Guide to the Human Genome
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Name: ALK Sequence: fasta or formatted (1620aa) NCBI GI: 29029632
Description:

anaplastic lymphoma kinase

Referenced in:

Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.9        111           2
 C cysteine            2.4         39           1
 D aspartate           3.6         59           2
 E glutamate           6.3        102           4
 F phenylalanine       3.2         52           2
 G glycine            10.1        164           8
 H histidine           2.5         40           1
 I isoleucine          4.1         66           2
 K lysine              4.2         68           2
 L leucine            10.1        164           3
 M methionine          2.5         41           2
 N asparagine          4.0         65           2
 P proline             7.8        126           3
 Q glutamine           3.9         63           3
 R arginine            5.3         86           2
 S serine              8.6        140           3
 T threonine           4.6         74           2
 V valine              5.6         90           2
 W tryptophan          2.0         33           2
 Y tyrosine            2.3         37           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   anaplastic lymphoma kinase 
LTK                   0.267   leukocyte receptor tyrosine kinase isoform 1 precurs...
LTK                   0.228   leukocyte receptor tyrosine kinase isoform 2 precurs...
LTK                   0.126   leukocyte receptor tyrosine kinase isoform 3 precur...
ROS1                  0.083   proto-oncogene c-ros-1 protein precursor 
IGF1R                 0.077   insulin-like growth factor 1 receptor precursor [Homo...
INSRR                 0.072   insulin receptor-related receptor precursor 
INSR                  0.071   insulin receptor isoform Short precursor 
INSR                  0.071   insulin receptor isoform Long precursor 
NTRK2                 0.062   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK2                 0.062   neurotrophic tyrosine kinase, receptor, type 2 isofo...
NTRK1                 0.062   neurotrophic tyrosine kinase, receptor, type 1 isofo...
NTRK1                 0.062   neurotrophic tyrosine kinase, receptor, type 1 isofor...
NTRK1                 0.062   neurotrophic tyrosine kinase, receptor, type 1 isofo...
MUSK                  0.061   skeletal muscle receptor tyrosine kinase 
NTRK3                 0.060   neurotrophic tyrosine kinase, receptor, type 3 isofo...
FES                   0.059   feline sarcoma oncogene isoform 4 
FES                   0.059   feline sarcoma oncogene isoform 3 
FES                   0.059   feline sarcoma oncogene isoform 2 
FES                   0.059   feline sarcoma oncogene isoform 1 
AXL                   0.058   AXL receptor tyrosine kinase isoform 2 
AXL                   0.058   AXL receptor tyrosine kinase isoform 1 
NTRK3                 0.057   neurotrophic tyrosine kinase, receptor, type 3 isofo...
FGFR3                 0.056   fibroblast growth factor receptor 3 isoform 3 precu...
FGFR3                 0.056   fibroblast growth factor receptor 3 isoform 2 precur...
FGFR3                 0.056   fibroblast growth factor receptor 3 isoform 1 precurs...
FER                   0.056   fer (fps/fes related) tyrosine kinase 
ROR1                  0.056   receptor tyrosine kinase-like orphan receptor 1 iso...
PTK7                  0.056   PTK7 protein tyrosine kinase 7 isoform a precursor [...
PTK7                  0.056   PTK7 protein tyrosine kinase 7 isoform d precursor [...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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