Search of human proteins with 28372503

Search of human proteins with 28372503

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28372503 keratin 72 isoform 1 [Homo sapiens]
         (511 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       990   0.0  
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      990   0.0  
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      823   0.0  
gi|28173564 keratin 73 [Homo sapiens]                                 701   0.0  
gi|15618995 keratin 71 [Homo sapiens]                                 701   0.0  
gi|148612803 keratin 6 irs4 [Homo sapiens]                            682   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  567   e-162
gi|155969697 keratin 6C [Homo sapiens]                                566   e-161
gi|119703753 keratin 6B [Homo sapiens]                                566   e-161
gi|109255249 keratin 4 [Homo sapiens]                                 564   e-161
gi|153791158 keratin 75 [Homo sapiens]                                548   e-156
gi|119395754 keratin 5 [Homo sapiens]                                 547   e-156
gi|109148552 keratin 3 [Homo sapiens]                                 538   e-153
gi|153791670 keratin 76 [Homo sapiens]                                535   e-152
gi|47132620 keratin 2 [Homo sapiens]                                  525   e-149
gi|119395750 keratin 1 [Homo sapiens]                                 524   e-149
gi|32567786 keratin 6L [Homo sapiens]                                 518   e-147
gi|194018511 keratin 77 [Homo sapiens]                                506   e-143
gi|67782365 keratin 7 [Homo sapiens]                                  466   e-131
gi|4504919 keratin 8 [Homo sapiens]                                   463   e-130
gi|89357932 keratin 5b [Homo sapiens]                                 459   e-129
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    431   e-121
gi|27477127 keratin 82 [Homo sapiens]                                 407   e-114
gi|4504935 keratin 85 [Homo sapiens]                                  406   e-113
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   392   e-109
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   391   e-109
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   391   e-109
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   391   e-109
gi|14318422 keratin 86 [Homo sapiens]                                 391   e-109
gi|169790841 keratin 83 [Homo sapiens]                                387   e-107

>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  990 bits (2560), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60
           MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60

Query: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120
           SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR
Sbjct: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120

Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180
           VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI
Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180

Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240
           SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY
Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240

Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300
           MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR
Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300

Query: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360
           AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV
Sbjct: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360

Query: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420
           KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL
Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420

Query: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480
           DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA
Sbjct: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480

Query: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
           DVKTKGSCGSELKDPLAKTSGSSCATKKASR
Sbjct: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  990 bits (2560), Expect = 0.0
 Identities = 511/511 (100%), Positives = 511/511 (100%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60
           MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60

Query: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120
           SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR
Sbjct: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120

Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180
           VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI
Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180

Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240
           SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY
Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240

Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300
           MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR
Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300

Query: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360
           AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV
Sbjct: 301 AQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNV 360

Query: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420
           KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL
Sbjct: 361 KKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLAL 420

Query: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480
           DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA
Sbjct: 421 DMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYKTAAA 480

Query: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
           DVKTKGSCGSELKDPLAKTSGSSCATKKASR
Sbjct: 481 DVKTKGSCGSELKDPLAKTSGSSCATKKASR 511


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  823 bits (2125), Expect = 0.0
 Identities = 440/515 (85%), Positives = 449/515 (87%), Gaps = 50/515 (9%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60
           MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL
Sbjct: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLAL 60

Query: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120
           SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR
Sbjct: 61  SAAARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQR 120

Query: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180
           VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI
Sbjct: 121 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYI 180

Query: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240
           SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY
Sbjct: 181 SNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAY 240

Query: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300
           MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR
Sbjct: 241 MNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVR 300

Query: 301 AQYEEIALKSKAEAETLYQTKIQELQVT---AGQHGD-DLKLTKAEISELNRLIQRIRSE 356
           AQYEEIALKSKAEAETLYQTK  +L+     A Q GD  LK  +A++ EL   + + + E
Sbjct: 301 AQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE 360

Query: 357 IGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSL 416
           +                                              ARMLREYQELVSL
Sbjct: 361 L----------------------------------------------ARMLREYQELVSL 374

Query: 417 KLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYK 476
           KLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYK
Sbjct: 375 KLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGASSSYSYK 434

Query: 477 TAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
           TAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR
Sbjct: 435 TAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 469


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  701 bits (1809), Expect = 0.0
 Identities = 380/543 (69%), Positives = 426/543 (78%), Gaps = 35/543 (6%)

Query: 1   MSRQLTHFP-RGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58
           MSRQ T+      + GFSGCSAVLSGG   SS+S+RA  KG S  F S+SL  LGG+RS+
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGG---SSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57

Query: 59  ALSAAARRGG--------GRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPL 110
           + + A+  G         GR  GF G+ FGS  LG  CPS+CPPGGI QVT+NKSLLAPL
Sbjct: 58  SFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPL 117

Query: 111 NVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRK 170
           NVE+DPEIQ+VRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ 
Sbjct: 118 NVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 177

Query: 171 NLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFV 230
           NLEPI EGYISNL+KQLE LSGD VRLDSELR+++++VEDYKKRYE EIN+RT AENEFV
Sbjct: 178 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFV 237

Query: 231 VLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDL 290
           VLKKDVDAAY +KVELQAKVD+L  EIKFFKCLYEGE  QIQSHISDTSI+LSMDNNR+L
Sbjct: 238 VLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNL 297

Query: 291 DLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLI 350
           DLDSIIAEVRAQYEEIA KSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLI
Sbjct: 298 DLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLI 357

Query: 351 QRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREY 410
           QR+RSEI +VKKQCA+LETAIADAEQRGDCALKDARAKLDELEGAL QAKEELARMLREY
Sbjct: 358 QRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREY 417

Query: 411 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGAS 470
           QEL+S+KL+LD+EIATYRKLLE EECRMSGEY NSVSISVI+S+ AG  G G   GF  +
Sbjct: 418 QELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNA 477

Query: 471 SSYSYKTAA----------------------ADVKTKGSCGSELKDPLAKTSGSSCATKK 508
            +Y Y  ++                       + +T+    SE +D   KT   S  TKK
Sbjct: 478 GTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKK 537

Query: 509 ASR 511
             R
Sbjct: 538 TMR 540


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  701 bits (1808), Expect = 0.0
 Identities = 386/528 (73%), Positives = 432/528 (81%), Gaps = 22/528 (4%)

