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Search of human proteins with 122937255
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122937255 NEZHA isoform 1 [Homo sapiens]
(1276 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122937255 NEZHA isoform 1 [Homo sapiens] 2561 0.0
gi|130502140 NEZHA isoform 2 [Homo sapiens] 2484 0.0
gi|44955929 calmodulin regulated spectrin-associated protein 1-l... 658 0.0
gi|186659512 calmodulin regulated spectrin-associated protein 1 ... 367 e-101
gi|163965366 nascent polypeptide-associated complex alpha subuni... 72 3e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 72 4e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 69 3e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 67 1e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 67 1e-10
gi|150378539 piccolo isoform 1 [Homo sapiens] 67 1e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 65 3e-10
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 63 2e-09
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 62 3e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 4e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 4e-09
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 61 8e-09
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 60 1e-08
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 60 1e-08
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 60 1e-08
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 60 1e-08
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 60 1e-08
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 60 1e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 60 1e-08
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 60 1e-08
gi|157785645 SPEG complex locus [Homo sapiens] 60 2e-08
gi|39930375 enabled homolog isoform b [Homo sapiens] 59 2e-08
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 59 2e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 59 4e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 59 4e-08
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 59 4e-08
>gi|122937255 NEZHA isoform 1 [Homo sapiens]
Length = 1276
Score = 2561 bits (6637), Expect = 0.0
Identities = 1276/1276 (100%), Positives = 1276/1276 (100%)
Query: 1 MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF 60
MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF
Sbjct: 1 MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF 60
Query: 61 YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER 120
YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER
Sbjct: 61 YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER 120
Query: 121 PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL 180
PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL
Sbjct: 121 PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL 180
Query: 181 QEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHAIAFCLKESGSKPPMIRYRKD 240
QEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHAIAFCLKESGSKPPMIRYRKD
Sbjct: 181 QEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHAIAFCLKESGSKPPMIRYRKD 240
Query: 241 RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV 300
RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV
Sbjct: 241 RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV 300
Query: 301 QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA 360
QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA
Sbjct: 301 QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA 360
Query: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW 420
SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW
Sbjct: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW 420
Query: 421 NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP 480
NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP
Sbjct: 421 NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP 480
Query: 481 GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP 540
GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP
Sbjct: 481 GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP 540
Query: 541 TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ 600
TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ
Sbjct: 541 TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ 600
Query: 601 LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG 660
LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG
Sbjct: 601 LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG 660
Query: 661 KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH 720
KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH
Sbjct: 661 KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH 720
Query: 721 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK 780
EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK
Sbjct: 721 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK 780
Query: 781 AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF 840
AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF
Sbjct: 781 AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF 840
Query: 841 SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE 900
SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE
Sbjct: 841 SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE 900
Query: 901 EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE 960
EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE
Sbjct: 901 EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE 960
Query: 961 EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD 1020
EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD
Sbjct: 961 EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD 1020
Query: 1021 LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS 1080
LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS
Sbjct: 1021 LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS 1080
Query: 1081 TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY 1140
TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY
Sbjct: 1081 TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY 1140
Query: 1141 KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY 1200
KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY
Sbjct: 1141 KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY 1200
Query: 1201 TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW 1260
TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW
Sbjct: 1201 TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW 1260
Query: 1261 QGKKPTTPKKGGGTPK 1276
QGKKPTTPKKGGGTPK
Sbjct: 1261 QGKKPTTPKKGGGTPK 1276
>gi|130502140 NEZHA isoform 2 [Homo sapiens]
Length = 1249
Score = 2484 bits (6437), Expect = 0.0
Identities = 1249/1276 (97%), Positives = 1249/1276 (97%), Gaps = 27/1276 (2%)
Query: 1 MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF 60
MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF
Sbjct: 1 MVEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPF 60
Query: 61 YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER 120
YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER
Sbjct: 61 YTDQYAQEHVKPPVTRLLLSAELYCRAWRQALPQLETPPNPSALLALLARRGTVPALPER 120
Query: 121 PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL 180
PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL
Sbjct: 121 PVREADLRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTSLEHKLLFWVDTTVRRL 180
Query: 181 QEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHAIAFCLKESGSKPPMIRYRKD 240
QEKTEQEAAQRASPAAPADGAAPAQPS IRYRKD
Sbjct: 181 QEKTEQEAAQRASPAAPADGAAPAQPS---------------------------IRYRKD 213
Query: 241 RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV 300
RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV
Sbjct: 214 RVVARRAPCFPTVTSLQDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVADSLYNLQLV 273
Query: 301 QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA 360
QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA
Sbjct: 274 QDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAA 333
Query: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW 420
SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW
Sbjct: 334 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW 393
Query: 421 NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP 480
NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP
Sbjct: 394 NRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEP 453
Query: 481 GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP 540
GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP
Sbjct: 454 GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRP 513
Query: 541 TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ 600
TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ
Sbjct: 514 TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQ 573
Query: 601 LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG 660
LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG
Sbjct: 574 LVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG 633
Query: 661 KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH 720
KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH
Sbjct: 634 KSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPH 693
Query: 721 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK 780
EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK
Sbjct: 694 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK 753
Query: 781 AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF 840
AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF
Sbjct: 754 AASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF 813
Query: 841 SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE 900
SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE
Sbjct: 814 SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEE 873
Query: 901 EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE 960
EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE
Sbjct: 874 EASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE 933
Query: 961 EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD 1020
EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD
Sbjct: 934 EAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDD 993
Query: 1021 LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS 1080
LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS
Sbjct: 994 LDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLS 1053
Query: 1081 TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY 1140
TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY
Sbjct: 1054 TVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLY 1113
Query: 1141 KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY 1200
KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY
Sbjct: 1114 KEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALY 1173
Query: 1201 TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW 1260
TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW
Sbjct: 1174 TLSGETEELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLW 1233
Query: 1261 QGKKPTTPKKGGGTPK 1276
QGKKPTTPKKGGGTPK
Sbjct: 1234 QGKKPTTPKKGGGTPK 1249
>gi|44955929 calmodulin regulated spectrin-associated protein 1-like 1
[Homo sapiens]
Length = 1478
Score = 658 bits (1698), Expect = 0.0
Identities = 519/1544 (33%), Positives = 730/1544 (47%), Gaps = 360/1544 (23%)
Query: 9 PGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPFYTDQYAQE 68
P +R+TF+VP IK D YDFSRAK A +LAW++ AFG E+VP EL EPFYTDQY QE
Sbjct: 7 PREMRKTFIVPAIKPFDHYDFSRAKIACNLAWLVAKAFG-TENVPEELQEPFYTDQYDQE 65
Query: 69 HVKPPVTRLLLSAELYCRAWRQALPQLETPP--NPSALLALLARRGTVPALPERPVREAD 126
H+KPPV LLLSAELYCRA L P A++ LA++G E+ V E D
Sbjct: 66 HIKPPVVNLLLSAELYCRAGSLILKSDAAKPLLGHDAVIQALAQKGLYVTDQEKLVTERD 125
Query: 127 LRHQPILMGAHLAVIDALMAAFAFEWTKTLPGPLALTS--------------LEHKLLFW 172
L +PI M AHLA+ID LM A+ E ++ +A +E +++W
Sbjct: 126 LHKKPIQMSAHLAMIDTLMMAYTVEMV-SIEKVIACAQQYSAFFQATDLPYDIEDAVMYW 184
Query: 173 VDTTVRRLQEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHAIAFCLKESGSKP 232
++ L++ EQE + A G A
Sbjct: 185 INKVNEHLKDIMEQEQKLKEHHTVEAPGGQKA---------------------------- 216
Query: 233 PMIRYRKDRVVARRAPCFPTVTSL-QDLASGAALAATIHCYCPQLLRLEEVCLKDPMSVA 291
RYRK++ + ++ PC P V +L +D G ALAA IH YCP ++RLE++CLK+ MS+A
Sbjct: 217 ---RYRKEQTLLKQLPCIPLVENLLKDGTDGCALAALIHFYCPDVVRLEDICLKETMSLA 273
Query: 292 DSLYNLQLVQDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQ- 350
DSLYNLQL+Q+FC L + C +LED+LY +K N +V +AELF FEV+KP FVQ
Sbjct: 274 DSLYNLQLIQEFCQEYLNQCCHFTLEDMLYAASSIKSNYLVFMAELFWWFEVVKPSFVQP 333
Query: 351 ----------VKDLPDG---HAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPL 397
VKD+P +AA ++S +SG + H L S
Sbjct: 334 RVVRPQGAEPVKDMPSIPVLNAAKRNVLDSSSDFPSSGEGATFTQSHHHLPSRYSRPQAH 393
Query: 398 RGSTGSLKSSPSMSHMEALGKAW----------------------------NRQLSRPLS 429
++G ++ S SMS+++ W NR ++R +S
Sbjct: 394 SSASGGIRRSSSMSYVDGFIGTWPKEKRSSVHGVSFDISFDKEDSVQRSTPNRGITRSIS 453
Query: 430 ----------------------------QAVSFSTPFGLDSDVDVVMGDPVLLRSVSS-D 460
+A S +DS D+ P+ ++S +
Sbjct: 454 NEGLTLNNSHVSKHIRKNLSFKPINGEEEAESIEEELNIDSHSDLKSCVPLNTNELNSNE 513
Query: 461 SLGPPRPAPARTPTQPPPEPG---DLPTIEEALQIIHSAEPRL---LPDGAADGSFYLHS 514
++ P A E G + P+IEEALQIIH E PD A+G F+LHS
Sbjct: 514 NIHYKLPNGALQNRILLDEFGNQIETPSIEEALQIIHDTEKSPHTPQPDQIANG-FFLHS 572
Query: 515 PE----------GPSKPSLASPYLPEGTSKPLSDRP-TKAPVYMPH---PETPSKPSPCL 560
E S P + +G P++D +++P PET + S
Sbjct: 573 QEMSILNSNIKLNQSSPDNVTD--TKGALSPITDNTEVDTGIHVPSEDIPETMDEDSSLR 630
Query: 561 ---------VGEASK----------------PPAPSEGSPKAVASSPAATNSEVKMTSFA 595
+ +ASK P PS S K+ S A+++S VKMTSFA
Sbjct: 631 DYTVSLDSDMDDASKFLQDYDIRTGNTREALSPCPSTVSTKSQPGSSASSSSGVKMTSFA 690
Query: 596 ERK-KQLVKAEAEA-GAGSPTSTPAPPEA--------------------------LSSEM 627
E+K ++L + ++ G+ S +TP E L+SEM
Sbjct: 691 EQKFRKLNHTDGKSSGSSSQKTTPEGSELNIPHVVAWAQIPEETGLPQGRDTTQLLASEM 750
Query: 628 SELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASG-------EAEAEA 680
L +LEEKRRAIEAQK+++EA F K RQ++G++AFL V ++ G A AE
Sbjct: 751 VHLRMKLEEKRRAIEAQKKKMEAAFTKQRQKMGRTAFLTVVKKKGDGISPLREEAAGAED 810
Query: 681 EEADSGPVPGGERPAGEGQG--------EPTSRPKAVTFSPDLGPVPHEG---------- 722
E+ + E +GQ E P+A P+ E
Sbjct: 811 EKVYTDRAKEKESQKTDGQRSKSLADIKESMENPQAKWLKSPTTPIDPEKQWNLASPSEE 870
Query: 723 ------LGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLL----------APPEA------ 760
+ EY +++ KL+++L LQ++MQRL+ QQ+ L+ +PP+
Sbjct: 871 TLNEGEILEYTKSIEKLNSSLHFLQQEMQRLSLQQEMLMQMREQQSWVISPPQPSPQKQI 930
Query: 761 ----PGSAPPPAAWVIPGPTTGPKAASPSP--ARRVPAT-----RRSPGPGPSQ-SPRSP 808
P ++ + P + P+ PSP + R A+ +R+P P + +P +
Sbjct: 931 RDFKPSKQAGLSSAIAPFSSDSPRPTHPSPQSSNRKSASFSVKSQRTPRPNELKITPLNR 990
Query: 809 KHTRPAELRLAPLTRVLTPPH-----------DVDSLPHLRKFSPSQV------------ 845
T P + P R +P D P L++ P +
Sbjct: 991 TLTPPRSVDSLPRLRRFSPSQVPIQTRSFVCFGDDGEPQLKESKPKEEVKKEELESKGTL 1050
Query: 846 -------------PVQTRSSILLA--------------EETPPEEPAARP---------- 868
P ++ S +L+ + P EP +P
Sbjct: 1051 EQRGHNPEEKEIKPFESTVSEVLSLPVTETVCLTPNEDQLNQPTEPPPKPVFPPTAPKNV 1110
Query: 869 GLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQ 928
LIE+ L L P D P D ++ + + +V GFF+KD+ K E++MA
Sbjct: 1111 NLIEVSLSDLKPPEKADV----PVEKYDGESDKEQFDDDQKVCCGFFFKDDQKAENDMAM 1166
Query: 929 KRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPA 988
KRA+LLE++ RR +E + RKQ E E E ++EE R +EE
Sbjct: 1167 KRAALLEKRLRREKETQLRKQQLEAEMEHKKEETRRKTEEE------------------- 1207
Query: 989 ARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRAAGSGGPGRGGRRATRPRSG 1048
R E+E R +F RQEY RR QLKLM+D+D V++PR P ++ RP+S
Sbjct: 1208 -RQKKEDERARR--EFIRQEYMRRKQLKLMEDMDTVIKPR------PQVVKQKKQRPKSI 1258
Query: 1049 CCDDSALARSPARGLLGSRLSKIYSQSTLSLSTVANEAHNNLGVKRPTSRAPSPSGLMSP 1108
D ++P +G + S S SL+T NE+ ++ + T R+ S G +SP
Sbjct: 1259 HRDHIESPKTPIKG------PPVSSLSLASLNTGDNESVHS---GKRTPRSESVEGFLSP 1309
Query: 1109 SRLPGSR--ERDWENGSNASSPASVPEYTGPRLYKEPSAKSNKFIIHNALSHCCLAGKVN 1166
SR GSR E+DWEN S SS AS EYTGP+LYKEPSAKSNK II NAL+HCCLAGKVN
Sbjct: 1310 SRC-GSRNGEKDWENASTTSSVASGTEYTGPKLYKEPSAKSNKHIIQNALAHCCLAGKVN 1368
Query: 1167 EPQKNRILEEIEKSKANHFLILFRDSSCQFRALYTLSGETEELSRLAGYGPRTVTPAMVE 1226
E QK +ILEE+EKS AN+FLILFRDS CQFR+LYT ETEE+++L G GP+++T M+E
Sbjct: 1369 EGQKKKILEEMEKSDANNFLILFRDSGCQFRSLYTYCPETEEINKLTGIGPKSITKKMIE 1428
Query: 1227 GIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLWQGKKPTTPKK 1270
G+YKYNSDRK+F+ IPAKT+S SVDA TI HLWQ K+P TPKK
Sbjct: 1429 GLYKYNSDRKQFSHIPAKTLSASVDAITIHSHLWQTKRPVTPKK 1472
>gi|186659512 calmodulin regulated spectrin-associated protein 1 [Homo
sapiens]
Length = 1602
Score = 367 bits (941), Expect = e-101
Identities = 305/903 (33%), Positives = 413/903 (45%), Gaps = 200/903 (22%)
Query: 513 HSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSE 572
H G + P + S Y+ E S L + K + + + SPCL
Sbjct: 750 HDFMGEAHPVVFSRYIGEEESAKLQE-DMKVKEHEDKDDASGRSSPCL------------ 796
Query: 573 GSPKAVASSPAATNSEVKMTSFAERKKQ-LVKAEAEAGAGSPTST--------PAP---- 619
S + SS + + VKMTSFAERK Q L E ++ S T PAP
Sbjct: 797 -STASQMSSVSMASGSVKMTSFAERKLQRLNSCETKSSTSSSQKTTPDASESCPAPLTTW 855
Query: 620 ---------------PEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAF 664
L+SE+ +L +LEEKRRAIEAQK+++EA+ A+ R +LGK+AF
Sbjct: 856 RQKREQSPSQHGKDPASLLASELVQLHMQLEEKRRAIEAQKKKMEALSARQRLKLGKAAF 915
Query: 665 LQVQPR-----------------------EASGEA----------EAEAEEADSGPVPGG 691
L V + E G+A E + EE P
Sbjct: 916 LHVVKKGKAEAAPPLRPEHFAKEYSQHNGEDCGDAVSKTEDFLVKEEQREELLHEPQDVD 975
Query: 692 ERPAGEGQGEPTSRP------------KAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSS 739
+ Q P A +G V + E + ++ KL+ +S+
Sbjct: 976 KESLAFAQQHKAKDPVALHELERNKVISAALLEDTVGEVVD--VNECDLSIEKLNETIST 1033
Query: 740 LQRDMQRLTDQQQRLLAPPEA---PGS--------APPPAAWVIPGPTTG---------- 778
LQ+ + +++ QQ++LL PGS P +V P TG
Sbjct: 1034 LQQAILKISQQQEQLLMKSPTVPVPGSKNNSQDHKVKAPVHFVEPLSPTGVAGHRKAPRL 1093
Query: 779 --------------------PKAAS----------------PSPARRVPATRRSPGPGPS 802
P+ +S P PA P T PG +
Sbjct: 1094 GQGRNSRSGRPAELKVPKDRPQGSSRSKTPTPSVETLPHLRPFPASSHPRTPTDPGLDSA 1153
Query: 803 QSPRSPKHTR----PAELRLAPLTRVLTPPHDVD--------SLPHLRKFSPSQVPVQTR 850
P H + L R LT D SL + S +V +
Sbjct: 1154 LEPSGDPHGKCLFDSYRLHDESNQRTLTLSSSKDANILSEQMSLKEVLDASVKEVG-SSS 1212
Query: 851 SSILLAEETPPEEPA-ARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPR 909
S + E P EEP +R LIE+ L L P + DG + S + SEG+ +
Sbjct: 1213 SDVSGKESVPVEEPLRSRASLIEVDLSDLKAP----DEDGELVSLDGSAD--LVSEGDQK 1266
Query: 910 VGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEE 969
G+GFF+KDE K EDE+A+KRA+ L +QQR+AEEAR RKQ E E E +R+EA R A+E+
Sbjct: 1267 PGVGFFFKDEQKAEDELAKKRAAFLLKQQRKAEEARVRKQQLEAEVELKRDEARRKAEED 1326
Query: 970 APGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRA 1029
R EEE R + +QEY RR Q +++++
Sbjct: 1327 --------------------RVRKEEEKARR--ELIKQEYLRRKQQQILEE--------- 1355
Query: 1030 AGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLSTVAN-EAHN 1088
G G P + + RP+S ++S LS+ S S+LSL++ A E +
Sbjct: 1356 QGLGKP-KSKPKKPRPKSVHREESCSDSGTKCSSTPDNLSRTQSGSSLSLASAATTEPES 1414
Query: 1089 NLGVKRPTSRAPSPSGLMSPSRLPG-SRERDWENGSNASSPASVPEYTGPRLYKEPSAKS 1147
P+ R S L SR P S +RDWE S ASS ASV EYTGP+L+KEPS+KS
Sbjct: 1415 VHSGGTPSQRVESMEALPILSRNPSRSTDRDWETASAASSLASVAEYTGPKLFKEPSSKS 1474
Query: 1148 NKFIIHNALSHCCLAGKVNEPQKNRILEEIEKSKANHFLILFRDSSCQFRALYTLSGETE 1207
NK IIHNA+SHCCLAGKVNEP KN ILEE+EK ANH++ILFRD+ CQFRALY +TE
Sbjct: 1475 NKPIIHNAISHCCLAGKVNEPHKNSILEELEKCDANHYIILFRDAGCQFRALYCYYPDTE 1534
Query: 1208 ELSRLAGYGPRTVTPAMVEGIYKYNSDRKRFTQIPAKTMSMSVDAFTIQGHLWQGKKPTT 1267
E+ +L G GP+ +T M++ +YKY+SDRK+F IPAKTMS+SVDA TI HLWQ K+P
Sbjct: 1535 EIYKLTGTGPKNITKKMIDKLYKYSSDRKQFNLIPAKTMSVSVDALTIHNHLWQPKRPAV 1594
Query: 1268 PKK 1270
PKK
Sbjct: 1595 PKK 1597
Score = 231 bits (589), Expect = 3e-60
Identities = 201/665 (30%), Positives = 300/665 (45%), Gaps = 141/665 (21%)
Query: 2 VEAAPPGPGPLRRTFLVPEIKSLDQYDFSRAKAAASLAWVLRAAFGGAEHVPPELWEPFY 61
+EA P G L VP LD+YD +RAK AA+L W+ A+G +++P +L +PFY
Sbjct: 16 MEAPPDGAADL-----VP----LDRYDAARAKIAANLQWICAKAYG-RDNIPEDLRDPFY 65
Query: 62 TDQYAQEHVKPPVTRLLLSAELYCRAWRQAL--PQLETPPNPSALLALLARRGT-VPALP 118
DQY QEH+KPPV +LLLS+ELYCR L Q+ +++ L+R+G V
Sbjct: 66 VDQYEQEHIKPPVIKLLLSSELYCRVCSLILKGDQVAALQGHQSVIQALSRKGIYVMESD 125
Query: 119 ERPVREADLRHQPILMGAHLAVIDALMAAF------------------AFEWTKTLPGPL 160
+ PV E+DL PI M AH+A++DALM A+ F +K LP
Sbjct: 126 DTPVTESDLSRAPIKMSAHMAMVDALMMAYTVEMISIEKVVASVKRFSTFSASKELP--- 182
Query: 161 ALTSLEHKLLFWVDTTVRRLQEKTEQEAAQRASPAAPADGAAPAQPSCPTRWYWKLVPHA 220
LE ++FW++ +++E TE+E +
Sbjct: 183 --YDLEDAMVFWINKVNLKMREITEKEVKLKQQ--------------------------- 213
Query: 221 IAFCLKESGSKPPMIRYRKDRVVARRAPCFPTVTSL-QDLASGAALAATIHCYCPQLLRL 279
L ES + +RYR++ + AR++P FP + L +D + GAAL A IH YCP+ ++L
Sbjct: 214 ----LLESPAH-QKVRYRREHLSARQSPYFPLLEDLMRDGSDGAALLAVIHYYCPEQMKL 268
Query: 280 EEVCLKDPMSVADSLYNLQLVQDFCASRLPRGCPLSLEDLLYVPPPLKVNLVVMLAELFM 339
+++CLK+ S+ADSLYN++L+++F L + L+LED+LY P LK N++V +AELF
Sbjct: 269 DDICLKEVTSMADSLYNIRLLREFSNEYLNKCFYLTLEDMLYAPLVLKPNVMVFIAELFW 328
Query: 340 CFEVLKPDFVQVKDLPD----------------------------GHAASPRGTEASPP- 370
FE +KPDFVQ +D+ + G A+ E PP
Sbjct: 329 WFENVKPDFVQPRDVQELKDAKTVLHQKSSRPPVPISNATKRSFLGSPAAGTLAELQPPV 388
Query: 371 ----------------QNNSGSSSPVFTFRHPLL--------SSGGPQSP-LRGSTGSLK 405
G + F+ HPLL S G P R + SL
Sbjct: 389 QLPAEGCHRHYLHPEEPEYLGKGTAAFSPSHPLLPLRQKQQKSIQGEDIPDQRHRSNSLT 448
Query: 406 SSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPV-LLRSVSSDSLG- 463
A+ AW + +RP SQ F+ +VD GD + L RS+S DSL
Sbjct: 449 RVDGQPRGAAI--AWPEKKTRPASQPTPFALHHAASCEVDPSSGDSISLARSISKDSLAS 506
Query: 464 -------PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPE 516
+P P T + ++ +E +++ ++P AD F SP
Sbjct: 507 NIVNLTPQNQPHPTATKSHGKSLLSNVSIEDEEEELVAIVRADVVPQ-QADPEFPRASPR 565
Query: 517 GPSKPSLA-SPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSP 575
+ A SP TS+ D P+ MP P+K + E + EG P
Sbjct: 566 ALGLTANARSPQGQLDTSESKPDSFFLEPL-MPAVLKPAKEKQVITKEDER----GEGRP 620
Query: 576 KAVAS 580
+++ S
Sbjct: 621 RSIVS 625
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 72.4 bits (176), Expect = 3e-12
Identities = 147/607 (24%), Positives = 196/607 (32%), Gaps = 120/607 (19%)
Query: 354 LPDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHM 413
LP AS A PQN + + S P P G+ K +SH
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHT 757
Query: 414 EALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTP 473
AL + P + + +T + + L SVS + PP + P
Sbjct: 758 SALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGP 817
Query: 474 TQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSK-----PSLASPYL 528
P G+L + ++ E L G+ D HSP PS PS +P
Sbjct: 818 DTPI---GNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLS 874
Query: 529 PEGTSKPLSDRPTKAPVYMPHPE----TPS-KPSPCLVGEASKP------PAP----SEG 573
P+G + P + PT + V +P P+ TP+ K +P L +S P PAP +
Sbjct: 875 PKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASP 934
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSAR 633
SPK + PAAT K K A A SP PA P + +
Sbjct: 935 SPKGAPTPPAATPPSPKGGPATPSPKWAPTPPA-ATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 634 LEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGER 693
K + G V P G A + P
Sbjct: 994 PSPKGGPATPSPK-------------GAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 694 PAGEGQGEPTSRPKAVTFSPDLG-PVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQ 752
P+ +G T PK +P P P G
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPAATLPSPKGGP----------------------------- 1071
Query: 753 RLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPA-TRRSPGPG----------- 800
A P G+ PPAA P P GP SP A PA T SP G
Sbjct: 1072 ---ATPSLKGAPTPPAA-TPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 801 -PSQSPRSPKH-----------TRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQ 848
P+ +P SPK T PA +P + TPP P +P+ P
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP------PKGAPTTPAATPPS 1181
Query: 849 TRSSILLAEETP---PEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSE 905
+ LA +P P PAA P P G LA P SP GA + A++
Sbjct: 1182 PKGG--LATPSPKGAPTTPAATP---PSPKGGLATP--------SPKGAPTT---PAATP 1225
Query: 906 GEPRVGL 912
P+ GL
Sbjct: 1226 PSPKGGL 1232
Score = 65.1 bits (157), Expect = 4e-10
Identities = 127/569 (22%), Positives = 199/569 (34%), Gaps = 96/569 (16%)
Query: 355 PDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRG-STGSLKSSPSMSHM 413
P SP+G A+PP + P + P SP G +T S K +P+
Sbjct: 1152 PAATPPSPKGGLATPPPKGA-----------PTTPAATPPSPKGGLATPSPKGAPTTP-- 1198
Query: 414 EALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTP 473
A + L+ P + +TP + P + ++ + PP P P
Sbjct: 1199 AATPPSPKGGLATPSPKGAP-TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG--P 1255
Query: 474 TQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEG-- 531
PPP+ P +A P L G A +G P++ +P P+G
Sbjct: 1256 ATPPPKGAPTPP---------AATPPSLKGGLATPPH-----KGAPNPAVVTPPSPKGGP 1301
Query: 532 TSKPLSDRPTKAPVYMPHPE-TPSKPSPCLVGEASKPPAPSEGSPKAVASSPAAT-NSEV 589
+ P PT P P+ +P P P A PPA + SPK + PA T +S+
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPP---KGAPTPPAVTPPSPKGTPTLPATTPSSKG 1358
Query: 590 KMTSFAERKKQLVKAEAEAGAGSPTSTPAPPE---ALSSEMSELS--ARLEEKRRAIEAQ 644
