 NKDELIRQC-------------------AFRVPGLIEGNEYRFRIKAANIVGE--GEPRE 17892
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
A I + P V + D T R+ I++
Sbjct: 17893 LAESVIAKDILHPPEV---ELDVTCRDVITV 17920
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 9/99 (9%)
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSY 484
F A + P PV +K S + ++ W PE G E++ Y ++ ET
Sbjct: 18285 FVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGC----EIQNYILEKCETKR 18340
Query: 485 TILRARGTNV-----TISSLKPDTIYVFQIRARTAAGYG 518
+ V T++ L Y+F++RA G G
Sbjct: 18341 MVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 18379
Score = 31.6 bits (70), Expect = 1.9
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P ++ NE + L W+ P+ GG +T I+ K+ P+ R++
Sbjct: 23523 PPGTPEPIMVKRNE--ITLQWTKPVYDGGSM-ITGYIVEKRD----------LPDGRWMK 23569
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
F + T TV+ L Y F + A N +S P
Sbjct: 23570 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKP 23607
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 437 PSPVLT-IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
P PV T + S L+W PE G I +Y ++ E + +YT+ R
Sbjct: 16616 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ-- 16673
Query: 492 TNVTISSLKPDTIYVFQIRARTAAGYG 518
N T+ L Y F+I A + G G
Sbjct: 16674 -NATVQGLIQGKAYFFRIAAENSIGMG 16699
Score = 30.4 bits (67), Expect = 4.3
Identities = 23/99 (23%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P +K +R S LSW+ P+ G I Y ++ + + T
Sbjct: 15912 PGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFV 15971
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++RA G G + T+ D +Y
Sbjct: 15972 VPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIY 16010
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 426 AAVSITTNQAAPSPV-LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETS 483
A V++ + +PV LTI++ ++S++LSW+ P G I +Y V+ E + +
Sbjct: 25189 AFVNVRVLDSPSAPVNLTIRE--VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 25246
Query: 484 YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
T I +L+ Y F++ A G G
Sbjct: 25247 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 25281
Score = 29.6 bits (65), Expect = 7.3
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILRARGT 492
+P P + R ++ +L+W P+ G E+ +Y + +ETS + I+
Sbjct: 29140 SPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA----EITHYIVERRETSRLNWVIVEGECP 29195
Query: 493 NVT--ISSLKPDTIYVFQIRARTAAGYG 518
++ ++ L + Y+F++RA G G
Sbjct: 29196 TLSYVVTRLIKNNEYIFRVRAVNKYGPG 29223
Score = 29.6 bits (65), Expect = 7.3
Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 9/128 (7%)
Query: 393 TVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T+ T + YT E+ V G + + + P IK D S
Sbjct: 29797 TIRETTIRDTGEYTLELKNVTGTTS--------ETIKVIILDKPGPPTGPIKIDEIDATS 29848
Query: 453 ISLSWQEPEHPNGIILD-YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
I++SW+ PE G L Y V+ + + + L YVF++ A
Sbjct: 29849 ITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAA 29908
Query: 512 RTAAGYGT 519
G G+
Sbjct: 29909 TNRFGIGS 29916
Score = 29.6 bits (65), Expect = 7.3
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
+P + + I+ + + S ++ W P GG K + + ++ N K + +R
Sbjct: 30824 KPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQN-KWISVTTEEIR-- 30880
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVL 441
T +V +L+ Y F + N G SE S + IT P
Sbjct: 30881 -------ETVFSVKNLIEGLEYEFRVKCENLGGESEWSE-----ISEPITPKSDVPIQAP 30928
Query: 442 TIKKDRTSRN-----SISLSWQEPEHPNGIILDYEVKYYEKQEQETS----YTILRARGT 492
K++ + N + +L + HP I VK+Y + ++ + Y I +G
Sbjct: 30929 HFKEELRNLNVRYQSNATLVCKVTGHPKPI-----VKWYRQGKEIIADGLKYRIQEFKGG 30983
Query: 493 --NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFE 527
+ I+S+ D V+Q+RA G + + E E
Sbjct: 30984 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 31020
Score = 29.3 bits (64), Expect = 9.5
Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 20/158 (12%)
Query: 286 KCAKCPPHSSTQEDGS---MNCRCENNYFRADKDPPS--MACTRPPSSPRNV-ISNINET 339
KC KC + +G EN Y + + + + PS P ++ I +I ++
Sbjct: 20920 KCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKS 20979
Query: 340 SVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDL 399
+V L W P GG K + I ++ G S + GL V +L
Sbjct: 20980 TVSLAWPKPKHDGGSKITGYVIEAQRKG---------SDQWTHITTVKGL---ECVVRNL 21027
Query: 400 LAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
YTF++ AVN S PR+ V + P
Sbjct: 21028 TEGEEYTFQVMAVNSAGR--SAPRESRPVIVKEQTMLP 21063
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 63.2 bits (152), Expect = 6e-10
Identities = 58/199 (29%), Positives = 91/199 (45%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PPS+P +S I + S+++ W+ P+D GG ++ I+ K+ ++ + C+
Sbjct: 18599 PPSTPE--VSAITKDSMVVTWARPVDDGGT-EIEGYILEKRDKEGVRWTK-CNKKT---- 18650
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ + VT L +Y F + A N GV E S P + A P P
Sbjct: 18651 ----LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY---PPGPPSN 18703
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
K TSR+S+SL+W +P + G + EVK E T +G T++ L
Sbjct: 18704 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKL 18763
Query: 500 KPDTIYVFQIRARTAAGYG 518
K +T Y F+I A + G G
Sbjct: 18764 KENTEYNFRICAINSEGVG 18782
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 30/205 (14%)
Query: 324 RPPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSP 378
R P +P + +++ + + S ++ W+ P D G K +T I+ K+ W +P P
Sbjct: 10705 RVPDAPDQPIVTEVTKDSALVTWNKPHDGG--KPITNYILEKRETMSKRWARVTKDPIHP 10762
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQ-FAAVSITTNQA 435
+F V DLL Y F + A N G+ + S P + FA I A
Sbjct: 10763 YTKF------------RVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI----A 10806
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
PSP + + T+ NS+ L+WQ P H G IL Y V+Y + ++E ++T
Sbjct: 10807 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 10866
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T ++ L+ Y F++ A AAG
Sbjct: 10867 TKYKVTGLRDGQTYKFRVLAVNAAG 10891
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I + S+ + WS P+ GG D++ + K+ ++ + +R
Sbjct: 20763 PPGIPE--VTKITKNSMTVVWSRPIADGG-SDISGYFLEKRDKKSLGWFKVLKETIR--- 20816
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T VT L +++Y + + AVN G S P + A P P
Sbjct: 20817 ------DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID---PPGPPAK 20867
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
I+ ++++SI+L W +P + G + E++ E++E T T R T +S+L
Sbjct: 20868 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20927
Query: 500 KPDTIYVFQIRARTAAGYG 518
KP Y F++ A AG G
Sbjct: 20928 KPGVNYYFRVSAVNCAGQG 20946
Score = 59.3 bits (142), Expect = 9e-09
Identities = 66/205 (32%), Positives = 94/205 (45%), Gaps = 36/205 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PPS+P V+ ++ ++SV L WS P D GG + VT G+ I++ E + VR
Sbjct: 24026 PPSNPPEVL-DVTKSSVSLSWSRPKDDGGSR-VT--------GYYIERKETSTDKWVRHN 24075
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELS--SPPRQFAAVSITTNQAAPSP 439
Q +T T TVT L+ Y F I A N G+SE S S P +Q
Sbjct: 24076 KTQ--ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKY-------YEKQEQETSYTILRARG 491
+L+I KD S++L W++PE G IL Y V+Y ++K +E R +
Sbjct: 24134 ILSISKD-----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE------RIKD 24182
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
TI L T Y F++ A G
Sbjct: 24183 KQFTIGGLLEATEYEFRVFAENETG 24207
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 316 DPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
DPP PP P + ++ +TSV L+W+ P GG K ++ I K G +
Sbjct: 7677 DPPW-----PPGKP--TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTD------ 7723
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
++ G+ T + L+ Y+F + AVN E S P V
Sbjct: 7724 -----EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGE-SEPSEPSDPVLCREKLY 7777
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV 494
PSP ++ ++N+ L W PE G I +Y V+ + + + + T
Sbjct: 7778 PPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7837
Query: 495 TISSLKPDTIYVFQIRARTAAG 516
T++ L ++YVF++ A A G
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIG 7859
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 28/243 (11%)
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRN-VISNINETSVILDWSWPLDTGGRKD 356
+ G + EN++ A K P +++ P P N V +I +TSV+ W PLD GG +
Sbjct: 8470 DHGLYMIKVENDHGIA-KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8528
Query: 357 VTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVS 416
+ + +++ + P+ ++ L + +VT L+ Y F + A N
Sbjct: 8529 INY---------TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN--- 8576
Query: 417 ELSSPPRQFAAVSITTNQAAP--SPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY 474
P + + + P +P I +D TS NS+ + W EP+ IL Y +
Sbjct: 8577 RFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS-NSMLVKWNEPKDNGSPILGY---W 8632
Query: 475 YEKQEQETSY------TILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
EK+E +++ ++L A NV L YVF++ A AAG G S + +T
Sbjct: 8633 LEKREVNSTHWSRVNKSLLNALKANV--DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKT 8690
Query: 529 SPD 531
+ D
Sbjct: 8691 AHD 8693
Score = 56.2 bits (134), Expect = 7e-08
Identities = 60/223 (26%), Positives = 88/223 (39%), Gaps = 19/223 (8%)
Query: 307 ENNYFRADKDPPSMACTRPPSSPRN-----VISNINETSVILDWSWPLDTGGRKDVTFNI 361
EN Y D A + P P VISNI + + + W P D GG +T
Sbjct: 13160 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGG-SPIT--- 13215
Query: 362 ICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
G+ +++ E + N + R+ + T+ T L T Y F + A+N P
Sbjct: 13216 -----GYLLEKRETQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGP-GKP 13268
Query: 422 PRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDY--EVKYYEKQ 478
A Q P P K T+R+S+SLSW +P + G I+ Y EVK +
Sbjct: 13269 SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSD 13328
Query: 479 EQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS 521
+ T ++ L DT Y F++ A GY S
Sbjct: 13329 NWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13371
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/190 (25%), Positives = 89/190 (46%), Gaps = 22/190 (11%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S++ +TS + W+ P + GG + VT I+ K+ + K +P V+ T
Sbjct: 12402 VSDVTKTSCHVSWAPPENDGGSQ-VTHYIVEKREA-DRKTWSTVTPEVK---------KT 12450
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT+L+ Y F + AVN G + P+ A + + P P ++ ++
Sbjct: 12451 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA---SDPLSEPDPPRKLEVTEMTK 12507
Query: 451 NSISLSWQEPEHPNGIILDYEVKYYEKQEQE----TSYTILRARGTNVTISSLKPDTIYV 506
NS +L+W P G +D + Y ++EQ T Y+++ + ++ ++ LK Y
Sbjct: 12508 NSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV--KDLSLVVTGLKEGKKYK 12565
Query: 507 FQIRARTAAG 516
F++ AR A G
Sbjct: 12566 FRVAARNAVG 12575
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/222 (26%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L WS PL GG D++ ++ K+ W + E
Sbjct: 17416 PPEGPVQV-TGVTSEKCSLTWSPPLQDGG-SDISHYVVEKRETSRLAWTVVASE------ 17467
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ ++ VT LL Y F I AVN GV E P + A V + P
Sbjct: 17468 --------VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE----PLESAPVLMKNPFVLPG 17515
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTN 493
P +++ +++S+++ W P+ G I+ Y V EK+++ I R
Sbjct: 17516 PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV---EKRDRSGIRWIKCNKRRITDLR 17572
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYY 535
+ ++ L D Y F++ A AAG G E SP +YY
Sbjct: 17573 LRVTGLTEDHEYEFRVSAENAAGVG--------EPSPATVYY 17606
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 319 SMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSP 378
S PP P V + +I+ W+ P GG +++ ++ K+ E S
Sbjct: 22931 SFTIPSPPGIPEEV--GTGKEHIIIQWTKPESDGGN-EISNYLVDKR--------EKKSL 22979
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
+ + + + +T + VT L+ +Y F + AVN S P +S P
Sbjct: 22980 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN-SEPSEASNFISCREPSYTPG 23038
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE--TSYTILRARGTNVT 495
P + T+++SISL+W +P + G I+ Y ++ EK + +T R T T
Sbjct: 23039 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 23098
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
+ LK Y F++ A G
Sbjct: 23099 VPDLKMGQKYSFRVAAVNVKG 23119
Score = 55.5 bits (132), Expect = 1e-07
Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 29/237 (12%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTR-------PPSSPRNVISNINETSVILDWSW 347
+T E+ + EN + +D + + PPS+P ++N+ S+ + W
Sbjct: 20330 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPW--VTNVTRESITVGWHE 20387
Query: 348 PLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTF 407
P+ GG V +++ K + Q + + T VT + A Y F
Sbjct: 20388 PVSNGGSAVVGYHLEMKDRNSILWQ----------KANKLVIRTTHFKVTTISAGLIYEF 20437
Query: 408 EIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
+ A N GV + S P A+ A P ++ S+NS+SLSWQ+P G
Sbjct: 20438 RVYAENAAGVGKPSHPSEPVLAID------ACEPPRNVRITDISKNSVSLSWQQPAFDGG 20491
Query: 466 I-ILDYEVKYYEKQE-QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTN 520
I Y V+ + + + T + T IS L ++ Y F++ AR A G +N
Sbjct: 20492 SKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISN 20548
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 24/207 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P VIS+I E SV L W P GG + VT I+ K+ E + R
Sbjct: 20267 PPTGPV-VISDITEESVTLKWEPPKYDGGSQ-VTNYILLKRETSTAVWTEVSATVAR--- 20321
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
T + V L Y F I A N G+S+ A V++ P P T
Sbjct: 20322 -------TMMKVMKLTTGEEYQFRIKAENRFGISDHIDS----ACVTVKLPYTTPGPPST 20370
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R SI++ W EP G ++ Y ++ ++ Q+ + ++R T+ +++
Sbjct: 20371 PWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT--THFKVTT 20428
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFE 525
+ IY F++ A AAG G S E
Sbjct: 20429 ISAGLIYEFRVYAENAAGVGKPSHPSE 20455
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 24/196 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P N+ + ++ + S +L W P + GG ++I K W + C+
Sbjct: 19973 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW-VSVTNNCN---- 20027
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
+ VT+L Y F + N + P V IT PSP
Sbjct: 20028 ---------RLSYKVTNLQEGAIYYFRVSGENEFG-VGIPAETKEGVKITEK---PSPPE 20074
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ S++S+SL+W +PEH G I+ Y V+ EK Q+ A+ T+ +S L+
Sbjct: 20075 KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEK-GQKNWVKCAVAKSTHHVVSGLR 20133
Query: 501 PDTIYVFQIRARTAAG 516
++ Y F++ A AG
Sbjct: 20134 ENSEYFFRVFAENQAG 20149
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/193 (26%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ + + +TSV L W PL GG K N I +K K + N
Sbjct: 15647 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSK--IKNYIVEKRESTRKAYSTVATNCH--- 15701
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T+ V L +Y F + A N + P +V + P + +
Sbjct: 15702 ------KTSWKVDQLQEGCSYYFRVLAENEYG-IGLPAETAESVKASERPLPPGKITLMD 15754
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RNS+SLSW++PEH G IL Y V+ K + + T + T TI+ L
Sbjct: 15755 ---VTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA-TCATVKVTEATITGLIQGE 15810
Query: 504 IYVFQIRARTAAG 516
Y F++ A+ G
Sbjct: 15811 EYSFRVSAQNEKG 15823
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 26/197 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS P N+ ++ I + SV + W PL GG K N I +K K N
Sbjct: 16729 PSPPVNLKVTEITKDSVSITWEPPLLDGGSK--IKNYIVEKREATRKSYAAVVTNCH--- 16783
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN----GVSELSSPPRQFAAVSITTNQAAPSPV 440
+ + L +Y F + A N G+ ++ P + A V P P
Sbjct: 16784 ------KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV--------PQPP 16829
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSL 499
I D +RNS+SLSW +PEH G I+ Y V+ K ++ S R + I++L
Sbjct: 16830 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWS-ECARVKSLQAVITNL 16888
Query: 500 KPDTIYVFQIRARTAAG 516
Y+F++ A G
Sbjct: 16889 TQGEEYLFRVVAVNEKG 16905
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/202 (26%), Positives = 93/202 (46%), Gaps = 26/202 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PP P +SN+ + + + W P+D GG ++T G+++++ E S VR +
Sbjct: 14269 PPEKPE--VSNVTKNTATVSWKRPVDDGG-SEIT--------GYHVERREKKSLRWVRAI 14317
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA--PSPVL 441
+ +++ VT L + Y F + A N PP + A+ S+ AA P P
Sbjct: 14318 --KTPVSDLRCKVTGLQEGSTYEFRVSAENRAG--IGPPSE-ASDSVLMKDAAYPPGPPS 14372
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ----ETSYTILRARGTNVTI 496
T++ S SL+W +P + G+ I Y V++ + ++ +T+ T LR T +
Sbjct: 14373 NPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI--TQFVV 14430
Query: 497 SSLKPDTIYVFQIRARTAAGYG 518
L+ Y F+I A AG G
Sbjct: 14431 PDLQTKEKYNFRISAINDAGVG 14452
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P VI N+ + L W P+ GG + F++ K+ + Q SP
Sbjct: 21454 PPGKP--VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSP------ 21505
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
++ T L+ +Y F + A N G+S S P + AVS P +
Sbjct: 21506 ----ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI-- 21559
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+R +I+L W P G I+ Y ++ + E+ T++ L P
Sbjct: 21560 ----DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSP 21615
Query: 502 DTIYVFQIRARTAAG 516
Y F+I AR A G
Sbjct: 21616 GDRYEFRIIARNAVG 21630
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P N+ I + + SV L W PL GG K N I +K K + N
Sbjct: 18894 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKIT--NYIVEKRETTRKAYATITNNC---- 18947
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T TT + +L +Y F + A N + P V ++ P V +
Sbjct: 18948 -----TKTTFRIENLQEGCSYYFRVLASNEYG-IGLPAETTEPVKVSEPPLPPGRVTLVD 19001
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RN+ ++ W++PE G I Y V+ K ++ S T + + TIS L
Sbjct: 19002 ---VTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-TCTQVKTLEATISGLTAGE 19057
Query: 504 IYVFQIRARTAAG 516
YVF++ A G
Sbjct: 19058 EYVFRVAAVNEKG 19070
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/217 (24%), Positives = 85/217 (39%), Gaps = 39/217 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP+ P I+ + L W P + GG D+ + I+ K+ W I + E
Sbjct: 19580 PPAGPLE-INGLTAEKCSLSWGRPQEDGGA-DIDYYIVEKRETSHLAWTICEGE------ 19631
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L T+ VT LL Y F + VN GV E P + A+ PS
Sbjct: 19632 --------LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE----PLESVAIKALDPFTVPS 19679
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRAR-----GTN 493
P +++ ++ S++L W PE G + Y ++ ++ S +R
Sbjct: 19680 PPTSLEITSVTKESMTLCWSRPESDGGSEIS---GYIIERREKNSLRWVRVNKKPVYDLR 19736
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
V + L+ Y +++ A AAG S ETSP
Sbjct: 19737 VKSTGLREGCEYEYRVYAENAAGLSLPS-----ETSP 19768
Score = 49.3 bits (116), Expect = 9e-06
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S+++ S +L W P D GG + + + ++ G Q S + T
Sbjct: 22445 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-----------VKRT 22493
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT L + Y+F + + N GVS+ P + A + PS + S
Sbjct: 22494 QIKVTHLTKYMEYSFRVSSENRFGVSK----PLESAPIIAEHPFVPPSAPTRPEVYHVSA 22549
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRAR----GTNVTISSLKPDTIY 505
N++S+ W+EP H G I+ Y + EK+E+ T + + N ++ L Y
Sbjct: 22550 NAMSIRWEEPYHDGGSKIIGY---WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEY 22606
Query: 506 VFQIRARTAAG 516
F+ A AAG
Sbjct: 22607 QFRTYALNAAG 22617
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 20/201 (9%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL- 383
P + + +S++ S+ ++W P GG VT G+ ++ + S + +
Sbjct: 10012 PGAPDKPTVSSVTRNSMTVNWEEPEYDGG-SPVT--------GYWLEMKDTTSKRWKRVN 10062
Query: 384 --PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
P + + VT L+ ++Y F + A+N GV S P A P P
Sbjct: 10063 RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP 10122
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSY-TILRARGTNVTIS 497
+T +++S L W P G + Y V+Y E+ ++E RGT + ++
Sbjct: 10123 KVT----DWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 10178
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
LK Y F++RA AG G
Sbjct: 10179 GLKEGAFYKFRVRAVNIAGIG 10199
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + IS+I+ + L W PL+ GG ++T N I +KC ++ + + ++
Sbjct: 12689 PPQPPFD-ISDIDADACSLSWHIPLEDGG-SNIT-NYIVEKC--DVSRGD-------WVT 12736
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T T+ V L+ Y F + A N G+SE + P+ A PS
Sbjct: 12737 ALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF----GVPSEPKN 12792
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRA-----RGTNVTIS 497
+ + +++ I ++W P+ G + + Y ++++ S ++A R T +
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPI---IGYLIERKERNSLLWVKANDTLVRSTEYPCA 12849
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETS 529
L Y F+I A AG S+ E+ T+
Sbjct: 12850 GLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA 12881
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICK-KCGWNIKQCEPCSPNVRF 382
PP P+N ++ I + S+++ W P GG + + + + + K G +C +
Sbjct: 15349 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT----- 15403
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ V+ L Y F I A N +S+P P P
Sbjct: 15404 ------LTDLRYKVSGLTEGHEYEFRIMAENAAG-ISAPSPTSPFYKACDTVFKPGPPGN 15456
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSL 499
+ TSR+SIS++W +P + G I Y V+ +E E A + T+ TI+ L
Sbjct: 15457 PRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGL 15516
Query: 500 KPDTIYVFQIRARTAAGYG 518
+ Y +I A + G G
Sbjct: 15517 TENQEYKIRIYAMNSEGLG 15535
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 26/210 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIK--QCEPCSPN 379
P RN+ ++ + V L W PL GG K + + + K+ W + + E C
Sbjct: 6785 PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6844
Query: 380 VRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP 439
V L + Y F + A N V P V + P P
Sbjct: 6845 VTGLQK---------------GGVEYLFRVSARNRVGT-GEPVETDNPVEARSKYDVPGP 6888
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQ--EQETSYTILRARGTNVTI 496
L + +R +SL+W+ PE+ G I +Y ++ +K +T+ T+ RA + T+
Sbjct: 6889 PLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTV-RAEDLSATV 6947
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+ + Y F++RA+ G G S F
Sbjct: 6948 TDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6977
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/261 (23%), Positives = 95/261 (36%), Gaps = 38/261 (14%)
Query: 287 CAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP--PSSPRNVISNINETSVILD 344
C P S + G NN A K+ RP P P +++ + L
Sbjct: 9874 CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIK-FESVSADQMTLS 9932
Query: 345 WSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLA 401
W P D GG K + I ++ W EP T T+ LL
Sbjct: 9933 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP--------------KECTYTIPKLLE 9978
Query: 402 HTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQE 459
Y F I A N G+ E + A + A P ++ +RNS++++W+E
Sbjct: 9979 GHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVS----SVTRNSMTVNWEE 10034
Query: 460 PEHPNGIILDYEVKYYEKQEQETSYTILRAR---------GTNVTISSLKPDTIYVFQIR 510
PE+ G + Y+ + + TS R G + ++ L + Y F++
Sbjct: 10035 PEYDGGSPV---TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVY 10091
Query: 511 ARTAAGYGTNSRKFEFETSPD 531
A AAG G S + T+ D
Sbjct: 10092 AINAAGVGPASLPSDPATARD 10112
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/199 (24%), Positives = 89/199 (44%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P +++I++ +++ W P++ GG K + G++++Q E S L
Sbjct: 18202 PPGTP--FVTSISKDQMLVQWHEPVNDGGTKII---------GYHLEQKEKNSILWVKLN 18250
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T T L Y F++ A N G+ + S F A P ++
Sbjct: 18251 KT-PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18309
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RN+++L W++P + G + Y +++ ++A TNV T+S
Sbjct: 18310 ------TRNNVTLKWKKPAYDGGSKI---TGYIVEKKDLPDGRWMKASFTNVLETEFTVS 18360
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ AR AAG
Sbjct: 18361 GLVEDQRYEFRVIARNAAG 18379
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 15/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PS P ++ I+++ + S+ L WS P GG + G+ I++ E S VR
Sbjct: 19678 PSPPTSLEITSVTKESMTLCWSRPESDGGSEI---------SGYIIERREKNSLRWVRVN 19728
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + V T L Y + + A N LS P + PSP
Sbjct: 19729 KKP--VYDLRVKSTGLREGCEYEYRVYAENAAG-LSLPSETSPLIRAEDPVFLPSPPSKP 19785
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
K + + +I+++W +P G I Y V+Y + + + +I RGT TIS L
Sbjct: 19786 KIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTG 19845
Query: 503 TIYVFQIRARTAAG 516
YVF++++ G
Sbjct: 19846 AEYVFRVKSVNKVG 19859
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 29/222 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS PRN+ +++I S L W PLD GG ++T +I K+ + K+ E +
Sbjct: 9193 PSPPRNLAVTDIKAESCYLTWDAPLDNGG-SEITHYVIDKRDA-SRKKAEWEEVTNTAVE 9250
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+++G + L+ + Y F + AVN G+S+ + V I P P
Sbjct: 9251 KRYG-------IWKLIPNGQYEFRVRAVNKYGISDECKSDK----VVIQDPYRLPGPPGK 9299
Query: 443 IKKDRTSRNSISLSWQEP-EHPNGIILDYEVKYYEKQEQETSY---------TILRARGT 492
K ++ S+ +SW P ++ I Y + EK+E+ + Y T + +G
Sbjct: 9300 PKVLARTKGSMLVSWTPPLDNGGSPITGY---WLEKREEGSPYWSRVSRAPITKVGLKGV 9356
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L Y F+ A AAG G S + E + D ++
Sbjct: 9357 EFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIF 9398
Score = 47.8 bits (112), Expect = 3e-05
Identities = 53/254 (20%), Positives = 92/254 (36%), Gaps = 38/254 (14%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+T++D N F + + P P V ISN++ L W+ PL+ GG
Sbjct: 14137 ATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGG 14196
Query: 354 --------RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNY 405
K T ++ +I+ C T L+ Y
Sbjct: 14197 SPIKSYILEKRETSRLLWTVVSEDIQSCRH-------------------VATKLIQGNEY 14237
Query: 406 TFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
F + AVN + P Q V + P P + ++N+ ++SW+ P G
Sbjct: 14238 IFRVSAVNHYGK--GEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGG 14295
Query: 466 IILDYEVKYYEKQEQETSYTILRARGTNVT-----ISSLKPDTIYVFQIRARTAAGYGTN 520
+ Y+ ++ ++ S +RA T V+ ++ L+ + Y F++ A AG G
Sbjct: 14296 SEI---TGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPP 14352
Query: 521 SRKFEFETSPDCMY 534
S + D Y
Sbjct: 14353 SEASDSVLMKDAAY 14366
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/198 (22%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICK---KCGWNIKQCEPCSPNVR 381
P + + + +++ +V L W PL GG + + I + K W++ CS
Sbjct: 21061 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVS-HKCS---- 21115
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
+T+ + DL T + F + A N G+ E A + P+P
Sbjct: 21116 ---------STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV------PAP 21160
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
+ + +++ S+ LSW +P+ G +I +Y V+ K EQ S+ + ++ + +S
Sbjct: 21161 IRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI-SKTCEIEVSQ 21219
Query: 499 LKPDTIYVFQIRARTAAG 516
LK ++ F++ A+ G
Sbjct: 21220 LKEQSVLEFRVFAKNEKG 21237
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P + P I ++ SV L W+ P TGG +++ K+ + + +P +R
Sbjct: 13871 PDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTP-IRM-- 13927
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
R F VT L Y F + A+N GV + S P A+ P +
Sbjct: 13928 RDF-------KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVI-- 13978
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RNS++L W EP++ G L Y ++ S + ++A NV T++
Sbjct: 13979 ----NITRNSVTLIWTEPKYDGGHKL---TGYIVEKRDLPSKSWMKANHVNVPECAFTVT 14031
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+IRA+ AG
Sbjct: 14032 DLVEGGKYEFRIRAKNTAG 14050
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 25/200 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
I+++ S +L W+ P D GG K N + ++ + + S V+ +T
Sbjct: 7487 ITDVTNESCLLTWNPPRDDGGSK--ITNYVVERRATDSEVWHKLSSTVK---------DT 7535
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
