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Search of human proteins with 31542255
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|31542255 hypothetical protein LOC140706 [Homo sapiens]
(433 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|31542255 hypothetical protein LOC140706 [Homo sapiens] 908 0.0
gi|13899275 cerebral cavernous malformation 2 isoform 2 [Homo sa... 146 3e-35
gi|71067341 cerebral cavernous malformation 2 isoform 1 [Homo sa... 137 1e-32
gi|109452587 family with sequence similarity 98, member B isofor... 54 4e-07
gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a ... 50 3e-06
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 48 2e-05
gi|119395750 keratin 1 [Homo sapiens] 47 4e-05
gi|47132620 keratin 2 [Homo sapiens] 47 4e-05
gi|59806361 hypothetical protein LOC387104 [Homo sapiens] 46 6e-05
gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo sapi... 46 6e-05
gi|55956899 keratin 9 [Homo sapiens] 46 8e-05
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 46 8e-05
gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 45 1e-04
gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1 iso... 45 1e-04
gi|126090909 engrailed homeobox 1 [Homo sapiens] 45 2e-04
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 45 2e-04
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens] 45 2e-04
gi|195972866 keratin 10 [Homo sapiens] 44 2e-04
gi|119395716 forkhead box C1 [Homo sapiens] 44 4e-04
gi|9966841 cell death regulator aven [Homo sapiens] 43 5e-04
gi|84570137 homeobox B3 [Homo sapiens] 43 5e-04
gi|122937261 coiled-coil domain containing 85A [Homo sapiens] 43 5e-04
gi|29029632 anaplastic lymphoma kinase [Homo sapiens] 43 6e-04
gi|239750846 PREDICTED: hypothetical protein [Homo sapiens] 43 6e-04
gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo ... 43 6e-04
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 43 6e-04
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 43 6e-04
gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precurs... 43 6e-04
gi|109255251 loricrin [Homo sapiens] 42 8e-04
>gi|31542255 hypothetical protein LOC140706 [Homo sapiens]
Length = 433
Score = 908 bits (2346), Expect = 0.0
Identities = 433/433 (100%), Positives = 433/433 (100%)
Query: 1 MEYEVKKGKKGFVSPIRRLVFPKAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDY 60
MEYEVKKGKKGFVSPIRRLVFPKAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDY
Sbjct: 1 MEYEVKKGKKGFVSPIRRLVFPKAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDY 60
Query: 61 LEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLL 120
LEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLL
Sbjct: 61 LEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLL 120
Query: 121 TWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPP 180
TWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPP
Sbjct: 121 TWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPP 180
Query: 181 GGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERR 240
GGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERR
Sbjct: 181 GGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERR 240
Query: 241 QTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGPNPLDPQDPSPDAY 300
QTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGPNPLDPQDPSPDAY
Sbjct: 241 QTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGPNPLDPQDPSPDAY 300
Query: 301 CNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRIMAP 360
CNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRIMAP
Sbjct: 301 CNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTPERPWLCSRIMAP 360
Query: 361 RTPLKHVTAARPHLLSMAPTAAAATTAVWAWSSYRITWSRCGVSWGPSRSSSLRCCCGST 420
RTPLKHVTAARPHLLSMAPTAAAATTAVWAWSSYRITWSRCGVSWGPSRSSSLRCCCGST
Sbjct: 361 RTPLKHVTAARPHLLSMAPTAAAATTAVWAWSSYRITWSRCGVSWGPSRSSSLRCCCGST 420
Query: 421 GWGCPSRTIAQAC 433
GWGCPSRTIAQAC
Sbjct: 421 GWGCPSRTIAQAC 433
>gi|13899275 cerebral cavernous malformation 2 isoform 2 [Homo
sapiens]
Length = 444
Score = 146 bits (369), Expect = 3e-35
Identities = 82/166 (49%), Positives = 110/166 (66%), Gaps = 6/166 (3%)
Query: 1 MEYEVKKGKK-GFVSPIRRLVFP--KAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILL 57
ME E KKGKK G VSP +R+ K+ + A RRPLH++ L P+ ++P LL
Sbjct: 1 MEEEGKKGKKPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPER-VEPDRLL 59
Query: 58 CDYLEKEVKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARC 117
DY+EKEVK+LG LT + LNPSSR E+L +D A++ +LP T E D++LSLSA
Sbjct: 60 SDYIEKEVKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYN 119
Query: 118 LLLTWRDNEELILRIPTHEIAAASYLQDDALHLLVLKTGL--GVDP 161
+ L WRD E++ILR+P H+IAA SY++DDA HL+VLKT G+ P
Sbjct: 120 VKLAWRDGEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISP 165
Score = 50.4 bits (119), Expect = 3e-06
Identities = 25/52 (48%), Positives = 35/52 (67%)
Query: 297 PDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTP 348
P C LVILA ++ AAEE C L+ QVFQ++Y + +I+ +DRA + STP
Sbjct: 189 PVEACCLVILAAESKVAAEELCCLLGQVFQVVYTESTIDFLDRAIFDGASTP 240
>gi|71067341 cerebral cavernous malformation 2 isoform 1 [Homo
sapiens]
Length = 465
Score = 137 bits (346), Expect = 1e-32
Identities = 74/159 (46%), Positives = 104/159 (65%), Gaps = 5/159 (3%)
Query: 7 KGKKGFVSPIRRLVFP--KAGRRAACRSSVSRRPLHSMPLYPPDYLIDPQILLCDYLEKE 64
+ + G VSP +R+ K+ + A RRPLH++ L P+ ++P LL DY+EKE
Sbjct: 29 ENEPGIVSPFKRVFLKGEKSRDKKAHEKVTERRPLHTVVLSLPER-VEPDRLLSDYIEKE 87
Query: 65 VKFLGHLTWVTSSLNPSSRDELLQLLDTARQLKELPLKTTAEQDSILSLSARCLLLTWRD 124
VK+LG LT + LNPSSR E+L +D A++ +LP T E D++LSLSA + L WRD
Sbjct: 88 VKYLGQLTSIPGYLNPSSRTEILHFIDNAKRAHQLPGHLTQEHDAVLSLSAYNVKLAWRD 147
Query: 125 NEELILRIPTHEIAAASYLQDDALHLLVLKTGL--GVDP 161
E++ILR+P H+IAA SY++DDA HL+VLKT G+ P
Sbjct: 148 GEDIILRVPIHDIAAVSYVRDDAAHLVVLKTAQDPGISP 186
Score = 50.4 bits (119), Expect = 3e-06
Identities = 25/52 (48%), Positives = 35/52 (67%)
Query: 297 PDAYCNLVILAVANRDAAEESCALICQVFQIIYGDQSIECVDRAGYHYTSTP 348
P C LVILA ++ AAEE C L+ QVFQ++Y + +I+ +DRA + STP
Sbjct: 210 PVEACCLVILAAESKVAAEELCCLLGQVFQVVYTESTIDFLDRAIFDGASTP 261
>gi|109452587 family with sequence similarity 98, member B isoform 1
[Homo sapiens]
Length = 433
Score = 53.5 bits (127), Expect = 4e-07
Identities = 38/112 (33%), Positives = 42/112 (37%), Gaps = 22/112 (19%)
Query: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAG 230
GG GR G GG R GWGGG GGGGGG G
Sbjct: 343 GGGGRGGGGGGGG--------------------RGGWGGGGGGWGGGGGGGGGWGGGGGG 382
