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Search of human proteins with 27734897
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27734897 hypothetical protein LOC203111 [Homo sapiens]
(374 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27734897 hypothetical protein LOC203111 [Homo sapiens] 738 0.0
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 63 4e-10
gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo ... 55 1e-07
gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo ... 55 1e-07
gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo sa... 49 6e-06
gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo sa... 49 6e-06
gi|56606114 trichohyalin-like 1 [Homo sapiens] 48 1e-05
gi|27894378 chloride intracellular channel 6 [Homo sapiens] 45 1e-04
gi|118421089 chromodomain helicase DNA binding protein 2 isoform... 45 1e-04
gi|110611184 chromodomain helicase DNA binding protein 2 isoform... 45 1e-04
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 43 4e-04
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 43 4e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 43 5e-04
gi|222537747 hypothetical protein LOC342979 [Homo sapiens] 42 7e-04
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 42 7e-04
gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo sap... 42 7e-04
gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo sap... 42 7e-04
gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo sapi... 42 7e-04
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 42 9e-04
gi|112421108 capicua homolog [Homo sapiens] 42 9e-04
gi|23503317 coiled-coil domain containing 96 [Homo sapiens] 42 9e-04
gi|238624188 diffuse panbronchiolitis critical region 1 protein ... 42 0.001
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 41 0.002
gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 41 0.002
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 41 0.002
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 41 0.002
gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 41 0.002
gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 41 0.002
gi|118498345 AT-binding transcription factor 1 [Homo sapiens] 41 0.002
gi|7657138 golgi integral membrane protein 4 [Homo sapiens] 41 0.002
>gi|27734897 hypothetical protein LOC203111 [Homo sapiens]
Length = 374
Score = 738 bits (1906), Expect = 0.0
Identities = 374/374 (100%), Positives = 374/374 (100%)
Query: 1 MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRP 60
MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRP
Sbjct: 1 MGCSSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRP 60
Query: 61 PLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGG 120
PLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGG
Sbjct: 61 PLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGG 120
Query: 121 KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQ 180
KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQ
Sbjct: 121 KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQ 180
Query: 181 TAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETA 240
TAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETA
Sbjct: 181 TAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETA 240
Query: 241 EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQ 300
EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQ
Sbjct: 241 EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQ 300
Query: 301 PEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAETK 360
PEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAETK
Sbjct: 301 PEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAETK 360
Query: 361 EEETGEVVDLSAAT 374
EEETGEVVDLSAAT
Sbjct: 361 EEETGEVVDLSAAT 374
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 63.2 bits (152), Expect = 4e-10
Identities = 75/315 (23%), Positives = 131/315 (41%), Gaps = 51/315 (16%)
Query: 57 ESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPP 116
E+ +Q+ + A+P ++GV+ A+ + G +A + G T+KT+ E G
Sbjct: 2004 EAEGEMQEAEEEAQPESDGVE-------AQPKSEGEEAQEVEGETQKTEGDAQPESDGVE 2056
Query: 117 QPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVT 176
P +E+A AEG+ ++A ES +A+ + + + ++A + + E
Sbjct: 2057 APEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI 2116
Query: 177 ENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQF 236
E P+T E +P +E + + GE QP+ E + ++ E S+
Sbjct: 2117 EAPETEGEAQP--ESEGIEAPEAEGEAQPES-----------EGVEAQDAEGEAQPESEG 2163
Query: 237 VETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNM 296
+E E ++ E QP+ LE + E S+ +E PE G
Sbjct: 2164 IEAQEAEE-------EAQPE-LEGVEAPEAEGEAQPESEGIE----------APEAEG-- 2203
Query: 297 EQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQ-RIEGET-GEKVET------DM 348
+ QPE + +E P EA E + + E Q EGET GEK + D
Sbjct: 2204 -EAQPE--LEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQGEKKGSPQVSLGDG 2260
Query: 349 ENEKVSEGAETKEEE 363
++E+ SE + E+
Sbjct: 2261 QSEEASESSSPVPED 2275
Score = 60.8 bits (146), Expect = 2e-09
Identities = 86/335 (25%), Positives = 137/335 (40%), Gaps = 57/335 (17%)
Query: 52 GNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLE 111
G + ++ ++ K T+ G + + + + ++ + Q E GE
Sbjct: 1761 GEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGGQGSGHEDNLQGEAAA 1820
Query: 112 --ESGPPQPGGKE--DAPAAEGKKKDAGAGTEAESLKGNA-----EAQP-----LGPEAK 157
+ P Q G E +AP AEG+ + G EA +G+A EAQP PEA+
Sbjct: 1821 GGDQDPGQSDGAEGIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAE 1880
Query: 158 G--QPLQAAVEKDSLR-----AVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVG 210
G QP VE E E P+ E +P TE+V L+ GE +P+
Sbjct: 1881 GEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQP--ETESVEALETEGEDEPESEGA 1938
Query: 211 KDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQL--LERIPKENVTP 268
+ ++A ++ PE S+ +E+ E ++ E QP+ +E + E T
Sbjct: 1939 EAQEAEEAAQEAEGQTQPE----SEVIESQEAEE-------EAQPESEDVEALEVEVETQ 1987
Query: 269 EVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIH 328
E +Q + V + PE G M++ + E + + VEA E
Sbjct: 1988 EAEGEAQPESEDV------EAPEAEGEMQEAEEEA-----QPESDGVEAQPKSE------ 2030
Query: 329 TNEEDQRIEGETGEKVETDMENEKVSEGAETKEEE 363
EE Q +EGET +K E D + E S+G E E E
Sbjct: 2031 -GEEAQEVEGET-QKTEGDAQPE--SDGVEAPEAE 2061
Score = 59.3 bits (142), Expect = 5e-09
Identities = 90/367 (24%), Positives = 148/367 (40%), Gaps = 56/367 (15%)
Query: 40 KPHALGRESTVDGNVQRESRPPLQKLKV-----SAEPTANGVKPLQEQPLAKDVA----P 90
+P + G E+ ++E++P + ++ EP + G + + + A++ P
Sbjct: 1900 QPESEGAEAP---EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQP 1956
Query: 91 GRDATDQSGSTEKTQPG-----------EGLEESGPPQPGGKE-DAPAAEGKKKDA---- 134
+ + + E+ QP E E G QP ++ +AP AEG+ ++A
Sbjct: 1957 ESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 135 ---GAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTA------AEM 185
G EA+ EAQ + E + A E D + A E E Q A AE
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076
Query: 186 KPLGTTENVLTLQIAGELQPQG-------TVGKDEQAPLLETISKENESPEILEGSQFVE 238
+ +E+V + GE QP+ G+ ++A +E E E+ EG + E
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAPE 2136
Query: 239 TAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQ 298
E Q ++ G E Q E P+ E ++ + E+ + PE G +
Sbjct: 2137 AEGEAQPESE-GVEAQDAEGEAQPES----EGIEAQEAEEEAQPELEGVEAPEAEG---E 2188
Query: 299 IQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAE 358
QPE +E P EA +E + + EE Q E E E E + E + SEG E
Sbjct: 2189 AQPES--EGIEAPEAEGEAQPELEGVEAPEAEEEAQP-EPEGVETPEAEGEAQPESEG-E 2244
Query: 359 TKEEETG 365
T+ E+ G
Sbjct: 2245 TQGEKKG 2251
Score = 58.9 bits (141), Expect = 7e-09
Identities = 67/272 (24%), Positives = 114/272 (41%), Gaps = 48/272 (17%)
Query: 37 AQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVK-------------PLQE-- 81
AQP+ + + +G +E QK + A+P ++GV+ +QE
Sbjct: 2016 AQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE 2075
Query: 82 ---QPLAKDV------------APGRDATDQSGSTEKTQPGEGLEESGPPQPGGKE-DAP 125
P ++DV + G +A + G +K + E E G QP + +AP
Sbjct: 2076 GEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEAP 2135
Query: 126 AAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEM 185
AEG+ + G EA+ +G A+ PE++G Q A E+++ +E E P+ E
Sbjct: 2136 EAEGEAQPESEGVEAQDAEGEAQ-----PESEGIEAQEA-EEEAQPELEGVEAPEAEGEA 2189
Query: 186 KPLGTTENVLTLQIAGELQP-----QGTVGKDEQAPL---LETISKENESPEILEGSQFV 237
+P +E + + GE QP + ++E P +ET E E+ EG
