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Search of human proteins with 27754773
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
(1237 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 2463 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 2046 0.0
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 1093 0.0
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 969 0.0
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 967 0.0
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 748 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 738 0.0
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 694 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 692 0.0
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 690 0.0
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 662 0.0
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 660 0.0
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 654 0.0
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 654 0.0
gi|190194360 protocadherin 20 [Homo sapiens] 436 e-122
gi|94538350 protocadherin 17 precursor [Homo sapiens] 353 6e-97
gi|16933557 dachsous 1 precursor [Homo sapiens] 348 1e-95
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 343 4e-94
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 342 1e-93
gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precurs... 342 1e-93
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 340 5e-93
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 340 5e-93
gi|11036656 protocadherin beta 7 precursor [Homo sapiens] 340 6e-93
gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precurs... 338 1e-92
gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precurs... 338 1e-92
gi|9256604 protocadherin beta 11 precursor [Homo sapiens] 338 2e-92
gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precurs... 334 4e-91
gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precurs... 334 4e-91
gi|9256606 protocadherin beta 12 precursor [Homo sapiens] 333 8e-91
gi|9256610 protocadherin beta 15 precursor [Homo sapiens] 333 8e-91
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 2463 bits (6383), Expect = 0.0
Identities = 1237/1237 (100%), Positives = 1237/1237 (100%)
Query: 1 MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV 60
MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV
Sbjct: 1 MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV 60
Query: 61 VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL 120
VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL
Sbjct: 61 VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL 120
Query: 121 RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN 180
RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN
Sbjct: 121 RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN 180
Query: 181 TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR 240
TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR
Sbjct: 181 TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR 240
Query: 241 ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI 300
ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI
Sbjct: 241 ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI 300
Query: 301 QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK 360
QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK
Sbjct: 301 QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK 360
Query: 361 DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS 420
DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS
Sbjct: 361 DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS 420
Query: 421 DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD 480
DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD
Sbjct: 421 DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD 480
Query: 481 SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE 540
SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE
Sbjct: 481 SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE 540
Query: 541 LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV 600
LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV
Sbjct: 541 LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV 600
Query: 601 NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI 660
NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI
Sbjct: 601 NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI 660
Query: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 720
QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN
Sbjct: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 720
Query: 721 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI 780
TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI
Sbjct: 721 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI 780
Query: 781 ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG 840
ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG
Sbjct: 781 ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG 840
Query: 841 DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK 900
DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK
Sbjct: 841 DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK 900
Query: 901 PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP 960
PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP
Sbjct: 901 PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP 960
Query: 961 GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY 1020
GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY
Sbjct: 961 GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY 1020
Query: 1021 SYRTNPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLG 1080
SYRTNPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLG
Sbjct: 1021 SYRTNPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLG 1080
Query: 1081 PLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSS 1140
PLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSS
Sbjct: 1081 PLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSS 1140
Query: 1141 PSRRTKSSALKLSTFVPYQDRGGQEPAGAGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHD 1200
PSRRTKSSALKLSTFVPYQDRGGQEPAGAGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHD
Sbjct: 1141 PSRRTKSSALKLSTFVPYQDRGGQEPAGAGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHD 1200
Query: 1201 SCKDSATLEEIPLTQTSDFPPAATPASAQTAKREIYL 1237
SCKDSATLEEIPLTQTSDFPPAATPASAQTAKREIYL
Sbjct: 1201 SCKDSATLEEIPLTQTSDFPPAATPASAQTAKREIYL 1237
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 2046 bits (5300), Expect = 0.0
Identities = 1033/1034 (99%), Positives = 1034/1034 (100%)
Query: 1 MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV 60
MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV
Sbjct: 1 MDSGAGGRRCPEAALLILGPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATRV 60
Query: 61 VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL 120
VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL
Sbjct: 61 VYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGL 120
Query: 121 RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN 180
RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN
Sbjct: 121 RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPEN 180
Query: 181 TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR 240
TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR
Sbjct: 181 TNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDR 240
Query: 241 ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI 300
ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI
Sbjct: 241 ERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVI 300
Query: 301 QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK 360
QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK
Sbjct: 301 QVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAK 360
Query: 361 DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS 420
DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS
Sbjct: 361 DRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS 420
Query: 421 DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD 480
DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD
Sbjct: 421 DRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVD 480
Query: 481 SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE 540
SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE
Sbjct: 481 SGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAE 540
Query: 541 LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV 600
LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV
Sbjct: 541 LVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLV 600
Query: 601 NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI 660
NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI
Sbjct: 601 NVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVI 660
Query: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 720
QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN
Sbjct: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSN 720
Query: 721 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI 780
TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI
Sbjct: 721 TSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI 780
Query: 781 ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG 840
ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG
Sbjct: 781 ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAG 840
Query: 841 DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK 900
DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK
Sbjct: 841 DPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPK 900
Query: 901 PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP 960
PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP
Sbjct: 901 PSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPP 960
Query: 961 GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY 1020
GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY
Sbjct: 961 GSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY 1020
Query: 1021 SYRTNPPKYPSKQL 1034
SYRTNPPKYPSKQ+
Sbjct: 1021 SYRTNPPKYPSKQV 1034
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 1093 bits (2827), Expect = 0.0
Identities = 605/1209 (50%), Positives = 804/1209 (66%), Gaps = 44/1209 (3%)
Query: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
Query: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
Query: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVA 222
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P G
Sbjct: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
Query: 223 EDQEEKQPQLIVMGN--------LDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTN 274
+ P GN + R D+ + GG+ P S++ + V DT
Sbjct: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASE-----GGGGTNPGGRSSVFELQVADTP 252
Query: 275 DNAPK---FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLR 331
D + + YEA+L+ENS G ++Q++A D D G N +IEY F A E VRRLLR
Sbjct: 253 DGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLR 312
Query: 332 LDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRG 391
LD +G ++V +DRE+++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR
Sbjct: 313 LDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRK 372
Query: 392 IGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GS 450
IG + +DG+AN++EDV +T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G
Sbjct: 373 IGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGD 432
Query: 451 DSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSV 510
+KKKYFL T+TPLDYE +++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV
Sbjct: 433 QNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSV 492
Query: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
EV FPENN PGE +A + A+DADSG NAE+ YSL + + G+F I P++G+I V T L
Sbjct: 493 VEVYFPENNIPGERVATVLATDADSGKNAEIAYSL--DSSVMGIFAIDPDSGDILVNTVL 550
Query: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
DREQ + YE KV A D+G P LQG+ TV+V V D NDNDPKFM + F V EN+ SP
Sbjct: 551 DREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSP 610
Query: 631 VGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDG 690
VGMVTV+D DKG NA++ L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDG
Sbjct: 611 VGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDG 670
Query: 691 GVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNA 750
G PPRSA V++ V+DENDNAP +T P N S+ LL P + + V+ V A D D G+NA
Sbjct: 671 GDPPRSATATVSLFVMDENDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINA 730
Query: 751 ELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
+L YSI GGNP+ LF+I SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH+
Sbjct: 731 DLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHV 790
Query: 811 YVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIAL 870
+VNE+++N T +++ + SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I +
Sbjct: 791 FVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILI 850
Query: 871 AVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDE 930
V+ RYCR + K+GY+AGKK+ +D + P+ K+ K K K K KS +P+ E
Sbjct: 851 VVMARYCRSKN-KNGYEAGKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVE 908
Query: 931 AGLQKSLKFNLMSDAPGDSPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSAS 988
A +++ +++ DSP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A
Sbjct: 909 ASKPNGQRYDSVNEKLSDSPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAG 968
Query: 989 KKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQLPHRRVTFSATSQAQ 1048
KKHQ VQDLPPANTFVG GD S GS+ S+YS +TN KY SKQ P RRVTFS SQ Q
Sbjct: 969 KKHQAVQDLPPANTFVGAGDNISIGSDHCSEYSCQTN-NKY-SKQ-PFRRVTFSVVSQPQ 1025
Query: 1049 ELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHYERTTPDGSIGEMEHPENDL 1108
+ S S YDSGLEESETPSSKSSSGPRLG L LPED+YERTTPDGS+ D
Sbjct: 1026 DPHQGSLQSCYDSGLEESETPSSKSSSGPRLGALPLPEDNYERTTPDGSV--------DS 1077
Query: 1109 RPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSRRTKSSALKLSTFVPYQDRGGQEPAG 1168
RPLPDVA+TG CTREC E+GHSD+CWMP ++SP R K S KLSTF+P +RG QE
Sbjct: 1078 RPLPDVALTGKCTRECDEYGHSDSCWMPVRTSPER--KKSQPKLSTFMPVDERGSQEKLA 1135
Query: 1169 AGSPSPPEDRNTKTAPVRLLPSYSAFSHSSHDSCKDSATLEEIPLTQTSDFPPAATPASA 1228
G + DRN +L SY FS +S S + A E+IPLT+T ++ P +P +
Sbjct: 1136 NGEAAIMGDRNRNLLNKKLTSSYETFSAASF-SKNEEANPEDIPLTKTGEYKP--SPVNT 1192
Query: 1229 QTAKREIYL 1237
T +RE+YL
Sbjct: 1193 LT-RREVYL 1200
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 969 bits (2504), Expect = 0.0
Identities = 522/1054 (49%), Positives = 706/1054 (66%), Gaps = 65/1054 (6%)
Query: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
Query: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
Query: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P
Sbjct: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
Query: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229
+A E +F LQVA+ + EKQ
Sbjct: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257
Query: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289
PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L
Sbjct: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
Query: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349
+ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+
Sbjct: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377
Query: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409
++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV
Sbjct: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437
Query: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468
+T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE
Sbjct: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497
Query: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528
+++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A +
Sbjct: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557
Query: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588
A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G
Sbjct: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615
Query: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648
P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++
Sbjct: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675
Query: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708
L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE
Sbjct: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735
Query: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768
NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I
Sbjct: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795
Query: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828
SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ +
Sbjct: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
Query: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888
SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A
Sbjct: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914
Query: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948
GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D
Sbjct: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973
Query: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006
SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG
Sbjct: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQLPHRRVT 1040
GD S GS+ S+YS +TN KY + H +T
Sbjct: 1034 GDNISIGSDHCSEYSCQTN-NKYSKQMRLHPYIT 1066
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 967 bits (2500), Expect = 0.0
Identities = 523/1048 (49%), Positives = 706/1048 (67%), Gaps = 66/1048 (6%)
Query: 46 LLLLLAPSPGHATRVV-YKVPEEQPPNTLIGSLAADYGF-PDVGHL-YKLEVGAPYLRVD 102
LLL L+ S A +++ Y++ EE P + IG++A+D G G + + LE G+ YL++D
Sbjct: 19 LLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGIVTGSGEVTFSLESGSEYLKID 78
Query: 103 GKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDIN 162
TG++ T+E IDRE L +CQ + C L+FEVS+ Q+ L EGQ+ V DIN
Sbjct: 79 NLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQSWVD-LFEGQVIVLDIN 137
Query: 163 DNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGP----------- 211
DNTP F SPV+TL + EN +G+L+ +P A+DRD G NG+ YEL P
Sbjct: 138 DNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYELLQEPGGGGSGGESRR 197
Query: 212 -----------------------------EAQE------------LFGLQVAEDQE-EKQ 229
+A E +F LQVA+ + EKQ
Sbjct: 198 AGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRSSVFELQVADTPDGEKQ 257
Query: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAEL 289
PQLIV G LDRE+ DSY+LT++V+DGG PPR+S A+LRV + D NDN+P+FE+ YEA+L
Sbjct: 258 PQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDVNDNSPRFEKSVYEADL 317
Query: 290 SENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRED 349
+ENS G ++Q++A D D G N +IEY F A E VRRLLRLD +G ++V +DRE+
Sbjct: 318 AENSAPGTPILQLRAADLDVGVNGQIEYVFGAATESVRRLLRLDETSGWLSVLHRIDREE 377
Query: 350 LSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVA 409
++ LRF+V+A+DRG PK+ +A VV+ +KD NDN P+IEIR IG + +DG+AN++EDV
Sbjct: 378 VNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVL 437
Query: 410 EETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET-GSDSKKKYFLQTTTPLDYEK 468
+T +ALVQVSDRD+GEN VTC V GDVPFQL+ AS+T G +KKKYFL T+TPLDYE
Sbjct: 438 VDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEA 497
Query: 469 VKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEI 528
+++ + IVAVDSG+P LSS NSL V+V D NDN P+F QSV EV FPENN PGE +A +
Sbjct: 498 TREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATV 557
Query: 529 TASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRG 588
A+DADSG NAE+ YSL+ + G+F I P++G+I V T LDREQ + YE KV A D+G
Sbjct: 558 LATDADSGKNAEIAYSLDS--SVMGIFAIDPDSGDILVNTVLDREQTDRYEFKVNAKDKG 615
Query: 589 SPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQ 648
P LQG+ TV+V V D NDNDPKFM + F V EN+ SPVGMVTV+D DKG NA++
Sbjct: 616 IPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGMVTVMDADKGRNAEMS 675
Query: 649 LSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDE 708
L +E++N F I+N TGTI S++SFDRE Q+TYTF++KAVDGG PPRSA V++ V+DE
Sbjct: 676 LYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDPPRSATATVSLFVMDE 735
Query: 709 NDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIG 768
NDNAP +T P N S+ LL P + + V+ V A D D G+NA+L YSI GGNP+ LF+I
Sbjct: 736 NDNAPTVTLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADLNYSIVGGNPFKLFEID 795
Query: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGH 828
SG ++L ++ ++H+GLHRLVV+V+D G+P + T LVH++VNE+++N T +++ +
Sbjct: 796 PTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQPSQSTTTLVHVFVNESVSNATAIDSQIAR 855
Query: 829 SLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQA 888
SL PL DIAGDP YE SKQR +I+ GVVAG++ V L+I + V+ RYCR + K+GY+A
Sbjct: 856 SLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIVVMARYCRSKN-KNGYEA 914
Query: 889 GKKETKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAPGD 948
GKK+ +D + P+ K+ K K K K KS +P+ EA +++ +++ D
Sbjct: 915 GKKDHEDFFTPQQHDKSKKPKKDK-KNKKSKQPLYSSIVTVEASKPNGQRYDSVNEKLSD 973
Query: 949 SPRI--HLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT 1006
SP + + +N PGSPDL RHY+S+SPLP++QL PQSP+A KKHQ VQDLPPANTFVG
Sbjct: 974 SPSMGRYRSVNGGPGSPDLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGA 1033
Query: 1007 GDTTSTGSEQYSDYSYRTNPPKYPSKQL 1034
GD S GS+ S+YS +TN KY SKQ+
Sbjct: 1034 GDNISIGSDHCSEYSCQTN-NKY-SKQV 1059
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 748 bits (1931), Expect = 0.0
Identities = 472/1165 (40%), Positives = 656/1165 (56%), Gaps = 86/1165 (7%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH--------LYKL- 92
+L AL+ L A ++Y + EE P N IG++ D + +Y+L
Sbjct: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
Query: 93 -EVG-APYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPR 150
+ G AP ++V TG+IFTT IDRE L + + C E EV I + N R
Sbjct: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVI---LPNDFFR 124
Query: 151 LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAG 210
L++ +I V+D NDN P F SPVI ++IPENT I S FPIP A+D D G NGV YEL G
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
Query: 211 PEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVT 269
Q +FGL + E E EK PQLIV NLDRE+ D+Y + IKV+DGG+P ++S+A+L+VT
Sbjct: 185 ---QSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
Query: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFH-QAPEVVRR 328
V D NDN P F+ E + EN+P+G SVIQ+ A D+D G+NAEI Y F Q +R
Sbjct: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
Query: 329 LLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIE 388
L L+ TGLITVQ +DRE+ + + +VLA D + P ARA V + V D+NDN P I+
Sbjct: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNID 359
Query: 389 IRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
+R I ++ +G +SE T +AL+ VSD+D N V C + +VPF L+ +
Sbjct: 360 LRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDN 417
Query: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQ 508
+Y L+T++ LDYE K+++ +IVA DSG P L+ T ++V++ D NDN P+F Q
Sbjct: 418 ------QYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ 471
Query: 509 SVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKT 568
V E++ ENN+ G + I+A+D DSG NA++VY L P + F + +TG +
Sbjct: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASR 528
Query: 569 SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL 628
DRE++E + V A D G+P LQ A V+V VLD NDN PKF + + F V EN+P
Sbjct: 529 VFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKY 588
Query: 629 SPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAV 688
S VG++TV D D GEN V LS+ DN +FV+ +G I S++SFDREQQS+YTF +KA
Sbjct: 589 STVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT 648
Query: 689 DGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSG 747
DGG PPRS+ VTINV+D NDN+P I+ PSNTS KL+ G V++V A D D+G
Sbjct: 649 DGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTG 708
Query: 748 VNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGT-A 806
+NAEL Y+I GN GLF+I +G ITLE++ GLHRLVV +SD G P T
Sbjct: 709 MNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLV 768
Query: 807 LVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVAL 866
LV LYVN+T N + + L+ +++TPLD +I + +++ I+ ++AG + V +
Sbjct: 769 LVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIV 828
Query: 867 LIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKP----- 921
+I + VLVR CR S ++A ++ + P+ + + K K KK KSPK
Sbjct: 829 VIFVTVLVR-CRH---ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNF 884
Query: 922 VKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHL-------PLNYPPGSPDLGRHYRSNSP 974
V E + + + + + + A + I P + P SPDL +HY+S SP
Sbjct: 885 VTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASP 944
Query: 975 LPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY----------SYRT 1024
P+ L+P +P + KKH V+Q+LP NTFVG DT S S SD+ ++T
Sbjct: 945 QPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKT 1004
Query: 1025 NPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLAL 1084
P + + RRVTF L D SQ S DSGL + E S + L PL
Sbjct: 1005 KGPLHTRQS--QRRVTF-------HLPDGSQESCSDSGLGDHEPVGSGTLISHPL-PLVQ 1054
Query: 1085 PEDHY-------ERTTPDGSIGEMEHPEND--LRPLPDVAMTGTCTRECSEFGHSDTCWM 1135
P+D + +RT DG+ P +D L P T CT+EC GHSD CWM
Sbjct: 1055 PQDEFYDQASPDKRTEADGN----SDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWM 1110
Query: 1136 PGQSSPSRRTKSSALKLSTFVPYQD 1160
P P + KS LSTF P ++
