Search of human proteins with 27477127

Search of human proteins with 27477127

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|27477127 keratin 82 [Homo sapiens]
         (513 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|27477127 keratin 82 [Homo sapiens]                                1030   0.0  
gi|4504935 keratin 85 [Homo sapiens]                                  566   e-161
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    546   e-155
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   533   e-151
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   533   e-151
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   533   e-151
gi|14318422 keratin 86 [Homo sapiens]                                 533   e-151
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   531   e-151
gi|169790841 keratin 83 [Homo sapiens]                                522   e-148
gi|119395754 keratin 5 [Homo sapiens]                                 453   e-127
gi|5031839 keratin 6A [Homo sapiens]                                  452   e-127
gi|153791158 keratin 75 [Homo sapiens]                                451   e-127
gi|155969697 keratin 6C [Homo sapiens]                                447   e-125
gi|119703753 keratin 6B [Homo sapiens]                                446   e-125
gi|67782365 keratin 7 [Homo sapiens]                                  428   e-120
gi|4504919 keratin 8 [Homo sapiens]                                   419   e-117
gi|28173564 keratin 73 [Homo sapiens]                                 416   e-116
gi|15618995 keratin 71 [Homo sapiens]                                 415   e-116
gi|32567786 keratin 6L [Homo sapiens]                                 410   e-114
gi|109148552 keratin 3 [Homo sapiens]                                 410   e-114
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       407   e-114
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      407   e-114
gi|119395750 keratin 1 [Homo sapiens]                                 407   e-113
gi|148612803 keratin 6 irs4 [Homo sapiens]                            404   e-112
gi|109255249 keratin 4 [Homo sapiens]                                 400   e-111
gi|153791670 keratin 76 [Homo sapiens]                                396   e-110
gi|47132620 keratin 2 [Homo sapiens]                                  389   e-108
gi|194018511 keratin 77 [Homo sapiens]                                372   e-103
gi|89357932 keratin 5b [Homo sapiens]                                 354   9e-98
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      345   4e-95

>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score = 1030 bits (2662), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV 60
           MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV
Sbjct: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV 60

Query: 61  GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120
           GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE
Sbjct: 61  GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120

Query: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQL 180
           KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQL
Sbjct: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQL 180

Query: 181 DCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLE 240
           DCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLE
Sbjct: 181 DCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLE 240

Query: 241 TNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIA 300
           TNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIA
Sbjct: 241 TNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIA 300

Query: 301 SRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKL 360
           SRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKL
Sbjct: 301 SRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKL 360

Query: 361 EGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATY 420
           EGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATY
Sbjct: 361 EGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATY 420

Query: 421 RRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGEL 480
           RRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGEL
Sbjct: 421 RRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGEL 480

Query: 481 YVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHKH 513
           YVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHKH
Sbjct: 481 YVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHKH 513


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  566 bits (1459), Expect = e-161
 Identities = 307/505 (60%), Positives = 368/505 (72%), Gaps = 12/505 (2%)

Query: 1   MSYHSFQPGSRCG-SQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCN 59
           MS  S++  S CG +++FSS SAV P+      +S  P R  G    R L   GSRSLCN
Sbjct: 1   MSCRSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYR--GVSCYRGLTGFGSRSLCN 58

Query: 60  VGFGRPRVAS---RCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQR 115
           +G   PR+A    R G     FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q 
Sbjct: 59  LGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 118

Query: 116 VKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISA 175
           VK++EKEQIK LN+RFA+FI+KVRFLEQ+NKLLETKW F Q QRCC++N+EP+F GYI  
Sbjct: 119 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLEPLFSGYIET 178

Query: 176 LRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLM 235
           LRR+ +CV  D  RL SEL  +Q  LEGYKKKYEEE++LR   ENEFV LKKDVD A+L 
Sbjct: 179 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLR 238

Query: 236 KADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQ 295
           K+DLE N EALV+E  FL+ LYEEEI +LQ+ IS+TSVIVKMDNSR+L++D IIAEIKAQ
Sbjct: 239 KSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQ 298

Query: 296 YDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKA 355
           YDD+ASRS+AEAE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K 
Sbjct: 299 YDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKC 358

Query: 356 QRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDI 415
           QR KLE A+AEAEQQGEAAL+DA+CKLA LE ALQKAKQDMACLLKEYQEVMNSKLGLDI
Sbjct: 359 QRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDI 418

Query: 416 EIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTP---VLSTGVLRSNGGC 472
           EIATYRRLLEGEEHRLCEG+G VN+ VSSS+G         ST     +++G     G  
Sbjct: 419 EIATYRRLLEGEEHRLCEGVGSVNVCVSSSRGGVSCGGLSYSTTPGRQITSGPSAIGGSI 478

Query: 473 SIVGTGELYVPCEPQ-GLLSCGSGR 496
           ++V   +   PC+P+    SCGS R
Sbjct: 479 TVVAP-DSCAPCQPRSSSFSCGSSR 502


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  546 bits (1408), Expect = e-155
 Identities = 306/552 (55%), Positives = 376/552 (68%), Gaps = 60/552 (10%)

Query: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV 60
           MS  S++  S     +FSS SA+ P+ +  +  +   C    G G R LG  GSRS+   
Sbjct: 1   MSCRSYRVSSGHRVGNFSSCSAMTPQNLNRFRANSVSC--WSGPGFRGLGSFGSRSVITF 58

Query: 61  GFGRPRVAS------RCGGTL--------------------------------------- 75
           G   PR+A+       CG                                          
Sbjct: 59  GSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFG 118

Query: 76  -PGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFAS 133
            PGFGYR+G    P+A  IT VT+N+SLL PL LEIDP  QRVK+DEKEQIK LNN+FAS
Sbjct: 119 GPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFAS 178

Query: 134 FINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESE 193
           FI+KVRFLEQ+NKLLETKW+F+Q+Q+C ++N+EP+FE YI+ LRRQL+ +  D+ RL++E
Sbjct: 179 FIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLEPLFESYITNLRRQLEVLVSDQARLQAE 238

