Search of human proteins with 123173757

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|123173757 RAVER1 [Homo sapiens]
         (756 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|123173757 RAVER1 [Homo sapiens]                                   1538   0.0  
gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]           423   e-118
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    71   3e-12
gi|109240550 paraspeckle protein 1 [Homo sapiens]                      69   2e-11
gi|224028246 non-POU domain containing, octamer-binding isoform ...    69   2e-11
gi|224028244 non-POU domain containing, octamer-binding isoform ...    69   2e-11
gi|34932414 non-POU domain containing, octamer-binding isoform 1...    69   2e-11
gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2, ...    68   3e-11
gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo...    64   7e-10
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         61   3e-09
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]                      61   4e-09
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]                      61   4e-09
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]                      61   4e-09
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]                      61   4e-09
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]                      61   4e-09
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila...    60   6e-09
gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]        59   1e-08
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                59   1e-08
gi|209862867 poly-U binding splicing factor 60KDa isoform c [Hom...    59   1e-08
gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo...    59   1e-08
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]               59   1e-08
gi|38201714 ELAV-like 1 [Homo sapiens]                                 58   4e-08
gi|119829187 alpha 1 type XVII collagen [Homo sapiens]                 57   6e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     57   6e-08
gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo s...    57   8e-08
gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo sa...    57   8e-08
gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo s...    57   8e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    57   8e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre...    57   8e-08
gi|49472822 eukaryotic translation initiation factor 3, subunit ...    56   1e-07

>gi|123173757 RAVER1 [Homo sapiens]
          Length = 756

 Score = 1538 bits (3982), Expect = 0.0
 Identities = 756/756 (100%), Positives = 756/756 (100%)

Query: 1   MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEE 60
           MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEE
Sbjct: 1   MPLRPGSLVPEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEE 60

Query: 61  IRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNG 120
           IRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNG
Sbjct: 61  IRKRLEHTERQFRNRRKILIRGLPGDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNG 120

Query: 121 EQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           EQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFL
Sbjct: 121 EQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRCL 240
           VYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRCL
Sbjct: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSRCL 240

Query: 241 CVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQAD 300
           CVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQAD
Sbjct: 241 CVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQAD 300

Query: 301 GLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASL 360
           GLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASL
Sbjct: 301 GLSLGGSHLRVSFCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASL 360

Query: 361 QLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGA 420
           QLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGA
Sbjct: 361 QLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGA 420

Query: 421 LQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLT 480
           LQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLT
Sbjct: 421 LQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLT 480

Query: 481 PPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAG 540
           PPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAG
Sbjct: 481 PPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAG 540

Query: 541 KEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDS 600
           KEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDS
Sbjct: 541 KEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDS 600

Query: 601 YSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGS 660
           YSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGS
Sbjct: 601 YSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGS 660

Query: 661 PTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAH 720
           PTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAH
Sbjct: 661 PTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAH 720

Query: 721 LLPSPEPSPEGSYVGQHSQGLGGHYADSYLKRKRIF 756
           LLPSPEPSPEGSYVGQHSQGLGGHYADSYLKRKRIF
Sbjct: 721 LLPSPEPSPEGSYVGQHSQGLGGHYADSYLKRKRIF 756


>gi|51948366 ribonucleoprotein, PTB-binding 2 [Homo sapiens]
          Length = 678

 Score =  423 bits (1088), Expect = e-118
 Identities = 255/573 (44%), Positives = 325/573 (56%), Gaps = 63/573 (10%)

Query: 30  LSPKSGAEVEAGDA-AERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDVT 88
           L P  G   +   A A   AP+     L PEE+  RL+  +R+  NRRKIL++ LP D  
Sbjct: 22  LGPGPGLRGQGPSAEAHEGAPDPMPAALHPEEVAARLQRMQRELSNRRKILVKNLPQDSN 81

Query: 89  NQEVHDLLSDYELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQPTD 148
            QEVHDLL DY+LKYC+VD+ K TAFVTLLNGEQA+ AI  FHQ   R ++L VQLQPTD
Sbjct: 82  CQEVHDLLKDYDLKYCYVDRNKRTAFVTLLNGEQAQNAIQMFHQYSFRGKDLIVQLQPTD 141

Query: 149 ALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKS 208
           ALLC+ N+P S T ++FEELVR +G++ERCFLVYSE TG SKGYGF EYMKKD AA+A+ 
Sbjct: 142 ALLCITNVPISFTSEEFEELVRAYGNIERCFLVYSEVTGHSKGYGFVEYMKKDFAAKARL 201

Query: 209 DLLGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFC 268
           +LLG+ LG   L+  W D   L   L+HS+CLC+D+LP  + D + L +  S+VH P FC
Sbjct: 202 ELLGRQLGASALFAQWMDVNLLASELIHSKCLCIDKLPSDYRDSEELLQIFSSVHKPVFC 261

Query: 269 QLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALI 328
           QLA  +   + GFAV+EY TAE AEE QQ ADG+++ GS ++VSFCAPG PGRS LAALI
Sbjct: 262 QLAQDEGSYVGGFAVVEYSTAEQAEEVQQAADGMTIKGSKVQVSFCAPGAPGRSTLAALI 321

Query: 329 AAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLL 388
           AAQ    +  KGLLPEPN +Q++ +L   A LQ+LL P L G A  K  +LG P ++P L
Sbjct: 322 AAQRVMHSNQKGLLPEPNPVQIMKSLNNPAMLQVLLQPQLCGRA-VKPAVLGTPHSLPHL 380

Query: 389 NGPALSTALLQLALQTQG-------------------QKKPGILGDSPLGALQP--GAQP 427
             P++S A L L    Q                      KPG+LG+ P   LQ   G   
Sbjct: 381 MNPSISPAFLHLNKAHQNLSHIPLAQQQLMKFENIHTNNKPGLLGEPPAVVLQTALGIGS 440

Query: 428 ANPLLGEL--------------------PAGGGLPPELP---------PRRGKPPPLLPS 458
             PL  EL                     AG G+ P  P         P         P+
Sbjct: 441 VLPLKKELGHHHGEAHKTSSLIPTQTTITAGMGMLPFFPNQHIAGQAGPGHSNTQEKQPA 500

Query: 459 VLGPAGGDREALGLGPPAAQLTPPPAPVGL-------RGSGLRGLQKDSGPLPTPPGVSL 511
            +G A G+        P  Q  P  A   L       + S  +G +  SG   +    SL
Sbjct: 501 TVGMAEGNFSG---SQPYLQSFPNLAAGSLLVGHHKQQQSQPKGTEISSG-AASKNQTSL 556

Query: 512 LGEPPKDYRIPLNPYLNLHSLLPASNLAGKEAR 544
           LGEPPK+ R+  NPYLNL S+LP+  L+   ++
Sbjct: 557 LGEPPKEIRLSKNPYLNLASVLPSVCLSSPASK 589



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 30/100 (30%), Positives = 42/100 (42%), Gaps = 17/100 (17%)

Query: 658 SGSPTSYFTSGLQAGLKQSHLSKAIG-SSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKR 716
           +G  +S   +  Q    Q  L K I  S P G    +  L     G S+L+  P GG   
Sbjct: 595 TGIASSILDAISQGSESQHALEKCIAYSPPFGDYAQVSSLRNEKRGSSYLISAPEGGSVE 654

Query: 717 SFAHLLPSPEPSPEGSYVGQHSQGLGGHYADSYLKRKRIF 756
                            V QHSQG G +Y ++YLK+KR++
Sbjct: 655 C----------------VDQHSQGTGAYYMETYLKKKRVY 678


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 71.2 bits (173), Expect = 3e-12
 Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 2/139 (1%)

Query: 69  ERQFRNRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAI 127
           E+ +  R ++ +  LP D+T  E   L + Y E    F++K KG  F+ L +   AE A 
Sbjct: 290 EKTYTQRCRLFVGNLPADITEDEFKRLFAKYGEPGEVFINKGKGFGFIKLESRALAEIAK 349

Query: 128 NAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTG 187
                + +R R+L V+     A L V NL P ++ +  EE    FG +ER  ++  +R G
Sbjct: 350 AELDDTPMRGRQLRVRFATHAAALSVRNLSPYVSNELLEEAFSQFGPIERAVVIVDDR-G 408

Query: 188 QSKGYGFAEYMKKDSAARA 206
           +S G G  E+  K +A +A
Sbjct: 409 RSTGKGIVEFASKPAARKA 427



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 67/243 (27%), Positives = 75/243 (30%), Gaps = 72/243 (29%)

Query: 405 QGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAG 464
           Q Q+ P    DS    +  G  PA  +    PA    PP  PP  G PP   P   GP  
Sbjct: 95  QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGP---GPTP 151

Query: 465 GDREALGLGPPAAQLTPPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLN 524
               A+   PP A   PPP P              SG   TPP     G PP        
Sbjct: 152 TPPPAVTSAPPGA---PPPTP------------PSSGVPTTPPQAG--GPPPPP------ 188

Query: 525 PYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLS 584
                 + +P      K+  G GG      P  G     P PGGG               
Sbjct: 189 ------AAVPGPGPGPKQGPGPGG------PKGGKMPGGPKPGGG--------------- 221

Query: 585 PLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPREPALGPHGP---SRHKMSPPPSGFG 641
                     PGLS       P    P R    PR      H P    +H   PPP G G
Sbjct: 222 ----------PGLSTPGGHPKP----PHRGGGEPRGGR--QHHPPYHQQHHQGPPPGGPG 265

Query: 642 ERS 644
            RS
Sbjct: 266 GRS 268



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 60/219 (27%), Positives = 79/219 (36%), Gaps = 62/219 (28%)

Query: 380 GAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSP-----LGALQPGAQPANPLLGE 434
           G  PA  + + P  S++       T G       G +P     + +  PGA P  P    
Sbjct: 114 GPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTP---- 169

Query: 435 LPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLR 494
            P+ G   P  PP+ G PPP   +V GP  G ++              P P G +G  + 
Sbjct: 170 -PSSG--VPTTPPQAGGPPPPPAAVPGPGPGPKQG-------------PGPGGPKGGKMP 213

Query: 495 GLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRR 554
           G  K  G     PG+S  G  PK                   +  G E RG    GR   
Sbjct: 214 GGPKPGG----GPGLSTPGGHPK-----------------PPHRGGGEPRG----GRQHH 248

Query: 555 PA------EGPPTNPPAPGGGS----SSSKAFQLKSRLL 583
           P       +GPP  P  PGG S    S S+ F+    LL
Sbjct: 249 PPYHQQHHQGPP--PGGPGGRSEEKISDSEGFKANLSLL 285



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 35/145 (24%), Positives = 60/145 (41%), Gaps = 16/145 (11%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V NLP  +T+ +F+ L   +G     F+       + KG+GF +   +  A  AK++L
Sbjct: 299 LFVGNLPADITEDEFKRLFAKYGEPGEVFI------NKGKGFGFIKLESRALAEIAKAEL 352

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
              P+  R L V +           H+  L V  L P  ++ + L  A S         +
Sbjct: 353 DDTPMRGRQLRVRFA---------THAAALSVRNLSPYVSN-ELLEEAFSQFGPIERAVV 402

Query: 271 ACGQDGQLKGFAVLEYETAEMAEEA 295
                G+  G  ++E+ +   A +A
Sbjct: 403 IVDDRGRSTGKGIVEFASKPAARKA 427


>gi|109240550 paraspeckle protein 1 [Homo sapiens]
          Length = 523

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 52/185 (28%), Positives = 86/185 (46%), Gaps = 10/185 (5%)

Query: 31  SPKSGAEVEAGDAAERRAPEEELPPLD-PEE-------IRKRLEHTERQFRNRRKILIRG 82
           S  + A   A   A   AP    PP D P+E       I+  L+  E+ +  R ++ +  
Sbjct: 29  SEPAAAAAMALALAGEPAPPAPAPPEDHPDEEMGFTIDIKSFLKPGEKTYTQRCRLFVGN 88

Query: 83  LPGDVTNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELS 141
           LP D+T ++   L   Y E    F+++ +G  F+ L +   AE A      + L+ R L 
Sbjct: 89  LPTDITEEDFKRLFERYGEPSEVFINRDRGFGFIRLESRTLAEIAKAELDGTILKSRPLR 148

Query: 142 VQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKD 201
           ++     A L V NL P ++ +  E+    FG +E+  +V  +R G++ G GF E+  K 
Sbjct: 149 IRFATHGAALTVKNLSPVVSNELLEQAFSQFGPVEKAVVVVDDR-GRATGKGFVEFAAKP 207

Query: 202 SAARA 206
            A +A
Sbjct: 208 PARKA 212



 Score = 37.4 bits (85), Expect = 0.052
 Identities = 37/155 (23%), Positives = 62/155 (40%), Gaps = 17/155 (10%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V NLP  +T++ F+ L   +G     F+       + +G+GF     +  A  AK++L
Sbjct: 84  LFVGNLPTDITEEDFKRLFERYGEPSEVFI------NRDRGFGFIRLESRTLAEIAKAEL 137

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  R L + +           H   L V  L P  ++ + L +A S         +
Sbjct: 138 DGTILKSRPLRIRFA---------THGAALTVKNLSPVVSN-ELLEQAFSQFGPVEKAVV 187

Query: 271 ACGQDGQLKGFAVLEYETAEMAEEAQQQ-ADGLSL 304
                G+  G   +E+     A +A ++  DG  L
Sbjct: 188 VVDDRGRATGKGFVEFAAKPPARKALERCGDGAFL 222


>gi|224028246 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 28  PPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDV 87
           PP  P +G +  +         + E   +D +  RK  E T   F  R ++ +  LP D+
Sbjct: 38  PPPIPANGQQASS---------QNEGLTIDLKNFRKPGEKT---FTQRSRLFVGNLPPDI 85

Query: 88  TNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQP 146
           T +E+  L   Y +    F+ K KG  F+ L     AE A        LR ++L V+   
Sbjct: 86  TEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFAC 145