T L+ + Y F + A N GV E P Q + ++ P P ++ ++
Sbjct: 7536 NFKATKLIPNKEYIFRVAAENMYGVGE----PVQASPITAKYQFDPPGPPTRLEPSDITK 7591
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTNVTISSLKPDTIY 505
++++L+W EP+ G I Y + E+ + +T + + + T + L Y
Sbjct: 7592 DAVTLTWCEPDDDGGSPITGY---WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKY 7648
Query: 506 VFQIRARTAAGYGTNSRKFE 525
F++ A AG G S+ E
Sbjct: 7649 RFRVLAENLAGPGKPSKSTE 7668
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ ++ + + S+ + W PL GG + +++ K+ + Q + +
Sbjct: 14956 PPGTPQ--VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 15013
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ GLT+ Y F + A N G S+ S P A+ P P+
Sbjct: 15014 KSSGLTDGIA----------YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL-- 15061
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+R++++L W +PE+ G + Y ++ + L+A +N+ T+S
Sbjct: 15062 ----NITRHTVTLKWAKPEYTGGFKI---TSYIVEKRDLPNGRWLKANFSNILENEFTVS 15114
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 15115 GLTEDAAYEFRVIAKNAAG 15133
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 42/225 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L W+ PL GG +++ II K+ W E + N
Sbjct: 18499 PPEGPLKV-TGVTAEKCYLAWNPPLQDGGA-NISHYIIEKRETSRLSWTQVSTEVQALNY 18556
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ VT LL Y F + AVN G+ E P + V+ P
Sbjct: 18557 K--------------VTKLLPGNEYIFRVMAVNKYGIGE----PLESGPVTACNPYKPPG 18598
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQE---------TSYTILRA 489
P T + +++S+ ++W P G + E EK+++E + T LR
Sbjct: 18599 PPSTPEVSAITKDSMVVTWARPVDDGGT--EIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18656
Query: 490 RGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
R T +T Y F++ A AAG G S F + D +Y
Sbjct: 18657 RVTGLTEGHS-----YEFRVAAENAAGVGEPSEPSVFYRACDALY 18696
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 31/191 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNI-----ICKKCGWNIKQCEPCSPNVRFLPRQFG 388
++I + SV L W PL GG + + + K +C C
Sbjct: 14572 TDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC------------ 14619
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKD 446
T VT L Y F + A N G+ E + A APSP ++
Sbjct: 14620 ----TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA------SEAPSPPDSLNIM 14669
Query: 447 RTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
+++++SL+W +P+H G I Y ++ K + ++ I +G + +L Y
Sbjct: 14670 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTH-ITTVKGLECVVRNLTEGEEY 14728
Query: 506 VFQIRARTAAG 516
FQ+ A +AG
Sbjct: 14729 TFQVMAVNSAG 14739
Score = 46.2 bits (108), Expect = 8e-05
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 30/219 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ + +L W PLD GG K + I+ K+ + S
Sbjct: 15252 PPEGPL-AVTEVTSEKCVLSWFPPLDDGGAK-IDHYIVQKRETSRLAWTNVASE------ 15303
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T + VT LL Y F + AVN GV E P + V P P
Sbjct: 15304 ----VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE----PLESEPVLAVNPYGPPDPPKN 15355
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVT 495
+ +++S+ + W P+ G I++Y V+ +K Q + + T LR +
Sbjct: 15356 PEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYK----- 15410
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+S L Y F+I A AAG S F + D ++
Sbjct: 15411 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15449
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 24/213 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + L W P D GG K +T I+ K+ + V +
Sbjct: 20663 PPGGPIE-FKTVTAEKITLLWRPPADDGGAK-ITHYIVEKRE----------TSRVVWSM 20710
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
L +T T ++ Y F + AVN G+ E P + +V P P
Sbjct: 20711 VSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE----PLESDSVVAKNAFVTPGPPGI 20766
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS--YTILR--ARGTNVTISS 498
+ + ++NS+++ W P G D + EK+++++ + +L+ R T ++
Sbjct: 20767 PEVTKITKNSMTVVWSRPIADGG--SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTG 20824
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
L ++ Y +++ A AAG G S EF + D
Sbjct: 20825 LTENSDYQYRVCAVNAAGQGPFSEPSEFYKAAD 20857
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
T V DL Y F + AVN GV E P + + T Q AP L +
Sbjct: 22198 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGE----PYEMPEPIVATEQPAPPRRLDVVD-- 22251
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ---ETSYTILRARGTNVTISSLKPDT 503
TS++S L+W +P+H G I Y ++ +K E +T + T+ L T
Sbjct: 22252 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT----KQLTFTVERLVEKT 22307
Query: 504 IYVFQIRARTAAGYGTNSRKF 524
Y F+++A+ AGY F
Sbjct: 22308 EYEFRVKAKNDAGYSEPREAF 22328
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 26/245 (10%)
Query: 298 EDGSMNCRCENNYFRADKDPPS--MACTR---PPSSPRNV-ISNINETSVILDWSWPLDT 351
++ S R N ++ PS + C PPS PR + + NI + + L W+ P
Sbjct: 7746 QEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKD 7805
Query: 352 GGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDA 411
GG +T N I +K K + V+ +T TVT L + Y F + A
Sbjct: 7806 GG-SPIT-NYIVEKRDVRRKGWQTVDTTVK---------DTKCTVTPLTEGSLYVFRVAA 7854
Query: 412 VNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYE 471
N + + + + ++ T P D T R+ + L W+ P++ G +
Sbjct: 7855 ENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQ-- 7911
Query: 472 VKYYEKQEQETSYTILRARGT-----NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+Y ++++ ++A T N ++ + T FQ+RA AG G S E
Sbjct: 7912 -RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEI 7970
Query: 527 ETSPD 531
+ D
Sbjct: 7971 LSIED 7975
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/212 (26%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNVRFLPRQFGL 389
+ ++ + V L W P + GGR + I K+ W +K + P+ F
Sbjct: 7887 VVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW-VKAGKTAGPDCNF------- 7938
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
VTD++ T F++ A N GV S P +SI + PSP L +
Sbjct: 7939 -----RVTDVIEGTEVQFQVRAENEAGVGHPSEPTE---ILSIEDPTSPPSPPLDLHVTD 7990
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKY----YEKQEQETSYTILRARGTNVTISSLKPD 502
R I+++W+ PE G I+ Y V+ EK + S I + + PD
Sbjct: 7991 AGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFK--VEEGVVPD 8048
Query: 503 TIYVFQIRARTAAGYGTNSRKFE--FETSPDC 532
YV ++RA A G S E PDC
Sbjct: 8049 KEYVLRVRAVNAIGVSEPSEISENVVAKDPDC 8080
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 28/218 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP P VIS + L W PL GG + + + ++ W + NV+
Sbjct: 16334 PPEGPV-VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA-----NVQ 16387
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSE-LSSPPRQFAAVSITTNQAAPS 438
L + VT LL YTF I AVN GV E L S P + +
Sbjct: 16388 TL---------SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16438
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG-TNVTI 496
V T+ KD S+ + W+ P G IL Y ++ +K+ + R G + +
Sbjct: 16439 EVTTVTKD-----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16493
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++ A AAG S ++ + D +Y
Sbjct: 16494 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16531
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 21/134 (15%)
Query: 299 DGSMNCRCENNYFRADKDPPSM---ACTR-----PPSSPRNVISNINETSVILDWSWPLD 350
D EN ++ PPS AC PP++P+ + +I +SV L WS P+
Sbjct: 16501 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPK--VIDITRSSVFLSWSKPIY 16558
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG + + I +KC ++ + C+P G+ T + V LL Y F I
Sbjct: 16559 DGGCEIQGY--IVEKCDVSVGEWTMCTPPT-------GINKTNIEVEKLLEKHEYNFRIC 16609
Query: 411 AVN--GVSELSSPP 422
A+N GV E + P
Sbjct: 16610 AINKAGVGEHADVP 16623
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 23/201 (11%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ ++NI + S+ + W+ P D+ G ++ I+ K+ I+ + C+
Sbjct: 17514 PGPPKSLEVTNIAKDSMTVCWNRP-DSDGGSEIIGYIVEKRDRSGIRWIK-CNKR----- 17566
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T+ + VT L Y F + A N GV E S + A P+
Sbjct: 17567 ---RITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17623
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE----TSYTILRARGTNVTIS 497
+ T++NSI+L+W +P + G IL Y V+ + E+E T T LR T IS
Sbjct: 17624 VD---TTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRV--TRFEIS 17678
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y ++ A G G
Sbjct: 17679 KLTEHQEYKIRVCALNKVGLG 17699
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 292 PHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLD 350
P+ ++D C N F D+ + P PR V +S+++ SV L W+ P
Sbjct: 24783 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPAS 24842
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG K N I +KC + R+L R T TV +L T+Y F +
Sbjct: 24843 DGGSK--ITNYIVEKCATTAE---------RWL-RVGQARETRYTVINLFGKTSYQFRVI 24890
Query: 411 AVN--GVSELSSP 421
A N G+S+ S P
Sbjct: 24891 AENKFGLSKPSEP 24903
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P PR++ +S I + S L W PLD GG V N + ++ Q P
Sbjct: 11005 PGPPRDLEVSEIRKDSCYLTWKEPLDDGG--SVITNYVVERRDVASAQWSP--------- 11053
Query: 385 RQFGLTNTTVTVTDLLAHTN----YTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L+ T+ + H N Y F + A N G P+ A+ P
Sbjct: 11054 ----LSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPK 11109
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV--T 495
+ + D+T +SL W +P+ G I Y V+Y QE+ T I TN+
Sbjct: 11110 DLHHVDVDKTE---VSLVWNKPDRDGGSPITGYLVEY---QEEGTQDWIKFKTVTNLECV 11163
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L+ Y F+++A G G
Sbjct: 11164 VTGLQQGKTYRFRVKAENIVGLG 11186
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 26/204 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P RN+ I +++ + W P D GG C+ + +++CE R +
Sbjct: 11992 PGPVRNLKIVDVSSDRCTVCWDPPEDDGG---------CEIQNYILEKCE----TKRMVW 12038
Query: 385 RQFGLTNTT--VTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T T TVT L+ Y F + A N + + PP + V T P
Sbjct: 12039 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG--TGPPTESKPVIAKTKYDKPGRPDP 12096
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGT----NVTIS 497
+ + S+ +++ W PE+ G I Y + EK+E+ ++ + + + +
Sbjct: 12097 PEVTKVSKEEMTVVWNPPEYDGGKSITGY---FLEKKEKHSTRWVPVNKSAIPERRMKVQ 12153
Query: 498 SLKPDTIYVFQIRARTAAGYGTNS 521
+L PD Y F+++A G G S
Sbjct: 12154 NLLPDHEYQFRVKAENEIGIGEPS 12177
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/209 (25%), Positives = 84/209 (40%), Gaps = 33/209 (15%)
Query: 326 PSSPRNVIS--NINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P+SP + +I SV + W P D GG + G+ +++ E P +
Sbjct: 23923 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL---------GYILERREV--PKAAWY 23971
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP---- 439
+ T++ V L + Y F + A N +S P + V+ T P P
Sbjct: 23972 TIDSRVRGTSLVVKGLKENVEYHFRVSAENQFG-ISKPLKSEEPVTPKTPLNPPEPPSNP 24030
Query: 440 --VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG----T 492
VL + K +S+SLSW P+ G + Y Y E++E T + + T
Sbjct: 24031 PEVLDVTK-----SSVSLSWSRPKDDGGSRVTGY---YIERKETSTDKWVRHNKTQITTT 24082
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNS 521
T++ L PD Y F+I A+ G S
Sbjct: 24083 MYTVTGLVPDAEYQFRIIAQNDVGLSETS 24111
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/201 (23%), Positives = 82/201 (40%), Gaps = 34/201 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
S+I ++S L W P GG + + + ++ G ++P G +
Sbjct: 8184 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRT-----------YIPVMSGENKLS 8232
Query: 394 VTVTDLLAHTNYTFEIDAVNGVS-----ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
TV DL+ + Y F + AVN V EL +P V + P P + ++
Sbjct: 8233 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP------VIAQDPKQPPDPPVDVEVHNP 8286
Query: 449 SRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVTISSLKP 501
+ +++++W+ P + G I+ Y ++ K E+ E IL T L+
Sbjct: 8287 TAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL-----TYTAKGLEE 8341
Query: 502 DTIYVFQIRARTAAGYGTNSR 522
Y F++RA AAG SR
Sbjct: 8342 GKEYQFRVRAENAAGISEPSR 8362
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/201 (22%), Positives = 80/201 (39%), Gaps = 25/201 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P NV + I++ S + W P+ GG + + + ++ W+ E CS
Sbjct: 13482 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CS---- 13536
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
T+ V +L +Y F + A N + P AV + P PV+
Sbjct: 13537 ---------KTSFRVANLEEGKSYFFRVFAENEYG-IGDPGETRDAVKASQT---PGPVV 13583
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+K S++S S+ W++P G I+ Y V + E+ ++++ + L
Sbjct: 13584 DLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLT 13641
Query: 501 PDTIYVFQIRARTAAGYGTNS 521
Y F++ A G GT S
Sbjct: 13642 EGKEYTFRVSAENENGEGTPS 13662
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + I++ S+++ W P++ GG + G+++++ E S +
Sbjct: 17120 PPGTP--FATAISKDSMVIQWHEPVNNGGSPVI---------GYHLERKERNSILWTKVN 17168
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T +L Y F + A N GV + S + A P P++
Sbjct: 17169 KTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMV 17227
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
RN I+L W +P + G ++ Y ++ ++A TNV T+S
Sbjct: 17228 ------KRNEITLQWTKPVYDGGSMI---TGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17278
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 17279 GLTEDQRYEFRVIAKNAAG 17297
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P+ + +I + SV L W P D GG +T ++ K+ S
Sbjct: 7183 PSAPKELKFGDITKDSVHLTWEPPDDDGG-SPLTGYVVEKR---------EVSRKTWTKV 7232
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
F +T+ TV DL+ Y F++ A N P V+++T P P +K
Sbjct: 7233 MDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGP-GEPAYVDEPVNMSTPATVPDPPENVK 7290
Query: 445 -KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+DRT+ NSI L+W P++ G I Y V+ + + T + ++ L+
Sbjct: 7291 WRDRTA-NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEG 7349
Query: 503 TIYVFQIRARTAAGYGTNSRKFE 525
Y ++++A G SR E
Sbjct: 7350 KWYAYRVKALNRQGASKPSRPTE 7372
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ +S+I S L W P D GG D + +K + K +P+
Sbjct: 9607 PGPPKDLKVSDITRGSCRLSWKMPDDDGG--DRIKGYVIEKRTIDGKAWTKVNPDCG--- 9661
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+TT V DLL+ Y F + A N + P + P P + +K
Sbjct: 9662 ------STTFVVPDLLSEQQYFFRVRAENRFG-IGPPVETIQRTTARDPIYPPDPPIKLK 9714
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYY------EKQEQETSYTILRARGTNVTIS 497
++N++ LSW+ P++ G + Y V+ K+E T+
Sbjct: 9715 IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9774
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+++A AAG
Sbjct: 9775 DLVEGGEYEFRVKAVNAAG 9793
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 32/201 (15%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP +P V++ + S+ + W+ P+ GG + + +++ K+ W +K + P +
Sbjct: 16038 PPGTP--VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTK 16094
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
F T L Y F + A N G+ + S + A P
Sbjct: 16095 F------------KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEA 16142
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVT 495
++ +RNS++L W++P + G I Y V+ E E + S+T T+
Sbjct: 16143 IIV------TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT--NIIDTHFE 16194
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
++ L D Y F++ AR AAG
Sbjct: 16195 VTGLVEDHRYEFRVIARNAAG 16215
Score = 43.9 bits (102), Expect = 4e-04
Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ S+ L W+ PL TGG + N I +K + S V
Sbjct: 17020 PPKGPVK-FDDVSAESITLSWNPPLYTGGCQ--ITNYIVQKRDTTTTVWDVVSATV---- 17072
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE---LSSPPRQFAAVSITTNQAAPSPVL 441
TT+ VT L T Y F I A N + L S P + P P
Sbjct: 17073 -----ARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP-----IVAQYPYKEPGPPG 17122
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTIS 497
T S++S+ + W EP + G ++ Y ++ E+ + + TI+ T
Sbjct: 17123 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII--HDTQFKAQ 17180
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+L+ Y F++ A G G S+ E + D
Sbjct: 17181 NLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17214
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/193 (23%), Positives = 76/193 (39%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+N+ + + + S L W P+ GG K + I ++ S +
Sbjct: 17811 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----------STRKAYAN 17859
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T+ V +L Y F + A N + P AV PSP +
Sbjct: 17860 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-VGVPVETVDAVKAAE---PPSPPGKVT 17915
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
S+ S SL W++PEH G +L Y V+ K ++ S + ++ N ++ L
Sbjct: 17916 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS-IVAESKVCNAVVTGLSSGQ 17974
Query: 504 IYVFQIRARTAAG 516
Y F+++A G
Sbjct: 17975 EYQFRVKAYNEKG 17987
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/206 (21%), Positives = 81/206 (39%), Gaps = 22/206 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ V++ W P TGG C+ + +++ + + +
Sbjct: 18102 PPVGPVR-FDEVSADFVVISWEPPAYTGG---------CQISNYIVEKRDTTTTTWHMVS 18151
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TT+ +T L T Y F I A N + S P AV + P P T
Sbjct: 18152 AT--VARTTIKITKLKTGTEYQFRIFAENRYGK--SAPLDSKAVIVQYPFKEPGPPGTPF 18207
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTI 504
S++ + + W EP + G + + Y+ +Q+++ S ++ T + + K +
Sbjct: 18208 VTSISKDQMLVQWHEPVNDGGTKI---IGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGL 18264
Query: 505 -----YVFQIRARTAAGYGTNSRKFE 525
Y F++ A G G S+ E
Sbjct: 18265 DEGLEYEFKVSAENIVGIGKPSKVSE 18290
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/235 (20%), Positives = 100/235 (42%), Gaps = 18/235 (7%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+++ED C +N + P ++ P P + I ++ S+ + W+ P GG
Sbjct: 19152 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGG 19211
Query: 354 RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
C+ + +++ E S + + + T++ + L + Y F + A N
Sbjct: 19212 ---------CQISNYIVEKKETTSTTWHIVSQ--AVARTSIKIVRLTTGSEYQFRVCAEN 19260
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEV 472
+ S + +AV + P P T K +++++ ++WQ P + G ++ Y +
Sbjct: 19261 RYGKSSYS--ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL 19318
Query: 473 KYYEKQE--QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+Y E+ + IL A T + +S L +Y +++ A AG G S+ E
Sbjct: 19319 EYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE 19372
Score = 43.9 bits (102), Expect = 4e-04
Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 317 PPSMACTRPPSSPRNVI--SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCE 374
P ++ PPS P+ I I SVIL W P D GG + I C ++I++ E
Sbjct: 21343 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE-----ITC----YSIEKRE 21393
Query: 375 PCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITT 432
N + + + TT V +L+ Y F + A N GVS+ P + +
Sbjct: 21394 TSQTNWKMVCS--SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ----PLVSSIIVAKH 21447
Query: 433 NQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILR 488
P P + + +SL+W P + G + + V+ E+ Q+ + + +
Sbjct: 21448 QFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 21507
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS--RKFEFETSP 530
R T L Y F++ A +AG + S KF SP
Sbjct: 21508 GREYRAT--GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21549
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 30/207 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P I I+ TS+ + W P GG G+ ++Q + P +LP
Sbjct: 23529 PPTGPIK-IDEIDATSITISWEPPELDGG---------APLSGYVVEQRDAHRPG--WLP 23576
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T +T T L Y F + A N G+ Q + ++ P P T
Sbjct: 23577 VSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSIRIPGPPET 23632
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE------QETSYTILRARGTNVT 495
++ SR+ ++L+W PE G + Y V+ E + + T+ R R T +T
Sbjct: 23633 LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLT 23692
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSR 522
Y ++ A A G G SR
Sbjct: 23693 -----EGLEYEHRVTAINARGSGKPSR 23714
Score = 43.1 bits (100), Expect = 6e-04
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P NV I+++N V L W P GG ++T +I + +I+ + L
Sbjct: 6886 PGPPLNVTITDVNRFGVSLTWEPPEYDGGA-EITNYVIELRDKTSIRWDTAMTVRAEDL- 6943
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TVTD++ Y+F + A N + + P V + PSP + +
Sbjct: 6944 --------SATVTDVVEGQEYSFRVRAQNRIG-VGKPSAATPFVKVADPIERPSPPVNLT 6994
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEK-QEQETSYTILRARGTNVTISSLKPD 502
+++S+ L W+ P G IL Y ++ E+ ++ + ++ L+
Sbjct: 6995 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 7054
Query: 503 TIYVFQIRARTAAG 516
Y++++ A AG
Sbjct: 7055 NKYLYRVSAENKAG 7068
Score = 43.1 bits (100), Expect = 6e-04
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 17/97 (17%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNI-ICKKC--GWNIKQCEPCSPNV 380
PP P V +++ ++T+V L+WS P+ GG + + + I +CK W+ E C
Sbjct: 21948 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC---- 22003
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE 417
T TVTDL A Y F + A+NG +
Sbjct: 22004 ---------VKTRYTVTDLQAGEEYKFRVSAINGAGK 22031
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + + +++ W PLD GG K + I K+ G ++ ++P
Sbjct: 10609 PPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDV-----------WMP 10656
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT V+ LL +Y F I A N G+S+ A A P++T
Sbjct: 10657 VTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVT 10716
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W +P I +Y EK+E + R VT + P
Sbjct: 10717 ----EVTKDSALVTWNKPHDGGKPITNY---ILEKRE------TMSKRWARVTKDPIHPY 10763
Query: 503 T-----------IYVFQIRARTAAGYGTNS 521
T Y F++ A G G S
Sbjct: 10764 TKFRVPDLLEGCQYEFRVSAENEIGIGDPS 10793
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 30/204 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNII----CKKCGWNIKQCEPCSPNVRFLPRQFG 388
+S + + L WS P + GG ++T I+ + W I + E P + ++
Sbjct: 22844 VSRVTQEKCTLAWSLPQEDGG-AEITHYIVERRETSRLNWVIVEGE--CPTLSYV----- 22895
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
VT L+ + Y F + AVN P + + + PSP ++ T
Sbjct: 22896 -------VTRLIKNNEYIFRVRAVNKYG--PGVPVESEPIVARNSFTIPSPPGIPEEVGT 22946
Query: 449 SRNSISLSWQEPEHPNG-IILDYEVKYYEKQ-----EQETSYTILRARGTNVTISSLKPD 502
+ I + W +PE G I +Y V EK+ Y + T + ++SL
Sbjct: 22947 GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVY---DTRLKVTSLMEG 23003
Query: 503 TIYVFQIRARTAAGYGTNSRKFEF 526
Y F++ A AAG S F
Sbjct: 23004 CDYQFRVTAVNAAGNSEPSEASNF 23027
Score = 40.4 bits (93), Expect = 0.004
Identities = 47/205 (22%), Positives = 82/205 (40%), Gaps = 34/205 (16%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNV 380
PPS+P R + +++ ++ + W P GG K + + + K+ W + PC
Sbjct: 22535 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC---- 22590
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
VT L+ Y F A+N GVS+ S R A + P
Sbjct: 22591 ---------LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE 22641
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARG 491
+R+++SL W P + G ++ Y ++ E + +YTI+
Sbjct: 22642 VT------DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS--D 22693
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T+++L Y F++ A+ AAG
Sbjct: 22694 NFFTVTALSEGDTYEFRVLAKNAAG 22718
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 16/189 (8%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
SNI S+ L W+ P GG + + + ++ + + V+ + ++ ++ T
Sbjct: 21856 SNITGNSITLTWARPESDGGSEIQQYILERRE--------KKSTRWVKVISKR-PISETR 21906
Query: 394 VTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
VT L Y F + A N GV S R + P P +K TS+
Sbjct: 21907 FKVTGLTEGNEYEFHVMAENAAGVGPASGISR---LIKCREPVNPPGPPTVVKVTDTSKT 21963
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTISSLKPDTIYVFQI 509
++SL W +P G+ I+ Y ++ + + A T T++ L+ Y F++
Sbjct: 21964 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 22023
Query: 510 RARTAAGYG 518
A AG G
Sbjct: 22024 SAINGAGKG 22032
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 28/204 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P+ + + S+++ W+ PLD GG +T G+ +++ E SP +
Sbjct: 9296 PPGKPKVLART--KGSMLVSWTPPLDNGG-SPIT--------GYWLEKREEGSPYWSRVS 9344
Query: 385 R----QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS-- 438
R + GL V LL Y F A+N PP + + + + P
Sbjct: 9345 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG--IGPPSEPSDPEVAGDPIFPPGP 9402
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT-- 495
P KD+T ++SISL W+ P G I Y V+ E E T + + +T
Sbjct: 9403 PSCPEVKDKT-KSSISLGWKPPAKDGGSPIKGYIVEMQE--EGTTDWKRVNEPDKLITTC 9459
Query: 496 ---ISSLKPDTIYVFQIRARTAAG 516
+ +LK Y F+++A AG
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAG 9483
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/197 (23%), Positives = 85/197 (43%), Gaps = 25/197 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP-RQFGLTN 391
++ +++ + + W+ P GG K +T G+ +++ E S R++P + +
Sbjct: 12099 VTKVSKEEMTVVWNPPEYDGG-KSIT--------GYFLEKKEKHS--TRWVPVNKSAIPE 12147
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
+ V +LL Y F + A N G+ E S P R A P P + T+
Sbjct: 12148 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE---PPGPPTNFRVVDTT 12204
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEK---QEQETSYTILRARGTNV----TISSLKP 501
++SI+L W +P + G I+ Y V+ K + + A V T++SL
Sbjct: 12205 KHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDE 12264
Query: 502 DTIYVFQIRARTAAGYG 518
+ Y F++ A+ G G
Sbjct: 12265 NQEYEFRVCAQNQVGIG 12281
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + ++ ++ L W+ PL GG K V ++I E N R++
Sbjct: 21552 PPGTPDYI--DVTRETITLKWNPPLRDGGSKIVGYSI------------EKRQGNERWVR 21597
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
F ++ TVT L Y F I A N V + SPP Q + + +T ++ P
Sbjct: 21598 CNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI-SPPSQSSGIIMTRDENVP 21650
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P V NI +V L W+ P TGG K +T I+ K+ PN R+L
Sbjct: 15054 PPGKP--VPLNITRHTVTLKWAKPEYTGGFK-ITSYIVEKRD----------LPNGRWLK 15100
Query: 385 RQFG-LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + TV+ L Y F + A N +S P A++ + AP + +
Sbjct: 15101 ANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDV 15160
Query: 444 K 444
K
Sbjct: 15161 K 15161
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 329 PRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
PRNV I++I++ SV L W P GG K +T I+ ++ P+ R+ F
Sbjct: 20466 PRNVRITDISKNSVSLSWQQPAFDGGSK-ITGYIVERRD----------LPDGRWTKASF 20514
Query: 388 -GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
+T T ++ L ++ Y F + A N V +S+P ++ + P
Sbjct: 20515 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP 20565
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 27/194 (13%)
Query: 332 VISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTN 391
VI + + S ++ W P D GG N + +KC + ++
Sbjct: 24426 VIEALLKNSAVISWKPPADDGG--SWITNYVVEKC--------EAKEGAEWQLVSSAISV 24475
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQ-----AAPSPVLTIK 444
TT + +L + Y F + A N G+S+ P + ++V I + A P +T
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISD----PLEVSSVVIIKSPFEKPGAPGKPTIT-- 24529
Query: 445 KDRTSRNSISLSWQEPEHPNGIILD--YEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W+ P G + Y K +KQ + S T R T ++ +L
Sbjct: 24530 --AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEG 24587
Query: 503 TIYVFQIRARTAAG 516
Y F+++ G
Sbjct: 24588 LEYEFRVKCENLGG 24601
Score = 38.1 bits (87), Expect = 0.021
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P +P ++ + + S+I+ W P GG + + + ++ K+ I+ R R
Sbjct: 16435 PKAPE--VTTVTKDSMIVVWERPASDGGSEILGY-VLEKRDKEGIRW-------TRCHKR 16484
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
G + VT L+ + +Y F + A N G+SE SPP + + P P
Sbjct: 16485 LIG--ELRLRVTGLIENHDYEFRVSAENAAGLSE-PSPPSAYQKACDPIYK--PGPPNNP 16539
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILR----ARGTNVTI 496
K +R+S+ LSW +P + G E++ Y ++ + S +T+ TN+ +
Sbjct: 16540 KVIDITRSSVFLSWSKPIYDGGC----EIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEV 16595
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNS 521
L Y F+I A AG G ++
