Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 31543806
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31543806 thrombospondin 4 precursor [Homo sapiens]
(961 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31543806 thrombospondin 4 precursor [Homo sapiens] 2030 0.0
gi|6005902 thrombospondin 3 precursor [Homo sapiens] 1224 0.0
gi|40217843 cartilage oligomeric matrix protein precursor [Homo ... 1133 0.0
gi|40317628 thrombospondin 2 precursor [Homo sapiens] 710 0.0
gi|40317626 thrombospondin 1 precursor [Homo sapiens] 692 0.0
gi|126091152 cubilin [Homo sapiens] 107 5e-23
gi|24430141 fibrillin 1 precursor [Homo sapiens] 100 1e-20
gi|118572606 hemicentin 1 [Homo sapiens] 99 2e-20
gi|110347437 latent transforming growth factor beta binding prot... 98 4e-20
gi|110347412 latent transforming growth factor beta binding prot... 98 4e-20
gi|110347431 latent transforming growth factor beta binding prot... 98 4e-20
gi|34734064 fibulin 1 isoform B precursor [Homo sapiens] 97 9e-20
gi|34734068 fibulin 1 isoform A precursor [Homo sapiens] 97 9e-20
gi|34734066 fibulin 1 isoform D [Homo sapiens] 97 9e-20
gi|34734062 fibulin 1 isoform C precursor [Homo sapiens] 97 9e-20
gi|112420992 crumbs homolog 2 [Homo sapiens] 94 6e-19
gi|134244285 Notch homolog 3 [Homo sapiens] 92 2e-18
gi|194328809 latent transforming growth factor beta binding prot... 92 2e-18
gi|18497288 latent transforming growth factor beta binding prote... 92 2e-18
gi|66346695 fibrillin 2 precursor [Homo sapiens] 91 4e-18
gi|46249414 latent transforming growth factor beta binding prote... 89 3e-17
gi|46249412 latent transforming growth factor beta binding prote... 89 3e-17
gi|61743978 stabilin 1 precursor [Homo sapiens] 88 4e-17
gi|24041035 notch 2 preproprotein [Homo sapiens] 87 7e-17
gi|110735443 delta-like 1 [Homo sapiens] 86 2e-16
gi|21704279 jagged 2 isoform b precursor [Homo sapiens] 86 2e-16
gi|148833508 notch1 preproprotein [Homo sapiens] 85 3e-16
gi|4557733 latent transforming growth factor beta binding protei... 84 6e-16
gi|21704277 jagged 2 isoform a precursor [Homo sapiens] 84 6e-16
gi|55770876 notch4 preproprotein [Homo sapiens] 84 6e-16
>gi|31543806 thrombospondin 4 precursor [Homo sapiens]
Length = 961
Score = 2030 bits (5260), Expect = 0.0
Identities = 961/961 (100%), Positives = 961/961 (100%)
Query: 1 MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV 60
MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV
Sbjct: 1 MLAPRGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDPALNDLYV 60
Query: 61 ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA 120
ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA
Sbjct: 61 ISTFKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLA 120
Query: 121 DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ 180
DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ
Sbjct: 121 DGRRHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQRKPQ 180
Query: 181 DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL 240
DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL
Sbjct: 181 DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGTGDFNRQFLGQMTQLNQLLGEVKDL 240
Query: 241 LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ 300
LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ
Sbjct: 241 LRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQ 300
Query: 301 CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP 360
CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP
Sbjct: 301 CTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP 360
Query: 361 MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA 420
MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA
Sbjct: 361 MVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKA 420
Query: 421 ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR 480
ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR
Sbjct: 421 ERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR 480
Query: 481 NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG 540
NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG
Sbjct: 481 NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFG 540
Query: 541 DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD 600
DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD
Sbjct: 541 DACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGD 600
Query: 601 ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG 660
ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG
Sbjct: 601 ACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIG 660
Query: 661 DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP 720
DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP
Sbjct: 661 DECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCP 720
Query: 721 ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD 780
ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD
Sbjct: 721 ENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVD 780
Query: 781 FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK 840
FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK
Sbjct: 781 FEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVK 840
Query: 841 SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE 900
SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE
Sbjct: 841 SKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYE 900
Query: 901 GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD 960
GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD
Sbjct: 901 GSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQTQNFDRFD 960
Query: 961 N 961
N
Sbjct: 961 N 961
>gi|6005902 thrombospondin 3 precursor [Homo sapiens]
Length = 956
Score = 1224 bits (3167), Expect = 0.0
Identities = 585/969 (60%), Positives = 703/969 (72%), Gaps = 44/969 (4%)
Query: 5 RGAAVLLLHLVLQRWLAAGAQATPQVFDLLPSSSQRLNPGALLPVLTDP-ALNDLYVIST 63
RGA LLL A QV DLL R + T D+Y++ST
Sbjct: 7 RGALALLLLCFF-----TSASQDLQVIDLLTVGESRQMVAVAEKIRTALLTAGDIYLLST 61
Query: 64 FKLQTKSSATIFGLYSSTDNSKYFEFTVMGRLNKAILRYLKNDGKVHLVVFNNLQLADGR 123
F+L K +FGLYS DN+++ E +V+G++NK ++RY + DGKVH V LADGR
Sbjct: 62 FRLPPKQGGVLFGLYSRQDNTRWLEASVVGKINKVLVRYQREDGKVHAVNLQQAGLADGR 121
Query: 124 RHRILLRLSNLQRGAGSLELYLDCIQVDSVHNLPRAFAGPSQKPETIELRTFQR---KPQ 180
H +LLRL R + +L LY+DC D LP P + + +E+RT Q+ + Q
Sbjct: 122 THTVLLRLRGPSRPSPALHLYVDCKLGDQHAGLPALAPIPPAEVDGLEIRTGQKAYLRMQ 181
Query: 181 DFLEELKLVVRGSLFQVASLQDCFLQQSEPLAATGT-------GDFNRQFLGQMTQLNQL 233
F+E +K+++ GS+ +V +L +C Q E + + T G+ + + Q+T NQ+
Sbjct: 182 GFVESMKIILGGSMARVGALSECPFQGDESIHSAVTNALHSILGEQTKALVTQLTLFNQI 241
Query: 234 LGEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSN 293
L E++D +R QVKE S +RNTI ECQ CG + +S C N
Sbjct: 242 LVELRDDIRDQVKEMSLIRNTIMECQVCGFHEQRS--------------------HCSPN 281
Query: 294 PCFRGVQCTDSRD--GFQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINLSPGFRC 350
PCFRGV C + + G++CGPCP G GNG C D++EC + PC+PG CIN PGF C
Sbjct: 282 PCFRGVDCMEVYEYPGYRCGPCPPGLQGNGTHCSDINECAHADPCFPGSSCINTMPGFHC 341
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR---NGACVPNSICVNTLGSYRCGPCK 407
+ACP G+ G V GVGI +A+++KQVC DIDEC NG C PNSIC NT+GS++CGPC+
Sbjct: 342 EACPRGYKGTQVSGVGIDYARASKQVCNDIDECNDGNNGGCDPNSICTNTVGSFKCGPCR 401
Query: 408 PGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDI 467
G+ G+Q +GC R C +P +PC ++A C+ ER G V+C C VGWAG+G +CG D DI
Sbjct: 402 LGFLGNQSQGCLPARTCHSPAHSPCHIHAHCLFERNGAVSCQCNVGWAGNGNVCGTDTDI 461
Query: 468 DSYPDEELPCSARN--CKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL 525
D YPD+ LPC N CK+DNC PNSGQEDAD DG+GD CD+DADGDGI N +DNC L
Sbjct: 462 DGYPDQALPCMDNNKHCKQDNCLLTPNSGQEDADNDGVGDQCDDDADGDGIKNVEDNCRL 521
Query: 526 IHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF 585
N DQ+NSD D FGDACDNC +V NNDQKDTDG+G GDACD+D+DGDGI N LDNCPK
Sbjct: 522 FPNKDQQNSDTDSFGDACDNCPNVPNNDQKDTDGNGEGDACDNDVDGDGIPNGLDNCPKV 581
Query: 586 PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPT 645
PN Q D+D DGVGDACDSCP++SNP Q+D D+DLVGD CDTN+DSDGDGHQD+ DNCP
Sbjct: 582 PNPLQTDRDEDGVGDACDSCPEMSNPTQTDADSDLVGDVCDTNEDSDGDGHQDTKDNCPQ 641
Query: 646 VINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNPAQEDSNSDGVGDICES 705
+ NS+QLD+D DG+GDECD DDDNDGIPD VPPGPDNCRLVPNP Q+DS+ +GVGD+CE
Sbjct: 642 LPNSSQLDSDNDGLGDECDGDDDNDGIPDYVPPGPDNCRLVPNPNQKDSDGNGVGDVCED 701
Query: 706 DFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS 765
DFD D V+D +DVCPE+AEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS
Sbjct: 702 DFDNDAVVDPLDVCPESAEVTLTDFRAYQTVVLDPEGDAQIDPNWVVLNQGMEIVQTMNS 761
Query: 766 DPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFYVVMWKQTEQTYWQATP 825
DPGLAVGYTAFNGVDFEGTFHVNT TDDDYAGF+F YQDS FYVVMWKQTEQTYWQATP
Sbjct: 762 DPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFLFSYQDSGRFYVVMWKQTEQTYWQATP 821
Query: 826 FRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKDSRNVGWKDKVSYRWFL 885
FRAVA+PG+QLKAV S +GPGEHLRN+LWHTG T DQVRLLW D RNVGW+DK SYRW L
Sbjct: 822 FRAVAQPGLQLKAVTSVSGPGEHLRNALWHTGHTPDQVRLLWTDPRNVGWRDKTSYRWQL 881
Query: 886 QHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQENIIWSNLKYRCNDTIP 945
HRPQVGYIRV+ YEG +LVADSGV IDT+MRGGRLGVFCFSQENIIWSNL+YRCNDT+P
Sbjct: 882 LHRPQVGYIRVKLYEGPQLVADSGVIIDTSMRGGRLGVFCFSQENIIWSNLQYRCNDTVP 941
Query: 946 EDFQEFQTQ 954
EDF+ F+ Q
Sbjct: 942 EDFEPFRRQ 950
>gi|40217843 cartilage oligomeric matrix protein precursor [Homo
sapiens]
Length = 757
Score = 1133 bits (2930), Expect = 0.0
Identities = 521/752 (69%), Positives = 601/752 (79%), Gaps = 24/752 (3%)
Query: 211 LAATGTG------DFNRQFLGQMTQLNQLLGEVKDLLRQQVKETSFLRNTIAECQACGPL 264
L A+G G D Q L ++ + N L +V++LLRQQV+E +FL+NT+ EC ACG
Sbjct: 16 LGASGQGQSPLGSDLGPQMLRELQETNAALQDVRELLRQQVREITFLKNTVMECDACG-- 73
Query: 265 KFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC 324
Q + + P RP C CF GV C + G +CGPCP G+TGNG C
Sbjct: 74 -MQQSVRTGL-------PSVRPLLHCAPGFCFPGVACIQTESGARCGPCPAGFTGNGSHC 125
Query: 325 IDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR 384
DV+EC HPC+P V CIN SPGFRC+ACP G++GP QGVG++FAK+NKQVCTDI+EC
Sbjct: 126 TDVNECNAHPCFPRVRCINTSPGFRCEACPPGYSGPTHQGVGLAFAKANKQVCTDINECE 185
Query: 385 NGA--CVPNSICVNTLGSYRCGPCKPGYTGDQIRGC--KAERNCRNPELNPCSVNAQCIE 440
G CVPNS+C+NT GS++CGPC+PG+ GDQ GC +A+R C + + C +A C+
Sbjct: 186 TGQHNCVPNSVCINTRGSFQCGPCQPGFVGDQASGCQRRAQRFCPDGSPSECHEHADCVL 245
Query: 441 ERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR 500
ER G +CVC VGWAG+G +CG+D D+D +PDE+L C R C+KDNC VPNSGQED DR
Sbjct: 246 ERDGSRSCVCAVGWAGNGILCGRDTDLDGFPDEKLRCPERQCRKDNCVTVPNSGQEDVDR 305
Query: 501 DGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGD 560
DGIGDACD DADGDG+ NE+DNC L+ N DQRN+D+D +GDACDNC S N+DQKDTD D
Sbjct: 306 DGIGDACDPDADGDGVPNEKDNCPLVRNPDQRNTDEDKWGDACDNCRSQKNDDQKDTDQD 365
Query: 561 GRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDL 620
GRGDACDDD+DGD I+N DNCP+ PN DQ+D DGDG+GDACD+CP SNP+Q+DVD+D
Sbjct: 366 GRGDACDDDIDGDRIRNQADNCPRVPNSDQKDSDGDGIGDACDNCPQKSNPDQADVDHDF 425
Query: 621 VGDSCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGP 680
VGD+CD++QD DGDGHQDS DNCPTV NSAQ D+D DG GD CDDDDDNDG+PD
Sbjct: 426 VGDACDSDQDQDGDGHQDSRDNCPTVPNSAQEDSDHDGQGDACDDDDDNDGVPD----SR 481
Query: 681 DNCRLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDP 740
DNCRLVPNP QED++ DGVGD+C+ DFD D+V+D+IDVCPENAEVTLTDFRA+QTVVLDP
Sbjct: 482 DNCRLVPNPGQEDADRDGVGDVCQDDFDADKVVDKIDVCPENAEVTLTDFRAFQTVVLDP 541
Query: 741 EGDAQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIF 800
EGDAQIDPNWVVLNQG EIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNT TDDDYAGFIF
Sbjct: 542 EGDAQIDPNWVVLNQGREIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTVTDDDYAGFIF 601
Query: 801 GYQDSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTS 860
GYQDSSSFYVVMWKQ EQTYWQA PFRAVAEPGIQLKAVKS TGPGE LRN+LWHTGDT
Sbjct: 602 GYQDSSSFYVVMWKQMEQTYWQANPFRAVAEPGIQLKAVKSSTGPGEQLRNALWHTGDTE 661
Query: 861 DQVRLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGR 920
QVRLLWKD RNVGWKDK SYRWFLQHRPQVGYIRVRFYEG ELVADS V +DTTMRGGR
Sbjct: 662 SQVRLLWKDPRNVGWKDKKSYRWFLQHRPQVGYIRVRFYEGPELVADSNVVLDTTMRGGR 721
Query: 921 LGVFCFSQENIIWSNLKYRCNDTIPEDFQEFQ 952
LGVFCFSQENIIW+NL+YRCNDTIPED++ Q
Sbjct: 722 LGVFCFSQENIIWANLRYRCNDTIPEDYETHQ 753
>gi|40317628 thrombospondin 2 precursor [Homo sapiens]
Length = 1172
Score = 710 bits (1832), Expect = 0.0
Identities = 352/673 (52%), Positives = 426/673 (63%), Gaps = 66/673 (9%)
Query: 286 PPRRCDSNPCFRGVQCTDSRDG-FQCGPCPEGYTGNGITCIDVDECKYHP--CYPG---V 339
P C SNPCF G QC+ DG + CG CP G+ GNG C D+DEC P C+
Sbjct: 549 PVDGCLSNPCFPGAQCSSFPDGSWSCGSCPVGFLGNGTHCEDLDECALVPDICFSTSKVP 608
Query: 340 HCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNT 397
C+N PGF C CP + G GVG+ AK+ KQVC + C++ C ++ C+
Sbjct: 609 RCVNTQPGFHCLPCPPRYRGNQPVGVGLEAAKTEKQVCEPENPCKDKTHNCHKHAECI-Y 667
Query: 398 LG-----SYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGV 452
LG Y+C C+ GY GD
Sbjct: 668 LGHFSDPMYKC-ECQTGYAGD--------------------------------------- 687
Query: 453 GWAGDGYICGKDVDIDSYPDEELPCSAR---NCKKDNCKYVPNSGQEDADRDGIGDACDE 509
G ICG+D D+D +P+ L C+ +C KDNC ++PNSGQED D+DGIGDACD+
Sbjct: 688 -----GLICGEDSDLDGWPNLNLVCATNATYHCIKDNCPHLPNSGQEDFDKDGIGDACDD 742
Query: 510 DADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDD 569
D D DG+ +E+DNC L+ N Q + DKD GD CDNC V N Q DTD +G GDAC D
Sbjct: 743 DDDNDGVTDEKDNCQLLFNPRQADYDKDEVGDRCDNCPYVHNPAQIDTDNNGEGDACSVD 802
Query: 570 MDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGDSCDTNQ 629
+DGD + N DNCP N DQRD DGDGVGD CD+CP V NP+Q+DVDNDLVGD CD N+
Sbjct: 803 IDGDDVFNERDNCPYVYNTDQRDTDGDGVGDHCDNCPLVHNPDQTDVDNDLVGDQCDNNE 862
Query: 630 DSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNCRLVPNP 689
D D DGHQ++ DNCP + N+ Q D D+DG GD CD DDDNDG+PD DNCRLV NP
Sbjct: 863 DIDDDGHQNNQDNCPYISNANQADHDRDGQGDACDPDDDNDGVPD----DRDNCRLVFNP 918
Query: 690 AQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGDAQIDPN 749
QED + DG GDIC+ DFD D + D DVCPEN ++ TDFR +Q V LDP+G QIDPN
Sbjct: 919 DQEDLDGDGRGDICKDDFDNDNIPDIDDVCPENNAISETDFRNFQMVPLDPKGTTQIDPN 978
Query: 750 WVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQDSSSFY 809
WV+ +QG E+VQT NSDPG+AVG+ F VDF GTF+VNT DDDYAGF+FGYQ SS FY
Sbjct: 979 WVIRHQGKELVQTANSDPGIAVGFDEFGSVDFSGTFYVNTDRDDDYAGFVFGYQSSSRFY 1038
Query: 810 VVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQVRLLWKD 869
VVMWKQ QTYW+ P RA G+ LK V S TG GEHLRN+LWHTG+T QVR LW D
Sbjct: 1039 VVMWKQVTQTYWEDQPTRAYGYSGVSLKVVNSTTGTGEHLRNALWHTGNTPGQVRTLWHD 1098
Query: 870 SRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGVFCFSQE 929
RN+GWKD +YRW L HRP+ GYIRV +EG +++ADSG D T GGRLG+F FSQE
Sbjct: 1099 PRNIGWKDYTAYRWHLTHRPKTGYIRVLVHEGKQVMADSGPIYDQTYAGGRLGLFVFSQE 1158
Query: 930 NIIWSNLKYRCND 942
+ +S+LKY C D
Sbjct: 1159 MVYFSDLKYECRD 1171
>gi|40317626 thrombospondin 1 precursor [Homo sapiens]
Length = 1170
Score = 692 bits (1787), Expect = 0.0
Identities = 350/679 (51%), Positives = 430/679 (63%), Gaps = 50/679 (7%)
Query: 288 RRCDS-NPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSP 346
R C++ P F G C G E N C +D C +PC+ GV C +
Sbjct: 517 RLCNNPTPQFGGKDCV--------GDVTENQICNKQDC-PIDGCLSNPCFAGVKCTSYPD 567
Query: 347 G-FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNS---ICVNTLGS 400
G ++C ACP G++G +Q CTD+DEC+ AC ++ C NT
Sbjct: 568 GSWKCGACPPGYSGNGIQ-------------CTDVDECKEVPDACFNHNGEHRCENTDPG 614
Query: 401 YRCGPCKPGYTGDQIRGCKAERNCRNPEL----NPCS-------VNAQCI---EERQGDV 446
Y C PC P +TG Q G E N ++ NPC+ NA+C
Sbjct: 615 YNCLPCPPRFTGSQPFGQGVEHATANKQVCKPRNPCTDGTHDCNKNAKCNYLGHYSDPMY 674
Query: 447 TCVCGVGWAGDGYICGKDVDIDSYPDEELPCSAR---NCKKDNCKYVPNSGQEDADRDGI 503
C C G+AG+G ICG+D D+D +P+E L C A +CKKDNC +PNSGQED D+DGI
Sbjct: 675 RCECKPGYAGNGIICGEDTDLDGWPNENLVCVANATYHCKKDNCPNLPNSGQEDYDKDGI 734
Query: 504 GDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRG 563
GDACD+D D D I +++DNC +N Q + D+D GD CDNC N DQ DTD +G G
Sbjct: 735 GDACDDDDDNDKIPDDRDNCPFHYNPAQYDYDRDDVGDRCDNCPYNHNPDQADTDNNGEG 794
Query: 564 DACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLVGD 623
DAC D+DGDGI N DNC N DQRD D DGVGD CD+CP NP+Q D D+D +GD
Sbjct: 795 DACAADIDGDGILNERDNCQYVYNVDQRDTDMDGVGDQCDNCPLEHNPDQLDSDSDRIGD 854
Query: 624 SCDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPGPDNC 683
+CD NQD D DGHQ++ DNCP V N+ Q D DKDG GD CD DDDNDGIPD DNC
Sbjct: 855 TCDNNQDIDEDGHQNNLDNCPYVPNANQADHDKDGKGDACDHDDDNDGIPD----DKDNC 910
Query: 684 RLVPNPAQEDSNSDGVGDICESDFDQDQVIDRIDVCPENAEVTLTDFRAYQTVVLDPEGD 743
RLVPNP Q+DS+ DG GD C+ DFD D V D D+CPEN +++ TDFR +Q + LDP+G
Sbjct: 911 RLVPNPDQKDSDGDGRGDACKDDFDHDSVPDIDDICPENVDISETDFRRFQMIPLDPKGT 970
Query: 744 AQIDPNWVVLNQGMEIVQTMNSDPGLAVGYTAFNGVDFEGTFHVNTQTDDDYAGFIFGYQ 803
+Q DPNWVV +QG E+VQT+N DPGLAVGY FN VDF GTF +NT+ DDDYAGF+FGYQ
Sbjct: 971 SQNDPNWVVRHQGKELVQTVNCDPGLAVGYDEFNAVDFSGTFFINTERDDDYAGFVFGYQ 1030
Query: 804 DSSSFYVVMWKQTEQTYWQATPFRAVAEPGIQLKAVKSKTGPGEHLRNSLWHTGDTSDQV 863
SS FYVVMWKQ Q+YW P RA G+ +K V S TGPGEHLRN+LWHTG+T QV
Sbjct: 1031 SSSRFYVVMWKQVTQSYWDTNPTRAQGYSGLSVKVVNSTTGPGEHLRNALWHTGNTPGQV 1090
Query: 864 RLLWKDSRNVGWKDKVSYRWFLQHRPQVGYIRVRFYEGSELVADSGVTIDTTMRGGRLGV 923
R LW D R++GWKD +YRW L HRP+ G+IRV YEG +++ADSG D T GGRLG+
Sbjct: 1091 RTLWHDPRHIGWKDFTAYRWRLSHRPKTGFIRVVMYEGKKIMADSGPIYDKTYAGGRLGL 1150
Query: 924 FCFSQENIIWSNLKYRCND 942
F FSQE + +S+LKY C D
Sbjct: 1151 FVFSQEMVFFSDLKYECRD 1169
>gi|126091152 cubilin [Homo sapiens]
Length = 3623
Score = 107 bits (267), Expect = 5e-23
Identities = 75/231 (32%), Positives = 100/231 (43%), Gaps = 41/231 (17%)
Query: 235 GEVKDLLRQQVKETSFLRNTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNP 294
G +DL+R+Q E + C F P +P R P
Sbjct: 228 GICEDLMREQAGEPKY------SCVCDAGWMFS--------PNSPACTLDRDECSFQPGP 273
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYH----PCYPGVHCINLSPGFRC 350
C VQC +++ F CG CP G+ GNG C D++EC+ + P V C+N C
Sbjct: 274 CSTLVQCFNTQGSFYCGACPTGWQGNGYICEDINECEINNGGCSVAPPVECVNTPGSSHC 333
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGACVPNSICVNTLGSYRCGPCKP 408
ACP G+ G + +VCT D C NG C P++ C +TLGS C P
Sbjct: 334 QACPPGYQG-------------DGRVCTLTDICSVSNGGCHPDASCSSTLGSLPLCTCLP 380
Query: 409 GYTGDQI--RGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
GYTG+ GC N C + +PC +N QCI+ G C C GW G
Sbjct: 381 GYTGNGYGPNGCVQLSNICLS---HPC-LNGQCIDTVSG-YFCKCDSGWTG 426
Score = 80.1 bits (196), Expect = 9e-15
Identities = 53/150 (35%), Positives = 64/150 (42%), Gaps = 22/150 (14%)
Query: 317 YTGNGITC-IDVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN 373
++ N C +D DEC + P C V C N F C ACP G+ G N
Sbjct: 253 FSPNSPACTLDRDECSFQPGPCSTLVQCFNTQGSFYCGACPTGWQG-------------N 299
Query: 374 KQVCTDIDECR--NGAC--VPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPEL 429
+C DI+EC NG C P CVNT GS C C PGY GD R C C +
Sbjct: 300 GYICEDINECEINNGGCSVAPPVECVNTPGSSHCQACPPGYQGDG-RVCTLTDIC-SVSN 357
Query: 430 NPCSVNAQCIEERQGDVTCVCGVGWAGDGY 459
C +A C C C G+ G+GY
Sbjct: 358 GGCHPDASCSSTLGSLPLCTCLPGYTGNGY 387
Score = 69.7 bits (169), Expect = 1e-11
Identities = 57/183 (31%), Positives = 74/183 (40%), Gaps = 26/183 (14%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP-----CYPGVHCINL 344
C SNPC G C + D F C CP + G + DV+EC+ + C G C+N
Sbjct: 136 CSSNPCQNGGTCLNLHDSFFC-ICPPQWKGP-LCSADVNECEIYSGTPLSCQNGGTCVNT 193
Query: 345 SPGFRCDACPVGFTGPMVQGV-----GISFAKSNKQVCTDIDECRNGACVPNSICVNTLG 399
+ C CP GP G S A+ +C D+ R A P CV G
Sbjct: 194 MGSYSCH-CPPETYGPQCASKYDDCEGGSVARCVHGICEDL--MREQAGEPKYSCVCDAG 250
Query: 400 SYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTC-VCGVGWAGDG 458
+ P P C +R+ + + PCS QC QG C C GW G+G
Sbjct: 251 -WMFSPNSPA--------CTLDRDECSFQPGPCSTLVQCFNT-QGSFYCGACPTGWQGNG 300
Query: 459 YIC 461
YIC
Sbjct: 301 YIC 303
Score = 48.9 bits (115), Expect = 2e-05
Identities = 36/123 (29%), Positives = 51/123 (41%), Gaps = 23/123 (18%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGIT---CIDVDE-CKYHPCYPGVHCINLSPGFRC 350
C C+ + C GYTGNG C+ + C HPC G CI+ G+ C
Sbjct: 360 CHPDASCSSTLGSLPLCTCLPGYTGNGYGPNGCVQLSNICLSHPCLNG-QCIDTVSGYFC 418
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTD-IDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C G+TG CT+ I+EC + C+ CV+ + S+ C C
Sbjct: 419 K-CDSGWTGVN---------------CTENINECLSNPCLNGGTCVDGVDSFSC-ECTRL 461
Query: 410 YTG 412
+TG
Sbjct: 462 WTG 464
Score = 47.4 bits (111), Expect = 7e-05
Identities = 27/75 (36%), Positives = 41/75 (54%), Gaps = 6/75 (8%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINLSPGF 348
C S+PC G QC D+ G+ C C G+TG + C + ++EC +PC G C++ F
Sbjct: 399 CLSHPCLNG-QCIDTVSGYFC-KCDSGWTG--VNCTENINECLSNPCLNGGTCVDGVDSF 454
Query: 349 RCDACPVGFTGPMVQ 363
C+ C +TG + Q
Sbjct: 455 SCE-CTRLWTGALCQ 468
>gi|24430141 fibrillin 1 precursor [Homo sapiens]
Length = 2871
Score = 99.8 bits (247), Expect = 1e-20
Identities = 74/231 (32%), Positives = 108/231 (46%), Gaps = 37/231 (16%)
Query: 290 CDSNPCF-RGVQCTDSRDGFQCGPCPEGYTGNGI--TCIDVDECKYHP--CYPGVHCINL 344
C+ NP G QCT+ ++C C +G+ + TC+DV+EC +P C G C N
Sbjct: 1242 CEDNPNICDGGQCTNIPGEYRC-LCYDGFMASEDMKTCVDVNECDLNPNICLSGT-CENT 1299
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGSYR 402
F C C +G++G K K CTDI+EC GA C +++C NT GS++
Sbjct: 1300 KGSFICH-CDMGYSG-----------KKGKTGCTDINECEIGAHNCGKHAVCTNTAGSFK 1347
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
C C PG+ GD I+ C C N + CS +A C + G C+C G+ GDG+ C
Sbjct: 1348 CS-CSPGWIGDGIK-CTDLDECSN-GTHMCSQHADC-KNTMGSYRCLCKEGYTGDGFTC- 1402
Query: 463 KDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGI----GDACDE 509
D+D E + C C P + + D + G AC++
Sbjct: 1403 --TDLD-----ECSENLNLCGNGQCLNAPGGYRCECDMGFVPSADGKACED 1446
Score = 84.0 bits (206), Expect = 6e-16
Identities = 108/429 (25%), Positives = 159/429 (37%), Gaps = 89/429 (20%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNG--ITCIDVDECKYHP-CYPGVHCINLSPGFRCD 351
C GV C + F+C CP G+ N + C D+DEC+ P C CIN + +RCD
Sbjct: 1777 CENGV-CINMVGSFRC-ECPVGFFYNDKLLVCEDIDECQNGPVCQRNAECINTAGSYRCD 1834
Query: 352 ACPVGFT----------------------GPMVQGVGISF--------AKSNKQVCTDID 381
C G+ G + VG + ++ +C DI+