Query: 147 TDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARA 206
             A L V NLP  ++ +  EE    FG +ER  ++  +R G+  G G  E+  K +A +A
Sbjct: 146 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDR-GRPSGKGIVEFSGKPAARKA 204



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 46/198 (23%), Positives = 75/198 (37%), Gaps = 20/198 (10%)

Query: 119 NGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERC 178
           NG+QA +            R+   +     + L V NLPP +T+++  +L   +G     
Sbjct: 44  NGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEV 103

Query: 179 FLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSR 238
           F+       + KG+GF     +  A  AK +L   PL  + L V +           HS 
Sbjct: 104 FI------HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA---------CHSA 148

Query: 239 CLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQ 298
            L V  LP   ++ + L  A S         +     G+  G  ++E+     A +A  +
Sbjct: 149 SLTVRNLPQYVSN-ELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDR 207

Query: 299 ADGLSLGGSHLRVSFCAP 316
                  GS L  +F  P
Sbjct: 208 CS----EGSFLLTTFPRP 221


>gi|224028244 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 28  PPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDV 87
           PP  P +G +  +         + E   +D +  RK  E T   F  R ++ +  LP D+
Sbjct: 38  PPPIPANGQQASS---------QNEGLTIDLKNFRKPGEKT---FTQRSRLFVGNLPPDI 85

Query: 88  TNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQP 146
           T +E+  L   Y +    F+ K KG  F+ L     AE A        LR ++L V+   
Sbjct: 86  TEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFAC 145

Query: 147 TDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARA 206
             A L V NLP  ++ +  EE    FG +ER  ++  +R G+  G G  E+  K +A +A
Sbjct: 146 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDR-GRPSGKGIVEFSGKPAARKA 204



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 46/198 (23%), Positives = 75/198 (37%), Gaps = 20/198 (10%)

Query: 119 NGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERC 178
           NG+QA +            R+   +     + L V NLPP +T+++  +L   +G     
Sbjct: 44  NGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEV 103

Query: 179 FLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSR 238
           F+       + KG+GF     +  A  AK +L   PL  + L V +           HS 
Sbjct: 104 FI------HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA---------CHSA 148

Query: 239 CLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQ 298
            L V  LP   ++ + L  A S         +     G+  G  ++E+     A +A  +
Sbjct: 149 SLTVRNLPQYVSN-ELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDR 207

Query: 299 ADGLSLGGSHLRVSFCAP 316
                  GS L  +F  P
Sbjct: 208 CS----EGSFLLTTFPRP 221


>gi|34932414 non-POU domain containing, octamer-binding isoform 1
           [Homo sapiens]
          Length = 471

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 14/180 (7%)

Query: 28  PPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTERQFRNRRKILIRGLPGDV 87
           PP  P +G +  +         + E   +D +  RK  E T   F  R ++ +  LP D+
Sbjct: 38  PPPIPANGQQASS---------QNEGLTIDLKNFRKPGEKT---FTQRSRLFVGNLPPDI 85

Query: 88  TNQEVHDLLSDY-ELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQLQP 146
           T +E+  L   Y +    F+ K KG  F+ L     AE A        LR ++L V+   
Sbjct: 86  TEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFAC 145

Query: 147 TDALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARA 206
             A L V NLP  ++ +  EE    FG +ER  ++  +R G+  G G  E+  K +A +A
Sbjct: 146 HSASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVDDR-GRPSGKGIVEFSGKPAARKA 204



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 46/198 (23%), Positives = 75/198 (37%), Gaps = 20/198 (10%)

Query: 119 NGEQAEAAINAFHQSRLRERELSVQLQPTDALLCVANLPPSLTQQQFEELVRPFGSLERC 178
           NG+QA +            R+   +     + L V NLPP +T+++  +L   +G     
Sbjct: 44  NGQQASSQNEGLTIDLKNFRKPGEKTFTQRSRLFVGNLPPDITEEEMRKLFEKYGKAGEV 103

Query: 179 FLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYVHWTDAGQLTPALLHSR 238
           F+       + KG+GF     +  A  AK +L   PL  + L V +           HS 
Sbjct: 104 FI------HKDKGFGFIRLETRTLAEIAKVELDNMPLRGKQLRVRFA---------CHSA 148

Query: 239 CLCVDRLPPGFNDVDALCRALSAVHSPTFCQLACGQDGQLKGFAVLEYETAEMAEEAQQQ 298
            L V  LP   ++ + L  A S         +     G+  G  ++E+     A +A  +
Sbjct: 149 SLTVRNLPQYVSN-ELLEEAFSVFGQVERAVVIVDDRGRPSGKGIVEFSGKPAARKALDR 207

Query: 299 ADGLSLGGSHLRVSFCAP 316
                  GS L  +F  P
Sbjct: 208 CS----EGSFLLTTFPRP 221


>gi|14149675 cleavage stimulation factor, 3' pre-RNA, subunit 2,
           64kDa, tau variant [Homo sapiens]
          Length = 616

 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 130/545 (23%), Positives = 201/545 (36%), Gaps = 111/545 (20%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V N+P   T++Q +++    GS+    LVY   TG+ KGYGF EY  +++A  A  +L G
Sbjct: 20  VGNIPYEATEEQLKDIFSEVGSVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNG 79

Query: 213 KPLGPRTLYV-------HWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSP 265
           +    R L V       +  +   L PA         D + P  +  +++ RA++++   
Sbjct: 80  REFSGRALRVDNAASEKNKEELKSLGPAAPIIDSPYGDPIDPE-DAPESITRAVASLPPE 138

Query: 266 TFCQL-----ACGQDGQLKGFAV------LEYETAEMAEEAQQQADGLSLGGSHLRVSFC 314
              +L      C Q+   +   +      L Y   +     +     ++L   H ++   
Sbjct: 139 QMFELMKQMKLCVQNSHQEARNMLLQNPQLAYALLQAQVVMRIMDPEIALKILHRKI-HV 197

Query: 315 APGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGG 374
            P  PG+S     ++        G GL P PN+  LLN   P A     L          
Sbjct: 198 TPLIPGKSQ---SVSVSGPGPGPGPGLCPGPNV--LLNQQNPPAPQPQHL---------A 243

Query: 375 KQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGE 434
           ++ +   PP             L+Q  +Q       GI    P+ A  PGA P     G 
Sbjct: 244 RRPVKDIPP-------------LMQTPIQ------GGIPAPGPIPAAVPGAGP-----GS 279

Query: 435 LPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLR 494
           L  GG + P+L    G P       +GP   +R  + +  P A +  P  PV   G   R
Sbjct: 280 LTPGGAMQPQL----GMPG------VGPVPLERGQVQMSDPRAPI--PRGPVTPGGLPPR 327

Query: 495 GLQKDSGPLPTPPG----VSLLGE-PPKDYRIPLNPYLNLHSLLPASNLAGKEARG---- 545
           GL  D+   P  P     +S+ GE  P+ Y  P       H   P  + +G + RG    
Sbjct: 328 GLLGDA---PNDPRGGTLLSVTGEVEPRGYLGP------PHQGPPMHHASGHDTRGPSSH 378

Query: 546 --WGGAGRSRRPAEGPPTNP-------PAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPG 596
              GG     R   G P  P       P  G G   S+A + ++ + + +   R+    G
Sbjct: 379 EMRGGPLGDPRLLIGEPRGPMIDQRGLPMDGRGGRDSRAMETRA-METEVLETRVMERRG 437

Query: 597 LSDSYSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHF 656
           +           M  R +       A G          P PS  G  + G  G GP++  
Sbjct: 438 ME-------TCAMETRGM------EARGMDARGLEMRGPVPSSRGPMTGGIQGPGPINIG 484

Query: 657 YSGSP 661
             G P
Sbjct: 485 AGGPP 489


>gi|17298690 poly-U binding splicing factor 60KDa isoform b [Homo
           sapiens]
          Length = 542

 Score = 63.5 bits (153), Expect = 7e-10
 Identities = 75/318 (23%), Positives = 129/318 (40%), Gaps = 31/318 (9%)

Query: 129 AFHQSRLRERELSVQLQPTDALLC---VANLPPSLTQQQFEELVRPFGSLERCFLVYSER 185
           A  Q +L   +++ Q Q   A++C   V ++   L +    +   PFG ++   + +   
Sbjct: 89  AHQQQQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSV 148

Query: 186 TGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYV-HWTDAGQLTPAL--LHSRCLCV 242
           T + KG+ F EY   ++A  A   +    LG R + V   ++ GQ  P +  L       
Sbjct: 149 TMKHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAF 208

Query: 243 DRLPPGF-------NDVDALCRALSAVHSPTFCQLACGQD-GQLKGFAVLEYETAEMAEE 294
           +R+           +D+ ++  A   + S   C LA     G+ KG+  +EYE A+ +++
Sbjct: 209 NRIYVASVHQDLSDDDIKSVFEAFGKIKS---CTLARDPTTGKHKGYGFIEYEKAQSSQD 265

Query: 295 AQQQADGLSLGGSHLRVS--------FCAPGPP-GRSMLAALIAAQATALNRGKGLLPEP 345
           A    +   LGG +LRV            P  P G    AA+ AA ATA    +  +   
Sbjct: 266 AVSSMNLFDLGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGA 325

Query: 346 NILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQ 405
            +L  L   G  +    L  PL     G     + A  A  ++ G   +   + + + + 
Sbjct: 326 AVLGTLGTPGLVSPALTLAQPL-----GTLPQAVMAAQAPGVITGVTPARPPIPVTIPSV 380

Query: 406 GQKKPGILGDSPLGALQP 423
           G   P +     LG L+P
Sbjct: 381 GVVNPILASPPTLGLLEP 398



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 61/250 (24%), Positives = 101/250 (40%), Gaps = 40/250 (16%)

Query: 10  PEGAGFPKMAADVSVTHRPPLSPKSGAEVEAGDAAERRAPEEELPPLDPEEIRKRLEHTE 69
           P+G    KM    S   +  L P +  + EA   A++ A E+ +  +    +++ + H +
Sbjct: 36  PQGTDSIKMENGQSTAAKLGLPPLTPEQQEALQKAKKYAMEQSIKSV---LVKQTIAHQQ 92

Query: 70  RQFRNRRK---------ILIRGLPGDVTNQEVHDLL----------SDYELKYCFVD-KY 109
           +Q  N +          I+ R   G +  +   D +             ++ +  V  K+
Sbjct: 93  QQLTNLQMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKH 152

Query: 110 KGTAFVTLLNGEQAEAAINAFHQSRLRERELSV-------QLQPT-DAL---------LC 152
           KG AFV     E A+ A+   +   L  R + V       Q QP  D L         + 
Sbjct: 153 KGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIY 212

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           VA++   L+    + +   FG ++ C L     TG+ KGYGF EY K  S+  A S +  
Sbjct: 213 VASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNL 272

Query: 213 KPLGPRTLYV 222
             LG + L V
Sbjct: 273 FDLGGQYLRV 282


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 107/398 (26%), Positives = 133/398 (33%), Gaps = 111/398 (27%)

Query: 356 PSAS-LQLLLNPLLHG-SAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGIL 413
           P+AS   ++ +P+L   S G   G   A P  PL  G A      +  L   G   PG+L
Sbjct: 479 PAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML 538

Query: 414 GDSPLGALQPGAQPANPLL-----GELPAGGGLPPE---LPPRRGKPPPLLPS------- 458
           G  PL  L  G  P +PLL     G L  GGG PP    LPP  G  PPL P        
Sbjct: 539 GALPL-PLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLAPGEPEGPSL 597

Query: 459 --------------------------------VLGPAGGDRE--ALGLGPPAAQ------ 478
                                            LGP  GD E  A G G P+ +      
Sbjct: 598 LVASLLPPPPSDLLPPPSAPPSNLLASFLPLLALGPTAGDGEGSAEGAGGPSGEPFSGLG 657

Query: 479 ---------LTPPPAPVGLRGSGLRG-LQKDSGPLPTP---------------------P 507
                    L+ PP  + L  + L   L   SG  P P                     P
Sbjct: 658 DLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTSSVTTATTDP 717

Query: 508 GVSLLGEPPKDYRIP---LNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPP 564
           G S LG+ P +   P   L+P L    L   S+L         GA  S     GP  +  
Sbjct: 718 GASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSP-----GALPSLLQPPGPLLSGQ 772

Query: 565 -----APGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPR 619
                 PGGG+    + +  S L   L S ++PPE   +       P +     L   P 
Sbjct: 773 LGLQLLPGGGAPPPLS-EASSPLACLLQSLQIPPEQPEAPC----LPPESPASALEPEPA 827

Query: 620 EPALGPHGPSRHKMSPPP----SGFGERSSGGSGGGPL 653
            P L    P      PP     +G G    G  GGG L
Sbjct: 828 RPPLSALAPPHGSPDPPVPELLTGRGSGKRGRRGGGGL 865



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 97/376 (25%), Positives = 132/376 (35%), Gaps = 86/376 (22%)

Query: 316 PGPPGRSMLAALIAAQATALNRGKGLLPE-------PNILQLLNNLGPSASLQLLLNPLL 368
           P PP  ++      AQA + +    L P        P + +LL   GP    +       
Sbjct: 334 PLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRR------- 386

Query: 369 HGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKP----GILGDS----PLGA 420
             S       +  P ++P  + P L + L  L L T G         +LG      P   
Sbjct: 387 --SRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPT 444

Query: 421 LQPGA--QPANPLLGELPAG-----GGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLG 473
           L  G+  QP +P+   LP         +P    P      P++PS +  +  +   +G G
Sbjct: 445 LSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAASKAPVVPSPVLQSPSEGLGMGAG 504

Query: 474 PPA-------AQLTPPPAP---VGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPL 523
           P          +  P P+P   + L G+G  G+    G LP P     LG+PP       
Sbjct: 505 PACPLPPLAGGEAFPFPSPEQGLALSGAGFPGML---GALPLPLS---LGQPPP------ 552

Query: 524 NPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLL 583
           +P LN HSL     L G      GG      P   PP  P  P           L + LL
Sbjct: 553 SPLLN-HSLFGV--LTG------GGGQPPPEPLLPPPGGPGPPLAPGEPEGPSLLVASLL 603