Query: 1   MSRQLT-HFPRGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58
           MSRQ T       + GFSGCSAVLSGG   SS+SFRA  KG S  FGS+SL  LGG RSL
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGG---SSSSFRAGSKGLSGGFGSRSLYSLGGVRSL 57

Query: 59  ALSAAARRGGG------RLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNV 112
            +++ + + GG      R  GF G+ FGS  LGP CP+VCPPGGI QVTVN+SLLAPLNV
Sbjct: 58  NVASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNV 117

Query: 113 EMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNL 172
           E+DPEIQ+VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ NL
Sbjct: 118 ELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNL 177

Query: 173 EPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVL 232
           EPI EGYISNL+KQLE LSGD VRLDSELRN++D+VEDYKKRYE EIN+RTAAENEFV+L
Sbjct: 178 EPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLL 237

Query: 233 KKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDL 292
           KKDVDAAY NKVELQAKV+S+  EIKFF+CL+E EITQIQSHISD S++LSMDNNR+LDL
Sbjct: 238 KKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDL 297

Query: 293 DSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQR 352
           DSII EVR QYEEIALKSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLIQR
Sbjct: 298 DSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQR 357

Query: 353 IRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQE 412
           IRSEI NVKKQ ++LETAIADAEQRGD ALKDARAKLDELEGALHQAKEELARMLREYQE
Sbjct: 358 IRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQE 417

Query: 413 LVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF-----SMGF 467
           L+SLKLALDMEIATYRKLLESEECRMSGE+P+ VSIS+ISST+ G+   GF     S G+
Sbjct: 418 LMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGGS-VYGFRPSMVSGGY 476

Query: 468 GASSSYSY----KTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
            A+SS            + +++GS  ++ KD L K S  S  +KK SR
Sbjct: 477 VANSSNCISGVCSVRGGEGRSRGS-ANDYKDTLGKGSSLSAPSKKTSR 523


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  682 bits (1761), Expect = 0.0
 Identities = 373/529 (70%), Positives = 418/529 (79%), Gaps = 18/529 (3%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGS-ASFGSKSLSCLGGSRSLA 59
           MSRQL     G++  FS  SAV+      S AS+ A  +G+ A FGS+SL  LGG+R ++
Sbjct: 1   MSRQLNIKSSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRIS 60

Query: 60  LSAA--------------ARRGGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKS 105
            + A              +  GGGR  GF G+ FGS  LGP C SVCPPGGI QVTVNKS
Sbjct: 61  FNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKS 120

Query: 106 LLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDL 165
           LLAPLNVE+DPEIQ+VRAQEREQIK LN+KFASFIDKVRFLEQQNQVLETKW LLQQLDL
Sbjct: 121 LLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDL 180

Query: 166 NNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAA 225
           NNC+KNLEPI EGYISNL+KQLE LSGD VRLDSELR+M+DLVEDYKKRYEVEINRRT A
Sbjct: 181 NNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTA 240

Query: 226 ENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMD 285
           ENEFVVLKKD DAAY  KVELQAKVDSL  EIKF KCLY+ EI QIQ+H S+TS++LSMD
Sbjct: 241 ENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMD 300

Query: 286 NNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISE 345
           NNRDLDLDSIIAEVR  YEEIALKSKAEAE LYQTKIQELQ+ A +HGDDLK T++E+ E
Sbjct: 301 NNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVE 360

Query: 346 LNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELAR 405
           LNRLIQRIR EIGNVKKQ A LETAIADAEQRGD ALKDA+AKLDELEGALHQAKEELAR
Sbjct: 361 LNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELAR 420

Query: 406 MLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAG---AGGAG 462
           MLREYQEL+SLKLALDMEIATYRKLLE EECRMSGE P+SVSISVISS++        AG
Sbjct: 421 MLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAG 480

Query: 463 FSMGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKKASR 511
             +G  A +  S  T +   KT  + G +LKD   K++ +S   +KA+R
Sbjct: 481 VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPASIPARKATR 529


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  567 bits (1462), Expect = e-162
 Identities = 314/538 (58%), Positives = 385/538 (71%), Gaps = 38/538 (7%)

Query: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 19  SANSARLPGVSRSGFSSVSVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73

Query: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132

Query: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLE
Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLE 192

Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELR MQDLVED+K +
Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNK 252

Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312

Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD 334
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK +ELQVTAG+HGD
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372

Query: 335 DLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEG 394
           DL+ TK EI+E+NR+IQR+RSEI +VKKQCA+L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432

Query: 395 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 454
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V+ISV+ ST
Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492

Query: 455 ----NAGAGGAGFSMGFGASSSYSYKTA-AADVKTKGSCGSELKDPLAKTSGSSCATK 507
                 GA G G  +G G  SSYSY +          S G  +   L+   G S   K
Sbjct: 493 VSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAIGGGLSSVGGGSSTIK 550


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  566 bits (1458), Expect = e-161
 Identities = 307/505 (60%), Positives = 375/505 (74%), Gaps = 37/505 (7%)

Query: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 19  SANSARLPGVSRSGFSSISVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73

Query: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132

Query: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VL+
Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLD 192

Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED K +
Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNK 252

Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312

Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD 334
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK +ELQVTAG+HGD
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGD 372

Query: 335 DLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEG 394
           DL+ TK EI+E+NR+IQR+RSEI +VKKQCA L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLED 432

Query: 395 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 454
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V++SV+ ST
Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQST 492

Query: 455 ----NAGAGGAGFSMGFGASSSYSY 475
                 GA G G  +G G  SSYSY
Sbjct: 493 ISSGYGGASGVGSGLGLGGGSSYSY 517


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  566 bits (1458), Expect = e-161
 Identities = 307/505 (60%), Positives = 376/505 (74%), Gaps = 37/505 (7%)

Query: 2   SRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALS 61
           S      P   R GFS  S   S G G    +      G A FGS+SL  LGGS+ +++ 
Sbjct: 19  SANSARLPGVSRSGFSSISVSRSRGSGGLGGAC-----GGAGFGSRSLYGLGGSKRISIG 73

Query: 62  AAA--------RRGGGRLG-GFVGTAFG-------------SAGL-----GPKCPSVCPP 94
             +         R GG  G G  G+ FG              AGL     GP  P VCPP
Sbjct: 74  GGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFP-VCPP 132