T+ + ++ A + G P TP P+ A+ S + + A + + A
Sbjct: 1359 GPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT 1418
Query: 645 KRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEG------ 698
E + L A V ++A A S P G P+ +G
Sbjct: 1419 PVTREGAATPSKGDLTPPAVTPVSLKKA---------PATSAPKGGPATPSSKGDPTLPA 1469
Query: 699 ------QGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQ 752
+ P + A + SP P +G L A + S +++ ++
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMG-----APTLPAVIPSSPKEVPATPSSRR 1524
Query: 753 RLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPG-PGPSQSP------ 805
+AP S PA T PK A PA VP+ +++P P P ++P
Sbjct: 1525 DPIAPTATLLSKKTPA-------TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSK 1577
Query: 806 --RSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEE 863
SP P+ + AP + L P P + SP + P PE+
Sbjct: 1578 EASSPPAVTPSTYKGAPSPKELLIP------PAVTSPSPKEAPTPP-----AVTPPSPEK 1626
Query: 864 PAARPGLIEIPLGSLADPAAEDEGDGSPA 892
A P P P++ + SPA
Sbjct: 1627 GPATPAPKGTPTSPPVTPSSLKDSPTSPA 1655
Score = 63.9 bits (154), Expect = 9e-10
Identities = 154/645 (23%), Positives = 209/645 (32%), Gaps = 141/645 (21%)
Query: 313 PLSLEDLLYVPPPLKVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAASPRGTEASPPQN 372
P + E+ P P N LA L + E+ P V LP A +P GT+ +
Sbjct: 702 PTASENCPVAPSPQ--NTCAPLATLVLAPEI--PKSVPSPSLPP--AGTPPGTKKVDGIS 755
Query: 373 NSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLK---SSPSMSHMEALGKAWNRQLSRPLS 429
++ + +PV + + S S G+L SPS LG + + Q RP +
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS-----PLGVSVSPQTKRPPT 810
Query: 430 QAVSFS--TPFG-LDSDVDVVMGDPVLLRSVS----------SDSLGPPRPAPARTPTQ- 475
+ S TP G L S V V + S+S + S PP P A TP+
Sbjct: 811 KKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAV 870
Query: 476 ---------------PPPEPGDLPTIEE-----------ALQIIHSAEPRLLPDGAADGS 509
P P +LP +E AL + S+ + A G
Sbjct: 871 TPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGI 930
Query: 510 FYLHSPEGPSKPSLASPYLPEGTSKPLSDR--PTKAPVYMPHPET-PSKPSPCLVGEASK 566
SP+G P A+P P+G S + PT P P+ P+ PSP A
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSP---KGAPT 987
Query: 567 PPAPSEGSPKA-------------VASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSP 613
PPA + SPK A +P + T F + A + GSP
Sbjct: 988 PPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSP 1047
Query: 614 TSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREAS 673
+TP P A ++ + L P
Sbjct: 1048 AATPLPKGAPTTPAATL--------------------------------------PSPKG 1069
Query: 674 GEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSP-DLGPVPHEGLGEYNRAVSK 732
G A + A P P P G T PK P P P GL +
Sbjct: 1070 GPATPSLKGA---PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126
Query: 733 LSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTG-----PKAASPSPA 787
+ A + + L PP P AP A P P G PK A +PA
Sbjct: 1127 TTPAATP--------PSPKGGLATPP--PKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176
Query: 788 RRVPATRRS-PGPGPSQSPRSPKHTRPA--------ELRLAPLTRVLTPPHDVDSLPHLR 838
P+ + P P +P +P T P+ + AP T TPP L
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236
Query: 839 KFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIP--LGSLADP 881
P T S TPP + A P P G LA P
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281
Score = 61.6 bits (148), Expect = 5e-09
Identities = 139/567 (24%), Positives = 187/567 (32%), Gaps = 66/567 (11%)
Query: 357 GHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEAL 416
G SP T + P + G+ +P S+ P SP +G T K +P+ S +
Sbjct: 845 GSKDSPATTHSPTPPSPKGAPTP---------SAVTPLSP-KGVTLPPKETPTPSVVNLP 894
Query: 417 GKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQP 476
P QA + S + P R+ + P P+P PT P
Sbjct: 895 FPKEGPATPAP-KQAPALS----------MTSSSPKKARATPAPKGIPASPSPKGAPTPP 943
Query: 477 ---PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTS 533
PP P P + P + G SP+G P A+P P+G
Sbjct: 944 AATPPSPKGGPATPSPKW---APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGP 1000
Query: 534 KPLSDR--PTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKM 591
S + PT V P P+ +P G AS PPA + SPK SPAAT +
Sbjct: 1001 ATPSPKGAPTPPAVTPPSPKGSPAATPFPKG-ASTPPAATPPSPKG---SPAAT----PL 1052
Query: 592 TSFAERKKQLVKAEAEAGAGSPT--STPAPPEALSSEMSELSARLEEKRRAIE--AQKRR 647
A + G +P+ P PP A A K + A
Sbjct: 1053 PKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS 1112
Query: 648 IEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPK 707
+ A + + P G A + A + P P G G T PK
Sbjct: 1113 PKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG---GLATPPPK 1169
Query: 708 AVTFSPDLGPV-PHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPP 766
+P P P GL + + + A + + LA P G+
Sbjct: 1170 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATP---------PSPKGGLATPSPKGAPTT 1220
Query: 767 PAAWVIPGPTTGPKAASPSPARRVP-ATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVL 825
PAA P P G SP A P AT SP GP+ P T PA + +
Sbjct: 1221 PAA-TPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLA 1279
Query: 826 TPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP----PEEPAARPGLIEIPLGSLADP 881
TPPH P+ +P +S TP P P PG P G+ P
Sbjct: 1280 TPPH--KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPG-TPPPKGAPTPP 1336
Query: 882 AAEDEGDGSPAGAEDSLEEEASSEGEP 908
A SP G SS+G P
Sbjct: 1337 AVTPP---SPKGTPTLPATTPSSKGGP 1360
Score = 54.7 bits (130), Expect = 6e-07
Identities = 136/584 (23%), Positives = 193/584 (33%), Gaps = 144/584 (24%)
Query: 361 SPRGTEASP------------PQNNSGSSSPVFTFRHPLLSSGGPQSPLRG-STGSLKSS 407
SP+GT P P + G + P T H + P SP RG + S K
Sbjct: 1342 SPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGD 1401
Query: 408 PSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGD-------PVLLRSVSSD 460
P+ + PLS + +TP + GD PV L+ +
Sbjct: 1402 PTSPAVI------------PLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
Query: 461 SL---GPPRPAPARTPTQP---PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHS 514
S GP P+ PT P PP P + P + Q+ S+ P+ P A
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK---QVATSSSPKKAPATPA-------- 1498
Query: 515 PEG-PSKPSLASPYLPEGTSKPLSDRPTKAPVY-MPHPETPSKPSPCLVGEASKPPAPSE 572
P G P+ P++ E + P S R AP + +TP+ +P EA PPA +
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP---KEALIPPAMTV 1555
Query: 573 GSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSA 632
SPK + P + +S V GA SP PP S
Sbjct: 1556 PSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPS------ 1609
Query: 633 RLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGE 692
P+EA P P
Sbjct: 1610 ------------------------------------PKEA--------------PTPPAV 1619
Query: 693 RPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVS-KLSAALSSLQRDM---QRLT 748
P +G T PK SP + P + +V+ K+ A + + + + T
Sbjct: 1620 TPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPT 1679
Query: 749 DQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR-SPGPGPSQSPR- 806
++ L+AP AP S P A GP T +A+ P P+ + S GP + +P
Sbjct: 1680 ALKEVLVAP--APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP 1737
Query: 807 -------SPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEET 859
S K + + +P L PP S P +P +S+ A
Sbjct: 1738 LLPVQKDSSKTAKGKDASHSP-KGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSP 1796
Query: 860 PPEEPAA----------------RPGLI-EIPLGSLADPAAEDE 886
P P A PGL+ E P LA PA EDE
Sbjct: 1797 PVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA-PADEDE 1839
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 71.6 bits (174), Expect = 4e-12
Identities = 128/516 (24%), Positives = 178/516 (34%), Gaps = 111/516 (21%)
Query: 464 PPRPAPARTPTQPPPE-------PGDLPT--IEEALQIIHSAE----------------P 498
P P P +PT PPPE P +LP + EAL + E P
Sbjct: 448 PLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPP 507
Query: 499 RLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSP 558
P + S E P P+L +P P + PLS ++P+ P E P+ P P
Sbjct: 508 ESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPP 567
Query: 559 CLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTP- 617
EAS+ P E SP S P E M+ E + E + P +P
Sbjct: 568 ----EASRLSPPPEESP---MSPPP---EESPMSPPPEASRLFPPFEESPLSPPPEESPL 617
Query: 618 -APPEAL----SSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREA 672
PPEA E S +S EE + + R+ + R + P
Sbjct: 618 SPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSR----------LSPPPE 667
Query: 673 SGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSK 732
EE+ + P P R + + PTS P P P + L ++
Sbjct: 668 ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE---DSPASPPPEDSL----MSLPL 720
Query: 733 LSAALSSLQRDMQRLTDQQQRLLAP-PEAPGSAPPPAAWVIPGPTTGPKAASP--SPARR 789
+ L L + Q + L+P PE P +P P P P+A P SP
Sbjct: 721 EESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE-----PHLSPQAEEPHLSPQPE 775
Query: 790 VPATRRSP--------GPGPSQSPRSPKHTRPAELRLAPLTR-----------VLTP-PH 829
P P GP SP +P EL L+P T L+P P
Sbjct: 776 EPCLCAVPEEPHLSPQAEGPHLSP------QPEELHLSPQTEEPHLSPVPEEPCLSPQPE 829
Query: 830 DVDSLPHLRKFSPSQVPVQTRSSILLAE-------ETPPEEPAARPGLIEIPL------- 875
+ P + S P ++ S L + E PPEEP P E+PL
Sbjct: 830 ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEP 889
Query: 876 ---GSLADPAAEDEGDGSPAGAEDSLEEEASSEGEP 908
L +PA + G+ + + L S GEP
Sbjct: 890 SLSPLLGEPALSEPGEPPLSPLPEEL--PLSPSGEP 923
Score = 63.2 bits (152), Expect = 2e-09
Identities = 147/603 (24%), Positives = 205/603 (33%), Gaps = 99/603 (16%)
Query: 346 PDFVQVKDLPDGHAASPRGTEA--SPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGS 403
P+ + P+ SP E+ SPP S S P R L +SPL
Sbjct: 558 PEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR---LFPPFEESPLSPPPEE 614
Query: 404 LKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLG 463
SP + +S P ++ P +V + PV+ R
Sbjct: 615 SPLSPPPEASRLSPPPEDSPMSPPPEES-----PMSPPPEVSRLSPLPVVSRLSPPPEES 669
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P P P +PT PPPE L E E D L E P P
Sbjct: 670 PLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLP 729
Query: 524 ASPYL-PEGTSKPLSDRPTKAPVYMPHPE-------------TPSKPSPCLVGEASKPPA 569
P L P LS RP + P P PE +P PCL +P
Sbjct: 730 EEPQLCPRSEGPHLSPRPEE-PHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788
Query: 570 PSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSE 629
SP+A + E+ ++ E E P +P P E+ S SE
Sbjct: 789 ----SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPE------EPCLSPQPEESHLSPQSE 838
Query: 630 ---LSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAF-----LQVQPREAS-----GE- 675
LS R EE + E +K + K + G+ L P E S GE
Sbjct: 839 EPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEP 898
Query: 676 AEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSA 735
A +E E P+P E P GEP+ P+ + PD P P + A +
Sbjct: 899 ALSEPGEPPLSPLPE-ELPLSPS-GEPSLSPQLMP--PDPLPPPLSPI--ITAAAPPALS 952
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR 795
L L+ D PE+P +AP ++ P + P A+ + VP
Sbjct: 953 PLGELEYPFGAKGDSD------PESPLAAP-----ILETPISPPPEANCTDPEPVPPMIL 1001
Query: 796 SPGPGPSQSPRSPKHTRPAELRLAPLTR-VLTPPHDVDSLPHLRKFSPSQVPVQTRSSIL 854
P PG P SP P + +PL + L P + S + SP +P+ S +
Sbjct: 1002 PPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS-----QCSPPALPLSVPSPLS 1056
Query: 855 -------LAEE-----------TPPEEPAARPGL---IEIPLGSLADPAAEDEGDGSPAG 893
+++E + PE PA P + P+G L+ PA SPA
Sbjct: 1057 PIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDLSCPAP------SPAP 1110
Query: 894 AED 896
A D
Sbjct: 1111 ALD 1113
Score = 62.0 bits (149), Expect = 4e-09
Identities = 107/429 (24%), Positives = 145/429 (33%), Gaps = 103/429 (24%)
Query: 477 PPEPGDLPTIE-EALQIIHSAEPR------------------LLPDGAADGSF--YLHSP 515
PPEPGD PT E +AL + +P+ P G A L +P
Sbjct: 374 PPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 516 EGPSKPSL----ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPS 571
P L SP P P S P + + P E P+ P P EA P
Sbjct: 434 LNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLP----EALHLSRPL 489
Query: 572 EGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELS 631
E SP + + + + + F+ ++ + E+ TP P E S LS
Sbjct: 490 EESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP---PPEASPLS 546
Query: 632 ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGG 691
EE + ++ L P + EE+ P P
Sbjct: 547 PPFEESPLSPPPEE-------------------LPTSPPPEASRLSPPPEESPMSPPP-- 585
Query: 692 ERPAGEGQGEPTSRPKAVT--FSP----DLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQ 745
+ P S P + F P L P P E S LS
Sbjct: 586 -------EESPMSPPPEASRLFPPFEESPLSPPPEE---------SPLSP---------- 619
Query: 746 RLTDQQQRLLAPPE-APGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSP-GPGPSQ 803
+ RL PPE +P S PP + + P P + P +R P SP P P +
Sbjct: 620 --PPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEE 677
Query: 804 SPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP--- 860
SP SP P RL+P PP D + P + SP+ P + L EE+P
Sbjct: 678 SPTSPP---PEASRLSP------PPEDSPTSPP-PEDSPASPPPEDSLMSLPLEESPLLP 727
Query: 861 -PEEPAARP 868
PEEP P
Sbjct: 728 LPEEPQLCP 736
Score = 53.1 bits (126), Expect = 2e-06
Identities = 99/451 (21%), Positives = 158/451 (35%), Gaps = 111/451 (24%)
Query: 465 PRPAPARTPTQPPPE-PGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P+P P+ QPP PG ++ + ++H+A G + G G S +
Sbjct: 4082 PQPQPSSLQLQPPLRLPGQQ---QQQVSLLHTA------GGGSHGQL----GSGSSSEAS 4128
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPA 583
+ P+L S L D+P + P+ P P +PP P
Sbjct: 4129 SVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPG------------ 4176
Query: 584 ATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEA-LSSEMSELSARLEEKRRAIE 642
++G G P P L +++ + A+ + R
Sbjct: 4177 --------------------PVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSP 4216
Query: 643 AQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAE-----EADSGPVPG------- 690
Q+++++A+ + RQ A Q P + G + + + G PG
Sbjct: 4217 QQQQQLQALLMQ-RQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQ 4275
Query: 691 --GERPAGEGQGEPTSRPKAVTFSPDLGPV---PHEGLGEYNRAVSKLSAALSSLQRDMQ 745
G P +G + P A++ P LGPV P + + S+L + S L + Q
Sbjct: 4276 ELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Query: 746 RLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSP-ARRVPATRRSPGPGPSQS 804
PP PG+ P GPT P SP A ++ T S G GP
Sbjct: 4336 ----------LPPTHPGTPKP------QGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDP 4379
Query: 805 PRSPKHT-RPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEE 863
P + T +P + L P HL + + VP ++ SI ++ P EE
Sbjct: 4380 PDNLAETQKPEQSSLVP--------------GHLDQVNGQVVPEASQLSI---KQEPREE 4422
Query: 864 PAARPGLIEIPLGSLADPAAEDEGDGSPAGA 894
P A L + + E +G P GA
Sbjct: 4423 PCA-----------LGAQSVKREANGEPIGA 4442
Score = 41.6 bits (96), Expect = 0.005
Identities = 60/227 (26%), Positives = 80/227 (35%), Gaps = 45/227 (19%)
Query: 369 PPQNNSGSSSPVFTFRHPLLSSGG--PQSPLRGSTGSLKS--------SPSMSHM----- 413
P QNN+G P P+L SG P + + G L++ +P + H+
Sbjct: 4163 PMQNNTGPQPPK---PGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQ 4219
Query: 414 ---EALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPA 470
+AL Q S+ + Q + P S + ++G L GP + A
Sbjct: 4220 QQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGA 4279
Query: 471 RTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPE 530
Q PP LP AL S P L P +H PS P P P
Sbjct: 4280 GPRPQGPPR---LPAPPGAL----STGPVLGP---------VHPTPPPSSPQ--EPKRPS 4321
Query: 531 GTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKA 577
P S PT+A + HP TP P L P P SP A
Sbjct: 4322 QLPSPSSQLPTEAQLPPTHPGTPKPQGPTL------EPPPGRVSPAA 4362
Score = 40.0 bits (92), Expect = 0.014
Identities = 145/695 (20%), Positives = 232/695 (33%), Gaps = 109/695 (15%)
Query: 462 LGPPRPAPARTPTQPPPEPGDL----PTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEG 517
L P P PA+ PP D+ + Q + P+ P + P
Sbjct: 2347 LRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD 2406
Query: 518 PSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPA-PSEGSPK 576
P ASP + PL+ RP A + P P TP SP S+PP+ P P
Sbjct: 2407 PFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSP---DPYSRPPSRPQSRDPF 2463
Query: 577 AVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEE 636
A P + A + L AG G P + PA P EL A++
Sbjct: 2464 APLHKP----PRPQPPEVAFKAGSLAHTSLGAG-GFPAALPAGP------AGELHAKVPS 2512
Query: 637 KRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAG 696
+ + A +G + ++ +A GE + G P +
Sbjct: 2513 GQPPNFVRSPGTGAF-------VGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSH 2565
Query: 697 EGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLA 756
G G +P++ ++ G ++ + S L + S + +L
Sbjct: 2566 FGPGPTLGKPQSTNYT--------VATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP 2617
Query: 757 PPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAEL 816
PP GS P ++ G ++ SP + R PG G S + + +
Sbjct: 2618 PPAPDGSLP----YLSHG--ASQRSGITSPVEK----REDPGTGMGSSLATAELPGTQDP 2667
Query: 817 RLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLG 876
++ L++ +++ ++ + Q + + L E+ E AA G + P
Sbjct: 2668 GMSGLSQT-----ELEKQRQRQRLRELLIRQQIQRNTLRQEK---ETAAAAAGAVGPPGS 2719
Query: 877 SLADPAAE-----DEGDGSPAGAEDS---LEEEASSEGEPRVGLGFFYKDE--DKPEDEM 926
A+P++ G AG +D + S P +G G F D+ +P
Sbjct: 2720 WGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPA 2779
Query: 927 AQKRASLLERQ---------QRRAEEARRRKQWQEVEKEQRREEAARLAQEEA------- 970
+ RQ QR Q Q+ + Q+++ A + A
Sbjct: 2780 TPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPS 2839
Query: 971 -PGP--------APLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDL 1021
PGP +PL ++T P P GP + ++L ++
Sbjct: 2840 TPGPELGRQALGSPLAG---ISTRLPGPGEPVPGPAGPAQ------------FIELRHNV 2884
Query: 1022 DKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLST 1081
K L P G+ PG+G + R D LA RGL S L S
Sbjct: 2885 QKGLGP--GGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPP-QKPSAPPAPE 2941
Query: 1082 VANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRE 1116
+ N H K PT P+GL +R P S E
Sbjct: 2942 LNNSLHPTPHTKGPT----LPTGLELVNRPPSSTE 2972
Score = 38.9 bits (89), Expect = 0.032
Identities = 94/373 (25%), Positives = 127/373 (34%), Gaps = 51/373 (13%)
Query: 369 PPQNNSGSSSPVFTFRHPLL--SSGGPQSPLRGSTGSLKSSPSMSHMEALGKAWNRQLSR 426
PP+ N PV P S GP SP+ + SP + H + Q S
Sbjct: 985 PPEANCTDPEPVPPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSP 1044
Query: 427 PLSQAVSFSTPFGLDSDVDVV-MGDPVLLRSVSSDSLGPPR-PAPARTPTQPPPEP-GDL 483
P A+ S P L VV + D L + ++ + P PA + T P P P GDL
Sbjct: 1045 P---ALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPALEPSATSPLPSPMGDL 1101
Query: 484 ----PTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDR 539
P+ AL P D P G + SLAS S L D
Sbjct: 1102 SCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEP-GQTPGSLASELKG---SPVLLDP 1157
Query: 540 PTKAPV-----YMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSF 594
APV Y +T + SPC E +P AP +P + S +E+ S
Sbjct: 1158 EELAPVTPMEVYPECKQTAGQGSPC--EEQEEPRAPVAPTPPTLIKSDIV--NEISNLS- 1212
Query: 595 AERKKQLVKAEAEAGAGSPTSTPA----PPEALSSEMSELSARLEEKRRAIEAQKRRIEA 650
+ +A A P S P PE S EL + E R
Sbjct: 1213 ----------QGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDEGSLRLCTD 1262
Query: 651 IFAKHRQRLGKSAFLQVQPREASGE--------AEAEAEEADSGPVPGGERPAG---EGQ 699
+ L A + +A GE A + ++ S PG RP G G+
Sbjct: 1263 SLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRPRGGAHGGR 1322
Query: 700 GEPTSRPKAVTFS 712
G +R K+ S
Sbjct: 1323 GRGRARLKSTASS 1335
Score = 38.9 bits (89), Expect = 0.032
Identities = 97/466 (20%), Positives = 157/466 (33%), Gaps = 83/466 (17%)
Query: 504 GAADGSFYLHSPEGPSKPSLA-SPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVG 562
G + S L SP+ + +A P +P + S P + + + P +
Sbjct: 3976 GLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSS 4035
Query: 563 EASKPPAPSEGSPKAVASSP---AATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA- 618
EA++ P+ +G P A+ ++P A EVK + + + LV+ + + P+S
Sbjct: 4036 EATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQP---QPSSLQLQ 4092
Query: 619 PPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEA 678
PP L + + + L Q + + L QP + G+
Sbjct: 4093 PPLRLPGQQQQQVSLLHTAGGGSHGQ------LGSGSSSEASSVPHLLAQPSVSLGDQPG 4146
Query: 679 EAEEADSGPV-PGGERPAGEGQGEPTSRPKAVTFS----PDLGPVPHEG-LGEYNRAVSK 732
+ GP P ERP G +P V S P +G +P G L + V
Sbjct: 4147 SMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLA 4206
Query: 733 LSAALSSL----QRDMQRLTDQQQ-------RLLAP------------------------ 757
+ L L Q+ +Q L Q+Q R P
Sbjct: 4207 KNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF 4266
Query: 758 ----------------PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGP 801
P+ P P P + GP GP +P P+ R P
Sbjct: 4267 PGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKR------P 4320
Query: 802 SQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPP 861
SQ P SP P E +L P P P + SP+ + + L ++ P
Sbjct: 4321 SQLP-SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQL---ADTLFSKGLGP 4376
Query: 862 EEPAARPGLIEIPLGSLADPAAEDEGDGS--PAGAEDSLEEEASSE 905
+P + P S P D+ +G P ++ S+++E E
Sbjct: 4377 WDPPDNLAETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREE 4422
Score = 38.1 bits (87), Expect = 0.054
Identities = 102/466 (21%), Positives = 147/466 (31%), Gaps = 91/466 (19%)
Query: 477 PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPL 536
PP+PG L + A A P + + S +G KP S P+ +
Sbjct: 2107 PPQPGALGSPPPA------AAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELF 2160
Query: 537 SDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAE 596
P + P +P + P +P E P AP P P+ T A
Sbjct: 2161 LKLPPQVPAQVPSQD-PFGLAPAYPLEPRFPTAPPTYPPY-----PSPTG--------AP 2206
Query: 597 RKKQLVKAEAEAGAGSPTST-PAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKH 655
+ ++ A + GAG P PP + S L+ + +++
Sbjct: 2207 AQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLD------------- 2253
Query: 656 RQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGE-RPAGEGQGEPTSRPKAVTFSPD 714
+ E+ G +A E P P GE R A E + E P+
Sbjct: 2254 ----------NLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPN 2303
Query: 715 LGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPG-----SAPPPAA 769
LG V G + L D+ + + P++PG PPPA
Sbjct: 2304 LGFVDSPSSGTH-------LGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQ 2356
Query: 770 WVIPGPTTGPKAASP----SPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVL 825
+ P P + P P P + P T R P P P + P++ P +RV
Sbjct: 2357 ALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSD----PFSRVP 2412
Query: 826 TPPHDVDSLP--------HLRKFSPSQVPVQTRSSILLAEETPPEEPAAR---------- 867
P S F PS PV R PP P +R
Sbjct: 2413 ASPQSQSSSQSPLTPRPLSAEAFCPS--PVTPRFQSPDPYSRPPSRPQSRDPFAPLHKPP 2470
Query: 868 ---PGLIEIPLGSLADPAAEDEG--DGSPAGAEDSLEEEASSEGEP 908
P + GSLA + G PAG L + S G+P
Sbjct: 2471 RPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPS-GQP 2515
Score = 36.2 bits (82), Expect = 0.21
Identities = 47/220 (21%), Positives = 77/220 (35%), Gaps = 27/220 (12%)
Query: 917 KDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAPL 976
+ + K + ++ Q R E AE +++Q Q+ +++Q+++ +A LA + P L
Sbjct: 3569 EQQSKIQKQLDQVRKQQKEHTNLMAEYRNKQQQQQQQQQQQQQQHSAVLALSPSQSPRLL 3628
Query: 977 VSAVPMATPA----PAARAPAEEEVGPRK------------GDFTRQEYERRAQLKLMDD 1020
P P P + G R G F ++ Q +
Sbjct: 3629 TKLPGQLLPGHGLQPPQGPPGGQAGGLRLTPGGMALPGQPGGPFLNTALAQQQQQQHSGG 3688
Query: 1021 LDKVLRPRAAGSGG--PGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQST-- 1076
+ P SGG PG R+ P S + L R L +L + Q
Sbjct: 3689 AGSLAGP----SGGFFPGNLALRSLGPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQ 3744
Query: 1077 ---LSLSTVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPG 1113
L + + GV+ + P P GLM PS G
Sbjct: 3745 QHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMPPSSHQG 3784
Score = 33.5 bits (75), Expect = 1.3
Identities = 71/296 (23%), Positives = 101/296 (34%), Gaps = 71/296 (23%)
Query: 327 KVNLVVMLAELFMCFEVLKPDFVQVKDLPDGHAASPRGTEASPPQNNSGSSSPVFTFRHP 386
++N V AE + + D + D P H P P GS P P
Sbjct: 2072 RINKVQKQAESQINKQTKVGDIARKTDRPALHLRIP------PQPGALGSPPPAAA---P 2122
Query: 387 LLSSGGPQSPLRGST---GSLKS-SPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDS 442
+ G P +P ST G LK + S+ ++ G+ + + L + V PFGL
Sbjct: 2123 TIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLK-LPPQVPAQVPSQDPFGL-- 2179
Query: 443 DVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLP 502
P+ R ++ PP P+P P QPP + A R P
Sbjct: 2180 ----APAYPLEPRFPTAPPTYPPYPSPTGAPAQPP---------------MLGASSR--P 2218
Query: 503 DGAADGSFYLHSPEGP-SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLV 561
G F+ P P +PS P+L P PS +
Sbjct: 2219 GAGQPGEFHTTPPGTPRHQPSTPDPFL--------------------KPRCPS------L 2252
Query: 562 GEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTP 617
+ P +P G K AS P + F E +K L + E GA SP+ P
Sbjct: 2253 DNLAVPESPGVGGGK--ASEPL-----LSPPPFGESRKALEVKKEELGASSPSYGP 2301
Score = 33.1 bits (74), Expect = 1.7
Identities = 44/154 (28%), Positives = 55/154 (35%), Gaps = 19/154 (12%)
Query: 759 EAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAE--- 815
E P PP + + P P P + P +R P P S P + +RP E
Sbjct: 437 EMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPA---SPLPEALHLSRPLEESP 493
Query: 816 LRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPL 875
L P L+PP P FSP + S + EE+PP PA L P
Sbjct: 494 LSPPPEESPLSPP------PESSPFSPLE-----ESPLSPPEESPP-SPALETPLSPPPE 541
Query: 876 GS-LADPAAEDEGDGSPAGAEDSLEEEASSEGEP 908
S L+ P E P S EAS P
