Search of human proteins with 28173564

Search of human proteins with 28173564

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28173564 keratin 73 [Homo sapiens]
         (540 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28173564 keratin 73 [Homo sapiens]                                1054   0.0  
gi|15618995 keratin 71 [Homo sapiens]                                 836   0.0  
gi|148612803 keratin 6 irs4 [Homo sapiens]                            725   0.0  
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       701   0.0  
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      701   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 582   e-166
gi|5031839 keratin 6A [Homo sapiens]                                  579   e-165
gi|109255249 keratin 4 [Homo sapiens]                                 578   e-165
gi|119703753 keratin 6B [Homo sapiens]                                578   e-165
gi|155969697 keratin 6C [Homo sapiens]                                574   e-164
gi|119395750 keratin 1 [Homo sapiens]                                 559   e-159
gi|153791670 keratin 76 [Homo sapiens]                                559   e-159
gi|109148552 keratin 3 [Homo sapiens]                                 559   e-159
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      559   e-159
gi|153791158 keratin 75 [Homo sapiens]                                559   e-159
gi|194018511 keratin 77 [Homo sapiens]                                551   e-157
gi|47132620 keratin 2 [Homo sapiens]                                  546   e-155
gi|32567786 keratin 6L [Homo sapiens]                                 538   e-153
gi|89357932 keratin 5b [Homo sapiens]                                 482   e-136
gi|67782365 keratin 7 [Homo sapiens]                                  473   e-133
gi|4504919 keratin 8 [Homo sapiens]                                   463   e-130
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    439   e-123
gi|4504935 keratin 85 [Homo sapiens]                                  422   e-118
gi|27477127 keratin 82 [Homo sapiens]                                 416   e-116
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   400   e-111
gi|169790841 keratin 83 [Homo sapiens]                                400   e-111
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   396   e-110
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   396   e-110
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   396   e-110
gi|14318422 keratin 86 [Homo sapiens]                                 396   e-110

>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score = 1054 bits (2726), Expect = 0.0
 Identities = 540/540 (100%), Positives = 540/540 (100%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFN 60
           MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFN
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFN 60

Query: 61  VASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVE 120
           VASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVE
Sbjct: 61  VASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVE 120

Query: 121 LDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 180
           LDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE
Sbjct: 121 LDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 180

Query: 181 PILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLK 240
           PILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLK
Sbjct: 181 PILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLK 240

Query: 241 KDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLD 300
           KDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLD
Sbjct: 241 KDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLD 300

Query: 301 SIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRL 360
           SIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRL
Sbjct: 301 SIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRL 360

Query: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420
           RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL
Sbjct: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420

Query: 421 LSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTY 480
           LSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTY
Sbjct: 421 LSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTY 480

Query: 481 GYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR 540
           GYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR
Sbjct: 481 GYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR 540


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  836 bits (2159), Expect = 0.0
 Identities = 439/541 (81%), Positives = 480/541 (88%), Gaps = 19/541 (3%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFN 60
           MSRQFT KSGAAAKGGFSGCSAVLSGGSSSS+RAG KGLSGGF SRSLYSLGG RS+  N
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSL--N 58

Query: 61  VASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVE 120
           VASGSG +GGYGFGRGRASGFAGSMFGSVALG VCP++CPPGGIHQVT+N+SLLAPLNVE
Sbjct: 59  VASGSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVE 118

Query: 121 LDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 180
           LDPEIQKVRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE
Sbjct: 119 LDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLE 178

Query: 181 PILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLK 240
           PILEGYISNLRKQLETLSGDRVRLDSELR+VR+VVEDYKKRYEEEINKRT AENEFV+LK
Sbjct: 179 PILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLK 238

Query: 241 KDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLD 300
           KDVDAAY +KVELQAKV+++D EIKFF+CL+E E  QIQSHISD S+ILSMDNNRNLDLD
Sbjct: 239 KDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLD 298

Query: 301 SIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRL 360
           SII EVR QYEEIA KSKAEAEALYQTKFQELQLAAGRHGDDLK+TKNEISELTRLIQR+
Sbjct: 299 SIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRI 358

Query: 361 RSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQEL 420
           RSEIE+VKKQ +NLETAIADAEQRGD ALKDARAKLDELEGAL QAKEELARMLREYQEL
Sbjct: 359 RSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQEL 418

Query: 421 LSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTY 480
           +S+KL+LD+EIATYRKLLE EECRMSGE+ + VSIS+I+S+  G               Y
Sbjct: 419 MSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISSTSGG-------------SVY 465

Query: 481 GYWPSSVSGGYSMLPGGCVTGSGNCSPR-GEARTRLGSASEFRDSQGKTLALSSPTKKTM 539
           G+ PS VSGGY      C+  SG CS R GE R+R GSA++++D+ GK  +LS+P+KKT 
Sbjct: 466 GFRPSMVSGGYVANSSNCI--SGVCSVRGGEGRSR-GSANDYKDTLGKGSSLSAPSKKTS 522

Query: 540 R 540
           R
Sbjct: 523 R 523


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  725 bits (1871), Expect = 0.0
 Identities = 397/549 (72%), Positives = 438/549 (79%), Gaps = 29/549 (5%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVL---SGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57
           MSRQ   KS +  KG FS  SAV+   + GS +SY A G+G   GF SRSLYSLGG R I
Sbjct: 1   MSRQLNIKS-SGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRI 59

Query: 58  SFNVASGSGWAGGYGF------GRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINK 111
           SFNVA G   AGGYGF      G GRASGFAGSMFGSVALG  C S+CPPGGIHQVT+NK
Sbjct: 60  SFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNK 119

Query: 112 SLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLD 171
           SLLAPLNVELDPEIQKVRAQEREQIKVLN+KFASFIDKVRFLEQQNQVLETKWELLQQLD
Sbjct: 120 SLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLD 179

Query: 172 LNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTT 231
           LNNCK NLEPILEGYISNLRKQLETLSGDRVRLDSELRS+R++VEDYKKRYE EIN+RTT
Sbjct: 180 LNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTT 239

Query: 232 AENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSM 291
           AENEFVVLKKD DAAY  KVELQAKVD+LD EIKF KCLY+ E AQIQ+H S+TS+ILSM
Sbjct: 240 AENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSM 299

Query: 292 DNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIS 351
           DNNR+LDLDSIIAEVR  YEEIA KSKAEAEALYQTK QELQLAA RHGDDLKHT++E+ 
Sbjct: 300 DNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMV 359

Query: 352 ELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELA 411
           EL RLIQR+R EI +VKKQ A+LETAIADAEQRGD ALKDA+AKLDELEGAL QAKEELA
Sbjct: 360 ELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELA 419

Query: 412 RMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAG 471
           RMLREYQEL+S+KL+LD+EIATYRKLLEGEECRMSGE  +SVSISVI+SS          
Sbjct: 420 RMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSS---------- 469

Query: 472 FGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLAL 531
                  +Y Y   S +G    L    V GS   +  G+ +T      + +D+QGK+   
Sbjct: 470 -------SYSYHHPSSAG--VDLGASAVAGSSGSTQSGQTKTTEARGGDLKDTQGKSTPA 520

Query: 532 SSPTKKTMR 540
           S P +K  R
Sbjct: 521 SIPARKATR 529


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  701 bits (1809), Expect = 0.0
 Identities = 380/543 (69%), Positives = 426/543 (78%), Gaps = 35/543 (6%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGG---SSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57
           MSRQ T+      + GFSGCSAVLSGG   SS+S+RA  KG S  F S+SL  LGG+RS+
Sbjct: 1   MSRQLTHFP-RGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58

Query: 58  SFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPL 117
           + + A+  G         GR  GF G+ FGS  LG  CPS+CPPGGI QVT+NKSLLAPL
Sbjct: 59  ALSAAARRGG--------GRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPL 110

Query: 118 NVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 177
           NVE+DPEIQ+VRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ 
Sbjct: 111 NVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRK 170

Query: 178 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFV 237
           NLEPI EGYISNL+KQLE LSGD VRLDSELR+++++VEDYKKRYE EIN+RT AENEFV
Sbjct: 171 NLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFV 230