Query: 95  GGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLE 154
           GGI +VTVN+SLL PLN+++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VL+
Sbjct: 133 GGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLD 192

Query: 155 TKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKR 214
           TKW LLQ+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED K +
Sbjct: 193 TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNK 252

Query: 215 YEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSH 274
           YE EIN+RTAAENEFV LKKDVDAAYMNKVELQAK D+LTDEI F + LY+ E++Q+Q+H
Sbjct: 253 YEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTH 312

Query: 275 ISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGD 334
           ISDTS+VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+AEAE+ YQTK +ELQ+TAG+HGD
Sbjct: 313 ISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGD 372

Query: 335 DLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEG 394
           DL+ TK EI+E+NR+IQR+RSEI +VKKQCA+L+ AIADAEQRG+ ALKDA+ KL+ LE 
Sbjct: 373 DLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLED 432

Query: 395 ALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISST 454
           AL +AK++LAR+L+EYQEL+++KLALD+EIATYRKLLE EECR++GE    V+ISV+ ST
Sbjct: 433 ALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQST 492

Query: 455 ----NAGAGGAGFSMGFGASSSYSY 475
                 GA G G  +G G  SSYSY
Sbjct: 493 VSSGYGGASGVGSGLGLGGGSSYSY 517


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  564 bits (1453), Expect = e-161
 Identities = 307/482 (63%), Positives = 370/482 (76%), Gaps = 20/482 (4%)

Query: 10  RGERLGFSGCSAVLSGG----IGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAAR 65
           RG   GFS  SA++ GG      S S S  A    S  FGS+SL  L G++S+++S A  
Sbjct: 83  RGGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGS 142

Query: 66  R-----------GGGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEM 114
           R           G G  GG  G +F   G GP  P VCP GGI +VT+N+SLL PL+VE+
Sbjct: 143 RQGACFGGAGGFGTGGFGGGFGGSFSGKG-GPGFP-VCPAGGIQEVTINQSLLTPLHVEI 200

Query: 115 DPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEP 174
           DPEIQ+VR +EREQIK LNNKFASFIDKV+FLEQQN+VLETKWNLLQQ       KNLEP
Sbjct: 201 DPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEP 260

Query: 175 IYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKK 234
           ++E Y+S L+KQL+ L  D  RL SEL+ MQD VED+K +YE EIN+RTAAEN+FVVLKK
Sbjct: 261 LFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKK 320

Query: 235 DVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDS 294
           DVDAAY+NKVEL+AKVDSL DEI F K LY+ E++Q+Q+H+SDTS+VLSMDNNR+LDLDS
Sbjct: 321 DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDS 380

Query: 295 IIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIR 354
           IIAEVRAQYEEIA +SKAEAE LYQTK+Q+LQ++  QHGD+LK TK+EI+ELNR+IQR+R
Sbjct: 381 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLR 440

Query: 355 SEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELV 414
           +EI N+KKQC  L+ ++ADAEQRG+ ALKDA +K  ELE AL QAKEELARMLREYQEL+
Sbjct: 441 AEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELM 500

Query: 415 SLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS---STNAGAGGAGFSMGFGASS 471
           S+KLALD+EIATYRKLLE EE RMSGE  ++VSISV+S   ST   +GG G   GFG SS
Sbjct: 501 SVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS 560

Query: 472 SY 473
            +
Sbjct: 561 GF 562


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  548 bits (1413), Expect = e-156
 Identities = 308/538 (57%), Positives = 395/538 (73%), Gaps = 31/538 (5%)

Query: 1   MSRQLT-HFPRGERLGFSGCSAVL--SGGIGSSSASFRARVKGS----------ASFGSK 47
           MSRQ +  F  G R GFS  SA+   +G    SS S      GS          ASFGS+
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 48  SLSCLGGSRSLALS---AAARRG-GGRLGGFVG--TAFGSAG------LGPKCPSVCPPG 95
           SL  LGG++ ++++   ++ R G GGR     G  + FG  G       GP  P VCPPG
Sbjct: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFP-VCPPG 119

Query: 96  GIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLET 155
           GI +VTVN+SLL PL++++DP IQRVRA+EREQIK LNNKFASFIDKVRFLEQQN+VLET
Sbjct: 120 GIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLET 179

Query: 156 KWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRY 215
           KW LLQ+      R+NLEP+++ Y S L++QLE ++ +  RL++ELRNMQD+VED+K RY
Sbjct: 180 KWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRY 239

Query: 216 EVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHI 275
           E EIN+RTAAENEFV LKKDVDAAYMNKVEL+AKV SL +EI F   +++ E++Q+Q+ +
Sbjct: 240 EDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQV 299

Query: 276 SDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDD 335
            DTS+VLSMDNNR+LDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK +ELQVTAG+HGDD
Sbjct: 300 GDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDD 359

Query: 336 LKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGA 395
           L+ TK EISE+NR+IQR+R+EI +VKKQC+ L+TAIADAEQRG+ ALKDARAKL +LE A
Sbjct: 360 LRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEA 419

Query: 396 LHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTN 455
           L +AK+++AR+LREYQEL+++KLALD+EIATYRKLLE EECR+SGE  + V+ISV++ST 
Sbjct: 420 LQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTL 479

Query: 456 AGAGGAGFS-----MGFGASSSYSYKTAAADVKTKGSCGSELKDPLAKTSGSSCATKK 508
           +   G+G S     +G G  S YS+ T+       G  GS       +  G S ++ K
Sbjct: 480 SSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  547 bits (1410), Expect = e-156
 Identities = 295/490 (60%), Positives = 365/490 (74%), Gaps = 31/490 (6%)

Query: 9   PRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARR-- 66
           P   R  F+  S    GG G       A   G   +GS+SL  LGGS+ +++S +     
Sbjct: 25  PSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFR 84

Query: 67  -----------------------GGGRLGGFV---GTAFGSAGLGPKCPSVCPPGGIPQV 100
                                  GGG  GGF    G  FG    GP  P VCPPGGI +V
Sbjct: 85  NRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFP-VCPPGGIQEV 143