Query: 194 LCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFL 253
              LQ  LEG+KKKYEEE+  R   ENEFVALKKDVD AF+ K+DLE N + L QEIDFL
Sbjct: 239 RNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFL 298

Query: 254 KSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQC 313
           K+LY EEI LLQS ISETSVIVKMDNSR+L++DGIIAE+KAQY+++A RS+A+AEAWYQ 
Sbjct: 299 KTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQT 358

Query: 314 RYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEA 373
           +YEE++VTAG HCDNLRN +NEI E+ +LIQRL+ E E+ KAQR KLE A+AEAEQQGEA
Sbjct: 359 KYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEA 418

Query: 374 ALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCE 433
            L+DAKCKLA LE ALQ+AKQDMA  L EYQE+MN+KLGLDIEIATYRRLLEGEE RLCE
Sbjct: 419 TLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCE 478

Query: 434 GIGPVNISVSSSKGAFLYEPCG----VSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGL 489
           G+GPVNISVSSS+G  +   CG    V+   LS G +  +G  S+  T  +   C P   
Sbjct: 479 GVGPVNISVSSSRGGLV---CGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGP--- 532

Query: 490 LSCGSGRKSSMT 501
            S G  R +  T
Sbjct: 533 -SLGGARVAPAT 543


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  533 bits (1373), Expect = e-151
 Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
           GS CG ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 4   GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55

Query: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112

Query: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172

Query: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232

Query: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292

Query: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352

Query: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412

Query: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482
           EE RLCEG+G VN+ VSSS+G  +      ST  PV+ST V  + SN    +VGT     
Sbjct: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471

Query: 483 PCEPQGLLSCGSGRK 497
           P    G+  CG   K
Sbjct: 472 PSARVGV--CGGSCK 484


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  533 bits (1373), Expect = e-151
 Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
           GS CG ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 4   GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55

Query: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112

Query: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172

Query: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232

Query: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292

Query: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352

Query: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412

Query: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482
           EE RLCEG+G VN+ VSSS+G  +      ST  PV+ST V  + SN    +VGT     
Sbjct: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471

Query: 483 PCEPQGLLSCGSGRK 497
           P    G+  CG   K
Sbjct: 472 PSARVGV--CGGSCK 484


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  533 bits (1373), Expect = e-151
 Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
           GS CG ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 4   GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55

Query: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112

Query: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172

Query: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232

Query: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292

Query: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352

Query: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412

Query: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482
           EE RLCEG+G VN+ VSSS+G  +      ST  PV+ST V  + SN    +VGT     
Sbjct: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471

Query: 483 PCEPQGLLSCGSGRK 497
           P    G+  CG   K
Sbjct: 472 PSARVGV--CGGSCK 484


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  533 bits (1373), Expect = e-151
 Identities = 299/495 (60%), Positives = 358/495 (72%), Gaps = 20/495 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
           GS CG ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 4   GSYCGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55

Query: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112

Query: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172

Query: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232

Query: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 233 IQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292

Query: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352

Query: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412

Query: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVST--PVLSTGV--LRSNGGCSIVGTGELYV 482
           EE RLCEG+G VN+ VSSS+G  +      ST  PV+ST V  + SN    +VGT     
Sbjct: 413 EEQRLCEGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNSNV-VVGTTNACA 471

Query: 483 PCEPQGLLSCGSGRK 497
           P    G+  CG   K
Sbjct: 472 PSARVGV--CGGSCK 484


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  531 bits (1368), Expect = e-151
 Identities = 302/514 (58%), Positives = 359/514 (69%), Gaps = 28/514 (5%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGRPRV 67
           GS  G ++FS  SA  PR      ++  P R     RGL   G  GS S+C  GF     
Sbjct: 4   GSGFGGRAFSCISACGPRP-GRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR---- 55

Query: 68  ASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKC 126
           A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQIK 
Sbjct: 56  AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKS 112

Query: 127 LNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCVSGD 186
           LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+FEGYI  LRR+ +CV  D
Sbjct: 113 LNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFEGYIETLRREAECVEAD 172

Query: 187 RVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEAL 246
             RL SEL  +Q  LEGYKKKYEEE+SLR   ENEFVALKKDVD A+L K+DLE N EAL
Sbjct: 173 SGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEAL 232

Query: 247 VQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAE 306
           +QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D IIAEIKAQYDDI +RS+AE
Sbjct: 233 IQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAE 292

Query: 307 AEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAE 366
           AE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A+A+
Sbjct: 293 AESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQ 352

Query: 367 AEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEG 426
           +EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRLLEG
Sbjct: 353 SEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEG 412

Query: 427 EEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP--- 483
           EE RLCEGIG VN+ VSSS+G  +     VS     TG +     CS    G + V    
Sbjct: 413 EEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNVAVSTGL 467

Query: 484 CEPQGLL-------SCGSGRKSSMTLGAGGSSPS 510
           C P G L       SCG G     +LG G    S
Sbjct: 468 CAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSS 501


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  522 bits (1345), Expect = e-148
 Identities = 296/503 (58%), Positives = 356/503 (70%), Gaps = 34/503 (6%)

Query: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRP-GGGRGLRALGCLGSRSLCNVGFGR 64
           F+PG+      FS  SA  PR  +   ++  P R     RGL   G  GS S+C  GF  
Sbjct: 12  FRPGN------FSCVSACGPRP-SRCCITAAPYRGISCYRGLT--GGFGSHSVCG-GFR- 60

Query: 65  PRVASRCGGTLPGFGYRLGATCGPSA-CITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123
              A  CG +   FGYR G  CGPS  CIT V++NESLL PL LEIDP  Q VK++EKEQ
Sbjct: 61  ---AGSCGRS---FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQ 114

Query: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGYISALRRQLDCV 183
           IK LN+RFA+FI+KVRFLEQ+NKLLETK  F Q + CCQ+N+EP+F GYI  LRR+ +CV
Sbjct: 115 IKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEPLFAGYIETLRREAECV 174

