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Search of human proteins with 29570800
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
(832 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|29570800 cadherin-like 26 isoform a [Homo sapiens] 1682 0.0
gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens] 357 3e-98
gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens] 346 6e-95
gi|21361902 cadherin-like 26 isoform b [Homo sapiens] 325 1e-88
gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo sapi... 318 1e-86
gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo sapi... 318 2e-86
gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens] 308 2e-83
gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens] 307 2e-83
gi|4502719 cadherin 13 preproprotein [Homo sapiens] 304 3e-82
gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens] 293 4e-79
gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo sapi... 293 4e-79
gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo sap... 289 8e-78
gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo sap... 289 8e-78
gi|4826669 cadherin 15 preproprotein [Homo sapiens] 276 6e-74
gi|197313787 desmoglein 4 isoform 1 [Homo sapiens] 274 3e-73
gi|29789445 desmoglein 4 isoform 2 [Homo sapiens] 272 1e-72
gi|116534898 desmoglein 2 preproprotein [Homo sapiens] 239 6e-63
gi|119964718 desmoglein 3 preproprotein [Homo sapiens] 229 8e-60
gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens] 219 6e-57
gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens] 219 6e-57
gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens] 212 1e-54
gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens] 212 1e-54
gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens] 212 1e-54
gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens] 206 6e-53
gi|221316595 cadherin 17 precursor [Homo sapiens] 206 9e-53
gi|221316593 cadherin 17 precursor [Homo sapiens] 206 9e-53
gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens] 205 1e-52
gi|119703744 desmoglein 1 preproprotein [Homo sapiens] 196 6e-50
gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens] 196 7e-50
gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens] 195 2e-49
>gi|29570800 cadherin-like 26 isoform a [Homo sapiens]
Length = 832
Score = 1682 bits (4355), Expect = 0.0
Identities = 832/832 (100%), Positives = 832/832 (100%)
Query: 1 MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITT 60
MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITT
Sbjct: 1 MAMRSGRHPSLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITT 60
Query: 61 LELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHR 120
LELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHR
Sbjct: 61 LELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHR 120
Query: 121 PVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSA 180
PVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSA
Sbjct: 121 PVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSA 180
Query: 181 GQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIRLSGCLDYETAPQ 240
GQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIRLSGCLDYETAPQ
Sbjct: 181 GQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIRLSGCLDYETAPQ 240
Query: 241 FTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQD 300
FTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQD
Sbjct: 241 FTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQD 300
Query: 301 RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE 360
RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE
Sbjct: 301 RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE 360
Query: 361 ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA 420
ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA
Sbjct: 361 ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA 420
Query: 421 MDPDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQ 480
MDPDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQ
Sbjct: 421 MDPDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQ 480
Query: 481 TATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDN 540
TATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDN
Sbjct: 481 TATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDN 540
Query: 541 TWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASG 600
TWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASG
Sbjct: 541 TWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASG 600
Query: 601 LTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTL 660
LTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTL
Sbjct: 601 LTCVELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTL 660
Query: 661 VMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALG 720
VMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALG
Sbjct: 661 VMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALG 720
Query: 721 SWGYGKPFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYL 780
SWGYGKPFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYL
Sbjct: 721 SWGYGKPFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYL 780
Query: 781 PHVYSEEGECGGAPSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
PHVYSEEGECGGAPSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS
Sbjct: 781 PHVYSEEGECGGAPSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
>gi|14589889 cadherin 2, type 1 preproprotein [Homo sapiens]
Length = 906
Score = 357 bits (915), Expect = 3e-98
Identities = 250/799 (31%), Positives = 393/799 (49%), Gaps = 73/799 (9%)
Query: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSL 108
L+R KR WVI + L E GPFP+ + + ++ N+SL Y ++GPG D+ P G+F +
Sbjct: 154 LQRQKRDWVIPPINLPENSRGPFPQELVRIRSDRDKNLSLRYSVTGPGADQ-PPTGIFII 212
Query: 109 EDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEK 168
+G++ V +P+DRE F + V+ + G V+ + I + D+ND+ P+F +
Sbjct: 213 NPI-SGQLSVTKPLDREQIARFHLRAHAVDIN-GNQVENPIDIVINVIDMNDNRPEFLHQ 270
Query: 169 EFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLSGEI 227
+N TV E G + + A+D D+ N N + Y ++SQ P F ++ +G+I
Sbjct: 271 VWNGTVPEGSKPGTYVMTVTAIDADDPNALNGMLRYRIVSQAPSTPSPNMFTINNETGDI 330
Query: 228 -RLSGCLDYETAPQFTLLIRARDC-GEPS--LSSTTTVHVDVQEGNNHRPAFTQENYKVQ 283
++ LD E Q+TL+I+A D G P+ LS+T T + V + N++ P FT + +
Sbjct: 331 ITVAAGLDREKVQQYTLIIQATDMEGNPTYGLSNTATAVITVTDVNDNPPEFTAMTFYGE 390
Query: 284 IPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPL 343
+PE R V L V D+D P T AW A + I G+ G F I TDP +N+G++ V+KP+
Sbjct: 391 VPENRVDIIVANLTVTDKDQPHTPAWNAVYRISGGDPTGRFAIQTDPNSNDGLVTVVKPI 450
Query: 344 DYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIV 403
D+ET L + EN+ L +G PP+ ++ATVSV V D N+ P F P I+
Sbjct: 451 DFETNRMFVLTVAAENQVPLA---KGIQHPPQ---STATVSVTVIDVNENPYFAPNPKII 504
Query: 404 NKEEGARPGTLLGTFNAMDPD----SQIRYELVHDPANWVSVDKNSGVVITVEPIDRESP 459
+EEG GT+L TF A DPD IRY + DPANW+ +D +G + T+ +DRESP
Sbjct: 505 RQEEGLHAGTMLTTFTAQDPDRYMQQNIRYTKLSDPANWLKIDPVNGQITTIAVLDRESP 564
Query: 460 HVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLH 519
+V N+ Y A D+G PP + TGTL ++L DINDN P + P+ E CE+ ++
Sbjct: 565 NVKNNIYNATFLASDNGIPPMSGTGTLQIYLLDINDNAPQVLPQE--AETCETPDPNSIN 622
Query: 520 IEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL-LTLRSLPRGNYLVPLFI 578
I A D D++P + PF F+L + + W + R G +L L ++ L G Y VP+ I
Sbjct: 623 ITALDYDIDPNAGPFAFDLPLSPVTIKRNWTITRLNGDFAQLNLKIKFLEAGIYEVPIII 682
Query: 579 GDKQG--LSQKQTVHVRICPCASGLTCVEL-ADAEVGLHVGALFPVCAAFVALAVALLFL 635
D S + V++C C S C ++ GL GA+ + + L + +L
Sbjct: 683 TDSGNPPKSNISILRVKVCQCDSNGDCTDVDRIVGAGLGTGAIIAILLCIIILLILVLMF 742
Query: 636 LRCYFVLEPKRHGCSV---SNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAA 692
+ + +R + D+ ++ Y+ E G Q + + Q+P + A
Sbjct: 743 VVWMKRRDKERQAKQLLIDPEDDVRDNILKYDEEGGGEEDQDYDLSQLQQPDTV--EPDA 800
Query: 693 GPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATMHRQLL 752
G++ ++E P IH+ P YP +
Sbjct: 801 IKPVGIRRMDERP------------------------------IHAEPQYPVRS-----A 825
Query: 753 APVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLASLEQ--EL 806
AP G + + +N+ L A ++DP P+ V+ EG A SLSSL S E
Sbjct: 826 APHPGDIGDFINEGLKAA---DNDPTAPPYDSLLVFDYEGSGSTAGSLSSLNSSSSGGEQ 882
Query: 807 QPDLLDSLGSKATPFEEIY 825
D L+ G + ++Y
Sbjct: 883 DYDYLNDWGPRFKKLADMY 901
>gi|14589893 cadherin 4, type 1 preproprotein [Homo sapiens]
Length = 916
Score = 346 bits (887), Expect = 6e-95
Identities = 241/824 (29%), Positives = 395/824 (47%), Gaps = 72/824 (8%)
Query: 23 QVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM 82
+V +D D L + + LRR KR WVI + + E GPFP+ + + ++
Sbjct: 138 KVVALDPSPPPKDTLLPWPQHQNANGLRRRKRDWVIPPINVPENSRGPFPQQLVRIRSDK 197
Query: 83 SYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTG 142
++ + Y I+G G D+ P + +FS+ D +GR+YV RP+DRE S+ + V+ +
Sbjct: 198 DNDIPIRYSITGVGADQ-PPMEVFSI-DSMSGRMYVTRPMDREEHASYHLRAHAVDMNGN 255
Query: 143 KIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQV 202
K V+ + I + D+ND+ P+F + +N +V E G + + A D D+ T N V
Sbjct: 256 K-VENPIDLYIYVIDMNDNRPEFINQVYNGSVDEGSKPGTYVMTVTANDADDSTTANGMV 314
Query: 203 LYFLISQTPLL-KESGFRVDRLSGEI-RLSGCLDYETAPQFTLLIRARDCG---EPSLSS 257
Y +++QTP ++ F ++ +G+I ++ LD E Q+T++++A D LS+
Sbjct: 315 RYRIVTQTPQSPSQNMFTINSETGDIVTVAAGLDREKVQQYTVIVQATDMEGNLNYGLSN 374
Query: 258 TTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILH 317
T T + V + N++ P FT + ++PE R V L V DRD P + W A + I+
Sbjct: 375 TATAIITVTDVNDNPPEFTASTFAGEVPENRVETVVANLTVMDRDQPHSPNWNAVYRIIS 434
Query: 318 GNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKA 377
G+ GHF + TDP TNEG++ V+K +DYE A L ++V N+ L + Q
Sbjct: 435 GDPSGHFSVRTDPVTNEGMVTVVKAVDYELNRAFMLTVMVSNQAPLASGIQMSFQ----- 489
Query: 378 AASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVH 433
++A V++ + D N+ P F ++ EEG PGT+L TF+A+DPD +RY +
Sbjct: 490 -STAGVTISIMDINEAPYFPSNHKLIRLEEGVPPGTVLTTFSAVDPDRFMQQAVRYSKLS 548
Query: 434 DPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDI 493
DPA+W+ ++ +G + T +DRES + N+ Y A D+G PP + TGTL ++L DI
Sbjct: 549 DPASWLHINATNGQITTAAVLDRESLYTKNNVYEATFLAADNGIPPASGTGTLQIYLIDI 608