Query: 101 TVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL 160
           TVN+SLL PLN+++DP IQRVR +EREQIK LNNKFASFIDKVRFLEQQN+VL+TKW LL
Sbjct: 144 TVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLL 203

Query: 161 QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEIN 220
           Q+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED+K +YE EIN
Sbjct: 204 QEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEIN 263

Query: 221 RRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSI 280
           +RT AENEFV+LKKDVDAAYMNKVEL+AKVD+L DEI F K  ++ E++Q+Q+H+SDTS+
Sbjct: 264 KRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSV 323

Query: 281 VLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTK 340
           VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+ EAE+ YQTK +ELQ TAG+HGDDL+ TK
Sbjct: 324 VLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTK 383

Query: 341 AEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAK 400
            EISE+NR+IQR+R+EI NVKKQCA+L+ AIADAEQRG+ ALKDAR KL ELE AL +AK
Sbjct: 384 HEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAK 443

Query: 401 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI-SSTNAGAG 459
           +++AR+LREYQEL++ KLALD+EIATYRKLLE EECR+SGE    V+ISV+ SS ++G G
Sbjct: 444 QDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYG 503

Query: 460 -GAGFSMGFG 468
            G+G+  G G
Sbjct: 504 SGSGYGGGLG 513


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  538 bits (1387), Expect = e-153
 Identities = 308/546 (56%), Positives = 378/546 (69%), Gaps = 81/546 (14%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASFGSKSL 49
           MSRQ +    G   GFSG SAV+SG           G G  +  FR+   G+  FGS+SL
Sbjct: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRS---GAGGFGSRSL 57

Query: 50  SCLGGSRSLALSAAA---RRGG-------------------------------------- 68
             LGG++S+++S AA   R GG                                      
Sbjct: 58  YNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGG 117

Query: 69  --------GRLGGFVGTAF--------GSAGLGPKCPSVCP--------PGGIPQVTVNK 104
                   G  GGF G           GS G G       P        PGGI +VT+N+
Sbjct: 118 GFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQ 177

Query: 105 SLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLD 164
           SLL PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWNLLQQ  
Sbjct: 178 SLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQG 237

Query: 165 LNNCR--KNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRR 222
            ++     NLEP++E +I+ L+  L+ + G+  RLDSEL+NM+DLVED+KK+YE EIN+R
Sbjct: 238 TSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKR 297

Query: 223 TAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVL 282
           TAAENEFV LKKDVD+AYMNKVELQAKVD+L DEI F + LY+ E++Q+QSHISDTS+VL
Sbjct: 298 TAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVL 357

Query: 283 SMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAE 342
           SMDNNR LDLDSIIAEVRAQYE+IA +SKAEAE LYQTK+ ELQ TAG+HGDDL+ TK+E
Sbjct: 358 SMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSE 417

Query: 343 ISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEE 402
           I ELNR+IQR+R+EI  VKKQ A+L+TAIA+AEQ G+ ALKDA AKL EL+ AL QAK++
Sbjct: 418 IIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDD 477

Query: 403 LARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAG 462
           LAR+LR+YQEL+++KLALD+EIATYRKLLE EE RMSGE P++VSISV+SS+   A   G
Sbjct: 478 LARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGG 537

Query: 463 FSMGFG 468
           +  G+G
Sbjct: 538 YGGGYG 543


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  535 bits (1379), Expect = e-152
 Identities = 312/540 (57%), Positives = 382/540 (70%), Gaps = 67/540 (12%)

Query: 11  GERLGFSGCSAVLSG-----------GIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA 59
           G   GFSG SAV+SG           G G  +  FR+   G+ SFGS+SL  LG ++S++
Sbjct: 12  GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRS---GAGSFGSRSLYNLGSNKSIS 68

Query: 60  LSAAARR------GGGRL-----------------GGF-----VGTAFGSAGL-----GP 86
           +S AA        GGGR                  GGF     VG+ FG AG      G 
Sbjct: 69  ISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGF 128

Query: 87  KCPSVCP----------------PGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130
             P V                  PGGI +V VN+SLL PLNVE+DP+I +V+AQEREQIK
Sbjct: 129 GGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIK 188

Query: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190
            LNNKFASFIDKVRFLEQQN+VLETKW LLQQ    +   +LEP +E YIS L KQL+ L
Sbjct: 189 TLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSL 248

Query: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250
            G+   L+ EL++MQDLVED+KK+YE EIN+RTAAENEFV LKKDVDAA+MNKVELQAKV
Sbjct: 249 LGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKV 308

Query: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310
           DSLTDE+ F + LYE E++Q+QSH SDTS+VLSMDNNR LDL SIIAEVRAQYEEIA +S
Sbjct: 309 DSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRS 368

Query: 311 KAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETA 370
           K+EAE LYQTK+ ELQ TAG+HGDDL+ TK+EI ELNR+IQR+R+EI NVKKQ A+L+TA
Sbjct: 369 KSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTA 428

Query: 371 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 430
           IA+AEQRG+ ALKDA AKL +L+ AL +AK++LAR+LR+YQEL+++KLALD+EIATYRKL
Sbjct: 429 IAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKL 488

Query: 431 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMG-FG---ASSSYSYKTAAADVKTKG 486
           LE EECRMSGE  ++V ISV+S+  + +G +G S G FG    S S  YK  ++   + G
Sbjct: 489 LEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSG 548



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 31/89 (34%), Positives = 39/89 (43%), Gaps = 3/89 (3%)

Query: 10  RGERLGFSGC-SAVLSGGIGSSSASFRARVKGSAS-FGSKSLSCLGGSRSLALSAAARRG 67
           RG   G SG  S    GG  SSS+S      GS S +G  S    GG R  + S  +   
Sbjct: 523 RGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGG-RGSSGSYQSSSS 581

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGG 96
           G RLGG    +   +G+G    S+   GG
Sbjct: 582 GSRLGGAGSISVSHSGMGSSSGSIQTSGG 610


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  525 bits (1353), Expect = e-149
 Identities = 298/537 (55%), Positives = 373/537 (69%), Gaps = 66/537 (12%)

Query: 15  GFSGCSAVLSGGIGSSSASFRARVK--------GSASFGSKSLSCLGGSRSLALSAAARR 66
           GFS  SAV+SGG   S++SF    +        G   FGS+SL  LGG++S+++S A   
Sbjct: 21  GFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGG 80