Query: 584 SPLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGER 643
            P  S  LPP            PS      L S     ALG           P +G GE 
Sbjct: 604 PPPPSDLLPP------------PSAPPSNLLASFLPLLALG-----------PTAGDGEG 640

Query: 644 SSGGSGGGPLSHFYSG 659
           S+ G+ GGP    +SG
Sbjct: 641 SAEGA-GGPSGEPFSG 655



 Score = 46.6 bits (109), Expect = 9e-05
 Identities = 57/191 (29%), Positives = 69/191 (36%), Gaps = 34/191 (17%)

Query: 316 PGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSA-GG 374
           PGPP  S+  A     A++L +       P                 LL+PLL  S  G 
Sbjct: 703 PGPPTSSVTTATTDPGASSLGKAPSNSGRP---------------PQLLSPLLGASLLGD 747

Query: 375 KQGLLGAPPAMPLL---NGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPL 431
              L  +P A+P L    GP LS  L    L   G   P     SPL  L    Q    +
Sbjct: 748 LSSLTSSPGALPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQ----I 803

Query: 432 LGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPP-PAPVGLRG 490
             E P    LPPE P    +P P  P +            L PP     PP P  +  RG
Sbjct: 804 PPEQPEAPCLPPESPASALEPEPARPPLSA----------LAPPHGSPDPPVPELLTGRG 853

Query: 491 SGLRGLQKDSG 501
           SG RG +   G
Sbjct: 854 SGKRGRRGGGG 864



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 83/278 (29%), Positives = 103/278 (37%), Gaps = 45/278 (16%)

Query: 315 APGPP-GRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLL---HG 370
           APG P G S+L A +     +      LLP P+     +NL  S    L L P      G
Sbjct: 588 APGEPEGPSLLVASLLPPPPS-----DLLPPPSAPP--SNLLASFLPLLALGPTAGDGEG 640

Query: 371 SAGGKQGLLGAP-----PAMPLLNGP--------ALSTALLQLALQTQGQKKPGILGDSP 417
           SA G  G  G P        PLL  P        AL++ALL   L       P       
Sbjct: 641 SAEGAGGPSGEPFSGLGDLSPLLFPPLSAPPTLIALNSALLAATLDPPSGTPPQ---PCV 697

Query: 418 LGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPA-GGDREALGLGPPA 476
           L A QPG   ++        G     + P   G+PP LL  +LG +  GD  +L   P A
Sbjct: 698 LSAPQPGPPTSSVTTATTDPGASSLGKAPSNSGRPPQLLSPLLGASLLGDLSSLTSSPGA 757

Query: 477 -AQLTPPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLG-------EPPKDYRIPLNPYLN 528
              L  PP P+     GL+ L     P P     S L         PP+    P  P  +
Sbjct: 758 LPSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPEAPCLPPES 817

Query: 529 LHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAP 566
                PAS L  + AR    A     P  G P +PP P
Sbjct: 818 -----PASALEPEPARPPLSA---LAPPHGSP-DPPVP 846



 Score = 34.7 bits (78), Expect = 0.34
 Identities = 82/337 (24%), Positives = 110/337 (32%), Gaps = 39/337 (11%)

Query: 330 AQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPL----LHGSAGGKQGLLGAPPAM 385
           A  T    G G   E ++ +L N+   + ++  L   +     H S G      GA P M
Sbjct: 80  APVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGE-----GASPQM 134

Query: 386 --PLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANP-------LLGELP 436
              +  GP  +    ++   T     PG L   P    Q     A P       L   +P
Sbjct: 135 FHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVP 194

Query: 437 AGGGLPPELPPRRGKPPPLLP-----SVLGPAGGDREALGLGPPAAQLTPPPAPVGLRG- 490
           +GG   P   PR   P P  P     S+  P+     AL      + L  PPAP      
Sbjct: 195 SGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSP 254

Query: 491 ---SGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWG 547
                L        P P PP  +L   P    + P++    +H  L    L G       
Sbjct: 255 PSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS-ATMHLPLVLGPLGGAPTVEGP 313

Query: 548 GAG--------RSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSD 599
           GA          +   A+ PP  PP+   G          S   S   S R P  P  + 
Sbjct: 314 GAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSASHSSSLRPSQRRPRRPP-TV 372

Query: 600 SYSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPP 636
               +      PRR  S PR PA  P   S  + S P
Sbjct: 373 FRLLEGRGPQTPRR--SRPRAPAPVPQPFSLPEPSQP 407


>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
          Length = 380

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E   L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 44  SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 104 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 163

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 5/188 (2%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++F  L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 48  LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  +T+ V +    + + A +    L V  LP      + L +  S        ++
Sbjct: 108 NGLRLQTKTIKVSY---ARPSSASIRDANLYVSGLPKTMTQKE-LEQLFSQYGRIITSRI 163

Query: 271 ACGQ-DGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIA 329
              Q  G  +G   + ++    AEEA +  +G    G+   ++      P +    AL++
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 223

Query: 330 AQATALNR 337
               + NR
Sbjct: 224 QLYQSPNR 231



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    +L  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 301 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 360

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 361 YRLGDRVLQV 370


>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
          Length = 369

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E   L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 47  SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 106

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 107 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 166

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 167 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 203



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 5/188 (2%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++F  L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 51  LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 110

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  +T+ V +    + + A +    L V  LP      + L +  S        ++
Sbjct: 111 NGLRLQTKTIKVSY---ARPSSASIRDANLYVSGLPKTMTQKE-LEQLFSQYGRIITSRI 166

Query: 271 ACGQ-DGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIA 329
              Q  G  +G   + ++    AEEA +  +G    G+   ++      P +    AL++
Sbjct: 167 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 226

Query: 330 AQATALNR 337
               + NR
Sbjct: 227 QLYQSPNR 234



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    +L  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 290 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 349

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 350 YRLGDRVLQV 359


>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
          Length = 366

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E   L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 44  SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 104 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 163

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 5/188 (2%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++F  L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 48  LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  +T+ V +    + + A +    L V  LP      + L +  S        ++
Sbjct: 108 NGLRLQTKTIKVSY---ARPSSASIRDANLYVSGLPKTMTQKE-LEQLFSQYGRIITSRI 163

Query: 271 ACGQ-DGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIA 329
              Q  G  +G   + ++    AEEA +  +G    G+   ++      P +    AL++
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 223

Query: 330 AQATALNR 337
               + NR
Sbjct: 224 QLYQSPNR 231



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    +L  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 287 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 346

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 347 YRLGDRVLQV 356


>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
          Length = 383

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E   L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 61  SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 120

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 121 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 180

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 181 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 217



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 5/188 (2%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++F  L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 65  LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 124

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  +T+ V +    + + A +    L V  LP      + L +  S        ++
Sbjct: 125 NGLRLQTKTIKVSY---ARPSSASIRDANLYVSGLPKTMTQKE-LEQLFSQYGRIITSRI 180

Query: 271 ACGQ-DGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIA 329
              Q  G  +G   + ++    AEEA +  +G    G+   ++      P +    AL++
Sbjct: 181 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 240

Query: 330 AQATALNR 337
               + NR
Sbjct: 241 QLYQSPNR 248



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    +L  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 304 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 363

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 364 YRLGDRVLQV 373


>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
          Length = 366

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 45/157 (28%), Positives = 80/157 (50%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E   L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 44  SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 104 INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 163

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200



 Score = 55.5 bits (132), Expect = 2e-07
 Identities = 50/188 (26%), Positives = 82/188 (43%), Gaps = 5/188 (2%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++F  L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 48  LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQL 270
            G  L  +T+ V +    + + A +    L V  LP      + L +  S        ++
Sbjct: 108 NGLRLQTKTIKVSY---ARPSSASIRDANLYVSGLPKTMTQKE-LEQLFSQYGRIITSRI 163

Query: 271 ACGQ-DGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALIA 329
              Q  G  +G   + ++    AEEA +  +G    G+   ++      P +    AL++
Sbjct: 164 LVDQVTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSGATEPITVKFANNPSQKSSQALLS 223

Query: 330 AQATALNR 337
               + NR
Sbjct: 224 QLYQSPNR 231



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 24/70 (34%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    +L  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 287 VYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 346

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 347 YRLGDRVLQV 356


>gi|115511032 ELAV (embryonic lethal, abnormal vision,
           Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
          Length = 359

 Score = 60.5 bits (145), Expect = 6e-09
 Identities = 45/157 (28%), Positives = 81/157 (51%), Gaps = 14/157 (8%)

Query: 74  NRRKILIRGLPGDVTNQEVHDLLSDY-ELKYCFVDKYK------GTAFVTLLNGEQAEAA 126
           ++  +++  LP ++T +E+  L     E++ C + + K      G  FV  ++ + AE A
Sbjct: 37  SKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 96

Query: 127 INAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFL 180
           IN  +  RL+ + + V   +P+     DA L V+ LP ++TQ++ E+L   +G +    +
Sbjct: 97  INTLNGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRI 156

Query: 181 VYSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
           +  + TG S+G GF  + K+  A  A   L G KP G
Sbjct: 157 LVDQVTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPG 193



 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 28/74 (37%), Positives = 41/74 (55%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ++ + L    G +E C LV  + TGQS GYGF  Y+    A +A + L
Sbjct: 41  LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100

Query: 211 LGKPLGPRTLYVHW 224
            G  L  +T+ V +
Sbjct: 101 NGLRLQTKTIKVSY 114



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 23/70 (32%), Positives = 33/70 (47%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V NL P   +    ++  PFG++    ++    T + KG+GF      D AA A + L G
Sbjct: 280 VYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASLNG 339

Query: 213 KPLGPRTLYV 222
             LG R L V
Sbjct: 340 YRLGDRVLQV 349


>gi|4557493 cleavage stimulation factor subunit 2 [Homo sapiens]
          Length = 577

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 127/565 (22%), Positives = 198/565 (35%), Gaps = 79/565 (13%)

Query: 153 VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLG 212
           V N+P   T++Q +++    G +    LVY   TG+ KGYGF EY  +++A  A  +L G
Sbjct: 20  VGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNG 79

Query: 213 KPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGFNDVDALCRALSAVHSPTFCQLAC 272
           +    R L V    A +     L S       +   + +       +S   +P     A 
Sbjct: 80  REFSGRALRVD-NAASEKNKEELKSLGTGAPVIESPYGE------TISPEDAPESISKAV 132

Query: 273 GQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSM---LAALIA 329
                 + F +++ +     + + Q+A  + L    L  +        R +   +A  I 
Sbjct: 133 ASLPPEQMFELMK-QMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMRIVDPEIALKIL 191

Query: 330 AQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLN 389
            + T +       P+P     ++  GP +   + +N   +  A   Q L G    M +  
Sbjct: 192 HRQTNIPTLIAGNPQP-----VHGAGPGSGSNVSMNQ-QNPQAPQAQSLGG----MHVNG 241

Query: 390 GPALSTALLQLALQTQGQKKPGILGDSPLGALQPG----AQPANPLLGELPAGGGLPPEL 445
            P L  A +Q  +   GQ    + G  P G+L PG    AQ   P  G +    G  P  
Sbjct: 242 APPLMQASMQGGVPAPGQMPAAVTGPGP-GSLAPGGGMQAQVGMPGSGPVSMERGQVPMQ 300

Query: 446 PPR----RGKPPPLLPS---VLGPAGGDREALGLGPPAAQLTPPPAPVGLRGSGLRGLQK 498
            PR    RG  P  +P+   +LG A  D      G     +T    P G  G   +G   
Sbjct: 301 DPRAAMQRGSLPANVPTPRGLLGDAPNDPR----GGTLLSVTGEVEPRGYLGPPHQG--- 353

Query: 499 DSGPLPTPPGVSLLGEPPKDYR------------IPLNPYLNLHSLLPASNLAGKEARGW 546
              P+   PG    G PP + R             P  P L+     P     G++ RG 
Sbjct: 354 --PPMHHVPGHESRGPPPHELRGGPLPEPRPLMAEPRGPMLDQRG-PPLDGRGGRDPRGI 410

Query: 547 GGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYP 606
              G   R  E    +  A G  + + +A  +++R +   +      E    ++   D  
Sbjct: 411 DARGMEARAMEARGLD--ARGLEARAMEARAMEARAMEARAMEARAMEVRGMEARGMD-- 466

Query: 607 SDMGPRRLFSHPREPALGPHGPSRHKM-SPPPSGFGERSSGGSGGGPL--------SHFY 657
                       R P  GP GP    M  P P   G     GS   P+        +   
Sbjct: 467 -----------TRGPVPGPRGPIPSGMQGPSPINMGAVVPQGSRQVPVMQGTGMQGASIQ 515

Query: 658 SGSPTSYFTSGLQAGLKQSHLSKAI 682
            GS    F+ G      Q H   A+
Sbjct: 516 GGSQPGGFSPGQNQVTPQDHEKAAL 540


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 121/431 (28%), Positives = 146/431 (33%), Gaps = 110/431 (25%)

Query: 350 LLNNLGPSASLQLLLNPLLHG------SAGGKQGLLGAPPA---MPLLNGPA-------- 392
           +L  L P +SL LLL  L+ G      S GG  G  G  P     P+  GP         
Sbjct: 1   MLGTLTPLSSLLLLLLVLVLGCGPRASSGGGAGGAAGYAPVKYIQPMQKGPVGPPFREGK 60

Query: 393 ---LSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRR 449
              L   L  L +  +G+  PG  G       +PG           P G   PP  P + 
Sbjct: 61  GQYLEMPLPLLPMDLKGE--PGPPG-------KPG-----------PRGPPGPPGFPGKP 100

Query: 450 GKPPPLLPSVLGPAG--GDREALGLGPPAAQ-LTPPPAPVGLRGS-GLRGLQKDSGP--- 502
           G   P L    GPAG  G       GPP       PP   GLRG  G+RG Q   GP   
Sbjct: 101 GMGKPGLHGQPGPAGPPGFSRMGKAGPPGLPGKVGPPGQPGLRGEPGIRGDQGLRGPPGP 160