Query: 184 SGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNA 243
             D  RL SEL  +Q  LEGYKKKYEEE++LR   ENEFVALKKDVD A+L K+DLE N 
Sbjct: 175 EADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANV 234

Query: 244 EALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRS 303
           EAL+QEIDFL+ LYEEEI +LQS IS+TSV+VK+DNSR+L++D I+AEIKAQYDDIA+RS
Sbjct: 235 EALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRS 294

Query: 304 KAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGA 363
           +AEAE+WY+ + EE++ T   H + LR  K EI E+N++IQRL  E EN K Q  KLE A
Sbjct: 295 RAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAA 354

Query: 364 IAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRL 423
           +A++EQQGEAAL+DA+CKLA LE ALQKAKQDMACL++EYQEVMNSKLGLDIEIATYRRL
Sbjct: 355 VAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRL 414

Query: 424 LEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVP 483
           LEGEE RLCEG+  VN+ VSSS+G  +     VS     TG +     CS    G L V 
Sbjct: 415 LEGEEQRLCEGVEAVNVCVSSSRGGVVCGDLCVSGSRPVTGSV-----CSAPCNGNLVVS 469

Query: 484 ---CEPQGLL-------SCGSGR 496
              C+P G L       SCG GR
Sbjct: 470 TGLCKPCGQLNTTCGGGSCGQGR 492


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  453 bits (1166), Expect = e-127
 Identities = 269/569 (47%), Positives = 361/569 (63%), Gaps = 66/569 (11%)

Query: 5   SFQPGSRCGSQSFSSYSAVMPRM--VTHYAVSKGPCRPGGGRGLRAL------GCLGSRS 56
           SF+ G   GS+SFS+ SA+ P +   +  +VS+     GGG G  +L      G  GSRS
Sbjct: 8   SFRSG---GSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRS 64

Query: 57  LCNVGFGRPRVASRCGGTL-------------------PGFGYRLGATCG---------- 87
           L N+G  +    S  GG+                     GFG+  GA  G          
Sbjct: 65  LYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFG 124

Query: 88  -----------PSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFIN 136
                      P   I  VT+N+SLL PL L+IDP++QRV+ +E+EQIK LNN+FASFI+
Sbjct: 125 GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFID 184

Query: 137 KVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESEL 194
           KVRFLEQ+NK+L+TKW  +Q+Q  +  + N+EP+FE YI+ LRRQLD + G+R RL+SEL
Sbjct: 185 KVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSEL 244

Query: 195 CSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLK 254
            ++Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K +LE   +AL+ EI+F+K
Sbjct: 245 RNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMK 304

Query: 255 SLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCR 314
             ++ E+  +Q+ +S+TSV++ MDN+R LD+D IIAE+KAQY++IA+RS+ EAE+WYQ +
Sbjct: 305 MFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTK 364

Query: 315 YEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAA 374
           YEEL+ TAG H D+LRN K+EI EMN++IQRL+ E +NVK Q   L+ AIA+AEQ+GE A
Sbjct: 365 YEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELA 424

Query: 375 LNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-E 433
           L DA+ KLA LEEALQKAKQDMA LL+EYQE+MN+KL LD+EIATYR+LLEGEE RL  E
Sbjct: 425 LKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGE 484

Query: 434 GIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGL---- 489
           G+GPVNISV +S  +  Y         L  G+    GG    G+   Y      G+    
Sbjct: 485 GVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGG 544

Query: 490 --------LSCGSGRKSSMTLGAGGSSPS 510
                    S  SGR   +  G+GG S S
Sbjct: 545 GLSVGGSGFSASSGRGLGVGFGSGGGSSS 573


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  452 bits (1162), Expect = e-127
 Identities = 262/523 (50%), Positives = 339/523 (64%), Gaps = 24/523 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSL---------CN 59
           G  CG   F S S          ++  G C   GG G RA G  G               
Sbjct: 48  GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAG 107

Query: 60  VGFGRPRVASRCGGTL-PGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKR 118
           +GFG    A   GG   PGF       C P   I  VT+N+SLL PL L+IDPT+QRV+ 
Sbjct: 108 IGFGLGGGAGLAGGFGGPGF-----PVCPPGG-IQEVTVNQSLLTPLNLQIDPTIQRVRA 161

Query: 119 DEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISAL 176
           +E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +Q+Q  +  + N+EP+FE YI+ L
Sbjct: 162 EEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNL 221

Query: 177 RRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMK 236
           RRQLD + G+R RL+SEL  +Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K
Sbjct: 222 RRQLDSIVGERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNK 281

Query: 237 ADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQY 296
            +L+  A+ L  EI+FL++LY+ E+  +Q+ IS+TSV++ MDN+R LD+D IIAE+KAQY
Sbjct: 282 VELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQY 341

Query: 297 DDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQ 356
           ++IA RS+AEAE+WYQ +YEEL+VTAG H D+LRN K EI E+N++IQRL+ E ++VK Q
Sbjct: 342 EEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQ 401

Query: 357 RCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIE 416
              L+ AIA+AEQ+GE AL DAK KL GLE+ALQKAKQD+A LLKEYQE+MN KL LD+E
Sbjct: 402 CANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVE 461

Query: 417 IATYRRLLEGEEHRL-CEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIV 475
           IATYR+LLEGEE RL  EG+G VNISV  S  +  Y         L  G   S    S +
Sbjct: 462 IATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGL 521

Query: 476 GTGELYVPCEPQ----GLLSCGSGRKS-SMTLGAGGSSPSHKH 513
           G G  +     +    GL S G G  +   T  +  S  S+KH
Sbjct: 522 GVGGGFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  451 bits (1161), Expect = e-127
 Identities = 268/540 (49%), Positives = 355/540 (65%), Gaps = 42/540 (7%)