Sbjct: 542 ASPLSPPFEESPLSPPPEELPTSPPPEASRLSPP 575
Score = 33.1 bits (74), Expect = 1.7
Identities = 47/172 (27%), Positives = 58/172 (33%), Gaps = 33/172 (19%)
Query: 743 DMQRLTDQQQRLLAPPEAPGS--APPPAAW---VIPGPTTGPKAASPSPARRVPATRRSP 797
D+ R TD+ L P PG+ +PPPAA I PTT ++ + P P
Sbjct: 2092 DIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVP 2151
Query: 798 GPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAE 857
GP P EL L PP P+QVP Q + A
Sbjct: 2152 GPDS-----------PGELFLK------LPPQ-----------VPAQVPSQDPFGLAPAY 2183
Query: 858 ETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPR 909
P P A P P + A G S GA E + G PR
Sbjct: 2184 PLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPR 2235
Score = 32.7 bits (73), Expect = 2.3
Identities = 43/155 (27%), Positives = 55/155 (35%), Gaps = 18/155 (11%)
Query: 357 GHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEAL 416
G P+G P + S+ PV HP PQ P R S L S S EA
Sbjct: 4278 GAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPS--QLPSPSSQLPTEAQ 4335
Query: 417 GKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQP 476
+ +P Q + P G S + D ++ S LGP P TQ
Sbjct: 4336 LPPTHPGTPKP--QGPTLEPPPGRVSPAAAQLAD-----TLFSKGLGPWDPPDNLAETQK 4388
Query: 477 PPE----PGDL-----PTIEEALQIIHSAEPRLLP 502
P + PG L + EA Q+ EPR P
Sbjct: 4389 PEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEP 4423
Score = 31.6 bits (70), Expect = 5.1
Identities = 21/65 (32%), Positives = 24/65 (36%), Gaps = 5/65 (7%)
Query: 749 DQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSP 808
D +Q PPE P P P A P T P P+ P P P P SP
Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEP-----PVPSPLPLASSP 4956
Query: 809 KHTRP 813
+ RP
Sbjct: 4957 ESARP 4961
Score = 31.6 bits (70), Expect = 5.1
Identities = 15/32 (46%), Positives = 17/32 (53%)
Query: 965 LAQEEAPGPAPLVSAVPMATPAPAARAPAEEE 996
LA+ P P PL S+ A P P AR P E E
Sbjct: 4941 LAEPPVPSPLPLASSPESARPKPRARPPEEGE 4972
Score = 30.8 bits (68), Expect = 8.6
Identities = 15/86 (17%), Positives = 47/86 (54%), Gaps = 1/86 (1%)
Query: 884 EDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEE 943
+ + GS AG + S G+P++ + + + Q++ L ++QQ++ ++
Sbjct: 3863 QHQQQGSMAGLSHLQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQ 3922
Query: 944 ARRRKQWQEVEKEQRREEAARLAQEE 969
++ +Q Q+++++Q++++ + Q++
Sbjct: 3923 QQQLQQ-QQLQQQQQQQQLQQQQQQQ 3947
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 68.9 bits (167), Expect = 3e-11
Identities = 112/546 (20%), Positives = 206/546 (37%), Gaps = 56/546 (10%)
Query: 538 DRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAER 597
+ TK+P +P K + V E +K PA ++ K A SPA S K S A+
Sbjct: 498 EEETKSPP-AEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 598 KKQL---VKAEAEAGAGSPTSTPAPPEALSSEMSE----LSARLEEKRRAIEAQKRRIEA 650
+ + K+ + A SP +P +A S E A+ EK ++ ++ + A
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 651 IFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVT 710
+ KS P +A + EA+ + P E+ + + S KA
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP--EKEEAKSPEKAKSPVKAEA 674
Query: 711 FSPDLGPVPHEGLGEY-NRAVSKLSAALSSLQRDMQRLTDQ---QQRLLAPPEAPGSAPP 766
SP+ P + + +A S + S ++ + ++ ++ +P + P
Sbjct: 675 KSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPE 734
Query: 767 PAAWVIPGPTTGP-KAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVL 825
A + P KA SP A+ + + RSP P + + V
Sbjct: 735 KAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVK 794
Query: 826 TPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAED 885
+P L K ++P + + EE P+ E+ + A E+
Sbjct: 795 SPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQ---------EVKVKEPPKKAEEE 845
Query: 886 EGDGSPAGAE--DSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAE- 942
+ +P E DS +EEA + P+ K E+K E + + + S +E ++ AE
Sbjct: 846 KAPATPKTEEKKDSKKEEAPKKEAPKP------KVEEKKEPAVEKPKESKVEAKKEEAED 899
Query: 943 ---------EARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAARAPA 993
EA + + +E K + + E A+ ++A P + PA A A
Sbjct: 900 KKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEP-------SKPAEKKEA-A 951
Query: 994 EEEVGPRKGDFTRQEYERRAQLKLMDDLDKVL-----RPRAAGSGGPGRGGRRATRPRSG 1048
E+ ++ + E + + + K +D DK L +P+A + ++ ++P
Sbjct: 952 PEKKDTKEEKAKKPEEKPKTEAKAKED-DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEK 1010
Query: 1049 CCDDSA 1054
+D A
Sbjct: 1011 ATEDKA 1016
Score = 64.7 bits (156), Expect = 5e-10
Identities = 95/412 (23%), Positives = 157/412 (38%), Gaps = 48/412 (11%)
Query: 595 AERKKQLVKAEAEAGAGS-PTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFA 653
A +K L E G G P S P + S + + + EEK + +E ++ E +
Sbjct: 400 AAYRKLLEGEECRIGFGPIPFSLPEGLPKIPSVSTHIKVKSEEKIKVVEKSEK--ETVIV 457
Query: 654 KHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSP 713
+ ++ QV E + E E EA+E + GGE EG E T P A
Sbjct: 458 EE-----QTEETQV-TEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPA----- 506
Query: 714 DLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIP 773
E A S + S + + ++ + A ++P A PA
Sbjct: 507 ------EEAASPEKEAKSPVKEEAKS-PAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 774 GPTTGPKAASPSPAR-RVPATRRSPGPGPS---QSPRSPKHTRPAELRLAPLTRVLTPPH 829
P P+A SP + PA +SP S + +SP + E +P+ P
Sbjct: 560 SP---PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA 616
Query: 830 DVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDG 889
+ S SP++V ++ EE E A P E E
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSP---------------EKEEAK 661
Query: 890 SPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQ 949
SP A+ ++ EA S + + + K +K + + ++ S + + EEA+ ++
Sbjct: 662 SPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEK 721
Query: 950 WQEVEKEQRR--EEAARLAQEEAPGPAPLVS---AVPMATPAPAARAPAEEE 996
+ KE+ + E+A +EEA P S A + +P A+ PA+EE
Sbjct: 722 AKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEE 773
Score = 59.3 bits (142), Expect = 2e-08
Identities = 101/470 (21%), Positives = 173/470 (36%), Gaps = 55/470 (11%)
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
SPE S A PE P + K+P PE P V E +K PA ++
Sbjct: 566 SPEKEEAKSPAEVKSPEKAKSPAKEE-AKSPAEAKSPEKAKSP----VKEEAKSPAEAKS 620
Query: 574 SPKAVASSPAATNSEVKMTS---------------------FAERKKQLVKAEAEA--GA 610
K A SPA S K S E+ K VKAEA++ A
Sbjct: 621 PVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKA 680
Query: 611 GSPTSTPA-PPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFA--KHRQRLGKSAFLQV 667
SP A PE S + E + E+ + ++ + + E + K + + A V
Sbjct: 681 KSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPV 740
Query: 668 QPREASGEAEAEAEEADSGPV--PGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGE 725
+ S E E+A + V P + PA E P + SP E +
Sbjct: 741 KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSP-----VKEEVKS 795
Query: 726 YNRAVSKLSAALSSLQRDMQRLTDQQQRLL---APPEAPGSAPPPAAWVIPGPTTGPKAA 782
+A S L + ++++ + + + + P E PP A P T PK
Sbjct: 796 PEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPAT-PKTE 854
Query: 783 SPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSP 842
+++ A ++ + + P +P E ++ D +P K +P
Sbjct: 855 EKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKE---EAEDKKKVPTPEKEAP 911
Query: 843 SQVPV----QTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSL 898
++V V + + +A++ P + A P + A P +D + E+
Sbjct: 912 AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPS--KPAEKKEAAPEKKDTKEEKAKKPEEKP 969
Query: 899 EEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRK 948
+ EA ++ + + K+ KP+ E A+K +S ++ + E+A K
Sbjct: 970 KTEAKAKEDDKT----LSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 37.7 bits (86), Expect = 0.071
Identities = 64/294 (21%), Positives = 111/294 (37%), Gaps = 38/294 (12%)
Query: 895 EDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVE 954
E + EE + E E K+E+ E+E ++ + ++ ++ A ++
Sbjct: 463 ETQVTEEVTEEEEKEA------KEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEA 516
Query: 955 KEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEV--GPRKGDFTRQEYERR 1012
K +EEA A+ ++P S + +P A++PA+EE P ++E +
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSP-EKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 1013 AQLKLMDDLDKVLRPRAAGSGGPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIY 1072
A++K +K P + P A P A+SPA
Sbjct: 576 AEVK---SPEKAKSPAKEEAKSPA----EAKSPEKAKSPVKEEAKSPAE----------- 617
Query: 1073 SQSTLSLSTVANEAHNNLGVKRP-TSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASV 1131
+ S V EA + VK P +++P+ SP + + + ++ A SP
Sbjct: 618 -----AKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 1132 PEYTGPRLYKEPSAKSNKFIIHNALSHCCLAGKVNEPQKNRILEEI---EKSKA 1182
E P K P K+ A S K E K+ + EE EK+K+
Sbjct: 673 -EAKSPEKAKSP-VKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKS 724
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 67.0 bits (162), Expect = 1e-10
Identities = 129/608 (21%), Positives = 202/608 (33%), Gaps = 102/608 (16%)
Query: 458 SSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHS-----------------AEPRL 500
+SD L P+P P P +P PE E+ S PR
Sbjct: 241 TSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR 300
Query: 501 LPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCL 560
+ P +PS P P R +++PV + S
Sbjct: 301 RHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSS 360
Query: 561 VGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPP 620
+S+ +P + PK +S P T S R+ + SP +TP PP
Sbjct: 361 SSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR----------PSPPATP-PP 409
Query: 621 EALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAE-AE 679
+ S + S R + R + R KH+ G P + E +E
Sbjct: 410 KTRHSPTPQQSNRTRKSR--VSVSPGRTSGKVTKHK---GTEKRESPSPAPKPRKVELSE 464
Query: 680 AEEADSGPVPGGE---------RPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAV 730
+EE G + + R + + S + P V + +G R
Sbjct: 465 SEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHS 524
Query: 731 SKLSAALSSLQRDMQRL-TDQQQRLLAPP-----EAPGSAPPPAAWVIPGPTTGPKAASP 784
SA+ S +R + +++R +PP +P APPP P P + SP
Sbjct: 525 PSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSP 584
Query: 785 SPARRVPATRR---------SPGPGPSQSPRSP------------------KHTRPAELR 817
P RR P+ RR SP P P + SP H+ P + R
Sbjct: 585 PPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQR 644
Query: 818 LAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGS 877
+P+T+ +P S H + SPS+ + RS +P P A P S
Sbjct: 645 SSPVTKRRSPSL---SSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA-------PQTS 694
Query: 878 LADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQ 937
+ P SP + S P + PE + +K AS +
Sbjct: 695 SSPPPVRRGASSSP-----QRRQSPSPSTRP------IRRVSRTPEPKKIKKAASPSPQS 743
Query: 938 QRRAEEARRRKQWQEVEKEQRREEAARLAQEEAP----GPAPLVSAVPMATPAPAARAPA 993
RR +R E ++ + + Q ++P PA V TP+P+ +
Sbjct: 744 VRRVSSSRSVSGSPEPAAKKPPAPPSPV-QSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802
Query: 994 EEEVGPRK 1001
++E G +K
Sbjct: 803 DQEGGGKK 810
Score = 60.1 bits (144), Expect = 1e-08
Identities = 128/602 (21%), Positives = 212/602 (35%), Gaps = 94/602 (15%)
Query: 456 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSP 515
S SS S PP+ P RT + P + ++ SA P
Sbjct: 362 SSSSRSRSPPKKPPKRTSSPP----------RKTRRLSPSASPP-------------RRR 398
Query: 516 EGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSP 575
PS P+ P + S+R K+ V + T K + E + P+P+ P
Sbjct: 399 HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP-KP 457
Query: 576 KAVASSPAATNSEVKMTSF------AERKKQLVKAEAEAGAGSPTSTPAPPEA------- 622
+ V S + + KM + + ++Q ++ +++G+ S + P +
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEV 517
Query: 623 ------LSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEA 676
S + S R +K + ++RR + R+R A PR
Sbjct: 518 GRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPA---PPPRRRRTPT 574
Query: 677 EAEAEEADS------GPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAV 730
S P P P + + P+ PK T SP P P
Sbjct: 575 PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPP--PPPKRRASPSPPPK 632
Query: 731 SKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRV 790
++S + QR +T ++ L+ GS+P + P K SPSP R
Sbjct: 633 RRVSHSPPPKQRS-SPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN-KRHSPSPRPRA 690
Query: 791 PATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTR 850
P T SP P + SP+ + P+ RV P + + SPS V+
Sbjct: 691 PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTP---EPKKIKKAASPSPQSVRRV 747
Query: 851 SSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRV 910
SS +P EPAA+ PA + S+ P V
Sbjct: 748 SSSRSVSGSP--EPAAKK---------------------PPAPPSPVQSQSPSTNWSPAV 784
Query: 911 GLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEA 970
+ K P + R S Q + +++K+ ++ +K+++ ++ + +E+A
Sbjct: 785 PV----KKAKSPTPSPSPPRNS----DQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKA 836
Query: 971 PGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRAA 1030
A + P A A EE V + ++E E A+ L DDL+K LR +A
Sbjct: 837 VAAAAAAAVTPAAIAAATTTLAQEEPVAAPE---PKKETESEAEDNL-DDLEKHLREKAL 892
Query: 1031 GS 1032
S
Sbjct: 893 RS 894
Score = 33.5 bits (75), Expect = 1.3
Identities = 60/292 (20%), Positives = 112/292 (38%), Gaps = 39/292 (13%)
Query: 882 AAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYK-DEDKPEDEMAQKRASLLERQQRR 940
+A++ G P+ + +EE + L K DEDK + + +K +S +R++ R
Sbjct: 111 SAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSR 170
Query: 941 AEEARR------RKQWQEVEKEQRREEAA---RLAQEEAPGPAPLVSAVPMATPAPAARA 991
+ R+ R++ V +E++R + + +P PAP P P+ +
Sbjct: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKV 230
Query: 992 PAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPR--AAGSGGPGRGGRRATRPRSGC 1049
E V QE + + + + + P+ + + TRPRS
Sbjct: 231 -KEPSV---------QEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRS 280
Query: 1050 CDDSALARSPARGLLGSRLSKIYSQSTLSLSTVANEAHNNLGVKRPTSRAPSPSGLMSP- 1108
S +R+ +R +R + + + S S + +RP+ R +P M P
Sbjct: 281 RSKSR-SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR----RRPSPRRRTPPRRMPPP 335
Query: 1109 -----SRLPGSRER------DWENGSNASSPASVPEYTGPRLYKEPSAKSNK 1149
SR P R R + S++SS + P P+ P K+ +
Sbjct: 336 PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRR 387
Score = 32.7 bits (73), Expect = 2.3
Identities = 26/120 (21%), Positives = 46/120 (38%), Gaps = 7/120 (5%)
Query: 749 DQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSP 808
++++R +P +P P P ++ S SP R + RSP P P + ++P
Sbjct: 164 EKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKS--RSPSPAPEKKEKTP 221
Query: 809 KHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARP 868
+ P+ P + T D+ +P P +P S + E+ RP
Sbjct: 222 ELPEPSVKVKEPSVQEATSTSDILKVP-----KPEPIPEPKEPSPEKNSKKEKEKEKTRP 276
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 66.6 bits (161), Expect = 1e-10
Identities = 169/790 (21%), Positives = 261/790 (33%), Gaps = 181/790 (22%)
Query: 357 GHAASPRGTEASPPQNNSGSSSPVF----TFRHPLLSSG---------GPQSPLRGSTGS 403
GH S G A PP SG + P+ T + P+ G GP P TGS
Sbjct: 320 GHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378
Query: 404 LKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLG 463
K S +AL ++P + + G +G P L
Sbjct: 379 EKPSSEQPGPKAL--------AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 464 PPRPAPARTPTQPPPEPGDLPTIE------EALQIIHSAEPRLLPDGAADGSFYLHSPEG 517
P P +TP Q P PG +P + A Q + P LP A G
Sbjct: 431 AKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQPG 485
Query: 518 PSKPSLASPYLPEGTSKPLSDRP--TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSP 575
P+KP P G++KP S +P TK P P P PS P ++KPP+ GS
Sbjct: 486 PAKPPPQQP----GSAKPPSQQPGSTKPPPQQPGPAKPSPQQP----GSTKPPSQQPGSA 537
Query: 576 KAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA--------PPEALSSEM 627
K A P+ +Q K ++ G+G P P P + L +
Sbjct: 538 KPSAQQPSPAKPSA---------QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Query: 628 ------SELSARLEEKRRAIEAQKRRIEAIFA------KHRQRLGKSAFLQVQPREASGE 675
+EL + EK + + H + + L Q + A G
Sbjct: 589 CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG- 647
Query: 676 AEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSA 735
D PVP +P + + P + AV+ S P P +
Sbjct: 648 -------GDLAPVPSSPQP--KLKTAPVTTTSAVSKS---SPQPQQ-------------- 681
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR 795
+S ++D AP + AP P P P + P
Sbjct: 682 --TSPKKD-----------AAPKQDLSKAPEP--------------KKPPPLVKQPTLHG 714
Query: 796 SPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILL 855
SP Q P + ++PA + + P + D P + P Q + ++ L+
Sbjct: 715 SPSAKAKQPPEADSLSKPAP------PKEPSVPSEQDKAP-VADDKPKQPKMVKPTTDLV 767
Query: 856 AEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFF 915
+ + +P +IP + A E +P DS + S+ P G
Sbjct: 768 SSSSATTKP-------DIPSSKVQSQAEEKT---TPPLKTDSAK---PSQSFPPTG---- 810
Query: 916 YKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAP 975
++ P D A R + + + K ++V+ Q++EE + + +P P
Sbjct: 811 --EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD- 867
Query: 976 LVSAVPMATPAPAARAPAEEEVGPRKGDFTR-QEYERRAQLKLMDDLDKVLRPRAAGSGG 1034
+P +P P P + P + QE RR L L
Sbjct: 868 -AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL----------------- 909
Query: 1035 PGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLSTVANEA-HNNLGVK 1093
G P+S + G L + I+SQ++ +ST H+ G
Sbjct: 910 ----GSITDAPKS----QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 1094 RPTSRAPSPS 1103
P +AP+PS
Sbjct: 962 APMKQAPAPS 971
Score = 53.1 bits (126), Expect = 2e-06
Identities = 110/517 (21%), Positives = 175/517 (33%), Gaps = 94/517 (18%)
Query: 346 PDFVQVKDLPDGHAASPRGTEASP---PQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTG 402
P + ++L H G P Q S TFR G +SP ST
Sbjct: 79 PSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPG--RSP---STI 133
Query: 403 SLKSSPSMS-----HMEALGKAWNRQLSR--PLSQAVSFSTPFGLDSDVDVVMGDPVLLR 455
SLK S S + H ++ + +++ +S V+ PF L SD + + +
Sbjct: 134 SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQ 193
Query: 456 SVSSDSLGPP----RPAPARTPTQPPPE---PGDLPTIEEAL-QIIHSAEPRLLPDGAAD 507
V G P +P + P +P P+ PG P ++ + I S +P +
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 508 GSFYLHSP--------------EGPSKPSLASPYLPEGTS-KPLSDRPTKAPVYMPHPET 552
+ P S+P + G S KP P+K P+ P P
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313
Query: 553 P---------SKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLV- 602
P S+P P +KPPA G K +A P V+ + Q +
Sbjct: 314 PPAQQPGHEKSQPGP------AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 603 ---KAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRL 659
+ G+ P+S P+AL+ ++ A ++ + L
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ------VGTPKPL 421
Query: 660 GKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVP 719
+ LQ P +A G + ++ G +P + G+ + T K + P P
Sbjct: 422 AQQPGLQ-SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 720 HEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPP-EAPGSAPPPAAWVIPGPTTG 778
+ G + QQ PP + PGS PP PGP
Sbjct: 481 PQQPGP-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQ--PGP--- 516
Query: 779 PKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAE 815
A PSP + P + + P P + S + PA+
Sbjct: 517 ---AKPSPQQ--PGSTKPPSQQPGSAKPSAQQPSPAK 548
Score = 44.7 bits (104), Expect = 6e-04
Identities = 89/419 (21%), Positives = 140/419 (33%), Gaps = 71/419 (16%)
Query: 451 PVLLRSVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSF 510
PV S S S P+ + P + P ++ P L+ GS
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP--------PPLVKQPTLHGSP 716
Query: 511 YLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPS--KPSPCLVGEASKPP 568
+ + P SL+ P P+ S P KAPV P+ P KP+ LV +S
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVP--SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 569 APSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMS 628
P S K + + T +K S + Q E + + P + S +S
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 629 ELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSG-P 687
E K + ++++ + K K A ++ P+ +A+ G P
Sbjct: 833 HPGPSSESKGQ------KQVDPVQKKEEP---KKAQTKMSPKP-------DAKPMPKGSP 876
Query: 688 VPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
P G RP GQ PT P P P E ++ + ++
Sbjct: 877 TPPGPRPTA-GQTVPT---------PQQSPKPQEQSRRFSLNLGSIT------------- 913
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRS 807
+AP S P + G G A+ S A + +T PGP P +
Sbjct: 914 -----------DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
Query: 808 PKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAA 866
P PA + P ++ PP P +PV+ + AE+ P+ A
Sbjct: 963 PMKQAPAPSQ-PPTSQ--GPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 41.6 bits (96), Expect = 0.005
Identities = 112/573 (19%), Positives = 206/573 (35%), Gaps = 67/573 (11%)
Query: 469 PARTPTQPPPEPGDLP-TIEEALQIIHSAEPRLLPDGAA-----DGSFYLHSPEGPSKPS 522
P+ TP P E TI+E Q +A+P + G D S + P P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358
Query: 523 LASP--YLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVAS 580
S Y +G S L + P+ P K S+ +PS S A
Sbjct: 1359 GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-----SFSQESSPSSPSDLAKLE 1413
Query: 581 SPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS---TPAPPEALSSEMSELSARLEEK 637
S + E + ++ A+ K + E P T + E L +SE + ++
Sbjct: 1414 STVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 638 RRAIEAQKRRIEAIFAKHRQRLGKSAFLQ-VQPREASGEAEAEAEEADSGPVPGGERPA- 695
R + K+ + + KS F+ + R ++ E+ E+++ PVP +R
Sbjct: 1474 ERK-DTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
Query: 696 ---------------GEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 740
G G+ E R + + S D E + ++S++ S
Sbjct: 1533 VGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQ 1592
Query: 741 QRDMQR----LTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRS 796
+++ + +T + R L + S A +A SP + T+
Sbjct: 1593 KKEETKGKGKITAGKHRRLTRKSST-SIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 797 P--------GPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPV- 847
G G + ++ A+ A ++ T + D P L S + P
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLY-FDEEPELEMESLTDSPED 1710
Query: 848 ----QTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEAS 903
+ SS+ + TP P + L +++ D SP+ + +++
Sbjct: 1711 RSRGEGSSSLHASSFTPGTSPTSVSSL-------------DEDSDSSPSHKKGESKQQRK 1757
Query: 904 SEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAA 963
+ P L +D + E+E+ ++ L E++++R E ++RK + K+ + E A
Sbjct: 1758 ARHRPHGPLLPTIEDSSE-EEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRA 1816
Query: 964 RLAQEEAPGPAPLVSAVPMATPAPAARAPAEEE 996
+ +E P +S + A+P R AE E
Sbjct: 1817 QRRRERPKTPPSNLSPIEDASPTEELRQAAEME 1849
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/185 (26%), Positives = 68/185 (36%), Gaps = 32/185 (17%)
Query: 457 VSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPE 516
+S+ PP P P P PPP P LP S +P +LP + SP
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT-------SPKPTILP----KKKLTVASPV 2449
Query: 517 GPSKP------SLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVG-------E 563
+ P +L + + P++ T AP P P KPS G E
Sbjct: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSSIPSGLVFTHRPE 2504
Query: 564 ASKPP-APSEGSPKAVASSPAATNSEVKMTSFAERKKQLVK--AEAEAGAGSPTSTPAPP 620
SKPP AP P+ ++ T+ K T + + A+ SPTS +P
Sbjct: 2505 PSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPH 2564
Query: 621 EALSS 625
SS
Sbjct: 2565 SNKSS 2569
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 66.6 bits (161), Expect = 1e-10
Identities = 169/790 (21%), Positives = 261/790 (33%), Gaps = 181/790 (22%)
Query: 357 GHAASPRGTEASPPQNNSGSSSPVF----TFRHPLLSSG---------GPQSPLRGSTGS 403
GH S G A PP SG + P+ T + P+ G GP P TGS
Sbjct: 320 GHEKSQPGP-AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGS 378
Query: 404 LKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLG 463
K S +AL ++P + + G +G P L
Sbjct: 379 EKPSSEQPGPKAL--------AQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSP 430
Query: 464 PPRPAPARTPTQPPPEPGDLPTIE------EALQIIHSAEPRLLPDGAADGSFYLHSPEG 517
P P +TP Q P PG +P + A Q + P LP A G
Sbjct: 431 AKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPP----QQPG 485
Query: 518 PSKPSLASPYLPEGTSKPLSDRP--TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSP 575
P+KP P G++KP S +P TK P P P PS P ++KPP+ GS
Sbjct: 486 PAKPPPQQP----GSAKPPSQQPGSTKPPPQQPGPAKPSPQQP----GSTKPPSQQPGSA 537
Query: 576 KAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA--------PPEALSSEM 627
K A P+ +Q K ++ G+G P P P + L +
Sbjct: 538 KPSAQQPSPAKPSA---------QQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTI 588
Query: 628 ------SELSARLEEKRRAIEAQKRRIEAIFA------KHRQRLGKSAFLQVQPREASGE 675
+EL + EK + + H + + L Q + A G
Sbjct: 589 CPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG- 647
Query: 676 AEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSA 735
D PVP +P + + P + AV+ S P P +
Sbjct: 648 -------GDLAPVPSSPQP--KLKTAPVTTTSAVSKS---SPQPQQ-------------- 681
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR 795
+S ++D AP + AP P P P + P
Sbjct: 682 --TSPKKD-----------AAPKQDLSKAPEP--------------KKPPPLVKQPTLHG 714
Query: 796 SPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILL 855
SP Q P + ++PA + + P + D P + P Q + ++ L+
Sbjct: 715 SPSAKAKQPPEADSLSKPAP------PKEPSVPSEQDKAP-VADDKPKQPKMVKPTTDLV 767
Query: 856 AEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFF 915
+ + +P +IP + A E +P DS + S+ P G
Sbjct: 768 SSSSATTKP-------DIPSSKVQSQAEEKT---TPPLKTDSAK---PSQSFPPTG---- 810