Sbjct: 1835 -CKPGYRFTSTGQCNDRNECQEIPNICSHGQCIDTVGSFYCLCHTGFKTNDDQTMCLDIN 1893
Query: 382 ECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEE 441
EC AC N C NT+GS+ C C G+ C C + N C N QCI
Sbjct: 1894 ECERDAC-GNGTCRNTIGSFNC-RCNHGFILSHNNDCIDVDECASGNGNLCR-NGQCI-N 1949
Query: 442 RQGDVTCVCGVGW--AGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDAD 499
G C C G+ A DG C VDI+ E R C C+ + S
Sbjct: 1950 TVGSFQCQCNEGYEVAPDGRTC---VDIN-----ECLLEPRKCAPGTCQNLDGS-YRCIC 2000
Query: 500 RDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDG 559
G ++ D D + E + C L ++ + F C S+ ++ ++
Sbjct: 2001 PPGYSLQNEKCEDIDECVEEPEICAL----GTCSNTEGSFKCLCPEGFSLSSSGRRCQ-- 2054
Query: 560 DGRGDACDDDMDGDGIKNILDNCPKFPNRDQRD----KDGDGVGDACDSCPD-------- 607
D R C +G + PK N +++ G+G GD C+ CP
Sbjct: 2055 DLRMSYCYAKFEGGKCSS-----PKSRNHSKQECCCALKGEGWGDPCELCPTEPDEAFRQ 2109
Query: 608 --------VSNPNQSDVDND--LVGDSCDTNQDSDGDGHQDSTDNCP---TVINSAQLDT 654
+ P+ S VD D D C Q + DG CP + + +DT
Sbjct: 2110 ICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRC--ECPFGYILAGNECVDT 2167
Query: 655 DKDGIGDEC 663
D+ +G+ C
Sbjct: 2168 DECSVGNPC 2176
Score = 78.2 bits (191), Expect = 3e-14
Identities = 58/177 (32%), Positives = 78/177 (44%), Gaps = 23/177 (12%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVHCINLSPGFRCDACPVGFT 358
QC ++ ++C CP GY G C+D DEC +PC G C N+ GF C C GF
Sbjct: 2141 QCINTDGSYRC-ECPFGYILAGNECVDTDECSVGNPCGNGT-CKNVIGGFEC-TCEEGFE 2197
Query: 359 -GPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYT-GDQIR 416
GPM+ C DI+EC + CVNT GSY C C GY + R
Sbjct: 2198 PGPMM-------------TCEDINECAQNPLLCAFRCVNTYGSYEC-KCPVGYVLREDRR 2243
Query: 417 GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYICGKDVDIDSYP 471
CK E C + + C+ + G C+CG G+ DG C + + + P
Sbjct: 2244 MCKDEDECEEGK-HDCTEKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENECQTKP 2299
Score = 75.5 bits (184), Expect = 2e-13
Identities = 87/317 (27%), Positives = 119/317 (37%), Gaps = 61/317 (19%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDEC--KYHPCYPGVHCINLSPGFRCDA 352
C + C ++ ++C C EGYTG+G TC D+DEC + C G C+N G+RC+
Sbjct: 1374 CSQHADCKNTMGSYRC-LCKEGYTGDGFTCTDLDECSENLNLCGNG-QCLNAPGGYRCE- 1430
Query: 353 CPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTG 412
C +GF P G + C DIDEC C N G +RC C+ GY
Sbjct: 1431 CDMGFV-PSADG----------KACEDIDECSLPNICVFGTCHNLPGLFRC-ECEIGYEL 1478
Query: 413 DQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPD 472
D+ G NC ++N C CI CV G YIC D PD
Sbjct: 1479 DRSGG-----NC--TDVNECLDPTTCISG-----NCVNTPG----SYIC------DCPPD 1516
Query: 473 EELPCSARNC---KKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHNV 529
EL + C + NC + R GD + G G+ C L
Sbjct: 1517 FELNPTRVGCVDTRSGNCYL------DIRPRGDNGDTACSNEIGVGVSKASCCCSL---- 1566
Query: 530 DQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRD 589
+G C+ C +V ++ K G G + I +D C + P
Sbjct: 1567 ------GKAWGTPCEMCPAVNTSEYKILCPGGEGFRPNPI---TVILEDIDECQELPGLC 1617
Query: 590 QRDKDGDGVGDACDSCP 606
Q K + G CP
Sbjct: 1618 QGGKCINTFGSFQCRCP 1634
Score = 74.3 bits (181), Expect = 5e-13
Identities = 67/208 (32%), Positives = 89/208 (42%), Gaps = 42/208 (20%)
Query: 289 RCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGI---TCIDVDECKYHP--CYPGVHCIN 343
R + C RG QC ++ F+C C EGY + C+D+DEC+ P C GV C N
Sbjct: 1075 RISPDLCGRG-QCVNTPGDFEC-KCDEGYESGFMMMKNCMDIDECQRDPLLCRGGV-CHN 1131
Query: 344 LSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACV-PNSICVNTLGSYR 402
+RC+ CP G N C DI+EC A + PN CVN +G Y+
Sbjct: 1132 TEGSYRCE-CPPGHQ-----------LSPNISACIDINECELSAHLCPNGRCVNLIGKYQ 1179
Query: 403 CGPCKPGY--TGDQIRGCKAERNCRNPELNPCSV-NAQC---IEERQGDVTCVCGVGWA- 455
C C PGY T D++ C +++ CS+ N C +G C C G+A
Sbjct: 1180 CA-CNPGYHSTPDRL-FC--------VDIDECSIMNGGCETFCTNSEGSYECSCQPGFAL 1229
Query: 456 -GDGYICGKDVDIDSYPDEELPCSARNC 482
D C DID D C C
Sbjct: 1230 MPDQRSC---TDIDECEDNPNICDGGQC 1254
Score = 73.2 bits (178), Expect = 1e-12
Identities = 70/234 (29%), Positives = 97/234 (41%), Gaps = 54/234 (23%)
Query: 262 GPLKFQSPTPSTVVP------PAPPA----PPTRPPRRCDSNP----------CFRGVQC 301
GP+ P P P P PP P PPR N C G +C
Sbjct: 407 GPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNG-RC 465
Query: 302 TDSRDGFQCGPCPEGYTGN-GITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGP 360
+ +C C +G+ + CIDVDEC+ +PC G CIN + C C G+
Sbjct: 466 IPTPGSCRC-ECNKGFQLDLRGECIDVDECEKNPC-AGGECINNQGSYTCQ-CRAGYQST 522
Query: 361 MVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCK 419
+ + C DIDEC +NG N C+NT GS+ C C G+ +
Sbjct: 523 L-----------TRTECRDIDECLQNGRICNNGRCINTDGSFHC-VCNAGF-----HVTR 565
Query: 420 AERNCRNPELNPCSV-----NAQCIEERQGDVTCVCGVGW--AGDGYICGKDVD 466
+NC +++ CS+ N CI E G C+C G+ A DG C KD++
Sbjct: 566 DGKNCE--DMDECSIRNMCLNGMCINE-DGSFKCICKPGFQLASDGRYC-KDIN 615
Score = 70.5 bits (171), Expect = 7e-12
Identities = 58/200 (29%), Positives = 80/200 (40%), Gaps = 26/200 (13%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECK--YHPCYPGVHCINLSPGFRCDA 352
C + CT++ F+C C G+ G+GI C D+DEC H C C N +RC
Sbjct: 1333 CGKHAVCTNTAGSFKCS-CSPGWIGDGIKCTDLDECSNGTHMCSQHADCKNTMGSYRC-L 1390
Query: 353 CPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPCKPGYT 411
C G+TG + CTD+DEC N N C+N G YRC C G+
Sbjct: 1391 CKEGYTG-------------DGFTCTDLDECSENLNLCGNGQCLNAPGGYRC-ECDMGFV 1436
Query: 412 -GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSY 470
+ C+ C P + V C G C C +G+ D G D++
Sbjct: 1437 PSADGKACEDIDECSLPNI---CVFGTC-HNLPGLFRCECEIGYELD-RSGGNCTDVNEC 1491
Query: 471 PDEELPCSARNCKKDNCKYV 490
D C + NC Y+
Sbjct: 1492 LD-PTTCISGNCVNTPGSYI 1510
Score = 67.0 bits (162), Expect = 8e-11
Identities = 58/195 (29%), Positives = 76/195 (38%), Gaps = 28/195 (14%)
Query: 293 NPCFRGVQCTDSRDGFQCGPCPEGYTGNG--ITCIDVDECKYHPCYPGVHCINLSPGFRC 350
N C G QC D+ F C C G+ N C+D++EC+ C G C N F C
Sbjct: 1858 NICSHG-QCIDTVGSFYC-LCHTGFKTNDDQTMCLDINECERDACGNGT-CRNTIGSFNC 1914
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVNTLGSYRCGPCKP 408
C GF S+ C D+DEC NG N C+NT+GS++C C
Sbjct: 1915 -RCNHGFI------------LSHNNDCIDVDECASGNGNLCRNGQCINTVGSFQC-QCNE 1960
Query: 409 GY-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDI 467
GY R C C L P + G C+C G++ C DI
Sbjct: 1961 GYEVAPDGRTCVDINECL---LEPRKCAPGTCQNLDGSYRCICPPGYSLQNEKC---EDI 2014
Query: 468 DSYPDEELPCSARNC 482
D +E C+ C
Sbjct: 2015 DECVEEPEICALGTC 2029
Score = 65.9 bits (159), Expect = 2e-10
Identities = 52/168 (30%), Positives = 76/168 (45%), Gaps = 24/168 (14%)
Query: 291 DSNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDECK-YHPCYPGVHCINLSPG 347
D N C C ++ F C C G++ G +C DVDEC+ H C G C N+ G
Sbjct: 2531 DINLCGSKGICQNTPGSFTC-ECQRGFSLDQTGSSCEDVDECEGNHRCQHG--CQNIIGG 2587
Query: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCK 407
+RC +CP G+ + + N+ C D +EC + + C NTLGSY+C C
Sbjct: 2588 YRC-SCPQGY---------LQHYQWNQ--CVDENECLSAHICGGASCHNTLGSYKC-MCP 2634
Query: 408 PGYTGDQIR-GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
G+ +Q GC+ C + + PCS +G C C G+
Sbjct: 2635 AGFQYEQFSGGCQDINECGSAQA-PCSYGC---SNTEGGYLCGCPPGY 2678
Score = 60.8 bits (146), Expect = 6e-09
Identities = 68/224 (30%), Positives = 88/224 (39%), Gaps = 37/224 (16%)
Query: 300 QCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKY-HPCYPGVHCINLSPGFRCDACPVG 356
+C ++ F C C G+ T +G C D+DEC + C G+ CIN F+C C G
Sbjct: 545 RCINTDGSFHC-VCNAGFHVTRDGKNCEDMDECSIRNMCLNGM-CINEDGSFKC-ICKPG 601
Query: 357 FTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGY-TGDQI 415
F S+ + C DI+EC N CVNT GSYRC C PG G
Sbjct: 602 FQ-----------LASDGRYCKDINECETPGICMNGRCVNTDGSYRC-ECFPGLAVGLDG 649
Query: 416 RGCKAERNCRNPELNPCSVNAQCIEERQGDVT---CVCGVGWAGDGYICGKDVDIDSYPD 472
R C + + R+ QCI+ G VT C C A Y G+
Sbjct: 650 RVC-VDTHMRSTCYGGYK-RGQCIKPLFGAVTKSECCC----ASTEYAFGEPCQ------ 697
Query: 473 EELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGI 516
PC A+N + G A D A D D +GI
Sbjct: 698 ---PCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDICPNGI 738
Score = 60.1 bits (144), Expect = 1e-08
Identities = 66/253 (26%), Positives = 92/253 (36%), Gaps = 49/253 (19%)
Query: 293 NPCFRGVQCTDSRDGF--QCGPCP--------------EGYTGNGITCIDVDECKY-HPC 335
NP + C D G+ C CP G+ NG D+DECK H
Sbjct: 2356 NPVTKSECCCDGGRGWGPHCEICPFQGTVAFKKLCPHGRGFMTNGA---DIDECKVIHDV 2412
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICV 395
C+N + C C G+T P + G C D++EC N IC
Sbjct: 2413 CRNGECVNDRGSYHC-ICKTGYT-PDITGTS----------CVDLNECNQAPKPCNFICK 2460
Query: 396 NTLGSYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
NT GSY+C C GY + R CK C + N + I G TC C G+
Sbjct: 2461 NTEGSYQCS-CPKGYILQEDGRSCKDLDECATKQHNCQFLCVNTI----GGFTCKCPPGF 2515
Query: 455 AGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDACDED 510
C +D + + C + K C+ P S + R D G +C++
Sbjct: 2516 TQHHTSC---IDNNECTSDINLCGS----KGICQNTPGSFTCECQRGFSLDQTGSSCEDV 2568
Query: 511 ADGDGILNEQDNC 523
+ +G Q C
Sbjct: 2569 DECEGNHRCQHGC 2581
Score = 58.5 bits (140), Expect = 3e-08
Identities = 76/316 (24%), Positives = 113/316 (35%), Gaps = 88/316 (27%)
Query: 300 QCTDSRDGFQCGPCPEG--YTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDA----- 352
QC ++ F C CP+G Y + TC D+DEC+ PC GV C N F C+
Sbjct: 780 QCRNTPGSFVC-TCPKGFIYKPDLKTCEDIDECESSPCINGV-CKNSPGSFICECSSEST 837
Query: 353 ------------------------CPVGFTGPMVQG----------------------VG 366
C + G ++ G
Sbjct: 838 LDPTKTICIETIKGTCWQTVIDGRCEININGATLKSQCCSSLGAAWGSPCTLCQVDPICG 897
Query: 367 ISFAKSNKQVCTDIDECR--NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNC 424
+++ C DIDEC G C N +CVNT GS++C C G T D R C
Sbjct: 898 KGYSRIKGTQCEDIDECEVFPGVC-KNGLCVNTRGSFKC-QCPSGMTLD-----ATGRIC 950
Query: 425 RNPELNPCSV---NAQC---IEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPC- 477
+ L C + + +C I R C C VG A C ++ + + P+ E C
Sbjct: 951 LDIRLETCFLRYEDEECTLPIAGRHRMDACCCSVGAAWGTEEC-EECPMRNTPEYEELCP 1009
Query: 478 -----------SARNCKKD--NCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCV 524
+ + KD CK +P+ R+ IG G + +E+ NC
Sbjct: 1010 RGPGFATKEITNGKPFFKDINECKMIPSLCTHGKCRNTIGSFKCRCDSGFALDSEERNCT 1069
Query: 525 LIHNVDQRNSDKDIFG 540
++D+ D+ G
Sbjct: 1070 ---DIDECRISPDLCG 1082
Score = 58.5 bits (140), Expect = 3e-08
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 27/130 (20%)
Query: 313 CP--EGYTGNGITCI--DVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVG 366
CP EG+ N IT I D+DEC+ P C G CIN F+C CP G+
Sbjct: 1589 CPGGEGFRPNPITVILEDIDECQELPGLCQGG-KCINTFGSFQC-RCPTGY--------- 1637
Query: 367 ISFAKSNKQVCTDIDECRN-GACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCR 425
+ + +VC D++EC G C P + C NT+G+Y C C P Y Q+ G NC
Sbjct: 1638 --YLNEDTRVCDDVNECETPGICGPGT-CYNTVGNYTC-ICPPDYM--QVNG---GNNCM 1688
Query: 426 NPELNPCSVN 435
+ + C N
Sbjct: 1689 DMRRSLCYRN 1698
Score = 53.9 bits (128), Expect = 7e-07
Identities = 57/229 (24%), Positives = 88/229 (38%), Gaps = 47/229 (20%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDV-----------DECKYHPCYPGVH- 340
C G+ C ++R F+C CP G T G C+D+ +EC G H
Sbjct: 921 CKNGL-CVNTRGSFKC-QCPSGMTLDATGRICLDIRLETCFLRYEDEECTLP--IAGRHR 976
Query: 341 ----CINLSPGF---RCDACPVGFTG------PMVQGVGISFAKSNKQVCTDIDECRN-G 386
C ++ + C+ CP+ T P G + K DI+EC+
Sbjct: 977 MDACCCSVGAAWGTEECEECPMRNTPEYEELCPRGPGFATKEITNGKPFFKDINECKMIP 1036
Query: 387 ACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVN------AQCIE 440
+ + C NT+GS++C C G+ D ERNC +++ C ++ QC+
Sbjct: 1037 SLCTHGKCRNTIGSFKCR-CDSGFALDS-----EERNCT--DIDECRISPDLCGRGQCVN 1088
Query: 441 ERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKY 489
GD C C G+ + +DID + L C C Y
Sbjct: 1089 T-PGDFECKCDEGYESGFMMMKNCMDIDECQRDPLLCRGGVCHNTEGSY 1136
Score = 52.0 bits (123), Expect = 3e-06
Identities = 51/152 (33%), Positives = 59/152 (38%), Gaps = 28/152 (18%)
Query: 312 PCPEGYTGNGIT--CIDVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGI 367
PC G+ N T C DVDEC+ P C G +CIN F C CP G V
Sbjct: 230 PCRRGFIPNIRTGACQDVDECQAIPGLCQGG-NCINTVGSFECK-CPAGHKLNEVS---- 283
Query: 368 SFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRCGPCKPG-YTGDQIRGCKAERNC 424
Q C DIDEC G C C NT+ SY C C PG YT C +
Sbjct: 284 -------QKCEDIDECSTIPGIC-EGGECTNTVSSYFC-KCPPGFYTSPDGTRC---IDV 331
Query: 425 RNPELNPCSVNAQCIEERQGDVT---CVCGVG 453
R N +C + +T C C G
Sbjct: 332 RPGYCYTALTNGRCSNQLPQSITKMQCCCDAG 363
Score = 49.7 bits (117), Expect = 1e-05
Identities = 36/112 (32%), Positives = 51/112 (45%), Gaps = 12/112 (10%)
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCT----DIDECRN--GACVPNSICVNTLGSYRC 403
C+ CP+ T G + T DIDECR G C N +C+N +GS+RC
Sbjct: 1733 CEQCPIPSTDEFATLCGSQRPGFVIDIYTGLPVDIDECREIPGVC-ENGVCINMVGSFRC 1791
Query: 404 GPCKPG-YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
C G + D++ C+ C+N + C NA+CI G C C G+
Sbjct: 1792 -ECPVGFFYNDKLLVCEDIDECQNGPV--CQRNAECI-NTAGSYRCDCKPGY 1839
Score = 49.7 bits (117), Expect = 1e-05
Identities = 94/428 (21%), Positives = 138/428 (32%), Gaps = 137/428 (32%)
Query: 287 PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP--CYPGVHCINL 344
PR+C C + DG CP GY+ C D+DEC P C G C N
Sbjct: 1981 PRKCAPGTC-------QNLDGSYRCICPPGYSLQNEKCEDIDECVEEPEICALGT-CSNT 2032
Query: 345 SPGFRCDACPVGFT----GPMVQGVGISFAKSN--------------------------- 373
F+C CP GF+ G Q + +S+ +
Sbjct: 2033 EGSFKC-LCPEGFSLSSSGRRCQDLRMSYCYAKFEGGKCSSPKSRNHSKQECCCALKGEG 2091
Query: 374 ----------------KQVC--------------TDIDECRNGACVPNSICVNTLGSYRC 403
+Q+C D+DEC+ + C+NT GSYRC
Sbjct: 2092 WGDPCELCPTEPDEAFRQICPYGSGIIVGPDDSAVDMDECKEPDVCKHGQCINTDGSYRC 2151
Query: 404 GPCKPGY--TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
C GY G++ C C NPC N C + G C C G+ +
Sbjct: 2152 -ECPFGYILAGNE---CVDTDECSVG--NPCG-NGTC-KNVIGGFECTCEEGFEPGPMMT 2203
Query: 462 GKDVD-------------IDSYPDEELPC--------SARNCK-KDNCKYVPNSGQEDAD 499
+D++ +++Y E C R CK +D C+ G+ D
Sbjct: 2204 CEDINECAQNPLLCAFRCVNTYGSYECKCPVGYVLREDRRMCKDEDECE----EGKHDCT 2259
Query: 500 RDGI-------------GDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNC 546
+ G DG+G ++E + C + + + G C
Sbjct: 2260 EKQMECKNLIGTYMCICGPGYQRRPDGEGCVDENE-CQTKPGICENGRCLNTRGSYTCEC 2318
Query: 547 LSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF--PNRDQRDKD------GDGV 598
ND D C D+ +G +L N + NR+ K G G
Sbjct: 2319 -----ND--GFTASPNQDECLDNREGYCFTEVLQNMCQIGSSNRNPVTKSECCCDGGRGW 2371
Query: 599 GDACDSCP 606
G C+ CP
Sbjct: 2372 GPHCEICP 2379
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/133 (29%), Positives = 51/133 (38%), Gaps = 22/133 (16%)
Query: 326 DVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
D++ECK P C G C N F+C C GF S ++ CTDIDEC
Sbjct: 1028 DINECKMIPSLCTHG-KCRNTIGSFKC-RCDSGFA-----------LDSEERNCTDIDEC 1074
Query: 384 R-NGACVPNSICVNTLGSYRCGPCKPGYTGD--QIRGCKAERNCRNPELNPCSVNAQCIE 440
R + CVNT G + C C GY ++ C C+ +P
Sbjct: 1075 RISPDLCGRGQCVNTPGDFEC-KCDEGYESGFMMMKNCMDIDECQR---DPLLCRGGVCH 1130
Query: 441 ERQGDVTCVCGVG 453
+G C C G
Sbjct: 1131 NTEGSYRCECPPG 1143
Score = 42.7 bits (99), Expect = 0.002
Identities = 44/157 (28%), Positives = 59/157 (37%), Gaps = 32/157 (20%)
Query: 347 GFRCDACPVG----FTGPMVQGVGISFAKSNKQVCT-DIDECRNGACVPNSICVNTLGSY 401
G C CP + G G++ A S+ C D D C PN IC N G+Y
Sbjct: 693 GEPCQPCPAQNSAEYQALCSSGPGMTSAGSDINECALDPDIC------PNGICENLRGTY 746
Query: 402 RCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQ-----GDVTCVCGVGWAG 456
+C C GY D +NC ++N C +N+ + Q G C C
Sbjct: 747 KC-ICNSGYEVD-----STGKNC--VDINECVLNSLLCDNGQCRNTPGSFVCTC-----P 793
Query: 457 DGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNS 493
G+I D+ DE C + C CK P S
Sbjct: 794 KGFIYKPDLKTCEDIDE---CESSPCINGVCKNSPGS 827
Score = 38.5 bits (88), Expect = 0.030
Identities = 38/139 (27%), Positives = 56/139 (40%), Gaps = 29/139 (20%)
Query: 287 PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHC----- 341
P RC F G QC RD ++ GPC T I C+ G+ C
Sbjct: 163 PNRCACTYGFTGPQC--ERD-YRTGPC--------FTVISNQMCQGQ--LSGIVCTKTLC 209
Query: 342 ---INLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVN 396
+ + G C+ CP P +G C D+DEC+ G C + C+N
Sbjct: 210 CATVGRAWGHPCEMCPAQ-PHPCRRGF---IPNIRTGACQDVDECQAIPGLCQGGN-CIN 264
Query: 397 TLGSYRCGPCKPGYTGDQI 415
T+GS+ C C G+ +++
Sbjct: 265 TVGSFEC-KCPAGHKLNEV 282
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 99.0 bits (245), Expect = 2e-20
Identities = 65/177 (36%), Positives = 83/177 (46%), Gaps = 26/177 (14%)
Query: 291 DSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRC 350
+S+PC + +C ++ F CG C GY G C+DV+EC+ + C P HC N G++C
Sbjct: 5198 ESSPCHQ--RCFNAIGSFHCG-CEPGYQLKGRKCMDVNECRQNVCRPDQHCKNTRGGYKC 5254
Query: 351 -DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGSYRCGPCK 407
D CP G T K+ C DIDEC++G C N IC NT GSYRC C
Sbjct: 5255 IDLCPNGMT------------KAENGTCIDIDECKDGTHQCRYNQICENTRGSYRC-VCP 5301
Query: 408 PGYTGDQI-RGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVC--GVGWAGDGYIC 461
GY + R C C PC+ QC G C+C G GDG C
Sbjct: 5302 RGYRSQGVGRPCMDINECEQVP-KPCA--HQC-SNTPGSFKCICPPGQHLLGDGKSC 5354
Score = 68.9 bits (167), Expect = 2e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 19/132 (14%)
Query: 313 CPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKS 372
CPEG + TC+D+DEC+ C N ++C CP G+
Sbjct: 5419 CPEGSEASHDTCVDIDECENTDACQH-ECKNTFGSYQC-ICPPGYQ-----------LTH 5465
Query: 373 NKQVCTDIDEC--RNGACVPNSICVNTLGSYRC--GPCKPGYTGDQIRGCKAERNCRNPE 428
N + C DIDEC +N C PN +C N GSY+C PC P Y D + G +NC +
Sbjct: 5466 NGKTCQDIDECLEQNVHCGPNRMCFNMRGSYQCIDTPCPPNYQRDPVSGF-CLKNCPPND 5524
Query: 429 LNPCSVNAQCIE 440
L C+++ +E
Sbjct: 5525 LE-CALSPYALE 5535
Score = 67.8 bits (164), Expect = 5e-11
Identities = 48/125 (38%), Positives = 59/125 (47%), Gaps = 19/125 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQC-GPCPEGYT--GNGITCIDVDECK--YHPCYPGVHCINL 344
C N C C ++R G++C CP G T NG TCID+DECK H C C N
Sbjct: 5234 CRQNVCRPDQHCKNTRGGYKCIDLCPNGMTKAENG-TCIDIDECKDGTHQCRYNQICENT 5292
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCG 404
+RC CP G+ QGVG + C DI+EC C NT GS++C
Sbjct: 5293 RGSYRC-VCPRGYRS---QGVG--------RPCMDINECEQVPKPCAHQCSNTPGSFKC- 5339
Query: 405 PCKPG 409
C PG
Sbjct: 5340 ICPPG 5344
Score = 57.0 bits (136), Expect = 8e-08
Identities = 57/191 (29%), Positives = 81/191 (42%), Gaps = 39/191 (20%)
Query: 307 GFQCGPCPEGYTGNGIT--CIDVDECKY-HPCYPGVHCINLSPGFRCDACPVGFTGPMVQ 363
G + CP G+T + + C D DEC +PC H N + C +CP G T
Sbjct: 5086 GDRSNQCPSGFTLDSVGPFCADEDECAAGNPCSHSCH--NAMGTYYC-SCPKGLT----- 5137
Query: 364 GVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRC-GPCKPGY--TGDQIRGC 418
++ + C DIDEC G C C NT+GSYRC C G+ T D + C
Sbjct: 5138 ------IAADGRTCQDIDECALGRHTCHAGQDCDNTIGSYRCVVRCGSGFRRTSDGL-SC 5190
Query: 419 KAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCS 478
+ C+ E +PC + +C G C C G+ G C +D++ C
Sbjct: 5191 QDINECQ--ESSPC--HQRCF-NAIGSFHCGCEPGYQLKGRKC---MDVNE-------CR 5235
Query: 479 ARNCKKD-NCK 488
C+ D +CK
Sbjct: 5236 QNVCRPDQHCK 5246
>gi|110347437 latent transforming growth factor beta binding protein
4 isoform c [Homo sapiens]
Length = 1557
Score = 97.8 bits (242), Expect = 4e-20
Identities = 68/211 (32%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 280 PAPPTRPPRRCDSNP--CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKYHPC 335
P P + C +P C G +C ++ FQC CP G+ N G C DVDEC+ H
Sbjct: 679 PGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLA 736
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSI 393
PG C+N F+C CP G ++ CTD+DEC +GA C P+
Sbjct: 737 CPGQECVNSPGSFQCRTCPSGH-------------HLHRGRCTDVDECSSGAPPCGPHGH 783
Query: 394 CVNTLGSYRCGPCKPGYTGDQIR--GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCG 451
C NT GS+RC C PGY R C C + C + +C+ G C C
Sbjct: 784 CTNTEGSFRCS-CAPGYRAPSGRPGPCADVNECLEGDF--CFPHGECL-NTDGSFACTCA 839
Query: 452 VGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
G+ G +D+D +E+L C + C
Sbjct: 840 PGYR-PGPRGASCLDVDECSEEDL-CQSGIC 868
Score = 82.8 bits (203), Expect = 1e-15
Identities = 80/296 (27%), Positives = 101/296 (34%), Gaps = 63/296 (21%)
Query: 253 NTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGP 312
NT Q P+ FQ T + C+++ G +C +S FQC
Sbjct: 703 NTEGSFQCVCPMGFQPNTAGSECEDVD---------ECENHLACPGQECVNSPGSFQCRT 753
Query: 313 CPEGYTGNGITCIDVDECKYH--PCYPGVHCINLSPGFRCDACP-----VGFTGPMVQ-- 363
CP G+ + C DVDEC PC P HC N FRC P G GP
Sbjct: 754 CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 813
Query: 364 ---------------GVGISFAKS---------NKQVCTDIDECRNGACVPNSICVNTLG 399
SFA + C D+DEC + IC NT G
Sbjct: 814 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 873
Query: 400 SYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCV--CGVGW-A 455
S+ C C PG+ G + C CR E P +Q E G CV C G+ A
Sbjct: 874 SFEC-ICPPGHRAGPDLASCLDVDECR--ERGPALCGSQRCENSPGSYRCVRDCDPGYHA 930
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNCKKDNCKY------------VPNSGQEDAD 499
G C + Y E C A+ C+ Y P G +D D
Sbjct: 931 GPEGTCDDVDECQEYGPE--ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVD 984
Score = 70.1 bits (170), Expect = 9e-12
Identities = 67/225 (29%), Positives = 81/225 (36%), Gaps = 36/225 (16%)
Query: 269 PTPSTVVPPAPPAPPTRPPR-RCDSNPCFRGV-QCTDSRDGFQCGPCPEGY--TGNGITC 324
P PS P P + P C NP G +C G+ C C G+ + G C
Sbjct: 460 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCA-CDSGFRLSPQGTRC 518
Query: 325 IDVDECKY--HPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
IDVDEC+ PC PG C N FRC C GF A C D+DE
Sbjct: 519 IDVDECRRVPPPCAPG-RCENSPGSFRC-VCGPGFR-----------AGPRAAECLDVDE 565
Query: 383 CRNGACVPNSI----CVNTLGSYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQ 437
C VP C NT GS+ C C GY C+ C +P
Sbjct: 566 CHR---VPPPCDLGRCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQ---SPGLCGRG 618
Query: 438 CIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
+ G CVC G+ G + D+D E PC C
Sbjct: 619 ACKNLPGSFRCVCPAGFRGSAC----EEDVDECAQEPPPCGPGRC 659
Score = 68.9 bits (167), Expect = 2e-11
Identities = 70/233 (30%), Positives = 94/233 (40%), Gaps = 44/233 (18%)
Query: 294 PCFRGVQCTDSRDGFQCGPCPEGYTG--NGITCIDVDECKYHP--CYPGVHCINLSPGFR 349
PC G +C ++ F C CP GY +G +C DVDEC P C G C NL FR
Sbjct: 572 PCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFR 628
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRCGPCK 407
C CP GF G + D+DEC C P C NT GS+ C C