Query: 503 --LPTPPGVSLLGEP-------PKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSR 553
             LP P G+++ G+P       P  ++    P        P  +   K   G G  G   
Sbjct: 161 PGLPGPSGITIPGKPGAQGVPGPPGFQGEPGPQ---GEPGPPGDRGLKGDNGVGQPGLPG 217

Query: 554 RPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRR 613
            P +G    PP   G +   K                LP  PG  D      P   GPR 
Sbjct: 218 APGQGGAPGPPGLPGPAGLGKP-----------GLDGLPGAPG--DKGESGPPGVPGPR- 263

Query: 614 LFSHPREP-ALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAG 672
                 EP A+GP GP      P   G G   + G  G        G P +    GL   
Sbjct: 264 -----GEPGAVGPKGP------PGVDGVGVPGAAGLPGPQGPSGAKGEPGTRGPPGL--- 309

Query: 673 LKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAHLLPSPEPSPEGS 732
                    IG     +G G+ GL PGP G       P          L    EP  +G 
Sbjct: 310 ---------IGP----TGYGMPGL-PGPKGDRGPAGVP--------GLLGDRGEPGEDGE 347

Query: 733 YVGQHSQGLGG 743
              Q  QGLGG
Sbjct: 348 PGEQGPQGLGG 358



 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 58/192 (30%), Positives = 69/192 (35%), Gaps = 44/192 (22%)

Query: 410 PGILGD--SPLGALQPGAQPANPLLGE--LPAGGGLPPELPPRRGKP----------PPL 455
           PG+LGD   P    +PG Q    L G   LP   GLP     RRG P          PP 
Sbjct: 333 PGLLGDRGEPGEDGEPGEQGPQGLGGPPGLPGSAGLPG----RRGPPGPKGEAGPGGPPG 388

Query: 456 LPSVLGPAGGDREALGLGPPAAQLTP----PPAPVGLRGS-GLRGLQKDSGPLPTPPGVS 510
           +P + G  G    A   G P  +  P    PP P G +G  G  G        P  PGV+
Sbjct: 389 VPGIRGDQGPSGLAGKPGVPGERGLPGAHGPPGPTGPKGEPGFTGR-------PGGPGVA 441

Query: 511 LLGEPPKDYRIPLNPYLNLHSLLPA----------SNLAGKEAR----GWGGAGRSRRPA 556
                  D  +P  P L   S +P             L G +      G  G GR+  P 
Sbjct: 442 GALGQKGDLGLPGQPGLRGPSGIPGLQGPAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPG 501

Query: 557 EGPPTNPPAPGG 568
              PT PP   G
Sbjct: 502 TAGPTGPPGVPG 513



 Score = 38.1 bits (87), Expect = 0.030
 Identities = 60/209 (28%), Positives = 77/209 (36%), Gaps = 41/209 (19%)

Query: 317 GPPGRSMLAALIAAQATALNRGK-GLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAG-- 373
           GPPG    A L   +     +G+ G    P +  +  + GPS    L   P + G  G  
Sbjct: 358 GPPGLPGSAGLPGRRGPPGPKGEAGPGGPPGVPGIRGDQGPSG---LAGKPGVPGERGLP 414

Query: 374 ------GKQGLLGAPPAMPLLNGPALSTALLQLA-LQTQGQKKPGILGDSPLGALQPGAQ 426
                 G  G  G P       GP ++ AL Q   L   GQ  PG+ G S +  LQ    
Sbjct: 415 GAHGPPGPTGPKGEPGFTGRPGGPGVAGALGQKGDLGLPGQ--PGLRGPSGIPGLQG--- 469

Query: 427 PANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTP----- 481
                    PAG   P  LP  +G+P    P   G AG    A   GPP    +P     
Sbjct: 470 ---------PAGPIGPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGP 520

Query: 482 -----PPAPVGLRG----SGLRGLQKDSG 501
                PP P G  G    +G+ GL   +G
Sbjct: 521 PGPPGPPGPPGAPGAFDETGIAGLHLPNG 549


>gi|209862867 poly-U binding splicing factor 60KDa isoform c [Homo
           sapiens]
          Length = 516

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 31/309 (10%)

Query: 138 RELSVQLQPTDALLC---VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGF 194
           + ++ Q Q   A++C   V ++   L +    +   PFG ++   + +   T + KG+ F
Sbjct: 72  QSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAF 131

Query: 195 AEYMKKDSAARAKSDLLGKPLGPRTLYV-HWTDAGQLTPAL--LHSRCLCVDRLPPGF-- 249
            EY   ++A  A   +    LG R + V   ++ GQ  P +  L       +R+      
Sbjct: 132 VEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVH 191

Query: 250 -----NDVDALCRALSAVHSPTFCQLACGQD-GQLKGFAVLEYETAEMAEEAQQQADGLS 303
                +D+ ++  A   + S   C LA     G+ KG+  +EYE A+ +++A    +   
Sbjct: 192 QDLSDDDIKSVFEAFGKIKS---CTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFD 248

Query: 304 LGGSHLRVS--------FCAPGPP-GRSMLAALIAAQATALNRGKGLLPEPNILQLLNNL 354
           LGG +LRV            P  P G    AA+ AA ATA    +  +    +L  L   
Sbjct: 249 LGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTP 308

Query: 355 GPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILG 414
           G  +    L  PL     G     + A  A  ++ G   +   + + + + G   P +  
Sbjct: 309 GLVSPALTLAQPL-----GTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILAS 363

Query: 415 DSPLGALQP 423
              LG L+P
Sbjct: 364 PPTLGLLEP 372



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 17/132 (12%)

Query: 108 KYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSV-------QLQPT-DAL--------- 150
           K+KG AFV     E A+ A+   +   L  R + V       Q QP  D L         
Sbjct: 125 KHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR 184

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           + VA++   L+    + +   FG ++ C L     TG+ KGYGF EY K  S+  A S +
Sbjct: 185 IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSM 244

Query: 211 LGKPLGPRTLYV 222
               LG + L V
Sbjct: 245 NLFDLGGQYLRV 256


>gi|17978512 poly-U binding splicing factor 60KDa isoform a [Homo
           sapiens]
          Length = 559

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 72/309 (23%), Positives = 125/309 (40%), Gaps = 31/309 (10%)

Query: 138 RELSVQLQPTDALLC---VANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGF 194
           + ++ Q Q   A++C   V ++   L +    +   PFG ++   + +   T + KG+ F
Sbjct: 115 QSMAAQRQRALAIMCRVYVGSIYYELGEDTIRQAFAPFGPIKSIDMSWDSVTMKHKGFAF 174

Query: 195 AEYMKKDSAARAKSDLLGKPLGPRTLYV-HWTDAGQLTPAL--LHSRCLCVDRLPPGF-- 249
            EY   ++A  A   +    LG R + V   ++ GQ  P +  L       +R+      
Sbjct: 175 VEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNRIYVASVH 234

Query: 250 -----NDVDALCRALSAVHSPTFCQLACGQD-GQLKGFAVLEYETAEMAEEAQQQADGLS 303
                +D+ ++  A   + S   C LA     G+ KG+  +EYE A+ +++A    +   
Sbjct: 235 QDLSDDDIKSVFEAFGKIKS---CTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSMNLFD 291

Query: 304 LGGSHLRVS--------FCAPGPP-GRSMLAALIAAQATALNRGKGLLPEPNILQLLNNL 354
           LGG +LRV            P  P G    AA+ AA ATA    +  +    +L  L   
Sbjct: 292 LGGQYLRVGKAVTPPMPLLTPATPGGLPPAAAVAAAAATAKITAQEAVAGAAVLGTLGTP 351

Query: 355 GPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILG 414
           G  +    L  PL     G     + A  A  ++ G   +   + + + + G   P +  
Sbjct: 352 GLVSPALTLAQPL-----GTLPQAVMAAQAPGVITGVTPARPPIPVTIPSVGVVNPILAS 406

Query: 415 DSPLGALQP 423
              LG L+P
Sbjct: 407 PPTLGLLEP 415



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 41/132 (31%), Positives = 58/132 (43%), Gaps = 17/132 (12%)

Query: 108 KYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSV-------QLQPT-DAL--------- 150
           K+KG AFV     E A+ A+   +   L  R + V       Q QP  D L         
Sbjct: 168 KHKGFAFVEYEVPEAAQLALEQMNSVMLGGRNIKVGRPSNIGQAQPIIDQLAEEARAFNR 227

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           + VA++   L+    + +   FG ++ C L     TG+ KGYGF EY K  S+  A S +
Sbjct: 228 IYVASVHQDLSDDDIKSVFEAFGKIKSCTLARDPTTGKHKGYGFIEYEKAQSSQDAVSSM 287

Query: 211 LGKPLGPRTLYV 222
               LG + L V
Sbjct: 288 NLFDLGGQYLRV 299


>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
          Length = 1336

 Score = 59.3 bits (142), Expect = 1e-08
 Identities = 107/363 (29%), Positives = 136/363 (37%), Gaps = 74/363 (20%)

Query: 366 PLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQLALQTQG-QKKPGILGDSPLGAL-QP 423
           P LH   GG QG +G  P  P   GP       Q     QG Q+ PG  G  PLG    P
Sbjct: 640 PPLHQGGGGPQGFMG--PQGP--QGPPQGLPRPQDMHGPQGMQRHPGPHG--PLGPQGPP 693

Query: 424 GAQPANPLLGELPAGGGLPPELPPRRG-KPPPLLPSVLGPAGGDREALGLGPPAAQ-LTP 481
           G Q ++   G +   G  PP      G + PP     LGP G        GPP  + +  
Sbjct: 694 GPQGSSGPQGHMGPQG--PPGPQGHIGPQGPPGPQGHLGPQGPPGTQGMQGPPGPRGMQG 751

Query: 482 PPAPVGLRGS----------------GL--RGLQKDSGPL----PTPPGVSLLGEPPKDY 519
           PP P G++G                 GL  RG+Q   GP     P P G+ ++G PP++ 
Sbjct: 752 PPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGM-IMGHPPQEM 810

Query: 520 RIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLK 579
           R P +P   L    P      +E RG  G      P +G    PP    G   S     +
Sbjct: 811 RGP-HPPGGLLGHGPQEMRGPQEIRGMQGP-----PPQGSMLGPPQELRGPPGS-----Q 859

Query: 580 SRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSG 639
           S+   P  S   PP+ G+        P   G        + PA GPH       S  P  
Sbjct: 860 SQQGPPQGSLGPPPQGGMQGP-----PGPQG-------QQNPARGPH------PSQGPIP 901

Query: 640 FGERSSGGSGGGPLSHF-YSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSP 698
           F ++ +   G GP + F   G  T      L  GL Q      I   PL  G+G     P
Sbjct: 902 FQQQKTPLLGDGPRAPFNQEGQSTG--PPPLIPGLGQQGAQGRI--PPLNPGQG-----P 952

Query: 699 GPN 701
           GPN
Sbjct: 953 GPN 955



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 76/296 (25%), Positives = 107/296 (36%), Gaps = 68/296 (22%)

Query: 374 GKQGLLG--APPAMPLLNGPALSTALLQLALQTQGQKKP-GILGDSPLGALQPGAQPANP 430
           G QG LG   PP    + GP     +       QG   P GI G      +Q G     P
Sbjct: 724 GPQGHLGPQGPPGTQGMQGPPGPRGM-------QGPPHPHGIQGGPGSQGIQ-GPVSQGP 775

Query: 431 LLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRG 490
           L+G  P G   PP     +G  P              + + +G P  ++  P  P GL G
Sbjct: 776 LMGLNPRGMQGPPGPRENQGPAP--------------QGMIMGHPPQEMRGPHPPGGLLG 821

Query: 491 SG---LRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWG 547
            G   +RG Q+  G    PP  S+LG PP++ R P                 G +++   
Sbjct: 822 HGPQEMRGPQEIRGMQGPPPQGSMLG-PPQELRGP----------------PGSQSQQGP 864

Query: 548 GAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPS 607
             G    P +G    PP P G  + ++     S+   P    + P    L D        
Sbjct: 865 PQGSLGPPPQGGMQGPPGPQGQQNPARG-PHPSQGPIPFQQQKTPL---LGD-------- 912

Query: 608 DMGPRRLFSH--------PREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSH 655
             GPR  F+         P  P LG  G ++ ++ P   G G   + G   GP +H
Sbjct: 913 --GPRAPFNQEGQSTGPPPLIPGLGQQG-AQGRIPPLNPGQGPGPNKGDSRGPPNH 965



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 77/342 (22%), Positives = 105/342 (30%), Gaps = 56/342 (16%)

Query: 413 LGDSPLGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPP------PLLPSVLGPAGGD 466
           L    +  +QP      PLLG  P  G  P    P+  + P      P+  + +GP G  
Sbjct: 564 LAQKQVEQIQPPPSSGTPLLGPQPFPGQGPMSQIPQGFQQPHPSQQMPMNMAQMGPPGPQ 623

Query: 467 REALGLGPPAAQLTPPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIP--LN 524
            +    GP   Q+ P   P+   G G +G     GP   P G+      P+D   P  + 
Sbjct: 624 GQFRPPGPQG-QMGPQGPPLHQGGGGPQGFMGPQGPQGPPQGL----PRPQDMHGPQGMQ 678

Query: 525 PYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGP-----PTNPPAPGG--GSSSSKAFQ 577
            +   H  L      G +           +   GP     P  PP P G  G       Q
Sbjct: 679 RHPGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQGHIGPQGPPGPQGHLGPQGPPGTQ 738

Query: 578 LKSRLLSPLSSARLPPEP----GLSDSYSFDYPSDMGP---------------------- 611
                  P    + PP P    G   S     P   GP                      
Sbjct: 739 GMQGPPGP-RGMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPA 797

Query: 612 --RRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGSPTSY-FTSG 668
               +  HP +   GPH P       P    G +   G  G P      G P       G
Sbjct: 798 PQGMIMGHPPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPG 857

Query: 669 LQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTP 710
            Q+  +Q     ++G  P G  +G     PGP G  +  + P
Sbjct: 858 SQS--QQGPPQGSLGPPPQGGMQG----PPGPQGQQNPARGP 893