Sbjct: 2190 QP--ESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGETQG 2247
Query: 238 ETAEEQQLQATLGK-EEQPQLLERIPKENVTP 268
E Q+ G+ EE + +P++ TP
Sbjct: 2248 EKKGSPQVSLGDGQSEEASESSSPVPEDRPTP 2279
Score = 53.9 bits (128), Expect = 2e-07
Identities = 74/304 (24%), Positives = 114/304 (37%), Gaps = 34/304 (11%)
Query: 89 APGRDATDQSGSTEKTQPGEGLEESGPPQPGGKE-DAPAAEGKKKDAGAGTEAESLKGNA 147
A G + G G+ E G QP ++ +AP AEG+ + E +
Sbjct: 1840 AEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV 1899
Query: 148 EAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQG 207
+ + G EA +A E +S+ A+E + +E E + G+ QP+
Sbjct: 1900 QPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEA-AQEAEGQTQPES 1958
Query: 208 TVGKDEQAPLLETISKENESPEILEGSQFVETA------EEQQLQATLGKEEQPQLLERI 261
V + ++A E E+E E LE + A E + ++A + E + E
Sbjct: 1959 EVIESQEAE--EEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEA 2016
Query: 262 PKENVTPEVLDRSQLVEKPVMNDPFHKT-----PEGPG------NMEQIQPEGIVGSME- 309
E+ E +S+ E + KT PE G E + EG V E
Sbjct: 2017 QPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEG 2076
Query: 310 --HP------ARNVEAGAYVEM--IRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAET 359
HP A+ E A E + + E Q+ EG E ET+ E + SEG E
Sbjct: 2077 EAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGI--EAPETEGEAQPESEGIEA 2134
Query: 360 KEEE 363
E E
Sbjct: 2135 PEAE 2138
Score = 52.4 bits (124), Expect = 7e-07
Identities = 76/280 (27%), Positives = 113/280 (40%), Gaps = 51/280 (18%)
Query: 102 EKTQPGEGLEESGPP--QPGGKED---APAAEGKKKDAGA-----GTEAESLKGNAEAQP 151
E Q GEG+ E G Q G ED AA G +D G G EA +G A+ +
Sbjct: 1789 EAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPES 1848
Query: 152 LG---PEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGT 208
G PEA+G +A E ++ E E P+ E +P +E+V T + E+QP+
Sbjct: 1849 EGVEAPEAEGDAQEA--EGEAQPESEDVEAPEAEGEAQP--ESEDVETPEAEWEVQPES- 1903
Query: 209 VGKDEQAPLLETISK-ENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVT 267
+ +AP E ++ E ES E LE E +E + + +E + E +
Sbjct: 1904 --EGAEAPEAEKEAQPETESVEALE----TEGEDEPESEGAEAQEAEEAAQEAEGQTQPE 1957
Query: 268 PEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGI-VGSMEHPARNVEAGAYVEMIRS 326
EV++ SQ E E+ QPE V ++E EA +
Sbjct: 1958 SEVIE-SQEAE------------------EEAQPESEDVEALEVEVETQEAEGEAQ---- 1994
Query: 327 IHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGE 366
ED GE E + E + S+G E + + GE
Sbjct: 1995 --PESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGE 2032
Score = 32.7 bits (73), Expect = 0.54
Identities = 34/138 (24%), Positives = 57/138 (41%), Gaps = 21/138 (15%)
Query: 51 DGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLA-KDVAPGRDATDQSGSTEKTQPGEG 109
+G Q+E L++++ + G + LQE+ + ++V G + Q + E EG
Sbjct: 1345 EGEGQQEEEAQLEEIEET------GGEGLQEEGVQLEEVKEGPEGGLQGEALE-----EG 1393
Query: 110 LEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDS 169
L+E G P+ G +E D KG+ E P+ E G+ +A +
Sbjct: 1394 LKEEGLPEEGSVHGQELSEASSPDG---------KGSQEDDPVQEEEAGRASASAEPCPA 1444
Query: 170 LRAVEVTENPQTAAEMKP 187
E TE P +E P
Sbjct: 1445 EGTEEPTEPPSHLSETDP 1462
Score = 31.2 bits (69), Expect = 1.6
Identities = 65/320 (20%), Positives = 114/320 (35%), Gaps = 41/320 (12%)
Query: 77 KPLQEQPLAKDVAPGRDATDQS---GSTEK-TQPGEGLEESGPPQPGGKEDAPAAEGKKK 132
+P Q + + PG+D + GS++ Q GEG+ + P+ G +APA G +
Sbjct: 1005 EPAQAGQQSLEGDPGQDPEPEGALLGSSDTGPQSGEGVPQGAAPE--GVSEAPAEAGADR 1062
Query: 133 DAGAGTEA----------------ESLKGNAEAQPLG------PEAKGQPLQAAVEKDSL 170
+A AG +L G+ + +P P A+ A L
Sbjct: 1063 EAPAGCRVSLRALPGRVSASTQIMRALMGSKQGRPSSVPEVSRPMARRLSCSAGALITCL 1122
Query: 171 RAVEVTE----NPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENE 226
++++ E +P + K + +L+ I+ +L P VG+D+ L ++
Sbjct: 1123 ASLQLFEEDLGSPASKVRFKDSPRYQELLS--ISKDLWPGCDVGEDQLDSGLWELTWSQA 1180
Query: 227 SPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPF 286
P++ + + +P V ++L K P
Sbjct: 1181 LPDLGSHAMTENFTPTSSSGVDISSGSGGSGESSVPCAMDGTLVTQGTELPLKTSNQRPD 1240
Query: 287 HKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVET 346
+T E PG++E Q + N A A + E+QR + E
Sbjct: 1241 SRTYESPGDLENQQQCCFPTFL-----NARACACATNEDEAERDSEEQRASSNLEQLAEN 1295
Query: 347 DMENEKVSEGAETKEEETGE 366
++ E E ETKE GE
Sbjct: 1296 TVQEEVQLE--ETKEGTEGE 1313
Score = 29.6 bits (65), Expect = 4.6
Identities = 33/134 (24%), Positives = 57/134 (42%), Gaps = 19/134 (14%)
Query: 47 ESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQP 106
E+ D QR S L+ AE T L+E K+ G +++ E+T+
Sbjct: 1275 EAERDSEEQRAS----SNLEQLAENTVQEEVQLEE---TKEGTEGEGLQEEAVQLEETKT 1327
Query: 107 GEGLEESG--------PPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEA-- 156
EGL+E G G +E+ E ++ G G + E ++ E GPE
Sbjct: 1328 EEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQ--LEEVKEGPEGGL 1385
Query: 157 KGQPLQAAVEKDSL 170
+G+ L+ ++++ L
Sbjct: 1386 QGEALEEGLKEEGL 1399
>gi|27262628 nuclear autoantigenic sperm protein isoform 2 [Homo
sapiens]
Length = 788
Score = 55.1 bits (131), Expect = 1e-07
Identities = 87/369 (23%), Positives = 139/369 (37%), Gaps = 65/369 (17%)
Query: 47 ESTVDGN--VQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAP----------GRDA 94
ES V+ N + E+R L++ A K +++ LAK GR+
Sbjct: 126 ESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGRED 185
Query: 95 TDQSGSTEKTQPGEGL----------EESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLK 144
D S S E+ Q L E G P G +A GK + E E
Sbjct: 186 MDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSV 245
Query: 145 GNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTE------------ 192
+ Q E GQ Q V V + E P+ +E +P+ T E
Sbjct: 246 SGTDVQEECREKGGQEKQGEV------IVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAES 299
Query: 193 ---NVLTLQIAGELQPQGTVGKDE----QAPLLETISKE----NESPEILEGSQFVETAE 241
V + + G+ +P+ V E +A L + + +E ESPE+ E AE
Sbjct: 300 LDPTVKPVDVGGD-EPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVT-----TEAAE 353
Query: 242 EQQLQATLGKEEQP-QLLERIPKENVT--PEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQ 298
++A E+P Q +PK+ P V+ +E + +T +G G E+
Sbjct: 354 ASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEK 413
Query: 299 IQPEGIVGSMEHPARNVE----AGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVS 354
++ + +V S E +VE AG V+ + E+ + + ET E++
Sbjct: 414 VRAK-LVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMK 472
Query: 355 EGAETKEEE 363
EG ET+ E
Sbjct: 473 EGEETEGSE 481
>gi|27262634 nuclear autoantigenic sperm protein isoform 1 [Homo
sapiens]
Length = 790
Score = 55.1 bits (131), Expect = 1e-07
Identities = 87/369 (23%), Positives = 139/369 (37%), Gaps = 65/369 (17%)
Query: 47 ESTVDGN--VQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAP----------GRDA 94
ES V+ N + E+R L++ A K +++ LAK GR+
Sbjct: 128 ESLVENNDNIDEEAREELREQVYDAMGEKEEAKKTEDKSLAKPETDKEQDSEMEKGGRED 187
Query: 95 TDQSGSTEKTQPGEGL----------EESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLK 144
D S S E+ Q L E G P G +A GK + E E
Sbjct: 188 MDISKSAEEPQEKVDLTLDWLTETSEEAKGGAAPEGPNEAEVTSGKPEQEVPDAEEEKSV 247
Query: 145 GNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTE------------ 192
+ Q E GQ Q V V + E P+ +E +P+ T E
Sbjct: 248 SGTDVQEECREKGGQEKQGEV------IVSIEEKPKEVSEEQPVVTLEKQGTAVEVEAES 301
Query: 193 ---NVLTLQIAGELQPQGTVGKDE----QAPLLETISKE----NESPEILEGSQFVETAE 241
V + + G+ +P+ V E +A L + + +E ESPE+ E AE
Sbjct: 302 LDPTVKPVDVGGD-EPEEKVVTSENEAGKAVLEQLVGQEVPPAEESPEVT-----TEAAE 355
Query: 242 EQQLQATLGKEEQP-QLLERIPKENVT--PEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQ 298
++A E+P Q +PK+ P V+ +E + +T +G G E+
Sbjct: 356 ASAVEAGSEVSEKPGQEAPVLPKDGAVNGPSVVGDQTPIEPQTSIERLTETKDGSGLEEK 415
Query: 299 IQPEGIVGSMEHPARNVE----AGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVS 354
++ + +V S E +VE AG V+ + E+ + + ET E++
Sbjct: 416 VRAK-LVPSQEETKLSVEESEAAGDGVDTKVAQGATEKSPEDKVQIAANEETQEREEQMK 474
Query: 355 EGAETKEEE 363
EG ET+ E
Sbjct: 475 EGEETEGSE 483
>gi|21493022 A kinase (PRKA) anchor protein 12 isoform 1 [Homo
sapiens]
Length = 1782
Score = 49.3 bits (116), Expect = 6e-06
Identities = 83/377 (22%), Positives = 151/377 (40%), Gaps = 45/377 (11%)
Query: 11 AGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAE 70
AGD + PS+ + E S E + +P+ L RE + E PP + + E
Sbjct: 212 AGDH-KDPSLGAGEAASKESEPKQSTEKPE-ETLKREQS-----HAEISPPAESGQAVEE 264
Query: 71 PTANGVKPLQEQPLAKDVAPGRDATDQSGSTEK---TQPGEGLEESGPPQPGGKEDAPAA 127
G + +++P +P T ++GST K TQ G + + +++ A+
Sbjct: 265 CKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEAS 324