Query: 494 NDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGR 553
NDN P L P+ ++CE ++I A D D++P P+ FEL W + R
Sbjct: 609 NDNAPELLPKE--AQICEKPNLNAINITAADADVDPNIGPYVFELPFVPAAVRKNWTITR 666
Query: 554 NWGQSVEL-LTLRSLPRGNYLVPLFIGDKQG--LSQKQTVHVRICPCASGLTCVEL-ADA 609
G +L L + L G Y VP+ + D LS + V++CPC C + A A
Sbjct: 667 LNGDYAQLSLRILYLEAGMYDVPIIVTDSGNPPLSNTSIIKVKVCPCDDNGDCTTIGAVA 726
Query: 610 EVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSV---SNDEGHQTLVMYNAE 666
GL GA+ + + L +L + E +RH + D+ ++ Y+ E
Sbjct: 727 AAGLGTGAIVAILICILILLTMVLLFVMWMKRREKERHTKQLLIDPEDDVRDNILKYDEE 786
Query: 667 SKGTSAQTWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGK 726
G Q + + Q+P + + P GV+ ++E P
Sbjct: 787 GGGEEDQDYDLSQLQQPEAMGHVPSKAP--GVRRVDERP--------------------- 823
Query: 727 PFEPRSVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH---- 782
+ + P YP M P G + + +N+ L A ++DP P+
Sbjct: 824 ---------VGAEPQYPIRPM-----VPHPGDIGDFINEGLRAA---DNDPTAPPYDSLL 866
Query: 783 VYSEEGECGGAPSLSSL-ASLEQELQPDLLDSLGSKATPFEEIY 825
V+ EG A S+SSL +S + D L+ G + ++Y
Sbjct: 867 VFDYEGSGSTAGSVSSLNSSSSGDQDYDYLNDWGPRFKKLADMY 910
>gi|21361902 cadherin-like 26 isoform b [Homo sapiens]
Length = 165
Score = 325 bits (833), Expect = 1e-88
Identities = 159/159 (100%), Positives = 159/159 (100%)
Query: 674 TWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSV 733
TWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSV
Sbjct: 7 TWSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSV 66
Query: 734 KNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPHVYSEEGECGGA 793
KNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPHVYSEEGECGGA
Sbjct: 67 KNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPHVYSEEGECGGA 126
Query: 794 PSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
PSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS
Sbjct: 127 PSLSSLASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 165
>gi|13435364 desmocollin 2 isoform Dsc2a preproprotein [Homo
sapiens]
Length = 901
Score = 318 bits (815), Expect = 1e-86
Identities = 243/808 (30%), Positives = 386/808 (47%), Gaps = 50/808 (6%)
Query: 30 VQQETDDLTKQ-TKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSL 88
++ +T L K+ TKEK+ LRR+KRRW + E GPFP + ++ ++ + N ++
Sbjct: 113 LEHQTKVLKKRHTKEKV---LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTI 169
Query: 89 MYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTS 148
Y I GPGVD+ P LF +E + G +Y RPVDRE SF + G +
Sbjct: 170 YYSIRGPGVDQEPR-NLFYVE-RDTGNLYCTRPVDREQYESFEI-IAFATTPDGYTPELP 226
Query: 149 LIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLIS 208
L I+I D ND+ P F E+ + T+ EN G + Q+ A D DE +T ++++ Y +I
Sbjct: 227 LPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIG 286
Query: 209 QTPLLKESGFRVDRLSGEIRL-SGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDV 265
Q P + F + +G I S LD E ++ L I+ +D L +T+T +++
Sbjct: 287 QVPP-SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINI 345
Query: 266 QEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFD 325
+ N+H P FT+ +Y + E +LR+ V+D+D T+ WRA + IL GNE G+F
Sbjct: 346 DDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFK 405
Query: 326 ISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSV 385
I TD +TNEG+L V+KPL+YE + L I V NE + PR A ++ATV+V
Sbjct: 406 IVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPF-----SREASPRSAMSTATVTV 460
Query: 386 QVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDPANWVSV 441
V D ++ P +P V +E A GT + A DP+ S IRY+ + DP WV++
Sbjct: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
Query: 442 DKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLR 501
D+N+G + +DRE+ + N Y I + A D G +T TGTL + L D+NDN P +
Sbjct: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
Query: 502 PRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL 561
++ + +C+ + I A DPD PF F L+++ + W+L + L
Sbjct: 579 KKT--VIICKPTM-SSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL 635
Query: 562 LTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPV 621
P G+Y+VP+ + D+ G+S ++ V +C C + C D +G L
Sbjct: 636 SYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKW 695
Query: 622 CAAFVALAVALLFLLRCYFVLEPKRHGCS-----VSNDEGHQTLVMYNAESKGT----SA 672
+ L +ALLF + F L G S + +D Q L++ N E+ G SA
Sbjct: 696 AILAILLGIALLFCI--LFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSA 753
Query: 673 QTWSDVEGQRPALLIC-TAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPR 731
++ A +C T +G G ++ E+ S R G G
Sbjct: 754 NGFTTQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQTSESCR------GAGHHHTLD 807
Query: 732 SVKNIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPHV--YSEEGE 789
S + H+ + R + L +K+++ N E+ +V Y+ EG
Sbjct: 808 SCRGGHT-----EVDNCRYTYSEWHSFTQPRLGEKVYLCNQDENHKHAQDYVLTYNYEGR 862
Query: 790 CGGAPSLSSLASLEQELQPDLLDSLGSK 817
A S+ + ++E + LD+L K
Sbjct: 863 GSVAGSVGCCSERQEEDGLEFLDNLEPK 890
>gi|13435366 desmocollin 2 isoform Dsc2b preproprotein [Homo
sapiens]
Length = 847
Score = 318 bits (814), Expect = 2e-86
Identities = 213/653 (32%), Positives = 332/653 (50%), Gaps = 32/653 (4%)
Query: 30 VQQETDDLTKQ-TKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSL 88
++ +T L K+ TKEK+ LRR+KRRW + E GPFP + ++ ++ + N ++
Sbjct: 113 LEHQTKVLKKRHTKEKV---LRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTI 169
Query: 89 MYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTS 148
Y I GPGVD+ P LF +E + G +Y RPVDRE SF + G +
Sbjct: 170 YYSIRGPGVDQEPR-NLFYVE-RDTGNLYCTRPVDREQYESFEI-IAFATTPDGYTPELP 226
Query: 149 LIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLIS 208
L I+I D ND+ P F E+ + T+ EN G + Q+ A D DE +T ++++ Y +I
Sbjct: 227 LPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIG 286
Query: 209 QTPLLKESGFRVDRLSGEIRL-SGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDV 265
Q P + F + +G I S LD E ++ L I+ +D L +T+T +++
Sbjct: 287 QVPP-SPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINI 345
Query: 266 QEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFD 325
+ N+H P FT+ +Y + E +LR+ V+D+D T+ WRA + IL GNE G+F
Sbjct: 346 DDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFK 405
Query: 326 ISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSV 385
I TD +TNEG+L V+KPL+YE + L I V NE + PR A ++ATV+V
Sbjct: 406 IVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPF-----SREASPRSAMSTATVTV 460
Query: 386 QVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDPANWVSV 441
V D ++ P +P V +E A GT + A DP+ S IRY+ + DP WV++
Sbjct: 461 NVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTI 520
Query: 442 DKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLR 501
D+N+G + +DRE+ + N Y I + A D G +T TGTL + L D+NDN P +
Sbjct: 521 DENTGSIKVFRSLDREAETIKNGIYNITVLASDQG--GRTCTGTLGIILQDVNDNSPFIP 578
Query: 502 PRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL 561
++ + +C+ + I A DPD PF F L+++ + W+L + L
Sbjct: 579 KKT--VIICKPTM-SSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARL 635
Query: 562 LTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPV 621
P G+Y+VP+ + D+ G+S ++ V +C C + C D +G L
Sbjct: 636 SYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKW 695
Query: 622 CAAFVALAVALLFLLRCYFVLEPKRHGCS-----VSNDEGHQTLVMYNAESKG 669
+ L +ALLF + F L G S + +D Q L++ N E+ G
Sbjct: 696 AILAILLGIALLFCI--LFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPG 746
>gi|14589891 cadherin 3, type 1 preproprotein [Homo sapiens]
Length = 829
Score = 308 bits (788), Expect = 2e-83
Identities = 242/813 (29%), Positives = 377/813 (46%), Gaps = 90/813 (11%)
Query: 32 QETDDLTKQTKEKIYQP---LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSL 88
QE L ++ KI+ LRR KR WV+ + + E GPFP+ + +L +N + +
Sbjct: 82 QERRSLKERNPLKIFPSKRILRRHKRDWVVAPISVPENGKGPFPQRLNQLKSNKDRDTKI 141
Query: 89 MYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTS 148
Y I+GPG D PE G+F++E E G + +++P+DRE + ++ V + G V+
Sbjct: 142 FYSITGPGADSPPE-GVFAVEK-ETGWLLLNKPLDREEIAKYELFGHAVSEN-GASVEDP 198
Query: 149 LIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEE-NTPNSQVLYFLI 207
+ +I ++D NDH P+F + F +V E G + Q+ A D D+ T N V Y +
Sbjct: 199 MNISIIVTDQNDHKPKFTQDTFRGSVLEGVLPGTSVMQVTATDEDDAIYTYNGVVAYSIH 258
Query: 208 SQTPL-LKESGFRVDRLSGEIR-LSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDV 265
SQ P + F + R +G I +S LD E P++TL I+A D ++T V++
Sbjct: 259 SQEPKDPHDLMFTIHRSTGTISVISSGLDREKVPEYTLTIQATDMDGDGSTTTAVAVVEI 318
Query: 266 QEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFD 325
+ N++ P F + Y+ +PE V RL V D D+P + AWRA + I+ G++ HF
Sbjct: 319 LDANDNAPMFDPQKYEAHVPENAVGHEVQRLTVTDLDAPNSPAWRATYLIMGGDDGDHFT 378
Query: 326 ISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSV 385
I+T PE+N+GIL K LD+E + +L + V NE V + ++AT+ V
Sbjct: 379 ITTHPESNQGILTTRKGLDFEAKNQHTLYVEVTNEAPFVL---------KLPTSTATIVV 429
Query: 386 QVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ---IRYELVHDPANWVSVD 442
V D N+ P F P S +V +EG G + + A DPD + I Y ++ DPA W+++D
Sbjct: 430 HVEDVNEAPVFVPPSKVVEVQEGIPTGEPVCVYTAEDPDKENQKISYRILRDPAGWLAMD 489
Query: 443 KNSGVVITVEPIDRESPH-VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLR 501
+SG V V +DRE V N+ Y +++ A+D+G PP T TGTL+L L D+ND+ P
Sbjct: 490 PDSGQVTAVGTLDREDEQFVRNNIYEVMVLAMDNGSPPTTGTGTLLLTLIDVNDHGPV-- 547
Query: 502 PRSRYMEVC-ESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRN-WGQSV 559
P R + +C +S V + L+I D DL P + PF +L + +++ W N G +V
Sbjct: 548 PEPRQITICNQSPVRQVLNI--TDKDLSPHTSPFQAQLTD---DSDIYWTAEVNEEGDTV 602
Query: 560 ELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGL-TCVELADAEVGLHVGAL 618
L + L + Y V L + D Q + +C C + TC G +
Sbjct: 603 VLSLKKFLKQDTYDVHLSLSDHGNKEQLTVIRATVCDCHGHVETCPGPWKG------GFI 656
Query: 619 FPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDV 678
PV A +AL LL LL + + D+ + Y E G Q +
Sbjct: 657 LPVLGAVLALLFLLLVLLLLVRKKRKIKEPLLLPEDDTRDNVFYYGEEGGGEEDQDYDIT 716
Query: 679 EGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHS 738
+ R E P ++ A + + + PR
Sbjct: 717 QLHRGL------------------EARPEVVLRNDVAPTIIPT----PMYRPR------- 747
Query: 739 TPAYPDATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAP 794