 Score = 35.0 bits (79), Expect = 0.26
 Identities = 76/296 (25%), Positives = 97/296 (32%), Gaps = 79/296 (26%)

Query: 438  GGGLPPELPPRRGKP-PPLLPSVLGPAGGDREALGLGPPAAQLTPPPA----PVGLRGSG 492
            GG LP E   RRG P PP  P     + GD      GPP A     P     P       
Sbjct: 1036 GGPLPQEEKWRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPR 1095

Query: 493  LRGLQKDSGPLPTPPGVSLLGEP--------PKDYRIPLN-------------------- 524
             RG +++S     PP       P        P+D+    N                    
Sbjct: 1096 FRGRREESFRRGAPPRHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGT 1155

Query: 525  PYLNLHSLLPASN-----LAGKEARGWGGAGRSRRPAEG--------PPTNPPAPGGGSS 571
            P      LLP  +       G++   W G   +R P  G         P +PP  G    
Sbjct: 1156 PRGGRKGLLPTPDEFPRFEGGRKPDSWDG---NREPGPGHEHFRDTPRPDHPPHDG---- 1208

Query: 572  SSKAFQLKSRLLSPLSSARLPPE-------PGLSDSYSFDYP----SDMG---------P 611
             S A + +S  L  +  A LPP        PG S+    + P     D G          
Sbjct: 1209 HSPASRERSSSLQGMDMASLPPRKRPWHDGPGTSEHREMEAPGGPSEDRGGKGRGGPGPA 1268

Query: 612  RRLFSHPREPAL-GPHGPSRHKMSP--PPSGFGERSSGGSGG---GPLSHFYSGSP 661
            +R+    R  +L G H    H+  P   P G G  S GG  G   G  S+  SG P
Sbjct: 1269 QRVPKSGRSSSLDGEHHDGYHRDEPFGGPPGSGTPSRGGRSGSNWGRGSNMNSGPP 1324



 Score = 32.0 bits (71), Expect = 2.2
 Identities = 46/190 (24%), Positives = 60/190 (31%), Gaps = 27/190 (14%)

Query: 555 PAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRL 614
           P+ G P   P P  G             +S +      P P      +       GP+  
Sbjct: 576 PSSGTPLLGPQPFPGQGP----------MSQIPQGFQQPHPSQQMPMNMAQMGPPGPQGQ 625

Query: 615 FSHPR-EPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGL 673
           F  P  +  +GP GP  H+    P GF      G  G P      G P      G Q   
Sbjct: 626 FRPPGPQGQMGPQGPPLHQGGGGPQGF--MGPQGPQGPP-----QGLPRPQDMHGPQGMQ 678

Query: 674 KQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAHLLPSPEPSPEGSY 733
           +       +G       +G    S GP GH    + P G Q     H+ P   P P+G  
Sbjct: 679 RHPGPHGPLGPQGPPGPQG----SSGPQGHMG-PQGPPGPQ----GHIGPQGPPGPQGHL 729

Query: 734 VGQHSQGLGG 743
             Q   G  G
Sbjct: 730 GPQGPPGTQG 739


>gi|38201714 ELAV-like 1 [Homo sapiens]
          Length = 326

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 14/156 (8%)

Query: 75  RRKILIRGLPGDVTNQEVHDLLS---DYELKYCFVDKYKGTA----FVTLLNGEQAEAAI 127
           R  +++  LP ++T  E+  L S   + E      DK  G +    FV  +  + AE AI
Sbjct: 19  RTNLIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAI 78

Query: 128 NAFHQSRLRERELSVQL-QPT-----DALLCVANLPPSLTQQQFEELVRPFGSLERCFLV 181
           N  +  RL+ + + V   +P+     DA L ++ LP ++TQ+  E++   FG +    ++
Sbjct: 79  NTLNGLRLQSKTIKVSYARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRVL 138

Query: 182 YSERTGQSKGYGFAEYMKKDSAARAKSDLLG-KPLG 216
             + TG S+G  F  + K+  A  A +   G KP G
Sbjct: 139 VDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPG 174



 Score = 47.4 bits (111), Expect = 5e-05
 Identities = 44/181 (24%), Positives = 75/181 (41%), Gaps = 7/181 (3%)

Query: 151 LCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDL 210
           L V  LP ++TQ +   L    G +E   L+  +  G S GYGF  Y+    A RA + L
Sbjct: 22  LIVNYLPQNMTQDELRSLFSSIGEVESAKLIRDKVAGHSLGYGFVNYVTAKDAERAINTL 81

Query: 211 LGKPLGPRTLYVHWTDAGQLTPALLHSRCLCVDRLPPGF--NDVDALCRALSAVHSPTFC 268
            G  L  +T+ V +    + +  ++    L +  LP      DV+ +      + +    
Sbjct: 82  NGLRLQSKTIKVSY---ARPSSEVIKDANLYISGLPRTMTQKDVEDMFSRFGRIINSRV- 137

Query: 269 QLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRVSFCAPGPPGRSMLAALI 328
            L     G  +G A + ++    AEEA    +G    GS   ++      P ++   AL+
Sbjct: 138 -LVDQTTGLSRGVAFIRFDKRSEAEEAITSFNGHKPPGSSEPITVKFAANPNQNKNVALL 196

Query: 329 A 329
           +
Sbjct: 197 S 197



 Score = 32.7 bits (73), Expect = 1.3
 Identities = 17/56 (30%), Positives = 28/56 (50%)

Query: 167 ELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAKSDLLGKPLGPRTLYV 222
           ++  PFG++    ++    T + KG+GF      + AA A + L G  LG + L V
Sbjct: 262 QMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYEEAAMAIASLNGYRLGDKILQV 317



 Score = 30.0 bits (66), Expect = 8.3
 Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 8/61 (13%)

Query: 85  GDVTNQEVHDLLSDYELKYCFVDKYKGTAFVTLLNGEQAEAAINAFHQSRLRERELSVQL 144
           G VTN +V   + D+    C     KG  FVT+ N E+A  AI + +  RL ++ L V  
Sbjct: 268 GAVTNVKV---IRDFNTNKC-----KGFGFVTMTNYEEAAMAIASLNGYRLGDKILQVSF 319

Query: 145 Q 145
           +
Sbjct: 320 K 320


>gi|119829187 alpha 1 type XVII collagen [Homo sapiens]
          Length = 1497

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 109/401 (27%), Positives = 132/401 (32%), Gaps = 113/401 (28%)

Query: 339  KGLLPEPNILQLLNNLGPSASLQLL--LNPLLHGSAGGKQGLLGAP-----------PAM 385
            +GL  EP +  L   +G   +   +    P  H    G+QGL G P           P  
Sbjct: 718  RGLTGEPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPGK 777

Query: 386  PLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLPPEL 445
            P L GP     L      T G  +PGI G+   GA  PG    +     L   G  PP  
Sbjct: 778  PGLTGPQGPQGLPG----TPG--RPGIKGEP--GA--PGKIVTSEGSSMLTVPG--PPGP 825

Query: 446  PPRRGKP-PPLLPSVLGPAG--GDREALGL----------GPPAAQLTPPPAPVGLRGSG 492
            P   G P PP  P   GPAG  G +E L L          GPP   +  PP P G  G G
Sbjct: 826  PGAMGPPGPPGAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEG 885

Query: 493  LRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRS 552
                      LP PPG                         P S L+  E    G  G  
Sbjct: 886  ----------LPGPPGP------------------------PGSFLSNSETFLSGPPGPP 911

Query: 553  RRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDM-GP 611
              P       PP P G                          PG S S S  +  ++ GP
Sbjct: 912  GPPGPKGDQGPPGPRGHQGEQGL-------------------PGFSTSGSSSFGLNLQGP 952

Query: 612  RRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFY----------SGSP 661
                  P  P  GP GP   K  P   G     SG S GG  S  Y           G P
Sbjct: 953  ------PGPP--GPQGPKGDKGDPGVPGALGIPSGPSEGGSSSTMYVSGPPGPPGPPGPP 1004

Query: 662  TSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNG 702
             S  +SG +    Q ++S+ + S  + S    +   PGP G
Sbjct: 1005 GSISSSGQEI---QQYISEYMQSDSIRSYLSGVQGPPGPPG 1042



 Score = 47.0 bits (110), Expect = 7e-05
 Identities = 114/438 (26%), Positives = 141/438 (32%), Gaps = 86/438 (19%)

Query: 365 NPLLHGSAGGKQGLLGAP--------PAMPLLNGPALSTALLQLALQTQGQKKPGILG-- 414
           N  L GS G K G +G+P        P  P + GP           Q      PG+ G  
Sbjct: 562 NGNLRGSPGPK-GDMGSPGPKGDRGFPGTPGIPGPLGHPGPQGPKGQKGSVGDPGMEGPM 620

Query: 415 -----DSPLGALQPGAQPANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREA 469
                + P+G       P +   GE  A G   P  PP        +P  +GP G     
Sbjct: 621 GQRGREGPMGPRGEAGPPGSGEKGERGAAGEPGPHGPPG-------VPGSVGPKGSS--- 670

Query: 470 LGLGPPAAQLTPPPAPVGLRG----SGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNP 525
              G P  Q   PP PVGL+G     GL G++ D GP+  PPG    G+  +     L  
Sbjct: 671 ---GSPGPQ--GPPGPVGLQGLRGEVGLPGVKGDKGPM-GPPGPK--GDQGEKGPRGLTG 722

Query: 526 YLNLHSLLPASNLAG-KEARGWGG-----AGRSRRPAEGPP--TNPPAPGGGSSSSKAFQ 577
              +  L  A    G K A G  G       R  +   G P    PP P G         
Sbjct: 723 EPGMRGLPGAVGEPGAKGAMGPAGPDGHQGPRGEQGLTGMPGIRGPPGPSGDPG------ 776

Query: 578 LKSRLLSPLSSARLPPEPG----------------LSDSYSFDYPSDMGPRRLFSHPREP 621
            K  L  P     LP  PG                   S     P   GP      P  P
Sbjct: 777 -KPGLTGPQGPQGLPGTPGRPGIKGEPGAPGKIVTSEGSSMLTVPGPPGPPGAMGPPGPP 835

Query: 622 -ALGPHGPS---RHK----MSPPPSGFGERSSGGSG----GGPLSHFYSGSPTSYFTSGL 669
            A GP GP+    H+    +  PP   G R   G       GP      G P      G 
Sbjct: 836 GAPGPAGPAGLPGHQEVLNLQGPPGPPGPRGPPGPSIPGPPGPRGPPGEGLPGPPGPPGS 895

Query: 670 QAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQKRSFAHLL----PSP 725
                ++ LS   G       +G  G  PGP GH      P      S +  L    P  
Sbjct: 896 FLSNSETFLSGPPGPPGPPGPKGDQG-PPGPRGHQGEQGLPGFSTSGSSSFGLNLQGPPG 954

Query: 726 EPSPEGSYVGQHSQGLGG 743
            P P+G    +   G+ G
Sbjct: 955 PPGPQGPKGDKGDPGVPG 972


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 57.0 bits (136), Expect = 6e-08
 Identities = 91/361 (25%), Positives = 118/361 (32%), Gaps = 54/361 (14%)

Query: 373 GGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLL 432
           GG +     PP  P    P    +    +   + Q  P   G+ P G   P  +P  P  
Sbjct: 85  GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-- 142

Query: 433 GELPAGGGLPPELPPRRGKP--PPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRG 490
              P  GG  P+ PP  GKP  PP       P G ++      PP     PPP       
Sbjct: 143 ---PPQGGNKPQGPPPPGKPQGPP-------PQGDNKSRSSRSPPGKPQGPPP------- 185

Query: 491 SGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAG 550
              +G  +  GP P PPG    G PP+    P  P        P     G   +G   + 
Sbjct: 186 ---QGGNQPQGP-PPPPG-KPQGPPPQGGNKPQGP-------PPPGKPQGPPPQGDNKSQ 233

Query: 551 RSRRP---AEGPPTN--------PPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSD 599
            +R P    +GPP          PP PG           K +   P    + PP  G S 
Sbjct: 234 SARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 293

Query: 600 SYSFDYP--SDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSG----GSGGGPL 653
           S S   P     GP     +  +   GP  P      PPP G G +  G    G   GP 
Sbjct: 294 SRSSRSPPGKPQGPPPQGGNQPQ---GPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPP 349

Query: 654 SHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGG 713
               S S ++    G   G  Q   +   G  P   G      +P         + P GG
Sbjct: 350 PQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409

Query: 714 Q 714
           +
Sbjct: 410 R 410



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 100/377 (26%), Positives = 128/377 (33%), Gaps = 73/377 (19%)

Query: 393 LSTALLQLAL------QTQGQKKPGILGDSPLGAL-QPGAQPANPLL------GELPAGG 439
           LS ALL L+           ++ P ++  +P GA  Q G +P  P        G  P GG
Sbjct: 6   LSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGG 65

Query: 440 GLPPELPPRRGKP--PPLLPSVLGPAGGDREALGLGPPAAQLTPPP---------APVGL 488
             P   PP  GKP  PP       P GG++   G  PP     PPP         +P G 
Sbjct: 66  NQPQGPPPPPGKPQGPP-------PQGGNKPQ-GPPPPGKPQGPPPQGDKSRSPRSPPGK 117

Query: 489 -RGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWG 547
            +G   +G  +  GP P PPG    G PP+    P  P        P     G   +G  
Sbjct: 118 PQGPPPQGGNQPQGP-PPPPG-KPQGPPPQGGNKPQGP-------PPPGKPQGPPPQGDN 168

Query: 548 GAGRSRRP---AEGPPTN--------PPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPG 596
            +  SR P    +GPP          PP PG           K +   P    + PP  G
Sbjct: 169 KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 228

Query: 597 LSDSYSFDYP--SDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGPLS 654
            + S S   P     GP     +  +   GP  P      PPP G  +       G P  
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQ---GPPPPPGKPQGPPPQGGNKPQGPPPPGKP-- 283