Query: 916 YKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAP 975
++ P D A R + + + K ++V+ Q++EE + + +P P
Sbjct: 811 --EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD- 867
Query: 976 LVSAVPMATPAPAARAPAEEEVGPRKGDFTR-QEYERRAQLKLMDDLDKVLRPRAAGSGG 1034
+P +P P P + P + QE RR L L
Sbjct: 868 -AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL----------------- 909
Query: 1035 PGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLSTVANEA-HNNLGVK 1093
G P+S + G L + I+SQ++ +ST H+ G
Sbjct: 910 ----GSITDAPKS----QPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPG 961
Query: 1094 RPTSRAPSPS 1103
P +AP+PS
Sbjct: 962 APMKQAPAPS 971
Score = 53.1 bits (126), Expect = 2e-06
Identities = 110/517 (21%), Positives = 175/517 (33%), Gaps = 94/517 (18%)
Query: 346 PDFVQVKDLPDGHAASPRGTEASP---PQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTG 402
P + ++L H G P Q S TFR G +SP ST
Sbjct: 79 PSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPG--RSP---STI 133
Query: 403 SLKSSPSMS-----HMEALGKAWNRQLSR--PLSQAVSFSTPFGLDSDVDVVMGDPVLLR 455
SLK S S + H ++ + +++ +S V+ PF L SD + + +
Sbjct: 134 SLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQ 193
Query: 456 SVSSDSLGPP----RPAPARTPTQPPPE---PGDLPTIEEAL-QIIHSAEPRLLPDGAAD 507
V G P +P + P +P P+ PG P ++ + I S +P +
Sbjct: 194 KVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPG 253
Query: 508 GSFYLHSP--------------EGPSKPSLASPYLPEGTS-KPLSDRPTKAPVYMPHPET 552
+ P S+P + G S KP P+K P+ P P
Sbjct: 254 TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGK 313
Query: 553 P---------SKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLV- 602
P S+P P +KPPA G K +A P V+ + Q +
Sbjct: 314 PPAQQPGHEKSQPGP------AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLG 367
Query: 603 ---KAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRL 659
+ G+ P+S P+AL+ ++ A ++ + L
Sbjct: 368 PAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQ------VGTPKPL 421
Query: 660 GKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVP 719
+ LQ P +A G + ++ G +P + G+ + T K + P P
Sbjct: 422 AQQPGLQ-SPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPP 480
Query: 720 HEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPP-EAPGSAPPPAAWVIPGPTTG 778
+ G + QQ PP + PGS PP PGP
Sbjct: 481 PQQPGP-------------------AKPPPQQPGSAKPPSQQPGSTKPPPQQ--PGP--- 516
Query: 779 PKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAE 815
A PSP + P + + P P + S + PA+
Sbjct: 517 ---AKPSPQQ--PGSTKPPSQQPGSAKPSAQQPSPAK 548
Score = 44.7 bits (104), Expect = 6e-04
Identities = 89/419 (21%), Positives = 140/419 (33%), Gaps = 71/419 (16%)
Query: 451 PVLLRSVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSF 510
PV S S S P+ + P + P ++ P L+ GS
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKP--------PPLVKQPTLHGSP 716
Query: 511 YLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPS--KPSPCLVGEASKPP 568
+ + P SL+ P P+ S P KAPV P+ P KP+ LV +S
Sbjct: 717 SAKAKQPPEADSLSKPAPPKEPSVP--SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATT 774
Query: 569 APSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMS 628
P S K + + T +K S + Q E + + P + S +S
Sbjct: 775 KPDIPSSKVQSQAEEKTTPPLKTDS--AKPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS 832
Query: 629 ELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSG-P 687
E K + ++++ + K K A ++ P+ +A+ G P
Sbjct: 833 HPGPSSESKGQ------KQVDPVQKKEEP---KKAQTKMSPKP-------DAKPMPKGSP 876
Query: 688 VPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
P G RP GQ PT P P P E ++ + ++
Sbjct: 877 TPPGPRPTA-GQTVPT---------PQQSPKPQEQSRRFSLNLGSIT------------- 913
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRS 807
+AP S P + G G A+ S A + +T PGP P +
Sbjct: 914 -----------DAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGA 962
Query: 808 PKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAA 866
P PA + P ++ PP P +PV+ + AE+ P+ A
Sbjct: 963 PMKQAPAPSQ-PPTSQ--GPPKSTGQAP---PAPAKSIPVKKETKAPAAEKLEPKAEQA 1015
Score = 41.6 bits (96), Expect = 0.005
Identities = 112/573 (19%), Positives = 206/573 (35%), Gaps = 67/573 (11%)
Query: 469 PARTPTQPPPEPGDLP-TIEEALQIIHSAEPRLLPDGAA-----DGSFYLHSPEGPSKPS 522
P+ TP P E TI+E Q +A+P + G D S + P P
Sbjct: 1299 PSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTEKEDDKSDTSSSQQPKSPQ 1358
Query: 523 LASP--YLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVAS 580
S Y +G S L + P+ P K S+ +PS S A
Sbjct: 1359 GLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKD-----SFSQESSPSSPSDLAKLE 1413
Query: 581 SPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS---TPAPPEALSSEMSELSARLEEK 637
S + E + ++ A+ K + E P T + E L +SE + ++
Sbjct: 1414 STVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETLEITISEEEIKESQE 1473
Query: 638 RRAIEAQKRRIEAIFAKHRQRLGKSAFLQ-VQPREASGEAEAEAEEADSGPVPGGERPA- 695
R + K+ + + KS F+ + R ++ E+ E+++ PVP +R
Sbjct: 1474 ERK-DTFKKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEESSESENSPVPQRKRRTS 1532
Query: 696 ---------------GEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 740
G G+ E R + + S D E + ++S++ S
Sbjct: 1533 VGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDEFIRNQLKEISSSTESQ 1592
Query: 741 QRDMQR----LTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRS 796
+++ + +T + R L + S A +A SP + T+
Sbjct: 1593 KKEETKGKGKITAGKHRRLTRKSST-SIDEDAGRRHSWHDEDDEAFDESPELKYRETKSQ 1651
Query: 797 P--------GPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPV- 847
G G + ++ A+ A ++ T + D P L S + P
Sbjct: 1652 ESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLY-FDEEPELEMESLTDSPED 1710
Query: 848 ----QTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEAS 903
+ SS+ + TP P + L +++ D SP+ + +++
Sbjct: 1711 RSRGEGSSSLHASSFTPGTSPTSVSSL-------------DEDSDSSPSHKKGESKQQRK 1757
Query: 904 SEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAA 963
+ P L +D + E+E+ ++ L E++++R E ++RK + K+ + E A
Sbjct: 1758 ARHRPHGPLLPTIEDSSE-EEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKDELRA 1816
Query: 964 RLAQEEAPGPAPLVSAVPMATPAPAARAPAEEE 996
+ +E P +S + A+P R AE E
Sbjct: 1817 QRRRERPKTPPSNLSPIEDASPTEELRQAAEME 1849
Score = 38.5 bits (88), Expect = 0.041
Identities = 49/185 (26%), Positives = 68/185 (36%), Gaps = 32/185 (17%)
Query: 457 VSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPE 516
+S+ PP P P P PPP P LP S +P +LP + SP
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT-------SPKPTILP----KKKLTVASPV 2449
Query: 517 GPSKP------SLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVG-------E 563
+ P +L + + P++ T AP P P KPS G E
Sbjct: 2450 TTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSSIPSGLVFTHRPE 2504
Query: 564 ASKPP-APSEGSPKAVASSPAATNSEVKMTSFAERKKQLVK--AEAEAGAGSPTSTPAPP 620
SKPP AP P+ ++ T+ K T + + A+ SPTS +P
Sbjct: 2505 PSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPH 2564
Query: 621 EALSS 625
SS
Sbjct: 2565 SNKSS 2569
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 65.5 bits (158), Expect = 3e-10
Identities = 76/273 (27%), Positives = 101/273 (36%), Gaps = 41/273 (15%)
Query: 669 PREASGEAEA--------EAEEADSGPVPGG------ERPAGEGQGEPTSRPKAVTF--S 712
P A+GEA +A A S P+P G ++P + + P+A T S
Sbjct: 608 PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPS 667
Query: 713 PDLGPVPHE-GLGEYNRAVSKLSAALSSLQ------RDMQRLTDQQQRLLAPPEAPGSAP 765
P L P + LG+ A SLQ R Q L+ + L P SAP
Sbjct: 668 PGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAP 727
Query: 766 PPAAWVIP------GPTTGPKA----ASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAE 815
PPA P G GP+A ASP+PA ++PA GPGPS SP P +
Sbjct: 728 PPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGD 787
Query: 816 LRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPL 875
P PP S P PS+ P L PP+ P PG+ I
Sbjct: 788 SPHLPSPHPTRPPSRPPSRPQSVSRPPSEPP--------LHPCPPPQAPPTLPGIFVIQN 839
Query: 876 GSLADPAAEDEGDGSPAGAEDSLEEEASSEGEP 908
P A + +P + L ++ P
Sbjct: 840 QLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGP 872
Score = 55.5 bits (132), Expect = 3e-07
Identities = 112/469 (23%), Positives = 168/469 (35%), Gaps = 62/469 (13%)
Query: 451 PVLLRSVSSDSLGPPRPA-PARTP-----TQPPPEPGDLPTIEEALQIIHSAEPRLLPDG 504
PV L + S + P PA PA T T PP L T + +Q A P
Sbjct: 558 PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQ---PATPAAATGE 614
Query: 505 AADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYM---PHPETPSKPSPCLV 561
AA +P+ P P++++P LP G +P + +P +AP P T +PSP
Sbjct: 615 AAPVLTVQPAPQAP--PAVSTP-LPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSP--- 668
Query: 562 GEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEA-EAGAGSPTSTPAPP 620
G AS P G P + + T ++M ER +Q + AE + APP
Sbjct: 669 GLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSVPASVIVSAPP 728
Query: 621 EALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEA 680
A A K + Q +A A Q + +A L+ +S +A
Sbjct: 729 PA----QDPAPATPVAKGAGLGPQAPDSQASPAPAPQ-IPAAAPLKGPGPSSSPSLPHQA 783
Query: 681 EEADSG--PVPGGERPAGEGQGEPTSRPKAVT---FSPDLGPVPHEGLGEYNRAVSKLSA 735
DS P P RP P SRP++V+ P L P P + +
Sbjct: 784 PLGDSPHLPSPHPTRPPSR----PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQN 839
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEAP--GSAPPPAAWVIPGPTTGPKAASPSPARRVPAT 793
L ++ PP+ P + PP + P P P + S + A +
Sbjct: 840 QLGV----PPPASNPAPTAPGPPQPPLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS 895
Query: 794 RRSPGPGPSQ-----SPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQ 848
R P P PS P H P TPP + +P +P P +
Sbjct: 896 SRLPAPTPSDFQLQFPPSQGPHKSP------------TPPPTLHLVP--EPAAPPPPPPR 941
Query: 849 TRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDS 897
T + P+ A ++P G + +++ G+PA + S
Sbjct: 942 TFQMVTTPFPALPQPKALLERFHQVPSGII----LQNKAGGAPAAPQTS 986
Score = 45.8 bits (107), Expect = 3e-04
Identities = 134/704 (19%), Positives = 216/704 (30%), Gaps = 93/704 (13%)
Query: 369 PPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAWNRQLSRPL 428
PPQ+ + V F P+ P+ G G SP + LG A + + +P+
Sbjct: 183 PPQDVVNKALSVQPFLQPVGLGNVTLQPIPGLQGLPNGSPGGATAATLGLAPIQVVGQPV 242
Query: 429 SQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEPG------- 481
L++ ++ V + + + GP P + P G
Sbjct: 243 ---------MALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGAGLVIQKNL 293
Query: 482 --DLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASP-YLPEGTSKPLSD 538
+ T + A P G G +P S P + +P + T P+
Sbjct: 294 SAAVATTLNGNSVFGGAGAASAPTGTPSGQPLAVAPGLGSSPLVPAPNVILHRTPTPIQP 353
Query: 539 RPT-----KAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTS 593
+P K P P P+ + + GE P + + V ++
Sbjct: 354 KPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKAGQNVVLSG 413
Query: 594 FAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFA 653
F Q + + + P PP ALS MS + + +
Sbjct: 414 FPAPALQANVFKQPPATTTGAAPPQPPGALSKPMS------------VHLLNQGSSIVIP 461
Query: 654 KHRQRLGKSAFLQVQPREASGEAEAEAEEAD-SGPVPGGERPAGEGQ--GEPTSRPKAVT 710
G++ FL + A A+ G + P GQ P + +
Sbjct: 462 AQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLA 521
Query: 711 FSPDLGPV--PHEG-------------LGEYNRAVSKLSAALSSLQRDMQ------RLTD 749
LGPV PH G +G+ +S A SL Q T
Sbjct: 522 GPLSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATT 581
Query: 750 QQQRLLAPPEAPGSAPPPAAWVIPG-PTTGPKAASP----SPARRVPATRRSPGPGPSQS 804
Q + PP A P V P P A+P PA + P +P P Q
Sbjct: 582 VLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQ 641
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP---P 861
P++ + + + A + TP K Q P T ++IL + P
Sbjct: 642 PQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLP 701
Query: 862 EEPAARPGLIEIPLGSL-------ADPAAEDEGDGSPAGAEDSL-----EEEASSEGEPR 909
+E + +P E P S+ A P A+D +P L + +AS P+
Sbjct: 702 QERSQQPLSAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761
Query: 910 VGLGFFYKDEDKPEDEMAQKRASL-----LERQQRRAEEARRRKQWQEVEKEQRREEAAR 964
+ K +A L L +R + Q V +
Sbjct: 762 IPAAAPLKGPGPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRPQSVSRPPSEPPLHP 821
Query: 965 LAQEEAPGPAPLVSAV--------PMATPAPAARAPAEEEVGPR 1000
+AP P + + P + PAP A P + + P+
Sbjct: 822 CPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQ 865
Score = 42.0 bits (97), Expect = 0.004
Identities = 69/298 (23%), Positives = 98/298 (32%), Gaps = 56/298 (18%)
Query: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGST---GSLKSSPSMSHMEALG 417
+P A+PPQ + SP + G P S + SL+ +
Sbjct: 650 APTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPL 709
Query: 418 KAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPP 477
A LS P S VS P D + L + DS P PAP P
Sbjct: 710 SAEGPHLSVPASVIVSAPPP-AQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPL 768
Query: 478 PEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLS 537
PG S+ P L S +L SP P++P P P+ S+P S
Sbjct: 769 KGPGP------------SSSPSLPHQAPLGDSPHLPSPH-PTRPPSRPPSRPQSVSRPPS 815
Query: 538 DRP------------------------TKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
+ P P P P P P P L ++ P P
Sbjct: 816 EPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPPEGPLPP 875
Query: 574 SP--------KAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEAL 623
+P AVASS + T+S + + ++ + Q ++ P +P PP L
Sbjct: 876 APHLPPSSTSSAVASS-SETSSRLPAPTPSDFQLQFPPSQ------GPHKSPTPPPTL 926
Score = 39.7 bits (91), Expect = 0.019
Identities = 77/319 (24%), Positives = 110/319 (34%), Gaps = 57/319 (17%)
Query: 350 QVKDLPDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPS 409
Q D A +P+ A+P + SSSP + PL S P P T PS
Sbjct: 748 QAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDS--PHLPSPHPTRPPSRPPS 805
Query: 410 MSHMEALGKAWNRQLSRPLSQAVSFSTP-----------FGLDSDVDVVMGDPVLLRSVS 458
+ +SRP S+ P F + + +G P + +
Sbjct: 806 RP----------QSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQ----LGVPPPASNPA 851
Query: 459 SDSLGPPRPAPARTPTQPP----PEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHS 514
+ GPP+P P R +QPP P LP + + S+E F L
Sbjct: 852 PTAPGPPQP-PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQF 910
Query: 515 P--EGPSKPSLASPYL---PEGTSKPLSDRPTKAPVYMPHPETPSK----------PSPC 559
P +GP K P L PE + P T V P P P PS
Sbjct: 911 PPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGI 970
Query: 560 LVGE--ASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGA-----GS 612
++ P AP + +SPAA+ V ++ A + A A A G
Sbjct: 971 ILQNKAGGAPAAPQTSTSLGPLTSPAAS---VLVSGQAPSGTPTAPSHAPAPAPMAATGL 1027
Query: 613 PTSTPAPPEALSSEMSELS 631
P PA +A +S + L+
Sbjct: 1028 PPLLPAENKAFASNLPTLN 1046
Score = 33.1 bits (74), Expect = 1.7
Identities = 46/206 (22%), Positives = 72/206 (34%), Gaps = 21/206 (10%)
Query: 356 DGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSP----LRGSTGSLKSSPSMS 411
+GH G +S S P + + G SP R S+ SS S S
Sbjct: 1217 EGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSSSSSS 1276
Query: 412 HMEALGKAWNRQL---SRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPA 468
+L + + +RP + + GL + G ++ + + D + P P
Sbjct: 1277 AASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQPPPP 1336
Query: 469 P-----ARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGP----S 519
P A P +PPP P + + A P P G A H P P
Sbjct: 1337 PATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP-----HCPRLPLRKTY 1391
Query: 520 KPSLASPYLPEGTSKPLSDRPTKAPV 545
+ ++ P PEGT + + AP+
Sbjct: 1392 RENVGGPGAPEGTPAGRARGGSPAPL 1417
Score = 32.7 bits (73), Expect = 2.3
Identities = 23/83 (27%), Positives = 33/83 (39%), Gaps = 1/83 (1%)
Query: 468 APARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPS-LASP 526
AP+ TPT P P P L + AE + + + GP KPS L
Sbjct: 1005 APSGTPTAPSHAPAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYE 1064
Query: 527 YLPEGTSKPLSDRPTKAPVYMPH 549
G KP + +P+K ++ H
Sbjct: 1065 SKLSGLKKPPTLQPSKEACFLEH 1087
>gi|155030232 proline, glutamic acid and leucine rich protein 1 [Homo
sapiens]
Length = 1130
Score = 63.2 bits (152), Expect = 2e-09
Identities = 80/322 (24%), Positives = 115/322 (35%), Gaps = 52/322 (16%)
Query: 688 VPGGERPAGEGQGEPTSRPKAV---TFSPDL---GPVPHEGLGEYNRA-VSKLSAALSSL 740
+PG E +P P T PD G VP Y++ S + +L S
Sbjct: 724 LPGPENHRAGSNEDPILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEASDVEISLESD 783
Query: 741 QRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPG 800
D + + L PP G+ PPP A PT P A+ P PA+ P + PG
Sbjct: 784 SDDSVVIVPEGLPPLPPPPPSGATPPPIA-----PTGPPTASPPVPAKEEPEELPA-APG 837
Query: 801 PSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP 860
P P P P + L P P VP E TP
Sbjct: 838 PLPPPPPPPPPVPGPVTLPP---------------------PQLVP----------EGTP 866
Query: 861 PE--EPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKD 918
PA L I + S + E+E + E+ EE+ E E Y +
Sbjct: 867 GGGGPPALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEE----YFE 922
Query: 919 EDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRRE--EAARLAQEEAPGPAPL 976
E++ E+E ++ E + EE ++ +E+E+ + E A +E AP P L
Sbjct: 923 EEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTL 982
Query: 977 VSAVPMATPAPAARAPAEEEVG 998
A+P P + E E G
Sbjct: 983 PPALPPPESPPKVQPEPEPEPG 1004
Score = 43.1 bits (100), Expect = 0.002
Identities = 100/433 (23%), Positives = 149/433 (34%), Gaps = 66/433 (15%)
Query: 383 FRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAWNRQLSRPLS-QAVSFSTPFGLD 441
FR P GP P GS S PS M + G + + P + + S P GL
Sbjct: 660 FRAPPFHPPGPM-PSVGSMPSAGPMPSAGPMPSAGPVPSARPGPPTTANHLGLSVP-GLV 717
Query: 442 SDVDVVMGDPVLLRSVSSDSLGPPRPAPARTP--TQPPPEP--GDLPTI-------EEAL 490
S ++ P R+ S++ P AP+ TP T PP E G +P EEA
Sbjct: 718 SVPPRLLPGPENHRAGSNED---PILAPSGTPPPTIPPDETFGGRVPRPAFVHYDKEEAS 774
Query: 491 QIIHSAEPR------LLPDGAAD-----GSFYLHSPEGPSKPSLASPYLPEGTSKPLSDR 539
+ S E ++P+G S P P+ P ASP +P +K +
Sbjct: 775 DVEISLESDSDDSVVIVPEGLPPLPPPPPSGATPPPIAPTGPPTASPPVP---AKEEPEE 831
Query: 540 PTKAPVYMPHPETPSKPSPCLVGEASKPP-------APSEGSPKAVASSPAATNSEVKMT 592
AP +P P P P P G + PP P G P A+ N +
Sbjct: 832 LPAAPGPLPPPPPPPPPVP---GPVTLPPPQLVPEGTPGGGGPPALEEDLTVIN----IN 884
Query: 593 SFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIF 652
S E +++ + E E E E + E++ E ++ E
Sbjct: 885 SSDEEEEEEEEEEEEE------------EEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFE 932
Query: 653 AKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVT-- 710
+ + G+ L+ + E E E E EE + EG P + P A+
Sbjct: 933 EEFEEEEGE---LEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPALPPP 989
Query: 711 -FSPDLGPVPHEGLG---EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPP 766
P + P P G E ++ + Q + E+P + PP
Sbjct: 990 ESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQGEVEREGESPAAGPP 1049
Query: 767 PAAWVIPGPTTGP 779
P V P+ P
Sbjct: 1050 PQELVEEEPSAPP 1062
Score = 34.3 bits (77), Expect = 0.78
Identities = 43/163 (26%), Positives = 65/163 (39%), Gaps = 36/163 (22%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
PP +P + +P PEPG L +E EP + AD + P+L
Sbjct: 987 PPPESPPKVQPEPEPEPGLLLEVE---------EPGTEEERGAD-----------TAPTL 1026
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHP-----ETPSKPSPCLVGEASKPPAPSEGSPKAV 578
A LP S+ +R ++P P P E PS P P L+ E ++ +GS K
Sbjct: 1027 APEALP---SQGEVEREGESPAAGPPPQELVEEEPSAP-PTLLEEETE-----DGSDK-- 1075
Query: 579 ASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPE 621
P T +E +M + E + K + + A PP+
Sbjct: 1076 VQPPPETPAEEEMETETEAEALQEKEQDDTAAMLADFIDCPPD 1118
Score = 33.9 bits (76), Expect = 1.0
Identities = 30/105 (28%), Positives = 40/105 (38%), Gaps = 22/105 (20%)
Query: 540 PTKAPVYMPHPETPSK------PSPCLVGEASKPPAPSE-GSPKAVASSPAATNSEVKMT 592
P P +P PE+P K P P L+ E +P E G+ A +P A S+
Sbjct: 979 PPTLPPALPPPESPPKVQPEPEPEPGLLLEVEEPGTEEERGADTAPTLAPEALPSQ---- 1034
Query: 593 SFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEK 637
E E SP + P P E + E S LEE+
Sbjct: 1035 -----------GEVEREGESPAAGPPPQELVEEEPSAPPTLLEEE 1068
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 62.4 bits (150), Expect = 3e-09
Identities = 160/713 (22%), Positives = 235/713 (32%), Gaps = 173/713 (24%)
Query: 366 EASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEAL-------GK 418
E SP + S V R P GP +PL G+ + H AL G
Sbjct: 271 EVSPEERPSSGQQDVAPDRGP---EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGV 327
Query: 419 AWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGPPRPAP--ARTPTQP 476
SRP +TP + + P L S GPP P P + +
Sbjct: 328 PGEDPSSRP-------ATPELAEPE-----SAPTLRVEPPSPPEGPPNPGPDGGKQDGEA 375
Query: 477 PPEPGDLPTIEEALQIIHSAE------PRLLPDG-----AADGSFYLHSPEGPSKPSLAS 525
PP P ++A +++ + E P +P+G D + +P P +
Sbjct: 376 PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
Query: 526 PYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSP---------CLVGEASKPPAPSEGSPK 576
P E T L D P P PE ++ P + E S PAPS +PK
Sbjct: 436 PKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPK 495
Query: 577 AVASSPAATNSEVKMTSFAERKKQLVKAEA---EAGAGSPTSTPAPPEALSSEMSELSAR 633
+ A SE S L AE+ E G GS + A PE +E +E
Sbjct: 496 SCLKHRPAAASEGPAAS-----PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPA 550
Query: 634 LEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGER 693
E+ A +R+ E A+ R G + + P PG R
Sbjct: 551 GAERA----APERKAERGGAELR-----------------GAKKFSVSSCRARPRPGVSR 589
Query: 694 PAGEGQGE-PTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQ 752
P G P +R GPV + AAL LQ
Sbjct: 590 PLERASGRLPLARS---------GPV------------WRSEAALDDLQ----------- 617
Query: 753 RLLAPPEAPGSAPPPAAWVIPGPT-TGPKAASPSPARR-------VPATRRSPGPGPSQS 804
PE + P P GP +G +AASP+ R+ P TR +
Sbjct: 618 ---GLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPA 674
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEE------ 858
P ++ P +LR L+ + ++++S ++V ++ ++L EE
Sbjct: 675 PSEDRNPFPVKLRSTSLSLKYRDGAS-QEVKGVKRYS-AEVRLERSLTVLPKEEKCPLGT 732
Query: 859 ------------------TPPEEPAARPGLIEIPLGSL----ADPAAEDEGDGSPAGAED 896
PPE +++P L PL PA D G G
Sbjct: 733 APALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPG------- 785
Query: 897 SLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKE 956
E EPR E +P A+K SL + + W V ++
Sbjct: 786 ----EREPRKEPRTA-------EKRPLRRGAEK--SLPPAATGPGADGQPAPPWITVTRQ 832
Query: 957 QRREEAARLA-QEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQE 1008
+RR + QE+ PG L S P A+ P + ++ DF R +
Sbjct: 833 KRRGTLDQPPNQEDKPGARTLKS-----EPGKQAKVPERGQEPVKQADFVRSK 880
Score = 59.3 bits (142), Expect = 2e-08
Identities = 138/562 (24%), Positives = 187/562 (33%), Gaps = 74/562 (13%)
Query: 476 PPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH--SPEGPSKPSLASP-YLPEGT 532
PPP PG LP + S+E LP + S LH P K S+ SP ++ + T
Sbjct: 136 PPPPPGGLPA-KRGEDAGMSSEDDGLPRSPPEMSL-LHDVGPGTTIKVSVVSPDHVSDST 193
Query: 533 SKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASK-----PPAPSEGSPKAVASSPAATNS 587
+ APV P++ S CL A+K P S SS A + S
Sbjct: 194 VSARISDNSLAPV--ADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSES 251
Query: 588 EVKMTSFAERKKQLVKAEAEAGAGSPTST------------PAPPEALSSEMSELSARLE 635
+T E ++ K E S+ P PP L
Sbjct: 252 LSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPP--------- 302
Query: 636 EKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPRE--ASGEAEAEAEEADSGPVPGGER 693
A++ R++ H L S P E +S A E E +S P E
Sbjct: 303 ---GGARARRARLQ-----HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVE- 353
Query: 694 PAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL-TDQQQ 752
P +G P P + P G A K + + + T +
Sbjct: 354 PPSPPEGPPNPGPDGGKQDGEAPPA-----GPCAPATDKAEEVVCAPEDVASPFPTAIPE 408
Query: 753 RLLAPPEAPGSAPPPAAWVIPGPTTG-PKAASPSPARRVPATRRSPGPGP------SQSP 805
PPE +A A GP PK A P+P + PGP P P
Sbjct: 409 GDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEP 468
Query: 806 RSPKHTRPAELRLAPLTR-VLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
T P + P T +PP L H R + S+ P S L A E+PP EP
Sbjct: 469 ERGAGTEPERIGTEPSTAPAPSPPAPKSCLKH-RPAAASEGP--AASPPLAAAESPPVEP 525
Query: 865 AARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRV-GLGFFYKDEDKPE 923
PG ++ + P AE + PAGAE + E + G + G F +
Sbjct: 526 G--PGSLDAEAAAPERPKAE-RAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRAR 582
Query: 924 DEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPM- 982
R LER R AR W+ E + Q PGP L P
Sbjct: 583 PRPGVSRP--LERASGRLPLARSGPVWRS-EAALDDLQGLPEPQHAKPGPRKLAERGPQD 639
Query: 983 -----ATPAPAARAPAEEEVGP 999
A+PA ++P E P
Sbjct: 640 SGDRAASPAGPRKSPQEAAAAP 661
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 62.0 bits (149), Expect = 4e-09
Identities = 133/574 (23%), Positives = 187/574 (32%), Gaps = 101/574 (17%)
Query: 357 GHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSP-------- 408
G A P + P ++G+SS R P G P + ++ SSP
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 409 -----------SMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLR-- 455
S A GKA LS T S P + R
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT-----SGPTPGTPSPAMARRS 180
Query: 456 SVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHS-AEPRLLPDGAADGSFYLHS 514
+ +G PRPAP+ P PP G ++ A + HS EP L
Sbjct: 181 RAAGTEVGLPRPAPSARPR--PPTEGPRKSVSSASE--HSTTEPSPAARRRPSAGGGLQR 236
Query: 515 PEGPSKPSLASPYLPEGTSKPLSDRPTKAPVY--MPHPETPSKPSPCLVGEASKPPAPSE 572
P S S A+P S P + +AP + P P+ P V K AP+
Sbjct: 237 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 296
Query: 573 G----SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMS 628
G SP A S AA S+ T A + + +P+ P +L + S
Sbjct: 297 GPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPS 356