Query: 238 VLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNL 297
           VLKKDVDAAY +KVELQAKVD+L  EIKFFKCLYEGE  QIQSHISDTSI+LSMDNNR+L
Sbjct: 231 VLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDL 290

Query: 298 DLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLI 357
           DLDSIIAEVRAQYEEIA KSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLI
Sbjct: 291 DLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLI 350

Query: 358 QRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREY 417
           QR+RSEI +VKKQCA+LETAIADAEQRGDCALKDARAKLDELEGAL QAKEELARMLREY
Sbjct: 351 QRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREY 410

Query: 418 QELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNA 477
           QEL+S+KL+LD+EIATYRKLLE EECRMSGEY NSVSISVI+S+ AG  G G   GF  +
Sbjct: 411 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGAS 470

Query: 478 GTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKK 537
            +Y Y  ++                       + +T+    SE +D   KT   S  TKK
Sbjct: 471 SSYSYKTAA----------------------ADVKTKGSCGSELKDPLAKTSGSSCATKK 508

Query: 538 TMR 540
             R
Sbjct: 509 ASR 511


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  701 bits (1809), Expect = 0.0
 Identities = 380/543 (69%), Positives = 426/543 (78%), Gaps = 35/543 (6%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGG---SSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57
           MSRQ T+      + GFSGCSAVLSGG   SS+S+RA  KG S  F S+SL  LGG+RS+
Sbjct: 1   MSRQLTHFP-RGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58

Query: 58  SFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPL 117
           + + A+  G         GR  GF G+ FGS  LG  CPS+CPPGGI QVT+NKSLLAPL
Sbjct: 59  ALSAAARRGG--------GRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPL 110

Query: 118 NVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 177
           NVE+DPEIQ+VRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ 
Sbjct: 111 NVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRK 170

Query: 178 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFV 237
           NLEPI EGYISNL+KQLE LSGD VRLDSELR+++++VEDYKKRYE EIN+RT AENEFV
Sbjct: 171 NLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFV 230

Query: 238 VLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNL 297
           VLKKDVDAAY +KVELQAKVD+L  EIKFFKCLYEGE  QIQSHISDTSI+LSMDNNR+L
Sbjct: 231 VLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDL 290

Query: 298 DLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLI 357
           DLDSIIAEVRAQYEEIA KSKAEAE LYQTK QELQ+ AG+HGDDLK TK EISEL RLI
Sbjct: 291 DLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLI 350

Query: 358 QRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREY 417
           QR+RSEI +VKKQCA+LETAIADAEQRGDCALKDARAKLDELEGAL QAKEELARMLREY
Sbjct: 351 QRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREY 410

Query: 418 QELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNA 477
           QEL+S+KL+LD+EIATYRKLLE EECRMSGEY NSVSISVI+S+ AG  G G   GF  +
Sbjct: 411 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGAS 470

Query: 478 GTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKK 537
            +Y Y  ++                       + +T+    SE +D   KT   S  TKK
Sbjct: 471 SSYSYKTAA----------------------ADVKTKGSCGSELKDPLAKTSGSSCATKK 508

Query: 538 TMR 540
             R
Sbjct: 509 ASR 511


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  582 bits (1499), Expect = e-166
 Identities = 318/590 (53%), Positives = 415/590 (70%), Gaps = 51/590 (8%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSY----RAGGKGLSG-------------GF 43
           MSRQ +    +     FS  SA+    S +S+    R+GG G  G             G+
Sbjct: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60

Query: 44  SSRSLYSLGGARSISFNVASGS-------GWAGGYGFGRGRASGFA-------------G 83
            SRSLY+LGG++ IS + + GS       G  GGYGFG G  SGF              G
Sbjct: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120

Query: 84  SMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKF 143
           + FG    G   P +CPPGGI +VT+N+SLL PLN+++DP IQ+VR +EREQIK LNNKF
Sbjct: 121 AGFGGGFGGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179

Query: 144 ASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVR 203
           ASFIDKVRFLEQQN+VL+TKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R R
Sbjct: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239

Query: 204 LDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGE 263
           LDSELR+++++VED+K +YE+EINKRTTAENEFV+LKKDVDAAY +KVEL+AKVDAL  E
Sbjct: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299

Query: 264 IKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEA 323
           I F K  ++ E +Q+Q+H+SDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA +S+ EAE+
Sbjct: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359

Query: 324 LYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQ 383
            YQTK++ELQ  AGRHGDDL++TK+EISE+ R+IQRLR+EI++VKKQCANL+ AIADAEQ
Sbjct: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419

Query: 384 RGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEEC 443
           RG+ ALKDAR KL ELE ALQ+AK+++AR+LREYQEL++ KL+LD+EIATYRKLLEGEEC
Sbjct: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479

Query: 444 RMSGEYTNSVSISVINSSMAGMAGTGAGFGFS-------------NAGTYGYWPSSVSGG 490
           R+SGE    V+ISV+ SS++   G+G+G+G                 G+ G + SS SGG
Sbjct: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539

Query: 491 YSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR 540
             +  G  V GSG  +  G        +     S  K ++ +S ++K+ +
Sbjct: 540 VGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  579 bits (1493), Expect = e-165
 Identities = 317/548 (57%), Positives = 401/548 (73%), Gaps = 38/548 (6%)

Query: 2   SRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA-------GGKGLSG-----GFSSRSLY 49
           S   T +S ++++ GFS  SA L G S S + +       G  GL G     GF SRSLY
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLY 62

Query: 50  SLGGARSISFNVAS-------GSGWAGGYGFGRGRASGF-----AGSMFG-----SVALG 92
            LGG++ IS    S       GS   G YGFG G  SGF     AG  FG      +A G
Sbjct: 63  GLGGSKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGG 121

Query: 93  SVCPS--LCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKV 150
              P   +CPPGGI +VT+N+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 122 FGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKV 181

Query: 151 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRS 210
           RFLEQQN+VLETKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R RLDSELR 
Sbjct: 182 RFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRG 241

Query: 211 VREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCL 270
           ++++VED+K +YE+EINKRT AENEFV LKKDVDAAY +KVELQAK D L  EI F + L
Sbjct: 242 MQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301

Query: 271 YEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQ 330
           Y+ E +Q+Q+HISDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA++S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361

Query: 331 ELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALK 390
           ELQ+ AGRHGDDL++TK EI+E+ R+IQRLRSEI+ VKKQCANL+ AIADAEQRG+ ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421

Query: 391 DARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYT 450
           DA+ KL+ LE ALQ+AK++LAR+L+EYQEL++VKL+LD+EIATYRKLLEGEECR++GE  
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481

Query: 451 NSVSISVINSSMA----GMAGTGAGFGFSNAGTYGYWPS-SVSGGYSMLPGGCVTGSGNC 505
             V+ISV+ S+++    G +G G+G G     +Y Y     V GG+S   G  + G G  
Sbjct: 482 GQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSSSSGRAI-GGGLS 540

Query: 506 SPRGEART 513
           S  G + T
Sbjct: 541 SVGGGSST 548


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  578 bits (1491), Expect = e-165
 Identities = 319/506 (63%), Positives = 392/506 (77%), Gaps = 29/506 (5%)

Query: 16  GFSGCSAVLSGGS----SSSYRAGGKGL--SGGFSSRSLYSLGGARSISFNVASGS---- 65
           GFS  SA++ GG     SS   +GG G   SGGF SRSLY+L G +SIS +VA       
Sbjct: 88  GFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGAC 147

Query: 66  -GWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPE 124
            G AGG+G G G   GF GS  G    G     +CP GGI +VTIN+SLL PL+VE+DPE
Sbjct: 148 FGGAGGFGTG-GFGGGFGGSFSGKGGPGF---PVCPAGGIQEVTINQSLLTPLHVEIDPE 203

Query: 125 IQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILE 184
           IQKVR +EREQIK+LNNKFASFIDKV+FLEQQN+VLETKW LLQQ        NLEP+ E
Sbjct: 204 IQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFE 263