Query: 655 HFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHSHLLKTPLGGQ 714
               G P      G ++   +S   K  G  P G  +      P P         P GG 
Sbjct: 284 ---QGPPPQ---GGSKSRSSRSPPGKPQGPPPQGGNQ---PQGPPPPPGKPQGPPPQGGN 334

Query: 715 KRSFAHLLPSPEPSPEG 731
           K       P P   P+G
Sbjct: 335 KPQG----PPPPGKPQG 347


>gi|15890086 type IV collagen alpha 5 isoform 2 precursor [Homo
            sapiens]
          Length = 1691

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 136/480 (28%), Positives = 171/480 (35%), Gaps = 85/480 (17%)

Query: 313  FCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSA 372
            F  PGP G   +      Q  A N G+  +P P          P  ++     P L G+ 
Sbjct: 625  FGPPGPVGEKGI------QGVAGNPGQPGIPGPKG-------DPGQTITQPGKPGLPGNP 671

Query: 373  G--GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQKK--PGILGDSPLGALQP 423
            G  G  GL G P     P +P + G      +  + L      K  PGI G        P
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGP-------P 724

Query: 424  GAQPANPLLG-ELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTP- 481
            GA      +G E P G   PP  P  +G+P   LP   GP G       LGP   +  P 
Sbjct: 725  GAPGTPGRIGLEGPPG---PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 482  PPAPVGLRG-SGLRGLQKDSGPLPTP--------PGVSLLGEP-PKDYRIPLNPYLNLHS 531
            PP P G  G  GL G + D GP   P        PG+ + G P P     P+     LH 
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG-QPGLHG 840

Query: 532  L--------LPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPG-GGSSSSKAFQLKSR 581
            +         P  ++ G    RG  G   +  P  GPP +P  PG  G+S     + +  
Sbjct: 841  IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMG 899

Query: 582  LL------SPLSSARLPPEPGL-SDSYSFDYPSDMGPRRLFSHPREPAL-GPHGPSRHKM 633
            ++       PL        PGL  D      P   GP        EP L GP GP     
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM---- 955

Query: 634  SPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGL 693
               P+  G +   G  G P     SG P  Y   GL     Q  LS   G   L    G 
Sbjct: 956  --DPNLLGSKGEKGEPGLPGIPGVSG-PKGY--QGLPGDPGQPGLS---GQPGLPGPPGP 1007

Query: 694  LGLSPGPNGHSHLLKTPLGGQKRSFAHL-LPSPE-----PSPEGSYVGQHSQGLGGHYAD 747
             G +PG  G   L+  P  G K +   +  P P+     P P G      S GL G   D
Sbjct: 1008 KG-NPGLPGQPGLIGPP--GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 109/400 (27%), Positives = 136/400 (34%), Gaps = 88/400 (22%)

Query: 316  PGPPGRSMLAALIAAQATALNRGK-GLLPEPNI--LQLLNNLGPSASLQLLLNPLLHGSA 372
            PGPPGR+ L  L   +      G+ G +  P +  + +    GP      +  P LHG  
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 373  G-------------------GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQK 408
            G                   G  G+ GAP     P  P L G A ++       +     
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 409  KPGILGDSPLGALQPGAQPANPLLGE--LPAGGGLP-----------PELPPRRGKPPPL 455
             PG  G  PLG   PG      L G+  L    GLP           P LP   G P P+
Sbjct: 903  PPGPPG--PLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP---GPPGPM 955

Query: 456  LPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGS-GLRGLQKDSGPLPTPPGVSLLGE 514
             P++LG  G   E  GL P    ++ P    GL G  G  GL    G LP PPG      
Sbjct: 956  DPNLLGSKGEKGEP-GL-PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPG------ 1006

Query: 515  PPKDYRIPLNPYLNLHSLLPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPGGGSSSS 573
            P  +  +P  P      L+    L G     G+ G     +  EGPP     PG   S  
Sbjct: 1007 PKGNPGLPGQP-----GLIGPPGLKGTIGDMGFPGP----QGVEGPPGPSGVPGQPGSPG 1057

Query: 574  KAFQLKSRLLSPLSSARLPPEPGLSDSYSF-DYPSDMGPRRLFSHPREPAL--------- 623
               Q   +    +SS  LP  PG         YP + G +     P  P L         
Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 624  ----------GPHGPSRHKMSPPPSGF-GERSSGGSGGGP 652
                      GP GP      P   G  GE    G GG P
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 92/347 (26%), Positives = 116/347 (33%), Gaps = 87/347 (25%)

Query: 355 GPSASLQLLLNPLLHGSAGGKQGLLG--APPAMPLLNGPALSTALLQLALQTQGQK---- 408
           GP   +     P+      G QGL G   PP  P + GP       +     QG+     
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 409 KPGILGDSPLGALQPGAQ--PANPLL-------GELPAGGGLPPELPPRRGKPPPLLPSV 459
           KPG  G++     QPG    P +P         GE    G   P  PP    P P     
Sbjct: 299 KPGKDGENG----QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354

Query: 460 LGPAG-----------GDREALGL-------GPPAAQLTPPPAPVGLRGSGLRGLQKDSG 501
           +G  G           G+R   G+       GPP A +  PP P G  G   RG + D G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEG 412

Query: 502 PLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAE---- 557
               PPG+S+ G P             L     A  L G      G AG    P++    
Sbjct: 413 ----PPGISIPGPP------------GLDGQPGAPGLPGPP----GPAGPHIPPSDEICE 452

Query: 558 -GPPTNPPAPGG----------GSSSSKAFQ-LKSRLLSPLSSARLPPEPGLSDSYSFDY 605
            GPP  P +PG           G      F  + + +  P     LP  PG   S  F  
Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF-- 510

Query: 606 PSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGP 652
           P   G +      +  A GP G      +P   GF      GS G P
Sbjct: 511 PGQKGEK-----GQAGATGPKGLPGIPGAPGAPGF-----PGSKGEP 547



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 89/338 (26%), Positives = 120/338 (35%), Gaps = 46/338 (13%)

Query: 410 PGILGD-SPLGALQPGAQPANPLLGELPAGGGLP--PELPPRRGKPPPL-LPSVLGPAGG 465
           PG+ G   P G      +P + ++  LP   G P  P  P  +G P P  +P  +GP G 
Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 466 DREALGLGPPAAQLTP-PPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLN 524
                 +GPP     P P   +GL   G +G + + G L  PPG      PP        
Sbjct: 200 PGL---MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG-LQGPPG------PPGQISEQKR 249

Query: 525 PYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPP--TNPPAPGGGSSSSKAFQLKSRL 582
           P            +  +  +G  G    R P  GPP    PP P GG    K  Q +   
Sbjct: 250 P------------IDVEFQKGDQGLPGDRGP-PGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 583 LSPLSSARLPPEPGLSDSYSFDYPSDMG----PRRLFSHPREPALGPHGPSRHKMSPPPS 638
                      +PG+        P D G    P R     ++   GP GP    +  P +
Sbjct: 297 RGKPGKDGENGQPGIP-----GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 639 G--FGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGL 696
           G   GE+ + G  G P      G P      GL  G   + +    G        G  G 
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL-PGPPGAAVMGPPGPPGFPGERGQKG- 409

Query: 697 SPGPNGHSHLLKTPLGGQKRSFAHLLPSPEPSPEGSYV 734
             GP G S  +  P G   +  A  LP P P P G ++
Sbjct: 410 DEGPPGIS--IPGPPGLDGQPGAPGLPGP-PGPAGPHI 444



 Score = 37.7 bits (86), Expect = 0.040
 Identities = 105/406 (25%), Positives = 129/406 (31%), Gaps = 102/406 (25%)

Query: 365  NPLLHGSAG--GKQGLLGAP--------PAMPLLNGPALSTALLQLALQTQGQKKPGILG 414
            NP + GS G  G  GL G P        P  P   GP     +      +     PG+ G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI------SGPPGNPGLPG 1146

Query: 415  D-SPLGALQPGAQPANPLLGELPAGGGLP--------PELPPRRGKPPPLLPSVLGPAG- 464
            +  P+G      QP  P     P   G+P        P  P      PP LP + G  G 
Sbjct: 1147 EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206

Query: 465  ----GDREALGLGPPAAQ--------LTPPPAPVGLRGSGLRGLQKDSGP-----LPTPP 507
                G     GL  P  +        +  PP P G  G  L G + + GP      P P 
Sbjct: 1207 GGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGPT 1266

Query: 508  GVSLLGEPPKDYRIPLNPYLNLHSLLPAS-------NLAGKEARGWGGAGRSRRPA---- 556
            G   L  P     +P N  +      P          L G +    G  G   RP     
Sbjct: 1267 GFQGLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP-GLQGNPGRPGLNGM 1325

Query: 557  EGPPTNPPAPG-------GGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDM 609
            +G P  P  PG        G   S   + +  L+ P     LP   G     S     D 
Sbjct: 1326 KGDPGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG----QSIIIKGDA 1381

Query: 610  GPRRLFSHPREPAL----GPHGPSRHKMSPPPSGFGERS-------SGGSGGGPLSHFYS 658
            GP  +   P +P L    GP GP        P G   R+       +GG  G P      
Sbjct: 1382 GPPGI---PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP------ 1432

Query: 659  GSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHS 704
            G P    T GL                P G  +GL G  PGP G S
Sbjct: 1433 GLPGQPGTRGL--------------DGPPGP-DGLQG-PPGPPGTS 1462


>gi|4502955 type IV collagen alpha 5 isoform 1 precursor [Homo
            sapiens]
          Length = 1685

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 136/480 (28%), Positives = 171/480 (35%), Gaps = 85/480 (17%)

Query: 313  FCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSA 372
            F  PGP G   +      Q  A N G+  +P P          P  ++     P L G+ 
Sbjct: 625  FGPPGPVGEKGI------QGVAGNPGQPGIPGPKG-------DPGQTITQPGKPGLPGNP 671

Query: 373  G--GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQKK--PGILGDSPLGALQP 423
            G  G  GL G P     P +P + G      +  + L      K  PGI G        P
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGP-------P 724

Query: 424  GAQPANPLLG-ELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTP- 481
            GA      +G E P G   PP  P  +G+P   LP   GP G       LGP   +  P 
Sbjct: 725  GAPGTPGRIGLEGPPG---PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 482  PPAPVGLRG-SGLRGLQKDSGPLPTP--------PGVSLLGEP-PKDYRIPLNPYLNLHS 531
            PP P G  G  GL G + D GP   P        PG+ + G P P     P+     LH 
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG-QPGLHG 840

Query: 532  L--------LPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPG-GGSSSSKAFQLKSR 581
            +         P  ++ G    RG  G   +  P  GPP +P  PG  G+S     + +  
Sbjct: 841  IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMG 899

Query: 582  LL------SPLSSARLPPEPGL-SDSYSFDYPSDMGPRRLFSHPREPAL-GPHGPSRHKM 633
            ++       PL        PGL  D      P   GP        EP L GP GP     
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM---- 955

Query: 634  SPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGL 693
               P+  G +   G  G P     SG P  Y   GL     Q  LS   G   L    G 
Sbjct: 956  --DPNLLGSKGEKGEPGLPGIPGVSG-PKGY--QGLPGDPGQPGLS---GQPGLPGPPGP 1007

Query: 694  LGLSPGPNGHSHLLKTPLGGQKRSFAHL-LPSPE-----PSPEGSYVGQHSQGLGGHYAD 747
             G +PG  G   L+  P  G K +   +  P P+     P P G      S GL G   D
Sbjct: 1008 KG-NPGLPGQPGLIGPP--GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 109/400 (27%), Positives = 136/400 (34%), Gaps = 88/400 (22%)

Query: 316  PGPPGRSMLAALIAAQATALNRGK-GLLPEPNI--LQLLNNLGPSASLQLLLNPLLHGSA 372
            PGPPGR+ L  L   +      G+ G +  P +  + +    GP      +  P LHG  
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 373  G-------------------GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQK 408
            G                   G  G+ GAP     P  P L G A ++       +     
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 409  KPGILGDSPLGALQPGAQPANPLLGE--LPAGGGLP-----------PELPPRRGKPPPL 455
             PG  G  PLG   PG      L G+  L    GLP           P LP   G P P+
Sbjct: 903  PPGPPG--PLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP---GPPGPM 955

Query: 456  LPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGS-GLRGLQKDSGPLPTPPGVSLLGE 514
             P++LG  G   E  GL P    ++ P    GL G  G  GL    G LP PPG      
Sbjct: 956  DPNLLGSKGEKGEP-GL-PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPG------ 1006

Query: 515  PPKDYRIPLNPYLNLHSLLPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPGGGSSSS 573
            P  +  +P  P      L+    L G     G+ G     +  EGPP     PG   S  
Sbjct: 1007 PKGNPGLPGQP-----GLIGPPGLKGTIGDMGFPGP----QGVEGPPGPSGVPGQPGSPG 1057

Query: 574  KAFQLKSRLLSPLSSARLPPEPGLSDSYSF-DYPSDMGPRRLFSHPREPAL--------- 623
               Q   +    +SS  LP  PG         YP + G +     P  P L         
Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 624  ----------GPHGPSRHKMSPPPSGF-GERSSGGSGGGP 652
                      GP GP      P   G  GE    G GG P
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 92/347 (26%), Positives = 116/347 (33%), Gaps = 87/347 (25%)

Query: 355 GPSASLQLLLNPLLHGSAGGKQGLLG--APPAMPLLNGPALSTALLQLALQTQGQK---- 408
           GP   +     P+      G QGL G   PP  P + GP       +     QG+     
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 409 KPGILGDSPLGALQPGAQ--PANPLL-------GELPAGGGLPPELPPRRGKPPPLLPSV 459
           KPG  G++     QPG    P +P         GE    G   P  PP    P P     
Sbjct: 299 KPGKDGENG----QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354

Query: 460 LGPAG-----------GDREALGL-------GPPAAQLTPPPAPVGLRGSGLRGLQKDSG 501
           +G  G           G+R   G+       GPP A +  PP P G  G   RG + D G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEG 412