Query: 128 EGKK----------KDAGAGTEAESLKGNAEAQPLGP-EAKGQP-LQAAVEKDSLRAVEV 175
E KK +D A +E L + +A P P E+ +P L A EK L + E
Sbjct: 325 EKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQ 384
Query: 176 TENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQ 235
Q +E KP V +I E+ + V + + + E E + E+ E +
Sbjct: 385 VSGSQGPSEEKPAPLATEVFDEKI--EVHQEEVVAEVHVSTVEE--RTEEQKTEVEETAG 440
Query: 236 FVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGN 295
V E ++ A + E + L ++ + V+ E D +Q + P K P
Sbjct: 441 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGE--DPTQGADL----SPDEKVLSKP-- 492
Query: 296 MEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGET------GEKVETDME 349
PEG+V +E + ++ + T+ +++ G+ G E+
Sbjct: 493 -----PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEH 547
Query: 350 NEKVSEGAETKEEETGE 366
+ ++ +++EE+ GE
Sbjct: 548 TQVPADSPDSQEEQKGE 564
Score = 39.3 bits (90), Expect = 0.006
Identities = 64/288 (22%), Positives = 106/288 (36%), Gaps = 47/288 (16%)
Query: 107 GEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVE 166
G E+ P QP PA + + +G G AE+ P+ P AA +
Sbjct: 4 GSSTEQRSPEQPPEGSSTPA---EPEPSGGGPSAEA----------APDTTADPAIAASD 50
Query: 167 KDS--LRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKE 224
+ L+ AE L E L Q G L QG + E+ ++ T +
Sbjct: 51 PATKLLQKNGQLSTINGVAEQDELSLQEGDLNGQ-KGALNGQGALNSQEEEEVIVTEVGQ 109
Query: 225 NESPEILEGSQFVETAEEQQLQATL---GKEEQPQLLERIPKENVTPEVLDRSQLVEKPV 281
+S ++ + E A + + + G+EE P+++E+IP E L +Q E
Sbjct: 110 RDSEDVSKRDSDKEMATKSAVVHDITDDGQEETPEIIEQIPSSESNLEEL--TQPTESQA 167
Query: 282 MNDPFHKT--------------PEGPGNMEQI-----QPEGIVGSMEHPARNVEAGAYV- 321
+ F K E P ++ + + EG G+ +H ++ AG
Sbjct: 168 NDIGFKKVFKFVGFKFTVKKDKTEKPDTVQLLTVKKDEGEGAAGAGDHKDPSLGAGEAAS 227
Query: 322 ---EMIRSIHTNEEDQRIE---GETGEKVETDMENEKVSEGAETKEEE 363
E +S EE + E E E+ E+ E E K+E+
Sbjct: 228 KESEPKQSTEKPEETLKREQSHAEISPPAESGQAVEECKEEGEEKQEK 275
Score = 34.3 bits (77), Expect = 0.19
Identities = 59/297 (19%), Positives = 111/297 (37%), Gaps = 50/297 (16%)
Query: 101 TEKTQPGEGLEESGPPQPGGKEDAPAA-----EGKKKDAGAGTEAESLKGNAEAQPLGPE 155
+E + G G+E S P GKE++ + G++K G + ++ +A P G
Sbjct: 780 SEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQA--PVEDAGPTGAN 837
Query: 156 AKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQA 215
+ A V AVE E + K E +++ EL + Q
Sbjct: 838 EDDSDVPAVVPLSEYDAVE-REKMEAQQAQKSAEQPEQKAATEVSKEL-------SESQV 889
Query: 216 PLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKEN--VTPEVLDR 273
++ + + +G++ EE+ +P LE++ E +T EVL+R
Sbjct: 890 HMM--------AAAVADGTRAATIIEERSPSWISASVTEP--LEQVEAEAALLTEEVLER 939
Query: 274 SQLVEK--PVMNDPFHKTPEGPGNM----EQIQPEGIVGSMEHPARNVEAG--------- 318
+ E+ P + +P + E G+ ++ PE + + E G
Sbjct: 940 EVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEET 999
Query: 319 -----AYVEMIRSIHTNEED---QRIEGETGEKVETDMENEKVSEGAETKEEETGEV 367
A ++ S T EE Q +EG + E + ++V + K +E ++
Sbjct: 1000 TEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQL 1056
Score = 33.9 bits (76), Expect = 0.24
Identities = 82/372 (22%), Positives = 138/372 (37%), Gaps = 39/372 (10%)
Query: 29 AEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDV 88
A+E S P P LG+E V +Q +S L +AE + + +
Sbjct: 1386 AKEVSSLEGSPPP-CLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETL 1444
Query: 89 AP-GRDATDQSGSTEKTQ-----PGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAE- 141
P G + S+EK + PGE +GP + KK + E E
Sbjct: 1445 EPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEK 1504
Query: 142 --SLKGNAEA---QPLGPEAKG-------QPLQAAVEKDSLRAVEVTENPQTAAEMKPLG 189
SLK ++ Q E K +P +E ++ + V QTA +
Sbjct: 1505 TTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQ--FV 1562
Query: 190 TTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEI-LEGSQFVETAEEQQLQAT 248
TE T + ELQ Q V K + + KE E P+ + + +A+E+
Sbjct: 1563 RTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTA 1622
Query: 249 LGK------EEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDP------FHKTPEGPGNM 296
+G+ ++ + E+ V ++ QL E + ++ PE G+
Sbjct: 1623 VGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGH- 1681
Query: 297 EQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGE-TGEKVETDMENEKVSE 355
+ E I S+ P + E G V+ + ++ D G T E +T+ +K E
Sbjct: 1682 -ALLAERIEKSLVEPKED-EKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE 1739
Query: 356 GAETKEEETGEV 367
A+ E + G+V
Sbjct: 1740 DAQEVELQEGKV 1751
>gi|21493024 A kinase (PRKA) anchor protein 12 isoform 2 [Homo
sapiens]
Length = 1684
Score = 49.3 bits (116), Expect = 6e-06
Identities = 83/377 (22%), Positives = 151/377 (40%), Gaps = 45/377 (11%)
Query: 11 AGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAE 70
AGD + PS+ + E S E + +P+ L RE + E PP + + E
Sbjct: 114 AGDH-KDPSLGAGEAASKESEPKQSTEKPE-ETLKREQS-----HAEISPPAESGQAVEE 166
Query: 71 PTANGVKPLQEQPLAKDVAPGRDATDQSGSTEK---TQPGEGLEESGPPQPGGKEDAPAA 127
G + +++P +P T ++GST K TQ G + + +++ A+
Sbjct: 167 CKEEGEEKQEKEPSKSAESPTSPVTSETGSTFKKFFTQGWAGWRKKTSFRKPKEDEVEAS 226
Query: 128 EGKK----------KDAGAGTEAESLKGNAEAQPLGP-EAKGQP-LQAAVEKDSLRAVEV 175
E KK +D A +E L + +A P P E+ +P L A EK L + E
Sbjct: 227 EKKKEQEPEKVDTEEDGKAEVASEKLTASEQAHPQEPAESAHEPRLSAEYEKVELPSEEQ 286
Query: 176 TENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQ 235
Q +E KP V +I E+ + V + + + E E + E+ E +
Sbjct: 287 VSGSQGPSEEKPAPLATEVFDEKI--EVHQEEVVAEVHVSTVEE--RTEEQKTEVEETAG 342
Query: 236 FVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGN 295
V E ++ A + E + L ++ + V+ E D +Q + P K P
Sbjct: 343 SVPAEELVEMDAEPQEAEPAKELVKLKETCVSGE--DPTQGADL----SPDEKVLSKP-- 394
Query: 296 MEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGET------GEKVETDME 349
PEG+V +E + ++ + T+ +++ G+ G E+
Sbjct: 395 -----PEGVVSEVEMLSSQERMKVQGSPLKKLFTSTGLKKLSGKKQKGKRGGGDEESGEH 449
Query: 350 NEKVSEGAETKEEETGE 366
+ ++ +++EE+ GE
Sbjct: 450 TQVPADSPDSQEEQKGE 466
Score = 34.3 bits (77), Expect = 0.19
Identities = 59/297 (19%), Positives = 111/297 (37%), Gaps = 50/297 (16%)
Query: 101 TEKTQPGEGLEESGPPQPGGKEDAPAA-----EGKKKDAGAGTEAESLKGNAEAQPLGPE 155
+E + G G+E S P GKE++ + G++K G + ++ +A P G
Sbjct: 682 SEDSIAGSGVEHSTPDTEPGKEESWVSIKKFIPGRRKKRPDGKQEQA--PVEDAGPTGAN 739
Query: 156 AKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQA 215
+ A V AVE E + K E +++ EL + Q
Sbjct: 740 EDDSDVPAVVPLSEYDAVE-REKMEAQQAQKSAEQPEQKAATEVSKEL-------SESQV 791
Query: 216 PLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKEN--VTPEVLDR 273
++ + + +G++ EE+ +P LE++ E +T EVL+R
Sbjct: 792 HMM--------AAAVADGTRAATIIEERSPSWISASVTEP--LEQVEAEAALLTEEVLER 841
Query: 274 SQLVEK--PVMNDPFHKTPEGPGNM----EQIQPEGIVGSMEHPARNVEAG--------- 318
+ E+ P + +P + E G+ ++ PE + + E G
Sbjct: 842 EVIAEEEPPTVTEPLPENREARGDTVVSEAELTPEAVTAAETAGPLGAEEGTEASAAEET 901
Query: 319 -----AYVEMIRSIHTNEED---QRIEGETGEKVETDMENEKVSEGAETKEEETGEV 367
A ++ S T EE Q +EG + E + ++V + K +E ++
Sbjct: 902 TEMVSAVSQLTDSPDTTEEATPVQEVEGGVPDIEEQERRTQEVLQAVAEKVKEESQL 958
Score = 33.9 bits (76), Expect = 0.24
Identities = 82/372 (22%), Positives = 138/372 (37%), Gaps = 39/372 (10%)
Query: 29 AEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDV 88
A+E S P P LG+E V +Q +S L +AE + + +
Sbjct: 1288 AKEVSSLEGSPPP-CLGQEEAVCTKIQVQSSEASFTLTAAAEEEKVLGETANILETGETL 1346
Query: 89 AP-GRDATDQSGSTEKTQ-----PGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAE- 141
P G + S+EK + PGE +GP + KK + E E
Sbjct: 1347 EPAGAHLVLEEKSSEKNEDFAAHPGEDAVPTGPDCQAKSTPVIVSATTKKGLSSDLEGEK 1406
Query: 142 --SLKGNAEA---QPLGPEAKG-------QPLQAAVEKDSLRAVEVTENPQTAAEMKPLG 189
SLK ++ Q E K +P +E ++ + V QTA +
Sbjct: 1407 TTSLKWKSDEVDEQVACQEVKVSVAIEDLEPENGILELETKSSKLVQNIIQTAVDQ--FV 1464
Query: 190 TTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEI-LEGSQFVETAEEQQLQAT 248
TE T + ELQ Q V K + + KE E P+ + + +A+E+
Sbjct: 1465 RTEETATEMLTSELQTQAHVIKADSQDAGQETEKEGEEPQASAQDETPITSAKEESESTA 1524
Query: 249 LGK------EEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDP------FHKTPEGPGNM 296
+G+ ++ + E+ V ++ QL E + ++ PE G+
Sbjct: 1525 VGQAHSDISKDMSEASEKTMTVEVEGSTVNDQQLEEVVLPSEEEGGGAGTKSVPEDDGH- 1583
Query: 297 EQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGE-TGEKVETDMENEKVSE 355
+ E I S+ P + E G V+ + ++ D G T E +T+ +K E
Sbjct: 1584 -ALLAERIEKSLVEPKED-EKGDDVDDPENQNSALADTDASGGLTKESPDTNGPKQKEKE 1641
Query: 356 GAETKEEETGEV 367
A+ E + G+V
Sbjct: 1642 DAQEVELQEGKV 1653
>gi|56606114 trichohyalin-like 1 [Homo sapiens]
Length = 904