Query: 231 ARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWER 282
R G ++ R + G GG GG G G P G G GGGG + R
Sbjct: 383 GR--GGFQGRGDYGGRGGYGGRGGYGGRGYGDPYGGGGGGGGGGGGGGGYRR 432
Score = 52.0 bits (123), Expect = 1e-06
Identities = 49/144 (34%), Positives = 55/144 (38%), Gaps = 27/144 (18%)
Query: 154 KTGLGVDPVPAGVDASPGGAGRD--PGPPGGAP-EKRRVGTAERRHTICSLDWRMGWGGG 210
KT ++ V G GG + P PP P +KR+ G R GWGGG
Sbjct: 292 KTACAINKVLMGRVPDRGGRPNEIEPPPPEMPPWQKRQEGGGGRG----------GWGGG 341
Query: 211 AAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGG--GGGAGKPGGSWE 268
GGGGGG G R G W G W GGGGG GGG G GG
Sbjct: 342 GGGGGRGGGGGG-------GGR--GGWGGG---GGGWGGGGGGGGGWGGGGGGGRGGFQG 389
Query: 269 RRQAGSGGGGSWERRHPGPNPLDP 292
R G GG + G DP
Sbjct: 390 RGDYGGRGGYGGRGGYGGRGYGDP 413
>gi|52632383 heterogeneous nuclear ribonucleoprotein L isoform a
[Homo sapiens]
Length = 589
Score = 50.4 bits (119), Expect = 3e-06
Identities = 36/103 (34%), Positives = 46/103 (44%), Gaps = 13/103 (12%)
Query: 185 EKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFS 244
EKRR +R+ + R G A AGGGGGG R G G +R
Sbjct: 10 EKRRRRLEQRQQPD---EQRRRSGAMVKMAAAGGGGGGG--RYYGGGSEGGRAPKRLKTD 64
Query: 245 GSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGP 287
+ ++ GGGGGGGGAG G G GGG +++ H P
Sbjct: 65 NAGDQHGGGGGGGGGAGAAG--------GGGGGENYDDPHKTP 99
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 48.1 bits (113), Expect = 2e-05
Identities = 28/71 (39%), Positives = 34/71 (47%), Gaps = 12/71 (16%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW 267
GG + ++GGGG G +Q G R G SG GGGGGGGG + G +
Sbjct: 192 GGYGNQDQSGGGGSGGYGQQDRGGRGRGG-------SGG-----GGGGGGGGYNRSSGGY 239
Query: 268 ERRQAGSGGGG 278
E R G G GG
Sbjct: 240 EPRGRGGGRGG 250
Score = 41.2 bits (95), Expect = 0.002
Identities = 25/96 (26%), Positives = 36/96 (37%), Gaps = 21/96 (21%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGS------------------- 246
G+G A + G G S + G SGS+ ++ ++ G
Sbjct: 99 GYGQQPAPSSTSGSYGSSSQSSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQ 158
Query: 247 --WERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSW 280
+ GGGGGGGG G G +G G GG +
Sbjct: 159 NQYNSSSGGGGGGGGGGNYGQDQSSMSSGGGSGGGY 194
Score = 39.7 bits (91), Expect = 0.005
Identities = 27/86 (31%), Positives = 36/86 (41%), Gaps = 14/86 (16%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW 267
GGG GGGGGG+ + ++ + G + G + GGGG GG G+
Sbjct: 166 GGGG-----GGGGGGNYGQDQSSMSSGGG-----SGGGYGNQDQSGGGGSGGYGQQDRGG 215
Query: 268 ERRQA----GSGGGGSWERRHPGPNP 289
R G GGGG + R G P
Sbjct: 216 RGRGGSGGGGGGGGGGYNRSSGGYEP 241
Score = 37.7 bits (86), Expect = 0.020
Identities = 35/121 (28%), Positives = 42/121 (34%), Gaps = 14/121 (11%)
Query: 165 GVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTIC---SLDWRM-----------GWGGG 210
G + GG G P GG ++R G + + C + WR G GGG
Sbjct: 399 GGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRNECNQCKAPKPDGPGGG 458
Query: 211 AAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERR 270
+ GG G R G G R G R GG GG G GK E R
Sbjct: 459 PGGSHMGGNYGDDRRGGRGGYDRGGYRGRGGDRGGFRGGRGGGDRGGFGPGKMDSRGEHR 518
Query: 271 Q 271
Q
Sbjct: 519 Q 519
Score = 36.2 bits (82), Expect = 0.060
Identities = 28/96 (29%), Positives = 35/96 (36%), Gaps = 23/96 (23%)
Query: 204 RMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWE--------------- 248
R G G G R G GGGGS R G + G Q +G W+
Sbjct: 383 RGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCPNPTCENMNFSWRN 442
Query: 249 --------RRHGGGGGGGGAGKPGGSWERRQAGSGG 276
+ G GGG GG+ G + R+ G GG
Sbjct: 443 ECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRGG 478
Score = 35.0 bits (79), Expect = 0.13
Identities = 25/63 (39%), Positives = 28/63 (44%), Gaps = 18/63 (28%)
Query: 204 RMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKP 263
R G G G + GGGGGG R+SG +E R G GGG GG G
Sbjct: 213 RGGRGRGGSGGGGGGGGGGY-------NRSSGGYEPR-----------GRGGGRGGRGGM 254
Query: 264 GGS 266
GGS
Sbjct: 255 GGS 257
Score = 33.5 bits (75), Expect = 0.39
Identities = 25/74 (33%), Positives = 29/74 (39%), Gaps = 22/74 (29%)
Query: 218 GGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
GGG G R R G G + GGGG GG G+ G +G GGG
Sbjct: 378 GGGNGRGGRGRGGPMGRGGY---------------GGGGSGGGGRGG-----FPSGGGGG 417
Query: 278 GSWERRHPG--PNP 289
G +R PNP
Sbjct: 418 GGQQRAGDWKCPNP 431
Score = 32.7 bits (73), Expect = 0.66
Identities = 20/65 (30%), Positives = 24/65 (36%), Gaps = 9/65 (13%)
Query: 204 RMGWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKP 263
R + G R G G GG + R G SG G GGGGGG +
Sbjct: 372 RADFNRGGGNGRGGRGRGGPMGRGGYGGGGSG---------GGGRGGFPSGGGGGGGQQR 422
Query: 264 GGSWE 268
G W+
Sbjct: 423 AGDWK 427
Score = 31.2 bits (69), Expect = 1.9
Identities = 21/60 (35%), Positives = 26/60 (43%), Gaps = 12/60 (20%)
Query: 231 ARASGSWERRQTFSGS------------WERRHGGGGGGGGAGKPGGSWERRQAGSGGGG 278
A+A+ W + FSG+ + R G G GG G G P G GSGGGG
Sbjct: 347 AKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGGSGGGG 406
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 46.6 bits (109), Expect = 4e-05
Identities = 33/87 (37%), Positives = 39/87 (44%), Gaps = 4/87 (4%)
Query: 196 HTICSLDWRMGWGGGA--AEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGG 253
HT S G GGG + + G GGGS G GS+ + GS +G
Sbjct: 509 HTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGS 568
Query: 254 GGGGGGAGK--PGGSWERRQAGSGGGG 278
GGGGGG G G S + GSGGGG
Sbjct: 569 GGGGGGHGSYGSGSSSGGYRGGSGGGG 595
Score = 42.7 bits (99), Expect = 6e-04
Identities = 28/82 (34%), Positives = 34/82 (41%), Gaps = 9/82 (10%)
Query: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG--GAGKPG 264
+G G +GGGGGG +G + GS G GGGGG G G+G
Sbjct: 532 YGSGGGSYGSGGGGGGGRGSYGSGGSSYGS-------GGGSYGSGGGGGGHGSYGSGSSS 584
Query: 265 GSWERRQAGSGGGGSWERRHPG 286
G + G GGG S R G
Sbjct: 585 GGYRGGSGGGGGGSSGGRGSGG 606
Score = 39.7 bits (91), Expect = 0.005
Identities = 34/103 (33%), Positives = 40/103 (38%), Gaps = 24/103 (23%)
Query: 194 RRHTICSLDWRMGWGGGAAEARAGGGG----------------GGSLERQRAGARASGSW 237
+R T S R G GGG + GGGG GGS + AR G
Sbjct: 28 QRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGG-- 85
Query: 238 ERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSW 280
R F G + GGGG GG G GG + G GG G +
Sbjct: 86 -RGSGFGGGY-----GGGGFGGGGFGGGGFGGGGIGGGGFGGF 122
Score = 39.7 bits (91), Expect = 0.005
Identities = 30/74 (40%), Positives = 31/74 (41%), Gaps = 4/74 (5%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G GGG R G GGS G+ SG GS G GG GG G GG