Query: 67  GG--------------------------------------GRLGGF-----VGTAFGSAG 83
           GG                                      GR GGF     VG   G  G
Sbjct: 81  GGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGG 140

Query: 84  LGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
            GP       PGGI +V+VN+SLL PLNV++DPEIQ V+AQEREQIK LNNKFASFIDKV
Sbjct: 141 FGPGGY----PGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKV 196

Query: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
           RFLEQQNQVL+TKW LLQQ+++     NLEPI++GYI +L++ L+ L+ +    +SEL N
Sbjct: 197 RFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNN 256

Query: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
           MQDLVEDYKK+YE EIN+RTAAEN+FV LKKDVD AYM KVELQ+KVD L  EI+F K L
Sbjct: 257 MQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVL 316

Query: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
           Y+ EI+QI   ++DT+++LSMDN+R+LDLDSIIAEV+AQYEEIA +SK EAE LY +K +
Sbjct: 317 YDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYE 376

Query: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
           ELQVT G+HGD LK  K EISELNR+IQR++ EI +VKKQC +++ AIADAEQRG+ ALK
Sbjct: 377 ELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALK 436

Query: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
           DAR KL++LE AL QAKE+LAR+LR+YQEL+++KLALD+EIATYRKLLE EECRMSG+  
Sbjct: 437 DARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLS 496

Query: 444 NSVSISVISSTNA----------GAGGAGFSMGFGASS-SYSYKTAAADVKTKGSCG 489
           ++V++SV SST +          G+GG G S G G SS S SY +      ++G  G
Sbjct: 497 SNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSG 553



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 25/75 (33%), Positives = 29/75 (38%), Gaps = 3/75 (4%)

Query: 11  GERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGR 70
           G R G  G  ++  GG GS   S      G    GSK  S  GG         +  GG R
Sbjct: 547 GSRGGSGGGGSISGGGYGSGGGSGGRYGSGG---GSKGGSISGGGYGSGGGKHSSGGGSR 603

Query: 71  LGGFVGTAFGSAGLG 85
            G   G  +GS G G
Sbjct: 604 GGSSSGGGYGSGGGG 618


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  524 bits (1350), Expect = e-149
 Identities = 289/523 (55%), Positives = 368/523 (70%), Gaps = 62/523 (11%)

Query: 16  FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRL---- 71
           FS C     GG GS  A           FGS+SL  LGGS+S+++S A  RGGGR     
Sbjct: 46  FSSCG----GGGGSFGAG--------GGFGSRSLVNLGGSKSISISVA--RGGGRGSGFG 91

Query: 72  -----------------------------------GGFVGTAFGSAGLGPKCPSVCPPGG 96
                                              GGF G  FG  G G     VCPPGG
Sbjct: 92  GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151

Query: 97  IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETK 156
           I +VT+N+SLL PLNVE+DPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQNQVL+TK
Sbjct: 152 IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK 211

Query: 157 WNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216
           W LLQQ+D +    NLEP +E +I+NL+++++ L  D  RLDSEL+NMQD+VEDY+ +YE
Sbjct: 212 WELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYE 271

Query: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276
            EIN+RT AENEFV +KKDVD AYM KV+LQAK+D+L  EI F   LY+ E++Q+Q+ IS
Sbjct: 272 DEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 331

Query: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336
           +T+++LSMDNNR LDLDSIIAEV+AQYE+IA KSKAEAE+LYQ+K +ELQ+TAG+HGD +
Sbjct: 332 ETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSV 391

Query: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396
           + +K EISELNR+IQR+RSEI NVKKQ ++L+ +I+DAEQRG+ ALKDA+ KL++LE AL
Sbjct: 392 RNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDAL 451

Query: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISS--- 453
            QAKE+LAR+LR+YQEL++ KLALD+EIATYR LLE EE RMSGE   +VS+SV +S   
Sbjct: 452 QQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTT 511

Query: 454 ----TNAGAGGAGFSMGFGA--SSSYSYKTAAADVKTKGSCGS 490
                + G GG G+  G  +  S   SY +       +GS GS
Sbjct: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  518 bits (1335), Expect = e-147
 Identities = 291/494 (58%), Positives = 364/494 (73%), Gaps = 33/494 (6%)

Query: 1   MSRQLTHFPRGERLGFSGCSAVLSGGIGSSSASFRARVK---------------GSASFG 45
           +SRQ T+  +G   GFS  SA  SGG GS + +  + V                G+  FG
Sbjct: 5   VSRQ-TYSTKG---GFSSNSA--SGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFG 58

Query: 46  SKSLSCLGGSRSLALSAAARRGGGRLG------GFVGTAFGSAGLGPKC-PSVCPPGGIP 98
           S+SL  LGG +S+++S A   GG  LG      GF   AF   G G +     CPPGGI 
Sbjct: 59  SRSLYNLGGHKSISVSVA---GGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQ 115

Query: 99  QVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWN 158
           +VTVN+SLL PL+VE+DPEIQRVR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW 
Sbjct: 116 EVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWA 175

Query: 159 LLQQL--DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216
           LLQ+   +L   R NLEP++E Y+ +++  L+ L  +  RLDSELRN+QDLVED+K +YE
Sbjct: 176 LLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYE 235

Query: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276
            EIN+ TAAENEFVVLKKDVDAAYM +++L  KV +LT EI F + LYE E++Q+Q+H+S
Sbjct: 236 DEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVS 295

Query: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336
           +T++VLSMDNNR+LDLDSIIAEV+AQYE IA +S+AEAE  YQTK +ELQVTAG+HGD+L
Sbjct: 296 NTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNL 355

Query: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396
           + TK EI+EL R IQR++ E    KKQC  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL
Sbjct: 356 RDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVAL 415

Query: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA 456
           HQAKE+L R+LR+YQEL+++KLALD+EIATYRKLLESEE RMSGE P++VSISV  ++  
Sbjct: 416 HQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTT 475

Query: 457 GAGGAGFSMGFGAS 470
             GG   S G G S
Sbjct: 476 VCGGGAASFGGGIS 489


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  506 bits (1303), Expect = e-143
 Identities = 287/551 (52%), Positives = 377/551 (68%), Gaps = 47/551 (8%)

