Search of human proteins with 31317236

Search of human proteins with 31317236

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|31317236 GSK-3 binding protein FRAT1 [Homo sapiens]
         (279 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|31317236 GSK-3 binding protein FRAT1 [Homo sapiens]                563   e-161
gi|16507243 GSK-3 binding protein FRAT2 [Homo sapiens]                337   5e-93
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     52   8e-07
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             50   2e-06
gi|112734870 hypothetical protein LOC57648 [Homo sapiens]              49   5e-06
gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo sa...    48   1e-05
gi|116268127 kinase non-catalytic C-lobe domain (KIND) containin...    47   1e-05
gi|118498345 AT-binding transcription factor 1 [Homo sapiens]          46   4e-05
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 46   4e-05
gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo sap...    44   1e-04
gi|237757326 synaptojanin 1 isoform d [Homo sapiens]                   44   1e-04
gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]             44   2e-04
gi|24431935 reticulon 4 isoform A [Homo sapiens]                       44   2e-04
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]    43   3e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    43   3e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   5e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    42   5e-04
gi|237757312 synaptojanin 1 isoform c [Homo sapiens]                   42   6e-04
gi|237757310 synaptojanin 1 isoform a [Homo sapiens]                   42   6e-04
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    42   6e-04
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]            42   6e-04
gi|151301171 RNA polymerase II transcription factor TAFII140 [Ho...    42   6e-04
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     42   8e-04
gi|24431933 reticulon 4 isoform B [Homo sapiens]                       42   8e-04
gi|47519490 reticulon 4 isoform D [Homo sapiens]                       42   8e-04
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    42   8e-04
gi|55741677 SET domain containing 1A [Homo sapiens]                    41   0.001
gi|54607077 ankyrin repeat domain 57 [Homo sapiens]                    41   0.001
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          40   0.002
gi|9945318 MAX binding protein [Homo sapiens]                          40   0.002

>gi|31317236 GSK-3 binding protein FRAT1 [Homo sapiens]
          Length = 279

 Score =  563 bits (1450), Expect = e-161
 Identities = 279/279 (100%), Positives = 279/279 (100%)

Query: 1   MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP 60
           MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP
Sbjct: 1   MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP 60

Query: 61  ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR 120
           ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR
Sbjct: 61  ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR 120

Query: 121 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR 180
           VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR
Sbjct: 121 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR 180

Query: 181 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL 240
           RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL
Sbjct: 181 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL 240

Query: 241 SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS 279
           SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS
Sbjct: 241 SAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLVPGS 279


>gi|16507243 GSK-3 binding protein FRAT2 [Homo sapiens]
          Length = 233

 Score =  337 bits (865), Expect = 5e-93
 Identities = 181/243 (74%), Positives = 185/243 (76%), Gaps = 31/243 (12%)

Query: 1   MPCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSP 60
           MPCRREEEEEAGEEAEGEEEE+DSFLLLQQSV LGSSGEVDRLVAQIGETLQLDAAQ SP
Sbjct: 1   MPCRREEEEEAGEEAEGEEEEDDSFLLLQQSVTLGSSGEVDRLVAQIGETLQLDAAQDSP 60

Query: 61  ASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGR 120
           ASPC PPG PLRAPGPLAAAVPADKAR PAVPLLLPPA AETVGPAP G LRCALGDRGR
Sbjct: 61  ASPCAPPGVPLRAPGPLAAAVPADKARPPAVPLLLPPASAETVGPAPSGALRCALGDRGR 120

Query: 121 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASR 180
           VRGRAAPYCVAE+A GPSA                        L GPCRRGWLR A  SR
Sbjct: 121 VRGRAAPYCVAEVAAGPSA------------------------LPGPCRRGWLRDAVTSR 156

Query: 181 RLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPL 240
           RLQQRR +Q   R GDDDPHRLLQQLVLSGNLIKEAVRRL      + A        GP 
Sbjct: 157 RLQQRRWTQAGARAGDDDPHRLLQQLVLSGNLIKEAVRRLQRAVAAVAA-------TGPA 209

Query: 241 SAP 243
           SAP
Sbjct: 210 SAP 212


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 68/229 (29%), Positives = 88/229 (38%), Gaps = 41/229 (17%)

Query: 60  PASPCGPPGAPLRA--------------PGPLAAAVPADKARSPAVPLLLPPALAETVGP 105
           PA P  P GAP  A              P P+AAA PA   R+ A     PP    + GP
Sbjct: 109 PAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPP----SPGP 164

Query: 106 APPGV-LRCALGDRGRVRGRAAPYCVAELA----TGPSALS----PLPPQADLDGPPGAG 156
           A PG   + A          AAP  VA  A      P A++    PLPP      PP   
Sbjct: 165 AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQ 224

Query: 157 KQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEA 216
           +   PQP   P   G +R   A+R +  R   +    +G              G L +  
Sbjct: 225 QPPPPQP-QPPPEGGAVRAGGAARPVSLREVVRYLGGSGG-----------AGGRLTRGR 272

Query: 217 VRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGR 265
           V+ L       R +L +R  LG L+ P  + P  R+P AA + P  S R
Sbjct: 273 VQGLLEEEAAARGRL-ERTRLGALALPRGDRPG-RAPPAASARPSRSKR 319



 Score = 34.7 bits (78), Expect = 0.095
 Identities = 44/142 (30%), Positives = 54/142 (38%), Gaps = 35/142 (24%)

Query: 53  LDAAQHSPASP--CGPPGAPLRAPGPLAAAVPADKARSPAV-PLLLPPALAETVGPAPPG 109
           L A   +PA+P    PP  P RAP P  AA      R P + P   PPA  +   P PP 
Sbjct: 177 LAAPPPAPAAPPAVAPPAGPRRAPPPAVAA------REPPLPPPPQPPAPPQQQQPPPPQ 230

Query: 110 VLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCR 169
                 G   R  G A P  + E+               L G  GAG         G   
Sbjct: 231 PQPPPEGGAVRAGGAARPVSLREVV------------RYLGGSGGAG---------GRLT 269

Query: 170 RGWLRG-----AAASRRLQQRR 186
           RG ++G     AAA  RL++ R
Sbjct: 270 RGRVQGLLEEEAAARGRLERTR 291


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 85/301 (28%), Positives = 101/301 (33%), Gaps = 38/301 (12%)

Query: 2    PCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQ-IGETLQLDAAQHSP 60
            P +R E    G  A G   E  S +  +         E  RLV    G T  L  A+ S 
Sbjct: 727  PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS 786

Query: 61   A-SPCGPPGAPLRAPG-PLAAAVPADK-ARSPAVPLLLPPALAETVGPAPPGVLRCALGD 117
              SP GP G     PG P   A P+   A  P  P   P   A    P P   L  A   
Sbjct: 787  QRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALA--- 843

Query: 118  RGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQG--IPQPLSGPCRRGWLRG 175
                 GR AP      +  P+  SP  P       PGA   G  +  P SG   R +   
Sbjct: 844  -----GRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESG---RYYFVE 895