Sbjct: 16596 EKLLEKHEYNFRICAINKAGVGEHA 16620
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++NI SV L WS P GG K G+ +++ E P+ R+L
Sbjct: 19382 PPGQPE--VTNITRKSVSLKWSKPHYDGGAKIT---------GYIVERRE--LPDGRWLK 19428
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + T VT+L Y F + A N +S P + + + P ++ +
Sbjct: 19429 CNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDV 19488
Query: 444 K 444
K
Sbjct: 19489 K 19489
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PPS P + V+++I E + + W+ P GG +T G+ +++ E VR
Sbjct: 11398 PPSPPGKPVVTDITENAATVSWTLPKSDGG-SPIT--------GYYMERREVTGKWVRV- 11447
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + VT L Y F + A N ++ LS P + P P +
Sbjct: 11448 -NKTPIADLKFRVTGLYEGNTYEFRVFAEN-LAGLSKPSPSSDPIKACRPIKPPGPPINP 11505
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVK 473
K SR + L W +P G IL Y V+
Sbjct: 11506 KLKDKSRETADLVWTKPLSDGGSPILGYVVE 11536
Score = 37.7 bits (86), Expect = 0.027
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T+T + + + + + + + A N V E+ ++I + P IK D S
Sbjct: 14814 TSTILNINECVRSDSGPYPLTARNIVGEVGD------VITIQVHDIPGPPTGPIKFDEVS 14867
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+ ++ SW PE+ G+ I +Y V+ +Q T++ L T + + T +Q
Sbjct: 14868 SDFVTFSWDPPENDGGVPISNYVVEM--RQTDSTTWVELATTVIRTTYKATRLTTGLEYQ 14925
Query: 509 IRARTAAGYG 518
R + YG
Sbjct: 14926 FRVKAQNRYG 14935
Score = 37.4 bits (85), Expect = 0.035
Identities = 40/200 (20%), Positives = 75/200 (37%), Gaps = 25/200 (12%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNV 380
RP ++N+ + + + W PLD GG + F + +K GW+I + +
Sbjct: 11696 RPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI 11755
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ +LLA+ Y F + A N GV A++ P
Sbjct: 11756 K---------------ANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPE 11800
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTI 496
+ K +T + L W+ P++ G L Y V+ K + + + T+ +
Sbjct: 11801 NLHIADKGKT---FVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMV 11857
Query: 497 SSLKPDTIYVFQIRARTAAG 516
+ IY F+++ + G
Sbjct: 11858 DRCVENQIYEFRVQTKNEGG 11877
Score = 37.4 bits (85), Expect = 0.035
Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 395 TVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T L+ Y F + AVN GV A + T A P + + NS
Sbjct: 21807 TAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP----EPSNITGNS 21862
Query: 453 ISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSLKPDTIYVFQI 509
I+L+W PE G I Y ++ EK+ I + T ++ L Y F +
Sbjct: 21863 ITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21922
Query: 510 RARTAAGYGTNS 521
A AAG G S
Sbjct: 21923 MAENAAGVGPAS 21934
Score = 37.0 bits (84), Expect = 0.046
Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I +V L W P GG K +T I+ KK P+ R++
Sbjct: 18300 PPGRPEAIV--ITRNNVTLKWKKPAYDGGSK-ITGYIVEKKD----------LPDGRWMK 18346
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + T TV+ L+ Y F + A N S P A++ AP+ L
Sbjct: 18347 ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDP 18406
Query: 444 K 444
K
Sbjct: 18407 K 18407
Score = 37.0 bits (84), Expect = 0.046
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T T++++ + T+E+ N ++ P + + P P I+ D S
Sbjct: 19143 TVTSLSIKEASKEDVGTYELCVSNSAGSITVP----ITIIVLDRPGPPGP---IRIDEVS 19195
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+SI++SW PE+ G I +Y V+ +K+ T++ I+ +I ++ T +Q
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVE--KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQ 19253
Query: 509 IRARTAAGYGTNS 521
R YG +S
Sbjct: 19254 FRVCAENRYGKSS 19266
Score = 37.0 bits (84), Expect = 0.046
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 20/201 (9%)
Query: 324 RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRF 382
R P P + I +++ + L W P D GG + VT I+ +K ++ N
Sbjct: 23625 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ-VTGYIVERK---EVRADRWVRVN--- 23677
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAP-SP 439
+ +T T T L Y + A+N G + S P + A+ P +P
Sbjct: 23678 ---KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 23734
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE-TSYTILRARGTNVTIS 497
+T T+R S+SL+W PE G + Y ++ + + E T + T++
Sbjct: 23735 RVT----DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLT 23790
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y F++ A A G G
Sbjct: 23791 HLPQGAEYRFRVLACNAGGPG 23811
Score = 36.6 bits (83), Expect = 0.060
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + NI SV L W+ P GG K +T I+ K+ P+ ++
Sbjct: 13971 PPGKPE--VINITRNSVTLIWTEPKYDGGHK-LTGYIVEKRD----------LPSKSWMK 14017
Query: 385 -RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL-- 441
+ TVTDL+ Y F I A N +S+P + AP+ VL
Sbjct: 14018 ANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDP 14077
Query: 442 TIKKDRT 448
TIK T
Sbjct: 14078 TIKDGLT 14084
Score = 36.2 bits (82), Expect = 0.078
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PV +K ++ S +SW PE+ G + Y V+ E + S + T+
Sbjct: 12394 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12453
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+++L P Y F++ A G G
Sbjct: 12454 VTNLVPGNEYYFRVTAVNEYGPG 12476
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/214 (21%), Positives = 78/214 (36%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P + + S+ L W P GG N I +K + + S V
Sbjct: 15938 PPTGPVKM-DEVTADSITLSWGPPKYDGGSS--INNYIVEKRDTSTTTWQIVSATV---- 15990
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT+ L Y F I A N G S + A +PV+T
Sbjct: 15991 -----ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 16045
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ +SR+S+ + W EP G + Y+ ++++ S ++ T + + K
Sbjct: 16046 L----SSRDSMEVQWNEPISDGG---SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTT 16098
Query: 503 TI-----YVFQIRARTAAGYGTNSRKFEFETSPD 531
+ Y F++ A G G S+ E + D
Sbjct: 16099 GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 16132
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/89 (26%), Positives = 37/89 (41%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTI 496
P P +K SR+S++L+W EP G + + E + +AR T T+
Sbjct: 24817 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTV 24876
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+L T Y F++ A G S E
Sbjct: 24877 INLFGKTSYQFRVIAENKFGLSKPSEPSE 24905
Score = 35.0 bits (79), Expect = 0.17
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ + T++ L+W P GG + V + + + G N + C+ +
Sbjct: 8697 PPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN--EWSRCTEKM-IKV 8753
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
RQ+ TV ++ +Y + AVN E PP + V++ Q P+ L +
Sbjct: 8754 RQY-------TVKEIREGADYKLRVSAVNAAGE--GPPGETQPVTVAEPQEPPAVELDV 8803
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 21/167 (12%)
Query: 305 RCENNYFRADK-DPPSMACTRP---PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
R EN + ++ P M P PS P+N ++ +N+ + + W P GG + +
Sbjct: 12762 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12821
Query: 360 NIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGV-SEL 418
+I +K ++ + VR +T L+ Y+F I A+N S
Sbjct: 12822 -LIERKERNSLLWVKANDTLVR---------STEYPCAGLVEGLEYSFRIYALNKAGSSP 12871
Query: 419 SSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
S P ++ + + V+ + K +++SL W P+H G
Sbjct: 12872 PSKPTEYVTARMPVDPPGKPEVIDVTK-----STVSLIWARPKHDGG 12913
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 25/200 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +I + SV L W P GG K +T I+ KK P R++
Sbjct: 16136 PPGRPEAII--VTRNSVTLQWKKPTYDGGSK-ITGYIVEKKE----------LPEGRWMK 16182
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + +T VT L+ Y F + A N S P A++ P I
Sbjct: 16183 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPP----RI 16238
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYE--KQEQETSYTI-LRARGTNVTISSLK 500
D +++I + E + I + + K +QE S T L + T+ S
Sbjct: 16239 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16298
Query: 501 PDTIYV----FQIRARTAAG 516
D + V + ++A+ AG
Sbjct: 16299 KDAVRVDSGNYILKAKNVAG 16318
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ V + ++++++ W P++ GG + + +++ K+ S +
Sbjct: 19284 PPGTPKVV--HATKSTMLVTWQVPVNDGGSRVIGYHLEYKER----------SSILWSKA 19331
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T + V+ L Y + + A N G+ + S A P
Sbjct: 19332 NKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVT-- 19389
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R S+SL W +P + G I Y V+ E + + +YT ++ T ++
Sbjct: 19390 ----NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE--TYFEVTE 19443
Query: 499 LKPDTIYVFQIRARTAA 515
L D Y F++ AR AA
Sbjct: 19444 LTEDQRYEFRVFARNAA 19460
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 14/127 (11%)
Query: 317 PPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
P + T P+ PR + + + +++S +L W P GG + + + ++ G +
Sbjct: 22232 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSD------ 22285
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
F T TV L+ T Y F + A N S P F++V I Q
Sbjct: 22286 ------FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAG-YSEPREAFSSVIIKEPQI 22338
Query: 436 APSPVLT 442
P+ LT
Sbjct: 22339 EPTADLT 22345
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P IK +++S L+W+ PE G IL Y ++ E + + + T
Sbjct: 8175 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8234
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+ L P+ Y F+++A G G
Sbjct: 8235 VKDLIPNGEYFFRVKAVNKVGGG 8257
Score = 34.3 bits (77), Expect = 0.30
Identities = 39/183 (21%), Positives = 70/183 (38%), Gaps = 18/183 (9%)
Query: 337 NETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTV 396
N +L+WS P D GG ++T II +K +P + +
Sbjct: 8904 NRKMCLLNWSDPEDDGG-SEITGFIIERKDAKMHTWRQPIETE-----------RSKCDI 8951
Query: 397 TDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLS 456
T LL Y F + A N PP + + P+ + ++++I+L
Sbjct: 8952 TGLLEGQEYKFRVIAKNKFG--CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 9009
Query: 457 WQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRART 513
W+EP G + E + ++K + E L T+ + +L +Y F+++A
Sbjct: 9010 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYEFRVKAVN 9068
Query: 514 AAG 516
G
Sbjct: 9069 EIG 9071
Score = 34.3 bits (77), Expect = 0.30
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P ++K SR+S++++W+ P G + +Y V+ E + + T
Sbjct: 23233 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23292
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
IS L T+Y F++ G G
Sbjct: 23293 ISGLVEGTMYYFRVLPENIYGIG 23315
Score = 33.9 bits (76), Expect = 0.39
Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T + + + D L + + I A N +FAA + P PVL +K T+
Sbjct: 8852 TKSELIIKDALRKDHGRYVITATNSCGS------KFAAARVEVFDV-PGPVLDLKPVVTN 8904
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
R L+W +PE G + + + + T + + I+ L Y F++
Sbjct: 8905 RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRV 8964
Query: 510 RARTAAGYG 518
A+ G G
Sbjct: 8965 IAKNKFGCG 8973
Score = 33.9 bits (76), Expect = 0.39
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
++N R R K +M PP P+N +++ TSV L WS P D GG K +
Sbjct: 23703 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23762
Query: 360 NIICKK 365
I +K
Sbjct: 23763 LIEMQK 23768
Score = 33.5 bits (75), Expect = 0.51
Identities = 39/194 (20%), Positives = 79/194 (40%), Gaps = 17/194 (8%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P + ++ SV + W P GG N I +K ++ + +
Sbjct: 23233 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAP--VNNYIVEKREAAMRAFKTVTTKC---- 23286
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T ++ L+ T Y F + N + + P AV ++ P+ + +
Sbjct: 23287 -----SKTLYRISGLVEGTMYYFRVLPEN-IYGIGEPCETSDAVLVSEVPLVPAKLEVVD 23340
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV--TISSLKPD 502
++++++L+W++P + G L V K E ++ + T + T++SL
Sbjct: 23341 ---VTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEG 23397
Query: 503 TIYVFQIRARTAAG 516
Y+F+IRA+ G
Sbjct: 23398 EQYLFRIRAQNEKG 23411
Score = 33.1 bits (74), Expect = 0.66
Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PP+SP R + ++++ LDW P GG G+ I++ P+ +
Sbjct: 8989 PPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQ---------GYIIEKRRHDKPDFERV 9039
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
++ T T+ V +L H Y F + AVN + E S P V I ++ P TI
Sbjct: 9040 NKRLCPT-TSFLVENLDEHQMYEFRVKAVNEIGE--SEPSLPLNVVIQDDEVPP----TI 9092
Query: 444 KKDRTSR-NSISLSWQEPEHPNGIILDYEVKYYEKQEQET 482
K + R ++I + EP H + + E + ET
Sbjct: 9093 KLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNET 9132
Score = 32.7 bits (73), Expect = 0.86
Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 7/129 (5%)
Query: 391 NTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
++ +T+ + L ++I N + AV +T P I +
Sbjct: 11260 SSVLTIKNCLRRDTGEYQITVSNAAGSKT------VAVHLTVLDVPGPPTGPINILDVTP 11313
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+++SWQ P+ G +++Y V+ + ++ + T + I L+ YVF++
Sbjct: 11314 EHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11373
Query: 510 RARTAAGYG 518
RA G G
Sbjct: 11374 RAENKIGVG 11382
Score = 32.7 bits (73), Expect = 0.86
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PVL ++ +++S++L W P G I +Y V+ E + S +
Sbjct: 14563 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14622
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L Y F++ A G G
Sbjct: 14623 VTGLSEGCEYFFRVMAENEYGIG 14645
Score = 32.7 bits (73), Expect = 0.86
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 8/138 (5%)
Query: 392 TTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
TT T L Y F + A N P A + P P T + +++
Sbjct: 14911 TTYKATRLTTGLEYQFRVKAQNRYGV--GPGITSACIVANYPFKVPGPPGTPQVTAVTKD 14968
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISSLKPDTIYVF 507
S+++SW EP G IL Y V+ E+ Q S ++ G S L Y F
Sbjct: 14969 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV--PGNIFKSSGLTDGIAYEF 15026
Query: 508 QIRARTAAGYGTNSRKFE 525
++ A AG S+ E
Sbjct: 15027 RVIAENMAGKSKPSKPSE 15044
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 37/151 (24%)
Query: 318 PSMACT--RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WN-- 369
P AC +PP P N + + + + L W+ PL GG + + + C+K G WN
Sbjct: 11489 PIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRI 11548
Query: 370 -----IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ 424
I+QC V L+ Y F I A N V E PR+
Sbjct: 11549 NKDELIRQC-------------------AFRVPGLIEGNEYRFRIKAANIVGE--GEPRE 11587
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
A I + P V + D T R+ I++
Sbjct: 11588 LAESVIAKDILHPPEV---ELDVTCRDVITV 11615
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 9/99 (9%)
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSY 484
F A + P PV +K S + ++ W PE G E++ Y ++ ET
Sbjct: 11980 FVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGC----EIQNYILEKCETKR 12035
Query: 485 TILRARGTNV-----TISSLKPDTIYVFQIRARTAAGYG 518
+ V T++ L Y+F++RA G G
Sbjct: 12036 MVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 12074
Score = 31.6 bits (70), Expect = 1.9
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P ++ NE + L W+ P+ GG +T I+ K+ P+ R++
Sbjct: 17218 PPGTPEPIMVKRNE--ITLQWTKPVYDGGSM-ITGYIVEKRD----------LPDGRWMK 17264
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
F + T TV+ L Y F + A N +S P
Sbjct: 17265 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKP 17302
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 437 PSPVLT-IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
P PV T + S L+W PE G I +Y ++ E + +YT+ R
Sbjct: 10311 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ-- 10368
Query: 492 TNVTISSLKPDTIYVFQIRARTAAGYG 518
N T+ L Y F+I A + G G
Sbjct: 10369 -NATVQGLIQGKAYFFRIAAENSIGMG 10394
Score = 30.4 bits (67), Expect = 4.3
Identities = 23/99 (23%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P +K +R S LSW+ P+ G I Y ++ + + T
Sbjct: 9607 PGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFV 9666
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++RA G G + T+ D +Y
Sbjct: 9667 VPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9705
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 426 AAVSITTNQAAPSPV-LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETS 483
A V++ + +PV LTI++ ++S++LSW+ P G I +Y V+ E + +
Sbjct: 18884 AFVNVRVLDSPSAPVNLTIRE--VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18941
Query: 484 YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
T I +L+ Y F++ A G G
Sbjct: 18942 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 18976
Score = 29.6 bits (65), Expect = 7.3
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILRARGT 492
+P P + R ++ +L+W P+ G E+ +Y + +ETS + I+
Sbjct: 22835 SPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA----EITHYIVERRETSRLNWVIVEGECP 22890
Query: 493 NVT--ISSLKPDTIYVFQIRARTAAGYG 518
++ ++ L + Y+F++RA G G
Sbjct: 22891 TLSYVVTRLIKNNEYIFRVRAVNKYGPG 22918
Score = 29.6 bits (65), Expect = 7.3
Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 9/128 (7%)
Query: 393 TVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T+ T + YT E+ V G + + + P IK D S
Sbjct: 23492 TIRETTIRDTGEYTLELKNVTGTTS--------ETIKVIILDKPGPPTGPIKIDEIDATS 23543
Query: 453 ISLSWQEPEHPNGIILD-YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
I++SW+ PE G L Y V+ + + + L YVF++ A
Sbjct: 23544 ITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAA 23603
Query: 512 RTAAGYGT 519
G G+
Sbjct: 23604 TNRFGIGS 23611
Score = 29.6 bits (65), Expect = 7.3
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
+P + + I+ + + S ++ W P GG K + + ++ N K + +R
Sbjct: 24519 KPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQN-KWISVTTEEIR-- 24575
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVL 441
T +V +L+ Y F + N G SE S + IT P
Sbjct: 24576 -------ETVFSVKNLIEGLEYEFRVKCENLGGESEWSE-----ISEPITPKSDVPIQAP 24623
Query: 442 TIKKDRTSRN-----SISLSWQEPEHPNGIILDYEVKYYEKQEQETS----YTILRARGT 492
K++ + N + +L + HP I VK+Y + ++ + Y I +G
Sbjct: 24624 HFKEELRNLNVRYQSNATLVCKVTGHPKPI-----VKWYRQGKEIIADGLKYRIQEFKGG 24678
Query: 493 --NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFE 527
+ I+S+ D V+Q+RA G + + E E
Sbjct: 24679 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24715
Score = 29.3 bits (64), Expect = 9.5
Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 20/158 (12%)
Query: 286 KCAKCPPHSSTQEDGS---MNCRCENNYFRADKDPPS--MACTRPPSSPRNV-ISNINET 339
KC KC + +G EN Y + + + + PS P ++ I +I ++
Sbjct: 14615 KCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKS 14674
Query: 340 SVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDL 399
+V L W P GG K + I ++ G S + GL V +L
Sbjct: 14675 TVSLAWPKPKHDGGSKITGYVIEAQRKG---------SDQWTHITTVKGL---ECVVRNL 14722
Query: 400 LAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
YTF++ AVN S PR+ V + P
Sbjct: 14723 TEGEEYTFQVMAVNSAGR--SAPRESRPVIVKEQTMLP 14758
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 63.2 bits (152), Expect = 6e-10
Identities = 58/199 (29%), Positives = 91/199 (45%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PPS+P +S I + S+++ W+ P+D GG ++ I+ K+ ++ + C+
Sbjct: 18532 PPSTPE--VSAITKDSMVVTWARPVDDGGT-EIEGYILEKRDKEGVRWTK-CNKKT---- 18583
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ + VT L +Y F + A N GV E S P + A P P
Sbjct: 18584 ----LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY---PPGPPSN 18636
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
K TSR+S+SL+W +P + G + EVK E T +G T++ L
Sbjct: 18637 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKL 18696
Query: 500 KPDTIYVFQIRARTAAGYG 518
K +T Y F+I A + G G
Sbjct: 18697 KENTEYNFRICAINSEGVG 18715
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 30/205 (14%)
Query: 324 RPPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSP 378
R P +P + +++ + + S ++ W+ P D G K +T I+ K+ W +P P
Sbjct: 10638 RVPDAPDQPIVTEVTKDSALVTWNKPHDGG--KPITNYILEKRETMSKRWARVTKDPIHP 10695
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQ-FAAVSITTNQA 435
+F V DLL Y F + A N G+ + S P + FA I A
Sbjct: 10696 YTKF------------RVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI----A 10739
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
PSP + + T+ NS+ L+WQ P H G IL Y V+Y + ++E ++T
Sbjct: 10740 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 10799
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T ++ L+ Y F++ A AAG
Sbjct: 10800 TKYKVTGLRDGQTYKFRVLAVNAAG 10824
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I + S+ + WS P+ GG D++ + K+ ++ + +R
Sbjct: 20696 PPGIPE--VTKITKNSMTVVWSRPIADGG-SDISGYFLEKRDKKSLGWFKVLKETIR--- 20749
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T VT L +++Y + + AVN G S P + A P P
Sbjct: 20750 ------DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID---PPGPPAK 20800
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
I+ ++++SI+L W +P + G + E++ E++E T T R T +S+L
Sbjct: 20801 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20860
Query: 500 KPDTIYVFQIRARTAAGYG 518
KP Y F++ A AG G
Sbjct: 20861 KPGVNYYFRVSAVNCAGQG 20879
Score = 59.3 bits (142), Expect = 9e-09
Identities = 66/205 (32%), Positives = 94/205 (45%), Gaps = 36/205 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PPS+P V+ ++ ++SV L WS P D GG + VT G+ I++ E + VR
Sbjct: 23959 PPSNPPEVL-DVTKSSVSLSWSRPKDDGGSR-VT--------GYYIERKETSTDKWVRHN 24008
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELS--SPPRQFAAVSITTNQAAPSP 439
Q +T T TVT L+ Y F I A N G+SE S S P +Q
Sbjct: 24009 KTQ--ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKY-------YEKQEQETSYTILRARG 491
+L+I KD S++L W++PE G IL Y V+Y ++K +E R +
Sbjct: 24067 ILSISKD-----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE------RIKD 24115
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
TI L T Y F++ A G
Sbjct: 24116 KQFTIGGLLEATEYEFRVFAENETG 24140
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 316 DPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
DPP PP P + ++ +TSV L+W+ P GG K ++ I K G +
Sbjct: 7610 DPPW-----PPGKP--TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTD------ 7656
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
++ G+ T + L+ Y+F + AVN E S P V
Sbjct: 7657 -----EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGE-SEPSEPSDPVLCREKLY 7710
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV 494
PSP ++ ++N+ L W PE G I +Y V+ + + + + T
Sbjct: 7711 PPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7770
Query: 495 TISSLKPDTIYVFQIRARTAAG 516
T++ L ++YVF++ A A G
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIG 7792
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 28/243 (11%)
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRN-VISNINETSVILDWSWPLDTGGRKD 356
+ G + EN++ A K P +++ P P N V +I +TSV+ W PLD GG +
Sbjct: 8403 DHGLYMIKVENDHGIA-KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8461
Query: 357 VTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVS 416
+ + +++ + P+ ++ L + +VT L+ Y F + A N
Sbjct: 8462 INY---------TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN--- 8509
Query: 417 ELSSPPRQFAAVSITTNQAAP--SPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY 474
P + + + P +P I +D TS NS+ + W EP+ IL Y +
Sbjct: 8510 RFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS-NSMLVKWNEPKDNGSPILGY---W 8565
Query: 475 YEKQEQETSY------TILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
EK+E +++ ++L A NV L YVF++ A AAG G S + +T
Sbjct: 8566 LEKREVNSTHWSRVNKSLLNALKANV--DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKT 8623
Query: 529 SPD 531
+ D
Sbjct: 8624 AHD 8626
Score = 56.2 bits (134), Expect = 7e-08
Identities = 60/223 (26%), Positives = 88/223 (39%), Gaps = 19/223 (8%)
Query: 307 ENNYFRADKDPPSMACTRPPSSPRN-----VISNINETSVILDWSWPLDTGGRKDVTFNI 361
EN Y D A + P P VISNI + + + W P D GG +T
Sbjct: 13093 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGG-SPIT--- 13148
Query: 362 ICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
G+ +++ E + N + R+ + T+ T L T Y F + A+N P
Sbjct: 13149 -----GYLLEKRETQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGP-GKP 13201
Query: 422 PRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDY--EVKYYEKQ 478
A Q P P K T+R+S+SLSW +P + G I+ Y EVK +
Sbjct: 13202 SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSD 13261
Query: 479 EQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS 521
+ T ++ L DT Y F++ A GY S
Sbjct: 13262 NWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13304
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/190 (25%), Positives = 89/190 (46%), Gaps = 22/190 (11%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S++ +TS + W+ P + GG + VT I+ K+ + K +P V+ T
Sbjct: 12335 VSDVTKTSCHVSWAPPENDGGSQ-VTHYIVEKREA-DRKTWSTVTPEVK---------KT 12383
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT+L+ Y F + AVN G + P+ A + + P P ++ ++
Sbjct: 12384 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA---SDPLSEPDPPRKLEVTEMTK 12440
Query: 451 NSISLSWQEPEHPNGIILDYEVKYYEKQEQE----TSYTILRARGTNVTISSLKPDTIYV 506
NS +L+W P G +D + Y ++EQ T Y+++ + ++ ++ LK Y
Sbjct: 12441 NSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV--KDLSLVVTGLKEGKKYK 12498
Query: 507 FQIRARTAAG 516
F++ AR A G
Sbjct: 12499 FRVAARNAVG 12508
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/222 (26%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L WS PL GG D++ ++ K+ W + E
Sbjct: 17349 PPEGPVQV-TGVTSEKCSLTWSPPLQDGG-SDISHYVVEKRETSRLAWTVVASE------ 17400
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ ++ VT LL Y F I AVN GV E P + A V + P
Sbjct: 17401 --------VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE----PLESAPVLMKNPFVLPG 17448
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTN 493
P +++ +++S+++ W P+ G I+ Y V EK+++ I R
Sbjct: 17449 PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV---EKRDRSGIRWIKCNKRRITDLR 17505
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYY 535
+ ++ L D Y F++ A AAG G E SP +YY
Sbjct: 17506 LRVTGLTEDHEYEFRVSAENAAGVG--------EPSPATVYY 17539
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 319 SMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSP 378
S PP P V + +I+ W+ P GG +++ ++ K+ E S
Sbjct: 22864 SFTIPSPPGIPEEV--GTGKEHIIIQWTKPESDGGN-EISNYLVDKR--------EKKSL 22912
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
+ + + + +T + VT L+ +Y F + AVN S P +S P
Sbjct: 22913 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN-SEPSEASNFISCREPSYTPG 22971
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE--TSYTILRARGTNVT 495
P + T+++SISL+W +P + G I+ Y ++ EK + +T R T T
Sbjct: 22972 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 23031
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
+ LK Y F++ A G
Sbjct: 23032 VPDLKMGQKYSFRVAAVNVKG 23052
Score = 55.5 bits (132), Expect = 1e-07
Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 29/237 (12%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTR-------PPSSPRNVISNINETSVILDWSW 347
+T E+ + EN + +D + + PPS+P ++N+ S+ + W
Sbjct: 20263 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPW--VTNVTRESITVGWHE 20320
Query: 348 PLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTF 407
P+ GG V +++ K + Q + + T VT + A Y F
Sbjct: 20321 PVSNGGSAVVGYHLEMKDRNSILWQ----------KANKLVIRTTHFKVTTISAGLIYEF 20370
Query: 408 EIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
+ A N GV + S P A+ A P ++ S+NS+SLSWQ+P G
Sbjct: 20371 RVYAENAAGVGKPSHPSEPVLAID------ACEPPRNVRITDISKNSVSLSWQQPAFDGG 20424
Query: 466 I-ILDYEVKYYEKQE-QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTN 520
I Y V+ + + + T + T IS L ++ Y F++ AR A G +N
Sbjct: 20425 SKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISN 20481
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 24/207 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P VIS+I E SV L W P GG + VT I+ K+ E + R
Sbjct: 20200 PPTGPV-VISDITEESVTLKWEPPKYDGGSQ-VTNYILLKRETSTAVWTEVSATVAR--- 20254
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
T + V L Y F I A N G+S+ A V++ P P T
Sbjct: 20255 -------TMMKVMKLTTGEEYQFRIKAENRFGISDHIDS----ACVTVKLPYTTPGPPST 20303
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R SI++ W EP G ++ Y ++ ++ Q+ + ++R T+ +++
Sbjct: 20304 PWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT--THFKVTT 20361
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFE 525
+ IY F++ A AAG G S E