Sbjct: 629 C-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHCA-CP 671
Query: 408 PGYTGDQIRG----CKAERNC-RNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
G+ + RG C+ C R+P PC+ +C E +G CVC +G+ + G
Sbjct: 672 AGF---RSRGPGAPCQDVDECARSPP--PCTY-GRC-ENTEGSFQCVCPMGFQPN--TAG 722
Query: 463 KDVDIDSYPDEELPCSARNCKKD----NCKYVPNSGQEDADRDGIGDACDEDA 511
+ + + L C + C C+ P+ R D C A
Sbjct: 723 SECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGA 775
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/177 (31%), Positives = 75/177 (42%), Gaps = 37/177 (20%)
Query: 285 RPPRRCDSNPCFRGVQCTDSRDGFQC-GPCPEGY-TGNGITCIDVDECK-YHPCYPGVH- 340
R P C S +C +S ++C C GY G TC DVDEC+ Y P G
Sbjct: 901 RGPALCGSQ------RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 954
Query: 341 CINLSPGFRCD-ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTL 398
C N +RC AC G+ G C D+DECRN + C +++C N
Sbjct: 955 CENTPGSYRCTPACDPGYQPTPGGG------------CQDVDECRNRSFCGAHAVCQNLP 1002
Query: 399 GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSV-----NAQCIEERQGDVTCVC 450
GS++C C GY G + R+C ++N C A E +G CVC
Sbjct: 1003 GSFQC-LCDQGY-----EGARDGRHC--VDVNECETLQGVCGAALCENVEGSFLCVC 1051
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/184 (29%), Positives = 73/184 (39%), Gaps = 37/184 (20%)
Query: 300 QCTDSRDGFQCGPCPEGY-----TGNGITCIDVDECKY---HPCYPGVHCINLSPGFRCD 351
QC + CP G +G+ DVDEC+ C GV C+N +PG+ C
Sbjct: 1155 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC- 1212
Query: 352 ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPCKPG 409
C G+ + + + C D DEC + AC CVNT+GSY C C+P
Sbjct: 1213 YCSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPP 1259
Query: 410 YT--GDQIRGCKAERNCRNPELNPC--SVNAQCI-----EERQGDVT---CVCGVGWAGD 457
G Q R E + L C V A + +RQ T C+ G W D
Sbjct: 1260 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMD 1319
Query: 458 GYIC 461
+C
Sbjct: 1320 CALC 1323
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/140 (32%), Positives = 58/140 (41%), Gaps = 26/140 (18%)
Query: 277 PAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGF-QCGPCPEGYTGNGITCIDVDECKYHPC 335
PAPP P TR P R D+R F + PEG + G +E + C
Sbjct: 1422 PAPPGPGTRWPYRS-----------RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEEC 1470
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-----CVP 390
C N RC P GFT G + + C DI+EC CV
Sbjct: 1471 GILDGCTN----GRCVRVPEGFTCRCFDGYRLDMTR---MACVDINECDEAEAASPLCV- 1522
Query: 391 NSICVNTLGSYRCGPCKPGY 410
N+ C+NT GS+RC C+PG+
Sbjct: 1523 NARCLNTDGSFRC-ICRPGF 1541
Score = 37.7 bits (86), Expect = 0.052
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 311 GPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGF 357
GPCP G+ +C DVDEC C N G+ C CP GF
Sbjct: 275 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 320
Score = 37.7 bits (86), Expect = 0.052
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 377 CTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPC 432
C D+DEC G + C NT G Y C C G+ D R ++ + PC
Sbjct: 288 CEDVDECATGGRCQHGECANTRGGYTC-VCPDGFLLDSSRSSCISQHVISEAKGPC 342
>gi|110347412 latent transforming growth factor beta binding protein
4 isoform b [Homo sapiens]
Length = 1587
Score = 97.8 bits (242), Expect = 4e-20
Identities = 68/211 (32%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 280 PAPPTRPPRRCDSNP--CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKYHPC 335
P P + C +P C G +C ++ FQC CP G+ N G C DVDEC+ H
Sbjct: 709 PGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLA 766
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSI 393
PG C+N F+C CP G ++ CTD+DEC +GA C P+
Sbjct: 767 CPGQECVNSPGSFQCRTCPSGH-------------HLHRGRCTDVDECSSGAPPCGPHGH 813
Query: 394 CVNTLGSYRCGPCKPGYTGDQIR--GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCG 451
C NT GS+RC C PGY R C C + C + +C+ G C C
Sbjct: 814 CTNTEGSFRCS-CAPGYRAPSGRPGPCADVNECLEGDF--CFPHGECL-NTDGSFACTCA 869
Query: 452 VGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
G+ G +D+D +E+L C + C
Sbjct: 870 PGYR-PGPRGASCLDVDECSEEDL-CQSGIC 898
Score = 82.8 bits (203), Expect = 1e-15
Identities = 80/296 (27%), Positives = 101/296 (34%), Gaps = 63/296 (21%)
Query: 253 NTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGP 312
NT Q P+ FQ T + C+++ G +C +S FQC
Sbjct: 733 NTEGSFQCVCPMGFQPNTAGSECEDVD---------ECENHLACPGQECVNSPGSFQCRT 783
Query: 313 CPEGYTGNGITCIDVDECKYH--PCYPGVHCINLSPGFRCDACP-----VGFTGPMVQ-- 363
CP G+ + C DVDEC PC P HC N FRC P G GP
Sbjct: 784 CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 843
Query: 364 ---------------GVGISFAKS---------NKQVCTDIDECRNGACVPNSICVNTLG 399
SFA + C D+DEC + IC NT G
Sbjct: 844 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 903
Query: 400 SYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCV--CGVGW-A 455
S+ C C PG+ G + C CR E P +Q E G CV C G+ A
Sbjct: 904 SFEC-ICPPGHRAGPDLASCLDVDECR--ERGPALCGSQRCENSPGSYRCVRDCDPGYHA 960
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNCKKDNCKY------------VPNSGQEDAD 499
G C + Y E C A+ C+ Y P G +D D
Sbjct: 961 GPEGTCDDVDECQEYGPE--ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVD 1014
Score = 70.1 bits (170), Expect = 9e-12
Identities = 67/225 (29%), Positives = 81/225 (36%), Gaps = 36/225 (16%)
Query: 269 PTPSTVVPPAPPAPPTRPPR-RCDSNPCFRGV-QCTDSRDGFQCGPCPEGY--TGNGITC 324
P PS P P + P C NP G +C G+ C C G+ + G C
Sbjct: 490 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCA-CDSGFRLSPQGTRC 548
Query: 325 IDVDECKY--HPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
IDVDEC+ PC PG C N FRC C GF A C D+DE
Sbjct: 549 IDVDECRRVPPPCAPG-RCENSPGSFRC-VCGPGFR-----------AGPRAAECLDVDE 595
Query: 383 CRNGACVPNSI----CVNTLGSYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQ 437
C VP C NT GS+ C C GY C+ C +P
Sbjct: 596 CHR---VPPPCDLGRCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQ---SPGLCGRG 648
Query: 438 CIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
+ G CVC G+ G + D+D E PC C
Sbjct: 649 ACKNLPGSFRCVCPAGFRGSAC----EEDVDECAQEPPPCGPGRC 689
Score = 68.9 bits (167), Expect = 2e-11
Identities = 70/233 (30%), Positives = 94/233 (40%), Gaps = 44/233 (18%)
Query: 294 PCFRGVQCTDSRDGFQCGPCPEGYTG--NGITCIDVDECKYHP--CYPGVHCINLSPGFR 349
PC G +C ++ F C CP GY +G +C DVDEC P C G C NL FR
Sbjct: 602 PCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFR 658
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRCGPCK 407
C CP GF G + D+DEC C P C NT GS+ C C
Sbjct: 659 C-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHCA-CP 701
Query: 408 PGYTGDQIRG----CKAERNC-RNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
G+ + RG C+ C R+P PC+ +C E +G CVC +G+ + G
Sbjct: 702 AGF---RSRGPGAPCQDVDECARSPP--PCTY-GRC-ENTEGSFQCVCPMGFQPN--TAG 752
Query: 463 KDVDIDSYPDEELPCSARNCKKD----NCKYVPNSGQEDADRDGIGDACDEDA 511
+ + + L C + C C+ P+ R D C A
Sbjct: 753 SECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGA 805
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/177 (31%), Positives = 75/177 (42%), Gaps = 37/177 (20%)
Query: 285 RPPRRCDSNPCFRGVQCTDSRDGFQC-GPCPEGY-TGNGITCIDVDECK-YHPCYPGVH- 340
R P C S +C +S ++C C GY G TC DVDEC+ Y P G
Sbjct: 931 RGPALCGSQ------RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 984
Query: 341 CINLSPGFRCD-ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTL 398
C N +RC AC G+ G C D+DECRN + C +++C N
Sbjct: 985 CENTPGSYRCTPACDPGYQPTPGGG------------CQDVDECRNRSFCGAHAVCQNLP 1032
Query: 399 GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSV-----NAQCIEERQGDVTCVC 450
GS++C C GY G + R+C ++N C A E +G CVC
Sbjct: 1033 GSFQC-LCDQGY-----EGARDGRHC--VDVNECETLQGVCGAALCENVEGSFLCVC 1081
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/184 (29%), Positives = 73/184 (39%), Gaps = 37/184 (20%)
Query: 300 QCTDSRDGFQCGPCPEGY-----TGNGITCIDVDECKY---HPCYPGVHCINLSPGFRCD 351
QC + CP G +G+ DVDEC+ C GV C+N +PG+ C
Sbjct: 1185 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC- 1242
Query: 352 ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPCKPG 409
C G+ + + + C D DEC + AC CVNT+GSY C C+P
Sbjct: 1243 YCSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPP 1289
Query: 410 YT--GDQIRGCKAERNCRNPELNPC--SVNAQCI-----EERQGDVT---CVCGVGWAGD 457
G Q R E + L C V A + +RQ T C+ G W D
Sbjct: 1290 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMD 1349
Query: 458 GYIC 461
+C
Sbjct: 1350 CALC 1353
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/140 (32%), Positives = 58/140 (41%), Gaps = 26/140 (18%)
Query: 277 PAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGF-QCGPCPEGYTGNGITCIDVDECKYHPC 335
PAPP P TR P R D+R F + PEG + G +E + C
Sbjct: 1452 PAPPGPGTRWPYRS-----------RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEEC 1500
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-----CVP 390
C N RC P GFT G + + C DI+EC CV
Sbjct: 1501 GILDGCTN----GRCVRVPEGFTCRCFDGYRLDMTR---MACVDINECDEAEAASPLCV- 1552
Query: 391 NSICVNTLGSYRCGPCKPGY 410
N+ C+NT GS+RC C+PG+
Sbjct: 1553 NARCLNTDGSFRC-ICRPGF 1571
Score = 37.7 bits (86), Expect = 0.052
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 311 GPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGF 357
GPCP G+ +C DVDEC C N G+ C CP GF
Sbjct: 305 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 350
Score = 37.7 bits (86), Expect = 0.052
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 377 CTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPC 432
C D+DEC G + C NT G Y C C G+ D R ++ + PC
Sbjct: 318 CEDVDECATGGRCQHGECANTRGGYTC-VCPDGFLLDSSRSSCISQHVISEAKGPC 372
>gi|110347431 latent transforming growth factor beta binding protein
4 isoform a [Homo sapiens]
Length = 1624
Score = 97.8 bits (242), Expect = 4e-20
Identities = 68/211 (32%), Positives = 93/211 (44%), Gaps = 29/211 (13%)
Query: 280 PAPPTRPPRRCDSNP--CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKYHPC 335
P P + C +P C G +C ++ FQC CP G+ N G C DVDEC+ H
Sbjct: 746 PGAPCQDVDECARSPPPCTYG-RCENTEGSFQC-VCPMGFQPNTAGSECEDVDECENHLA 803
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSI 393
PG C+N F+C CP G ++ CTD+DEC +GA C P+
Sbjct: 804 CPGQECVNSPGSFQCRTCPSGH-------------HLHRGRCTDVDECSSGAPPCGPHGH 850
Query: 394 CVNTLGSYRCGPCKPGYTGDQIR--GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCG 451
C NT GS+RC C PGY R C C + C + +C+ G C C
Sbjct: 851 CTNTEGSFRCS-CAPGYRAPSGRPGPCADVNECLEGDF--CFPHGECL-NTDGSFACTCA 906
Query: 452 VGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
G+ G +D+D +E+L C + C
Sbjct: 907 PGYR-PGPRGASCLDVDECSEEDL-CQSGIC 935
Score = 82.8 bits (203), Expect = 1e-15
Identities = 80/296 (27%), Positives = 101/296 (34%), Gaps = 63/296 (21%)
Query: 253 NTIAECQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGP 312
NT Q P+ FQ T + C+++ G +C +S FQC
Sbjct: 770 NTEGSFQCVCPMGFQPNTAGSECEDVD---------ECENHLACPGQECVNSPGSFQCRT 820
Query: 313 CPEGYTGNGITCIDVDECKYH--PCYPGVHCINLSPGFRCDACP-----VGFTGPMVQ-- 363
CP G+ + C DVDEC PC P HC N FRC P G GP
Sbjct: 821 CPSGHHLHRGRCTDVDECSSGAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVN 880
Query: 364 ---------------GVGISFAKS---------NKQVCTDIDECRNGACVPNSICVNTLG 399
SFA + C D+DEC + IC NT G
Sbjct: 881 ECLEGDFCFPHGECLNTDGSFACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDG 940
Query: 400 SYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCV--CGVGW-A 455
S+ C C PG+ G + C CR E P +Q E G CV C G+ A
Sbjct: 941 SFEC-ICPPGHRAGPDLASCLDVDECR--ERGPALCGSQRCENSPGSYRCVRDCDPGYHA 997
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNCKKDNCKY------------VPNSGQEDAD 499
G C + Y E C A+ C+ Y P G +D D
Sbjct: 998 GPEGTCDDVDECQEYGPE--ICGAQRCENTPGSYRCTPACDPGYQPTPGGGCQDVD 1051
Score = 70.1 bits (170), Expect = 9e-12
Identities = 67/225 (29%), Positives = 81/225 (36%), Gaps = 36/225 (16%)
Query: 269 PTPSTVVPPAPPAPPTRPPR-RCDSNPCFRGV-QCTDSRDGFQCGPCPEGY--TGNGITC 324
P PS P P + P C NP G +C G+ C C G+ + G C
Sbjct: 527 PLPSIPAWTGPEIPESGPSSGMCQRNPQVCGPGRCISRPSGYTCA-CDSGFRLSPQGTRC 585
Query: 325 IDVDECKY--HPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
IDVDEC+ PC PG C N FRC C GF A C D+DE
Sbjct: 586 IDVDECRRVPPPCAPG-RCENSPGSFRC-VCGPGFR-----------AGPRAAECLDVDE 632
Query: 383 CRNGACVPNSI----CVNTLGSYRCGPCKPGY-TGDQIRGCKAERNCRNPELNPCSVNAQ 437
C VP C NT GS+ C C GY C+ C +P
Sbjct: 633 CHR---VPPPCDLGRCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQ---SPGLCGRG 685
Query: 438 CIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNC 482
+ G CVC G+ G + D+D E PC C
Sbjct: 686 ACKNLPGSFRCVCPAGFRGSAC----EEDVDECAQEPPPCGPGRC 726
Score = 68.9 bits (167), Expect = 2e-11
Identities = 70/233 (30%), Positives = 94/233 (40%), Gaps = 44/233 (18%)
Query: 294 PCFRGVQCTDSRDGFQCGPCPEGYTG--NGITCIDVDECKYHP--CYPGVHCINLSPGFR 349
PC G +C ++ F C CP GY +G +C DVDEC P C G C NL FR
Sbjct: 639 PCDLG-RCENTPGSFLC-VCPAGYQAAPHGASCQDVDECTQSPGLCGRGA-CKNLPGSFR 695
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRCGPCK 407
C CP GF G + D+DEC C P C NT GS+ C C
Sbjct: 696 C-VCPAGFRGSACE--------------EDVDECAQEPPPCGPGR-CDNTAGSFHCA-CP 738
Query: 408 PGYTGDQIRG----CKAERNC-RNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
G+ + RG C+ C R+P PC+ +C E +G CVC +G+ + G
Sbjct: 739 AGF---RSRGPGAPCQDVDECARSPP--PCTY-GRC-ENTEGSFQCVCPMGFQPN--TAG 789
Query: 463 KDVDIDSYPDEELPCSARNCKKD----NCKYVPNSGQEDADRDGIGDACDEDA 511
+ + + L C + C C+ P+ R D C A
Sbjct: 790 SECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSSGA 842
Score = 62.4 bits (150), Expect = 2e-09
Identities = 56/177 (31%), Positives = 75/177 (42%), Gaps = 37/177 (20%)
Query: 285 RPPRRCDSNPCFRGVQCTDSRDGFQC-GPCPEGY-TGNGITCIDVDECK-YHPCYPGVH- 340
R P C S +C +S ++C C GY G TC DVDEC+ Y P G
Sbjct: 968 RGPALCGSQ------RCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQR 1021
Query: 341 CINLSPGFRCD-ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTL 398
C N +RC AC G+ G C D+DECRN + C +++C N
Sbjct: 1022 CENTPGSYRCTPACDPGYQPTPGGG------------CQDVDECRNRSFCGAHAVCQNLP 1069
Query: 399 GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSV-----NAQCIEERQGDVTCVC 450
GS++C C GY G + R+C ++N C A E +G CVC
Sbjct: 1070 GSFQC-LCDQGY-----EGARDGRHC--VDVNECETLQGVCGAALCENVEGSFLCVC 1118
Score = 50.8 bits (120), Expect = 6e-06
Identities = 54/184 (29%), Positives = 73/184 (39%), Gaps = 37/184 (20%)
Query: 300 QCTDSRDGFQCGPCPEGY-----TGNGITCIDVDECKY---HPCYPGVHCINLSPGFRCD 351
QC + CP G +G+ DVDEC+ C GV C+N +PG+ C
Sbjct: 1222 QCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLFRDQVCKSGV-CVNTAPGYSC- 1279
Query: 352 ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPCKPG 409
C G+ + + + C D DEC + AC CVNT+GSY C C+P
Sbjct: 1280 YCSNGY-----------YYHTQRLECIDNDECADEEPAC-EGGRCVNTVGSYHC-TCEPP 1326
Query: 410 YT--GDQIRGCKAERNCRNPELNPC--SVNAQCI-----EERQGDVT---CVCGVGWAGD 457
G Q R E + L C V A + +RQ T C+ G W D
Sbjct: 1327 LVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYGEAWGMD 1386
Query: 458 GYIC 461
+C
Sbjct: 1387 CALC 1390
Score = 48.9 bits (115), Expect = 2e-05
Identities = 45/140 (32%), Positives = 58/140 (41%), Gaps = 26/140 (18%)
Query: 277 PAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGF-QCGPCPEGYTGNGITCIDVDECKYHPC 335
PAPP P TR P R D+R F + PEG + G +E + C
Sbjct: 1489 PAPPGPGTRWPYRS-----------RDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEEC 1537
Query: 336 YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-----CVP 390
C N RC P GFT G + + C DI+EC CV
Sbjct: 1538 GILDGCTN----GRCVRVPEGFTCRCFDGYRLDMTR---MACVDINECDEAEAASPLCV- 1589
Query: 391 NSICVNTLGSYRCGPCKPGY 410
N+ C+NT GS+RC C+PG+
Sbjct: 1590 NARCLNTDGSFRC-ICRPGF 1608
Score = 37.7 bits (86), Expect = 0.052
Identities = 19/47 (40%), Positives = 22/47 (46%), Gaps = 1/47 (2%)
Query: 311 GPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGF 357
GPCP G+ +C DVDEC C N G+ C CP GF
Sbjct: 342 GPCPTGFERVNGSCEDVDECATGGRCQHGECANTRGGYTC-VCPDGF 387
Score = 37.7 bits (86), Expect = 0.052
Identities = 18/56 (32%), Positives = 24/56 (42%), Gaps = 1/56 (1%)
Query: 377 CTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPC 432
C D+DEC G + C NT G Y C C G+ D R ++ + PC
Sbjct: 355 CEDVDECATGGRCQHGECANTRGGYTC-VCPDGFLLDSSRSSCISQHVISEAKGPC 409
>gi|34734064 fibulin 1 isoform B precursor [Homo sapiens]
Length = 601
Score = 96.7 bits (239), Expect = 9e-20
Identities = 80/240 (33%), Positives = 102/240 (42%), Gaps = 42/240 (17%)
Query: 289 RC-DSNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDEC--KYHPCYPGVHCIN 343
RC PC + QC D+ D C C GY +G++C DV+EC H C G CIN
Sbjct: 179 RCRGGGPCKQ--QCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 344 LSPGFRCD---ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTL 398
FRC +C G G + N C DIDEC +G C+P+ IC NTL
Sbjct: 236 TVGSFRCQRDSSC----------GTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTL 283
Query: 399 GSYRCGP---CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
GS+RC P CK G+ D + C C + PC + CI +G TC V
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-PCPIGHTCI-NTEGSYTCQKNVPNC 341
Query: 456 GDGYICGKD----VDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDAC 507
G GY ++ VD+D PC K C P S + + DGI C
Sbjct: 342 GRGYHLNEEGTRCVDVDECAPPAEPCG----KGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Score = 65.9 bits (159), Expect = 2e-10
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 41/190 (21%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGIT--CIDVDECKYHP---CYPGVHCINLSP 346
+ PC +G +C +S F+C C GY +GI+ C+DV+EC+ +P C G C N
Sbjct: 364 AEPCGKGHRCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC--GHKCENTLG 420
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
+ C +C VGF + + C DI+EC + C + C N GSY+C C
Sbjct: 421 SYLC-SCSVGFR-----------LSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YC 465
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSV-------NAQCIEERQGDVTCVC---GVGWAG 456
+ GY + G E +++ C++ + +CI G C C G A
Sbjct: 466 RRGYQLSDVDGVTCE------DIDECALPTGGHICSYRCI-NIPGSFQCSCPSSGYRLAP 518
Query: 457 DGYICGKDVD 466
+G C +D+D
Sbjct: 519 NGRNC-QDID 527
Score = 60.5 bits (145), Expect = 7e-09
Identities = 42/123 (34%), Positives = 56/123 (45%), Gaps = 25/123 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYT---GNGITCIDVDECKY----HPCYPGVHCI 342
C S+PC + +C + +QC C GY +G+TC D+DEC H C CI
Sbjct: 445 CSSSPCSQ--ECANVYGSYQCY-CRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCI 499
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGS 400
N+ F+C +CP G A + + C DIDEC G C N C N G
Sbjct: 500 NIPGSFQC-SCP---------SSGYRLAPNGRN-CQDIDECVTGIHNCSINETCFNIQGG 548
Query: 401 YRC 403
+RC
Sbjct: 549 FRC 551
Score = 57.4 bits (137), Expect = 6e-08
Identities = 51/178 (28%), Positives = 77/178 (43%), Gaps = 36/178 (20%)
Query: 288 RRC-DSNPCFR------GVQCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKYHPCYPG 338
R C D N C R G +C ++ + C C G+ + +G +C D++EC PC
Sbjct: 395 RMCVDVNECQRYPGRLCGHKCENTLGSYLCS-CSVGFRLSVDGRSCEDINECSSSPC--S 451
Query: 339 VHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVN 396
C N+ ++C C G+ V GV C DIDEC G + + C+N
Sbjct: 452 QECANVYGSYQC-YCRRGYQLSDVDGV----------TCEDIDECALPTGGHICSYRCIN 500
Query: 397 TLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE-----LNPCSVNAQCIEERQGDVTCV 449
GS++C GY R RNC++ + ++ CS+N C QG C+
Sbjct: 501 IPGSFQCSCPSSGY-----RLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRCL 552
>gi|34734068 fibulin 1 isoform A precursor [Homo sapiens]
Length = 566
Score = 96.7 bits (239), Expect = 9e-20
Identities = 80/240 (33%), Positives = 102/240 (42%), Gaps = 42/240 (17%)
Query: 289 RC-DSNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDEC--KYHPCYPGVHCIN 343
RC PC + QC D+ D C C GY +G++C DV+EC H C G CIN
Sbjct: 179 RCRGGGPCKQ--QCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 344 LSPGFRCD---ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTL 398
FRC +C G G + N C DIDEC +G C+P+ IC NTL
Sbjct: 236 TVGSFRCQRDSSC----------GTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTL 283
Query: 399 GSYRCGP---CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
GS+RC P CK G+ D + C C + PC + CI +G TC V
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-PCPIGHTCI-NTEGSYTCQKNVPNC 341
Query: 456 GDGYICGKD----VDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDAC 507
G GY ++ VD+D PC K C P S + + DGI C
Sbjct: 342 GRGYHLNEEGTRCVDVDECAPPAEPCG----KGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Score = 65.9 bits (159), Expect = 2e-10
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 41/190 (21%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGIT--CIDVDECKYHP---CYPGVHCINLSP 346
+ PC +G +C +S F+C C GY +GI+ C+DV+EC+ +P C G C N
Sbjct: 364 AEPCGKGHRCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC--GHKCENTLG 420
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
+ C +C VGF + + C DI+EC + C + C N GSY+C C
Sbjct: 421 SYLC-SCSVGFR-----------LSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YC 465
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSV-------NAQCIEERQGDVTCVC---GVGWAG 456
+ GY + G E +++ C++ + +CI G C C G A
Sbjct: 466 RRGYQLSDVDGVTCE------DIDECALPTGGHICSYRCI-NIPGSFQCSCPSSGYRLAP 518
Query: 457 DGYICGKDVD 466
+G C +D+D
Sbjct: 519 NGRNC-QDID 527
Score = 60.5 bits (145), Expect = 7e-09
Identities = 42/123 (34%), Positives = 56/123 (45%), Gaps = 25/123 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYT---GNGITCIDVDECKY----HPCYPGVHCI 342
C S+PC + +C + +QC C GY +G+TC D+DEC H C CI
Sbjct: 445 CSSSPCSQ--ECANVYGSYQCY-CRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCI 499
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGS 400
N+ F+C +CP G A + + C DIDEC G C N C N G
Sbjct: 500 NIPGSFQC-SCP---------SSGYRLAPNGRN-CQDIDECVTGIHNCSINETCFNIQGG 548
Query: 401 YRC 403
+RC
Sbjct: 549 FRC 551
Score = 57.4 bits (137), Expect = 6e-08
Identities = 51/178 (28%), Positives = 77/178 (43%), Gaps = 36/178 (20%)
Query: 288 RRC-DSNPCFR------GVQCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKYHPCYPG 338
R C D N C R G +C ++ + C C G+ + +G +C D++EC PC
Sbjct: 395 RMCVDVNECQRYPGRLCGHKCENTLGSYLCS-CSVGFRLSVDGRSCEDINECSSSPC--S 451
Query: 339 VHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVN 396
C N+ ++C C G+ V GV C DIDEC G + + C+N