Score = 48.1 bits (113), Expect = 1e-05
Identities = 74/318 (23%), Positives = 116/318 (36%), Gaps = 35/318 (11%)
Query: 54 VQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVA-------PGRDATDQSGSTEKTQP 106
+QRE P Q + + A Q+ +KDV PG+DA T+
Sbjct: 293 LQREDEPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGE 352
Query: 107 GEGLEESGPPQPGGKE--DAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAA 164
E + Q E D P G + G+E ++ + + GPEA G Q
Sbjct: 353 PEDYGRTSETQEKECETKDLPVQYGSRN----GSETSDMR-DERKERRGPEAHGTAGQK- 406
Query: 165 VEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLE-TISK 223
E+D V E + + L + E Q + G D+ P LE T
Sbjct: 407 -ERDRKTRPLVLETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVS 465
Query: 224 ENESPEILEGS--QFVETAEEQQLQATLGKEEQPQLLERIPKENV---TPEVLDRSQLVE 278
E+ EG+ FV + + TLG E+ Q L + K++V T Q VE
Sbjct: 466 GEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQPVE 525
Query: 279 K------PVMNDPFHKTPEG----PGNMEQIQPEGIVGSMEHPAR---NVEAGAYVEMIR 325
+ PF ++ EG P ++ + + E P + + + E ++
Sbjct: 526 EEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQHGESVQ 585
Query: 326 SIHTNEEDQRIEGETGEK 343
H N D + +G GEK
Sbjct: 586 GGHNNNPDTQRQGTPGEK 603
>gi|27894378 chloride intracellular channel 6 [Homo sapiens]
Length = 686
Score = 45.1 bits (105), Expect = 1e-04
Identities = 78/314 (24%), Positives = 119/314 (37%), Gaps = 44/314 (14%)
Query: 88 VAPGRDATDQSGSTEKTQPGE----GLEESGPPQPGGKEDAPAAEGKKKDAGA-----GT 138
VAPG + + +PGE G E GP G E+AP K+AG G
Sbjct: 10 VAPGPQGPPEVPAPLAERPGEPGAAGGEAEGPEGSEGAEEAPRGAAAVKEAGGGGPDRGP 69
Query: 139 EAES-----LKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTEN 193
EAE+ G EA+ PE P Q E + VE +P A+ +P G +
Sbjct: 70 EAEARGTRGAHGETEAEEGAPEGAEVP-QGGEETSGAQQVE-GASPGRGAQGEPRGEAQR 127
Query: 194 VLTLQIAGELQ---------PQGTV------GKDEQAPLLETISKENESPEILEGSQFVE 238
A E Q P+G+ D + PL + I E + + +E V
Sbjct: 128 EPEDSAAPERQEEAEQRPEVPEGSASGEAGDSVDAEGPLGDNIEAEGPAGDSVEAEGRVG 187
Query: 239 TAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQ 298
+ + + A + + L + I E + +D V V EGP +
Sbjct: 188 DSVDAEGPAGDSVDAEGPLGDNIQAEGPAGDSVDAEGRVGDSV-------DAEGPAG-DS 239
Query: 299 IQPEGIVG-SME--HPARN-VEAGAYV-EMIRSIHTNEEDQRIEGETGEKVETDMENEKV 353
+ EG VG S+E PA + VEAG + + + + EG G E ++
Sbjct: 240 VDAEGRVGDSVEAGDPAGDGVEAGVPAGDSVEAEGPAGDSMDAEGPAGRARRVSGEPQQS 299
Query: 354 SEGAETKEEETGEV 367
+G+ + + E EV
Sbjct: 300 GDGSLSPQAEAIEV 313
>gi|118421089 chromodomain helicase DNA binding protein 2 isoform 1
[Homo sapiens]
Length = 1828
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/277 (21%), Positives = 104/277 (37%), Gaps = 21/277 (7%)
Query: 85 AKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLK 144
A + A G D+ QS S + + PG G G E ++E + + E+ES
Sbjct: 24 ASEEASGSDSGSQSESEQGSDPGSG---------HGSESNSSSESSESQS----ESESES 70
Query: 145 GNAEAQPLGPEAKGQPLQAAVEKDSLRAVEV--TENPQTAAEMKPLGTTENVLTLQIAGE 202
+++QP+ PEAK +P A +K+ + V+ E P + + + I E
Sbjct: 71 AGSKSQPVLPEAKEKP---ASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEE 127
Query: 203 LQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIP 262
G ++ + +E E E Q T+ E + + K +P +P
Sbjct: 128 ASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP 187
Query: 263 KENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVE 322
K V + + +K +D E P + + V E ++ +E
Sbjct: 188 KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIE 247
Query: 323 MIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAET 359
M ++Q+ ET EKV +K + GA T
Sbjct: 248 MTGE---GVDEQQDNSETIEKVLDSRLGKKGATGAST 281
>gi|110611184 chromodomain helicase DNA binding protein 2 isoform 2
[Homo sapiens]
Length = 501
Score = 44.7 bits (104), Expect = 1e-04
Identities = 60/277 (21%), Positives = 104/277 (37%), Gaps = 21/277 (7%)
Query: 85 AKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLK 144
A + A G D+ QS S + + PG G G E ++E + + E+ES
Sbjct: 24 ASEEASGSDSGSQSESEQGSDPGSG---------HGSESNSSSESSESQS----ESESES 70
Query: 145 GNAEAQPLGPEAKGQPLQAAVEKDSLRAVEV--TENPQTAAEMKPLGTTENVLTLQIAGE 202
+++QP+ PEAK +P A +K+ + V+ E P + + + I E
Sbjct: 71 AGSKSQPVLPEAKEKP---ASKKERIADVKKMWEEYPDVYGVRRSNRSRQEPSRFNIKEE 127
Query: 203 LQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIP 262
G ++ + +E E E Q T+ E + + K +P +P
Sbjct: 128 ASSGSESGSPKRRGQRQLKKQEKWKQEPSEDEQEQGTSAESEPEQKKVKARRPVPRRTVP 187
Query: 263 KENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVE 322
K V + + +K +D E P + + V E ++ +E
Sbjct: 188 KPRVKKQPKTQRGKRKKQDSSDEDDDDDEAPKRQTRRRAAKNVSYKEDDDFETDSDDLIE 247
Query: 323 MIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAET 359
M ++Q+ ET EKV +K + GA T
Sbjct: 248 MTGE---GVDEQQDNSETIEKVLDSRLGKKGATGAST 281
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 43.1 bits (100), Expect = 4e-04
Identities = 81/352 (23%), Positives = 137/352 (38%), Gaps = 58/352 (16%)
Query: 70 EPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEG 129
EP A + ++ K AP + ++ G E+ EG EE G K D G
Sbjct: 498 EPEAEEEEVAAKKSPVKATAP--EVKEEEGEKEEE---EGQEEEEEEDEGAKSDQAEEGG 552
Query: 130 KKKDAGAGTE-AESLKGNAEAQPLGPEAKGQPLQAAVEK-------DSLRAVEVTENPQT 181
+K+ + E E +G EA+ G EA+ + + EK + L A E P+
Sbjct: 553 SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 612
Query: 182 AAEMKPLGTTENV-------LTLQIAGELQ-PQGTVGKDEQAPLLET-ISKENESPEILE 232
A P E ++ G+ P+ V + ++P+ ++ + ++ +SP +
Sbjct: 613 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP--VS 670
Query: 233 GSQFVETA---------EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMN 283
S E A EE + +A +GK EQ + E+ KE E +++ + EKP +
Sbjct: 671 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE--EKP-KD 727
Query: 284 DPFHKTPEGPGNMEQI------------------QPEG--IVGSMEHPARNVEAGAYVEM 323
P K E P E + + EG + E E G+ E
Sbjct: 728 VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 787
Query: 324 IR--SIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAA 373
+ + +ED + GE K E + E ++ G E ++ +DLS A
Sbjct: 788 SDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPA 839
Score = 38.5 bits (88), Expect = 0.010
Identities = 76/351 (21%), Positives = 145/351 (41%), Gaps = 47/351 (13%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAE--PTANGVKPLQEQPLAKDVAPGRDATDQSGSTEK 103
+E + ++E P ++ +V+A+ P ++E+ K+ ++ G E+
Sbjct: 485 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE--------EEEGQEEE 536
Query: 104 TQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAG-TEAESLKGNAEAQPLGPEAKGQPLQ 162
+ EG + S + GG E ++E ++ + G TEAE+ AEA+ + + +
Sbjct: 537 EEEDEGAK-SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE--EKKVEEKSE 593
Query: 163 AAVEKDSLRAVEVTENPQTAAEMKPLGTTEN-------VLTLQIAGELQ-PQGTVGKDEQ 214
K+ L A E P+ A P E ++ G+ P+ V + +
Sbjct: 594 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 653
Query: 215 APLLET-ISKENESP-------EILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENV 266
+P+ ++ + ++ +SP E + EE + +A +GK EQ + E+ KE
Sbjct: 654 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 713
Query: 267 TPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRS 326
E +++ + EKP + P K E P E + +V + ++E E +
Sbjct: 714 KEEKVEKKE--EKP-KDVPEKKKAESPVKEEAVAE--VVTITKSVKVHLEKETKEEG-KP 767
Query: 327 IHTNEEDQRIEGETGEKVETDMENEKVS-----------EGAETKEEETGE 366
+ +E ++ GE G + E + K S EG E E+ET E
Sbjct: 768 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE 818
Score = 32.3 bits (72), Expect = 0.71
Identities = 41/163 (25%), Positives = 63/163 (38%), Gaps = 26/163 (15%)
Query: 217 LLETISKENESPEILEG-----SQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVL 271
++E E+E E+ E + + +E++ +A KEE+P+ E EV
Sbjct: 456 IIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEE--------EVA 507
Query: 272 DRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNE 331
+ V+ P K EG E+ Q E + E G +E
Sbjct: 508 AKKSPVKATA---PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG----------SE 554
Query: 332 EDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT 374
++ E E GE+ E + E E E AE KEE+ E AT
Sbjct: 555 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 597
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 43.1 bits (100), Expect = 4e-04
Identities = 81/352 (23%), Positives = 137/352 (38%), Gaps = 58/352 (16%)
Query: 70 EPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEG 129
EP A + ++ K AP + ++ G E+ EG EE G K D G
Sbjct: 122 EPEAEEEEVAAKKSPVKATAP--EVKEEEGEKEEE---EGQEEEEEEDEGAKSDQAEEGG 176
Query: 130 KKKDAGAGTE-AESLKGNAEAQPLGPEAKGQPLQAAVEK-------DSLRAVEVTENPQT 181