Query: 176  AAASRRLQ----QRRGSQPETR---TGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRL--- 225
            A    RL+       G   E     +    PHR+   L L   L   A   + S  L   
Sbjct: 896  APRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPS 955

Query: 226  ---------QLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTGDGVLV 276
                     QL       PL G    PV   P+P  P   C+ P +SG  Q   G G L 
Sbjct: 956  PGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQ--PGKGSLF 1013

Query: 277  P 277
            P
Sbjct: 1014 P 1014


>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
          Length = 1094

 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 72/279 (25%), Positives = 95/279 (34%), Gaps = 69/279 (24%)

Query: 22   EDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQ-HSPASPCGPPGAPLRAPGPLAAA 80
            E++F  +      G SG  + + +    +    A Q   P SP  PP  P  AP   A++
Sbjct: 791  EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP---ASS 847

Query: 81   VPADKARSP------------------AVPLLLPPALA----ETVGPAPPGVLRCALGD- 117
             P   A+ P                    PL+ P  L      +VG AP G    ALG  
Sbjct: 848  APGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVG-APGGAPTPALGPS 906

Query: 118  ------RGRVRGRAAP--------YCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQP 163
                  R  + GRA+P        +    L     A S     A  +GPP A     P+P
Sbjct: 907  APQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAE----PRP 962

Query: 164  LSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSR 223
               P        +  SR+LQ  R   PET            Q  L  NL+ E        
Sbjct: 963  PQSPASTASFIFSKGSRKLQLERPVSPET------------QADLQRNLVAE-------- 1002

Query: 224  RLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGA 262
               LR+   QRP   P  +P   PP  R P      P +
Sbjct: 1003 ---LRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPAS 1038


>gi|156523244 membrane-associated ring finger (C3HC4) 11 [Homo
           sapiens]
          Length = 402

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 43/141 (30%), Positives = 54/141 (38%), Gaps = 14/141 (9%)

Query: 56  AQHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCAL 115
           A+   A P  PP  P   P P     P + A  PA P  LPP       PA P     A 
Sbjct: 15  AESGDAEP--PPQPP---PPPPPTPPPGEPAPVPAAPRYLPPL------PASPETPERAA 63

Query: 116 GDRGRVRGRAAPYC--VAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWL 173
           G    + G  AP C    EL   P  L P   +    G  G G + +P+  +     G  
Sbjct: 64  GPSEPL-GEVAPRCRGADELPPPPLPLQPAGQEVAAAGDSGEGPRRLPEAAAAKGGPGES 122

Query: 174 RGAAASRRLQQRRGSQPETRT 194
              A   R ++  G QPETR+
Sbjct: 123 EAGAGGERERRGAGDQPETRS 143


>gi|116268127 kinase non-catalytic C-lobe domain (KIND) containing 1
           isoform a [Homo sapiens]
          Length = 1749

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 47/162 (29%), Positives = 63/162 (38%), Gaps = 19/162 (11%)

Query: 5   REEEEEAGEEAEGEEEEEDSFLLLQQSVALGSS-------GEVDRLVAQIGETLQLDAAQ 57
           +EE EE G + EGE EE+ S      S +L +        G        +G ++Q D+AQ
Sbjct: 697 QEESEERGGQREGEGEEKLSLEAHAGSPSLKTPDGPVPGPGPQGAAPEPLGASVQRDSAQ 756

Query: 58  HSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGD 117
                PC PP AP   P   ++A P     +P       P       P PPGV       
Sbjct: 757 ---GRPCPPPQAPANQPEGASSAAPGSPVPAPPTKASALPVEQGPAEPIPPGVA------ 807

Query: 118 RGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQG 159
            G +R  A     A    GP    P PP++     PG   +G
Sbjct: 808 SGGLRPDALGPTTAH--HGPRH-PPKPPRSKATERPGQEPEG 846


>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
          Length = 3703

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 49/175 (28%), Positives = 73/175 (41%), Gaps = 21/175 (12%)

Query: 60   PASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRG 119
            P +P  PP  P   P PL AA P   A +PA+P   PP  + T+ PA P V    L    
Sbjct: 2034 PQTPEPPPPPPPPPPPPLPAA-PPQPASTPAIPASAPPITSPTIAPAQPSVPLTQLS--- 2089

Query: 120  RVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAAS 179
             +      +    + T P  L  LP Q     PP   + G  +PL  P     L     +
Sbjct: 2090 -MPMELPIFSPLMMQTMP--LQTLPAQL----PP---QLGPVEPL--PADLAQLYQHQLN 2137

Query: 180  RRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQR 234
              L Q++  +P TR  DD    L Q   ++ +  +E ++ +       ++ LPQ+
Sbjct: 2138 PTLLQQQNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMAD-----KSGLPQK 2187



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 14/18 (77%), Positives = 15/18 (83%)

Query: 6   EEEEEAGEEAEGEEEEED 23
           EEEEEA EE E EEEEE+
Sbjct: 467 EEEEEAEEEEEEEEEEEE 484



 Score = 28.9 bits (63), Expect = 5.2
 Identities = 13/18 (72%), Positives = 14/18 (77%)

Query: 6   EEEEEAGEEAEGEEEEED 23
           EEEEE  EE E EEEEE+
Sbjct: 466 EEEEEEAEEEEEEEEEEE 483



 Score = 28.1 bits (61), Expect = 8.9
 Identities = 13/17 (76%), Positives = 14/17 (82%)

Query: 7   EEEEAGEEAEGEEEEED 23
           EEEE  EEAE EEEEE+
Sbjct: 464 EEEEEEEEAEEEEEEEE 480


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 45.8 bits (107), Expect = 4e-05
 Identities = 47/169 (27%), Positives = 64/169 (37%), Gaps = 20/169 (11%)

Query: 6   EEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCG 65
           +++E+  +++E E++ +        S    ++    +   Q     Q+ A       P G
Sbjct: 355 DDDEDDSDDSEAEKQSQKQHKEESHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLG 414

Query: 66  PPGAP-LRAPGPLAAAVPADKARSPAVPLLLPPALAETVGP----APPGVLRCALGDRGR 120
           PP AP LR PGP     P     +P  P L PP +    GP     PPG         GR
Sbjct: 415 PPPAPPLRPPGPPTGLPPGPPPGAP--PFLRPPGMPGLRGPLPRLLPPG------PPPGR 466

Query: 121 VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCR 169
             G   P     L  GP    P PP+     PP     GIP P  G  R
Sbjct: 467 PPG-PPPGPPPGLPPGPPPRGP-PPRLPPPAPP-----GIPPPRPGMMR 508



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 22/52 (42%), Positives = 26/52 (50%), Gaps = 2/52 (3%)

Query: 60  PASPCG-PPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGV 110
           P  P G PPG P R P P     PA     P  P ++ P L   +GPAPPG+
Sbjct: 472 PGPPPGLPPGPPPRGPPPRLPP-PAPPGIPPPRPGMMRPPLVPPLGPAPPGL 522