Sbjct: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG--GG 597
Query: 266 SWERRQAGSGGGGS 279
S R GSGGG S
Sbjct: 598 SSGGR--GSGGGSS 609
Score = 39.3 bits (90), Expect = 0.007
Identities = 32/84 (38%), Positives = 36/84 (42%), Gaps = 24/84 (28%)
Query: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG-------G 259
+G G +GGGGGG G+ SGS S R GGGGGG G
Sbjct: 559 YGSGGGSYGSGGGGGGH------GSYGSGS-------SSGGYRGGSGGGGGGSSGGRGSG 605
Query: 260 AGKPGGSWERRQAGSGG----GGS 279
G GGS R + SGG GGS
Sbjct: 606 GGSSGGSIGGRGSSSGGVKSSGGS 629
Score = 38.5 bits (88), Expect = 0.012
Identities = 35/119 (29%), Positives = 39/119 (32%), Gaps = 35/119 (29%)
Query: 181 GGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGG------------------ 222
GG G + S R GGG + GGGGG
Sbjct: 14 GGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRSLVNLGGS 73
Query: 223 ---SLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGG 278
S+ R G R SG F G + GGGG GG G GG G GGGG
Sbjct: 74 KSISISVARGGGRGSG-------FGGGYGGGGFGGGGFGGGGFGGG-------GIGGGG 118
Score = 35.0 bits (79), Expect = 0.13
Identities = 35/111 (31%), Positives = 41/111 (36%), Gaps = 19/111 (17%)
Query: 168 ASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQ 227
+S GG G G GG + V + S+ + GGG GG GGG
Sbjct: 47 SSCGGGGGSFGAGGGFGSRSLVNLGGSK----SISISVARGGGRGSGFGGGYGGGGFG-- 100
Query: 228 RAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGG 278
G G F G GGGG GG G GG + G GGGG
Sbjct: 101 -GGGFGGGG------FGGGGI----GGGGFGGFGSGGGGF--GGGGFGGGG 138
Score = 34.3 bits (77), Expect = 0.23
Identities = 19/42 (45%), Positives = 21/42 (50%), Gaps = 3/42 (7%)
Query: 242 TFSGSWERRHGGGG---GGGGAGKPGGSWERRQAGSGGGGSW 280
T SG R GGGG GG G GGS+ G GG GS+
Sbjct: 511 TISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSY 552
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 46.6 bits (109), Expect = 4e-05
Identities = 27/66 (40%), Positives = 32/66 (48%), Gaps = 3/66 (4%)
Query: 211 AAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERR 270
+ ++R GGGGG +G+ RR T S S RHGGGGGG G GG R
Sbjct: 6 SCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGG---GGFGSRS 62
Query: 271 QAGSGG 276
G GG
Sbjct: 63 LVGLGG 68
Score = 45.1 bits (105), Expect = 1e-04
Identities = 33/81 (40%), Positives = 38/81 (46%), Gaps = 8/81 (9%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGK--- 262
G GG + +R G GGGGS+ G+ GS R + GS GGG G G GK
Sbjct: 540 GSGGRQSGSRGGSGGGGSISGGGYGS-GGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSS 598
Query: 263 ----PGGSWERRQAGSGGGGS 279
GGS GSGGGGS
Sbjct: 599 GGGSRGGSSSGGGYGSGGGGS 619
Score = 37.0 bits (84), Expect = 0.035
Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW 267
G G + +GGG +G R SGS R G GG G GGG+G GS
Sbjct: 520 GSGGRGSSSGGGYSSGSSSYGSGGRQSGS---RGGSGGGGSISGGGYGSGGGSGGRYGSG 576
Query: 268 ERRQAGSGGGGSW 280
+ GS GG +
Sbjct: 577 GGSKGGSISGGGY 589
Score = 37.0 bits (84), Expect = 0.035
Identities = 27/75 (36%), Positives = 31/75 (41%), Gaps = 14/75 (18%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGG-----GGGAGK 262
GGG + + G GG R G+ GS SG +G GGG G G G
Sbjct: 529 GGGYSSGSSSYGSGGRQSGSRGGSGGGGS------ISGGG---YGSGGGSGGRYGSGGGS 579
Query: 263 PGGSWERRQAGSGGG 277
GGS GSGGG
Sbjct: 580 KGGSISGGGYGSGGG 594
Score = 36.6 bits (83), Expect = 0.046
Identities = 27/67 (40%), Positives = 30/67 (44%), Gaps = 5/67 (7%)
Query: 214 ARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGG---GGGAGKPGGSWERR 270
++A GG G G +SGS S R GGGG GGG G GGS R
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGR- 572
Query: 271 QAGSGGG 277
GSGGG
Sbjct: 573 -YGSGGG 578
Score = 36.2 bits (82), Expect = 0.060
Identities = 36/100 (36%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEA-----RAGGGGGGSLE 225
GG G G GG + VG + S+ G GGG A R GG GGGS
Sbjct: 48 GGGGGFGG--GGFGSRSLVGLGGTKSISISV---AGGGGGFGAAGGFGGRGGGFGGGS-- 100
Query: 226 RQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G+ SG F G GG GG GG G PGG
Sbjct: 101 SFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140
Score = 36.2 bits (82), Expect = 0.060
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 211 AAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERR 270
A++A GG GG G+ + G + + GS R+ G GG GG G G
Sbjct: 513 ASKAAFGGSGG-------RGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGS 565
Query: 271 QAGSGG 276
GSGG
Sbjct: 566 GGGSGG 571
Score = 35.8 bits (81), Expect = 0.078
Identities = 32/113 (28%), Positives = 41/113 (36%), Gaps = 17/113 (15%)
Query: 168 ASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWG-GGAAEARAGGGGGGSLER 226
+S G GR G GG+ + G+G GG + R G GGG
Sbjct: 537 SSYGSGGRQSGSRGGSGGGGSISGG-------------GYGSGGGSGGRYGSGGGSKGGS 583
Query: 227 QRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGS 279
G SG + SG R GGG G+G G S + +G G S
Sbjct: 584 ISGGGYGSGGGKHS---SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSS 633
Score = 35.0 bits (79), Expect = 0.13
Identities = 25/73 (34%), Positives = 32/73 (43%), Gaps = 7/73 (9%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G+GGG +R+ G GG+ + A G + F G GG GGG+G GG
Sbjct: 52 GFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGG 111
Query: 266 SWERRQAGSGGGG 278
G GGGG
Sbjct: 112 -------GFGGGG 117
>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
Length = 947
Score = 46.2 bits (108), Expect = 6e-05
Identities = 47/141 (33%), Positives = 57/141 (40%), Gaps = 28/141 (19%)
Query: 159 VDPVPAGVDASPGGA-----GRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAE 213
V PV AG +A+P GR PGPP P + E + +G GGG
Sbjct: 118 VQPV-AGAEAAPAATLAALGGRRPGPPEEPPRE-----LESVPSKLGEPPPLGEGGGGG- 170
Query: 214 ARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG--------GAGKPGG 265
GG GGGS ER+ G R G ++ GG GG G AGK G
Sbjct: 171 GEGGGAGGGSGERE--GGAPQPPPPRGWRGKGVRAQQRGGSGGEGASPSPSSSSAGKTPG 228
Query: 266 SWERRQ------AGSGGGGSW 280
+ R GSGGGGS+
Sbjct: 229 TGSRNSGSGVAGGGSGGGGSY 249
Score = 44.3 bits (103), Expect = 2e-04
Identities = 44/171 (25%), Positives = 57/171 (33%), Gaps = 32/171 (18%)
Query: 160 DPVPAGVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGG 219
+P P G GG G + G GG +R G + GW G A+ GG
Sbjct: 159 EPPPLG---EGGGGGGEGGGAGGGSGEREGGAPQPPPP-------RGWRGKGVRAQQRGG 208
Query: 220 GGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW------------ 267
GG GA S S G+ R G G GGG+G G W
Sbjct: 209 SGGE------GASPSPSSSSAGKTPGTGSRNSGSGVAGGGSGGGGSYWKEGCLQSELIQF 262
Query: 268 ----ERRQAGSGGGGSWERRHPGPNPLDPQDPSPDAYCNLVILAVANRDAA 314
ER A + + G + P A C + +A A+ AA