Query: 629 ELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPV 688
+ + ++ + + A H +FL P +A A + P
Sbjct: 357 PPATPPSQATTSLGS-----PTLQATH-------SFLPSPPLSPLATPPPQAPPALALP- 403
Query: 689 PGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNR-AVSKLSAALSSLQRDMQRL 747
P P + SP L P+ N AV L A S
Sbjct: 404 -------------PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS--------- 441
Query: 748 TDQQQRLLAPPEAPGSAP--PPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSP 805
PP P AP PPA+ + T P A PS A P + P P P+ P
Sbjct: 442 --------PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA--APPLQVPPSP-PASPP 490
Query: 806 RSPKHTRPAE----LRLAPLTRVLTPPH--------DVDSLPHLRKFSPSQVPVQTRSSI 853
SP T P + L PL PP + +LP P Q P +S+
Sbjct: 491 MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 550
Query: 854 LLAE-ETPPEE--PAARPGLIEIPLGSLADPAAE 884
++ TPP + P L+++P A P +
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Score = 54.3 bits (129), Expect = 7e-07
Identities = 180/814 (22%), Positives = 248/814 (30%), Gaps = 171/814 (21%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P AP +PP P P + A + A + A+ + + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 524 ASPYLPEGTSK-------PLSDRPTKAPVYMPHPETPSKPSPCLV-GEASKPPAPSEGSP 575
A P GTS P S R +AP P + P P G AS P
Sbjct: 77 AGPTRSAGTSSRNPASRPPASGRGERAP-----PAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 576 KAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARL- 634
K + S T + K T +R A + +P TP+P A S + L
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLP 190
Query: 635 ------------EEKRRAIEAQKRR--IEAIFAKHRQRLGKSAFLQVQPREASGEAEAEA 680
E R+++ + E A R+ + R S A +
Sbjct: 191 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 681 EEADSGPVPGG--ERPAGEGQGEPTS----RPKAVT-----FSPDLGPVPHEGLGEYNRA 729
A SGP G PA Q +P RP VT +P LGP+ L A
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-----A 305
Query: 730 VSKLSAALSSLQRDMQRLTDQQQRL---------LAPPE-----------APGSAPPPAA 769
SAAL S T L LAPP +P + PP A
Sbjct: 306 TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA 365
Query: 770 WV-------------IPGPTTGPKAASP---SPARRVPATRRSPGPGPS----------- 802
+P P P A P PA +P + P P S
Sbjct: 366 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 425
Query: 803 -----------QSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRS 851
Q+P SP + P + AP + +PP + P PSQ P +
Sbjct: 426 QAPNALAVHLLQAPFSPPPSPPVQ---APFSPPASPPVSPSATP------PSQAPPSLAA 476
Query: 852 SILLAEETPPEEPAARPGLIEIPLG--SLADP---AAEDEGDGSPAGAEDSLE----EEA 902
L +PP P P P LA P A+ PA A L+ A
Sbjct: 477 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA 536
Query: 903 SSEGE----PRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQR 958
S G+ P L P+ L A + +
Sbjct: 537 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 596
Query: 959 REEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLM 1018
RL APGP P P +R+P+ GP + +L+
Sbjct: 597 SVSGPRLTLALAPGP-----------PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 645
Query: 1019 DDLDKVLRPRAAGSGGPGRGGRRATRP---RSGCCDDSALARSPA-----RGLLGSRL-- 1068
D GP GG A+ P C +A +R PA RG G+ L
Sbjct: 646 D-------------SGP-EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPW 691
Query: 1069 -SKIYSQSTLSLSTVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGSRERDWENGSNASS 1127
S L T+ + P S P+P G + P PG+ G+ A +
Sbjct: 692 PPATGPGSADGLCTIYE-------TEGPESATPAP-GALDPGPSPGTSGGKAAAGAGAGA 743
Query: 1128 PASVPEYTGPRLYKEPSAKSNKFIIHNALSHCCL 1161
+ P+ RL + P ++ + LS L
Sbjct: 744 SSRSPKQA--RLGELPLGALQASVVQHLLSRTLL 775
Score = 52.8 bits (125), Expect = 2e-06
Identities = 132/557 (23%), Positives = 176/557 (31%), Gaps = 130/557 (23%)
Query: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSP--------SMSH 412
S R + PP + G +P P GP S ++G+ + P S
Sbjct: 86 SSRNPASRPPASGRGERAPPAKNTSP-----GPVSSPGRASGTTRPGPLGQKGLRISAEE 140
Query: 413 MEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRS--VSSDSLGPPRPAPA 470
A GKA LS T S P + R + +G PRPAP+
Sbjct: 141 TVARGKATEAPKRSALSAGARRDT-----SGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
Query: 471 RTP-------------------TQPPPEPGDLPTIEEALQ------IIHSAEPRLLPDGA 505
P T+P P P+ LQ + SA P P A
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--A 253
Query: 506 ADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTK--APVYMPHPETP-SKPSPCLVG 562
G +P P+ PS P + P P K AP P +P + PSP
Sbjct: 254 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAAL 313
Query: 563 EASKPPA----------------------PSEGSPKAVAS--SPAATNSEVKMTSFAERK 598
++ PP PS +P ++ + SP AT TS
Sbjct: 314 QSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 373
Query: 599 KQLVKAEAEAGAGSPTSTPAP--PEAL-------------SSEMSELSARLEEKRRAIEA 643
Q + + SP +TP P P AL S +S L+ + A+
Sbjct: 374 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 433
Query: 644 QKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERP--AGEGQGE 701
++A F+ P +A A + S P P A
Sbjct: 434 HL--LQAPFSPPPS----------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV 481
Query: 702 PTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEA- 760
P S P + SP P P A L A Q T Q L +PP +
Sbjct: 482 PPSPPASPPMSPSATPPPQ---APPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538
Query: 761 PGSAP-------PPAAWVIPGPTTGPKAASP----------SPARRVPATRRSPGPGPSQ 803
PG AP P + P P P A+P SP + P RR P PGP
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--RRPPTPGPDT 596
Query: 804 SPRSPKHTRPAELRLAP 820
S P+ T L LAP
Sbjct: 597 SVSGPRLT----LALAP 609
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 62.0 bits (149), Expect = 4e-09
Identities = 132/528 (25%), Positives = 183/528 (34%), Gaps = 104/528 (19%)
Query: 390 SGGPQSPLRGSTGSLKSSPSMSHMEALGKAWNRQ-----LSRPLSQAVSFS-TPFGLDSD 443
S P+ P G S+ S+ S E A R L RP S+++S S TP +
Sbjct: 195 SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA- 253
Query: 444 VDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPD 503
RS S + G PR APA P+QP P+ + A P L P
Sbjct: 254 -----------RSGPS-ARGTPR-APAH-PSQPKPKGLQALRPPQVTPPRKDAAPALGP- 298
Query: 504 GAADGSFYLHSPEGPSKPSLASPYLPEGTSKPL-SDRPTKAPVYMPHPETPSKPS--PCL 560
+ SP G +K P P+ + PL + P P+ P P P PS P L
Sbjct: 299 -LSSSPLATPSPSG-TKARPVPP--PDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354
Query: 561 VGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPP 620
S P P +P ++ + P ++ + L SP S APP
Sbjct: 355 QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT---------SP-SLQAPP 404
Query: 621 EALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEA 680
L+ +S L A ++A +FL + PR+ + +
Sbjct: 405 SPLA--LSSLQATTSLGSPTLQATH-----------------SFLTMSPRQTQASLTSPS 445
Query: 681 EEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLS-----A 735
A + P P P S P + SP + P+ +A+S L+ A
Sbjct: 446 RPASTPP---DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQA 502
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEA---------------PGSAPPPAAWVIPGPTTG-- 778
LSSL M L Q LAPP P APPP TT
Sbjct: 503 PLSSLI--MPPLETQSS--LAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHL 558
Query: 779 --PKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPH 836
P +P P + P+ +P P S +P P L PL + +PP + P
Sbjct: 559 ETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP- 617
Query: 837 LRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAE 884
P Q P L A +PP P PL LA P+ +
Sbjct: 618 -----PPQAPPXLALPPLQAPPSPPASP---------PLSPLATPSPQ 651
Score = 57.4 bits (137), Expect = 9e-08
Identities = 126/493 (25%), Positives = 169/493 (34%), Gaps = 106/493 (21%)
Query: 361 SPRGTEASPPQNNSGS------SSPVFTFRHPL-----LSSGGPQSPLRGSTGSLKSSPS 409
+P ASPP S S SSP+ HPL L+S PQ+PL SS
Sbjct: 459 APLSLPASPPLQTSLSPAVSPLSSPLTI--HPLQALSSLASHSPQAPL--------SSLI 508
Query: 410 MSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLGP---PR 466
M +E L P S +TP L++ + P L++ S+ P
Sbjct: 509 MPPLETQSSLAPPSLQTP---PASLTTP-PLENLPSLA---PPPLQTASAPLTTPHLETP 561
Query: 467 PAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFY---------LHSPEG 517
P PA P Q PP P P E I + P P A L +P
Sbjct: 562 PCPAPCPLQAPPSPLTTPPPETPSSI--ATPPPQAPPALASPPLQGLPSPPLSPLATPPP 619
Query: 518 PSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLV-GEASKPPAPSEGSPK 576
+ P LA P L S P S P +P+ P P+ P+ + L+ S PP+P +P
Sbjct: 620 QAPPXLALPPLQAPPSPPAS--PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677
Query: 577 AVASSP----AATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEALSSEMSEL 630
+ +SP +AT S A Q+ + + SP++TP P P L++ ++
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQV 737
Query: 631 --SARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPR-EASGEAEAEAEEADSGP 687
S R+ + A + LQV P AS A+ P
Sbjct: 738 PPSPPASPPMSPSATPPPRVPPLLA--------APPLQVPPSPPASLPMSPLAKPPPQAP 789
Query: 688 VPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
P P S P FSP S +S L
Sbjct: 790 PALATPPLQALPSPPASFPGQAPFSP------------------SASLPMSPL------- 824
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRS 807
PP+AP P V P P P +P RR P PGP S
Sbjct: 825 ------ATPPPQAPPVLAAPLLQVPPSPPASPTLQAP---------RRPPTPGPDTSVSG 869
Query: 808 PKHTRPAELRLAP 820
P+ T L LAP
Sbjct: 870 PRLT----LALAP 878
Score = 51.2 bits (121), Expect = 6e-06
Identities = 195/887 (21%), Positives = 275/887 (31%), Gaps = 174/887 (19%)
Query: 355 PDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHME 414
P S RGT +P + + R P ++ P+ + G L SSP +
Sbjct: 252 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP--PRKDAAPALGPLSSSPLATPSP 309
Query: 415 ALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPV-----------LLRSVSSDSLG 463
+ KA RP+ + +TP + P+ L+++ S
Sbjct: 310 SGTKA------RPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHS-------AEPRLL-------------PD 503
PP AP T P P L TI +Q+ HS A P L P
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPP-IQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPT 422
Query: 504 GAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMP---------HPETPS 554
A SF SP ++ SL SP P T P P +AP+ +P P
Sbjct: 423 LQATHSFLTMSPR-QTQASLTSPSRPAST--PPDSPPLQAPLSLPASPPLQTSLSPAVSP 479
Query: 555 KPSPCLVGEASKPPAPSEGSPKAVASS----PAATNSEVKMTSFAERKKQLVKAEAE--- 607
SP + + + SP+A SS P T S + S L E
Sbjct: 480 LSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLP 539
Query: 608 -------AGAGSPTSTP-------APPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFA 653
A +P +TP P L + S L+ E +I + A
Sbjct: 540 SLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALA 599
Query: 654 KHRQRLGKSAFL--------QVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSR 705
+ S L Q P A +A S P+ P+ +
Sbjct: 600 SPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 659
Query: 706 PKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAP 765
FSP P SA S L APP +P
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS---------QAPPSLAAPPLQVPPSP 710
Query: 766 PPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVL 825
P + + P T P+A P A P + P P P+ P SP T P R+ PL +
Sbjct: 711 PASPPMSPSATPPPQAPPPLAA---PPLQVPPSP-PASPPMSPSATPPP--RVPPL--LA 762
Query: 826 TPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAED 885
PP V P P+ +P+ + PP P A P L PL +L P A
Sbjct: 763 APPLQVPPSP------PASLPMSPLAK-------PP--PQAPPALATPPLQALPSPPASF 807
Query: 886 EGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEAR 945
G +P SL + P+ P A R +
Sbjct: 808 PGQ-APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT- 865
Query: 946 RRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFT 1005
RL APGP P P +R+P+ GP +
Sbjct: 866 -------------SVSGPRLTLALAPGP-----------PPPPSRSPSSTLSGPDLAGHS 901
Query: 1006 RQEYERRAQLKLMDDLDKVLRPRAAGSGGPGRGGRRATRP---RSGCCDDSALARSPA-- 1060
+L+ D GP GG A+ P C +A +R PA
Sbjct: 902 SSATSTPEELRGYD-------------SGP-EGGAAASPPPDAELAACHPAAWSRGPAPP 947
Query: 1061 ---RGLLGSRL---SKIYSQSTLSLSTVANEAHNNLGVKRPTSRAPSPSGLMSPSRLPGS 1114
RG G+ L S L T+ + P S P+P G + P PG+
Sbjct: 948 LAFRGAPGAPLPWPPATGPGSADGLCTIYE-------TEGPESATPAP-GALDPGPSPGT 999
Query: 1115 RERDWENGSNASSPASVPEYTGPRLYKEPSAKSNKFIIHNALSHCCL 1161
G+ A + + P+ RL + P ++ + LS L
Sbjct: 1000 SGGKAAAGAGAGASSRSPKQA--RLGELPLGALQASVVQHLLSRTLL 1044
Score = 34.7 bits (78), Expect = 0.60
Identities = 65/261 (24%), Positives = 88/261 (33%), Gaps = 50/261 (19%)
Query: 762 GSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR--------SPGPGPSQSP-RSPKHTR 812
G A P + GPT +S +PA R PA+ R + PGP SP R+ TR
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125
Query: 813 P-----------AELRLAPLTRVLTPPHDVDSLPHLRKFS----PSQVPVQTRSSILLAE 857
P AE +A P S R S + P R S
Sbjct: 126 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 185
Query: 858 ET--PPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFF 915
E P P+ARP P S A + E ++ P G G
Sbjct: 186 EVGLPRPAPSARP----------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL- 234
Query: 916 YKDEDKPEDEMAQKRASLLERQQRRAEEAR--RRKQWQEVEKEQRREEAARLAQ------ 967
+P A+ L R AR R + + + +A R Q
Sbjct: 235 ----QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK 290
Query: 968 EEAPGPAPLVSAVPMATPAPA 988
+ AP PL S+ P+ATP+P+
Sbjct: 291 DAAPALGPL-SSSPLATPSPS 310
Score = 32.7 bits (73), Expect = 2.3
Identities = 66/258 (25%), Positives = 84/258 (32%), Gaps = 76/258 (29%)
Query: 684 DSGPVPGGERPAGEGQGEPTSRPKA--------VTFSPDLGPVPHEG----------LGE 725
+S P G R AG P SRP A + GPV G LG+
Sbjct: 72 ESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 131
Query: 726 YNRAVS--------------KLSAALSSLQRDMQRLTD-------QQQRLLAPPEAPGSA 764
+S K SA + +RD T ++ A E
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 191
Query: 765 PPPAAWVIPGPTTGPK-----AASPSPARRVPATRRSP---------------------- 797
P P+A P PT GP+ A+ S PA RR P
Sbjct: 192 PAPSARPRP-PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 798 -----GPGPSQSPRSPKH-TRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRS 851
GP +PR+P H ++P L L P D+ P L S S P+ T S
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS--PLATPS 308
Query: 852 -SILLAEETPPEEPAARP 868
S A PP + AA P
Sbjct: 309 PSGTKARPVPPPDNAATP 326
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 60.8 bits (146), Expect = 8e-09
Identities = 129/511 (25%), Positives = 178/511 (34%), Gaps = 97/511 (18%)
Query: 509 SFYLHSPEGPSKPSLASPYLPEGTSKPLSD------RPTKAPVYMPHPET-PSKPSPCLV 561
SF + +GP P L L E + P+ + A + P E P+K P LV
Sbjct: 217 SFTQETKKGP--PVLLEDELREEVTVPVVQEGSAVKKVASAEIEPPSTEKFPAKIQPPLV 274
Query: 562 GEASKP--PAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSP-TSTPA 618
EA+ P P+E + V S T T+ AE VK + +P PA
Sbjct: 275 EEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENS---VKVQPPPAEEAPLVEFPA 331
Query: 619 ---PPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGE 675
PP A S EL A ++ P A E
Sbjct: 332 EIQPPSAEESPSVELLA---------------------------------EILPPSAE-E 357
Query: 676 AEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSA 735
+ +E A+ P P + P+ E GE S P A ++ P+P EG
Sbjct: 358 SPSEEPPAEILPPPAEKSPSVELLGEIRS-PSAQKAPIEVQPLPAEG------------- 403
Query: 736 ALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRR 795
AL ++ T ++ P P AP A + T A +PA P +
Sbjct: 404 ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLST-----AMETPAEEAPTEFQ 458
Query: 796 SPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSL----PHLRKFSPSQVPVQTRS 851
SP P + + + AE++L T PP D P + S + + +S
Sbjct: 459 SPLPKETTAEEAS-----AEIQLLAATE---PPADETPAEARSPLSEETSAEEAHAEVQS 510
Query: 852 SILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVG 911
LAEET EE +A L+ A E D +PA A+ L EE S+E P
Sbjct: 511 P--LAEETTAEEASAEIQLLA---------AIEAPADETPAEAQSPLSEETSAEEAPAEV 559
Query: 912 LGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAP 971
K E + + S E A A + E E+ E EEAP
Sbjct: 560 QSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAP 619
Query: 972 G---PAPLVSAVPMATPAPAARAPAEEEVGP 999
P P A P PA APAE + P
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPP 650
Score = 59.3 bits (142), Expect = 2e-08
Identities = 123/541 (22%), Positives = 190/541 (35%), Gaps = 111/541 (20%)
Query: 465 PRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFY-----LHSPEGPS 519
PRPA T Q P + P E A + ++ ++ P A + + P
Sbjct: 283 PRPAE-ETHVQVQPSTEETPDAEAATAVAENSV-KVQPPPAEEAPLVEFPAEIQPPSAEE 340
Query: 520 KPS--LASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKP---------- 567
PS L + LP + S+ P P + P PS L+GE P
Sbjct: 341 SPSVELLAEILPPSAEESPSEEP---PAEILPPPAEKSPSVELLGEIRSPSAQKAPIEVQ 397
Query: 568 PAPSEGSPKAVASSPAATNSEVKMTSFAE--------------RKKQLVKAEAEAGAGSP 613
P P+EG A+ +PA + A+ R+ QL A +P
Sbjct: 398 PLPAEG---ALEEAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAMETPAEEAP 454
Query: 614 TS--TPAPPEALSSEMS------------------ELSARLEEKRRAIEAQKRRIEAIFA 653
T +P P E + E S E + L E+ A EA +++ A
Sbjct: 455 TEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSAEEAHAE-VQSPLA 513
Query: 654 KHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSP 713
+ SA +Q+ A+ EA A+ A++ E A E E S P A S
Sbjct: 514 EETTAEEASAEIQLL---AAIEAPADETPAEAQSPLSEETSAEEAPAEVQS-PSAKGVSI 569
Query: 714 DLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPP--EAPGSAPPPAAWV 771
+ P+ + + SAA+ L + + PP EAP PP A
Sbjct: 570 EEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEE 629
Query: 772 IPGPTTGPKA------ASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVL 825
P P A P PA PA + P P PAE++ P
Sbjct: 630 APAEVQPPPAEEAPAEVQPPPAEEAPAEVQPP----------PAEEAPAEVQPPPAEEA- 678
Query: 826 TPPHDVDSLPHLRKFSPSQVPVQTRSSIL---LAEETPPEE--------PAARPGLIEIP 874
P +V SLP + P++ + + A++ P EE PA E P
Sbjct: 679 --PAEVQSLP------AEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFP 730
Query: 875 LGSLADPAAEDEGDGSPAGAEDSLEEEASSE-------GEPRVGLGFFYKDEDKPEDEMA 927
+G + + + +P +++L E S+E G P V LG + + +E++
Sbjct: 731 IGEASAEVSPPPSEQTP--EDEALVENVSTEFQSPQVAGIPAVKLGSVVLEGEAKFEEVS 788
Query: 928 Q 928
+
Sbjct: 789 K 789
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 60.5 bits (145), Expect = 1e-08
Identities = 98/421 (23%), Positives = 141/421 (33%), Gaps = 43/421 (10%)
Query: 456 SVSSDSLGPPRPAPARTPTQP--PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH 513
++ S P PAP T + P P EP T E A P + A +
Sbjct: 236 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KS 293
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
+P P +P+ +P P T+ P PT P P TP +P+P A P P E
Sbjct: 294 APTTPKEPAPTTPKKPAPTT-PKEPAPTTPKE--PTPTTPKEPAPTTKEPA--PTTPKEP 348
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS--TPAPPEALSSEMSELS 631
+P A T E T+ E K SPT+ PAP S+ +
Sbjct: 349 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKE 402
Query: 632 ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-G 690
+ A K + K + A + A P P
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462
Query: 691 GERPAGEGQGEP---TSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
++PA EP T + A T L P E L+ +
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE--------------KLAPTTPEKPAP 508
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP-SPARRVPATRRSPGPGPSQ--S 804
T ++ PE P P P PTT PKAA+P +P P T + P P + +
Sbjct: 509 TTPEELAPTTPEEPTPTTPEE----PAPTT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPA 563
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P +PK T P + T + P P ++ +P+ T ++ T P+
Sbjct: 564 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 623
Query: 865 A 865
A
Sbjct: 624 A 624
Score = 54.7 bits (130), Expect = 6e-07
Identities = 79/359 (22%), Positives = 120/359 (33%), Gaps = 34/359 (9%)
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAV 578
+KP+ + +G + PT P TP +P+P + A P P E +P
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTT 252
Query: 579 ASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKR 638
S+P T+ K+ + A + T PAP + SA K
Sbjct: 253 KSAPTTPKEPAPTTT-----KEPAPTTPKEPAPTTTKEPAPT-------TTKSAPTTPKE 300
Query: 639 RAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGG-ERPAGE 697
A K+ + K P+E + + A P P ++PA
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 359
Query: 698 GQGEP---TSRPKAVTFSPDLGPV-PHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQR 753
EP T + A T + + P P E ++ + + T ++
Sbjct: 360 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-- 417
Query: 754 LLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQ-----SPRSP 808
P P P P PTT K A +P P T + P P ++ +P+ P
Sbjct: 418 ---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 474
Query: 809 KHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP--PEEPA 865
T P E AP T P + L P+ + + E TP PEEPA
Sbjct: 475 APTTPKE--TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 531
Score = 44.3 bits (103), Expect = 8e-04
Identities = 82/407 (20%), Positives = 127/407 (31%), Gaps = 35/407 (8%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P PAP T + P PT ++ A + +P P KP+
Sbjct: 385 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 444
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPA 583
+P P T+ P PT P P TP +P+P E + P P + +P
Sbjct: 445 TTPKEPAPTT-PKEPAPTTTK--KPAPTTPKEPAPTTPKETA-PTTPKKLTPTTPEKLAP 500
Query: 584 ATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEALSSEMSELSARLEEKRRAI 641
T + T+ ++L E + PAP P+A + + A K A
Sbjct: 501 TTPEKPAPTT----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-GGERPAGEGQG 700
K + + P G A +E P P ++PA +
Sbjct: 557 TTPKEP------------APTTPKETAPTTPKGTAPTTLKE----PAPTTPKKPAPKELA 600
Query: 701 EPTSRPKAVTFSPDLGPVPHEGLG---EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAP 757
T++ T P +G A + + + T ++ P
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660
Query: 758 PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELR 817
+ P P TT K A +P P T + P P +P+ P T P
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPE--T 715
Query: 818 LAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P T ++ P + K P + A E P+EP
Sbjct: 716 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 762
Score = 37.7 bits (86), Expect = 0.071
Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 16/188 (8%)
Query: 464 PPRPAPARTPTQPPPEP--GDLPTI--EEALQIIHSAEPRLLPDGAADGSFYLHSPE-GP 518
P PAP TP +P P G PT E A P+ L G S + P
Sbjct: 628 PKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEA---------SKPPA 569
+ P +P P+ + +P P P T +P E S P
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Query: 570 PSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSE 629
+E +PKA+ +SP T A + + A+ + +TP A + +M++
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA-APKMTK 805
Query: 630 LSARLEEK 637
+A EK
Sbjct: 806 ETATTTEK 813
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 60.5 bits (145), Expect = 1e-08
Identities = 98/421 (23%), Positives = 141/421 (33%), Gaps = 43/421 (10%)
Query: 456 SVSSDSLGPPRPAPARTPTQP--PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH 513
++ S P PAP T + P P EP T E A P + A +
Sbjct: 277 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KS 334
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
+P P +P+ +P P T+ P PT P P TP +P+P A P P E
Sbjct: 335 APTTPKEPAPTTPKKPAPTT-PKEPAPTTPKE--PTPTTPKEPAPTTKEPA--PTTPKEP 389
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS--TPAPPEALSSEMSELS 631
+P A T E T+ E K SPT+ PAP S+ +
Sbjct: 390 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKE 443
Query: 632 ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-G 690
+ A K + K + A + A P P
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503
Query: 691 GERPAGEGQGEP---TSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
++PA EP T + A T L P E L+ +
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE--------------KLAPTTPEKPAP 549
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP-SPARRVPATRRSPGPGPSQ--S 804
T ++ PE P P P PTT PKAA+P +P P T + P P + +
Sbjct: 550 TTPEELAPTTPEEPTPTTPEE----PAPTT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPA 604
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P +PK T P + T + P P ++ +P+ T ++ T P+
Sbjct: 605 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 664
Query: 865 A 865
A
Sbjct: 665 A 665
Score = 54.7 bits (130), Expect = 6e-07
Identities = 79/359 (22%), Positives = 120/359 (33%), Gaps = 34/359 (9%)
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAV 578
+KP+ + +G + PT P TP +P+P + A P P E +P
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTT 293
Query: 579 ASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKR 638
S+P T+ K+ + A + T PAP + SA K
Sbjct: 294 KSAPTTPKEPAPTTT-----KEPAPTTPKEPAPTTTKEPAPT-------TTKSAPTTPKE 341
Query: 639 RAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGG-ERPAGE 697
A K+ + K P+E + + A P P ++PA
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 400
Query: 698 GQGEP---TSRPKAVTFSPDLGPV-PHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQR 753
EP T + A T + + P P E ++ + + T ++
Sbjct: 401 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-- 458
Query: 754 LLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQ-----SPRSP 808
P P P P PTT K A +P P T + P P ++ +P+ P
Sbjct: 459 ---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 515
Query: 809 KHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP--PEEPA 865
T P E AP T P + L P+ + + E TP PEEPA
Sbjct: 516 APTTPKE--TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 572
Score = 44.3 bits (103), Expect = 8e-04
Identities = 82/407 (20%), Positives = 127/407 (31%), Gaps = 35/407 (8%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P PAP T + P PT ++ A + +P P KP+