Sbjct: 1111 PPGLGPYQHPKS---PLSTFAPQKE 1132
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 738 bits (1905), Expect = 0.0
Identities = 476/1197 (39%), Positives = 658/1197 (54%), Gaps = 116/1197 (9%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH--------LYKL- 92
+L AL+ L A ++Y + EE P N IG++ D + +Y+L
Sbjct: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
Query: 93 -EVG-APYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPR 150
+ G AP ++V TG+IFTT IDRE L + + C E EV I + N R
Sbjct: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVI---LPNDFFR 124
Query: 151 LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAG 210
L++ +I V+D NDN P F SPVI ++IPENT I S FPIP A+D D G NGV YEL G
Sbjct: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
Query: 211 PEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVT 269
Q +FGL + E E EK PQLIV NLDRE+ D+Y + IKV+DGG+P ++S+A+L+VT
Sbjct: 185 ---QSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
Query: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFH-QAPEVVRR 328
V D NDN P F+ E + EN+P+G SVIQ+ A D+D G+NAEI Y F Q +R
Sbjct: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
Query: 329 LLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIE 388
L L+ TGLITVQ +DRE+ + + +VLA D + P ARA V + V D+NDN P I+
Sbjct: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNID 359
Query: 389 IRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
+R I ++ +G +SE T +AL+ VSD+D N V C + +VPF L+ +
Sbjct: 360 LRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDN 417
Query: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQ 508
+Y L+T++ LDYE K+++ +IVA DSG P L+ T ++V++ D NDN P+F Q
Sbjct: 418 ------QYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ 471
Query: 509 SVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKT 568
V E++ ENN+ G + I+A+D DSG NA++VY L P + F + +TG +
Sbjct: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASR 528
Query: 569 SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL 628
DRE++E + V A D G+P LQ A V+V VLD NDN PKF + + F V EN+P
Sbjct: 529 VFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKY 588
Query: 629 SPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAV 688
S VG++TV D D GEN V LS+ DN +FV+ +G I S++SFDREQQS+YTF +KA
Sbjct: 589 STVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT 648
Query: 689 DGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSG 747
DGG PPRS+ VTINV+D NDN+P I+ PSNTS KL+ G V++V A D D+G
Sbjct: 649 DGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTG 708
Query: 748 VNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGT-A 806
+NAEL Y+I GN GLF+I +G ITLE++ GLHRLVV +SD G P T
Sbjct: 709 MNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLV 768
Query: 807 LVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVAL 866
LV LYVN+T N + + L+ +++TPLD +I + +++ I+ ++AG + V +
Sbjct: 769 LVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIV 828
Query: 867 LIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKP----- 921
+I + VLVR CR S ++A ++ + P+ + + K K KK KSPK
Sbjct: 829 VIFVTVLVR-CRH---ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNF 884
Query: 922 VKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHL-------PLNYPPGSPDLGRHYRSNSP 974
V E + + + + + + A + I P + P SPDL +HY+S SP
Sbjct: 885 VTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASP 944
Query: 975 LPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY----------SYRT 1024
P+ L+P +P + KKH V+Q+LP NTFVG DT S S SD+ ++T
Sbjct: 945 QPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKT 1004
Query: 1025 --------------------NPPKYPSKQLPH------------RRVTFSATSQAQELQD 1052
P K PS H RRVTF L D
Sbjct: 1005 KGPLHTRQCNSHSKSDNIPVTPQKCPSSTGFHIQENEESHYESQRRVTF-------HLPD 1057
Query: 1053 PSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHY-------ERTTPDGSIGEMEHPE 1105
SQ S DSGL + E S + L PL P+D + +RT DG+ P
Sbjct: 1058 GSQESCSDSGLGDHEPVGSGTLISHPL-PLVQPQDEFYDQASPDKRTEADGN----SDPN 1112
Query: 1106 ND--LRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSRRTKSSALKLSTFVPYQD 1160
+D L P T CT+EC GHSD CWMP P + KS LSTF P ++
Sbjct: 1113 SDGPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKS---PLSTFAPQKE 1166
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 694 bits (1791), Expect = 0.0
Identities = 451/1186 (38%), Positives = 644/1186 (54%), Gaps = 99/1186 (8%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q K+ + + P P + K K KK K SPK
Sbjct: 822 ITVVVVIFITAVVR-CRQAPHLKAAQKNKQNS-EWATPNPENRQMIMMKKKKKKKKHSPK 879
Query: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTT---STGSEQYS-------- 1018
+S SP P+ Q+QP++P SK H ++Q+LP NTFV + S+ S+ YS
Sbjct: 940 KSASPQPAFQIQPETPLNSK-HHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPV 998
Query: 1019 -----DYSYRTNPPKY-------PSKQLPHRRVTFSATSQAQE-----LQDPSQHSYYDS 1061
S T PP P K+ + Q+Q L + SQ S D
Sbjct: 999 TTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQSQRRVTFHLPEGSQESSSDG 1058
Query: 1062 GLEESETPSSKSSSGPRLGPLALP-EDHYERTTP------DGSI--------GEMEHPEN 1106
GL + + S S+S PL P E++++R TP DG+ G + E
Sbjct: 1059 GLGDHDAGSLTSTSHGL--PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEI 1116
Query: 1107 DLRPLPDVAMTGTCTRECSEFGHSDTCWMPG--QSSPSRRTKSSAL 1150
++P + A + CT+EC +GHSD CWMP S S + ++SAL
Sbjct: 1117 TVQPTVEEA-SDNCTQECLIYGHSDACWMPASLDHSSSSQAQASAL 1161
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 692 bits (1785), Expect = 0.0
Identities = 448/1167 (38%), Positives = 642/1167 (55%), Gaps = 90/1167 (7%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL+ A Y + EE P N LIG+L D + +
Sbjct: 35 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 95 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 148
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 149 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 208
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 209 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 265
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 266 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 325
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 326 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 383
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+ LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 442 PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 495
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A+DADSG NAE+ Y L P+ + F++ TG
Sbjct: 496 PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 553
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + Y F V E
Sbjct: 554 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 613
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 614 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 673
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I P N S++L+ P T G V QV A
Sbjct: 674 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 733
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 734 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 793
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S++ P+ + + IL VAG
Sbjct: 794 LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 853
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q + + + P P + K K KK K SPK
Sbjct: 854 ITVVVVIFITAVVR-CRQAPHLKAAQKNMQNS-EWATPNPENRQMIMMKKKKKKKKHSPK 911
Query: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 912 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 971
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGT---GDTTSTGSEQYS--DYSYRT 1024
+S SP P+ Q+QP++P + KH ++Q+LP NTFV + +S+ S+ YS D Y
Sbjct: 972 KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYSVSDCGYPV 1030
Query: 1025 NPPKYPSK---QLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGP 1081
+ P + RRVTF L + SQ S D GL + + S S+S P
Sbjct: 1031 TTFEVPVSVHTRPSQRRVTF-------HLPEGSQESSSDGGLGDHDAGSLTSTSHGL--P 1081
Query: 1082 LALP-EDHYERTTP------DGSIGEMEHPENDLRP--------LPDVA-MTGTCTRECS 1125
L P E++++R TP DG+ PE+ P P V + CT+EC
Sbjct: 1082 LGYPQEEYFDRATPSNRTEGDGN----SDPESTFIPGLKKEITVQPTVEEASDNCTQECL 1137
Query: 1126 EFGHSDTCWMPG--QSSPSRRTKSSAL 1150
+GHSD CWMP S S + ++SAL
Sbjct: 1138 IYGHSDACWMPASLDHSSSSQAQASAL 1164
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 690 bits (1781), Expect = 0.0
Identities = 451/1196 (37%), Positives = 645/1196 (53%), Gaps = 109/1196 (9%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q K+ + P P + K K KK K SPK
Sbjct: 822 ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
Query: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFV---GTGDTTSTGSEQYS-------- 1018
+S SP P+ Q+QP++P + KH ++Q+LP NTFV +S+ S+ YS
Sbjct: 940 KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPV 998
Query: 1019 -----DYSYRTNPPK-------YPSKQ----------LPHRRVTFSATSQAQ-----ELQ 1051
S T PP P K+ P R+ ++Q L
Sbjct: 999 TTFEVPVSVHTRPPMKEVVRSCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLP 1058
Query: 1052 DPSQHSYYDSGLEESETPSSKSSSGPRLGPLALP-EDHYERTTP------DGSI------ 1098
+ SQ S D GL + + S S+S PL P E++++R TP DG+
Sbjct: 1059 EGSQESSSDGGLGDHDAGSLTSTSHGL--PLGYPQEEYFDRATPSNRTEGDGNSDPESTF 1116
Query: 1099 --GEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPG--QSSPSRRTKSSAL 1150
G + E ++P + A + CT+EC +GHSD CWMP S S + ++SAL
Sbjct: 1117 IPGLKKAAEITVQPTVEEA-SDNCTQECLIYGHSDACWMPASLDHSSSSQAQASAL 1171
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 662 bits (1707), Expect = 0.0
Identities = 408/1039 (39%), Positives = 580/1039 (55%), Gaps = 54/1039 (5%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q K+ + P P + K K KK K SPK
Sbjct: 822 ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
Query: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKY 1029
+S SP P+ Q+QP++P + KH ++Q+LP NTFV + S YS
Sbjct: 940 KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYSVSDCGYPV 998
Query: 1030 PSKQLP---HRRVTFSATS 1045
+ ++P H R T S TS
Sbjct: 999 TTFEVPVSVHTRPTDSRTS 1017
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 660 bits (1703), Expect = 0.0
Identities = 401/1012 (39%), Positives = 570/1012 (56%), Gaps = 51/1012 (5%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL A Y + EE P N LIG L D + +
Sbjct: 3 LLSGTYIFAVLLACVVFHSGAQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTAMQ 62
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 63 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 116
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 117 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 176
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 177 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 233
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 234 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 293
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 294 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 351
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 352 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 409
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+T LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 410 PVFSN------QFLLETAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 463
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A DADSG NA++ Y L P+ + F++ TG
Sbjct: 464 PVFTQSFVTVSIPENNSPGIQLTKVSAMDADSGPNAKINYLLGPDAPPE--FSLDCRTGM 521
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + YNF V E
Sbjct: 522 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPE 581
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 582 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 641
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I PSN S++L+ P T G V QV A
Sbjct: 642 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAV 701
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 702 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 761
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S + P+ + + IL VAG
Sbjct: 762 LFSVVIVNLFVNESVTNATLINELVRKSTEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 821
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q K+ + P P + K K KK K SPK
Sbjct: 822 ITVVVVIFITAVVR-CRQAPHLKAAQK-NKQNSEWATPNPENRQMIMMKKKKKKKKHSPK 879
Query: 921 PV---------KPVEDEDEAG--LQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
+ +D D G + L +L G + P + P SPDL RHY
Sbjct: 880 NLLLNFVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 939
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
+S SP P+ Q+QP++P + KH ++Q+LP NTFV + S YS
Sbjct: 940 KSASPQPAFQIQPETP-LNSKHHIIQELPLDNTFVACDSISKCSSSSSDPYS 990
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1012 (39%), Positives = 571/1012 (56%), Gaps = 51/1012 (5%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL+ A Y + EE P N LIG+L D + +
Sbjct: 35 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 94
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 95 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 148
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 149 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 208
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 209 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 265
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 266 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 325
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 326 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 383
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 384 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 441
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+ LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 442 PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 495
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A+DADSG NAE+ Y L P+ + F++ TG
Sbjct: 496 PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 553
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + Y F V E
Sbjct: 554 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 613
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 614 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 673
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I P N S++L+ P T G V QV A
Sbjct: 674 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 733
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 734 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 793
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S++ P+ + + IL VAG
Sbjct: 794 LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 853
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q + + P P + K K KK K SPK
Sbjct: 854 ITVVVVIFITAVVR-CRQAPHLKAAQK-NMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 911
Query: 921 ----PVKPVE-------DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
V +E D D + L +L G + P + P SPDL RHY
Sbjct: 912 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 971
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
+S SP P+ Q+QP++P + KH ++Q+LP NTFV ++ S YS
Sbjct: 972 KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYS 1022
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 654 bits (1687), Expect = 0.0
Identities = 399/1012 (39%), Positives = 571/1012 (56%), Gaps = 51/1012 (5%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH-------- 88
LL + + A+LL+ A Y + EE P N LIG+L D + +
Sbjct: 24 LLSGTYIFAVLLVCVVFHSGAQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQ 83
Query: 89 ---LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
+YK P +R++ TG+IFTT IDRE L C + C E EV+I +
Sbjct: 84 FKLVYKTG-DVPLIRIEEDTGEIFTTGARIDREKL--CAGIPRDEHCFYEVEVAI---LP 137
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ RL++ + ++DINDN P F + VI ++IPEN+ I S + +P A D D G NGV +Y
Sbjct: 138 DEIFRLVKIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNY 197
Query: 206 ELQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSA 264
EL ++Q +FGL V E E +K PQLIV LDRE D+Y + +KV+DGG P R+S+A
Sbjct: 198 ELI---KSQNIFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTA 254
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-AP 323
+L+V+V DTNDN P F+ E + EN+P+G SV Q+ A D+D G NA+I ++F
Sbjct: 255 ILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVS 314
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ RRL L+ TGLIT++ P+DRE+ + VLA D G P ARA V+V V D+NDN
Sbjct: 315 NIARRLFHLNATTGLITIKEPLDREETPNHKLLVLASDGGLMP--ARAMVLVNVTDVNDN 372
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P+I+IR I V + +SE++ T +AL+ V+D+D N VTC ++PF+LR
Sbjct: 373 VPSIDIRYI--VNPVNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLR 430
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++ L+ LDYE K+Y I+++A D+G PPL+ + L ++V D NDNA
Sbjct: 431 PVFSN------QFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNA 484
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
PVFTQS V+ PENN PG + +++A+DADSG NAE+ Y L P+ + F++ TG
Sbjct: 485 PVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPDAPPE--FSLDRRTGM 542
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ V LDRE+ + Y ++A D G P L TV V+++D NDN P F + Y F V E
Sbjct: 543 LTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPE 602
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
N+P VG++TV D D G+N+ V LS+ +N DF I + TG I ++SFDRE+Q +YTF
Sbjct: 603 NLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTF 662
Query: 684 QLKAVDGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAE 742
+KA DGG RS+ VTINV+D NDN P +I P N S++L+ P T G V QV A
Sbjct: 663 YVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAV 722
Query: 743 DFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPR 802
D D+G+NAE+ YSI GGN LF I +G ITL ++ + GLHR++VK +D G+P
Sbjct: 723 DNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDS 782
Query: 803 -YGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGV 861
+ +V+L+VNE++ N TL+ L+ S++ P+ + + IL VAG
Sbjct: 783 LFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTSDYVKILVAAVAGT 842
Query: 862 VAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSK-SPK 920
+ V ++I + +VR CRQ Q + + P P + K K KK K SPK
Sbjct: 843 ITVVVVIFITAVVR-CRQAPHLKAAQK-NMQNSEWATPNPENRQMIMMKKKKKKKKHSPK 900
Query: 921 ----PVKPVE-------DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHY 969
V +E D D + L +L G + P + P SPDL RHY
Sbjct: 901 NLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTFKPDSPDLARHY 960
Query: 970 RSNSPLPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYS 1021
+S SP P+ Q+QP++P + KH ++Q+LP NTFV ++ S YS
Sbjct: 961 KSASPQPAFQIQPETP-LNLKHHIIQELPLDNTFVACDSISNCSSSSSDPYS 1011
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 436 bits (1120), Expect = e-122
Identities = 300/854 (35%), Positives = 438/854 (51%), Gaps = 68/854 (7%)
Query: 21 PRMEHLR-HSPGPGGQRLLLPSMLLALLLL----LAPSPGHATRVVYKVPEEQPPNTLIG 75
PR++ R H P LP + L L + S AT ++Y + E P LIG
Sbjct: 24 PRLDMGRLHRPRSSTSYRNLPHLFLFFLFVGPFSCLGSYSRATELLYSLNEGLPAGVLIG 83
Query: 76 SLAADY-------GFPDVGHLYKLEVGAP-----------------YLRVDGKTGDIFTT 111
SLA D G PD GA Y+ +D ++G++ T+
Sbjct: 84 SLAEDLRLLPRSAGRPDPQSQLPERTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTS 143
Query: 112 ETSIDREGL------------RECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQ 159
IDRE L + P D C+L +V + + R ++ +I ++
Sbjct: 144 AQEIDREALCVEGGGGTAWSGSVSISSSPSDSCLLLLDVLV---LPQEYFRFVKVKIAIR 200
Query: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPL-ASDRDAGPNGVASYELQAGPEAQELFG 218
DINDN P F I++ +PEN + + I A D D G NGV +Y L + +F
Sbjct: 201 DINDNAPQFPVSQISVWVPENAPVNTRLAIEHPAVDPDVGINGVQTYRLL---DYHGMFT 257
Query: 219 LQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNA 277
L V E++ E+ P LIVMG LDRE D Y I +DGGSPP SA L + + D NDN
Sbjct: 258 LDVEENENGERTPYLIVMGALDRETQDQYVSIIIAEDGGSPPLLGSATLTIGISDINDNC 317
Query: 278 PKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-APEVVRRLLRLDRNT 336
P F + N+ +G + V+A D D G NA+I Y++ Q P+ + L LD NT
Sbjct: 318 PLFTDSQINVTVYGNATVGTPIAAVQAVDKDLGTNAQITYSYSQKVPQASKDLFHLDENT 377
Query: 337 GLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
G+I + + L + + ++LA G P A +V++ + P I R I
Sbjct: 378 GVIKLFSKIGGSVLESHKLTILANGPGCIPAVITA--LVSIIKVIFRPPEIVPRYIA--N 433
Query: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
DG+ + E T +A + RD V C + G+ PF+L ++ Y
Sbjct: 434 EIDGVVYLKELEPVNTPIAFFTI--RDPEGKYKVNCYLDGEGPFRLSPYKPYNNE----Y 487
Query: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
L+TT P+DYE + Y + +VA +S + +KVQ++D NDNAP+F Q + E+
Sbjct: 488 LLETTKPMDYELQQFYEVAVVAWNSEGFHVKRV--IKVQLLDDNDNAPIFLQPLIELTIE 545
Query: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
ENN P + ++ A+DADS ++ Y L P+ A F++ TG + V T LDRE++E
Sbjct: 546 ENNSPNAFLTKLYATDADSEERGQVSYFLGPD--APSYFSLDSVTGILTVSTQLDREEKE 603
Query: 577 SYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTV 636
Y V A D G P + ATV + VLD NDN P+F+ ++F V EN P +G+++V
Sbjct: 604 KYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKDFSFFVPENFPGYGEIGVISV 663
Query: 637 IDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRS 696
D D G N V LSV + FVI G G + + +S DREQQS+YT ++AVDGG P S
Sbjct: 664 TDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDREQQSSYTLWVEAVDGGEPALS 723
Query: 697 AYVGVTINVLDENDNAPYITAP-SNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYS 755
+ +TI +LD NDN P + P SN S+ L+ P T G V++V A D D+G+NA + YS
Sbjct: 724 STAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSPVTEVYAVDKDTGMNAVIAYS 783
Query: 756 IAG--GNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP-PRYGTALVHLYV 812
I G G F+I +G ITLE+ + + +GLHRL+VKVSD G P P + T +V+L+V
Sbjct: 784 IIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVKVSDHGYPEPLHSTVMVNLFV 843
Query: 813 NETLANRTLLETLL 826
N+T++N + +E+LL
Sbjct: 844 NDTVSNESYIESLL 857
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 353 bits (906), Expect = 6e-97
Identities = 245/686 (35%), Positives = 351/686 (51%), Gaps = 71/686 (10%)
Query: 62 YKVPEEQPPNTLIGSLAADY----GFPDV----------GHLYKLEVGAPYLR-VDGKTG 106
Y VPEEQ T+IG++ D G P G LE AP+L VD +G
Sbjct: 23 YSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAPHLLDVDADSG 82
Query: 107 DIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTP 166
++T + IDRE L C++ C L EV D + ++E+QDINDN P
Sbjct: 83 LLYTKQR-IDRESL--CRHNAK---CQLSLEVFAND------KEICMIKVEIQDINDNAP 130
Query: 167 NFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQV-AEDQ 225
+F+S I + I EN G+ FP+ A D DAG NG+ +Y L LFGL V +
Sbjct: 131 SFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHG--LFGLDVKSRGD 188
Query: 226 EEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSY 285
K P+L++ LDRE+ + + L + DGG PPR+++ + V V+D+NDN+P FE PSY
Sbjct: 189 GTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPSY 248
Query: 286 EAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-APEVVRRLLRLDRNTGLITVQGP 344
EL EN+P+G VI + A D+D+G N E+ Y+F P+ VR L +D TGLI V+G
Sbjct: 249 LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKGN 308
Query: 345 VDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANI 404
+D E+ L V A+D G NP A +V V + D NDNAP+ IG V+ + G +
Sbjct: 309 LDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPS-----IGFVSVRQGA--L 361
Query: 405 SEDVAEETAVALVQVSDRDEGENAAVTCVV---------------AGDVPFQLRQASETG 449
SE T +ALV+V+DRD G+N + C V G VPF+L +
Sbjct: 362 SEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEE----- 416
Query: 450 SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQS 509
+ Y + T PLD E +Y + IVA D G+PPL+ST S ++++D NDN P FT+
Sbjct: 417 -NYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKG 475
Query: 510 VTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEP----EPAAKGLFTISPETGEIQ 565
+ + ENN PGE + + A D D G N + YS+ P + + +++P G I
Sbjct: 476 LYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIY 535
Query: 566 VKTSLDREQRESYELKVVAADRGSPS-LQGTATVLVNVLDCNDNDPKFMLSGYNFSVME- 623
S + EQ +++E KV+A D G+P+ L+ ATV V VLD NDN P +L E
Sbjct: 536 ALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAEL 595
Query: 624 NMPALSPVG----MVTVIDGDKGENAQVQLSVEQDNGD--FVIQNGTGTILSSLSFDREQ 677
+P + +G V +D D GE+ ++ + N D F I +G I + F +
Sbjct: 596 QVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDV 655
Query: 678 QSTYTFQLKAVDGGVPPRSAYVGVTI 703
+K D G P SA + I
Sbjct: 656 TPVVELVVKVTDHGKPTLSAVAKLII 681
Score = 238 bits (607), Expect = 3e-62
Identities = 245/926 (26%), Positives = 381/926 (41%), Gaps = 99/926 (10%)
Query: 265 LLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPE 324
+++V + D NDNAP F E ++SEN+ G A+D D G N Y +
Sbjct: 117 MIKVEIQDINDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDH 176
Query: 325 VVRRLLRLDRNTGL----ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDM 380
+ L R G + +Q +DRE + + A D G P+SA Q+ V V D
Sbjct: 177 GLFGLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDS 236
Query: 381 NDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPF 440
NDN+P E + + E+ T V + +D DEG N V + VP
Sbjct: 237 NDNSPVFEAPSY--------LVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPD 288
Query: 441 QLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVN 500
++R E S K ++ LDYE+ I++ A D G P+ + + V+++D N
Sbjct: 289 RVR---ELFSIDPKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRN 345
Query: 501 DNAP-VFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISP 559
DNAP + SV + A E PG VIA + +D DSG N +L + G +
Sbjct: 346 DNAPSIGFVSVRQGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGG 405
Query: 560 ETGEIQVKTS--------------LDREQRESYELKVVAADRGSPSLQGTATVLVNVLDC 605
G + K LDRE ++ Y + +VA D GSP L T + + +LD
Sbjct: 406 PGGSVPFKLEENYDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDE 465