Sbjct: 20362 ISAGLIYEFRVYAENAAGVGKPSHPSE 20388
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 24/196 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P N+ + ++ + S +L W P + GG ++I K W + C+
Sbjct: 19906 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW-VSVTNNCN---- 19960
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
+ VT+L Y F + N + P V IT PSP
Sbjct: 19961 ---------RLSYKVTNLQEGAIYYFRVSGENEFG-VGIPAETKEGVKITEK---PSPPE 20007
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ S++S+SL+W +PEH G I+ Y V+ EK Q+ A+ T+ +S L+
Sbjct: 20008 KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEK-GQKNWVKCAVAKSTHHVVSGLR 20066
Query: 501 PDTIYVFQIRARTAAG 516
++ Y F++ A AG
Sbjct: 20067 ENSEYFFRVFAENQAG 20082
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/193 (26%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ + + +TSV L W PL GG K N I +K K + N
Sbjct: 15580 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSK--IKNYIVEKRESTRKAYSTVATNCH--- 15634
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T+ V L +Y F + A N + P +V + P + +
Sbjct: 15635 ------KTSWKVDQLQEGCSYYFRVLAENEYG-IGLPAETAESVKASERPLPPGKITLMD 15687
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RNS+SLSW++PEH G IL Y V+ K + + T + T TI+ L
Sbjct: 15688 ---VTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA-TCATVKVTEATITGLIQGE 15743
Query: 504 IYVFQIRARTAAG 516
Y F++ A+ G
Sbjct: 15744 EYSFRVSAQNEKG 15756
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 26/197 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS P N+ ++ I + SV + W PL GG K N I +K K N
Sbjct: 16662 PSPPVNLKVTEITKDSVSITWEPPLLDGGSK--IKNYIVEKREATRKSYAAVVTNCH--- 16716
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN----GVSELSSPPRQFAAVSITTNQAAPSPV 440
+ + L +Y F + A N G+ ++ P + A V P P
Sbjct: 16717 ------KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV--------PQPP 16762
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSL 499
I D +RNS+SLSW +PEH G I+ Y V+ K ++ S R + I++L
Sbjct: 16763 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWS-ECARVKSLQAVITNL 16821
Query: 500 KPDTIYVFQIRARTAAG 516
Y+F++ A G
Sbjct: 16822 TQGEEYLFRVVAVNEKG 16838
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/202 (26%), Positives = 93/202 (46%), Gaps = 26/202 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PP P +SN+ + + + W P+D GG ++T G+++++ E S VR +
Sbjct: 14202 PPEKPE--VSNVTKNTATVSWKRPVDDGG-SEIT--------GYHVERREKKSLRWVRAI 14250
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA--PSPVL 441
+ +++ VT L + Y F + A N PP + A+ S+ AA P P
Sbjct: 14251 --KTPVSDLRCKVTGLQEGSTYEFRVSAENRAG--IGPPSE-ASDSVLMKDAAYPPGPPS 14305
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ----ETSYTILRARGTNVTI 496
T++ S SL+W +P + G+ I Y V++ + ++ +T+ T LR T +
Sbjct: 14306 NPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI--TQFVV 14363
Query: 497 SSLKPDTIYVFQIRARTAAGYG 518
L+ Y F+I A AG G
Sbjct: 14364 PDLQTKEKYNFRISAINDAGVG 14385
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P VI N+ + L W P+ GG + F++ K+ + Q SP
Sbjct: 21387 PPGKP--VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSP------ 21438
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
++ T L+ +Y F + A N G+S S P + AVS P +
Sbjct: 21439 ----ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI-- 21492
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+R +I+L W P G I+ Y ++ + E+ T++ L P
Sbjct: 21493 ----DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSP 21548
Query: 502 DTIYVFQIRARTAAG 516
Y F+I AR A G
Sbjct: 21549 GDRYEFRIIARNAVG 21563
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P N+ I + + SV L W PL GG K N I +K K + N
Sbjct: 18827 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKIT--NYIVEKRETTRKAYATITNNC---- 18880
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T TT + +L +Y F + A N + P V ++ P V +
Sbjct: 18881 -----TKTTFRIENLQEGCSYYFRVLASNEYG-IGLPAETTEPVKVSEPPLPPGRVTLVD 18934
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RN+ ++ W++PE G I Y V+ K ++ S T + + TIS L
Sbjct: 18935 ---VTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-TCTQVKTLEATISGLTAGE 18990
Query: 504 IYVFQIRARTAAG 516
YVF++ A G
Sbjct: 18991 EYVFRVAAVNEKG 19003
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/217 (24%), Positives = 85/217 (39%), Gaps = 39/217 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP+ P I+ + L W P + GG D+ + I+ K+ W I + E
Sbjct: 19513 PPAGPLE-INGLTAEKCSLSWGRPQEDGGA-DIDYYIVEKRETSHLAWTICEGE------ 19564
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L T+ VT LL Y F + VN GV E P + A+ PS
Sbjct: 19565 --------LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE----PLESVAIKALDPFTVPS 19612
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRAR-----GTN 493
P +++ ++ S++L W PE G + Y ++ ++ S +R
Sbjct: 19613 PPTSLEITSVTKESMTLCWSRPESDGGSEIS---GYIIERREKNSLRWVRVNKKPVYDLR 19669
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
V + L+ Y +++ A AAG S ETSP
Sbjct: 19670 VKSTGLREGCEYEYRVYAENAAGLSLPS-----ETSP 19701
Score = 49.3 bits (116), Expect = 9e-06
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S+++ S +L W P D GG + + + ++ G Q S + T
Sbjct: 22378 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-----------VKRT 22426
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT L + Y+F + + N GVS+ P + A + PS + S
Sbjct: 22427 QIKVTHLTKYMEYSFRVSSENRFGVSK----PLESAPIIAEHPFVPPSAPTRPEVYHVSA 22482
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRAR----GTNVTISSLKPDTIY 505
N++S+ W+EP H G I+ Y + EK+E+ T + + N ++ L Y
Sbjct: 22483 NAMSIRWEEPYHDGGSKIIGY---WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEY 22539
Query: 506 VFQIRARTAAG 516
F+ A AAG
Sbjct: 22540 QFRTYALNAAG 22550
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 20/201 (9%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL- 383
P + + +S++ S+ ++W P GG VT G+ ++ + S + +
Sbjct: 9945 PGAPDKPTVSSVTRNSMTVNWEEPEYDGG-SPVT--------GYWLEMKDTTSKRWKRVN 9995
Query: 384 --PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
P + + VT L+ ++Y F + A+N GV S P A P P
Sbjct: 9996 RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP 10055
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSY-TILRARGTNVTIS 497
+T +++S L W P G + Y V+Y E+ ++E RGT + ++
Sbjct: 10056 KVT----DWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 10111
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
LK Y F++RA AG G
Sbjct: 10112 GLKEGAFYKFRVRAVNIAGIG 10132
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + IS+I+ + L W PL+ GG ++T N I +KC ++ + + ++
Sbjct: 12622 PPQPPFD-ISDIDADACSLSWHIPLEDGG-SNIT-NYIVEKC--DVSRGD-------WVT 12669
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T T+ V L+ Y F + A N G+SE + P+ A PS
Sbjct: 12670 ALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF----GVPSEPKN 12725
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRA-----RGTNVTIS 497
+ + +++ I ++W P+ G + + Y ++++ S ++A R T +
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPI---IGYLIERKERNSLLWVKANDTLVRSTEYPCA 12782
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETS 529
L Y F+I A AG S+ E+ T+
Sbjct: 12783 GLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA 12814
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICK-KCGWNIKQCEPCSPNVRF 382
PP P+N ++ I + S+++ W P GG + + + + + K G +C +
Sbjct: 15282 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT----- 15336
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ V+ L Y F I A N +S+P P P
Sbjct: 15337 ------LTDLRYKVSGLTEGHEYEFRIMAENAAG-ISAPSPTSPFYKACDTVFKPGPPGN 15389
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSL 499
+ TSR+SIS++W +P + G I Y V+ +E E A + T+ TI+ L
Sbjct: 15390 PRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGL 15449
Query: 500 KPDTIYVFQIRARTAAGYG 518
+ Y +I A + G G
Sbjct: 15450 TENQEYKIRIYAMNSEGLG 15468
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 26/210 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIK--QCEPCSPN 379
P RN+ ++ + V L W PL GG K + + + K+ W + + E C
Sbjct: 6718 PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6777
Query: 380 VRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP 439
V L + Y F + A N V P V + P P
Sbjct: 6778 VTGLQK---------------GGVEYLFRVSARNRVGT-GEPVETDNPVEARSKYDVPGP 6821
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQ--EQETSYTILRARGTNVTI 496
L + +R +SL+W+ PE+ G I +Y ++ +K +T+ T+ RA + T+
Sbjct: 6822 PLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTV-RAEDLSATV 6880
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+ + Y F++RA+ G G S F
Sbjct: 6881 TDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6910
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/261 (23%), Positives = 95/261 (36%), Gaps = 38/261 (14%)
Query: 287 CAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP--PSSPRNVISNINETSVILD 344
C P S + G NN A K+ RP P P +++ + L
Sbjct: 9807 CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIK-FESVSADQMTLS 9865
Query: 345 WSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLA 401
W P D GG K + I ++ W EP T T+ LL
Sbjct: 9866 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP--------------KECTYTIPKLLE 9911
Query: 402 HTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQE 459
Y F I A N G+ E + A + A P ++ +RNS++++W+E
Sbjct: 9912 GHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVS----SVTRNSMTVNWEE 9967
Query: 460 PEHPNGIILDYEVKYYEKQEQETSYTILRAR---------GTNVTISSLKPDTIYVFQIR 510
PE+ G + Y+ + + TS R G + ++ L + Y F++
Sbjct: 9968 PEYDGGSPV---TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVY 10024
Query: 511 ARTAAGYGTNSRKFEFETSPD 531
A AAG G S + T+ D
Sbjct: 10025 AINAAGVGPASLPSDPATARD 10045
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/199 (24%), Positives = 89/199 (44%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P +++I++ +++ W P++ GG K + G++++Q E S L
Sbjct: 18135 PPGTP--FVTSISKDQMLVQWHEPVNDGGTKII---------GYHLEQKEKNSILWVKLN 18183
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T T L Y F++ A N G+ + S F A P ++
Sbjct: 18184 KT-PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18242
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RN+++L W++P + G + Y +++ ++A TNV T+S
Sbjct: 18243 ------TRNNVTLKWKKPAYDGGSKI---TGYIVEKKDLPDGRWMKASFTNVLETEFTVS 18293
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ AR AAG
Sbjct: 18294 GLVEDQRYEFRVIARNAAG 18312
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 15/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PS P ++ I+++ + S+ L WS P GG + G+ I++ E S VR
Sbjct: 19611 PSPPTSLEITSVTKESMTLCWSRPESDGGSEI---------SGYIIERREKNSLRWVRVN 19661
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + V T L Y + + A N LS P + PSP
Sbjct: 19662 KKP--VYDLRVKSTGLREGCEYEYRVYAENAAG-LSLPSETSPLIRAEDPVFLPSPPSKP 19718
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
K + + +I+++W +P G I Y V+Y + + + +I RGT TIS L
Sbjct: 19719 KIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTG 19778
Query: 503 TIYVFQIRARTAAG 516
YVF++++ G
Sbjct: 19779 AEYVFRVKSVNKVG 19792
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 29/222 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS PRN+ +++I S L W PLD GG ++T +I K+ + K+ E +
Sbjct: 9126 PSPPRNLAVTDIKAESCYLTWDAPLDNGG-SEITHYVIDKRDA-SRKKAEWEEVTNTAVE 9183
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+++G + L+ + Y F + AVN G+S+ + V I P P
Sbjct: 9184 KRYG-------IWKLIPNGQYEFRVRAVNKYGISDECKSDK----VVIQDPYRLPGPPGK 9232
Query: 443 IKKDRTSRNSISLSWQEP-EHPNGIILDYEVKYYEKQEQETSY---------TILRARGT 492
K ++ S+ +SW P ++ I Y + EK+E+ + Y T + +G
Sbjct: 9233 PKVLARTKGSMLVSWTPPLDNGGSPITGY---WLEKREEGSPYWSRVSRAPITKVGLKGV 9289
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L Y F+ A AAG G S + E + D ++
Sbjct: 9290 EFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIF 9331
Score = 47.8 bits (112), Expect = 3e-05
Identities = 53/254 (20%), Positives = 92/254 (36%), Gaps = 38/254 (14%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+T++D N F + + P P V ISN++ L W+ PL+ GG
Sbjct: 14070 ATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGG 14129
Query: 354 --------RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNY 405
K T ++ +I+ C T L+ Y
Sbjct: 14130 SPIKSYILEKRETSRLLWTVVSEDIQSCRH-------------------VATKLIQGNEY 14170
Query: 406 TFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
F + AVN + P Q V + P P + ++N+ ++SW+ P G
Sbjct: 14171 IFRVSAVNHYGK--GEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGG 14228
Query: 466 IILDYEVKYYEKQEQETSYTILRARGTNVT-----ISSLKPDTIYVFQIRARTAAGYGTN 520
+ Y+ ++ ++ S +RA T V+ ++ L+ + Y F++ A AG G
Sbjct: 14229 SEI---TGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPP 14285
Query: 521 SRKFEFETSPDCMY 534
S + D Y
Sbjct: 14286 SEASDSVLMKDAAY 14299
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/198 (22%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICK---KCGWNIKQCEPCSPNVR 381
P + + + +++ +V L W PL GG + + I + K W++ CS
Sbjct: 20994 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVS-HKCS---- 21048
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
+T+ + DL T + F + A N G+ E A + P+P
Sbjct: 21049 ---------STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV------PAP 21093
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
+ + +++ S+ LSW +P+ G +I +Y V+ K EQ S+ + ++ + +S
Sbjct: 21094 IRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI-SKTCEIEVSQ 21152
Query: 499 LKPDTIYVFQIRARTAAG 516
LK ++ F++ A+ G
Sbjct: 21153 LKEQSVLEFRVFAKNEKG 21170
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P + P I ++ SV L W+ P TGG +++ K+ + + +P +R
Sbjct: 13804 PDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTP-IRM-- 13860
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
R F VT L Y F + A+N GV + S P A+ P +
Sbjct: 13861 RDF-------KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVI-- 13911
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RNS++L W EP++ G L Y ++ S + ++A NV T++
Sbjct: 13912 ----NITRNSVTLIWTEPKYDGGHKL---TGYIVEKRDLPSKSWMKANHVNVPECAFTVT 13964
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+IRA+ AG
Sbjct: 13965 DLVEGGKYEFRIRAKNTAG 13983
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 25/200 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
I+++ S +L W+ P D GG K N + ++ + + S V+ +T
Sbjct: 7420 ITDVTNESCLLTWNPPRDDGGSK--ITNYVVERRATDSEVWHKLSSTVK---------DT 7468
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
T L+ + Y F + A N GV E P Q + ++ P P ++ ++
Sbjct: 7469 NFKATKLIPNKEYIFRVAAENMYGVGE----PVQASPITAKYQFDPPGPPTRLEPSDITK 7524
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTNVTISSLKPDTIY 505
++++L+W EP+ G I Y + E+ + +T + + + T + L Y
Sbjct: 7525 DAVTLTWCEPDDDGGSPITGY---WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKY 7581
Query: 506 VFQIRARTAAGYGTNSRKFE 525
F++ A AG G S+ E
Sbjct: 7582 RFRVLAENLAGPGKPSKSTE 7601
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ ++ + + S+ + W PL GG + +++ K+ + Q + +
Sbjct: 14889 PPGTPQ--VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14946
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ GLT+ Y F + A N G S+ S P A+ P P+
Sbjct: 14947 KSSGLTDGIA----------YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL-- 14994
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+R++++L W +PE+ G + Y ++ + L+A +N+ T+S
Sbjct: 14995 ----NITRHTVTLKWAKPEYTGGFKI---TSYIVEKRDLPNGRWLKANFSNILENEFTVS 15047
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 15048 GLTEDAAYEFRVIAKNAAG 15066
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 42/225 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L W+ PL GG +++ II K+ W E + N
Sbjct: 18432 PPEGPLKV-TGVTAEKCYLAWNPPLQDGGA-NISHYIIEKRETSRLSWTQVSTEVQALNY 18489
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ VT LL Y F + AVN G+ E P + V+ P
Sbjct: 18490 K--------------VTKLLPGNEYIFRVMAVNKYGIGE----PLESGPVTACNPYKPPG 18531
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQE---------TSYTILRA 489
P T + +++S+ ++W P G + E EK+++E + T LR
Sbjct: 18532 PPSTPEVSAITKDSMVVTWARPVDDGGT--EIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18589
Query: 490 RGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
R T +T Y F++ A AAG G S F + D +Y
Sbjct: 18590 RVTGLTEGHS-----YEFRVAAENAAGVGEPSEPSVFYRACDALY 18629
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 31/191 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNI-----ICKKCGWNIKQCEPCSPNVRFLPRQFG 388
++I + SV L W PL GG + + + K +C C
Sbjct: 14505 TDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC------------ 14552
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKD 446
T VT L Y F + A N G+ E + A APSP ++
Sbjct: 14553 ----TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA------SEAPSPPDSLNIM 14602
Query: 447 RTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
+++++SL+W +P+H G I Y ++ K + ++ I +G + +L Y
Sbjct: 14603 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTH-ITTVKGLECVVRNLTEGEEY 14661
Query: 506 VFQIRARTAAG 516
FQ+ A +AG
Sbjct: 14662 TFQVMAVNSAG 14672
Score = 46.2 bits (108), Expect = 8e-05
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 30/219 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ + +L W PLD GG K + I+ K+ + S
Sbjct: 15185 PPEGPL-AVTEVTSEKCVLSWFPPLDDGGAK-IDHYIVQKRETSRLAWTNVASE------ 15236
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T + VT LL Y F + AVN GV E P + V P P
Sbjct: 15237 ----VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE----PLESEPVLAVNPYGPPDPPKN 15288
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVT 495
+ +++S+ + W P+ G I++Y V+ +K Q + + T LR +
Sbjct: 15289 PEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYK----- 15343
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+S L Y F+I A AAG S F + D ++
Sbjct: 15344 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15382
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 24/213 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + L W P D GG K +T I+ K+ + V +
Sbjct: 20596 PPGGPIE-FKTVTAEKITLLWRPPADDGGAK-ITHYIVEKRE----------TSRVVWSM 20643
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
L +T T ++ Y F + AVN G+ E P + +V P P
Sbjct: 20644 VSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE----PLESDSVVAKNAFVTPGPPGI 20699
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS--YTILR--ARGTNVTISS 498
+ + ++NS+++ W P G D + EK+++++ + +L+ R T ++
Sbjct: 20700 PEVTKITKNSMTVVWSRPIADGG--SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTG 20757
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
L ++ Y +++ A AAG G S EF + D
Sbjct: 20758 LTENSDYQYRVCAVNAAGQGPFSEPSEFYKAAD 20790
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
T V DL Y F + AVN GV E P + + T Q AP L +
Sbjct: 22131 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGE----PYEMPEPIVATEQPAPPRRLDVVD-- 22184
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ---ETSYTILRARGTNVTISSLKPDT 503
TS++S L+W +P+H G I Y ++ +K E +T + T+ L T
Sbjct: 22185 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT----KQLTFTVERLVEKT 22240
Query: 504 IYVFQIRARTAAGYGTNSRKF 524
Y F+++A+ AGY F
Sbjct: 22241 EYEFRVKAKNDAGYSEPREAF 22261
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 26/245 (10%)
Query: 298 EDGSMNCRCENNYFRADKDPPS--MACTR---PPSSPRNV-ISNINETSVILDWSWPLDT 351
++ S R N ++ PS + C PPS PR + + NI + + L W+ P
Sbjct: 7679 QEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKD 7738
Query: 352 GGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDA 411
GG +T N I +K K + V+ +T TVT L + Y F + A
Sbjct: 7739 GG-SPIT-NYIVEKRDVRRKGWQTVDTTVK---------DTKCTVTPLTEGSLYVFRVAA 7787
Query: 412 VNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYE 471
N + + + + ++ T P D T R+ + L W+ P++ G +
Sbjct: 7788 ENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQ-- 7844
Query: 472 VKYYEKQEQETSYTILRARGT-----NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+Y ++++ ++A T N ++ + T FQ+RA AG G S E
Sbjct: 7845 -RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEI 7903
Query: 527 ETSPD 531
+ D
Sbjct: 7904 LSIED 7908
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/212 (26%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNVRFLPRQFGL 389
+ ++ + V L W P + GGR + I K+ W +K + P+ F
Sbjct: 7820 VVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW-VKAGKTAGPDCNF------- 7871
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
VTD++ T F++ A N GV S P +SI + PSP L +
Sbjct: 7872 -----RVTDVIEGTEVQFQVRAENEAGVGHPSEPTE---ILSIEDPTSPPSPPLDLHVTD 7923
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKY----YEKQEQETSYTILRARGTNVTISSLKPD 502
R I+++W+ PE G I+ Y V+ EK + S I + + PD
Sbjct: 7924 AGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFK--VEEGVVPD 7981
Query: 503 TIYVFQIRARTAAGYGTNSRKFE--FETSPDC 532
YV ++RA A G S E PDC
Sbjct: 7982 KEYVLRVRAVNAIGVSEPSEISENVVAKDPDC 8013
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 28/218 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP P VIS + L W PL GG + + + ++ W + NV+
Sbjct: 16267 PPEGPV-VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA-----NVQ 16320
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSE-LSSPPRQFAAVSITTNQAAPS 438
L + VT LL YTF I AVN GV E L S P + +
Sbjct: 16321 TL---------SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16371
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG-TNVTI 496
V T+ KD S+ + W+ P G IL Y ++ +K+ + R G + +
Sbjct: 16372 EVTTVTKD-----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16426
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++ A AAG S ++ + D +Y
Sbjct: 16427 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16464
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 21/134 (15%)
Query: 299 DGSMNCRCENNYFRADKDPPSM---ACTR-----PPSSPRNVISNINETSVILDWSWPLD 350
D EN ++ PPS AC PP++P+ + +I +SV L WS P+
Sbjct: 16434 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPK--VIDITRSSVFLSWSKPIY 16491
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG + + I +KC ++ + C+P G+ T + V LL Y F I
Sbjct: 16492 DGGCEIQGY--IVEKCDVSVGEWTMCTPPT-------GINKTNIEVEKLLEKHEYNFRIC 16542
Query: 411 AVN--GVSELSSPP 422
A+N GV E + P
Sbjct: 16543 AINKAGVGEHADVP 16556
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 23/201 (11%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ ++NI + S+ + W+ P D+ G ++ I+ K+ I+ + C+
Sbjct: 17447 PGPPKSLEVTNIAKDSMTVCWNRP-DSDGGSEIIGYIVEKRDRSGIRWIK-CNKR----- 17499
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T+ + VT L Y F + A N GV E S + A P+
Sbjct: 17500 ---RITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17556
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE----TSYTILRARGTNVTIS 497
+ T++NSI+L+W +P + G IL Y V+ + E+E T T LR T IS
Sbjct: 17557 VD---TTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRV--TRFEIS 17611
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y ++ A G G
Sbjct: 17612 KLTEHQEYKIRVCALNKVGLG 17632
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 292 PHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLD 350
P+ ++D C N F D+ + P PR V +S+++ SV L W+ P
Sbjct: 24716 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPAS 24775
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG K N I +KC + R+L R T TV +L T+Y F +
Sbjct: 24776 DGGSK--ITNYIVEKCATTAE---------RWL-RVGQARETRYTVINLFGKTSYQFRVI 24823
Query: 411 AVN--GVSELSSP 421
A N G+S+ S P
Sbjct: 24824 AENKFGLSKPSEP 24836
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P PR++ +S I + S L W PLD GG V N + ++ Q P
Sbjct: 10938 PGPPRDLEVSEIRKDSCYLTWKEPLDDGG--SVITNYVVERRDVASAQWSP--------- 10986
Query: 385 RQFGLTNTTVTVTDLLAHTN----YTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L+ T+ + H N Y F + A N G P+ A+ P
Sbjct: 10987 ----LSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPK 11042
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV--T 495
+ + D+T +SL W +P+ G I Y V+Y QE+ T I TN+
Sbjct: 11043 DLHHVDVDKTE---VSLVWNKPDRDGGSPITGYLVEY---QEEGTQDWIKFKTVTNLECV 11096
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L+ Y F+++A G G
Sbjct: 11097 VTGLQQGKTYRFRVKAENIVGLG 11119
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 26/204 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P RN+ I +++ + W P D GG C+ + +++CE R +
Sbjct: 11925 PGPVRNLKIVDVSSDRCTVCWDPPEDDGG---------CEIQNYILEKCE----TKRMVW 11971
Query: 385 RQFGLTNTT--VTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T T TVT L+ Y F + A N + + PP + V T P
Sbjct: 11972 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG--TGPPTESKPVIAKTKYDKPGRPDP 12029
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGT----NVTIS 497
+ + S+ +++ W PE+ G I Y + EK+E+ ++ + + + +
Sbjct: 12030 PEVTKVSKEEMTVVWNPPEYDGGKSITGY---FLEKKEKHSTRWVPVNKSAIPERRMKVQ 12086
Query: 498 SLKPDTIYVFQIRARTAAGYGTNS 521
+L PD Y F+++A G G S
Sbjct: 12087 NLLPDHEYQFRVKAENEIGIGEPS 12110
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/209 (25%), Positives = 84/209 (40%), Gaps = 33/209 (15%)
Query: 326 PSSPRNVIS--NINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P+SP + +I SV + W P D GG + G+ +++ E P +
Sbjct: 23856 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL---------GYILERREV--PKAAWY 23904
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP---- 439
+ T++ V L + Y F + A N +S P + V+ T P P
Sbjct: 23905 TIDSRVRGTSLVVKGLKENVEYHFRVSAENQFG-ISKPLKSEEPVTPKTPLNPPEPPSNP 23963
Query: 440 --VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG----T 492
VL + K +S+SLSW P+ G + Y Y E++E T + + T
Sbjct: 23964 PEVLDVTK-----SSVSLSWSRPKDDGGSRVTGY---YIERKETSTDKWVRHNKTQITTT 24015
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNS 521
T++ L PD Y F+I A+ G S
Sbjct: 24016 MYTVTGLVPDAEYQFRIIAQNDVGLSETS 24044
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/201 (23%), Positives = 82/201 (40%), Gaps = 34/201 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
S+I ++S L W P GG + + + ++ G ++P G +
Sbjct: 8117 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRT-----------YIPVMSGENKLS 8165
Query: 394 VTVTDLLAHTNYTFEIDAVNGVS-----ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
TV DL+ + Y F + AVN V EL +P V + P P + ++
Sbjct: 8166 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP------VIAQDPKQPPDPPVDVEVHNP 8219
Query: 449 SRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVTISSLKP 501
+ +++++W+ P + G I+ Y ++ K E+ E IL T L+
Sbjct: 8220 TAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL-----TYTAKGLEE 8274
Query: 502 DTIYVFQIRARTAAGYGTNSR 522
Y F++RA AAG SR
Sbjct: 8275 GKEYQFRVRAENAAGISEPSR 8295
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/201 (22%), Positives = 80/201 (39%), Gaps = 25/201 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P NV + I++ S + W P+ GG + + + ++ W+ E CS
Sbjct: 13415 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CS---- 13469
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
T+ V +L +Y F + A N + P AV + P PV+
Sbjct: 13470 ---------KTSFRVANLEEGKSYFFRVFAENEYG-IGDPGETRDAVKASQT---PGPVV 13516
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+K S++S S+ W++P G I+ Y V + E+ ++++ + L
Sbjct: 13517 DLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLT 13574
Query: 501 PDTIYVFQIRARTAAGYGTNS 521
Y F++ A G GT S
Sbjct: 13575 EGKEYTFRVSAENENGEGTPS 13595
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + I++ S+++ W P++ GG + G+++++ E S +
Sbjct: 17053 PPGTP--FATAISKDSMVIQWHEPVNNGGSPVI---------GYHLERKERNSILWTKVN 17101
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T +L Y F + A N GV + S + A P P++
Sbjct: 17102 KTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMV 17160
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
RN I+L W +P + G ++ Y ++ ++A TNV T+S
Sbjct: 17161 ------KRNEITLQWTKPVYDGGSMI---TGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17211
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 17212 GLTEDQRYEFRVIAKNAAG 17230
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P+ + +I + SV L W P D GG +T ++ K+ S
Sbjct: 7116 PSAPKELKFGDITKDSVHLTWEPPDDDGG-SPLTGYVVEKR---------EVSRKTWTKV 7165
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
F +T+ TV DL+ Y F++ A N P V+++T P P +K
Sbjct: 7166 MDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGP-GEPAYVDEPVNMSTPATVPDPPENVK 7223
Query: 445 -KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+DRT+ NSI L+W P++ G I Y V+ + + T + ++ L+
Sbjct: 7224 WRDRTA-NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEG 7282