Sbjct: 452 QECANVYGSYQC-YCRRGYQLSDVDGV----------TCEDIDECALPTGGHICSYRCIN 500
Query: 397 TLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE-----LNPCSVNAQCIEERQGDVTCV 449
GS++C GY R RNC++ + ++ CS+N C QG C+
Sbjct: 501 IPGSFQCSCPSSGY-----RLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRCL 552
>gi|34734066 fibulin 1 isoform D [Homo sapiens]
Length = 703
Score = 96.7 bits (239), Expect = 9e-20
Identities = 80/240 (33%), Positives = 102/240 (42%), Gaps = 42/240 (17%)
Query: 289 RC-DSNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDEC--KYHPCYPGVHCIN 343
RC PC + QC D+ D C C GY +G++C DV+EC H C G CIN
Sbjct: 179 RCRGGGPCKQ--QCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 344 LSPGFRCD---ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTL 398
FRC +C G G + N C DIDEC +G C+P+ IC NTL
Sbjct: 236 TVGSFRCQRDSSC----------GTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTL 283
Query: 399 GSYRCGP---CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
GS+RC P CK G+ D + C C + PC + CI +G TC V
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-PCPIGHTCI-NTEGSYTCQKNVPNC 341
Query: 456 GDGYICGKD----VDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDAC 507
G GY ++ VD+D PC K C P S + + DGI C
Sbjct: 342 GRGYHLNEEGTRCVDVDECAPPAEPCG----KGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Score = 65.9 bits (159), Expect = 2e-10
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 41/190 (21%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGIT--CIDVDECKYHP---CYPGVHCINLSP 346
+ PC +G +C +S F+C C GY +GI+ C+DV+EC+ +P C G C N
Sbjct: 364 AEPCGKGHRCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC--GHKCENTLG 420
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
+ C +C VGF + + C DI+EC + C + C N GSY+C C
Sbjct: 421 SYLC-SCSVGFR-----------LSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YC 465
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSV-------NAQCIEERQGDVTCVC---GVGWAG 456
+ GY + G E +++ C++ + +CI G C C G A
Sbjct: 466 RRGYQLSDVDGVTCE------DIDECALPTGGHICSYRCI-NIPGSFQCSCPSSGYRLAP 518
Query: 457 DGYICGKDVD 466
+G C +D+D
Sbjct: 519 NGRNC-QDID 527
Score = 60.5 bits (145), Expect = 7e-09
Identities = 42/123 (34%), Positives = 56/123 (45%), Gaps = 25/123 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYT---GNGITCIDVDECKY----HPCYPGVHCI 342
C S+PC + +C + +QC C GY +G+TC D+DEC H C CI
Sbjct: 445 CSSSPCSQ--ECANVYGSYQCY-CRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCI 499
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGS 400
N+ F+C +CP G A + + C DIDEC G C N C N G
Sbjct: 500 NIPGSFQC-SCP---------SSGYRLAPNGRN-CQDIDECVTGIHNCSINETCFNIQGG 548
Query: 401 YRC 403
+RC
Sbjct: 549 FRC 551
Score = 57.4 bits (137), Expect = 6e-08
Identities = 51/178 (28%), Positives = 77/178 (43%), Gaps = 36/178 (20%)
Query: 288 RRC-DSNPCFR------GVQCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKYHPCYPG 338
R C D N C R G +C ++ + C C G+ + +G +C D++EC PC
Sbjct: 395 RMCVDVNECQRYPGRLCGHKCENTLGSYLCS-CSVGFRLSVDGRSCEDINECSSSPC--S 451
Query: 339 VHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVN 396
C N+ ++C C G+ V GV C DIDEC G + + C+N
Sbjct: 452 QECANVYGSYQC-YCRRGYQLSDVDGV----------TCEDIDECALPTGGHICSYRCIN 500
Query: 397 TLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE-----LNPCSVNAQCIEERQGDVTCV 449
GS++C GY R RNC++ + ++ CS+N C QG C+
Sbjct: 501 IPGSFQCSCPSSGY-----RLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRCL 552
>gi|34734062 fibulin 1 isoform C precursor [Homo sapiens]
Length = 683
Score = 96.7 bits (239), Expect = 9e-20
Identities = 80/240 (33%), Positives = 102/240 (42%), Gaps = 42/240 (17%)
Query: 289 RC-DSNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDEC--KYHPCYPGVHCIN 343
RC PC + QC D+ D C C GY +G++C DV+EC H C G CIN
Sbjct: 179 RCRGGGPCKQ--QCRDTGDEVVCS-CFVGYQLLSDGVSCEDVNECITGSHSCRLGESCIN 235
Query: 344 LSPGFRCD---ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTL 398
FRC +C G G + N C DIDEC +G C+P+ IC NTL
Sbjct: 236 TVGSFRCQRDSSC----------GTGYELTEDNS--CKDIDECESGIHNCLPDFICQNTL 283
Query: 399 GSYRCGP---CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
GS+RC P CK G+ D + C C + PC + CI +G TC V
Sbjct: 284 GSFRCRPKLQCKSGFIQDALGNCIDINECLSISA-PCPIGHTCI-NTEGSYTCQKNVPNC 341
Query: 456 GDGYICGKD----VDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDAC 507
G GY ++ VD+D PC K C P S + + DGI C
Sbjct: 342 GRGYHLNEEGTRCVDVDECAPPAEPCG----KGHRCVNSPGSFRCECKTGYYFDGISRMC 397
Score = 65.9 bits (159), Expect = 2e-10
Identities = 56/190 (29%), Positives = 87/190 (45%), Gaps = 41/190 (21%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGIT--CIDVDECKYHP---CYPGVHCINLSP 346
+ PC +G +C +S F+C C GY +GI+ C+DV+EC+ +P C G C N
Sbjct: 364 AEPCGKGHRCVNSPGSFRC-ECKTGYYFDGISRMCVDVNECQRYPGRLC--GHKCENTLG 420
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
+ C +C VGF + + C DI+EC + C + C N GSY+C C
Sbjct: 421 SYLC-SCSVGFR-----------LSVDGRSCEDINECSSSPC--SQECANVYGSYQC-YC 465
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSV-------NAQCIEERQGDVTCVC---GVGWAG 456
+ GY + G E +++ C++ + +CI G C C G A
Sbjct: 466 RRGYQLSDVDGVTCE------DIDECALPTGGHICSYRCI-NIPGSFQCSCPSSGYRLAP 518
Query: 457 DGYICGKDVD 466
+G C +D+D
Sbjct: 519 NGRNC-QDID 527
Score = 63.2 bits (152), Expect = 1e-09
Identities = 50/160 (31%), Positives = 65/160 (40%), Gaps = 36/160 (22%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYT---GNGITCIDVDECKY----HPCYPGVHCI 342
C S+PC + +C + +QC C GY +G+TC D+DEC H C CI
Sbjct: 445 CSSSPCSQ--ECANVYGSYQCY-CRRGYQLSDVDGVTCEDIDECALPTGGHIC--SYRCI 499
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGS 400
N+ F+C +CP G A + + C DIDEC G C N C N G
Sbjct: 500 NIPGSFQC-SCP---------SSGYRLAPNGRN-CQDIDECVTGIHNCSINETCFNIQGG 548
Query: 401 YRC--GPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQC 438
+RC C Y C E PC N +C
Sbjct: 549 FRCLAFECPENYRRSAATRC---------ERLPCHENREC 579
Score = 57.4 bits (137), Expect = 6e-08
Identities = 51/178 (28%), Positives = 77/178 (43%), Gaps = 36/178 (20%)
Query: 288 RRC-DSNPCFR------GVQCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKYHPCYPG 338
R C D N C R G +C ++ + C C G+ + +G +C D++EC PC
Sbjct: 395 RMCVDVNECQRYPGRLCGHKCENTLGSYLCS-CSVGFRLSVDGRSCEDINECSSSPC--S 451
Query: 339 VHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVN 396
C N+ ++C C G+ V GV C DIDEC G + + C+N
Sbjct: 452 QECANVYGSYQC-YCRRGYQLSDVDGV----------TCEDIDECALPTGGHICSYRCIN 500
Query: 397 TLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE-----LNPCSVNAQCIEERQGDVTCV 449
GS++C GY R RNC++ + ++ CS+N C QG C+
Sbjct: 501 IPGSFQCSCPSSGY-----RLAPNGRNCQDIDECVTGIHNCSINETCF-NIQGGFRCL 552
>gi|112420992 crumbs homolog 2 [Homo sapiens]
Length = 1285
Score = 94.0 bits (232), Expect = 6e-19
Identities = 70/245 (28%), Positives = 100/245 (40%), Gaps = 56/245 (22%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S PC G C D F+C C GY G +D+DEC+ PC G C +L GFR
Sbjct: 150 CASAPCLHGGSCLDGVGSFRC-VCAPGYGGTRCQ-LDLDECQSQPCAHGGTCHDLVNGFR 207
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
CD G+ G + ++ EC + C N+ C+ LGS+RC C PG
Sbjct: 208 CDCAGTGYEGTHCE--------------REVLECASAPCEHNASCLEGLGSFRC-LCWPG 252
Query: 410 YTGDQIRGCKA-ERNCRNPELNPCSVNAQCIE--------------------ERQGDVTC 448
Y+G+ C+ E C + +PC +C++ C
Sbjct: 253 YSGEL---CEVDEDECAS---SPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLC 306
Query: 449 VCGVGWAGDGYICGKDVDIDSYPDEELPCSARNC-KKDNCKYVPNSGQEDADRDGIGDAC 507
C G+ +G CG +VD C++R C +C+ +PN Q G C
Sbjct: 307 HCPPGF--EGADCGVEVD---------ECASRPCLNGGHCQDLPNGFQCHCPDGYAGPTC 355
Query: 508 DEDAD 512
+ED D
Sbjct: 356 EEDVD 360
Score = 89.0 bits (219), Expect = 2e-17
Identities = 63/248 (25%), Positives = 93/248 (37%), Gaps = 83/248 (33%)
Query: 283 PTRPPRRCDSNPCFRGVQCTDSRDG-FQCGPC-----------------PEGYTGNGITC 324
P+ PP C S+PC G +C + G + CGP P+G G C
Sbjct: 35 PSEPPSACASDPCAPGTECQATESGGYTCGPMEPRGCATQPCHHGALCVPQGPDPTGFRC 94
Query: 325 ------------IDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKS 372
+D+DEC PC+ G C NL+ + C CP+G+ G +
Sbjct: 95 YCVPGFQGPRCELDIDECASRPCHHGATCRNLADRYECH-CPLGYAGVTCE--------- 144
Query: 373 NKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIR---------------- 416
++DEC + C+ C++ +GS+RC C PGY G + +
Sbjct: 145 -----MEVDECASAPCLHGGSCLDGVGSFRC-VCAPGYGGTRCQLDLDECQSQPCAHGGT 198
Query: 417 ------------------GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDG 458
G ER PC NA C+ E G C+C G++G+
Sbjct: 199 CHDLVNGFRCDCAGTGYEGTHCEREVLECASAPCEHNASCL-EGLGSFRCLCWPGYSGE- 256
Query: 459 YICGKDVD 466
+C D D
Sbjct: 257 -LCEVDED 263
Score = 71.2 bits (173), Expect = 4e-12
Identities = 57/202 (28%), Positives = 80/202 (39%), Gaps = 55/202 (27%)
Query: 290 CDSNPCFRGVQCTDSRD---------------------GFQCGPCPEGYTGNGITC-IDV 327
C S+PC G +C D GF C CP G+ G C ++V
Sbjct: 265 CASSPCQHGGRCLQRSDPALYGGVQAAFPGAFSFRHAAGFLCH-CPPGF--EGADCGVEV 321
Query: 328 DECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA 387
DEC PC G HC +L GF+C CP G+ GP + D+DEC +
Sbjct: 322 DECASRPCLNGGHCQDLPNGFQCH-CPDGYAGPTCE--------------EDVDECLSDP 366
Query: 388 CVPNSICVNTLGSYRCGPCKPGYTGD----QIRGCKAERNCRNPELNPCSVNAQCIEERQ 443
C+ C +T+ Y C C + G Q+ GC+ + C + A CI +
Sbjct: 367 CLHGGTCSDTVAGYIC-RCPETWGGRDCSVQLTGCQG---------HTCPLAATCIPIFE 416
Query: 444 GDV-TCVCGVGWAGDGYICGKD 464
V + VC G CG++
Sbjct: 417 SGVHSYVCHCPPGTHGPFCGQN 438
Score = 55.8 bits (133), Expect = 2e-07
Identities = 52/186 (27%), Positives = 62/186 (33%), Gaps = 31/186 (16%)
Query: 277 PAPPAP--PTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP 334
P PAP R C +PC C D D F C C G+ G VD C P
Sbjct: 1045 PGTPAPILGCRGAPVCAPSPCLHDGACRDLFDAFACA-CGPGWEGPRCEA-HVDPCHSAP 1102
Query: 335 CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSIC 394
C G + F C CP GF GP + S S C D C G+ N C
Sbjct: 1103 CARGRCHTHPDGRFEC-RCPPGFGGPRCRLPVPSKECSLNVTCLDGSPCEGGSPAANCSC 1161
Query: 395 VNTLGSYRCG----PCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVC 450
+ L RC PC E NPC +N G C+C
Sbjct: 1162 LEGLAGQRCQVPTLPC---------------------EANPC-LNGGTCRAAGGVSECIC 1199
Query: 451 GVGWAG 456
++G
Sbjct: 1200 NARFSG 1205
Score = 44.7 bits (104), Expect = 4e-04
Identities = 25/71 (35%), Positives = 30/71 (42%), Gaps = 3/71 (4%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C +PCF G C + + F C CP +TG TC C PC P C + GF
Sbjct: 811 CSPDPCFNGGTCLVTWNDFHC-TCPANFTGP--TCAQQLWCPGQPCLPPATCEEVPDGFV 867
Query: 350 CDACPVGFTGP 360
C A GP
Sbjct: 868 CVAEATFREGP 878
Score = 37.4 bits (85), Expect = 0.068
Identities = 21/80 (26%), Positives = 27/80 (33%), Gaps = 16/80 (20%)
Query: 324 CIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
C+ D C PC+ G C+ F C CP FTGP C C
Sbjct: 805 CVSEDMCSPDPCFNGGTCLVTWNDFHC-TCPANFTGP---------------TCAQQLWC 848
Query: 384 RNGACVPNSICVNTLGSYRC 403
C+P + C + C
Sbjct: 849 PGQPCLPPATCEEVPDGFVC 868
>gi|134244285 Notch homolog 3 [Homo sapiens]
Length = 2321
Score = 92.4 bits (228), Expect = 2e-18
Identities = 62/211 (29%), Positives = 88/211 (41%), Gaps = 35/211 (16%)
Query: 282 PPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKY-HPCYPGVH 340
P P C S+PC G +C+ DG CP GY G DVDEC+ PC G
Sbjct: 115 PDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRS-DVDECRVGEPCRHGGT 173
Query: 341 CINLSPGFRCDACPVGFTGPMVQGVGISFAKS---NKQVC-------------------- 377
C+N FRC CP G+TGP+ + + A S N C
Sbjct: 174 CLNTPGSFRCQ-CPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQN 232
Query: 378 --TDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVN 435
++D+C C+ CV+ + +Y C C P +TG + C + + + N C
Sbjct: 233 CEVNVDDCPGHRCLNGGTCVDGVNTYNC-QCPPEWTG---QFCTEDVDECQLQPNACHNG 288
Query: 436 AQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
C G +CVC GW G+ C +++D
Sbjct: 289 GTCFNTLGGH-SCVCVNGWTGES--CSQNID 316
Score = 87.8 bits (216), Expect = 4e-17
Identities = 107/424 (25%), Positives = 159/424 (37%), Gaps = 84/424 (19%)
Query: 290 CDSNPCFRGVQC-TDSRDGFQCGPCPEGYTGNGITCIDVDECKY--HPCYPGVHCINLSP 346
C SNPC C T+ +G CP G+TG G DVDEC +PC C+N
Sbjct: 355 CVSNPCHEDAICDTNPVNGRAICTCPPGFTG-GACDQDVDECSIGANPCEHLGRCVNTQG 413
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
F C C G+TGP + TD++EC +G C + C++ +G + C C
Sbjct: 414 SFLCQ-CGRGYTGPRCE--------------TDVNECLSGPCRNQATCLDRIGQFTC-IC 457
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
G+TG E + + +PC VN ++R +C C G++G C DVD
Sbjct: 458 MAGFTGTY-----CEVDIDECQSSPC-VNGGVCKDRVNGFSCTCPSGFSGS--TCQLDVD 509
Query: 467 IDSYPDEELPCSARNCKKDNCKYVPNSGQEDADR-DGIGDACDEDADGDGILNEQDNCVL 525
C++ C+ +G + D+ DG C E +G D+C
Sbjct: 510 ---------ECASTPCR---------NGAKCVDQPDGYECRCAEGFEGTLCDRNVDDC-- 549
Query: 526 IHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKF 585
+ D + + + G A +C AC G ++ +D C
Sbjct: 550 --SPDPCHHGRCVDGIASFSC------------------ACAPGYTGTRCESQVDECRSQ 589
Query: 586 PNRDQRDKDGDGVGDACDSCPDVSNPNQSDVD-NDLVGDSCDTNQDSDGDGHQDSTDN-- 642
P R K D V CP + +V+ +D + C DG D
Sbjct: 590 PCR-HGGKCLDLVDKYLCRCPSGTTGVNCEVNIDDCASNPCTFGVCRDGINRYDCVCQPG 648
Query: 643 -----CPTVINSAQLDTDKDGIGDECDDDDDNDGIPDLVPPG--PDNCRLVPNPAQEDSN 695
C IN + + G G C D + +G L PPG P C +P +
Sbjct: 649 FTGPLCNVEIN--ECASSPCGEGGSCVDGE--NGFRCLCPPGSLPPLCLPPSHPCAHEPC 704
Query: 696 SDGV 699
S G+
Sbjct: 705 SHGI 708
Score = 86.7 bits (213), Expect = 1e-16
Identities = 60/178 (33%), Positives = 77/178 (43%), Gaps = 27/178 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C+S PC G C+ GF C CP G G C + C +PC G C +
Sbjct: 738 CESQPCRAGGTCSSDGMGFHC-TCPPGVQGR--QCELLSPCTPNPCEHGGRCESAPGQLP 794
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTLGSYRCGPCKP 408
+CP G+ GP Q D+DEC A C P+ IC N GS+ C C
Sbjct: 795 VCSCPQGWQGPRCQ--------------QDVDECAGPAPCGPHGICTNLAGSFSC-TCHG 839
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
GYTG C + N +P NPC C ++ G +C C G+AG C +DVD
Sbjct: 840 GYTGP---SCDQDINDCDP--NPCLNGGSC-QDGVGSFSCSCLPGFAGPR--CARDVD 889
Score = 80.9 bits (198), Expect = 5e-15
Identities = 54/169 (31%), Positives = 79/169 (46%), Gaps = 18/169 (10%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C + PC G C G+ C C GY G+ DVDEC PC G CI+L +
Sbjct: 1088 CLAQPCQHGGTCRGYMGGYMC-ECLPGYNGDNCED-DVDECASQPCQHGGSCIDLVARYL 1145
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG-ACVPNSICVNTLGSYRCGPCKP 408
C +CP G G + + N+ C +G C+ N CV+ +G +RC C P
Sbjct: 1146 C-SCPPGTLGVL--------CEINEDDCGPGPPLDSGPRCLHNGTCVDLVGGFRC-TCPP 1195
Query: 409 GYTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
GYTG + C+A+ N CR+ + C+++ G C+C G++G
Sbjct: 1196 GYTGLR---CEADINECRSGACHAAHTR-DCLQDPGGGFRCLCHAGFSG 1240
Score = 79.3 bits (194), Expect = 2e-14
Identities = 79/315 (25%), Positives = 107/315 (33%), Gaps = 76/315 (24%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
CD NPC G C D F C C G+ G DVDEC +PC PG C + F
Sbjct: 853 CDPNPCLNGGSCQDGVGSFSCS-CLPGFAGPR-CARDVDECLSNPCGPGT-CTDHVASFT 909
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C CP G+ G + D+ +C +C CV+ + S+ C C+PG
Sbjct: 910 C-TCPPGYGGFHCE--------------QDLPDCSPSSCFNGGTCVDGVNSFSC-LCRPG 953
Query: 410 YTGDQIR------------------------GCKAERNCRNPEL---------NPCSVNA 436
YTG + C + P+ PC
Sbjct: 954 YTGAHCQHEADPCLSRPCLHGGVCSAAHPGFRCTCLESFTGPQCQTLVDWCSRQPCQNGG 1013
Query: 437 QCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQE 496
+C+ Q C+C GW+ G +C DI S P E + C+ E
Sbjct: 1014 RCV---QTGAYCLCPPGWS--GRLC----DIRSLPCREAAAQIGVRLEQLCQAGGQCVDE 1064
Query: 497 DADRDGIGDACDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKD 556
D+ + C E G E D C L + + G CL N
Sbjct: 1065 DSSHYCV---CPEGRTGSHCEQEVDPC-LAQPCQHGGTCRGYMGGYMCECLPGYN----- 1115
Query: 557 TDGDGRGDACDDDMD 571
GD C+DD+D
Sbjct: 1116 ------GDNCEDDVD 1124
Score = 73.6 bits (179), Expect = 9e-13
Identities = 77/285 (27%), Positives = 98/285 (34%), Gaps = 74/285 (25%)
Query: 277 PAPPAPPTRP--------------PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGI 322
P PP PP R P D +PC G +CT CP G+ G
Sbjct: 17 PPPPPPPVRALPLLLLLAGPGAAAPPCLDGSPCANGGRCTQLPSREAACLCPPGWVGE-- 74
Query: 323 TCIDVDECKYHPCYPGVHC----INLSPGFRCDACPVGFTG------------PMVQGVG 366
C D C PC C + + F C CP GF G P G
Sbjct: 75 RCQLEDPCHSGPCAGRGVCQSSVVAGTARFSC-RCPRGFRGPDCSLPDPCLSSPCAHGAR 133
Query: 367 ISFAKSNKQVC------------TDIDECRNG-ACVPNSICVNTLGSYRCGPCKPGYTGD 413
S + +C +D+DECR G C C+NT GS+RC C GYTG
Sbjct: 134 CSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNTPGSFRC-QCPAGYTGP 192
Query: 414 QIRGCKAERNCRNPEL----NPCSVNAQCIEERQGDVT--CVCGVGWAGDGYICGKDVDI 467
C NP + +PC C + GD+T C C G+ G +V++
Sbjct: 193 L---------CENPAVPCAPSPCRNGGTC--RQSGDLTYDCACLPGFEGQNC----EVNV 237
Query: 468 DSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDAD 512
D P R C N+ + G C ED D
Sbjct: 238 DDCPGH------RCLNGGTCVDGVNTYNCQCPPEWTGQFCTEDVD 276
Score = 71.2 bits (173), Expect = 4e-12
Identities = 56/194 (28%), Positives = 77/194 (39%), Gaps = 36/194 (18%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECK-YHPCYPGVHCINLSPGF 348
C NPC G +C + CP+G+ G DVDEC PC P C NL+ F
Sbjct: 775 CTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQ-QDVDECAGPAPCGPHGICTNLAGSF 833
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C C G+TGP DI++C C+ C + +GS+ C C P
Sbjct: 834 SC-TCHGGYTGPSCD--------------QDINDCDPNPCLNGGSCQDGVGSFSCS-CLP 877
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDID 468
G+ G + R+ NPC + TC C G+ G+ C +D+
Sbjct: 878 GFAGP-----RCARDVDECLSNPCGPGT--CTDHVASFTCTCPPGYG--GFHCEQDL--- 925
Query: 469 SYPDEELPCSARNC 482
PD CS +C
Sbjct: 926 --PD----CSPSSC 933
Score = 52.0 bits (123), Expect = 3e-06
Identities = 61/222 (27%), Positives = 80/222 (36%), Gaps = 36/222 (16%)
Query: 266 FQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRD-----GFQCGPCPEGYTGN 320
F P TV+ P C+S PC G QC S F C C + + G
Sbjct: 1238 FSGPRCQTVLSP------------CESQPCQHGGQCRPSPGPGGGLTFTC-HCAQPFWGP 1284
Query: 321 GITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDI 380
+ C+ C GV C G RC ACP G +GP + S ++ C
Sbjct: 1285 RCERV-ARSCRELQCPVGVPCQQTPRGPRC-ACPPGLSGPSCRSFPGSPPGASNASCAAA 1342
Query: 381 DECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIE 440
G+C P + +RC C G+TG + C+A P A C +
Sbjct: 1343 PCLHGGSCRPAPLA----PFFRCA-CAQGWTGPR---CEAPAAAPEVSEEPRCPRAAC-Q 1393
Query: 441 ERQGDVTC--VC---GVGWAGDGYICGKDVDIDSYPDEELPC 477
++GD C C G GW DG C V E L C
Sbjct: 1394 AKRGDQRCDRECNSPGCGW--DGGDCSLSVGDPWRQCEALQC 1433
Score = 42.4 bits (98), Expect = 0.002
Identities = 71/336 (21%), Positives = 103/336 (30%), Gaps = 83/336 (24%)
Query: 334 PCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSI 393
PC G C L CP G+ G + C D C +G C +
Sbjct: 48 PCANGGRCTQLPSREAACLCPPGWVG---------------ERCQLEDPCHSGPCAGRGV 92
Query: 394 CVNTL----GSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCV 449
C +++ + C C G+ G C C + +PC+ A+C G C
Sbjct: 93 CQSSVVAGTARFSC-RCPRGFRGPD---CSLPDPCLS---SPCAHGARCSVGPDGRFLCS 145
Query: 450 CGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDE 509
C G+ G C DVD + PC C P S + G C+
Sbjct: 146 CPPGYQGRS--CRSDVDECRVGE---PCR----HGGTCLNTPGSFRCQCPAGYTGPLCEN 196
Query: 510 DA---------DGDGILNEQD---NCVLIHNVDQRNSD---KDIFGDACDN---CLSVLN 551
A +G D +C + + +N + D G C N C+ +N
Sbjct: 197 PAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGVN 256
Query: 552 NDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPDVSNP 611
+ G C +D +D C PN AC
Sbjct: 257 TYNCQCPPEWTGQFCTED---------VDECQLQPN-------------ACH-------- 286
Query: 612 NQSDVDNDLVGDSCDTNQDSDGDGHQDSTDNCPTVI 647
N N L G SC G+ + D+C T +
Sbjct: 287 NGGTCFNTLGGHSCVCVNGWTGESCSQNIDDCATAV 322
Score = 41.2 bits (95), Expect = 0.005
Identities = 48/197 (24%), Positives = 61/197 (30%), Gaps = 46/197 (23%)
Query: 289 RCDSNPCFRGVQCTDSRDGFQCGPCPEGYT-------GNGITCI------------DVDE 329
RC P + G++C + + G C +T G G C+ +
Sbjct: 1190 RCTCPPGYTGLRCEADINECRSGACHAAHTRDCLQDPGGGFRCLCHAGFSGPRCQTVLSP 1249
Query: 330 CKYHPCYPGVHCINLSPG------FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
C+ PC G C SPG F C C F GP + V S C
Sbjct: 1250 CESQPCQHGGQC-RPSPGPGGGLTFTCH-CAQPFWGPRCERVARS--------------C 1293
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIR---GCKAERNCRNPELNPCSVNAQCIE 440
R C C T RC C PG +G R G + + PC C
Sbjct: 1294 RELQCPVGVPCQQTPRGPRCA-CPPGLSGPSCRSFPGSPPGASNASCAAAPCLHGGSCRP 1352
Query: 441 ERQGD-VTCVCGVGWAG 456
C C GW G
Sbjct: 1353 APLAPFFRCACAQGWTG 1369
>gi|194328809 latent transforming growth factor beta binding protein
3 isoform 1 [Homo sapiens]
Length = 1303
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 37/216 (17%)
Query: 290 CDSNPCF--RGVQCTDSRDGFQCGPCPEGYT----GNGITCIDVDEC-KYHPCYPGVHCI 342
C++ PC RG+ C ++ + C C GY G +C+D++EC K H C G CI
Sbjct: 620 CEAEPCGPGRGI-CMNTGGSYNCH-CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI 677
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYR 402
N ++C+ P G S VC DIDECR+ + P+ C N GS++
Sbjct: 678 NFPGHYKCNCYP-----------GYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK 726
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYI 460
C C+PGY C+ C E +PCS E G C C G+ A DG
Sbjct: 727 CIACQPGYRSQGGGACRDVNEC--AEGSPCSPG--WCENLPGSFRCTCAQGYAPAPDGRS 782
Query: 461 CGKDVDIDSYPDEELPCSARN-CKKDNCKYVPNSGQ 495
C +D+D C A + C C P S Q
Sbjct: 783 C---LDVDE-------CEAGDVCDNGICSNTPGSFQ 808
Score = 74.7 bits (182), Expect = 4e-13
Identities = 96/350 (27%), Positives = 130/350 (37%), Gaps = 66/350 (18%)
Query: 284 TRPPRRCDSNPCFRGVQCTDSR-----DGFQCGPCPEGYTGNGI-TCIDVDEC-KYHPCY 336
+RPP D + C C D + F+C C GY G C DV+EC + PC
Sbjct: 696 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCS 755
Query: 337 PGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVN 396
PG C NL FRC C G+ P G + C D+DEC G N IC N
Sbjct: 756 PG-WCENLPGSFRC-TCAQGYA-PAPDG----------RSCLDVDECEAGDVCDNGICSN 802
Query: 397 TLGSYRCGPCKPGYTGDQIRG-CKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
T GS++C C GY + R C+ C P + CI G C+C G
Sbjct: 803 TPGSFQC-QCLSGYHLSRDRSHCEDIDECDFP---AACIGGDCI-NTNGSYRCLCPQGHR 857
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDG 515
G +D+D + D L CK YV CDE G
Sbjct: 858 LVGGRKCQDID-ECSQDPSLCLPHGACKNLQGSYV--------------CVCDE---GFT 899
Query: 516 ILNEQDNCVLIHNVDQRNSDKDIFGDACDN--CLSVLNNDQKDTD-----GDGRGDACDD 568
+Q C V+Q + K+ + + D C SVL + + G G GD C+
Sbjct: 900 PTQDQHGC---EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCE- 955