+K+ + E E +G EA+ G EA+ + + EK + L A E P+
Sbjct: 177 SEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEK 236
Query: 182 AAEMKPLGTTENV-------LTLQIAGELQ-PQGTVGKDEQAPLLET-ISKENESPEILE 232
A P E ++ G+ P+ V + ++P+ ++ + ++ +SP +
Sbjct: 237 AKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSP--VS 294
Query: 233 GSQFVETA---------EEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMN 283
S E A EE + +A +GK EQ + E+ KE E +++ + EKP +
Sbjct: 295 KSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKE--EKP-KD 351
Query: 284 DPFHKTPEGPGNMEQI------------------QPEG--IVGSMEHPARNVEAGAYVEM 323
P K E P E + + EG + E E G+ E
Sbjct: 352 VPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEG 411
Query: 324 IR--SIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAA 373
+ + +ED + GE K E + E ++ G E ++ +DLS A
Sbjct: 412 SDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGLDLSPA 463
Score = 38.5 bits (88), Expect = 0.010
Identities = 76/351 (21%), Positives = 145/351 (41%), Gaps = 47/351 (13%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAE--PTANGVKPLQEQPLAKDVAPGRDATDQSGSTEK 103
+E + ++E P ++ +V+A+ P ++E+ K+ ++ G E+
Sbjct: 109 KEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAPEVKEEEGEKE--------EEEGQEEE 160
Query: 104 TQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAG-TEAESLKGNAEAQPLGPEAKGQPLQ 162
+ EG + S + GG E ++E ++ + G TEAE+ AEA+ + + +
Sbjct: 161 EEEDEGAK-SDQAEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKE--EKKVEEKSE 217
Query: 163 AAVEKDSLRAVEVTENPQTAAEMKPLGTTEN-------VLTLQIAGELQ-PQGTVGKDEQ 214
K+ L A E P+ A P E ++ G+ P+ V + +
Sbjct: 218 EVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGK 277
Query: 215 APLLET-ISKENESP-------EILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENV 266
+P+ ++ + ++ +SP E + EE + +A +GK EQ + E+ KE
Sbjct: 278 SPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAP 337
Query: 267 TPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRS 326
E +++ + EKP + P K E P E + +V + ++E E +
Sbjct: 338 KEEKVEKKE--EKP-KDVPEKKKAESPVKEEAVAE--VVTITKSVKVHLEKETKEEG-KP 391
Query: 327 IHTNEEDQRIEGETGEKVETDMENEKVS-----------EGAETKEEETGE 366
+ +E ++ GE G + E + K S EG E E+ET E
Sbjct: 392 LQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKE 442
Score = 32.3 bits (72), Expect = 0.71
Identities = 41/163 (25%), Positives = 63/163 (38%), Gaps = 26/163 (15%)
Query: 217 LLETISKENESPEILEG-----SQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVL 271
++E E+E E+ E + + +E++ +A KEE+P+ E EV
Sbjct: 80 IIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEE--------EVA 131
Query: 272 DRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNE 331
+ V+ P K EG E+ Q E + E G +E
Sbjct: 132 AKKSPVKATA---PEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGG----------SE 178
Query: 332 EDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSAAT 374
++ E E GE+ E + E E E AE KEE+ E AT
Sbjct: 179 KEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVAT 221
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 42.7 bits (99), Expect = 5e-04
Identities = 76/356 (21%), Positives = 128/356 (35%), Gaps = 48/356 (13%)
Query: 24 EHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQP 83
E + EE E+ + K G E +G + PP ++ +A P P++E+
Sbjct: 468 EEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEE---AASPEKEAKSPVKEE- 523
Query: 84 LAKDVAPGRDATDQSG-------STEKTQPGEGLEESGPPQ---PGGKEDAPAAEGKKKD 133
AK A + + S EK + E PP+ P +E AE K +
Sbjct: 524 -AKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPE 582
Query: 134 AGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTEN 193
E K AEA+ PE P++ + + V E ++ AE+K
Sbjct: 583 KAKSPAKEEAKSPAEAK--SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVK------- 633
Query: 194 VLTLQIAGELQPQGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEE 253
+ + K+E + S E E + E ++ AE + + K +
Sbjct: 634 --------SPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPE----KAK 681
Query: 254 QPQLLERIPKENVTPEVLDRSQLVEK---PVMNDPFHKTPE---GPGNMEQIQPEGIVGS 307
P E E V + ++ EK PV + K+PE P E PE
Sbjct: 682 SPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEA--KSPEKAKSPVKEEAKTPEKAKSP 739
Query: 308 MEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEE 363
++ A++ E E +++ E +T K E +K E A++ +E
Sbjct: 740 VKEEAKSPEKAKSPEKAKTLDVKSP----EAKTPAKEEARSPADKFPEKAKSPVKE 791
Score = 35.8 bits (81), Expect = 0.064
Identities = 74/319 (23%), Positives = 126/319 (39%), Gaps = 36/319 (11%)
Query: 54 VQRESRPPLQK---LKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGL 110
V+ E++ P + +K A+ P++E+ + + A +++ S EK +
Sbjct: 670 VKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKS-PVKEEAKSPEKAKSPVKE 728
Query: 111 EESGPPQPGG--KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKD 168
E P + KE+A + E K A T +K P EA+ P EK
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAKSPEKAKTL--DVKSPEAKTPAKEEARS-PADKFPEKA 785
Query: 169 SLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENESP 228
E ++P+ A PL P+ + K E+ +++ KE E P
Sbjct: 786 KSPVKEEVKSPEKAKS--PLKEDAKA----------PEKEIPKKEE---VKSPVKEEEKP 830
Query: 229 EILEGSQFVETAEEQQLQATLGKEEQ--PQLLERIPKENVTPEVLDRSQ-LVEKPVMNDP 285
+ ++ + + AEE++ AT EE+ + E KE P+V ++ + VEKP +
Sbjct: 831 QEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKV 890
Query: 286 FHKTPEGPGNMEQIQPEGIVGSMEHPAR-NVEAGAYVEMIRSIHTNEEDQRIEGETGEKV 344
K E + PE E PA+ V+ A + + E D E +
Sbjct: 891 EAKKEEAEDKKKVPTPE-----KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPA 945
Query: 345 ETDMENEKVSEGAETKEEE 363
E + E E +TKEE+
Sbjct: 946 E---KKEAAPEKKDTKEEK 961
Score = 33.1 bits (74), Expect = 0.42
Identities = 61/356 (17%), Positives = 135/356 (37%), Gaps = 39/356 (10%)
Query: 41 PHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGS 100
P L + +V +++ +S ++ ++ S + T + +E + ++V + +
Sbjct: 423 PEGLPKIPSVSTHIKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEE 482
Query: 101 TEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDA-------------GAGTEAESLKGNA 147
++ + GE E G + A A +K+A E E K A
Sbjct: 483 GKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPA 542
Query: 148 EAQ-------PLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIA 200
E + P EAK P + EK+ ++ ++P+ A K E +
Sbjct: 543 EVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKA---KSPAKEEAKSPAEAK 599
Query: 201 GELQPQGTVGKDEQAP--LLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLL 258
+ + V ++ ++P + +E +SP ++ + ++ +++ ++ K + P+
Sbjct: 600 SPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSP-EKAKSPEKE 658
Query: 259 ERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVE-- 316
E E V ++ EK + P E PE ++ A++ E
Sbjct: 659 EAKSPEKAKSPVKAEAKSPEK----------AKSPVKAEAKSPEKAKSPVKEEAKSPEKA 708
Query: 317 AGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSEGAETKEEETGEVVDLSA 372
E +S + + E +T EK ++ ++ E S + K E + +D+ +
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSP-EKAKSPEKAKTLDVKS 763
>gi|222537747 hypothetical protein LOC342979 [Homo sapiens]
Length = 673
Score = 42.4 bits (98), Expect = 7e-04
Identities = 44/165 (26%), Positives = 62/165 (37%), Gaps = 18/165 (10%)
Query: 30 EESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVA 89
EE + LG E ++ PL+ + E T K E+ L +
Sbjct: 472 EEKRGAEEEEVEEPLGVEKKGGEEEPEATKEPLEAERKGGEETLEAEKRGGEESLETEKT 531
Query: 90 PGR--DATDQSGSTEKTQP-GEGLEESGPPQPGGKEDAPAAEG---KKKDAGAGTEAESL 143
G D + GS E ++ E + E+GPP E P EG ++K GA E E +
Sbjct: 532 QGTEGDLNLEQGSREGSESQAEEMNEAGPPLEANTETRPEKEGPQPQEKPVGA-LEEEGV 590
Query: 144 KGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPL 188
K A+ GP PL A T P+ AE +PL
Sbjct: 591 KPQTAAEGQGPLGDATPLLAE-----------TPAPEQPAECQPL 624
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 42.4 bits (98), Expect = 7e-04
Identities = 65/276 (23%), Positives = 105/276 (38%), Gaps = 16/276 (5%)
Query: 91 GRDATDQS-GSTEKTQP-GEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAE 148
G + DQ G E+T+ GE EE G + G E+ ++++ G G E E E
Sbjct: 787 GEEEGDQGEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEE 846
Query: 149 AQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGT 208
+ E +G+ + E + E E E + G E GE + +
Sbjct: 847 GEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG------EGEGEEEEG 900
Query: 209 VGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTP 268
G+ E+ E +E E EG + EE++ + G++ + + E
Sbjct: 901 EGEGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGE-GEDGEGE------GEEEEG 953