Query: 185 GYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVD 244
            Y+S LRKQL+TL  D+ RL SEL+++++ VED+K +YEEEINKRT AEN+FVVLKKDVD
Sbjct: 264 TYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVD 323

Query: 245 AAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIA 304
           AAY +KVEL+AKVD+L+ EI F K LY+ E +Q+Q+H+SDTS++LSMDNNRNLDLDSIIA
Sbjct: 324 AAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIA 383

Query: 305 EVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEI 364
           EVRAQYEEIA++SKAEAEALYQTK Q+LQ++  +HGD+LK+TK+EI+EL R+IQRLR+EI
Sbjct: 384 EVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEI 443

Query: 365 ESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVK 424
           E++KKQC  L+ ++ADAEQRG+ ALKDA +K  ELE ALQQAKEELARMLREYQEL+SVK
Sbjct: 444 ENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 503

Query: 425 LSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSS-----MAGMAGTGAGFGFSNAGT 479
           L+LDIEIATYRKLLEGEE RMSGE  ++VSISV++ S     ++G  G+G+GFG S+   
Sbjct: 504 LALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGGISGGLGSGSGFGLSS--- 560

Query: 480 YGYWPSSVSG-GYSMLPGGCVTGSGN 504
            G+   S SG G+    GG V+GS +
Sbjct: 561 -GFGSGSGSGFGF----GGSVSGSSS 581



 Score = 29.3 bits (64), Expect = 9.6
 Identities = 21/63 (33%), Positives = 29/63 (46%), Gaps = 15/63 (23%)

Query: 22  AVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWAGGYGFGRGRASGF 81
           +V+SG +S+   +GG G   GF   S +              GSG   G+GFG G  SG 
Sbjct: 535 SVVSGSTSTGGISGGLGSGSGFGLSSGF--------------GSGSGSGFGFG-GSVSGS 579

Query: 82  AGS 84
           + S
Sbjct: 580 SSS 582


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  578 bits (1490), Expect = e-165
 Identities = 317/548 (57%), Positives = 400/548 (72%), Gaps = 38/548 (6%)

Query: 2   SRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA-------GGKGLSG-----GFSSRSLY 49
           S   T +S ++++ GFS  SA L G S S + +       G  GL G     GF SRSLY
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLY 62

Query: 50  SLGGARSISFNVAS-------GSGWAGGYGFGRGRASGF-----AGSMFG-----SVALG 92
            LGG++ IS    S       GS   G YGFG G  SGF     AG  FG      +A G
Sbjct: 63  GLGGSKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGG 121

Query: 93  SVCPS--LCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKV 150
              P   +CPPGGI +VT+N+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 122 FGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181

Query: 151 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRS 210
           RFLEQQN+VL+TKW LLQ+      + NLEP+ E YI+NLR+QL+ + G+R RLDSELR+
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRN 241

Query: 211 VREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCL 270
           ++++VED K +YE+EINKRT AENEFV LKKDVDAAY +KVELQAK D L  EI F + L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301

Query: 271 YEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQ 330
           Y+ E +Q+Q+HISDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA++S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361

Query: 331 ELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALK 390
           ELQ+ AGRHGDDL++TK EI+E+ R+IQRLRSEI+ VKKQCANL+ AIADAEQRG+ ALK
Sbjct: 362 ELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALK 421

Query: 391 DARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYT 450
           DA+ KL+ LE ALQ+AK++LAR+L+EYQEL++VKL+LD+EIATYRKLLEGEECR++GE  
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481

Query: 451 NSVSISVINSSMA----GMAGTGAGFGFSNAGTYGYWPS-SVSGGYSMLPGGCVTGSGNC 505
             V+ISV+ S+++    G +G G+G G     +Y Y     V GG+S    G  TG G  
Sbjct: 482 GQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGGGFSS-SSGRATGGGLS 540

Query: 506 SPRGEART 513
           S  G + T
Sbjct: 541 SVGGGSST 548


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  574 bits (1480), Expect = e-164
 Identities = 313/548 (57%), Positives = 401/548 (73%), Gaps = 38/548 (6%)

Query: 2   SRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA-------GGKGLSG-----GFSSRSLY 49
           S   T +S ++++ GFS  SA L G S S + +       G  GL G     GF SRSLY
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLY 62

Query: 50  SLGGARSISFNVAS-------GSGWAGGYGFGRGRASGF-----AGSMFG-----SVALG 92
            LGG++ IS    S       GS   G YGFG G  SGF     AG  FG      +A G
Sbjct: 63  GLGGSKRISIGGGSCAISGGYGSRAGGSYGFG-GAGSGFGFGGGAGIGFGLGGGAGLAGG 121

Query: 93  SVCPS--LCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKV 150
              P   +CPPGGI +VT+N+SLL PLN+++DP IQ+VRA+EREQIK LNNKFASFIDKV
Sbjct: 122 FGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKV 181

Query: 151 RFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRS 210
           RFLEQQN+VL+TKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R RLDSELR+
Sbjct: 182 RFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRN 241

Query: 211 VREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCL 270
           ++++VED K +YE+EINKRT AENEFV LKKDVDAAY +KVELQAK D L  EI F + L
Sbjct: 242 MQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRAL 301

Query: 271 YEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQ 330
           Y+ E +Q+Q+HISDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA++S+AEAE+ YQTK++
Sbjct: 302 YDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYE 361

Query: 331 ELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALK 390
           ELQ+ AGRHGDDL++TK EI+E+ R+IQRLRSEI+ VKKQCA+L+ AIADAEQRG+ ALK
Sbjct: 362 ELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALK 421

Query: 391 DARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYT 450
           DA+ KL+ LE ALQ+AK++LAR+L+EYQEL++VKL+LD+EIATYRKLLEGEECR++GE  
Sbjct: 422 DAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGV 481

Query: 451 NSVSISVINSSMA----GMAGTGAGFGFSNAGTYGYWPS-SVSGGYSMLPGGCVTGSGNC 505
             V++SV+ S+++    G +G G+G G     +Y Y     + GG+S   G  + G G  
Sbjct: 482 GQVNVSVVQSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGGGFSSSSGRAI-GGGLS 540

Query: 506 SPRGEART 513
           S  G + T
Sbjct: 541 SVGGGSST 548


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  559 bits (1441), Expect = e-159
 Identities = 314/568 (55%), Positives = 398/568 (70%), Gaps = 59/568 (10%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSG-----GSSSSYRAGGKG--------------LSG 41
           MSRQF+ +SG  + GGFS  SA +        SSS+ R+GG G                G
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60

Query: 42  GFSSRSLYSLGGARSISFNVASG----SGWAGGYG------------------------- 72
           GF SRSL +LGG++SIS +VA G    SG+ GGYG                         
Sbjct: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120

Query: 73  -FGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQ 131
            FG G   GF G  FG    G     +CPPGGI +VTIN+SLL PLNVE+DPEIQKV+++
Sbjct: 121 GFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179

Query: 132 EREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLR 191
           EREQIK LNN+FASFIDKVRFLEQQNQVL+TKWELLQQ+D +   +NLEP  E +I+NLR
Sbjct: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239

Query: 192 KQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKV 251
           ++++ L  D+ RLDSEL++++++VEDY+ +YE+EINKRT AENEFV +KKDVD AY +KV
Sbjct: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299

Query: 252 ELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYE 311
           +LQAK+D L  EI F   LY+ E +Q+Q+ IS+T++ILSMDNNR+LDLDSIIAEV+AQYE
Sbjct: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359

Query: 312 EIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQC 371
           +IA+KSKAEAE+LYQ+K++ELQ+ AGRHGD ++++K EISEL R+IQRLRSEI++VKKQ 
Sbjct: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419

Query: 372 ANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEI 431
           +NL+ +I+DAEQRG+ ALKDA+ KL++LE ALQQAKE+LAR+LR+YQEL++ KL+LD+EI
Sbjct: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479

Query: 432 ATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGY 491
           ATYR LLEGEE RMSGE   +VS+SV  S      G   G G    G YG      SGG 
Sbjct: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGG---GGGYG------SGGS 530