Query: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDN-GD-----FV 659
NDN P+F Y V EN +G V D D G+N V S+ + GD +V
Sbjct: 466 NDNPPRFTKGLYVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYV 525
Query: 660 IQNGT-GTILSSLSFDREQQSTYTFQLKAVDGGVPPR-SAYVGVTINVLDENDNAPYITA 717
N T G I + SF+ EQ + F++ A D G P + V + VLD NDNAP I
Sbjct: 526 SVNPTNGAIYALRSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVL 585
Query: 718 PS--NTSHKLLTPQTR-LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAI 774
P+ N + +L P+ LG VS V A D D G + L Y I GN LF+I SG I
Sbjct: 586 PTLQNDTAELQVPRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEI 645
Query: 775 TLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPL 834
+ LVVKV+D GKP A + ++ ++ G +
Sbjct: 646 RTLHPFWEDVTPVVELVVKVTDHGKPTLSAVA------------KLIIRSVSGSLPE--- 690
Query: 835 DIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETK 894
G P + ++ ++ + +++++ A++ + + +
Sbjct: 691 -----GVPRVNGEQHHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENKEIRTYNCRIA 745
Query: 895 DLYAPKPSGKASKGNKSKGKKSKSPKPVKPVEDEDEAGLQKSLKFNLMSDAP-GDSPRIH 953
+ P+ G KG K K K+ VE+ + + + ++ +P +
Sbjct: 746 EYSHPQLGG--GKGKKKKINKNDIMLVQSEVEERNAMNVMNVVSSPSLATSPMYFDYQTR 803
Query: 954 LPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPSASKKHQVVQDLPPANT-FVGTGDTTST 1012
LPL+ P + L+P AS V Q +T F G G S
Sbjct: 804 LPLSSPRSE--------------VMYLKP----ASNNLTVPQGHAGCHTSFTGQGTNASE 845
Query: 1013 GSEQYSDYSYRTNPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEES-ETPSS 1071
N P P+ ++ S+++ +DP + S DSG +S + S
Sbjct: 846 TPATRMSIIQTDNFPAEPNYMGSRQQFVQSSST----FKDPERASLRDSGHGDSDQADSD 901
Query: 1072 KSSSGPRLGPLALPEDHYERTTPDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSD 1131
+ ++ +++ E +TT S + PE + CT EC GHSD
Sbjct: 902 QDTNKGSCCDMSVREALKMKTTSTKSQPLEQEPEECV----------NCTDECRVLGHSD 951
Query: 1132 TCWMPGQSSPSRRTKSSALKLSTFVP 1157
CWMP Q + + +++ + + FVP
Sbjct: 952 RCWMP-QFPAANQAENADYRTNLFVP 976
Score = 189 bits (481), Expect = 1e-47
Identities = 155/520 (29%), Positives = 228/520 (43%), Gaps = 56/520 (10%)
Query: 329 LLRLDRNTGLITVQGPVDREDLST------LRFSVLAKDRGTNPKSARAQVVVTVKDMND 382
LL +D ++GL+ + +DRE L L V A D+ + V ++D+ND
Sbjct: 74 LLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEI------CMIKVEIQDIND 127
Query: 383 NAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQL 442
NAP+ I + +ISE+ A T L D D GEN T ++ D
Sbjct: 128 NAPSFSSDQIEM--------DISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLF 179
Query: 443 RQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDN 502
++ D K L LD E+ +T+ + A+D G PP S+T + V+V+D NDN
Sbjct: 180 GLDVKSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDN 239
Query: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEP--EPAAKGLFTISPE 560
+PVF V PEN G V+ ++ A+DAD G N E++YS + LF+I P+
Sbjct: 240 SPVFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPK 299
Query: 561 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKF-MLSGYNF 619
TG I+VK +LD E+ E+ V A D G + V V ++D NDN P +S
Sbjct: 300 TGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVRQG 359
Query: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD--------------FVIQNGTG 665
++ E P + + +V V D D G+N Q+Q V G F ++
Sbjct: 360 ALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYD 419
Query: 666 ---TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTS 722
T+++ DRE Q Y + A DGG PP ++ I +LDENDN P T
Sbjct: 420 NFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFT---KGL 476
Query: 723 HKLLTPQTRL-GETVSQVAAEDFDSGVNAELIYSIAGG-----NPYGLFQIGSHSGAITL 776
+ L + + GE + V A+D D G N + YSI + Y + +GAI
Sbjct: 477 YVLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYA 536
Query: 777 EKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETL 816
+ V D G P HL N T+
Sbjct: 537 LRSFNFEQTKAFEFKVLAKDSGAP-------AHLESNATV 569
Score = 113 bits (283), Expect = 1e-24
Identities = 95/327 (29%), Positives = 136/327 (41%), Gaps = 37/327 (11%)
Query: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEP--------------- 547
AP T + PE G VI I G +A L L P
Sbjct: 13 APALTLKNLNYSVPEEQGAGTVIGNI-------GRDARLQPGLPPAERGGGGRSKSGSYR 65
Query: 548 --EPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDC 605
E +A L + ++G + K +DRE + K + + + + V + D
Sbjct: 66 VLENSAPHLLDVDADSGLLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDI 125
Query: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENA-QVQLSVEQDNGDF---VIQ 661
NDN P F + EN + + + D D GEN + L D+G F V
Sbjct: 126 NDNAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKS 185
Query: 662 NGTGTILSSL----SFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITA 717
G GT L + DREQQ+ +T L A+DGG PPRSA V + + V+D NDN+P A
Sbjct: 186 RGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEA 245
Query: 718 PSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNP---YGLFQIGSHSGAI 774
PS L LG V + A D D G N E++YS + P LF I +G I
Sbjct: 246 PSYLVE--LPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLI 303
Query: 775 TLEKEIERRHHGLHRLVVKVSDRGKPP 801
++ ++ +G+ + V+ D G P
Sbjct: 304 RVKGNLDYEENGMLEIDVQARDLGPNP 330
>gi|16933557 dachsous 1 precursor [Homo sapiens]
Length = 3298
Score = 348 bits (894), Expect = 1e-95
Identities = 264/784 (33%), Positives = 379/784 (48%), Gaps = 47/784 (5%)
Query: 29 SPGPGGQRLLLPSMLLALLLLLAPSPG---HATRVVYKVPEEQPPNTLIGSLAADYGFPD 85
SP P LLLP +LL LLLL A PG A + ++ EEQP TLIG ++A G P
Sbjct: 16 SPRP---HLLLPLLLLLLLLLGAGVPGAWGQAGSLDLQIDEEQPAGTLIGDISA--GLP- 69
Query: 86 VGHLYKLEVGAPYLR-VDGKTGDIFTTETSIDRE-GLRECQNQLPGDPCILEFEVSITDL 143
AP + + + G T+ +ID G+ L + T +
Sbjct: 70 ------AGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTARVLDREQ---RDRYRFTAV 120
Query: 144 VQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVA 203
+G+ +E + V DIND+ P F L +PE+T G+ +P+ A D DAG G
Sbjct: 121 TPDGAT--VEVTVRVADINDHAPAFPQARAALQVPEHTAFGTRYPLEPARDADAGRLGTQ 178
Query: 204 SYELQAGPEAQELFGLQVAEDQEEKQ-PQLIVMGNLDRERWDSYDLTIKVQDGGSPPRAS 262
Y L +G A E F L+ + P+L+V G LDRE Y L ++ DGGSPPR +
Sbjct: 179 GYAL-SGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRSHYMLQLEAYDGGSPPRRA 237
Query: 263 SALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA 322
ALL VT+LD ND+AP F + Y A +SE+ G V+QV A+D+D G N + Y ++
Sbjct: 238 QALLDVTLLDINDHAPAFNQSRYHAVVSESLAPGSPVLQVFASDADAGVNGAVTYEINRR 297
Query: 323 PEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMND 382
+D +TGL+ ++ P+D E V A+D G +P+ A V V V+D ND
Sbjct: 298 QSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDGGAHPELGSAFVTVHVRDAND 357
Query: 383 NAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAV-TCVVAGDVPFQ 441
N P++ + + DG +SE VA + VSD D+G+ A V + G+ F
Sbjct: 358 NQPSMTV----IFLSADGSPQVSEAAPPGQLVARISVSDPDDGDFAHVNVSLEGGEGHFA 413
Query: 442 LRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
L + Y + LD E+ Y + + A DSG+PPL + + + V DVND
Sbjct: 414 L------STQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPPLRAEAAFVLHVTDVND 467
Query: 502 NAPVF-TQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE 560
NAP F Q PE PG + +TA D D G+N ++ YSL P A F+I P
Sbjct: 468 NAPAFDRQLYRPEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAP-GAHTHWFSIDPT 526
Query: 561 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 620
+G I SLD E +L VVA D G P L +ATV V + D NDN+P+F + YN S
Sbjct: 527 SGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQDVNDNEPQFQRTFYNAS 586
Query: 621 VMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-----FVIQNGTGTILSSLSFDR 675
+ E + VT D D G + S+ G F I +G + ++ + DR
Sbjct: 587 LPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRIDAHSGDVCTTRTLDR 646
Query: 676 EQ-QSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGE 734
+Q S++ F + AVDGG YV V ++ DENDN P + ++ Q+ G
Sbjct: 647 DQGPSSFDFTVTAVDGGGLKSMVYVKVFLS--DENDNPPQFYPREYAAS--ISAQSPPGT 702
Query: 735 TVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKV 794
V ++ A D D G + L Y I GN LF + SG +T+ + RR + + +L +
Sbjct: 703 AVLRLRAHDPDQGSHGRLSYHILAGNSPPLFTLDEQSGLLTVAWPLARRANSVVQLEIGA 762
Query: 795 SDRG 798
D G
Sbjct: 763 EDGG 766
Score = 255 bits (651), Expect = 2e-67
Identities = 276/1034 (26%), Positives = 422/1034 (40%), Gaps = 120/1034 (11%)
Query: 53 SPGHATRVVYKVPEEQPPN-TLIGSLAADYGFPDVGHL----YKLEVGAP-YLRVDGKTG 106
+P A+ ++PE+QPP + +A D PD+G Y+L G + R+ TG
Sbjct: 1543 APVFASPSRVRLPEDQPPGPAALHVVARD---PDLGEAARVSYRLASGGDGHFRLHSSTG 1599
Query: 107 DIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQI---EVQDIND 163
+ +DRE E V +GSP Q+ V D+ND
Sbjct: 1600 ALSVVRP-LDREQRAE--------------HVLTVVASDHGSPPRSATQVLTVSVADVND 1644
Query: 164 NTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAE 223
P F ++ + EN G+ A+D D G NG +Y G + E F L
Sbjct: 1645 EAPTFQQQEYSVLLRENNPPGTSLLTLRATDPDVGANGQVTY----GGVSSESFSL---- 1696
Query: 224 DQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERP 283
+ L + LDRE + +LT+ QD GSPP+ + +RV V D ND+AP F
Sbjct: 1697 --DPDTGVLTTLRALDREEQEEINLTVYAQDRGSPPQLTHVTVRVAVEDENDHAPTFGSA 1754
Query: 284 SYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQG 343
E+ E ++ ++A+D D GAN +++Y LD +G
Sbjct: 1755 HLSLEVPEGQD-PQTLTMLRASDPDVGANGQLQYRILDGDP--SGAFVLDLASGEFGTMR 1811
Query: 344 PVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMAN 403
P+DRE + + A+D G SA + VTV D ND+AP + +
Sbjct: 1812 PLDREVEPAFQLRIEARDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSV--------E 1863
Query: 404 ISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTP 463
+ EDV T + +Q D D G N VT + +G L+T
Sbjct: 1864 VPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLLEPSSGE-------LRTAAA 1916
Query: 464 LDYEKVKDYTIEIVAVDSGNP-PLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPEN---- 518
LD E+ YT + AVD PLS+T S+ + V DVND+AP F S + P
Sbjct: 1917 LDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLRLPRPGPSF 1976
Query: 519 NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESY 578
+ P +A + A D D+G+NA ++Y L P T+ TGEI+V S
Sbjct: 1977 STPTLALATLRAEDRDAGANASILYRLAGTPPPGT--TVDSYTGEIRVARSPVALGPRDR 2034
Query: 579 ELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVID 638
L +VA D G P+ T ++V + + P+F + ++ EN P +P+ +
Sbjct: 2035 VLFIVATDLGRPARSATGVIIVGLQGEAERGPRFPRASSEATIRENAPPGTPIVSPRAVH 2094
Query: 639 GDKGENAQVQLSVEQDN--GDFVIQNGTG--TILSSLSFDREQQSTYTFQLKAVDGGVPP 694
G N + S+ N G F IQ TG T+ S+ D E L+A GG
Sbjct: 2095 AG-GTNGPITYSILSGNEKGTFSIQPSTGAITVRSAEGLDFEVSPRLRLVLQAESGGA-- 2151
Query: 695 RSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTR-LGETVSQVAAEDFDSGVNAELI 753
A+ +T+ + D NDNAP P + P++R L + QV A+D D G ++
Sbjct: 2152 -FAFTVLTLTLQDANDNAPRFLRPHYVA---FLPESRPLEGPLLQVEADDLDQGSGGQIS 2207
Query: 754 YSIAGGNPY-GLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
YS+A P GLF + +G IT ++R RLV+ +DRG P G+A + + V
Sbjct: 2208 YSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVLMATDRGSPALVGSATLTVMV 2267
Query: 813 NETLANRTLL----------ETLLGHSLDTPLDIDIAGDP----EYERSKQRGNILFGVV 858
+T NR + + LLG + D+ P S + G
Sbjct: 2268 IDTNDNRPTIPQPWELRVSEDALLGSEIAQVTGNDVDSGPVLWYVLSPSGPQDPFSVGRY 2327
Query: 859 AGVVAVALLIALAVLVRYCRQREAKSGYQAGKKE----TKDLYAPKPSGKASKGNKSKGK 914
G V++ + RY Q A G G+ +D+ P+ S +
Sbjct: 2328 GGRVSLTGPLDFEQCDRYQLQLLAHDGPHEGRANLTVLVEDVNDNAPAFSQSLYQVMLLE 2387
Query: 915 KSKSPKPVKPVEDED-EAGLQKSLKFNLMSDAPGDSPRIH----------LPLNYPPG-- 961
+ + V D ++G + ++L S A G S + + L +
Sbjct: 2388 HTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGA 2447
Query: 962 ------SPDLGRHYRSNSPLPSIQLQPQ---SPSASKKH---QVVQDLPPANTFVGTGDT 1009
+ D G R+ +QLQ Q +PS + H V +DLPP +T + T
Sbjct: 2448 VDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEAT 2507
Query: 1010 TSTGSEQYS--DYS 1021
+ GS ++ DYS
Sbjct: 2508 DADGSRSHAAVDYS 2521
Score = 253 bits (645), Expect = 1e-66
Identities = 234/785 (29%), Positives = 347/785 (44%), Gaps = 84/785 (10%)
Query: 19 GPPRMEHLRHSPGPGGQRLLLPSMLLALLLLLAPSPGHATR-----VVYKVPEEQPPNTL 73
GPP + GPGG + LL + + + HA + +PE P
Sbjct: 1399 GPPWRALTVRAEGPGGAG----ARLLRVQVQVQDENEHAPAFARDPLALALPENPEPGAA 1454
Query: 74 IGSLAA---DYGFPDVGHLYKL---EVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQL 127
+ + A D P+ Y+L E P LR+D +TG + + +DRE
Sbjct: 1455 LYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGAL-SAPRGLDRETT------- 1506
Query: 128 PGDPCILEFEVSITDLVQNGSPRL---LEGQIEVQDINDNTPNFASPVITLAIPENTNIG 184
P +L V TD N S R + ++ V D NDN P FASP + +PE+ G
Sbjct: 1507 ---PALLLL-VEATDRPANASRRRAARVSARVFVTDENDNAPVFASPS-RVRLPEDQPPG 1561
Query: 185 SLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWD 244
+A D D G SY L +G + F L + L V+ LDRE+
Sbjct: 1562 PAALHVVARDPDLGEAARVSYRLASGGDGH--FRLHSSTGA------LSVVRPLDREQRA 1613
Query: 245 SYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKA 304
+ LT+ D GSPPR+++ +L V+V D ND AP F++ Y L EN+P G S++ ++A
Sbjct: 1614 EHVLTVVASDHGSPPRSATQVLTVSVADVNDEAPTFQQQEYSVLLRENNPPGTSLLTLRA 1673
Query: 305 NDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGT 364
D D GAN ++ Y V LD +TG++T +DRE+ + +V A+DRG+
Sbjct: 1674 TDPDVGANGQVTY-----GGVSSESFSLDPDTGVLTTLRALDREEQEEINLTVYAQDRGS 1728
Query: 365 NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAE---ETAVALVQVSD 421
P+ V V V+D ND+APT G A++S +V E + +++ SD
Sbjct: 1729 PPQLTHVTVRVAVEDENDHAPTF------------GSAHLSLEVPEGQDPQTLTMLRASD 1776
Query: 422 RDEGENAAVTCVVAGDVPFQLRQASETGS---DSKKKYFLQTTTPLDYEKVKDYTIEIVA 478
D G N G + +++ +G+ D F T PLD E + + I A
Sbjct: 1777 PDVGAN--------GQLQYRILDGDPSGAFVLDLASGEF-GTMRPLDREVEPAFQLRIEA 1827
Query: 479 VDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
D G P LS+T L V V+D ND+AP F V PE+ G ++ ++ A D D+G+N
Sbjct: 1828 RDGGQPALSATLLLTVTVLDANDHAPAFPVPAYSVEVPEDVPAGTLLLQLQAHDPDAGAN 1887
Query: 539 AELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPS-LQGTAT 597
+ Y L A G F + P +GE++ +LDREQ SY V A D + L T +
Sbjct: 1888 GHVTYYLGAGTA--GAFLLEPSSGELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVS 1945
Query: 598 VLVNVLDCNDNDPKFMLSGYNFSVMENMPALS----PVGMVTVIDGDKGENAQV--QLSV 651
V + V D ND+ P F S + P+ S + + D D G NA + +L+
Sbjct: 1946 VTITVRDVNDHAPTFPTSPLRLRLPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAG 2005
Query: 652 EQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDN 711
G + + TG I + S + A D G P RSA + + + E +
Sbjct: 2006 TPPPGT-TVDSYTGEIRVARSPVALGPRDRVLFIVATDLGRPARSATGVIIVGLQGEAER 2064
Query: 712 APYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHS 771
P P +S + G + A G N + YSI GN G F I +
Sbjct: 2065 GPRF--PRASSEATIRENAPPGTPIVSPRAV-HAGGTNGPITYSILSGNEKGTFSIQPST 2121
Query: 772 GAITL 776
GAIT+
Sbjct: 2122 GAITV 2126
Score = 242 bits (618), Expect = 1e-63
Identities = 245/878 (27%), Positives = 380/878 (43%), Gaps = 133/878 (15%)
Query: 90 YKLEVGAP---YLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQN 146
Y L P VD TG I TT +DRE E + L
Sbjct: 2208 YSLAASQPARGLFHVDPTTGTI-TTTAILDREIWAETRLVLMA--------------TDR 2252
Query: 147 GSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVA 203
GSP L+ + V D NDN P P L + E+ +GS +D D+GP V
Sbjct: 2253 GSPALVGSATLTVMVIDTNDNRPTIPQPW-ELRVSEDALLGSEIAQVTGNDVDSGP--VL 2309
Query: 204 SYELQ-AGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRAS 262
Y L +GP+ G ++ + G LD E+ D Y L + DG P
Sbjct: 2310 WYVLSPSGPQDPFSVGRYGG--------RVSLTGPLDFEQCDRYQLQLLAHDG---PHEG 2358
Query: 263 SALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQA 322
A L V V D NDNAP F + Y+ L E++P G +++ V A D D GAN I Y
Sbjct: 2359 RANLTVLVEDVNDNAPAFSQSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLASP 2418
Query: 323 PEVVRRLLRLDRNTG-LITVQGPV--DREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKD 379
+ +D N G L T+ G V + + + A+D G ++ARA V V ++D
Sbjct: 2419 ADG----FSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQD 2474
Query: 380 MNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVT--CVVAGD 437
ND+AP+ + + ++ED+ + + ++ +D D + A +++G+
Sbjct: 2475 QNDHAPSFTLSHYRVA--------VTEDLPPGSTLLTLEATDADGSRSHAAVDYSIISGN 2526
Query: 438 ------VPFQLRQASET-GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN 490
+ +L +A E+ G + L PLD+E + Y + + A D G PP SS
Sbjct: 2527 WGRVFQLEPRLAEAGESAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVV 2586
Query: 491 SLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA 550
+ V V+DVNDN PVFT++ V PE+ G + + ASDAD G + + +++
Sbjct: 2587 PVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRFTVSSGDP 2646
Query: 551 AKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDP 610
+ GLF + +G +++ +LD E + ++L V AAD A V + V D ND+ P
Sbjct: 2647 S-GLFELDESSGTLRLAHALDCETQARHQLVVQAADPAGAHF-ALAPVTIEVQDVNDHGP 2704
Query: 611 KFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSV------EQDNGDFVIQNGT 664
F L+ + SV EN P + V + IDGD G +++ S+ + F + + T
Sbjct: 2705 AFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGREAFALNSST 2764
Query: 665 GTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHK 724
G + + + FD E ++ + A D G SA V V++ V E++ P AP+ H
Sbjct: 2765 GELRARVPFDYEHTESFRLLVGAADAG--NLSASVTVSVLVTGEDEYDPVFLAPA--FHF 2820
Query: 725 LLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEI---- 780
+ R G ++ V A D D G + ++YS+A +PY F I +GA+ L +
Sbjct: 2821 QVPEGARRGHSLGHVQATDEDGGADGLVLYSLATSSPY--FGINQTTGALYLRVDSRAPG 2878
Query: 781 ----------ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSL 830
R L ++V RG P +A V + V+ T T LG +
Sbjct: 2879 SGTATSGGGGRTRREAPRELRLEVIARGPLPGSRSATVPVTVDIT-------HTALGLAP 2931
Query: 831 DTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVALLIALAVLVR---YCRQREAKSGYQ 887
D L +L G VA + V +++ALA LV R R+A++
Sbjct: 2932 DLNL------------------LLVGAVAASLGVVVVLALAALVLGLVRARSRKAEA--- 2970
Query: 888 AGKKETKDLYAPKPSGK----ASKGNKSKGKKSKSPKP 921
AP P + AS + G++ SP P
Sbjct: 2971 ----------APGPMSQAAPLASDSLQKLGREPPSPPP 2998
Score = 242 bits (617), Expect = 2e-63
Identities = 221/772 (28%), Positives = 337/772 (43%), Gaps = 62/772 (8%)
Query: 59 RVVYKVPEEQPPNTLIGSLAADYGF--PDVGH----LYKLEVGAP--YLRVDGKTGDIFT 110
R +Y+ PE P L GS PD G Y L GA + +D +G I T
Sbjct: 474 RQLYR-PEPLPEVALPGSFVVRVTARDPDQGTNGQVTYSLAPGAHTHWFSIDPTSG-IIT 531
Query: 111 TETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDINDNTPN 167
T S+D E E Q QL I G P L + +QD+NDN P
Sbjct: 532 TAASLDYE--LEPQPQL------------IVVATDGGLPPLASSATVSVALQDVNDNEPQ 577
Query: 168 FASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEE 227
F ++PE T G+ F A+D D+GP G+ SY L AG + ++ +
Sbjct: 578 FQRTFYNASLPEGTQPGTCFLQVTATDADSGPFGLLSYSLGAGLGSSGSPPFRI----DA 633
Query: 228 KQPQLIVMGNLDRERW-DSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYE 286
+ LDR++ S+D T+ DGG S ++V + D NDN P+F Y
Sbjct: 634 HSGDVCTTRTLDRDQGPSSFDFTVTAVDGGG--LKSMVYVKVFLSDENDNPPQFYPREYA 691
Query: 287 AELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVD 346
A +S SP G +V++++A+D DQG++ + Y H L LD +GL+TV P+
Sbjct: 692 ASISAQSPPGTAVLRLRAHDPDQGSHGRLSY--HILAGNSPPLFTLDEQSGLLTVAWPLA 749
Query: 347 REDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISE 406
R S ++ + A+D G A+V +++ P E + ++ E
Sbjct: 750 RRANSVVQLEIGAEDGGGLQAEPSARVDISIVPGTPTPPIFE--------QLQYVFSVPE 801
Query: 407 DVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDY 466
DVA T+V +VQ + G A VT ++G P L LQT PLD
Sbjct: 802 DVAPGTSVGIVQAHN-PPGRLAPVTLSLSGGDPRGLFSLDAVSG------LLQTLRPLDR 854
Query: 467 EKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIA 526
E + V SG PP + ++V + DVNDN+P F V P N PG I
Sbjct: 855 ELLGPVLELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAPEDTVLLPPNTAPGTPIY 914
Query: 527 EITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAAD 586
+ A D DSG N+ + ++L G FT+ P TG +++ L ++EL++ A D
Sbjct: 915 TLRALDPDSGVNSRVTFTLLA--GGGGAFTVDPTTGHVRLMRPLGPSGGPAHELELEARD 972
Query: 587 RGSPSLQGTATVLVNVLDCNDND--PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGEN 644
GSP + V V D P+F Y + A + V V D G
Sbjct: 973 GGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGGP- 1031
Query: 645 AQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG---V 701
L+ E + F ++ +G + + DRE Q Y ++ AV G G V
Sbjct: 1032 ITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATV 1091
Query: 702 TINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAG-GN 760
+++L++N+++P ++ + + + G +V +V A D DSG N L YS+
Sbjct: 1092 RVSILNQNEHSPRLS--EDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSE 1149
Query: 761 PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
F+I +G +T + ++R ++L+V+V D G PPR T VH+ V
Sbjct: 1150 DSKAFRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAV 1201
Score = 227 bits (579), Expect = 5e-59
Identities = 207/695 (29%), Positives = 300/695 (43%), Gaps = 65/695 (9%)
Query: 134 LEFEVS-----ITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNI-GSLF 187
L+FEVS + G+ + +QD NDN P F P +PE+ + G L
Sbjct: 2132 LDFEVSPRLRLVLQAESGGAFAFTVLTLTLQDANDNAPRFLRPHYVAFLPESRPLEGPLL 2191
Query: 188 PIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYD 247
+ A D D G G SY L A A+ LF + + + LDRE W
Sbjct: 2192 QVE-ADDLDQGSGGQISYSLAASQPARGLFHV------DPTTGTITTTAILDREIWAETR 2244
Query: 248 LTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDS 307
L + D GSP SA L V V+DTNDN P +P +E +SE++ +G + QV ND
Sbjct: 2245 LVLMATDRGSPALVGSATLTVMVIDTNDNRPTIPQP-WELRVSEDALLGSEIAQVTGNDV 2303
Query: 308 DQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPK 367
D G + +P + + R G +++ GP+D E + +LA D P
Sbjct: 2304 DSGP----VLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHD---GPH 2356
Query: 368 SARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGEN 427
RA + V V+D+NDNAP + + E +A+ V +DRD G N
Sbjct: 2357 EGRANLTVLVEDVNDNAPAF--------SQSLYQVMLLEHTPPGSAILSVSATDRDSGAN 2408
Query: 428 AAVTCVVAGDVPFQLRQASETGSDSKKKYFLQT---TTPLDYEKVKDYTIEIVAVDSGNP 484
G + + L ++ S L T T L ++ + + A D G P
Sbjct: 2409 --------GHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAP 2460
Query: 485 PLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDAD-SGSNAELVY 543
++ ++ VQ+ D ND+AP FT S VA E+ PG + + A+DAD S S+A + Y
Sbjct: 2461 GRAARATVHVQLQDQNDHAPSFTLSHYRVAVTEDLPPGSTLLTLEATDADGSRSHAAVDY 2520
Query: 544 S-----------LEPEPAAKGLFTISP---ETGEIQVKTSLDREQRESYELKVVAADRGS 589
S LEP A G + P G + + LD E Y L V AADRG
Sbjct: 2521 SIISGNWGRVFQLEPRLAEAGE-SAGPGPRALGCLVLLEPLDFESLTQYNLTVAAADRGQ 2579
Query: 590 PSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQL 649
P V V VLD NDN P F + Y +V E+ P + + V D D G + V+
Sbjct: 2580 PPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVPEDTPVGAELLHVEASDADPGPHGLVRF 2639
Query: 650 SVE--QDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLD 707
+V +G F + +GT+ + + D E Q+ + ++A D A VTI V D
Sbjct: 2640 TVSSGDPSGLFELDESSGTLRLAHALDCETQARHQLVVQAAD-PAGAHFALAPVTIEVQD 2698
Query: 708 ENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSI--AGGNPYG-- 763
ND+ P P N + G V+ + A D D+G L YS+ AG P G
Sbjct: 2699 VNDHGP--AFPLNLLSTSVAENQPPGTLVTTLHAIDGDAGAFGRLRYSLLEAGPGPEGRE 2756
Query: 764 LFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRG 798
F + S +G + + H RL+V +D G
Sbjct: 2757 AFALNSSTGELRARVPFDYEHTESFRLLVGAADAG 2791
Score = 216 bits (551), Expect = 8e-56
Identities = 218/775 (28%), Positives = 331/775 (42%), Gaps = 59/775 (7%)
Query: 51 APSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFT 110
AP+ G A + +VPE Q P TL A+D PDVG +L+ Y +DG F
Sbjct: 1748 APTFGSA-HLSLEVPEGQDPQTLTMLRASD---PDVGANGQLQ----YRILDGDPSGAFV 1799
Query: 111 TETSIDREG-LRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFA 169
+ + G +R ++ +P + + D Q L + V D ND+ P F
Sbjct: 1800 LDLASGEFGTMRPLDREV--EPAF-QLRIEARDGGQPALSATLLLTVTVLDANDHAPAFP 1856
Query: 170 SPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQ 229
P ++ +PE+ G+L A D DAG NG +Y L AG L E
Sbjct: 1857 VPAYSVEVPEDVPAGTLLLQLQAHDPDAGANGHVTYYLGAGTAGAFLL--------EPSS 1908
Query: 230 PQLIVMGNLDRERWDSYDLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFERPSYEAE 288
+L LDRE+ SY ++ DG + P +++ + +TV D ND+AP F
Sbjct: 1909 GELRTAAALDREQCPSYTFSVSAVDGAAAGPLSTTVSVTITVRDVNDHAPTFPTSPLRLR 1968
Query: 289 LSENSPIGHS----VIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITV-QG 343
L P + + ++A D D GANA I Y P + D TG I V +
Sbjct: 1969 LPRPGPSFSTPTLALATLRAEDRDAGANASILYRLAGTPPPGTTV---DSYTGEIRVARS 2025
Query: 344 PVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMAN 403
PV + F ++A D G +SA ++V ++ + P A
Sbjct: 2026 PVALGPRDRVLF-IVATDLGRPARSATGVIIVGLQGEAERGPRFP--------RASSEAT 2076
Query: 404 ISEDVAEETAVALVQVSDRDEGENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTT 462
I E+ T + + G N +T +++G+ TG+ + +++
Sbjct: 2077 IRENAPPGTPIVSPRAVHAG-GTNGPITYSILSGNEKGTFSIQPSTGAIT-----VRSAE 2130
Query: 463 PLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPG 522
LD+E V ++ +SG + +L +Q D NDNAP F + PE+
Sbjct: 2131 GLDFE-VSPRLRLVLQAESGGAFAFTVLTLTLQ--DANDNAPRFLRPHYVAFLPESRPLE 2187
Query: 523 EVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKV 582
+ ++ A D D GS ++ YSL A+GLF + P TG I LDRE L +
Sbjct: 2188 GPLLQVEADDLDQGSGGQISYSLAASQPARGLFHVDPTTGTITTTAILDREIWAETRLVL 2247
Query: 583 VAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKG 642
+A DRGSP+L G+AT+ V V+D NDN P + + V E+ S + VT D D G
Sbjct: 2248 MATDRGSPALVGSATLTVMVIDTNDNRPT-IPQPWELRVSEDALLGSEIAQVTGNDVDSG 2306
Query: 643 ENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVT 702
LS F + G + + D EQ Y QL A DG P +T
Sbjct: 2307 PVLWYVLSPSGPQDPFSVGRYGGRVSLTGPLDFEQCDRYQLQLLAHDG---PHEGRANLT 2363
Query: 703 INVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPY 762
+ V D NDNAP + + +L T G + V+A D DSG N + Y +A +P
Sbjct: 2364 VLVEDVNDNAPAFS--QSLYQVMLLEHTPPGSAILSVSATDRDSGANGHISYHLA--SPA 2419
Query: 763 GLFQIGSHSGAI-TLEKEIERRHHGLHR--LVVKVSDRGKPPRYGTALVHLYVNE 814
F + ++G + T+ + H G +V++ D G P R A VH+ + +
Sbjct: 2420 DGFSVDPNNGTLFTIVGTVALGHDGSGAVDVVLEARDHGAPGRAARATVHVQLQD 2474
Score = 207 bits (528), Expect = 4e-53