Query: 569 DMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACD-SCPDVSNPNQSDVD 617
+ CP + + + DG G D + + P D+D
Sbjct: 956 ----------IYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Score = 62.0 bits (149), Expect = 3e-09
Identities = 45/131 (34%), Positives = 63/131 (48%), Gaps = 13/131 (9%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEG--YTGNGITCIDVDEC-KYHPCYPGVHCINLSPGF 348
S C G +C +++ G++C C +G Y GN + C+DVDEC C GV C N G+
Sbjct: 1002 SEICKEG-KCVNTQPGYECY-CKQGFYYDGNLLECVDVDECLDESNCRNGV-CENTRGGY 1058
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
RC P P + S +++ D+DEC++ A CVN GSYRC P
Sbjct: 1059 RCACTPPAEYSPAQRQ-----CLSPEEM--DVDECQDPAACRPGRCVNLPGSYRCECRPP 1111
Query: 409 GYTGDQIRGCK 419
G R C+
Sbjct: 1112 WVPGPSGRDCQ 1122
Score = 60.8 bits (146), Expect = 6e-09
Identities = 48/161 (29%), Positives = 62/161 (38%), Gaps = 31/161 (19%)
Query: 326 DVDECKYHP---CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
D+DEC C G C+N PG+ C C GF + N C D+DE
Sbjct: 993 DIDECMLFGSEICKEG-KCVNTQPGYEC-YCKQGF-----------YYDGNLLECVDVDE 1039
Query: 383 CRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE---LNPCSVNAQCI 439
C + + N +C NT G YRC C P A+R C +PE ++ C A C
Sbjct: 1040 CLDESNCRNGVCENTRGGYRCA-CTP-----PAEYSPAQRQCLSPEEMDVDECQDPAACR 1093
Query: 440 EER----QGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELP 476
R G C C W G+D + P E P
Sbjct: 1094 PGRCVNLPGSYRCECRPPWVPGP--SGRDCQLPESPAERAP 1132
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 22/102 (21%)
Query: 326 DVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN 385
D DEC+ C G C+ G C+ CP GF +++ C DIDECR
Sbjct: 1217 DSDECR---CVSG-RCVPRPGGAVCE-CPGGFQ-----------LDASRARCVDIDECRE 1260
Query: 386 ----GACVPNSICVNTLGSYRCGPCKPGYTGDQIRG-CKAER 422
G + CVNT GS+RC CK G+ + G C +R
Sbjct: 1261 LNQRGLLCKSERCVNTSGSFRC-VCKAGFARSRPHGACVPQR 1301
Score = 45.1 bits (105), Expect = 3e-04
Identities = 57/206 (27%), Positives = 75/206 (36%), Gaps = 38/206 (18%)
Query: 267 QSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCP-EGYTGNGITCI 325
+S PS + P P RPP + CF+ D+ CG P G T C
Sbjct: 251 ESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQ-----DTLPKQPCGSNPLPGLTKQEDCCG 305
Query: 326 DVD----ECKYHPC----YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVC 377
+ + K H C Y GV G CP G+ + N C
Sbjct: 306 SIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYK------------RLNSTHC 353
Query: 378 TDIDECRNGACVPNSICVNTLGSYRCGPCKPGYT-GDQIRGCKAERNCRNPELNPC---- 432
DI+EC + C+N GSYRC C PG++ G C A+ + E + C
Sbjct: 354 QDINECAMPGVCRHGDCLNNPGSYRC-VCPPGHSLGPSRTQCIAD---KPEEKSLCFRLV 409
Query: 433 SVNAQC---IEERQGDVTCVCGVGWA 455
S QC + R C C VG A
Sbjct: 410 SPEHQCQHPLTTRLTRQLCCCSVGKA 435
Score = 43.9 bits (102), Expect = 7e-04
Identities = 59/239 (24%), Positives = 86/239 (35%), Gaps = 49/239 (20%)
Query: 291 DSNPCFRGVQCTDSRDGFQCGPCPEG-YTGNGITCI-----DVDECKYHP-CYPGVHCIN 343
D + C GV C ++R G++C P Y+ C+ DVDEC+ C PG C+N
Sbjct: 1042 DESNCRNGV-CENTRGGYRCACTPPAEYSPAQRQCLSPEEMDVDECQDPAACRPG-RCVN 1099
Query: 344 LSPGFRCDACPVGFTGPMVQGVGI-----SFAKSNKQVCTDIDECRNGACV--------- 389
L +RC+ P GP + + A + VC +G C
Sbjct: 1100 LPGSYRCECRPPWVPGPSGRDCQLPESPAERAPERRDVCWS-QRGEDGMCAGPLAGPALT 1158
Query: 390 -PNSICVNTLG-SYRCGPCKPGYTGDQIRGCKAERN------------------CRNPEL 429
+ C G +C PC P G ++E N +
Sbjct: 1159 FDDCCCRQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDS 1218
Query: 430 NPC-SVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNC 487
+ C V+ +C+ R G C C G+ D + VDID EL CK + C
Sbjct: 1219 DECRCVSGRCV-PRPGGAVCECPGGFQLDA-SRARCVDIDEC--RELNQRGLLCKSERC 1273
>gi|18497288 latent transforming growth factor beta binding protein
3 isoform 2 [Homo sapiens]
Length = 1256
Score = 92.4 bits (228), Expect = 2e-18
Identities = 68/216 (31%), Positives = 93/216 (43%), Gaps = 37/216 (17%)
Query: 290 CDSNPCF--RGVQCTDSRDGFQCGPCPEGYT----GNGITCIDVDEC-KYHPCYPGVHCI 342
C++ PC RG+ C ++ + C C GY G +C+D++EC K H C G CI
Sbjct: 620 CEAEPCGPGRGI-CMNTGGSYNCH-CNRGYRLHVGAGGRSCVDLNECAKPHLCGDGGFCI 677
Query: 343 NLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYR 402
N ++C+ P G S VC DIDECR+ + P+ C N GS++
Sbjct: 678 NFPGHYKCNCYP-----------GYRLKASRPPVCEDIDECRDPSSCPDGKCENKPGSFK 726
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYI 460
C C+PGY C+ C E +PCS E G C C G+ A DG
Sbjct: 727 CIACQPGYRSQGGGACRDVNEC--AEGSPCSPG--WCENLPGSFRCTCAQGYAPAPDGRS 782
Query: 461 CGKDVDIDSYPDEELPCSARN-CKKDNCKYVPNSGQ 495
C +D+D C A + C C P S Q
Sbjct: 783 C---LDVDE-------CEAGDVCDNGICSNTPGSFQ 808
Score = 74.7 bits (182), Expect = 4e-13
Identities = 96/350 (27%), Positives = 130/350 (37%), Gaps = 66/350 (18%)
Query: 284 TRPPRRCDSNPCFRGVQCTDSR-----DGFQCGPCPEGYTGNGI-TCIDVDEC-KYHPCY 336
+RPP D + C C D + F+C C GY G C DV+EC + PC
Sbjct: 696 SRPPVCEDIDECRDPSSCPDGKCENKPGSFKCIACQPGYRSQGGGACRDVNECAEGSPCS 755
Query: 337 PGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVN 396
PG C NL FRC C G+ P G + C D+DEC G N IC N
Sbjct: 756 PG-WCENLPGSFRC-TCAQGYA-PAPDG----------RSCLDVDECEAGDVCDNGICSN 802
Query: 397 TLGSYRCGPCKPGYTGDQIRG-CKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA 455
T GS++C C GY + R C+ C P + CI G C+C G
Sbjct: 803 TPGSFQC-QCLSGYHLSRDRSHCEDIDECDFP---AACIGGDCI-NTNGSYRCLCPQGHR 857
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDG 515
G +D+D + D L CK YV CDE G
Sbjct: 858 LVGGRKCQDID-ECSQDPSLCLPHGACKNLQGSYV--------------CVCDE---GFT 899
Query: 516 ILNEQDNCVLIHNVDQRNSDKDIFGDACDN--CLSVLNNDQKDTD-----GDGRGDACDD 568
+Q C V+Q + K+ + + D C SVL + + G G GD C+
Sbjct: 900 PTQDQHGC---EEVEQPHHKKECYLNFDDTVFCDSVLATNVTQQECCCSLGAGWGDHCE- 955
Query: 569 DMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACD-SCPDVSNPNQSDVD 617
+ CP + + + DG G D + + P D+D
Sbjct: 956 ----------IYPCPVYSSAEFHSLCPDGKGYTQDNNIVNYGIPAHRDID 995
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/106 (33%), Positives = 45/106 (42%), Gaps = 22/106 (20%)
Query: 326 DVDECKYHP---CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
D+DEC C G C+N PG+ C C GF + N C D+DE
Sbjct: 993 DIDECMLFGSEICKEG-KCVNTQPGYEC-YCKQGF-----------YYDGNLLECVDVDE 1039
Query: 383 CRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPE 428
C + + N +C NT G YRC C P A+R C +PE
Sbjct: 1040 CLDESNCRNGVCENTRGGYRCA-CTP-----PAEYSPAQRQCLSPE 1079
Score = 45.8 bits (107), Expect = 2e-04
Identities = 35/102 (34%), Positives = 46/102 (45%), Gaps = 22/102 (21%)
Query: 326 DVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN 385
D DEC+ C G C+ G C+ CP GF +++ C DIDECR
Sbjct: 1170 DSDECR---CVSG-RCVPRPGGAVCE-CPGGFQ-----------LDASRARCVDIDECRE 1213
Query: 386 ----GACVPNSICVNTLGSYRCGPCKPGYTGDQIRG-CKAER 422
G + CVNT GS+RC CK G+ + G C +R
Sbjct: 1214 LNQRGLLCKSERCVNTSGSFRC-VCKAGFARSRPHGACVPQR 1254
Score = 45.4 bits (106), Expect = 2e-04
Identities = 59/233 (25%), Positives = 85/233 (36%), Gaps = 45/233 (19%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEG--YTGNGITCIDVDEC-KYHPCYPGVHCINLSPGF 348
S C G +C +++ G++C C +G Y GN + C+DVDEC C GV C N G+
Sbjct: 1002 SEICKEG-KCVNTQPGYECY-CKQGFYYDGNLLECVDVDECLDESNCRNGV-CENTRGGY 1058
Query: 349 RCDACPVGFTGP----MVQGVGISFAKSNKQVCTDIDECRNGACV----------PNSIC 394
RC P P + + A + VC +G C + C
Sbjct: 1059 RCACTPPAEYSPAQRQCLSPEEMERAPERRDVCWS-QRGEDGMCAGPLAGPALTFDDCCC 1117
Query: 395 VNTLG-SYRCGPCKPGYTGDQIRGCKAERN------------------CRNPELNPC-SV 434
G +C PC P G ++E N + + C V
Sbjct: 1118 RQGRGWGAQCRPCPPRGAGSHCPTSQSESNSFWDTSPLLLGKPPRDEDSSEEDSDECRCV 1177
Query: 435 NAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNC 487
+ +C+ R G C C G+ D + VDID EL CK + C
Sbjct: 1178 SGRCV-PRPGGAVCECPGGFQLDA-SRARCVDIDEC--RELNQRGLLCKSERC 1226
Score = 45.1 bits (105), Expect = 3e-04
Identities = 57/206 (27%), Positives = 75/206 (36%), Gaps = 38/206 (18%)
Query: 267 QSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCP-EGYTGNGITCI 325
+S PS + P P RPP + CF+ D+ CG P G T C
Sbjct: 251 ESAAPSQHLLPHPKPSHPRPPTQKPLGRCFQ-----DTLPKQPCGSNPLPGLTKQEDCCG 305
Query: 326 DVD----ECKYHPC----YPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVC 377
+ + K H C Y GV G CP G+ + N C
Sbjct: 306 SIGTAWGQSKCHKCPQLQYTGVQKPGPVRGEVGADCPQGYK------------RLNSTHC 353
Query: 378 TDIDECRNGACVPNSICVNTLGSYRCGPCKPGYT-GDQIRGCKAERNCRNPELNPC---- 432
DI+EC + C+N GSYRC C PG++ G C A+ + E + C
Sbjct: 354 QDINECAMPGVCRHGDCLNNPGSYRC-VCPPGHSLGPSRTQCIAD---KPEEKSLCFRLV 409
Query: 433 SVNAQC---IEERQGDVTCVCGVGWA 455
S QC + R C C VG A
Sbjct: 410 SPEHQCQHPLTTRLTRQLCCCSVGKA 435
>gi|66346695 fibrillin 2 precursor [Homo sapiens]
Length = 2912
Score = 91.3 bits (225), Expect = 4e-18
Identities = 102/355 (28%), Positives = 149/355 (41%), Gaps = 61/355 (17%)
Query: 290 CDSNPCF-RGVQCTDSRDGFQCGPCPEGYTGNGI--TCIDVDECKYHP--CYPGVHCINL 344
C++NP G QCT+ ++C C +G+ + TCIDV+EC + C G C N
Sbjct: 1287 CENNPDICDGGQCTNIPGEYRC-LCYDGFMASMDMKTCIDVNECDLNSNICMFG-ECENT 1344
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA--CVPNSICVNTLGSYR 402
F C C +G++ K CTD+DEC GA C ++ C+N GS++
Sbjct: 1345 KGSFICH-CQLGYS-----------VKKGTTGCTDVDECEIGAHNCDMHASCLNIPGSFK 1392
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
C C+ G+ G+ I+ C C N + CS+NAQC+ G C C G+ GDG+ C
Sbjct: 1393 CS-CREGWIGNGIK-CIDLDECSN-GTHQCSINAQCV-NTPGSYRCACSEGFTGDGFTC- 1447
Query: 463 KDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGD-GILNEQD 521
DVD E + C+ C VP + + + + G A D + D + Q+
Sbjct: 1448 SDVD-------ECAENINLCENGQCLNVPGAYRCECEM-GFTPASDSRSCQDIDECSFQN 1499
Query: 522 NCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDN 581
CV N+ +F CD D + D G G+ D D D I +
Sbjct: 1500 ICVF----GTCNNLPGMFHCICD--------DGYELDRTG-GNCTDIDECADPINCVNGL 1546
Query: 582 CPKFPNRDQRDKDGDGVGDACDSCPDVS-NPNQSDVDNDLVGDSCDTNQDSDGDG 635
C P R + C+ PD NP ++ VG +C GDG
Sbjct: 1547 CVNTPGRYE-----------CNCPPDFQLNPTGVGCVDNRVG-NCYLKFGPRGDG 1589
Score = 82.4 bits (202), Expect = 2e-15
Identities = 63/207 (30%), Positives = 91/207 (43%), Gaps = 33/207 (15%)
Query: 290 CDSNPCFRGVQ--CTDSRDGFQCGPCPEGYT--GNGITCIDVDECK-YHPCYPGVHCINL 344
C S P G + C ++ F C C G++ G+ C DVDEC H C G C N+
Sbjct: 2575 CGSQPSLCGAKGICQNTPGSFSC-ECQRGFSLDATGLNCEDVDECDGNHRCQHG--CQNI 2631
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCG 404
G+RC CP G+ I + N+ C D +EC N ++ C NTLGSY+C
Sbjct: 2632 LGGYRC-GCPQGY---------IQHYQWNQ--CVDENECSNPNACGSASCYNTLGSYKCA 2679
Query: 405 PCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW---------A 455
C G++ DQ + N + NPC+ +G C C G+ +
Sbjct: 2680 -CPSGFSFDQFSSACHDVNECSSSKNPCNYGC---SNTEGGYLCGCPPGYYRVGQGHCVS 2735
Query: 456 GDGYICGKDVDIDSYPDEELPCSARNC 482
G G+ G+ + +D+ DEE S C
Sbjct: 2736 GMGFNKGQYLSLDTEVDEENALSPEAC 2762
Score = 77.0 bits (188), Expect = 8e-14
Identities = 66/182 (36%), Positives = 83/182 (45%), Gaps = 30/182 (16%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
+N C G +C + ++C C GY NG CIDVDEC +PC G C+N +
Sbjct: 502 ANLCLNG-RCIPTVSSYRC-ECNMGYKQDANG-DCIDVDECTSNPCTNG-DCVNTPGSYY 557
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPCKP 408
C C GF KQ C DIDEC +NG N CVNT GS++C C
Sbjct: 558 C-KCHAGFQ-----------RTPTKQACIDIDECIQNGVLCKNGRCVNTDGSFQC-ICNA 604
Query: 409 GY--TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYICGKD 464
G+ T D + C C N C +N CI E G C+C G+ A +G C D
Sbjct: 605 GFELTTDG-KNCVDHDECTT--TNMC-LNGMCINE-DGSFKCICKPGFVLAPNGRYC-TD 658
Query: 465 VD 466
VD
Sbjct: 659 VD 660
Score = 76.6 bits (187), Expect = 1e-13
Identities = 60/203 (29%), Positives = 86/203 (42%), Gaps = 46/203 (22%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDEC--KYHPCYPGVHCINLSPGFR 349
++ C QC ++ ++C C EG+TG+G TC DVDEC + C G C+N+ +R
Sbjct: 1416 THQCSINAQCVNTPGSYRCA-CSEGFTGDGFTCSDVDECAENINLCENG-QCLNVPGAYR 1473
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C+ C +GFT S+ + C DIDEC C N G + C C G
Sbjct: 1474 CE-CEMGFT-----------PASDSRSCQDIDECSFQNICVFGTCNNLPGMFHC-ICDDG 1520
Query: 410 YTGDQIRG-------CKAERNCRNP-----------------ELNPCSVNAQCIEERQGD 445
Y D+ G C NC N +LNP V C++ R G+
Sbjct: 1521 YELDRTGGNCTDIDECADPINCVNGLCVNTPGRYECNCPPDFQLNPTGVG--CVDNRVGN 1578
Query: 446 VTCVCGVGWAGDGYI-CGKDVDI 467
C G GDG + C ++ +
Sbjct: 1579 --CYLKFGPRGDGSLSCNTEIGV 1599
Score = 76.6 bits (187), Expect = 1e-13
Identities = 68/194 (35%), Positives = 87/194 (44%), Gaps = 35/194 (18%)
Query: 310 CGPCPEGYTGNGIT--CIDVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGV 365
CG P G+T + T +D+DECK P C GV CIN FRC+ CP GF+
Sbjct: 1791 CGNIP-GFTFDIHTGKAVDIDECKEIPGICANGV-CINQIGSFRCE-CPTGFS------- 1840
Query: 366 GISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERN 423
VC DIDEC NG C N+ C+N+ GSYRC C G+ C
Sbjct: 1841 ----YNDLLLVCEDIDECSNGDNLCQRNADCINSPGSYRC-ECAAGFKLSPNGACVDRNE 1895
Query: 424 CRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYICGKDVDIDSYPDEELPCSARN 481
C N CS + C+ + QG C+C G+ + D +C +D+D E PC
Sbjct: 1896 CLEIP-NVCS-HGLCV-DLQGSYQCICHNGFKASQDQTMC---MDVDEC--ERHPCGNGT 1947
Query: 482 CKKD----NCKYVP 491
CK NC P
Sbjct: 1948 CKNTVGSYNCLCYP 1961
Score = 74.7 bits (182), Expect = 4e-13
Identities = 58/193 (30%), Positives = 86/193 (44%), Gaps = 29/193 (15%)
Query: 289 RCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGI---TCIDVDECKYHP--CYPGVHCIN 343
R + C G+ C ++ F+C C EGY + C+D+DEC+ +P C G C+N
Sbjct: 1120 RISPDLCGSGI-CVNTPGSFEC-ECFEGYESGFMMMKNCMDIDECERNPLLCRGGT-CVN 1176
Query: 344 LSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYR 402
F+CD CP+G +++ C DI+EC + N CVN +G+Y+
Sbjct: 1177 TEGSFQCD-CPLGHE-----------LSPSREDCVDINECSLSDNLCRNGKCVNMIGTYQ 1224
Query: 403 CGPCKPGYTGDQIR-GCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWA--GDGY 459
C C PGY R GC C + + QC +G C C G+A DG
Sbjct: 1225 CS-CNPGYQATPDRQGCTDIDECM---IMNGGCDTQCTNS-EGSYECSCSEGYALMPDGR 1279
Query: 460 ICGKDVDIDSYPD 472
C + ++ PD
Sbjct: 1280 SCADIDECENNPD 1292
Score = 71.2 bits (173), Expect = 4e-12
Identities = 57/184 (30%), Positives = 76/184 (41%), Gaps = 29/184 (15%)
Query: 283 PTRPPRRCDSNPCFRGV------QCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKY-H 333
P+ R D N C QC ++ F+C CP GY + G+ C+D DEC +
Sbjct: 2163 PSLHDTREDVNECLESPGICSNGQCINTDGSFRC-ECPMGYNLDYTGVRCVDTDECSIGN 2221
Query: 334 PCYPGVHCINLSPGFRCDACPVGF-TGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNS 392
PC G C N+ F C+ C GF GPM+ C DI+EC +
Sbjct: 2222 PCGNGT-CTNVIGSFECN-CNEGFEPGPMMN-------------CEDINECAQNPLLCAF 2266
Query: 393 ICVNTLGSYRCGPCKPGYT-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCG 451
C+NT GSY C C GY + + CK C L+ C + G C+C
Sbjct: 2267 RCMNTFGSYEC-TCPIGYALREDQKMCKDLDECAE-GLHDCESRGMMCKNLIGTFMCICP 2324
Query: 452 VGWA 455
G A
Sbjct: 2325 PGMA 2328
Score = 68.2 bits (165), Expect = 4e-11
Identities = 56/184 (30%), Positives = 82/184 (44%), Gaps = 33/184 (17%)
Query: 290 CDSNPCF-RGVQCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKYHP--CYPGVHCINL 344
C+ NP RG C ++ FQC CP G+ + + C+D++EC C G C+N+
Sbjct: 1162 CERNPLLCRGGTCVNTEGSFQCD-CPLGHELSPSREDCVDINECSLSDNLCRNG-KCVNM 1219
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGACVPNSICVNTLGSYR 402
++C +C G+ A ++Q CTDIDEC NG C ++ C N+ GSY
Sbjct: 1220 IGTYQC-SCNPGYQ-----------ATPDRQGCTDIDECMIMNGGC--DTQCTNSEGSYE 1265
Query: 403 CGPCKPGYT-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
C C GY R C C N NP + G+ C+C DG++
Sbjct: 1266 CS-CSEGYALMPDGRSCADIDECEN---NPDICDGGQCTNIPGEYRCLC-----YDGFMA 1316
Query: 462 GKDV 465
D+
Sbjct: 1317 SMDM 1320
Score = 68.2 bits (165), Expect = 4e-11
Identities = 49/167 (29%), Positives = 74/167 (44%), Gaps = 23/167 (13%)
Query: 293 NPCFRGVQCTDSRDGFQCGPCPEGYT-GNGITCIDVDECKYHPCYPGVHCINLSPGFRCD 351
NPC G CT+ F+C C EG+ G + C D++EC +P C+N + C
Sbjct: 2221 NPCGNGT-CTNVIGSFECN-CNEGFEPGPMMNCEDINECAQNPLLCAFRCMNTFGSYEC- 2277
Query: 352 ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNS---ICVNTLGSYRCGPCKP 408
CP+G+ + ++++C D+DEC G S +C N +G++ C C P
Sbjct: 2278 TCPIGYA-----------LREDQKMCKDLDECAEGLHDCESRGMMCKNLIGTFMC-ICPP 2325
Query: 409 GYT-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
G GC E CR + C N +C+ G C C G+
Sbjct: 2326 GMARRPDGEGCVDENECRT-KPGICE-NGRCV-NIIGSYRCECNEGF 2369
Score = 68.2 bits (165), Expect = 4e-11
Identities = 72/238 (30%), Positives = 91/238 (38%), Gaps = 49/238 (20%)
Query: 307 GFQCGPCP--------------EGYTGNGITCIDVDECKYHP--CYPGVHCINLSPGFRC 350
G QC CP GYT +G D+DECK P C G CIN FRC
Sbjct: 2419 GHQCELCPLPGTAQYKKICPHGPGYTTDGR---DIDECKVMPNLCTNG-QCINTMGSFRC 2474
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGY 410
C VG+T + G C D+DEC N IC NT GSY+C C GY
Sbjct: 2475 -FCKVGYTTD-ISGTS----------CIDLDECSQSPKPCNYICKNTEGSYQCS-CPRGY 2521
Query: 411 T-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDS 469
+ + CK C+ + N C+ G TC C G+ C + + S
Sbjct: 2522 VLQEDGKTCKDLDECQTKQHN---CQFLCV-NTLGGFTCKCPPGFTQHHTACIDNNECGS 2577
Query: 470 YPDEELPCSARNCKKDNCKYVPNSGQEDADR----DGIGDACDEDADGDGILNEQDNC 523
P C A K C+ P S + R D G C++ + DG Q C
Sbjct: 2578 QPS---LCGA----KGICQNTPGSFSCECQRGFSLDATGLNCEDVDECDGNHRCQHGC 2628
Score = 66.2 bits (160), Expect = 1e-10
Identities = 55/196 (28%), Positives = 80/196 (40%), Gaps = 30/196 (15%)
Query: 293 NPCFRGVQCTDSRDGFQCGPCPEGYTGNG--ITCIDVDECKYHPCYPGVHCINLSPGFRC 350
N C G+ C D + +QC C G+ + C+DVDEC+ HPC G C N + C
Sbjct: 1901 NVCSHGL-CVDLQGSYQC-ICHNGFKASQDQTMCMDVDECERHPCGNGT-CKNTVGSYNC 1957
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRCGPCKP 408
P F ++ C DIDEC + G N C N +GS++C C
Sbjct: 1958 LCYP-------------GFELTHNNDCLDIDECSSFFGQVCRNGRCFNEIGSFKC-LCNE 2003
Query: 409 GY--TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
GY T D + C C P S + + +G C+C G+ C +D
Sbjct: 2004 GYELTPDG-KNCIDTNEC---VALPGSCSPGTCQNLEGSFRCICPPGYEVKSENC---ID 2056
Query: 467 IDSYPDEELPCSARNC 482
I+ ++ C +C
Sbjct: 2057 INECDEDPNICLFGSC 2072
Score = 62.4 bits (150), Expect = 2e-09
Identities = 40/113 (35%), Positives = 55/113 (48%), Gaps = 18/113 (15%)
Query: 300 QCTDSRDGFQCGPCPEGY--TGNGITCIDVDECKY-HPCYPGVHCINLSPGFRCDACPVG 356
+C ++ FQC C G+ T +G C+D DEC + C G+ CIN F+C C G
Sbjct: 590 RCVNTDGSFQC-ICNAGFELTTDGKNCVDHDECTTTNMCLNGM-CINEDGSFKC-ICKPG 646
Query: 357 FTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
F N + CTD+DEC+ N C+N+ GS+RC C PG
Sbjct: 647 FV-----------LAPNGRYCTDVDECQTPGICMNGHCINSEGSFRC-DCPPG 687
Score = 61.2 bits (147), Expect = 4e-09
Identities = 46/145 (31%), Positives = 63/145 (43%), Gaps = 23/145 (15%)
Query: 326 DVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
DV+EC P C G CIN FRC+ CP+G+ + G+ C D DEC
Sbjct: 2171 DVNECLESPGICSNG-QCINTDGSFRCE-CPMGYN---LDYTGVR--------CVDTDEC 2217
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQ 443
G N C N +GS+ C C G+ + C+ C NP +C+
Sbjct: 2218 SIGNPCGNGTCTNVIGSFECN-CNEGFEPGPMMNCEDINECAQ---NPLLCAFRCM-NTF 2272
Query: 444 GDVTCVCGVGWA--GDGYICGKDVD 466
G C C +G+A D +C KD+D
Sbjct: 2273 GSYECTCPIGYALREDQKMC-KDLD 2296
Score = 55.8 bits (133), Expect = 2e-07
Identities = 71/262 (27%), Positives = 91/262 (34%), Gaps = 58/262 (22%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVH-------------- 340
C G C +S F+C CP G + VD CY G+
Sbjct: 668 CMNG-HCINSEGSFRCD-CPPGLAVGMDGRVCVDTHMRSTCYGGIKKGVCVRPFPGAVTK 725
Query: 341 ----CINLSPGFR--CDACPVG----FTGPMVQGVGISFAKSNKQVCT-DIDECRNGACV 389
C N GF C CP F G GVGI+ + C D D C NG
Sbjct: 726 SECCCANPDYGFGEPCQPCPAKNSAEFHGLCSSGVGITVDGRDINECALDPDICANG--- 782
Query: 390 PNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIE-----ERQG 444
IC N GSYRC C GY D + RNC +++ C VN + G
Sbjct: 783 ---ICENLRGSYRCN-CNSGYEPD-----ASGRNC--IDIDECLVNRLLCDNGLCRNTPG 831
Query: 445 DVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKD----NCKYVPNSGQEDADR 500
+C C G+ + + D E PC C+ + NC+ P S
Sbjct: 832 SYSCTCPPGYV---FRTETETCEDINECESNPCVNGACRNNLGSFNCECSPGS-----KL 883
Query: 501 DGIGDACDEDADGDGILNEQDN 522
G C + G LN QD+
Sbjct: 884 SSTGLICIDSLKGTCWLNIQDS 905
Score = 53.5 bits (127), Expect = 9e-07
Identities = 51/184 (27%), Positives = 76/184 (41%), Gaps = 26/184 (14%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYT--GNGITCIDVDECKYHPCYPGVHCINLSPGFRCDA 352
C G+ C ++ + C CP GY TC D++EC+ +PC G C N F C+
Sbjct: 821 CDNGL-CRNTPGSYSC-TCPPGYVFRTETETCEDINECESNPCVNGA-CRNNLGSFNCEC 877
Query: 353 CPVGFTGPMVQGVGISFAKSNKQVC-TDIDECR-----NGACVPNSICVNTLGSYRCGPC 406
P G + G+ S K C +I + R NGA + + C TLG+ PC
Sbjct: 878 SP----GSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGATLKSECCA-TLGAAWGSPC 932
Query: 407 KPGYTGDQI-RGCKAERNCRNPELNPCSV------NAQCIEERQGDVTCVC--GVGWAGD 457
+ RG + ++N C V N +C+ + G C C G+ G
Sbjct: 933 ERCELDTACPRGLARIKGVTCEDVNECEVFPGVCPNGRCVNSK-GSFHCECPEGLTLDGT 991
Query: 458 GYIC 461
G +C
Sbjct: 992 GRVC 995
Score = 51.2 bits (121), Expect = 5e-06
Identities = 45/134 (33%), Positives = 56/134 (41%), Gaps = 24/134 (17%)
Query: 326 DVDECKYHP--CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
D++ECK P C G C N F+C C GF M ++ CTDIDEC
Sbjct: 1073 DINECKAFPGMCTYG-KCRNTIGSFKC-RCNSGFALDM-----------EERNCTDIDEC 1119
Query: 384 RNGACVPNS-ICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRN---PELNPCSVNAQCI 439
R + S ICVNT GS+ C C GY G +NC + E NP
Sbjct: 1120 RISPDLCGSGICVNTPGSFEC-ECFEGYES----GFMMMKNCMDIDECERNPLLCRGGTC 1174
Query: 440 EERQGDVTCVCGVG 453
+G C C +G
Sbjct: 1175 VNTEGSFQCDCPLG 1188
Score = 50.4 bits (119), Expect = 8e-06
Identities = 57/207 (27%), Positives = 77/207 (37%), Gaps = 53/207 (25%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCP-EGYTGNGITCIDV-----------DECKYH---- 333
C+SNPC G C ++ F C P + G+ CID C+ +
Sbjct: 856 CESNPCVNGA-CRNNLGSFNCECSPGSKLSSTGLICIDSLKGTCWLNIQDSRCEVNINGA 914
Query: 334 ----PCYPGVHCINLSPGFRCD---ACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR-- 384
C + SP RC+ ACP G ++GV C D++EC
Sbjct: 915 TLKSECCATLGAAWGSPCERCELDTACPRGLA--RIKGV----------TCEDVNECEVF 962
Query: 385 NGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSV---NAQCIEE 441
G C PN CVN+ GS+ C C G T D R C + + C + +CI
Sbjct: 963 PGVC-PNGRCVNSKGSFHC-ECPEGLTLD-----GTGRVCLDIRMEQCYLKWDEDECIHP 1015
Query: 442 RQGDV---TCVCGVG--WAGDGYICGK 463
G C C VG W + C K
Sbjct: 1016 VPGKFRMDACCCAVGAAWGTECEECPK 1042
Score = 40.8 bits (94), Expect = 0.006
Identities = 50/191 (26%), Positives = 72/191 (37%), Gaps = 41/191 (21%)
Query: 287 PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGN-------GITCIDVDECKYHPCYPGV 339