Query: 492 SMLPGGCVTGSGNCSPRGEARTRLGSAS 519
           S   GG   GSG     G      G +S
Sbjct: 531 SYGSGGGSYGSGGGGGGGRGSYGSGGSS 558



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 34/100 (34%), Positives = 43/100 (43%), Gaps = 3/100 (3%)

Query: 7   YKSGAAA--KGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASG 64
           Y SG ++   GG S  S    GG   SY +GG     G  S      GG      + +S 
Sbjct: 525 YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584

Query: 65  SGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGI 104
            G+ GG G G G +SG  GS  GS   GS+       GG+
Sbjct: 585 GGYRGGSGGGGGGSSGGRGSGGGSSG-GSIGGRGSSSGGV 623



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 37/92 (40%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 6   TYKSGAAAKGGF----SGCSAVLSGGSS--SSYRAGGKGLSGGFSSRSLY---SLGGARS 56
           +Y SG    GG     SG S+  SGG S  S    GG G  G  SS   Y   S GG   
Sbjct: 538 SYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGG 597

Query: 57  ISFNVASGSGWAGGYGFGRGRASGFAGSMFGS 88
            S    SG G +GG   GRG +SG   S  GS
Sbjct: 598 SSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGS 629



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 35/104 (33%), Positives = 42/104 (40%), Gaps = 15/104 (14%)

Query: 1   MSRQFTYKSGAAAKGGF-----SGCSAVLSGGSSSSYRAGGKGLSGGFSSR-SLYSLGGA 54
           +S   T  SG  ++GG      SG S+  SGG S     GG G  G + S  S Y  GG 
Sbjct: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG 564

Query: 55  RSISFNVASGSGWAGGYGFG------RGRASGFAGSMFGSVALG 92
              S+    G G  G YG G      RG + G  G   G    G
Sbjct: 565 ---SYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 6/66 (9%)

Query: 6   TYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSG-----GFSSRSLYSLGGARSISFN 60
           +Y SG+++ GG+ G S    GGSS    +GG    G     G SS  + S GG+ S+ F 
Sbjct: 577 SYGSGSSS-GGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFV 635

Query: 61  VASGSG 66
             + SG
Sbjct: 636 STTYSG 641


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  559 bits (1441), Expect = e-159
 Identities = 331/587 (56%), Positives = 410/587 (69%), Gaps = 60/587 (10%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSY--RAGGKGL--------SGGFSSRSLYS 50
           M+RQ   KS +    GFSG SAV+SG S  S   R+GG G         +G F SRSLY+
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYN 60

Query: 51  LGGARSISFNVASGS-------------GWAGGYGFG------------RGRASGFAGS- 84
           LG  +SIS +VA+GS             G+AGGYG G            RG  SGF G+ 
Sbjct: 61  LGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAG 120

Query: 85  ------------MFGSVALGSVCPSLCP---PGGIHQVTINKSLLAPLNVELDPEIQKVR 129
                       +FG            P   PGGI +V +N+SLL PLNVE+DP+I +V+
Sbjct: 121 GFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVK 180

Query: 130 AQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISN 189
           AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKWELLQQ    +  ++LEP  E YIS 
Sbjct: 181 AQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISF 240

Query: 190 LRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTS 249
           L KQL++L G+R  L+ EL+S++++VED+KK+YE+EINKRT AENEFV LKKDVDAA+ +
Sbjct: 241 LCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMN 300

Query: 250 KVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQ 309
           KVELQAKVD+L  E+ F + LYE E +Q+QSH SDTS++LSMDNNR LDL SIIAEVRAQ
Sbjct: 301 KVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQ 360

Query: 310 YEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKK 369
           YEEIA++SK+EAEALYQTK  ELQ  AGRHGDDL++TK+EI EL R+IQRLR+EIE+VKK
Sbjct: 361 YEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKK 420

Query: 370 QCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDI 429
           Q ANL+TAIA+AEQRG+ ALKDA AKL +L+ ALQ+AK++LAR+LR+YQEL++VKL+LD+
Sbjct: 421 QNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDV 480

Query: 430 EIATYRKLLEGEECRMSGEYTNSVSISVIN--SSMAGMAGTGAGF--GFSNAGTYGY--- 482
           EIATYRKLLEGEECRMSGE  ++V ISV++  +S +G +G+  G   G S +G+ GY   
Sbjct: 481 EIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGG 540

Query: 483 WPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTL 529
             SS S GY  + GG  +G G  S  G    R  S S    S G  L
Sbjct: 541 SSSSSSSGYG-VSGGSGSGYGGVS-SGSTGGRGSSGSYQSSSSGSRL 585



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 36/84 (42%), Positives = 42/84 (50%), Gaps = 14/84 (16%)

Query: 14  KGGFSGCSAV---LSGGSSSSY------RAGGKGLSGGFSSRSLYS-LGGARSISFNVAS 63
           KGG S  S+    +SGGS S Y        GG+G SG + S S  S LGGA SIS +  S
Sbjct: 538 KGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISVS-HS 596

Query: 64  GSGWAGG---YGFGRGRASGFAGS 84
           G G + G      G G  SG  GS
Sbjct: 597 GMGSSSGSIQTSGGSGYKSGGGGS 620


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  559 bits (1441), Expect = e-159
 Identities = 331/597 (55%), Positives = 403/597 (67%), Gaps = 80/597 (13%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRA--GGKGL--------SGGFSSRSLYS 50
           MSRQ +  SG  ++G FSG SAV+SG S  S  A  GG G         +GGF SRSLY+
Sbjct: 1   MSRQASKTSGGGSQG-FSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYN 59

Query: 51  LGGARSISFNVASGS-----------------------------GWAGGYGFGRGRASGF 81
           LGG +SIS +VA+G                              G+ GG+G GRG   GF
Sbjct: 60  LGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGF 119

Query: 82  AGS--------------------MFGSVALGSVCPSLCP--------PGGIHQVTINKSL 113
            G+                      GS   G       P        PGGI +VTIN+SL
Sbjct: 120 GGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQSL 179

Query: 114 LAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 173
           L PLNVE+DP+I +V+AQEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQQ   +
Sbjct: 180 LQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTS 239

Query: 174 NCK--NNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTT 231
           +    NNLEP+ E +I+ LR  L+ + G+R RLDSEL+++ ++VED+KK+YE+EINKRT 
Sbjct: 240 SISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTA 299

Query: 232 AENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSM 291
           AENEFV LKKDVD+AY +KVELQAKVDAL  EI F + LY+ E +Q+QSHISDTS++LSM
Sbjct: 300 AENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSM 359

Query: 292 DNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEIS 351
           DNNR+LDLDSIIAEVRAQYE+IA++SKAEAEALYQTK  ELQ  AGRHGDDL++TK+EI 
Sbjct: 360 DNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEII 419

Query: 352 ELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELA 411
           EL R+IQRLR+EIE VKKQ ANL+TAIA+AEQ G+ ALKDA AKL EL+ ALQQAK++LA
Sbjct: 420 ELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLA 479

Query: 412 RMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSS--MAGMAGTG 469
           R+LR+YQEL++VKL+LD+EIATYRKLLEGEE RMSGE  ++VSISV++SS   A   G G
Sbjct: 480 RLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYG 539

Query: 470 AGFGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQG 526
            G+G    G  G       GG+S   GG  +G G     G      G +S F    G
Sbjct: 540 GGYGGGMGGGLG-------GGFS-AGGGSGSGFGRGGGGGIGGGFGGGSSGFSGGSG 588



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 22/82 (26%)

Query: 11  AAAKGGFSGCSAVLSGGSSSSYRAG-GKGLSGGFSSRSLYSLGGARSISFNVASGSGWAG 69
           +A+ GG+ G            Y  G G GL GGFS+      GG     F    G G  G
Sbjct: 532 SASAGGYGG-----------GYGGGMGGGLGGGFSA------GGGSGSGFGRGGGGGIGG 574