Sbjct: 426 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 485
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPA 583
+P P T+ P PT P P TP +P+P E + P P + +P
Sbjct: 486 TTPKEPAPTT-PKEPAPTTTK--KPAPTTPKEPAPTTPKETA-PTTPKKLTPTTPEKLAP 541
Query: 584 ATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEALSSEMSELSARLEEKRRAI 641
T + T+ ++L E + PAP P+A + + A K A
Sbjct: 542 TTPEKPAPTT----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-GGERPAGEGQG 700
K + + P G A +E P P ++PA +
Sbjct: 598 TTPKEP------------APTTPKETAPTTPKGTAPTTLKE----PAPTTPKKPAPKELA 641
Query: 701 EPTSRPKAVTFSPDLGPVPHEGLG---EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAP 757
T++ T P +G A + + + T ++ P
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701
Query: 758 PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELR 817
+ P P TT K A +P P T + P P +P+ P T P
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPE--T 756
Query: 818 LAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P T ++ P + K P + A E P+EP
Sbjct: 757 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 803
Score = 37.7 bits (86), Expect = 0.071
Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 16/188 (8%)
Query: 464 PPRPAPARTPTQPPPEP--GDLPTI--EEALQIIHSAEPRLLPDGAADGSFYLHSPE-GP 518
P PAP TP +P P G PT E A P+ L G S + P
Sbjct: 669 PKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 727
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEA---------SKPPA 569
+ P +P P+ + +P P P T +P E S P
Sbjct: 728 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Query: 570 PSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSE 629
+E +PKA+ +SP T A + + A+ + +TP A + +M++
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA-APKMTK 846
Query: 630 LSARLEEK 637
+A EK
Sbjct: 847 ETATTTEK 854
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 60.5 bits (145), Expect = 1e-08
Identities = 98/421 (23%), Positives = 141/421 (33%), Gaps = 43/421 (10%)
Query: 456 SVSSDSLGPPRPAPARTPTQP--PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH 513
++ S P PAP T + P P EP T E A P + A +
Sbjct: 329 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KS 386
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
+P P +P+ +P P T+ P PT P P TP +P+P A P P E
Sbjct: 387 APTTPKEPAPTTPKKPAPTT-PKEPAPTTPKE--PTPTTPKEPAPTTKEPA--PTTPKEP 441
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS--TPAPPEALSSEMSELS 631
+P A T E T+ E K SPT+ PAP S+ +
Sbjct: 442 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKE 495
Query: 632 ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-G 690
+ A K + K + A + A P P
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555
Query: 691 GERPAGEGQGEP---TSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
++PA EP T + A T L P E L+ +
Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE--------------KLAPTTPEKPAP 601
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP-SPARRVPATRRSPGPGPSQ--S 804
T ++ PE P P P PTT PKAA+P +P P T + P P + +
Sbjct: 602 TTPEELAPTTPEEPTPTTPEE----PAPTT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPA 656
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P +PK T P + T + P P ++ +P+ T ++ T P+
Sbjct: 657 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 716
Query: 865 A 865
A
Sbjct: 717 A 717
Score = 54.7 bits (130), Expect = 6e-07
Identities = 79/359 (22%), Positives = 120/359 (33%), Gaps = 34/359 (9%)
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAV 578
+KP+ + +G + PT P TP +P+P + A P P E +P
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTT 345
Query: 579 ASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKR 638
S+P T+ K+ + A + T PAP + SA K
Sbjct: 346 KSAPTTPKEPAPTTT-----KEPAPTTPKEPAPTTTKEPAPT-------TTKSAPTTPKE 393
Query: 639 RAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGG-ERPAGE 697
A K+ + K P+E + + A P P ++PA
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 452
Query: 698 GQGEP---TSRPKAVTFSPDLGPV-PHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQR 753
EP T + A T + + P P E ++ + + T ++
Sbjct: 453 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-- 510
Query: 754 LLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQ-----SPRSP 808
P P P P PTT K A +P P T + P P ++ +P+ P
Sbjct: 511 ---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 567
Query: 809 KHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP--PEEPA 865
T P E AP T P + L P+ + + E TP PEEPA
Sbjct: 568 APTTPKE--TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 624
Score = 44.3 bits (103), Expect = 8e-04
Identities = 82/407 (20%), Positives = 127/407 (31%), Gaps = 35/407 (8%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P PAP T + P PT ++ A + +P P KP+
Sbjct: 478 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 537
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPA 583
+P P T+ P PT P P TP +P+P E + P P + +P
Sbjct: 538 TTPKEPAPTT-PKEPAPTTTK--KPAPTTPKEPAPTTPKETA-PTTPKKLTPTTPEKLAP 593
Query: 584 ATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEALSSEMSELSARLEEKRRAI 641
T + T+ ++L E + PAP P+A + + A K A
Sbjct: 594 TTPEKPAPTT----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-GGERPAGEGQG 700
K + + P G A +E P P ++PA +
Sbjct: 650 TTPKEP------------APTTPKETAPTTPKGTAPTTLKE----PAPTTPKKPAPKELA 693
Query: 701 EPTSRPKAVTFSPDLGPVPHEGLG---EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAP 757
T++ T P +G A + + + T ++ P
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753
Query: 758 PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELR 817
+ P P TT K A +P P T + P P +P+ P T P
Sbjct: 754 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPE--T 808
Query: 818 LAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P T ++ P + K P + A E P+EP
Sbjct: 809 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 855
Score = 37.7 bits (86), Expect = 0.071
Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 16/188 (8%)
Query: 464 PPRPAPARTPTQPPPEP--GDLPTI--EEALQIIHSAEPRLLPDGAADGSFYLHSPE-GP 518
P PAP TP +P P G PT E A P+ L G S + P
Sbjct: 721 PKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 779
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEA---------SKPPA 569
+ P +P P+ + +P P P T +P E S P
Sbjct: 780 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 570 PSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSE 629
+E +PKA+ +SP T A + + A+ + +TP A + +M++
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA-APKMTK 898
Query: 630 LSARLEEK 637
+A EK
Sbjct: 899 ETATTTEK 906
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 60.5 bits (145), Expect = 1e-08
Identities = 98/421 (23%), Positives = 141/421 (33%), Gaps = 43/421 (10%)
Query: 456 SVSSDSLGPPRPAPARTPTQP--PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH 513
++ S P PAP T + P P EP T E A P + A +
Sbjct: 370 TIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KS 427
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
+P P +P+ +P P T+ P PT P P TP +P+P A P P E
Sbjct: 428 APTTPKEPAPTTPKKPAPTT-PKEPAPTTPKE--PTPTTPKEPAPTTKEPA--PTTPKEP 482
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTS--TPAPPEALSSEMSELS 631
+P A T E T+ E K SPT+ PAP S+ +
Sbjct: 483 APTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP------SPTTPKEPAPTTTKSAPTTTKE 536
Query: 632 ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-G 690
+ A K + K + A + A P P
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596
Query: 691 GERPAGEGQGEP---TSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRL 747
++PA EP T + A T L P E L+ +
Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE--------------KLAPTTPEKPAP 642
Query: 748 TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP-SPARRVPATRRSPGPGPSQ--S 804
T ++ PE P P P PTT PKAA+P +P P T + P P + +
Sbjct: 643 TTPEELAPTTPEEPTPTTPEE----PAPTT-PKAAAPNTPKEPAPTTPKEPAPTTPKEPA 697
Query: 805 PRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P +PK T P + T + P P ++ +P+ T ++ T P+
Sbjct: 698 PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGT 757
Query: 865 A 865
A
Sbjct: 758 A 758
Score = 54.7 bits (130), Expect = 6e-07
Identities = 79/359 (22%), Positives = 120/359 (33%), Gaps = 34/359 (9%)
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAV 578
+KP+ + +G + PT P TP +P+P + A P P E +P
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA--PTTPKEPAPTTT 386
Query: 579 ASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKR 638
S+P T+ K+ + A + T PAP + SA K
Sbjct: 387 KSAPTTPKEPAPTTT-----KEPAPTTPKEPAPTTTKEPAPT-------TTKSAPTTPKE 434
Query: 639 RAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGG-ERPAGE 697
A K+ + K P+E + + A P P ++PA
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEP-TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT 493
Query: 698 GQGEP---TSRPKAVTFSPDLGPV-PHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQR 753
EP T + A T + + P P E ++ + + T ++
Sbjct: 494 TPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE-- 551
Query: 754 LLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQ-----SPRSP 808
P P P P PTT K A +P P T + P P ++ +P+ P
Sbjct: 552 ---PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEP 608
Query: 809 KHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP--PEEPA 865
T P E AP T P + L P+ + + E TP PEEPA
Sbjct: 609 APTTPKE--TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPA 665
Score = 44.3 bits (103), Expect = 8e-04
Identities = 82/407 (20%), Positives = 127/407 (31%), Gaps = 35/407 (8%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P PAP T + P PT ++ A + +P P KP+
Sbjct: 519 PKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP 578
Query: 524 ASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPA 583
+P P T+ P PT P P TP +P+P E + P P + +P
Sbjct: 579 TTPKEPAPTT-PKEPAPTTTK--KPAPTTPKEPAPTTPKETA-PTTPKKLTPTTPEKLAP 634
Query: 584 ATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEALSSEMSELSARLEEKRRAI 641
T + T+ ++L E + PAP P+A + + A K A
Sbjct: 635 TTPEKPAPTT----PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVP-GGERPAGEGQG 700
K + + P G A +E P P ++PA +
Sbjct: 691 TTPKEP------------APTTPKETAPTTPKGTAPTTLKE----PAPTTPKKPAPKELA 734
Query: 701 EPTSRPKAVTFSPDLGPVPHEGLG---EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAP 757
T++ T P +G A + + + T ++ P
Sbjct: 735 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 794
Query: 758 PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELR 817
+ P P TT K A +P P T + P P +P+ P T P
Sbjct: 795 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPE--T 849
Query: 818 LAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEP 864
P T ++ P + K P + A E P+EP
Sbjct: 850 PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP 896
Score = 37.7 bits (86), Expect = 0.071
Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 16/188 (8%)
Query: 464 PPRPAPARTPTQPPPEP--GDLPTI--EEALQIIHSAEPRLLPDGAADGSFYLHSPE-GP 518
P PAP TP +P P G PT E A P+ L G S + P
Sbjct: 762 PKEPAPT-TPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 820
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEA---------SKPPA 569
+ P +P P+ + +P P P T +P E S P
Sbjct: 821 TTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 570 PSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSE 629
+E +PKA+ +SP T A + + A+ + +TP A + +M++
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTA-APKMTK 939
Query: 630 LSARLEEK 637
+A EK
Sbjct: 940 ETATTTEK 947
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 60.5 bits (145), Expect = 1e-08
Identities = 141/562 (25%), Positives = 189/562 (33%), Gaps = 101/562 (17%)
Query: 515 PEGPSKPSLASPYL-PEGTSKPLSDRPTKA--PVYMPHPETPSKPSPCLVGEASKPPAPS 571
P P KP L P+ P G P D P + P P PE + ++S + +
Sbjct: 405 PPAP-KPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLA 463
Query: 572 EGSPKAVASSPAATNSEVKMTSFAERKKQL----------VKAEAEAGAGSPTSTPAPPE 621
+ E + + AE+ K+L +KAE A +P STPAPP
Sbjct: 464 VERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP-STPAPPP 522
Query: 622 ALSSEMSELSA-----------RLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPR 670
A+ E+ A EE +A AQ + A G +
Sbjct: 523 AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSST--- 579
Query: 671 EASGEAEAEAEE----ADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEY 726
+SG EA E + GP P E P P PK P P P +GLG Y
Sbjct: 580 -SSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQP-PSQGLG-Y 636
Query: 727 NRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPP------PAAWVIPGPTTGPK 780
+ L Q++ +L QQQ+ GSAPP P V G P+
Sbjct: 637 PKYQKSLPPRFQRQQQE--QLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQ 694
Query: 781 AASPSPARRVPATRRSPGPGPSQS--PR---SPKHTRPAELRLAPLTRVLTP-PHDVDSL 834
A P P P P P P + PR P + P L+ P P H +
Sbjct: 695 APPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLV 754
Query: 835 PHLRKFS--PSQVPVQTRSSILLAEE-TPPEEP------------AARPGLIEIPLGSLA 879
P R S S P + +L E TPP +P A P + PL A
Sbjct: 755 PRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAA 814
Query: 880 DPAAEDEGDGSPAGAEDSLEEEASS------EGEPRVGLGFFYKDEDKP--------EDE 925
D +D+G S +S G P + F +E P DE
Sbjct: 815 D--EDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDE 872
Query: 926 MAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEA-PGPAPLVSAVPMAT 984
+A + Q +KE +EE A+L EA PA V +
Sbjct: 873 VA-------------------KIQTPPPKKEPPKEETAQLTGPEAGRKPARGVGSGGQGP 913
Query: 985 PAPAARAPAEEEVGPRKGDFTR 1006
P P + E GPR G R
Sbjct: 914 PPPRRESRTETRWGPRPGSSRR 935
Score = 52.4 bits (124), Expect = 3e-06
Identities = 170/766 (22%), Positives = 252/766 (32%), Gaps = 143/766 (18%)
Query: 422 RQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSS-DSLGPPRPAPARTPTQPP-PE 479
R L+ PL QA G+ S+ V P L S G P P +R P + P P
Sbjct: 804 RPLTSPLRQAADEDDK-GMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPR 862
Query: 480 PGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSD- 538
P P + + I + P+ P + + L PE KP+ +G P +
Sbjct: 863 PLPWPPGSDEVAKIQTPPPKKEPP--KEETAQLTGPEAGRKPARGVGSGGQGPPPPRRES 920
Query: 539 --------RPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVK 590
RP + +P PE P P P G KPP P++ V P +
Sbjct: 921 RTETRWGPRPGSSRRGIP-PEEPGAP-PRRAGPIKKPPPPTK-----VEELPPKPLEQGD 973
Query: 591 MTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEA 650
T + L + + G T PP S L +R + + R
Sbjct: 974 ETPKPPKPDPLKITKGKLGGPKET----PPNGNLSPAPRLRRDYSYERVGPTSCRGRGRG 1029
Query: 651 -IFAKHRQRLGK--SAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPK 707
FA+ R G + RE E ++ G G P +G S +
Sbjct: 1030 EYFARGRGFRGTYGGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAP-RGRTASETR 1088
Query: 708 AVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPP 767
+ + P G + + S S D + T ++ L P AP PPP
Sbjct: 1089 SEGSEYEEIPKRRRQRGSETGSETHESDLAPS---DKEAPTPKEGTLTQVPLAP---PPP 1142
Query: 768 AAWVIPGPTT----GPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTR 823
A P P G + +P R VP+ RR G G R P P
Sbjct: 1143 GAPPSPAPARFTARGGRVFTP---RGVPS-RRGRGGG-----RPPPQVCPG--------- 1184
Query: 824 VLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAA 883
+PP + +P + P T P P+ P ++ G L+ A
Sbjct: 1185 -WSPP--------AKSLAPKKPP------------TGPLPPSKEPLKEKLIPGPLSPVAR 1223
Query: 884 EDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEE 943
GS G ED E ++R +QQ +
Sbjct: 1224 GGSNGGSNVGMEDG---------------------------ERPRRRRHGRAQQQDKPPR 1256
Query: 944 ARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGD 1003
RR KQ +E + + APGP ++ V +A PAP A ++ + D
Sbjct: 1257 FRRLKQERENAARGSEGKPSLTLPASAPGPEEALTTVTVA-PAPRRAAAKSPDLSNQNSD 1315
Query: 1004 FTRQEYERRAQLKLMDDLDK---------VLRPRAAGSGGPGRGGRRATRPRSGCCDDSA 1054
+E+E ++ + +L P+A G+ G G GG SA
Sbjct: 1316 QANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGG--------AVPGISA 1367
Query: 1055 LARSPARGLLGSRLSKIYSQSTLSLSTVANEAHNNL---GVKRPTSRAPS------PSGL 1105
++R S+ +K S+ + S E N G K +S + S P G
Sbjct: 1368 MSRGDL-----SQRAKDLSKRSFSSQRPGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGR 1422
Query: 1106 MSPSRLPGSRERDWENGSNASSPASVPEYTGPRLYKEPSAKSNKFI 1151
P R +R W + N S P PE P L P S+ +
Sbjct: 1423 TGPGR---GDKRSWPSPKNRSRP---PEERPPGLPLPPPPPSSSAV 1462
Score = 52.0 bits (123), Expect = 4e-06
Identities = 88/389 (22%), Positives = 132/389 (33%), Gaps = 55/389 (14%)
Query: 456 SVSSDSLGPPRPAPARTPTQP--PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLH 513
+V + PP P PA PT P EP P + +A P L+ G + S
Sbjct: 523 AVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSG 582
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
S E ASP P+ SK + P + P P +P +G +PP+ G
Sbjct: 583 SFE-------ASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLG 635
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTST-PAPPEALSSEMSELSA 632
PK S P + + ++++Q + + G+ PT P+PP+ ++
Sbjct: 636 YPKYQKSLPPRFQRQ-QQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVT-------- 686
Query: 633 RLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFL--------------QVQPREASGEAEA 678
A+ A + A + LG+ + V PR G
Sbjct: 687 -----LGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPL 741
Query: 679 EAEEA---DSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHE----GLGEYNRAVS 731
+ SG VP +G EP R A + G P + +G+ A
Sbjct: 742 DFYPPGVHPSGLVPRERSDSGGSSSEPFDR-HAPAMLRERGTPPVDPKLAWVGDVFTATP 800
Query: 732 KLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVP 791
L+S R D+ R PP PPP ++ P A P R P
Sbjct: 801 AEPRPLTSPLRQAADEDDKGMRSETPP-----VPPPPPYLASYPGFPENGAPGPPISRFP 855
Query: 792 ATRRSPGPGPSQSPRSPKHTRPAELRLAP 820
PGP P P A+++ P
Sbjct: 856 LEE----PGPRPLPWPPGSDEVAKIQTPP 880
Score = 43.5 bits (101), Expect = 0.001
Identities = 100/401 (24%), Positives = 140/401 (34%), Gaps = 86/401 (21%)
Query: 514 SPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEG 573
SP+G K + P G S PL+ P + P P E P +P PPAP +G
Sbjct: 1671 SPDGGLKGAAEGPPKRPGGSSPLNAVPCEGP---PGSEPPRRP----------PPAPHDG 1717
Query: 574 SPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSAR 633
K + + + Q E G P+ P PP + + R
Sbjct: 1718 DRKELPREQPLPPGPI-----GTERSQRTDRGTEPGPIRPSHRPGPPVQFGTSDKDSDLR 1772
Query: 634 LEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSG-----PV 688
L +++A+K + A + + S ++ P A+ AE +++ DSG P
Sbjct: 1773 L-VVGDSLKAEKE----LTASVTEAIPVSRDWELLP-SAAASAEPQSKNLDSGHCVPEPS 1826
Query: 689 PGGERPAGE---GQGEPTS------------RPKAVTF---SPDLGPVPHEGLGEYNRAV 730
G+R E G P+S P + F +P L P + L
Sbjct: 1827 SSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRSQPL-YLPPGP 1885
Query: 731 SKLSAALSSLQRDMQRL---TDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPA 787
+ SA LS L Q L T Q L P PPP+ P A PSP
Sbjct: 1886 APPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSP-------AFCPSP- 1937
Query: 788 RRVPATR----RSPGPGPS---QSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKF 840
+P T R P PS +P P AP ++L P D
Sbjct: 1938 --LPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVD---------- 1985
Query: 841 SPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADP 881
SQ+PV S+ PP P A P L +P+G P
Sbjct: 1986 --SQLPVVNFGSL------PPAPPPAPPPLSLLPVGPALQP 2018
Score = 40.4 bits (93), Expect = 0.011
Identities = 72/301 (23%), Positives = 102/301 (33%), Gaps = 54/301 (17%)
Query: 596 ERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKH 655
ER+ +E + P S P P EAL++ +
Sbjct: 1263 ERENAARGSEGKPSLTLPASAPGPEEALTT-----------------------VTVAPAP 1299
Query: 656 RQRLGKSAFLQVQ-PREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPD 714
R+ KS L Q +A+ E E +E +D G++ A P V +P
Sbjct: 1300 RRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEA----------PPPVLLTPK 1349
Query: 715 LGPVPHEGLGEYNRAVSKLSAA-LSSLQRDMQRLTDQQQR--LLAPPEAPGSAPPPAAWV 771
P G G +S +S LS +D+ + + QR + PG
Sbjct: 1350 AVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPG--------- 1400
Query: 772 IPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKH-TRPAELRLAPLTRVLTPPHD 830
PG G +S P R PG G +S SPK+ +RP E R L PP
Sbjct: 1401 -PGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSS 1459
Query: 831 -----VDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAED 885
+D + H Q Q SS + P P +PGL + P G P
Sbjct: 1460 SAVFRLDQVIHSNPAGIQQALAQL-SSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRY 1518
Query: 886 E 886
E
Sbjct: 1519 E 1519
Score = 37.7 bits (86), Expect = 0.071
Identities = 39/145 (26%), Positives = 56/145 (38%), Gaps = 16/145 (11%)
Query: 858 ETPPEEPAARPGLIEI---PLGSLADPAAEDEGDGSPAGA-----EDSLEEEASSEGEPR 909
ET P PA +P L P G+ P + G P ED + +
Sbjct: 400 ETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSE 459
Query: 910 VGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRR-KQWQEVEKEQRREEAARLAQE 968
+ L + E+E + ER+ AE+ +R +++ +K + E AA A
Sbjct: 460 ISLAVERARRRREEEERRMQE----ERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAP 515
Query: 969 EAPGPAPLVSAVPMATPAPAARAPA 993
P P P AVP PAP A PA
Sbjct: 516 STPAPPP---AVPKELPAPPAPPPA 537
Score = 34.7 bits (78), Expect = 0.60
Identities = 26/65 (40%), Positives = 31/65 (47%), Gaps = 10/65 (15%)
Query: 758 PEAPGSAPPPAAWVIPGPTTGPK--AASPSPARRVPATRRSPGPG---PSQSPRSPKHTR 812
P AP APPP + + GP P A P PA PATR P P P+ R+ H
Sbjct: 1997 PPAPPPAPPPLSLLPVGPALQPPSLAVRPPPA---PATRVLPSPARPFPASLGRAELH-- 2051
Query: 813 PAELR 817
P EL+
Sbjct: 2052 PVELK 2056
Score = 33.5 bits (75), Expect = 1.3
Identities = 85/370 (22%), Positives = 113/370 (30%), Gaps = 77/370 (20%)
Query: 466 RPAPARTPTQP-PPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLA 524
RP R P P PP P + Q+IHS P + A S S P
Sbjct: 1441 RPPEERPPGLPLPPPPPSSSAVFRLDQVIHS-NPAGIQQALAQLSSRQGSVTAPGGHPRH 1499
Query: 525 SPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKP----PAPS-EGSPKAVA 579
P LP+ P P P T +P G +S P P P G
Sbjct: 1500 KPGLPQAPQGP-----------SPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPR 1548
Query: 580 SSPAATNSEVKMTSFAERKKQLVKAE------AEAGAGSPTSTPAP-PEALSSEMSELSA 632
S + K RK +L++ E + GS P P E+ + L+
Sbjct: 1549 DSAGVSPFPPKRRERPPRKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTP 1608
Query: 633 RLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREA----SGEAEAEAEEADSGPV 688
+ + ++K + + L S F V E SG + + SGP
Sbjct: 1609 HIWNRLHTATSRKSYRPSSMEPWMEPL--SPFEDVAGTEMSQSDSGVDLSGDSQVSSGPC 1666
Query: 689 PGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLT 748
P G +G PK S L VP EG
Sbjct: 1667 SQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEG-------------------------- 1700
Query: 749 DQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGP-GPSQSPRS 807
P P PPPA P G + P R P PGP G +S R+
Sbjct: 1701 -------PPGSEPPRRPPPA------PHDGDRKELP---REQPL---PPGPIGTERSQRT 1741
Query: 808 PKHTRPAELR 817
+ T P +R
Sbjct: 1742 DRGTEPGPIR 1751
Score = 32.3 bits (72), Expect = 3.0
Identities = 78/372 (20%), Positives = 116/372 (31%), Gaps = 57/372 (15%)
Query: 517 GPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGS-- 574
GP + S P+ S+P +RP P P P PP PS +
Sbjct: 1424 GPGRGDKRSWPSPKNRSRPPEERP------------PGLPLP--------PPPPSSSAVF 1463
Query: 575 --PKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSA 632
+ + S+PA + S + A G P P P+A
Sbjct: 1464 RLDQVIHSNPAGIQQALAQLSSRQ-------GSVTAPGGHPRHKPGLPQAPQGPSPRPPT 1516
Query: 633 RLEEKR--------RAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEAD 684
R E +R E + + R G S F + + E EE+
Sbjct: 1517 RYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKPELLQEESL 1576
Query: 685 SGPVPG---GERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQ 741
P G +P G G + +P + + A S+ S SS++
Sbjct: 1577 PPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHI-------WNRLHTATSRKSYRPSSME 1629
Query: 742 RDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGP 801
M+ L+ + +A E S ++GP + SP + P P
Sbjct: 1630 PWMEPLSPFED--VAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRP 1687
Query: 802 SQSPRSPKHTRPAE--LRLAPLTRVLTPPHDVD--SLPHLRKFSPSQVPVQTRSSILLAE 857
S SP + P E P R PHD D LP + P + +
Sbjct: 1688 GGS--SPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGT 1745
Query: 858 ETPPEEPAARPG 869
E P P+ RPG
Sbjct: 1746 EPGPIRPSHRPG 1757
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 60.5 bits (145), Expect = 1e-08
Identities = 149/621 (23%), Positives = 212/621 (34%), Gaps = 110/621 (17%)
Query: 434 FSTPFGLDSD-VDVVMGDPVLLRSVSSDSLGPPRPAPARTPTQPPPEPGDLPTIEEALQI 492
+S +GL S VD + P + +V+ P P + Q P P A +
Sbjct: 1851 YSPDYGLPSPKVDALHCPPAAVVTVT------PSPEGVFSSLQAKPSPSP-----RAELL 1899
Query: 493 IHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPET 552
+ S E L PD + P +PS P L EG P S T+ PV HP
Sbjct: 1900 VPSLEGALPPDLDTSEDQQATAAIIPPEPSYLEP-LDEG---PFSAVITEEPVEWAHPSE 1955
Query: 553 PSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVK---AEAEAG 609
+ S + G + P + GS + SP K A+ + +EA
Sbjct: 1956 QALASSLIGGTSENPVSWPVGS-DLLLKSPQRFPESPKRFCPADPLHSAAPGPFSASEAP 2014
Query: 610 AGSPTSTPAP---------PEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLG 660
+P ++PAP E + + + A + A A +E+ F+ +
Sbjct: 2015 YPAPPASPAPYALPVAEPGLEDVKDGVDAVPAAISTSEAAPYAPPSGLESFFSNCKSL-- 2072
Query: 661 KSAFLQVQPREASGEAEAEAE---EADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGP 717
A L V P A A A+ E ++ + G + GQ EP P A F+ GP
Sbjct: 2073 PEAPLDVAPEPACVAAVAQVEALGPLENSFLDGSRGLSHLGQVEPV--PWADAFA---GP 2127
Query: 718 VPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQ----QRLLAPPEAPGSAPPPAAWVIP 773
LG + +L L + D + + LAPPE PP A VI
Sbjct: 2128 EDDLDLGPF---------SLPELPLQTKDAADGEAEPVEESLAPPE---EMPPGAPGVIN 2175