>gi|239745807 PREDICTED: keratin associated protein 4-9 [Homo
           sapiens]
          Length = 254

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 37/119 (31%), Positives = 44/119 (36%), Gaps = 12/119 (10%)

Query: 59  SPASPC----GPPGAPLRAPGPLAAAVPADKARSPAV------PLLLPPALAETVGPAPP 108
           +PA  C    GP  A LRA  PLA A  A   R PA       P  + PA       +P 
Sbjct: 75  APAVVCPAAAGPSAASLRAANPLAVAPAA--VRRPAATLGAASPAAVAPAAVCPAAASPS 132

Query: 109 GVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGP 167
               CA          A+P   A LA  P+A +P            A    I QP+S P
Sbjct: 133 AASLCAASPTAAAPAAASPAAAAPLAVNPAAAAPAAACVQSVAESPATPLAIAQPVSSP 191



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 33/97 (34%), Positives = 44/97 (45%), Gaps = 14/97 (14%)

Query: 59  SPASPC----GPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALA-------ETVGPAP 107
           +PA+ C     P  A L A  P AAA PA  + + A PL + PA A       ++V  +P
Sbjct: 120 APAAVCPAAASPSAASLCAASPTAAA-PAAASPAAAAPLAVNPAAAAPAAACVQSVAESP 178

Query: 108 PGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLP 144
              L  A+          AP  V  LA  P+AL+ LP
Sbjct: 179 ATPL--AIAQPVSSPAAPAPCAVPPLAAEPTALAYLP 213



 Score = 32.7 bits (73), Expect = 0.36
 Identities = 29/87 (33%), Positives = 34/87 (39%), Gaps = 9/87 (10%)

Query: 65  GPPGAPLRAPGPLAAA-------VPADKARSPAV--PLLLPPALAETVGPAPPGVLRCAL 115
           GP  A L A  PL  A       V    A +PAV  P    P+ A      P  V   A+
Sbjct: 45  GPSAASLCAANPLVPAPAAVRPPVAGPPATAPAVVCPAAAGPSAASLRAANPLAVAPAAV 104

Query: 116 GDRGRVRGRAAPYCVAELATGPSALSP 142
                  G A+P  VA  A  P+A SP
Sbjct: 105 RRPAATLGAASPAAVAPAAVCPAAASP 131



 Score = 29.6 bits (65), Expect = 3.1
 Identities = 35/113 (30%), Positives = 41/113 (36%), Gaps = 4/113 (3%)

Query: 55  AAQHSPASPCGPPGAPLRAP--GPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLR 112
           AA    A+P  P  A +R P  GP A A PA    + A P       A  +  AP  V R
Sbjct: 48  AASLCAANPLVPAPAAVRPPVAGPPATA-PAVVCPAAAGPSAASLRAANPLAVAPAAVRR 106

Query: 113 CALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLS 165
            A           AP  V   A  PSA S L   +     P A       PL+
Sbjct: 107 PAATLGAASPAAVAPAAVCPAAASPSAAS-LCAASPTAAAPAAASPAAAAPLA 158



 Score = 29.3 bits (64), Expect = 4.0
 Identities = 26/102 (25%), Positives = 37/102 (36%), Gaps = 9/102 (8%)

Query: 55  AAQHSPASPCGPPGAPLRAPGPLAAAVPADKARS-------PAVPLLLPPALAETVGPAP 107
           AA   PA+  G       AP  +  A  +  A S        A P    PA A  +   P
Sbjct: 102 AAVRRPAATLGAASPAAVAPAAVCPAAASPSAASLCAASPTAAAPAAASPAAAAPLAVNP 161

Query: 108 PGVLRCALGDRGRVRGRAAPYCVAELATGPSALSP--LPPQA 147
                 A   +      A P  +A+  + P+A +P  +PP A
Sbjct: 162 AAAAPAAACVQSVAESPATPLAIAQPVSSPAAPAPCAVPPLA 203



 Score = 28.1 bits (61), Expect = 8.9
 Identities = 32/89 (35%), Positives = 36/89 (40%), Gaps = 9/89 (10%)

Query: 55  AAQHSPASPCGPPGAPLRAP--GPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLR 112
           AA+ S   P   P A +R P  GP AAA PA    + A P       A  + PAP  V  
Sbjct: 9   AAKTSVRRPAAAPAA-VRPPAAGPPAAA-PAVVYPAAAGPSAASLCAANPLVPAPAAVRP 66

Query: 113 CALGDRGRVRGRAAPYCVAELATGPSALS 141
              G         AP  V   A GPSA S
Sbjct: 67  PVAGPPA-----TAPAVVCPAAAGPSAAS 90


>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
          Length = 1526

 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 60/220 (27%), Positives = 83/220 (37%), Gaps = 24/220 (10%)

Query: 60   PASPCGPPGAPLRAPGPLAA-AVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDR 118
            P+ P  P  AP R PGP +A + P D   +  +P   P    E   P PP  +       
Sbjct: 1057 PSLPIRPSRAPSRTPGPPSAQSSPIDAQPATPLPQKDPAQPLEPKRPPPPRPVAPPT--- 1113

Query: 119  GRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRG--- 175
                 R AP    +    PS  S   PQA L GP  AG       +  P R G +     
Sbjct: 1114 -----RPAP---PQRPPPPSGRSQPSPQAGLAGPGPAGYSTARPTI--PPRAGVISAPQS 1163

Query: 176  ---AAASRRLQQRRGSQPETRTGDDD-PHRLLQQLVL-SGNLIKEAVRRLHSRRLQLRAK 230
               A+A R   + +    ET  G    P  L  Q      + +    +RL    + + A 
Sbjct: 1164 HARASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVPVAAP 1223

Query: 231  LPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRT 270
            +PQ      L  P   PP  RS  +  S+  AS + Q++T
Sbjct: 1224 MPQSGPQPNLETPPQPPPRSRSSHSLPSE--ASSQPQVKT 1261


>gi|55769533 PRKC, apoptosis, WT1, regulator [Homo sapiens]
          Length = 340

 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 41/136 (30%), Positives = 56/136 (41%), Gaps = 22/136 (16%)

Query: 54  DAAQHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRC 113
           DAA   PA   G P A   A   L   +P     +PAVP               PG + C
Sbjct: 48  DAAGKPPAGALGTPAAA--AANELNNNLPGGAPAAPAVP--------------GPGGVNC 91

Query: 114 ALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGP-CRRGW 172
           A+G     R    P    +     SA +  PPQ D + P G  ++G     SGP  R+G 
Sbjct: 92  AVGSAMLTRAAPGPRRSEDEPPAASASAAPPPQRDEEEPDGVPEKG---KSSGPSARKG- 147

Query: 173 LRGAAASRRLQQRRGS 188
            +G    R+L+++R S
Sbjct: 148 -KGQIEKRKLREKRRS 162


>gi|24431935 reticulon 4 isoform A [Homo sapiens]
          Length = 1192

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 66/249 (26%), Positives = 89/249 (35%), Gaps = 50/249 (20%)