Query: 70  GYGFGRGRASGFA-GSMFGSVA 90
           G+G   G +SGF+ GS FGS++
Sbjct: 575 GFG---GGSSGFSGGSGFGSIS 593



 Score = 36.6 bits (83), Expect = 0.060
 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 25/84 (29%)

Query: 10  GAAAKGGFSGCSAVLSGGSSSSY-RAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWA 68
           G    GGFS       GGS S + R GG G+ GGF   S                 SG++
Sbjct: 547 GGGLGGGFSA-----GGGSGSGFGRGGGGGIGGGFGGGS-----------------SGFS 584

Query: 69  GGYGFG--RGRASGFAGSMFGSVA 90
           GG GFG   G   G +G  F S +
Sbjct: 585 GGSGFGSISGARYGVSGGGFSSAS 608



 Score = 31.2 bits (69), Expect = 2.5
 Identities = 26/58 (44%), Positives = 33/58 (56%), Gaps = 6/58 (10%)

Query: 10  GAAAKGGFSGCSAVLSGGSSSSYRAGGK-GLS-GGFSSRSLYSLGGARSISFNVASGS 65
           G    GGF G S+  SGGS     +G + G+S GGFSS S  + GG  SI F+ +S S
Sbjct: 569 GGGIGGGFGGGSSGFSGGSGFGSISGARYGVSGGGFSSAS--NRGG--SIKFSQSSQS 622


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  559 bits (1440), Expect = e-159
 Identities = 321/543 (59%), Positives = 371/543 (68%), Gaps = 77/543 (14%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGG---SSSSYRAGGKGLSGGFSSRSLYSLGGARSI 57
           MSRQ T+      + GFSGCSAVLSGG   SS+S+RA  KG S  F S+SL  LGG+RS+
Sbjct: 1   MSRQLTHFP-RGERLGFSGCSAVLSGGIGSSSASFRARVKG-SASFGSKSLSCLGGSRSL 58

Query: 58  SFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPL 117
           + + A+  G         GR  GF G+ FGS  LG  CPS+CPPGGI QVT+NKSLLAPL
Sbjct: 59  ALSAAARRGG--------GRLGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPL 110

Query: 118 NVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKN 177
           NVE+DPEIQ+VRAQEREQIK LNNKFASFIDKVRFLEQQNQVLETKW LLQQLDLNNC+ 
Sbjct: 111 NVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRK 170

Query: 178 NLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFV 237
           NLEPI EGYISNL+KQLE LSGD VRLDSELR+++++VEDYKKRYE EIN+RT AENEFV
Sbjct: 171 NLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFV 230

Query: 238 VLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNL 297
           VLKKDVDAAY +KVELQAKVD+L  EIKFFKCLYEGE  QIQSHISDTSI+LSMDNNR+L
Sbjct: 231 VLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDL 290

Query: 298 DLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLI 357
           DLDSIIAEVRAQYEEIA KSKAEAE LYQTK  +L+ A                 +    
Sbjct: 291 DLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETA-----------------IADAE 333

Query: 358 QRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREY 417
           QR    ++  + +   LE A+  A+                         EELARMLREY
Sbjct: 334 QRGDCALKDARAKLDELEGALHQAK-------------------------EELARMLREY 368

Query: 418 QELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNA 477
           QEL+S+KL+LD+EIATYRKLLE EECRMSGEY NSVSISVI+S+ AG  G G   GF  +
Sbjct: 369 QELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFGAS 428

Query: 478 GTYGYWPSSVSGGYSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKK 537
            +Y Y  ++                       + +T+    SE +D   KT   S  TKK
Sbjct: 429 SSYSYKTAA----------------------ADVKTKGSCGSELKDPLAKTSGSSCATKK 466

Query: 538 TMR 540
             R
Sbjct: 467 ASR 469


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  559 bits (1440), Expect = e-159
 Identities = 299/550 (54%), Positives = 398/550 (72%), Gaps = 41/550 (7%)

Query: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSYR--------AGGKGLS------GGFSSR 46
           MSRQ +    + ++ GFS  SA+      S +         AG  GL         F SR
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSR 60

Query: 47  SLYSLGGARSISFNVASGS---GWAG----------GYGFGRGRASGFAGSMFGSVALGS 93
           SLY+LGGA+ +S N    S   G+ G          G+G+G G   GF+G  F       
Sbjct: 61  SLYNLGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSF------- 113

Query: 94  VCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFL 153
               +CPPGGI +VT+N+SLL PL++++DP IQ+VRA+EREQIK LNNKFASFIDKVRFL
Sbjct: 114 ---PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFL 170

Query: 154 EQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVRE 213
           EQQN+VLETKW LLQ+      + NLEP+ + Y S LR+QLE+++ +R RL++ELR++++
Sbjct: 171 EQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQD 230

Query: 214 VVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEG 273
           VVED+K RYE+EINKRT AENEFV LKKDVDAAY +KVEL+AKV +L  EI F   +++ 
Sbjct: 231 VVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDA 290

Query: 274 ETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQ 333
           E +Q+Q+ + DTS++LSMDNNRNLDLDSIIAEV+AQYE+IA +S+AEAE+ YQTK++ELQ
Sbjct: 291 ELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQ 350

Query: 334 LAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDAR 393
           + AGRHGDDL++TK EISE+ R+IQRLR+EI+SVKKQC++L+TAIADAEQRG+ ALKDAR
Sbjct: 351 VTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDAR 410

Query: 394 AKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSV 453
           AKL +LE ALQ+AK+++AR+LREYQEL+++KL+LD+EIATYRKLLEGEECR+SGE  + V
Sbjct: 411 AKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPV 470

Query: 454 SISVINSSMAGMAGTGAGFGFSNAGTYG--YWPSSVSGGYSMLPGGCVTGSGNCSPRGEA 511
           +ISV+ S+++   G+G+  G  N G  G   +  + SGG+S+  G  + GSG  +     
Sbjct: 471 NISVVTSTLSSGYGSGSSIGGGNLGLGGGSGYSFTTSGGHSL--GAGLGGSGFSATSNRG 528

Query: 512 RTRLGSASEF 521
               GS+ +F
Sbjct: 529 LGGSGSSVKF 538


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  551 bits (1420), Expect = e-157
 Identities = 302/535 (56%), Positives = 389/535 (72%), Gaps = 32/535 (5%)

Query: 1   MSRQFTYKSG--AAAKGGFSGCSAVLSGGSSSSYRA----------GGKGLSG-GFSSRS 47
           MS QF+ +S   + ++  +S  S+  SGG S +  +          GG G+ G GF SRS
Sbjct: 1   MSHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRS 60

Query: 48  LYSLGGARSISFNVASGS-----------GWAGGYGFGRGR--ASGFAGSMFGSVALGSV 94
           LY+LGG+RSIS N+   S           G+ GG GFG G   A GF G  FG    G+ 
Sbjct: 61  LYNLGGSRSISINLMGRSTSGFCQGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTS 120

Query: 95  CPSL------CPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFID 148
              L      CPPGGI +VTIN+SLL PL++E+DPEIQ+++ QEREQI VLNNKFASFID
Sbjct: 121 NFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFASFID 180

Query: 149 KVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSEL 208
           KVRFLEQQNQVL+TKWELLQQ++ +   NNLEP+LE YI +LR+Q++ LS +++R ++E+
Sbjct: 181 KVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQNAEV 240

Query: 209 RSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFK 268
           RS+++VVEDYK +YE+EINKRT +EN+FVVLKKDVDAAY SKV+L+++VD L GE+ F K
Sbjct: 241 RSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVNFLK 300

Query: 269 CLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTK 328
            L+  E +Q+Q+HISDT++ILSMDNNR+LDLDSII  VR QYE IA++SK EAEALYQTK
Sbjct: 301 YLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALYQTK 360

Query: 329 FQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCA 388
           +QELQ+ AGRHGDDLK++K EI+EL R +QRL++EI +VKKQ   +++ I+DAE+RG+ A
Sbjct: 361 YQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERGEQA 420

Query: 389 LKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGE 448
           L+DA  KL +LE ALQQ+KEELAR+LR+YQ +L VKLSLD+EIATYR+LLEGEE RMSGE
Sbjct: 421 LQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRMSGE 480