Query: 5   SFQPGSRCGSQSFSSYSAVMPRM----VTHYAVSKGPCRPGG-GRGLRALGCLGSRSLCN 59
           +FQ GSR G   FS+ SA+ P       +  +V++     GG GR   A    GSRSL N
Sbjct: 8   TFQSGSRRG---FSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYN 64

Query: 60  VGFGRPRVASRCG---------------GTLPGFGYRLGAT---CGPSACITP------V 95
           +G  +    + CG               G   GFGY  G      GPS  + P      V
Sbjct: 65  LGGAKRVSINGCGSSCRSGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEV 124

Query: 96  TINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFM 155
           T+N+SLL PL L+IDPT+QRV+ +E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +
Sbjct: 125 TVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALL 184

Query: 156 QQQ--RCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELS 213
           Q+Q  R  + N+EP+F+ Y S LRRQL+ ++ +R RLE+EL ++Q  +E +K +YE+E++
Sbjct: 185 QEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEIN 244

Query: 214 LRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSV 273
            R   ENEFVALKKDVD A++ K +LE   ++L +EI+F+ S+++ E+  LQ+Q+ +TSV
Sbjct: 245 KRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSV 304

Query: 274 IVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRK 333
           ++ MDN+R LD+D IIAE+KAQY+DIA+RS+AEAE+WYQ +YEEL+VTAG H D+LRN K
Sbjct: 305 VLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTK 364

Query: 334 NEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAK 393
            EI EMN++IQRL+ E ++VK Q   L+ AIA+AEQ+GE AL DA+ KL  LEEALQKAK
Sbjct: 365 QEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAK 424

Query: 394 QDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYE 452
           QDMA LL+EYQE+MN KL LD+EIATYR+LLEGEE RL  EG+ PVNISV +S  +  Y 
Sbjct: 425 QDMARLLREYQELMNIKLALDVEIATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYG 484

Query: 453 PCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512
               S   +  G L   GG     T          G    GSG  ++   G GGS  S K
Sbjct: 485 ----SGSSIGGGNLGLGGGSGYSFTTS---GGHSLGAGLGGSGFSATSNRGLGGSGSSVK 537


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  447 bits (1150), Expect = e-125
 Identities = 259/519 (49%), Positives = 336/519 (64%), Gaps = 52/519 (10%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSL---------CN 59
           G  CG   F S S          ++  G C   GG G RA G  G               
Sbjct: 48  GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAG 107

Query: 60  VGFGRPRVASRCGGTL-PGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKR 118
           +GFG    A   GG   PGF       C P   I  VT+N+SLL PL L+IDP +QRV+ 
Sbjct: 108 IGFGLGGGAGLAGGFGGPGF-----PVCPPGG-IQEVTVNQSLLTPLNLQIDPAIQRVRA 161

Query: 119 DEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISAL 176
           +E+EQIK LNN+FASFI+KVRFLEQ+NK+L+TKW  +Q+Q  +  + N+EP+FE YI+ L
Sbjct: 162 EEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNL 221

Query: 177 RRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMK 236
           RRQLD + G+R RL+SEL ++Q  +E  K KYE+E++ R   ENEFV LKKDVD A++ K
Sbjct: 222 RRQLDSIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNK 281

Query: 237 ADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQY 296
            +L+  A+ L  EI+FL++LY+ E+  +Q+ IS+TSV++ MDN+R LD+D IIAE+KAQY
Sbjct: 282 VELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQY 341

Query: 297 DDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQ 356
           ++IA RS+AEAE+WYQ +YEEL+VTAG H D+LRN K EI E+N++IQRL+ E ++VK Q
Sbjct: 342 EEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQ 401

Query: 357 RCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIE 416
              L+ AIA+AEQ+GE AL DAK KL GLE+ALQKAKQD+A LLKEYQE+MN KL LD+E
Sbjct: 402 CASLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVE 461

Query: 417 IATYRRLLEGEEHRL-CEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIV 475
           IATYR+LLEGEE RL  EG+G VN+SV  S               +S+G     GG S V
Sbjct: 462 IATYRKLLEGEECRLNGEGVGQVNVSVVQS--------------TISSGY----GGASGV 503

Query: 476 GTGELYVPCEPQGLLSCGSGRK----SSMTLGAGGSSPS 510
           G+G           L  G G      S + +G G SS S
Sbjct: 504 GSG-----------LGLGGGSSYSYGSGLGIGGGFSSSS 531


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  446 bits (1148), Expect = e-125
 Identities = 259/523 (49%), Positives = 338/523 (64%), Gaps = 24/523 (4%)

Query: 9   GSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSL---------CN 59
           G  CG   F S S          ++  G C   GG G RA G  G               
Sbjct: 48  GGACGGAGFGSRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAG 107

Query: 60  VGFGRPRVASRCGGTL-PGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKR 118
           +GFG    A   GG   PGF       C P   I  VT+N+SLL PL L+IDP +QRV+ 
Sbjct: 108 IGFGLGGGAGLAGGFGGPGF-----PVCPPGG-IQEVTVNQSLLTPLNLQIDPAIQRVRA 161

Query: 119 DEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISAL 176
           +E+EQIK LNN+FASFI+KVRFLEQ+NK+L+TKW  +Q+Q  +  + N+EP+FE YI+ L
Sbjct: 162 EEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNL 221

Query: 177 RRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMK 236
           RRQLD + G+R RL+SEL ++Q  +E  K KYE+E++ R   ENEFV LKKDVD A++ K
Sbjct: 222 RRQLDNIVGERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNK 281

Query: 237 ADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQY 296
            +L+  A+ L  EI+FL++LY+ E+  +Q+ IS+TSV++ MDN+R LD+D IIAE+KAQY
Sbjct: 282 VELQAKADTLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQY 341

Query: 297 DDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQ 356
           ++IA RS+AEAE+WYQ +YEEL++TAG H D+LRN K EI E+N++IQRL+ E ++VK Q
Sbjct: 342 EEIAQRSRAEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQ 401

Query: 357 RCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIE 416
              L+ AIA+AEQ+GE AL DAK KL GLE+ALQKAKQD+A LLKEYQE+MN KL LD+E
Sbjct: 402 CANLQAAIADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVE 461