Identities = 161/545 (29%), Positives = 239/545 (43%), Gaps = 26/545 (4%)
Query: 284 SYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQG 343
S + ++ E P G + + A A + + Q V L +D ++G++
Sbjct: 46 SLDLQIDEEQPAGTLIGDISAGLPAGTAAPLMYFISAQEGSGVGTDLAIDEHSGVVRTAR 105
Query: 344 PVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMAN 403
+DRE RF+ + P A +V V V D+ND+AP L
Sbjct: 106 VLDREQRDRYRFTAVT------PDGATVEVTVRVADINDHAPAFPQARAAL--------Q 151
Query: 404 ISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ-LRQASETGSDSKKKYFLQTTT 462
+ E A T L D D G ++GD + R + G D L T
Sbjct: 152 VPEHTAFGTRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTG 211
Query: 463 PLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPG 522
LD E Y +++ A D G+PP + L V ++D+ND+AP F QS E+ PG
Sbjct: 212 ELDRENRSHYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFNQSRYHAVVSESLAPG 271
Query: 523 EVIAEITASDADSGSNAELVYSLEPEPA-AKGLFTISPETGEIQVKTSLDREQRESYELK 581
+ ++ ASDAD+G N + Y + + G F+I TG +Q++ LD EQR +EL
Sbjct: 272 SPVLQVFASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELV 331
Query: 582 VVAADRGSPSLQGTATVLVNVLDCNDNDPK----FMLSGYNFSVMENMPALSPVGMVTVI 637
V A D G+ G+A V V+V D NDN P F+ + + V E P V ++V
Sbjct: 332 VQARDGGAHPELGSAFVTVHVRDANDNQPSMTVIFLSADGSPQVSEAAPPGQLVARISVS 391
Query: 638 DGDKGENAQVQLSVEQDNGDFVIQNGTGTILS---SLSFDREQQSTYTFQLKAVDGGVPP 694
D D G+ A V +S+E G F + I + DRE++ Y ++ A D G PP
Sbjct: 392 DPDDGDFAHVNVSLEGGEGHFALSTQDSVIYLVCVARRLDREERDAYNLRVTATDSGSPP 451
Query: 695 RSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GETVSQVAAEDFDSGVNAELI 753
A ++V D NDNAP L P+ L G V +V A D D G N ++
Sbjct: 452 LRAEAAFVLHVTDVNDNAPAFDRQLYRPEPL--PEVALPGSFVVRVTARDPDQGTNGQVT 509
Query: 754 YSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVN 813
YS+A G F I SG IT ++ +L+V +D G PP +A V + +
Sbjct: 510 YSLAPGAHTHWFSIDPTSGIITTAASLDYELEPQPQLIVVATDGGLPPLASSATVSVALQ 569
Query: 814 ETLAN 818
+ N
Sbjct: 570 DVNDN 574
Score = 197 bits (500), Expect = 7e-50
Identities = 190/682 (27%), Positives = 288/682 (42%), Gaps = 51/682 (7%)
Query: 155 QIEVQDINDN--TPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPE 212
++ VQD+ P F SP + +P T G+ A D GP +Y L A
Sbjct: 985 RVVVQDVGTRGLAPRFNSPTYRVDLPSGTTAGTQVLQVQAQAPDGGP---ITYHL-AAEG 1040
Query: 213 AQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPP---RASSALLRVT 269
A FGL E + L V LDRE + Y L + G + +A +RV+
Sbjct: 1041 ASSPFGL------EPQSGWLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVS 1094
Query: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRL 329
+L+ N+++P+ ++EN P G SV +V A D D G N + Y+ Q E +
Sbjct: 1095 ILNQNEHSPRLSEDPTFLAVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSED-SKA 1153
Query: 330 LRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEI 389
R+ TG +T +DRE S+ + V +D G+ P+S V V V D+NDN+PT +
Sbjct: 1154 FRIHPQTGEVTTLQTLDREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTF-L 1212
Query: 390 RGIGLVTHQDGMA-NISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
+ G G+ + + V T V +Q D DEGEN + + G SE
Sbjct: 1213 QASGAAG--GGLPIQVPDRVPPGTLVTTLQAKDPDEGENGTILYTLTGP-------GSEL 1263
Query: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVV----------D 498
S L T PL + Y + + A D G+PP S++ L VQV+ D
Sbjct: 1264 FSLHPHSGELLTAAPLIRAERPHYVLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPD 1323
Query: 499 VNDNAPVFTQSVT-EVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTI 557
+ + P V V E +PG ++ + A + +G A L Y+L +G F +
Sbjct: 1324 LAERDPAAPVPVVLTVTAAEGLRPGSLLGSVAAPEP-AGVGA-LTYTLVGGADPEGTFAL 1381
Query: 558 SPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGY 617
+G + + LD E + V A+ + V V V D N++ P F
Sbjct: 1382 DAASGRLYLARPLDFEAGPPWRALTVRAEGPGGAGARLLRVQVQVQDENEHAPAFARDPL 1441
Query: 618 NFSVMENMPALSPVGMVTVIDGD-KGENAQVQ---LSVEQDNGDFVIQNGTGTILSSLSF 673
++ EN + + D D G N+ V+ L E + TG + +
Sbjct: 1442 ALALPENPEPGAALYTFRASDADGPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGL 1501
Query: 674 DREQQSTYTFQLKAVD---GGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQT 730
DRE ++A D R+A V + V DENDNAP +PS L
Sbjct: 1502 DRETTPALLLLVEATDRPANASRRRAARVSARVFVTDENDNAPVFASPSRVR---LPEDQ 1558
Query: 731 RLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRL 790
G V A D D G A + Y +A G G F++ S +GA+++ + ++R H L
Sbjct: 1559 PPGPAALHVVARDPDLGEAARVSYRLASGGD-GHFRLHSSTGALSVVRPLDREQRAEHVL 1617
Query: 791 VVKVSDRGKPPRYGTALVHLYV 812
V SD G PPR T ++ + V
Sbjct: 1618 TVVASDHGSPPRSATQVLTVSV 1639
Score = 189 bits (479), Expect = 2e-47
Identities = 199/774 (25%), Positives = 334/774 (43%), Gaps = 88/774 (11%)
Query: 61 VYKVPEEQPPNTLIGSLAADYGFPDVGHL-YKLEVGAP--YLRVDGKTGDIFTTETSIDR 117
V+ VPE+ P T +G + A + + L G P +D +G + T +DR
Sbjct: 796 VFSVPEDVAPGTSVGIVQAHNPPGRLAPVTLSLSGGDPRGLFSLDAVSG-LLQTLRPLDR 854
Query: 118 EGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEV--QDINDNTPNFASPVITL 175
E L +LE EV V P ++ V D+NDN+P F +P T+
Sbjct: 855 ELLGP----------VLELEVRAGSGVP---PAFAVARVRVLLDDVNDNSPAFPAPEDTV 901
Query: 176 AIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVM 235
+P NT G+ A D D+G N ++ L AG A + + +M
Sbjct: 902 LLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGG--------AFTVDPTTGHVRLM 953
Query: 236 GNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLD--TNDNAPKFERPSYEAELSENS 293
L +++L ++ +DGGSPPR S LRV V D T AP+F P+Y +L +
Sbjct: 954 RPLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRVDLPSGT 1013
Query: 294 PIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDRE--DLS 351
G V+QV+A D G T+H A E L+ +G + V+ +DRE +L
Sbjct: 1014 TAGTQVLQVQAQAPDGG-----PITYHLAAEGASSPFGLEPQSGWLWVRAALDREAQELY 1068
Query: 352 TLRFSVLAKDRG-TNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAE 410
L+ ++ + ++ A V V++ + N+++P + + ++E+
Sbjct: 1069 ILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRL--------SEDPTFLAVAENQPP 1120
Query: 411 ETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSK------KKYFLQTTTPL 464
T+V V +DRD G N +T + L+Q SE DSK + + T L
Sbjct: 1121 GTSVGRVFATDRDSGPNGRLT--------YSLQQLSE---DSKAFRIHPQTGEVTTLQTL 1169
Query: 465 DYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSV------TEVAFPEN 518
D E+ Y + + D G+PP S+T ++ V V+D+NDN+P F Q+ + P+
Sbjct: 1170 DREQQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDR 1229
Query: 519 NKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESY 578
PG ++ + A D D G N ++Y+L P ++ LF++ P +GE+ L R +R Y
Sbjct: 1230 VPPGTLVTTLQAKDPDEGENGTILYTL-TGPGSE-LFSLHPHSGELLTAAPLIRAERPHY 1287
Query: 579 ELKVVAADRGSPSLQGTATVLVNVL----------DCNDNDPKFMLS-GYNFSVMENMPA 627
L + A D+GSP + +LV VL D + DP + + E +
Sbjct: 1288 VLTLSAHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRP 1347
Query: 628 LSPVGMVTVID-GDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLK 686
S +G V + G + G F + +G + + D E +
Sbjct: 1348 GSLLGSVAAPEPAGVGALTYTLVGGADPEGTFALDAASGRLYLARPLDFEAGPPWRALTV 1407
Query: 687 AVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQT-RLGETVSQVAAEDFD 745
+G + + V + V DEN++AP A + L P+ G + A D D
Sbjct: 1408 RAEGPGGAGARLLRVQVQVQDENEHAP---AFARDPLALALPENPEPGAALYTFRASDAD 1464
Query: 746 S-GVNAELIYSIAGGN-PYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDR 797
G N+++ Y + P ++ + +GA++ + ++R L+V+ +DR
Sbjct: 1465 GPGPNSDVRYRLLRQEPPVPALRLDARTGALSAPRGLDRETTPALLLLVEATDR 1518
Score = 187 bits (476), Expect = 4e-47
Identities = 175/649 (26%), Positives = 283/649 (43%), Gaps = 74/649 (11%)
Query: 166 PNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQ-AGPEAQELFGLQVAED 224
P F ++PE+ G+ I A + P +A L +G + + LF L
Sbjct: 788 PIFEQLQYVFSVPEDVAPGTSVGIVQAHNP---PGRLAPVTLSLSGGDPRGLFSLDAVSG 844
Query: 225 QEEKQPQLIVMGNLDRERWDSYDLTIKVQDG-GSPPRASSALLRVTVLDTNDNAPKFERP 283
L + LDRE L ++V+ G G PP + A +RV + D NDN+P F P
Sbjct: 845 L------LQTLRPLDRELLGPV-LELEVRAGSGVPPAFAVARVRVLLDDVNDNSPAFPAP 897
Query: 284 SYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQG 343
L N+ G + ++A D D G N+ + +T +D TG + +
Sbjct: 898 EDTVLLPPNTAPGTPIYTLRALDPDSGVNSRVTFTLLAGGGGA---FTVDPTTGHVRLMR 954
Query: 344 PVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMND-------NAPTIEIRGIGLVT 396
P+ + A+D G+ P+++ ++ V V+D+ N+PT +
Sbjct: 955 PLGPSGGPAHELELEARDGGSPPRTSHFRLRVVVQDVGTRGLAPRFNSPTYRV------- 1007
Query: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
++ T V VQ D G PF L S
Sbjct: 1008 ------DLPSGTTAGTQVLQVQAQAPDGGPITYHLAAEGASSPFGLEPQSG--------- 1052
Query: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPL---SSTNSLKVQVVDVNDNAPVFTQSVTEV 513
+L LD E + Y ++++AV L + T +++V +++ N+++P ++ T +
Sbjct: 1053 WLWVRAALDREAQELYILKVMAVSGSKAELGQQTGTATVRVSILNQNEHSPRLSEDPTFL 1112
Query: 514 AFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDRE 573
A EN PG + + A+D DSG N L YSL+ F I P+TGE+ +LDRE
Sbjct: 1113 AVAENQPPGTSVGRVFATDRDSGPNGRLTYSLQQLSEDSKAFRIHPQTGEVTTLQTLDRE 1172
Query: 574 QRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLS------GYNFSVMENMPA 627
Q+ SY+L V D GSP T TV V VLD NDN P F+ + G V + +P
Sbjct: 1173 QQSSYQLLVQVQDGGSPPRSTTGTVHVAVLDLNDNSPTFLQASGAAGGGLPIQVPDRVPP 1232
Query: 628 LSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTYTFQLK 686
+ V + D D+GEN + ++ + F + +G +L++ R ++ Y L
Sbjct: 1233 GTLVTTLQAKDPDEGENGTILYTLTGPGSELFSLHPHSGELLTAAPLIRAERPHYVLTLS 1292
Query: 687 AVDGGVPPRSAYVGVTINVL-------------DENDNAPYITAPSNTSHKLLTPQTRLG 733
A D G PPRSA + + + VL + + AP + T+ + L P + LG
Sbjct: 1293 AHDQGSPPRSASLQLLVQVLPSARLAEPPPDLAERDPAAPVPVVLTVTAAEGLRPGSLLG 1352
Query: 734 ETVSQVAAEDFDSGVNAELIYSIAGG-NPYGLFQIGSHSGAITLEKEIE 781
VAA + +GV A L Y++ GG +P G F + + SG + L + ++
Sbjct: 1353 ----SVAAPE-PAGVGA-LTYTLVGGADPEGTFALDAASGRLYLARPLD 1395
Score = 144 bits (364), Expect = 4e-34
Identities = 147/573 (25%), Positives = 249/573 (43%), Gaps = 75/573 (13%)
Query: 66 EEQPPNTLIGSLAA-DYGFPDVGHL-YKLEVGAPYLRVDGKTGDIFTTETSI----DREG 119
E PP + I S++A D GH+ Y L A VD G +FT ++ D G
Sbjct: 2387 EHTPPGSAILSVSATDRDSGANGHISYHLASPADGFSVDPNNGTLFTIVGTVALGHDGSG 2446
Query: 120 LRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPE 179
++ + D G +++QD ND+ P+F +A+ E
Sbjct: 2447 A-------------VDVVLEARDHGAPGRAARATVHVQLQDQNDHAPSFTLSHYRVAVTE 2493
Query: 180 NTNIGSLFPIPLASDRDAGPNGVA-SYELQAGPEAQELFGLQ--VAEDQEEKQPQ----- 231
+ GS A+D D + A Y + +G + +F L+ +AE E P
Sbjct: 2494 DLPPGSTLLTLEATDADGSRSHAAVDYSIISGNWGR-VFQLEPRLAEAGESAGPGPRALG 2552
Query: 232 -LIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELS 290
L+++ LD E Y+LT+ D G PP++S + VTVLD NDN P F R SY +
Sbjct: 2553 CLVLLEPLDFESLTQYNLTVAAADRGQPPQSSVVPVTVTVLDVNDNPPVFTRASYRVTVP 2612
Query: 291 ENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDL 350
E++P+G ++ V+A+D+D G + + +T L LD ++G + + +D E
Sbjct: 2613 EDTPVGAELLHVEASDADPGPHGLVRFTVSSGDP--SGLFELDESSGTLRLAHALDCETQ 2670
Query: 351 STLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAE 410
+ + V A D A A V + V+D+ND+ P + + +++E+
Sbjct: 2671 ARHQLVVQAAD-PAGAHFALAPVTIEVQDVNDHGPAFPLNLLS--------TSVAENQPP 2721
Query: 411 ETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTT-------P 463
T V + D D G G + + L +A G + ++ + L ++T P
Sbjct: 2722 GTLVTTLHAIDGDAG--------AFGRLRYSLLEAG-PGPEGREAFALNSSTGELRARVP 2772
Query: 464 LDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGE 523
DYE + + + + A D+GN LS++ ++ V V ++ PVF PE + G
Sbjct: 2773 FDYEHTESFRLLVGAADAGN--LSASVTVSVLVTGEDEYDPVFLAPAFHFQVPEGARRGH 2830
Query: 524 VIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL------------- 570
+ + A+D D G++ ++YSL + F I+ TG + ++
Sbjct: 2831 SLGHVQATDEDGGADGLVLYSL---ATSSPYFGINQTTGALYLRVDSRAPGSGTATSGGG 2887
Query: 571 DREQRES-YELKVVAADRGSPSLQGTATVLVNV 602
R +RE+ EL++ RG +ATV V V
Sbjct: 2888 GRTRREAPRELRLEVIARGPLPGSRSATVPVTV 2920
Score = 117 bits (292), Expect = 9e-26
Identities = 99/345 (28%), Positives = 153/345 (44%), Gaps = 25/345 (7%)
Query: 512 EVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFT---ISPETGEIQVKT 568
++ E G +I +I+A +G+ A L+Y + + + G+ T I +G ++
Sbjct: 48 DLQIDEEQPAGTLIGDISAG-LPAGTAAPLMYFISAQEGS-GVGTDLAIDEHSGVVRTAR 105
Query: 569 SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL 628
LDREQR+ Y V D T V V V D ND+ P F + V E+
Sbjct: 106 VLDREQRDRYRFTAVTPDGA------TVEVTVRVADINDHAPAFPQARAALQVPEHTAFG 159
Query: 629 SPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGT-----GTILSSL----SFDREQQS 679
+ + D D G ++ D + T GT + L DRE +S
Sbjct: 160 TRYPLEPARDADAGRLGTQGYALSGDGAGETFRLETRPGPDGTPVPELVVTGELDRENRS 219
Query: 680 TYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQV 739
Y QL+A DGG PPR A + + +LD ND+AP + H +++ G V QV
Sbjct: 220 HYMLQLEAYDGGSPPRRAQALLDVTLLDINDHAPAFN--QSRYHAVVSESLAPGSPVLQV 277
Query: 740 AAEDFDSGVNAELIYSI--AGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDR 797
A D D+GVN + Y I G F I +H+G + LE+ ++ +H LVV+ D
Sbjct: 278 FASDADAGVNGAVTYEINRRQSEGDGPFSIDAHTGLLQLERPLDFEQRRVHELVVQARDG 337
Query: 798 GKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDP 842
G P G+A V ++V + N+ + T++ S D + A P
Sbjct: 338 GAHPELGSAFVTVHVRDANDNQPSM-TVIFLSADGSPQVSEAAPP 381
Score = 33.1 bits (74), Expect = 1.7
Identities = 52/216 (24%), Positives = 78/216 (36%), Gaps = 19/216 (8%)
Query: 64 VPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLREC 123
V E QPP TL+ +L A G D G +L + + F +S E
Sbjct: 2715 VAENQPPGTLVTTLHAIDG--DAGAFGRLRYSLLEAGPGPEGREAFALNSSTG-----EL 2767
Query: 124 QNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDI----NDNTPNFASPVITLAIPE 179
+ ++P D E S LV L + V + ++ P F +P +PE
Sbjct: 2768 RARVPFD---YEHTESFRLLVGAADAGNLSASVTVSVLVTGEDEYDPVFLAPAFHFQVPE 2824
Query: 180 NTNIGSLFPIPLASDRDAGPNGVASYELQAGPE----AQELFGLQVAEDQEEKQPQLIVM 235
G A+D D G +G+ Y L Q L + D
Sbjct: 2825 GARRGHSLGHVQATDEDGGADGLVLYSLATSSPYFGINQTTGALYLRVDSRAPGSGTATS 2884
Query: 236 GNLDRERWDS-YDLTIKVQDGGSPPRASSALLRVTV 270
G R R ++ +L ++V G P + SA + VTV
Sbjct: 2885 GGGGRTRREAPRELRLEVIARGPLPGSRSATVPVTV 2920
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 343 bits (881), Expect = 4e-94
Identities = 258/802 (32%), Positives = 391/802 (48%), Gaps = 58/802 (7%)
Query: 41 SMLLALLLLLAPSPGHA------TRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEV 94
S LL + LL+ PG A R V++V EEQPP TL+G++ GF Y+L
Sbjct: 22 SQLLRVFWLLSLLPGQAWVHGAEPRQVFQVLEEQPPGTLVGTIQTRPGFT-----YRLSE 76
Query: 95 GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRL-LE 153
++ TG ++TT T IDRE L P D L +V + +P E
Sbjct: 77 SHALFAINSSTGALYTTST-IDRESL-------PSDVINL--------VVLSSAPTYPTE 120
Query: 154 GQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGV--ASYELQAGP 211
++ V+D+NDN P F P I + E+++ G + A+D D G NGV SY + G
Sbjct: 121 VRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYRIIRGN 180
Query: 212 EAQEL-FGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTV 270
EA + + E L+ G LDRE Y L ++V+D G P R + VTV
Sbjct: 181 EAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQVNVTV 240
Query: 271 LDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLL 330
D NDN P F Y+A + E++ +G SV+QV A D+D+G NA+I Y
Sbjct: 241 QDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP----F 296
Query: 331 RLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIR 390
++D TGLITV+ P+D E +V A DRG + RA+ ++ + D+NDN P ++ R
Sbjct: 297 QMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDNDPVVKFR 356
Query: 391 GIGLVTHQDGMANISEDVAEETAVALVQVSDRDE-GENAAVTCVVAGDVPFQLRQASETG 449
+ A++ E+ T VAL+ V+D D N ++ + G + R
Sbjct: 357 YFPATSR---YASVDENAQVGTVVALLTVTDADSPAANGNISVQILGG--NEQRHFEVQS 411
Query: 450 SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDS-GNPP------LSSTNSLKVQVVDVNDN 502
S ++ + LD E++ Y + + D+ G PP SS SL + V D+ND+
Sbjct: 412 SKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDH 471
Query: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
PVF+Q V V E PG ++ I+A+D DSG NA L YS+ G F IS +G
Sbjct: 472 PPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI-VSGNGLGWFHISEHSG 530
Query: 563 EIQVKTS--LDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKF-MLSGYNF 619
+ +S LDRE L + A D+G A ++V +LD ND P F GY+
Sbjct: 531 LVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDV 590
Query: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSV---EQDNGDFVIQNGTGTILSSLSFDRE 676
SV+EN P + + M+ DGD G+N V+ S+ E D F + +G + + S DRE
Sbjct: 591 SVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDRE 650
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETV 736
+Q+ Y+ + A D G PP+S+ + +++LD NDN+P +H + G +
Sbjct: 651 EQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAH--IKENEPGGSYI 708
Query: 737 SQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSD 796
+ V+A D D G N + YSI+ G+ FQ+ + SG I+ ++R ++L + +D
Sbjct: 709 TTVSATDPDLGTNGTVKYSISAGD-RSRFQVNAQSGVISTRMALDREEKTAYQLQIVATD 767
Query: 797 RGKPPRYGTALVHLYVNETLAN 818
G A+V + V +T N
Sbjct: 768 GGNLQSPNQAIVTITVLDTQDN 789
Score = 290 bits (743), Expect = 4e-78
Identities = 229/764 (29%), Positives = 367/764 (48%), Gaps = 79/764 (10%)
Query: 90 YKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSIT-DLVQNGS 148
Y+L+ ++D +TG + T +D E R+ S+T + G
Sbjct: 287 YRLQDEGTPFQMDPETG-LITVREPLDFEARRQ---------------YSLTVQAMDRGV 330
Query: 149 PRLL---EGQIEVQDINDNTP-----NFASPVITLAIPENTNIGSLFPIPLASDRDA-GP 199
P L E I++ D+NDN P F + ++ EN +G++ + +D D+
Sbjct: 331 PSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPAA 390
Query: 200 NGVASYELQAGPEAQELFGLQVAEDQEEKQPQLI---VMGNLDRERWDSYDLTIKVQDG- 255
NG S ++ G E + E Q K P L V LDRER SY+LT+ V D
Sbjct: 391 NGNISVQILGGNEQRHF------EVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNY 444
Query: 256 GSPP------RASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQ 309
G+PP R+S A L + V D ND+ P F + Y LSE +P G V + A D D
Sbjct: 445 GAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDS 504
Query: 310 GANAEIEYTFHQAPEVVRRLLRLDRNTGLITV--QGPVDREDLSTLRFSVLAKDRGTNPK 367
G NA + Y+ + + ++GL+T G +DRE S + ++ A+D+G +PK
Sbjct: 505 GLNANLRYSIVSGNGL--GWFHISEHSGLVTTGSSGGLDRELASQIVLNISARDQGVHPK 562
Query: 368 SARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGM-ANISEDVAEETAVALVQVSDRDEGE 426
+ AQ+VVT+ D+ND P + +G ++ E+ T + +++ +D D G+
Sbjct: 563 VSYAQLVVTLLDVNDEKPVF--------SQPEGYDVSVVENAPTGTELLMLRATDGDLGD 614
Query: 427 NAAVTCVVAGDVPFQLRQASETGSDSKK----KYFLQTTTPLDYEKVKDYTIEIVAVDSG 482
N G V F L++A ET S + L T + LD E+ Y++ ++A D G
Sbjct: 615 N--------GTVRFSLQEA-ETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLG 665
Query: 483 NPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELV 542
+PP SS + V ++D+NDN+PVF EN G I ++A+D D G+N +
Sbjct: 666 SPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVK 725
Query: 543 YSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNV 602
YS+ ++ F ++ ++G I + +LDRE++ +Y+L++VA D G+ A V + V
Sbjct: 726 YSISAGDRSR--FQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITV 783
Query: 603 LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQN 662
LD DN P F Y+F V EN+ VG V+ D N ++ G F I
Sbjct: 784 LDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYLITTGDQKGMFAINQ 843
Query: 663 GTGTILSSLSFDREQQSTYTFQLKAV-DGGVPPRSAYVGVTINVLDENDNAPYITAPSNT 721
TG + ++ DRE+QS Y QLK V GG V +T+ D NDN+P+ +
Sbjct: 844 VTGQLTTANVIDREEQSFY--QLKVVASGGTVTGDTMVNITVK--DLNDNSPHFLQAIES 899
Query: 722 SHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIE 781
+ + + G ++ Q A D D GVN ++YS+ NP LF I +G I+L ++
Sbjct: 900 VN--VVENWQAGHSIFQAKAVDPDEGVNGMVLYSLK-QNPKNLFAINEKNGTISLLGPLD 956
Query: 782 RRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETL 825
H G +++ + SD G P + ++ +YV++ N + + L
Sbjct: 957 -VHAGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQL 999
Score = 290 bits (741), Expect = 8e-78
Identities = 224/688 (32%), Positives = 324/688 (47%), Gaps = 53/688 (7%)
Query: 135 EFEVSITDLVQNGSPRLLEGQI---EVQDINDNTPNFASPVITLAIPENTNIGSLFPIPL 191
+ E+ +D+ G P+L I V D+NDN+P F + + E+ + S F
Sbjct: 963 QIEILASDM---GVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQ 1019
Query: 192 ASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIK 251
ASD+D+G NG +Y + G + FG+ QL + LDRE D Y L +
Sbjct: 1020 ASDKDSGANGEIAYTIAEG-NTGDAFGIF-------PDGQLYIKSELDRELQDRYVLMVV 1071
Query: 252 VQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGA 311
D P +++ + V + D NDN P F +Y E G V +V A D D G
Sbjct: 1072 ASDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGP 1131
Query: 312 NAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLR------FSVLAKDRGT- 364
N E+ Y+F E+V+ L +G IT DRE L R F+V+A D+G
Sbjct: 1132 NGEVRYSF----EMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIP 1187
Query: 365 NPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDE 424
P +A V V +KD+NDNAP A ISE A T V V SD DE
Sbjct: 1188 QPLKDQATVHVYMKDINDNAPKF--------LKDFYQATISESAANLTQVLRVSASDVDE 1239
Query: 425 GENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGN 483
G N + ++ G+ Q S +G + LDYE Y++ I AVDSG
Sbjct: 1240 GNNGLIHYSIIKGNEERQFAIDSTSGQ-------VTLIGKLDYEATPAYSLVIQAVDSGT 1292
Query: 484 PPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVY 543
PL+ST +L + ++D NDN P F +S V EN + GE+++ +TA+D+DSG NA+L Y
Sbjct: 1293 IPLNSTCTLNIDILDENDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYY 1352
Query: 544 SLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVL 603
S+ G F+ISP TG I + LD E + Y+L + A D+G P T +V+++V
Sbjct: 1353 SI-TGTNNHGTFSISPNTGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVR 1411
Query: 604 DCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD---NGDFVI 660
D NDN P F S++EN+P + V VT D D N Q+ ++ Q F I
Sbjct: 1412 DFNDNPPSFPPGDIFKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTI 1471
Query: 661 QNGTGTILSSLSFDREQQSTYTFQLKAVDGGVP---PRSAYVGVTINVLDENDNAPYITA 717
GTI ++ DRE + + +KA D VP R A VTI V D NDN P +
Sbjct: 1472 DEVKGTIYTNAEIDREFANLFELTVKANDQAVPIETRRYALKNVTILVTDLNDNVPMFIS 1531
Query: 718 PSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLE 777
+ + P +G ++ + A D D G N E+ Y I G+ F + +SG + +
Sbjct: 1532 QNALA---ADPSAVIGSVLTTIMAADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVA 1587
Query: 778 KEIERRHHGLHRLVVKVSDRGKPPRYGT 805
+ ++ L+V +D G R T
Sbjct: 1588 SALVPSQL-IYNLIVSATDLGPERRKST 1614
Score = 284 bits (726), Expect = 4e-76
Identities = 222/762 (29%), Positives = 351/762 (46%), Gaps = 58/762 (7%)
Query: 64 VPEEQPPNTLIGSLAADYGFPDVGH----LYKLEVG-APYLRVDGKTGDIFTTETSIDRE 118
+ E +P + I +++A PD+G Y + G +V+ ++G + +T ++DRE
Sbjct: 698 IKENEPGGSYITTVSATD--PDLGTNGTVKYSISAGDRSRFQVNAQSG-VISTRMALDRE 754
Query: 119 GLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIP 178
+ + ++ TD SP I V D DN P F+ + +
Sbjct: 755 -----------EKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVF 803
Query: 179 ENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNL 238
EN +G AS D N SY + G + + +F + + QL +
Sbjct: 804 ENVALGYHVGSVSASTMDLNSN--ISYLITTGDQ-KGMFAIN------QVTGQLTTANVI 854
Query: 239 DRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHS 298
DRE Y L + V GG+ ++ +TV D NDN+P F + + EN GHS
Sbjct: 855 DREEQSFYQLKV-VASGGTV--TGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQAGHS 911
Query: 299 VIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVL 358
+ Q KA D D+G N + Y+ Q P + L ++ G I++ GP+D + + +L
Sbjct: 912 IFQAKAVDPDEGVNGMVLYSLKQNP---KNLFAINEKNGTISLLGPLDVH-AGSYQIEIL 967
Query: 359 AKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQ 418
A D G S+ + V V D+NDN+P + + +SE + VQ
Sbjct: 968 ASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVT--------LSESEPVNSRFFKVQ 1019
Query: 419 VSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVA 478
SD+D G N + +A G L + LD E Y + +VA
Sbjct: 1020 ASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ-------LYIKSELDRELQDRYVLMVVA 1072
Query: 479 VDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
D PLS+T ++ V + DVNDN P+F + F E + G + +++A D D G N
Sbjct: 1073 SDRAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPN 1132
Query: 539 AELVYSLEPEPAAKGLFTISPE---TGEIQVKTSLDREQRESYELKVVAADRGSPS-LQG 594
E+ YS E L IS E T + ++ + R + V+A D+G P L+
Sbjct: 1133 GEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKD 1192
Query: 595 TATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQD 654
ATV V + D NDN PKF+ Y ++ E+ L+ V V+ D D+G N + S+ +
Sbjct: 1193 QATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKG 1252
Query: 655 NGD--FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNA 712
N + F I + +G + D E Y+ ++AVD G P ++ + I++LDENDN
Sbjct: 1253 NEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNT 1312
Query: 713 PYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSG 772
P + P +T + R+GE VS V A D DSG NA+L YSI G N +G F I ++G
Sbjct: 1313 P--SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTG 1370
Query: 773 AITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNE 814
+I L K+++ L++L + D+G+PPR T V ++V +
Sbjct: 1371 SIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRD 1412
Score = 276 bits (705), Expect = 1e-73
Identities = 213/674 (31%), Positives = 322/674 (47%), Gaps = 53/674 (7%)
Query: 138 VSITDLVQNGSPRLL---EGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASD 194
V + DL Q + R + I + D+NDN P F SP +T IPENT I ++ A+D
Sbjct: 2018 VQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATD 2076
Query: 195 RDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQD 254
D+GPN Y L P + F + + + + G LDRE +Y LT+ D
Sbjct: 2077 PDSGPNSYIEYTL-LNPLGNK-FSIGTIDGEVR------LTGELDREEVSNYTLTVVATD 2128
Query: 255 GGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAE 314
G P +SS + V VLD NDN P F + Y+ E++EN+ G +IQV A D D+G N +
Sbjct: 2129 KGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQ 2188
Query: 315 IEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
+ Y + R+D TG ITV P+DRE T +V A DRG+ P++ + V
Sbjct: 2189 VRYGIVNGN--TNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVS 2246