Query: 449 YTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGYSMLPGGCVTGSG 503
             + VSISV NS ++   G G G  + + G  G       GG S   GG    SG
Sbjct: 481 LQSHVSISVQNSQVSVNGGAGGGGSYGSGGYGGGSGGGYGGGRSYRGGGARGRSG 535



 Score = 33.5 bits (75), Expect = 0.51
 Identities = 24/64 (37%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 27  GSSSSYRAGGKG--LSGGFSSRSLYSLGGARSISFNVASGSGWAGGYGFGRGRASGFAGS 84
           G   SY +GG G    GG+     Y  GGAR       SG G+  G G G G   G   S
Sbjct: 501 GGGGSYGSGGYGGGSGGGYGGGRSYRGGGARG-----RSGGGYGSGCGGGGGSYGGSGRS 555

Query: 85  MFGS 88
             GS
Sbjct: 556 GRGS 559


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  546 bits (1408), Expect = e-155
 Identities = 313/549 (57%), Positives = 390/549 (71%), Gaps = 53/549 (9%)

Query: 1   MSRQFTYKSGAAAKGG-----FSGCSAVLSGGSSSS---------YRAGGKGLSGG-FSS 45
           MS Q + KS     GG     FS  SAV+SGGS  S         +  GG G  GG F S
Sbjct: 1   MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS 60

Query: 46  RSLYSLGGARSISFNVASGSGW---AGGY-----GFGRGRA----SGFAGSMFGSVAL-- 91
           RSL  LGG +SIS +VA G G    AGG+     GFG G +    SGF+G  FG      
Sbjct: 61  RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG 120

Query: 92  ---------GSVCPSLCP--------PGGIHQVTINKSLLAPLNVELDPEIQKVRAQERE 134
                    G V     P        PGGIH+V++N+SLL PLNV++DPEIQ V+AQERE
Sbjct: 121 GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE 180

Query: 135 QIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQL 194
           QIK LNNKFASFIDKVRFLEQQNQVL+TKWELLQQ+++     NLEPI +GYI +L++ L
Sbjct: 181 QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL 240

Query: 195 ETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQ 254
           + L+ +R   +SEL +++++VEDYKK+YE+EINKRT AEN+FV LKKDVD AY  KVELQ
Sbjct: 241 DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ 300

Query: 255 AKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIA 314
           +KVD L+ EI+F K LY+ E +QI   ++DT++ILSMDN+RNLDLDSIIAEV+AQYEEIA
Sbjct: 301 SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA 360

Query: 315 RKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANL 374
           ++SK EAEALY +K++ELQ+  GRHGD LK  K EISEL R+IQRL+ EI  VKKQC N+
Sbjct: 361 QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV 420

Query: 375 ETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATY 434
           + AIADAEQRG+ ALKDAR KL++LE ALQQAKE+LAR+LR+YQEL++VKL+LD+EIATY
Sbjct: 421 QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY 480

Query: 435 RKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGYSML 494
           RKLLEGEECRMSG+ +++V++SV +S+++    + A FG S     G   SS  GGYS  
Sbjct: 481 RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGS-----GGRGSSSGGGYS-- 533

Query: 495 PGGCVTGSG 503
            G    GSG
Sbjct: 534 SGSSSYGSG 542



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 32/89 (35%), Positives = 37/89 (41%), Gaps = 3/89 (3%)

Query: 3   RQFTYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVA 62
           RQ   + G+   G  SG      GGS   Y +GG    G  S     S GG  S      
Sbjct: 544 RQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSR 603

Query: 63  SGSGWAGGYGFGRGRAS---GFAGSMFGS 88
            GS   GGYG G G +S   G +G  FGS
Sbjct: 604 GGSSSGGGYGSGGGGSSSVKGSSGEAFGS 632



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 35/92 (38%), Positives = 41/92 (44%), Gaps = 16/92 (17%)

Query: 6   TYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGS 65
           T  S  A+K  F G     SGG  SS    G G S G SS   Y  GG +S S   + G 
Sbjct: 507 TISSNVASKAAFGG-----SGGRGSS---SGGGYSSGSSS---YGSGGRQSGSRGGSGGG 555

Query: 66  GWAGGYGFGRGRASG-----FAGSMFGSVALG 92
           G   G G+G G  SG       GS  GS++ G
Sbjct: 556 GSISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 33/90 (36%), Positives = 41/90 (45%), Gaps = 11/90 (12%)

Query: 10  GAAAKGGFS-GCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSG-- 66
           G+++ GG+S G S+  SGG  S    G +G SGG  S S    G          SG G  
Sbjct: 525 GSSSGGGYSSGSSSYGSGGRQS----GSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSK 580

Query: 67  ----WAGGYGFGRGRASGFAGSMFGSVALG 92
                 GGYG G G+ S   GS  GS + G
Sbjct: 581 GGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 24/67 (35%), Positives = 27/67 (40%), Gaps = 3/67 (4%)

Query: 7   YKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSG 66
           Y SG  +KGG        SGG   S    G G  GG SS   Y  GG  S S   +SG  
Sbjct: 573 YGSGGGSKGGSISGGGYGSGGGKHS---SGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEA 629

Query: 67  WAGGYGF 73
           +     F
Sbjct: 630 FGSSVTF 636


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  538 bits (1385), Expect = e-153
 Identities = 291/501 (58%), Positives = 370/501 (73%), Gaps = 18/501 (3%)

Query: 9   SGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGS--G 66
           SG+ A+  FS  +   S GS      G    +GGF SRSLY+LGG +SIS +VA G+  G
Sbjct: 25  SGSQARTSFSSVTVSRSSGSGGGAHCGPG--TGGFGSRSLYNLGGHKSISVSVAGGALLG 82

Query: 67  WA-GGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEI 125
            A GG+GFG   +  F G   G    G  CP    PGGI +VT+N+SLL PL+VE+DPEI
Sbjct: 83  RALGGFGFG---SRAFMGQGAGRQTFGPACP----PGGIQEVTVNQSLLTPLHVEIDPEI 135

Query: 126 QKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQL--DLNNCKNNLEPIL 183
           Q+VR QEREQIK LNNKFASFIDKVRFLEQQN+VLETKW LLQ+   +L   +NNLEP+ 
Sbjct: 136 QRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLF 195

Query: 184 EGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDV 243
           E Y+ ++R  L+ L  +R RLDSELR+V+++VED+K +YE+EINK T AENEFVVLKKDV
Sbjct: 196 EAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDV 255

Query: 244 DAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSII 303
           DAAY  +++L  KV  L  EI F + LYE E +Q+Q+H+S+T+++LSMDNNRNLDLDSII
Sbjct: 256 DAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSII 315

Query: 304 AEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSE 363
           AEV+AQYE IA++S+AEAEA YQTK++ELQ+ AG+HGD+L+ TKNEI+ELTR IQRL+ E
Sbjct: 316 AEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGE 375

Query: 364 IESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSV 423
            ++ KKQC  L+TAIA+AEQRG+ ALKDA+ KL +L+ AL QAKE+L R+LR+YQEL++V
Sbjct: 376 ADAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNV 435

Query: 424 KLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSM----AGMAGTGAGFGFSNAGT 479
           KL+LD+EIATYRKLLE EE RMSGE  ++VSISV  +S      G A  G G     +G 
Sbjct: 436 KLALDVEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGG 495

Query: 480 YGYWPSSVSGGYSMLPGGCVT 500
                 S + GYS + GG V+
Sbjct: 496 ATKGGFSTNVGYSTVKGGPVS 516


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  482 bits (1240), Expect = e-136
 Identities = 277/511 (54%), Positives = 346/511 (67%), Gaps = 25/511 (4%)

Query: 9   SGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWA 68
           S   A+ GFS  SA  +     S   GG    GGFSSRSL S GG    S     GS W 
Sbjct: 4   SPCRAQRGFSARSACSARSRGRS--RGGFSSRGGFSSRSLNSFGGCLEGS----RGSTWG 57