Sbjct: 263 HLKKERAAAAAAAAQMHAKNGGGSSSRSSPVSGPPAVCETLAVASASPMAA 313
>gi|5803036 heterogeneous nuclear ribonucleoprotein A0 [Homo
sapiens]
Length = 305
Score = 46.2 bits (108), Expect = 6e-05
Identities = 29/75 (38%), Positives = 33/75 (44%), Gaps = 2/75 (2%)
Query: 206 GWGGGAAEARAGGGGGGSL--ERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKP 263
G GGG A GGGGG S G GS+ + Q+ G + GGGGGG G
Sbjct: 225 GGGGGGYNAYGGGGGGSSYGGSDYGNGFGGFGSYSQHQSSYGPMKSGGGGGGGGSSWGGR 284
Query: 264 GGSWERRQAGSGGGG 278
S R GGGG
Sbjct: 285 SNSGPYRGGYGGGGG 299
Score = 39.7 bits (91), Expect = 0.005
Identities = 26/88 (29%), Positives = 36/88 (40%), Gaps = 5/88 (5%)
Query: 206 GWGGGAAEARAGGGG---GGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGK 262
G GGG+ +R G GG GG ++ G + + G + GGGGG
Sbjct: 183 GGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGGGGGSS 242
Query: 263 PGGSWERRQAGSGGGGSWERRHPGPNPL 290
GGS G GG GS+ + P+
Sbjct: 243 YGGS--DYGNGFGGFGSYSQHQSSYGPM 268
Score = 39.3 bits (90), Expect = 0.007
Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 8/77 (10%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG----GAG 261
G GGG + + GG GG R R G R + + +GGGGGGG G G
Sbjct: 182 GGGGGGSRSSRGGRGG----RGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGGYNAYGGG 237
Query: 262 KPGGSWERRQAGSGGGG 278
G S+ G+G GG
Sbjct: 238 GGGSSYGGSDYGNGFGG 254
Score = 38.1 bits (87), Expect = 0.016
Identities = 27/68 (39%), Positives = 30/68 (44%), Gaps = 11/68 (16%)
Query: 216 AGGGGGGS-LERQRAGARASGSWERRQTFS---GSWERRHGGGGGGGGAGKPGGSWERRQ 271
+GGGGGGS R G R G + S G +GG GGGGG G
Sbjct: 181 SGGGGGGSRSSRGGRGGRGRGGGRDQNGLSKGGGGGYNSYGGYGGGGGGG-------YNA 233
Query: 272 AGSGGGGS 279
G GGGGS
Sbjct: 234 YGGGGGGS 241
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 45.8 bits (107), Expect = 8e-05
Identities = 42/131 (32%), Positives = 51/131 (38%), Gaps = 11/131 (8%)
Query: 165 GVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGG-- 222
G S GG G G GG+ + G + + G+GGG+ +GG GGG
Sbjct: 492 GSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHS 551
Query: 223 -SLERQRAGARASGSWERRQTFSGSWER-----RHGGGGGGGG--AGKPGGSWERRQAGS 274
G SG GS R HGGG G GG G GG E +G
Sbjct: 552 GGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611
Query: 275 G-GGGSWERRH 284
G GGGS + H
Sbjct: 612 GYGGGSGKSSH 622
Score = 43.5 bits (101), Expect = 4e-04
Identities = 29/74 (39%), Positives = 33/74 (44%), Gaps = 1/74 (1%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G GG+ + GG GGS +G G R GS+ G GGG GG G GG
Sbjct: 479 GGSGGSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGG-GYGGG 537
Query: 266 SWERRQAGSGGGGS 279
S GSGGG S
Sbjct: 538 SGGGHSGGSGGGHS 551
Score = 43.1 bits (100), Expect = 5e-04
Identities = 33/77 (42%), Positives = 40/77 (51%), Gaps = 17/77 (22%)
Query: 214 ARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG----GAGKPGGSWER 269
+R+GGGGGG L +G S+ R FS S GGGGGGG +G GGS
Sbjct: 12 SRSGGGGGGGLG---SGGSIRSSYSR---FSSS-----GGGGGGGRFSSSSGYGGGS--S 58
Query: 270 RQAGSGGGGSWERRHPG 286
R G GGGGS+ + G
Sbjct: 59 RVCGRGGGGSFGYSYGG 75
Score = 43.1 bits (100), Expect = 5e-04
Identities = 30/77 (38%), Positives = 36/77 (46%), Gaps = 5/77 (6%)
Query: 204 RMGWGGGAAEARAGGG-GGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGK 262
R G GG +GGG GGGS R +G GS+ G +GGG GGG +G
Sbjct: 490 RGGSGGSYGGGGSGGGYGGGSGSRGGSG----GSYGGGSGSGGGSGGGYGGGSGGGHSGG 545
Query: 263 PGGSWERRQAGSGGGGS 279
GG G+ GGGS
Sbjct: 546 SGGGHSGGSGGNYGGGS 562
Score = 40.0 bits (92), Expect = 0.004
Identities = 35/106 (33%), Positives = 43/106 (40%), Gaps = 8/106 (7%)
Query: 165 GVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSL 224
G S GG+G G GG G + H+ S G G G+ GG GGGS
Sbjct: 522 GGSGSGGGSG---GGYGGGSGGGHSGGSGGGHSGGS-GGNYGGGSGSGGGSGGGYGGGSG 577
Query: 225 ERQRAGARASGS----WERRQTFSGSWERRHGGGGGGGGAGKPGGS 266
R +G G E ++ G E GGG GGG+GK S
Sbjct: 578 SRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKSSHS 623
Score = 39.7 bits (91), Expect = 0.005
Identities = 29/75 (38%), Positives = 36/75 (48%), Gaps = 5/75 (6%)
Query: 206 GWGGGAAEARAGGG-GGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGG-GAGKP 263
G GGG + + GGG GGGS + G + G + F G + GGG GGG G+G
Sbjct: 76 GSGGGFSASSLGGGFGGGS---RGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFG 132
Query: 264 GGSWERRQAGSGGGG 278
G AG G GG
Sbjct: 133 GFGGFGGGAGGGDGG 147
Score = 39.3 bits (90), Expect = 0.007
Identities = 26/69 (37%), Positives = 29/69 (42%), Gaps = 9/69 (13%)
Query: 210 GAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWER 269
GA + GG GG R SG GS+ GGG GGG+G GGS
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGGSG---------GSYGGGGSGGGYGGGSGSRGGSGGS 519
Query: 270 RQAGSGGGG 278
GSG GG
Sbjct: 520 YGGGSGSGG 528
Score = 38.9 bits (89), Expect = 0.009
Identities = 25/73 (34%), Positives = 28/73 (38%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW 267
GGG+ GGG GG G G SG GG GGG G G GG
Sbjct: 65 GGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFG 124
Query: 268 ERRQAGSGGGGSW 280
+G GG G +
Sbjct: 125 GGYGSGFGGFGGF 137
Score = 35.4 bits (80), Expect = 0.10
Identities = 26/73 (35%), Positives = 31/73 (42%), Gaps = 3/73 (4%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGG-GGGGAGKPG 264
G+GGG++ G GGGGS G + G + G G GG GGG G
Sbjct: 52 GYGGGSSRV-CGRGGGGSFGYSYGGG-SGGGFSASSLGGGFGGGSRGFGGASGGGYSSSG 109
Query: 265 GSWERRQAGSGGG 277
G GSGGG
Sbjct: 110 GFGGGFGGGSGGG 122
Score = 35.0 bits (79), Expect = 0.13
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 1/73 (1%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G GGG + +G GGG S R G + G + G + GGG GGG+ GG
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFG-YSYGGGSGGGFSASSLGGGFGGGSRGFGG 99
Query: 266 SWERRQAGSGGGG 278
+ + SGG G
Sbjct: 100 ASGGGYSSSGGFG 112
Score = 33.1 bits (74), Expect = 0.50
Identities = 20/43 (46%), Positives = 22/43 (51%)
Query: 240 RQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWER 282
RQ S R GGGGGG G+G S R + SGGGG R
Sbjct: 4 RQFSSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGR 46
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 9/82 (10%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGG---GGGAGKPG 264
G G GG GGS R G + GS+ + G +GGG G G G G
Sbjct: 469 GAGKIGLGGRGGSGGSYGRGSRGG-SGGSYGGGGSGGG-----YGGGSGSRGGSGGSYGG 522
Query: 265 GSWERRQAGSGGGGSWERRHPG 286
GS +G G GG H G
Sbjct: 523 GSGSGGGSGGGYGGGSGGGHSG 544
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 45.8 bits (107), Expect = 8e-05