Query: 375 VTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVS-DRDEGENAAVTCV 433
+ + D+ND P E+ + N+ E++ L V+ D D G N+ ++ V
Sbjct: 2247 IVLLDINDFVPVFELSPYSV--------NVPENLGTLPRTILQVVARDDDRGSNSKLSYV 2298
Query: 434 VAG---DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN 490
+ G D F L + E G T LD E + + + I A DSG+P L+ T
Sbjct: 2299 LFGGNEDNAFTLSASGELG----------VTQSLDRETKERFVLMITATDSGSPALTGTG 2348
Query: 491 SLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA 550
++ V V DVNDN P F PE+ G + + ASDAD+ NA +
Sbjct: 2349 TINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRII-----G 2403
Query: 551 AKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPS-LQGTATVLVNVLDCNDND 609
FTI+P TG+I LDRE +++Y L VV +D GSP L + +VLV V D NDN
Sbjct: 2404 GNSQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNP 2463
Query: 610 PKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTIL 668
P+F Y + S V VTV D D G N+++ S+ N + F I G I+
Sbjct: 2464 PRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPLRGAIM 2523
Query: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
++ + + T++ +K DGG P++ VT+ +++ D P + A T + P
Sbjct: 2524 AAGPLNGASEVTFSVHVK--DGGSFPKTDSTTVTVRFVNKAD-FPKVRAKEQT---FMFP 2577
Query: 729 QTRLGETVSQVAAEDFDSGVNAE-LIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
+ + VS + S + E + Y IA GN FQI +G +++ + ++
Sbjct: 2578 EN---QPVSSLVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQK 2634
Query: 788 HRLVVKVSDRGKPP 801
+ + ++ D G PP
Sbjct: 2635 YVVWIEARDGGFPP 2648
Score = 274 bits (701), Expect = 3e-73
Identities = 216/706 (30%), Positives = 326/706 (46%), Gaps = 55/706 (7%)
Query: 100 RVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQ 159
R+D ++GD+ T +DRE + + D D +Q+ R+ I V
Sbjct: 1788 RIDPESGDLIATRR-LDRERRSKYSLLVRAD-----------DGLQSSDMRI---NITVS 1832
Query: 160 DINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGL 219
D+ND+TP F+ PV + IPE+T GSL LA+D D+G NG +Y + E F
Sbjct: 1833 DVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDGIFFLN 1892
Query: 220 QVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPK 279
+ + LD E Y LT++ +DGG + ++ + +LD NDN P
Sbjct: 1893 PITG-------VFNLTRLLDYEVQQYYILTVRAEDGGG--QFTTIRVYFNILDVNDNPPI 1943
Query: 280 FERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLI 339
F SY L EN P+G +V+ D+D G N+++ Y+ + + +D+N G++
Sbjct: 1944 FSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQ--FTVDKN-GVL 2000
Query: 340 TVQGPVDREDLSTLRFSVLAKDRGTNPKS---ARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
V +DRE S V D P S + AQV + + D+NDN PT
Sbjct: 2001 KVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFL-------- 2052
Query: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
+ I E+ +T V Q +D D G N+ + + + + + G
Sbjct: 2053 -SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFSIGTIDGE------ 2105
Query: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
++ T LD E+V +YT+ +VA D G P LSS+ + V V+D+NDN P+F Q++ +V
Sbjct: 2106 -VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEIN 2164
Query: 517 ENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRE 576
EN G I ++ A+D D G+N ++ Y + F I TG I V LDRE+
Sbjct: 2165 ENTLTGTDIIQVFAADGDEGTNGQVRYGI-VNGNTNQEFRIDSVTGAITVAKPLDREKTP 2223
Query: 577 SYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL-SPVGMVT 635
+Y L V A DRGS T+TV + +LD ND P F LS Y+ +V EN+ L + V
Sbjct: 2224 TYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV 2283
Query: 636 VIDGDKGENAQVQLSVEQDNGDFVIQ-NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPP 694
D D+G N+++ + N D + +G + + S DRE + + + A D G P
Sbjct: 2284 ARDDDRGSNSKLSYVLFGGNEDNAFTLSASGELGVTQSLDRETKERFVLMITATDSGSPA 2343
Query: 695 RSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIY 754
+ + + V D NDN P T S + G V V A D D+ NA +
Sbjct: 2344 LTGTGTINVIVDDVNDNVP--TFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA--VI 2399
Query: 755 SIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
I GGN F I +G I ++R + LVV SD G P
Sbjct: 2400 RIIGGN--SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSP 2443
Score = 273 bits (698), Expect = 7e-73
Identities = 215/727 (29%), Positives = 338/727 (46%), Gaps = 56/727 (7%)
Query: 149 PRLLEGQIEV--QDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
PR ++E+ QDINDN P F + ++ L + EN GS A D D G N + +Y
Sbjct: 1719 PRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYT 1778
Query: 207 LQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALL 266
+ +G A + F + + + LI LDRER Y L ++ DG ++S +
Sbjct: 1779 IISG--ADDSFRI------DPESGDLIATRRLDRERRSKYSLLVRADDG---LQSSDMRI 1827
Query: 267 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVV 326
+TV D ND+ PKF RP Y ++ E++ G V + A D D G N EI Y ++ E
Sbjct: 1828 NITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNGEITYIVNEDDE-- 1885
Query: 327 RRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPT 386
+ L+ TG+ + +D E +V A+D G + R V + D+NDN P
Sbjct: 1886 DGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQFTTIR--VYFNILDVNDNPPI 1943
Query: 387 IEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS 446
+ ++ E++ + V + V+D D+G N+ +T +A
Sbjct: 1944 FSLNSYS--------TSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQFTVD 1995
Query: 447 ETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLS---STNSLKVQVVDVNDNA 503
+ G L+ LD E Y + + D P S ST + + ++DVNDN
Sbjct: 1996 KNG-------VLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNP 2048
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
P F S PEN V+ + A+D DSG N+ + Y+L K F+I GE
Sbjct: 2049 PTFL-SPKLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK--FSIGTIDGE 2105
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+++ LDRE+ +Y L VVA D+G PSL + V+V VLD NDN+P F + Y + E
Sbjct: 2106 VRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINE 2165
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG--DFVIQNGTGTILSSLSFDREQQSTY 681
N + + V DGD+G N QV+ + N +F I + TG I + DRE+ TY
Sbjct: 2166 NTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTY 2225
Query: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQT--RLGETVSQV 739
++A D G PR+ V+I +LD ND P + + + P+ L T+ QV
Sbjct: 2226 HLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL---SPYSVNVPENLGTLPRTILQV 2282
Query: 740 AAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGK 799
A D D G N++L Y + GGN F + S SG + + + ++R L++ +D G
Sbjct: 2283 VARDDDRGSNSKLSYVLFGGNEDNAFTL-SASGELGVTQSLDRETKERFVLMITATDSGS 2341
Query: 800 PPRYGTALVHLYVNE------TLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNI 853
P GT +++ V++ T A++ T + T D+ + + + SK N
Sbjct: 2342 PALTGTGTINVIVDDVNDNVPTFASKAYF-TTIPEDAPTGTDVLLVNASDADASK---NA 2397
Query: 854 LFGVVAG 860
+ ++ G
Sbjct: 2398 VIRIIGG 2404
Score = 260 bits (665), Expect = 5e-69
Identities = 197/663 (29%), Positives = 309/663 (46%), Gaps = 31/663 (4%)
Query: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
I V D+NDN P F I EN + + + A D+D+GPNG YE+ G +
Sbjct: 2657 ITVLDVNDNAPIFKEDPFISEILENLSPRKILTVS-AMDKDSGPNGQLDYEIVNG-NMEN 2714
Query: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
F + A + + LDRE+ Y LTIK D GSP +++S + + +LD ND
Sbjct: 2715 SFSINHATGEIRS------VRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDEND 2768
Query: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
NAP+F + + A + ENSP+G++V +V +D D G NA Y+ A ++ +
Sbjct: 2769 NAPRFSQ-IFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDA----SLPFTINPS 2823
Query: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
TG I + P++RED R V A D G + V + V D+NDNAP L
Sbjct: 2824 TGDIVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDINDNAPRFSRTSYYL- 2879
Query: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKK 455
+ E + V V +D DEG N V + + A+ +K+
Sbjct: 2880 -------DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQI 2932
Query: 456 YFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAF 515
Q T + ++ + + D G P L S ++ + +VD NDNAP F +S
Sbjct: 2933 LKYQNVTGFSNVNINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPV 2992
Query: 516 PENNKPGEVIAEITA-SDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQ 574
+N K G + +TA D D G N+E+ Y + + G F + +TG I V +SL +
Sbjct: 2993 TKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHL-GKFKLDNDTGWISVASSLISDL 3051
Query: 575 RESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMV 634
+++ + V A D+G+P L ATV + V + N + P+F S + ++ E+ S V V
Sbjct: 3052 NQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTV 3111
Query: 635 TVIDGDKGENAQVQLSVEQDN--GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGV 692
+ D D N ++ S+ N G F I + TG + + + D E + + A+DGG
Sbjct: 3112 SARDRDAAMNGLIKYSISSGNEEGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGW 3171
Query: 693 PPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAEL 752
R+ Y VT+NV+D NDN+P S+ + G TV + A D DSG NA +
Sbjct: 3172 VARTGYCSVTVNVIDVNDNSPVFL--SDDYFPTVLENAPSGTTVIHLNATDADSGTNAVI 3229
Query: 753 IYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
Y++ + LF I ++G IT + ++ + L VK + R A V++ +
Sbjct: 3230 AYTVQSSDS-DLFVIDPNTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQL 3288
Query: 813 NET 815
T
Sbjct: 3289 KGT 3291
Score = 260 bits (664), Expect = 6e-69
Identities = 212/669 (31%), Positives = 298/669 (44%), Gaps = 47/669 (7%)
Query: 138 VSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDA 197
V TD Q E + V DINDN P FA + + I ENT G+ A+D D
Sbjct: 2124 VVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDE 2183
Query: 198 GPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGS 257
G NG Y + G QE + + V LDRE+ +Y LT++ D GS
Sbjct: 2184 GTNGQVRYGIVNGNTNQEF-------RIDSVTGAITVAKPLDREKTPTYHLTVQATDRGS 2236
Query: 258 PPRASSALLRVTVLDTNDNAPKFERPSYEAELSEN-SPIGHSVIQVKANDSDQGANAEIE 316
PR ++ + + +LD ND P FE Y + EN + +++QV A D D+G+N+++
Sbjct: 2237 TPRTDTSTVSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLS 2296
Query: 317 YTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVT 376
Y E L +G + V +DRE + A D G+ + + V
Sbjct: 2297 YVLFGGNEDNAFTLSA---SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVI 2353
Query: 377 VKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG 436
V D+NDN PT + I ED T V LV SD D +NA + ++ G
Sbjct: 2354 VDDVNDNVPTFASKAY--------FTTIPEDAPTGTDVLLVNASDADASKNAVIR-IIGG 2404
Query: 437 DVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNP-PLSSTNSLKVQ 495
+ F + + TG + T+ LD E +YT+ +V D+G+P PLSS+ S+ V
Sbjct: 2405 NSQFTINPS--TGQ-------IITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
Query: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
V DVNDN P F P PG + +T +DAD G N+EL YSL + K F
Sbjct: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEK--F 2513
Query: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLS 615
I P G I L+ ++ + V D GS + TV V ++ D PK
Sbjct: 2514 HIDPLRGAIMAAGPLNGASEVTFSVHV--KDGGSFPKTDSTTVTVRFVNKAD-FPKVRAK 2570
Query: 616 GYNFSVMENMPALSPVGMVTVIDGD--KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSF 673
F EN P S +VT I G +GE ++ F I TG + S
Sbjct: 2571 EQTFMFPENQPVSS---LVTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQPL 2627
Query: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL--LTPQTR 731
D E+ Y ++A DGG PP S+Y + I VLD NDNAP S L L+P+
Sbjct: 2628 DFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPR-- 2685
Query: 732 LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
+ V+A D DSG N +L Y I GN F I +G I + ++R + L
Sbjct: 2686 ---KILTVSAMDKDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLT 2742
Query: 792 VKVSDRGKP 800
+K SD+G P
Sbjct: 2743 IKSSDKGSP 2751
Score = 259 bits (662), Expect = 1e-68
Identities = 237/745 (31%), Positives = 342/745 (45%), Gaps = 73/745 (9%)
Query: 70 PNTLIGSLAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPG 129
P T++ +A D D G KL Y+ G + FT S + G+ + ++
Sbjct: 2276 PRTILQVVARD---DDRGSNSKLS----YVLFGGNEDNAFTLSASGEL-GVTQSLDRETK 2327
Query: 130 DPCILEFEVSITDLVQNGSPRLL-EGQIEV--QDINDNTPNFASPVITLAIPENTNIGSL 186
+ +L ++ TD +GSP L G I V D+NDN P FAS IPE+ G+
Sbjct: 2328 ERFVLM--ITATD---SGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTD 2382
Query: 187 FPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSY 246
+ ASD DA N V + G Q+I LDRE D+Y
Sbjct: 2383 VLLVNASDADASKNAVI-----------RIIGGNSQFTINPSTGQIITSALLDRETKDNY 2431
Query: 247 DLTIKVQDGGSP-PRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKAN 305
L + D GSP P +SS + VTV D NDN P+F+ Y + + G V V
Sbjct: 2432 TLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVT 2491
Query: 306 DSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTN 365
D+D G N+E+ Y+ +D G I GP++ S + FSV KD G+
Sbjct: 2492 DADIGPNSELHYSLSGRNS---EKFHIDPLRGAIMAAGPLN--GASEVTFSVHVKDGGSF 2546
Query: 366 PKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEG 425
PK+ V V + D P + + Q M ++ V+ + S R E
Sbjct: 2547 PKTDSTTVTVRFVNKAD-FPKVRAK------EQTFMFPENQPVSS-LVTTITGSSLRGEP 2598
Query: 426 ENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPP 485
+ + G+ FQ+ Q + S S+ PLD+EK++ Y + I A D G PP
Sbjct: 2599 MSYYIASGNLGNT-FQIDQLTGQVSISQ---------PLDFEKIQKYVVWIEARDGGFPP 2648
Query: 486 LSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL 545
SS L + V+DVNDNAP+F + EN P +++ ++A D DSG N +L Y +
Sbjct: 2649 FSSYEKLDITVLDVNDNAPIFKEDPFISEILENLSPRKILT-VSAMDKDSGPNGQLDYEI 2707
Query: 546 EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDC 605
+ F+I+ TGEI+ LDRE+ Y L + ++D+GSPS + V++N+LD
Sbjct: 2708 -VNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQSTSVKVMINILDE 2766
Query: 606 NDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTG 665
NDN P+F ++ V EN P V VT D D G NA + S+ + F I TG
Sbjct: 2767 NDNAPRFS-QIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIMDASLPFTINPSTG 2825
Query: 666 TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKL 725
I+ S +RE Y ++ A D G + VTI V D NDNAP S TS+ L
Sbjct: 2826 DIVISRPLNREDTDRYRIRVSAHDSG---WTVSTDVTIFVTDINDNAPRF---SRTSYYL 2879
Query: 726 LTPQ-TRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRH 784
P+ T +G V+QV A D D G N ++ Y I + Y F+I + +G I K+I +
Sbjct: 2880 DCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEY--FRINATTGEI-FNKQILKYQ 2936
Query: 785 H---------GLHRLVVKVSDRGKP 800
+ H +V SDRGKP
Sbjct: 2937 NVTGFSNVNINRHSFIVTSSDRGKP 2961
Score = 238 bits (607), Expect = 3e-62
Identities = 198/680 (29%), Positives = 301/680 (44%), Gaps = 53/680 (7%)
Query: 140 ITDLVQNGSPR---LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRD 196
+ ++ G P+ L+ + VQDINDN P F S +PE+ +GS A+D D
Sbjct: 219 LVEVEDKGEPKRRGYLQVNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADAD 278
Query: 197 AGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGG 256
G N Y LQ ++ + + + V LD E Y LT++ D G
Sbjct: 279 EGTNADIRYRLQDEGTPFQM---------DPETGLITVREPLDFEARRQYSLTVQAMDRG 329
Query: 257 SPPRASSALLRVTVLDTNDNAPK-----FERPSYEAELSENSPIGHSVIQVKANDSDQ-G 310
P A + +LD NDN P F S A + EN+ +G V + D+D
Sbjct: 330 VPSLTGRAEALIQLLDVNDNDPVVKFRYFPATSRYASVDENAQVGTVVALLTVTDADSPA 389
Query: 311 ANAEIEYTFHQAPEVVRRLLRLDR--NTGLITVQGPVDREDLSTLRFSVLAKDRGTNP-- 366
AN I E ++ + N LI V +DRE + + +V D P
Sbjct: 390 ANGNISVQILGGNEQRHFEVQSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPG 449
Query: 367 -----KSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSD 421
+S+ A +V+ V D+ND+ P + Q N+SE+ + V+ + +D
Sbjct: 450 AAVQARSSVASLVIFVNDINDHPPVF--------SQQVYRVNLSEEAPPGSYVSGISATD 501
Query: 422 RDEGENAAVT-CVVAGDVPFQLRQASETGSDSKKKYFLQTTTP---LDYEKVKDYTIEIV 477
D G NA + +V+G+ + +G L TT LD E + I
Sbjct: 502 GDSGLNANLRYSIVSGNGLGWFHISEHSG--------LVTTGSSGGLDRELASQIVLNIS 553
Query: 478 AVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVT-EVAFPENNKPGEVIAEITASDADSG 536
A D G P S L V ++DVND PVF+Q +V+ EN G + + A+D D G
Sbjct: 554 ARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYDVSVVENAPTGTELLMLRATDGDLG 613
Query: 537 SNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTA 596
N + +SL+ + F + P +G + +SLDRE++ Y L V+A D GSP A
Sbjct: 614 DNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDREEQAFYSLLVLATDLGSPPQSSMA 673
Query: 597 TVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQ-DN 655
+ V++LD NDN P F Y + EN P S + V+ D D G N V+ S+ D
Sbjct: 674 RINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYITTVSATDPDLGTNGTVKYSISAGDR 733
Query: 656 GDFVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYI 715
F + +G I + ++ DRE+++ Y Q+ A DGG VTI VLD DN P
Sbjct: 734 SRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGGNLQSPNQAIVTITVLDTQDNPPVF 793
Query: 716 TAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAIT 775
+ + + ++ LG V V+A D +N+ + Y I G+ G+F I +G +T
Sbjct: 794 SQVAYSF--VVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQKGMFAINQVTGQLT 849
Query: 776 LEKEIERRHHGLHRLVVKVS 795
I+R ++L V S
Sbjct: 850 TANVIDREEQSFYQLKVVAS 869
Score = 236 bits (601), Expect = 1e-61
Identities = 201/691 (29%), Positives = 313/691 (45%), Gaps = 46/691 (6%)
Query: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPE--- 212
I V DINDN P F+ L PE T IGS A+D D G NG Y +++ E
Sbjct: 2860 IFVTDINDNAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFR 2919
Query: 213 ----AQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
E+F Q+ + Q + N++ R + + D G P S + +
Sbjct: 2920 INATTGEIFNKQILKYQN-----VTGFSNVNINR---HSFIVTSSDRGKPSLISETTVTI 2971
Query: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKA-NDSDQGANAEIEYTFHQAPEVVR 327
++D+NDNAP+F + Y +++N +G +I+V A +D D G N+E+EY + +
Sbjct: 2972 NIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGK 3031
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
+LD +TG I+V + + +V AKD+G P S++A V +TV + N + P
Sbjct: 3032 --FKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEF 3089
Query: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
+H A I E + + V V DRD N G + + + +E
Sbjct: 3090 S------QSHMS--ATIPESHSIGSIVRTVSARDRDAAMN--------GLIKYSISSGNE 3133
Query: 448 TG--SDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
G + + L LDYE + + + I A+D G + S+ V V+DVNDN+PV
Sbjct: 3134 EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV 3193
Query: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQ 565
F EN G + + A+DADSG+NA + Y+++ + LF I P TG I
Sbjct: 3194 FLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGVIT 3251
Query: 566 VKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENM 625
+ LD E ++SY L V A + ATV + + N+ P+F+ Y F + E
Sbjct: 3252 TQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAA 3311
Query: 626 PALSPVGMVTVIDGDKGENAQVQLSV--EQDNGDFVIQNGTGTILSSLSFDREQQSTYTF 683
P + VG V D D G + +V + F I TG I S DRE++ +
Sbjct: 3312 PKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSL 3371
Query: 684 QLKAVDGGVPPRSAYVGVTINV--LDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
++ A + G + VT+NV LD ND P T N ++ +G V+ V+A
Sbjct: 3372 KVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTL--NIYSVQISEGVPIGTHVTFVSA 3428
Query: 742 EDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKP 800
D DS + + Y I GN G F I +G IT+ E++R ++ L V D G P
Sbjct: 3429 FDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTP 3488
Query: 801 PRYGTALVHLYVNETLANRTLLETLLGHSLD 831
G+A + + + + N +L G ++
Sbjct: 3489 SATGSASLLVTLEDINDNGPMLTVSEGEVME 3519
Score = 233 bits (593), Expect = 1e-60
Identities = 182/675 (26%), Positives = 306/675 (45%), Gaps = 54/675 (8%)
Query: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
I + D NDN P F S + + +PEN+ +G SD D G N ++ Y + +A
Sbjct: 2761 INILDENDNAPRF-SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYSIM---DASL 2816
Query: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
F + + +++ L+RE D Y + + D G S + + V D ND
Sbjct: 2817 PFTINPSTGD------IVISRPLNREDTDRYRIRVSAHDSGW---TVSTDVTIFVTDIND 2867
Query: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVR-------- 327
NAP+F R SY + E + IG V QV A D D+G+N ++ Y E R
Sbjct: 2868 NAPRFSRTSYYLDCPELTEIGSKVTQVFATDPDEGSNGQVFYFIKSQSEYFRINATTGEI 2927
Query: 328 ---RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNA 384
++L+ TG V +++ F V + DRG + V + + D NDNA
Sbjct: 2928 FNKQILKYQNVTGFSNV-------NINRHSFIVTSSDRGKPSLISETTVTINIVDSNDNA 2980
Query: 385 PTIEIRGIGLVTHQDGMANISEDVAEETA-VALVQVSDRDEGENAAVTCVVAGDVPF-QL 442
P ++++V T + + + D+D G N+ V ++ D +
Sbjct: 2981 PQF--------LKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKF 3032
Query: 443 RQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDN 502
+ ++TG ++ + L + +++ I + A D GNPPLSS ++ + V + N +
Sbjct: 3033 KLDNDTG-------WISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYH 3085
Query: 503 APVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETG 562
P F+QS PE++ G ++ ++A D D+ N + YS+ +G+F I+ TG
Sbjct: 3086 TPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSIS-SGNEEGIFAINSSTG 3144
Query: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVM 622
+ + +LD E + +E+ + A D G + G +V VNV+D NDN P F+ Y +V+
Sbjct: 3145 ILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPTVL 3204
Query: 623 ENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTY 681
EN P+ + V + D D G NA + +V+ + D FVI TG I + D E + +Y
Sbjct: 3205 ENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSY 3264
Query: 682 TFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAA 741
+KA + R ++ V I + N+ P S + ++ G V +V A
Sbjct: 3265 HLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFV--SKLYYFEISEAAPKGTIVGEVFA 3322
Query: 742 EDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPP 801
D D G + E+ Y I G + FQI +G I + ++R R+ +KV +
Sbjct: 3323 SDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKE--ERVSLKVLAKNFGS 3380
Query: 802 RYGTALVHLYVNETL 816
G + + VN T+
Sbjct: 3381 IRGADIDEVTVNVTV 3395
Score = 224 bits (570), Expect = 5e-58
Identities = 219/771 (28%), Positives = 334/771 (43%), Gaps = 92/771 (11%)
Query: 70 PNTLIGS-----LAADYGFPDVGHLYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQ 124
P+ +IGS +AAD PD G ++E Y ++G T S D LR
Sbjct: 1539 PSAVIGSVLTTIMAAD---PDEGANGEIE----YEIINGDTDTFIVDRYSGD---LRVAS 1588
Query: 125 NQLPGDPCILEFEVSITDLVQNGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIG 184
+P I VS TDL E I +Q ++ P F P + E IG
Sbjct: 1589 ALVPSQ-LIYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
Query: 185 S-LFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGN------ 237
+ + I AS R G EA + + +E+ +L +G
Sbjct: 1646 TNVISIEAASPR--------------GSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQ 1691
Query: 238 ----LDRERWDSYDLT--IKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSE 291
LDRE+ L ++ + PR A + +T+ D NDN P F + + E
Sbjct: 1692 TAAILDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEE 1751
Query: 292 NSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLS 351
N G ++Q+ A D+D+GANA + YT + R+D +G + +DRE S
Sbjct: 1752 NIGDGSKIMQLTAMDADEGANALVTYTIISGAD---DSFRIDPESGDLIATRRLDRERRS 1808
Query: 352 TLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEE 411
V A D +S+ ++ +TV D+ND+ P +I ED
Sbjct: 1809 KYSLLVRADD---GLQSSDMRINITVSDVNDHTPKFSRPVYSF--------DIPEDTIPG 1857
Query: 412 TAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTP-------L 464
+ VA + +D D G N +T +V D D +FL T L
Sbjct: 1858 SLVAAILATDDDSGVNGEITYIVNED-------------DEDGIFFLNPITGVFNLTRLL 1904
Query: 465 DYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEV 524
DYE + Y + + A D G +T + ++DVNDN P+F+ + + EN G
Sbjct: 1905 DYEVQQYYILTVRAEDGGGQ--FTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGST 1962
Query: 525 IAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVA 584
+ +DAD G N++L YS+ + G FT+ + G ++V +LDRE + Y L V
Sbjct: 1963 VLVFNVTDADDGINSQLTYSIASGDSL-GQFTVD-KNGVLKVLKALDRESQSFYNLVVQV 2020
Query: 585 ADRGS-PSLQGTATVLVNV--LDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDK 641
D P+ + T+T V++ LD NDN P F+ + + EN P + V D D
Sbjct: 2021 HDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDS 2079
Query: 642 GENAQVQLSVEQDNGD-FVIQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVG 700
G N+ ++ ++ G+ F I G + + DRE+ S YT + A D G P S+
Sbjct: 2080 GPNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTE 2139
Query: 701 VTINVLDENDNAPYITAPSNTSHKL-LTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGG 759
V + VLD NDN P + +K+ + T G + QV A D D G N ++ Y I G
Sbjct: 2140 VVVMVLDINDNNPIF---AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNG 2196
Query: 760 NPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHL 810
N F+I S +GAIT+ K ++R + L V+ +DRG PR T+ V +
Sbjct: 2197 NTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSI 2247
Score = 213 bits (542), Expect = 9e-55
Identities = 192/745 (25%), Positives = 306/745 (41%), Gaps = 55/745 (7%)
Query: 84 PDVGH----LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVS 139
PD G Y ++ + Y R++ TG+IF + + + QN +
Sbjct: 2899 PDEGSNGQVFYFIKSQSEYFRINATTGEIFNKQ-------ILKYQNVTGFSNVNINRHSF 2951
Query: 140 ITDLVQNGSPRLLEGQ---IEVQDINDNTPNFASPVITLAIPENTNIGS-LFPIPLASDR 195
I G P L+ I + D NDN P F + +N +G+ L + D+
Sbjct: 2952 IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDK 3011
Query: 196 DAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDG 255
D G N Y + L ++ D + V +L + ++ +T+ +D
Sbjct: 3012 DFGLNSEVEYFIS---NDNHLGKFKLDNDTG----WISVASSLISDLNQNFFITVTAKDK 3064
Query: 256 GSPPRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEI 315
G+PP +S A + +TV + N + P+F + A + E+ IG V V A D D N I
Sbjct: 3065 GNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLI 3124
Query: 316 EYTFHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVV 375
+Y+ E + ++ +TG++T+ +D E ++ A D G ++ V V
Sbjct: 3125 KYSISSGNE--EGIFAINSSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTV 3182
Query: 376 TVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVA 435