Query: 69  GGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKV 128
            G         G  G  FG  + G    SLCPPGGI +VTIN++LL PL +E+DP+ Q V
Sbjct: 58  SG---------GRLGVRFGEWS-GGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVV 107

Query: 129 RAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYIS 188
           R QE ++I+ LNN+FASFIDKVRFLEQQN+VLETKW LLQQ  L+  +  LEP+ E  + 
Sbjct: 108 RTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLD 167

Query: 189 NLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYT 248
            LRKQLE L G+R  LD+EL++ R+  E+YK +YEEE ++R T EN+FVVLKKDVD  + 
Sbjct: 168 QLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFL 227

Query: 249 SKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRA 308
           SK+EL+ K++AL   + F K L E E  Q+Q+  SDTS++LSMDNNR LD  SII EVRA
Sbjct: 228 SKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRA 287

Query: 309 QYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVK 368
           +YEEIAR SKAEAEALYQTK+QELQ++A  HGD ++ TK +IS+L + IQRL+S+ E++K
Sbjct: 288 RYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLK 347

Query: 369 KQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLD 428
           KQ A+L+ AI DAEQRG+ ALKDA+AK+DELE AL+ AK+ LAR+L EYQEL S KLSLD
Sbjct: 348 KQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLD 407

Query: 429 IEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVS 488
           +EIATYR+LLEGEECRMSGE T+ V+IS +  S     G G G G S  G      S  S
Sbjct: 408 VEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLG-STCGLGSGKGSPGS 466

Query: 489 GGYSMLPGG--CVTGSG------NCSPRGEA 511
              S++ GG   + GSG      +CS  G +
Sbjct: 467 CCTSIVTGGSNIILGSGKDPVLDSCSVSGSS 497


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  473 bits (1216), Expect = e-133
 Identities = 259/442 (58%), Positives = 329/442 (74%), Gaps = 17/442 (3%)

Query: 43  FSSRSLYSLGGARSISFNVA--SGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCP 100
           F+SRS    G    +  + A   G G +  YG G  R      S +G            P
Sbjct: 10  FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGG-----------P 58

Query: 101 PG-GIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQV 159
            G GI +VTIN+SLLAPL ++ DP +Q+VR +E EQIK LNNKFASFIDKVRFLEQQN++
Sbjct: 59  VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKL 118

Query: 160 LETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYK 219
           LETKW LLQ+   +   + L  I E  I+ LR QLE L  D  RL++ELRS+++VVED+K
Sbjct: 119 LETKWTLLQE-QKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFK 177

Query: 220 KRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQ 279
            +YE+EIN RT AENEFVVLKKDVDAAY SKVEL+AKVDAL+ EI F + L E E  ++Q
Sbjct: 178 NKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQ 237

Query: 280 SHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRH 339
           S ISDTS++LSMDN+R+LDLD IIAEV+AQYEE+A+ S+AEAEA YQTKF+ LQ  AG+H
Sbjct: 238 SQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKH 297

Query: 340 GDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDEL 399
           GDDL++T+NEISE+ R IQRL++EI+++K Q A LE AIA+AE+RG+ ALKDARAK +EL
Sbjct: 298 GDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEEL 357

Query: 400 EGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVIN 459
           E ALQ+ K+++AR LREYQEL+SVKL+LDIEIATYRKLLEGEE R++G+   +V+ISV+N
Sbjct: 358 EAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMN 417

Query: 460 SSMAGMAGTGAGFGFSNAGTYG 481
           S+  G + +G G G +  GT G
Sbjct: 418 ST--GGSSSGGGIGLTLGGTMG 437


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  463 bits (1191), Expect = e-130
 Identities = 270/511 (52%), Positives = 354/511 (69%), Gaps = 43/511 (8%)

Query: 28  SSSSYRAGGKGLSGGFSSRSLYSLGGAR--SISFNVASGSGWAGGYGFGRGRASGFAGSM 85
           +  SY+    G    FSSRS  S  G+R  S SF+    S + GG G G G ASG     
Sbjct: 6   TQKSYKVSTSG-PRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM---- 60

Query: 86  FGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFAS 145
                           GGI  VT+N+SLL+PL +E+DP IQ VR QE+EQIK LNNKFAS
Sbjct: 61  ----------------GGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFAS 104

Query: 146 FIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLD 205
           FIDKVRFLEQQN++LETKW LLQQ      ++N++ + E YI+NLR+QLETL  ++++L+
Sbjct: 105 FIDKVRFLEQQNKMLETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLE 162

Query: 206 SELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIK 265
           +EL +++ +VED+K +YE+EINKRT  ENEFV++KKDVD AY +KVEL+++++ L  EI 
Sbjct: 163 AELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEIN 222

Query: 266 FFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALY 325
           F + LYE E  ++QS ISDTS++LSMDN+R+LD+DSIIAEV+AQYE+IA +S+AEAE++Y
Sbjct: 223 FLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMY 282

Query: 326 QTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRG 385
           Q K++ELQ  AG+HGDDL+ TK EISE+ R I RL++EIE +K Q A+LE AIADAEQRG
Sbjct: 283 QIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRG 342

Query: 386 DCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRM 445
           + A+KDA AKL ELE ALQ+AK+++AR LREYQEL++VKL+LDIEIATYRKLLEGEE R+
Sbjct: 343 ELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRL 402

Query: 446 SGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPS---SVSGGYSMLPGGCVTGS 502
                N   +S+   + +G AG     G S+A  YG   S   S S G S    G   GS
Sbjct: 403 ESGMQN---MSIHTKTTSGYAG-----GLSSA--YGGLTSPGLSYSLGSSF---GSGAGS 449

Query: 503 GNCSPRGEARTRLGSASEFRDSQGKTLALSS 533
            + S    +R  +    E RD  GK ++ SS
Sbjct: 450 SSFSRTSSSRAVVVKKIETRD--GKLVSESS 478


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  439 bits (1130), Expect = e-123
 Identities = 257/500 (51%), Positives = 333/500 (66%), Gaps = 46/500 (9%)

Query: 3   RQFTYKSGAAAKGGFSGCSAV-------LSGGSSSSYRAGGKGLSGGFSSRSLYSLG--- 52
           R +   SG    G FS CSA+           S S +   G    G F SRS+ + G   
Sbjct: 4   RSYRVSSGHRV-GNFSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYS 62

Query: 53  ------GARSISFNVASGSGWAGGYGFGRG-----RAS---------------GFAGSMF 86
                 G+R I   V  G+G   G+G GRG     RA                GF G  F
Sbjct: 63  PRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGF 122

Query: 87  GSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASF 146
           G   +G V     P   I  VT+NKSLL PLN+E+DP  Q+V+  E+EQIK LNNKFASF
Sbjct: 123 G-YRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASF 179

Query: 147 IDKVRFLEQQNQVLETKWELLQQLDLNNC-KNNLEPILEGYISNLRKQLETLSGDRVRLD 205
           IDKVRFLEQQN++LETKW  LQ+     C ++NLEP+ E YI+NLR+QLE L  D+ RL 
Sbjct: 180 IDKVRFLEQQNKLLETKWSFLQE---QKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQ 236

Query: 206 SELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIK 265
           +E   +++V+E +KK+YEEE+  R  AENEFV LKKDVDAA+ +K +L+A VD L  EI 
Sbjct: 237 AERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEID 296

Query: 266 FFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALY 325
           F K LY  E   +QSHIS+TS+I+ MDN+R+L+LD IIAEV+AQYEE+AR+S+A+AEA Y
Sbjct: 297 FLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWY 356

Query: 326 QTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRG 385
           QTK++E+Q+ AG+H D+L++ +NEI+ELTRLIQRL++EIE  K Q A LE A+A+AEQ+G
Sbjct: 357 QTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQG 416

Query: 386 DCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRM 445
           +  L DA+ KL +LE ALQQAK+++AR L EYQEL++ KL LDIEIATYR+LLEGEE R+
Sbjct: 417 EATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRL 476