Query: 6   EEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCG 65
           +EEEE  EE E E+E+ +   +L++  A G S          G  L        P +P G
Sbjct: 33  DEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG 92

Query: 66  P-PGAPLRA--------PGPLAAAVPADKARSPAV--PLLLPPALAETVGPAPPGVLRCA 114
           P P AP  A        P P+++ VPA    S A   P  LP        P PP      
Sbjct: 93  PLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP------ 146

Query: 115 LGDRGRVRGRAAPYCVAELATGPSALSPLPPQAD-LDGPPGAGKQGIPQPLSGPCRRGWL 173
                                 P+++S   PQA+ +  PP       P   + P RRG  
Sbjct: 147 ---------------------PPASVS---PQAEPVWTPPAPAPAAPPSTPAAPKRRG-S 181

Query: 174 RGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQ 233
            G+           S+P  R+  ++     Q     GN I        S  L+  A LP 
Sbjct: 182 SGSVDETLFALPAASEPVIRSSAENMDLKEQ----PGNTISAGQEDFPSVLLETAASLPS 237

Query: 234 RPLLGPLSA 242
              L PLSA
Sbjct: 238 ---LSPLSA 243


>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
          Length = 753

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 57/217 (26%), Positives = 70/217 (32%), Gaps = 51/217 (23%)

Query: 57  QHSPASPCGPPGAPLRAPGPLAAAVPADKAR----SPAVPLLLPPALAETVGPAPPGVLR 112
           QH P SP  PP  P   P P A+A+          +PA P   P AL     PAP     
Sbjct: 312 QH-PQSPAVPPTYP-SGPPPAASALSTTPGNNGVPAPAAP---PSALGPKASPAP----- 361

Query: 113 CALGDRGRVRGRAAPYCVA---ELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCR 169
                     G  APY  A      +GPS   P PP     G  G G  G     S    
Sbjct: 362 ------SHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSS 415

Query: 170 RGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRA 229
            G   G        ++ G+   +    D P  +        N   +A             
Sbjct: 416 AGGGAG--------KQNGATSYSSVVADSPAEVALSSSGGNNASSQA------------- 454

Query: 230 KLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRA 266
                  LGP S P + PPS     +A +  GA G A
Sbjct: 455 -------LGPPSGPHNPPPSTSKEPSAAAPTGAGGVA 484


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 45/138 (32%), Positives = 52/138 (37%), Gaps = 35/138 (25%)

Query: 60  PASPCGPPGAPLR----------APGPLAAAVPADKARSPAVPL--LLPPALAETVGPAP 107
           PA P  PP A LR          AP P AAAV A    +PA P     P ALA   GP P
Sbjct: 116 PAGPA-PPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGP 174

Query: 108 -----------------PGVLRCALGDRGRVRG-RAAPYCVAELATGPSALSPLP----P 145
                            PG  +   G    +    AA   V+ +  GP+AL PLP    P
Sbjct: 175 GPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234

Query: 146 QADLDGPPGAGKQGIPQP 163
              +  PP  G    P P
Sbjct: 235 GTVIQTPPFVGAAAPPAP 252



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 48/145 (33%), Positives = 56/145 (38%), Gaps = 24/145 (16%)

Query: 55  AAQHSPASPCGP----PGAPLRAPGPLAAAVPADKARSP--------AVPLLLPPALAET 102
           AA  +PA+P  P    P AP  AP P   A PA  AR P        A P + PPA A+ 
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPA-PATLARPPGHPAGPPTAAPAVPPPAAAQN 305

Query: 103 VGP--APPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGI 160
            G   A P     A G  G V G+  P   A  A  P   +  P +     PP A     
Sbjct: 306 GGSAGAAPAPAPAAGGPAG-VSGQPGPGAAA-AAPAPGVKAESPKRVVQAAPPAAQTLAA 363

Query: 161 PQPLS-------GPCRRGWLRGAAA 178
             P S       GP  +G L   AA
Sbjct: 364 SGPASTAASMVIGPTMQGALPSPAA 388



 Score = 35.0 bits (79), Expect = 0.073
 Identities = 32/127 (25%), Positives = 45/127 (35%), Gaps = 21/127 (16%)

Query: 56  AQHSPASPCGPPGAPLRAPGPLAAAV---PADKARSPAVPLLLPPALAETVGPAPPGVLR 112
           A  +PA   G P      PGP AAA    P  KA SP   +   P  A+T+  + P    
Sbjct: 311 AAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST- 369

Query: 113 CALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGW 172
                             A +  GP+    LP  A +  P      G+P+  +G   +  
Sbjct: 370 -----------------AASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSL 412

Query: 173 LRGAAAS 179
            R   A+
Sbjct: 413 SRTPTAT 419



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 36/106 (33%), Positives = 39/106 (36%), Gaps = 9/106 (8%)

Query: 57  QHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVG------PAPPGV 110
           Q  P      P AP  AP P AA  PA  A +P  P   P  LA   G       A P V
Sbjct: 239 QTPPFVGAAAPPAPA-APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAV 297

Query: 111 LRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAG 156
              A    G   G AAP   A  A GP+ +S  P        P  G
Sbjct: 298 PPPAAAQNGGSAG-AAP-APAPAAGGPAGVSGQPGPGAAAAAPAPG 341



 Score = 28.5 bits (62), Expect = 6.8
 Identities = 34/103 (33%), Positives = 40/103 (38%), Gaps = 19/103 (18%)

Query: 67  PGAPLRAPGPL-AAAVPADKARSP-AVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGR 124
           PG  ++ P  + AAA PA  A SP A P    PA A    P PP     A     R  G 
Sbjct: 234 PGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP--PPPPPAPATLA-----RPPGH 286

Query: 125 AAPYCVAELATGPSALSP-LPPQADLDGPPGAGKQGIPQPLSG 166
            A         GP   +P +PP A       AG    P P +G
Sbjct: 287 PA---------GPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 10/123 (8%)

Query: 46  QIGETLQLDAAQHSPASPCGPPGAPLRAPGPLAA-AVPADKARSPAVPLLLPPALAETVG 104
           Q    L L   Q  P+ P  PP +PL  P P A  A+     ++P  P   PP  A    
Sbjct: 395 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 105 PAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPL 164
           PA P V   A         +A P     LA  P  + P PP +    P        P PL
Sbjct: 455 PASPPVSPSATPP-----SQAPP----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505

Query: 165 SGP 167
           + P
Sbjct: 506 AAP 508



 Score = 35.8 bits (81), Expect = 0.043
 Identities = 41/129 (31%), Positives = 48/129 (37%), Gaps = 22/129 (17%)

Query: 65  GPPGAPLRAPGP---LAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRV 121
           GP G    +P P   LAA  PA  +R PA PL    A    + P PP     A G     
Sbjct: 648 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-PWPP-----ATGP---- 697