Query: 269 EVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIH 328
E + E + + EG G E+ + EG E E G E
Sbjct: 954 EWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEG 1013
Query: 329 TNEEDQRIEGET-GEKVETDMENEKVSEGAETKEEE 363
EE+ +EGE GE+ E + E E+ E E +E+E
Sbjct: 1014 EEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE 1049
Score = 40.0 bits (92), Expect = 0.003
Identities = 64/266 (24%), Positives = 101/266 (37%), Gaps = 14/266 (5%)
Query: 102 EKTQPGEGLEESGPPQPGGKEDAPAAEGKKKD-AGAGTEAESLKGNAEAQPLGPEAKGQP 160
E+ + GEG EE + G+ + E KK++ AG + E E + E +G+
Sbjct: 748 EEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEE 807
Query: 161 LQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLET 220
+ E + VE + + E + G E + GE + + GK E+
Sbjct: 808 KEEGGEVEG-GEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEE----- 861
Query: 221 ISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKP 280
+E E E EG + EE++ + +E + + E + E + E
Sbjct: 862 -GEEGEGEE--EGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGE 918
Query: 281 VMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGET 340
+ + EG G E+ + EG G E E E EE+ EGE
Sbjct: 919 GKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEE--EGEGEGEEEGEGEGEE 976
Query: 341 GEKVETDMENEKVSEGAETKEEETGE 366
GE + E E EG E + EE GE
Sbjct: 977 GEGEGEEEEGE--GEGEEEEGEEEGE 1000
Score = 39.7 bits (91), Expect = 0.004
Identities = 65/268 (24%), Positives = 98/268 (36%), Gaps = 31/268 (11%)
Query: 99 GSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKG 158
G E +PGEG +E + K D E K+++ G E N E + G E G
Sbjct: 682 GRGEMERPGEGEKELAEKEEWKKRDGEEQEQKEREQGHQKER-----NQEMEEGGEEEHG 736
Query: 159 QPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLL 218
+ + +++ E + E K G E ++ GE + + K E
Sbjct: 737 EGEEEEGDRE--------EEEEKEGEGKEEGEGE-----EVEGEREKEEGERKKE----- 778
Query: 219 ETISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVE 278
E KE + E EG Q E + + T G+ E+ + + V +R + E
Sbjct: 779 ERAGKEEKGEE--EGDQ-----GEGEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 279 KPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEG 338
+ + + E G E+ + EG E G E E + EG
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEG 891
Query: 339 ETGEKVETDMENEKVSEGAETKEEETGE 366
E GE E + E E EG EEE GE
Sbjct: 892 E-GEGEEEEGEGEGEEEGEGEGEEEEGE 918
Score = 37.4 bits (85), Expect = 0.022
Identities = 63/262 (24%), Positives = 96/262 (36%), Gaps = 30/262 (11%)
Query: 91 GRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESL-KGNAEA 149
G + + E+ + GEG EE + G+E+ EG+++ G G E E +G E
Sbjct: 849 GEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEG 908
Query: 150 QPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTV 209
+ G E +G+ ++ E E + + G E GE + +
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEE-------GEWEGEEEE 961
Query: 210 GKDEQAPLLETISKENE---SPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENV 266
G+ E E +E E E EG E EE+ + G+EE E + V
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEV 1021
Query: 267 TPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEG----IVGSMEHPARNVEAGAYVE 322
EV + EG G E+ + EG G E RN E E
Sbjct: 1022 EGEVEG---------------EEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEEEEE 1066
Query: 323 MIRSIHTNEEDQRIEGETGEKV 344
EE++R +GE +KV
Sbjct: 1067 GKYQETGEEENERQDGEEYKKV 1088
Score = 37.0 bits (84), Expect = 0.029
Identities = 76/314 (24%), Positives = 115/314 (36%), Gaps = 46/314 (14%)
Query: 85 AKDVAPGR-DATDQSGST----------EKTQPGEGLEESGPPQPGGKEDAPAAEGKKKD 133
A+D GR D T + GS+ EK + +G E P G KE A E KK+D
Sbjct: 647 AEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGEKELAEKEEWKKRD 706
Query: 134 AGAGTEAESLKG-----NAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPL 188
+ E +G N E + G E G+ + +++ E + E K
Sbjct: 707 GEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDRE--------EEEEKEGEGKEE 758
Query: 189 GTTENVL--TLQIAGELQPQGTVGKDEQAPL-----------LETISKENESPEILEGSQ 235
G E V + GE + + GK+E+ E +E E +EG +
Sbjct: 759 GEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGEEKEEGGEVEGGE 818
Query: 236 FVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGN 295
E E++ + G+ E+ + E +E E + E+ + + EG G
Sbjct: 819 VEEGKGEREEEEEEGEGEEEEG-EGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGE 877
Query: 296 MEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQRIEGETGEKVETDMENEKVSE 355
E+ + EG G E E E EE+ EGE E E + E
Sbjct: 878 GEEEEGEG-EGEEEGEGEGEEEEGEGE-------GEEEGEGEGEEEEGEGKGEEEGEEGE 929
Query: 356 GAETKEEETGEVVD 369
G +EE GE D
Sbjct: 930 GEGEEEEGEGEGED 943
>gi|148727245 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 42.4 bits (98), Expect = 7e-04
Identities = 80/362 (22%), Positives = 138/362 (38%), Gaps = 36/362 (9%)
Query: 10 KAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSA 69
K GD + P T +S QPK + N+ + S P+Q K+
Sbjct: 48 KEGDIPKAPEETIQSKKEDLPKSSEKAIQPK----------ESNIPKSSAKPIQP-KLGN 96
Query: 70 EPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEG 129
P A+ VKP QP D+ + T QS +K + EE+ P+ G D P +
Sbjct: 97 IPKAS-VKP--SQPKEGDIPKAPEETIQS---KKEDLPKSSEEAIQPKEG---DIPKSSA 147
Query: 130 KKKDAGAGTEAE-SLKGNAEAQ---PLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEM 185
K G A+ S+K + + P PE QP + + K S + ++ A +
Sbjct: 148 KPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASV 207
Query: 186 KPLGTTENVLTLQIAGELQP-QGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQ 244
KP E ++ +QP +G + K + + +SPE E Q E +
Sbjct: 208 KPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPE--EAIQPKEGDIPKS 265
Query: 245 LQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGI 304
L+ + +E + + P+E + P+ D + E+ + P+ P Q + I
Sbjct: 266 LEEAIQPKEGD--IPKSPEETIQPKKGDIPKSPEEAIQPKE-GDIPKSPKQAIQPKEGDI 322
Query: 305 VGSMEHPARNVEAGAYVEMIRSIHTNEED------QRIEGETGEKVETDMENEKVSEGAE 358
S+E E +I E+D + + G+ ++ + E + EG +
Sbjct: 323 PKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDK 382
Query: 359 TK 360
K
Sbjct: 383 VK 384
Score = 31.2 bits (69), Expect = 1.6
Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 12/174 (6%)
Query: 111 EESGPPQPGG---KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEK 167
EES Q G K A + K+ D+ +E E+++ P PE Q + + K
Sbjct: 11 EESDASQEGDDLPKSSANTSHPKQDDSPKSSE-ETIQPKEGDIPKAPEETIQSKKEDLPK 69
Query: 168 DSLRAVEVTENPQTAAEMKPL-GTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENE 226
S +A++ E+ + KP+ N+ + +G + K + ETI + E
Sbjct: 70 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPE----ETIQSKKE 125
Query: 227 SPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKP 280
++ + S+ +E + + K QP+ L I K +V P S + + P
Sbjct: 126 --DLPKSSEEAIQPKEGDIPKSSAKPIQPK-LGNIAKTSVKPSQPKESDIPKSP 176
>gi|148727319 thioredoxin domain-containing 2 isoform 2 [Homo
sapiens]
Length = 553
Score = 42.4 bits (98), Expect = 7e-04
Identities = 80/362 (22%), Positives = 138/362 (38%), Gaps = 36/362 (9%)
Query: 10 KAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSA 69
K GD + P T +S QPK + N+ + S P+Q K+
Sbjct: 115 KEGDIPKAPEETIQSKKEDLPKSSEKAIQPK----------ESNIPKSSAKPIQP-KLGN 163
Query: 70 EPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEG 129
P A+ VKP QP D+ + T QS +K + EE+ P+ G D P +
Sbjct: 164 IPKAS-VKP--SQPKEGDIPKAPEETIQS---KKEDLPKSSEEAIQPKEG---DIPKSSA 214
Query: 130 KKKDAGAGTEAE-SLKGNAEAQ---PLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEM 185
K G A+ S+K + + P PE QP + + K S + ++ A +
Sbjct: 215 KPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASV 274
Query: 186 KPLGTTENVLTLQIAGELQP-QGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQ 244
KP E ++ +QP +G + K + + +SPE E Q E +
Sbjct: 275 KPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPE--EAIQPKEGDIPKS 332
Query: 245 LQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGI 304
L+ + +E + + P+E + P+ D + E+ + P+ P Q + I
Sbjct: 333 LEEAIQPKEGD--IPKSPEETIQPKKGDIPKSPEEAIQPKE-GDIPKSPKQAIQPKEGDI 389
Query: 305 VGSMEHPARNVEAGAYVEMIRSIHTNEED------QRIEGETGEKVETDMENEKVSEGAE 358
S+E E +I E+D + + G+ ++ + E + EG +
Sbjct: 390 PKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDK 449
Query: 359 TK 360
K
Sbjct: 450 VK 451
Score = 31.2 bits (69), Expect = 1.6
Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 12/174 (6%)
Query: 111 EESGPPQPGG---KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEK 167
EES Q G K A + K+ D+ +E E+++ P PE Q + + K
Sbjct: 78 EESDASQEGDDLPKSSANTSHPKQDDSPKSSE-ETIQPKEGDIPKAPEETIQSKKEDLPK 136