Query: 446 SGEYTNSVSISVINSSMAGM 465
             E    V+ISV +SS  G+
Sbjct: 477 C-EGVGPVNISV-SSSRGGL 494


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  422 bits (1084), Expect = e-118
 Identities = 250/519 (48%), Positives = 342/519 (65%), Gaps = 37/519 (7%)

Query: 3   RQFTYKSGAAAKGGFSGCSAVL--SGG----SSSSYRAGG--KGLSGGFSSRSLYSLGGA 54
           R +   SG      FS CSAV   +G     S++ YR     +GL+G F SRSL +LG  
Sbjct: 4   RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTG-FGSRSLCNLG-- 60

Query: 55  RSISFNVASGSGWAGGYGFGRGRASGFAGSMFGSVALGSVC-PSLCPPGGIHQVTINKSL 113
            S    +A G   AG  G   G  SG             VC PS   P  I  V++N+SL
Sbjct: 61  -SCGPRIAVGGFRAGSCGRSFGYRSG------------GVCGPS---PPCITTVSVNESL 104

Query: 114 LAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLN 173
           L PLN+E+DP  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETKW+  Q  +  
Sbjct: 105 LTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQR 162

Query: 174 NCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAE 233
            C++NLEP+  GYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE+  R TAE
Sbjct: 163 CCESNLEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAE 222

Query: 234 NEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDN 293
           NEFVVLKKDVD AY  K +L+A V+AL  E  F + LYE E   +Q+HISDTS+I+ MDN
Sbjct: 223 NEFVVLKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDN 282

Query: 294 NRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISEL 353
           +R+L++D IIAE++AQY+++A +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL
Sbjct: 283 SRDLNMDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINEL 342

Query: 354 TRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARM 413
            R+IQRL +EIE+ K Q A LE A+A+AEQ+G+ AL DAR KL ELEGALQ+AK+++A +
Sbjct: 343 NRMIQRLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACL 402

Query: 414 LREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFG 473
           L+EYQE+++ KL LDIEIATYR+LLEGEE R+  E   SV++ V +SS  G++  G  + 
Sbjct: 403 LKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCV-SSSRGGVSCGGLSYS 460

Query: 474 FSNAGTYGYWPSSVSGGYSML-PGGCVTGSGNCSPRGEA 511
            +        PS++ G  +++ P  C      C PR  +
Sbjct: 461 TTPGRQITSGPSAIGGSITVVAPDSCAP----CQPRSSS 495


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  416 bits (1069), Expect = e-116
 Identities = 248/499 (49%), Positives = 326/499 (65%), Gaps = 40/499 (8%)

Query: 52  GGARSISFNVASGSGWAGGYGFGRGR-ASGFAGSMFG-SVALGSVC-PSLCPPGGIHQVT 108
           GG R +      GS      GFGR R AS   G++ G    LG+ C PS C    I  VT
Sbjct: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSAC----ITPVT 96

Query: 109 INKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQ 168
           IN+SLL PL +E+DP +Q+V+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKW  +Q
Sbjct: 97  INESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQ 156

Query: 169 QLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINK 228
           Q     C+ N+EPI EGYIS LR+QL+ +SGDRVRL+SEL S++  +E YKK+YEEE++ 
Sbjct: 157 QQRC--CQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSL 214

Query: 229 RTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSII 288
           R   ENEFV LKKDVD A+  K +L+   +AL  EI F K LYE E   +QS IS+TS+I
Sbjct: 215 RPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVI 274

Query: 289 LSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKN 348
           + MDN+R LD+D IIAE++AQY++IA +SKAEAEA YQ +++EL++ AG H D+L++ KN
Sbjct: 275 VKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKN 334

Query: 349 EISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKE 408
           EI E+ +LIQRL+ E E+VK Q   LE AIA+AEQ+G+ AL DA+ KL  LE ALQ+AK+
Sbjct: 335 EILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQ 394

Query: 409 ELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGT 468
           ++A +L+EYQE+++ KL LDIEIATYR+LLEGEE R+  E    V+ISV +S        
Sbjct: 395 DMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSK------- 446

Query: 469 GAGFGFSNAGTYGYWPSSV-----SGGYSMLPGGC-VTGSGN----CSPRGEARTRLGSA 518
                    G + Y P  V     S G     GGC + G+G     C P+G      G  
Sbjct: 447 ---------GAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRK 497

Query: 519 SEFRDSQGKTLALSSPTKK 537
           S      G     SSP+ K
Sbjct: 498 SSMTLGAGG----SSPSHK 512


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  400 bits (1029), Expect = e-111
 Identities = 223/459 (48%), Positives = 309/459 (67%), Gaps = 21/459 (4%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCI 274

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482
            KL LDIEIATYR+LLEGEE R+  E   +V++ V +S    + G     G         
Sbjct: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCGDLCVSG--------- 444

Query: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519
               V+G     P  G     +G C+P G+  T  G  S
Sbjct: 445 -SRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGS 482


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  400 bits (1027), Expect = e-111
 Identities = 223/459 (48%), Positives = 308/459 (67%), Gaps = 21/459 (4%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 101

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 102 PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 159

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
             GYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE+  R TAENEFV LKKD
Sbjct: 160 FAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKD 219

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 220 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCI 279

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           +AE++AQY++IA +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 280 VAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 339

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 340 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 399

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGY 482
            KL LDIEIATYR+LLEGEE R+  E   +V++ V +S    + G     G         
Sbjct: 400 SKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCGDLCVSG--------- 449

Query: 483 WPSSVSGGYSMLP--GGCVTGSGNCSPRGEARTRLGSAS 519
               V+G     P  G  V  +G C P G+  T  G  S
Sbjct: 450 -SRPVTGSVCSAPCNGNLVVSTGLCKPCGQLNTTCGGGS 487


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  396 bits (1018), Expect = e-110
 Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460
            KL LDIEIATYR+LLEGEE R+  E   SV++ V +S
Sbjct: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  396 bits (1018), Expect = e-110
 Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460
            KL LDIEIATYR+LLEGEE R+  E   SV++ V +S
Sbjct: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  396 bits (1018), Expect = e-110
 Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460
            KL LDIEIATYR+LLEGEE R+  E   SV++ V +S
Sbjct: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  396 bits (1018), Expect = e-110
 Identities = 211/398 (53%), Positives = 291/398 (73%), Gaps = 9/398 (2%)

Query: 66  GWAGGYGFGR---GRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELD 122
           G  GG+G      G  +G  G  FG  + G   PS   P  I  V++N+SLL PLN+E+D
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPS---PPCITTVSVNESLLTPLNLEID 96

Query: 123 PEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPI 182
           P  Q V+ +E+EQIK LN++FA+FIDKVRFLEQQN++LETK +  Q  +   C++NLEP+
Sbjct: 97  PNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNREC--CQSNLEPL 154

Query: 183 LEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKD 242
            EGYI  LR++ E +  D  RL SEL  V+EV+E YKK+YEEE++ R TAENEFV LKKD
Sbjct: 155 FEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKD 214

Query: 243 VDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSI 302
           VD AY  K +L+A V+AL  EI F + LYE E   +QSHISDTS+++ +DN+R+L++D I
Sbjct: 215 VDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCI 274

Query: 303 IAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRS 362
           IAE++AQY++I  +S+AEAE+ Y++K +E++    RHG+ L+ TK EI+EL R+IQRL +
Sbjct: 275 IAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTA 334

Query: 363 EIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLS 422
           E+E+ K Q + LE A+A +EQ+G+ AL DAR KL ELEGALQ+AK+++A ++REYQE+++
Sbjct: 335 EVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMN 394

Query: 423 VKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINS 460
            KL LDIEIATYR+LLEGEE R+  E   SV++ V +S
Sbjct: 395 SKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.130    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,683,028
Number of Sequences: 37866
Number of extensions: 874777
Number of successful extensions: 7569
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 234
Number of HSP's successfully gapped in prelim test: 562
Number of HSP's that attempted gapping in prelim test: 4239
Number of HSP's gapped (non-prelim): 2413
length of query: 540
length of database: 18,247,518
effective HSP length: 107
effective length of query: 433
effective length of database: 14,195,856
effective search space: 6146805648
effective search space used: 6146805648
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.