Query: 122 RGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRR 181
            G A   C      GP + +P P    LD  P  G  G      G    G   GA++   
Sbjct: 698 -GSADGLCTIYETEGPESATPAP--GALDPGPSPGTSG------GKAAAGAGAGASSRSP 748

Query: 182 LQQRRGSQP 190
            Q R G  P
Sbjct: 749 KQARLGELP 757



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 18/115 (15%)

Query: 60  PASPCGPPGA--PLRAPGPLAA----AVPADKARSPAVPLLLPPALAETVGPAPPGVLRC 113
           PASP   P A  P +AP  LAA      P+  A  P  P   PP  A     APP  L  
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL-- 512

Query: 114 ALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIP-QPLSGP 167
                     +  P     LAT P    P PP +     P +    +P  PL+ P
Sbjct: 513 ---------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 558



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 38/124 (30%), Positives = 43/124 (34%), Gaps = 22/124 (17%)

Query: 60  PASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRG 119
           P SP   P  P +AP  LAA +       PA P L  P    T GP              
Sbjct: 551 PMSPLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD------------- 595

Query: 120 RVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQ----GIPQPLSGPCRRGWLRG 175
                + P     LA GP       P + L GP  AG        P+ L G    G   G
Sbjct: 596 --TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 652

Query: 176 AAAS 179
           AAAS
Sbjct: 653 AAAS 656



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 24/70 (34%), Positives = 30/70 (42%), Gaps = 8/70 (11%)

Query: 45  AQIGETLQLDAAQHSPASPCGPPGAPLRAPGPLA----AAVPADKARSP--AVPLLLPPA 98
           +Q   +L     Q  P+ P  PP +P   P P A    AA P   A+ P  A P L  P 
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 527

Query: 99  LAETVGPAPP 108
           L     P+PP
Sbjct: 528 LQAL--PSPP 535


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 10/123 (8%)

Query: 46  QIGETLQLDAAQHSPASPCGPPGAPLRAPGPLAA-AVPADKARSPAVPLLLPPALAETVG 104
           Q    L L   Q  P+ P  PP +PL  P P A  A+     ++P  P   PP  A    
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415

Query: 105 PAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPL 164
           PA P V   A         +A P     LA  P  + P PP +    P        P PL
Sbjct: 416 PASPPVSPSATPP-----SQAPP----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466

Query: 165 SGP 167
           + P
Sbjct: 467 AAP 469



 Score = 35.8 bits (81), Expect = 0.043
 Identities = 41/129 (31%), Positives = 48/129 (37%), Gaps = 22/129 (17%)

Query: 65  GPPGAPLRAPGP---LAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRV 121
           GP G    +P P   LAA  PA  +R PA PL    A    + P PP     A G     
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-PWPP-----ATGP---- 658

Query: 122 RGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRR 181
            G A   C      GP + +P P    LD  P  G  G      G    G   GA++   
Sbjct: 659 -GSADGLCTIYETEGPESATPAP--GALDPGPSPGTSG------GKAAAGAGAGASSRSP 709

Query: 182 LQQRRGSQP 190
            Q R G  P
Sbjct: 710 KQARLGELP 718



 Score = 33.9 bits (76), Expect = 0.16
 Identities = 36/115 (31%), Positives = 43/115 (37%), Gaps = 18/115 (15%)

Query: 60  PASPCGPPGA--PLRAPGPLAA----AVPADKARSPAVPLLLPPALAETVGPAPPGVLRC 113
           PASP   P A  P +AP  LAA      P+  A  P  P   PP  A     APP  L  
Sbjct: 416 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL-- 473

Query: 114 ALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIP-QPLSGP 167
                     +  P     LAT P    P PP +     P +    +P  PL+ P
Sbjct: 474 ---------AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 38/124 (30%), Positives = 43/124 (34%), Gaps = 22/124 (17%)

Query: 60  PASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRG 119
           P SP   P  P +AP  LAA +       PA P L  P    T GP              
Sbjct: 512 PMSPLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD------------- 556

Query: 120 RVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQ----GIPQPLSGPCRRGWLRG 175
                + P     LA GP       P + L GP  AG        P+ L G    G   G
Sbjct: 557 --TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 613

Query: 176 AAAS 179
           AAAS
Sbjct: 614 AAAS 617



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 24/70 (34%), Positives = 30/70 (42%), Gaps = 8/70 (11%)

Query: 45  AQIGETLQLDAAQHSPASPCGPPGAPLRAPGPLA----AAVPADKARSP--AVPLLLPPA 98
           +Q   +L     Q  P+ P  PP +P   P P A    AA P   A+ P  A P L  P 
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488

Query: 99  LAETVGPAPP 108
           L     P+PP
Sbjct: 489 LQAL--PSPP 496


>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
          Length = 1295

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 60/225 (26%), Positives = 80/225 (35%), Gaps = 35/225 (15%)

Query: 57   QHSPASPCGP-------PGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPG 109
            Q  PA P  P       P AP   P P     P   ARSPA      P   E   P  PG
Sbjct: 1096 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA------PTRKEFGAPKSPG 1149

Query: 110  VLRCALGDRGRVRGRAAPYCVAELA-TGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPC 168
              R     +  + GR+ P   A LA  GP+  S   P      PP AG    PQ  +   
Sbjct: 1150 TTR-----KDNI-GRSQPSPQAGLAGPGPAGYSTARPTI----PPRAGVISAPQSHAR-- 1197

Query: 169  RRGWLRGAAASRRLQQRRGSQPETRTGDDD-PHRLLQQLVLSG-NLIKEAVRRLHSRRLQ 226
                   A+A R   + +    ET  G    P  L  Q      + +    +RL    + 
Sbjct: 1198 -------ASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRLQEPLVP 1250

Query: 227  LRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRTG 271
            + A +PQ      L  P   PP  RS  +  S+  +  + +  +G
Sbjct: 1251 VAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEASSQPQQEQPSG 1295


>gi|237757310 synaptojanin 1 isoform a [Homo sapiens]
          Length = 1612

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 68/234 (29%), Positives = 85/234 (36%), Gaps = 41/234 (17%)

Query: 57   QHSPASPCGP-------PGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVG---PA 106
            Q  PA P  P       P AP   P P     P   ARSPA      P   E  G   P 
Sbjct: 1135 QKDPAQPLEPKRPPPPRPVAPPTRPAPPQRPPPPSGARSPA------PTRKEFGGIGAPP 1188

Query: 107  PPGVLRC---ALGDRGRVR----GRAAPYCVAELA-TGPSALSPLPPQADLDGPPGAGKQ 158
             PGV R    A    G  R    GR+ P   A LA  GP+  S   P      PP AG  
Sbjct: 1189 SPGVARREMEAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTI----PPRAGVI 1244

Query: 159  GIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDD-PHRLLQQLVL-SGNLIKEA 216
              PQ  +          A+A R   + +    ET  G    P  L  Q      + +   
Sbjct: 1245 SAPQSHA---------RASAGRLTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPP 1295