PA PD + + + L AN DP P+ V+ EG A
Sbjct: 748 -PANPD-------------EIGNFIIENLKAANT---DPTAPPYDTLLVFDYEGSGSDAA 790
Query: 795 SLSSLAS--LEQELQPDLLDSLGSKATPFEEIY 825
SLSSL S +Q+ D L+ GS+ ++Y
Sbjct: 791 SLSSLTSSASDQDQDYDYLNEWGSRFKKLADMY 823
>gi|4757960 cadherin 1, type 1 preproprotein [Homo sapiens]
Length = 882
Score = 307 bits (787), Expect = 2e-83
Identities = 212/641 (33%), Positives = 325/641 (50%), Gaps = 40/641 (6%)
Query: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSL 108
LRR KR WVI + E + GPFPK + ++ +N + Y I+G G D P +G+F +
Sbjct: 149 LRRQKRDWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADT-PPVGVFII 207
Query: 109 EDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEK 168
E E G + V P+DRE ++T++ V S G V+ + I ++D ND+ P+F ++
Sbjct: 208 E-RETGWLKVTEPLDRERIATYTLFSHAVS-SNGNAVEDPMEILITVTDQNDNKPEFTQE 265
Query: 169 EFNITVQENQSAGQPIFQMLAVDLDEE-NTPNSQVLYFLISQTPLLKESG-FRVDRLSGE 226
F +V E G + ++ A D D++ NT N+ + Y ++SQ P L + F ++R +G
Sbjct: 266 VFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGV 325
Query: 227 IRL-SGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
I + + LD E+ P +TL+++A D LS+T T + V + N++ P F YK Q+P
Sbjct: 326 ISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVP 385
Query: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
E A+ + L V D D+P T AW A + IL+ ++ G F ++T+P N+GIL K LD+
Sbjct: 386 ENEANVVITTLKVTDADAPNTPAWEAVYTILN-DDGGQFVVTTNPVNNDGILKTAKGLDF 444
Query: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNK 405
E + L + V N ++ATV+V V D N+ P F P V
Sbjct: 445 EAKQQYILHVAVTNVVPF---------EVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEV 495
Query: 406 EEGARPGTLLGTFNAMDPDS----QIRYELVHDPANWVSVDKNSGVVITVEPIDRES-PH 460
E G + ++ A +PD+ +I Y + D ANW+ ++ ++G + T +DRE H
Sbjct: 496 SEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEH 555
Query: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHI 520
V NS Y +I A D+G P T TGTL+L LSD+NDN P PR+ + CE +P I
Sbjct: 556 VKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFF--CERN-PKPQVI 612
Query: 521 EAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRN--WGQSVELLTLRSLPRGNYLVPLFI 578
D DL P + PFT EL + A W + N +S+ L +L G+Y + L +
Sbjct: 613 NIIDADLPPNTSPFTAELTH---GASANWTIQYNDPTQESIILKPKMALEVGDYKINLKL 669
Query: 579 GDKQGLSQKQTVHVRICPC--ASGLTCVELADAEVGLHVGALFPVCAAFVALAV----AL 632
D Q Q T+ V +C C A+G+ C + E GL + A+ + +AL + L
Sbjct: 670 MDNQNKDQVTTLEVSVCDCEGAAGV-CRKAQPVEAGLQIPAILGILGGILALLILILLLL 728
Query: 633 LFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQ 673
LFL R V EP D+ + Y+ E G Q
Sbjct: 729 LFLRRRAVVKEP----LLPPEDDTRDNVYYYDEEGGGEEDQ 765
>gi|4502719 cadherin 13 preproprotein [Homo sapiens]
Length = 713
Score = 304 bits (778), Expect = 3e-82
Identities = 188/565 (33%), Positives = 308/565 (54%), Gaps = 29/565 (5%)
Query: 48 PLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFS 107
P+ R KR V++ + + E PFP+ +G++ ++ S + ++G GVD+ P+ G+F
Sbjct: 132 PVPRQKRSIVVSPILIPENQRQPFPRDVGKVVDSDRPERS-KFRLTGKGVDQEPK-GIFR 189
Query: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
+ ++ G + V R +DRE+ + ++ + + + GK ++ + + + D ND+ P F E
Sbjct: 190 INEN-TGSVSVTRTLDREVIAVYQLFVETTDVN-GKTLEGPVPLEVIVIDQNDNRPIFRE 247
Query: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLSGE 226
+ V E G + +M A D D+ T N+ + Y + QTP F +D G+
Sbjct: 248 GPYIGHVMEGSPTGTTVMRMTAFDADDPATDNALLRYNIRQQTPDKPSPNMFYIDPEKGD 307
Query: 227 IRL---SGCLDYETA--PQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQEN 279
I LD ET P++ L+I A+D + L+ T T + + + N+H P FT++
Sbjct: 308 IVTVVSPALLDRETLENPKYELIIEAQDMAGLDVGLTGTATATIMIDDKNDHSPKFTKKE 367
Query: 280 YKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNV 339
++ + EG ++ L V+D+D P T AWRA + I++GN F+I T+P+TNEG+L+V
Sbjct: 368 FQATVEEGAVGV-IVNLTVEDKDDPTTGAWRAAYTIINGNPGQSFEIHTNPQTNEGMLSV 426
Query: 340 IKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQ 399
+KPLDYE +L+I VENE+ LV +++ATV + V D N+ P F+P
Sbjct: 427 VKPLDYEISAFHTLLIKVENEDPLV------PDVSYGPSSTATVHITVLDVNEGPVFYPD 480
Query: 400 SFIVNKEEGARPGTLLGTFNAMDPDS----QIRYELVHDPANWVSVDKNSGVVITVEPID 455
+V ++E G++L T NA DPDS IRY + DPA W++++ +G V T +D
Sbjct: 481 PMMVTRQEDLSVGSVLLTVNATDPDSLQHQTIRYSVYKDPAGWLNINPINGTVDTTAVLD 540
Query: 456 RESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVH 515
RESP V+NS Y + A+D G PP T TGTL++ L D+NDN P + P EVC+ A +
Sbjct: 541 RESPFVDNSVYTALFLAIDSGNPPATGTGTLLITLEDVNDNAPFIYPT--VAEVCDDAKN 598
Query: 516 EPLHI-EAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLV 574
+ I A D DL P +DPF FE+ + WK+ + + L++L + NY +
Sbjct: 599 LSVVILGASDKDLHPNTDPFKFEIHKQ-AVPDKVWKISKINNTHALVSLLQNLNKANYNL 657
Query: 575 PLFIGD--KQGLSQKQTVHVRICPC 597
P+ + D K ++ + V++C C
Sbjct: 658 PIMVTDSGKPPMTNITDLRVQVCSC 682
>gi|4826702 desmocollin 1 isoform Dsc1b preproprotein [Homo sapiens]
Length = 840
Score = 293 bits (750), Expect = 4e-79
Identities = 204/662 (30%), Positives = 340/662 (51%), Gaps = 40/662 (6%)
Query: 23 QVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM 82
++ ++ S ++ + TK+ L+RSKRRW L E GPFP+ + ++ ++
Sbjct: 106 EIKVVLSARENKSPKKRHTKDTA---LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA 162
Query: 83 SYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTG 142
+ N ++ Y ISGPGVD+ P LF +E + G I+ R +DRE F +Y + G
Sbjct: 163 AQNYTIFYSISGPGVDKEP-FNLFYIEK-DTGDIFCTRSIDREKYEQFALY-GYATTADG 219
Query: 143 KIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQV 202
+ L I+I D ND+AP F + TV EN +G + ++ A DLDE +T ++++
Sbjct: 220 YAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRL 279
Query: 203 LYFLISQTPLLKESGFRVDRLSGEIRLSG-CLDYETAPQFTLLIRARDCG-EP-SLSSTT 259
Y ++ Q P + F + +G I + LD E + L++ RD G +P L +T
Sbjct: 280 KYKILQQIPDHPKH-FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Query: 260 TVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGN 319
T+ + +++ N++ P+FT+ +Y ++ E R +LR+ VQD+D P T +A + IL GN
Sbjct: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
Query: 320 EEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAA 379
E G+F ISTDP TNEG+L V+KPL+YE L + V NE + F + Q P
Sbjct: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQ--FSKAASSQTP--TMC 454
Query: 380 SATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDP 435
+ TV+V++ D+++ P HP ++ ++G G L + A+DP+ +RY+ + D
Sbjct: 455 TTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDE 514
Query: 436 ANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDIND 495
NW +++++G + T++ +DRES V N+ Y I + AVD ++ TGTL++ L D ND
Sbjct: 515 DNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYND 572
Query: 496 NVPTLRPRSRYMEVCES----AVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKL 551
+ P + + + +C++ AV +P+ DPD PF F LDN +A W +
Sbjct: 573 HAPQI---DKEVTICQNNEDFAVLKPV-----DPDGPENGPPFQFFLDN---SASKNWNI 621
Query: 552 GRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTC----VELA 607
G++ L ++L Y VP+ I D+ GL + VR+C C++ C
Sbjct: 622 EEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTR 681
Query: 608 DAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAES 667
D + +G + + A + + L L C+ V + D Q L++ N E
Sbjct: 682 DVRPNVILGR-WAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEG 740
Query: 668 KG 669
G
Sbjct: 741 PG 742
>gi|13435361 desmocollin 1 isoform Dsc1a preproprotein [Homo
sapiens]
Length = 894
Score = 293 bits (750), Expect = 4e-79
Identities = 204/662 (30%), Positives = 340/662 (51%), Gaps = 40/662 (6%)
Query: 23 QVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM 82
++ ++ S ++ + TK+ L+RSKRRW L E GPFP+ + ++ ++
Sbjct: 106 EIKVVLSARENKSPKKRHTKDTA---LKRSKRRWAPIPASLMENSLGPFPQHVQQIQSDA 162
Query: 83 SYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTG 142
+ N ++ Y ISGPGVD+ P LF +E + G I+ R +DRE F +Y + G
Sbjct: 163 AQNYTIFYSISGPGVDKEP-FNLFYIEK-DTGDIFCTRSIDREKYEQFALY-GYATTADG 219
Query: 143 KIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQV 202
+ L I+I D ND+AP F + TV EN +G + ++ A DLDE +T ++++
Sbjct: 220 YAPEYPLPLIIKIEDDNDNAPYFEHRVTIFTVPENCRSGTSVGKVTATDLDEPDTLHTRL 279
Query: 203 LYFLISQTPLLKESGFRVDRLSGEIRLSG-CLDYETAPQFTLLIRARDCG-EP-SLSSTT 259
Y ++ Q P + F + +G I + LD E + L++ RD G +P L +T
Sbjct: 280 KYKILQQIPDHPKH-FSIHPDTGVITTTTPFLDREKCDTYQLIMEVRDMGGQPFGLFNTG 338
Query: 260 TVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGN 319
T+ + +++ N++ P+FT+ +Y ++ E R +LR+ VQD+D P T +A + IL GN
Sbjct: 339 TITISLEDENDNPPSFTETSYVTEVEENRIDVEILRMKVQDQDLPNTPHSKAVYKILQGN 398
Query: 320 EEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAA 379
E G+F ISTDP TNEG+L V+KPL+YE L + V NE + F + Q P
Sbjct: 399 ENGNFIISTDPNTNEGVLCVVKPLNYEVNRQVILQVGVINEAQ--FSKAASSQTP--TMC 454
Query: 380 SATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD----SQIRYELVHDP 435
+ TV+V++ D+++ P HP ++ ++G G L + A+DP+ +RY+ + D
Sbjct: 455 TTTVTVKIIDSDEGPECHPPVKVIQSQDGFPAGQELLGYKALDPEISSGEGLRYQKLGDE 514
Query: 436 ANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDIND 495
NW +++++G + T++ +DRES V N+ Y I + AVD ++ TGTL++ L D ND
Sbjct: 515 DNWFEINQHTGDLRTLKVLDRESKFVKNNQYNISVVAVD--AVGRSCTGTLVVHLDDYND 572
Query: 496 NVPTLRPRSRYMEVCES----AVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKL 551
+ P + + + +C++ AV +P+ DPD PF F LDN +A W +
Sbjct: 573 HAPQI---DKEVTICQNNEDFAVLKPV-----DPDGPENGPPFQFFLDN---SASKNWNI 621
Query: 552 GRNWGQSVELLTLRSLPRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTC----VELA 607
G++ L ++L Y VP+ I D+ GL + VR+C C++ C
Sbjct: 622 EEKDGKTAILRQRQNLDYNYYSVPIQIKDRHGLVATHMLTVRVCDCSTPSECRMKDKSTR 681
Query: 608 DAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAES 667
D + +G + + A + + L L C+ V + D Q L++ N E
Sbjct: 682 DVRPNVILGR-WAILAMVLGSVLLLCILFTCFCVTAKRTVKKCFPEDIAQQNLIVSNTEG 740
Query: 668 KG 669
G
Sbjct: 741 PG 742
>gi|148539848 desmocollin 3 isoform Dsc3b preproprotein [Homo
sapiens]
Length = 839
Score = 289 bits (739), Expect = 8e-78
Identities = 199/642 (30%), Positives = 321/642 (50%), Gaps = 32/642 (4%)
Query: 38 TKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGV 97
T+ T+E + LRR+KRRW ++E GPFP + ++ ++ + N ++ Y ISG GV
Sbjct: 122 TRHTRETV---LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGV 178