Query: 502 PLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAE---- 557
               PPG+S+ G P             L     A  L G      G AG    P++    
Sbjct: 413 ----PPGISIPGPP------------GLDGQPGAPGLPGPP----GPAGPHIPPSDEICE 452

Query: 558 -GPPTNPPAPGG----------GSSSSKAFQ-LKSRLLSPLSSARLPPEPGLSDSYSFDY 605
            GPP  P +PG           G      F  + + +  P     LP  PG   S  F  
Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF-- 510

Query: 606 PSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGP 652
           P   G +      +  A GP G      +P   GF      GS G P
Sbjct: 511 PGQKGEK-----GQAGATGPKGLPGIPGAPGAPGF-----PGSKGEP 547



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 89/338 (26%), Positives = 120/338 (35%), Gaps = 46/338 (13%)

Query: 410 PGILGD-SPLGALQPGAQPANPLLGELPAGGGLP--PELPPRRGKPPPL-LPSVLGPAGG 465
           PG+ G   P G      +P + ++  LP   G P  P  P  +G P P  +P  +GP G 
Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 466 DREALGLGPPAAQLTP-PPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLN 524
                 +GPP     P P   +GL   G +G + + G L  PPG      PP        
Sbjct: 200 PGL---MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG-LQGPPG------PPGQISEQKR 249

Query: 525 PYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPP--TNPPAPGGGSSSSKAFQLKSRL 582
           P            +  +  +G  G    R P  GPP    PP P GG    K  Q +   
Sbjct: 250 P------------IDVEFQKGDQGLPGDRGP-PGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 583 LSPLSSARLPPEPGLSDSYSFDYPSDMG----PRRLFSHPREPALGPHGPSRHKMSPPPS 638
                      +PG+        P D G    P R     ++   GP GP    +  P +
Sbjct: 297 RGKPGKDGENGQPGIP-----GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 639 G--FGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGL 696
           G   GE+ + G  G P      G P      GL  G   + +    G        G  G 
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL-PGPPGAAVMGPPGPPGFPGERGQKG- 409

Query: 697 SPGPNGHSHLLKTPLGGQKRSFAHLLPSPEPSPEGSYV 734
             GP G S  +  P G   +  A  LP P P P G ++
Sbjct: 410 DEGPPGIS--IPGPPGLDGQPGAPGLPGP-PGPAGPHI 444



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 105/401 (26%), Positives = 129/401 (32%), Gaps = 98/401 (24%)

Query: 365  NPLLHGSAG--GKQGLLGAP--------PAMPLLNGPALSTALLQLALQTQGQKKPGILG 414
            NP + GS G  G  GL G P        P  P   GP     +      +     PG+ G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI------SGPPGNPGLPG 1146

Query: 415  D-SPLGALQPGAQPANPLLGELPAGGGLP--------PELPPRRGKPPPLLPSVLGPAG- 464
            +  P+G      QP  P     P   G+P        P  P      PP LP + G  G 
Sbjct: 1147 EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206

Query: 465  ----GDREALGLGPPAAQ--------LTPPPAPVGLRGSGLRGLQKDSGPLPTPPGVSLL 512
                G     GL  P  +        +  PP P G  G  L G + + GP   PPG   L
Sbjct: 1207 GGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGP-QGPPGRPGL 1265

Query: 513  GEPPKDYRIPLNPYLNLHSLLPAS-------NLAGKEARGWGGAGRSRRPA----EGPPT 561
              P     +P N  +      P          L G +    G  G   RP     +G P 
Sbjct: 1266 PGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP-GLQGNPGRPGLNGMKGDPG 1324

Query: 562  NPPAPG-------GGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRL 614
             P  PG        G   S   + +  L+ P     LP   G     S     D GP  +
Sbjct: 1325 LPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG----QSIIIKGDAGPPGI 1380

Query: 615  FSHPREPAL----GPHGPSRHKMSPPPSGFGERS-------SGGSGGGPLSHFYSGSPTS 663
               P +P L    GP GP        P G   R+       +GG  G P      G P  
Sbjct: 1381 ---PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP------GLPGQ 1431

Query: 664  YFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHS 704
              T GL                P G  +GL G  PGP G S
Sbjct: 1432 PGTRGL--------------DGPPGP-DGLQG-PPGPPGTS 1456


>gi|15890088 type IV collagen alpha 5 isoform 3 precursor [Homo
            sapiens]
          Length = 1688

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 136/480 (28%), Positives = 171/480 (35%), Gaps = 85/480 (17%)

Query: 313  FCAPGPPGRSMLAALIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSA 372
            F  PGP G   +      Q  A N G+  +P P          P  ++     P L G+ 
Sbjct: 625  FGPPGPVGEKGI------QGVAGNPGQPGIPGPKG-------DPGQTITQPGKPGLPGNP 671

Query: 373  G--GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQKK--PGILGDSPLGALQP 423
            G  G  GL G P     P +P + G      +  + L      K  PGI G        P
Sbjct: 672  GRDGDVGLPGDPGLPGQPGLPGIPGSKGEPGIPGIGLPGPPGPKGFPGIPGP-------P 724

Query: 424  GAQPANPLLG-ELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTP- 481
            GA      +G E P G   PP  P  +G+P   LP   GP G       LGP   +  P 
Sbjct: 725  GAPGTPGRIGLEGPPG---PPGFPGPKGEPGFALPGPPGPPGLPGFKGALGPKGDRGFPG 781

Query: 482  PPAPVGLRG-SGLRGLQKDSGPLPTP--------PGVSLLGEP-PKDYRIPLNPYLNLHS 531
            PP P G  G  GL G + D GP   P        PG+ + G P P     P+     LH 
Sbjct: 782  PPGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIG-QPGLHG 840

Query: 532  L--------LPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPG-GGSSSSKAFQLKSR 581
            +         P  ++ G    RG  G   +  P  GPP +P  PG  G+S     + +  
Sbjct: 841  IPGEKGDPGPPGLDVPGPPGERGSPGIPGAPGPI-GPPGSPGLPGKAGASGFPGTKGEMG 899

Query: 582  LL------SPLSSARLPPEPGL-SDSYSFDYPSDMGPRRLFSHPREPAL-GPHGPSRHKM 633
            ++       PL        PGL  D      P   GP        EP L GP GP     
Sbjct: 900  MMGPPGPPGPLGIPGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLPGPPGPM---- 955

Query: 634  SPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGL 693
               P+  G +   G  G P     SG P  Y   GL     Q  LS   G   L    G 
Sbjct: 956  --DPNLLGSKGEKGEPGLPGIPGVSG-PKGY--QGLPGDPGQPGLS---GQPGLPGPPGP 1007

Query: 694  LGLSPGPNGHSHLLKTPLGGQKRSFAHL-LPSPE-----PSPEGSYVGQHSQGLGGHYAD 747
             G +PG  G   L+  P  G K +   +  P P+     P P G      S GL G   D
Sbjct: 1008 KG-NPGLPGQPGLIGPP--GLKGTIGDMGFPGPQGVEGPPGPSGVPGQPGSPGLPGQKGD 1064



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 109/400 (27%), Positives = 136/400 (34%), Gaps = 88/400 (22%)

Query: 316  PGPPGRSMLAALIAAQATALNRGK-GLLPEPNI--LQLLNNLGPSASLQLLLNPLLHGSA 372
            PGPPGR+ L  L   +      G+ G +  P +  + +    GP      +  P LHG  
Sbjct: 783  PGPPGRTGLDGLPGPKGDVGPNGQPGPMGPPGLPGIGVQGPPGPPGIPGPIGQPGLHGIP 842

Query: 373  G-------------------GKQGLLGAP-----PAMPLLNGPALSTALLQLALQTQGQK 408
            G                   G  G+ GAP     P  P L G A ++       +     
Sbjct: 843  GEKGDPGPPGLDVPGPPGERGSPGIPGAPGPIGPPGSPGLPGKAGASGFPGTKGEMGMMG 902

Query: 409  KPGILGDSPLGALQPGAQPANPLLGE--LPAGGGLP-----------PELPPRRGKPPPL 455
             PG  G  PLG   PG      L G+  L    GLP           P LP   G P P+
Sbjct: 903  PPGPPG--PLGI--PGRSGVPGLKGDDGLQGQPGLPGPTGEKGSKGEPGLP---GPPGPM 955

Query: 456  LPSVLGPAGGDREALGLGPPAAQLTPPPAPVGLRGS-GLRGLQKDSGPLPTPPGVSLLGE 514
             P++LG  G   E  GL P    ++ P    GL G  G  GL    G LP PPG      
Sbjct: 956  DPNLLGSKGEKGEP-GL-PGIPGVSGPKGYQGLPGDPGQPGLSGQPG-LPGPPG------ 1006

Query: 515  PPKDYRIPLNPYLNLHSLLPASNLAGKEA-RGWGGAGRSRRPAEGPPTNPPAPGGGSSSS 573
            P  +  +P  P      L+    L G     G+ G     +  EGPP     PG   S  
Sbjct: 1007 PKGNPGLPGQP-----GLIGPPGLKGTIGDMGFPGP----QGVEGPPGPSGVPGQPGSPG 1057

Query: 574  KAFQLKSRLLSPLSSARLPPEPGLSDSYSF-DYPSDMGPRRLFSHPREPAL--------- 623
               Q   +    +SS  LP  PG         YP + G +     P  P L         
Sbjct: 1058 LPGQKGDKGDPGISSIGLPGLPGPKGEPGLPGYPGNPGIKGSVGDPGLPGLPGTPGAKGQ 1117

Query: 624  ----------GPHGPSRHKMSPPPSGF-GERSSGGSGGGP 652
                      GP GP      P   G  GE    G GG P
Sbjct: 1118 PGLPGFPGTPGPPGPKGISGPPGNPGLPGEPGPVGGGGHP 1157



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 92/347 (26%), Positives = 116/347 (33%), Gaps = 87/347 (25%)

Query: 355 GPSASLQLLLNPLLHGSAGGKQGLLG--APPAMPLLNGPALSTALLQLALQTQGQK---- 408
           GP   +     P+      G QGL G   PP  P + GP       +     QG+     
Sbjct: 239 GPPGQISEQKRPIDVEFQKGDQGLPGDRGPPGPPGIRGPPGPPGGEKGEKGEQGEPGKRG 298

Query: 409 KPGILGDSPLGALQPGAQ--PANPLL-------GELPAGGGLPPELPPRRGKPPPLLPSV 459
           KPG  G++     QPG    P +P         GE    G   P  PP    P P     
Sbjct: 299 KPGKDGENG----QPGIPGLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGTGIT 354

Query: 460 LGPAG-----------GDREALGL-------GPPAAQLTPPPAPVGLRGSGLRGLQKDSG 501
           +G  G           G+R   G+       GPP A +  PP P G  G   RG + D G
Sbjct: 355 IGEKGNIGLPGLPGEKGERGFPGIQGPPGLPGPPGAAVMGPPGPPGFPGE--RGQKGDEG 412

Query: 502 PLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAE---- 557
               PPG+S+ G P             L     A  L G      G AG    P++    
Sbjct: 413 ----PPGISIPGPP------------GLDGQPGAPGLPGPP----GPAGPHIPPSDEICE 452

Query: 558 -GPPTNPPAPGG----------GSSSSKAFQ-LKSRLLSPLSSARLPPEPGLSDSYSFDY 605
            GPP  P +PG           G      F  + + +  P     LP  PG   S  F  
Sbjct: 453 PGPPGPPGSPGDKGLQGEQGVKGDKGDTCFNCIGTGISGPPGQPGLPGLPGPPGSLGF-- 510

Query: 606 PSDMGPRRLFSHPREPALGPHGPSRHKMSPPPSGFGERSSGGSGGGP 652
           P   G +      +  A GP G      +P   GF      GS G P
Sbjct: 511 PGQKGEK-----GQAGATGPKGLPGIPGAPGAPGF-----PGSKGEP 547



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 89/338 (26%), Positives = 120/338 (35%), Gaps = 46/338 (13%)

Query: 410 PGILGD-SPLGALQPGAQPANPLLGELPAGGGLP--PELPPRRGKPPPL-LPSVLGPAGG 465
           PG+ G   P G      +P + ++  LP   G P  P  P  +G P P  +P  +GP G 
Sbjct: 140 PGLQGPPGPPGIPGMKGEPGSIIMSSLPGPKGNPGYPGPPGIQGLPGPTGIPGPIGPPGP 199

Query: 466 DREALGLGPPAAQLTP-PPAPVGLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLN 524
                 +GPP     P P   +GL   G +G + + G L  PPG      PP        
Sbjct: 200 PGL---MGPPGPPGLPGPKGNMGLNFQGPKGEKGEQG-LQGPPG------PPGQISEQKR 249

Query: 525 PYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPP--TNPPAPGGGSSSSKAFQLKSRL 582
           P            +  +  +G  G    R P  GPP    PP P GG    K  Q +   
Sbjct: 250 P------------IDVEFQKGDQGLPGDRGP-PGPPGIRGPPGPPGGEKGEKGEQGEPGK 296

Query: 583 LSPLSSARLPPEPGLSDSYSFDYPSDMG----PRRLFSHPREPALGPHGPSRHKMSPPPS 638
                      +PG+        P D G    P R     ++   GP GP    +  P +
Sbjct: 297 RGKPGKDGENGQPGIP-----GLPGDPGYPGEPGRDGEKGQKGDTGPPGPPGLVIPRPGT 351

Query: 639 G--FGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGL 696
           G   GE+ + G  G P      G P      GL  G   + +    G        G  G 
Sbjct: 352 GITIGEKGNIGLPGLPGEKGERGFPGIQGPPGL-PGPPGAAVMGPPGPPGFPGERGQKG- 409

Query: 697 SPGPNGHSHLLKTPLGGQKRSFAHLLPSPEPSPEGSYV 734
             GP G S  +  P G   +  A  LP P P P G ++
Sbjct: 410 DEGPPGIS--IPGPPGLDGQPGAPGLPGP-PGPAGPHI 444



 Score = 38.9 bits (89), Expect = 0.018
 Identities = 105/403 (26%), Positives = 129/403 (32%), Gaps = 99/403 (24%)