Query: 774 GPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDS 833
G A PA P S R P P L L + ++
Sbjct: 2176 GGDVSTVVAEEPPAL----------PPDQASTRLPAELEPEPSGEPKLDVALEAAVEAET 2225
Query: 834 LPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEG-DGSPA 892
+P R V+ PPE+ PLGS D AE EG +
Sbjct: 2226 VPEERARGDPDSSVE-------PAPVPPEQR---------PLGS-GDQGAEAEGPPAASL 2268
Query: 893 GAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLER------QQRRAE---- 942
A D ++ + G G PED+ RA+ Q AE
Sbjct: 2269 CAPDGPAPNTVAQAQAADGAG--------PEDDTEASRAAAPAEGPPGGIQPEAAEPKPT 2320
Query: 943 -EARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAARAPAE------- 994
EA + + +E+ + R A LA + GP P TPAP RA A
Sbjct: 2321 AEAPKAPRVEEIPQRMTRNRAQMLANQSKQGPPPSEKEC-APTPAPVTRAKARGSEDDDA 2379
Query: 995 EEVGPRKGDFTRQEYERRAQL 1015
+ PRK F R + + QL
Sbjct: 2380 QAQHPRKRRFQRSTQQLQQQL 2400
Score = 46.2 bits (108), Expect = 2e-04
Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 38/225 (16%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
PP A R P + PEP P ++ AL+ + E +P+ A G P+ +P+
Sbjct: 2191 PPDQASTRLPAELEPEPSGEPKLDVALEA--AVEAETVPEERARG-----DPDSSVEPAP 2243
Query: 524 ASPY---LPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVG---------EASKPPAPS 571
P L G ++ P A + P P+ + EAS+ AP+
Sbjct: 2244 VPPEQRPLGSGDQGAEAEGPPAASLCAPDGPAPNTVAQAQAADGAGPEDDTEASRAAAPA 2303
Query: 572 EGSPKAV---ASSPAATNSEVKMTSFAERKKQLVKAEAEAGA-----GSPTS------TP 617
EG P + A+ P T K E +++ + A+ A G P S TP
Sbjct: 2304 EGPPGGIQPEAAEPKPTAEAPKAPRVEEIPQRMTRNRAQMLANQSKQGPPPSEKECAPTP 2363
Query: 618 APPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKS 662
AP + SE ++ +A +KRR + + +Q+L S
Sbjct: 2364 APVTRAKARGSE-----DDDAQAQHPRKRRFQRSTQQLQQQLNTS 2403
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 60.1 bits (144), Expect = 1e-08
Identities = 134/527 (25%), Positives = 168/527 (31%), Gaps = 109/527 (20%)
Query: 360 ASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLR-GSTGSLKSSPSMSHMEALGK 418
AS RG A P +N S P+ S G R G G S A GK
Sbjct: 87 ASGRGERAPPAKNTSPG---------PVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137
Query: 419 AWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRS--VSSDSLGPPRPAPARTP--- 473
A LS T S P + R + +G PRPAP+ P
Sbjct: 138 ATEAPKRSALSAGARRDT-----SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Query: 474 ----------------TQPPPEPGDLPTIEEALQ------IIHSAEPRLLPDGAADGSFY 511
T+P P P+ LQ + SA P P A G
Sbjct: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP--ARSGPSA 250
Query: 512 LHSPEGPSKPSLASPYLPEGTSKPLSDRPTK--APVYMPHPETP-SKPSPCLVGEASKPP 568
+P P+ PS P + P P K AP P +P + PSP S PP
Sbjct: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP------SAPP 304
Query: 569 APSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAP--PEAL--- 623
+PS SP AT TS Q + + SP +TP P P AL
Sbjct: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364
Query: 624 ----------SSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREAS 673
S +S L+ + A+ ++A F+ P +A
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHL--LQAPFSPPPS----------PPVQAP 412
Query: 674 GEAEAEAEEADSGPVPGGERP--AGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVS 731
A + S P P A P S P + SP P P A
Sbjct: 413 FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---APPPLAAP 469
Query: 732 KLSAALSSLQRDMQRLTDQQQRLLAPPEA-PGSAP-------PPAAWVIPGPTTGPKAAS 783
L A Q T Q L +PP + PG AP P + P P P A+
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529
Query: 784 P----------SPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAP 820
P SP + P RR P PGP S P+ T L LAP
Sbjct: 530 PLLQVPPSPPASPTLQAP--RRPPTPGPDTSVSGPRLT----LALAP 570
Score = 54.3 bits (129), Expect = 7e-07
Identities = 177/782 (22%), Positives = 249/782 (31%), Gaps = 146/782 (18%)
Query: 464 PPRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSL 523
P AP +PP P P + A + A + A+ + + G + P
Sbjct: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG---GATIPES 73
Query: 524 ASPYLPEGTSKP-LSDRPTKAPVYMPHPETPSKPSPCLV-GEASKPPAPSEGSPKAVASS 581
A P TS+P S R +AP P + P P G AS P K + S
Sbjct: 74 APRAGPTRTSRPPASGRGERAP-----PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128
Query: 582 PAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARL------- 634
T + K T +R A + +P TP+P A S + L
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLPRPAPSA 187
Query: 635 ------EEKRRAIEAQKRR--IEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSG 686
E R+++ + E A R+ + R S A + A SG
Sbjct: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247
Query: 687 PVPGG--ERPAGEGQGEPTS----RPKAVT-----FSPDLGPVPHEGLGEYNRAVSKLSA 735
P G PA Q +P RP VT +P LGP+ L + + +
Sbjct: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307
Query: 736 ALSSLQR----------------DMQRLTDQQQRLLAPPEAPGSAPPPAA---------W 770
A SLQ L L +PP +P + PPP A
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367
Query: 771 VIPGPTTGPKA---ASPSP------ARRVPATRRSPGPGPS-QSPRSPKHTRPAELRLAP 820
P P P A+PSP A + SP P P Q+P SP + P P
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427
Query: 821 LTR----VLTPPHDV-DSLPHLRKFSPS-----QVPVQTRSSILLAEETPPEEPAARPGL 870
++ + PP V S P SPS Q P + L + PP+ P P L
Sbjct: 428 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP---PAL 484
Query: 871 IEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKR 930
PL +L P A G +P SL + P+ P A
Sbjct: 485 ATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 931 ASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSAVPMATPAPAAR 990
R + RL APGP P P +R
Sbjct: 544 LQAPRRPPTPGPDT--------------SVSGPRLTLALAPGP-----------PPPPSR 578
Query: 991 APAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRAAGSGGPGRGGRRATRP---RS 1047
+P+ GP + +L+ D GP GG A+ P
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYD-------------SGP-EGGAAASPPPDAEL 624
Query: 1048 GCCDDSALARSPA-----RGLLGSRL---SKIYSQSTLSLSTVANEAHNNLGVKRPTSRA 1099
C +A +R PA RG G+ L S L T+ + P S
Sbjct: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE-------TEGPESAT 677
Query: 1100 PSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLYKEPSAKSNKFIIHNALSHC 1159
P+P G + P PG+ G+ A + + P+ RL + P ++ + LS
Sbjct: 678 PAP-GALDPGPSPGTSGGKAAAGAGAGASSRSPKQA--RLGELPLGALQASVVQHLLSRT 734
Query: 1160 CL 1161
L
Sbjct: 735 LL 736
Score = 43.5 bits (101), Expect = 0.001
Identities = 88/365 (24%), Positives = 126/365 (34%), Gaps = 72/365 (19%)
Query: 552 TPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAG 611
TP+ +P L+ +PP GSP+ P T + +++ A + AE G G
Sbjct: 16 TPAARAPGLL--TPRPP----GSPRP---PPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 612 SPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQR-------LGKSAF 664
T + P A + S A RA A+ + + R LG+
Sbjct: 67 GATIPESAPRAGPTRTSRPPAS-GRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125
Query: 665 -LQVQPREASGEA---------EAEAEEADSGPVPGGERPA--------GEGQGEPTSRP 706
+ + A G+A A A SGP PG PA G G P P
Sbjct: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 707 KAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPP 766
A P GP ++VS S T+ P A G
Sbjct: 186 SARPRPPTEGP---------RKSVSSASE---------HSTTEPSPAARRRPSAGGGLQR 227
Query: 767 PAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLT 826
PA+ + T SPAR P+ R +P ++P P +P L+ +V T
Sbjct: 228 PASRSLSSSAT----PLSSPARSGPSARGTP-----RAPAHPSQPKPKGLQALRPPQV-T 277
Query: 827 PPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDE 886
PP D+ P L S S + + S+ P P+A P L +P P+
Sbjct: 278 PPRK-DAAPALGPLSSSPLATPSPSA--------PPSPSAPPSLQTLPSPPATPPSQATT 328
Query: 887 GDGSP 891
GSP
Sbjct: 329 SLGSP 333
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 60.1 bits (144), Expect = 1e-08
Identities = 107/465 (23%), Positives = 176/465 (37%), Gaps = 63/465 (13%)
Query: 563 EASKPPAPSEGSPKAVASSP----AATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA 618
+ + P A P++ ++SP + T S + ER + + + AG GSP
Sbjct: 350 DRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGE---RRKPNAG-GSPAPVRR 405
Query: 619 PPEALSSEMSELS--ARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEA 676
PEA + E R EK ++ A++R + K RQ L S ++ AS E
Sbjct: 406 RPEASPVQKKEKKDKERENEKEKSALARERSL-----KKRQSLPASPRARLSASTAS-EL 459
Query: 677 EAEAEEADSGPVPGGERPA------GEGQGEPTS--RPKAVTFSPDLGPVPHEGLGEYNR 728
+++ S P RPA G G P P+ T SP +G
Sbjct: 460 SPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASP-------KGRVRRKE 512
Query: 729 AVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPAR 788
+ +A + + ++ A P +P +P P+ P P A +P+ A
Sbjct: 513 EAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPTDAA 572
Query: 789 RVPATRRSPGPGPSQSPRSPKH-TRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPV 847
+ + P P P +P P T E TR+L R+ + Q
Sbjct: 573 VLTSP---PAPAPPVTPSKPMAGTTDRE----EATRLLAEK---------RRQAREQRER 616
Query: 848 QTRSSILLAEETPP--EEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSE 905
+ + L AE EE AR A+ AE E + E E+A +E
Sbjct: 617 EEQERRLQAERDKRMREEQLARE----------AEARAEREAEARRR-EEQEAREKAQAE 665
Query: 906 GEPRVGLGFFYKDEDKPEDEMAQKRASLLER--QQRRAEEARRRKQWQEVEKEQRREEAA 963
E + L ++ + E A+++ E+ QQ+ E RRK+ +E+ K R+ E +
Sbjct: 666 QEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVS 725
Query: 964 RLAQEEAPGPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQE 1008
Q++ A + P A AR+P ++ +K + QE
Sbjct: 726 ETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIPQE 770
Score = 54.7 bits (130), Expect = 6e-07
Identities = 135/580 (23%), Positives = 200/580 (34%), Gaps = 88/580 (15%)
Query: 465 PRPAPARTPTQPPPE-----PGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPS 519
PRP+P P+ PPP P P A++ S++ L SP G
Sbjct: 25 PRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEP---------ESPSGQV 75
Query: 520 KPSLASPYLPEGTSKPLSDRPTKAPVYMPH----PETPSKPSPCLVGEASKPPAPSEGSP 575
P A P +S+ S PT P P P S+PSP V + PP E
Sbjct: 76 GPRPAPPQEESPSSEAKSRGPTP-PAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEVKK 134
Query: 576 KAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLE 635
A E + A +K ++ E +A A ++ E RLE
Sbjct: 135 AGERHKLAKERREERAKYLAAKKAVWLEKEEKAKA-----------LREKQLQERRRRLE 183
Query: 636 EKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPA 695
E+R ++A++RR A+ + RQ+L K+ + EA+ + + A+ +R +
Sbjct: 184 EQR--LKAEQRR-AALEERQRQKLEKNK----ERYEAAIQRSVKKTWAEIRQ----QRWS 232
Query: 696 GEG---QGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAAL---SSLQRDMQRLTD 749
G P + S +P N+ +SK SA L S R +Q
Sbjct: 233 WAGALHHSSPGHKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAW 292
Query: 750 QQQRL--LAPPEAPGSAPPPAAWVIP--------------GPTTGPKAAS----PSPARR 789
+ + L P A +A +P GPT G AS P P R
Sbjct: 293 ESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGCDPGRGPTWGRAGASLARGPQPDRT 352
Query: 790 VPATRRSPGP-GPSQSPRSPKHTRPAELRLAPL-TRVLTPPHDVDSLPHLRKFSPSQVPV 847
P+ P S SP +P + R AP R + P + P PV
Sbjct: 353 HPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPV 412
Query: 848 QTRSSILLAEETPPEEPA--------ARPGLIEIPLGSLADPAAED---EGDGSPAGAED 896
Q + E E+ A R L P L+ A + + P+
Sbjct: 413 QKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPST 472
Query: 897 SLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKE 956
S AS P G P+ + + + + RR EEA+ E +
Sbjct: 473 SWHRPASPCPSPGPGHTL------PPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDK 526
Query: 957 QRREEAARLAQEEAPGPAPLVSAVPMATPAPAAR--APAE 994
+ + A +E A +P S P TPAP + PAE
Sbjct: 527 SQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAE 566
Score = 54.7 bits (130), Expect = 6e-07
Identities = 99/402 (24%), Positives = 158/402 (39%), Gaps = 65/402 (16%)
Query: 658 RLGKSAFLQVQPREASGEAEAEAEEADSGP--VPGGERPAGEGQGEPTS--RPKAVTFSP 713
R SA + V PR AS S P GER GE + +P + P V P
Sbjct: 351 RTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGER--GERR-KPNAGGSPAPVRRRP 407
Query: 714 DLGPVPHEGLGEYNRAVSKLSAALS---SLQRDMQRLTDQQQRL-------LAPPEAPGS 763
+ PV + + R K +AL+ SL++ + RL L+P
Sbjct: 408 EASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLSASTASELSPKSKARP 467
Query: 764 APPPAAWVIP---------GPTTGPKAASP-----SP---ARRVPATRRSPGP-GPSQSP 805
+ P +W P G T PK SP SP RR + SP GP
Sbjct: 468 SSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKS 527
Query: 806 RSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPA 865
+S + + AP + +P P ++ P++ P T +++L T P PA
Sbjct: 528 QSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETP--TDAAVL----TSPPAPA 581
Query: 866 ARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDE 925
P P+ D E+ + E+ E E R+ +D+ E++
Sbjct: 582 P-PVTPSKPMAGTTD--REEATRLLAEKRRQAREQREREEQERRLQAE---RDKRMREEQ 635
Query: 926 MAQKRASLLERQQRRAEEARRRKQWQEVEKEQ-RREEAARLAQEEAPGPAPLVSAVPMAT 984
+A++ + ER+ EARRR++ + EK Q +EE RL +++ A
Sbjct: 636 LAREAEARAEREA----EARRREEQEAREKAQAEQEEQERLQKQKEEAEA---------- 681
Query: 985 PAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLR 1026
+R AE + R+ F +QE ER+ + K ++++ K R
Sbjct: 682 ---RSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTR 720
Score = 45.8 bits (107), Expect = 3e-04
Identities = 58/229 (25%), Positives = 83/229 (36%), Gaps = 26/229 (11%)
Query: 465 PRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLA 524
P P P T PP P T ++ E + P A PE S+
Sbjct: 482 PSPGPGHTLPPKPPSPRGT-TASPKGRVRRKEEAKESPSAAG--------PEDKSQSKRR 532
Query: 525 SPYLPEGTSKPLSDRPTKAPVYMPHP---ETPSKPSPCLVGEASKPPAPSEGSPKAVASS 581
+ E + P S P+ AP P P E P +P + PPAP +P S
Sbjct: 533 ASNEKESAA-PASPAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAP---APPVTPSK 588
Query: 582 PAA--TNSEVKMTSFAERKKQL----VKAEAEAGAGSPTSTPAPPEALSSEMSELSARLE 635
P A T+ E AE+++Q + E E + E L+ E + R
Sbjct: 589 PMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERDKRMREEQLAREAEARAEREA 648
Query: 636 EKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEAD 684
E RR E + R + ++RL K Q + EA EAE + +
Sbjct: 649 EARRREEQEAREKAQAEQEEQERLQK----QKEEAEARSREEAERQRLE 693
Score = 38.1 bits (87), Expect = 0.054
Identities = 49/203 (24%), Positives = 71/203 (34%), Gaps = 24/203 (11%)
Query: 767 PAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQS--PRSPKHTRPAELRLAPLTRV 824
P A + G A +P R P SP P P + P +P T PA ++
Sbjct: 5 PRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQL 64
Query: 825 LTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPL-GSLADPAA 883
P + P P Q S A+ P PA P P S P A
Sbjct: 65 PLEPESPSG-----QVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTA 119
Query: 884 EDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQR---- 939
D P E E + R ++ +A K+A LE++++
Sbjct: 120 VPASDSPPTKQEVKKAGERHKLAKER---------REERAKYLAAKKAVWLEKEEKAKAL 170
Query: 940 ---RAEEARRRKQWQEVEKEQRR 959
+ +E RRR + Q ++ EQRR
Sbjct: 171 REKQLQERRRRLEEQRLKAEQRR 193
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 59.7 bits (143), Expect = 2e-08
Identities = 118/440 (26%), Positives = 169/440 (38%), Gaps = 65/440 (14%)
Query: 512 LHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPS 571
L E +P LAS E +P P+K+ + P PSP VG+ S P P+
Sbjct: 279 LRREEPDLQPQLAS----EAPRRPAQPPPSKSALLPP-------PSP-RVGKRSPPGPPA 326
Query: 572 EGSPKAVASSPAATNSEVKM---TSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMS 628
+ P A +SP E + T+ E++ + K+ + AG+ S P P LS
Sbjct: 327 Q--PAATPTSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQTP--LSEASG 382
Query: 629 ELSARLEEKRRAIEAQKRRIEAI--FAKHRQRLGKS----AFLQ--VQPREASGEAEAEA 680
LSA L R + A R ++ + F + R+ L +S A L+ V R+A + ++
Sbjct: 383 RLSA-LGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAPLRPWVPLRKARSLEQPKS 441
Query: 681 EEADSGPVPGGERPAGEGQGEPTSR-----PKAVTF---------SPDLGPVPHEGLGEY 726
E PG + G R KA + + DL + LG
Sbjct: 442 ERGAPWGTPGASQEELRAPGSVAERRRLFQQKAASLDERTRQRSPASDLELRFAQELGRI 501
Query: 727 NRAVSK--LSAALSSLQRDMQRLTDQQQR----LLAPPEAPGS--APPPAAWVIPGPTTG 778
R+ S+ L + SL+ +QR ++ L + P P + A PAA P P++
Sbjct: 502 RRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSA 561
Query: 779 PKAASPS--PARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPH 836
K P R PA R PG GP Q R R R PP D
Sbjct: 562 EKPGDEPGRPRSRGPAGRTEPGEGPQQEVRRRDQFPLTRSRAIQECRSPVPPPAADPPEA 621
Query: 837 LRKFSPSQVPVQTRSSI-LLAEETPPEEPAARPGLIEIPLGSLADPAAE------DEGDG 889
K P + ++ L TP E AA P +E + A P AE E DG
Sbjct: 622 RTKAPPGRKREPPAQAVRFLPWATPGLEGAAVPQTLE---KNRAGPEAEKRLRRGPEEDG 678
Query: 890 SPAGAEDSLEEEASSEGEPR 909
P G D A S+G+ R
Sbjct: 679 -PWGPWD--RRGARSQGKGR 695
Score = 47.0 bits (110), Expect = 1e-04
Identities = 168/711 (23%), Positives = 245/711 (34%), Gaps = 112/711 (15%)
Query: 502 PDGAADGSFYLHSPEGPSKPSLASPYLPE--GTSKPLSDRPTKAPVYMPHPETPSKP--- 556
P G S E PS+ P PE G+ L+D PT+ + PET +
Sbjct: 1914 PSGGLSSSSDSEEEELEELPSVPRPLQPEFSGSRVSLTDIPTEDEA-LGTPETGAATPMD 1972
Query: 557 ------SPCLVGEASKPPA-PSEGSPKAVASSPAATNSEVKMTSFAERK-KQLVKAEAEA 608
+P EA P A PS G A +SP E++ S AE + E
Sbjct: 1973 WQEQGRAPSQDQEAPSPEALPSPGQEPAAGASPR--RGELRRGSSAESALPRAGPRELGR 2030
Query: 609 GAGSPTSTPAPPEALSSEMSELSAR--LEEKRRAIEAQKRRIEAIFAKHRQRL------- 659
G S P S + AR L E A +R++A+ RQRL
Sbjct: 2031 GLHKAASVELPQRRSPSPGATRLARGGLGEGEYA-----QRLQAL----RQRLLRGGPED 2081
Query: 660 GKSAFLQVQPREASGEAEAE---AEEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLG 716
GK + L+ E+ G + A A S P + P E K+ +FS
Sbjct: 2082 GKVSGLRGPLLESLGGRARDPRMARAASSEAAPHHQPPL-----ENRGLQKSSSFSQGEA 2136
Query: 717 PVPHEGLGEYNRA-------VSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAA 769
E G + RA V++L A + L++ Q A P AP + P +A
Sbjct: 2137 ----EPRGRHRRAGAPLEIPVARLGARRLQESPSLSALSEAQPSSPARPSAPKPSTPKSA 2192
Query: 770 WVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLTPPH 829
P A +PS A + PA + + P P + ++PA A T L
Sbjct: 2193 --------EPSATTPSDAPQPPAPQPAQDKAPEPRPEPVRASKPAPPPQALQTLALPLTP 2244
Query: 830 DVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEGDG 889
+ L+ +Q P Q PP EP +P + P A ++
Sbjct: 2245 YAQIIQSLQLSGHAQGPSQ-------GPAAPPSEP--KPHAAVFARVASPPPGAPEKRVP 2295
Query: 890 SPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKP-----EDEMAQKRASLLERQQRRAEEA 944
S G E+ PR G E+ E + + R S L R +
Sbjct: 2296 SAGGPPVLAEKARVPTVPPRPGSSLSSSIENLESEAVFEAKFKRSRESPLSLGLRLLSRS 2355
Query: 945 R--RRKQWQEVEKEQ---------------RREEAARLAQE-EAPGPAPLVSAVPMA--- 983
R R ++ E+E RR E +R Q+ A G LV + ++
Sbjct: 2356 RSEERGPFRGAEEEDGIYRPSPAGTPLELVRRPERSRSVQDLRAVGEPGLVRRLSLSLSQ 2415
Query: 984 ----TPAPAARAPAEEEVG-----PRKGDFTRQEYERRAQLKLMDDLDKV-LRPRAAGSG 1033
TP PA R PA E G G R + +L L+++ R + +GS
Sbjct: 2416 RLRRTP-PAQRHPAWEARGGDGESSEGGSSARGSPVLAMRRRLSFTLERLSSRLQRSGSS 2474
Query: 1034 GPGRGGRRATRPRSGCCDDSALARSPARGLLGSRLSKIYSQSTLSLSTVANEAHNNLGVK 1093
G + P G L R+ + G RL ++Q A +
Sbjct: 2475 EDSGGASGRSTPLFG-----RLRRATSEGESLRRLGLPHNQLAAQAGATTPSAESLGSEA 2529
Query: 1094 RPTSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPEYTGPRLYKEPS 1144
TS + +P S R SR R + S + ASV E G + + S
Sbjct: 2530 SATSGSSAPGESRSRLRWGFSRPRKDKGLSPPNLSASVQEELGHQYVRSES 2580
Score = 45.4 bits (106), Expect = 3e-04
Identities = 94/370 (25%), Positives = 137/370 (37%), Gaps = 69/370 (18%)
Query: 728 RAVS-KLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGP-KAASPS 785
RA+S +S S L+R+ L Q Q P P PP + ++P P+ K + P
Sbjct: 266 RALSIHVSVPQSGLRREEPDL--QPQLASEAPRRPAQPPPSKSALLPPPSPRVGKRSPPG 323
Query: 786 PARRVPATRRSPGPGPSQSPRSPKHTRPAELR----------LAPL--TRVLTPPHDVDS 833
P + AT SP +Q P P+ T E R LA +R TP +
Sbjct: 324 PPAQPAATPTSPHRR-TQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESRPQTPLSEASG 382
Query: 834 LPHLRKFSPSQVPV-----------QTRSSILLAEETPPEEPAARPGLIEIPLGSLADPA 882
SP V + R L ++PP RP + SL P
Sbjct: 383 RLSALGRSPRLVRAGSRILDKLQFFEERRRSLERSDSPPAP--LRPWVPLRKARSLEQPK 440
Query: 883 AEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAE 942
+E G+P G + +EE + G F + + DE ++R+ + + R A+
Sbjct: 441 SER---GAPWGTPGASQEELRAPGSVAERRRLF-QQKAASLDERTRQRSPASDLELRFAQ 496
Query: 943 EARRRKQWQEVEKEQRREEAARLAQEEAPGP-----APLVS--AVPMATPA--PAARAPA 993
E R ++ E+ R E+ R + AP P PL S + P + A PAA P
Sbjct: 497 ELGRIRRSTSREELVRSHESLRATLQRAPSPREPGEPPLFSRPSTPKTSRAVSPAAAQPP 556
Query: 994 EEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRAAGSGG---PGRGGRRATRPRSGCC 1050
+ G D+ RPR+ G G PG G ++ R R
Sbjct: 557 SPSSAEKPG-------------------DEPGRPRSRGPAGRTEPGEGPQQEVRRR---- 593
Query: 1051 DDSALARSPA 1060
D L RS A
Sbjct: 594 DQFPLTRSRA 603
Score = 44.3 bits (103), Expect = 8e-04
Identities = 60/231 (25%), Positives = 90/231 (38%), Gaps = 27/231 (11%)
Query: 703 TSRPKAVTFSPDLGPVPHEGLGEYNRAVSKL-------SAALSSLQRDMQRLTDQQQRLL 755
T P VT + G G ++ + K+ S+A+ S +T + R
Sbjct: 2736 THLPVGVTVRFRVACANRAGQGPFSNSSEKVFVRGTQDSSAVPSAAHQEAPVTSRPARA- 2794
Query: 756 APPEAPGSAPPPAAWVIPGP--TTGPKAASPSPARRVPATRRSPGPGPSQSPRSPK---H 810
PP++P S PP A P P T ++ P+P + ++ ++ GP P PR +
Sbjct: 2795 RPPDSPTSLAPPLAPAAPTPPSVTVSPSSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQA 2854
Query: 811 TRPAELRLAPLTRVLTP----PHDVD-------SLPHLRKFSPSQVPVQTRSSILLAEET 859
RPAE L P T V TP P +D S P K S PV +S + A
Sbjct: 2855 ARPAEPTL-PSTHV-TPSEPKPFVLDTGTPIPASTPQGVKPVSSSTPVYVVTSFVSAPPA 2912
Query: 860 P-PEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPR 909
P P P P ++ + SL+ GS + E +G P+
Sbjct: 2913 PEPPAPEPPPEPTKVTVQSLSPAKEVVSSPGSSPRSSPRPEGTTLRQGPPQ 2963
Score = 38.1 bits (87), Expect = 0.054
Identities = 73/310 (23%), Positives = 106/310 (34%), Gaps = 45/310 (14%)
Query: 404 LKSSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVLLRSVSSDSLG 463
L+ SPS+S AL +A +RP A STP + P +
Sbjct: 2161 LQESPSLS---ALSEAQPSSPARP--SAPKPSTPKSAEPSATTPSDAPQPPAPQPAQDKA 2215
Query: 464 P-PRPAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPS 522
P PRP P R ++P P P L T+ L L G A +GPS+
Sbjct: 2216 PEPRPEPVRA-SKPAPPPQALQTLALPLTPYAQIIQSLQLSGHA---------QGPSQGP 2265
Query: 523 LASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASK----PPAPS------- 571
A P P+ + + R P P PS P ++ E ++ PP P
Sbjct: 2266 AAPPSEPKPHAAVFA-RVASPPPGAPEKRVPSAGGPPVLAEKARVPTVPPRPGSSLSSSI 2324
Query: 572 ---------EGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEA 622
E K SP + + S +E + AE E G P+ P E
Sbjct: 2325 ENLESEAVFEAKFKRSRESPLSLGLRLLSRSRSEERGPFRGAEEEDGIYRPSPAGTPLEL 2384
Query: 623 LSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQP----REASGEAEA 678
+ E S +++ R + + + QRL ++ Q P R GE+
Sbjct: 2385 V--RRPERSRSVQDLRAV--GEPGLVRRLSLSLSQRLRRTPPAQRHPAWEARGGDGESSE 2440
Query: 679 EAEEADSGPV 688
A PV
Sbjct: 2441 GGSSARGSPV 2450
Score = 35.0 bits (79), Expect = 0.46
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 16/131 (12%)
Query: 510 FYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSP--CLVGEASKP 567
F + + + PS A P TS+P RP +P + P P+ P+P V +S P
Sbjct: 2767 FVRGTQDSSAVPSAAHQEAPV-TSRPARARPPDSPTSLAPPLAPAAPTPPSVTVSPSSPP 2825
Query: 568 PAPSE--GSPKAVASSP-----------AATNSEVKMTSFAERKKQLVKAEAEAGAGSPT 614
PS+ S KAV P AA +E + S + + G P
Sbjct: 2826 TPPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTGTPIPA 2885
Query: 615 STPAPPEALSS 625
STP + +SS
Sbjct: 2886 STPQGVKPVSS 2896
Score = 33.1 bits (74), Expect = 1.7
Identities = 83/355 (23%), Positives = 116/355 (32%), Gaps = 88/355 (24%)
Query: 802 SQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPP 861
S++PR P P++ L P PP P + K SP PP
Sbjct: 292 SEAPRRPAQPPPSKSALLP------PPS-----PRVGKRSPPG---------------PP 325
Query: 862 EEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDK 921
+PAA P + P ED+ EE + G E +
Sbjct: 326 AQPAATP-------------TSPHRRTQEPVLPEDTTTEEKRGKKSKSSGPSLAGTAESR 372
Query: 922 PEDEMAQK--RASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPAPLVSA 979
P+ +++ R S L R R R + +E+RR L + ++P PAPL
Sbjct: 373 PQTPLSEASGRLSALGRSPRLVRAGSRILDKLQFFEERRRS----LERSDSP-PAPLRPW 427
Query: 980 VPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLKLMDDLDKVLRPRAAGSGGPGRGG 1039
VP+ A + P E P QE RA GS R
Sbjct: 428 VPLRK-ARSLEQPKSERGAPWGTPGASQE-----------------ELRAPGSVAERR-- 467
Query: 1040 RRATRPRSGCCDDSALARSPARGL-------LG------SRLSKIYSQSTLSLSTVANEA 1086
R + ++ D+ RSPA L LG SR + S +L + +
Sbjct: 468 -RLFQQKAASLDERTRQRSPASDLELRFAQELGRIRRSTSREELVRSHESLRATLQRAPS 526
Query: 1087 HNNLG----VKRP----TSRAPSPSGLMSPSRLPGSRERDWENGSNASSPASVPE 1133
G RP TSRA SP+ PS + D + PA E
Sbjct: 527 PREPGEPPLFSRPSTPKTSRAVSPAAAQPPSPSSAEKPGDEPGRPRSRGPAGRTE 581
Score = 32.3 bits (72), Expect = 3.0
Identities = 54/249 (21%), Positives = 75/249 (30%), Gaps = 46/249 (18%)
Query: 458 SSDSLGPPRPAPARTPTQPPP---EPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHS 514
+ DS P A P P P D PT S P L P S +
Sbjct: 2771 TQDSSAVPSAAHQEAPVTSRPARARPPDSPT---------SLAPPLAPAAPTPPSVTVSP 2821
Query: 515 PEGPSKPSLA---------SPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEAS 565
P+ PS A P P + L P TPS+P P ++ +
Sbjct: 2822 SSPPTPPSQALSSLKAVGPPPQTPPRRHRGLQAARPAEPTLPSTHVTPSEPKPFVLDTGT 2881
Query: 566 KPPAPSEGSPKAVASS-----------------PAATNSEVKMTSFAERKKQLVKAEAEA 608
PA + K V+SS P A + T + K +
Sbjct: 2882 PIPASTPQGVKPVSSSTPVYVVTSFVSAPPAPEPPAPEPPPEPTKVTVQSLSPAKEVVSS 2941
Query: 609 GAGSPTSTPAPPEAL--SSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQ 666
SP S+P P + LEEK R R + A G++ +
Sbjct: 2942 PGSSPRSSPRPEGTTLRQGPPQKPYTFLEEKARG------RFGVVRACRENATGRTFVAK 2995
Query: 667 VQPREASGE 675
+ P A G+
Sbjct: 2996 IVPYAAEGK 3004
>gi|39930375 enabled homolog isoform b [Homo sapiens]
Length = 570
Score = 59.3 bits (142), Expect = 2e-08
Identities = 85/348 (24%), Positives = 129/348 (37%), Gaps = 67/348 (19%)
Query: 420 WNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPVL----LRSVSSDSLGPPRPAPARTPTQ 475
W R+ R +S A + P +++ ++ V+GD L++ S + P + P