V D+NDN+P D + E+ T V + +D D G NA + V
Sbjct: 3183 NVIDVNDNSPVF--------LSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQ 3234
Query: 436 GDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQ 495
TG + T LD+E + Y + + A + + S ++ +Q
Sbjct: 3235 SSDSDLFVIDPNTG-------VITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQ 3287
Query: 496 VVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLF 555
+ N+ P F + E G ++ E+ ASD D G++ E+ Y + KG F
Sbjct: 3288 LKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKG-F 3346
Query: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGT----ATVLVNVLDCNDNDPK 611
I+ +TG+I V LDRE+ E LKV+A + GS ++G TV V VLD ND P
Sbjct: 3347 QINKKTGQIYVSGILDREKEERVSLKVLAKNFGS--IRGADIDEVTVNVTVLDAND-PPI 3403
Query: 612 FMLSGYNFSVMENMPALSPVGMVTVIDGDK---GENAQVQLSVEQDNGDFVIQNGTGTIL 668
F L+ Y+ + E +P + V V+ D D + +NG F I TG I
Sbjct: 3404 FTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQIT 3463
Query: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
+ DRE Y + AVD G P + + + + D NDN P +T S +
Sbjct: 3464 VTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLT----VSEGEVME 3519
Query: 729 QTRLGETVSQVAAEDFDSGVN-AELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGL 787
R G V + + D D N Y + P + S +G ++ +EI+R
Sbjct: 3520 NKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIAD 3579
Query: 788 HRLVVKVSDRGKPPRYGTALVHLYV 812
L V D G P T VH+ V
Sbjct: 3580 FYLSVVTKDSGVPQMSSTGTVHITV 3604
Score = 209 bits (532), Expect = 1e-53
Identities = 173/565 (30%), Positives = 270/565 (47%), Gaps = 40/565 (7%)
Query: 156 IEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQE 215
I V + N +TP F+ ++ IPE+ +IGS+ A DRDA NG+ Y + +G E +
Sbjct: 3077 ITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNE-EG 3135
Query: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTND 275
+F + + L + LD E +++TI DGG R + V V+D ND
Sbjct: 3136 IFAINSSTGI------LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
Query: 276 NAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRN 335
N+P F Y + EN+P G +VI + A D+D G NA I YT + L +D N
Sbjct: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS---DLFVIDPN 3246
Query: 336 TGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLV 395
TG+IT QG +D E + +V A + + + A V + +K N+ P R + +
Sbjct: 3247 TGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVP----RFVSKL 3302
Query: 396 THQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVP---FQLRQASETGSDS 452
+ + ISE + T V V SDRD G + V ++ G+ FQ+ +
Sbjct: 3303 YYFE----ISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQI---------N 3349
Query: 453 KKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTN--SLKVQVVDVNDNAPVFTQSV 510
KK + + LD EK + +++++A + G+ + + ++ V V+D ND P+FT ++
Sbjct: 3350 KKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNI 3408
Query: 511 TEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKTSL 570
V E G + ++A D+DS + G F+I+P+TG+I V L
Sbjct: 3409 YSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAEL 3468
Query: 571 DREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSP 630
DRE Y L V+A D G+PS G+A++LV + D NDN P ML+ VMEN +
Sbjct: 3469 DRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP--MLTVSEGEVMENKRPGTL 3526
Query: 631 VGMVTVIDGD----KGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLK 686
V + D D +G LS F + G + ++ DREQ + + +
Sbjct: 3527 VMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVV 3585
Query: 687 AVDGGVPPRSAYVGVTINVLDENDN 711
D GVP S+ V I V+D+NDN
Sbjct: 3586 TKDSGVPQMSSTGTVHITVIDQNDN 3610
>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
[Homo sapiens]
Length = 1007
Score = 342 bits (878), Expect = 1e-93
Identities = 240/693 (34%), Positives = 359/693 (51%), Gaps = 56/693 (8%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFP----DVGHLYKL 92
LLLP LL LLLLL P P A+++ Y VPEEQ P L+G++A G G L
Sbjct: 24 LLLP--LLLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRIN 80
Query: 93 EVGAP---YLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSP 149
+GAP YL +D +G +F E IDRE L E + + C+L EV + V +
Sbjct: 81 HLGAPSPRYLELDLTSGALFVNER-IDREALCEQRPR-----CLLSLEVLAHNPVAVSAV 134
Query: 150 RLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQA 209
++E+ DINDN+P F P L + E+ G+ F I A D D G N V +YEL
Sbjct: 135 -----EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSP 189
Query: 210 GPEAQELFGLQVAEDQEE-KQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
E F L + QE K +L++ LDRE+ + L + DGG P R+ +A + V
Sbjct: 190 S----EHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISV 245
Query: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-APEVVR 327
VLDTNDN+P F++ +Y +L E+SP G V+++ A+D D+G+N E+ Y+ + R
Sbjct: 246 RVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRER 305
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
+L +D +TG + V G +D E+ S+ + V A DRG P + +V+V + D+NDNAP +
Sbjct: 306 QLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEV 365
Query: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
+ D + + E+ T VA++ V+D+D G N V+ + +PF+L
Sbjct: 366 VL--------TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGN 417
Query: 448 TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFT 507
+ Y L + PLD E+V Y I + A D G P L+S +LKV++ D+NDN P F
Sbjct: 418 S-------YTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFL 470
Query: 508 QSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGL-----FTISPETG 562
+ + ENN PG ++ + A+D D NAE+ YSL E +GL +I+ +G
Sbjct: 471 EDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL-LEREIQGLPVTSYVSINSASG 529
Query: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM--LSGYNFS 620
+ S D E+ + + V A D+GSP L T T V V+D ND+ P + S + +
Sbjct: 530 SLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSA 589
Query: 621 VMENMPALSPVG----MVTVIDGDKGENAQV--QLSVEQDNGDFVIQNGTGTILSSLSFD 674
E +P +P G V +D D G+NA + L+ D F ++ TG I ++
Sbjct: 590 AFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMG 649
Query: 675 REQQSTYTFQLKAVDGGVPPRSAYVGVTINVLD 707
E ST+ + D G P SA V +T+ V+D
Sbjct: 650 DESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
Score = 224 bits (570), Expect = 5e-58
Identities = 172/563 (30%), Positives = 264/563 (46%), Gaps = 43/563 (7%)
Query: 259 PRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYT 318
P A SA+ V +LD NDN+P+F RP+Y+ ++SE+ G A D D GAN+ Y
Sbjct: 128 PVAVSAV-EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYE 186
Query: 319 FHQAPEVVRRLLRLDRNTGLI--TVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVT 376
+ L L N+ ++ ++ +DRE + + A D G +S AQ+ V
Sbjct: 187 LSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVR 246
Query: 377 VKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG 436
V D NDN+P + + ED T V + SD DEG N G
Sbjct: 247 VLDTNDNSPAFD--------QSTYRVQLREDSPPGTLVVKLNASDPDEGSN--------G 290
Query: 437 DVPFQLRQASETGSDSKKKYFLQTTTP-------LDYEKVKDYTIEIVAVDSGNPPLSST 489
++ + L +S T ++ + + +T LDYE+ Y I + A D G P++
Sbjct: 291 ELRYSL--SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGH 348
Query: 490 NSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPE- 548
+ V +VDVNDNAP + PEN P ++A ++ +D DSG N ++ LE
Sbjct: 349 CKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATL 408
Query: 549 PAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDN 608
P F S + V LDRE+ Y + V A D G P L T+ V + D NDN
Sbjct: 409 PFRLNGFGNSYT---LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDN 465
Query: 609 DPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFV-------IQ 661
P F+ Y+ + EN + V D D+ ENA+V S+ + + I
Sbjct: 466 PPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSIN 525
Query: 662 NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNT 721
+ +G++ + SFD E+ + ++A D G PP S+ V + V+D ND+AP+I P++T
Sbjct: 526 SASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST 585
Query: 722 SHKL---LTPQTR-LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLE 777
+ + P+T G V++V A D DSG NA L Y +A + LF++ H+G I
Sbjct: 586 NSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTT 645
Query: 778 KEIERRHHGLHRLVVKVSDRGKP 800
+++ L V V D G+P
Sbjct: 646 RKMGDESGSTFNLTVVVRDNGEP 668
Score = 200 bits (508), Expect = 8e-51
Identities = 158/502 (31%), Positives = 235/502 (46%), Gaps = 37/502 (7%)
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLR------FSVLAKDRGTNPKSARAQVVVTVKDMN 381
R L LD +G + V +DRE L R VLA NP + A V V + D+N
Sbjct: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAH----NPVAVSA-VEVEILDIN 142
Query: 382 DNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ 441
DN+P L +SE VA + D D G N+ T ++ F+
Sbjct: 143 DNSPRFPRPNYQL--------QVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
Query: 442 LRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
L + ++ K L LD E+ + + + AVD G P S T + V+V+D ND
Sbjct: 195 LDL--KPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTND 252
Query: 502 NAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA--AKGLFTISP 559
N+P F QS V E++ PG ++ ++ ASD D GSN EL YSL + + LF+I
Sbjct: 253 NSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDA 312
Query: 560 ETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNF 619
TGE++V LD E+ SY++ V A DRG + G VLV+++D NDN P+ +L+
Sbjct: 313 STGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYS 372
Query: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTG---TILSSLSFDRE 676
V EN + V +++V D D G N +V L +E + NG G T++ S DRE
Sbjct: 373 PVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL--NGFGNSYTLVVSGPLDRE 430
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GET 735
+ + Y + A DGG+P ++ + + + D NDN P S+ + + L G
Sbjct: 431 RVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFL---EDSYSIYIQENNLPGVL 487
Query: 736 VSQVAAEDFDSGVNAELIYSIAGGNPYGL-----FQIGSHSGAITLEKEIERRHHGLHRL 790
+ V A D D NAE+ YS+ GL I S SG++ + +
Sbjct: 488 LCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFV 547
Query: 791 VVKVSDRGKPPRYGTALVHLYV 812
V+ D+G PP T ++YV
Sbjct: 548 TVEAQDKGSPPLSSTVTANVYV 569
Score = 48.1 bits (113), Expect = 5e-05
Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
Query: 697 AYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVA------AEDFDSGVNA 750
A V + +LD NDN+P P+ Q ++ E+V+ A A+D D G N+
Sbjct: 130 AVSAVEVEILDINDNSPRFPRPNY--------QLQVSESVAPGARFHIESAQDPDVGANS 181
Query: 751 ELIYSIAGGNPYGL----FQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806
Y ++ + L Q S + L K ++R LH LV+ D G P R GTA
Sbjct: 182 VQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTA 241
Query: 807 LVHLYVNETLAN 818
+ + V +T N
Sbjct: 242 QISVRVLDTNDN 253
>gi|14165431 protocadherin alpha subfamily C, 2 isoform 2 precursor
[Homo sapiens]
Length = 884
Score = 342 bits (878), Expect = 1e-93
Identities = 240/693 (34%), Positives = 359/693 (51%), Gaps = 56/693 (8%)
Query: 37 LLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFP----DVGHLYKL 92
LLLP LL LLLLL P P A+++ Y VPEEQ P L+G++A G G L
Sbjct: 24 LLLP--LLLLLLLLLPGPA-ASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRIN 80
Query: 93 EVGAP---YLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSP 149
+GAP YL +D +G +F E IDRE L E + + C+L EV + V +
Sbjct: 81 HLGAPSPRYLELDLTSGALFVNER-IDREALCEQRPR-----CLLSLEVLAHNPVAVSAV 134
Query: 150 RLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQA 209
++E+ DINDN+P F P L + E+ G+ F I A D D G N V +YEL
Sbjct: 135 -----EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSP 189
Query: 210 GPEAQELFGLQVAEDQEE-KQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
E F L + QE K +L++ LDRE+ + L + DGG P R+ +A + V
Sbjct: 190 S----EHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISV 245
Query: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQ-APEVVR 327
VLDTNDN+P F++ +Y +L E+SP G V+++ A+D D+G+N E+ Y+ + R
Sbjct: 246 RVLDTNDNSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRER 305
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
+L +D +TG + V G +D E+ S+ + V A DRG P + +V+V + D+NDNAP +
Sbjct: 306 QLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEV 365
Query: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
+ D + + E+ T VA++ V+D+D G N V+ + +PF+L
Sbjct: 366 VL--------TDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRLNGFGN 417
Query: 448 TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFT 507
+ Y L + PLD E+V Y I + A D G P L+S +LKV++ D+NDN P F
Sbjct: 418 S-------YTLVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFL 470
Query: 508 QSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGL-----FTISPETG 562
+ + ENN PG ++ + A+D D NAE+ YSL E +GL +I+ +G
Sbjct: 471 EDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSL-LEREIQGLPVTSYVSINSASG 529
Query: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM--LSGYNFS 620
+ S D E+ + + V A D+GSP L T T V V+D ND+ P + S + +
Sbjct: 530 SLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTSTNSSA 589
Query: 621 VMENMPALSPVG----MVTVIDGDKGENAQV--QLSVEQDNGDFVIQNGTGTILSSLSFD 674
E +P +P G V +D D G+NA + L+ D F ++ TG I ++
Sbjct: 590 AFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTTRKMG 649
Query: 675 REQQSTYTFQLKAVDGGVPPRSAYVGVTINVLD 707
E ST+ + D G P SA V +T+ V+D
Sbjct: 650 DESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682
Score = 224 bits (570), Expect = 5e-58
Identities = 172/563 (30%), Positives = 264/563 (46%), Gaps = 43/563 (7%)
Query: 259 PRASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYT 318
P A SA+ V +LD NDN+P+F RP+Y+ ++SE+ G A D D GAN+ Y
Sbjct: 128 PVAVSAV-EVEILDINDNSPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYE 186
Query: 319 FHQAPEVVRRLLRLDRNTGLI--TVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVT 376
+ L L N+ ++ ++ +DRE + + A D G +S AQ+ V
Sbjct: 187 LSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVR 246
Query: 377 VKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAG 436
V D NDN+P + + ED T V + SD DEG N G
Sbjct: 247 VLDTNDNSPAFD--------QSTYRVQLREDSPPGTLVVKLNASDPDEGSN--------G 290
Query: 437 DVPFQLRQASETGSDSKKKYFLQTTTP-------LDYEKVKDYTIEIVAVDSGNPPLSST 489
++ + L +S T ++ + + +T LDYE+ Y I + A D G P++
Sbjct: 291 ELRYSL--SSYTSDRERQLFSIDASTGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGH 348
Query: 490 NSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPE- 548
+ V +VDVNDNAP + PEN P ++A ++ +D DSG N ++ LE
Sbjct: 349 CKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATL 408
Query: 549 PAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDN 608
P F S + V LDRE+ Y + V A D G P L T+ V + D NDN
Sbjct: 409 PFRLNGFGNSYT---LVVSGPLDRERVAVYNITVTATDGGIPQLTSLRTLKVEISDINDN 465
Query: 609 DPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFV-------IQ 661
P F+ Y+ + EN + V D D+ ENA+V S+ + + I
Sbjct: 466 PPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSIN 525
Query: 662 NGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNT 721
+ +G++ + SFD E+ + ++A D G PP S+ V + V+D ND+AP+I P++T
Sbjct: 526 SASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTANVYVVDMNDHAPHILYPTST 585
Query: 722 SHKL---LTPQTR-LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLE 777
+ + P+T G V++V A D DSG NA L Y +A + LF++ H+G I
Sbjct: 586 NSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHLAQTSDLDLFKVELHTGEIRTT 645
Query: 778 KEIERRHHGLHRLVVKVSDRGKP 800
+++ L V V D G+P
Sbjct: 646 RKMGDESGSTFNLTVVVRDNGEP 668
Score = 200 bits (508), Expect = 8e-51
Identities = 158/502 (31%), Positives = 235/502 (46%), Gaps = 37/502 (7%)
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLR------FSVLAKDRGTNPKSARAQVVVTVKDMN 381
R L LD +G + V +DRE L R VLA NP + A V V + D+N
Sbjct: 88 RYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAH----NPVAVSA-VEVEILDIN 142
Query: 382 DNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ 441
DN+P L +SE VA + D D G N+ T ++ F+
Sbjct: 143 DNSPRFPRPNYQL--------QVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFE 194
Query: 442 LRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
L + ++ K L LD E+ + + + AVD G P S T + V+V+D ND
Sbjct: 195 LDL--KPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTND 252
Query: 502 NAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPA--AKGLFTISP 559
N+P F QS V E++ PG ++ ++ ASD D GSN EL YSL + + LF+I
Sbjct: 253 NSPAFDQSTYRVQLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDA 312
Query: 560 ETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNF 619
TGE++V LD E+ SY++ V A DRG + G VLV+++D NDN P+ +L+
Sbjct: 313 STGEVRVIGGLDYEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYS 372
Query: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTG---TILSSLSFDRE 676
V EN + V +++V D D G N +V L +E + NG G T++ S DRE
Sbjct: 373 PVPENATPNTIVAVLSVNDQDSGPNRKVSLGLEATLPFRL--NGFGNSYTLVVSGPLDRE 430
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRL-GET 735
+ + Y + A DGG+P ++ + + + D NDN P S+ + + L G
Sbjct: 431 RVAVYNITVTATDGGIPQLTSLRTLKVEISDINDNPPSFL---EDSYSIYIQENNLPGVL 487
Query: 736 VSQVAAEDFDSGVNAELIYSIAGGNPYGL-----FQIGSHSGAITLEKEIERRHHGLHRL 790
+ V A D D NAE+ YS+ GL I S SG++ + +
Sbjct: 488 LCTVQATDPDEKENAEVTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFV 547
Query: 791 VVKVSDRGKPPRYGTALVHLYV 812
V+ D+G PP T ++YV
Sbjct: 548 TVEAQDKGSPPLSSTVTANVYV 569
Score = 48.1 bits (113), Expect = 5e-05
Identities = 39/132 (29%), Positives = 59/132 (44%), Gaps = 18/132 (13%)
Query: 697 AYVGVTINVLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVA------AEDFDSGVNA 750
A V + +LD NDN+P P+ Q ++ E+V+ A A+D D G N+
Sbjct: 130 AVSAVEVEILDINDNSPRFPRPNY--------QLQVSESVAPGARFHIESAQDPDVGANS 181
Query: 751 ELIYSIAGGNPYGL----FQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806
Y ++ + L Q S + L K ++R LH LV+ D G P R GTA
Sbjct: 182 VQTYELSPSEHFELDLKPLQENSKVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTA 241
Query: 807 LVHLYVNETLAN 818
+ + V +T N
Sbjct: 242 QISVRVLDTNDN 253
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 340 bits (872), Expect = 5e-93
Identities = 252/709 (35%), Positives = 359/709 (50%), Gaps = 73/709 (10%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDV-----GHLYKLEVGA 96
++L L LL G +++ Y V EEQ T +G++A D G G
Sbjct: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
Query: 97 PYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQI 156
PYL ++ +TG ++ E IDRE + C+ Q P C+L EV + + ++ L + +I
Sbjct: 62 PYLDLNLETGVLYVNE-KIDREQI--CK-QSPS--CVLHLEVFLENPLE-----LFQVEI 110
Query: 157 EVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQEL 216
EV DINDN P+F P +T+ I E+ G+ FP+ A D D G N + YE+
Sbjct: 111 EVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN----SY 166
Query: 217 FGLQV-AEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGS----------------PP 259
F L V + + +L++ LDRE+ + + DGG PP
Sbjct: 167 FSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPP 226
Query: 260 ---RASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIE 316
R +ALL + VLD+NDN P F++P Y L ENSP G VIQ+ A D D+G N E+
Sbjct: 227 QQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVV 286
Query: 317 YTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
Y+F H +P R L L TG + V G +D E+ + V AKD G N A +V+
Sbjct: 287 YSFSSHISPRA-RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVL 345
Query: 375 VTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV 434
V V D NDNAP I + +SE A T VAL V+DRD EN V C +
Sbjct: 346 VRVLDANDNAPEISFSTV--------KEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL 397
Query: 435 AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKV 494
GDVPF+L+ S K Y + T PLD E YT+ +VA D G P LS++ S++V
Sbjct: 398 LGDVPFRLK------SSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQV 451
Query: 495 QVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYS-LEPEPAAKG 553
QV DVNDNAP F+Q V +V ENN PG I ++A+D D G+NA+L YS LE +
Sbjct: 452 QVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMS 511
Query: 554 LFT---ISPETGEIQVKTSLDREQRESYELKVVAADRGSP-SLQGTATVLVNVLDCNDND 609
+FT I+ E G + S D EQ + + +V A D GSP +L G ATV + ++D NDN
Sbjct: 512 VFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNA 571
Query: 610 PKFM--LSGYNFS-VMENMPALSPVG----MVTVIDGDKGENAQVQLSVEQDN--GDFVI 660
P + L G N + E +P + G V +D D GENA++ S+ + N F +
Sbjct: 572 PAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRM 631
Query: 661 QNGTGTILSS--LSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLD 707
TG + ++ + R+ Q Y ++ D G PP S+ + + ++D
Sbjct: 632 DWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 226 bits (575), Expect = 1e-58
Identities = 245/967 (25%), Positives = 388/967 (40%), Gaps = 167/967 (17%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
+ + VLD NDN P F P E+SE++ G A D D G N+ +Y
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-----T 162
Query: 326 VRRLLRLDRNT-------GLITVQGPVDREDLSTLRFSVLAKDRG--------------- 363
LD T + ++ P+DRE + R+ + A D G
Sbjct: 163 PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222
Query: 364 ----TNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQV 419
++ A + + V D NDN P + ++ E+ T V +
Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFD--------QPVYTVSLPENSPPGTLVIQLNA 274
Query: 420 SDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAV 479
+D DEG+N V + + +A E S + L+ + LDYE+ Y + + A
Sbjct: 275 TDPDEGQNGEVVYSFSSHIS---PRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAK 331
Query: 480 DSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNA 539
D G + + + V+V+D NDNAP + S + A E PG V+A + +D DS N
Sbjct: 332 DLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENG 391
Query: 540 ELVYSL------EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQ 593
++ L + + K +TI E LDRE +SY L VVA DRG P+L
Sbjct: 392 QVQCELLGDVPFRLKSSFKNYYTIVTEA-------PLDREAGDSYTLTVVARDRGEPALS 444
Query: 594 GTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVE- 652
+ ++ V V D NDN P+F Y+ V EN + + V+ D D+G NAQ+ S+
Sbjct: 445 TSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILE 504
Query: 653 -QDNGDFV-----IQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVL 706
Q G V I + G + + SFD EQ ++FQ++A D G P A T+N+L
Sbjct: 505 CQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAG-NATVNIL 563
Query: 707 --DENDNAPYITAP-----SNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGG 759
D+NDNAP I AP + ++L G +++VAA D D G NA L YSI G
Sbjct: 564 IVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRG 623
Query: 760 NPYGLFQIGSHSGAITLEKEI--ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLA 817
N LF++ +G + + + +R + LV++V D G+PP TA
Sbjct: 624 NEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTA----------- 672
Query: 818 NRTLLETLLGHSLDTP--LDIDIAGDPEYERSKQRG--------NILFGVVAGVVAVALL 867
TL+ L+ +++ G E++R + G ++ + G V+ L
Sbjct: 673 --TLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFL 730
Query: 868 IALAVLVRYCRQREAKSGYQAGKKE-TKDLYAPKPSGKASKGNKSKGKKSKSPKPVKPVE 926
+A+ VL C++ + + Y + G G +++ +K K K
Sbjct: 731 LAMIVLAVRCQKEKKLNIYTCLASDCCLCCCCCGGGGSTCCGRQARARKKKLSK------ 784
Query: 927 DEDEAGLQKSLKFNLMSDAPGDSPRIHLPLNYPPGSPDLGRHYRSNSPLPSIQLQPQSPS 986
+ S+ P + ++ P+ G G H+ + + + L P+S
Sbjct: 785 --------SDIMLVQSSNVPSNPAQV--PIEESGG---FGSHHHNQNYCYQVCLTPESAK 831
Query: 987 --------ASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDYSYRTNPPKYPSKQLPH-- 1036
S + P V TG T + S+ S +N K+ +L +
Sbjct: 832 TDLMFLKPCSPSRSTDTEHNPCGAIV-TG-YTDQQPDIISNGSILSNETKHQRAELSYLV 889
Query: 1037 ---RRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLALPEDHYERTT 1093
RRV SA +E++ SSK S
Sbjct: 890 DRPRRVNSSA-------------------FQEADIVSSKDSG-----------------H 913
Query: 1094 PDGSIGEMEHPENDLRPLPDVAMTGTCTRECSEFGHSDTCWMPGQSSPSRRTKSSALKLS 1153
D G+ +H + + + CT EC GHSD CWMP PS +++ + +
Sbjct: 914 GDSEQGDSDHDATNRAQSAGMDLFSNCTEECKALGHSDRCWMP-SFVPSDGRQAADYRSN 972
Query: 1154 TFVPYQD 1160
VP D
Sbjct: 973 LHVPGMD 979
Score = 184 bits (466), Expect = 6e-46
Identities = 157/525 (29%), Positives = 226/525 (43%), Gaps = 44/525 (8%)
Query: 319 FHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS-VLAKDRGTNPKSARAQVVVTV 377
F P L L+ TG++ V +DRE + S VL + QV + V
Sbjct: 53 FQTVPNSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEV 112
Query: 378 KDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGD 437
D+NDN P+ D ISE T L D D G N+ + +
Sbjct: 113 LDINDNPPSFP--------EPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN 164
Query: 438 VPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGN-------------- 483
F L +T D + L PLD E+ + + AVD G
Sbjct: 165 SYFSLDV--QTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222
Query: 484 --PPL---SSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
PP + T L ++V+D NDN P F Q V V+ PEN+ PG ++ ++ A+D D G N
Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQN 282
Query: 539 AELVYSLEPE--PAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTA 596
E+VYS P A+ LF +SP TG ++V LD E+ Y++ V A D G ++
Sbjct: 283 GEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHC 342
Query: 597 TVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG 656
VLV VLD NDN P+ S +V E + V + +V D D EN QVQ + D
Sbjct: 343 KVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDV- 401
Query: 657 DFVIQNGTG---TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAP 713
F +++ TI++ DRE +YT + A D G P S + + V D NDNAP
Sbjct: 402 PFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAP 461
Query: 714 YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYS-----IAGGNPYGLFQIG 768
+ P + +T G + V+A D D G NA+L YS I G + + I
Sbjct: 462 RFSQPVYDVY--VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSIN 519
Query: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRY-GTALVHLYV 812
S +G + + + V+ D G P G A V++ +