Query: 168 DSLRAVEVTENPQTAAEMKPL-GTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENE 226
S +A++ E+ + KP+ N+ + +G + K + ETI + E
Sbjct: 137 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPE----ETIQSKKE 192
Query: 227 SPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKP 280
++ + S+ +E + + K QP+ L I K +V P S + + P
Sbjct: 193 --DLPKSSEEAIQPKEGDIPKSSAKPIQPK-LGNIAKTSVKPSQPKESDIPKSP 243
>gi|42516570 thioredoxin domain-containing 2 isoform 1 [Homo
sapiens]
Length = 486
Score = 42.4 bits (98), Expect = 7e-04
Identities = 80/362 (22%), Positives = 138/362 (38%), Gaps = 36/362 (9%)
Query: 10 KAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQKLKVSA 69
K GD + P T +S QPK + N+ + S P+Q K+
Sbjct: 48 KEGDIPKAPEETIQSKKEDLPKSSEKAIQPK----------ESNIPKSSAKPIQP-KLGN 96
Query: 70 EPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKEDAPAAEG 129
P A+ VKP QP D+ + T QS +K + EE+ P+ G D P +
Sbjct: 97 IPKAS-VKP--SQPKEGDIPKAPEETIQS---KKEDLPKSSEEAIQPKEG---DIPKSSA 147
Query: 130 KKKDAGAGTEAE-SLKGNAEAQ---PLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEM 185
K G A+ S+K + + P PE QP + + K S + ++ A +
Sbjct: 148 KPIQPKLGNIAKTSVKPSQPKESDIPKSPEETIQPKEGDIPKSSAKPIQPKLGNIPKASV 207
Query: 186 KPLGTTENVLTLQIAGELQP-QGTVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQ 244
KP E ++ +QP +G + K + + +SPE E Q E +
Sbjct: 208 KPSQPKEGDISKSPEEAIQPKEGDLPKSLEEAIQPKEGDIPKSPE--EAIQPKEGDIPKS 265
Query: 245 LQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGI 304
L+ + +E + + P+E + P+ D + E+ + P+ P Q + I
Sbjct: 266 LEEAIQPKEGD--IPKSPEETIQPKKGDIPKSPEEAIQPKE-GDIPKSPKQAIQPKEGDI 322
Query: 305 VGSMEHPARNVEAGAYVEMIRSIHTNEED------QRIEGETGEKVETDMENEKVSEGAE 358
S+E E +I E+D + + G+ ++ + E + EG +
Sbjct: 323 PKSLEEAIPPKEIDIPKSPEETIQPKEDDSPKSLEEATPSKEGDILKPEEETMEFPEGDK 382
Query: 359 TK 360
K
Sbjct: 383 VK 384
Score = 31.2 bits (69), Expect = 1.6
Identities = 40/174 (22%), Positives = 72/174 (41%), Gaps = 12/174 (6%)
Query: 111 EESGPPQPGG---KEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEK 167
EES Q G K A + K+ D+ +E E+++ P PE Q + + K
Sbjct: 11 EESDASQEGDDLPKSSANTSHPKQDDSPKSSE-ETIQPKEGDIPKAPEETIQSKKEDLPK 69
Query: 168 DSLRAVEVTENPQTAAEMKPL-GTTENVLTLQIAGELQPQGTVGKDEQAPLLETISKENE 226
S +A++ E+ + KP+ N+ + +G + K + ETI + E
Sbjct: 70 SSEKAIQPKESNIPKSSAKPIQPKLGNIPKASVKPSQPKEGDIPKAPE----ETIQSKKE 125
Query: 227 SPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQLVEKP 280
++ + S+ +E + + K QP+ L I K +V P S + + P
Sbjct: 126 --DLPKSSEEAIQPKEGDIPKSSAKPIQPK-LGNIAKTSVKPSQPKESDIPKSP 176
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 42.0 bits (97), Expect = 9e-04
Identities = 79/342 (23%), Positives = 131/342 (38%), Gaps = 38/342 (11%)
Query: 59 RPPL-QKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEG-----LEE 112
+PPL ++ AEP +Q QP ++ AT + ++ K QP +E
Sbjct: 270 QPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEF 329
Query: 113 SGPPQPGGKEDAPAAE--------GKKKDAGAGTEAESLKGNAEAQP----LGPEAKGQP 160
QP E++P+ E ++ AE L AE P LG
Sbjct: 330 PAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSA 389
Query: 161 LQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQ-IAGELQPQGTVGKDEQAPLLE 219
+A +E L A E + A+++P E + +Q + E P+ + + + +E
Sbjct: 390 QKAPIEVQPLPAEGALE--EAPAKVEPPTVEETLADVQPLLPEEAPREEARELQLSTAME 447
Query: 220 TISKEN----ESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDRSQ 275
T ++E +SP E + +AE Q L AT E P + P E +P + S
Sbjct: 448 TPAEEAPTEFQSPLPKETTAEEASAEIQLLAAT----EPP--ADETPAEARSPLSEETSA 501
Query: 276 LVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEEDQR 335
+ P + +IQ ++ ++E PA A A + E
Sbjct: 502 EEAHAEVQSPLAEETTAEEASAEIQ---LLAAIEAPADETPAEAQSPLSEETSAEEAPAE 558
Query: 336 IEGETGEKV---ETDMENEKVSEGAETKEEETGEVVDLSAAT 374
++ + + V E +E + S G ET EE + L AAT
Sbjct: 559 VQSPSAKGVSIEEAPLELQPPS-GEETTAEEASAAIQLLAAT 599
Score = 34.3 bits (77), Expect = 0.19
Identities = 64/280 (22%), Positives = 102/280 (36%), Gaps = 44/280 (15%)
Query: 57 ESRPPLQKLKVSAEPTANGVKPLQEQPLAKDV-----------APGRD--ATDQSGSTEK 103
E+R PL + + E A PL E+ A++ AP + A QS +E+
Sbjct: 490 EARSPLSEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEE 549
Query: 104 TQPGEGLEESGPPQPGGK--EDAP-------AAEGKKKDAGAG------TEAESLKGNAE 148
T E E P G E+AP E ++A A TEA + + AE
Sbjct: 550 TSAEEAPAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAE 609
Query: 149 AQPLGPEAKGQPLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGT 208
QP E +Q +++ V+ + AE++P E E+QP
Sbjct: 610 VQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEE------APAEVQPPPA 663
Query: 209 VGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLG--KEEQPQLLERIPKENV 266
E+AP E+P ++ ET E+ L A ++ P + K +
Sbjct: 664 ----EEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSP 719
Query: 267 TPEVLDRSQL----VEKPVMNDPFHKTPEGPGNMEQIQPE 302
++L + V P +TPE +E + E
Sbjct: 720 PADLLLTEEFPIGEASAEVSPPPSEQTPEDEALVENVSTE 759
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 42.0 bits (97), Expect = 9e-04
Identities = 36/119 (30%), Positives = 51/119 (42%), Gaps = 8/119 (6%)
Query: 47 ESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQ---SGSTEK 103
ES ++G + PPL + + PTA PL + A G + S S++
Sbjct: 1220 ESELEGQPTPPAPPPLPE---TWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDW 1276
Query: 104 TQPGEGLEESG-PPQPGGKEDAPA-AEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQP 160
PG+GLE G PP P APA A G ++ +G A EA G + K +P
Sbjct: 1277 RVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRP 1335
>gi|23503317 coiled-coil domain containing 96 [Homo sapiens]
Length = 555
Score = 42.0 bits (97), Expect = 9e-04
Identities = 50/217 (23%), Positives = 85/217 (39%), Gaps = 15/217 (6%)
Query: 54 VQRESRPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEES 113
++ S PP S EP +P +E+ G A +Q+ + + E E
Sbjct: 28 IKASSGPP-----TSPEPGELESEPEEEEEEQAASQGGTAADEQAEAPKGLTAAEAAGEE 82
Query: 114 GPPQPGG------KEDAPAAEGKKKDA----GAGTEAESLKGNAEAQPLGPEAKGQPLQA 163
GP +PG + + PA G ++ A GAG E + AE E K QA
Sbjct: 83 GPGEPGRPAEPQPEPEEPAEVGAEEPAQPEPGAGPEELEAEAGAEELEQAAEGKEVRFQA 142
Query: 164 AVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAPLLETISK 223
++ + E P+ E + T + E + + G+ ++
Sbjct: 143 SLPLTRIDEEEAAAAPEAETERVEGEEEDKEETQRDGAESKERDGEGRPAKSQEEGKRLY 202
Query: 224 ENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLER 260
+ E LE S+ V+ +EQQL++ L + + L+ER
Sbjct: 203 GRDEFEDLEWSEEVQKLQEQQLRSDLLDQYRSLLVER 239
>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
sapiens]
Length = 1393
Score = 41.6 bits (96), Expect = 0.001
Identities = 86/390 (22%), Positives = 123/390 (31%), Gaps = 46/390 (11%)
Query: 4 SSSALNKAGDSSRFPSVTSNEHFSTAEESESCFAQPKPHALGRESTVDGNVQRESRPPLQ 63
+SS + R P S+AE +E P + S + RE +
Sbjct: 673 TSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEK 732
Query: 64 KLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQPGGKED 123
AEPT N + E P + + EKT P P GK
Sbjct: 733 TTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTP-----SLAEPTENGKRT 787
Query: 124 APAAEGKKKDAGAGTEAESLKGNAEAQPLGPE----AKGQPLQ----AAVEKDSLRAVEV 175
A E + TE +AE PL E + +P + A EK + E
Sbjct: 788 PFANEKTTSSSAEPTE------HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEP 841
Query: 176 TENPQTAAEMK----PLGTTEN-VLTLQIAGELQPQGTVGKDEQAPLLE----------- 219
TEN ++ A K P TEN T L P +E PL
Sbjct: 842 TENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPT 901
Query: 220 ------TISKENESPEILEGSQFVETAEEQQLQATLGKEEQPQLLERIPKENVTPEVLDR 273
+ E +P E ++ E T + E + ERI E TP
Sbjct: 902 ENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKATPSPAKP 961
Query: 274 SQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPARNVEAGAYVEMIRSIHTNEED 333
++ E V D + E N E+ P + P + E G ++ + E
Sbjct: 962 TEHGETTVNEDTTPSSAEPTENGER-TPLANENTTTSPTESTEHGERTANEKTTPSPAEP 1020
Query: 334 QRIEGETGEKVETDMENEKVSEGAETKEEE 363
E GE+ + E S T+ EE
Sbjct: 1021 T----EHGERTPSANEKTIPSPAKPTEHEE 1046
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 399 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 454
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 455 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 568
Score = 31.6 bits (70), Expect = 1.2
Identities = 45/200 (22%), Positives = 69/200 (34%), Gaps = 37/200 (18%)
Query: 108 EGLEESGPPQPGGKEDAPAAE-GKKKDAGAGTEAESLKGNAEA----------------- 149
E + P P GK AA+ GK+ D+G+ +E G A A
Sbjct: 828 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 887