Query: 8   FPRGERLGFSGCSAVLSGGIGSSSASF---RARVKGSA------SFGSKSLSCLGGSRSL 58
           F    R  +S  S+  SGG   +  S    R R  G         FGS+SL  LGGSRS+
Sbjct: 11  FSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSI 70

Query: 59  ALSAAARR-------------GGGR--------LGGFVGTAFGSAGLGPKCPSV------ 91
           +++   R              GGGR         GGF G  FG AG G     +      
Sbjct: 71  SINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPY 130

Query: 92  CPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQ 151
           CPPGGI +VT+N+SLL PL++E+DPEIQR++ QEREQI  LNNKFASFIDKVRFLEQQNQ
Sbjct: 131 CPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQ 190

Query: 152 VLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDY 211
           VL+TKW LLQQ++ +    NLEP+ E YI +L++Q+++LS + +R ++E+R+MQD+VEDY
Sbjct: 191 VLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDY 250

Query: 212 KKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQI 271
           K +YE EIN+RT +EN+FVVLKKDVDAAY++KV+L+++VD+LT E+ F K L+  E++Q+
Sbjct: 251 KSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQV 310

Query: 272 QSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQ 331
           Q+HISDT+++LSMDNNR LDLDSII  VR QYE IA +SK EAE LYQTK QELQ+TAG+
Sbjct: 311 QTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGR 370

Query: 332 HGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDE 391
           HGDDLK +K EI+ELNR +QR+++EI NVKKQ   +++ I+DAE+RG+ AL+DA  KL +
Sbjct: 371 HGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQD 430

Query: 392 LEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI 451
           LE AL Q+KEELAR+LR+YQ ++ +KL+LD+EIATYR+LLE EE RMSGE  + VSISV 
Sbjct: 431 LEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQ 490

Query: 452 S---STNAGAGGAGF--SMGFGASS------SYSYKTAAADVKTKGSCGSELKDPLAKTS 500
           +   S N GAGG G   S G+G  S        SY+   A  ++ G  GS          
Sbjct: 491 NSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSGGGYGSGCGGGGGSYG 550

Query: 501 GSSCATKKASR 511
           GS  + + +SR
Sbjct: 551 GSGRSGRGSSR 561


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  466 bits (1199), Expect = e-131
 Identities = 258/439 (58%), Positives = 326/439 (74%), Gaps = 17/439 (3%)

Query: 55  SRSLALS---AAARRGGGRLGGFVGTAFGSAGLGPKCPSVC-------PPG-GIPQVTVN 103
           SRS A S   A  R    R GG   ++    GLG   P V        P G GI +VT+N
Sbjct: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSL--YGLGASRPRVAVRSAYGGPVGAGIREVTIN 69

Query: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163
           +SLLAPL ++ DP +QRVR +E EQIK LNNKFASFIDKVRFLEQQN++LETKW LLQ+ 
Sbjct: 70  QSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129

Query: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223
                 + L  I+E  I+ L+ QLE L  DG RL++ELR+MQD+VED+K +YE EIN RT
Sbjct: 130 KSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRT 188

Query: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283
           AAENEFVVLKKDVDAAYM+KVEL+AKVD+L DEI F + L E E+T++QS ISDTS+VLS
Sbjct: 189 AAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLS 248

Query: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEI 343
           MDN+R LDLD IIAEV+AQYEE+A  S+AEAE  YQTK + LQ  AG+HGDDL+ T+ EI
Sbjct: 249 MDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEI 308

Query: 344 SELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEEL 403
           SE+NR IQR+++EI N+K Q A LE AIA+AE+RG+ ALKDARAK +ELE AL + K+++
Sbjct: 309 SEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDM 368

Query: 404 ARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF 463
           AR LREYQEL+S+KLALD+EIATYRKLLE EE R++G+   +V+ISV++ST   + G G 
Sbjct: 369 ARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGI 428

Query: 464 SMGFG---ASSSYSYKTAA 479
            +  G    S++ S+ ++A
Sbjct: 429 GLTLGGTMGSNALSFSSSA 447


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  463 bits (1192), Expect = e-130
 Identities = 253/456 (55%), Positives = 332/456 (72%), Gaps = 16/456 (3%)

Query: 33  SFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGFVGTAFGSAGLGPKCPSVC 92
           S++    G  +F S+S +   GSR ++ S+ +R G     G +G  +G A          
Sbjct: 9   SYKVSTSGPRAFSSRSYTSGPGSR-ISSSSFSRVGSSNFRGGLGGGYGGAS--------- 58

Query: 93  PPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQV 152
             GGI  VTVN+SLL+PL +E+DP IQ VR QE+EQIK LNNKFASFIDKVRFLEQQN++
Sbjct: 59  GMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKM 118

Query: 153 LETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYK 212
           LETKW+LLQQ      R N++ ++E YI+NL++QLE L  + ++L++EL NMQ LVED+K
Sbjct: 119 LETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFK 176

Query: 213 KRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQ 272
            +YE EIN+RT  ENEFV++KKDVD AYMNKVEL+++++ LTDEI F + LYE EI ++Q
Sbjct: 177 NKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQ 236

Query: 273 SHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQH 332
           S ISDTS+VLSMDN+R LD+DSIIAEV+AQYE+IA +S+AEAE++YQ K +ELQ  AG+H
Sbjct: 237 SQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKH 296

Query: 333 GDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDEL 392
           GDDL+ TK EISE+NR I R+++EI  +K Q A LE AIADAEQRG+ A+KDA AKL EL
Sbjct: 297 GDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSEL 356

Query: 393 EGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS 452
           E AL +AK+++AR LREYQEL+++KLALD+EIATYRKLLE EE R+     N   +S+ +
Sbjct: 357 EAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQN---MSIHT 413

Query: 453 STNAG-AGGAGFSMGFGASSSYSYKTAAADVKTKGS 487
            T +G AGG   + G   S   SY   ++     GS
Sbjct: 414 KTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGS 449


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  459 bits (1181), Expect = e-129
 Identities = 263/509 (51%), Positives = 343/509 (67%), Gaps = 32/509 (6%)