Identities = 34/101 (33%), Positives = 40/101 (39%), Gaps = 14/101 (13%)
Query: 218 GGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
GGGG E +RAGA S + GGGG G G GGS R A GGG
Sbjct: 187 GGGGSGGESRRAGAADSAPYP-------------GGGGNGASGGGSGGSKRRLDASEGGG 233
Query: 278 GSWERRHPGPNPLDPQD-PSPDAYCNLVILAVANRDAAEES 317
G+ L D P + L++ V D AE S
Sbjct: 234 GTNPGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENS 274
Score = 32.3 bits (72), Expect = 0.86
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 175 RDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARAS 234
++PG G E RR G A+ S + G G GA+ GGG GGS R A
Sbjct: 184 QEPGGGGSGGESRRAGAAD------SAPYPGGGGNGAS----GGGSGGSKRRLDASEGGG 233
Query: 235 GS 236
G+
Sbjct: 234 GT 235
>gi|21536320 heterogeneous nuclear ribonucleoprotein U-like 1
isoform d [Homo sapiens]
Length = 756
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/139 (30%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 174 GRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARA 233
GR GPP PEKR D R GGG R GGGG E +
Sbjct: 498 GRKAGPP---PEKR-------------FDNR---GGGGFRGRGGGGGFQRYENRGPPGGN 538
Query: 234 SGSWERRQTFSGSWERRHGG---GGGGGGAGKPGGSWERRQAGSGGGGSWER-------- 282
G ++ R SG GG GGGG + G+ R S GS+ R
Sbjct: 539 RGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPP 598
Query: 283 -RHPGPNPLDPQDPSPDAY 300
+ P P P Q P P +Y
Sbjct: 599 QQPPPPQPPPQQPPPPPSY 617
>gi|21536326 heterogeneous nuclear ribonucleoprotein U-like 1
isoform a [Homo sapiens]
Length = 856
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/139 (30%), Positives = 51/139 (36%), Gaps = 31/139 (22%)
Query: 174 GRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARA 233
GR GPP PEKR D R GGG R GGGG E +
Sbjct: 598 GRKAGPP---PEKR-------------FDNR---GGGGFRGRGGGGGFQRYENRGPPGGN 638
Query: 234 SGSWERRQTFSGSWERRHGG---GGGGGGAGKPGGSWERRQAGSGGGGSWER-------- 282
G ++ R SG GG GGGG + G+ R S GS+ R
Sbjct: 639 RGGFQNRGGGSGGGGNYRGGFNRSGGGGYSQNRWGNNNRDNNNSNNRGSYNRAPQQQPPP 698
Query: 283 -RHPGPNPLDPQDPSPDAY 300
+ P P P Q P P +Y
Sbjct: 699 QQPPPPQPPPQQPPPPPSY 717
>gi|126090909 engrailed homeobox 1 [Homo sapiens]
Length = 392
Score = 44.7 bits (104), Expect = 2e-04
Identities = 33/98 (33%), Positives = 41/98 (41%), Gaps = 6/98 (6%)
Query: 167 DASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLER 226
D AGRDP P G R G A +C+ D G G+ A AG G +
Sbjct: 145 DRGQTAAGRDPVHPLGT---RAPGAAS---LLCAPDANCGPPDGSQPAAAGAGASKAGNP 198
Query: 227 QRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPG 264
A A A+ + + + GGGG GGGAG PG
Sbjct: 199 AAAAAAAAAAVAAAAAAAAAKPSDTGGGGSGGGAGSPG 236
Score = 29.3 bits (64), Expect = 7.3
Identities = 15/25 (60%), Positives = 17/25 (68%), Gaps = 1/25 (4%)
Query: 211 AAEARAGGGGGGSLERQRAGARASG 235
AA AR G GGGG +ER R G A+G
Sbjct: 129 AAAARGGAGGGGRVERDR-GQTAAG 152
>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
sapiens]
Length = 940
Score = 44.7 bits (104), Expect = 2e-04
Identities = 44/131 (33%), Positives = 47/131 (35%), Gaps = 20/131 (15%)
Query: 171 GGAGRDP--GPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAG--GGGGGSLER 226
GG G P GP GG +G + MG G E G GGGGG
Sbjct: 747 GGGGHRPHEGPGGG------MGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPH 800
Query: 227 QRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPG 286
+ G SG GS R H G GGG GAG G GS GG R H G
Sbjct: 801 EGPGGGISG---------GSGHRPHEGPGGGMGAGG-GHRPHEGPGGSMGGSGGHRPHEG 850
Query: 287 PNPLDPQDPSP 297
P P P
Sbjct: 851 PGHGGPHGHRP 861
Score = 41.6 bits (96), Expect = 0.001
Identities = 46/148 (31%), Positives = 50/148 (33%), Gaps = 25/148 (16%)
Query: 158 GVDPVPAGVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAG 217
G P P GG G + PP P + G R + R G GGG G
Sbjct: 695 GPGPGPGPYHRGRGGRGGNEPPPPPPPFR---GARGGRSGGGPPNGRGGPGGG----MVG 747
Query: 218 GGGGGSLERQRAGARASGSWERRQTFSGSWERRH----------GGGGG-----GGGAGK 262
GGG E G S + G H GGGGG G G G
Sbjct: 748 GGGHRPHEGPGGGMGNSSGHRPHEGPGGGMGSGHRPHEGPGGSMGGGGGHRPHEGPGGGI 807
Query: 263 PGGSWERRQAGSGGG---GSWERRHPGP 287
GGS R G GGG G R H GP
Sbjct: 808 SGGSGHRPHEGPGGGMGAGGGHRPHEGP 835
Score = 39.3 bits (90), Expect = 0.007
Identities = 54/187 (28%), Positives = 61/187 (32%), Gaps = 41/187 (21%)
Query: 133 PTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDAS------------PGGAGRDPGP- 179
P+ E+ D +LV LG P+ G PG G PGP
Sbjct: 596 PSEELLKQPDYSDKIKQMLVPHGLLGPGPIANGFPPGGPGGPKGMQHFPPGPGGPMPGPH 655
Query: 180 --PGGAPEKRRVGTAERRHTICSLDWRMG---WGGGAAEARAG------GGGGGSLERQR 228
PGG R +G R G W G R G G G G R R
Sbjct: 656 GGPGGPVGPRLLGPPPPP--------RGGDPFWDGPGDPMRGGPMRGGPGPGPGPYHRGR 707
Query: 229 AGARASGSWERRQTFSGSWERRHGGG-----GGGGGAGKPGGSWERRQAGSGGG---GSW 280
G + F G+ R GGG GG GG GG R G GGG S
Sbjct: 708 GGRGGNEPPPPPPPFRGARGGRSGGGPPNGRGGPGGG-MVGGGGHRPHEGPGGGMGNSSG 766
Query: 281 ERRHPGP 287
R H GP
Sbjct: 767 HRPHEGP 773
>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/122 (33%), Positives = 49/122 (40%), Gaps = 22/122 (18%)
Query: 152 VLKTGLGVDPVPAGVDA---SPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWG 208
V G + +PAGV G R GG E VG ++ IC L ++G
Sbjct: 515 VAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVG---QQLAICMLHGQLGTA 571
Query: 209 ---------GGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGG 259
GGA RAG + R+ R G W RR RRHGGGGGGGG
Sbjct: 572 PHAHVPTVLGGALGGRAGLVAAPA-RRECPARRRGGCWPRRP------RRRHGGGGGGGG 624
Query: 260 AG 261
G
Sbjct: 625 PG 626
Score = 30.8 bits (68), Expect = 2.5
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 4/123 (3%)
Query: 165 GVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSL 224
G +A G R G G P V R+ + + R+G AA R G G GG
Sbjct: 819 GHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGAGGGG 878
Query: 225 ERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRH 284
R R G + +R + ++RH A + + + R G G+ RH
Sbjct: 879 RRVRHGHGHGAAVLQR---APCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRH 935
Query: 285 -PG 286
PG
Sbjct: 936 RPG 938
Score = 30.8 bits (68), Expect = 2.5
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 5/115 (4%)
Query: 168 ASPGGAGRDP--GPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARA--GGGGGGS 223
A GG GR G GA +R ++RH + G AA+ RA G G
Sbjct: 872 AGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAP 931
Query: 224 LERQRAGARASGSWERRQ-TFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
R R GAR S R +G G G G+ G+ QA GG
Sbjct: 932 SHRHRPGARGRRSRRRAAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGG 986
>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1297