Query: 217  VRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAACSDPGASGRAQLRT 270
             +RL    + + A +PQ      L  P   PP  RS  +  S+  AS + Q++T
Sbjct: 1296 AQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSE--ASSQPQVKT 1347


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 36/118 (30%), Positives = 45/118 (38%), Gaps = 10/118 (8%)

Query: 51  LQLDAAQHSPASPCGPPGAPLRAPGPLAA-AVPADKARSPAVPLLLPPALAETVGPAPPG 109
           L L   Q  P+ P  PP +PL  P P A  A+     ++P  P   PP  A    PA P 
Sbjct: 625 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 684

Query: 110 VLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGP 167
           V   A         +A P     LA  P  + P PP +    P        P PL+ P
Sbjct: 685 VSPSATPP-----SQAPP----SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 733



 Score = 37.4 bits (85), Expect = 0.015
 Identities = 41/141 (29%), Positives = 56/141 (39%), Gaps = 24/141 (17%)

Query: 45  AQIGETLQLDAAQHSPASPCGPPGAPL-----RAPGPLAA-------AVPADKARSPAV- 91
           +Q   +L     Q  P+ P  PP +P      +AP PLAA       + PA    SP+  
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752

Query: 92  -PLLLPPALAE---TVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQA 147
            P  +PP LA     V P+PP  L  +         +  P     LAT P    P PP +
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMS------PLAKPPPQAPPALATPPLQALPSPPAS 806

Query: 148 DLDGPPGAGKQGIP-QPLSGP 167
                P +    +P  PL+ P
Sbjct: 807 FPGQAPFSPSASLPMSPLATP 827



 Score = 35.8 bits (81), Expect = 0.043
 Identities = 41/129 (31%), Positives = 48/129 (37%), Gaps = 22/129 (17%)

Query: 65   GPPGAPLRAPGP---LAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRV 121
            GP G    +P P   LAA  PA  +R PA PL    A    + P PP     A G     
Sbjct: 917  GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-PWPP-----ATGP---- 966

Query: 122  RGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRR 181
             G A   C      GP + +P P    LD  P  G  G      G    G   GA++   
Sbjct: 967  -GSADGLCTIYETEGPESATPAP--GALDPGPSPGTSG------GKAAAGAGAGASSRSP 1017

Query: 182  LQQRRGSQP 190
             Q R G  P
Sbjct: 1018 KQARLGELP 1026



 Score = 34.3 bits (77), Expect = 0.12
 Identities = 37/125 (29%), Positives = 52/125 (41%), Gaps = 13/125 (10%)

Query: 52  QLDAAQHSPASPCGPP--GAPLRAPGPLAAAVPADKARSPAV-----PLLLPP--ALAET 102
           Q  A+  SP+ P   P    PL+AP  L A+ P   + SPAV     PL + P  AL+  
Sbjct: 436 QTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSL 495

Query: 103 VGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQ 162
              +P   L   +      +   AP     L T P++L+  PP  +L        Q    
Sbjct: 496 ASHSPQAPLSSLIMPPLETQSSLAP---PSLQTPPASLT-TPPLENLPSLAPPPLQTASA 551

Query: 163 PLSGP 167
           PL+ P
Sbjct: 552 PLTTP 556



 Score = 32.7 bits (73), Expect = 0.36
 Identities = 30/108 (27%), Positives = 37/108 (34%), Gaps = 2/108 (1%)

Query: 59  SPASPCGPPGAPLR-APGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGD 117
           SP +   P G   R  P P  AA P      P+ PL  P  LA     APP  L+     
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPS-LQTLPSP 360

Query: 118 RGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLS 165
                 +A P         P +L  +PP            Q  P PL+
Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLA 408



 Score = 32.3 bits (72), Expect = 0.47
 Identities = 48/194 (24%), Positives = 65/194 (33%), Gaps = 22/194 (11%)

Query: 58  HSPASPCGPPGAPLRAP-GPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALG 116
           H    PC  P  PL+AP  PL    P   +     P   PPALA     +PP        
Sbjct: 557 HLETPPCPAP-CPLQAPPSPLTTPPPETPSSIATPPPQAPPALA-----SPP-------- 602

Query: 117 DRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGA 176
               ++G  +P  ++ LAT P    P      L  PP         PL+ P  +     A
Sbjct: 603 ----LQGLPSP-PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQA--PNA 655

Query: 177 AASRRLQQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPL 236
            A   LQ      P               +  S     +A   L +  LQ+    P  P 
Sbjct: 656 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPP 715

Query: 237 LGPLSAPVHEPPSP 250
           + P + P  + P P
Sbjct: 716 MSPSATPPPQAPPP 729



 Score = 30.8 bits (68), Expect = 1.4
 Identities = 38/124 (30%), Positives = 43/124 (34%), Gaps = 22/124 (17%)

Query: 60  PASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRG 119
           P SP   P  P +AP  LAA +       PA P L  P    T GP              
Sbjct: 820 PMSPLATP--PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD------------- 864

Query: 120 RVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQ----GIPQPLSGPCRRGWLRG 175
                + P     LA GP       P + L GP  AG        P+ L G    G   G
Sbjct: 865 --TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG-YDSGPEGG 921

Query: 176 AAAS 179
           AAAS
Sbjct: 922 AAAS 925



 Score = 28.1 bits (61), Expect = 8.9
 Identities = 22/55 (40%), Positives = 24/55 (43%), Gaps = 6/55 (10%)

Query: 60  PASPCGPPGA--PLRAPGPLAA----AVPADKARSPAVPLLLPPALAETVGPAPP 108
           PASP   P A  P +AP  LAA      P+  A  P  P   PP  A     APP
Sbjct: 680 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734


>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 251

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 46/143 (32%), Positives = 56/143 (39%), Gaps = 9/143 (6%)

Query: 59  SPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDR 118
           +PA+P   P  PL AP P      +    + AVP   PPA A    PA  G    A G R
Sbjct: 31  TPATPARSPRPPLCAPRPAPGRAQSPVPAAGAVP--SPPAAAHPARPALRGETP-APGRR 87

Query: 119 GR--VRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGPCRRGWLRGA 176
           GR   RG   P     L+  P     +       GPP    + +P P     RR WL   
Sbjct: 88  GRATTRGEVQPSVRPPLSHRPLRGGGMGRGRPGKGPPPNPSRRLP-PAPPGGRRTWLSAL 146

Query: 177 A---ASRRLQQRRGSQPETRTGD 196
           A   A+    +RR S P  R  D
Sbjct: 147 ATGPAAGGAGRRRRSPPVFRAAD 169


>gi|151301171 RNA polymerase II transcription factor TAFII140 [Homo
           sapiens]
          Length = 929

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 34/116 (29%), Positives = 52/116 (44%), Gaps = 12/116 (10%)

Query: 5   REEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIG---------ETLQLDA 55
           RE+E+   E+ E E+E+     +  + VAL  S  + RL  ++G         + +    
Sbjct: 723 REKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPE 782