Query: 417 IATYRRLLEGEEHRL-CEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIV 475
           IATYR+LLEGEE RL  EG+G VNISV  S  +  Y         L  G   S    S +
Sbjct: 462 IATYRKLLEGEECRLNGEGVGQVNISVVQSTVSSGYGGASGVGSGLGLGGGSSYSYGSGL 521

Query: 476 GTGELYVPCEPQ----GLLSCGSGRKS-SMTLGAGGSSPSHKH 513
           G G  +     +    GL S G G  +   T  +  S  S+KH
Sbjct: 522 GVGGGFSSSSGRATGGGLSSVGGGSSTIKYTTTSSSSRKSYKH 564


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  428 bits (1101), Expect = e-120
 Identities = 243/449 (54%), Positives = 309/449 (68%), Gaps = 31/449 (6%)

Query: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV 60
           MS H   P     S +FS   A          V     RPGG         LGS SL  +
Sbjct: 1   MSIHFSSPVFTSRSAAFSGRGA---------QVRLSSARPGG---------LGSSSLYGL 42

Query: 61  GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120
           G  RPRVA R       +G  +GA       I  VTIN+SLL PL L+ DP++QRV+++E
Sbjct: 43  GASRPRVAVRSA-----YGGPVGAG------IREVTINQSLLAPLRLDADPSLQRVRQEE 91

Query: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEP-IFEGYISALRRQ 179
            EQIK LNN+FASFI+KVRFLEQ+NKLLETKW  +Q+Q+  +++  P IFE  I+ LR Q
Sbjct: 92  SEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQ 151

Query: 180 LDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADL 239
           L+ +  D  RLE+EL S+Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K +L
Sbjct: 152 LEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVEL 211

Query: 240 ETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDI 299
           E   +AL  EI+FL++L E E+  LQSQIS+TSV++ MDNSR LD+DGIIAE+KAQY+++
Sbjct: 212 EAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEM 271

Query: 300 ASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCK 359
           A  S+AEAEAWYQ ++E L+  AG H D+LRN +NEI EMN+ IQRLQ E +N+K QR K
Sbjct: 272 AKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAK 331

Query: 360 LEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIAT 419
           LE AIAEAE++GE AL DA+ K   LE ALQ+ KQDMA  L+EYQE+M+ KL LDIEIAT
Sbjct: 332 LEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIAT 391

Query: 420 YRRLLEGEEHRLC-EGIGPVNISVSSSKG 447
           YR+LLEGEE RL  +G+G VNISV +S G
Sbjct: 392 YRKLLEGEESRLAGDGVGAVNISVMNSTG 420


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  419 bits (1078), Expect = e-117
 Identities = 221/395 (55%), Positives = 293/395 (74%), Gaps = 6/395 (1%)

Query: 53  GSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPT 112
           GSR + +  F R   ++  GG   G+G   G        IT VT+N+SLL PL LE+DP 
Sbjct: 30  GSR-ISSSSFSRVGSSNFRGGLGGGYGGASGM-----GGITAVTVNQSLLSPLVLEVDPN 83

Query: 113 VQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEPIFEGY 172
           +Q V+  EKEQIK LNN+FASFI+KVRFLEQ+NK+LETKW+ +QQQ+  ++N++ +FE Y
Sbjct: 84  IQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESY 143

Query: 173 ISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTA 232
           I+ LRRQL+ +  ++++LE+EL ++Q  +E +K KYE+E++ R  +ENEFV +KKDVD A
Sbjct: 144 INNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEA 203

Query: 233 FLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEI 292
           ++ K +LE+  E L  EI+FL+ LYEEEI  LQSQIS+TSV++ MDNSR LD+D IIAE+
Sbjct: 204 YMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEV 263

Query: 293 KAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETEN 352
           KAQY+DIA+RS+AEAE+ YQ +YEEL+  AG H D+LR  K EI EMN+ I RLQ E E 
Sbjct: 264 KAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEG 323

Query: 353 VKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLG 412
           +K QR  LE AIA+AEQ+GE A+ DA  KL+ LE ALQ+AKQDMA  L+EYQE+MN KL 
Sbjct: 324 LKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLA 383

Query: 413 LDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKG 447
           LDIEIATYR+LLEGEE RL  G+  ++I   ++ G
Sbjct: 384 LDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSG 418


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  416 bits (1069), Expect = e-116
 Identities = 248/499 (49%), Positives = 326/499 (65%), Gaps = 40/499 (8%)

Query: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSAC----ITPVT 96
           GG R +      GS      GFGR R AS   G++ G    LG+ C PS C    I  VT
Sbjct: 52  GGARSISFNVASGSGWAGGYGFGRGR-ASGFAGSMFG-SVALGSVC-PSLCPPGGIHQVT 108

Query: 97  INESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQ 156
           IN+SLL PL +E+DP +Q+V+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKW  +Q
Sbjct: 109 INKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQ 168

Query: 157 QQRC--CQTNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSL 214
           Q     C+ N+EPI EGYIS LR+QL+ +SGDRVRL+SEL S++  +E YKK+YEEE++ 
Sbjct: 169 QLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINK 228

Query: 215 RPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVI 274
           R   ENEFV LKKDVD A+  K +L+   +AL  EI F K LYE E   +QS IS+TS+I
Sbjct: 229 RTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSII 288

Query: 275 VKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKN 334
           + MDN+R LD+D IIAE++AQY++IA +SKAEAEA YQ +++EL++ AG H D+L++ KN
Sbjct: 289 LSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKN 348

Query: 335 EILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQ 394
           EI E+ +LIQRL+ E E+VK Q   LE AIA+AEQ+G+ AL DA+ KL  LE ALQ+AK+
Sbjct: 349 EISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKE 408

Query: 395 DMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSK------- 446
           ++A +L+EYQE+++ KL LDIEIATYR+LLEGEE R+  E    V+ISV +S        
Sbjct: 409 ELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGT 468