Query: 15  GFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLS----CLGGSRSLALSAAARRGGGR 70
           GFS  SA  +   G S   F +R      F S+SL+    CL GSR     +     GGR
Sbjct: 11  GFSARSACSARSRGRSRGGFSSR----GGFSSRSLNSFGGCLEGSRGSTWGS-----GGR 61

Query: 71  LGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130
           LG   G   G  GL     S+CPPGGI +VT+N++LL PL +E+DP+ Q VR QE ++I+
Sbjct: 62  LGVRFGEWSGGPGL-----SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIR 116

Query: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190
            LNN+FASFIDKVRFLEQQN+VLETKW+LLQQ  L+  ++ LEP++E  +  L+KQLE L
Sbjct: 117 TLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQL 176

Query: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250
            G+   LD+EL+  +D  E+YK +YE E +RR   EN+FVVLKKDVD  +++K+EL+ K+
Sbjct: 177 QGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKL 236

Query: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310
           ++L + + F K L E E+ Q+Q+  SDTS+VLSMDNNR LD  SII EVRA+YEEIA  S
Sbjct: 237 EALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSS 296

Query: 311 KAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETA 370
           KAEAE LYQTK QELQV+A  HGD ++ TK +IS+L++ IQR++S+  N+KKQ A L+ A
Sbjct: 297 KAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAA 356

Query: 371 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 430
           I DAEQRG+ ALKDA+AK+DELE AL  AK+ LAR+L EYQEL S KL+LD+EIATYR+L
Sbjct: 357 ITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRL 416

Query: 431 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFG---ASSSYSYKTAAADVKTKGS 487
           LE EECRMSGE  + V+IS +  +   +GG G  +G      S   S  +    + T GS
Sbjct: 417 LEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGS 476

Query: 488 ---CGSELKDPL-------AKTSGSSCAT 506
               GS  KDP+         ++GSSC T
Sbjct: 477 NIILGSG-KDPVLDSCSVSGSSAGSSCHT 504


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  431 bits (1108), Expect = e-121
 Identities = 258/528 (48%), Positives = 335/528 (63%), Gaps = 50/528 (9%)

Query: 11  GERLG-FSGCSAVLSGGIG-----SSSASFRARVKGSASFGSKSLSCLGG--SRSLALSA 62
           G R+G FS CSA+    +      S S       +G  SFGS+S+   G    R  A+ +
Sbjct: 11  GHRVGNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGS 70

Query: 63  AARRGGGRLGGFVGTAFGSA---GLGPKCPSVCPPG-----------------------G 96
                G R G   G  FG     GLGP+  S    G                       G
Sbjct: 71  RPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVG 130

Query: 97  IPQ------VTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQN 150
           +P       VTVNKSLL PLN+E+DP  QRV+  E+EQIK LNNKFASFIDKVRFLEQQN
Sbjct: 131 VPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQN 190

Query: 151 QVLETKWNLLQQLDLNNC-RKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVE 209
           ++LETKW+ LQ+     C R NLEP++E YI+NL++QLE+L  D  RL +E  ++QD++E
Sbjct: 191 KLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLE 247

Query: 210 DYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEIT 269
            +KK+YE E+  R  AENEFV LKKDVDAA+MNK +L+A VD+LT EI F K LY  EI 
Sbjct: 248 GFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQ 307

Query: 270 QIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTA 329
            +QSHIS+TS+++ MDN+RDL+LD IIAEV+AQYEE+A +S+A+AE  YQTK +E+QVTA
Sbjct: 308 LLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTA 367

Query: 330 GQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKL 389
           GQH D+L+  + EI+EL RLIQR+++EI + K Q A LE A+A+AEQ+G+  L DA+ KL
Sbjct: 368 GQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKL 427

Query: 390 DELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSIS 449
            +LE AL QAK+++AR L EYQEL++ KL LD+EIATYR+LLE EE R+  E    V+IS
Sbjct: 428 ADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNIS 486

Query: 450 VISSTNAGAGG-----AGFSMGFGASSSYSYKTAAADVKTKGSCGSEL 492
           V SS      G     AG ++  G  +     +  A      SCG  L
Sbjct: 487 VSSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSL 534


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  407 bits (1047), Expect = e-114
 Identities = 249/522 (47%), Positives = 333/522 (63%), Gaps = 36/522 (6%)

Query: 8   FPRGERLG---FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA----- 59
           F  G R G   FS  SAV+   +   + S +   +     G ++L CLG SRSL      
Sbjct: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVS-KGPCRPGGGRGLRALGCLG-SRSLCNVGFG 63

Query: 60  LSAAARRGGGRLGGFVGTAFGSAGLGPKC-PSVCPPGGIPQVTVNKSLLAPLNVEMDPEI 118
               A R GG L GF         LG  C PS C    I  VT+N+SLL PL +E+DP +
Sbjct: 64  RPRVASRCGGTLPGF------GYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTV 113

Query: 119 QRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEG 178
           QRV+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKWN +QQ     C+ N+EPI+EG
Sbjct: 114 QRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEG 171

Query: 179 YISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDA 238
           YIS L++QL+ +SGD VRL+SEL ++Q  +E YKK+YE E++ R   ENEFV LKKDVD 
Sbjct: 172 YISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDT 231

Query: 239 AYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAE 298
           A++ K +L+   ++L  EI F K LYE EI  +QS IS+TS+++ MDN+R+LD+D IIAE
Sbjct: 232 AFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAE 291

Query: 299 VRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIG 358
           ++AQY++IA +SKAEAE  YQ + +EL+VTAG H D+L+  K EI E+N+LIQR++ E  
Sbjct: 292 IKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETE 351

Query: 359 NVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKL 418
           NVK Q   LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+++ KL
Sbjct: 352 NVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKL 411

Query: 419 ALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA------GAGGAGFSMGF----G 468
            LD+EIATYR+LLE EE R+  E    V+ISV SS  A      G      S G     G
Sbjct: 412 GLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470

Query: 469 ASSSYSYKTAAADVKTKG--SCGSELKDPLAKTSGSSCATKK 508
             S           + +G  SCGS  K  +   +G S  + K
Sbjct: 471 GCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  406 bits (1044), Expect = e-113
 Identities = 229/461 (49%), Positives = 316/461 (68%), Gaps = 20/461 (4%)