Query: 98 DEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERST--GKIVDTSLIFNIRI 155
D+ P + LF +E + G ++ RPVDRE + V+ + ST G D L IR+
Sbjct: 179 DKEP-LNLFYIE-RDTGNLFCTRPVDRE---EYDVFDLIAYASTADGYSADLPLPLPIRV 233
Query: 156 SDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKE 215
D ND+ P F E +N V E+ G + + A D DE +T ++++ Y ++ QTP +
Sbjct: 234 EDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTP--RS 291
Query: 216 SG-FRVDRLSGEIR-LSGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNH 271
G F V +G I +S LD E +++L+++ +D L T+T + V + N++
Sbjct: 292 PGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDN 351
Query: 272 RPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPE 331
P F Q Y+ + E + +LR+ ++D+D T+ WR F IL GNE GHF ISTD E
Sbjct: 352 APTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKE 411
Query: 332 TNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDAN 391
TNEG+L+V+KPL+YE +L I V NE + P A A V+V V D +
Sbjct: 412 TNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF-----ARDIPRVTALNRALVTVHVRDLD 466
Query: 392 DPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ----IRYELVHDPANWVSVDKNSGV 447
+ P P + V +E G+ + + A DP+++ +RY+ +HDP W+++D+ SG
Sbjct: 467 EGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGS 526
Query: 448 VITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYM 507
+IT + +DRE N Y I + A+D ++ TGTL + + D+NDN P + Y+
Sbjct: 527 IITSKILDREVETPKNELYNITVLAIDK--DDRSCTGTLAVNIEDVNDNPPEI--LQEYV 582
Query: 508 EVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSL 567
+C+ + I A DPD PF F L NT W L + + L ++
Sbjct: 583 VICKPKMGY-TDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
Query: 568 PRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPVCAAFVA 627
Y +P+ + D+ G + + + V +C C C G+ +G + + A +
Sbjct: 642 GFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQC-RATSRSTGVILGK-WAILAILLG 699
Query: 628 LAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKG 669
+A+ LL + G D Q L++ N E+ G
Sbjct: 700 IALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPG 741
>gi|148539846 desmocollin 3 isoform Dsc3a preproprotein [Homo
sapiens]
Length = 896
Score = 289 bits (739), Expect = 8e-78
Identities = 199/642 (30%), Positives = 321/642 (50%), Gaps = 32/642 (4%)
Query: 38 TKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGV 97
T+ T+E + LRR+KRRW ++E GPFP + ++ ++ + N ++ Y ISG GV
Sbjct: 122 TRHTRETV---LRRAKRRWAPIPCSMQENSLGPFPLFLQQVESDAAQNYTVFYSISGRGV 178
Query: 98 DEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERST--GKIVDTSLIFNIRI 155
D+ P + LF +E + G ++ RPVDRE + V+ + ST G D L IR+
Sbjct: 179 DKEP-LNLFYIE-RDTGNLFCTRPVDRE---EYDVFDLIAYASTADGYSADLPLPLPIRV 233
Query: 156 SDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKE 215
D ND+ P F E +N V E+ G + + A D DE +T ++++ Y ++ QTP +
Sbjct: 234 EDENDNHPVFTEAIYNFEVLESSRPGTTVGVVCATDRDEPDTMHTRLKYSILQQTP--RS 291
Query: 216 SG-FRVDRLSGEIR-LSGCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNH 271
G F V +G I +S LD E +++L+++ +D L T+T + V + N++
Sbjct: 292 PGLFSVHPSTGVITTVSHYLDREVVDKYSLIMKVQDMDGQFFGLIGTSTCIITVTDSNDN 351
Query: 272 RPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPE 331
P F Q Y+ + E + +LR+ ++D+D T+ WR F IL GNE GHF ISTD E
Sbjct: 352 APTFRQNAYEAFVEENAFNVEILRIPIEDKDLINTANWRVNFTILKGNENGHFKISTDKE 411
Query: 332 TNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDAN 391
TNEG+L+V+KPL+YE +L I V NE + P A A V+V V D +
Sbjct: 412 TNEGVLSVVKPLNYEENRQVNLEIGVNNEAPF-----ARDIPRVTALNRALVTVHVRDLD 466
Query: 392 DPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ----IRYELVHDPANWVSVDKNSGV 447
+ P P + V +E G+ + + A DP+++ +RY+ +HDP W+++D+ SG
Sbjct: 467 EGPECTPAAQYVRIKENLAVGSKINGYKAYDPENRNGNGLRYKKLHDPKGWITIDEISGS 526
Query: 448 VITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYM 507
+IT + +DRE N Y I + A+D ++ TGTL + + D+NDN P + Y+
Sbjct: 527 IITSKILDREVETPKNELYNITVLAIDK--DDRSCTGTLAVNIEDVNDNPPEI--LQEYV 582
Query: 508 EVCESAVHEPLHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSL 567
+C+ + I A DPD PF F L NT W L + + L ++
Sbjct: 583 VICKPKMGY-TDILAVDPDEPVHGAPFYFSLPNTSPEISRLWSLTKVNDTAARLSYQKNA 641
Query: 568 PRGNYLVPLFIGDKQGLSQKQTVHVRICPCASGLTCVELADAEVGLHVGALFPVCAAFVA 627
Y +P+ + D+ G + + + V +C C C G+ +G + + A +
Sbjct: 642 GFQEYTIPITVKDRAGQAATKLLRVNLCECTHPTQC-RATSRSTGVILGK-WAILAILLG 699
Query: 628 LAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKG 669
+A+ LL + G D Q L++ N E+ G
Sbjct: 700 IALLFSVLLTLVCGVFGATKGKRFPEDLAQQNLIISNTEAPG 741
>gi|4826669 cadherin 15 preproprotein [Homo sapiens]
Length = 814
Score = 276 bits (706), Expect = 6e-74
Identities = 232/804 (28%), Positives = 372/804 (46%), Gaps = 90/804 (11%)
Query: 49 LRRSKRRWVITTLELEEEDPG-PFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFS 107
L R +R WVI + + E P+P + ++ ++ S++Y I GPGVDE P G+FS
Sbjct: 40 LSRVRRAWVIPPISVSENHKRLPYPLV--QIKSDKQQLGSVIYSIQGPGVDEEPR-GVFS 96
Query: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
+ D G+++++ +DRE T F + ++ G ++ I + D ND+ P F +
Sbjct: 97 I-DKFTGKVFLNAMLDREKTDRFRLRAFALDLG-GSTLEDPTDLEIVVVDQNDNRPAFLQ 154
Query: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQ-TPLLKESGFRVDRLSGE 226
+ F V E G + + A D D+ T N+ + + ++ Q +P L F +D L+GE
Sbjct: 155 EAFTGRVLEGAVPGTYVTRAEATDADDPETDNAALRFSILQQGSPEL----FSIDELTGE 210
Query: 227 IR-LSGCLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
IR + LD E + L ++ D L++T + + + + N++ P FT++ + ++
Sbjct: 211 IRTVQVGLDREVVAVYNLTLQVADMSGDGLTATASAIITLDDINDNAPEFTRDEFFMEAI 270
Query: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
E + V RL V+DRD P + W A+F IL G+ +G F I TDP+TNEG+L+++K LDY
Sbjct: 271 EAVSGVDVGRLEVEDRDLPGSPNWVARFTILEGDPDGQFTIRTDPKTNEGVLSIVKALDY 330
Query: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNK 405
E+ L + V+NE L + R A V V V D N+PP F +
Sbjct: 331 ESCEHYELKVSVQNEAPL------QAAALRAERGQAKVRVHVQDTNEPPVFQENPLRTSL 384
Query: 406 EEGARPGTLLGTFNAMDPDSQ----IRYELVHDPANWVSVDKNSGVVITVEPIDRESPHV 461
EGA PGTL+ TF+A DPD++ + Y +DP +W+ VD +G + T + SP +
Sbjct: 385 AEGAPPGTLVATFSARDPDTEQLQRLSYSKDYDPEDWLQVDAATGRIQTQHVLSPASPFL 444
Query: 462 NNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIE 521
+Y I+ A DD P+TATGTL + + ++ND+ P L P E L +
Sbjct: 445 KGGWYRAIVLAQDDASQPRTATGTLSIEILEVNDHAPVLAPPPPGSLCSEPHQGPGLLLG 504
Query: 522 AEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQS------VELLTLRSLPRGNYLVP 575
A D DL P PF F+L + +LGRNW S L +P G + +
Sbjct: 505 ATDEDLPPHGAPFHFQL------SPRLPELGRNWSLSQVNVSHARLRPRHQVPEGLHRLS 558
Query: 576 LFIGD--KQGLSQKQTVHVRICPCASGLTCVELADA----EVGLHVGALFPVCA-AFVAL 628
L + D + ++Q ++V +C C C+ A A GL +GAL V A A + L
Sbjct: 559 LLLRDSGQPPQQREQPLNVTVCRCGKDGVCLPGAAALLAGGTGLSLGALVIVLASALLLL 618
Query: 629 AVALLFLLRCYFVLEPKRHG-CSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLI 687
+ LL LR F + + G D+ ++ Y+ + G Q D+ R
Sbjct: 619 VLVLLVALRARFWKQSRGKGLLHGPQDDLRDNVLNYDEQGGGEEDQDAYDISQLRHP--- 675
Query: 688 CTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATM 747
TA + P PP + Q R P PR +
Sbjct: 676 -TALSLPLG--------PPPLRRDAPQGRL--------HPQPPRVLPT------------ 706
Query: 748 HRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLASL- 802
+P++ +A+ +N L A + DP P+ +Y EG+ A +LSS+ S
Sbjct: 707 -----SPLD--IADFINDGLEAA---DSDPSVPPYDTALIYDYEGDGSVAGTLSSILSSQ 756
Query: 803 -EQELQPDLLDSLGSKATPFEEIY 825
+++ D L G + ++Y
Sbjct: 757 GDEDQDYDYLRDWGPRFARLADMY 780
>gi|197313787 desmoglein 4 isoform 1 [Homo sapiens]
Length = 1059
Score = 274 bits (700), Expect = 3e-73
Identities = 205/721 (28%), Positives = 332/721 (46%), Gaps = 62/721 (8%)
Query: 12 LLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPF 71
+ LL++L+ +++V+ V+ + D+ T + +Q +RR KR W+ E +
Sbjct: 9 ICLLIILMVVMEVNSEFIVEVKEFDIENGTTK--WQTVRRQKREWIKFAAACREGEDNSK 66
Query: 72 PKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFT 131
I ++ ++ N + Y ISG G+D P G+F++ G I + VDRE+TP F
Sbjct: 67 RNPIAKIRSDCESNQKITYRISGVGIDR-PPYGVFTINPR-TGEINITSVVDREITPLFL 124
Query: 132 VYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVD 191
+Y + S G+ ++ L +++ D+ND+AP F + + +++EN A + ++ A D
Sbjct: 125 IYCRALN-SRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATD 183
Query: 192 LDEENTPNSQVLYFLISQTPLLKESG---FRVDRLSGEI-RLSGCLDYETAPQFTLLIRA 247
DEEN NS++ Y ++SQ P SG F ++R +GE+ +S LD E + L++R
Sbjct: 184 ADEENHLNSKIAYKIVSQEP----SGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRG 239
Query: 248 --RDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPF 305
RD LSS + V + N++ P + +Y I E S ++RL D D
Sbjct: 240 SDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEG 299
Query: 306 TSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVF 365
T W A++ IL GN+ FDI TDP+TNEGIL V+K LDYE P L I V+N+ +
Sbjct: 300 TDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHY 359
Query: 366 CERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTL----LGTFNAM 421
+ Q V +QV D + PAFHP + + EG + +L LGT+ A+
Sbjct: 360 SVASQFQ-----MHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAI 414
Query: 422 D-----PDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDG 476
D P + +RY + HD +W+ +D +G + D++S ++ N Y I A+DDG
Sbjct: 415 DLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG 474
Query: 477 FPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTF 536
+TATGT+ + + DIND P + P R +C + + + + PFTF
Sbjct: 475 -SGKTATGTICIEVPDINDYCPNIFPERR--TICIDSPSVLISVNEHS-----YGSPFTF 526
Query: 537 ELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGD--KQGLSQKQTVHVRI 594
+ + D W + S L + L G Y +P+ + D + Q V +
Sbjct: 527 CVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYA 586
Query: 595 CPCASGLTCVE------------------LADAEVGLHVGALFPVCAAFVALAVALLFLL 636
C C C++ + + + G+ L P + L + LL L
Sbjct: 587 CDCDDNHMCLDSGAAGIYTEDITGDTYGPVTEDQAGVSNVGLGPAGIGMMVLGILLLILA 646
Query: 637 RCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLICTAAAGPTQ 696
+L C EG T E Q+W +EG P + +A A P
Sbjct: 647 PLLLLL----CCCKQRQPEGLGTRFAPVPEGGEGVMQSWR-IEGAHPEDRLFSAYALPGG 701
Query: 697 G 697
G
Sbjct: 702 G 702
>gi|29789445 desmoglein 4 isoform 2 [Homo sapiens]
Length = 1040
Score = 272 bits (695), Expect = 1e-72