Query: 447 ---------GAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRK 497
                    G + Y P  V     S G     GGC + G+G     C P+G      G  
Sbjct: 469 GAGFGFSNAGTYGYWPSSV-----SGGYSMLPGGC-VTGSGN----CSPRGEARTRLGSA 518

Query: 498 SSMTLGAGG----SSPSHK 512
           S      G     SSP+ K
Sbjct: 519 SEFRDSQGKTLALSSPTKK 537


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  415 bits (1067), Expect = e-116
 Identities = 253/517 (48%), Positives = 343/517 (66%), Gaps = 34/517 (6%)

Query: 17  FSSYSAVMP--RMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCN-------VGFGRPRV 67
           FS  SAV+      +  A SKG     G R L +LG + S ++ +        GFGR R 
Sbjct: 17  FSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRGR- 75

Query: 68  ASRCGGTLPGFGYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTVQRVKRDEKEQ 123
           AS   G++ G    LG  C P+ C    I  VT+NESLL PL +E+DP +Q+V+  E+EQ
Sbjct: 76  ASGFAGSMFG-SVALGPVC-PTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQ 133

Query: 124 IKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEGYISALRRQLD 181
           IK LNN+FASFI+KVRFLEQ+N++LETKW  +QQ     C+ N+EPI EGYIS LR+QL+
Sbjct: 134 IKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLE 193

Query: 182 CVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLET 241
            +SGDRVRL+SEL +++  +E YKK+YEEE++ R   ENEFV LKKDVD A+  K +L+ 
Sbjct: 194 TLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQA 253

Query: 242 NAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIAS 301
             E++ QEI F + L+E EI  +QS IS+ SVI+ MDN+R LD+D II E++ QY++IA 
Sbjct: 254 KVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIAL 313

Query: 302 RSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLE 361
           +SKAEAEA YQ +++EL++ AG H D+L+N KNEI E+ +LIQR++ E ENVK Q   LE
Sbjct: 314 KSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLE 373

Query: 362 GAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYR 421
            AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+M+ KL LD+EIATYR
Sbjct: 374 TAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYR 433

Query: 422 RLLEGEEHRLC-EGIGPVNIS-VSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGE 479
           +LLE EE R+  E   PV+IS +SS+ G  +Y   G    ++S G + ++  C I G   
Sbjct: 434 KLLESEECRMSGEFPSPVSISIISSTSGGSVY---GFRPSMVSGGYVANSSNC-ISGV-- 487

Query: 480 LYVPCEPQG--LLSCGSGRKSSMTLGAGG--SSPSHK 512
               C  +G    S GS      TLG G   S+PS K
Sbjct: 488 ----CSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKK 520


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  410 bits (1054), Expect = e-114
 Identities = 237/488 (48%), Positives = 313/488 (64%), Gaps = 41/488 (8%)

Query: 13  GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCG 72
           GSQ+ +S+S+V         VS+     GG       G  GSRSL N+G  +    S  G
Sbjct: 26  GSQARTSFSSV--------TVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISVSVAG 77

Query: 73  GTLPG-------FGYR-----------LGATCGPSACITPVTINESLLVPLALEIDPTVQ 114
           G L G       FG R            G  C P   I  VT+N+SLL PL +EIDP +Q
Sbjct: 78  GALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGG-IQEVTVNQSLLTPLHVEIDPEIQ 136

Query: 115 RVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQR----CCQTNIEPIFE 170
           RV+  E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +Q+Q       + N+EP+FE
Sbjct: 137 RVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFE 196

Query: 171 GYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVD 230
            Y+ ++R  LD +  +R RL+SEL ++Q  +E +K KYE+E++     ENEFV LKKDVD
Sbjct: 197 AYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVD 256

Query: 231 TAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIA 290
            A++ + DL      L QEIDFL+ LYE E+  +Q+ +S T+V++ MDN+R LD+D IIA
Sbjct: 257 AAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIA 316

Query: 291 EIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQET 350
           E+KAQY+ IA RS+AEAEAWYQ +YEEL+VTAG H DNLR+ KNEI E+ + IQRLQ E 
Sbjct: 317 EVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEA 376

Query: 351 ENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSK 410
           +  K Q  +L+ AIAEAEQ+GE AL DA+ KL  L+ AL +AK+D+  LL++YQE+MN K
Sbjct: 377 DAAKKQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVK 436

Query: 411 LGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470
           L LD+EIATYR+LLE EE R+  G  P  +S+S +         G ST V   G     G
Sbjct: 437 LALDVEIATYRKLLESEESRM-SGECPSAVSISVT---------GNSTTVCGGGAASFGG 486

Query: 471 GCSIVGTG 478
           G S+ G+G
Sbjct: 487 GISLGGSG 494


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  410 bits (1054), Expect = e-114
 Identities = 237/471 (50%), Positives = 305/471 (64%), Gaps = 37/471 (7%)

Query: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINES 100
           GG  G    G  G       GFG P      GG  PG         G    I  VTIN+S
Sbjct: 132 GGAGGFGGPGGFGGSG----GFGGPGSLGSPGGFGPG---------GFPGGIQEVTINQS 178

Query: 101 LLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC 160
           LL PL +EIDP + +VK  E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKWN +QQQ  
Sbjct: 179 LLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGT 238

Query: 161 CQ----TNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRP 216
                  N+EP+FE +I+ LR  LD + G+R RL+SEL +++  +E +KKKYE+E++ R 
Sbjct: 239 SSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRT 298

Query: 217 CVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVK 276
             ENEFV LKKDVD+A++ K +L+   +AL+ EIDFL++LY+ E+  +QS IS+TSV++ 
Sbjct: 299 AAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLS 358

Query: 277 MDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEI 336
           MDN+R LD+D IIAE++AQY+DIA RSKAEAEA YQ +  EL+ TAG H D+LRN K+EI
Sbjct: 359 MDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEI 418