Query: 503 TIYVFQIRARTAAGYGTNSRKFE 525
Y ++++A G SR E
Sbjct: 7283 KWYAYRVKALNRQGASKPSRPTE 7305
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ +S+I S L W P D GG D + +K + K +P+
Sbjct: 9540 PGPPKDLKVSDITRGSCRLSWKMPDDDGG--DRIKGYVIEKRTIDGKAWTKVNPDCG--- 9594
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+TT V DLL+ Y F + A N + P + P P + +K
Sbjct: 9595 ------STTFVVPDLLSEQQYFFRVRAENRFG-IGPPVETIQRTTARDPIYPPDPPIKLK 9647
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYY------EKQEQETSYTILRARGTNVTIS 497
++N++ LSW+ P++ G + Y V+ K+E T+
Sbjct: 9648 IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9707
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+++A AAG
Sbjct: 9708 DLVEGGEYEFRVKAVNAAG 9726
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 32/201 (15%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP +P V++ + S+ + W+ P+ GG + + +++ K+ W +K + P +
Sbjct: 15971 PPGTP--VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTK 16027
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
F T L Y F + A N G+ + S + A P
Sbjct: 16028 F------------KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEA 16075
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVT 495
++ +RNS++L W++P + G I Y V+ E E + S+T T+
Sbjct: 16076 IIV------TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT--NIIDTHFE 16127
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
++ L D Y F++ AR AAG
Sbjct: 16128 VTGLVEDHRYEFRVIARNAAG 16148
Score = 43.9 bits (102), Expect = 4e-04
Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ S+ L W+ PL TGG + N I +K + S V
Sbjct: 16953 PPKGPVK-FDDVSAESITLSWNPPLYTGGCQ--ITNYIVQKRDTTTTVWDVVSATV---- 17005
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE---LSSPPRQFAAVSITTNQAAPSPVL 441
TT+ VT L T Y F I A N + L S P + P P
Sbjct: 17006 -----ARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP-----IVAQYPYKEPGPPG 17055
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTIS 497
T S++S+ + W EP + G ++ Y ++ E+ + + TI+ T
Sbjct: 17056 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII--HDTQFKAQ 17113
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+L+ Y F++ A G G S+ E + D
Sbjct: 17114 NLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17147
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/193 (23%), Positives = 76/193 (39%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+N+ + + + S L W P+ GG K + I ++ S +
Sbjct: 17744 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----------STRKAYAN 17792
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T+ V +L Y F + A N + P AV PSP +
Sbjct: 17793 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-VGVPVETVDAVKAAE---PPSPPGKVT 17848
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
S+ S SL W++PEH G +L Y V+ K ++ S + ++ N ++ L
Sbjct: 17849 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS-IVAESKVCNAVVTGLSSGQ 17907
Query: 504 IYVFQIRARTAAG 516
Y F+++A G
Sbjct: 17908 EYQFRVKAYNEKG 17920
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/206 (21%), Positives = 81/206 (39%), Gaps = 22/206 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ V++ W P TGG C+ + +++ + + +
Sbjct: 18035 PPVGPVR-FDEVSADFVVISWEPPAYTGG---------CQISNYIVEKRDTTTTTWHMVS 18084
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TT+ +T L T Y F I A N + S P AV + P P T
Sbjct: 18085 AT--VARTTIKITKLKTGTEYQFRIFAENRYGK--SAPLDSKAVIVQYPFKEPGPPGTPF 18140
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTI 504
S++ + + W EP + G + + Y+ +Q+++ S ++ T + + K +
Sbjct: 18141 VTSISKDQMLVQWHEPVNDGGTKI---IGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGL 18197
Query: 505 -----YVFQIRARTAAGYGTNSRKFE 525
Y F++ A G G S+ E
Sbjct: 18198 DEGLEYEFKVSAENIVGIGKPSKVSE 18223
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/235 (20%), Positives = 100/235 (42%), Gaps = 18/235 (7%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+++ED C +N + P ++ P P + I ++ S+ + W+ P GG
Sbjct: 19085 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGG 19144
Query: 354 RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
C+ + +++ E S + + + T++ + L + Y F + A N
Sbjct: 19145 ---------CQISNYIVEKKETTSTTWHIVSQ--AVARTSIKIVRLTTGSEYQFRVCAEN 19193
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEV 472
+ S + +AV + P P T K +++++ ++WQ P + G ++ Y +
Sbjct: 19194 RYGKSSYS--ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL 19251
Query: 473 KYYEKQE--QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+Y E+ + IL A T + +S L +Y +++ A AG G S+ E
Sbjct: 19252 EYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE 19305
Score = 43.9 bits (102), Expect = 4e-04
Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 317 PPSMACTRPPSSPRNVI--SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCE 374
P ++ PPS P+ I I SVIL W P D GG + I C ++I++ E
Sbjct: 21276 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE-----ITC----YSIEKRE 21326
Query: 375 PCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITT 432
N + + + TT V +L+ Y F + A N GVS+ P + +
Sbjct: 21327 TSQTNWKMVCS--SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ----PLVSSIIVAKH 21380
Query: 433 NQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILR 488
P P + + +SL+W P + G + + V+ E+ Q+ + + +
Sbjct: 21381 QFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 21440
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS--RKFEFETSP 530
R T L Y F++ A +AG + S KF SP
Sbjct: 21441 GREYRAT--GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21482
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 30/207 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P I I+ TS+ + W P GG G+ ++Q + P +LP
Sbjct: 23462 PPTGPIK-IDEIDATSITISWEPPELDGG---------APLSGYVVEQRDAHRPG--WLP 23509
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T +T T L Y F + A N G+ Q + ++ P P T
Sbjct: 23510 VSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSIRIPGPPET 23565
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE------QETSYTILRARGTNVT 495
++ SR+ ++L+W PE G + Y V+ E + + T+ R R T +T
Sbjct: 23566 LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLT 23625
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSR 522
Y ++ A A G G SR
Sbjct: 23626 -----EGLEYEHRVTAINARGSGKPSR 23647
Score = 43.1 bits (100), Expect = 6e-04
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P NV I+++N V L W P GG ++T +I + +I+ + L
Sbjct: 6819 PGPPLNVTITDVNRFGVSLTWEPPEYDGGA-EITNYVIELRDKTSIRWDTAMTVRAEDL- 6876
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TVTD++ Y+F + A N + + P V + PSP + +
Sbjct: 6877 --------SATVTDVVEGQEYSFRVRAQNRIG-VGKPSAATPFVKVADPIERPSPPVNLT 6927
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEK-QEQETSYTILRARGTNVTISSLKPD 502
+++S+ L W+ P G IL Y ++ E+ ++ + ++ L+
Sbjct: 6928 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 6987
Query: 503 TIYVFQIRARTAAG 516
Y++++ A AG
Sbjct: 6988 NKYLYRVSAENKAG 7001
Score = 43.1 bits (100), Expect = 6e-04
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 17/97 (17%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNI-ICKKC--GWNIKQCEPCSPNV 380
PP P V +++ ++T+V L+WS P+ GG + + + I +CK W+ E C
Sbjct: 21881 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC---- 21936
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE 417
T TVTDL A Y F + A+NG +
Sbjct: 21937 ---------VKTRYTVTDLQAGEEYKFRVSAINGAGK 21964
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + + +++ W PLD GG K + I K+ G ++ ++P
Sbjct: 10542 PPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDV-----------WMP 10589
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT V+ LL +Y F I A N G+S+ A A P++T
Sbjct: 10590 VTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVT 10649
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W +P I +Y EK+E + R VT + P
Sbjct: 10650 ----EVTKDSALVTWNKPHDGGKPITNY---ILEKRE------TMSKRWARVTKDPIHPY 10696
Query: 503 T-----------IYVFQIRARTAAGYGTNS 521
T Y F++ A G G S
Sbjct: 10697 TKFRVPDLLEGCQYEFRVSAENEIGIGDPS 10726
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 30/204 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNII----CKKCGWNIKQCEPCSPNVRFLPRQFG 388
+S + + L WS P + GG ++T I+ + W I + E P + ++
Sbjct: 22777 VSRVTQEKCTLAWSLPQEDGG-AEITHYIVERRETSRLNWVIVEGE--CPTLSYV----- 22828
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
VT L+ + Y F + AVN P + + + PSP ++ T
Sbjct: 22829 -------VTRLIKNNEYIFRVRAVNKYG--PGVPVESEPIVARNSFTIPSPPGIPEEVGT 22879
Query: 449 SRNSISLSWQEPEHPNG-IILDYEVKYYEKQ-----EQETSYTILRARGTNVTISSLKPD 502
+ I + W +PE G I +Y V EK+ Y + T + ++SL
Sbjct: 22880 GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVY---DTRLKVTSLMEG 22936
Query: 503 TIYVFQIRARTAAGYGTNSRKFEF 526
Y F++ A AAG S F
Sbjct: 22937 CDYQFRVTAVNAAGNSEPSEASNF 22960
Score = 40.4 bits (93), Expect = 0.004
Identities = 47/205 (22%), Positives = 82/205 (40%), Gaps = 34/205 (16%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNV 380
PPS+P R + +++ ++ + W P GG K + + + K+ W + PC
Sbjct: 22468 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC---- 22523
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
VT L+ Y F A+N GVS+ S R A + P
Sbjct: 22524 ---------LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE 22574
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARG 491
+R+++SL W P + G ++ Y ++ E + +YTI+
Sbjct: 22575 VT------DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS--D 22626
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T+++L Y F++ A+ AAG
Sbjct: 22627 NFFTVTALSEGDTYEFRVLAKNAAG 22651
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 16/189 (8%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
SNI S+ L W+ P GG + + + ++ + + V+ + ++ ++ T
Sbjct: 21789 SNITGNSITLTWARPESDGGSEIQQYILERRE--------KKSTRWVKVISKR-PISETR 21839
Query: 394 VTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
VT L Y F + A N GV S R + P P +K TS+
Sbjct: 21840 FKVTGLTEGNEYEFHVMAENAAGVGPASGISR---LIKCREPVNPPGPPTVVKVTDTSKT 21896
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTISSLKPDTIYVFQI 509
++SL W +P G+ I+ Y ++ + + A T T++ L+ Y F++
Sbjct: 21897 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 21956
Query: 510 RARTAAGYG 518
A AG G
Sbjct: 21957 SAINGAGKG 21965
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 28/204 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P+ + + S+++ W+ PLD GG +T G+ +++ E SP +
Sbjct: 9229 PPGKPKVLART--KGSMLVSWTPPLDNGG-SPIT--------GYWLEKREEGSPYWSRVS 9277
Query: 385 R----QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS-- 438
R + GL V LL Y F A+N PP + + + + P
Sbjct: 9278 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG--IGPPSEPSDPEVAGDPIFPPGP 9335
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT-- 495
P KD+T ++SISL W+ P G I Y V+ E E T + + +T
Sbjct: 9336 PSCPEVKDKT-KSSISLGWKPPAKDGGSPIKGYIVEMQE--EGTTDWKRVNEPDKLITTC 9392
Query: 496 ---ISSLKPDTIYVFQIRARTAAG 516
+ +LK Y F+++A AG
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAG 9416
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/197 (23%), Positives = 85/197 (43%), Gaps = 25/197 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP-RQFGLTN 391
++ +++ + + W+ P GG K +T G+ +++ E S R++P + +
Sbjct: 12032 VTKVSKEEMTVVWNPPEYDGG-KSIT--------GYFLEKKEKHS--TRWVPVNKSAIPE 12080
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
+ V +LL Y F + A N G+ E S P R A P P + T+
Sbjct: 12081 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE---PPGPPTNFRVVDTT 12137
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEK---QEQETSYTILRARGTNV----TISSLKP 501
++SI+L W +P + G I+ Y V+ K + + A V T++SL
Sbjct: 12138 KHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDE 12197
Query: 502 DTIYVFQIRARTAAGYG 518
+ Y F++ A+ G G
Sbjct: 12198 NQEYEFRVCAQNQVGIG 12214
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + ++ ++ L W+ PL GG K V ++I E N R++
Sbjct: 21485 PPGTPDYI--DVTRETITLKWNPPLRDGGSKIVGYSI------------EKRQGNERWVR 21530
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
F ++ TVT L Y F I A N V + SPP Q + + +T ++ P
Sbjct: 21531 CNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI-SPPSQSSGIIMTRDENVP 21583
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P V NI +V L W+ P TGG K +T I+ K+ PN R+L
Sbjct: 14987 PPGKP--VPLNITRHTVTLKWAKPEYTGGFK-ITSYIVEKRD----------LPNGRWLK 15033
Query: 385 RQFG-LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + TV+ L Y F + A N +S P A++ + AP + +
Sbjct: 15034 ANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDV 15093
Query: 444 K 444
K
Sbjct: 15094 K 15094
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 329 PRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
PRNV I++I++ SV L W P GG K +T I+ ++ P+ R+ F
Sbjct: 20399 PRNVRITDISKNSVSLSWQQPAFDGGSK-ITGYIVERRD----------LPDGRWTKASF 20447
Query: 388 -GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
+T T ++ L ++ Y F + A N V +S+P ++ + P
Sbjct: 20448 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP 20498
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 27/194 (13%)
Query: 332 VISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTN 391
VI + + S ++ W P D GG N + +KC + ++
Sbjct: 24359 VIEALLKNSAVISWKPPADDGG--SWITNYVVEKC--------EAKEGAEWQLVSSAISV 24408
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQ-----AAPSPVLTIK 444
TT + +L + Y F + A N G+S+ P + ++V I + A P +T
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISD----PLEVSSVVIIKSPFEKPGAPGKPTIT-- 24462
Query: 445 KDRTSRNSISLSWQEPEHPNGIILD--YEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W+ P G + Y K +KQ + S T R T ++ +L
Sbjct: 24463 --AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEG 24520
Query: 503 TIYVFQIRARTAAG 516
Y F+++ G
Sbjct: 24521 LEYEFRVKCENLGG 24534
Score = 38.1 bits (87), Expect = 0.021
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P +P ++ + + S+I+ W P GG + + + ++ K+ I+ R R
Sbjct: 16368 PKAPE--VTTVTKDSMIVVWERPASDGGSEILGY-VLEKRDKEGIRW-------TRCHKR 16417
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
G + VT L+ + +Y F + A N G+SE SPP + + P P
Sbjct: 16418 LIG--ELRLRVTGLIENHDYEFRVSAENAAGLSE-PSPPSAYQKACDPIYK--PGPPNNP 16472
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILR----ARGTNVTI 496
K +R+S+ LSW +P + G E++ Y ++ + S +T+ TN+ +
Sbjct: 16473 KVIDITRSSVFLSWSKPIYDGGC----EIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEV 16528
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNS 521
L Y F+I A AG G ++
Sbjct: 16529 EKLLEKHEYNFRICAINKAGVGEHA 16553
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++NI SV L WS P GG K G+ +++ E P+ R+L
Sbjct: 19315 PPGQPE--VTNITRKSVSLKWSKPHYDGGAKIT---------GYIVERRE--LPDGRWLK 19361
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + T VT+L Y F + A N +S P + + + P ++ +
Sbjct: 19362 CNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDV 19421
Query: 444 K 444
K
Sbjct: 19422 K 19422
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PPS P + V+++I E + + W+ P GG +T G+ +++ E VR
Sbjct: 11331 PPSPPGKPVVTDITENAATVSWTLPKSDGG-SPIT--------GYYMERREVTGKWVRV- 11380
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + VT L Y F + A N ++ LS P + P P +
Sbjct: 11381 -NKTPIADLKFRVTGLYEGNTYEFRVFAEN-LAGLSKPSPSSDPIKACRPIKPPGPPINP 11438
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVK 473
K SR + L W +P G IL Y V+
Sbjct: 11439 KLKDKSRETADLVWTKPLSDGGSPILGYVVE 11469
Score = 37.7 bits (86), Expect = 0.027
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T+T + + + + + + + A N V E+ ++I + P IK D S
Sbjct: 14747 TSTILNINECVRSDSGPYPLTARNIVGEVGD------VITIQVHDIPGPPTGPIKFDEVS 14800
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+ ++ SW PE+ G+ I +Y V+ +Q T++ L T + + T +Q
Sbjct: 14801 SDFVTFSWDPPENDGGVPISNYVVEM--RQTDSTTWVELATTVIRTTYKATRLTTGLEYQ 14858
Query: 509 IRARTAAGYG 518
R + YG
Sbjct: 14859 FRVKAQNRYG 14868
Score = 37.4 bits (85), Expect = 0.035
Identities = 40/200 (20%), Positives = 75/200 (37%), Gaps = 25/200 (12%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNV 380
RP ++N+ + + + W PLD GG + F + +K GW+I + +
Sbjct: 11629 RPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI 11688
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ +LLA+ Y F + A N GV A++ P
Sbjct: 11689 K---------------ANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPE 11733
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTI 496
+ K +T + L W+ P++ G L Y V+ K + + + T+ +
Sbjct: 11734 NLHIADKGKT---FVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMV 11790
Query: 497 SSLKPDTIYVFQIRARTAAG 516
+ IY F+++ + G
Sbjct: 11791 DRCVENQIYEFRVQTKNEGG 11810
Score = 37.4 bits (85), Expect = 0.035
Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 395 TVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T L+ Y F + AVN GV A + T A P + + NS
Sbjct: 21740 TAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP----EPSNITGNS 21795
Query: 453 ISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSLKPDTIYVFQI 509
I+L+W PE G I Y ++ EK+ I + T ++ L Y F +
Sbjct: 21796 ITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21855
Query: 510 RARTAAGYGTNS 521
A AAG G S
Sbjct: 21856 MAENAAGVGPAS 21867
Score = 37.0 bits (84), Expect = 0.046
Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I +V L W P GG K +T I+ KK P+ R++
Sbjct: 18233 PPGRPEAIV--ITRNNVTLKWKKPAYDGGSK-ITGYIVEKKD----------LPDGRWMK 18279
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + T TV+ L+ Y F + A N S P A++ AP+ L
Sbjct: 18280 ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDP 18339
Query: 444 K 444
K
Sbjct: 18340 K 18340
Score = 37.0 bits (84), Expect = 0.046
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T T++++ + T+E+ N ++ P + + P P I+ D S
Sbjct: 19076 TVTSLSIKEASKEDVGTYELCVSNSAGSITVP----ITIIVLDRPGPPGP---IRIDEVS 19128
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+SI++SW PE+ G I +Y V+ +K+ T++ I+ +I ++ T +Q
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVE--KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQ 19186
Query: 509 IRARTAAGYGTNS 521
R YG +S
Sbjct: 19187 FRVCAENRYGKSS 19199
Score = 37.0 bits (84), Expect = 0.046
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 20/201 (9%)
Query: 324 RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRF 382
R P P + I +++ + L W P D GG + VT I+ +K ++ N
Sbjct: 23558 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ-VTGYIVERK---EVRADRWVRVN--- 23610
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAP-SP 439
+ +T T T L Y + A+N G + S P + A+ P +P
Sbjct: 23611 ---KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 23667
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE-TSYTILRARGTNVTIS 497
+T T+R S+SL+W PE G + Y ++ + + E T + T++
Sbjct: 23668 RVT----DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLT 23723
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y F++ A A G G
Sbjct: 23724 HLPQGAEYRFRVLACNAGGPG 23744
Score = 36.6 bits (83), Expect = 0.060
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + NI SV L W+ P GG K +T I+ K+ P+ ++
Sbjct: 13904 PPGKPE--VINITRNSVTLIWTEPKYDGGHK-LTGYIVEKRD----------LPSKSWMK 13950
Query: 385 -RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL-- 441
+ TVTDL+ Y F I A N +S+P + AP+ VL
Sbjct: 13951 ANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDP 14010
Query: 442 TIKKDRT 448
TIK T
Sbjct: 14011 TIKDGLT 14017
Score = 36.2 bits (82), Expect = 0.078
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PV +K ++ S +SW PE+ G + Y V+ E + S + T+
Sbjct: 12327 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12386
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+++L P Y F++ A G G
Sbjct: 12387 VTNLVPGNEYYFRVTAVNEYGPG 12409
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/214 (21%), Positives = 78/214 (36%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P + + S+ L W P GG N I +K + + S V
Sbjct: 15871 PPTGPVKM-DEVTADSITLSWGPPKYDGGSS--INNYIVEKRDTSTTTWQIVSATV---- 15923
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT+ L Y F I A N G S + A +PV+T
Sbjct: 15924 -----ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15978
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ +SR+S+ + W EP G + Y+ ++++ S ++ T + + K
Sbjct: 15979 L----SSRDSMEVQWNEPISDGG---SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTT 16031
Query: 503 TI-----YVFQIRARTAAGYGTNSRKFEFETSPD 531
+ Y F++ A G G S+ E + D
Sbjct: 16032 GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 16065
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/89 (26%), Positives = 37/89 (41%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTI 496
P P +K SR+S++L+W EP G + + E + +AR T T+
Sbjct: 24750 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTV 24809
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+L T Y F++ A G S E
Sbjct: 24810 INLFGKTSYQFRVIAENKFGLSKPSEPSE 24838
Score = 35.0 bits (79), Expect = 0.17
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ + T++ L+W P GG + V + + + G N + C+ +
Sbjct: 8630 PPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN--EWSRCTEKM-IKV 8686
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
RQ+ TV ++ +Y + AVN E PP + V++ Q P+ L +
Sbjct: 8687 RQY-------TVKEIREGADYKLRVSAVNAAGE--GPPGETQPVTVAEPQEPPAVELDV 8736
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 21/167 (12%)
Query: 305 RCENNYFRADK-DPPSMACTRP---PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
R EN + ++ P M P PS P+N ++ +N+ + + W P GG + +
Sbjct: 12695 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12754
Query: 360 NIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGV-SEL 418
+I +K ++ + VR +T L+ Y+F I A+N S
Sbjct: 12755 -LIERKERNSLLWVKANDTLVR---------STEYPCAGLVEGLEYSFRIYALNKAGSSP 12804
Query: 419 SSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
S P ++ + + V+ + K +++SL W P+H G
Sbjct: 12805 PSKPTEYVTARMPVDPPGKPEVIDVTK-----STVSLIWARPKHDGG 12846
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 25/200 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +I + SV L W P GG K +T I+ KK P R++
Sbjct: 16069 PPGRPEAII--VTRNSVTLQWKKPTYDGGSK-ITGYIVEKKE----------LPEGRWMK 16115
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + +T VT L+ Y F + A N S P A++ P I
Sbjct: 16116 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPP----RI 16171
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYE--KQEQETSYTI-LRARGTNVTISSLK 500
D +++I + E + I + + K +QE S T L + T+ S
Sbjct: 16172 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16231
Query: 501 PDTIYV----FQIRARTAAG 516
D + V + ++A+ AG
Sbjct: 16232 KDAVRVDSGNYILKAKNVAG 16251
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ V + ++++++ W P++ GG + + +++ K+ S +
Sbjct: 19217 PPGTPKVV--HATKSTMLVTWQVPVNDGGSRVIGYHLEYKER----------SSILWSKA 19264
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T + V+ L Y + + A N G+ + S A P
Sbjct: 19265 NKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVT-- 19322
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R S+SL W +P + G I Y V+ E + + +YT ++ T ++
Sbjct: 19323 ----NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE--TYFEVTE 19376
Query: 499 LKPDTIYVFQIRARTAA 515
L D Y F++ AR AA
Sbjct: 19377 LTEDQRYEFRVFARNAA 19393
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 14/127 (11%)
Query: 317 PPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
P + T P+ PR + + + +++S +L W P GG + + + ++ G +
Sbjct: 22165 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSD------ 22218
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
F T TV L+ T Y F + A N S P F++V I Q
Sbjct: 22219 ------FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAG-YSEPREAFSSVIIKEPQI 22271
Query: 436 APSPVLT 442
P+ LT
Sbjct: 22272 EPTADLT 22278
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P IK +++S L+W+ PE G IL Y ++ E + + + T
Sbjct: 8108 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8167
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+ L P+ Y F+++A G G
Sbjct: 8168 VKDLIPNGEYFFRVKAVNKVGGG 8190
Score = 34.3 bits (77), Expect = 0.30
Identities = 39/183 (21%), Positives = 70/183 (38%), Gaps = 18/183 (9%)
Query: 337 NETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTV 396
N +L+WS P D GG ++T II +K +P + +
Sbjct: 8837 NRKMCLLNWSDPEDDGG-SEITGFIIERKDAKMHTWRQPIETE-----------RSKCDI 8884
Query: 397 TDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLS 456
T LL Y F + A N PP + + P+ + ++++I+L
Sbjct: 8885 TGLLEGQEYKFRVIAKNKFG--CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8942
Query: 457 WQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRART 513
W+EP G + E + ++K + E L T+ + +L +Y F+++A
Sbjct: 8943 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYEFRVKAVN 9001
Query: 514 AAG 516
G
Sbjct: 9002 EIG 9004
Score = 34.3 bits (77), Expect = 0.30
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P ++K SR+S++++W+ P G + +Y V+ E + + T
Sbjct: 23166 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23225
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
IS L T+Y F++ G G
Sbjct: 23226 ISGLVEGTMYYFRVLPENIYGIG 23248
Score = 33.9 bits (76), Expect = 0.39
Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T + + + D L + + I A N +FAA + P PVL +K T+
Sbjct: 8785 TKSELIIKDALRKDHGRYVITATNSCGS------KFAAARVEVFDV-PGPVLDLKPVVTN 8837
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
R L+W +PE G + + + + T + + I+ L Y F++
Sbjct: 8838 RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRV 8897
Query: 510 RARTAAGYG 518
A+ G G
Sbjct: 8898 IAKNKFGCG 8906
Score = 33.9 bits (76), Expect = 0.39
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
++N R R K +M PP P+N +++ TSV L WS P D GG K +
Sbjct: 23636 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23695
Query: 360 NIICKK 365
I +K
Sbjct: 23696 LIEMQK 23701
Score = 33.5 bits (75), Expect = 0.51
Identities = 39/194 (20%), Positives = 79/194 (40%), Gaps = 17/194 (8%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P + ++ SV + W P GG N I +K ++ + +
Sbjct: 23166 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAP--VNNYIVEKREAAMRAFKTVTTKC---- 23219
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T ++ L+ T Y F + N + + P AV ++ P+ + +
Sbjct: 23220 -----SKTLYRISGLVEGTMYYFRVLPEN-IYGIGEPCETSDAVLVSEVPLVPAKLEVVD 23273
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV--TISSLKPD 502
++++++L+W++P + G L V K E ++ + T + T++SL
Sbjct: 23274 ---VTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEG 23330
Query: 503 TIYVFQIRARTAAG 516
Y+F+IRA+ G
Sbjct: 23331 EQYLFRIRAQNEKG 23344
Score = 33.1 bits (74), Expect = 0.66
Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PP+SP R + ++++ LDW P GG G+ I++ P+ +
Sbjct: 8922 PPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQ---------GYIIEKRRHDKPDFERV 8972
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
++ T T+ V +L H Y F + AVN + E S P V I ++ P TI
Sbjct: 8973 NKRLCPT-TSFLVENLDEHQMYEFRVKAVNEIGE--SEPSLPLNVVIQDDEVPP----TI 9025
Query: 444 KKDRTSR-NSISLSWQEPEHPNGIILDYEVKYYEKQEQET 482
K + R ++I + EP H + + E + ET
Sbjct: 9026 KLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNET 9065
Score = 32.7 bits (73), Expect = 0.86
Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 7/129 (5%)
Query: 391 NTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
++ +T+ + L ++I N + AV +T P I +
Sbjct: 11193 SSVLTIKNCLRRDTGEYQITVSNAAGSKT------VAVHLTVLDVPGPPTGPINILDVTP 11246
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+++SWQ P+ G +++Y V+ + ++ + T + I L+ YVF++
Sbjct: 11247 EHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11306
Query: 510 RARTAAGYG 518
RA G G
Sbjct: 11307 RAENKIGVG 11315
Score = 32.7 bits (73), Expect = 0.86
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PVL ++ +++S++L W P G I +Y V+ E + S +
Sbjct: 14496 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14555
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L Y F++ A G G
Sbjct: 14556 VTGLSEGCEYFFRVMAENEYGIG 14578
Score = 32.7 bits (73), Expect = 0.86
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 8/138 (5%)
Query: 392 TTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
TT T L Y F + A N P A + P P T + +++
Sbjct: 14844 TTYKATRLTTGLEYQFRVKAQNRYGV--GPGITSACIVANYPFKVPGPPGTPQVTAVTKD 14901
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISSLKPDTIYVF 507
S+++SW EP G IL Y V+ E+ Q S ++ G S L Y F
Sbjct: 14902 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV--PGNIFKSSGLTDGIAYEF 14959
Query: 508 QIRARTAAGYGTNSRKFE 525
++ A AG S+ E
Sbjct: 14960 RVIAENMAGKSKPSKPSE 14977