Sbjct: 520 SENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILI 564
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 340 bits (872), Expect = 5e-93
Identities = 252/709 (35%), Positives = 359/709 (50%), Gaps = 73/709 (10%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDV-----GHLYKLEVGA 96
++L L LL G +++ Y V EEQ T +G++A D G G
Sbjct: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLDITKLSARGFQTVPNSRT 61
Query: 97 PYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQI 156
PYL ++ +TG ++ E IDRE + C+ Q P C+L EV + + ++ L + +I
Sbjct: 62 PYLDLNLETGVLYVNE-KIDREQI--CK-QSPS--CVLHLEVFLENPLE-----LFQVEI 110
Query: 157 EVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQEL 216
EV DINDN P+F P +T+ I E+ G+ FP+ A D D G N + YE+
Sbjct: 111 EVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN----SY 166
Query: 217 FGLQV-AEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGS----------------PP 259
F L V + + +L++ LDRE+ + + DGG PP
Sbjct: 167 FSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPP 226
Query: 260 ---RASSALLRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIE 316
R +ALL + VLD+NDN P F++P Y L ENSP G VIQ+ A D D+G N E+
Sbjct: 227 QQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVV 286
Query: 317 YTF--HQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVV 374
Y+F H +P R L L TG + V G +D E+ + V AKD G N A +V+
Sbjct: 287 YSFSSHISPRA-RELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVL 345
Query: 375 VTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVV 434
V V D NDNAP I + +SE A T VAL V+DRD EN V C +
Sbjct: 346 VRVLDANDNAPEISFSTV--------KEAVSEGAAPGTVVALFSVTDRDSEENGQVQCEL 397
Query: 435 AGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKV 494
GDVPF+L+ S K Y + T PLD E YT+ +VA D G P LS++ S++V
Sbjct: 398 LGDVPFRLK------SSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQV 451
Query: 495 QVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYS-LEPEPAAKG 553
QV DVNDNAP F+Q V +V ENN PG I ++A+D D G+NA+L YS LE +
Sbjct: 452 QVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMS 511
Query: 554 LFT---ISPETGEIQVKTSLDREQRESYELKVVAADRGSP-SLQGTATVLVNVLDCNDND 609
+FT I+ E G + S D EQ + + +V A D GSP +L G ATV + ++D NDN
Sbjct: 512 VFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNA 571
Query: 610 PKFM--LSGYNFS-VMENMPALSPVG----MVTVIDGDKGENAQVQLSVEQDN--GDFVI 660
P + L G N + E +P + G V +D D GENA++ S+ + N F +
Sbjct: 572 PAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRM 631
Query: 661 QNGTGTILSS--LSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLD 707
TG + ++ + R+ Q Y ++ D G PP S+ + + ++D
Sbjct: 632 DWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 211 bits (536), Expect = 5e-54
Identities = 192/676 (28%), Positives = 296/676 (43%), Gaps = 96/676 (14%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
+ + VLD NDN P F P E+SE++ G A D D G N+ +Y
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-----T 162
Query: 326 VRRLLRLDRNT-------GLITVQGPVDREDLSTLRFSVLAKDRG--------------- 363
LD T + ++ P+DRE + R+ + A D G
Sbjct: 163 PNSYFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222
Query: 364 ----TNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQV 419
++ A + + V D NDN P + ++ E+ T V +
Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFD--------QPVYTVSLPENSPPGTLVIQLNA 274
Query: 420 SDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAV 479
+D DEG+N V + + +A E S + L+ + LDYE+ Y + + A
Sbjct: 275 TDPDEGQNGEVVYSFSSHIS---PRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAK 331
Query: 480 DSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNA 539
D G + + + V+V+D NDNAP + S + A E PG V+A + +D DS N
Sbjct: 332 DLGPNAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENG 391
Query: 540 ELVYSL------EPEPAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQ 593
++ L + + K +TI E LDRE +SY L VVA DRG P+L
Sbjct: 392 QVQCELLGDVPFRLKSSFKNYYTIVTEA-------PLDREAGDSYTLTVVARDRGEPALS 444
Query: 594 GTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVE- 652
+ ++ V V D NDN P+F Y+ V EN + + V+ D D+G NAQ+ S+
Sbjct: 445 TSKSIQVQVSDVNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILE 504
Query: 653 -QDNGDFV-----IQNGTGTILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVL 706
Q G V I + G + + SFD EQ ++FQ++A D G P A T+N+L
Sbjct: 505 CQIQGMSVFTYVSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAG-NATVNIL 563
Query: 707 --DENDNAPYITAP-----SNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGG 759
D+NDNAP I AP + ++L G +++VAA D D G NA L YSI G
Sbjct: 564 IVDQNDNAPAIVAPLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRG 623
Query: 760 NPYGLFQIGSHSGAITLEKEI--ERRHHGLHRLVVKVSDRGKPPRYGTALVHLYVNETLA 817
N LF++ +G + + + +R + LV++V D G+PP TA
Sbjct: 624 NEMNLFRMDWRTGELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTA----------- 672
Query: 818 NRTLLETLLGHSLDTP--LDIDIAGDPEYERSKQRG--------NILFGVVAGVVAVALL 867
TL+ L+ +++ G E++R + G ++ + G V+ L
Sbjct: 673 --TLVVQLVDGAVEPQGGGGSGGGGSGEHQRPSRSGGGETSLDLTLILIIALGSVSFIFL 730
Query: 868 IALAVLVRYCRQREAK 883
+A+ VL C Q+E K
Sbjct: 731 LAMIVLAVRC-QKEKK 745
Score = 184 bits (466), Expect = 6e-46
Identities = 157/525 (29%), Positives = 226/525 (43%), Gaps = 44/525 (8%)
Query: 319 FHQAPEVVRRLLRLDRNTGLITVQGPVDREDLSTLRFS-VLAKDRGTNPKSARAQVVVTV 377
F P L L+ TG++ V +DRE + S VL + QV + V
Sbjct: 53 FQTVPNSRTPYLDLNLETGVLYVNEKIDREQICKQSPSCVLHLEVFLENPLELFQVEIEV 112
Query: 378 KDMNDNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGD 437
D+NDN P+ D ISE T L D D G N+ + +
Sbjct: 113 LDINDNPPSFP--------EPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEITPN 164
Query: 438 VPFQLRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGN-------------- 483
F L +T D + L PLD E+ + + AVD G
Sbjct: 165 SYFSLDV--QTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGA 222
Query: 484 --PPL---SSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSN 538
PP + T L ++V+D NDN P F Q V V+ PEN+ PG ++ ++ A+D D G N
Sbjct: 223 GLPPQQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQN 282
Query: 539 AELVYSLEPE--PAAKGLFTISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTA 596
E+VYS P A+ LF +SP TG ++V LD E+ Y++ V A D G ++
Sbjct: 283 GEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHC 342
Query: 597 TVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNG 656
VLV VLD NDN P+ S +V E + V + +V D D EN QVQ + D
Sbjct: 343 KVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQCELLGDV- 401
Query: 657 DFVIQNGTG---TILSSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAP 713
F +++ TI++ DRE +YT + A D G P S + + V D NDNAP
Sbjct: 402 PFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNAP 461
Query: 714 YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYS-----IAGGNPYGLFQIG 768
+ P + +T G + V+A D D G NA+L YS I G + + I
Sbjct: 462 RFSQPVYDVY--VTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSIN 519
Query: 769 SHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRY-GTALVHLYV 812
S +G + + + V+ D G P G A V++ +
Sbjct: 520 SENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILI 564
>gi|11036656 protocadherin beta 7 precursor [Homo sapiens]
Length = 793
Score = 340 bits (871), Expect = 6e-93
Identities = 238/703 (33%), Positives = 355/703 (50%), Gaps = 53/703 (7%)
Query: 35 QRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKL-- 92
+R + +L L + L S A + Y V EE T + +LA D G VG L
Sbjct: 6 ERAVQKRQVLFLCVFLGMSWAGAEPLRYFVAEETERGTFLTNLAKDLGL-GVGELRARGT 64
Query: 93 ----EVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGS 148
+ L + TGD+ E +DRE L C P +PC+L F++ + Q
Sbjct: 65 RIVSDQNMQILLLSSLTGDLLLNE-KLDREEL--CG---PREPCVLPFQLLLEKPFQ--- 115
Query: 149 PRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQ 208
+ ++ V+DIND+ P F I+L I E+T G+ F + A D D G N +++Y +
Sbjct: 116 --IFRAELWVRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTIS 173
Query: 209 AGPEAQELFGLQVAEDQEEK-QPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLR 267
P A F + V + E P+L++ LDRE + LT+ DGGSPPR+ +AL+R
Sbjct: 174 --PNAY--FHINVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVR 229
Query: 268 VTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVR 327
+ VLD NDNAP F R Y+ ++ ENSP+G V+ V A D D G+N EI Y F A E +
Sbjct: 230 ILVLDVNDNAPDFVRSLYKVQVPENSPVGSMVVSVSARDLDTGSNGEIAYAFSYATERIL 289
Query: 328 RLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTI 387
+ +++ +G + ++ +D E + T ++ AKD G S + VVV V D+NDN P +
Sbjct: 290 KTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGG--GLSGKCTVVVDVTDINDNRPEL 347
Query: 388 EIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASE 447
+ + + I+E+ + ET VA+ ++ DRD G N C + DVPF L+ + E
Sbjct: 348 LLSSL--------TSPIAEN-SPETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVE 398
Query: 448 TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFT 507
Y L T PLD E+ +Y I I D G P L + +++ V V DVNDNAP FT
Sbjct: 399 ------NFYTLVTEKPLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFT 452
Query: 508 QSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL----EPEPAAKGLFTISPETGE 563
Q+ + ENN P I ++A+D DSG+NA+++YSL +P L +I+ + G
Sbjct: 453 QTSYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGH 512
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSV-- 621
+ SLD E +++E +V A DRGSP+L A V V VLD NDN P + N S
Sbjct: 513 LFALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPC 572
Query: 622 MENMPALSPVG----MVTVIDGDKGENA--QVQLSVEQDNGDFVIQNGTGTILSSLSFDR 675
E +P + G V +DGD G+NA QL + G F + G + ++
Sbjct: 573 TEPLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSE 632
Query: 676 EQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP 718
+ + D G PPRSA + + ++D + PY+ P
Sbjct: 633 RDAAKQRLVVLVKDNGEPPRSATATLHVLLVD-GFSQPYLRLP 674
Score = 224 bits (570), Expect = 5e-58
Identities = 174/566 (30%), Positives = 255/566 (45%), Gaps = 53/566 (9%)
Query: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRL 329
V D ND+AP F ++ E++ G + + A DSD G N+ YT +P +
Sbjct: 123 VRDINDHAPVFLDREISLKILESTTPGAAFLLESAQDSDVGTNSLSNYTI--SPNAYFHI 180
Query: 330 LRLDRNTGLI----TVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 385
D G I + +DRE++ ++ A D G+ P+S A V + V D+NDNAP
Sbjct: 181 NVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILVLDVNDNAP 240
Query: 386 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 445
+R + V + E+ + V V D D G N G++ + A
Sbjct: 241 DF-VRSLYKV-------QVPENSPVGSMVVSVSARDLDTGSN--------GEIAYAFSYA 284
Query: 446 SE----TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
+E T + L LDYE ++ YT+ I A D G LS ++ V V D+ND
Sbjct: 285 TERILKTFQINPTSGSLHLKAQLDYEAIQTYTLTIQAKDGGG--LSGKCTVVVDVTDIND 342
Query: 502 NAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPE------PAAKGLF 555
N P S EN+ P V+A D DSG+N + V S++ + P+ + +
Sbjct: 343 NRPELLLSSLTSPIAENS-PETVVAVFRIRDRDSGNNGKTVCSIQDDVPFILKPSVENFY 401
Query: 556 TISPETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLS 615
T+ E LDRE+ Y + + D G+P L+ + V V D NDN P F +
Sbjct: 402 TLVTEK-------PLDRERNTEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQT 454
Query: 616 GYNFSVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFV-------IQNGTGTIL 668
Y V EN P+G V+ D D G NAQV S+ + I G +
Sbjct: 455 SYTLFVRENNSPALPIGSVSATDRDSGTNAQVIYSLLPSQDPHLPLASLVSINADNGHLF 514
Query: 669 SSLSFDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP-SNTSHKLLT 727
+ S D E + F++ A D G P S+ V + VLD NDN+P++ P N+S
Sbjct: 515 ALRSLDYEALQAFEFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNSSAPCTE 574
Query: 728 PQTRLGET---VSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRH 784
P R E V++V A D DSG NA L Y + GLF + +H+G + + + R
Sbjct: 575 PLPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERD 634
Query: 785 HGLHRLVVKVSDRGKPPRYGTALVHL 810
RLVV V D G+PPR TA +H+
Sbjct: 635 AAKQRLVVLVKDNGEPPRSATATLHV 660
Score = 40.8 bits (94), Expect = 0.008
Identities = 36/115 (31%), Positives = 50/115 (43%), Gaps = 12/115 (10%)
Query: 705 VLDENDNAPYITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGL 764
V D ND+AP + S K+L T G +A+D D G N+ Y+I+ P
Sbjct: 123 VRDINDHAP-VFLDREISLKILESTTP-GAAFLLESAQDSDVGTNSLSNYTIS---PNAY 177
Query: 765 FQIGSHSGA-------ITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
F I H + L + ++R L + D G PPR GTALV + V
Sbjct: 178 FHINVHDSGEGNIYPELVLNQVLDREEIPEFSLTLTALDGGSPPRSGTALVRILV 232
>gi|14270505 protocadherin gamma subfamily B, 5 isoform 2 precursor
[Homo sapiens]
Length = 818
Score = 338 bits (868), Expect = 1e-92
Identities = 232/685 (33%), Positives = 352/685 (51%), Gaps = 56/685 (8%)
Query: 31 GPGGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHL- 89
G G+ LP + L LL L P+ R Y++PEE P +++G+LA D GF V L
Sbjct: 6 GELGRAERLPVLFLFLLSLFCPALCEQIR--YRIPEEMPKGSVVGNLATDLGF-SVQELP 62
Query: 90 -YKLEVGA--PYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQN 146
KL V + PY V ++G++ + + +DRE E + P C LEFE V
Sbjct: 63 TRKLRVSSEKPYFTVSAESGELLVS-SRLDRE---EICGKKPA--CALEFEA-----VAE 111
Query: 147 GSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
+E++DIND+TP F L I E+ G+ F + +A D D G N + Y+
Sbjct: 112 NPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYK 171
Query: 207 LQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSAL 265
L P F L + E Q+ K P+L + LDRE+ + L + DGG PP + +
Sbjct: 172 LSLNPS----FSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTE 227
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
LR+ V D NDN P F R Y L EN P G +V+QV A D D+G N+EI Y+F++ ++
Sbjct: 228 LRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI 287
Query: 326 VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 385
L+ +G IT Q +D E+ T +S++ + R A+ V + ++D NDN+P
Sbjct: 288 ----FSLNSKSGEITTQKKLDFEE--TKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSP 341
Query: 386 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 445
+ + + I E+ T +AL+++ D+D GEN V C + G+VPF++
Sbjct: 342 EVTFHSL--------LEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKII-- 391
Query: 446 SETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
S SK Y L T LD E+ +Y + I A D G PPLSS+ S+ + + DVNDNAPV
Sbjct: 392 ----SSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPV 447
Query: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL---EPEPAAKGLF-TISPET 561
F Q+ V+ PENN PG IA++ ASD D G N ++ YS+ + EP A + ++S ++
Sbjct: 448 FHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQS 507
Query: 562 GEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM---LSGYN 618
G + + + D EQ ++EL + A D+GSP+L ++ V V D NDN P+ + L
Sbjct: 508 GVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDG 567
Query: 619 FSVMENMPALSPVG----MVTVIDGDKGENAQVQLSVEQ--DNGDFVIQNGTGTILSSLS 672
++ + +P + G V +D D G NA + V Q + G F + TG + ++ +
Sbjct: 568 SALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARA 627
Query: 673 FDREQQSTYTFQLKAVDGGVPPRSA 697
+ + DGG PP SA
Sbjct: 628 LGDRDAARQRLLVAVRDGGQPPLSA 652
Score = 239 bits (611), Expect = 9e-63
Identities = 186/626 (29%), Positives = 300/626 (47%), Gaps = 56/626 (8%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
+ V + D ND+ PKF + S+E ++SE++ G I A D+D G N+ +Y P
Sbjct: 119 VNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSF 178
Query: 326 VRRLLRLDRNTGL----ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMN 381
L+ ++ G + ++ +DRE S R + A D G P S ++ + V D N
Sbjct: 179 --SLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDAN 236
Query: 382 DNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ 441
DN P R + V+ + E+V T V V +D+DEG N+ +T +
Sbjct: 237 DNPPVFN-RDVYRVS-------LRENVPPGTTVLQVSATDQDEGINSEIT--------YS 280
Query: 442 LRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
+ + S + K + T LD+E+ K+Y++ + D G L + ++++ + D ND
Sbjct: 281 FYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDEND 338
Query: 502 NAPVFT-QSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE 560
N+P T S+ E+ EN PG +IA I D DSG N E+ L+ E K + + S
Sbjct: 339 NSPEVTFHSLLEMIL-ENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFK-IISSSKN 396
Query: 561 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 620
+ ++ +LDREQ Y + + A DRG P L + +V++++ D NDN P F + Y S
Sbjct: 397 SYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVS 456
Query: 621 VMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDN------GDFVIQNG-TGTILSSLSF 673
V EN P + + V D D G N QV S+ + +V + +G + + +F
Sbjct: 457 VPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAF 516
Query: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS-----NTSHKLLTP 728
D EQ T+ L+A D G P SA V + + V D NDNAP + P+ + ++
Sbjct: 517 DYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPR 576
Query: 729 QTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLH 788
G V++V A D DSG NA L Y + + GLF +G +G + + + R
Sbjct: 577 AAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQ 636
Query: 789 RLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSK 848
RL+V V D G+PP TA +HL ++ L+ +L D P + DP+ E
Sbjct: 637 RLLVAVRDGGQPPLSATATLHLVFADS------LQEVLPDITDRP----VPSDPQAE--- 683
Query: 849 QRGNILFGVVAGVVAVALLIALAVLV 874
+ F +V + +++L LAV++
Sbjct: 684 ----LQFYLVVALALISVLFLLAVIL 705
Score = 48.5 bits (114), Expect = 4e-05
Identities = 63/239 (26%), Positives = 94/239 (39%), Gaps = 45/239 (18%)
Query: 56 HATRVVYKVPEEQPPNTLIGSLAA---DYGFPD-------VGHLYKLEVGAPYLRVDGKT 105
H + VPE PP I + A D G L L + A Y+ + ++
Sbjct: 449 HQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLAL-ASYVSMSAQS 507
Query: 106 GDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDIN 162
G +F + + D E LR FE+++ Q GSP L ++ V D N
Sbjct: 508 GVVFA-QRAFDYEQLRT-------------FELTLQARDQ-GSPALSANVSLRVLVGDRN 552
Query: 163 DNTPNFASPVITL-------AIPENTNIGSLFPIPLASDRDAGPNGVASYE-LQAGPEAQ 214
DN P P + +P G L +A D D+G N SY LQA
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612
Query: 215 ELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDT 273
GL+ E + + +G+ D R L + V+DGG PP +++A L + D+
Sbjct: 613 FSLGLRTGEVRTAR-----ALGDRDAAR---QRLLVAVRDGGQPPLSATATLHLVFADS 663
>gi|11128031 protocadherin gamma subfamily B, 5 isoform 1 precursor
[Homo sapiens]
Length = 923
Score = 338 bits (868), Expect = 1e-92
Identities = 232/685 (33%), Positives = 352/685 (51%), Gaps = 56/685 (8%)
Query: 31 GPGGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHL- 89
G G+ LP + L LL L P+ R Y++PEE P +++G+LA D GF V L
Sbjct: 6 GELGRAERLPVLFLFLLSLFCPALCEQIR--YRIPEEMPKGSVVGNLATDLGF-SVQELP 62
Query: 90 -YKLEVGA--PYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQN 146
KL V + PY V ++G++ + + +DRE E + P C LEFE V
Sbjct: 63 TRKLRVSSEKPYFTVSAESGELLVS-SRLDRE---EICGKKPA--CALEFEA-----VAE 111
Query: 147 GSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
+E++DIND+TP F L I E+ G+ F + +A D D G N + Y+
Sbjct: 112 NPLNFYHVNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYK 171
Query: 207 LQAGPEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSAL 265
L P F L + E Q+ K P+L + LDRE+ + L + DGG PP + +
Sbjct: 172 LSLNPS----FSLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTE 227
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
LR+ V D NDN P F R Y L EN P G +V+QV A D D+G N+EI Y+F++ ++
Sbjct: 228 LRIQVTDANDNPPVFNRDVYRVSLRENVPPGTTVLQVSATDQDEGINSEITYSFYRTGQI 287
Query: 326 VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 385
L+ +G IT Q +D E+ T +S++ + R A+ V + ++D NDN+P
Sbjct: 288 ----FSLNSKSGEITTQKKLDFEE--TKEYSMVVEGRDGGGLVAQCTVEINIQDENDNSP 341
Query: 386 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 445
+ + + I E+ T +AL+++ D+D GEN V C + G+VPF++
Sbjct: 342 EVTFHSL--------LEMILENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFKII-- 391
Query: 446 SETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
S SK Y L T LD E+ +Y + I A D G PPLSS+ S+ + + DVNDNAPV
Sbjct: 392 ----SSSKNSYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPV 447
Query: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL---EPEPAAKGLF-TISPET 561
F Q+ V+ PENN PG IA++ ASD D G N ++ YS+ + EP A + ++S ++
Sbjct: 448 FHQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQS 507
Query: 562 GEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM---LSGYN 618
G + + + D EQ ++EL + A D+GSP+L ++ V V D NDN P+ + L
Sbjct: 508 GVVFAQRAFDYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDG 567
Query: 619 FSVMENMPALSPVG----MVTVIDGDKGENAQVQLSVEQ--DNGDFVIQNGTGTILSSLS 672
++ + +P + G V +D D G NA + V Q + G F + TG + ++ +
Sbjct: 568 SALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARA 627
Query: 673 FDREQQSTYTFQLKAVDGGVPPRSA 697
+ + DGG PP SA
Sbjct: 628 LGDRDAARQRLLVAVRDGGQPPLSA 652
Score = 239 bits (611), Expect = 9e-63
Identities = 186/626 (29%), Positives = 300/626 (47%), Gaps = 56/626 (8%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
+ V + D ND+ PKF + S+E ++SE++ G I A D+D G N+ +Y P
Sbjct: 119 VNVEIEDINDHTPKFTQNSFELQISESAQPGTRFILEVAEDADIGLNSLQKYKLSLNPSF 178
Query: 326 VRRLLRLDRNTGL----ITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMN 381
L+ ++ G + ++ +DRE S R + A D G P S ++ + V D N
Sbjct: 179 --SLIIKEKQDGSKYPELALEKTLDREQQSYHRLVLTALDGGHPPLSGTTELRIQVTDAN 236
Query: 382 DNAPTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQ 441
DN P R + V+ + E+V T V V +D+DEG N+ +T +
Sbjct: 237 DNPPVFN-RDVYRVS-------LRENVPPGTTVLQVSATDQDEGINSEIT--------YS 280
Query: 442 LRQASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVND 501
+ + S + K + T LD+E+ K+Y++ + D G L + ++++ + D ND
Sbjct: 281 FYRTGQIFSLNSKSGEITTQKKLDFEETKEYSMVVEGRDGGG--LVAQCTVEINIQDEND 338
Query: 502 NAPVFT-QSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPE 560
N+P T S+ E+ EN PG +IA I D DSG N E+ L+ E K + + S
Sbjct: 339 NSPEVTFHSLLEMIL-ENAVPGTLIALIKIHDQDSGENGEVNCQLQGEVPFK-IISSSKN 396
Query: 561 TGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFS 620
+ ++ +LDREQ Y + + A DRG P L + +V++++ D NDN P F + Y S
Sbjct: 397 SYKLVTDGTLDREQTPEYNVTITATDRGKPPLSSSISVILHIRDVNDNAPVFHQASYLVS 456
Query: 621 VMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDN------GDFVIQNG-TGTILSSLSF 673
V EN P + + V D D G N QV S+ + +V + +G + + +F
Sbjct: 457 VPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLALASYVSMSAQSGVVFAQRAF 516
Query: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS-----NTSHKLLTP 728
D EQ T+ L+A D G P SA V + + V D NDNAP + P+ + ++
Sbjct: 517 DYEQLRTFELTLQARDQGSPALSANVSLRVLVGDRNDNAPRVLYPALGPDGSALFDMVPR 576
Query: 729 QTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLH 788
G V++V A D DSG NA L Y + + GLF +G +G + + + R
Sbjct: 577 AAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQ 636
Query: 789 RLVVKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSK 848
RL+V V D G+PP TA +HL ++ L+ +L D P + DP+ E
Sbjct: 637 RLLVAVRDGGQPPLSATATLHLVFADS------LQEVLPDITDRP----VPSDPQAE--- 683
Query: 849 QRGNILFGVVAGVVAVALLIALAVLV 874
+ F +V + +++L LAV++
Sbjct: 684 ----LQFYLVVALALISVLFLLAVIL 705
Score = 48.5 bits (114), Expect = 4e-05
Identities = 63/239 (26%), Positives = 94/239 (39%), Gaps = 45/239 (18%)
Query: 56 HATRVVYKVPEEQPPNTLIGSLAA---DYGFPD-------VGHLYKLEVGAPYLRVDGKT 105
H + VPE PP I + A D G L L + A Y+ + ++
Sbjct: 449 HQASYLVSVPENNPPGASIAQVCASDLDLGLNGQVSYSIMASDLEPLAL-ASYVSMSAQS 507
Query: 106 GDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDIN 162
G +F + + D E LR FE+++ Q GSP L ++ V D N
Sbjct: 508 GVVFA-QRAFDYEQLRT-------------FELTLQARDQ-GSPALSANVSLRVLVGDRN 552
Query: 163 DNTPNFASPVITL-------AIPENTNIGSLFPIPLASDRDAGPNGVASYE-LQAGPEAQ 214
DN P P + +P G L +A D D+G N SY LQA
Sbjct: 553 DNAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGL 612
Query: 215 ELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDT 273
GL+ E + + +G+ D R L + V+DGG PP +++A L + D+
Sbjct: 613 FSLGLRTGEVRTAR-----ALGDRDAAR---QRLLVAVRDGGQPPLSATATLHLVFADS 663
>gi|9256604 protocadherin beta 11 precursor [Homo sapiens]
Length = 797
Score = 338 bits (867), Expect = 2e-92
Identities = 237/703 (33%), Positives = 360/703 (51%), Gaps = 51/703 (7%)
Query: 34 GQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFP-----DVGH 88
G R +L L +LL S + + V EE + +G+LA D G G
Sbjct: 5 GTRTQQIRQVLLLFVLLGMSQAGSETWSFSVAEEMQSGSFVGNLAKDLGLKVRELSSRGA 64
Query: 89 LYKLEVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGS 148
L++D TGD+ +ET +DRE L C + +PC+L +V L+QN +
Sbjct: 65 RVVSNDKKQRLQLDINTGDLLLSET-LDREEL--CGSI---EPCVLHLQV----LMQNPT 114
Query: 149 PRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQ 208
+ L+ +++V+DIND++P F+ + L IPEN+ +G++F + A D D G N V SY +
Sbjct: 115 -QFLQIELQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTIS 173
Query: 209 AGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRV 268
P + ++V D K P+L++ LD E + DGGSPPR+ +AL+RV
Sbjct: 174 --PNSHFHIKMRVIPDNR-KYPELVLDKALDYEELPELSFILSALDGGSPPRSGTALVRV 230
Query: 269 TVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRR 328
V+D NDN+P+FE+ YE ++ ENS +G ++ V A D D G N EI YTF A E +R+
Sbjct: 231 VVVDINDNSPEFEQAFYEVKIRENSILGSLILIVSAWDLDSGTNGEICYTFSHASEDIRK 290
Query: 329 LLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIE 388
+++ +G IT++ P+D E + + + A D G ++ V++ V D+NDNAP I
Sbjct: 291 TFEINQKSGEITLRAPLDFETIESYSIIIQATDGG--GLFGKSTVIIHVIDVNDNAPEIT 348
Query: 389 IRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
+ I + I E+ ET V + + D D G+N + C + D+PF L+ + E
Sbjct: 349 VSSI--------TSPIPEN-TPETVVMVFSIQDIDSGDNGRIVCSIPEDLPFVLKSSVE- 398
Query: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQ 508
Y L+T PLD E +Y I I D G P L + ++ V V DVNDNAP FTQ
Sbjct: 399 -----NYYTLETERPLDRESTAEYNITITVTDLGIPRLKTEHNTTVLVSDVNDNAPTFTQ 453
Query: 509 SVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPE-----PAAKGLFTISPETGE 563
+ + ENN P I ++A+D DSG+NA++ YSL P P A L +I+ + G