Identities = 184/617 (29%), Positives = 301/617 (48%), Gaps = 39/617 (6%)
Query: 12 LLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPF 71
+ LL++L+ +++V+ V+ + D+ T + +Q +RR KR W+ E +
Sbjct: 9 ICLLIILMVVMEVNSEFIVEVKEFDIENGTTK--WQTVRRQKREWIKFAAACREGEDNSK 66
Query: 72 PKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFT 131
I ++ ++ N + Y ISG G+D P G+F++ G I + VDRE+TP F
Sbjct: 67 RNPIAKIRSDCESNQKITYRISGVGIDR-PPYGVFTINPR-TGEINITSVVDREITPLFL 124
Query: 132 VYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVD 191
+Y + S G+ ++ L +++ D+ND+AP F + + +++EN A + ++ A D
Sbjct: 125 IYCRALN-SRGEDLERPLELRVKVMDINDNAPVFSQSVYTASIEENSDANTLVVKLCATD 183
Query: 192 LDEENTPNSQVLYFLISQTPLLKESG---FRVDRLSGEI-RLSGCLDYETAPQFTLLIRA 247
DEEN NS++ Y ++SQ P SG F ++R +GE+ +S LD E + L++R
Sbjct: 184 ADEENHLNSKIAYKIVSQEP----SGAPMFILNRYTGEVCTMSSFLDREQHSMYNLVVRG 239
Query: 248 --RDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPF 305
RD LSS + V + N++ P + +Y I E S ++RL D D
Sbjct: 240 SDRDGAADGLSSECDCRIKVLDVNDNFPTLEKTSYSASIEENCLSSELIRLQAIDLDEEG 299
Query: 306 TSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVF 365
T W A++ IL GN+ FDI TDP+TNEGIL V+K LDYE P L I V+N+ +
Sbjct: 300 TDNWLAQYLILSGNDGNWFDIQTDPQTNEGILKVVKMLDYEQAPNIQLSIGVKNQADFHY 359
Query: 366 CERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTL----LGTFNAM 421
+ Q V +QV D + PAFHP + + EG + +L LGT+ A+
Sbjct: 360 SVASQFQ-----MHPTPVRIQVVDVREGPAFHPSTMAFSVREGIKGSSLLNYVLGTYTAI 414
Query: 422 D-----PDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDG 476
D P + +RY + HD +W+ +D +G + D++S ++ N Y I A+DDG
Sbjct: 415 DLDTGNPATDVRYIIGHDAGSWLKIDSRTGEIQFSREFDKKSKYIINGIYTAEILAIDDG 474
Query: 477 FPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTF 536
+TATGT+ + + DIND P + P R +C + + + + PFTF
Sbjct: 475 -SGKTATGTICIEVPDINDYCPNIFPERR--TICIDSPSVLISVNEHS-----YGSPFTF 526
Query: 537 ELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGD--KQGLSQKQTVHVRI 594
+ + D W + S L + L G Y +P+ + D + Q V +
Sbjct: 527 CVVDEPPGIADMWDVRSTNATSAILTAKQVLSPGFYEIPILVKDSYNRACELAQMVQLYA 586
Query: 595 CPCASGLTCVELADAEV 611
C C C++ A +
Sbjct: 587 CDCDDNHMCLDSGAAGI 603
>gi|116534898 desmoglein 2 preproprotein [Homo sapiens]
Length = 1118
Score = 239 bits (611), Expect = 6e-63
Identities = 195/661 (29%), Positives = 311/661 (47%), Gaps = 47/661 (7%)
Query: 1 MAMRSGRHPSLLLLLVLLLWLLQVSI-IDSVQQETDDLTKQTKEKIYQPLRRSKRRWVIT 59
MA GR +LLLLL+ + + + S + E L K + L R KR W+
Sbjct: 1 MARSPGRAYALLLLLICFNVGSGLHLQVLSTRNENKLLPK------HPHLVRQKRAWITA 54
Query: 60 TLELEEEDP----GPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGR 115
+ L E + P K+ +L + + Y +G G+ E P G+F + + G
Sbjct: 55 PVALREGEDLSKKNPIAKIHSDLAEERG--LKITYKYTGKGITE-PPFGIFVF-NKDTGE 110
Query: 116 IYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQ 175
+ V +DRE TP F + ++ + G V+ L I++ D+ND+ P F + F +V+
Sbjct: 111 LNVTSILDREETPFFLLTGYALD-ARGNNVEKPLELRIKVLDINDNEPVFTQDVFVGSVE 169
Query: 176 ENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEI-RLSGCLD 234
E +A + ++ A D DE NT NS++ Y ++S P F +++ +GEI S LD
Sbjct: 170 ELSAAHTLVMKINATDADEPNTLNSKISYRIVSLEPAYPPV-FYLNKDTGEIYTTSVTLD 228
Query: 235 YETAPQFTLLIRARDCGEPSLSSTTTVHVDVQ----EGNNHRPAFTQENYKVQIPEGRAS 290
E +TL + ARD G ++ VQ + N++ P + + + E + +
Sbjct: 229 REEHSSYTLTVEARD-GNGEVTDKPVKQAQVQIRILDVNDNIPVVENKVLEGMVEENQVN 287
Query: 291 QGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPA 350
V R+ V D D + W A F GNE G+F I TD +TNEGI+ +IK +DYE
Sbjct: 288 VEVTRIKVFDADEIGSDNWLANFTFASGNEGGYFHIETDAQTNEGIVTLIKEVDYEEMKN 347
Query: 351 QSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVN-----K 405
++V N+ R K +P + ++V N H +S +++
Sbjct: 348 LDFSVIVANKAAFHKSIRSKYKP-------TPIPIKVKVKNVKEGIHFKSSVISIYVSES 400
Query: 406 EEGARPGTLLGTFNAMDPDSQI----RYELVHDPANWVSVDKNSGVVITVEPIDRESPHV 461
+ + G ++G F A D D+ + RY + D NW+SVD + + + D ES +V
Sbjct: 401 MDRSSKGQIIGNFQAFDEDTGLPAHARYVKLEDRDNWISVDSVTSEIKLAKLPDFESRYV 460
Query: 462 NNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIE 521
N Y + I A+ + +P +T TGT+++ + DINDN PTL +C A E +++
Sbjct: 461 QNGTYTVKIVAISEDYPRKTITGTVLINVEDINDNCPTL--IEPVQTICHDA--EYVNVT 516
Query: 522 AEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDK 581
AED D P S PF+F + + + WK+ R SV LL G + I D
Sbjct: 517 AEDLDGHPNSGPFSFSVIDKPPGMAEKWKIARQESTSV-LLQQSEKKLGRSEIQFLISDN 575
Query: 582 QGLS--QKQTVHVRICPCASGLTCVELA-DAEVGLHVGALFPVCAAFVALAVALLFLLRC 638
QG S +KQ + + +C C G C E D+ VGL A+ + AF+ L + L LL C
Sbjct: 576 QGFSCPEKQVLTLTVCECLHGSGCREAQHDSYVGLGPAAIALMILAFLLLLLVPLLLLMC 635
Query: 639 Y 639
+
Sbjct: 636 H 636
>gi|119964718 desmoglein 3 preproprotein [Homo sapiens]
Length = 999
Score = 229 bits (584), Expect = 8e-60
Identities = 179/644 (27%), Positives = 298/644 (46%), Gaps = 39/644 (6%)
Query: 10 SLLLLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPG 69
+L + +V++L ++ I Q + +++T Q Q RR KR WV E +
Sbjct: 11 ALAIFVVVILVHGELRIETKGQYDEEEMTMQ------QAKRRQKREWVKFAKPCREGEDN 64
Query: 70 PFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPS 129
I ++ ++ + Y ISG G+D+ P G+F + D G I + VDRE TPS
Sbjct: 65 SKRNPIAKITSDYQATQKITYRISGVGIDQ-PPFGIFVV-DKNTGDINITAIVDREETPS 122
Query: 130 FTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLA 189
F + + + G V+ LI ++I D+ND+ P F ++ F ++EN ++ + + A
Sbjct: 123 FLITCRALN-AQGLDVEKPLILTVKILDINDNPPVFSQQIFMGEIEENSASNSLVMILNA 181
Query: 190 VDLDEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIR-LSGCLDYETAPQFTLLIRAR 248
D DE N NS++ + ++SQ P F + R +GE+R L+ LD E A + L++
Sbjct: 182 TDADEPNHLNSKIAFKIVSQEPAGTPM-FLLSRNTGEVRTLTNSLDREQASSYRLVVSGA 240
Query: 249 DCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSA 308
D LS+ ++ V++ N++ P F Y +I E S +LR V D D +T
Sbjct: 241 DKDGEGLSTQCECNIKVKDVNDNFPMFRDSQYSARIEENILSSELLRFQVTDLDEEYTDN 300
Query: 309 WRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCER 368
W A + GNE F+I TDP TNEGIL V+K LDYE + L I V+N+ E
Sbjct: 301 WLAVYFFTSGNEGNWFEIQTDPRTNEGILKVVKALDYEQLQSVKLSIAVKNK-----AEF 355
Query: 369 GKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTL----LGTFNAMDPD 424
+ R S V++QV + + AF P S ++G L LGT+ A+D D
Sbjct: 356 HQSVISRYRVQSTPVTIQVINVREGIAFRPASKTFTVQKGISSKKLVDYILGTYQAIDED 415
Query: 425 -----SQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPP 479
S ++Y + + ++ +D + + V+ ++R+S + N + A+D+ +
Sbjct: 416 TNKAASNVKYVMGRNDGGYLMIDSKTAEIKFVKNMNRDSTFIVNKTITAEVLAIDE-YTG 474
Query: 480 QTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPLHIEAEDPDLEPFSDPFTFELD 539
+T+TGT+ + + D NDN PT VC S+ P + + ++ P+TF L+
Sbjct: 475 KTSTGTVYVRVPDFNDNCPTAVLEKD--AVCSSS---PSVVVSARTLNNRYTGPYTFALE 529
Query: 540 NTWGNAEDTWKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDKQG--LSQKQTVHVRICPC 597
+ W + S L +P G Y + L + D Q +++ + +C C
Sbjct: 530 DQPVKLPAVWSITTLNATSALLRAQEQIPPGVYHISLVLTDSQNNRCEMPRSLTLEVCQC 589
Query: 598 AS-GLTCVELADAEVGL-----HVGALFPVCAAFVALAVALLFL 635
+ G+ G H G L P + L + LL L
Sbjct: 590 DNRGICGTSYPTTSPGTRYGRPHSGRLGPAAIGLLLLGLLLLLL 633
>gi|4826671 cadherin 18, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 219 bits (559), Expect = 6e-57
Identities = 215/806 (26%), Positives = 364/806 (45%), Gaps = 101/806 (12%)
Query: 51 RSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGLFSLE 109
R KR WV + EE GP P+ +G+L +N + S+ Y+++G G G +
Sbjct: 50 RPKRGWVWNQFFVLEEHMGPDPQYVGKLHSNSDKGDGSVKYILTGEGA------GTIFII 103
Query: 110 DHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKE 169
D G I+ + +DRE + ++ ++R T K ++ F I++ D+ND+AP+F +
Sbjct: 104 DDTTGDIHSTKSLDREQKTHYVLHAQAIDRRTNKPLEPESEFIIKVQDINDNAPKFTDGP 163
Query: 170 FNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGEIR 228
+ +TV E G + Q+ A D D+ NS +V+Y ++ P F VD +G IR
Sbjct: 164 YIVTVPEMSDMGTSVLQVTATDADDPTYGNSARVVYSILQGQPY-----FSVDPKTGVIR 218
Query: 229 LS-GCLDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
+ +D E ++++I+A+D LS +TTV++ + + N++ P F Q++Y++ +P
Sbjct: 219 TALHNMDREAREHYSVVIQAKDMAGQVGGLSGSTTVNITLTDVNDNPPRFPQKHYQLYVP 278
Query: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
E A G ++ D+ S ++I++G+ G F ISTD ET EGIL++ KPL+Y
Sbjct: 279 ES-AQVGSAVGKIKANDADTGSNADMTYSIINGDGMGIFSISTDKETREGILSLKKPLNY 337
Query: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNK 405
E + +S + +E + L P + A + + V D ++PP F S+++
Sbjct: 338 EKK--KSYTLNIEGANTHLDFRFSHLGPFKDA---TMLKIIVGDVDEPPLFSMPSYLMEV 392
Query: 406 EEGARPGTLLGTFNAMDPDSQ---IRYELVH--DPANWVSVDKNSGVVITVEPIDRESPH 460
E A+ GT++GT A DPDS +RY + + + + ++D N+G + T + +DRE
Sbjct: 393 YENAKIGTVVGTVLAQDPDSTNSLVRYFINYNVEDDRFFNIDANTGTIRTTKVLDRE--- 449
Query: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCE-SAVHEPLH 519
+Y I + A + P + T+ + + D+NDN P L R + VCE S + +H
Sbjct: 450 -ETPWYNITVTASEIDNPDLLSHVTVGIRVLDVNDNPPEL-AREYDIIVCENSKPGQVIH 507
Query: 520 -IEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLR----SLPRGNYLV 574
I A D D F F LD + L N + +LT R + Y +
Sbjct: 508 TISATDKDDFANGPRFNFFLDERL-PVNPNFTLKDNEDNTASILTRRRRFSRTVQDVYYL 566
Query: 575 PLFIGDK--QGLSQKQTVHVRICPCASG---LTC-VELADAEVGLHVGALFPV-CAAFVA 627
P+ I D LS T+ +R+C C TC E + GL GAL + +
Sbjct: 567 PIMISDGGIPSLSSSSTLTIRVCACERDGRVRTCHAEAFLSSAGLSTGALIAILLCVLIL 626
Query: 628 LAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPALLI 687
LA+ +LF+ + K+ +S ++ + +V Y+ E G D+ R
Sbjct: 627 LAIVVLFIT----LRRSKKEPLIISEEDVRENVVTYDDEGGGEEDTEAFDITALR----- 677
Query: 688 CTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDATM 747
PSAA + Y + P + TP + ++
Sbjct: 678 -----------------NPSAAEELK----------YRRDIRP----EVKLTPRHQTSST 706
Query: 748 HRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSLASLE 803
+ + E + Q+L A++ DP P+ Y+ EG+ A S+SSL S
Sbjct: 707 LESI------DVQEFIKQRLAEADL---DPSVPPYDSLQTYAYEGQRSEAGSISSLDSAT 757
Query: 804 QELQPD--LLDSLGSKATPFEEIYSE 827
+ D L G + E+Y E
Sbjct: 758 TQSDQDYHYLGDWGPEFKKLAELYGE 783
>gi|16306537 cadherin 20, type 2 preproprotein [Homo sapiens]
Length = 801
Score = 219 bits (559), Expect = 6e-57
Identities = 223/821 (27%), Positives = 362/821 (44%), Gaps = 109/821 (13%)
Query: 47 QPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGL 105
Q +R+KR WV + EE G P +G+L ++M + S+ Y++SG G G+