Query: 56  AQHSPAS--PCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPG 109
           A+ +P+   P  PP AP  APGP+  + PA             PAL  + GPA  G
Sbjct: 783 AKPAPSQNRPKTPPPAPAPAPGPMLVS-PAPVPLPLLAQAAAGPALLPSPGPAASG 837


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 68/247 (27%), Positives = 81/247 (32%), Gaps = 58/247 (23%)

Query: 54  DAAQHSPASPCGPPGAP-----LRAPGPLAAAVPADKARSPAVP-------------LLL 95
           +A    PA P GP G+P     +   GP   A PA  A  P                ++ 
Sbjct: 695 EAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVG 754

Query: 96  PPALAETVGPAPPGVLRCALGDRGR-----------VRGRAAPYCVAELATGPSALSPLP 144
           P       GPA P       G RG              GR  P        GPS +S  P
Sbjct: 755 PTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGP-------PGPSGISGPP 807

Query: 145 PQADLDGPPG-AGKQGI--PQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRT----GDD 197
                 GPPG AGK+G+  P+   GP  R    GA         +G   E  T    G  
Sbjct: 808 ------GPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTP 861

Query: 198 DPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAAC 257
            P  LL    + G       R L        A     P  GPL   +  PP  R P  A 
Sbjct: 862 GPQGLLGAPGILGLPGSRGERGLPGV-----AGAVGEP--GPLG--IAGPPGARGPPGAV 912

Query: 258 SDPGASG 264
             PG +G
Sbjct: 913 GSPGVNG 919



 Score = 30.4 bits (67), Expect = 1.8
 Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 25/119 (21%)

Query: 49  ETLQLDAAQHSPASPCGPPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPP 108
           ++LQ +  +  PA   GP G     PGP       D    P  P            P PP
Sbjct: 23  QSLQEETVRKGPAGDRGPRGER-GPPGPPGR----DGEDGPTGP------------PGPP 65

Query: 109 GVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGPPGAGKQGIPQPLSGP 167
           G      G  G     AA Y    +  GP  +  + P+    GPPGA     PQ   GP
Sbjct: 66  G----PPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR----GPPGAAGAPGPQGFQGP 116


>gi|24431933 reticulon 4 isoform B [Homo sapiens]
          Length = 373

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 11/114 (9%)

Query: 6   EEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCG 65
           +EEEE  EE E E+E+ +   +L++  A G S          G  L        P +P G
Sbjct: 33  DEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG 92

Query: 66  P-PGAPLRA--------PGPLAAAVPADKARSPAV--PLLLPPALAETVGPAPP 108
           P P AP  A        P P+++ VPA    S A   P  LP        P PP
Sbjct: 93  PLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146


>gi|47519490 reticulon 4 isoform D [Homo sapiens]
          Length = 392

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 36/114 (31%), Positives = 47/114 (41%), Gaps = 11/114 (9%)

Query: 6   EEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCG 65
           +EEEE  EE E E+E+ +   +L++  A G S          G  L        P +P G
Sbjct: 33  DEEEEEEEEEEDEDEDLEELEVLERKPAAGLSAAPVPTAPAAGAPLMDFGNDFVPPAPRG 92

Query: 66  P-PGAPLRA--------PGPLAAAVPADKARSPAV--PLLLPPALAETVGPAPP 108
           P P AP  A        P P+++ VPA    S A   P  LP        P PP
Sbjct: 93  PLPAAPPVAPERQPSWDPSPVSSTVPAPSPLSAAAVSPSKLPEDDEPPARPPPP 146


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 43/159 (27%), Positives = 64/159 (40%), Gaps = 10/159 (6%)

Query: 2   PCRREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPA 61
           PC +++E++  +E E ++EEE+     ++      + E+  + A   E  +L     +P 
Sbjct: 352 PCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEM--MPAAEKEEAKLPPPPLTPP 409

Query: 62  SPCGPPGAP--LRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRG 119
           +P  PP  P    +P P     P      P +P   PP   E    +PP V+  A   R 
Sbjct: 410 APSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVP-ATCSRK 468

Query: 120 RVRGRAAPYCVAE---LATGPSALSP--LPPQADLDGPP 153
           R R    P   AE      GP   SP    P     GPP
Sbjct: 469 RGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPP 507



 Score = 32.7 bits (73), Expect = 0.36
 Identities = 56/260 (21%), Positives = 91/260 (35%), Gaps = 54/260 (20%)

Query: 41  DRLVAQIGETLQLDAAQHSPASPCGPPGAPLRAPG--------------------PLAAA 80
           +R+V  + E L+   A  +P S    P  P R+ G                      A  
Sbjct: 187 ERMVQALTELLRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVT 246

Query: 81  VPADKARSPAVPLLLPPALAETV-GPAP-PGV-------LRCALGDRGRVRGRAAPYCVA 131
           +P  +   P VP+       +   GP P PG         R   G RGR RG   P+ V 
Sbjct: 247 IPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRGRGRGGGLPF-VI 305

Query: 132 ELATGPSALSPLPPQADLDGPPGAGK-----QGIPQPLSGPCRRGWLRGAAASRRL---- 182
           +  +    +        L+   G G+     Q +PQ   G  + G        ++L    
Sbjct: 306 KFVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQRRVGSGQGGSPCWKKQEQKLDDEE 365

Query: 183 QQRRGSQPETRTGDDDPHRLLQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSA 242
           ++++  + + + G++   R + + ++     +EA             KLP  PL  P  +
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEA-------------KLPPPPLTPPAPS 412

Query: 243 PVH--EPPSPRSPRAACSDP 260
           P     PPS   P   C  P
Sbjct: 413 PPPPLPPPSTSPPPPLCPPP 432



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 55/226 (24%), Positives = 80/226 (35%), Gaps = 25/226 (11%)

Query: 32   VALGSSGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAPLR---APGPLAAAVPADKARS 88
            + +   G+V   +A  GE +     Q  P  P   P AP      PGPL   +P      
Sbjct: 2192 ILVNKLGQVFVKMAGEGEPVPPPVKQ-PPLPPTISPTAPTSWTLPPGPLLGVLPVVGVVR 2250

Query: 89   PAVPLLLPP-ALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLP--- 144
            PA P   PP  L  + GPA P      +       GR+ P             +P P   
Sbjct: 2251 PAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPP-------------APPPYKA 2297

Query: 145  PQADLDGPPGAGKQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRLLQ 204
            P+ D DG        +P   SG   R  ++       L   R  +P    G++ P  L +
Sbjct: 2298 PRLDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLDLDRPGEP---AGEESPGPLQE 2354

Query: 205  QLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSP 250
            +  L   L ++   ++      L  +       G  S+   EPPSP
Sbjct: 2355 RSPLL-PLPEDGPPQVPDGPPDLLLESQWHHYSGEASSSEEEPPSP 2399