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 37/151 (24%)
Query: 318 PSMACT--RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WN-- 369
P AC +PP P N + + + + L W+ PL GG + + + C+K G WN
Sbjct: 11422 PIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRI 11481
Query: 370 -----IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ 424
I+QC V L+ Y F I A N V E PR+
Sbjct: 11482 NKDELIRQC-------------------AFRVPGLIEGNEYRFRIKAANIVGE--GEPRE 11520
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
A I + P V + D T R+ I++
Sbjct: 11521 LAESVIAKDILHPPEV---ELDVTCRDVITV 11548
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 9/99 (9%)
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSY 484
F A + P PV +K S + ++ W PE G E++ Y ++ ET
Sbjct: 11913 FVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGC----EIQNYILEKCETKR 11968
Query: 485 TILRARGTNV-----TISSLKPDTIYVFQIRARTAAGYG 518
+ V T++ L Y+F++RA G G
Sbjct: 11969 MVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 12007
Score = 31.6 bits (70), Expect = 1.9
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P ++ NE + L W+ P+ GG +T I+ K+ P+ R++
Sbjct: 17151 PPGTPEPIMVKRNE--ITLQWTKPVYDGGSM-ITGYIVEKRD----------LPDGRWMK 17197
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
F + T TV+ L Y F + A N +S P
Sbjct: 17198 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKP 17235
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 437 PSPVLT-IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
P PV T + S L+W PE G I +Y ++ E + +YT+ R
Sbjct: 10244 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ-- 10301
Query: 492 TNVTISSLKPDTIYVFQIRARTAAGYG 518
N T+ L Y F+I A + G G
Sbjct: 10302 -NATVQGLIQGKAYFFRIAAENSIGMG 10327
Score = 30.4 bits (67), Expect = 4.3
Identities = 23/99 (23%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P +K +R S LSW+ P+ G I Y ++ + + T
Sbjct: 9540 PGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFV 9599
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++RA G G + T+ D +Y
Sbjct: 9600 VPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9638
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 426 AAVSITTNQAAPSPV-LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETS 483
A V++ + +PV LTI++ ++S++LSW+ P G I +Y V+ E + +
Sbjct: 18817 AFVNVRVLDSPSAPVNLTIRE--VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18874
Query: 484 YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
T I +L+ Y F++ A G G
Sbjct: 18875 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 18909
Score = 29.6 bits (65), Expect = 7.3
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILRARGT 492
+P P + R ++ +L+W P+ G E+ +Y + +ETS + I+
Sbjct: 22768 SPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA----EITHYIVERRETSRLNWVIVEGECP 22823
Query: 493 NVT--ISSLKPDTIYVFQIRARTAAGYG 518
++ ++ L + Y+F++RA G G
Sbjct: 22824 TLSYVVTRLIKNNEYIFRVRAVNKYGPG 22851
Score = 29.6 bits (65), Expect = 7.3
Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 9/128 (7%)
Query: 393 TVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T+ T + YT E+ V G + + + P IK D S
Sbjct: 23425 TIRETTIRDTGEYTLELKNVTGTTS--------ETIKVIILDKPGPPTGPIKIDEIDATS 23476
Query: 453 ISLSWQEPEHPNGIILD-YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
I++SW+ PE G L Y V+ + + + L YVF++ A
Sbjct: 23477 ITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAA 23536
Query: 512 RTAAGYGT 519
G G+
Sbjct: 23537 TNRFGIGS 23544
Score = 29.6 bits (65), Expect = 7.3
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
+P + + I+ + + S ++ W P GG K + + ++ N K + +R
Sbjct: 24452 KPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQN-KWISVTTEEIR-- 24508
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVL 441
T +V +L+ Y F + N G SE S + IT P
Sbjct: 24509 -------ETVFSVKNLIEGLEYEFRVKCENLGGESEWSE-----ISEPITPKSDVPIQAP 24556
Query: 442 TIKKDRTSRN-----SISLSWQEPEHPNGIILDYEVKYYEKQEQETS----YTILRARGT 492
K++ + N + +L + HP I VK+Y + ++ + Y I +G
Sbjct: 24557 HFKEELRNLNVRYQSNATLVCKVTGHPKPI-----VKWYRQGKEIIADGLKYRIQEFKGG 24611
Query: 493 --NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFE 527
+ I+S+ D V+Q+RA G + + E E
Sbjct: 24612 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24648
Score = 29.3 bits (64), Expect = 9.5
Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 20/158 (12%)
Query: 286 KCAKCPPHSSTQEDGS---MNCRCENNYFRADKDPPS--MACTRPPSSPRNV-ISNINET 339
KC KC + +G EN Y + + + + PS P ++ I +I ++
Sbjct: 14548 KCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKS 14607
Query: 340 SVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDL 399
+V L W P GG K + I ++ G S + GL V +L
Sbjct: 14608 TVSLAWPKPKHDGGSKITGYVIEAQRKG---------SDQWTHITTVKGL---ECVVRNL 14655
Query: 400 LAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
YTF++ AVN S PR+ V + P
Sbjct: 14656 TEGEEYTFQVMAVNSAGR--SAPRESRPVIVKEQTMLP 14691
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 63.2 bits (152), Expect = 6e-10
Identities = 58/199 (29%), Positives = 91/199 (45%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PPS+P +S I + S+++ W+ P+D GG ++ I+ K+ ++ + C+
Sbjct: 18407 PPSTPE--VSAITKDSMVVTWARPVDDGGT-EIEGYILEKRDKEGVRWTK-CNKKT---- 18458
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ + VT L +Y F + A N GV E S P + A P P
Sbjct: 18459 ----LTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALY---PPGPPSN 18511
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
K TSR+S+SL+W +P + G + EVK E T +G T++ L
Sbjct: 18512 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKL 18571
Query: 500 KPDTIYVFQIRARTAAGYG 518
K +T Y F+I A + G G
Sbjct: 18572 KENTEYNFRICAINSEGVG 18590
Score = 61.6 bits (148), Expect = 2e-09
Identities = 58/205 (28%), Positives = 93/205 (45%), Gaps = 30/205 (14%)
Query: 324 RPPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSP 378
R P +P + +++ + + S ++ W+ P D G K +T I+ K+ W +P P
Sbjct: 10513 RVPDAPDQPIVTEVTKDSALVTWNKPHDGG--KPITNYILEKRETMSKRWARVTKDPIHP 10570
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQ-FAAVSITTNQA 435
+F V DLL Y F + A N G+ + S P + FA I A
Sbjct: 10571 YTKF------------RVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPI----A 10614
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
PSP + + T+ NS+ L+WQ P H G IL Y V+Y + ++E ++T
Sbjct: 10615 KPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPE 10674
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T ++ L+ Y F++ A AAG
Sbjct: 10675 TKYKVTGLRDGQTYKFRVLAVNAAG 10699
Score = 60.8 bits (146), Expect = 3e-09
Identities = 51/199 (25%), Positives = 89/199 (44%), Gaps = 20/199 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I + S+ + WS P+ GG D++ + K+ ++ + +R
Sbjct: 20571 PPGIPE--VTKITKNSMTVVWSRPIADGG-SDISGYFLEKRDKKSLGWFKVLKETIR--- 20624
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T VT L +++Y + + AVN G S P + A P P
Sbjct: 20625 ------DTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPID---PPGPPAK 20675
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSL 499
I+ ++++SI+L W +P + G + E++ E++E T T R T +S+L
Sbjct: 20676 IRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNL 20735
Query: 500 KPDTIYVFQIRARTAAGYG 518
KP Y F++ A AG G
Sbjct: 20736 KPGVNYYFRVSAVNCAGQG 20754
Score = 59.3 bits (142), Expect = 9e-09
Identities = 66/205 (32%), Positives = 94/205 (45%), Gaps = 36/205 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PPS+P V+ ++ ++SV L WS P D GG + VT G+ I++ E + VR
Sbjct: 23834 PPSNPPEVL-DVTKSSVSLSWSRPKDDGGSR-VT--------GYYIERKETSTDKWVRHN 23883
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELS--SPPRQFAAVSITTNQAAPSP 439
Q +T T TVT L+ Y F I A N G+SE S S P +Q
Sbjct: 23884 KTQ--ITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKY-------YEKQEQETSYTILRARG 491
+L+I KD S++L W++PE G IL Y V+Y ++K +E R +
Sbjct: 23942 ILSISKD-----SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKE------RIKD 23990
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
TI L T Y F++ A G
Sbjct: 23991 KQFTIGGLLEATEYEFRVFAENETG 24015
Score = 58.5 bits (140), Expect = 1e-08
Identities = 51/202 (25%), Positives = 84/202 (41%), Gaps = 20/202 (9%)
Query: 316 DPPSMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
DPP PP P + ++ +TSV L+W+ P GG K ++ I K G +
Sbjct: 7485 DPPW-----PPGKP--TVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTD------ 7531
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
++ G+ T + L+ Y+F + AVN E S P V
Sbjct: 7532 -----EWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGE-SEPSEPSDPVLCREKLY 7585
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV 494
PSP ++ ++N+ L W PE G I +Y V+ + + + + T
Sbjct: 7586 PPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKC 7645
Query: 495 TISSLKPDTIYVFQIRARTAAG 516
T++ L ++YVF++ A A G
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIG 7667
Score = 58.2 bits (139), Expect = 2e-08
Identities = 63/243 (25%), Positives = 107/243 (44%), Gaps = 28/243 (11%)
Query: 298 EDGSMNCRCENNYFRADKDPPSMACTRPPSSPRN-VISNINETSVILDWSWPLDTGGRKD 356
+ G + EN++ A K P +++ P P N V +I +TSV+ W PLD GG +
Sbjct: 8278 DHGLYMIKVENDHGIA-KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEI 8336
Query: 357 VTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVS 416
+ + +++ + P+ ++ L + +VT L+ Y F + A N
Sbjct: 8337 INY---------TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAEN--- 8384
Query: 417 ELSSPPRQFAAVSITTNQAAP--SPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKY 474
P + + + P +P I +D TS NS+ + W EP+ IL Y +
Sbjct: 8385 RFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTS-NSMLVKWNEPKDNGSPILGY---W 8440
Query: 475 YEKQEQETSY------TILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFET 528
EK+E +++ ++L A NV L YVF++ A AAG G S + +T
Sbjct: 8441 LEKREVNSTHWSRVNKSLLNALKANV--DGLLEGLTYVFRVCAENAAGPGKFSPPSDPKT 8498
Query: 529 SPD 531
+ D
Sbjct: 8499 AHD 8501
Score = 56.2 bits (134), Expect = 7e-08
Identities = 60/223 (26%), Positives = 88/223 (39%), Gaps = 19/223 (8%)
Query: 307 ENNYFRADKDPPSMACTRPPSSPRN-----VISNINETSVILDWSWPLDTGGRKDVTFNI 361
EN Y D A + P P VISNI + + + W P D GG +T
Sbjct: 12968 ENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGG-SPIT--- 13023
Query: 362 ICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
G+ +++ E + N + R+ + T+ T L T Y F + A+N P
Sbjct: 13024 -----GYLLEKRETQAVNWTKVNRK-PIIERTLKATGLQEGTEYEFRVTAINKAGP-GKP 13076
Query: 422 PRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDY--EVKYYEKQ 478
A Q P P K T+R+S+SLSW +P + G I+ Y EVK +
Sbjct: 13077 SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSD 13136
Query: 479 EQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS 521
+ T ++ L DT Y F++ A GY S
Sbjct: 13137 NWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPS 13179
Score = 55.8 bits (133), Expect = 1e-07
Identities = 48/190 (25%), Positives = 89/190 (46%), Gaps = 22/190 (11%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S++ +TS + W+ P + GG + VT I+ K+ + K +P V+ T
Sbjct: 12210 VSDVTKTSCHVSWAPPENDGGSQ-VTHYIVEKREA-DRKTWSTVTPEVK---------KT 12258
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT+L+ Y F + AVN G + P+ A + + P P ++ ++
Sbjct: 12259 SFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLA---SDPLSEPDPPRKLEVTEMTK 12315
Query: 451 NSISLSWQEPEHPNGIILDYEVKYYEKQEQE----TSYTILRARGTNVTISSLKPDTIYV 506
NS +L+W P G +D + Y ++EQ T Y+++ + ++ ++ LK Y
Sbjct: 12316 NSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVV--KDLSLVVTGLKEGKKYK 12373
Query: 507 FQIRARTAAG 516
F++ AR A G
Sbjct: 12374 FRVAARNAVG 12383
Score = 55.8 bits (133), Expect = 1e-07
Identities = 58/222 (26%), Positives = 91/222 (40%), Gaps = 42/222 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L WS PL GG D++ ++ K+ W + E
Sbjct: 17224 PPEGPVQV-TGVTSEKCSLTWSPPLQDGG-SDISHYVVEKRETSRLAWTVVASE------ 17275
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ ++ VT LL Y F I AVN GV E P + A V + P
Sbjct: 17276 --------VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE----PLESAPVLMKNPFVLPG 17323
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTN 493
P +++ +++S+++ W P+ G I+ Y V EK+++ I R
Sbjct: 17324 PPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIV---EKRDRSGIRWIKCNKRRITDLR 17380
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMYY 535
+ ++ L D Y F++ A AAG G E SP +YY
Sbjct: 17381 LRVTGLTEDHEYEFRVSAENAAGVG--------EPSPATVYY 17414
Score = 55.8 bits (133), Expect = 1e-07
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 15/201 (7%)
Query: 319 SMACTRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSP 378
S PP P V + +I+ W+ P GG +++ ++ K+ E S
Sbjct: 22739 SFTIPSPPGIPEEV--GTGKEHIIIQWTKPESDGGN-EISNYLVDKR--------EKKSL 22787
Query: 379 NVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS 438
+ + + + +T + VT L+ +Y F + AVN S P +S P
Sbjct: 22788 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN-SEPSEASNFISCREPSYTPG 22846
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE--TSYTILRARGTNVT 495
P + T+++SISL+W +P + G I+ Y ++ EK + +T R T T
Sbjct: 22847 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 22906
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
+ LK Y F++ A G
Sbjct: 22907 VPDLKMGQKYSFRVAAVNVKG 22927
Score = 55.5 bits (132), Expect = 1e-07
Identities = 58/237 (24%), Positives = 97/237 (40%), Gaps = 29/237 (12%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTR-------PPSSPRNVISNINETSVILDWSW 347
+T E+ + EN + +D + + PPS+P ++N+ S+ + W
Sbjct: 20138 TTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPW--VTNVTRESITVGWHE 20195
Query: 348 PLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTF 407
P+ GG V +++ K + Q + + T VT + A Y F
Sbjct: 20196 PVSNGGSAVVGYHLEMKDRNSILWQ----------KANKLVIRTTHFKVTTISAGLIYEF 20245
Query: 408 EIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
+ A N GV + S P A+ A P ++ S+NS+SLSWQ+P G
Sbjct: 20246 RVYAENAAGVGKPSHPSEPVLAID------ACEPPRNVRITDISKNSVSLSWQQPAFDGG 20299
Query: 466 I-ILDYEVKYYEKQE-QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTN 520
I Y V+ + + + T + T IS L ++ Y F++ AR A G +N
Sbjct: 20300 SKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISN 20356
Score = 55.1 bits (131), Expect = 2e-07
Identities = 57/207 (27%), Positives = 88/207 (42%), Gaps = 24/207 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P VIS+I E SV L W P GG + VT I+ K+ E + R
Sbjct: 20075 PPTGPV-VISDITEESVTLKWEPPKYDGGSQ-VTNYILLKRETSTAVWTEVSATVAR--- 20129
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
T + V L Y F I A N G+S+ A V++ P P T
Sbjct: 20130 -------TMMKVMKLTTGEEYQFRIKAENRFGISDHIDS----ACVTVKLPYTTPGPPST 20178
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R SI++ W EP G ++ Y ++ ++ Q+ + ++R T+ +++
Sbjct: 20179 PWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRT--THFKVTT 20236
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFE 525
+ IY F++ A AAG G S E
Sbjct: 20237 ISAGLIYEFRVYAENAAGVGKPSHPSE 20263
Score = 52.8 bits (125), Expect = 8e-07
Identities = 50/196 (25%), Positives = 82/196 (41%), Gaps = 24/196 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P N+ + ++ + S +L W P + GG ++I K W + C+
Sbjct: 19781 PGPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAW-VSVTNNCN---- 19835
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
+ VT+L Y F + N + P V IT PSP
Sbjct: 19836 ---------RLSYKVTNLQEGAIYYFRVSGENEFG-VGIPAETKEGVKITEK---PSPPE 19882
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+ S++S+SL+W +PEH G I+ Y V+ EK Q+ A+ T+ +S L+
Sbjct: 19883 KLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEK-GQKNWVKCAVAKSTHHVVSGLR 19941
Query: 501 PDTIYVFQIRARTAAG 516
++ Y F++ A AG
Sbjct: 19942 ENSEYFFRVFAENQAG 19957
Score = 52.0 bits (123), Expect = 1e-06
Identities = 52/193 (26%), Positives = 80/193 (41%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ + + +TSV L W PL GG K N I +K K + N
Sbjct: 15455 PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSK--IKNYIVEKRESTRKAYSTVATNCH--- 15509
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T+ V L +Y F + A N + P +V + P + +
Sbjct: 15510 ------KTSWKVDQLQEGCSYYFRVLAENEYG-IGLPAETAESVKASERPLPPGKITLMD 15562
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RNS+SLSW++PEH G IL Y V+ K + + T + T TI+ L
Sbjct: 15563 ---VTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA-TCATVKVTEATITGLIQGE 15618
Query: 504 IYVFQIRARTAAG 516
Y F++ A+ G
Sbjct: 15619 EYSFRVSAQNEKG 15631
Score = 51.6 bits (122), Expect = 2e-06
Identities = 54/197 (27%), Positives = 81/197 (41%), Gaps = 26/197 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS P N+ ++ I + SV + W PL GG K N I +K K N
Sbjct: 16537 PSPPVNLKVTEITKDSVSITWEPPLLDGGSK--IKNYIVEKREATRKSYAAVVTNCH--- 16591
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN----GVSELSSPPRQFAAVSITTNQAAPSPV 440
+ + L +Y F + A N G+ ++ P + A V P P
Sbjct: 16592 ------KNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEV--------PQPP 16637
Query: 441 LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSL 499
I D +RNS+SLSW +PEH G I+ Y V+ K ++ S R + I++L
Sbjct: 16638 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWS-ECARVKSLQAVITNL 16696
Query: 500 KPDTIYVFQIRARTAAG 516
Y+F++ A G
Sbjct: 16697 TQGEEYLFRVVAVNEKG 16713
Score = 51.2 bits (121), Expect = 2e-06
Identities = 54/202 (26%), Positives = 93/202 (46%), Gaps = 26/202 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PP P +SN+ + + + W P+D GG ++T G+++++ E S VR +
Sbjct: 14077 PPEKPE--VSNVTKNTATVSWKRPVDDGG-SEIT--------GYHVERREKKSLRWVRAI 14125
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAA--PSPVL 441
+ +++ VT L + Y F + A N PP + A+ S+ AA P P
Sbjct: 14126 --KTPVSDLRCKVTGLQEGSTYEFRVSAENRAG--IGPPSE-ASDSVLMKDAAYPPGPPS 14180
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ----ETSYTILRARGTNVTI 496
T++ S SL+W +P + G+ I Y V++ + ++ +T+ T LR T +
Sbjct: 14181 NPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRI--TQFVV 14238
Query: 497 SSLKPDTIYVFQIRARTAAGYG 518
L+ Y F+I A AG G
Sbjct: 14239 PDLQTKEKYNFRISAINDAGVG 14260
Score = 50.8 bits (120), Expect = 3e-06
Identities = 49/195 (25%), Positives = 76/195 (38%), Gaps = 21/195 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P VI N+ + L W P+ GG + F++ K+ + Q SP
Sbjct: 21262 PPGKP--VIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSP------ 21313
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
++ T L+ +Y F + A N G+S S P + AVS P +
Sbjct: 21314 ----ISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYI-- 21367
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKP 501
+R +I+L W P G I+ Y ++ + E+ T++ L P
Sbjct: 21368 ----DVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSP 21423
Query: 502 DTIYVFQIRARTAAG 516
Y F+I AR A G
Sbjct: 21424 GDRYEFRIIARNAVG 21438
Score = 50.4 bits (119), Expect = 4e-06
Identities = 52/193 (26%), Positives = 79/193 (40%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P N+ I + + SV L W PL GG K N I +K K + N
Sbjct: 18702 PSAPVNLTIREVKKDSVTLSWEPPLIDGGAKIT--NYIVEKRETTRKAYATITNNC---- 18755
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
T TT + +L +Y F + A N + P V ++ P V +
Sbjct: 18756 -----TKTTFRIENLQEGCSYYFRVLASNEYG-IGLPAETTEPVKVSEPPLPPGRVTLVD 18809
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
+RN+ ++ W++PE G I Y V+ K ++ S T + + TIS L
Sbjct: 18810 ---VTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWS-TCTQVKTLEATISGLTAGE 18865
Query: 504 IYVFQIRARTAAG 516
YVF++ A G
Sbjct: 18866 EYVFRVAAVNEKG 18878
Score = 50.1 bits (118), Expect = 5e-06
Identities = 54/217 (24%), Positives = 85/217 (39%), Gaps = 39/217 (17%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP+ P I+ + L W P + GG D+ + I+ K+ W I + E
Sbjct: 19388 PPAGPLE-INGLTAEKCSLSWGRPQEDGGA-DIDYYIVEKRETSHLAWTICEGE------ 19439
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L T+ VT LL Y F + VN GV E P + A+ PS
Sbjct: 19440 --------LQMTSCKVTKLLKGNEYIFRVTGVNKYGVGE----PLESVAIKALDPFTVPS 19487
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRAR-----GTN 493
P +++ ++ S++L W PE G + Y ++ ++ S +R
Sbjct: 19488 PPTSLEITSVTKESMTLCWSRPESDGGSEIS---GYIIERREKNSLRWVRVNKKPVYDLR 19544
Query: 494 VTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSP 530
V + L+ Y +++ A AAG S ETSP
Sbjct: 19545 VKSTGLREGCEYEYRVYAENAAGLSLPS-----ETSP 19576
Score = 49.3 bits (116), Expect = 9e-06
Identities = 47/191 (24%), Positives = 80/191 (41%), Gaps = 25/191 (13%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
+S+++ S +L W P D GG + + + ++ G Q S + T
Sbjct: 22253 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSS-----------VKRT 22301
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
+ VT L + Y+F + + N GVS+ P + A + PS + S
Sbjct: 22302 QIKVTHLTKYMEYSFRVSSENRFGVSK----PLESAPIIAEHPFVPPSAPTRPEVYHVSA 22357
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRAR----GTNVTISSLKPDTIY 505
N++S+ W+EP H G I+ Y + EK+E+ T + + N ++ L Y
Sbjct: 22358 NAMSIRWEEPYHDGGSKIIGY---WVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEY 22414
Query: 506 VFQIRARTAAG 516
F+ A AAG
Sbjct: 22415 QFRTYALNAAG 22425
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/201 (24%), Positives = 84/201 (41%), Gaps = 20/201 (9%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL- 383
P + + +S++ S+ ++W P GG VT G+ ++ + S + +
Sbjct: 9820 PGAPDKPTVSSVTRNSMTVNWEEPEYDGG-SPVT--------GYWLEMKDTTSKRWKRVN 9870
Query: 384 --PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
P + + VT L+ ++Y F + A+N GV S P A P P
Sbjct: 9871 RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFP 9930
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSY-TILRARGTNVTIS 497
+T +++S L W P G + Y V+Y E+ ++E RGT + ++
Sbjct: 9931 KVT----DWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVT 9986
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
LK Y F++RA AG G
Sbjct: 9987 GLKEGAFYKFRVRAVNIAGIG 10007
Score = 48.5 bits (114), Expect = 2e-05
Identities = 51/212 (24%), Positives = 93/212 (43%), Gaps = 26/212 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + IS+I+ + L W PL+ GG ++T N I +KC ++ + + ++
Sbjct: 12497 PPQPPFD-ISDIDADACSLSWHIPLEDGG-SNIT-NYIVEKC--DVSRGD-------WVT 12544
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T T+ V L+ Y F + A N G+SE + P+ A PS
Sbjct: 12545 ALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPF----GVPSEPKN 12600
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRA-----RGTNVTIS 497
+ + +++ I ++W P+ G + + Y ++++ S ++A R T +
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPI---IGYLIERKERNSLLWVKANDTLVRSTEYPCA 12657
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETS 529
L Y F+I A AG S+ E+ T+
Sbjct: 12658 GLVEGLEYSFRIYALNKAGSSPPSKPTEYVTA 12689
Score = 48.5 bits (114), Expect = 2e-05
Identities = 50/199 (25%), Positives = 82/199 (41%), Gaps = 17/199 (8%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICK-KCGWNIKQCEPCSPNVRF 382
PP P+N ++ I + S+++ W P GG + + + + + K G +C +
Sbjct: 15157 PPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKT----- 15211
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
LT+ V+ L Y F I A N +S+P P P
Sbjct: 15212 ------LTDLRYKVSGLTEGHEYEFRIMAENAAG-ISAPSPTSPFYKACDTVFKPGPPGN 15264
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSL 499
+ TSR+SIS++W +P + G I Y V+ +E E A + T+ TI+ L
Sbjct: 15265 PRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGL 15324
Query: 500 KPDTIYVFQIRARTAAGYG 518
+ Y +I A + G G
Sbjct: 15325 TENQEYKIRIYAMNSEGLG 15343
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/210 (23%), Positives = 83/210 (39%), Gaps = 26/210 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIK--QCEPCSPN 379
P RN+ ++ + V L W PL GG K + + + K+ W + + E C
Sbjct: 6593 PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFT 6652
Query: 380 VRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP 439
V L + Y F + A N V P V + P P
Sbjct: 6653 VTGLQK---------------GGVEYLFRVSARNRVGT-GEPVETDNPVEARSKYDVPGP 6696
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQ--EQETSYTILRARGTNVTI 496
L + +R +SL+W+ PE+ G I +Y ++ +K +T+ T+ RA + T+
Sbjct: 6697 PLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTV-RAEDLSATV 6755
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+ + Y F++RA+ G G S F
Sbjct: 6756 TDVVEGQEYSFRVRAQNRIGVGKPSAATPF 6785
Score = 48.1 bits (113), Expect = 2e-05
Identities = 61/261 (23%), Positives = 95/261 (36%), Gaps = 38/261 (14%)
Query: 287 CAKCPPHSSTQEDGSMNCRCENNYFRADKDPPSMACTRP--PSSPRNVISNINETSVILD 344
C P S + G NN A K+ RP P P +++ + L
Sbjct: 9682 CTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIK-FESVSADQMTLS 9740
Query: 345 WSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLA 401
W P D GG K + I ++ W EP T T+ LL
Sbjct: 9741 WFPPKDDGGSKITNYVIEKREANRKTWVHVSSEP--------------KECTYTIPKLLE 9786
Query: 402 HTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQE 459
Y F I A N G+ E + A + A P ++ +RNS++++W+E
Sbjct: 9787 GHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVS----SVTRNSMTVNWEE 9842
Query: 460 PEHPNGIILDYEVKYYEKQEQETSYTILRAR---------GTNVTISSLKPDTIYVFQIR 510
PE+ G + Y+ + + TS R G + ++ L + Y F++
Sbjct: 9843 PEYDGGSPV---TGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVY 9899
Query: 511 ARTAAGYGTNSRKFEFETSPD 531
A AAG G S + T+ D
Sbjct: 9900 AINAAGVGPASLPSDPATARD 9920
Score = 48.1 bits (113), Expect = 2e-05
Identities = 48/199 (24%), Positives = 89/199 (44%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P +++I++ +++ W P++ GG K + G++++Q E S L
Sbjct: 18010 PPGTP--FVTSISKDQMLVQWHEPVNDGGTKII---------GYHLEQKEKNSILWVKLN 18058
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T T L Y F++ A N G+ + S F A P ++
Sbjct: 18059 KT-PIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVI 18117
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RN+++L W++P + G + Y +++ ++A TNV T+S
Sbjct: 18118 ------TRNNVTLKWKKPAYDGGSKI---TGYIVEKKDLPDGRWMKASFTNVLETEFTVS 18168
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ AR AAG
Sbjct: 18169 GLVEDQRYEFRVIARNAAG 18187
Score = 48.1 bits (113), Expect = 2e-05
Identities = 50/194 (25%), Positives = 83/194 (42%), Gaps = 15/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPN-VRFL 383
PS P ++ I+++ + S+ L WS P GG + G+ I++ E S VR
Sbjct: 19486 PSPPTSLEITSVTKESMTLCWSRPESDGGSEI---------SGYIIERREKNSLRWVRVN 19536
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + V T L Y + + A N LS P + PSP
Sbjct: 19537 KKP--VYDLRVKSTGLREGCEYEYRVYAENAAG-LSLPSETSPLIRAEDPVFLPSPPSKP 19593
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
K + + +I+++W +P G I Y V+Y + + + +I RGT TIS L
Sbjct: 19594 KIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTG 19653
Query: 503 TIYVFQIRARTAAG 516
YVF++++ G
Sbjct: 19654 AEYVFRVKSVNKVG 19667
Score = 47.8 bits (112), Expect = 3e-05
Identities = 56/222 (25%), Positives = 95/222 (42%), Gaps = 29/222 (13%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS PRN+ +++I S L W PLD GG ++T +I K+ + K+ E +
Sbjct: 9001 PSPPRNLAVTDIKAESCYLTWDAPLDNGG-SEITHYVIDKRDA-SRKKAEWEEVTNTAVE 9058
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+++G + L+ + Y F + AVN G+S+ + V I P P
Sbjct: 9059 KRYG-------IWKLIPNGQYEFRVRAVNKYGISDECKSDK----VVIQDPYRLPGPPGK 9107
Query: 443 IKKDRTSRNSISLSWQEP-EHPNGIILDYEVKYYEKQEQETSY---------TILRARGT 492
K ++ S+ +SW P ++ I Y + EK+E+ + Y T + +G
Sbjct: 9108 PKVLARTKGSMLVSWTPPLDNGGSPITGY---WLEKREEGSPYWSRVSRAPITKVGLKGV 9164
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L Y F+ A AAG G S + E + D ++
Sbjct: 9165 EFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIF 9206
Score = 47.8 bits (112), Expect = 3e-05
Identities = 53/254 (20%), Positives = 92/254 (36%), Gaps = 38/254 (14%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+T++D N F + + P P V ISN++ L W+ PL+ GG
Sbjct: 13945 ATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPVEISNVSAEKATLTWTPPLEDGG 14004
Query: 354 --------RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNY 405
K T ++ +I+ C T L+ Y
Sbjct: 14005 SPIKSYILEKRETSRLLWTVVSEDIQSCRH-------------------VATKLIQGNEY 14045
Query: 406 TFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
F + AVN + P Q V + P P + ++N+ ++SW+ P G
Sbjct: 14046 IFRVSAVNHYGK--GEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGG 14103
Query: 466 IILDYEVKYYEKQEQETSYTILRARGTNVT-----ISSLKPDTIYVFQIRARTAAGYGTN 520
+ Y+ ++ ++ S +RA T V+ ++ L+ + Y F++ A AG G
Sbjct: 14104 SEI---TGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPP 14160
Query: 521 SRKFEFETSPDCMY 534
S + D Y
Sbjct: 14161 SEASDSVLMKDAAY 14174