Query: 337 LEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDM 396
           +E+N++IQRL+ E E VK Q   L+ AIAEAEQ GE AL DA  KL  L+ ALQ+AK D+
Sbjct: 419 IELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDL 478

Query: 397 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCG 455
           A LL++YQE+MN KL LD+EIATYR+LLEGEE+R+  E    V+ISV SS          
Sbjct: 479 ARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSS--------- 529

Query: 456 VSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGG 506
            +T   + G     GG    G G         G  S G G  S    G GG
Sbjct: 530 -TTSASAGGYGGGYGGGMGGGLG---------GGFSAGGGSGSGFGRGGGG 570



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 28/81 (34%), Positives = 37/81 (45%), Gaps = 7/81 (8%)

Query: 13 GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRA-LGCLGSRSLCNVGFGRP-RVASR 70
          GSQ FS  SAV+        V+      GG  G R+  G  GSRSL N+G  +   ++  
Sbjct: 12 GSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVA 71

Query: 71 CGGTLPGFGYRLGATCGPSAC 91
           GG+  G     G   G S+C
Sbjct: 72 AGGSRAG-----GFGGGRSSC 87


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  407 bits (1047), Expect = e-114
 Identities = 249/522 (47%), Positives = 333/522 (63%), Gaps = 36/522 (6%)

Query: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVS-KGPCRPGGGRGLRALGCLG-SRSLCNVGFG 63
           F  G R G   FS  SAV+   +   + S +   +     G ++L CLG SRSL      
Sbjct: 8   FPRGERLG---FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA----- 59

Query: 64  RPRVASRCGGTLPGF------GYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTV 113
               A R GG L GF         LG  C PS C    I  VT+N+SLL PL +E+DP +
Sbjct: 60  LSAAARRGGGRLGGFVGTAFGSAGLGPKC-PSVCPPGGIPQVTVNKSLLAPLNVEMDPEI 118

Query: 114 QRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEG 171
           QRV+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKWN +QQ     C+ N+EPI+EG
Sbjct: 119 QRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEG 178

Query: 172 YISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDT 231
           YIS L++QL+ +SGD VRL+SEL ++Q  +E YKK+YE E++ R   ENEFV LKKDVD 
Sbjct: 179 YISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDA 238

Query: 232 AFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAE 291
           A++ K +L+   ++L  EI F K LYE EI  +QS IS+TS+++ MDN+R+LD+D IIAE
Sbjct: 239 AYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAE 298

Query: 292 IKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETE 351
           ++AQY++IA +SKAEAE  YQ + +EL+VTAG H D+L+  K EI E+N+LIQR++ E  
Sbjct: 299 VRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIG 358

Query: 352 NVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKL 411
           NVK Q   LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+++ KL
Sbjct: 359 NVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKL 418

Query: 412 GLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470
            LD+EIATYR+LLE EE R+  E    V+ISV SS  A      G      S G     G
Sbjct: 419 ALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA------GAGGAGFSMGF----G 468

Query: 471 GCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512
             S           + +G  SCGS  K  +   +G S  + K
Sbjct: 469 ASSSYSYKTAAADVKTKG--SCGSELKDPLAKTSGSSCATKK 508


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  407 bits (1047), Expect = e-114
 Identities = 249/522 (47%), Positives = 333/522 (63%), Gaps = 36/522 (6%)

Query: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVS-KGPCRPGGGRGLRALGCLG-SRSLCNVGFG 63
           F  G R G   FS  SAV+   +   + S +   +     G ++L CLG SRSL      
Sbjct: 8   FPRGERLG---FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA----- 59

Query: 64  RPRVASRCGGTLPGF------GYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTV 113
               A R GG L GF         LG  C PS C    I  VT+N+SLL PL +E+DP +
Sbjct: 60  LSAAARRGGGRLGGFVGTAFGSAGLGPKC-PSVCPPGGIPQVTVNKSLLAPLNVEMDPEI 118

Query: 114 QRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEG 171
           QRV+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKWN +QQ     C+ N+EPI+EG
Sbjct: 119 QRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEG 178

Query: 172 YISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDT 231
           YIS L++QL+ +SGD VRL+SEL ++Q  +E YKK+YE E++ R   ENEFV LKKDVD 
Sbjct: 179 YISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDA 238

Query: 232 AFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAE 291
           A++ K +L+   ++L  EI F K LYE EI  +QS IS+TS+++ MDN+R+LD+D IIAE
Sbjct: 239 AYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAE 298

Query: 292 IKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETE 351
           ++AQY++IA +SKAEAE  YQ + +EL+VTAG H D+L+  K EI E+N+LIQR++ E  
Sbjct: 299 VRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIG 358

Query: 352 NVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKL 411
           NVK Q   LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+++ KL
Sbjct: 359 NVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKL 418

Query: 412 GLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470
            LD+EIATYR+LLE EE R+  E    V+ISV SS  A      G      S G     G
Sbjct: 419 ALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA------GAGGAGFSMGF----G 468

Query: 471 GCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512
             S           + +G  SCGS  K  +   +G S  + K
Sbjct: 469 ASSSYSYKTAAADVKTKG--SCGSELKDPLAKTSGSSCATKK 508


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  407 bits (1045), Expect = e-113
 Identities = 238/472 (50%), Positives = 313/472 (66%), Gaps = 28/472 (5%)

Query: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYR--LGATCGPSACITPVTIN 98
           GGG G    G  GS      GFG        GG   G GY    G  C P   I  VTIN
Sbjct: 111 GGGIGGGGFGGFGSGG---GGFG--------GGGFGGGGYGGGYGPVCPPGG-IQEVTIN 158

Query: 99  ESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ 158
           +SLL PL +EIDP +Q+VK  E+EQIK LNN+FASFI+KVRFLEQ+N++L+TKW  +QQ 
Sbjct: 159 QSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQV 218

Query: 159 RCCQT--NIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRP 216
                  N+EP FE +I+ LRR++D +  D+ RL+SEL ++Q  +E Y+ KYE+E++ R 
Sbjct: 219 DTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRT 278