Score = 44.7 bits (104), Expect = 2e-04
Identities = 41/122 (33%), Positives = 49/122 (40%), Gaps = 22/122 (18%)
Query: 152 VLKTGLGVDPVPAGVDA---SPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWG 208
V G + +PAGV G R GG E VG ++ IC L ++G
Sbjct: 515 VAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHVEVVPVG---QQLAICMLHGQLGTA 571
Query: 209 ---------GGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGG 259
GGA RAG + R+ R G W RR RRHGGGGGGGG
Sbjct: 572 PHAHVPTVLGGALGGRAGLVAAPA-RRECPARRRGGCWPRRP------RRRHGGGGGGGG 624
Query: 260 AG 261
G
Sbjct: 625 PG 626
Score = 30.8 bits (68), Expect = 2.5
Identities = 32/123 (26%), Positives = 46/123 (37%), Gaps = 4/123 (3%)
Query: 165 GVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSL 224
G +A G R G G P V R+ + + R+G AA R G G GG
Sbjct: 819 GHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGAGGGG 878
Query: 225 ERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRH 284
R R G + +R + ++RH A + + + R G G+ RH
Sbjct: 879 RRVRHGHGHGAAVLQR---APCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRH 935
Query: 285 -PG 286
PG
Sbjct: 936 RPG 938
Score = 30.8 bits (68), Expect = 2.5
Identities = 34/115 (29%), Positives = 42/115 (36%), Gaps = 5/115 (4%)
Query: 168 ASPGGAGRDP--GPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARA--GGGGGGS 223
A GG GR G GA +R ++RH + G AA+ RA G G
Sbjct: 872 AGAGGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAP 931
Query: 224 LERQRAGARASGSWERRQ-TFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
R R GAR S R +G G G G+ G+ QA GG
Sbjct: 932 SHRHRPGARGRRSRRRAAVALAGGAHPARAALGRRRGGGQAVGARAAHQARLAGG 986
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 44.3 bits (103), Expect = 2e-04
Identities = 36/111 (32%), Positives = 41/111 (36%), Gaps = 10/111 (9%)
Query: 167 DASPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLER 226
+ S GG GR G GG G G GGG + GG GGGS
Sbjct: 456 EGSSGGGGRGGGSFGGGYGGGSSGGGSSGG---------GHGGGHGGSSGGGYGGGSSGG 506
Query: 227 QRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
+G G GS +GGG GGG G GG + SGGG
Sbjct: 507 GSSGGGYGGG-SSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGG 556
Score = 39.3 bits (90), Expect = 0.007
Identities = 28/80 (35%), Positives = 35/80 (43%), Gaps = 12/80 (15%)
Query: 206 GWGGGAAEARAGGGG-GGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPG 264
G+GGG++ + GGG GG G +SG + G GGGG GGG+ G
Sbjct: 498 GYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGY-------GGGSSGGGGGGYGGGSSGGG 550
Query: 265 GSWERRQAGSGGGGSWERRH 284
S G GGGS H
Sbjct: 551 SS----SGGGYGGGSSSGGH 566
Score = 38.9 bits (89), Expect = 0.009
Identities = 29/76 (38%), Positives = 32/76 (42%), Gaps = 7/76 (9%)
Query: 213 EARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGG-GGAGKPGGSWERRQ 271
E GGGG R G G + + GS HGGG GG G G GGS
Sbjct: 454 EGEGSSGGGG-----RGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGS 508
Query: 272 AGSG-GGGSWERRHPG 286
+G G GGGS H G
Sbjct: 509 SGGGYGGGSSSGGHGG 524
Score = 38.5 bits (88), Expect = 0.012
Identities = 29/84 (34%), Positives = 36/84 (42%), Gaps = 13/84 (15%)
Query: 208 GGGAAEARAGGGGGGSLER-----------QRAGARASGSWERRQTFSGSWERRHGGGGG 256
GGG GGGGG S R +G + GS+ R + G + GG GG
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76
Query: 257 GGGAGKPGGSWERRQAGSGGGGSW 280
GG G GGS+ S GGS+
Sbjct: 77 LGGFG--GGSFRGSYGSSSFGGSY 98
Score = 33.1 bits (74), Expect = 0.50
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 8/76 (10%)
Query: 208 GGGAAEARAGGG--GGGSLERQRAGARASGSWE---RRQTFSGSWERRHGGGGGGGGAGK 262
GG + +GGG GG S G GS+ +F GS+ GGG GGG+
Sbjct: 54 GGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS-F 112
Query: 263 PGGSWERRQAGSGGGG 278
GGS+ G GGGG
Sbjct: 113 GGGSF--GGGGFGGGG 126
Score = 32.7 bits (73), Expect = 0.66
Identities = 18/32 (56%), Positives = 18/32 (56%), Gaps = 3/32 (9%)
Query: 250 RHGGGGGGGGAGKPGGSWERR---QAGSGGGG 278
R GGGGGGGG G GG R GS GGG
Sbjct: 15 RSGGGGGGGGCGGGGGVSSLRISSSKGSLGGG 46
Score = 32.3 bits (72), Expect = 0.86
Identities = 19/46 (41%), Positives = 21/46 (45%), Gaps = 3/46 (6%)
Query: 241 QTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPG 286
QT+ E GGGG G G GG + GS GGGS H G
Sbjct: 447 QTYRSLLEGEGSSGGGGRGGGSFGGGY---GGGSSGGGSSGGGHGG 489
Score = 32.0 bits (71), Expect = 1.1
Identities = 24/75 (32%), Positives = 30/75 (40%), Gaps = 12/75 (16%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G+GG GG GGGS + GS + GS+ GGG GG GG
Sbjct: 73 GYGG------LGGFGGGSFRGSYGSSSFGGS------YGGSFGGGSFGGGSFGGGSFGGG 120
Query: 266 SWERRQAGSGGGGSW 280
+ G G GG +
Sbjct: 121 GFGGGGFGGGFGGGF 135
Score = 30.8 bits (68), Expect = 2.5
Identities = 31/117 (26%), Positives = 41/117 (35%), Gaps = 37/117 (31%)
Query: 169 SPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQR 228
S GG G GG+ G++ G+GGG++ GGGGGG
Sbjct: 503 SSGGGSSGGGYGGGSSSGGHGGSSSG-----------GYGGGSS----GGGGGG------ 541
Query: 229 AGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHP 285
G +SG GG GGG G S + + SG G + P
Sbjct: 542 YGGGSSG----------------GGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582
>gi|119395716 forkhead box C1 [Homo sapiens]
Length = 553
Score = 43.5 bits (101), Expect = 4e-04
Identities = 40/124 (32%), Positives = 47/124 (37%), Gaps = 28/124 (22%)
Query: 169 SPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLD----WRMGWGGGAAEARAGGGGGGSL 224
S GG G G GGA G A H C+L + G GG + GG GG ++
Sbjct: 373 SSGGGGGGAGAAGGA------GGAGTYH--CNLQAMSLYAAGERGGHLQGAPGGAGGSAV 424
Query: 225 ERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG-----------SWERRQAG 273
+ T S S HGGGGGGGG G+ G SW QAG
Sbjct: 425 DDPLPDYSLPPV-----TSSSSSSLSHGGGGGGGGGGQEAGHHPAAHQGRLTSWYLNQAG 479
Query: 274 SGGG 277
G
Sbjct: 480 GDLG 483
>gi|9966841 cell death regulator aven [Homo sapiens]
Length = 362
Score = 43.1 bits (100), Expect = 5e-04
Identities = 36/97 (37%), Positives = 39/97 (40%), Gaps = 26/97 (26%)
Query: 171 GGAGRDPGP--PGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQR 228
GG GR PG PGG R G A AA AR GGGGGG
Sbjct: 9 GGRGRRPGRGRPGGDRHSERPGAA------------------AAVARGGGGGGGG---DG 47
Query: 229 AGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G R G R + F G+ R GGG G +PGG
Sbjct: 48 GGRRGRG---RGRGFRGARGGRGGGGAPRGSRREPGG 81
Score = 38.5 bits (88), Expect = 0.012
Identities = 30/87 (34%), Positives = 36/87 (41%), Gaps = 18/87 (20%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G GG G GG +R GA A+ + R GGGGGG G G+ G
Sbjct: 6 GARGGRGRRPGRGRPGGDRHSERPGAAAAVA------------RGGGGGGGGDGGGRRGR 53