Score = 47.8 bits (112), Expect = 3e-05
Identities = 44/198 (22%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICK---KCGWNIKQCEPCSPNVR 381
P + + + +++ +V L W PL GG + + I + K W++ CS
Sbjct: 20869 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVS-HKCS---- 20923
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
+T+ + DL T + F + A N G+ E A + P+P
Sbjct: 20924 ---------STSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEV------PAP 20968
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGTNVTISS 498
+ + +++ S+ LSW +P+ G +I +Y V+ K EQ S+ + ++ + +S
Sbjct: 20969 IRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGI-SKTCEIEVSQ 21027
Query: 499 LKPDTIYVFQIRARTAAG 516
LK ++ F++ A+ G
Sbjct: 21028 LKEQSVLEFRVFAKNEKG 21045
Score = 47.0 bits (110), Expect = 4e-05
Identities = 52/199 (26%), Positives = 83/199 (41%), Gaps = 26/199 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P + P I ++ SV L W+ P TGG +++ K+ + + +P +R
Sbjct: 13679 PDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTP-IRM-- 13735
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
R F VT L Y F + A+N GV + S P A+ P +
Sbjct: 13736 RDF-------KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVI-- 13786
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+RNS++L W EP++ G L Y ++ S + ++A NV T++
Sbjct: 13787 ----NITRNSVTLIWTEPKYDGGHKL---TGYIVEKRDLPSKSWMKANHVNVPECAFTVT 13839
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+IRA+ AG
Sbjct: 13840 DLVEGGKYEFRIRAKNTAG 13858
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/200 (22%), Positives = 84/200 (42%), Gaps = 25/200 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNT 392
I+++ S +L W+ P D GG K N + ++ + + S V+ +T
Sbjct: 7295 ITDVTNESCLLTWNPPRDDGGSK--ITNYVVERRATDSEVWHKLSSTVK---------DT 7343
Query: 393 TVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
T L+ + Y F + A N GV E P Q + ++ P P ++ ++
Sbjct: 7344 NFKATKLIPNKEYIFRVAAENMYGVGE----PVQASPITAKYQFDPPGPPTRLEPSDITK 7399
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTI----LRARGTNVTISSLKPDTIY 505
++++L+W EP+ G I Y + E+ + +T + + + T + L Y
Sbjct: 7400 DAVTLTWCEPDDDGGSPITGY---WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKY 7456
Query: 506 VFQIRARTAAGYGTNSRKFE 525
F++ A AG G S+ E
Sbjct: 7457 RFRVLAENLAGPGKPSKSTE 7476
Score = 46.6 bits (109), Expect = 6e-05
Identities = 45/199 (22%), Positives = 85/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ ++ + + S+ + W PL GG + +++ K+ + Q + +
Sbjct: 14764 PPGTPQ--VTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14821
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ GLT+ Y F + A N G S+ S P A+ P P+
Sbjct: 14822 KSSGLTDGIA----------YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL-- 14869
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
+R++++L W +PE+ G + Y ++ + L+A +N+ T+S
Sbjct: 14870 ----NITRHTVTLKWAKPEYTGGFKI---TSYIVEKRDLPNGRWLKANFSNILENEFTVS 14922
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 14923 GLTEDAAYEFRVIAKNAAG 14941
Score = 46.6 bits (109), Expect = 6e-05
Identities = 57/225 (25%), Positives = 87/225 (38%), Gaps = 42/225 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK----CGWNIKQCEPCSPNV 380
PP P V + + L W+ PL GG +++ II K+ W E + N
Sbjct: 18307 PPEGPLKV-TGVTAEKCYLAWNPPLQDGGA-NISHYIIEKRETSRLSWTQVSTEVQALNY 18364
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ VT LL Y F + AVN G+ E P + V+ P
Sbjct: 18365 K--------------VTKLLPGNEYIFRVMAVNKYGIGE----PLESGPVTACNPYKPPG 18406
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQE---------TSYTILRA 489
P T + +++S+ ++W P G + E EK+++E + T LR
Sbjct: 18407 PPSTPEVSAITKDSMVVTWARPVDDGGT--EIEGYILEKRDKEGVRWTKCNKKTLTDLRL 18464
Query: 490 RGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
R T +T Y F++ A AAG G S F + D +Y
Sbjct: 18465 RVTGLTEGHS-----YEFRVAAENAAGVGEPSEPSVFYRACDALY 18504
Score = 46.2 bits (108), Expect = 8e-05
Identities = 45/191 (23%), Positives = 75/191 (39%), Gaps = 31/191 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNI-----ICKKCGWNIKQCEPCSPNVRFLPRQFG 388
++I + SV L W PL GG + + + K +C C
Sbjct: 14380 TDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC------------ 14427
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKD 446
T VT L Y F + A N G+ E + A APSP ++
Sbjct: 14428 ----TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKA------SEAPSPPDSLNIM 14477
Query: 447 RTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIY 505
+++++SL+W +P+H G I Y ++ K + ++ I +G + +L Y
Sbjct: 14478 DITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQWTH-ITTVKGLECVVRNLTEGEEY 14536
Query: 506 VFQIRARTAAG 516
FQ+ A +AG
Sbjct: 14537 TFQVMAVNSAG 14547
Score = 46.2 bits (108), Expect = 8e-05
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 30/219 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ + +L W PLD GG K + I+ K+ + S
Sbjct: 15060 PPEGPL-AVTEVTSEKCVLSWFPPLDDGGAK-IDHYIVQKRETSRLAWTNVASE------ 15111
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T + VT LL Y F + AVN GV E P + V P P
Sbjct: 15112 ----VQVTKLKVTKLLKGNEYIFRVMAVNKYGVGE----PLESEPVLAVNPYGPPDPPKN 15163
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVT 495
+ +++S+ + W P+ G I++Y V+ +K Q + + T LR +
Sbjct: 15164 PEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYK----- 15218
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+S L Y F+I A AAG S F + D ++
Sbjct: 15219 VSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVF 15257
Score = 45.8 bits (107), Expect = 1e-04
Identities = 50/213 (23%), Positives = 88/213 (41%), Gaps = 24/213 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + L W P D GG K +T I+ K+ + V +
Sbjct: 20471 PPGGPIE-FKTVTAEKITLLWRPPADDGGAK-ITHYIVEKRE----------TSRVVWSM 20518
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
L +T T ++ Y F + AVN G+ E P + +V P P
Sbjct: 20519 VSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE----PLESDSVVAKNAFVTPGPPGI 20574
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS--YTILR--ARGTNVTISS 498
+ + ++NS+++ W P G D + EK+++++ + +L+ R T ++
Sbjct: 20575 PEVTKITKNSMTVVWSRPIADGG--SDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTG 20632
Query: 499 LKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
L ++ Y +++ A AAG G S EF + D
Sbjct: 20633 LTENSDYQYRVCAVNAAGQGPFSEPSEFYKAAD 20665
Score = 45.8 bits (107), Expect = 1e-04
Identities = 41/141 (29%), Positives = 60/141 (42%), Gaps = 16/141 (11%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
T V DL Y F + AVN GV E P + + T Q AP L +
Sbjct: 22006 TRQIFKVNDLAEGVPYYFRVSAVNEYGVGE----PYEMPEPIVATEQPAPPRRLDVVD-- 22059
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ---ETSYTILRARGTNVTISSLKPDT 503
TS++S L+W +P+H G I Y ++ +K E +T + T+ L T
Sbjct: 22060 TSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEAGHT----KQLTFTVERLVEKT 22115
Query: 504 IYVFQIRARTAAGYGTNSRKF 524
Y F+++A+ AGY F
Sbjct: 22116 EYEFRVKAKNDAGYSEPREAF 22136
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/245 (23%), Positives = 98/245 (40%), Gaps = 26/245 (10%)
Query: 298 EDGSMNCRCENNYFRADKDPPS--MACTR---PPSSPRNV-ISNINETSVILDWSWPLDT 351
++ S R N ++ PS + C PPS PR + + NI + + L W+ P
Sbjct: 7554 QEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKD 7613
Query: 352 GGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDA 411
GG +T N I +K K + V+ +T TVT L + Y F + A
Sbjct: 7614 GG-SPIT-NYIVEKRDVRRKGWQTVDTTVK---------DTKCTVTPLTEGSLYVFRVAA 7662
Query: 412 VNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYE 471
N + + + + ++ T P D T R+ + L W+ P++ G +
Sbjct: 7663 ENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRH-VDLKWEPPKNDGGRPIQ-- 7719
Query: 472 VKYYEKQEQETSYTILRARGT-----NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEF 526
+Y ++++ ++A T N ++ + T FQ+RA AG G S E
Sbjct: 7720 -RYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEI 7778
Query: 527 ETSPD 531
+ D
Sbjct: 7779 LSIED 7783
Score = 45.4 bits (106), Expect = 1e-04
Identities = 56/212 (26%), Positives = 84/212 (39%), Gaps = 30/212 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNVRFLPRQFGL 389
+ ++ + V L W P + GGR + I K+ W +K + P+ F
Sbjct: 7695 VVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRW-VKAGKTAGPDCNF------- 7746
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDR 447
VTD++ T F++ A N GV S P +SI + PSP L +
Sbjct: 7747 -----RVTDVIEGTEVQFQVRAENEAGVGHPSEPTE---ILSIEDPTSPPSPPLDLHVTD 7798
Query: 448 TSRNSISLSWQEPEHPNGI-ILDYEVKY----YEKQEQETSYTILRARGTNVTISSLKPD 502
R I+++W+ PE G I+ Y V+ EK + S I + + PD
Sbjct: 7799 AGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFK--VEEGVVPD 7856
Query: 503 TIYVFQIRARTAAGYGTNSRKFE--FETSPDC 532
YV ++RA A G S E PDC
Sbjct: 7857 KEYVLRVRAVNAIGVSEPSEISENVVAKDPDC 7888
Score = 45.4 bits (106), Expect = 1e-04
Identities = 57/218 (26%), Positives = 87/218 (39%), Gaps = 28/218 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP P VIS + L W PL GG + + + ++ W + NV+
Sbjct: 16142 PPEGPV-VISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDA-----NVQ 16195
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSE-LSSPPRQFAAVSITTNQAAPS 438
L + VT LL YTF I AVN GV E L S P + +
Sbjct: 16196 TL---------SCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16246
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG-TNVTI 496
V T+ KD S+ + W+ P G IL Y ++ +K+ + R G + +
Sbjct: 16247 EVTTVTKD-----SMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRV 16301
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++ A AAG S ++ + D +Y
Sbjct: 16302 TGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIY 16339
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/134 (29%), Positives = 59/134 (44%), Gaps = 21/134 (15%)
Query: 299 DGSMNCRCENNYFRADKDPPSM---ACTR-----PPSSPRNVISNINETSVILDWSWPLD 350
D EN ++ PPS AC PP++P+ + +I +SV L WS P+
Sbjct: 16309 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPK--VIDITRSSVFLSWSKPIY 16366
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG + + I +KC ++ + C+P G+ T + V LL Y F I
Sbjct: 16367 DGGCEIQGY--IVEKCDVSVGEWTMCTPPT-------GINKTNIEVEKLLEKHEYNFRIC 16417
Query: 411 AVN--GVSELSSPP 422
A+N GV E + P
Sbjct: 16418 AINKAGVGEHADVP 16431
Score = 45.4 bits (106), Expect = 1e-04
Identities = 53/201 (26%), Positives = 88/201 (43%), Gaps = 23/201 (11%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ ++NI + S+ + W+ P D+ G ++ I+ K+ I+ + C+
Sbjct: 17322 PGPPKSLEVTNIAKDSMTVCWNRP-DSDGGSEIIGYIVEKRDRSGIRWIK-CNKR----- 17374
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T+ + VT L Y F + A N GV E S + A P+
Sbjct: 17375 ---RITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17431
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE----TSYTILRARGTNVTIS 497
+ T++NSI+L+W +P + G IL Y V+ + E+E T T LR T IS
Sbjct: 17432 VD---TTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRV--TRFEIS 17486
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y ++ A G G
Sbjct: 17487 KLTEHQEYKIRVCALNKVGLG 17507
Score = 45.4 bits (106), Expect = 1e-04
Identities = 39/133 (29%), Positives = 57/133 (42%), Gaps = 15/133 (11%)
Query: 292 PHSSTQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLD 350
P+ ++D C N F D+ + P PR V +S+++ SV L W+ P
Sbjct: 24591 PNGVERKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPAS 24650
Query: 351 TGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEID 410
GG K N I +KC + R+L R T TV +L T+Y F +
Sbjct: 24651 DGGSK--ITNYIVEKCATTAE---------RWL-RVGQARETRYTVINLFGKTSYQFRVI 24698
Query: 411 AVN--GVSELSSP 421
A N G+S+ S P
Sbjct: 24699 AENKFGLSKPSEP 24711
Score = 45.1 bits (105), Expect = 2e-04
Identities = 52/203 (25%), Positives = 80/203 (39%), Gaps = 31/203 (15%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P PR++ +S I + S L W PLD GG V N + ++ Q P
Sbjct: 10813 PGPPRDLEVSEIRKDSCYLTWKEPLDDGG--SVITNYVVERRDVASAQWSP--------- 10861
Query: 385 RQFGLTNTTVTVTDLLAHTN----YTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
L+ T+ + H N Y F + A N G P+ A+ P
Sbjct: 10862 ----LSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPK 10917
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNV--T 495
+ + D+T +SL W +P+ G I Y V+Y QE+ T I TN+
Sbjct: 10918 DLHHVDVDKTE---VSLVWNKPDRDGGSPITGYLVEY---QEEGTQDWIKFKTVTNLECV 10971
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L+ Y F+++A G G
Sbjct: 10972 VTGLQQGKTYRFRVKAENIVGLG 10994
Score = 45.1 bits (105), Expect = 2e-04
Identities = 47/204 (23%), Positives = 84/204 (41%), Gaps = 26/204 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P RN+ I +++ + W P D GG C+ + +++CE R +
Sbjct: 11800 PGPVRNLKIVDVSSDRCTVCWDPPEDDGG---------CEIQNYILEKCE----TKRMVW 11846
Query: 385 RQFGLTNTT--VTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ T T TVT L+ Y F + A N + + PP + V T P
Sbjct: 11847 STYSATVLTPGTTVTRLIEGNEYIFRVRAENKIG--TGPPTESKPVIAKTKYDKPGRPDP 11904
Query: 443 IKKDRTSRNSISLSWQEPEHPNG-IILDYEVKYYEKQEQETSYTILRARGT----NVTIS 497
+ + S+ +++ W PE+ G I Y + EK+E+ ++ + + + +
Sbjct: 11905 PEVTKVSKEEMTVVWNPPEYDGGKSITGY---FLEKKEKHSTRWVPVNKSAIPERRMKVQ 11961
Query: 498 SLKPDTIYVFQIRARTAAGYGTNS 521
+L PD Y F+++A G G S
Sbjct: 11962 NLLPDHEYQFRVKAENEIGIGEPS 11985
Score = 45.1 bits (105), Expect = 2e-04
Identities = 53/209 (25%), Positives = 84/209 (40%), Gaps = 33/209 (15%)
Query: 326 PSSPRNVIS--NINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
P+SP + +I SV + W P D GG + G+ +++ E P +
Sbjct: 23731 PNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL---------GYILERREV--PKAAWY 23779
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSP---- 439
+ T++ V L + Y F + A N +S P + V+ T P P
Sbjct: 23780 TIDSRVRGTSLVVKGLKENVEYHFRVSAENQFG-ISKPLKSEEPVTPKTPLNPPEPPSNP 23838
Query: 440 --VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARG----T 492
VL + K +S+SLSW P+ G + Y Y E++E T + + T
Sbjct: 23839 PEVLDVTK-----SSVSLSWSRPKDDGGSRVTGY---YIERKETSTDKWVRHNKTQITTT 23890
Query: 493 NVTISSLKPDTIYVFQIRARTAAGYGTNS 521
T++ L PD Y F+I A+ G S
Sbjct: 23891 MYTVTGLVPDAEYQFRIIAQNDVGLSETS 23919
Score = 44.7 bits (104), Expect = 2e-04
Identities = 48/201 (23%), Positives = 82/201 (40%), Gaps = 34/201 (16%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
S+I ++S L W P GG + + + ++ G ++P G +
Sbjct: 7992 SDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRT-----------YIPVMSGENKLS 8040
Query: 394 VTVTDLLAHTNYTFEIDAVNGVS-----ELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
TV DL+ + Y F + AVN V EL +P V + P P + ++
Sbjct: 8041 WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNP------VIAQDPKQPPDPPVDVEVHNP 8094
Query: 449 SRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARGTNVTISSLKP 501
+ +++++W+ P + G I+ Y ++ K E+ E IL T L+
Sbjct: 8095 TAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL-----TYTAKGLEE 8149
Query: 502 DTIYVFQIRARTAAGYGTNSR 522
Y F++RA AAG SR
Sbjct: 8150 GKEYQFRVRAENAAGISEPSR 8170
Score = 44.7 bits (104), Expect = 2e-04
Identities = 46/201 (22%), Positives = 80/201 (39%), Gaps = 25/201 (12%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNII---CKKCGWNIKQCEPCSPNVR 381
P P NV + I++ S + W P+ GG + + + ++ W+ E CS
Sbjct: 13290 PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CS---- 13344
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL 441
T+ V +L +Y F + A N + P AV + P PV+
Sbjct: 13345 ---------KTSFRVANLEEGKSYFFRVFAENEYG-IGDPGETRDAVKASQT---PGPVV 13391
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLK 500
+K S++S S+ W++P G I+ Y V + E+ ++++ + L
Sbjct: 13392 DLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFL--TEENKWQRVMKSLSLQYSAKDLT 13449
Query: 501 PDTIYVFQIRARTAAGYGTNS 521
Y F++ A G GT S
Sbjct: 13450 EGKEYTFRVSAENENGEGTPS 13470
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 28/199 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + I++ S+++ W P++ GG + G+++++ E S +
Sbjct: 16928 PPGTP--FATAISKDSMVIQWHEPVNNGGSPVI---------GYHLERKERNSILWTKVN 16976
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T +L Y F + A N GV + S + A P P++
Sbjct: 16977 KTI-IHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMV 17035
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV-----TIS 497
RN I+L W +P + G ++ Y ++ ++A TNV T+S
Sbjct: 17036 ------KRNEITLQWTKPVYDGGSMI---TGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17086
Query: 498 SLKPDTIYVFQIRARTAAG 516
L D Y F++ A+ AAG
Sbjct: 17087 GLTEDQRYEFRVIAKNAAG 17105
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/203 (25%), Positives = 86/203 (42%), Gaps = 16/203 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PS+P+ + +I + SV L W P D GG +T ++ K+ S
Sbjct: 6991 PSAPKELKFGDITKDSVHLTWEPPDDDGG-SPLTGYVVEKR---------EVSRKTWTKV 7040
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
F +T+ TV DL+ Y F++ A N P V+++T P P +K
Sbjct: 7041 MDF-VTDLEFTVPDLVQGKEYLFKVCARNKCGP-GEPAYVDEPVNMSTPATVPDPPENVK 7098
Query: 445 -KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+DRT+ NSI L+W P++ G I Y V+ + + T + ++ L+
Sbjct: 7099 WRDRTA-NSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEG 7157
Query: 503 TIYVFQIRARTAAGYGTNSRKFE 525
Y ++++A G SR E
Sbjct: 7158 KWYAYRVKALNRQGASKPSRPTE 7180
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/199 (23%), Positives = 78/199 (39%), Gaps = 20/199 (10%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+++ +S+I S L W P D GG D + +K + K +P+
Sbjct: 9415 PGPPKDLKVSDITRGSCRLSWKMPDDDGG--DRIKGYVIEKRTIDGKAWTKVNPDCG--- 9469
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+TT V DLL+ Y F + A N + P + P P + +K
Sbjct: 9470 ------STTFVVPDLLSEQQYFFRVRAENRFG-IGPPVETIQRTTARDPIYPPDPPIKLK 9522
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYY------EKQEQETSYTILRARGTNVTIS 497
++N++ LSW+ P++ G + Y V+ K+E T+
Sbjct: 9523 IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9582
Query: 498 SLKPDTIYVFQIRARTAAG 516
L Y F+++A AAG
Sbjct: 9583 DLVEGGEYEFRVKAVNAAG 9601
Score = 43.9 bits (102), Expect = 4e-04
Identities = 48/201 (23%), Positives = 85/201 (42%), Gaps = 32/201 (15%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNVR 381
PP +P V++ + S+ + W+ P+ GG + + +++ K+ W +K + P +
Sbjct: 15846 PPGTP--VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILW-VKLNKTPIPQTK 15902
Query: 382 FLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSP 439
F T L Y F + A N G+ + S + A P
Sbjct: 15903 F------------KTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEA 15950
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVT 495
++ +RNS++L W++P + G I Y V+ E E + S+T T+
Sbjct: 15951 IIV------TRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT--NIIDTHFE 16002
Query: 496 ISSLKPDTIYVFQIRARTAAG 516
++ L D Y F++ AR AAG
Sbjct: 16003 VTGLVEDHRYEFRVIARNAAG 16023
Score = 43.9 bits (102), Expect = 4e-04
Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ S+ L W+ PL TGG + N I +K + S V
Sbjct: 16828 PPKGPVK-FDDVSAESITLSWNPPLYTGGCQ--ITNYIVQKRDTTTTVWDVVSATV---- 16880
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE---LSSPPRQFAAVSITTNQAAPSPVL 441
TT+ VT L T Y F I A N + L S P + P P
Sbjct: 16881 -----ARTTLKVTKLKTGTEYQFRIFAENRYGQSFALESDP-----IVAQYPYKEPGPPG 16930
Query: 442 TIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTIS 497
T S++S+ + W EP + G ++ Y ++ E+ + + TI+ T
Sbjct: 16931 TPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTII--HDTQFKAQ 16988
Query: 498 SLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPD 531
+L+ Y F++ A G G S+ E + D
Sbjct: 16989 NLEEGIEYEFRVYAENIVGVGKASKNSECYVARD 17022
Score = 43.9 bits (102), Expect = 4e-04
Identities = 45/193 (23%), Positives = 76/193 (39%), Gaps = 18/193 (9%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P+N+ + + + S L W P+ GG K + I ++ S +
Sbjct: 17619 PGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRE-----------STRKAYAN 17667
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T+ V +L Y F + A N + P AV PSP +
Sbjct: 17668 VSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-VGVPVETVDAVKAAE---PPSPPGKVT 17723
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDT 503
S+ S SL W++PEH G +L Y V+ K ++ S + ++ N ++ L
Sbjct: 17724 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWS-IVAESKVCNAVVTGLSSGQ 17782
Query: 504 IYVFQIRARTAAG 516
Y F+++A G
Sbjct: 17783 EYQFRVKAYNEKG 17795
Score = 43.9 bits (102), Expect = 4e-04
Identities = 44/206 (21%), Positives = 81/206 (39%), Gaps = 22/206 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ V++ W P TGG C+ + +++ + + +
Sbjct: 17910 PPVGPVR-FDEVSADFVVISWEPPAYTGG---------CQISNYIVEKRDTTTTTWHMVS 17959
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TT+ +T L T Y F I A N + S P AV + P P T
Sbjct: 17960 AT--VARTTIKITKLKTGTEYQFRIFAENRYGK--SAPLDSKAVIVQYPFKEPGPPGTPF 18015
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTI 504
S++ + + W EP + G + + Y+ +Q+++ S ++ T + + K +
Sbjct: 18016 VTSISKDQMLVQWHEPVNDGGTKI---IGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGL 18072
Query: 505 -----YVFQIRARTAAGYGTNSRKFE 525
Y F++ A G G S+ E
Sbjct: 18073 DEGLEYEFKVSAENIVGIGKPSKVSE 18098
Score = 43.9 bits (102), Expect = 4e-04
Identities = 49/235 (20%), Positives = 100/235 (42%), Gaps = 18/235 (7%)
Query: 295 STQEDGSMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGG 353
+++ED C +N + P ++ P P + I ++ S+ + W+ P GG
Sbjct: 18960 ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGG 19019
Query: 354 RKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN 413
C+ + +++ E S + + + T++ + L + Y F + A N
Sbjct: 19020 ---------CQISNYIVEKKETTSTTWHIVSQ--AVARTSIKIVRLTTGSEYQFRVCAEN 19068
Query: 414 GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEV 472
+ S + +AV + P P T K +++++ ++WQ P + G ++ Y +
Sbjct: 19069 RYGKSSYS--ESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHL 19126
Query: 473 KYYEKQE--QETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+Y E+ + IL A T + +S L +Y +++ A AG G S+ E
Sbjct: 19127 EYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCE 19180
Score = 43.9 bits (102), Expect = 4e-04
Identities = 56/224 (25%), Positives = 90/224 (40%), Gaps = 27/224 (12%)
Query: 317 PPSMACTRPPSSPRNVI--SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCE 374
P ++ PPS P+ I I SVIL W P D GG + I C ++I++ E
Sbjct: 21151 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGE-----ITC----YSIEKRE 21201
Query: 375 PCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITT 432
N + + + TT V +L+ Y F + A N GVS+ P + +
Sbjct: 21202 TSQTNWKMVCS--SVARTTFKVPNLVKDAEYQFRVRAENRYGVSQ----PLVSSIIVAKH 21255
Query: 433 NQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILR 488
P P + + +SL+W P + G + + V+ E+ Q+ + + +
Sbjct: 21256 QFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPIS 21315
Query: 489 ARGTNVTISSLKPDTIYVFQIRARTAAGYGTNS--RKFEFETSP 530
R T L Y F++ A +AG + S KF SP
Sbjct: 21316 GREYRAT--GLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSP 21357
Score = 43.5 bits (101), Expect = 5e-04
Identities = 51/207 (24%), Positives = 81/207 (39%), Gaps = 30/207 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P I I+ TS+ + W P GG G+ ++Q + P +LP
Sbjct: 23337 PPTGPIK-IDEIDATSITISWEPPELDGG---------APLSGYVVEQRDAHRPG--WLP 23384
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+T +T T L Y F + A N G+ Q + ++ P P T
Sbjct: 23385 VSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY----LQSEVIECRSSIRIPGPPET 23440
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE------QETSYTILRARGTNVT 495
++ SR+ ++L+W PE G + Y V+ E + + T+ R R T +T
Sbjct: 23441 LQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLT 23500
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSR 522
Y ++ A A G G SR
Sbjct: 23501 -----EGLEYEHRVTAINARGSGKPSR 23522
Score = 43.1 bits (100), Expect = 6e-04
Identities = 43/194 (22%), Positives = 81/194 (41%), Gaps = 14/194 (7%)
Query: 326 PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P NV I+++N V L W P GG ++T +I + +I+ + L
Sbjct: 6694 PGPPLNVTITDVNRFGVSLTWEPPEYDGGA-EITNYVIELRDKTSIRWDTAMTVRAEDL- 6751
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ TVTD++ Y+F + A N + + P V + PSP + +
Sbjct: 6752 --------SATVTDVVEGQEYSFRVRAQNRIG-VGKPSAATPFVKVADPIERPSPPVNLT 6802
Query: 445 KDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEK-QEQETSYTILRARGTNVTISSLKPD 502
+++S+ L W+ P G IL Y ++ E+ ++ + ++ L+
Sbjct: 6803 SSDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKG 6862
Query: 503 TIYVFQIRARTAAG 516
Y++++ A AG
Sbjct: 6863 NKYLYRVSAENKAG 6876
Score = 43.1 bits (100), Expect = 6e-04
Identities = 30/97 (30%), Positives = 46/97 (47%), Gaps = 17/97 (17%)
Query: 325 PPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNI-ICKKC--GWNIKQCEPCSPNV 380
PP P V +++ ++T+V L+WS P+ GG + + + I +CK W+ E C
Sbjct: 21756 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEAC---- 21811
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE 417
T TVTDL A Y F + A+NG +
Sbjct: 21812 ---------VKTRYTVTDLQAGEEYKFRVSAINGAGK 21839
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/210 (23%), Positives = 79/210 (37%), Gaps = 38/210 (18%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + + + +++ W PLD GG K + I K+ G ++ ++P
Sbjct: 10417 PPVGPVS-FDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDV-----------WMP 10464
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT V+ LL +Y F I A N G+S+ A A P++T
Sbjct: 10465 VTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVT 10524
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W +P I +Y EK+E + R VT + P
Sbjct: 10525 ----EVTKDSALVTWNKPHDGGKPITNY---ILEKRE------TMSKRWARVTKDPIHPY 10571
Query: 503 T-----------IYVFQIRARTAAGYGTNS 521
T Y F++ A G G S
Sbjct: 10572 TKFRVPDLLEGCQYEFRVSAENEIGIGDPS 10601
Score = 41.2 bits (95), Expect = 0.002
Identities = 48/204 (23%), Positives = 79/204 (38%), Gaps = 30/204 (14%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNII----CKKCGWNIKQCEPCSPNVRFLPRQFG 388
+S + + L WS P + GG ++T I+ + W I + E P + ++
Sbjct: 22652 VSRVTQEKCTLAWSLPQEDGG-AEITHYIVERRETSRLNWVIVEGE--CPTLSYV----- 22703
Query: 389 LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRT 448
VT L+ + Y F + AVN P + + + PSP ++ T
Sbjct: 22704 -------VTRLIKNNEYIFRVRAVNKYG--PGVPVESEPIVARNSFTIPSPPGIPEEVGT 22754
Query: 449 SRNSISLSWQEPEHPNG-IILDYEVKYYEKQ-----EQETSYTILRARGTNVTISSLKPD 502
+ I + W +PE G I +Y V EK+ Y + T + ++SL
Sbjct: 22755 GKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVY---DTRLKVTSLMEG 22811
Query: 503 TIYVFQIRARTAAGYGTNSRKFEF 526
Y F++ A AAG S F
Sbjct: 22812 CDYQFRVTAVNAAGNSEPSEASNF 22835
Score = 40.4 bits (93), Expect = 0.004
Identities = 47/205 (22%), Positives = 82/205 (40%), Gaps = 34/205 (16%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WNIKQCEPCSPNV 380
PPS+P R + +++ ++ + W P GG K + + + K+ W + PC
Sbjct: 22343 PPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPC---- 22398
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
VT L+ Y F A+N GVS+ S R A + P
Sbjct: 22399 ---------LECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPE 22449
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQ------ETSYTILRARG 491
+R+++SL W P + G ++ Y ++ E + +YTI+
Sbjct: 22450 VT------DVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVS--D 22501
Query: 492 TNVTISSLKPDTIYVFQIRARTAAG 516
T+++L Y F++ A+ AAG
Sbjct: 22502 NFFTVTALSEGDTYEFRVLAKNAAG 22526
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/189 (23%), Positives = 77/189 (40%), Gaps = 16/189 (8%)
Query: 334 SNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTT 393
SNI S+ L W+ P GG + + + ++ + + V+ + ++ ++ T
Sbjct: 21664 SNITGNSITLTWARPESDGGSEIQQYILERRE--------KKSTRWVKVISKR-PISETR 21714
Query: 394 VTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
VT L Y F + A N GV S R + P P +K TS+
Sbjct: 21715 FKVTGLTEGNEYEFHVMAENAAGVGPASGISR---LIKCREPVNPPGPPTVVKVTDTSKT 21771
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTISSLKPDTIYVFQI 509
++SL W +P G+ I+ Y ++ + + A T T++ L+ Y F++
Sbjct: 21772 TVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRV 21831
Query: 510 RARTAAGYG 518
A AG G
Sbjct: 21832 SAINGAGKG 21840
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/204 (25%), Positives = 85/204 (41%), Gaps = 28/204 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P+ + + S+++ W+ PLD GG +T G+ +++ E SP +
Sbjct: 9104 PPGKPKVLART--KGSMLVSWTPPLDNGG-SPIT--------GYWLEKREEGSPYWSRVS 9152
Query: 385 R----QFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPS-- 438
R + GL V LL Y F A+N PP + + + + P
Sbjct: 9153 RAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAG--IGPPSEPSDPEVAGDPIFPPGP 9210