Query: 150 --QPLGPEAKGQPLQAAVEKDSLRAVEVT----------ENPQTAAEMKPLGTTENVLTL 197
P GP A QAA RA E T E+ A + G NV+T+
Sbjct: 888 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 947
Query: 198 -----QIAGELQPQGTVGKDEQAPLLETISKENESPEILE--GSQFVETAEEQQLQATLG 250
+IA + G E + + + +E + ++ + + T ++ A
Sbjct: 948 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKA 1007
Query: 251 KEEQPQLLERIPKENVTPEV 270
E QP + P V V
Sbjct: 1008 SEAQPPVARTQPSSGVDSAV 1027
>gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e
[Homo sapiens]
Length = 1451
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 531
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 532 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
Score = 31.6 bits (70), Expect = 1.2
Identities = 45/205 (21%), Positives = 73/205 (35%), Gaps = 37/205 (18%)
Query: 108 EGLEESGPPQPGGKEDAPAAE-GKKKDAGAGTEAESLKGNAEA----------------- 149
E + P P GK AA+ GK+ D+G+ +E G A A
Sbjct: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
Query: 150 --QPLGPEAKGQPLQAAVEKDSLRAVEVT----------ENPQTAAEMKPLGTTENVLTL 197
P GP A QAA RA E T E+ A + G NV+T+
Sbjct: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
Query: 198 -----QIAGELQPQGTVGKDEQAPLLETISKENESPEI--LEGSQFVETAEEQQLQATLG 250
+IA + G E + + + +E + ++ G+ + + +QA
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGT 1084
Query: 251 KEEQPQLLERIPKENVTPEVLDRSQ 275
+ + L + + PE D S+
Sbjct: 1085 NKLRKPKLPEVQQATKAPESSDDSE 1109
>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
[Homo sapiens]
Length = 1488
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 531
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 532 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
Score = 31.6 bits (70), Expect = 1.2
Identities = 45/200 (22%), Positives = 69/200 (34%), Gaps = 37/200 (18%)
Query: 108 EGLEESGPPQPGGKEDAPAAE-GKKKDAGAGTEAESLKGNAEA----------------- 149
E + P P GK AA+ GK+ D+G+ +E G A A
Sbjct: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
Query: 150 --QPLGPEAKGQPLQAAVEKDSLRAVEVT----------ENPQTAAEMKPLGTTENVLTL 197
P GP A QAA RA E T E+ A + G NV+T+
Sbjct: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
Query: 198 -----QIAGELQPQGTVGKDEQAPLLETISKENESPEILE--GSQFVETAEEQQLQATLG 250
+IA + G E + + + +E + ++ + + T ++ A
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKA 1084
Query: 251 KEEQPQLLERIPKENVTPEV 270
E QP + P V V
Sbjct: 1085 SEAQPPVARTQPSSGVDSAV 1104
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 399 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 454
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 455 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 511
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 512 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 568
Score = 31.6 bits (70), Expect = 1.2
Identities = 45/200 (22%), Positives = 69/200 (34%), Gaps = 37/200 (18%)
Query: 108 EGLEESGPPQPGGKEDAPAAE-GKKKDAGAGTEAESLKGNAEA----------------- 149
E + P P GK AA+ GK+ D+G+ +E G A A
Sbjct: 828 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 887
Query: 150 --QPLGPEAKGQPLQAAVEKDSLRAVEVT----------ENPQTAAEMKPLGTTENVLTL 197
P GP A QAA RA E T E+ A + G NV+T+
Sbjct: 888 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 947
Query: 198 -----QIAGELQPQGTVGKDEQAPLLETISKENESPEILE--GSQFVETAEEQQLQATLG 250
+IA + G E + + + +E + ++ + + T ++ A
Sbjct: 948 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKA 1007
Query: 251 KEEQPQLLERIPKENVTPEV 270
E QP + P V V
Sbjct: 1008 SEAQPPVARTQPSSGVDSAV 1027
>gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a
[Homo sapiens]
Length = 1450
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 531
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 532 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
Score = 31.6 bits (70), Expect = 1.2
Identities = 45/205 (21%), Positives = 73/205 (35%), Gaps = 37/205 (18%)
Query: 108 EGLEESGPPQPGGKEDAPAAE-GKKKDAGAGTEAESLKGNAEA----------------- 149
E + P P GK AA+ GK+ D+G+ +E G A A
Sbjct: 905 ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDP 964
Query: 150 --QPLGPEAKGQPLQAAVEKDSLRAVEVT----------ENPQTAAEMKPLGTTENVLTL 197
P GP A QAA RA E T E+ A + G NV+T+
Sbjct: 965 NRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTM 1024
Query: 198 -----QIAGELQPQGTVGKDEQAPLLETISKENESPEI--LEGSQFVETAEEQQLQATLG 250
+IA + G E + + + +E + ++ G+ + + +QA
Sbjct: 1025 PTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVDSAVGTLPATSPQSTSVQAKGT 1084
Query: 251 KEEQPQLLERIPKENVTPEVLDRSQ 275
+ + L + + PE D S+
Sbjct: 1085 NKLRKPKLPEVQQATKAPESSDDSE 1109
>gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c
[Homo sapiens]
Length = 958
Score = 41.2 bits (95), Expect = 0.002
Identities = 39/177 (22%), Positives = 75/177 (42%), Gaps = 13/177 (7%)
Query: 46 RESTVDGNVQRESRPPLQKLKVSAEPTANGVKPLQEQ---PLAKD---VAPGRDATDQSG 99
R S+ + + RE+ + +V + VKP PL K V PG+
Sbjct: 476 RSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---- 531
Query: 100 STEKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ 159
+T Q G+ E+S + +E + +++G+ A A + +SL +A+P AKG
Sbjct: 532 ATPSAQVGKWEEDS---ESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588
Query: 160 PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTTENVLTLQIAGELQPQGTVGKDEQAP 216
P +A ++A + +N +++ E +E A + +P + + + P
Sbjct: 589 PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACP 645
>gi|118498345 AT-binding transcription factor 1 [Homo sapiens]
Length = 3703
Score = 41.2 bits (95), Expect = 0.002
Identities = 65/275 (23%), Positives = 107/275 (38%), Gaps = 31/275 (11%)
Query: 1 MGCSSSALNKAG-DSSRFPSVTSNEHFSTAEESESCFAQ-PKPHALGRESTVDGNVQRES 58
MG S+ + G +S P+ S+ S+ +++ A P+ ++ VQ+
Sbjct: 3152 MGLPSTTVPSPGLPTSGLPNKPSSASLSSPTPAQATMAMGPQQPPQQQQQQQQPQVQQPP 3211
Query: 59 RPPLQKLKVSAEPTANGVKPLQEQPLAKDVAPGRDATDQSGSTEKTQPGEGLEESGPPQP 118
PP +A+P PLQ+Q KD D EK + +G E P
Sbjct: 3212 PPP------AAQPPPTPQLPLQQQQQRKD-------KDSEKVKEKEKAHKGKGEPLPVPK 3258
Query: 119 GGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQPLQAAVEKDSLRAVEVTEN 178
K +AP A A T ++ A+ Q LQAA+ D +
Sbjct: 3259 KEKGEAPTATAATISAPLPTMEYAVD----------PAQLQALQAALTSDPTALLTSQFL 3308
Query: 179 PQTAAEMKPLGTTENVLTLQIAGELQPQ-GTVGKDEQAPLLET----ISKENESPEILEG 233
P P + LQ +G LQP G G +P L +S + + +
Sbjct: 3309 PYFVPGFSPYYAPQIPGALQ-SGYLQPMYGMEGLFPYSPALSQALMGLSPGSLLQQYQQY 3367
Query: 234 SQFVETAEEQQLQATLGKEEQPQLLERIPKENVTP 268
Q ++ A +QQ Q L +++Q ++ ++ PK + TP
Sbjct: 3368 QQSLQEAIQQQQQRQLQQQQQQKVQQQQPKASQTP 3402
>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
Length = 696
Score = 41.2 bits (95), Expect = 0.002
Identities = 63/302 (20%), Positives = 119/302 (39%), Gaps = 44/302 (14%)
Query: 102 EKTQPGEGLEESGPPQPGGKEDAPAAEGKKKDAGAGTEAESLKGNAEAQPLGPEAKGQ-- 159
E+ E LEE P P ++ + ++++A A L+G+A A+ + P AK
Sbjct: 349 EQVGQAEHLEEEHDPSPEEQDREWKEQHEQREA-----ANLLEGHARAE-VYPSAKPMIK 402
Query: 160 ---PLQAAVEKDSLRAVEVTENPQTAAEMKPLGTT---------ENVLTLQIAGELQPQG 207
P + +E+ L +V E Q + L + Q+A E+ Q
Sbjct: 403 FQSPYEEQLEQQRLAVQQVEEAQQLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQR 462
Query: 208 TVGKDEQAPLLETISKENESPEILEGSQFVETAEEQQLQATLGKEEQP------------ 255
+E P + ++ + ++ + V+ AE+Q +Q G E+
Sbjct: 463 QAELEEGRPQHQEQLRQQAHYDAMD-NDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPG 521
Query: 256 ---QLLERIPKENVTPEVLDRSQLVEKPVMNDPFHKTPEGPGNMEQIQPEGIVGSMEHPA 312
+ E+ P+E DR+ + + +DP ++ + EQ++ E + E
Sbjct: 522 NRHEPREQGPREADPESEADRAAVEDINPADDPNNQGEDEFEEAEQVREENLPDENEEQK 581
Query: 313 R------NVEAGAYVEMIRSIHTNEE--DQRIEGETGEKVETDMENEKVSEGAETKEEET 364
+ N E ++ M + E+ D++ + E E+V+ D+ EK E EE
Sbjct: 582 QSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQEDLTEEKKRELEHNAEETY 641
Query: 365 GE 366
GE
Sbjct: 642 GE 643
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.301 0.123 0.330
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,372,054
Number of Sequences: 37866
Number of extensions: 907904
Number of successful extensions: 4843
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 71
Number of HSP's successfully gapped in prelim test: 394
Number of HSP's that attempted gapping in prelim test: 3956
Number of HSP's gapped (non-prelim): 1127
length of query: 374
length of database: 18,247,518
effective HSP length: 104
effective length of query: 270
effective length of database: 14,309,454
effective search space: 3863552580
effective search space used: 3863552580
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.