Query: 266 SWER----RQAGSGGGGS--WERRHPG 286
R + G GGGG+ RR PG
Sbjct: 54 GRGRGFRGARGGRGGGGAPRGSRREPG 80
>gi|84570137 homeobox B3 [Homo sapiens]
Length = 431
Score = 43.1 bits (100), Expect = 5e-04
Identities = 41/152 (26%), Positives = 61/152 (40%), Gaps = 31/152 (20%)
Query: 139 AASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGGAPEKRRVGTAERRHTI 198
AA + + L+ ++ GL +P+ A PG PP AP ++
Sbjct: 60 AAPHAKSKELNGSCMRPGLAPEPL----SAPPGSP-----PPSAAPTSATSNSSN----- 105
Query: 199 CSLDWRMGWGGGAAEA---RAGGGGGGSLERQR-AGARASGSWERRQTFSGSWERRHGGG 254
GGG +++ + G G +L +Q + S + + S GGG
Sbjct: 106 ---------GGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQTSKLKNNSPGTAEGCGGG 156
Query: 255 GGGGGAGKPGGSWERRQAGSGGGGSWERRHPG 286
GGGGG G GGS G GGGG ++ PG
Sbjct: 157 GGGGGGGGSGGS----GGGGGGGGGGDKSPPG 184
Score = 37.4 bits (85), Expect = 0.027
Identities = 37/119 (31%), Positives = 42/119 (35%), Gaps = 30/119 (25%)
Query: 161 PVPAGVDASPGGAGRDPGPPGGAPEKRRVGTA-------ERRHTICSLDWRMGWGGGAAE 213
P A ++S GG GPP P T E R T G AE
Sbjct: 96 PTSATSNSSNGGGPSKSGPPKCGPGTNSTLTKQIFPWMKESRQT----SKLKNNSPGTAE 151
Query: 214 ARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQA 272
GGGGGG G+ SG GGGGGGGG P GS ++A
Sbjct: 152 GCGGGGGGGG----GGGSGGSGG---------------GGGGGGGGDKSPPGSAASKRA 191
>gi|122937261 coiled-coil domain containing 85A [Homo sapiens]
Length = 553
Score = 43.1 bits (100), Expect = 5e-04
Identities = 41/118 (34%), Positives = 53/118 (44%), Gaps = 11/118 (9%)
Query: 180 PGGAPEK--RRV--GTAE--RRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARA 233
PG +PE + V G+ E ++H S GG+ E GGSLE AR
Sbjct: 298 PGSSPETLPKHVLSGSPEHFQKHRSGSSPEHARHSGGSPEHLQKHALGGSLEHLPR-ARG 356
Query: 234 SGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWE---RRQAGSGGGGSWERRHPGPN 288
+ +Q + GS + +HGGG GG G G GGS E RRQA G + G N
Sbjct: 357 TSPEHLKQHYGGSPDHKHGGGSGGSG-GSGGGSREGTLRRQAQEDGSPHHRNVYSGMN 413
>gi|29029632 anaplastic lymphoma kinase [Homo sapiens]
Length = 1620
Score = 42.7 bits (99), Expect = 6e-04
Identities = 51/178 (28%), Positives = 66/178 (37%), Gaps = 34/178 (19%)
Query: 126 EELILRIPTHEIAAASYLQDDALHLLVLKTGLGVDPVPAGVDASPGGAGRDPGPPGGAPE 185
EE+ + HE A A ++ +K G+ PVP + A GG GR G
Sbjct: 803 EEIRVNRSVHEWAGGGGGGGGATYVFKMKDGV---PVPLIIAA--GGGGRAYGAKTDTFH 857
Query: 186 KRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGAR----ASGSWERRQ 241
R+ E ++ L+ G GG GGG + AG A+G Q
Sbjct: 858 PERL---ENNSSVLGLNGNSGAAGG------GGGWNDNTSLLWAGKSLQEGATGGHSCPQ 908
Query: 242 TFSG-SWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSWERRHPGPNPLDPQDPSPD 298
WE R G GGGGGG +G GGGG + G N DP D
Sbjct: 909 AMKKWGWETRGGFGGGGGGC----------SSGGGGGG-----YIGGNAASNNDPEMD 951
>gi|239750846 PREDICTED: hypothetical protein [Homo sapiens]
Length = 463
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSG--SWERRHGGGG---GGGGAG 261
WGGG + G R R G + GS R + G + ER GGGG GG
Sbjct: 6 WGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
Query: 262 KPGGSWERRQAGSGGGGSWERRHPG 286
G RR GG G W+RR G
Sbjct: 66 GRGAERGRRVREQGGDGRWQRRQRG 90
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/108 (36%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 172 GAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLE----RQ 227
G GR PG A E T + S+ GGG A R GGGG +L R
Sbjct: 7 GGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRG 66
Query: 228 RAGARASGSWERRQTFSGSWERR---HGGGGGGGGAGKPGGSWERRQA 272
R R G R Q G W+RR HGG G G G G RR A
Sbjct: 67 RGAER--GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVA 112
Score = 35.0 bits (79), Expect = 0.13
Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 21/139 (15%)
Query: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSL-DWRMGWGGGAAEARAGGGGGGSLERQRA 229
G G + GG RRV +RH + ++ R G GGG + GG++ A
Sbjct: 93 GRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDH-----AGGAIHVWPA 147
Query: 230 GA-RASGSWERRQTFSGSWERRHGGGG--------------GGGGAGKPGGSWERRQAGS 274
GA RA+ + GS R HGG G G G + G Q
Sbjct: 148 GAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVG 207
Query: 275 GGGGSWERRHPGPNPLDPQ 293
GGG W+ R G +PQ
Sbjct: 208 GGGHLWQVRARGRQRAEPQ 226
>gi|239745208 PREDICTED: hypothetical protein XP_002343389 [Homo
sapiens]
Length = 463
Score = 42.7 bits (99), Expect = 6e-04
Identities = 30/85 (35%), Positives = 35/85 (41%), Gaps = 5/85 (5%)
Query: 207 WGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSG--SWERRHGGGG---GGGGAG 261
WGGG + G R R G + GS R + G + ER GGGG GG
Sbjct: 6 WGGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLR 65
Query: 262 KPGGSWERRQAGSGGGGSWERRHPG 286
G RR GG G W+RR G
Sbjct: 66 GRGAERGRRVREQGGDGRWQRRQRG 90
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/108 (36%), Positives = 43/108 (39%), Gaps = 9/108 (8%)
Query: 172 GAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLE----RQ 227
G GR PG A E T + S+ GGG A R GGGG +L R
Sbjct: 7 GGGRQDWEPGKASEVVGRRTRGGVGSCGSVHRHRVQGGGRAGERFAGGGGAALAGGCLRG 66
Query: 228 RAGARASGSWERRQTFSGSWERR---HGGGGGGGGAGKPGGSWERRQA 272
R R G R Q G W+RR HGG G G G G RR A
Sbjct: 67 RGAER--GRRVREQGGDGRWQRRQRGHGGRRGLNGHGDGGQRLARRVA 112
Score = 35.0 bits (79), Expect = 0.13
Identities = 40/139 (28%), Positives = 53/139 (38%), Gaps = 21/139 (15%)
Query: 171 GGAGRDPGPPGGAPEKRRVGTAERRHTICSL-DWRMGWGGGAAEARAGGGGGGSLERQRA 229
G G + GG RRV +RH + ++ R G GGG + GG++ A
Sbjct: 93 GRRGLNGHGDGGQRLARRVAQRLQRHAVGAVVATRHGDGGGRVDH-----AGGAIHVWPA 147
Query: 230 GA-RASGSWERRQTFSGSWERRHGGGG--------------GGGGAGKPGGSWERRQAGS 274
GA RA+ + GS R HGG G G G + G Q
Sbjct: 148 GAQRAAHGSQLVGERVGSGHRLHGGEGQPPRHLVFPRDDVLDGEGVLEARGLRHAAQVVG 207
Query: 275 GGGGSWERRHPGPNPLDPQ 293
GGG W+ R G +PQ
Sbjct: 208 GGGHLWQVRARGRQRAEPQ 226
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 42.7 bits (99), Expect = 6e-04
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 13/62 (20%)
Query: 218 GGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
GGGG E +RAGA S + GGGG G G GGS R A GGG
Sbjct: 187 GGGGSGGESRRAGAADSAPYP-------------GGGGNGASGGGSGGSKRRLDASEGGG 233
Query: 278 GS 279
G+
Sbjct: 234 GT 235
Score = 32.3 bits (72), Expect = 0.86
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 175 RDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARAS 234
++PG G E RR G A+ S + G G GA+ GGG GGS R A
Sbjct: 184 QEPGGGGSGGESRRAGAAD------SAPYPGGGGNGAS----GGGSGGSKRRLDASEGGG 233
Query: 235 GS 236
G+
Sbjct: 234 GT 235
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 42.7 bits (99), Expect = 6e-04