Query: 11  GERLGFSGCSAVL---SGGIGSSSASFR--ARVKGSASFGSKSLSCLGGSRSLALSAAAR 65
           G    FS CSAV          S+A +R  +  +G   FGS+SL  LG       S   R
Sbjct: 13  GVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLG-------SCGPR 65

Query: 66  RG-GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQ 124
              GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +
Sbjct: 66  IAVGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQE 122

Query: 125 EREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQ 184
           E+EQIK+LN++FA+FIDKVRFLEQQN++LETKW   Q  +   C  NLEP++ GYI  L+
Sbjct: 123 EKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESNLEPLFSGYIETLR 180

Query: 185 KQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKV 244
           ++ E +  D  RL SEL ++Q+++E YKK+YE E+  R  AENEFVVLKKDVD AY+ K 
Sbjct: 181 REAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKS 240

Query: 245 ELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYE 304
           +L+A V++L +E  F + LYE EI  +Q+HISDTS+++ MDN+RDL++D IIAE++AQY+
Sbjct: 241 DLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYD 300

Query: 305 EIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQC 364
           ++A +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +EI N K Q 
Sbjct: 301 DVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQR 360

Query: 365 ADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEI 424
           A LE A+A+AEQ+G+ AL DAR KL ELEGAL +AK+++A +L+EYQE+++ KL LD+EI
Sbjct: 361 AKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEI 420

Query: 425 ATYRKLLESEECRMSGEYPNSVSISVISST-NAGAGGAGFS 464
           ATYR+LLE EE R+  E   SV++ V SS      GG  +S
Sbjct: 421 ATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGGLSYS 460


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  392 bits (1007), Expect = e-109
 Identities = 215/430 (50%), Positives = 304/430 (70%), Gaps = 21/430 (4%)

Query: 42  ASFGSKSLSCLG--GSRS--LALSAAARRG----GGRLGGFV------GTAFGSAG--LG 85
           + FG ++ SC+   G R     ++AA  RG     G  GGF       G   GS G   G
Sbjct: 5   SGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRSFG 64

Query: 86  PKCPSVCPPGG--IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKV 143
            +   VC P    I  V+VN+SLL PLN+E+DP  Q V+ +E+EQIK+LN++FA+FIDKV
Sbjct: 65  YRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 124

Query: 144 RFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRN 203
           RFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ E +  D  RL SEL +
Sbjct: 125 RFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREAECVEADSGRLASELNH 182

Query: 204 MQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCL 263
           +Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+A V++L  EI F + L
Sbjct: 183 VQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 242

Query: 264 YEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQ 323
           YE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I  +S+AEAE+ Y++K +
Sbjct: 243 YEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSKCE 302

Query: 324 ELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALK 383
           E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + LE A+A +EQ+G+ AL 
Sbjct: 303 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 362

Query: 384 DARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYP 443
           DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATYR+LLE EE R+  E  
Sbjct: 363 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLC-EGI 421

Query: 444 NSVSISVISS 453
            +V++ V SS
Sbjct: 422 GAVNVCVSSS 431


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108

Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166

Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226

Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286

Query: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346

Query: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406

Query: 428 RKLLESEECRMSGEYPNSVSISVISS 453
           R+LLE EE R+  E   SV++ V SS
Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108

Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166

Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226

Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286

Query: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346

Query: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406

Query: 428 RKLLESEECRMSGEYPNSVSISVISS 453
           R+LLE EE R+  E   SV++ V SS
Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108

Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166

Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226

Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286

Query: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346

Query: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406

Query: 428 RKLLESEECRMSGEYPNSVSISVISS 453
           R+LLE EE R+  E   SV++ V SS
Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  391 bits (1005), Expect = e-109
 Identities = 204/386 (52%), Positives = 286/386 (74%), Gaps = 6/386 (1%)

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 52  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 108

Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++EGYI  L+++ 
Sbjct: 109 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFEGYIETLRREA 166

Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
           E +  D  RL SEL ++Q+++E YKK+YE E++ R  AENEFV LKKDVD AY+ K +L+
Sbjct: 167 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLE 226

Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D IIAE++AQY++I 
Sbjct: 227 ANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIV 286

Query: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 287 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 346

Query: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 347 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 406

Query: 428 RKLLESEECRMSGEYPNSVSISVISS 453
           R+LLE EE R+  E   SV++ V SS
Sbjct: 407 RRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  387 bits (995), Expect = e-107
 Identities = 202/386 (52%), Positives = 285/386 (73%), Gaps = 6/386 (1%)

Query: 68  GGRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQERE 127
           GG   G  G +FG    G   PS   P  I  V+VN+SLL PLN+E+DP  Q V+ +E+E
Sbjct: 57  GGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKE 113

Query: 128 QIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQL 187
           QIK+LN++FA+FIDKVRFLEQQN++LETK    Q  +   C+ NLEP++ GYI  L+++ 
Sbjct: 114 QIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPLFAGYIETLRREA 171

Query: 188 EMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQ 247
           E +  D  RL SEL ++Q+++E YKK+YE E+  R  AENEFV LKKDVD AY+ K +L+
Sbjct: 172 ECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLE 231

Query: 248 AKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIA 307
           A V++L  EI F + LYE EI  +QSHISDTS+V+ +DN+RDL++D I+AE++AQY++IA
Sbjct: 232 ANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIA 291

Query: 308 LKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADL 367
            +S+AEAE+ Y++K +E++ T  +HG+ L+ TK EI+ELNR+IQR+ +E+ N K Q + L
Sbjct: 292 TRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKL 351

Query: 368 ETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATY 427
           E A+A +EQ+G+ AL DAR KL ELEGAL +AK+++A ++REYQE+++ KL LD+EIATY
Sbjct: 352 EAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATY 411

Query: 428 RKLLESEECRMSGEYPNSVSISVISS 453
           R+LLE EE R+  E   +V++ V SS
Sbjct: 412 RRLLEGEEQRLC-EGVEAVNVCVSSS 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.130    0.356 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,786,477
Number of Sequences: 37866
Number of extensions: 712869
Number of successful extensions: 5134
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 169
Number of HSP's successfully gapped in prelim test: 455
Number of HSP's that attempted gapping in prelim test: 3592
Number of HSP's gapped (non-prelim): 1486
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.