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT-- 495
P KD+T ++SISL W+ P G I Y V+ E E T + + +T
Sbjct: 9211 PSCPEVKDKT-KSSISLGWKPPAKDGGSPIKGYIVEMQE--EGTTDWKRVNEPDKLITTC 9267
Query: 496 ---ISSLKPDTIYVFQIRARTAAG 516
+ +LK Y F+++A AG
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAG 9291
Score = 38.9 bits (89), Expect = 0.012
Identities = 47/197 (23%), Positives = 85/197 (43%), Gaps = 25/197 (12%)
Query: 333 ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP-RQFGLTN 391
++ +++ + + W+ P GG K +T G+ +++ E S R++P + +
Sbjct: 11907 VTKVSKEEMTVVWNPPEYDGG-KSIT--------GYFLEKKEKHS--TRWVPVNKSAIPE 11955
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
+ V +LL Y F + A N G+ E S P R A P P + T+
Sbjct: 11956 RRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIE---PPGPPTNFRVVDTT 12012
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEK---QEQETSYTILRARGTNV----TISSLKP 501
++SI+L W +P + G I+ Y V+ K + + A V T++SL
Sbjct: 12013 KHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDE 12072
Query: 502 DTIYVFQIRARTAAGYG 518
+ Y F++ A+ G G
Sbjct: 12073 NQEYEFRVCAQNQVGIG 12089
Score = 38.9 bits (89), Expect = 0.012
Identities = 32/114 (28%), Positives = 51/114 (44%), Gaps = 16/114 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P + ++ ++ L W+ PL GG K V ++I E N R++
Sbjct: 21360 PPGTPDYI--DVTRETITLKWNPPLRDGGSKIVGYSI------------EKRQGNERWVR 21405
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
F ++ TVT L Y F I A N V + SPP Q + + +T ++ P
Sbjct: 21406 CNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTI-SPPSQSSGIIMTRDENVP 21458
Score = 38.5 bits (88), Expect = 0.016
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P V NI +V L W+ P TGG K +T I+ K+ PN R+L
Sbjct: 14862 PPGKP--VPLNITRHTVTLKWAKPEYTGGFK-ITSYIVEKRD----------LPNGRWLK 14908
Query: 385 RQFG-LTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + TV+ L Y F + A N +S P A++ + AP + +
Sbjct: 14909 ANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDV 14968
Query: 444 K 444
K
Sbjct: 14969 K 14969
Score = 38.5 bits (88), Expect = 0.016
Identities = 30/111 (27%), Positives = 51/111 (45%), Gaps = 13/111 (11%)
Query: 329 PRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQF 387
PRNV I++I++ SV L W P GG K +T I+ ++ P+ R+ F
Sbjct: 20274 PRNVRITDISKNSVSLSWQQPAFDGGSK-ITGYIVERRD----------LPDGRWTKASF 20322
Query: 388 -GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
+T T ++ L ++ Y F + A N V +S+P ++ + P
Sbjct: 20323 TNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGP 20373
Score = 38.5 bits (88), Expect = 0.016
Identities = 42/194 (21%), Positives = 77/194 (39%), Gaps = 27/194 (13%)
Query: 332 VISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTN 391
VI + + S ++ W P D GG N + +KC + ++
Sbjct: 24234 VIEALLKNSAVISWKPPADDGG--SWITNYVVEKC--------EAKEGAEWQLVSSAISV 24283
Query: 392 TTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQ-----AAPSPVLTIK 444
TT + +L + Y F + A N G+S+ P + ++V I + A P +T
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISD----PLEVSSVVIIKSPFEKPGAPGKPTIT-- 24337
Query: 445 KDRTSRNSISLSWQEPEHPNGIILD--YEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+++S ++W+ P G + Y K +KQ + S T R T ++ +L
Sbjct: 24338 --AVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEG 24395
Query: 503 TIYVFQIRARTAAG 516
Y F+++ G
Sbjct: 24396 LEYEFRVKCENLGG 24409
Score = 38.1 bits (87), Expect = 0.021
Identities = 50/205 (24%), Positives = 89/205 (43%), Gaps = 28/205 (13%)
Query: 326 PSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPR 385
P +P ++ + + S+I+ W P GG + + + ++ K+ I+ R R
Sbjct: 16243 PKAPE--VTTVTKDSMIVVWERPASDGGSEILGY-VLEKRDKEGIRW-------TRCHKR 16292
Query: 386 QFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
G + VT L+ + +Y F + A N G+SE SPP + + P P
Sbjct: 16293 LIG--ELRLRVTGLIENHDYEFRVSAENAAGLSE-PSPPSAYQKACDPIYK--PGPPNNP 16347
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILR----ARGTNVTI 496
K +R+S+ LSW +P + G E++ Y ++ + S +T+ TN+ +
Sbjct: 16348 KVIDITRSSVFLSWSKPIYDGGC----EIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEV 16403
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNS 521
L Y F+I A AG G ++
Sbjct: 16404 EKLLEKHEYNFRICAINKAGVGEHA 16428
Score = 38.1 bits (87), Expect = 0.021
Identities = 31/121 (25%), Positives = 50/121 (41%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++NI SV L WS P GG K G+ +++ E P+ R+L
Sbjct: 19190 PPGQPE--VTNITRKSVSLKWSKPHYDGGAKIT---------GYIVERRE--LPDGRWLK 19236
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + T VT+L Y F + A N +S P + + + P ++ +
Sbjct: 19237 CNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDV 19296
Query: 444 K 444
K
Sbjct: 19297 K 19297
Score = 37.7 bits (86), Expect = 0.027
Identities = 39/151 (25%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PPS P + V+++I E + + W+ P GG +T G+ +++ E VR
Sbjct: 11206 PPSPPGKPVVTDITENAATVSWTLPKSDGG-SPIT--------GYYMERREVTGKWVRV- 11255
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
+ + + VT L Y F + A N ++ LS P + P P +
Sbjct: 11256 -NKTPIADLKFRVTGLYEGNTYEFRVFAEN-LAGLSKPSPSSDPIKACRPIKPPGPPINP 11313
Query: 444 KKDRTSRNSISLSWQEPEHPNGI-ILDYEVK 473
K SR + L W +P G IL Y V+
Sbjct: 11314 KLKDKSRETADLVWTKPLSDGGSPILGYVVE 11344
Score = 37.7 bits (86), Expect = 0.027
Identities = 29/130 (22%), Positives = 55/130 (42%), Gaps = 9/130 (6%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T+T + + + + + + + A N V E+ ++I + P IK D S
Sbjct: 14622 TSTILNINECVRSDSGPYPLTARNIVGEVGD------VITIQVHDIPGPPTGPIKFDEVS 14675
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+ ++ SW PE+ G+ I +Y V+ +Q T++ L T + + T +Q
Sbjct: 14676 SDFVTFSWDPPENDGGVPISNYVVEM--RQTDSTTWVELATTVIRTTYKATRLTTGLEYQ 14733
Query: 509 IRARTAAGYG 518
R + YG
Sbjct: 14734 FRVKAQNRYG 14743
Score = 37.4 bits (85), Expect = 0.035
Identities = 40/200 (20%), Positives = 75/200 (37%), Gaps = 25/200 (12%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKK---CGWNIKQCEPCSPNV 380
RP ++N+ + + + W PLD GG + F + +K GW+I + +
Sbjct: 11504 RPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI 11563
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPS 438
+ +LLA+ Y F + A N GV A++ P
Sbjct: 11564 K---------------ANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPE 11608
Query: 439 PVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA-RGTNVTI 496
+ K +T + L W+ P++ G L Y V+ K + + + T+ +
Sbjct: 11609 NLHIADKGKT---FVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMV 11665
Query: 497 SSLKPDTIYVFQIRARTAAG 516
+ IY F+++ + G
Sbjct: 11666 DRCVENQIYEFRVQTKNEGG 11685
Score = 37.4 bits (85), Expect = 0.035
Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 9/132 (6%)
Query: 395 TVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T L+ Y F + AVN GV A + T A P + + NS
Sbjct: 21615 TAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP----EPSNITGNS 21670
Query: 453 ISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRA--RGTNVTISSLKPDTIYVFQI 509
I+L+W PE G I Y ++ EK+ I + T ++ L Y F +
Sbjct: 21671 ITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21730
Query: 510 RARTAAGYGTNS 521
A AAG G S
Sbjct: 21731 MAENAAGVGPAS 21742
Score = 37.0 bits (84), Expect = 0.046
Identities = 33/121 (27%), Positives = 48/121 (39%), Gaps = 14/121 (11%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P ++ I +V L W P GG K +T I+ KK P+ R++
Sbjct: 18108 PPGRPEAIV--ITRNNVTLKWKKPAYDGGSK-ITGYIVEKKD----------LPDGRWMK 18154
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + T TV+ L+ Y F + A N S P A++ AP+ L
Sbjct: 18155 ASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDP 18214
Query: 444 K 444
K
Sbjct: 18215 K 18215
Score = 37.0 bits (84), Expect = 0.046
Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 10/133 (7%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T T++++ + T+E+ N ++ P + + P P I+ D S
Sbjct: 18951 TVTSLSIKEASKEDVGTYELCVSNSAGSITVP----ITIIVLDRPGPPGP---IRIDEVS 19003
Query: 450 RNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQ 508
+SI++SW PE+ G I +Y V+ +K+ T++ I+ +I ++ T +Q
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVE--KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQ 19061
Query: 509 IRARTAAGYGTNS 521
R YG +S
Sbjct: 19062 FRVCAENRYGKSS 19074
Score = 37.0 bits (84), Expect = 0.046
Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 20/201 (9%)
Query: 324 RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRF 382
R P P + I +++ + L W P D GG + VT I+ +K ++ N
Sbjct: 23433 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQ-VTGYIVERK---EVRADRWVRVN--- 23485
Query: 383 LPRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAP-SP 439
+ +T T T L Y + A+N G + S P + A+ P +P
Sbjct: 23486 ---KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNP 23542
Query: 440 VLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE-TSYTILRARGTNVTIS 497
+T T+R S+SL+W PE G + Y ++ + + E T + T++
Sbjct: 23543 RVT----DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLT 23598
Query: 498 SLKPDTIYVFQIRARTAAGYG 518
L Y F++ A A G G
Sbjct: 23599 HLPQGAEYRFRVLACNAGGPG 23619
Score = 36.6 bits (83), Expect = 0.060
Identities = 37/127 (29%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P + NI SV L W+ P GG K +T I+ K+ P+ ++
Sbjct: 13779 PPGKPE--VINITRNSVTLIWTEPKYDGGHK-LTGYIVEKRD----------LPSKSWMK 13825
Query: 385 -RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVL-- 441
+ TVTDL+ Y F I A N +S+P + AP+ VL
Sbjct: 13826 ANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDP 13885
Query: 442 TIKKDRT 448
TIK T
Sbjct: 13886 TIKDGLT 13892
Score = 36.2 bits (82), Expect = 0.078
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PV +K ++ S +SW PE+ G + Y V+ E + S + T+
Sbjct: 12202 PGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTSFH 12261
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+++L P Y F++ A G G
Sbjct: 12262 VTNLVPGNEYYFRVTAVNEYGPG 12284
Score = 35.4 bits (80), Expect = 0.13
Identities = 47/214 (21%), Positives = 78/214 (36%), Gaps = 26/214 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP+ P + + S+ L W P GG N I +K + + S V
Sbjct: 15746 PPTGPVKM-DEVTADSITLSWGPPKYDGGSS--INNYIVEKRDTSTTTWQIVSATV---- 15798
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
TT+ L Y F I A N G S + A +PV+T
Sbjct: 15799 -----ARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVT 15853
Query: 443 IKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPD 502
+ +SR+S+ + W EP G + Y+ ++++ S ++ T + + K
Sbjct: 15854 L----SSRDSMEVQWNEPISDGG---SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTT 15906
Query: 503 TI-----YVFQIRARTAAGYGTNSRKFEFETSPD 531
+ Y F++ A G G S+ E + D
Sbjct: 15907 GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 15940
Score = 35.4 bits (80), Expect = 0.13
Identities = 24/89 (26%), Positives = 37/89 (41%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTI 496
P P +K SR+S++L+W EP G + + E + +AR T T+
Sbjct: 24625 PDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRVGQARETRYTV 24684
Query: 497 SSLKPDTIYVFQIRARTAAGYGTNSRKFE 525
+L T Y F++ A G S E
Sbjct: 24685 INLFGKTSYQFRVIAENKFGLSKPSEPSE 24713
Score = 35.0 bits (79), Expect = 0.17
Identities = 28/119 (23%), Positives = 52/119 (43%), Gaps = 12/119 (10%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +++ + T++ L+W P GG + V + + + G N + C+ +
Sbjct: 8505 PPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN--EWSRCTEKM-IKV 8561
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
RQ+ TV ++ +Y + AVN E PP + V++ Q P+ L +
Sbjct: 8562 RQY-------TVKEIREGADYKLRVSAVNAAGE--GPPGETQPVTVAEPQEPPAVELDV 8611
Score = 35.0 bits (79), Expect = 0.17
Identities = 37/167 (22%), Positives = 68/167 (40%), Gaps = 21/167 (12%)
Query: 305 RCENNYFRADK-DPPSMACTRP---PSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
R EN + ++ P M P PS P+N ++ +N+ + + W P GG + +
Sbjct: 12570 RAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGY 12629
Query: 360 NIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGV-SEL 418
+I +K ++ + VR +T L+ Y+F I A+N S
Sbjct: 12630 -LIERKERNSLLWVKANDTLVR---------STEYPCAGLVEGLEYSFRIYALNKAGSSP 12679
Query: 419 SSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNG 465
S P ++ + + V+ + K +++SL W P+H G
Sbjct: 12680 PSKPTEYVTARMPVDPPGKPEVIDVTK-----STVSLIWARPKHDGG 12721
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/200 (24%), Positives = 76/200 (38%), Gaps = 25/200 (12%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP P +I + SV L W P GG K +T I+ KK P R++
Sbjct: 15944 PPGRPEAII--VTRNSVTLQWKKPTYDGGSK-ITGYIVEKKE----------LPEGRWMK 15990
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
F + +T VT L+ Y F + A N S P A++ P I
Sbjct: 15991 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPP----RI 16046
Query: 444 KKDRTSRNSISLSWQEPEHPNGIILDYEVKYYE--KQEQETSYTI-LRARGTNVTISSLK 500
D +++I + E + I + + K +QE S T L + T+ S
Sbjct: 16047 SMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSLSV 16106
Query: 501 PDTIYV----FQIRARTAAG 516
D + V + ++A+ AG
Sbjct: 16107 KDAVRVDSGNYILKAKNVAG 16126
Score = 34.7 bits (78), Expect = 0.23
Identities = 42/197 (21%), Positives = 83/197 (42%), Gaps = 26/197 (13%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P+ V + ++++++ W P++ GG + + +++ K+ S +
Sbjct: 19092 PPGTPKVV--HATKSTMLVTWQVPVNDGGSRVIGYHLEYKER----------SSILWSKA 19139
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLT 442
+ + +T + V+ L Y + + A N G+ + S A P
Sbjct: 19140 NKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVT-- 19197
Query: 443 IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISS 498
+R S+SL W +P + G I Y V+ E + + +YT ++ T ++
Sbjct: 19198 ----NITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQE--TYFEVTE 19251
Query: 499 LKPDTIYVFQIRARTAA 515
L D Y F++ AR AA
Sbjct: 19252 LTEDQRYEFRVFARNAA 19268
Score = 34.7 bits (78), Expect = 0.23
Identities = 31/127 (24%), Positives = 51/127 (40%), Gaps = 14/127 (11%)
Query: 317 PPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEP 375
P + T P+ PR + + + +++S +L W P GG + + + ++ G +
Sbjct: 22040 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSD------ 22093
Query: 376 CSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQA 435
F T TV L+ T Y F + A N S P F++V I Q
Sbjct: 22094 ------FWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAG-YSEPREAFSSVIIKEPQI 22146
Query: 436 APSPVLT 442
P+ LT
Sbjct: 22147 EPTADLT 22153
Score = 34.3 bits (77), Expect = 0.30
Identities = 22/83 (26%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P IK +++S L+W+ PE G IL Y ++ E + + + T
Sbjct: 7983 PGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWT 8042
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
+ L P+ Y F+++A G G
Sbjct: 8043 VKDLIPNGEYFFRVKAVNKVGGG 8065
Score = 34.3 bits (77), Expect = 0.30
Identities = 39/183 (21%), Positives = 70/183 (38%), Gaps = 18/183 (9%)
Query: 337 NETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTV 396
N +L+WS P D GG ++T II +K +P + +
Sbjct: 8712 NRKMCLLNWSDPEDDGG-SEITGFIIERKDAKMHTWRQPIETE-----------RSKCDI 8759
Query: 397 TDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLS 456
T LL Y F + A N PP + + P+ + ++++I+L
Sbjct: 8760 TGLLEGQEYKFRVIAKNKFG--CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8817
Query: 457 WQEPEHPNGIILD---YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRART 513
W+EP G + E + ++K + E L T+ + +L +Y F+++A
Sbjct: 8818 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRL-CPTTSFLVENLDEHQMYEFRVKAVN 8876
Query: 514 AAG 516
G
Sbjct: 8877 EIG 8879
Score = 34.3 bits (77), Expect = 0.30
Identities = 21/83 (25%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P ++K SR+S++++W+ P G + +Y V+ E + + T
Sbjct: 23041 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYR 23100
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
IS L T+Y F++ G G
Sbjct: 23101 ISGLVEGTMYYFRVLPENIYGIG 23123
Score = 33.9 bits (76), Expect = 0.39
Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 7/129 (5%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T + + + D L + + I A N +FAA + P PVL +K T+
Sbjct: 8660 TKSELIIKDALRKDHGRYVITATNSCGS------KFAAARVEVFDV-PGPVLDLKPVVTN 8712
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
R L+W +PE G + + + + T + + I+ L Y F++
Sbjct: 8713 RKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRV 8772
Query: 510 RARTAAGYG 518
A+ G G
Sbjct: 8773 IAKNKFGCG 8781
Score = 33.9 bits (76), Expect = 0.39
Identities = 22/66 (33%), Positives = 31/66 (46%), Gaps = 1/66 (1%)
Query: 301 SMNCRCENNYFRADKDPPSMACTRPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTF 359
++N R R K +M PP P+N +++ TSV L WS P D GG K +
Sbjct: 23511 AINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGY 23570
Query: 360 NIICKK 365
I +K
Sbjct: 23571 LIEMQK 23576
Score = 33.5 bits (75), Expect = 0.51
Identities = 39/194 (20%), Positives = 79/194 (40%), Gaps = 17/194 (8%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
P P + ++ SV + W P GG N I +K ++ + +
Sbjct: 23041 PGPCPSVKVKEVSRDSVTITWEIPTIDGGAP--VNNYIVEKREAAMRAFKTVTTKC---- 23094
Query: 385 RQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIK 444
+ T ++ L+ T Y F + N + + P AV ++ P+ + +
Sbjct: 23095 -----SKTLYRISGLVEGTMYYFRVLPEN-IYGIGEPCETSDAVLVSEVPLVPAKLEVVD 23148
Query: 445 KDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNV--TISSLKPD 502
++++++L+W++P + G L V K E ++ + T + T++SL
Sbjct: 23149 ---VTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVTSLNEG 23205
Query: 503 TIYVFQIRARTAAG 516
Y+F+IRA+ G
Sbjct: 23206 EQYLFRIRAQNEKG 23219
Score = 33.1 bits (74), Expect = 0.66
Identities = 41/160 (25%), Positives = 67/160 (41%), Gaps = 18/160 (11%)
Query: 325 PPSSP-RNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
PP+SP R + ++++ LDW P GG G+ I++ P+ +
Sbjct: 8797 PPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQ---------GYIIEKRRHDKPDFERV 8847
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTI 443
++ T T+ V +L H Y F + AVN + E S P V I ++ P TI
Sbjct: 8848 NKRLCPT-TSFLVENLDEHQMYEFRVKAVNEIGE--SEPSLPLNVVIQDDEVPP----TI 8900
Query: 444 KKDRTSR-NSISLSWQEPEHPNGIILDYEVKYYEKQEQET 482
K + R ++I + EP H + + E + ET
Sbjct: 8901 KLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNET 8940
Score = 32.7 bits (73), Expect = 0.86
Identities = 26/129 (20%), Positives = 52/129 (40%), Gaps = 7/129 (5%)
Query: 391 NTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSR 450
++ +T+ + L ++I N + AV +T P I +
Sbjct: 11068 SSVLTIKNCLRRDTGEYQITVSNAAGSKT------VAVHLTVLDVPGPPTGPINILDVTP 11121
Query: 451 NSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQI 509
+++SWQ P+ G +++Y V+ + ++ + T + I L+ YVF++
Sbjct: 11122 EHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRV 11181
Query: 510 RARTAAGYG 518
RA G G
Sbjct: 11182 RAENKIGVG 11190
Score = 32.7 bits (73), Expect = 0.86
Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 1/83 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P PVL ++ +++S++L W P G I +Y V+ E + S +
Sbjct: 14371 PGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYK 14430
Query: 496 ISSLKPDTIYVFQIRARTAAGYG 518
++ L Y F++ A G G
Sbjct: 14431 VTGLSEGCEYFFRVMAENEYGIG 14453
Score = 32.7 bits (73), Expect = 0.86
Identities = 36/138 (26%), Positives = 52/138 (37%), Gaps = 8/138 (5%)
Query: 392 TTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRN 451
TT T L Y F + A N P A + P P T + +++
Sbjct: 14719 TTYKATRLTTGLEYQFRVKAQNRYGV--GPGITSACIVANYPFKVPGPPGTPQVTAVTKD 14776
Query: 452 SISLSWQEPEHPNGI-ILDYEVKYYEKQE---QETSYTILRARGTNVTISSLKPDTIYVF 507
S+++SW EP G IL Y V+ E+ Q S ++ G S L Y F
Sbjct: 14777 SMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALV--PGNIFKSSGLTDGIAYEF 14834
Query: 508 QIRARTAAGYGTNSRKFE 525
++ A AG S+ E
Sbjct: 14835 RVIAENMAGKSKPSKPSE 14852
Score = 32.3 bits (72), Expect = 1.1
Identities = 40/151 (26%), Positives = 58/151 (38%), Gaps = 37/151 (24%)
Query: 318 PSMACT--RPPSSPRNV-ISNINETSVILDWSWPLDTGGRKDVTFNIICKKCG---WN-- 369
P AC +PP P N + + + + L W+ PL GG + + + C+K G WN
Sbjct: 11297 PIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRI 11356
Query: 370 -----IKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQ 424
I+QC V L+ Y F I A N V E PR+
Sbjct: 11357 NKDELIRQC-------------------AFRVPGLIEGNEYRFRIKAANIVGE--GEPRE 11395
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISL 455
A I + P V + D T R+ I++
Sbjct: 11396 LAESVIAKDILHPPEV---ELDVTCRDVITV 11423
Score = 32.3 bits (72), Expect = 1.1
Identities = 24/99 (24%), Positives = 39/99 (39%), Gaps = 9/99 (9%)
Query: 425 FAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSY 484
F A + P PV +K S + ++ W PE G E++ Y ++ ET
Sbjct: 11788 FVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGC----EIQNYILEKCETKR 11843
Query: 485 TILRARGTNV-----TISSLKPDTIYVFQIRARTAAGYG 518
+ V T++ L Y+F++RA G G
Sbjct: 11844 MVWSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTG 11882
Score = 31.6 bits (70), Expect = 1.9
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 14/98 (14%)
Query: 325 PPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLP 384
PP +P ++ NE + L W+ P+ GG +T I+ K+ P+ R++
Sbjct: 17026 PPGTPEPIMVKRNE--ITLQWTKPVYDGGSM-ITGYIVEKRD----------LPDGRWMK 17072
Query: 385 RQF-GLTNTTVTVTDLLAHTNYTFEIDAVNGVSELSSP 421
F + T TV+ L Y F + A N +S P
Sbjct: 17073 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKP 17110
Score = 30.8 bits (68), Expect = 3.3
Identities = 25/87 (28%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 437 PSPVLT-IKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQE---TSYTILRARG 491
P PV T + S L+W PE G I +Y ++ E + +YT+ R
Sbjct: 10119 PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQ-- 10176
Query: 492 TNVTISSLKPDTIYVFQIRARTAAGYG 518
N T+ L Y F+I A + G G
Sbjct: 10177 -NATVQGLIQGKAYFFRIAAENSIGMG 10202
Score = 30.4 bits (67), Expect = 4.3
Identities = 23/99 (23%), Positives = 38/99 (38%), Gaps = 1/99 (1%)
Query: 437 PSPVLTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETSYTILRARGTNVT 495
P P +K +R S LSW+ P+ G I Y ++ + + T
Sbjct: 9415 PGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFV 9474
Query: 496 ISSLKPDTIYVFQIRARTAAGYGTNSRKFEFETSPDCMY 534
+ L + Y F++RA G G + T+ D +Y
Sbjct: 9475 VPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIY 9513
Score = 30.0 bits (66), Expect = 5.6
Identities = 25/95 (26%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 426 AAVSITTNQAAPSPV-LTIKKDRTSRNSISLSWQEPEHPNGI-ILDYEVKYYEKQEQETS 483
A V++ + +PV LTI++ ++S++LSW+ P G I +Y V+ E + +
Sbjct: 18692 AFVNVRVLDSPSAPVNLTIRE--VKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18749
Query: 484 YTILRARGTNVTISSLKPDTIYVFQIRARTAAGYG 518
T I +L+ Y F++ A G G
Sbjct: 18750 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIG 18784
Score = 29.6 bits (65), Expect = 7.3
Identities = 20/88 (22%), Positives = 41/88 (46%), Gaps = 9/88 (10%)
Query: 436 APSPVLTIKKDRTSRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETS---YTILRARGT 492
+P P + R ++ +L+W P+ G E+ +Y + +ETS + I+
Sbjct: 22643 SPGPCGKLTVSRVTQEKCTLAWSLPQEDGGA----EITHYIVERRETSRLNWVIVEGECP 22698
Query: 493 NVT--ISSLKPDTIYVFQIRARTAAGYG 518
++ ++ L + Y+F++RA G G
Sbjct: 22699 TLSYVVTRLIKNNEYIFRVRAVNKYGPG 22726
Score = 29.6 bits (65), Expect = 7.3
Identities = 28/128 (21%), Positives = 44/128 (34%), Gaps = 9/128 (7%)
Query: 393 TVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNS 452
T+ T + YT E+ V G + + + P IK D S
Sbjct: 23300 TIRETTIRDTGEYTLELKNVTGTTS--------ETIKVIILDKPGPPTGPIKIDEIDATS 23351
Query: 453 ISLSWQEPEHPNGIILD-YEVKYYEKQEQETSYTILRARGTNVTISSLKPDTIYVFQIRA 511
I++SW+ PE G L Y V+ + + + L YVF++ A
Sbjct: 23352 ITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAA 23411
Query: 512 RTAAGYGT 519
G G+
Sbjct: 23412 TNRFGIGS 23419
Score = 29.6 bits (65), Expect = 7.3
Identities = 46/217 (21%), Positives = 84/217 (38%), Gaps = 33/217 (15%)
Query: 324 RPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFL 383
+P + + I+ + + S ++ W P GG K + + ++ N K + +R
Sbjct: 24327 KPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQN-KWISVTTEEIR-- 24383
Query: 384 PRQFGLTNTTVTVTDLLAHTNYTFEIDAVN--GVSELSSPPRQFAAVSITTNQAAPSPVL 441
T +V +L+ Y F + N G SE S + IT P
Sbjct: 24384 -------ETVFSVKNLIEGLEYEFRVKCENLGGESEWSE-----ISEPITPKSDVPIQAP 24431
Query: 442 TIKKDRTSRN-----SISLSWQEPEHPNGIILDYEVKYYEKQEQETS----YTILRARGT 492
K++ + N + +L + HP I VK+Y + ++ + Y I +G
Sbjct: 24432 HFKEELRNLNVRYQSNATLVCKVTGHPKPI-----VKWYRQGKEIIADGLKYRIQEFKGG 24486
Query: 493 --NVTISSLKPDTIYVFQIRARTAAGYGTNSRKFEFE 527
+ I+S+ D V+Q+RA G + + E E
Sbjct: 24487 YHQLIIASVTDDDATVYQVRATNQGGSVSGTASLEVE 24523
Score = 29.3 bits (64), Expect = 9.5
Identities = 38/158 (24%), Positives = 59/158 (37%), Gaps = 20/158 (12%)
Query: 286 KCAKCPPHSSTQEDGS---MNCRCENNYFRADKDPPS--MACTRPPSSPRNV-ISNINET 339
KC KC + +G EN Y + + + + PS P ++ I +I ++
Sbjct: 14423 KCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKS 14482
Query: 340 SVILDWSWPLDTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDL 399
+V L W P GG K + I ++ G S + GL V +L
Sbjct: 14483 TVSLAWPKPKHDGGSKITGYVIEAQRKG---------SDQWTHITTVKGL---ECVVRNL 14530
Query: 400 LAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAP 437
YTF++ AVN S PR+ V + P
Sbjct: 14531 TEGEEYTFQVMAVNSAGR--SAPRESRPVIVKEQTMLP 14566
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 62.8 bits (151), Expect = 8e-10
Identities = 66/247 (26%), Positives = 107/247 (43%), Gaps = 32/247 (12%)
Query: 298 EDGSMNCRCENNYFRADKDPPSM------ACTRP-PSSPRNVISNINETSVI-LDWSWPL 349
++G C EN+ A + A T P PS+PR+V++++ T I L W P
Sbjct: 404 DEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPA 463
Query: 350 DTGGRKDVTFNIICKKCGWNIKQCEPCSPNVRFLPRQFGLTNTTVTVTDLLAHTNYTFEI 409
++T+++ K G ++ E S P + VT+ +L+ T Y F +
Sbjct: 464 SDPHGDNLTYSVFYTKEGIARERVENTSH-----PGEM-----QVTIQNLMPATVYIFRV 513
Query: 410 DAVN--GVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTSRNSISLSWQEPEHPNGII 467
A N G E S+P R V P P ++ S SI+++W+ P NG I
Sbjct: 514 MAQNKHGSGESSAPLR----VETQPEVQLPGPAPNLRAYAASPTSITVTWETPVSGNGEI 569
Query: 468 LDYEVKYYEK---QEQETSYTILRARGTNVTISSLKPDTIYVFQIRARTAAGYGTNSRKF 524
+Y++ Y EK +EQ+ + + TI+ LK T Y F++ A G G ++
Sbjct: 570 QNYKLYYMEKGTDKEQDVDVS-----SHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDV 624
Query: 525 EFETSPD 531
T D
Sbjct: 625 AVRTLSD 631
Score = 46.2 bits (108), Expect = 8e-05
Identities = 38/142 (26%), Positives = 56/142 (39%), Gaps = 4/142 (2%)
Query: 390 TNTTVTVTDLLAHTNYTFEIDAVNGVSELSSPPRQFAAVSITTNQAAPSPVLTIKKDRTS 449
T + VT L +T Y F + G + + P V + K+
Sbjct: 911 TTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKP 970
Query: 450 RNSISLSWQEPEHPNGIILDYEVKYYEKQEQET-SYTILRARGTNVT--ISSLKPDTIYV 506
+ +I ++WQ P NG I Y + Y E + I G +T I L DT Y
Sbjct: 971 K-TIIVNWQPPSEANGKITGYIIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYY 1029
Query: 507 FQIRARTAAGYGTNSRKFEFET 528
F+I+AR + G G S +F T
Sbjct: 1030 FKIQARNSKGMGPMSEAVQFRT 1051
Score = 35.8 bits (81), Expect = 0.10
Identities = 48/236 (20%), Positives = 93/236 (39%), Gaps = 45/236 (19%)
Query: 323 TRPPSSPRNVISNINETSVILDWSWPLDTGGRKDVTFNIICK--KCGWNIKQCEPCSPNV 380
TR P P ++ TS+++ W+ P + NI+ + G+ I + V
Sbjct: 736 TRVPEVPSSLHVRPLVTSIVVSWTPPENQ--------NIVVRGYAIGYGIGSPHAQTIKV 787
Query: 381 RFLPRQFGLTNTTVTVTDLLAHTNYTFEIDAVNGVSE--------LSSPPRQFAAVSITT 432
+ R + T+ +L ++Y + A N V E ++ P + V +
Sbjct: 788 DYKQRYY-------TIENLDPSSHYVITLKAFNNVGEGIPLYESAVTRPHTDTSEVDLFV 840
Query: 433 NQAAPSPV---------LTIKKDRTSRNSISLSWQE---PEHPNGIILD---YEVKYYEK 477
A +PV + ++ S ++I ++W + P+H I D Y V++
Sbjct: 841 INAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQK--ITDSRYYTVRWKTN 898
Query: 478 QEQETSYTILRARGTNVTISSLKPDTIYVFQI---RARTAAGYGTNSRKFEFETSP 530
T Y A + ++ LKP+T+Y F + + R ++ + + FE P
Sbjct: 899 IPANTKYKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVP 954
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,339,411
Number of Sequences: 37866
Number of extensions: 1039282
Number of successful extensions: 4388
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 96
Number of HSP's successfully gapped in prelim test: 135
Number of HSP's that attempted gapping in prelim test: 2581
Number of HSP's gapped (non-prelim): 1249
length of query: 539
length of database: 18,247,518
effective HSP length: 107
effective length of query: 432
effective length of database: 14,195,856
effective search space: 6132609792
effective search space used: 6132609792
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.