Sbjct: 52 QSHQRTKRSWVWNQFFVLEEYTGTDPLYVGKLHSDMDRGDGSIKYILSGEGA------GI 105
Query: 106 FSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQF 165
D G I+ + +DRE +T+ ++R TG+ ++ F I+I D+ND+ P+F
Sbjct: 106 VFTIDDTTGDIHAIQRLDREERAQYTLRAQALDRRTGRPMEPESEFIIKIQDINDNEPKF 165
Query: 166 PEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLS 224
+ + TV E G + Q+ A D D+ NS +V+Y ++ P F VD +
Sbjct: 166 LDGPYVATVPEMSPVGTSVIQVTATDADDPTYGNSARVVYSILQGQPY-----FSVDSKT 220
Query: 225 GEIRLSGC-LDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYK 281
G IR + +D E + ++I+A+D G L+ TTTV++ + + N++ P F Q++Y+
Sbjct: 221 GVIRTALMNMDREAKEYYEVIIQAKDMGGQLGGLAGTTTVNITLSDVNDNPPRFPQKHYQ 280
Query: 282 VQIPEGR-ASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVI 340
+ + E S V R+ +D D + K+ I+ G+ FDISTDP GI+ V
Sbjct: 281 MSVLESAPISSTVGRVFAKDLDEGINA--EMKYTIVDGDGADAFDISTDPNFQVGIITVK 338
Query: 341 KPLDYETRPAQSLIIVVENEE-RLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQ 399
KPL +E++ + +L + N + F G Q + TV + V D ++PP F P
Sbjct: 339 KPLSFESKKSYTLKVEGANPHLEMRFLNLGPFQD------TTTVHISVEDVDEPPVFEPG 392
Query: 400 SFIVNKEEGARPGTLLGTFNAMDPD---SQIRYEL--VHDPANWVSVDKNSGVVITVEPI 454
+ V E GT + +A DPD + IRY + DP + VD +G ++T P+
Sbjct: 393 FYFVEVPEDVAIGTTIQIISAKDPDVTNNSIRYSIDRSSDPGRFFYVDITTGALMTARPL 452
Query: 455 DRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAV 514
DRE S++ I + A++ P Q + + + + D+NDN P PR VCE+A
Sbjct: 453 DRE----EFSWHNITVLAMEMNNPSQVGSVPVTIKVLDVNDNAPEF-PRFYEAFVCENAK 507
Query: 515 HEPL--HIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRS----LP 568
L + A D D F + L N + + N + +LT RS
Sbjct: 508 AGQLIQTVSAVDQDDPRNGQHFYYSLAPEAAN-NPNFTIRDNQDNTARILTRRSGFRQQE 566
Query: 569 RGNYLVPLFIGD--KQGLSQKQTVHVRICPCASG---LTC-VELADAEVGLHVGALFPVC 622
+ + +P+ I D + LS T+ +++C C ++C E V L GAL +
Sbjct: 567 QSVFHLPILIADSGQPVLSSTGTLTIQVCSCDDDGHVMSCSPEAYMLPVSLSRGALIAIL 626
Query: 623 AAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEG-HQTLVMYNAESKGTS-------AQT 674
A L V +L +L + ++ + ++E H+ +V Y+ E G A
Sbjct: 627 ACIFVLLVLVLLILS---MRRHRKQPYIIDDEENIHENIVRYDDEGGGEEDTEAFDIAAM 683
Query: 675 WSDVEGQRPALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVK 734
W+ E Q A A P L E+ + S+ CA+ S
Sbjct: 684 WNPREAQ--------AGAAPKTRQDMLPEI--ESLSRYVPQTCAVNS------------- 720
Query: 735 NIHSTPAYPDATMHRQLLAPVEGRMAETLNQKLHVANV-LEDDPGYLPHVYSEEGECGGA 793
T+H +LA KL+ A++ L P Y EG+ A
Sbjct: 721 -----------TVHSYVLA------------KLYEADMDLWAPPFDSLQTYMFEGDGSVA 757
Query: 794 PSLSSL--ASLEQELQPDLLDSLGSKATPFEEIYSESGVPS 832
SLSSL A+ + E D L G + E+Y S P+
Sbjct: 758 GSLSSLQSATSDSEQSFDFLTDWGPRFRKLAELYGASEGPA 798
>gi|166362713 cadherin 5, type 2 preproprotein [Homo sapiens]
Length = 784
Score = 212 bits (539), Expect = 1e-54
Identities = 225/803 (28%), Positives = 353/803 (43%), Gaps = 98/803 (12%)
Query: 50 RRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLE 109
RR KR W+ + ++EE P +G++ +++S + YL+ G EY +G
Sbjct: 43 RRQKRDWIWNQMHIDEEKNTSLPHHVGKIKSSVS-RKNAKYLLKG----EY--VGKVFRV 95
Query: 110 DHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKE 169
D E G ++ +DRE + + +V++ TG+ ++T F I++ DVND+ P F +
Sbjct: 96 DAETGDVFAIERLDRENISEYHLTAVIVDKDTGENLETPSSFTIKVHDVNDNWPVFTHRL 155
Query: 170 FNITVQENQSAGQPIFQMLAVDLDEENT-PNSQVLYFLISQTPLLKESGFRVDRLSGEIR 228
FN +V E+ + G + + AVD D+ ++ V+Y + L + F +D I
Sbjct: 156 FNASVPESSAVGTSVISVTAVDADDPTVGDHASVMYQI-----LKGKEYFAIDNSGRIIT 210
Query: 229 LSGCLDYETAPQFTLLIRARDC-GEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEG 287
++ LD E ++ +++ ARD G S T TV V +Q+ N++ P FTQ Y +PE
Sbjct: 211 ITKSLDREKQARYEIVVEARDAQGLRGDSGTATVLVTLQDINDNFPFFTQTKYTFVVPED 270
Query: 288 -RASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYE 346
R V L V+D D P K++IL G+ + F I T+P NEGI+ +KPLDYE
Sbjct: 271 TRVGTSVGSLFVEDPDEPQNR--MTKYSILRGDYQDAFTIETNPAHNEGIIKPMKPLDYE 328
Query: 347 TRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAF-HPQSFIVNK 405
Q +VE + + + + PP A A V + +TD ++PP F P K
Sbjct: 329 Y--IQQYSFIVEATDPTI--DLRYMSPP--AGNRAQVIINITDVDEPPIFQQPFYHFQLK 382
Query: 406 EEGARPGTLLGTFNAMDPDS---QIRYEL--VHDPANWVSVDKNSGVVITVEPIDRESPH 460
E +P L+GT AMDPD+ I Y + D + V K G + + +DRE
Sbjct: 383 ENQKKP--LIGTVLAMDPDAARHSIGYSIRRTSDKGQFFRVTK-KGDIYNEKELDREV-- 437
Query: 461 VNNSFYVIIIHA--VDDGFPPQTATGTLMLFLS--DINDNVPTLRPRSRYMEVCESAVHE 516
+Y + + A +D P + + + D NDN P + +VCE+AVH
Sbjct: 438 --YPWYNLTVEAKELDSTGTPTGKESIVQVHIEVLDENDNAPEF-AKPYQPKVCENAVHG 494
Query: 517 P--LHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL-LTLRSLPRGN-- 571
L I A D D+ P + F F L N E+ + L N + + + R +
Sbjct: 495 QLVLQISAIDKDITPRNVKFKFIL-----NTENNFTLTDNHDNTANITVKYGQFDREHTK 549
Query: 572 -YLVPLFIGDKQGLSQ--KQTVHVRICPC--ASGLTCVELADAEVGLHVGALFPVCAAFV 626
+ +P+ I D S+ T+ V +C C T E A+VG+ + A+ + +
Sbjct: 550 VHFLPVVISDNGMPSRTGTSTLTVAVCKCNEQGEFTFCEDMAAQVGVSIQAVVAILLCIL 609
Query: 627 ALAV-ALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKGTSAQTWSDVEGQRPAL 685
+ V LL LR + + HG SV E H+ LV Y+ E G T DV
Sbjct: 610 TITVITLLIFLRRRLRKQARAHGKSV--PEIHEQLVTYDEEGGGEMDTTSYDVS------ 661
Query: 686 LICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYPDA 745
++ + G + + + PS +Q KP PR H P
Sbjct: 662 VLNSVRRGGAKPPRPALDARPSLYAQ------------VQKP--PRHAPGAHGGP----- 702
Query: 746 TMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGY-LPHVYSEEGECGGAPSLSSLA--SL 802
G MA + K A+ D P Y H+Y EG A SLSSL S
Sbjct: 703 -----------GEMAAMIEVKKDEADHDGDGPPYDTLHIYGYEGSESIAESLSSLGTDSS 751
Query: 803 EQELQPDLLDSLGSKATPFEEIY 825
+ ++ D L+ G + E+Y
Sbjct: 752 DSDVDYDFLNDWGPRFKMLAELY 774
>gi|16306487 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 212 bits (539), Expect = 1e-54
Identities = 178/625 (28%), Positives = 296/625 (47%), Gaps = 48/625 (7%)
Query: 36 DLTKQTKEKIYQPLR-RSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLIS 93
+L++ + +Q R R+KR WV + EE G P +G+L +++ + S+ Y++S
Sbjct: 28 ELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILS 87
Query: 94 GPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNI 153
G G + D G I+ + +DRE +T+ ++R T K V+ F I
Sbjct: 88 GEGASS------IFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVI 141
Query: 154 RISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPL 212
+I D+ND+ P+F + + V E G + Q+ A D D+ NS +V+Y ++ P
Sbjct: 142 KIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPY 201
Query: 213 LKESGFRVDRLSGEIRLS-GCLDYETAPQFTLLIRARDC--GEPSLSSTTTVHVDVQEGN 269
F V+ +G I+ + +D E Q+ L+I+A+D LS TT+V V + + N
Sbjct: 202 -----FSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVN 256
Query: 270 NHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTD 329
++ P F + +Y+ +PE V+ ++ D+ + ++ I+ G+ G F IS D
Sbjct: 257 DNPPRFPRRSYQYNVPESLPVASVV-ARIKAADADIGANAEMEYKIVDGDGLGIFKISVD 315
Query: 330 PETNEGILNVIKPLDYETRPAQSLIIVVENEER-LVFCERGKLQPPRKAAASATVSVQVT 388
ET EGI+ + K LD+E + + +L I N++ F G + + TV + V
Sbjct: 316 KETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPF------SDTTTVKIIVE 369
Query: 389 DANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ---IRYELVH--DPANWVSVDK 443
D ++PP F + + E + G ++GT A DPDS +RY + D + ++D
Sbjct: 370 DVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDA 429
Query: 444 NSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPR 503
NSGV+ T + +DRE+ N+ + I + A++ P Q G + + + DINDN P
Sbjct: 430 NSGVITTAKSLDRET----NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEF-AM 484
Query: 504 SRYMEVCESAVHEPL--HIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL 561
VCE+A + I A D D F F L T + L N + +
Sbjct: 485 DYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSL-TTDATNNHNFSLKDNKDNTASI 543
Query: 562 LT----LRSLPRGNYLVPLFIGD--KQGLSQKQTVHVRICPC-ASGLTCVELADAEV--- 611
LT R + Y +P+FI D LS T+ +R+C C A G+ A+A V
Sbjct: 544 LTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPA 603
Query: 612 GLHVGALFPVCAAFVALAVALLFLL 636
GL GAL + A + L V +L ++
Sbjct: 604 GLSTGALIAILACVLTLLVLILLIV 628
>gi|16306489 cadherin 7, type 2 preproprotein [Homo sapiens]
Length = 785
Score = 212 bits (539), Expect = 1e-54
Identities = 178/625 (28%), Positives = 296/625 (47%), Gaps = 48/625 (7%)
Query: 36 DLTKQTKEKIYQPLR-RSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLIS 93
+L++ + +Q R R+KR WV + EE G P +G+L +++ + S+ Y++S
Sbjct: 28 ELSRSRSKPYFQSGRSRTKRSWVWNQFFVLEEYMGSDPLYVGKLHSDVDKGDGSIKYILS 87
Query: 94 GPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNI 153
G G + D G I+ + +DRE +T+ ++R T K V+ F I
Sbjct: 88 GEGASS------IFIIDENTGDIHATKRLDREEQAYYTLRAQALDRLTNKPVEPESEFVI 141
Query: 154 RISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPL 212
+I D+ND+ P+F + + V E G + Q+ A D D+ NS +V+Y ++ P
Sbjct: 142 KIQDINDNEPKFLDGPYTAGVPEMSPVGTSVVQVTATDADDPTYGNSARVVYSILQGQPY 201
Query: 213 LKESGFRVDRLSGEIRLS-GCLDYETAPQFTLLIRARDC--GEPSLSSTTTVHVDVQEGN 269
F V+ +G I+ + +D E Q+ L+I+A+D LS TT+V V + + N
Sbjct: 202 -----FSVEPKTGVIKTALPNMDREAKDQYLLVIQAKDMVGQNGGLSGTTSVTVTLTDVN 256
Query: 270 NHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTD 329
++ P F + +Y+ +PE V+ ++ D+ + ++ I+ G+ G F IS D
Sbjct: 257 DNPPRFPRRSYQYNVPESLPVASVV-ARIKAADADIGANAEMEYKIVDGDGLGIFKISVD 315
Query: 330 PETNEGILNVIKPLDYETRPAQSLIIVVENEER-LVFCERGKLQPPRKAAASATVSVQVT 388
ET EGI+ + K LD+E + + +L I N++ F G + + TV + V
Sbjct: 316 KETQEGIITIQKELDFEAKTSYTLRIEAANKDADPRFLSLGPF------SDTTTVKIIVE 369
Query: 389 DANDPPAFHPQSFIVNKEEGARPGTLLGTFNAMDPDSQ---IRYELVH--DPANWVSVDK 443
D ++PP F + + E + G ++GT A DPDS +RY + D + ++D
Sbjct: 370 DVDEPPVFSSPLYPMEVSEATQVGNIIGTVAAHDPDSSNSPVRYSIDRNTDLERYFNIDA 429
Query: 444 NSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPR 503
NSGV+ T + +DRE+ N+ + I + A++ P Q G + + + DINDN P
Sbjct: 430 NSGVITTAKSLDRET----NAIHNITVLAMESQNPSQVGRGYVAITILDINDNAPEF-AM 484
Query: 504 SRYMEVCESAVHEPL--HIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVEL 561
VCE+A + I A D D F F L T + L N + +
Sbjct: 485 DYETTVCENAQPGQVIQKISAVDKDEPSNGHQFYFSL-TTDATNNHNFSLKDNKDNTASI 543
Query: 562 LT----LRSLPRGNYLVPLFIGD--KQGLSQKQTVHVRICPC-ASGLTCVELADAEV--- 611
LT R + Y +P+FI D LS T+ +R+C C A G+ A+A V
Sbjct: 544 LTRRNGFRRQEQSVYYLPIFIVDSGSPSLSSTNTLTIRVCDCDADGVAQTCNAEAYVLPA 603
Query: 612 GLHVGALFPVCAAFVALAVALLFLL 636