Query: 365  NPLLHGSAG--GKQGLLGAP--------PAMPLLNGPALSTALLQLALQTQGQKKPGILG 414
            NP + GS G  G  GL G P        P  P   GP     +      +     PG+ G
Sbjct: 1093 NPGIKGSVGDPGLPGLPGTPGAKGQPGLPGFPGTPGPPGPKGI------SGPPGNPGLPG 1146

Query: 415  D-SPLGALQPGAQPANPLLGELPAGGGLP--------PELPPRRGKPPPLLPSVLGPAG- 464
            +  P+G      QP  P     P   G+P        P  P      PP LP + G  G 
Sbjct: 1147 EPGPVGGGGHPGQPGPPGEKGKPGQDGIPGPAGQKGEPGQPGFGNPGPPGLPGLSGQKGD 1206

Query: 465  ----GDREALGLGPPAAQ--------LTPPPAPVGLRGSGLRGLQKDSGPLPTP--PGVS 510
                G     GL  P  +        +  PP P G  G  L G + + GP   P  PG  
Sbjct: 1207 GGLPGIPGNPGLPGPKGEPGFHGFPGVQGPPGPPGSPGPALEGPKGNPGPQGPPGRPGFQ 1266

Query: 511  LLGEPPKDYRIPLNPYLNLHSLLPAS-------NLAGKEARGWGGAGRSRRPA----EGP 559
             L  P     +P N  +      P          L G +    G  G   RP     +G 
Sbjct: 1267 GLPGPEGPPGLPGNGGIKGEKGNPGQPGLPGLPGLKGDQGPP-GLQGNPGRPGLNGMKGD 1325

Query: 560  PTNPPAPG-------GGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPR 612
            P  P  PG        G   S   + +  L+ P     LP   G     S     D GP 
Sbjct: 1326 PGLPGVPGFPGMKGPSGVPGSAGPEGEPGLIGPPGPPGLPGPSG----QSIIIKGDAGPP 1381

Query: 613  RLFSHPREPAL----GPHGPSRHKMSPPPSGFGERS-------SGGSGGGPLSHFYSGSP 661
             +   P +P L    GP GP        P G   R+       +GG  G P      G P
Sbjct: 1382 GI---PGQPGLKGLPGPQGPQGLPGPTGPPGDPGRNGLPGFDGAGGRKGDP------GLP 1432

Query: 662  TSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGLSPGPNGHS 704
                T GL                P G  +GL G  PGP G S
Sbjct: 1433 GQPGTRGL--------------DGPPGP-DGLQG-PPGPPGTS 1459


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
            sapiens]
          Length = 1560

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 108/439 (24%), Positives = 151/439 (34%), Gaps = 94/439 (21%)

Query: 269  QLACGQDGQLKGFAVLEYETAEMAEEAQQQADGLSLGGSHLRV--SFCAPGPPGRSMLAA 326
            ++  GQ       A+L  ++ +M    ++    LS  G HL V  S     PP      A
Sbjct: 676  KIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP-----PA 730

Query: 327  LIAAQATALNRGKGLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMP 386
               A AT + +G GL P+    Q      P+ + Q+                   P A P
Sbjct: 731  QDPAPATPVAKGAGLGPQAPDSQA----SPAPAPQI-------------------PAAAP 767

Query: 387  LLN-GPALSTALLQLALQTQGQKKPGILGDSP-LGALQPGAQPANPLLGELPAGGGLPPE 444
            L   GP+ S +L   A           LGDSP L +  P   P+ P     P     PP 
Sbjct: 768  LKGPGPSSSPSLPHQAP----------LGDSPHLPSPHPTRPPSRP--PSRPQSVSRPPS 815

Query: 445  LPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTP----PPAPVGLRGSGLRGLQKDS 500
             PP    PPP  P  L      +  LG+ PPA+   P    PP P  LR       Q   
Sbjct: 816  EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQP-PLRPQS----QPPE 870

Query: 501  GPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPP 560
            GPLP  P +     PP      +       S LPA   +  + +          P++GP 
Sbjct: 871  GPLPPAPHL-----PPSSTSSAVASSSETSSRLPAPTPSDFQLQ--------FPPSQGPH 917

Query: 561  TNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSDSYSFDYPSDMGPRRLFSHPRE 620
             +P  P             +  L P  +A  PP P      +  +P+   P+ L      
Sbjct: 918  KSPTPP------------PTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALL----- 960

Query: 621  PALGPHGPSRHKMSPPPSG-FGERSSGGSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLS 679
                       +    PSG   +  +GG+   P +    G  TS   S L +G   S   
Sbjct: 961  ----------ERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTP 1010

Query: 680  KAIGSSPLGSGEGLLGLSP 698
             A   +P  +     GL P
Sbjct: 1011 TAPSHAPAPAPMAATGLPP 1029



 Score = 40.4 bits (93), Expect = 0.006
 Identities = 75/301 (24%), Positives = 97/301 (32%), Gaps = 31/301 (10%)

Query: 340 GLLPEPNILQLLNNLGPSASLQLLLNPLLHGSAGGKQGLLGAPPAMPLLNGPALSTALLQ 399
           G+ P+   L +  NL  + +  L  N +  G AG      G P   PL   P L ++ L 
Sbjct: 279 GVSPQGAGLVIQKNLSAAVATTLNGNSVF-GGAGAASAPTGTPSGQPLAVAPGLGSSPLV 337

Query: 400 LALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGG-----GLPPELPPRRGKPPP 454
            A      + P  +   P G L P      P     PAG      G P  LP +   P  
Sbjct: 338 PAPNVILHRTPTPIQPKPAGVLPPKLYQLTP-KPFAPAGATLTIQGEPGALPQQPKAPQN 396

Query: 455 LLPSVLGPAGGDREALGLGPPAAQLT----PPPAPVGLRGSGLRGLQKDSGPLPTPPGVS 510
           L     G AG +    G   PA Q      PP    G          +  G L  P  V 
Sbjct: 397 LTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTG------AAPPQPPGALSKPMSVH 450

Query: 511 LLGEP-----PKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPA 565
           LL +      P  + +P      L    PA  L  + +      G     A  P T    
Sbjct: 451 LLNQGSSIVIPAQHMLPGQNQFLLPG-APAVQLPQQLSALPANVGGQILAAAAPHT---- 505

Query: 566 PGGGSSSSKAFQLKSRLLSPLS-SARLPPEPGLSDSYSFD-YPSDMGPRRLFSHPREPAL 623
             GG   +        L  PLS    L P  G   ++     P  +G   LF  P   A 
Sbjct: 506 --GGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAA 563

Query: 624 G 624
           G
Sbjct: 564 G 564



 Score = 31.6 bits (70), Expect = 2.8
 Identities = 70/297 (23%), Positives = 101/297 (34%), Gaps = 40/297 (13%)

Query: 385  MPLLNGPALST--ALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLLGELPAGGGLP 442
            MP  N P + T  A  ++ L+ + +++ G+       AL P  QP              P
Sbjct: 1289 MPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPP-------------P 1335

Query: 443  PELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQL-----TPPPAP-VGLRGSGLRGL 496
            P    +  +PPP  P    P G     +   PPAA       T P  P + LR +    +
Sbjct: 1336 PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRLPLRKTYRENV 1395

Query: 497  QKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGWGGAGRSRRPA 556
                 P  TP G +  G P      PL   ++  +      LA  E   +      +R  
Sbjct: 1396 GGPGAPEGTPAGRARGGSP-----APLPAKVDEATSGLIRELAAVEDELY------QRML 1444

Query: 557  EGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSARLPPEPGLSD-SYSFDYPSDMGPRRLF 615
            +GPP  P A     +    ++       P +  R    P +   S+S D P D       
Sbjct: 1445 KGPPPEPAASAAQGTGDPDWEAPG---LPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501

Query: 616  SHPREPALG-PHGPSRHKMSPPPSGFGERSSGGSGGGPLSHFYSGSPTSYFTSGLQA 671
                +  L     P R   +P PS     S+G     P  H     P S    GL A
Sbjct: 1502 QSAIDSILNLQQAPGR---TPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLGA 1555


>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
           preproprotein [Homo sapiens]
          Length = 331

 Score = 56.6 bits (135), Expect = 8e-08
 Identities = 77/291 (26%), Positives = 99/291 (34%), Gaps = 52/291 (17%)

Query: 373 GGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGILGDSPLGALQPGAQPANPLL 432
           GG +     PP  P    P    +    +   + Q  P   G+ P G   P  +P  P  
Sbjct: 64  GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP-- 121

Query: 433 GELPAGGGLPPELPPRRGKP---------------PPLLPSVLGPAGGDREALGLGPPAA 477
              P  GG  P+ PP  GKP               PP  P    P GG++   G  PP  
Sbjct: 122 ---PPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQ-GPPPPPG 177

Query: 478 QLTPPPAPVGLRGSGLRGLQKDSGPLP---------TPPGVSLLGEPPKDYRIPLNPYLN 528
           +   PP   G +  G     K  GP P         +PPG    G PP+    P  P   
Sbjct: 178 KPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQ-GPPPQGGNQPQGPPP- 235

Query: 529 LHSLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSS 588
                P     G   +G  G      P  G P  PPA GG  S S          SP   
Sbjct: 236 -----PPGKPQGPPPQG--GNKPQGPPPPGKPQGPPAQGGSKSQSAR--------SPPGK 280

Query: 589 ARLPPEPGLSDSYSFDYPSDMGPRRLFSHPREPALG-PHGPSRHKMSPPPS 638
            + PP+   ++      P+   P++    P+ P  G P GP R      PS
Sbjct: 281 PQGPPQQEGNNPQGPPPPAGGNPQQ----PQAPPAGQPQGPPRPPQGGRPS 327



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 83/318 (26%), Positives = 101/318 (31%), Gaps = 47/318 (14%)

Query: 423 PGAQPANPLLGELPAGGGLPPELPPRRGKP--PPLLPSVLGPAGGDREALGLGPPAAQLT 480
           P     NP  G  P GG  P   PP  GKP  PP       P GG++   G  PP     
Sbjct: 29  PSLIAGNPQ-GPSPQGGNKPQGPPPPPGKPQGPP-------PQGGNKPQ-GPPPPGKPQG 79

Query: 481 PPP---------APVGL-RGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLH 530
           PPP         +P G  +G   +G  +  GP P PPG    G PP+    P  P     
Sbjct: 80  PPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGP-PPPPG-KPQGPPPQGGNRPQGP----- 132

Query: 531 SLLPASNLAGKEARGWGGAGRSRRPAEGPPTNPPAPGGGSSSSKAFQLKSRLLSPLSSAR 590
              P     G   +  G   RS R   G P  PP  GG                P    +
Sbjct: 133 --PPPGKPQGPPPQ--GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGK 188

Query: 591 LPPEPGLSDSYSFDYPSDMGPRRLFSHPREP----------ALGPHGPSRHKMSPPPSGF 640
            P  P          P     R   S P +P            GP  P      PPP G 
Sbjct: 189 KPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG- 247

Query: 641 GERSSG----GSGGGPLSHFYSGSPTSYFTSGLQAGLKQSHLSKAIGSSPLGSGEGLLGL 696
           G +  G    G   GP +   S S ++    G   G  Q   +   G  P   G      
Sbjct: 248 GNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQ 307

Query: 697 SPGPNGHSHLLKTPLGGQ 714
           +P         + P GG+
Sbjct: 308 APPAGQPQGPPRPPQGGR 325



 Score = 42.4 bits (98), Expect = 0.002
 Identities = 56/208 (26%), Positives = 67/208 (32%), Gaps = 50/208 (24%)

Query: 373 GGKQGLLGAPPAMPLLNGPALSTALLQLALQTQGQKKPGI------LGDSPLGALQPGAQ 426
           GG Q   G PP      GP       Q   + QG   PG        GD    +  P  +
Sbjct: 165 GGNQPQ-GPPPPPGKPQGPPP-----QGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK 218

Query: 427 PANPLLGELPAGGGLPPELPPRRGKPPPLLPSVLGPAGGDREALGLGPPAAQLTPPPAPV 486
           P  P     P  GG  P+ PP    PPP  P    P GG++     GPP     PP  P 
Sbjct: 219 PQGP-----PPQGGNQPQGPP----PPPGKPQGPPPQGGNKPQ---GPP-----PPGKPQ 261

Query: 487 GLRGSGLRGLQKDSGPLPTPPGVSLLGEPPKDYRIPLNPYLNLHSLLPASNLAGKEARGW 546
           G    G    Q    P   P G      PP+                  +N  G      
Sbjct: 262 GPPAQGGSKSQSARSPPGKPQG------PPQQ---------------EGNNPQGPPPPAG 300

Query: 547 GGAGRSRRPAEGPPTNPPAPGGGSSSSK 574
           G   + + P  G P  PP P  G   S+
Sbjct: 301 GNPQQPQAPPAGQPQGPPRPPQGGRPSR 328


>gi|49472822 eukaryotic translation initiation factor 3, subunit 4
           delta, 44kDa [Homo sapiens]
          Length = 320

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 28/77 (36%), Positives = 42/77 (54%)

Query: 148 DALLCVANLPPSLTQQQFEELVRPFGSLERCFLVYSERTGQSKGYGFAEYMKKDSAARAK 207
           +A + V NL     +   +EL RPFGS+ R +L   + TGQSKG+ F  + +++ AARA 
Sbjct: 238 NATIRVTNLSEDTRETDLQELFRPFGSISRIYLAKDKTTGQSKGFAFISFHRREDAARAI 297

Query: 208 SDLLGKPLGPRTLYVHW 224
           + + G       L V W
Sbjct: 298 AGVSGFGYDHLILNVEW 314


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.137    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,466,022
Number of Sequences: 37866
Number of extensions: 2722648
Number of successful extensions: 15218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 1175
Number of HSP's that attempted gapping in prelim test: 10659
Number of HSP's gapped (non-prelim): 4362
length of query: 756
length of database: 18,247,518
effective HSP length: 110
effective length of query: 646
effective length of database: 14,082,258
effective search space: 9097138668
effective search space used: 9097138668
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.