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 33/109 (30%), Positives = 40/109 (36%), Gaps = 31/109 (28%)

Query: 53   LDAAQHSPASPCGP-----PGAPLRAP----GPLAAAVPADKARSPAVPLLLPPALAETV 103
            L   + SPA P GP     P APLR P    GP A A   D+  S  +PLL PP      
Sbjct: 1108 LPEQEASPARPAGPTEESPPSAPLRPPEPPAGPPAPAPRPDERPSSPIPLLPPP------ 1161

Query: 104  GPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPLPPQADLDGP 152
                            + R +   +   E+   P      PPQA   GP
Sbjct: 1162 ----------------KKRRKTVSFSAIEVVPAPEPPPATPPQAKFPGP 1194



 Score = 34.7 bits (78), Expect = 0.095
 Identities = 30/73 (41%), Positives = 35/73 (47%), Gaps = 12/73 (16%)

Query: 4    RREEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASP 63
            +REE EE GEE EGEEEEE+S           SS   D   A    +L+  A +  P  P
Sbjct: 1357 QREEGEEEGEE-EGEEEEEES---------SDSSSSSDGEGALRRRSLRSHARRRRPPPP 1406

Query: 64   CGPPGAPLRAPGP 76
              PP  P RA  P
Sbjct: 1407 --PPPPPPRAYEP 1417



 Score = 30.0 bits (66), Expect = 2.3
 Identities = 36/141 (25%), Positives = 49/141 (34%), Gaps = 17/141 (12%)

Query: 6    EEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQHSPASPCG 65
            E +  +  E+        S      S +  SS E     ++  E  +  AA  S + P  
Sbjct: 1026 ENDSTSDSESSSSSSSSSSSSSSSSSSSSSSSSESS---SEDEEEEERPAALPSASPP-- 1080

Query: 66   PPGAPLRAPGPLAAAVPADKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGRA 125
            P   P+  P P+   VP   A SP  P  LP   A    PA P                +
Sbjct: 1081 PREVPVPTPAPVEVPVPERVAGSPVTP--LPEQEASPARPAGP----------TEESPPS 1128

Query: 126  APYCVAELATGPSALSPLPPQ 146
            AP    E   GP A +P P +
Sbjct: 1129 APLRPPEPPAGPPAPAPRPDE 1149


>gi|54607077 ankyrin repeat domain 57 [Homo sapiens]
          Length = 525

 Score = 41.2 bits (95), Expect = 0.001
 Identities = 71/254 (27%), Positives = 95/254 (37%), Gaps = 38/254 (14%)

Query: 33  ALGSSGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAPLRAPGPLAAAV---------PA 83
           ALG    +  L  + G  L  +  QH   +  G P    RA       V         PA
Sbjct: 12  ALGPEAVLRFLAERGGRALHAELVQHFRGALGGEPEQRARARAHFKELVNAVATVRVDPA 71

Query: 84  DKARSPAVPLLLPPALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELATGPSALSPL 143
           D A+     + L     E  GP+ P       GD  R++  A P    +   GP A   L
Sbjct: 72  DGAKY----VHLKKRFCE--GPSEPS------GDPPRIQVTAEPEA-PDGPAGPEARDRL 118

Query: 144 PPQADLDGPPGAGKQ-GIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTGDDDPHRL 202
           P  A  +  PG G++ G  +P   P    W   +A +RR   RR  QP  RT    P   
Sbjct: 119 PDAAAPESLPGQGRELGEGEP---PAPAHWPPLSAGARRKNSRRDVQPLPRTPAPGPS-- 173

Query: 203 LQQLVLSGNLIKEAVRRLHSRRLQLRAKLPQRPLLGPLSAPVHEPPSPRSPRAAC---SD 259
            + L L  +  +EA R   S  +   A+ P R  L  L        SP+  R+ C   S 
Sbjct: 174 -EDLELPPHGCEEADR--GSSLVGATAQRPARQNLRDLVM----GSSPQLKRSVCPGGSS 226

Query: 260 PGASGRAQLRTGDG 273
           PG+S       G G
Sbjct: 227 PGSSSGGGRGRGGG 240


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 47/164 (28%), Positives = 62/164 (37%), Gaps = 18/164 (10%)

Query: 37  SGEVDRLVAQIGETLQLDAAQHSPASPCGPPGAPLRAPGPL-AAAVPADKARSPAVPLLL 95
           +G   +L  + G++  LD +   P  P G P      P P  A AV A  A+ P      
Sbjct: 260 AGARGKLSPRKGKSKTLDNSDLHPGPPAGSPPPLTLPPTPSPATAVTAASAQPPG----- 314

Query: 96  PPALAETVGPAPPGVLRCALGDRGRVRGRAAPYCVAELAT----GPSALSPLPPQADLDG 151
            PA   T+ P  PG+ R   G R   R R     ++ + T    GP    PLP      G
Sbjct: 315 -PAPPITLEPPAPGLKRGREGGRASTRDRKMLKFISGIFTKSTGGPPGSGPLP------G 367

Query: 152 PPGAGKQGIPQPLSGPCRRGWLRGAAASRRLQQRRGSQPETRTG 195
           PP        + L G   R   +    S+     R S PE R G
Sbjct: 368 PPSLSSGSGSRELLGAELRASPKAVINSQEWTLSR-SIPELRLG 410


>gi|9945318 MAX binding protein [Homo sapiens]
          Length = 582

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 48/169 (28%), Positives = 64/169 (37%), Gaps = 35/169 (20%)

Query: 5   REEEEEAGEEAEGEEEEEDSFLLLQQSVALGSSGEVDRLVAQIGETLQLDAAQ-HSPASP 63
           REE+E    E E E+E++ +  L                 A++  TL ++  +  +P  P
Sbjct: 24  REEQERLRLEQEREQEQKKANSL-----------------ARLAHTLPVEEPRMEAPPLP 66

Query: 64  CGPPGAPLRAPGPLAAAVPADKARSPAV-----PLLLPPALAETVGPAPPGVLRCAL-GD 117
             PP  P   P PLA   P      P V     PL  PP L     P P    + AL G 
Sbjct: 67  LSPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPAAAQPLPLAPRQPALVGA 126

Query: 118 RGRVRGRAAPYCVAELATGPSALSPLP--PQADLDGPPGAGKQGIPQPL 164
            G      AP     L + P   +P P  P +    PP     G P+PL
Sbjct: 127 PGLSIKEPAP-----LPSRPQVPTPAPLLPDSKATIPP----NGSPKPL 166


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.135    0.405 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,442,349
Number of Sequences: 37866
Number of extensions: 1000611
Number of successful extensions: 11947
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 190
Number of HSP's successfully gapped in prelim test: 796
Number of HSP's that attempted gapping in prelim test: 8436
Number of HSP's gapped (non-prelim): 3756
length of query: 279
length of database: 18,247,518
effective HSP length: 101
effective length of query: 178
effective length of database: 14,423,052
effective search space: 2567303256
effective search space used: 2567303256
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.