GL GAL + A + L V +L ++
Sbjct: 604 GLSTGALIAILACVLTLLVLILLIV 628
>gi|32880203 cadherin-like 24 isoform 2 [Homo sapiens]
Length = 781
Score = 206 bits (525), Expect = 6e-53
Identities = 226/782 (28%), Positives = 349/782 (44%), Gaps = 104/782 (13%)
Query: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSYNMS-LMYLISGPGVDEYPEIGLFS 107
L R++R WV + EE GP P LIG+L +++ YL++G G G
Sbjct: 39 LLRTRRSWVWNQFFVIEEYAGPEPVLIGKLHSDVDRGEGRTKYLLTGEGA------GTVF 92
Query: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
+ D G I+V + +DRE + + V+R++ + ++ F I++ D+ND+ P FP
Sbjct: 93 VIDEATGNIHVTKSLDREEKAQYVLLAQAVDRASNRPLEPPSEFIIKVQDINDNPPIFPL 152
Query: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGE 226
++ TV E + G + Q+ A D D+ + NS +++Y ++ P F VD +G
Sbjct: 153 GPYHATVPEMSNVGTSVIQVTAHDADDPSYGNSAKLVYTVLDGLPF-----FSVDPQTGV 207
Query: 227 IRLS-GCLDYETAPQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQ 283
+R + +D ET +F ++I+A+D G LS +TTV V + + N++ P F Q Y+
Sbjct: 208 VRTAIPNMDRETQEEFLVVIQAKDMGGHMGGLSGSTTVTVTLSDVNDNPPKFPQSLYQFS 267
Query: 284 IPEGRASQGVL--RLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIK 341
+ E A G L RL QD D + ++IL G F ISTD + +G+L V K
Sbjct: 268 VVE-TAGPGTLVGRLRAQDPDLGDNAL--MAYSILDGEGSEAFSISTDLQGRDGLLTVRK 324
Query: 342 PLDYETRPAQSLIIVVENE-ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQS 400
PLD+E++ + S + N + RG P K AS V+VQ DA +PPAF +
Sbjct: 325 PLDFESQRSYSFRVEATNTLIDPAYLRRG----PFKDVASVRVAVQ--DAPEPPAFTQAA 378
Query: 401 FIVNKEEGARPGTLLGTFNAMD---PDSQIRYELV--HDPANWVSVDKNSGVVITVEPID 455
+ + E PGTL+G +A D P S IRY ++ DP S+ G + T P+D
Sbjct: 379 YHLTVPENKAPGTLVGQISAADLDSPASPIRYSILPHSDPERCFSIQPEEGTIHTAAPLD 438
Query: 456 RESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTL-RPRSRYMEVCESAV 514
RE+ +++ + + A + Q + + + D NDN P L P + VC+SA
Sbjct: 439 REA----RAWHNLTVLATELDSSAQASRVQVAIQTLDENDNAPQLAEPYDTF--VCDSAA 492
Query: 515 HEPL--HIEAEDPDLEPFSDPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRSLPR-GN 571
L I A D D S +F+ +A T + R+ S+ L + + PR
Sbjct: 493 PGQLIQVIRALDRDEVGNSSHVSFQ-GPLGPDANFTVQDNRDGSASLLLPSRPAPPRHAP 551
Query: 572 YLVPLFIGD--KQGLSQKQTVHVRICPC---ASGLTC-VELADAEVGLHVGALFPVCAAF 625
YLVP+ + D + LS TV V +C C S +C E + GL GAL +
Sbjct: 552 YLVPIELWDWGQPALSSTATVTVSVCRCQPDGSVASCWPEAHLSAAGLSTGALLAIITCV 611
Query: 626 VA-LAVALLFLLRCYFVLEPKRHGCSVSNDEG-HQTLVMYNAESKGTSAQTWSDVEGQRP 683
A LA+ +LF+ + K+ V +E + ++ Y+ E G D+
Sbjct: 612 GALLALVVLFVA----LRRQKQEALMVLEEEDVRENIITYDDEGGGEEDTEAFDI----T 663
Query: 684 ALLICTAAAGPTQGVKDLEEVPPSAASQSAQARCALGSWGYGKPFEPRSVKNIHSTPAYP 743
AL AA P G PP+ P
Sbjct: 664 ALQNPDGAAPPAPG-------PPARRD------------------------------VLP 686
Query: 744 DATMHRQLLAPVEGRMAETLNQKLHVANVLEDDPGYLPH----VYSEEGECGGAPSLSSL 799
A + RQ P +A+ L +L A ++DPG P+ VY EG SLSSL
Sbjct: 687 RARVSRQPRPPGPADVAQLLALRLREA---DEDPGVPPYDSVQVYGYEGRGSSCGSLSSL 743
Query: 800 AS 801
S
Sbjct: 744 GS 745
>gi|221316595 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 206 bits (523), Expect = 9e-53
Identities = 159/545 (29%), Positives = 256/545 (46%), Gaps = 35/545 (6%)
Query: 106 FSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQF 165
FS++ + G IYV +P+DRE ++ V++ V + GK + L ++++ D+ND+ P
Sbjct: 284 FSID--QEGDIYVTQPLDREEKDAY-VFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTC 340
Query: 166 PEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLS 224
P VQEN+ G I + A D DEENT NS + Y ++ QTP L G F + +
Sbjct: 341 PSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYA 400
Query: 225 GEIRLSG-CLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYK-- 281
G ++L+ L + PQ+ L I D + V ++V + N+ P F + +Y
Sbjct: 401 GMLQLAKQSLKKQDTPQYNLTIEVSD---KDFKTLCFVQINVIDINDQIPIFEKSDYGNL 457
Query: 282 VQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIK 341
+ +L + D D PFT + + ++I+ G+ EG + TDP TN G + + K
Sbjct: 458 TLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKK 517
Query: 342 PLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSF 401
PLD+ET +++ EN E LVF + A++ A ++ VTD N+ P F F
Sbjct: 518 PLDFETAAVSNIVFKAENPEPLVFGVK------YNASSFAKFTLIVTDVNEAPQFSQHVF 571
Query: 402 IVNKEEGARPGTLLGTFNAMDPDS-QIRYELVHDPANWVSVDKNSGVVITVEPIDRESPH 460
E GT +G A DP+ I Y L D W+ +D +G + +V P+DRE+
Sbjct: 572 QAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREA-- 629
Query: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCES-AVHEPLH 519
S Y + + A + G ++ L L D+NDN P L + C + L
Sbjct: 630 --GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLI 687
Query: 520 IEAEDPDLEPFSDP-FTFELDNTWGNAEDTWKLGRNWGQSVELLTLRS-LPRGNYLVPLF 577
EA D D F P FTF L + G+ ++ W++ + G L T + Y+V +
Sbjct: 688 FEATDDDQHLFRGPHFTFSLGS--GSLQNDWEVSKINGTHARLSTRHTEFEEREYVVLIR 745
Query: 578 IGD--KQGLSQKQTVHVRICPCASGLTCVELADAE-----VGLHVGALFPVCAAFVALAV 630
I D + L ++ V C C G +C A + VG+ VG L + + +
Sbjct: 746 INDGGRPPLEGIVSLPVTFCSCVEG-SCFRPAGHQTGIPTVGMAVGILLTTLLV-IGIIL 803
Query: 631 ALLFL 635
A++F+
Sbjct: 804 AVVFI 808
Score = 96.3 bits (238), Expect = 1e-19
Identities = 83/322 (25%), Positives = 146/322 (45%), Gaps = 36/322 (11%)
Query: 114 GRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNIT 173
G +Y +R +DRE + + ++ + G IV+ + I++ D+ND+ P F + ++ +
Sbjct: 76 GLLYYNRALDRETRSTHNLQVAALD-ANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGS 134
Query: 174 VQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKE-SGFRVDRLSGEIRLS-- 230
V++N G+P + A DLD+ TPN Q+ Y ++ Q P++ F+++ +G I L+
Sbjct: 135 VRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTRE 194
Query: 231 GCLDYETA--PQFTLLIRARDCG---EPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
G + A P + L+I +D G E S S TT+V + V E P V++
Sbjct: 195 GSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPK------PVEMV 248
Query: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
E +++ + P A+++++ + F S D EG + V +PLD
Sbjct: 249 ENSTDPHPIKITQVRWNDP-----GAQYSLVDKEKLPRFPFSID---QEGDIYVTQPLDR 300
Query: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIV-N 404
E + A V ++E + + + V+V D ND P P V
Sbjct: 301 EEKDAYVFYAVAKDEY------------GKPLSYPLEIHVKVKDINDNPPTCPSPVTVFE 348
Query: 405 KEEGARPGTLLGTFNAMDPDSQ 426
+E R G +GT A D D +
Sbjct: 349 VQENERLGNSIGTLTAHDRDEE 370
>gi|221316593 cadherin 17 precursor [Homo sapiens]
Length = 832
Score = 206 bits (523), Expect = 9e-53
Identities = 159/545 (29%), Positives = 256/545 (46%), Gaps = 35/545 (6%)
Query: 106 FSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQF 165
FS++ + G IYV +P+DRE ++ V++ V + GK + L ++++ D+ND+ P
Sbjct: 284 FSID--QEGDIYVTQPLDREEKDAY-VFYAVAKDEYGKPLSYPLEIHVKVKDINDNPPTC 340
Query: 166 PEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESG-FRVDRLS 224
P VQEN+ G I + A D DEENT NS + Y ++ QTP L G F + +
Sbjct: 341 PSPVTVFEVQENERLGNSIGTLTAHDRDEENTANSFLNYRIVEQTPKLPMDGLFLIQTYA 400
Query: 225 GEIRLSG-CLDYETAPQFTLLIRARDCGEPSLSSTTTVHVDVQEGNNHRPAFTQENYK-- 281
G ++L+ L + PQ+ L I D + V ++V + N+ P F + +Y
Sbjct: 401 GMLQLAKQSLKKQDTPQYNLTIEVSD---KDFKTLCFVQINVIDINDQIPIFEKSDYGNL 457
Query: 282 VQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIK 341
+ +L + D D PFT + + ++I+ G+ EG + TDP TN G + + K
Sbjct: 458 TLAEDTNIGSTILTIQATDADEPFTGSSKILYHIIKGDSEGRLGVDTDPHTNTGYVIIKK 517
Query: 342 PLDYETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSF 401
PLD+ET +++ EN E LVF + A++ A ++ VTD N+ P F F
Sbjct: 518 PLDFETAAVSNIVFKAENPEPLVFGVK------YNASSFAKFTLIVTDVNEAPQFSQHVF 571
Query: 402 IVNKEEGARPGTLLGTFNAMDPDS-QIRYELVHDPANWVSVDKNSGVVITVEPIDRESPH 460
E GT +G A DP+ I Y L D W+ +D +G + +V P+DRE+
Sbjct: 572 QAKVSEDVAIGTKVGNVTAKDPEGLDISYSLRGDTRGWLKIDHVTGEIFSVAPLDREA-- 629
Query: 461 VNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCES-AVHEPLH 519
S Y + + A + G ++ L L D+NDN P L + C + L
Sbjct: 630 --GSPYRVQVVATEVGGSSLSSVSEFHLILMDVNDNPPRLAKDYTGLFFCHPLSAPGSLI 687
Query: 520 IEAEDPDLEPFSDP-FTFELDNTWGNAEDTWKLGRNWGQSVELLTLRS-LPRGNYLVPLF 577
EA D D F P FTF L + G+ ++ W++ + G L T + Y+V +
Sbjct: 688 FEATDDDQHLFRGPHFTFSLGS--GSLQNDWEVSKINGTHARLSTRHTEFEEREYVVLIR 745
Query: 578 IGD--KQGLSQKQTVHVRICPCASGLTCVELADAE-----VGLHVGALFPVCAAFVALAV 630
I D + L ++ V C C G +C A + VG+ VG L + + +
Sbjct: 746 INDGGRPPLEGIVSLPVTFCSCVEG-SCFRPAGHQTGIPTVGMAVGILLTTLLV-IGIIL 803
Query: 631 ALLFL 635
A++F+
Sbjct: 804 AVVFI 808
Score = 96.3 bits (238), Expect = 1e-19
Identities = 83/322 (25%), Positives = 146/322 (45%), Gaps = 36/322 (11%)
Query: 114 GRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNIT 173
G +Y +R +DRE + + ++ + G IV+ + I++ D+ND+ P F + ++ +
Sbjct: 76 GLLYYNRALDRETRSTHNLQVAALD-ANGIIVEGPVPITIKVKDINDNRPTFLQSKYEGS 134
Query: 174 VQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKE-SGFRVDRLSGEIRLS-- 230
V++N G+P + A DLD+ TPN Q+ Y ++ Q P++ F+++ +G I L+
Sbjct: 135 VRQNSRPGKPFLYVNATDLDDPATPNGQLYYQIVIQLPMINNVMYFQINNKTGAISLTRE 194
Query: 231 GCLDYETA--PQFTLLIRARDCG---EPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIP 285
G + A P + L+I +D G E S S TT+V + V E P V++
Sbjct: 195 GSQELNPAKNPSYNLVISVKDMGGQSENSFSDTTSVDIIVTENIWKAPK------PVEMV 248
Query: 286 EGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDY 345
E +++ + P A+++++ + F S D EG + V +PLD
Sbjct: 249 ENSTDPHPIKITQVRWNDP-----GAQYSLVDKEKLPRFPFSID---QEGDIYVTQPLDR 300
Query: 346 ETRPAQSLIIVVENEERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIV-N 404
E + A V ++E + + + V+V D ND P P V
Sbjct: 301 EEKDAYVFYAVAKDEY------------GKPLSYPLEIHVKVKDINDNPPTCPSPVTVFE 348
Query: 405 KEEGARPGTLLGTFNAMDPDSQ 426
+E R G +GT A D D +
Sbjct: 349 VQENERLGNSIGTLTAHDRDEE 370
>gi|16306532 cadherin 11, type 2 preproprotein [Homo sapiens]
Length = 796
Score = 205 bits (522), Expect = 1e-52
Identities = 187/668 (27%), Positives = 308/668 (46%), Gaps = 79/668 (11%)
Query: 42 KEKIYQPLRRSKRRWVITTLELEEEDPGPFPKLIGELFNNM-SYNMSLMYLISGPGVDEY 100
K K Q L+RSKR WV + EE GP P L+G L +++ S + ++ Y++SG G
Sbjct: 41 KGKEGQVLQRSKRGWVWNQFFVIEEYTGPDPVLVGRLHSDIDSGDGNIKYILSGEGA--- 97
Query: 101 PEIGLFSLEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVND 160
G + D ++G I+ + +DRE +T+ V+R T + ++ F +++ D+ND
Sbjct: 98 ---GTIFVIDDKSGNIHATKTLDREERAQYTLMAQAVDRDTNRPLEPPSEFIVKVQDIND 154