Sbjct: 258 WERE--RRISSAAA---PASVETPLNSVLGDSSASEPGLQAASQPAETPSQQGIVLGPLA 312
Query: 476 PPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKPSLASPYLPE-GTSK 534
PPP P LP G A S L P GP P P LP G
Sbjct: 313 PPPPPP-------------------LPPGPAQASVALPPPPGPPPP----PPLPSTGPPP 349
Query: 535 PLSDRPTKAPVYMPHPETPSKPSPC---LVGEASKPPAPSEGSPKAVASSPAATNSEVKM 591
P P V P P P+ P P + S+ P G A+A + S ++
Sbjct: 350 PPPPPPLPNQVPPPPPPPPAPPLPASGFFLASMSEDNRPLTGLAAAIAGAKLRKVSRMED 409
Query: 592 TSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAI 651
TSF + A + + P S M E+SA L +RR E
Sbjct: 410 TSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMSALLARRRRIAE--------- 460
Query: 652 FAKHRQRLGKSAFLQVQPREASGE-AEAEAEEADSGPVPGGERPAGE------GQGEPT- 703
K + ++ + +E GE +E +A S P R E G P
Sbjct: 461 ---------KGSTIETEQKEDKGEDSEPVTSKASSTSTPEPTRKPWERTNTMNGSKSPVI 511
Query: 704 SRPKAVTFS-PDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQ 750
SRPK+ S P V EGL +Y+R + L +++++ +L ++
Sbjct: 512 SRPKSTPLSQPSANGVQTEGL-DYDRLKQDI---LDEMRKELTKLKEE 555
Score = 45.8 bits (107), Expect = 3e-04
Identities = 80/354 (22%), Positives = 122/354 (34%), Gaps = 46/354 (12%)
Query: 621 EALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEA 680
E L E E + E++ +E Q+R + ++RL + + Q RE E E
Sbjct: 184 ERLEQEQLERERQERERQERLERQERLERQERLERQERLDRER-QERQERERLERLERER 242
Query: 681 EEADSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 740
+E + E+ E + +S + L V LG+ + + L AA
Sbjct: 243 QERERQEQLEREQLEWERERRISSAAAPASVETPLNSV----LGDSSASEPGLQAASQPA 298
Query: 741 QRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPG 800
+ T QQ ++ P AP PP + PGP A P P P S GP
Sbjct: 299 E------TPSQQGIVLGPLAPPPPPP----LPPGPAQASVALPPPPGPPPPPPLPSTGPP 348
Query: 801 PSQSPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP 860
P P PL + PP P P S LA +
Sbjct: 349 PPPPP-------------PPLPNQVPPPP-----------PPPPAPPLPASGFFLASMSE 384
Query: 861 PEEPAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDED 920
P GL G+ + E P+G ASS+ + G G
Sbjct: 385 DNRPLT--GLAAAIAGAKLRKVSRMEDTSFPSGGNAIGVNSASSKTDTGRGNGPLPLGGS 442
Query: 921 KPEDEMAQKRASLLERQQRRAEEARRRKQWQEVEK-EQRREEAARLAQEEAPGP 973
+EM ++LL R++R AE+ + Q+ +K E ++ + P P
Sbjct: 443 GLMEEM----SALLARRRRIAEKGSTIETEQKEDKGEDSEPVTSKASSTSTPEP 492
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 59.3 bits (142), Expect = 2e-08
Identities = 137/595 (23%), Positives = 201/595 (33%), Gaps = 112/595 (18%)
Query: 515 PEGPSKPSLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPS--- 571
P P PS P P TS P P P P P P P S PP P+
Sbjct: 405 PLTPPAPSPPPPLPPPSTSPP--------PPLCPPPPPPVSPPPL----PSPPPPPAQEE 452
Query: 572 --EGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA-----PPEALS 624
E P V ++ + +T +++ +A E G PT TP+ PPE
Sbjct: 453 QEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE-GTSPPTPTPSTATGGPPEDSP 511
Query: 625 SEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEAD 684
+ + + L+ R+ I + + R+ K+ PR E + + +
Sbjct: 512 TVAPKSTTFLKNIRQF-------IMPVVSARSSRVIKT------PRRFMDEDPPKPPKVE 558
Query: 685 SGPV---PGGERPAGEGQGEPT-SRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSL 740
PV P P + P S P+A T P PVP L E R++ L
Sbjct: 559 VSPVLRPPITTSPPVPQEPAPVPSPPRAPT--PPSTPVP---LPEKRRSI---------L 604
Query: 741 QRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPK-------------------- 780
+ R T + L PP AP PPPA P P T +
Sbjct: 605 REPTFRWTSLTRELPPPPPAP--PPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIY 662
Query: 781 --AASPSPARRVPATRRSPGPGPSQSPRSPKHT---RPAELRLAPLTRVLTPPHDVDSLP 835
+P P A P P SP P+ R L L V+T P + P
Sbjct: 663 ESVLTPPPLGAPEAPEPEPPPA-DDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSP 721
Query: 836 H----LRKFSPSQV----PVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAAEDEG 887
H L +Q P+Q + LL + PP +P +P + L G
Sbjct: 722 HGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQMPPLEKARIAGVG 781
Query: 888 DGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPEDEMAQKRASLLERQQRRAEEARRR 947
+G E+ + R + F D+ + + A S + + A ++
Sbjct: 782 SLPLSGVEEKMFSLLK-----RAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQI 836
Query: 948 KQWQEVEKEQRREEA--ARLAQEEAPGPAPLVSAV--PMATPAPAARAPAEEEVGPR--- 1000
V E EA R + E+P P + V A ARA E+V PR
Sbjct: 837 SDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDV-PRLSA 895
Query: 1001 -----KGDFTRQEYERRAQLKLMDDLDKVLRPRAAGSGG----PGRGGRRATRPR 1046
+ D ++ ++ + + + + AAG GG G GG A PR
Sbjct: 896 LPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGESEPTGSGGTLAHTPR 950
Score = 47.0 bits (110), Expect = 1e-04
Identities = 127/555 (22%), Positives = 189/555 (34%), Gaps = 115/555 (20%)
Query: 361 SPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLKSSPSMSHMEALGKAW 420
S R + G+S P T P ++GGP P T + KS+ + ++
Sbjct: 477 SQRAEREAARAGPEGTSPPTPT---PSTATGGP--PEDSPTVAPKSTTFLKNI------- 524
Query: 421 NRQLSRPLSQAVS---FSTPFG-LDSDVDV---VMGDPVLLRSVSSDSLGPPRPAPARTP 473
RQ P+ A S TP +D D V PVL +++ P PAP +P
Sbjct: 525 -RQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSP 583
Query: 474 TQPPPEPG-DLPTIEEALQIIH------SAEPRLLPDGAADGSFYLHSPEGPSKPSLASP 526
+ P P +P E+ I+ ++ R LP P P P SP
Sbjct: 584 PRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPP----------PPPAPPPPPAPSP 633
Query: 527 YLPEGTSKPLSDRP--TKAPVYMPHP------ETPSKPSPCLVGEASKP-PAPSEGSPKA 577
TS S RP +AP + P E+ P P EA +P P P++ SP
Sbjct: 634 PPAPATS---SRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEPPPADDSPAE 690
Query: 578 VASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEK 637
+ + + FA VKAE SP PA S + A+L +
Sbjct: 691 PEPRAVGRTNHLSLPRFAPVVTTPVKAEV-----SPHGAPA-----LSNGPQTQAQLLQP 740
Query: 638 RRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGE 697
+A++ Q +A P P + P
Sbjct: 741 LQALQTQL----------------------------------LPQALPPPQPQLQPPPSP 766
Query: 698 GQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAP 757
Q P + + +G +P G+ E K+ + L + + ++ QQQ+ +A
Sbjct: 767 QQMPPLEKARIA----GVGSLPLSGVEE------KMFSLLKRAKVQLFKIDQQQQQKVAA 816
Query: 758 --PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAE 815
P +PG A + + S + R S P Q PR R A
Sbjct: 817 SMPLSPGGQMEEVAGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAA 876
Query: 816 LRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPL 875
+ L ++ P DV L L + + SS A ET +R G +E
Sbjct: 877 VALGQARAMV--PEDVPRLSALPLRDRQDLATEDTSS---ASETESVPSRSRRGKVE--- 928
Query: 876 GSLADPAAEDEGDGS 890
A P E E GS
Sbjct: 929 --AAGPGGESEPTGS 941
Score = 47.0 bits (110), Expect = 1e-04
Identities = 98/424 (23%), Positives = 138/424 (32%), Gaps = 102/424 (24%)
Query: 473 PTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAAD----------GSFYLHSP----EGP 518
P P EP L EE I+HS P P G D G+ HSP + P
Sbjct: 1785 PWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPP 1844
Query: 519 SKPSLASPYLPEGTSKPLSDRPTKAPVY--------------MPHPETPSK--------- 555
+P S P + S K P Y +P P +PS
Sbjct: 1845 LRPDSGS--APPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVG 1902
Query: 556 ----PSPCLVGEASKPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAG 611
P+P P AP P AS P T+ ++++ L E
Sbjct: 1903 DPDFPAPPRRSRRPSPLAP-RPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPP 1961
Query: 612 SPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPRE 671
P +P PPE L + ++ + + + FA ++ L +P +
Sbjct: 1962 GPAPSPPPPEDLGPDFEDME---------VVSGLSAADLDFA--------ASLLGTEPFQ 2004
Query: 672 ASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSR----PKAVTFSPDLGPVPHEGLGEYN 727
E G GG + E + PTSR P V +P L P G
Sbjct: 2005 -----EEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPR-- 2057
Query: 728 RAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPG-------------SAPP---PAAWV 771
+ +L + + + Q + PP PG + PP P+ V
Sbjct: 2058 --IEQLDGVDDGTDSEAEAV-QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIV 2114
Query: 772 ------IPGP---TTGPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLT 822
+ GP GP+ S PA + A P G + SP P T A L AP
Sbjct: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPL-ANGSQPSQGLTASPADPTRTF-AWLPGAPGV 2172
Query: 823 RVLT 826
RVL+
Sbjct: 2173 RVLS 2176
Score = 45.4 bits (106), Expect = 3e-04
Identities = 81/362 (22%), Positives = 104/362 (28%), Gaps = 59/362 (16%)
Query: 459 SDSLGPPRPAPARTPTQPPPEPG------------DLPTIEEALQIIHSAEPRLLPDGAA 506
S S PP P P PPP P P + A P L P A
Sbjct: 421 STSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRA 480
Query: 507 DGSFYLHSPEGPSKPSLASPYLPEGTSKPLSDRPTKAP-----------VYMP------- 548
+ PEG S P +P T P D PT AP MP
Sbjct: 481 EREAARAGPEGTSPP---TPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSS 537
Query: 549 ---------HPETPSKPSPCLVGEASKPP----APSEGSPKAVASSPAATNSEVKMTSFA 595
E P KP V +PP P P V S P A
Sbjct: 538 RVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLP 597
Query: 596 ERKKQLVKAE----AEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAI 651
E+++ +++ P PAPP + A + + A +
Sbjct: 598 EKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEA 657
Query: 652 FAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGEPTSRPKAVTF 711
K + + L P A E E AD P R G R V
Sbjct: 658 HLKIYE-----SVLTPPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVT 712
Query: 712 SPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWV 771
+P V G A+S + L + +Q L Q PP P PPP+
Sbjct: 713 TPVKAEVSPHGA----PALSNGPQTQAQLLQPLQALQTQLLPQALPPPQPQLQPPPSPQQ 768
Query: 772 IP 773
+P
Sbjct: 769 MP 770
Score = 40.0 bits (92), Expect = 0.014
Identities = 42/166 (25%), Positives = 65/166 (39%), Gaps = 18/166 (10%)
Query: 758 PEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPG----PGPSQSPRSPKHTRP 813
P AP PPP+ W P T P+ P P V A + G PGP+ SP P+ P
Sbjct: 1918 PLAP--RPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
Query: 814 AELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETP----PEEPAARPG 869
+ ++ + D+D L P Q + ++ + P EE +
Sbjct: 1976 DFEDMEVVSGLSAA--DLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSR 2033
Query: 870 LIEIPLGSLADPA-AEDEGDGSPA-----GAEDSLEEEASSEGEPR 909
I P+ ++ P A G+P G +D + EA + +PR
Sbjct: 2034 YIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPR 2079
Score = 35.4 bits (80), Expect = 0.35
Identities = 114/547 (20%), Positives = 171/547 (31%), Gaps = 119/547 (21%)
Query: 455 RSVSSDSLGPPR-----PAPARTPTQPPPEPGDLPTIEEALQIIHSAEPRLLPDGAADGS 509
R + L PPR P P +TP + E G ++ +++ A+ P A
Sbjct: 154 RKHKTTPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRAC-- 211
Query: 510 FYLHSPEGPSKPSLASPYLPEGTSKPLSDRPT--KAPVYMPHPETPSKPSPCLVGEAS-- 565
P P + P P G + +A V +P PE P P S
Sbjct: 212 ----EPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWK 267
Query: 566 --KPPAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEAL 623
+ P P G+P+ S G G P A
Sbjct: 268 CKEGPGPGPGTPRRGGQSSRGGRGG---------------RGRGRGGGLPFVIKFVSRAK 312
Query: 624 SSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEA 683
+M +LS LE SG+ + + EE+
Sbjct: 313 KVKMGQLSLGLE-------------------------------------SGQGQGQHEES 335
Query: 684 DSGPVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRD 743
VP +R G GQG K D E + K A++ +
Sbjct: 336 WQD-VP--QRRVGSGQGGSPCWKKQEQKLDDEEEEKKEEEEKDKEGEEKEERAVA--EEM 390
Query: 744 MQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASPSPARRVPATRRSPGPGPSQ 803
M ++ +L PP P + PP +P P+T P P P P SP P PS
Sbjct: 391 MPAAEKEEAKLPPPPLTPPAPSPPPP--LPPPSTSP----PPPLCPPPPPPVSPPPLPSP 444
Query: 804 SPRSPKHTRPAELRLAPLTRVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEE 863
P P E +PP V + ++ P P Q E
Sbjct: 445 PP-PPAQEEQEE----------SPPPVVPATCSRKRGRPPLTPSQR-----------AER 482
Query: 864 PAARPGLIEIPLGSLADPAAEDEGDGSPAGAEDSLEEEASSEGEPRVGLGFFYKDEDKPE 923
AAR G P G+ G P ++ ++++ F K+ +
Sbjct: 483 EAARAG----PEGTSPPTPTPSTATGGPPEDSPTVAPKSTT----------FLKNIRQFI 528
Query: 924 DEMAQKRASLLERQQRR-AEEARRRKQWQEVEKEQRR--EEAARLAQEEAPGPAPLVSAV 980
+ R+S + + RR +E + EV R + + QE AP P+P +
Sbjct: 529 MPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPT 588
Query: 981 PMATPAP 987
P +TP P
Sbjct: 589 PPSTPVP 595
Score = 33.9 bits (76), Expect = 1.0
Identities = 50/210 (23%), Positives = 67/210 (31%), Gaps = 28/210 (13%)
Query: 669 PREASGEAEAEAEEAD--SGPVPGGERPAGEGQ---------GEPTSRPKAVTFSPDLGP 717
PRE EA E P P E P GE G P P L P
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRP 1847
Query: 718 VPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTT 777
R+ S + + + L P +PGS P++ PT
Sbjct: 1848 DSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVS---FGPLPSPGS---PSSLTHHIPTV 1901
Query: 778 GPKAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPLTRVLT----------P 827
G P R + +P P PS+ P T P +LR+ P T V+T P
Sbjct: 1902 GDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSP-QLRVPPPTSVVTALTPTSGELAP 1960
Query: 828 PHDVDSLPHLRKFSPSQVPVQTRSSILLAE 857
P S P P ++ S + A+
Sbjct: 1961 PGPAPSPPPPEDLGPDFEDMEVVSGLSAAD 1990
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 58.5 bits (140), Expect = 4e-08
Identities = 105/433 (24%), Positives = 147/433 (33%), Gaps = 88/433 (20%)
Query: 607 EAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQ 666
E G G T A P L+ + SELS L+ + + + ++ +G +
Sbjct: 570 ENGEGPAT---AGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARS--- 623
Query: 667 VQPREASGEAEAEAEEADSG--PVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLG 724
SG ++ + SG P P ER EG P PK + P GP P+ +
Sbjct: 624 ----RGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP---PKLCSSLPGQGPPPYVFMY 676
Query: 725 EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP 784
P +P PPP A GP A P
Sbjct: 677 PQGS-----------------------------PSSPAPGPPPGAPWAFSYLAGPPATPP 707
Query: 785 SPARRVPATRRSPGPGPSQSPRSPKHTRPAELRL---APLTR------------VLTP-- 827
P R + PGP++ + P L A LTR +TP
Sbjct: 708 DPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTP 767
Query: 828 ----PHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPP---EEPAARPGLIEIPLGSLAD 880
P R+ P P + SS+ PP E P + G +L++
Sbjct: 768 ARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSE 827
Query: 881 PAAEDEGDGSPAGA---EDSLEEEASSEGEP----RVGLGFFYKDEDKPEDEMAQKRASL 933
PA E G PA A D+ EEE EG P G G + +E + K A
Sbjct: 828 PAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 887
Query: 934 LERQQ----------RRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPA-PLVSAVPM 982
R+ ++ +RR + +E E Q A +A PGPA PL S P
Sbjct: 888 PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA-TPGPAAPLPSPTPG 946
Query: 983 ATPAPAARAPAEE 995
+P PA+ P E
Sbjct: 947 ESP-PASSLPQPE 958
Score = 57.4 bits (137), Expect = 9e-08
Identities = 120/479 (25%), Positives = 163/479 (34%), Gaps = 68/479 (14%)
Query: 346 PDFVQVKDLPDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLK 405
P Q ++LP+G P+ + P G P + F +P G P SP + G
Sbjct: 642 PSPPQERNLPEGTERPPKLCSSLP-----GQGPPPYVFMYP---QGSPSSP---APGPPP 690
Query: 406 SSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPV--LLRSVSSDSLG 463
+P A A RP ++ S S P + D + PV L S ++ +
Sbjct: 691 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR 750
Query: 464 PPRPAPARTPTQPPPEP--GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKP 521
P R A RT P P G + AL+ P P + S SPE P P
Sbjct: 751 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG--PSPEPP--P 806
Query: 522 SLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASS 581
SP EG + P R P P P P+ + P P EG+P + SS
Sbjct: 807 LDESPGPKEGATGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGP-EGTPPSRGSS 864
Query: 582 PAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAI 641
FAE +K + P TP PP + + + K R
Sbjct: 865 GEGL-------PFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRER 917
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGE 701
E + + A F G +A L P G E+ A S P P E + QG
Sbjct: 918 EPLQTALLA-FGVASATPGPAAPL---PSPTPG----ESPPASSLPQP--EPSSLPAQGV 967
Query: 702 PTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAP 761
PT + P + P P GL S+A S + + PP AP
Sbjct: 968 PTPLAPSPAMQPPVPPCPGPGLE---------SSAASRWNGETE-----------PPAAP 1007
Query: 762 GSAPPPAAWVIPGPTTGPKAASPSPARRV-----PATRRSPGPGPSQSPRSPKHTRPAE 815
A +PG T PK S + + A R P P P P S P +
Sbjct: 1008 A-----ALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQ 1061
Score = 56.2 bits (134), Expect = 2e-07
Identities = 120/501 (23%), Positives = 171/501 (34%), Gaps = 91/501 (18%)
Query: 455 RSVSSDSLGPPRPAPARTPTQPPPEP--GDLPTIEEALQIIHSAEPRLLPDGAADGSFYL 512
RS S +S+G + QP P+P GD +E R LP+G
Sbjct: 612 RSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE----------RNLPEGTERPPKLC 661
Query: 513 HSPEGPSKPSLASPYLPEGTSKPLSDRPTKAP---VYMPHPET--PSKPSPCLVGEASKP 567
S G P Y S P P AP Y+ P P P P +
Sbjct: 662 SSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSR 721
Query: 568 PAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA--------- 618
P P+EG + A P + + S+A ++ ++ + S T TPA
Sbjct: 722 PGPTEGDAEGEAEGPVGST----LGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSF 777
Query: 619 --------PPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQP- 669
PP +S +S E E+ + E R+ L + A P
Sbjct: 778 ALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPK-EGATGPRRRTLSEPAGPSEPPG 836
Query: 670 REASGEAEAEAEEADSGP--VPGGERPAGEG-----QGEPT--SRPKAVTFSPDLGPVPH 720
A ++ EE + GP P +GEG +G T RPK P PVP
Sbjct: 837 PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP- 895
Query: 721 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLA--------------PPEAPGSAPP 766
GL ++N S + R+ + L Q LLA P PG +PP
Sbjct: 896 PGL-DFNLTESD-TVKRRPKCREREPL---QTALLAFGVASATPGPAAPLPSPTPGESPP 950
Query: 767 PAAWVIPGPTTGPKAASPSPARRVPATRR--SPGPGPS-QSPRSPKHTRPAELRLAPLTR 823
++ P P++ P P+P PA + P PGP +S + + E AP
Sbjct: 951 ASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1010
Query: 824 VLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAA 883
+ P +P V V + LA P P P + P
Sbjct: 1011 LKVPGAGT---------APKPVSV---ACTQLAFSGPKLAPRLGP-------RPVPPPRP 1051
Query: 884 EDEGDGSPAGAEDSLEEEASS 904
E G P A+ LE+ +SS
Sbjct: 1052 ESTGTVGPGQAQQRLEQTSSS 1072
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 58.5 bits (140), Expect = 4e-08
Identities = 105/433 (24%), Positives = 147/433 (33%), Gaps = 88/433 (20%)
Query: 607 EAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQ 666
E G G T A P L+ + SELS L+ + + + ++ +G +
Sbjct: 652 ENGEGPAT---AGPRLLTFQGSELSPELQAAMAGGGPEPLPLPPARSPSQESIGARS--- 705
Query: 667 VQPREASGEAEAEAEEADSG--PVPGGERPAGEGQGEPTSRPKAVTFSPDLGPVPHEGLG 724
SG ++ + SG P P ER EG P PK + P GP P+ +
Sbjct: 706 ----RGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP---PKLCSSLPGQGPPPYVFMY 758
Query: 725 EYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAPGSAPPPAAWVIPGPTTGPKAASP 784
P +P PPP A GP A P
Sbjct: 759 PQGS-----------------------------PSSPAPGPPPGAPWAFSYLAGPPATPP 789
Query: 785 SPARRVPATRRSPGPGPSQSPRSPKHTRPAELRL---APLTR------------VLTP-- 827
P R + PGP++ + P L A LTR +TP
Sbjct: 790 DPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGRSALVRTSPSVTPTP 849
Query: 828 ----PHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPP---EEPAARPGLIEIPLGSLAD 880
P R+ P P + SS+ PP E P + G +L++
Sbjct: 850 ARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSE 909
Query: 881 PAAEDEGDGSPAGA---EDSLEEEASSEGEP----RVGLGFFYKDEDKPEDEMAQKRASL 933
PA E G PA A D+ EEE EG P G G + +E + K A
Sbjct: 910 PAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP 969
Query: 934 LERQQ----------RRAEEARRRKQWQEVEKEQRREEAARLAQEEAPGPA-PLVSAVPM 982
R+ ++ +RR + +E E Q A +A PGPA PL S P
Sbjct: 970 PPRETPVPPGLDFNLTESDTVKRRPKCREREPLQTALLAFGVASA-TPGPAAPLPSPTPG 1028
Query: 983 ATPAPAARAPAEE 995
+P PA+ P E
Sbjct: 1029 ESP-PASSLPQPE 1040
Score = 57.4 bits (137), Expect = 9e-08
Identities = 120/479 (25%), Positives = 163/479 (34%), Gaps = 68/479 (14%)
Query: 346 PDFVQVKDLPDGHAASPRGTEASPPQNNSGSSSPVFTFRHPLLSSGGPQSPLRGSTGSLK 405
P Q ++LP+G P+ + P G P + F +P G P SP + G
Sbjct: 724 PSPPQERNLPEGTERPPKLCSSLP-----GQGPPPYVFMYP---QGSPSSP---APGPPP 772
Query: 406 SSPSMSHMEALGKAWNRQLSRPLSQAVSFSTPFGLDSDVDVVMGDPV--LLRSVSSDSLG 463
+P A A RP ++ S S P + D + PV L S ++ +
Sbjct: 773 GAPWAFSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRR 832
Query: 464 PPRPAPARTPTQPPPEP--GDLPTIEEALQIIHSAEPRLLPDGAADGSFYLHSPEGPSKP 521
P R A RT P P G + AL+ P P + S SPE P P
Sbjct: 833 PGRSALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSG--PSPEPP--P 888
Query: 522 SLASPYLPEGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASS 581
SP EG + P R P P P P+ + P P EG+P + SS
Sbjct: 889 LDESPGPKEGATGPRR-RTLSEPAGPSEPPGPPAPAGPASDTEEEEPGP-EGTPPSRGSS 946
Query: 582 PAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPAPPEALSSEMSELSARLEEKRRAI 641
FAE +K + P TP PP + + + K R
Sbjct: 947 GEGL-------PFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRER 999
Query: 642 EAQKRRIEAIFAKHRQRLGKSAFLQVQPREASGEAEAEAEEADSGPVPGGERPAGEGQGE 701
E + + A F G +A L P G E+ A S P P E + QG
Sbjct: 1000 EPLQTALLA-FGVASATPGPAAPL---PSPTPG----ESPPASSLPQP--EPSSLPAQGV 1049
Query: 702 PTSRPKAVTFSPDLGPVPHEGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLAPPEAP 761
PT + P + P P GL S+A S + + PP AP
Sbjct: 1050 PTPLAPSPAMQPPVPPCPGPGLE---------SSAASRWNGETE-----------PPAAP 1089
Query: 762 GSAPPPAAWVIPGPTTGPKAASPSPARRV-----PATRRSPGPGPSQSPRSPKHTRPAE 815
A +PG T PK S + + A R P P P P S P +
Sbjct: 1090 A-----ALLKVPGAGTAPKPVSVACTQLAFSGPKLAPRLGPRPVPPPRPESTGTVGPGQ 1143
Score = 56.2 bits (134), Expect = 2e-07
Identities = 120/501 (23%), Positives = 171/501 (34%), Gaps = 91/501 (18%)
Query: 455 RSVSSDSLGPPRPAPARTPTQPPPEP--GDLPTIEEALQIIHSAEPRLLPDGAADGSFYL 512
RS S +S+G + QP P+P GD +E R LP+G
Sbjct: 694 RSPSQESIGARSRGSGHSQEQPAPQPSGGDPSPPQE----------RNLPEGTERPPKLC 743
Query: 513 HSPEGPSKPSLASPYLPEGTSKPLSDRPTKAP---VYMPHPET--PSKPSPCLVGEASKP 567
S G P Y S P P AP Y+ P P P P +
Sbjct: 744 SSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPPDPPRPKRRSHSLSR 803
Query: 568 PAPSEGSPKAVASSPAATNSEVKMTSFAERKKQLVKAEAEAGAGSPTSTPA--------- 618
P P+EG + A P + + S+A ++ ++ + S T TPA
Sbjct: 804 PGPTEGDAEGEAEGPVGST----LGSYATLTRRPGRSALVRTSPSVTPTPARGTPRSQSF 859
Query: 619 --------PPEALSSEMSELSARLEEKRRAIEAQKRRIEAIFAKHRQRLGKSAFLQVQP- 669
PP +S +S E E+ + E R+ L + A P
Sbjct: 860 ALRARRKGPPPPPPKRLSSVSGPSPEPPPLDESPGPK-EGATGPRRRTLSEPAGPSEPPG 918
Query: 670 REASGEAEAEAEEADSGP--VPGGERPAGEG-----QGEPT--SRPKAVTFSPDLGPVPH 720
A ++ EE + GP P +GEG +G T RPK P PVP
Sbjct: 919 PPAPAGPASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVP- 977
Query: 721 EGLGEYNRAVSKLSAALSSLQRDMQRLTDQQQRLLA--------------PPEAPGSAPP 766
GL ++N S + R+ + L Q LLA P PG +PP
Sbjct: 978 PGL-DFNLTESD-TVKRRPKCREREPL---QTALLAFGVASATPGPAAPLPSPTPGESPP 1032
Query: 767 PAAWVIPGPTTGPKAASPSPARRVPATRR--SPGPGPS-QSPRSPKHTRPAELRLAPLTR 823
++ P P++ P P+P PA + P PGP +S + + E AP
Sbjct: 1033 ASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLESSAASRWNGETEPPAAPAAL 1092
Query: 824 VLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARPGLIEIPLGSLADPAA 883
+ P +P V V + LA P P P + P
Sbjct: 1093 LKVPGAGT---------APKPVSV---ACTQLAFSGPKLAPRLGP-------RPVPPPRP 1133
Query: 884 EDEGDGSPAGAEDSLEEEASS 904
E G P A+ LE+ +SS
Sbjct: 1134 ESTGTVGPGQAQQRLEQTSSS 1154
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 58.5 bits (140), Expect = 4e-08
Identities = 90/352 (25%), Positives = 116/352 (32%), Gaps = 53/352 (15%)
Query: 716 GPVPHEGLGEYN-----RAVSKLSAALSSLQRDMQRLTDQQQRLL--APPEAPGSAPPPA 768
GP P E RAV ++S S R+ R+ ++ APP AP AP A
Sbjct: 63 GPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRGAPAAA 122
Query: 769 AWVIPGPTTGP-------KAASPSPARRVPATRRSPGPGPSQSPRSPKHTRPAELRLAPL 821
A P PT P AA+P+ A R A + P P + P+ R A L P
Sbjct: 123 AAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP 182
Query: 822 T-------------RVLTPPHDVDSLPHLRKFSPSQVPVQTRSSILLAEETPPEEPAARP 868
R PP P L P Q + + PPE A R
Sbjct: 183 APAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRA 242
Query: 869 GLIEIPLGSLADPAAEDEGDGSPAG------AEDSLEEEASSEGE-PRVGLGFFYKDEDK 921
G P+ SL + G G G + LEEEA++ G R LG
Sbjct: 243 GGAARPV-SLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGD 301
Query: 922 PEDEMAQKRASLLERQQRRAEEARRRKQWQEVEKEQRREEAARLAQEEAP---------- 971
++ R +R EE K+ +E + E EE E P
Sbjct: 302 RPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEEDDVSEGSEVPESDRPAGAQH 361
Query: 972 -------GPAPLVSAVPMATPAPAARAPAEEEVGPRKGDFTRQEYERRAQLK 1016
GP V TP +E GP G TRQ + A K
Sbjct: 362 HQLNGERGPQSAKERVKEWTPC-GPHQGQDEGRGPAPGSGTRQVFSMAAMNK 412
Score = 33.1 bits (74), Expect = 1.7
Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 3/91 (3%)
Query: 530 EGTSKPLSDRPTKAPVYMPHPETPSKPSPCLVGEASKPPAPSEGSPKAVASSPAATNSEV 589
EG+ P SDRP A + + E + + V E + P P +G + +P + +V
Sbjct: 346 EGSEVPESDRPAGAQHHQLNGERGPQSAKERVKEWT-PCGPHQGQDEGRGPAPGSGTRQV 404
Query: 590 KMTSFAERKKQLVKAEAEAGAGSPTSTPAPP 620
S A K+ A G SP+ P PP
Sbjct: 405 --FSMAAMNKEGGTASVATGPDSPSPVPLPP 433
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,381,416
Number of Sequences: 37866
Number of extensions: 3909350
Number of successful extensions: 39734
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 293
Number of HSP's successfully gapped in prelim test: 1778
Number of HSP's that attempted gapping in prelim test: 22816
Number of HSP's gapped (non-prelim): 13651
length of query: 1276
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1162
effective length of database: 13,930,794
effective search space: 16187582628
effective search space used: 16187582628
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.