P RC F G QC RD ++ GPC GI C C
Sbjct: 193 PNRCACVYGFTGPQC--ERD-YRTGPCFTQVNNQMCQGQLTGIVCTKTLCCA-------- 241
Query: 340 HCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNT 397
I + G C+ CP P +G C D+DEC+ G C + C+NT
Sbjct: 242 -TIGRAWGHPCEMCPAQ-PQPCRRGF---IPNIRTGACQDVDECQAIPGICQGGN-CINT 295
Query: 398 LGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQ-----GDVTCVCGV 452
+GS+ C C G+ ++E + +++ CS+ E + G CVC
Sbjct: 296 VGSFEC-RCPAGHK-------QSETTQKCEDIDECSIIPGICETGECSNTVGSYFCVCPR 347
Query: 453 GW--AGDGYIC 461
G+ + DG C
Sbjct: 348 GYVTSTDGSRC 358
Score = 36.6 bits (83), Expect = 0.12
Identities = 46/184 (25%), Positives = 69/184 (37%), Gaps = 34/184 (18%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCID--VDEC--KYHPCYPGVHCINLSPGF 348
C G+ C ++ ++C CP + N G+ C+D V C K+ P G N G
Sbjct: 1542 CVNGL-CVNTPGRYECN-CPPDFQLNPTGVGCVDNRVGNCYLKFGPRGDGSLSCNTEIGV 1599
Query: 349 R-----------------CDACP-VGFTGPMVQGVGISFAKSNKQ--VCTDIDECRN--G 386
C+ CP V T G + N + DIDEC+ G
Sbjct: 1600 GVSRSSCCCSLGKAWGNPCETCPPVNSTEYYTLCPGGEGFRPNPITIILEDIDECQELPG 1659
Query: 387 ACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDV 446
C + C+NT GS++C + Y + R C+ C +P G+
Sbjct: 1660 LCQGGN-CINTFGSFQCECPQGYYLSEDTRICEDIDEC---FAHPGVCGPGTCYNTLGNY 1715
Query: 447 TCVC 450
TC+C
Sbjct: 1716 TCIC 1719
>gi|46249414 latent transforming growth factor beta binding protein 1
isoform LTBP-1L [Homo sapiens]
Length = 1722
Score = 88.6 bits (218), Expect = 3e-17
Identities = 73/270 (27%), Positives = 110/270 (40%), Gaps = 33/270 (12%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTG 359
QC +S +QC PC EG+ G C+DVDEC C NL + C +C G+T
Sbjct: 1013 QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMC-SCHKGYT- 1070
Query: 360 PMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRG-C 418
+ + C DIDEC+ G N C NT GS+RC C GY + C
Sbjct: 1071 ----------RTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC-TCGQGYQLSAAKDQC 1119
Query: 419 KAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCS 478
+ C++ L + QC +G CVC G+ G + DI+ +++ C
Sbjct: 1120 EDIDECQHRHL---CAHGQC-RNTEGSFQCVCDQGYRASG-LGDHCEDINECLEDKSVCQ 1174
Query: 479 ARNCKKDNCKY---VPNSGQEDADRDGIGDACDE--DADGDGILNEQDNCV----LIHNV 529
+C Y P+ Q D ++ C + + + G+ Q C+ H V
Sbjct: 1175 RGDCINTAGSYDCTCPDGFQLDDNK-----TCQDINECEHPGLCGPQGECLNTEGSFHCV 1229
Query: 530 DQRNSDKDIFGDACDNCLSVLNNDQKDTDG 559
Q+ G C++ +NN D+ G
Sbjct: 1230 CQQGFSISADGRTCEDIDECVNNTVCDSHG 1259
Score = 85.1 bits (209), Expect = 3e-16
Identities = 72/260 (27%), Positives = 99/260 (38%), Gaps = 69/260 (26%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKYHPCYPGVHCINLSPGFRCDA 352
C +G +C ++ F C CP G+ + G CIDVDEC HC+N FRC+
Sbjct: 927 CSQG-RCENTEGSFLC-ICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY 984
Query: 353 CPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTG 412
C G+ + + C DIDEC N + P+ CVN+ GSY+C PC G+ G
Sbjct: 985 CDSGYR------------MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRG 1032
Query: 413 ----------------------DQIRG---CKAERN-CRNPELNPC-----------SVN 435
+ G C + R P+ C VN
Sbjct: 1033 WNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN 1092
Query: 436 AQCIEERQGDVTCVCGVGWAGDGYICGKD--VDIDSYPDEELPCSARNCKKDNCKYVPNS 493
QC + +G C CG G+ KD DID L C C+ S
Sbjct: 1093 GQC-KNTEGSFRCTCGQGYQ---LSAAKDQCEDIDECQHRHL------CAHGQCRNTEGS 1142
Query: 494 GQEDADR----DGIGDACDE 509
Q D+ G+GD C++
Sbjct: 1143 FQCVCDQGYRASGLGDHCED 1162
Score = 75.1 bits (183), Expect = 3e-13
Identities = 88/339 (25%), Positives = 124/339 (36%), Gaps = 84/339 (24%)
Query: 291 DSNPCFRGVQCTDSRDGFQCGPCPEGYT-GNGITCIDVDECKYHP--CYPGVHCINLSPG 347
D + C RG C ++ + C CP+G+ + TC D++EC+ HP C P C+N
Sbjct: 1169 DKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGS 1225
Query: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPC 406
F C C GF+ ++ + C DIDEC N C + C NT GS+RC C
Sbjct: 1226 FHC-VCQQGFS-----------ISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC-LC 1272
Query: 407 KPGYTGDQI-RGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDV 465
G+ Q +GC C EL E +G CVC
Sbjct: 1273 YQGFQAPQDGQGCVDVNEC---ELLSGVCGEAFCENVEGSFLCVCA-------------- 1315
Query: 466 DIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL 525
+N +Y P +GQ + + D D D D E+ C
Sbjct: 1316 ------------------DENQEYSPMTGQCRS-----RTSTDLDVDVDQPKEEKKEC-- 1350
Query: 526 IHNVDQRNSDKDIFGDACDNCL--SVLNNDQKDTDGDGRGDACD-DDMDGDGIKNILDNC 582
+N++ CDN L +V + T G G GD C+ G + C
Sbjct: 1351 YYNLND--------ASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMC 1402
Query: 583 PKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLV 621
PK G G A +S + N D D L+
Sbjct: 1403 PK----------GKGFVPAGESSSEAGGENYKDADECLL 1431
Score = 73.6 bits (179), Expect = 9e-13
Identities = 70/240 (29%), Positives = 93/240 (38%), Gaps = 36/240 (15%)
Query: 265 KFQSPTPSTVVPPAPPAP------PTRPPR--RCDSNPCFRGV-QCTDSRDGFQCGPCPE 315
K P P V P A + PT+ C NP G C + + C C E
Sbjct: 845 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTC-ICYE 903
Query: 316 GY--TGNGITCIDVDECK--YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAK 371
GY + C+D+DEC H C G C N F C CP GF A
Sbjct: 904 GYRFSEQQRKCVDIDECTQVQHLCSQG-RCENTEGSFLC-ICPAGF-----------MAS 950
Query: 372 SNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNP 431
C D+DEC CVNT+G++RC C GY Q C+ C NP P
Sbjct: 951 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCP 1010
Query: 432 CSVNAQCIEERQGDVTCV-CGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV 490
+ QC+ G CV C G+ G G+ +D+D + + C+ +C Y+
Sbjct: 1011 ---DEQCVNS-PGSYQCVPCTEGFRGWN---GQCLDVDECLEPNV-CANGDCSNLEGSYM 1062
Score = 54.3 bits (129), Expect = 5e-07
Identities = 48/170 (28%), Positives = 65/170 (38%), Gaps = 32/170 (18%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDV------DECKYHPCYPGVHCINLSPGFRCDAC 353
+C G QCG G + C V ++C+ P P H N + C
Sbjct: 558 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYN-----QMMEC 612
Query: 354 PVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGD 413
G+ + N C DI+EC+ PN C+NT+GSYRC CK G+ D
Sbjct: 613 LPGYK------------RVNNTFCQDINECQLQGVCPNGECLNTMGSYRC-TCKIGFGPD 659
Query: 414 -QIRGCKAERNCRNPELNPC----SVNAQCIEERQGDVT---CVCGVGWA 455
C + + E PC S QC+ +T C C VG A
Sbjct: 660 PTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKA 709
Score = 40.4 bits (93), Expect = 0.008
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 326 DVDECKYHP---CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
D DEC C G C+N PG+ C + P+ K C D+DE
Sbjct: 1425 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPV------------KLQCFDMDE 1471
Query: 383 CRNGACVPNSICVNTLGSYRC 403
C++ + + CVNT GSY C
Sbjct: 1472 CQDPSSCIDGQCVNTEGSYNC 1492
Score = 40.4 bits (93), Expect = 0.008
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 19/96 (19%)
Query: 320 NGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTD 379
N + +EC C+ + G+ CD C G+ + K C D
Sbjct: 1616 NSFEELQAEECGILNGCENGRCVRVQEGYTCD-CFDGY-----------HLDTAKMTCVD 1663
Query: 380 IDEC-----RNGACVPNSICVNTLGSYRCGPCKPGY 410
++EC R C N+ C+NT GSY+C C PGY
Sbjct: 1664 VNECDELNNRMSLC-KNAKCINTDGSYKC-LCLPGY 1697
Score = 34.3 bits (77), Expect = 0.57
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 333 HPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR-NGACVPN 391
HP +PG+ SP + P T Q + + QV T+I+EC N
Sbjct: 835 HPQFPGIVIEKTSPPVPVEVAPEASTSSASQVI------APTQV-TEINECTVNPDICGA 887
Query: 392 SICVNTLGSYRCGPCKPGYT-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVC 450
C+N Y C C GY +Q R C C + + CS +C E +G C+C
Sbjct: 888 GHCINLPVRYTC-ICYEGYRFSEQQRKCVDIDECTQVQ-HLCS-QGRC-ENTEGSFLCIC 943
Query: 451 GVGW--AGDGYICGKDVDID 468
G+ + +G C +D+D
Sbjct: 944 PAGFMASEEGTNC---IDVD 960
>gi|46249412 latent transforming growth factor beta binding protein
1 isoform LTBP-1S [Homo sapiens]
Length = 1396
Score = 88.6 bits (218), Expect = 3e-17
Identities = 73/270 (27%), Positives = 110/270 (40%), Gaps = 33/270 (12%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTG 359
QC +S +QC PC EG+ G C+DVDEC C NL + C +C G+T
Sbjct: 687 QCVNSPGSYQCVPCTEGFRGWNGQCLDVDECLEPNVCANGDCSNLEGSYMC-SCHKGYT- 744
Query: 360 PMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRG-C 418
+ + C DIDEC+ G N C NT GS+RC C GY + C
Sbjct: 745 ----------RTPDHKHCRDIDECQQGNLCVNGQCKNTEGSFRC-TCGQGYQLSAAKDQC 793
Query: 419 KAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCS 478
+ C++ L + QC +G CVC G+ G + DI+ +++ C
Sbjct: 794 EDIDECQHRHL---CAHGQC-RNTEGSFQCVCDQGYRASG-LGDHCEDINECLEDKSVCQ 848
Query: 479 ARNCKKDNCKY---VPNSGQEDADRDGIGDACDE--DADGDGILNEQDNCV----LIHNV 529
+C Y P+ Q D ++ C + + + G+ Q C+ H V
Sbjct: 849 RGDCINTAGSYDCTCPDGFQLDDNK-----TCQDINECEHPGLCGPQGECLNTEGSFHCV 903
Query: 530 DQRNSDKDIFGDACDNCLSVLNNDQKDTDG 559
Q+ G C++ +NN D+ G
Sbjct: 904 CQQGFSISADGRTCEDIDECVNNTVCDSHG 933
Score = 85.1 bits (209), Expect = 3e-16
Identities = 72/260 (27%), Positives = 99/260 (38%), Gaps = 69/260 (26%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECKYHPCYPGVHCINLSPGFRCDA 352
C +G +C ++ F C CP G+ + G CIDVDEC HC+N FRC+
Sbjct: 601 CSQG-RCENTEGSFLC-ICPAGFMASEEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEY 658
Query: 353 CPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTG 412
C G+ + + C DIDEC N + P+ CVN+ GSY+C PC G+ G
Sbjct: 659 CDSGYR------------MTQRGRCEDIDECLNPSTCPDEQCVNSPGSYQCVPCTEGFRG 706
Query: 413 ----------------------DQIRG---CKAERN-CRNPELNPC-----------SVN 435
+ G C + R P+ C VN
Sbjct: 707 WNGQCLDVDECLEPNVCANGDCSNLEGSYMCSCHKGYTRTPDHKHCRDIDECQQGNLCVN 766
Query: 436 AQCIEERQGDVTCVCGVGWAGDGYICGKD--VDIDSYPDEELPCSARNCKKDNCKYVPNS 493
QC + +G C CG G+ KD DID L C C+ S
Sbjct: 767 GQC-KNTEGSFRCTCGQGYQ---LSAAKDQCEDIDECQHRHL------CAHGQCRNTEGS 816
Query: 494 GQEDADR----DGIGDACDE 509
Q D+ G+GD C++
Sbjct: 817 FQCVCDQGYRASGLGDHCED 836
Score = 75.1 bits (183), Expect = 3e-13
Identities = 88/339 (25%), Positives = 124/339 (36%), Gaps = 84/339 (24%)
Query: 291 DSNPCFRGVQCTDSRDGFQCGPCPEGYT-GNGITCIDVDECKYHP--CYPGVHCINLSPG 347
D + C RG C ++ + C CP+G+ + TC D++EC+ HP C P C+N
Sbjct: 843 DKSVCQRG-DCINTAGSYDC-TCPDGFQLDDNKTCQDINECE-HPGLCGPQGECLNTEGS 899
Query: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC-RNGACVPNSICVNTLGSYRCGPC 406
F C C GF+ ++ + C DIDEC N C + C NT GS+RC C
Sbjct: 900 FHC-VCQQGFS-----------ISADGRTCEDIDECVNNTVCDSHGFCDNTAGSFRC-LC 946
Query: 407 KPGYTGDQI-RGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDV 465
G+ Q +GC C EL E +G CVC
Sbjct: 947 YQGFQAPQDGQGCVDVNEC---ELLSGVCGEAFCENVEGSFLCVCA-------------- 989
Query: 466 DIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL 525
+N +Y P +GQ + + D D D D E+ C
Sbjct: 990 ------------------DENQEYSPMTGQCRS-----RTSTDLDVDVDQPKEEKKEC-- 1024
Query: 526 IHNVDQRNSDKDIFGDACDNCL--SVLNNDQKDTDGDGRGDACD-DDMDGDGIKNILDNC 582
+N++ CDN L +V + T G G GD C+ G + C
Sbjct: 1025 YYNLND--------ASLCDNVLAPNVTKQECCCTSGAGWGDNCEIFPCPVLGTAEFTEMC 1076
Query: 583 PKFPNRDQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLV 621
PK G G A +S + N D D L+
Sbjct: 1077 PK----------GKGFVPAGESSSEAGGENYKDADECLL 1105
Score = 73.6 bits (179), Expect = 9e-13
Identities = 70/240 (29%), Positives = 93/240 (38%), Gaps = 36/240 (15%)
Query: 265 KFQSPTPSTVVPPAPPAP------PTRPPR--RCDSNPCFRGV-QCTDSRDGFQCGPCPE 315
K P P V P A + PT+ C NP G C + + C C E
Sbjct: 519 KTSPPVPVEVAPEASTSSASQVIAPTQVTEINECTVNPDICGAGHCINLPVRYTC-ICYE 577
Query: 316 GY--TGNGITCIDVDECK--YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAK 371
GY + C+D+DEC H C G C N F C CP GF A
Sbjct: 578 GYRFSEQQRKCVDIDECTQVQHLCSQG-RCENTEGSFLC-ICPAGF-----------MAS 624
Query: 372 SNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNP 431
C D+DEC CVNT+G++RC C GY Q C+ C NP P
Sbjct: 625 EEGTNCIDVDECLRPDVCGEGHCVNTVGAFRCEYCDSGYRMTQRGRCEDIDECLNPSTCP 684
Query: 432 CSVNAQCIEERQGDVTCV-CGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDNCKYV 490
+ QC+ G CV C G+ G G+ +D+D + + C+ +C Y+
Sbjct: 685 ---DEQCVNS-PGSYQCVPCTEGFRGWN---GQCLDVDECLEPNV-CANGDCSNLEGSYM 736
Score = 54.3 bits (129), Expect = 5e-07
Identities = 48/170 (28%), Positives = 65/170 (38%), Gaps = 32/170 (18%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDV------DECKYHPCYPGVHCINLSPGFRCDAC 353
+C G QCG G + C V ++C+ P P H N + C
Sbjct: 232 RCFQETIGSQCGKALPGLSKQEDCCGTVGTSWGFNKCQKCPKKPSYHGYN-----QMMEC 286
Query: 354 PVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGD 413
G+ + N C DI+EC+ PN C+NT+GSYRC CK G+ D
Sbjct: 287 LPGYK------------RVNNTFCQDINECQLQGVCPNGECLNTMGSYRC-TCKIGFGPD 333
Query: 414 -QIRGCKAERNCRNPELNPC----SVNAQCIEERQGDVT---CVCGVGWA 455
C + + E PC S QC+ +T C C VG A
Sbjct: 334 PTFSSCVPDPPVISEEKGPCYRLVSSGRQCMHPLSVHLTKQLCCCSVGKA 383
Score = 40.4 bits (93), Expect = 0.008
Identities = 26/81 (32%), Positives = 35/81 (43%), Gaps = 16/81 (19%)
Query: 326 DVDECKYHP---CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE 382
D DEC C G C+N PG+ C + P+ K C D+DE
Sbjct: 1099 DADECLLFGQEICKNGF-CLNTRPGYECYCKQGTYYDPV------------KLQCFDMDE 1145
Query: 383 CRNGACVPNSICVNTLGSYRC 403
C++ + + CVNT GSY C
Sbjct: 1146 CQDPSSCIDGQCVNTEGSYNC 1166
Score = 40.4 bits (93), Expect = 0.008
Identities = 28/96 (29%), Positives = 40/96 (41%), Gaps = 19/96 (19%)
Query: 320 NGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTD 379
N + +EC C+ + G+ CD C G+ + K C D
Sbjct: 1290 NSFEELQAEECGILNGCENGRCVRVQEGYTCD-CFDGY-----------HLDTAKMTCVD 1337
Query: 380 IDEC-----RNGACVPNSICVNTLGSYRCGPCKPGY 410
++EC R C N+ C+NT GSY+C C PGY
Sbjct: 1338 VNECDELNNRMSLC-KNAKCINTDGSYKC-LCLPGY 1371
Score = 34.3 bits (77), Expect = 0.57
Identities = 39/140 (27%), Positives = 58/140 (41%), Gaps = 18/140 (12%)
Query: 333 HPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR-NGACVPN 391
HP +PG+ SP + P T Q + + QV T+I+EC N
Sbjct: 509 HPQFPGIVIEKTSPPVPVEVAPEASTSSASQVI------APTQV-TEINECTVNPDICGA 561
Query: 392 SICVNTLGSYRCGPCKPGYT-GDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVC 450
C+N Y C C GY +Q R C C + + CS +C E +G C+C
Sbjct: 562 GHCINLPVRYTC-ICYEGYRFSEQQRKCVDIDECTQVQ-HLCS-QGRC-ENTEGSFLCIC 617
Query: 451 GVGW--AGDGYICGKDVDID 468
G+ + +G C +D+D
Sbjct: 618 PAGFMASEEGTNC---IDVD 634
>gi|61743978 stabilin 1 precursor [Homo sapiens]
Length = 2570
Score = 87.8 bits (216), Expect = 4e-17
Identities = 57/192 (29%), Positives = 80/192 (41%), Gaps = 24/192 (12%)
Query: 287 PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP--CYPGVHCINL 344
PR+CD N C G C GY+GNGI C +VD C + C P +C +
Sbjct: 1421 PRKCDPN-----ANCVQDSAGASTCACAAGYSGNGIFCSEVDPCAHGHGGCSPHANCTKV 1475
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGACVPNSICVNTLGSYR 402
+PG R C G+ G + ++C +I+ C +G C ++ C+ T
Sbjct: 1476 APGQRTCTCQDGYMG-------------DGELCQEINSCLIHHGGCHIHAECIPTGPQQV 1522
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVG-WAGDGYIC 461
C+ GY+GD IR C+ C CS A C G TC C GDG C
Sbjct: 1523 SCSCREGYSGDGIRTCELLDPCSKNN-GGCSPYATCKSTGDGQRTCTCDTAHTVGDGLTC 1581
Query: 462 GKDVDIDSYPDE 473
V ++ D+
Sbjct: 1582 RARVGLELLRDK 1593
Score = 67.4 bits (163), Expect = 6e-11
Identities = 63/243 (25%), Positives = 91/243 (37%), Gaps = 51/243 (20%)
Query: 292 SNPCFRGVQCTDSRDGF---QCGPCPEGYTGNGITCIDVDECKYHPCYPG-VHCINLSPG 347
S C + +Q D GF C PCP G G C +C+ G HC G
Sbjct: 1308 SYTCAKKIQVPDCCPGFFGTLCEPCPGGLGG---VCSGHGQCQDRFLGSGECHCHEGFHG 1364
Query: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCK 407
C+ C +G GP CT + +C +G C G C C
Sbjct: 1365 TACEVCELGRYGPN---------------CTGVCDCAHGLCQEG-----LQGDGSC-VCN 1403
Query: 408 PGYTGDQIRGCKAERNCRNPEL-NPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
G+ +G + ++ +P+ C NA C+++ G TC C G++G+G C +
Sbjct: 1404 VGW-----QGLRCDQKITSPQCPRKCDPNANCVQDSAGASTCACAAGYSGNGIFCS---E 1455
Query: 467 IDSYPDEELPCSAR-NCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVL 525
+D CS NC K GQ C + GDG L ++ N L
Sbjct: 1456 VDPCAHGHGGCSPHANCTK------VAPGQRTC-------TCQDGYMGDGELCQEINSCL 1502
Query: 526 IHN 528
IH+
Sbjct: 1503 IHH 1505
Score = 63.5 bits (153), Expect = 9e-10
Identities = 48/172 (27%), Positives = 66/172 (38%), Gaps = 8/172 (4%)
Query: 292 SNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYH--PCYPGVHCINLSPGFR 349
SNPC+ C+D G C Y GI C H C C++ R
Sbjct: 737 SNPCYGKGNCSDGIQGNGACLCFPDY--KGIACHICSNPNKHGEQCQEDCGCVHGLCDNR 794
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
+ V G G F + C ++ C ++ CV+ G RC C G
Sbjct: 795 PGSGGVCQQGTCAPGFSGRFCNESMGDCGPTGLAQH--CHLHARCVSQEGVARCR-CLDG 851
Query: 410 YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
+ GD C C +P+ CS NA+C+ G C C GW+GDG +C
Sbjct: 852 FEGDGF-SCTPSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVC 902
Score = 63.5 bits (153), Expect = 9e-10
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 41/199 (20%)
Query: 298 GVQCTDSRDGFQCGPCPEGYTGNGITCIDVD-------------ECKYHPCYPGVHCINL 344
G CT D G C EG G+G +V +C C P +C+
Sbjct: 1376 GPNCTGVCDCAH-GLCQEGLQGDGSCVCNVGWQGLRCDQKITSPQCP-RKCDPNANCVQD 1433
Query: 345 SPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYR 402
S G AC G++G N C+++D C +G C P++ C R
Sbjct: 1434 SAGASTCACAAGYSG-------------NGIFCSEVDPCAHGHGGCSPHANCTKVAPGQR 1480
Query: 403 CGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICG 462
C+ GY GD C+ +C C ++A+CI V+C C G++GDG
Sbjct: 1481 TCTCQDGYMGDG-ELCQEINSCLIHH-GGCHIHAECIPTGPQQVSCSCREGYSGDGIRTC 1538
Query: 463 KDVDIDSYPDEELPCSARN 481
+ +D PCS N
Sbjct: 1539 ELLD---------PCSKNN 1548
Score = 63.2 bits (152), Expect = 1e-09
Identities = 39/136 (28%), Positives = 54/136 (39%), Gaps = 18/136 (13%)
Query: 283 PTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYH---PCYPGV 339
P+ P D C +C G C +G++G+G C+ +DEC+ C+
Sbjct: 861 PSNPCSHPDRGGCSENAECVPGSLGTHHCTCHKGWSGDGRVCVAIDECELDMRGGCHTDA 920
Query: 340 HCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR--NGACVPNSICVNT 397
C + PG C +GF G Q C+ ID CR NG C + C
Sbjct: 921 LCSYVGPGQSRCTCKLGFAGDGYQ-------------CSPIDPCRAGNGGCHGLATCRAV 967
Query: 398 LGSYRCGPCKPGYTGD 413
G R C PG+ GD
Sbjct: 968 GGGQRVCTCPPGFGGD 983
Score = 62.0 bits (149), Expect = 3e-09
Identities = 51/179 (28%), Positives = 72/179 (40%), Gaps = 26/179 (14%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP----CYPGVHCINLSPGFRC 350
C +C S++G C +G+ G+G +C + C HP C C+ S G
Sbjct: 831 CHLHARCV-SQEGVARCRCLDGFEGDGFSCTPSNPCS-HPDRGGCSENAECVPGSLGTHH 888
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR---NGACVPNSICVNT-LGSYRCGPC 406
C G++G + +VC IDEC G C +++C G RC C
Sbjct: 889 CTCHKGWSG-------------DGRVCVAIDECELDMRGGCHTDALCSYVGPGQSRC-TC 934
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDV 465
K G+ GD + C CR C A C G C C G+ GDG+ C D+
Sbjct: 935 KLGFAGDGYQ-CSPIDPCRAGN-GGCHGLATCRAVGGGQRVCTCPPGFGGDGFSCYGDI 991
Score = 60.5 bits (145), Expect = 7e-09
Identities = 58/189 (30%), Positives = 77/189 (40%), Gaps = 33/189 (17%)
Query: 292 SNPCFRGVQCT----------DSRDGF----QCGPCPEGYTGNGITCIDVDECK----YH 333
SNP G QC D+R G Q G C G++G + +C
Sbjct: 771 SNPNKHGEQCQEDCGCVHGLCDNRPGSGGVCQQGTCAPGFSGRFCN-ESMGDCGPTGLAQ 829
Query: 334 PCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSI 393
C+ C++ RC C GF +G G S SN C+ D G C N+
Sbjct: 830 HCHLHARCVSQEGVARC-RCLDGF-----EGDGFSCTPSNP--CSHPDR---GGCSENAE 878
Query: 394 CV-NTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGV 452
CV +LG++ C C G++GD R C A C C +A C G C C +
Sbjct: 879 CVPGSLGTHHC-TCHKGWSGDG-RVCVAIDECELDMRGGCHTDALCSYVGPGQSRCTCKL 936
Query: 453 GWAGDGYIC 461
G+AGDGY C
Sbjct: 937 GFAGDGYQC 945
Score = 58.5 bits (140), Expect = 3e-08
Identities = 49/193 (25%), Positives = 78/193 (40%), Gaps = 24/193 (12%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C + C +C + G C EG+TG +++ PC P C G
Sbjct: 2018 CQACRCTVHGRCDEGLGGSGSCFCDEGWTGPRCEVQLELQPVCTPPCAPEAVC---RAGN 2074
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNG--ACVPNSICVNTLGSYRCGPC 406
C+ C +G+ G + +VCT D C++G C ++ C + +G+ C
Sbjct: 2075 SCE-CSLGYEG-------------DGRVCTVADLCQDGHGGCSEHANC-SQVGTMVTCTC 2119
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
P Y GD C+A C + CS +A C+ C C G+ GDG C ++ +
Sbjct: 2120 LPDYEGDGW-SCRARNPCTDGHRGGCSEHANCLSTGLNTRRCECHAGYVGDGLQCLEESE 2178
Query: 467 --IDSYPDEELPC 477
+D + PC
Sbjct: 2179 PPVDRCLGQPPPC 2191
Score = 51.2 bits (121), Expect = 5e-06
Identities = 48/190 (25%), Positives = 69/190 (36%), Gaps = 41/190 (21%)
Query: 335 CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSIC 394
C PG + G C ACP G + P S++ VC D +G C +C
Sbjct: 1959 CCPGHY------GSECQACPGGPSSPC----------SDRGVCMD-GMSGSGQC----LC 1997
Query: 395 VNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
+ C C PG G + C+ C+V+ +C E G +C C GW
Sbjct: 1998 RSGFAGTACELCAPGAFGPHCQACR------------CTVHGRCDEGLGGSGSCFCDEGW 2045
Query: 455 AGDGYICGKDVDIDSYPDEELPCSARN-CKKDNCKYVPNSGQEDADRDGIGDACDEDADG 513
G +V ++ P PC+ C+ N + D + D C DG
Sbjct: 2046 TGPRC----EVQLELQPVCTPPCAPEAVCRAGNSCECSLGYEGDGRVCTVADLCQ---DG 2098
Query: 514 DGILNEQDNC 523
G +E NC
Sbjct: 2099 HGGCSEHANC 2108
Score = 47.0 bits (110), Expect = 9e-05
Identities = 46/178 (25%), Positives = 60/178 (33%), Gaps = 27/178 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C C + QC+ +C P GYT G C + C PC C G
Sbjct: 199 CQELRCPQNTQCSAEAPSCRCLP---GYTQQGSECRAPNPCWPSPCSLLAQCSVSPKGQA 255
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNS-ICVNTLGSYRCGPC 406
CP + G + VC D C + G C NS +CV C
Sbjct: 256 QCHCPENYHG-------------DGMVCLPKDPCTDNLGGCPSNSTLCVYQKPGQAFCTC 302
Query: 407 KPG---YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYIC 461
+PG + GC A + + C +A C G +CVC GDG C
Sbjct: 303 RPGLVSINSNASAGCFAFCSPFS-----CDRSATCQVTADGKTSCVCRESEVGDGRAC 355
Score = 33.1 bits (74), Expect = 1.3
Identities = 36/163 (22%), Positives = 58/163 (35%), Gaps = 49/163 (30%)
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
G RC CP G P + C D + RNG CV C
Sbjct: 106 GSRCHECPGGAETPC----------NGHGTCLDGMD-RNGTCV----------------C 138
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCS-VNAQCIEERQGDVTCVCGVGWAGDGYICGKDV 465
+ + G + C+ + CS V+ C +GD +C+C G+ G
Sbjct: 139 QENFRGSACQECQDPNRFGPDCQSVCSCVHGVCNHGPRGDGSCLCFAGYTG--------- 189
Query: 466 DIDSYPDEELP-CSARNCKKD--------NCKYVPNSGQEDAD 499
+ D+ELP C C ++ +C+ +P Q+ ++
Sbjct: 190 ---PHCDQELPVCQELRCPQNTQCSAEAPSCRCLPGYTQQGSE 229
Score = 32.3 bits (72), Expect = 2.2