Sbjct: 454 TSYTLFVRENNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLA-SLVSINTDNGH 512
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSV-- 621
+ SLD E ++++ +V A DRGSP+L A V V VLD NDN P + N S
Sbjct: 513 LFALRSLDYEALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPC 572
Query: 622 MENMPALSPVG----MVTVIDGDKGENA--QVQLSVEQDNGDFVIQNGTGTILSSLSFDR 675
E +P + G V +DGD G+NA QL + G F + G + ++
Sbjct: 573 TELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSE 632
Query: 676 EQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP 718
+ + + D G PPRSA + + ++D + PY+ P
Sbjct: 633 RDAAKHRLVVLVKDNGEPPRSATATLQVLLVD-GFSQPYLPLP 674
Score = 236 bits (601), Expect = 1e-61
Identities = 190/633 (30%), Positives = 275/633 (43%), Gaps = 44/633 (6%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPE- 324
+ + V D ND++P F E+ ENSP+G + A D D G NA YT
Sbjct: 119 IELQVRDINDHSPIFSEKQMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTISPNSHF 178
Query: 325 -VVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
+ R++ +R + + +D E+L L F + A D G+ P+S A V V V D+NDN
Sbjct: 179 HIKMRVIPDNRKYPELVLDKALDYEELPELSFILSALDGGSPPRSGTALVRVVVVDINDN 238
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
+P E + I E+ + + +V D D G N + C +R
Sbjct: 239 SPEFEQAFYEV--------KIRENSILGSLILIVSAWDLDSGTNGEI-CYTFSHASEDIR 289
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
+ E S + + PLD+E ++ Y+I I A D G L +++ + V+DVNDNA
Sbjct: 290 KTFEINQKSGE---ITLRAPLDFETIESYSIIIQATDGGG--LFGKSTVIIHVIDVNDNA 344
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
P T S PEN P V+ + D DSG N +V S+ PE L +
Sbjct: 345 PEITVSSITSPIPENT-PETVVMVFSIQDIDSGDNGRIVCSI-PEDLPFVLKSSVENYYT 402
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
++ + LDRE Y + + D G P L+ V V D NDN P F + Y V E
Sbjct: 403 LETERPLDRESTAEYNITITVTDLGIPRLKTEHNTTVLVSDVNDNAPTFTQTSYTLFVRE 462
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFV-------IQNGTGTILSSLSFDRE 676
N +G V+ D D G NAQV S+ + I G + + S D E
Sbjct: 463 NNSPALHIGSVSATDRDSGTNAQVNYSLLPPQDLHLPLASLVSINTDNGHLFALRSLDYE 522
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP----SNTSHKLLTPQTRL 732
+ F++ A D G P S+ V + VLD NDN+P++ P S +L+
Sbjct: 523 ALQAFDFRVGATDRGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEP 582
Query: 733 GETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVV 792
G V++V A D DSG NA L Y + GLF + +H+G + + + R HRLVV
Sbjct: 583 GYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKHRLVV 642
Query: 793 KVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGN 852
V D G+PPR TA L+ LL P P ++
Sbjct: 643 LVKDNGEPPRSATA--------------TLQVLLVDGFSQPYLPLPEAAPAQAQADSLTV 688
Query: 853 ILFGVVAGVVAVALL-IALAVLVRYCRQREAKS 884
L +A V ++ L + L V VR CR+ A S
Sbjct: 689 YLVVALASVSSLFLFSVLLFVAVRLCRRSRAAS 721
>gi|11128035 protocadherin gamma subfamily B, 2 isoform 1 precursor
[Homo sapiens]
Length = 931
Score = 334 bits (856), Expect = 4e-91
Identities = 235/675 (34%), Positives = 339/675 (50%), Gaps = 53/675 (7%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHL--YKLEVGAP-- 97
+LL LL L P ++ Y +PEE N+++G+LA D G V L KL V A
Sbjct: 16 VLLPFLLSLFPG-ALPVQIRYSIPEELAKNSVVGNLAKDLGL-SVRDLPARKLRVSAEKE 73
Query: 98 YLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIE 157
Y V+ ++GD+ ++ IDRE + C Q C+L+F D V + +
Sbjct: 74 YFTVNPESGDLLVSDR-IDREQI--CGKQ---PLCVLDF-----DTVAENPLNIFYIAVI 122
Query: 158 VQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELF 217
VQDINDNTP F I L I E+T G+ FP+ A D D GPN + Y L E F
Sbjct: 123 VQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDN----EYF 178
Query: 218 GLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDN 276
L + + K P+LI+ +LDRE + L + DGG PP++ + +R+ V D NDN
Sbjct: 179 DLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDN 238
Query: 277 APKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNT 336
P F + Y L E+ P G V+QV A D D+G NAEI Y+FH E V+ L+ T
Sbjct: 239 PPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKT 298
Query: 337 GLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
G IT + +D E S+ S+ AKD G +A + V + D ND AP + + +
Sbjct: 299 GEITTKDDLDFEIASSYTLSIEAKDPG--DLAAHCSIQVEILDDNDCAPEVIVTSVS--- 353
Query: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
+ ED T +AL++ DRD GEN V C V G+ F L+ S SK Y
Sbjct: 354 -----TPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILK------SSSKNYY 402
Query: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
L T LD E++ +Y + I A D G PPLSS+ + + + DVNDNAPVF Q+ V
Sbjct: 403 KLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVA 462
Query: 517 ENNKPGEVIAEITASDADSGSNAELVYS-----LEPEPAAKGLFTISPETGEIQVKTSLD 571
ENN PG IA+I+ASD D G + ++ YS L+P ++S ++G + + + D
Sbjct: 463 ENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREIL-SYVSVSAQSGVVFAQRAFD 521
Query: 572 REQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM---LSGYNFSVMENMPAL 628
EQ ++EL + A D+GSP+L ++ V V D NDN P+ + L ++ + +P
Sbjct: 522 HEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRA 581
Query: 629 SPVG----MVTVIDGDKGENAQVQLSVEQ--DNGDFVIQNGTGTILSSLSFDREQQSTYT 682
+ G V +D D G NA + V Q + G F + TG + ++ + +
Sbjct: 582 AEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQR 641
Query: 683 FQLKAVDGGVPPRSA 697
+ DGG PP SA
Sbjct: 642 LLVAVRDGGQPPLSA 656
Score = 221 bits (563), Expect = 3e-57
Identities = 189/665 (28%), Positives = 298/665 (44%), Gaps = 54/665 (8%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAP-- 323
+ V V D NDN P F++ ++ E++ G + A DSD G N+ Y +
Sbjct: 119 IAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYF 178
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
++ + R + ++ +DRE+ S + + A D G P+S Q+ + V D NDN
Sbjct: 179 DLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDN 238
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P + + VT + EDV V V +DRDEG NA +T +V Q++
Sbjct: 239 PPVFS-QDVYRVT-------LREDVPPGFFVLQVTATDRDEGINAEITYSFH-NVDEQVK 289
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++K + T LD+E YT+ I A D G+ L++ S++V+++D ND A
Sbjct: 290 HFFNL---NEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCA 344
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
P + PE++ PG VIA I D DSG N E VY A L + S +
Sbjct: 345 PEVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENGE-VYCQVLGNAKFILKSSSKNYYK 403
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ +LDRE+ Y L + A D G P L + V +++ D NDN P F + Y V E
Sbjct: 404 LVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAE 463
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDN-------GDFVIQNGTGTILSSLSFDRE 676
N P + + ++ D D G + QV S+ + + +G + + +FD E
Sbjct: 464 NNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHE 523
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS-----NTSHKLLTPQTR 731
Q + L+A D G P SA V + + V D NDNAP + P+ + ++
Sbjct: 524 QLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAE 583
Query: 732 LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
G V++V A D DSG NA L Y + + GLF +G +G + + + R RL+
Sbjct: 584 PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLL 643
Query: 792 VKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRG 851
V V D G+PP TA +HL ++L + +L L E S +
Sbjct: 644 VAVRDGGQPPLSATATLHLIFADSL--QEVLPDL---------------SDRREPSDPQA 686
Query: 852 NILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKG--- 908
+ F +V + +++L LAV++ + S + + D + P S K G
Sbjct: 687 KLQFYLVVALALISVLFFLAVILAISLRLRLSS-----RSDAWDCFQPGLSSKPGPGVLP 741
Query: 909 NKSKG 913
N S+G
Sbjct: 742 NYSEG 746
Score = 49.7 bits (117), Expect = 2e-05
Identities = 61/238 (25%), Positives = 95/238 (39%), Gaps = 47/238 (19%)
Query: 58 TRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGA-----------PYLRVDGKTG 106
T + V E PP I ++A PD+G ++ Y+ V ++G
Sbjct: 455 TSYMVHVAENNPPGASIAQISASD--PDLGPSGQVSYSIVASDLKPREILSYVSVSAQSG 512
Query: 107 DIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDIND 163
+F + + D E LR FE+++ Q GSP L ++ V D+ND
Sbjct: 513 VVFA-QRAFDHEQLRA-------------FELTLQARDQ-GSPALSANVSLRVLVGDLND 557
Query: 164 NTPNFASPVITL-------AIPENTNIGSLFPIPLASDRDAGPNGVASYE-LQAGPEAQE 215
N P P + +P G L +A D D+G N SY LQA
Sbjct: 558 NAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLF 617
Query: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDT 273
GL+ E + + +G+ D R L + V+DGG PP +++A L + D+
Sbjct: 618 SLGLRTGEVRTAR-----ALGDRDAAR---QRLLVAVRDGGQPPLSATATLHLIFADS 667
>gi|14270493 protocadherin gamma subfamily B, 2 isoform 2 precursor
[Homo sapiens]
Length = 811
Score = 334 bits (856), Expect = 4e-91
Identities = 235/675 (34%), Positives = 339/675 (50%), Gaps = 53/675 (7%)
Query: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHL--YKLEVGAP-- 97
+LL LL L P ++ Y +PEE N+++G+LA D G V L KL V A
Sbjct: 16 VLLPFLLSLFPG-ALPVQIRYSIPEELAKNSVVGNLAKDLGL-SVRDLPARKLRVSAEKE 73
Query: 98 YLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEGQIE 157
Y V+ ++GD+ ++ IDRE + C Q C+L+F D V + +
Sbjct: 74 YFTVNPESGDLLVSDR-IDREQI--CGKQ---PLCVLDF-----DTVAENPLNIFYIAVI 122
Query: 158 VQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELF 217
VQDINDNTP F I L I E+T G+ FP+ A D D GPN + Y L E F
Sbjct: 123 VQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDN----EYF 178
Query: 218 GLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDTNDN 276
L + + K P+LI+ +LDRE + L + DGG PP++ + +R+ V D NDN
Sbjct: 179 DLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDN 238
Query: 277 APKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVVRRLLRLDRNT 336
P F + Y L E+ P G V+QV A D D+G NAEI Y+FH E V+ L+ T
Sbjct: 239 PPVFSQDVYRVTLREDVPPGFFVLQVTATDRDEGINAEITYSFHNVDEQVKHFFNLNEKT 298
Query: 337 GLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVT 396
G IT + +D E S+ S+ AKD G +A + V + D ND AP + + +
Sbjct: 299 GEITTKDDLDFEIASSYTLSIEAKDPG--DLAAHCSIQVEILDDNDCAPEVIVTSVS--- 353
Query: 397 HQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASETGSDSKKKY 456
+ ED T +AL++ DRD GEN V C V G+ F L+ S SK Y
Sbjct: 354 -----TPLPEDSPPGTVIALIKTRDRDSGENGEVYCQVLGNAKFILK------SSSKNYY 402
Query: 457 FLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFP 516
L T LD E++ +Y + I A D G PPLSS+ + + + DVNDNAPVF Q+ V
Sbjct: 403 KLVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVA 462
Query: 517 ENNKPGEVIAEITASDADSGSNAELVYS-----LEPEPAAKGLFTISPETGEIQVKTSLD 571
ENN PG IA+I+ASD D G + ++ YS L+P ++S ++G + + + D
Sbjct: 463 ENNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREIL-SYVSVSAQSGVVFAQRAFD 521
Query: 572 REQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFM---LSGYNFSVMENMPAL 628
EQ ++EL + A D+GSP+L ++ V V D NDN P+ + L ++ + +P
Sbjct: 522 HEQLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRA 581
Query: 629 SPVG----MVTVIDGDKGENAQVQLSVEQ--DNGDFVIQNGTGTILSSLSFDREQQSTYT 682
+ G V +D D G NA + V Q + G F + TG + ++ + +
Sbjct: 582 AEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQR 641
Query: 683 FQLKAVDGGVPPRSA 697
+ DGG PP SA
Sbjct: 642 LLVAVRDGGQPPLSA 656
Score = 221 bits (563), Expect = 3e-57
Identities = 189/665 (28%), Positives = 298/665 (44%), Gaps = 54/665 (8%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAP-- 323
+ V V D NDN P F++ ++ E++ G + A DSD G N+ Y +
Sbjct: 119 IAVIVQDINDNTPLFKQTKINLKIGESTKPGTTFPLDPALDSDVGPNSLQRYHLNDNEYF 178
Query: 324 EVVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
++ + R + ++ +DRE+ S + + A D G P+S Q+ + V D NDN
Sbjct: 179 DLAEKQTPDGRKYPELILKHSLDREEHSLHQLVLTAVDGGDPPQSGTTQIRIKVTDANDN 238
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
P + + VT + EDV V V +DRDEG NA +T +V Q++
Sbjct: 239 PPVFS-QDVYRVT-------LREDVPPGFFVLQVTATDRDEGINAEITYSFH-NVDEQVK 289
Query: 444 QASETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNA 503
++K + T LD+E YT+ I A D G+ L++ S++V+++D ND A
Sbjct: 290 HFFNL---NEKTGEITTKDDLDFEIASSYTLSIEAKDPGD--LAAHCSIQVEILDDNDCA 344
Query: 504 PVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE 563
P + PE++ PG VIA I D DSG N E VY A L + S +
Sbjct: 345 PEVIVTSVSTPLPEDSPPGTVIALIKTRDRDSGENGE-VYCQVLGNAKFILKSSSKNYYK 403
Query: 564 IQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVME 623
+ +LDRE+ Y L + A D G P L + V +++ D NDN P F + Y V E
Sbjct: 404 LVTDGALDREEIPEYNLTITATDGGKPPLSSSIIVTLHISDVNDNAPVFQQTSYMVHVAE 463
Query: 624 NMPALSPVGMVTVIDGDKGENAQVQLSVEQDN-------GDFVIQNGTGTILSSLSFDRE 676
N P + + ++ D D G + QV S+ + + +G + + +FD E
Sbjct: 464 NNPPGASIAQISASDPDLGPSGQVSYSIVASDLKPREILSYVSVSAQSGVVFAQRAFDHE 523
Query: 677 QQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPS-----NTSHKLLTPQTR 731
Q + L+A D G P SA V + + V D NDNAP + P+ + ++
Sbjct: 524 QLRAFELTLQARDQGSPALSANVSLRVLVGDLNDNAPRVLYPALGPDGSALFDMVPRAAE 583
Query: 732 LGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLV 791
G V++V A D DSG NA L Y + + GLF +G +G + + + R RL+
Sbjct: 584 PGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLFSLGLRTGEVRTARALGDRDAARQRLL 643
Query: 792 VKVSDRGKPPRYGTALVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRG 851
V V D G+PP TA +HL ++L + +L L E S +
Sbjct: 644 VAVRDGGQPPLSATATLHLIFADSL--QEVLPDL---------------SDRREPSDPQA 686
Query: 852 NILFGVVAGVVAVALLIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKG--- 908
+ F +V + +++L LAV++ + S + + D + P S K G
Sbjct: 687 KLQFYLVVALALISVLFFLAVILAISLRLRLSS-----RSDAWDCFQPGLSSKPGPGVLP 741
Query: 909 NKSKG 913
N S+G
Sbjct: 742 NYSEG 746
Score = 49.7 bits (117), Expect = 2e-05
Identities = 61/238 (25%), Positives = 95/238 (39%), Gaps = 47/238 (19%)
Query: 58 TRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKLEVGA-----------PYLRVDGKTG 106
T + V E PP I ++A PD+G ++ Y+ V ++G
Sbjct: 455 TSYMVHVAENNPPGASIAQISASD--PDLGPSGQVSYSIVASDLKPREILSYVSVSAQSG 512
Query: 107 DIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPRLLEG---QIEVQDIND 163
+F + + D E LR FE+++ Q GSP L ++ V D+ND
Sbjct: 513 VVFA-QRAFDHEQLRA-------------FELTLQARDQ-GSPALSANVSLRVLVGDLND 557
Query: 164 NTPNFASPVITL-------AIPENTNIGSLFPIPLASDRDAGPNGVASYE-LQAGPEAQE 215
N P P + +P G L +A D D+G N SY LQA
Sbjct: 558 NAPRVLYPALGPDGSALFDMVPRAAEPGYLVTKVVAVDADSGHNAWLSYHVLQASEPGLF 617
Query: 216 LFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVTVLDT 273
GL+ E + + +G+ D R L + V+DGG PP +++A L + D+
Sbjct: 618 SLGLRTGEVRTAR-----ALGDRDAAR---QRLLVAVRDGGQPPLSATATLHLIFADS 667
>gi|9256606 protocadherin beta 12 precursor [Homo sapiens]
Length = 795
Score = 333 bits (853), Expect = 8e-91
Identities = 236/704 (33%), Positives = 355/704 (50%), Gaps = 51/704 (7%)
Query: 33 GGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYKL 92
GG L +L +LL S + + V EE + +G+LA G +V L
Sbjct: 4 GGAGTLQIRQVLLFFVLLGMSQAGSETGNFLVMEELQSGSFVGNLAKTLGL-EVSELSSR 62
Query: 93 EV------GAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQN 146
L++D TGD+ E +DRE L C + +PC+L F+V + + Q
Sbjct: 63 GARVVSNDNKECLQLDTNTGDLLLREM-LDREEL--CGSN---EPCVLYFQVLMKNPTQ- 115
Query: 147 GSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYE 206
L+ +++V+DIND++P F + L IPEN+ +G++F + A D D G N V SY
Sbjct: 116 ----FLQIELQVRDINDHSPVFLEKEMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYT 171
Query: 207 LQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALL 266
+ P + ++V D K P+L++ LD E + DGGSPPR+ +AL+
Sbjct: 172 IN--PNSHFHVKIRVNPDNR-KYPELVLDKALDYEERPELSFILTALDGGSPPRSGTALV 228
Query: 267 RVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEVV 326
RV V+D NDN+P+FE+ YE ++ ENS +G V+ V A D D G N+E+ YTF A E +
Sbjct: 229 RVVVVDINDNSPEFEQAFYEVKILENSILGSLVVTVSAWDLDSGTNSELSYTFSHASEDI 288
Query: 327 RRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPT 386
R+ +++ +G IT+ P+D E + + + A D G ++ V + V D+NDNAP
Sbjct: 289 RKTFEINQKSGDITLTAPLDFEAIESYSIIIQATDGG--GLFGKSTVRIQVMDVNDNAPE 346
Query: 387 IEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQAS 446
I + I + I E+ ET V + ++ DRD G+N + C + D+PF L+
Sbjct: 347 ITVSSI--------TSPIPEN-TPETVVMVFRIRDRDSGDNGKMVCSIPEDIPFVLK--- 394
Query: 447 ETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVF 506
S Y L+T PLD E +Y I I D G P L + +++ V V DVNDNAP F
Sbjct: 395 ---SSVNNYYTLETERPLDRESRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAF 451
Query: 507 TQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL----EPEPAAKGLFTISPETG 562
TQ+ + ENN P I I+A+D DSG+NA++ YSL +P L +I+ + G
Sbjct: 452 TQTSYALFVRENNSPALHIGSISATDRDSGTNAQVNYSLLPSQDPHLPLASLVSINADNG 511
Query: 563 EIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSV- 621
+ SLD E + ++ +V A D GSP+L A V V VLD NDN P + N S
Sbjct: 512 HLFALRSLDYEALQGFQFRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAP 571
Query: 622 -MENMP-ALSP---VGMVTVIDGDKGENA--QVQLSVEQDNGDFVIQNGTGTILSSLSFD 674
E +P A P V V +DGD G+NA QL + G F + G + ++
Sbjct: 572 CTELVPWAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLS 631
Query: 675 REQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP 718
+ + + D G PPRSA + + ++D + PY+ P
Sbjct: 632 ERDAAKHRLVVLVKDNGEPPRSATATLHVLLVD-GFSQPYLPLP 674
Score = 237 bits (605), Expect = 5e-62
Identities = 178/562 (31%), Positives = 260/562 (46%), Gaps = 37/562 (6%)
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPE- 324
+ + V D ND++P F E+ ENSP+G + A D D G NA YT +
Sbjct: 119 IELQVRDINDHSPVFLEKEMLLEIPENSPVGAVFLLESAKDLDVGINAVKSYTINPNSHF 178
Query: 325 -VVRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDN 383
V R+ +R + + +D E+ L F + A D G+ P+S A V V V D+NDN
Sbjct: 179 HVKIRVNPDNRKYPELVLDKALDYEERPELSFILTALDGGSPPRSGTALVRVVVVDINDN 238
Query: 384 APTIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLR 443
+P E + I E+ + V V D D G N+ ++ +
Sbjct: 239 SPEFEQAFYEV--------KILENSILGSLVVTVSAWDLDSGTNS--------ELSYTFS 282
Query: 444 QASE----TGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDV 499
ASE T ++K + T PLD+E ++ Y+I I A D G L +++++QV+DV
Sbjct: 283 HASEDIRKTFEINQKSGDITLTAPLDFEAIESYSIIIQATDGGG--LFGKSTVRIQVMDV 340
Query: 500 NDNAPVFTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISP 559
NDNAP T S PEN P V+ D DSG N ++V S+ PE L +
Sbjct: 341 NDNAPEITVSSITSPIPENT-PETVVMVFRIRDRDSGDNGKMVCSI-PEDIPFVLKSSVN 398
Query: 560 ETGEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNF 619
++ + LDRE R Y + + D G+P L+ + V V D NDN P F + Y
Sbjct: 399 NYYTLETERPLDRESRAEYNITITVTDLGTPRLKTEHNITVLVSDVNDNAPAFTQTSYAL 458
Query: 620 SVMENMPALSPVGMVTVIDGDKGENAQVQLSVEQDNGDFV-------IQNGTGTILSSLS 672
V EN +G ++ D D G NAQV S+ + I G + + S
Sbjct: 459 FVRENNSPALHIGSISATDRDSGTNAQVNYSLLPSQDPHLPLASLVSINADNGHLFALRS 518
Query: 673 FDREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP----SNTSHKLLTP 728
D E + F++ A D G P S+ V + VLD NDN+P++ P S +L+
Sbjct: 519 LDYEALQGFQFRVGATDHGSPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPW 578
Query: 729 QTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLH 788
G V++V A D DSG NA L Y + GLF + +H+G + + + R H
Sbjct: 579 AAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDAAKH 638
Query: 789 RLVVKVSDRGKPPRYGTALVHL 810
RLVV V D G+PPR TA +H+
Sbjct: 639 RLVVLVKDNGEPPRSATATLHV 660
Score = 40.4 bits (93), Expect = 0.011
Identities = 50/211 (23%), Positives = 85/211 (40%), Gaps = 26/211 (12%)
Query: 618 NFSVMENMPALSPVGMVTVIDGDKGENAQVQLS--VEQDNGDFV-IQNGTGTILSSLSFD 674
NF VME + + S VG + G + + + V DN + + + TG +L D
Sbjct: 32 NFLVMEELQSGSFVGNLAKTLGLEVSELSSRGARVVSNDNKECLQLDTNTGDLLLREMLD 91
Query: 675 REQ------QSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAPSNTSHKLLTP 728
RE+ FQ+ + + ++ + + V D ND++P +
Sbjct: 92 REELCGSNEPCVLYFQVLMKNP-----TQFLQIELQVRDINDHSPVFLEKEMLLE--IPE 144
Query: 729 QTRLGETVSQVAAEDFDSGVNAELIYSIAGGNPYGLFQIGSHSGA-------ITLEKEIE 781
+ +G +A+D D G+NA Y+I NP F + + L+K ++
Sbjct: 145 NSPVGAVFLLESAKDLDVGINAVKSYTI---NPNSHFHVKIRVNPDNRKYPELVLDKALD 201
Query: 782 RRHHGLHRLVVKVSDRGKPPRYGTALVHLYV 812
++ D G PPR GTALV + V
Sbjct: 202 YEERPELSFILTALDGGSPPRSGTALVRVVV 232
>gi|9256610 protocadherin beta 15 precursor [Homo sapiens]
Length = 787
Score = 333 bits (853), Expect = 8e-91
Identities = 237/705 (33%), Positives = 352/705 (49%), Gaps = 51/705 (7%)
Query: 32 PGGQRLLLPSMLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGHLYK 91
P G+R +L LLLLL + Y V EE + + +LA D G VG L +
Sbjct: 3 PAGERFPEQRQVLILLLLLEVTLAGWEPRRYSVMEETERGSFVANLANDLGL-GVGELAE 61
Query: 92 L------EVGAPYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQ 145
E L++D +TG + E +DRE L C P +PCI+ F+V + ++
Sbjct: 62 RGARVVSEDNEQGLQLDLQTGQLILNE-KLDREKL--CG---PTEPCIMHFQVLLKKPLE 115
Query: 146 NGSPRLLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASY 205
+ ++ V DIND++P F +TL IPE +++G++FP+ A D D G N V +Y
Sbjct: 116 -----VFRAELLVTDINDHSPEFPEREMTLKIPETSSLGTVFPLKKARDLDVGSNNVQNY 170
Query: 206 ELQAGPEAQELFGLQVAEDQEEKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSAL 265
+ P + + D K P+L++ LDRE LT+ DGGSPPR+ +
Sbjct: 171 NIS--PNSHFHVSTRTRGDGR-KYPELVLDTELDREEQAELRLTLTAVDGGSPPRSGTVQ 227
Query: 266 LRVTVLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPEV 325
+ + VLD NDNAP+F + YE ++ ENSP+G V++V A D D G N EI Y+ + + +
Sbjct: 228 ILILVLDANDNAPEFVQALYEVQVPENSPVGSLVVKVSARDLDTGTNGEISYSLYYSSQE 287
Query: 326 VRRLLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAP 385
+ + L +G I + +D E +S+ + A D G S + V V V D+NDN P
Sbjct: 288 IDKPFELSSLSGEIRLIKKLDFETMSSYDLDIEASDGG--GLSGKCSVSVKVLDVNDNFP 345
Query: 386 TIEIRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQA 445
+ I + + I E+ + ET VAL ++ DRD GEN + C + DVPF+L+ +
Sbjct: 346 ELSISSL--------TSPIPEN-SPETEVALFRIRDRDSGENGKMICSIQDDVPFKLKPS 396
Query: 446 SETGSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPV 505
E Y L T LD E +Y I I D G P L + S+ V V DVNDNAP
Sbjct: 397 VE------NFYRLVTEGALDRETRAEYNITITITDLGTPRLKTEQSITVLVSDVNDNAPA 450
Query: 506 FTQSVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSL----EPEPAAKGLFTISPET 561
FTQ+ + ENN P I ++A+D DSG+NA++ YSL +P L +I+ +
Sbjct: 451 FTQTSYTLFVRENNSPALHIGSVSATDRDSGTNAQVTYSLLPPRDPHLPLTSLVSINTDN 510
Query: 562 GEIQVKTSLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSV 621
G + SLD E +++E +V A DRG P+L A V V VLD NDN P + N S
Sbjct: 511 GHLFALQSLDYEALQAFEFRVGATDRGFPALSSEALVRVLVLDANDNSPFVLYPLQNGSA 570
Query: 622 --MENMPALSPVG----MVTVIDGDKGENA--QVQLSVEQDNGDFVIQNGTGTILSSLSF 673
E +P + G V +DGD G+NA QL + G F + G + ++
Sbjct: 571 PCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLL 630
Query: 674 DREQQSTYTFQLKAVDGGVPPRSAYVGVTINVLDENDNAPYITAP 718
+ + + D G PPRSA + + ++D + PY+ P
Sbjct: 631 SERDVAKHRLVVLVKDNGEPPRSATATLQVLLVD-GFSQPYLPLP 674
Score = 224 bits (571), Expect = 4e-58
Identities = 215/739 (29%), Positives = 317/739 (42%), Gaps = 81/739 (10%)
Query: 176 AIPENTNIGSLFPIPLASDRDAGPNGVASYELQAGPEAQELFGLQVAEDQEEKQPQLIVM 235
++ E T GS F LA+D G +A + E E GLQ+ + + QLI+
Sbjct: 34 SVMEETERGS-FVANLANDLGLGVGELAERGARVVSEDNEQ-GLQL----DLQTGQLILN 87
Query: 236 GNLDRERWDS--------YDLTIKVQDGGSPPRASSALLRVTVLDTNDNAPKFERPSYEA 287
LDRE+ + + +K P A L VT D ND++P+F
Sbjct: 88 EKLDREKLCGPTEPCIMHFQVLLK-----KPLEVFRAELLVT--DINDHSPEFPEREMTL 140
Query: 288 ELSENSPIGHSVIQVKANDSDQGANAEIEYTFHQAPE--VVRRLLRLDRNTGLITVQGPV 345
++ E S +G KA D D G+N Y V R R + + +
Sbjct: 141 KIPETSSLGTVFPLKKARDLDVGSNNVQNYNISPNSHFHVSTRTRGDGRKYPELVLDTEL 200
Query: 346 DREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANIS 405
DRE+ + LR ++ A D G+ P+S Q+++ V D NDNAP ++ + V +
Sbjct: 201 DREEQAELRLTLTAVDGGSPPRSGTVQILILVLDANDNAPEF-VQALYEV-------QVP 252
Query: 406 EDVAEETAVALVQVSDRDEGENAAVTCVVAG-----DVPFQLRQASETGSDSKKKYFLQT 460
E+ + V V D D G N ++ + D PF+L S KK
Sbjct: 253 ENSPVGSLVVKVSARDLDTGTNGEISYSLYYSSQEIDKPFELSSLSGEIRLIKK------ 306
Query: 461 TTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQSVTEVAFPENNK 520
LD+E + Y ++I A D G LS S+ V+V+DVNDN P + S PEN+
Sbjct: 307 ---LDFETMSSYDLDIEASDGGG--LSGKCSVSVKVLDVNDNFPELSISSLTSPIPENSP 361
Query: 521 PGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGE---IQVKTSLDREQRES 577
EV A D DSG N +++ S++ + F + P + + +LDRE R
Sbjct: 362 ETEV-ALFRIRDRDSGENGKMICSIQDDVP----FKLKPSVENFYRLVTEGALDRETRAE 416
Query: 578 YELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPALSPVGMVTVI 637
Y + + D G+P L+ ++ V V D NDN P F + Y V EN +G V+
Sbjct: 417 YNITITITDLGTPRLKTEQSITVLVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSAT 476
Query: 638 DGDKGENAQVQLSVEQDNGDFV-------IQNGTGTILSSLSFDREQQSTYTFQLKAVDG 690
D D G NAQV S+ + I G + + S D E + F++ A D
Sbjct: 477 DRDSGTNAQVTYSLLPPRDPHLPLTSLVSINTDNGHLFALQSLDYEALQAFEFRVGATDR 536
Query: 691 GVPPRSAYVGVTINVLDENDNAPYITAP----SNTSHKLLTPQTRLGETVSQVAAEDFDS 746
G P S+ V + VLD NDN+P++ P S +L+ G V++V A D DS
Sbjct: 537 GFPALSSEALVRVLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDS 596
Query: 747 GVNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGTA 806
G NA L Y + GLF + +H+G + + + R HRLVV V D G+PPR TA
Sbjct: 597 GQNAWLSYQLLKATEPGLFGVWAHNGEVRTARLLSERDVAKHRLVVLVKDNGEPPRSATA 656
Query: 807 LVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVAL 866
L+ LL P P ++ L +A V ++ L
Sbjct: 657 --------------TLQVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFL 702
Query: 867 L-IALAVLVRYCRQREAKS 884
+ L V VR CR+ A S
Sbjct: 703 FSVFLFVAVRLCRRSRAAS 721
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.131 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,115,358
Number of Sequences: 37866
Number of extensions: 2786148
Number of successful extensions: 16743
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 199
Number of HSP's successfully gapped in prelim test: 129
Number of HSP's that attempted gapping in prelim test: 7438
Number of HSP's gapped (non-prelim): 1263
length of query: 1237
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1123
effective length of database: 13,930,794
effective search space: 15644281662
effective search space used: 15644281662
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.