Query: 161 HAPQFPEKEFNITVQENQSAGQPIFQMLAVDLDEENTPNSQVLYFLISQTPLLKESGFRV 220
+ P+F + ++ V E + G + Q+ A D D+ NS L + I L + F V
Sbjct: 155 NPPEFLHETYHANVPERSNVGTSVIQVTASDADDPTYGNSAKLVYSI----LEGQPYFSV 210
Query: 221 DRLSGEIRLS-GCLDYETAPQFTLLIRARDCG--EPSLSSTTTVHVDVQEGNNHRPAFTQ 277
+ +G IR + +D E ++ ++I+A+D G LS TT V + + + N++ P F Q
Sbjct: 211 EAQTGIIRTALPNMDREAKEEYHVVIQAKDMGGHMGGLSGTTKVTITLTDVNDNPPKFPQ 270
Query: 278 ENYKVQIPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGIL 337
Y++ + E A G V+ +D +NI+ G+ F+I+TD ET EG++
Sbjct: 271 SVYQMSVSEA-AVPGEEVGRVKAKDPDIGENGLVTYNIVDGDGMESFEITTDYETQEGVI 329
Query: 338 NVIKPLDYETRPAQSLIIVVENEE-RLVFCERGKLQPPRKAAASATVSVQVTDANDPPAF 396
+ KP+D+ET+ A SL + N F G + + TV + V DA++PP F
Sbjct: 330 KLKKPVDFETKRAYSLKVEAANVHIDPKFISNGPFKD------TVTVKISVEDADEPPMF 383
Query: 397 HPQSFIVNKEEGARPGTLLGTFNAMDPD---SQIRYELVH--DPANWVSVDKNSGVVITV 451
S+I +E A GT++G +A DPD S IRY + D + +++ G + T
Sbjct: 384 LAPSYIHEVQENAAAGTVVGRVHAKDPDAANSPIRYSIDRHTDLDRFFTINPEDGFIKTT 443
Query: 452 EPIDRESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTL-RPRSRYMEVC 510
+P+DRE ++ I + A + Q A + + + D+NDN P P + +C
Sbjct: 444 KPLDRE----ETAWLNITVFAAEIHNRHQEAKVPVAIRVLDVNDNAPKFAAPYEGF--IC 497
Query: 511 ESAVHEPLH------IEAEDPDLEPFSDPFTFEL----------------DNTWGNAEDT 548
ES +PL I A+D D F F L DNT G
Sbjct: 498 ESDQTKPLSNQPIVTISADDKDDTANGPRFIFSLPPEIIHNPNFTVRDNRDNTAG----- 552
Query: 549 WKLGRNWGQSVELLTLRSLPRGNYLVPLFIGDK--QGLSQKQTVHVRICPC---ASGLTC 603
R G S + L YL+P+ I D +S T+ +++C C + L+C
Sbjct: 553 -VYARRGGFSRQKQDL-------YLLPIVISDGGIPPMSSTNTLTIKVCGCDVNGALLSC 604
Query: 604 -VELADAEVGLHVGALFPVCAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEG-HQTLV 661
E GL GAL + A V L V ++ + + K+ V +E + ++
Sbjct: 605 NAEAYILNAGLSTGALIAILACIVILLVIVVLFVT---LRRQKKEPLIVFEEEDVRENII 661
Query: 662 MYNAESKG 669
Y+ E G
Sbjct: 662 TYDDEGGG 669
>gi|119703744 desmoglein 1 preproprotein [Homo sapiens]
Length = 1049
Score = 196 bits (499), Expect = 6e-50
Identities = 140/504 (27%), Positives = 248/504 (49%), Gaps = 23/504 (4%)
Query: 13 LLLVLLLWLLQVSIIDSVQQETDDLTKQTKEKIYQPLRRSKRRWVITTLELEEEDPGPFP 72
++ +L ++L+ V + + + D + + +RR KR W+ E +
Sbjct: 8 VVAMLFIFLVVVEVNSEFRIQVRDYNTKNGTIKWHSIRRQKREWIKFAAACREGEDNSKR 67
Query: 73 KLIGELFNNMSYNMSLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDREMTPSFTV 132
I ++ ++ + N + Y ISG G+D+ P G+F + + + G I + VDRE+TP F +
Sbjct: 68 NPIAKIHSDCAANQQVTYRISGVGIDQ-PPYGIFVI-NQKTGEINITSIVDREVTPFFII 125
Query: 133 YFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIFQMLAVDL 192
Y + S G+ ++ L +R+ D+ND+ P F F ++EN +A + + A D
Sbjct: 126 YCRALN-SMGQDLERPLELRVRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDA 184
Query: 193 DEENTPNSQVLYFLISQTPLLKESGFRVDRLSGEIR-LSGCLDYETAPQFTLLIRA--RD 249
DE N NS++ + +I Q P F ++R +GEIR ++ LD E Q+ L +R RD
Sbjct: 185 DEPNNLNSKIAFKIIRQEPS-DSPMFIINRNTGEIRTMNNFLDREQYGQYALAVRGSDRD 243
Query: 250 CGEPSLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGRASQGVLRLLVQDRDSPFTSAW 309
G +S+ ++ + + N++ P Q +Y ++I E + +L + V D D F++ W
Sbjct: 244 GGADGMSAECECNIKILDVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLDEEFSANW 303
Query: 310 RAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENEERLVFCERG 369
A + GNE F+I + TN GIL V+KPLDYE + L I V N+
Sbjct: 304 MAVIFFISGNEGNWFEIEMNERTNVGILKVVKPLDYEAMQSLQLSIGVRNKAEF----HH 359
Query: 370 KLQPPRKAAASATVSVQVTDANDPPAFHP--QSFIVNKEEGARPGTLLGTFNAMD----- 422
+ K ASA +SV V + + P F P ++++V G+ +G F A D
Sbjct: 360 SIMSQYKLKASA-ISVTVLNVIEGPVFRPGSKTYVVTGNMGS--NDKVGDFVATDLDTGR 416
Query: 423 PDSQIRYELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDDGFPPQTA 482
P + +RY + ++PA+ ++VD +G + + +E ++ Y I ++DD +T
Sbjct: 417 PSTTVRYVMGNNPADLLAVDSRTGKLTLKNKVTKEQYNMLGGKYQGTILSIDDNL-QRTC 475
Query: 483 TGTLMLFLSDI-NDNVPTLRPRSR 505
TGT+ + + ND+ P ++
Sbjct: 476 TGTININIQSFGNDDRTNTEPNTK 499
Score = 45.1 bits (105), Expect = 3e-04
Identities = 50/192 (26%), Positives = 90/192 (46%), Gaps = 19/192 (9%)
Query: 385 VQVTDAND-PPAFHPQSFIVNKEEGARPGTLLGTFNAMDPD------SQIRYELVH-DPA 436
V+V D ND PP F +F EE + TL+ NA D D S+I ++++ +P+
Sbjct: 145 VRVLDINDNPPVFSMATFAGQIEENSNANTLVMILNATDADEPNNLNSKIAFKIIRQEPS 204
Query: 437 N--WVSVDKNSGVVITVEP-IDRESPHVNNSFYVIIIHAVD--DGFPPQTATGTLMLFLS 491
+ +++N+G + T+ +DRE Y + + D G +A + +
Sbjct: 205 DSPMFIINRNTGEIRTMNNFLDREQ----YGQYALAVRGSDRDGGADGMSAECECNIKIL 260
Query: 492 DINDNVPTLRPRSRYMEVCESAVHEP-LHIEAEDPDLEPFSDPFTFELDNTWGNAEDTWK 550
D+NDN+P + S +E+ E+ ++ L I D D E FS + + GN + ++
Sbjct: 261 DVNDNIPYMEQSSYTIEIQENTLNSNLLEIRVIDLD-EEFSANWMAVIFFISGNEGNWFE 319
Query: 551 LGRNWGQSVELL 562
+ N +V +L
Sbjct: 320 IEMNERTNVGIL 331
>gi|4826673 cadherin 6, type 2 preproprotein [Homo sapiens]
Length = 790
Score = 196 bits (498), Expect = 7e-50
Identities = 183/651 (28%), Positives = 306/651 (47%), Gaps = 63/651 (9%)
Query: 49 LRRSKRRWVITTLELEEEDPGPFPKLIGELFNNMSY-NMSLMYLISGPGVDEYPEIGLFS 107
L RSKR W+ L EE G + +G+L ++ + SL Y++SG G + LF
Sbjct: 48 LNRSKRSWMWNQFFLLEEYTGSDYQYVGKLHSDQDRGDGSLKYILSGDGAGD-----LFI 102
Query: 108 LEDHENGRIYVHRPVDREMTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPE 167
+ ++ G I + +DRE P + + + R TG+ V+ F I+I D+ND+ P F +
Sbjct: 103 INEN-TGDIQATKRLDREEKPVYILRAQAINRRTGRPVEPESEFIIKIHDINDNEPIFTK 161
Query: 168 KEFNITVQENQSAGQPIFQMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGE 226
+ + TV E G + Q+ A D D+ NS +V+Y ++ P F V+ +G
Sbjct: 162 EVYTATVPEMSDVGTFVVQVTATDADDPTYGNSAKVVYSILQGQPY-----FSVESETGI 216
Query: 227 IRLSGC-LDYETAPQFTLLIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYKVQ 283
I+ + +D E Q+ ++I+A+D G LS TTTV++ + + N++ P F Q Y+ +
Sbjct: 217 IKTALLNMDRENREQYQVVIQAKDMGGQMGGLSGTTTVNITLTDVNDNPPRFPQSTYQFK 276
Query: 284 IPEGRASQGVLRLLVQDRDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPL 343
PE + G ++ D+ +++I G FD+ TD ET EGI+ V K L
Sbjct: 277 TPES-SPPGTPIGRIKASDADVGENAEIEYSITDGEGLDMFDVITDQETQEGIITVKKLL 335
Query: 344 DYETRPAQSLIIVVEN---EERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQS 400
D+E + +L + N E R ++ K SATV + V D ++PP F +
Sbjct: 336 DFEKKKVYTLKVEASNPYVEPRFLYLGPFK--------DSATVRIVVEDVDEPPVFSKLA 387
Query: 401 FIVNKEEGARPGTLLGTFNAMDPD---SQIRYELVH--DPANWVSVDKNSGVVITVEPID 455
+I+ E A+ T +G+ A DPD + ++Y + D ++D +G + T + +D
Sbjct: 388 YILQIREDAQINTTIGSVTAQDPDAARNPVKYSVDRHTDMDRIFNIDSGNGSIFTSKLLD 447
Query: 456 RESPHVNNSFYVIIIHAVDDGFPPQTATGTLMLFLSDINDNVPTLRPRSRYME--VCESA 513
RE+ +N I + A + P Q++ L + + D+NDN P + + E VCE A
Sbjct: 448 RETLLWHN----ITVIATEINNPKQSSRVPLYIKVLDVNDNAPEF---AEFYETFVCEKA 500
Query: 514 VHEPL--HIEAEDPDLEPFS-DPFTFELDNTWGNAEDTWKLGRNWGQSVELLTLRS---- 566
+ L + A D D +P+S F+F L + + + + N + +LT ++
Sbjct: 501 KADQLIQTLHAVDKD-DPYSGHQFSFSLAPEAASGSN-FTIQDNKDNTAGILTRKNGYNR 558
Query: 567 LPRGNYLVPLFIGDKQGLSQKQ--TVHVRICPC---ASGLTC-VELADAEVGLHVGALFP 620
YL+P+ I D Q TV VR+C C + +C E GL GAL
Sbjct: 559 HEMSTYLLPVVISDNDYPVQSSTGTVTVRVCACDHHGNMQSCHAEALIHPTGLSTGALVA 618
Query: 621 V--CAAFVALAVALLFLLRCYFVLEPKRHGCSVSNDEGHQTLVMYNAESKG 669
+ C + + V L LR + K+ +S ++ +V YN E G
Sbjct: 619 ILLCIVILLVTVVLFAALR----RQRKKEPLIISKEDIRDNIVSYNDEGGG 665
>gi|16445393 cadherin 12, type 2 preproprotein [Homo sapiens]
Length = 794
Score = 195 bits (495), Expect = 2e-49
Identities = 192/687 (27%), Positives = 313/687 (45%), Gaps = 59/687 (8%)
Query: 15 LVLLLWLL-QVSIIDSVQQETDDL--TKQTKEKIYQPLRRS-----KRRWVITTLELEEE 66
L LLLW+L ++ +Q + T+ + I+ P +RS KR WV + EE
Sbjct: 7 LSLLLWVLFDGGLLTPLQPQPQQTLATEPRENVIHLPGQRSHFQRVKRGWVWNQFFVLEE 66
Query: 67 DPGPFPKLIGELFNNMSYNM-SLMYLISGPGVDEYPEIGLFSLEDHENGRIYVHRPVDRE 125
G P+ +G+L +++ ++ Y +SG G G D G I+ R +DRE
Sbjct: 67 YVGSEPQYVGKLHSDLDKGEGTVKYTLSGDGA------GTVFTIDETTGDIHAIRSLDRE 120
Query: 126 MTPSFTVYFDVVERSTGKIVDTSLIFNIRISDVNDHAPQFPEKEFNITVQENQSAGQPIF 185
P +T+ V+ T K ++ F I++ D+ND+ P+F + + TV E G +
Sbjct: 121 EKPFYTLRAQAVDIETRKPLEPESEFIIKVQDINDNEPKFLDGPYVATVPEMSPVGAYVL 180
Query: 186 QMLAVDLDEENTPNS-QVLYFLISQTPLLKESGFRVDRLSGEIRLS-GCLDYETAPQFTL 243
Q+ A D D+ NS +V+Y ++ P F +D +G IR + +D E Q+ +
Sbjct: 181 QVKATDADDPTYGNSARVVYSILQGQPY-----FSIDPKTGVIRTALPNMDREVKEQYQV 235
Query: 244 LIRARDCGEP--SLSSTTTVHVDVQEGNNHRPAFTQENYKVQIPEGR-ASQGVLRLLVQD 300
LI+A+D G L+ TT V++ + + N++ P F + + +++PE + R+ D
Sbjct: 236 LIQAKDMGGQLGGLAGTTIVNITLTDVNDNPPRFPKSIFHLKVPESSPIGSAIGRIRAVD 295
Query: 301 RDSPFTSAWRAKFNILHGNEEGHFDISTDPETNEGILNVIKPLDYETRPAQSLIIVVENE 360
D F ++NI+ G+ FDI TD +T EG++ + KPLD+ET+ A + + N
Sbjct: 296 PD--FGQNAEIEYNIVPGDGGNLFDIVTDEDTQEGVIKLKKPLDFETKKAYTFKVEASN- 352
Query: 361 ERLVFCERGKLQPPRKAAASATVSVQVTDANDPPAFHPQSFIVNKEEGARPGTLLGTFNA 420
L R P K +ATV + V D ++PP F + + E GT++G A
Sbjct: 353 --LHLDHRFHSAGPFK--DTATVKISVLDVDEPPVFSKPLYTMEVYEDTPVGTIIGAVTA 408
Query: 421 MDPD---SQIRY--ELVHDPANWVSVDKNSGVVITVEPIDRESPHVNNSFYVIIIHAVDD 475
D D S +RY + D ++ ++D N G + T E +DRES N + II V +
Sbjct: 409 QDLDVGSSAVRYFIDWKSDGDSYFTIDGNEGTIATNELLDRESTAQYN--FSIIASKVSN 466
Query: 476 GFPPQTATGTLMLFLSDINDNVPTLRPRSRYMEVCESAVHEPL--HIEAEDPDLEPFSDP 533
P T+ +++ + D+N+ P + VCE+A + + A D DL P
Sbjct: 467 --PLLTSKVNILINVLDVNEFPPEISVPYE-TAVCENAKPGQIIQIVSAADRDLSPAGQQ 523
Query: 534 FTFELDNTWG-NAEDTWKLGRNWGQSVELLTLRSLPRGN--YLVPLFIGDKQ--GLSQKQ 588
F+F L T + RN +E R Y +P+ I D S
Sbjct: 524 FSFRLSPEAAIKPNFTVRDFRNNTAGIETRRNGYSRRQQELYFLPVVIEDSSYPVQSSTN 583
Query: 589 TVHVRICPCASG---LTC-VELADAEVGLHVGALFPV--CAAFVALAVALLFLLRCYFVL 642
T+ +R+C C S L+C VE VGL GAL + C + V L LR
Sbjct: 584 TMTIRVCRCDSDGTILSCNVEAIFLPVGLSTGALIAILLCIVILLAIVVLYVALR----R 639
Query: 643 EPKRHGCSVSNDEGHQTLVMYNAESKG 669
+ K+ S ++ ++ Y+ E G
Sbjct: 640 QKKKDTLMTSKEDIRDNVIHYDDEGGG 666
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,683,459
Number of Sequences: 37866
Number of extensions: 1664866
Number of successful extensions: 7588
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 19
Number of HSP's that attempted gapping in prelim test: 3824
Number of HSP's gapped (non-prelim): 926
length of query: 832
length of database: 18,247,518
effective HSP length: 111
effective length of query: 721
effective length of database: 14,044,392
effective search space: 10126006632
effective search space used: 10126006632
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.