Identities = 23/87 (26%), Positives = 35/87 (40%), Gaps = 12/87 (13%)
Query: 406 CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDV 465
C PGY G + C PC+ + C++ + TCVC + G C +
Sbjct: 100 CCPGYWGSRCHECPGGAE------TPCNGHGTCLDGMDRNGTCVCQENFRGSA--CQECQ 151
Query: 466 DIDSY-PDEELPCSARNCKKDNCKYVP 491
D + + PD + CS C C + P
Sbjct: 152 DPNRFGPDCQSVCS---CVHGVCNHGP 175
>gi|24041035 notch 2 preproprotein [Homo sapiens]
Length = 2471
Score = 87.0 bits (214), Expect = 7e-17
Identities = 94/339 (27%), Positives = 135/339 (39%), Gaps = 65/339 (19%)
Query: 290 CDSNPCFRGVQC-TDSRDGFQCGPCPEGYTGNGITCIDVDECKY---HPCYPGVHCINLS 345
C SNPC +G C T+ +G CP+GY G T DVDEC +PC C+N
Sbjct: 379 CISNPCHKGALCDTNPLNGQYICTCPQGYKGADCT-EDVDECAMANSNPCEHAGKCVNTD 437
Query: 346 PGFRCDACPVGFTGPMVQGVGISFAKS----NKQVCTD---------------------I 380
F C+ C G+ GP + + I+ S N C D I
Sbjct: 438 GAFHCE-CLKGYAGPRCE-MDINECHSDPCQNDATCLDKIGGFTCLCMPGFKGVHCELEI 495
Query: 381 DECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAE-RNCRNPELNPCSVNAQCI 439
+EC++ CV N CV+ + ++C C PG+TG C+ + +C + PC A+CI
Sbjct: 496 NECQSNPCVNNGQCVDKVNRFQC-LCPPGFTGPV---CQIDIDDCSS---TPCLNGAKCI 548
Query: 440 EERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKK--DNCKYVPNSGQED 497
+ G C C G+ G +C +++D + PD PC C+ D+ + N G
Sbjct: 549 DHPNG-YECQCATGFT--GVLCEENID-NCDPD---PCHHGQCQDGIDSYTCICNPGY-- 599
Query: 498 ADRDGIGDACDEDAD---GDGILNEQDNCVLIHNVDQRNSDKDIFGDAC----DNCLSVL 550
+G C + D LN+ C+ + N Q N G C D+C S
Sbjct: 600 -----MGAICSDQIDECYSSPCLND-GRCIDLVNGYQCNCQPGTSGVNCEINFDDCASNP 653
Query: 551 NNDQKDTDGDGR-GDACDDDMDGDGIKNILDNCPKFPNR 588
DG R C G +D C P R
Sbjct: 654 CIHGICMDGINRYSCVCSPGFTGQRCNIDIDECASNPCR 692
Score = 85.1 bits (209), Expect = 3e-16
Identities = 55/168 (32%), Positives = 83/168 (49%), Gaps = 26/168 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINLSPGF 348
C S PC G C+D + + C C G+ +G+ C + ++EC C+ G C++ F
Sbjct: 953 CLSEPCKNGGTCSDYVNSYTC-KCQAGF--DGVHCENNINECTESSCFNGGTCVDGINSF 1009
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C CPVGFTG SF +I+EC + C+ CV+ LG+YRC C
Sbjct: 1010 SC-LCPVGFTG--------SFCLH------EINECSSHPCLNEGTCVDGLGTYRCS-CPL 1053
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
GYTG + C+ N + +PC C+ +++ + C+C GWAG
Sbjct: 1054 GYTG---KNCQTLVNLCS--RSPCKNKGTCV-QKKAESQCLCPSGWAG 1095
Score = 85.1 bits (209), Expect = 3e-16
Identities = 58/171 (33%), Positives = 82/171 (47%), Gaps = 29/171 (16%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C SNPC G C+D G++C C GY G+ C +VDEC+ PC G CI+L F
Sbjct: 1153 CASNPCQHGATCSDFIGGYRC-ECVPGY--QGVNCEYEVDECQNQPCQNGGTCIDLVNHF 1209
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTLGSYRCGPCK 407
+C +CP G G + + +ID+C G C+ C++ +G Y C C
Sbjct: 1210 KC-SCPPGTRGLLCE--------------ENIDDCARGPHCLNGGQCMDRIGGYSC-RCL 1253
Query: 408 PGYTGDQIRGCKAERNCRNPELNPCSV--NAQCIEERQGDVTCVCGVGWAG 456
PG+ G++ G E C + NPCS + CI + D CVC + G
Sbjct: 1254 PGFAGERCEGDINE--CLS---NPCSSEGSLDCI-QLTNDYLCVCRSAFTG 1298
Score = 84.0 bits (206), Expect = 6e-16
Identities = 67/227 (29%), Positives = 88/227 (38%), Gaps = 46/227 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C SNPC G+ C D + + C C G+TG ID+DEC +PC G CIN GFR
Sbjct: 649 CASNPCIHGI-CMDGINRYSC-VCSPGFTGQRCN-IDIDECASNPCRKGATCINGVNGFR 705
Query: 350 CDACPVG-------------FTGPMVQGVGISFAKSNKQVC----------TDIDECRNG 386
C CP G + P + G K +C D +EC +
Sbjct: 706 C-ICPEGPHHPSCYSQVNECLSNPCIHGNCTGGLSGYKCLCDAGWVGINCEVDKNECLSN 764
Query: 387 ACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDV 446
C C N + YRC CK G+ +G + N NPC C ++ G
Sbjct: 765 PCQNGGTCDNLVNGYRC-TCKKGF-----KGYNCQVNIDECASNPCLNQGTCFDDISG-Y 817
Query: 447 TCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKKDN-CKYVPN 492
TC C + + G C + PCS C+ CK PN
Sbjct: 818 TCHCVLPYTGKN--CQTVL---------APCSPNPCENAAVCKESPN 853
Score = 80.1 bits (196), Expect = 9e-15
Identities = 61/203 (30%), Positives = 85/203 (41%), Gaps = 36/203 (17%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP-CYPGVHCINLSPGF 348
C S+PC G CT + F C C G+TG DV+EC C G C+NL +
Sbjct: 148 CLSHPCANGSTCTTVANQFSC-KCLTGFTGQKCET-DVNECDIPGHCQHGGTCLNLPGSY 205
Query: 349 RCDACPVGFTGPMVQGVGISFAKS---NKQVCT----------------------DIDEC 383
+C CP GFTG + + A S N C +ID+C
Sbjct: 206 QCQ-CPQGFTGQYCDSLYVPCAPSPCVNGGTCRQTGDFTFECNCLPGFEGSTCERNIDDC 264
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQ 443
N C +CV+ + +Y C C P +TG + C + + + N C C R
Sbjct: 265 PNHRCQNGGVCVDGVNTYNC-RCPPQWTG---QFCTEDVDECLLQPNACQNGGTC-ANRN 319
Query: 444 GDVTCVCGVGWAGDGYICGKDVD 466
G CVC GW+GD C +++D
Sbjct: 320 GGYGCVCVNGWSGDD--CSENID 340
Score = 77.4 bits (189), Expect = 6e-14
Identities = 55/194 (28%), Positives = 84/194 (43%), Gaps = 36/194 (18%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C SNPC G C + +G++C C +G+ G +++DEC +PC C + G+
Sbjct: 761 CLSNPCQNGGTCDNLVNGYRC-TCKKGFKGYNCQ-VNIDECASNPCLNQGTCFDDISGYT 818
Query: 350 CDACPVGFTGPMVQGVGISFAKS---NKQVCT-----------------------DIDEC 383
C C + +TG Q V + + N VC DIDEC
Sbjct: 819 CH-CVLPYTGKNCQTVLAPCSPNPCENAAVCKESPNFESYTCLCAPGWQGQRCTIDIDEC 877
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQ 443
+ C+ + +C NT GSY C C PG++ G E + + NPC C+ +
Sbjct: 878 ISKPCMNHGLCHNTQGSYMC-ECPPGFS-----GMDCEEDIDDCLANPCQNGGSCM-DGV 930
Query: 444 GDVTCVCGVGWAGD 457
+C+C G+ GD
Sbjct: 931 NTFSCLCLPGFTGD 944
Score = 74.7 bits (182), Expect = 4e-13
Identities = 90/346 (26%), Positives = 119/346 (34%), Gaps = 73/346 (21%)
Query: 292 SNPCFRGVQCTD-SRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRC 350
S PC G C SRD ++C C G+TG C D C HPC G C ++ F C
Sbjct: 112 SRPCLNGGTCHMLSRDTYEC-TCQVGFTGK--ECQWTDACLSHPCANGSTCTTVANQFSC 168
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECR-NGACVPNSICVNTLGSYRCGPCKPG 409
C GFTG + TD++EC G C C+N GSY+C C G
Sbjct: 169 -KCLTGFTGQKCE--------------TDVNECDIPGHCQHGGTCLNLPGSYQC-QCPQG 212
Query: 410 YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDS 469
+TG C + P +PC C + GD T C +G C +++D
Sbjct: 213 FTGQY---CDSLYVPCAP--SPCVNGGTC--RQTGDFTFECNCLPGFEGSTCERNID--- 262
Query: 470 YPDEELPCSARNCKKDN-CKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIHN 528
C C+ C N+ G C ED D C+L N
Sbjct: 263 ------DCPNHRCQNGGVCVDGVNTYNCRCPPQWTGQFCTEDV---------DECLLQPN 307
Query: 529 VDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPKFPNR 588
Q G C N G G C + GD +D+C F +
Sbjct: 308 ACQN-------GGTCAN------------RNGGYGCVCVNGWSGDDCSENIDDC-AFASC 347
Query: 589 DQRDKDGDGVGDACDSCPDVSNPNQSDVDNDLV------GDSCDTN 628
D V CP+ +D+ + G CDTN
Sbjct: 348 TPGSTCIDRVASFSCMCPEGKAGLLCHLDDACISNPCHKGALCDTN 393
Score = 70.5 bits (171), Expect = 7e-12
Identities = 48/164 (29%), Positives = 74/164 (45%), Gaps = 25/164 (15%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINLSPGFRCDAC 353
C C ++ + C CP GYTG+ C + +DEC +PC G C + G+RC+
Sbjct: 1120 CQHSGVCINAGNTHYC-QCPLGYTGS--YCEEQLDECASNPCQHGATCSDFIGGYRCECV 1176
Query: 354 PVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGD 413
P G+ QGV + ++DEC+N C C++ + ++C C PG
Sbjct: 1177 P-GY-----QGVNCEY---------EVDECQNQPCQNGGTCIDLVNHFKCS-CPPG---- 1216
Query: 414 QIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGD 457
RG E N + P +N +R G +C C G+AG+
Sbjct: 1217 -TRGLLCEENIDDCARGPHCLNGGQCMDRIGGYSCRCLPGFAGE 1259
Score = 69.3 bits (168), Expect = 2e-11
Identities = 54/180 (30%), Positives = 74/180 (41%), Gaps = 29/180 (16%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP--CYPGVHCINLSPG 347
C ++ C G C D + + C CP +TG T DVDEC P C G C N + G
Sbjct: 264 CPNHRCQNGGVCVDGVNTYNCR-CPPQWTGQFCT-EDVDECLLQPNACQNGGTCANRNGG 321
Query: 348 FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCK 407
+ C C G++G +ID+C +C P S C++ + S+ C C
Sbjct: 322 YGC-VCVNGWSGD--------------DCSENIDDCAFASCTPGSTCIDRVASFSC-MCP 365
Query: 408 PGYTGDQIRGCKAERNCRNPELNPCSVNAQC-IEERQGDVTCVCGVGWAGDGYICGKDVD 466
G G C + C + NPC A C G C C G+ G C +DVD
Sbjct: 366 EGKAG---LLCHLDDACIS---NPCHKGALCDTNPLNGQYICTCPQGYKGAD--CTEDVD 417
Score = 68.2 bits (165), Expect = 4e-11
Identities = 47/168 (27%), Positives = 72/168 (42%), Gaps = 26/168 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDECKYHPCYPGVHCINLSPGF 348
C S PC C +++ + C CP G++G + C D+D+C +PC G C++ F
Sbjct: 877 CISKPCMNHGLCHNTQGSYMC-ECPPGFSG--MDCEEDIDDCLANPCQNGGSCMDGVNTF 933
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C C GFTG Q TD++EC + C C + + SY C C+
Sbjct: 934 SC-LCLPGFTGDKCQ--------------TDMNECLSEPCKNGGTCSDYVNSYTC-KCQA 977
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
G+ G E N + C C+ + +C+C VG+ G
Sbjct: 978 GFD-----GVHCENNINECTESSCFNGGTCV-DGINSFSCLCPVGFTG 1019
Score = 41.6 bits (96), Expect = 0.004
Identities = 33/133 (24%), Positives = 44/133 (33%), Gaps = 33/133 (24%)
Query: 332 YHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPN 391
Y PC C+ G CP GF G + C D C C
Sbjct: 32 YEPCVNEGMCVTYHNGTGYCKCPEGFLG---------------EYCQHRDPCEKNRCQNG 76
Query: 392 SICV--NTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEE------RQ 443
CV LG C C G+TG+ +C+ +PC V+ C+ +
Sbjct: 77 GTCVAQAMLGKATC-RCASGFTGE---------DCQYSTSHPCFVSRPCLNGGTCHMLSR 126
Query: 444 GDVTCVCGVGWAG 456
C C VG+ G
Sbjct: 127 DTYECTCQVGFTG 139
>gi|110735443 delta-like 1 [Homo sapiens]
Length = 723
Score = 85.5 bits (210), Expect = 2e-16
Identities = 56/173 (32%), Positives = 72/173 (41%), Gaps = 35/173 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C PCF G +C+DS DG CP GY +G C +D C PC G C++L +
Sbjct: 370 CADGPCFNGGRCSDSPDGGYSCRCPVGY--SGFNCEKKIDYCSSSPCSNGAKCVDLGDAY 427
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTD-IDECRNGACVPNSICVNTLGSYRCGPCK 407
C C GF+G + C D +D+C + C C + + + C C
Sbjct: 428 LC-RCQAGFSG---------------RHCDDNVDDCASSPCANGGTCRDGVNDFSC-TCP 470
Query: 408 PGYTGDQIRGCKAERNCRNP----ELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
PGYTG RNC P E PC A C ER C C G+ G
Sbjct: 471 PGYTG---------RNCSAPVSRCEHAPCHNGATC-HERGHRYVCECARGYGG 513
Score = 68.9 bits (167), Expect = 2e-11
Identities = 61/224 (27%), Positives = 89/224 (39%), Gaps = 43/224 (19%)
Query: 294 PCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGFRCDA 352
PC G CT++ G C GYT G TC + +DEC PC G C +L + C
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYT--GATCELGIDECDPSPCKNGGSCTDLENSYSC-T 353
Query: 353 CPVGFTGPMVQGVGISFAKS---NKQVCTD----------------------IDECRNGA 387
CP GF G + + ++ A N C+D ID C +
Sbjct: 354 CPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKKIDYCSSSP 413
Query: 388 CVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVT 447
C + CV+ +Y C C+ G++G R C + N + +PC+ C + D +
Sbjct: 414 CSNGAKCVDLGDAYLC-RCQAGFSG---RHC--DDNVDDCASSPCANGGTC-RDGVNDFS 466
Query: 448 CVCGVGWAGDGYICGKDVDIDSYPDEELPC-SARNCKKDNCKYV 490
C C G+ G C V E PC + C + +YV
Sbjct: 467 CTCPPGYTGRN--CSAPVS----RCEHAPCHNGATCHERGHRYV 504
Score = 64.7 bits (156), Expect = 4e-10
Identities = 55/194 (28%), Positives = 79/194 (40%), Gaps = 33/194 (17%)
Query: 288 RRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDECKYH-PCYPGVHCINLS 345
R CD + G + +QC C EG+ G+ C D++ C +H PC G C N
Sbjct: 252 RYCDECIRYPGCLHGTCQQPWQCN-CQEGW--GGLFCNQDLNYCTHHKPCKNGATCTNTG 308
Query: 346 PGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGP 405
G +C G+TG + IDEC C C + SY C
Sbjct: 309 QGSYTCSCRPGYTGATCE--------------LGIDECDPSPCKNGGSCTDLENSYSC-T 353
Query: 406 CKPGYTGDQIRGCK-AERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKD 464
C PG+ G + C+ + C + PC +C + G +C C VG++ G+ C K
Sbjct: 354 CPPGFYG---KICELSAMTCAD---GPCFNGGRCSDSPDGGYSCRCPVGYS--GFNCEKK 405
Query: 465 VDIDSYPDEELPCS 478
+D S PCS
Sbjct: 406 IDYCS----SSPCS 415
Score = 30.8 bits (68), Expect = 6.4
Identities = 47/190 (24%), Positives = 62/190 (32%), Gaps = 30/190 (15%)
Query: 431 PCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCKK-DNCKY 489
PC A C QG TC C G+ G G D C CK +C
Sbjct: 297 PCKNGATCTNTGQGSYTCSCRPGYTGATCELGID-----------ECDPSPCKNGGSCTD 345
Query: 490 VPNSGQEDADRDGIGDACDEDA---------DGDGILNEQD---NCVLIHNVDQRNSDKD 537
+ NS G C+ A +G + D +C N +K
Sbjct: 346 LENSYSCTCPPGFYGKICELSAMTCADGPCFNGGRCSDSPDGGYSCRCPVGYSGFNCEKK 405
Query: 538 IFGDACDNCLSVLNNDQKDTD-GDGRGDACDDDMDGDGIKNILDNCPKFPNRDQRDKDGD 596
I D C + S +N K D GD C G + +D+C P + D
Sbjct: 406 I--DYCSS--SPCSNGAKCVDLGDAYLCRCQAGFSGRHCDDNVDDCASSPCAN-GGTCRD 460
Query: 597 GVGDACDSCP 606
GV D +CP
Sbjct: 461 GVNDFSCTCP 470
>gi|21704279 jagged 2 isoform b precursor [Homo sapiens]
Length = 1200
Score = 85.5 bits (210), Expect = 2e-16
Identities = 59/180 (32%), Positives = 85/180 (47%), Gaps = 31/180 (17%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C SNPC G C + GF+C CP G++G TC +D+DEC +PC G C++ GF
Sbjct: 351 CTSNPCANGGSCHEVPSGFECH-CPSGWSGP--TCALDIDECASNPCAAGGTCVDQVDGF 407
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C CP + G Q D+++CR G C C + + Y+C C
Sbjct: 408 EC-ICPEQWVGATCQ--------------LDVNDCR-GQCQHGGTCKDLVNGYQC-VCPR 450
Query: 409 GYTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDI 467
G+ G R C+ ER+ C + +PC C E+ C C G++G +C DVD+
Sbjct: 451 GFGG---RHCELERDECAS---SPCHSGGLC-EDLADGFHCHCPQGFSGP--LCEVDVDL 501
Score = 84.3 bits (207), Expect = 5e-16
Identities = 62/231 (26%), Positives = 87/231 (37%), Gaps = 73/231 (31%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTG------------------------NGITCI 325
C SNPC G C D DGF+C CPE + G NG C+
Sbjct: 389 CASNPCAAGGTCVDQVDGFEC-ICPEQWVGATCQLDVNDCRGQCQHGGTCKDLVNGYQCV 447
Query: 326 ------------DVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN 373
+ DEC PC+ G C +L+ GF C CP GF+GP+ +
Sbjct: 448 CPRGFGGRHCELERDECASSPCHSGGLCEDLADGFHCH-CPQGFSGPLCE---------- 496
Query: 374 KQVCTDIDECRNGACVPNSICVNTLGSYRCG---------------PCKPGYTGDQIRGC 418
D+D C C + C N G Y C PC PG I GC
Sbjct: 497 ----VDVDLCEPSPCRNGARCYNLEGDYYCACPDDFGGKNCSVPREPC-PGGACRVIDGC 551
Query: 419 KAERNCRNP---ELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
++ P C + +C+ + G+ +C+C G+ G C +++D
Sbjct: 552 GSDAGPGMPGTAASGVCGPHGRCVSQPGGNFSCICDSGFTGT--YCHENID 600
Score = 75.5 bits (184), Expect = 2e-13
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 25/169 (14%)
Query: 289 RCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGF 348
+CD+ C G C DS D F+C CP G+ G+ C +PC G C+ F
Sbjct: 677 QCDAYTCSNGGTCYDSGDTFRCA-CPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASF 735
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCT-DIDECRNGACVPNSICVNTLGSYRCGPCK 407
C C G+ G + CT + ++C C ICV+ + +RC C
Sbjct: 736 SC-ICRDGWEG---------------RTCTHNTNDCNPLPCYNGGICVDGVNWFRC-ECA 778
Query: 408 PGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
PG+ G R N + +PC+ A C++E G C C G AG
Sbjct: 779 PGFAGPDCR-----INIDECQSSPCAYGATCVDEING-YRCSCPPGRAG 821
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C+ PC+ G C D + F+C C G+ G I++DEC+ PC G C++ G+R
Sbjct: 755 CNPLPCYNGGICVDGVNWFRC-ECAPGFAGPDCR-INIDECQSSPCAYGATCVDEINGYR 812
Query: 350 CDACPVGFTGPMVQGVGISFAKS 372
C +CP G GP Q V I F +S
Sbjct: 813 C-SCPPGRAGPRCQEV-IGFGRS 833
Score = 49.7 bits (117), Expect = 1e-05
Identities = 50/196 (25%), Positives = 70/196 (35%), Gaps = 36/196 (18%)
Query: 287 PRRCDSNPCFRGVQCTDSRDG-FQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINL 344
P S C +C G F C C G+TG C + +D+C PC G CI+
Sbjct: 560 PGTAASGVCGPHGRCVSQPGGNFSC-ICDSGFTGT--YCHENIDDCLGQPCRNGGTCIDE 616
Query: 345 SPGFRCDACPVGFTGPM------------VQGVGISFAKSNKQVCTDID----------- 381
FRC CP G+ G + G + N C D
Sbjct: 617 VDAFRC-FCPSGWEGELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSRE 675
Query: 382 -ECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIE 440
+C C C ++ ++RC C PG+ G C +N + NPC C+
Sbjct: 676 FQCDAYTCSNGGTCYDSGDTFRCA-CPPGWKGST---CAVAKN-SSCLPNPCVNGGTCVG 730
Query: 441 ERQGDVTCVCGVGWAG 456
+C+C GW G
Sbjct: 731 S-GASFSCICRDGWEG 745
Score = 49.3 bits (116), Expect = 2e-05
Identities = 58/229 (25%), Positives = 87/229 (37%), Gaps = 41/229 (17%)
Query: 288 RRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDEC-KYHPCYPGVHCINLS 345
R CD + G + +QC C + G+ C D++ C +HPC G CIN
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCN-CETNW--GGLLCDKDLNYCGSHHPCTNGGTCINAE 327
Query: 346 PG-FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCG 404
P +RC CP G++G + + CT + C NG C + C
Sbjct: 328 PDQYRC-TCPDGYSG--------RNCEKAEHACTS-NPCANGGS-----CHEVPSGFEC- 371
Query: 405 PCKPGYTGDQIRGCKAE-RNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGK 463
C G++G C + C + NPC+ C+++ G C+C W G C
Sbjct: 372 HCPSGWSGPT---CALDIDECAS---NPCAAGGTCVDQVDG-FECICPEQWV--GATCQL 422
Query: 464 DVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDAD 512
DV+ C + CK + N Q R G C+ + D
Sbjct: 423 DVN---------DCRGQCQHGGTCKDLVNGYQCVCPRGFGGRHCELERD 462
>gi|148833508 notch1 preproprotein [Homo sapiens]
Length = 2555
Score = 85.1 bits (209), Expect = 3e-16
Identities = 81/296 (27%), Positives = 107/296 (36%), Gaps = 56/296 (18%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S+PC +C D + FQC CP G+TG+ + DVDEC PC G C++ +
Sbjct: 494 CASSPCLHNGRCLDKINEFQC-ECPTGFTGH-LCQYDVDECASTPCKNGAKCLDGPNTYT 551
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C C G+TG + DIDEC C S C + + ++ C C+PG
Sbjct: 552 C-VCTEGYTGTHCE--------------VDIDECDPDPCHYGS-CKDGVATFTC-LCRPG 594
Query: 410 YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGD----------GY 459
YTG E N PC C ++R C C G G
Sbjct: 595 YTGHH-----CETNINECSSQPCRHGGTC-QDRDNAYLCFCLKGTTGPNCEINLDDCASS 648
Query: 460 ICGKDVDIDSYPDEELPC------SARNCKKDNCKYVP--NSGQEDADRDGIGDACDEDA 511
C +D E C S N D C P N G + +G C E
Sbjct: 649 PCDSGTCLDKIDGYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGY 708
Query: 512 DGDGILNEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACD 567
L+E + C NS+ + G C LN + D D G CD
Sbjct: 709 HDPTCLSEVNEC---------NSNPCVHG----ACRDSLNGYKCDCDPGWSGTNCD 751
Score = 85.1 bits (209), Expect = 3e-16
Identities = 97/400 (24%), Positives = 141/400 (35%), Gaps = 68/400 (17%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINLSPGF 348
C S+PC G CTD D + C CP G++G I C + +C C+ G C++ F
Sbjct: 949 CASDPCRNGANCTDCVDSYTC-TCPAGFSG--IHCENNTPDCTESSCFNGGTCVDGINSF 1005
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C CP GFTG Q D++EC + C+ C + GSYRC C
Sbjct: 1006 TC-LCPPGFTGSYCQH--------------DVNECDSQPCLHGGTCQDGCGSYRC-TCPQ 1049
Query: 409 GYTGDQIRGCKAERNCRN----PELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKD 464
GYTG NC+N + +PC +C + C C GW G Y
Sbjct: 1050 GYTGP---------NCQNLVHWCDSSPCKNGGKCWQTHT-QYRCECPSGWTG-LYCDVPS 1098
Query: 465 VDIDSYPDEELPCSARNCKKDN-CKYVPNSGQEDADRDGIGDACDEDAD----------- 512
V + + AR C+ C N+ G C++ D
Sbjct: 1099 VSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGSYCEDLVDECSPSPCQNGA 1158
Query: 513 --GDGILNEQDNCVL-IHNVDQRNSDKDIFGDACDN---CLSVLNNDQKDTDGDGRGDAC 566
D + CV H V+ + C N CL + N + +G C
Sbjct: 1159 TCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLDLPNTYKCSCPRGTQGVHC 1218
Query: 567 DDDMDGDGIKNILDNCPKFPNRDQRDKDGDGVGDACDSCPD--VSNPNQSDVDNDLVGDS 624
+++ D +D + P D VG +CP V + DV N+ + +
Sbjct: 1219 --EINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGERCEGDV-NECLSNP 1275
Query: 625 CDTNQDSDGDGHQDSTDNCPTVINSAQLDTDKDGIGDECD 664
CD T NC +N + G C+
Sbjct: 1276 CDAR----------GTQNCVQRVNDFHCECRAGHTGRRCE 1305
Score = 84.0 bits (206), Expect = 6e-16
Identities = 85/348 (24%), Positives = 142/348 (40%), Gaps = 55/348 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C SNPC C D FQC C GY G+ C ++ DEC PC C++ F
Sbjct: 456 CVSNPCQNDATCLDQIGEFQC-ICMPGY--EGVHCEVNTDECASSPCLHNGRCLDKINEF 512
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
+C+ CP GFTG + Q D+DEC + C + C++ +Y C C
Sbjct: 513 QCE-CPTGFTGHLCQ--------------YDVDECASTPCKNGAKCLDGPNTYTC-VCTE 556
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDID 468
GYTG C+ + + +P+ PC + ++ TC+C G+ G+ C +++
Sbjct: 557 GYTGTH---CEVDIDECDPD--PCHYGS--CKDGVATFTCLCRPGYT--GHHCETNIN-- 605
Query: 469 SYPDEELPCSARNCKK-DNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQDNCVLIH 527
CS++ C+ C+ N+ + G C+ + D D + D+ +
Sbjct: 606 -------ECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLD-DCASSPCDSGTCLD 657
Query: 528 NVD--QRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKNILDNCPK- 584
+D + + G C+ +N D+ + G C+ DGI CP+
Sbjct: 658 KIDGYECACEPGYTGSMCN-----INIDECAGNPCHNGGTCE-----DGINGFTCRCPEG 707
Query: 585 FPNRDQRDKDGDGVGDAC--DSCPDVSNPNQSDVDNDLVGDSCDTNQD 630
+ + + + + C +C D N + D D G +CD N +
Sbjct: 708 YHDPTCLSEVNECNSNPCVHGACRDSLNGYKCDCDPGWSGTNCDINNN 755
Score = 83.6 bits (205), Expect = 8e-16
Identities = 54/167 (32%), Positives = 80/167 (47%), Gaps = 26/167 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S+PC G C D DG++C C GYTG+ + I++DEC +PC+ G C + GF
Sbjct: 645 CASSPCDSGT-CLDKIDGYECA-CEPGYTGS-MCNINIDECAGNPCHNGGTCEDGINGFT 701
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C CP G+ P ++++EC + CV + C ++L Y+C C PG
Sbjct: 702 C-RCPEGYHDP--------------TCLSEVNECNSNPCV-HGACRDSLNGYKC-DCDPG 744
Query: 410 YTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
++ G + N E NPC C + G V C C G++G
Sbjct: 745 WS-----GTNCDINNNECESNPCVNGGTCKDMTSGYV-CTCREGFSG 785
Score = 80.9 bits (198), Expect = 5e-15
Identities = 84/304 (27%), Positives = 122/304 (40%), Gaps = 67/304 (22%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDECKYHPCYPGVHCINLSPGF 348
C NPC G C D +GF C CPEGY + TC+ +V+EC +PC G C + G+
Sbjct: 682 CAGNPCHNGGTCEDGINGFTC-RCPEGY--HDPTCLSEVNECNSNPCVHGA-CRDSLNGY 737
Query: 349 RCDACPVGFTG-------------PMVQGVGISFAKSNKQVC------------TDIDEC 383
+CD C G++G P V G G ++ VC T+I+EC
Sbjct: 738 KCD-CDPGWSGTNCDINNNECESNPCVNG-GTCKDMTSGYVCTCREGFSGPNCQTNINEC 795
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIE-ER 442
+ C+ C++ + Y+C C YTG C+ P +PC +C + E
Sbjct: 796 ASNPCLNQGTCIDDVAGYKCN-CLLPYTG---ATCEVVLAPCAP--SPCRNGGECRQSED 849
Query: 443 QGDVTCVCGVGWAGDGYICGKDVD-------------IDSYPDEELPC----SARNCKKD 485
+CVC GW G C D++ +++ C S RNC+ D
Sbjct: 850 YESFSCVCPTGW--QGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYSGRNCETD 907
Query: 486 NCKYVPNSGQEDAD-RDGIGDA-CDEDADGDGILNEQDNCVLIHNVDQRNSDKDIFGDAC 543
PN DGI A CD G E+D +++ SD G C
Sbjct: 908 IDDCRPNPCHNGGSCTDGINTAFCDCLPGFRGTFCEED-------INECASDPCRNGANC 960
Query: 544 DNCL 547
+C+
Sbjct: 961 TDCV 964
Score = 80.1 bits (196), Expect = 9e-15