Identities = 25/62 (40%), Positives = 28/62 (45%), Gaps = 13/62 (20%)
Query: 218 GGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
GGGG E +RAGA S + GGGG G G GGS R A GGG
Sbjct: 187 GGGGSGGESRRAGAADSAPYP-------------GGGGNGASGGGSGGSKRRLDASEGGG 233
Query: 278 GS 279
G+
Sbjct: 234 GT 235
Score = 32.3 bits (72), Expect = 0.86
Identities = 22/62 (35%), Positives = 28/62 (45%), Gaps = 10/62 (16%)
Query: 175 RDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGGGGGGSLERQRAGARAS 234
++PG G E RR G A+ S + G G GA+ GGG GGS R A
Sbjct: 184 QEPGGGGSGGESRRAGAAD------SAPYPGGGGNGAS----GGGSGGSKRRLDASEGGG 233
Query: 235 GS 236
G+
Sbjct: 234 GT 235
>gi|42544153 leukocyte receptor tyrosine kinase isoform 1 precursor
[Homo sapiens]
Length = 864
Score = 42.7 bits (99), Expect = 6e-04
Identities = 40/127 (31%), Positives = 47/127 (37%), Gaps = 30/127 (23%)
Query: 180 PGGAPEKRRVGTAERR--HTICSLDWRMGWGGGAAEARAGGGGGGS--LERQRAG----- 230
PGG+PE + V E R ++D G G A GGGGGG+ + R RAG
Sbjct: 169 PGGSPESQLVCLGESRAVEEHAAMDGSEGVPGSRRWAGGGGGGGGATYVFRVRAGELEPL 228
Query: 231 -ARASGSWE---------RRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGGGSW 280
A G R Q E R G GG G +GGGG W
Sbjct: 229 LVAAGGGGRAYLRPRDRGRTQASPEKLENRSEAPGSGGRGG-----------AAGGGGGW 277
Query: 281 ERRHPGP 287
R P P
Sbjct: 278 TSRAPSP 284
Score = 34.3 bits (77), Expect = 0.23
Identities = 40/124 (32%), Positives = 43/124 (34%), Gaps = 28/124 (22%)
Query: 163 PAGVDASPGGAG----RDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWGGGAAEARAGG 218
P V A GG RD G +PEK E R G GG A GG
Sbjct: 227 PLLVAAGGGGRAYLRPRDRGRTQASPEK-----LENRSEA------PGSGGRGGAAGGGG 275
Query: 219 GGGGSLERQRAGARASGSWERRQTFSGSWE----RRHGGGGGGGGAGKPGGSWERRQAGS 274
G +AG E Q S +W GG GGGGGA GG
Sbjct: 276 GWTSRAPSPQAGRSLQEGAEGGQGCSEAWATLGWAAAGGFGGGGGACTAGG--------- 326
Query: 275 GGGG 278
GGGG
Sbjct: 327 GGGG 330
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 42.4 bits (98), Expect = 8e-04
Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 6/72 (8%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSW 267
GGG +GGGGGG + G+ S + SG GGGG G GG
Sbjct: 61 GGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGG-- 118
Query: 268 ERRQAGSGGGGS 279
GS GGGS
Sbjct: 119 ----GGSSGGGS 126
Score = 42.0 bits (97), Expect = 0.001
Identities = 27/74 (36%), Positives = 28/74 (37%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
G GGG GGG GG G G + GS GGG GG G G G
Sbjct: 28 GSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGS 87
Query: 266 SWERRQAGSGGGGS 279
GS GGGS
Sbjct: 88 VKYSGGGGSSGGGS 101
Score = 40.4 bits (93), Expect = 0.003
Identities = 27/79 (34%), Positives = 33/79 (41%), Gaps = 5/79 (6%)
Query: 206 GWGGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGG-----GGGGGGA 260
G GGG++ GGG GG + SG SG + GG GGGG +
Sbjct: 63 GCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSS 122
Query: 261 GKPGGSWERRQAGSGGGGS 279
G G + GS GGGS
Sbjct: 123 GGGSGCFSSGGGGSSGGGS 141
Score = 38.1 bits (87), Expect = 0.016
Identities = 29/77 (37%), Positives = 35/77 (45%), Gaps = 9/77 (11%)
Query: 206 GWGGGAAEARAGGG---GGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGK 262
G GGG+ +GGG GGGS +G SG +Q S + GGG G G
Sbjct: 180 GGGGGSVCGYSGGGSGCGGGS-----SGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGG 234
Query: 263 PGGSWERRQAGSGGGGS 279
GGS +G GGG S
Sbjct: 235 SGGS-GCFSSGGGGGSS 250
Score = 37.7 bits (86), Expect = 0.020
Identities = 29/81 (35%), Positives = 35/81 (43%), Gaps = 11/81 (13%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGG--GGGGGAGKPGG 265
GGG +GGGG G +G +SGS +SG GGG GGG G G GG
Sbjct: 21 GGGGGGGGSGGGGCGFFGGGGSGGGSSGSG---CGYSG------GGGYSGGGCGGGSSGG 71
Query: 266 SWERRQAGSGGGGSWERRHPG 286
G GGG ++ G
Sbjct: 72 GGGGGIGGCGGGSGGSVKYSG 92
Score = 37.0 bits (84), Expect = 0.035
Identities = 38/115 (33%), Positives = 45/115 (39%), Gaps = 16/115 (13%)
Query: 169 SPGGAGRDPGPPGGAPEKRRVGTAERRHTICSLDWRMGWG--GGAAEARAG----GGGGG 222
S GG+G G GG+ V + + T C+ G G GG +G GGGGG
Sbjct: 190 SGGGSGCGGGSSGGSGSGY-VSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGG 248
Query: 223 SLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGGSWERRQAGSGGG 277
S G +SG G G GGGGG GGS GSG G
Sbjct: 249 S---SGCGGGSSGIGSGCIISGGGSVCGGGSSGGGGGGSSVGGS------GSGKG 294
Score = 35.4 bits (80), Expect = 0.10
Identities = 30/86 (34%), Positives = 34/86 (39%), Gaps = 23/86 (26%)
Query: 208 GGGAAEARAGGGGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAG--KPGG 265
GGG+ +GGGG G G+ GS FS GGG GGG+G GG
Sbjct: 98 GGGSGCFSSGGGGSGCFSSGGGGSSGGGS----GCFSSG-----GGGSSGGGSGCFSSGG 148
Query: 266 SWERRQA------------GSGGGGS 279
QA GS GGGS
Sbjct: 149 GGFSGQAVQCQSYGGVSSGGSSGGGS 174
Score = 34.7 bits (78), Expect = 0.17
Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 208 GGGAAEARAGGGG--GGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGGGGAGKPGG 265
GGG+ +GGGG G +++ Q G +SG + G GGGGG G GG
Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGG-----SSGGGSGCFSSGGGGGSVCGYSGG 192
Query: 266 SWERRQAGSGGGGS 279
SGG GS
Sbjct: 193 GSGCGGGSSGGSGS 206
Score = 34.3 bits (77), Expect = 0.23
Identities = 27/75 (36%), Positives = 28/75 (37%), Gaps = 12/75 (16%)
Query: 217 GGGGGGSLERQRAGARASGSWERRQTFSGSWERRHG------------GGGGGGGAGKPG 264
GGGGGG G G + SG G GGGGGGG G G
Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCG 81
Query: 265 GSWERRQAGSGGGGS 279
G SGGGGS
Sbjct: 82 GGSGGSVKYSGGGGS 96
Score = 33.5 bits (75), Expect = 0.39
Identities = 26/79 (32%), Positives = 32/79 (40%), Gaps = 5/79 (6%)
Query: 206 GWGGGAAEARAGG-GGGGSLERQRAGARASGSWERRQTFSGSWERRHGGGGGG----GGA 260
G G G + GG GGGS G SG + Q++ G GGG G GG
Sbjct: 123 GGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGG 182
Query: 261 GKPGGSWERRQAGSGGGGS 279
G + +G GGG S
Sbjct: 183 GGSVCGYSGGGSGCGGGSS 201
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.135 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,843,444
Number of Sequences: 37866
Number of extensions: 1319202
Number of successful extensions: 18063
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 256
Number of HSP's successfully gapped in prelim test: 503
Number of HSP's that attempted gapping in prelim test: 9148
Number of HSP's gapped (non-prelim): 4580
length of query: 433
length of database: 18,247,518
effective HSP length: 105
effective length of query: 328
effective length of database: 14,271,588
effective search space: 4681080864
effective search space used: 4681080864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.