Identities = 53/170 (31%), Positives = 73/170 (42%), Gaps = 28/170 (16%)
Query: 290 CDSNPCFRGVQCTDSRD--GFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSP 346
C +PC G +C S D F C CP G+ G TC +D++EC PC G C N
Sbjct: 833 CAPSPCRNGGECRQSEDYESFSC-VCPTGWQGQ--TCEVDINECVLSPCRHGASCQNTHG 889
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPC 406
G+RC C G++G + TDID+CR C C + + + C C
Sbjct: 890 GYRCH-CQAGYSG--------------RNCETDIDDCRPNPCHNGGSCTDGINTAFC-DC 933
Query: 407 KPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
PG+ RG E + +PC A C + TC C G++G
Sbjct: 934 LPGF-----RGTFCEEDINECASDPCRNGANC-TDCVDSYTCTCPAGFSG 977
Score = 77.4 bits (189), Expect = 6e-14
Identities = 93/360 (25%), Positives = 132/360 (36%), Gaps = 96/360 (26%)
Query: 290 CDSNPCFRGVQCTD-SRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGF 348
C +NPC G C + ++C CP G++G +C D C +PC G C+ +
Sbjct: 106 CLTNPCRNGGTCDLLTLTEYKCR-CPPGWSGK--SCQQADPCASNPCANGGQCLPFEASY 162
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC--RNGACVPNSICVNTLGSYRCGPC 406
C CP F GP + D++EC + G C C N +GSYRC C
Sbjct: 163 ICH-CPPSFHGPTCR--------------QDVNECGQKPGLCRHGGTCHNEVGSYRC-VC 206
Query: 407 KPGYTGDQIRGCKAERNCRNPEL----NPCSVNAQCIEERQGDVT--CVCGVGWAGDGYI 460
+ +TG NC P + +PC C GDVT C C G+ G
Sbjct: 207 RATHTGP---------NCERPYVPCSPSPCQNGGTC--RPTGDVTHECACLPGFTGQN-- 253
Query: 461 CGKDVDIDSYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGD---ACDEDADGDGIL 517
C +++D +C +NCK N G A DG+ C + G
Sbjct: 254 CEENID--------------DCPGNNCK---NGG---ACVDGVNTYNCRCPPEWTGQYCT 293
Query: 518 NEQDNCVLIHNVDQRNSDKDIFGDACDNCLSVLNNDQKDTDGDGRGDACDDDMDGDGIKN 577
+ D C L+ N Q G C N T G G C + G+
Sbjct: 294 EDVDECQLMPNACQN-------GGTCHN-----------THG-GYNCVCVNGWTGEDCSE 334
Query: 578 ILDNCPK---FPNRDQRDKDGDGVGDACDSCPD-----VSNPNQSDVDNDL-VGDSCDTN 628
+D+C F D+ V CP + + N + + N G +CDTN
Sbjct: 335 NIDDCASAACFHGATCHDR----VASFYCECPHGRTGLLCHLNDACISNPCNEGSNCDTN 390
Score = 67.4 bits (163), Expect = 6e-11
Identities = 62/225 (27%), Positives = 90/225 (40%), Gaps = 36/225 (16%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGNGITCID-VDECKYHPCYPGVHCINLSPGFRCDAC 353
C G C D+ + C C GYTG+ C D VDEC PC G C + G+ C C
Sbjct: 1116 CQHGGLCVDAGNTHHCR-CQAGYTGS--YCEDLVDECSPSPCQNGATCTDYLGGYSC-KC 1171
Query: 354 PVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGD 413
G+ GV S +IDEC + C C++ +Y+C C G G
Sbjct: 1172 VAGY-----HGVNCS---------EEIDECLSHPCQNGGTCLDLPNTYKCS-CPRGTQGV 1216
Query: 414 QIRGCKAERNCRNPELNPCSVNAQCIE-----ERQGDVTCVCGVGWAGDGYICGKDVDID 468
C+ + NP ++P S + +C ++ G +C C G+ G+ C DV+
Sbjct: 1217 H---CEINVDDCNPPVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFVGER--CEGDVN-- 1269
Query: 469 SYPDEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADG 513
PC AR + NC N + G C+ +G
Sbjct: 1270 --ECLSNPCDARGTQ--NCVQRVNDFHCECRAGHTGRRCESVING 1310
Score = 64.7 bits (156), Expect = 4e-10
Identities = 59/219 (26%), Positives = 80/219 (36%), Gaps = 39/219 (17%)
Query: 276 PPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHP 334
PP + C SNPC G QC + C CP + +G TC DV+EC P
Sbjct: 130 PPGWSGKSCQQADPCASNPCANGGQCLPFEASYIC-HCPPSF--HGPTCRQDVNECGQKP 186
Query: 335 --CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKS---NKQVC------------ 377
C G C N +RC C TGP + + + S N C
Sbjct: 187 GLCRHGGTCHNEVGSYRC-VCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVTHECAC 245
Query: 378 ----------TDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNP 427
+ID+C C CV+ + +Y C C P +TG C + +
Sbjct: 246 LPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNC-RCPPEWTGQY---CTEDVDECQL 301
Query: 428 ELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVD 466
N C C G CVC GW G+ C +++D
Sbjct: 302 MPNACQNGGTC-HNTHGGYNCVCVNGWTGED--CSENID 337
>gi|4557733 latent transforming growth factor beta binding protein 2
[Homo sapiens]
Length = 1821
Score = 84.0 bits (206), Expect = 6e-16
Identities = 55/189 (29%), Positives = 79/189 (41%), Gaps = 25/189 (13%)
Query: 300 QCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGV----HCINLSPGFRCDACPV 355
+C +S + C C EGY G +C+DV+EC PGV C NL FRC +C
Sbjct: 984 RCVNSPGSYTCLACEEGYRGQSGSCVDVNEC----LTPGVCAHGKCTNLEGSFRC-SCEQ 1038
Query: 356 GFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGY-TGDQ 414
G+ S+++ C D+DEC + A P +C+NT GS+ C C+ GY +
Sbjct: 1039 GYE-----------VTSDEKGCQDVDECASRASCPTGLCLNTEGSFACSACENGYWVNED 1087
Query: 415 IRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEE 474
C+ C P + P V G +C G + D+D D +
Sbjct: 1088 GTACEDLDECAFPGVCPSGV----CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQ 1143
Query: 475 LPCSARNCK 483
C CK
Sbjct: 1144 SSCLGGECK 1152
Score = 73.2 bits (178), Expect = 1e-12
Identities = 62/202 (30%), Positives = 87/202 (43%), Gaps = 28/202 (13%)
Query: 295 CFRGVQCTDSRDGFQCGPCPEGYTGN--GITCIDVDECK--YHPCYPGVHCINLSPGFRC 350
C GV CT++ F C C GY + G +C DVDEC+ C G C N ++C
Sbjct: 1103 CPSGV-CTNTAGSFSCKDCDGGYRPSPLGDSCEDVDECEDPQSSCLGG-ECKNTVGSYQC 1160
Query: 351 DACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGA-CVPNSICVNTLGSYRCGPCKPG 409
CP GF +N VC D++EC C P+ C+N+ GS+ C C PG
Sbjct: 1161 -LCPQGFQ------------LANGTVCEDVNECMGEEHCAPHGECLNSHGSFFC-LCAPG 1206
Query: 410 Y-TGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDID 468
+ + + C+ C + PC V C+ +G C+C G+ G+ VDID
Sbjct: 1207 FVSAEGGTSCQDVDECATTD--PC-VGGHCV-NTEGSFNCLCETGFQPSPE-SGECVDID 1261
Query: 469 SYPDEELP-CSARNCKKDNCKY 489
D P C C+ Y
Sbjct: 1262 ECEDYGDPVCGTWKCENSPGSY 1283
Score = 69.3 bits (168), Expect = 2e-11
Identities = 60/207 (28%), Positives = 80/207 (38%), Gaps = 22/207 (10%)
Query: 259 QACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYT 318
Q ++ + TPST V P +N C G C + DG++C C GY
Sbjct: 820 QGIAEIQEEQVTPSTDVLVTLSTPGIDRCAAGATNVCGPGT-CVNLPDGYRC-VCSPGYQ 877
Query: 319 --GNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN-KQ 375
+ C D +EC PC CIN + C P G + A S Q
Sbjct: 878 LHPSQAYCTDDNECLRDPCKGKGRCINRVGSYSCFCYP-----------GYTLATSGATQ 926
Query: 376 VCTDIDECRNGACVPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVN 435
C DI+EC C NT GSY C C GY + C+ CR+P P +
Sbjct: 927 ECQDINECEQPGVCSGGQCTNTEGSYHC-ECDQGYIMVRKGHCQDINECRHPGTCP---D 982
Query: 436 AQCIEERQGDVTCV-CGVGWAGDGYIC 461
+C+ G TC+ C G+ G C
Sbjct: 983 GRCVNS-PGSYTCLACEEGYRGQSGSC 1008
Score = 67.4 bits (163), Expect = 6e-11
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 23/169 (13%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYT----GNGITCIDVDECKYHPCYPGVHCINLS 345
C +PC +C + + C C GYT G C D++EC+ G C N
Sbjct: 891 CLRDPCKGKGRCINRVGSYSCF-CYPGYTLATSGATQECQDINECEQPGVCSGGQCTNTE 949
Query: 346 PGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGP 405
+ C+ C G+ MV+ K C DI+ECR+ P+ CVN+ GSY C
Sbjct: 950 GSYHCE-CDQGYI--MVR----------KGHCQDINECRHPGTCPDGRCVNSPGSYTCLA 996
Query: 406 CKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW 454
C+ GY G Q C C P + + +C +G C C G+
Sbjct: 997 CEEGYRG-QSGSCVDVNECLTPGV---CAHGKC-TNLEGSFRCSCEQGY 1040
Score = 67.0 bits (162), Expect = 8e-11
Identities = 81/284 (28%), Positives = 111/284 (39%), Gaps = 41/284 (14%)
Query: 300 QCTDSRDGFQCGPCPEGYTG--NGITCIDVDEC-KYHPCYPGVHCINLSPGFRCDACPVG 356
+C +S F C C G+ G +C DVDEC PC G HC+N F C C G
Sbjct: 1191 ECLNSHGSFFC-LCAPGFVSAEGGTSCQDVDECATTDPCVGG-HCVNTEGSFNC-LCETG 1247
Query: 357 FTGPMVQGVGISFAKSNKQVCTDIDECRN-GACVPNS-ICVNTLGSYRCG-PCKPGYTGD 413
F G C DIDEC + G V + C N+ GSYRC C+PG+
Sbjct: 1248 FQPSPESG-----------ECVDIDECEDYGDPVCGTWKCENSPGSYRCVLGCQPGFHMA 1296
Query: 414 QIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGW--AGDGYICGKDVDIDSYP 471
C C N + C + C + G C+C G+ + G+ C VD++
Sbjct: 1297 PNGDCIDIDECANDTM--CGSHGFC-DNTDGSFRCLCDQGFEISPSGWDC---VDVNECE 1350
Query: 472 DEELPCSARNCKKDNCKYVPNSGQEDADRDGIGDACDEDADGDGILNEQ---DNCVLIHN 528
C A C+ ++ + + D C G ++E D+
Sbjct: 1351 LMLAVCGAALCENVEGSFLCLCASDLEEYDAQEGHCRPRGAGGQSMSEAPTGDHAPAPTR 1410
Query: 529 VDQRNSDKDIFGDACDNCLSVL--NNDQKD---TDGDGRGDACD 567
+D + K G A C SVL N Q + T G GDACD
Sbjct: 1411 MDCYSGQK---GHA--PCSSVLGRNTTQAECCCTQGASWGDACD 1449
Score = 45.8 bits (107), Expect = 2e-04
Identities = 34/90 (37%), Positives = 43/90 (47%), Gaps = 16/90 (17%)
Query: 326 DVDECK-YHP-CYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC 383
D DEC + P P C+N PG+ C P G + S+K+ C D DEC
Sbjct: 1485 DADECVIFGPGLCPNGRCLNTVPGYVCLCNP-----------GFHYDASHKK-CEDHDEC 1532
Query: 384 RNGACVPNSICVNTLGSYRCGPCKPGYTGD 413
++ AC N CVNT GS+ C C P T D
Sbjct: 1533 QDLAC-ENGECVNTEGSFHCF-CSPPLTLD 1560
Score = 41.6 bits (96), Expect = 0.004
Identities = 31/104 (29%), Positives = 42/104 (40%), Gaps = 22/104 (21%)
Query: 314 PEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSN 373
P G+ G + +EC C+ + G+ CD C GF +
Sbjct: 1726 PAGFEG-----LQAEECGILNGCENGRCVRVREGYTCD-CFEGFQ-----------LDAA 1768
Query: 374 KQVCTDIDECR--NGACV--PNSICVNTLGSYRCGPCKPGYTGD 413
C D++EC NG V + C NT GSYRC C PGY +
Sbjct: 1769 HMACVDVNECDDLNGPAVLCVHGYCENTEGSYRC-HCSPGYVAE 1811
Score = 40.8 bits (94), Expect = 0.006
Identities = 23/71 (32%), Positives = 34/71 (47%), Gaps = 5/71 (7%)
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQV----CTDIDECRNGACVPNSICVNTLGSYRCGP 405
C CP P+++ + + K++ C DI+EC ++ CVNT GSY C
Sbjct: 589 CAPCPPRPASPVIENGQLECPQGYKRLNLTHCQDINECLTLGLCKDAECVNTRGSYLC-T 647
Query: 406 CKPGYTGDQIR 416
C+PG D R
Sbjct: 648 CRPGLMLDPSR 658
>gi|21704277 jagged 2 isoform a precursor [Homo sapiens]
Length = 1238
Score = 84.0 bits (206), Expect = 6e-16
Identities = 64/207 (30%), Positives = 86/207 (41%), Gaps = 38/207 (18%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S+PC G C D DGF C CP+G++G + +DVD C+ PC G C NL +
Sbjct: 502 CASSPCHSGGLCEDLADGFHCH-CPQGFSGP-LCEVDVDLCEPSPCRNGARCYNLEGDYY 559
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDEC------------RNGACVPNSICVNT 397
C ACP F G + + C ID C +G C P+ CV+
Sbjct: 560 C-ACPDDFGG---KNCSVPREPCPGGACRVIDGCGSDAGPGMPGTAASGVCGPHGRCVSQ 615
Query: 398 LGSYRCGPCKPGYTG----DQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVG 453
G C G+TG + I C + PC CI+E C C G
Sbjct: 616 PGGNFSCICDSGFTGTYCHENIDDCLGQ---------PCRNGGTCIDEVDA-FRCFCPSG 665
Query: 454 WAGDGYICGKDVDIDSYPDEELPCSAR 480
W G+ +C + + D PD PC +R
Sbjct: 666 WEGE--LCDTNPN-DCLPD---PCHSR 686
Score = 80.1 bits (196), Expect = 9e-15
Identities = 59/180 (32%), Positives = 83/180 (46%), Gaps = 31/180 (17%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C SNPC G C D DGF+C CPE + G TC +D +EC+ PC C NL G+
Sbjct: 389 CASNPCAAGGTCVDQVDGFEC-ICPEQWV--GATCQLDANECEGKPCLNAFSCKNLIGGY 445
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
CD P G+ G ++++CR G C C + + Y+C C
Sbjct: 446 YCDCIP-GWKGINCH--------------INVNDCR-GQCQHGGTCKDLVNGYQC-VCPR 488
Query: 409 GYTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDI 467
G+ G R C+ ER+ C + +PC C E+ C C G++G +C DVD+
Sbjct: 489 GFGG---RHCELERDECAS---SPCHSGGLC-EDLADGFHCHCPQGFSGP--LCEVDVDL 539
Score = 79.7 bits (195), Expect = 1e-14
Identities = 56/169 (33%), Positives = 72/169 (42%), Gaps = 29/169 (17%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITC-IDVDECKYHPCYPGVHCINLSPGF 348
C SNPC G C + GF+C CP G++G TC +D+DEC +PC G C++ GF
Sbjct: 351 CTSNPCANGGSCHEVPSGFECH-CPSGWSGP--TCALDIDECASNPCAAGGTCVDQVDGF 407
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
C CP + G Q D +EC C+ C N +G Y C C P
Sbjct: 408 EC-ICPEQWVGATCQ--------------LDANECEGKPCLNAFSCKNLIGGYYC-DCIP 451
Query: 409 GYTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
G+ G C N CR C C + G CVC G+ G
Sbjct: 452 GWKG---INCHINVNDCR----GQCQHGGTCKDLVNG-YQCVCPRGFGG 492
Score = 75.5 bits (184), Expect = 2e-13
Identities = 50/169 (29%), Positives = 71/169 (42%), Gaps = 25/169 (14%)
Query: 289 RCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGF 348
+CD+ C G C DS D F+C CP G+ G+ C +PC G C+ F
Sbjct: 715 QCDAYTCSNGGTCYDSGDTFRCA-CPPGWKGSTCAVAKNSSCLPNPCVNGGTCVGSGASF 773
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCT-DIDECRNGACVPNSICVNTLGSYRCGPCK 407
C C G+ G + CT + ++C C ICV+ + +RC C
Sbjct: 774 SC-ICRDGWEG---------------RTCTHNTNDCNPLPCYNGGICVDGVNWFRC-ECA 816
Query: 408 PGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
PG+ G R N + +PC+ A C++E G C C G AG
Sbjct: 817 PGFAGPDCR-----INIDECQSSPCAYGATCVDEING-YRCSCPPGRAG 859
Score = 59.3 bits (142), Expect = 2e-08
Identities = 32/83 (38%), Positives = 45/83 (54%), Gaps = 4/83 (4%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C+ PC+ G C D + F+C C G+ G I++DEC+ PC G C++ G+R
Sbjct: 793 CNPLPCYNGGICVDGVNWFRC-ECAPGFAGPDCR-INIDECQSSPCAYGATCVDEINGYR 850
Query: 350 CDACPVGFTGPMVQGVGISFAKS 372
C +CP G GP Q V I F +S
Sbjct: 851 C-SCPPGRAGPRCQEV-IGFGRS 871
Score = 50.4 bits (119), Expect = 8e-06
Identities = 53/201 (26%), Positives = 81/201 (40%), Gaps = 37/201 (18%)
Query: 288 RRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDEC-KYHPCYPGVHCINLS 345
R CD + G + +QC C + G+ C D++ C +HPC G CIN
Sbjct: 271 RFCDECVPYPGCVHGSCVEPWQCN-CETNW--GGLLCDKDLNYCGSHHPCTNGGTCINAE 327
Query: 346 PG-FRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCG 404
P +RC CP G++G + + CT + C NG C + C
Sbjct: 328 PDQYRC-TCPDGYSG--------RNCEKAEHACTS-NPCANGGS-----CHEVPSGFEC- 371
Query: 405 PCKPGYTGDQIRGCKAE-RNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGK 463
C G++G C + C + NPC+ C+++ G C+C W G
Sbjct: 372 HCPSGWSGPT---CALDIDECAS---NPCAAGGTCVDQVDG-FECICPEQWV------GA 418
Query: 464 DVDIDSYPDEELPC-SARNCK 483
+D+ E PC +A +CK
Sbjct: 419 TCQLDANECEGKPCLNAFSCK 439
>gi|55770876 notch4 preproprotein [Homo sapiens]
Length = 2003
Score = 84.0 bits (206), Expect = 6e-16
Identities = 67/229 (29%), Positives = 90/229 (39%), Gaps = 36/229 (15%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C +PC C DS G +C CP GYTG + +D C PC HC+ P F
Sbjct: 810 CADSPCRNRATCQDSPQGPRC-LCPTGYTGGSCQTL-MDLCAQKPCPRNSHCLQTGPSFH 867
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDE-CRNGACVPNSICVNTLGSYRCGPCKP 408
C C G+TGP+ S K+ D+ C NG +CV++ SY C C P
Sbjct: 868 C-LCLQGWTGPLCNLPLSSCQKAALSQGIDVSSLCHNG-----GLCVDSGPSYFC-HCPP 920
Query: 409 GYTG----DQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKD 464
G+ G D + C E PC A C+ + G C C G+ DG C K+
Sbjct: 921 GFQGSLCQDHVNPC---------ESRPCQNGATCMAQPSG-YLCQCAPGY--DGQNCSKE 968
Query: 465 VDIDSYPDEELPCSARNC-KKDNCKYVPNSGQEDADRDGIGDACDEDAD 512
+D C ++ C C P +G C+ D D
Sbjct: 969 LD---------ACQSQPCHNHGTCTPKPGGFHCACPPGFVGLRCEGDVD 1008
Score = 82.4 bits (202), Expect = 2e-15
Identities = 75/269 (27%), Positives = 108/269 (40%), Gaps = 63/269 (23%)
Query: 293 NPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDA 352
+PC G C ++ F C CP GYTG+ D +EC PC+PG C++L F C
Sbjct: 444 SPCEHGGSCLNTPGSFNC-LCPPGYTGSRCEA-DHNECLSQPCHPGSTCLDLLATFHC-L 500
Query: 353 CPVGFTGPMVQGVGISFAKS---NKQVC---------------------TDIDECRNGAC 388
CP G G + + A + N C DIDECR+ C
Sbjct: 501 CPPGLEGQLCEVETNECASAPCLNHADCHDLLNGFQCICLPGFSGTRCEEDIDECRSSPC 560
Query: 389 VPNSICVNTLGSYRCGPCKPGYTGDQIRGCKAE-RNCRNPELNPCSVNAQCIEERQGDVT 447
C + G++ C C PG+ G + C+ E C + +PC V A C+ + G
Sbjct: 561 ANGGQCQDQPGAFHC-KCLPGFEGPR---CQTEVDECLS---DPCPVGASCL-DLPGAFF 612
Query: 448 CVCGVGWAGDGYICGKDVDIDSYPDEELP-CSARNCK-KDNCKYVPNSGQEDADRDGIGD 505
C+C G+ G +C E+P C+ C+ K CK +D
Sbjct: 613 CLCPSGFTGQ--LC------------EVPLCAPNLCQPKQICK---------DQKDKANC 649
Query: 506 ACDEDADGDGILNEQDNCVLIHNVDQRNS 534
C + + G +DNC H QR+S
Sbjct: 650 LCPDGS--PGCAPPEDNCTCHHGHCQRSS 676
Score = 79.3 bits (194), Expect = 2e-14
Identities = 57/187 (30%), Positives = 79/187 (42%), Gaps = 38/187 (20%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S PC C D +GFQC C G++G D+DEC+ PC G C + F
Sbjct: 517 CASAPCLNHADCHDLLNGFQC-ICLPGFSGTRCE-EDIDECRSSPCANGGQCQDQPGAFH 574
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C P GF GP Q T++DEC + C + C++ G++ C C G
Sbjct: 575 CKCLP-GFEGPRCQ--------------TEVDECLSDPCPVGASCLDLPGAFFC-LCPSG 618
Query: 410 YTGD--QIRGC--------------KAERNCRNPELNP-CSV---NAQCIEERQGDVTCV 449
+TG ++ C K + NC P+ +P C+ N C +CV
Sbjct: 619 FTGQLCEVPLCAPNLCQPKQICKDQKDKANCLCPDGSPGCAPPEDNCTCHHGHCQRSSCV 678
Query: 450 CGVGWAG 456
C VGW G
Sbjct: 679 CDVGWTG 685
Score = 78.6 bits (192), Expect = 3e-14
Identities = 56/168 (33%), Positives = 70/168 (41%), Gaps = 25/168 (14%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDECKYHPCYPGVHCINLSPGF 348
C S PC G C G+ C CP GYTG TC ++ C PC G C N SPG
Sbjct: 695 CISAPCAHGGTCYPQPSGYNC-TCPTGYTGP--TCSEEMTACHSGPCLNGGSC-NPSPGG 750
Query: 349 RCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKP 408
CP TGP Q T D C + C CVN G++ C C
Sbjct: 751 YYCTCPPSHTGPQCQ--------------TSTDYCVSAPCFNGGTCVNRPGTFSC-LCAM 795
Query: 409 GYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
G+ G + G K +C + +PC A C + QG C+C G+ G
Sbjct: 796 GFQGPRCEG-KLRPSCAD---SPCRNRATCQDSPQGP-RCLCPTGYTG 838
Score = 76.6 bits (187), Expect = 1e-13
Identities = 58/184 (31%), Positives = 80/184 (43%), Gaps = 30/184 (16%)
Query: 287 PRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHP---CYPGVHCIN 343
P C S+ C G C D D + C CPE +TG + DVDEC+ C G C N
Sbjct: 277 PDNCVSHQCQNGGTCQDGLDTYTC-LCPETWTGWDCS-EDVDECETQGPPHCRNGGTCQN 334
Query: 344 LSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRC 403
+ F C C G+ G + ++D+C C P S C++ +GS+ C
Sbjct: 335 SAGSFHC-VCVSGWGGTSCE--------------ENLDDCIAATCAPGSTCIDRVGSFSC 379
Query: 404 GPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQC-IEERQGDVTCVCGVGWAGDGYICG 462
C PG TG C E C + PC +AQC G C+C G++G C
Sbjct: 380 -LCPPGRTG---LLCHLEDMCLS---QPCHGDAQCSTNPLTGSTLCLCQPGYSGP--TCH 430
Query: 463 KDVD 466
+D+D
Sbjct: 431 QDLD 434
Score = 69.3 bits (168), Expect = 2e-11
Identities = 53/168 (31%), Positives = 68/168 (40%), Gaps = 25/168 (14%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFR 349
C S PC G C S G+ C CP +TG D C PC+ G C+N F
Sbjct: 733 CHSGPCLNGGSCNPSPGGYYC-TCPPSHTGPQCQ-TSTDYCVSAPCFNGGTCVNRPGTFS 790
Query: 350 CDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGSYRCGPCKPG 409
C C +GF GP +G + C D CRN A C ++ RC C G
Sbjct: 791 C-LCAMGFQGPRCEG-------KLRPSCAD-SPCRNRA-----TCQDSPQGPRC-LCPTG 835
Query: 410 YTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAG 456
YTG C+ + C PC N+ C++ C+C GW G
Sbjct: 836 YTGG---SCQTLMDLCAQ---KPCPRNSHCLQTGP-SFHCLCLQGWTG 876
Score = 59.3 bits (142), Expect = 2e-08
Identities = 70/273 (25%), Positives = 96/273 (35%), Gaps = 94/273 (34%)
Query: 258 CQACGPLKFQSPTPSTVVPPAPPAPPTRPPRRCDSNPCFRGVQCTDSRDGFQCGP----- 312
CQ G + P P + P+ P+P T P C P F G +C + C P
Sbjct: 74 CQNGGSCQALLPAPLGL--PSSPSPLT-PSFLCTCLPGFTGERCQAKLED-PCPPSFCSK 129
Query: 313 ---------------CPEGYTGNGITCIDVDECKYHPCYPGVHCINLSPGFRCDACPVGF 357
C G+TG C D C +PC G C+ P +C CP GF
Sbjct: 130 RGRCHIQASGRPQCSCMPGWTGE--QCQLRDFCSANPCVNGGVCLATYPQIQCH-CPPGF 186
Query: 358 TGPMVQGVGISFAKSNKQVCTDIDECRN--GACVPNSICVNTLGSYRC------------ 403
G + D++EC G C + C NTLGS++C
Sbjct: 187 EGHACE--------------RDVNECFQDPGPCPKGTSCHNTLGSFQCLCPVGQEGPRCE 232
Query: 404 ---GPCKPGYTGDQIRGCKAERNCR---------------------NPELNPCS-VNAQC 438
GPC P RGC C+ + E+NP + V+ QC
Sbjct: 233 LRAGPCPP-------RGCSNGGTCQLMPEKDSTFHLCLCPPGFIGPDCEVNPDNCVSHQC 285
Query: 439 -----IEERQGDVTCVCGVGWAGDGYICGKDVD 466
++ TC+C W G+ C +DVD
Sbjct: 286 QNGGTCQDGLDTYTCLCPETWT--GWDCSEDVD 316
Score = 57.8 bits (138), Expect = 5e-08
Identities = 71/272 (26%), Positives = 84/272 (30%), Gaps = 94/272 (34%)
Query: 290 CDSNPCFRGVQCTDSRDGFQCGPCPEGYTGNGITCI-DVDECKYHPCYP--GVHCINLSP 346
C S PC CT GF C CP G+ G + C DVDEC PC+P C +L+
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHCA-CPPGFVG--LRCEGDVDECLDQPCHPTGTAACHSLAN 1028
Query: 347 GFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSICVNTLGS---YRC 403
F C P G TG + +ID C + C C T GS + C
Sbjct: 1029 AFYCQCLP-GHTGQWCE--------------VEIDPCHSQPCFHGGTCEATAGSPLGFIC 1073
Query: 404 -------GP---------------------------------CKPGYTGDQIRGCKAERN 423
GP C GY G A +
Sbjct: 1074 HCPKGFEGPTCSHRAPSCGFHHCHHGGLCLPSPKPGFPPRCACLSGYGGPDCLTPPAPKG 1133
Query: 424 CRNPELNPCSVNAQCIEERQGDVTCVCGVGWAGDGYICGKDVDIDSYPDEELPCSARNCK 483
C P +PC N C E G G G+ C S P C+
Sbjct: 1134 CGPP--SPCLYNGSCSET----------TGLGGPGFRC-------SCPHSS---PGPRCQ 1171
Query: 484 KDNCKYVPNSGQEDADRDGIGDACDEDADGDG 515
K K G E DG ACD G G
Sbjct: 1172 KPGAK-----GCEGRSGDG---ACDAGCSGPG 1195
Score = 56.2 bits (134), Expect = 1e-07
Identities = 53/193 (27%), Positives = 74/193 (38%), Gaps = 45/193 (23%)
Query: 286 PPRRCDSNPCFRGVQCTDSRDGFQCGPCPEGYT----GNGITC------------IDVDE 329
P C P F+G C D + + PC G T +G C ++D
Sbjct: 912 PSYFCHCPPGFQGSLCQDHVNPCESRPCQNGATCMAQPSGYLCQCAPGYDGQNCSKELDA 971
Query: 330 CKYHPCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACV 389
C+ PC+ C GF C ACP GF G +G D+DEC + C
Sbjct: 972 CQSQPCHNHGTCTPKPGGFHC-ACPPGFVGLRCEG--------------DVDECLDQPCH 1016
Query: 390 P--NSICVNTLGSYRCGPCKPGYTGDQIRGCKAERN-CRNPELNPCSVNAQCIEERQGD- 445
P + C + ++ C C PG+TG + C+ E + C + PC C E G
Sbjct: 1017 PTGTAACHSLANAFYC-QCLPGHTG---QWCEVEIDPCHS---QPCFHGGTC-EATAGSP 1068
Query: 446 --VTCVCGVGWAG 456
C C G+ G
Sbjct: 1069 LGFICHCPKGFEG 1081
Score = 43.9 bits (102), Expect = 7e-04
Identities = 37/129 (28%), Positives = 56/129 (43%), Gaps = 15/129 (11%)
Query: 334 PCYPGVHCINLSPGFRCDACPVGFTGPMVQGVGISFAKSNKQVCTDIDECRNGACVPNSI 393
PC G C++LS G C GF G Q N Q+C + C+ A +P +
Sbjct: 34 PCANGGTCLSLSLGQGTCQCAPGFLGETCQ---FPDPCQNAQLCQNGGSCQ--ALLPAPL 88
Query: 394 CVNT-----LGSYRCGPCKPGYTGDQIRGCKAERNCRNPELNPCSVNAQCIEERQGDVTC 448
+ + S+ C C PG+TG++ C+A+ P + CS +C + G C
Sbjct: 89 GLPSSPSPLTPSFLC-TCLPGFTGER---CQAKLEDPCPP-SFCSKRGRCHIQASGRPQC 143
Query: 449 VCGVGWAGD 457
C GW G+
Sbjct: 144 SCMPGWTGE 152
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.138 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 43,411,508
Number of Sequences: 37866
Number of extensions: 2349389
Number of successful extensions: 16306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 242
Number of HSP's that attempted gapping in prelim test: 12628
Number of HSP's gapped (non-prelim): 1791
length of query: 961
length of database: 18,247,518
effective HSP length: 112
effective length of query: 849
effective length of database: 14,006,526
effective search space: 11891540574
effective search space used: 11891540574
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.