Query: 217 CVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVK 276
             ENEFV +KKDVD A++ K DL+   + L QEIDFL +LY+ E+  +Q+QISET+VI+ 
Sbjct: 279 NAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILS 338

Query: 277 MDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEI 336
           MDN+R LD+D IIAE+KAQY+DIA +SKAEAE+ YQ +YEEL++TAG H D++RN K EI
Sbjct: 339 MDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEI 398

Query: 337 LEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDM 396
            E+N++IQRL+ E +NVK Q   L+ +I++AEQ+GE AL DAK KL  LE+ALQ+AK+D+
Sbjct: 399 SELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDL 458

Query: 397 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGV 456
           A LL++YQE+MN+KL LD+EIATYR LLEGEE R+     P N+SVS S           
Sbjct: 459 ARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAP-NVSVSVS----------T 507

Query: 457 STPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSS 508
           S   +S G  R  GG    G+G            S G G     + G+GGSS
Sbjct: 508 SHTTISGGGSRGGGGGG-YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSS 558


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  404 bits (1037), Expect = e-112
 Identities = 230/483 (47%), Positives = 322/483 (66%), Gaps = 32/483 (6%)

Query: 16  SFSSYSAVMPR-----MVTHYAVSKGPCRPGGGRGLRALGCLGSRSLC-NVGFGRPRVAS 69
           +FS +SAV+PR     + ++ A  +G     G R L +LG  G+R +  NV  G  R   
Sbjct: 15  NFSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLG--GNRRISFNVAGGGVRAGG 72

Query: 70  RCGGTLPGFGYRLGATCG-------------------PSACITPVTINESLLVPLALEID 110
              G  PG GY  G   G                   P   I  VT+N+SLL PL +E+D
Sbjct: 73  Y--GFRPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELD 130

Query: 111 PTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPI 168
           P +Q+V+  E+EQIK LN++FASFI+KVRFLEQ+N++LETKW  +QQ     C+ N+EPI
Sbjct: 131 PEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPI 190

Query: 169 FEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKD 228
            EGYIS LR+QL+ +SGDRVRL+SEL S++  +E YKK+YE E++ R   ENEFV LKKD
Sbjct: 191 LEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKD 250

Query: 229 VDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGI 288
            D A+ +K +L+   ++L +EI FLK LY+ EI  +Q+  SETSVI+ MDN+R+LD+D I
Sbjct: 251 ADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSI 310

Query: 289 IAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQ 348
           IAE++  Y++IA +SKAEAEA YQ + +EL++ A  H D+L++ ++E++E+N+LIQR++ 
Sbjct: 311 IAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRC 370

Query: 349 ETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMN 408
           E  NVK QR  LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+M+
Sbjct: 371 EIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMS 430

Query: 409 SKLGLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLR 467
            KL LD+EIATYR+LLEGEE R+  E    V+ISV SS     + P      + ++ V  
Sbjct: 431 LKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAG 490

Query: 468 SNG 470
           S+G
Sbjct: 491 SSG 493


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  400 bits (1029), Expect = e-111
 Identities = 233/492 (47%), Positives = 320/492 (65%), Gaps = 53/492 (10%)

Query: 42  GGRGLRALGCLGSRSLCNV-----------------------GFGRPRVASRCGGTLPGF 78
           GG G  + G  GSRSL N+                       GFG        GG+  G 
Sbjct: 111 GGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGK 170

Query: 79  GYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKV 138
           G      C P+  I  VTIN+SLL PL +EIDP +Q+V+ +E+EQIK LNN+FASFI+KV
Sbjct: 171 GGPGFPVC-PAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKV 229

Query: 139 RFLEQKNKLLETKWNFMQQQRCCQT--NIEPIFEGYISALRRQLDCVSGDRVRLESELCS 196
           +FLEQ+NK+LETKWN +QQQ    +  N+EP+FE Y+S LR+QLD +  D+ RL+SEL +
Sbjct: 230 QFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKT 289

Query: 197 LQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSL 256
           +Q ++E +K KYEEE++ R   EN+FV LKKDVD A+L K +LE   ++L  EI+FLK L
Sbjct: 290 MQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVL 349

Query: 257 YEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYE 316
           Y+ E+  +Q+ +S+TSV++ MDN+R LD+D IIAE++AQY++IA RSKAEAEA YQ + +
Sbjct: 350 YDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQ 409

Query: 317 ELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALN 376
           +L+++   H DNL+N K+EI E+N++IQRL+ E EN+K Q   L+ ++A+AEQ+GE AL 
Sbjct: 410 QLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALK 469

Query: 377 DAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-EGI 435
           DA  K   LE ALQ+AK+++A +L+EYQE+M+ KL LDIEIATYR+LLEGEE+R+  E  
Sbjct: 470 DAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQ 529

Query: 436 GPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSG 495
             V+ISV S                 STG +  +GG   +G+G  +        LS G G
Sbjct: 530 SAVSISVVSGS--------------TSTGGI--SGG---LGSGSGFG-------LSSGFG 563

Query: 496 RKSSMTLGAGGS 507
             S    G GGS
Sbjct: 564 SGSGSGFGFGGS 575


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  396 bits (1018), Expect = e-110
 Identities = 236/480 (49%), Positives = 315/480 (65%), Gaps = 17/480 (3%)

Query: 41  GGGRGLRALGCLGSRSLCNVG-FGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINE 99
           GGGRG+ + G  G+      G FG P V    G      G+  G   G    I  V +N+
Sbjct: 107 GGGRGVGS-GFGGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGG---IQEVIVNQ 162

Query: 100 SLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQR 159
           SLL PL +EIDP + +VK  E+EQIK LNN+FASFI+KVRFLEQ+NK+LETKW  +QQQ 
Sbjct: 163 SLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQT 222

Query: 160 CCQ--TNIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPC 217
                +++EP FE YIS L +QLD + G+R  LE EL S+Q  +E +KKKYE+E++ R  
Sbjct: 223 TGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTA 282

Query: 218 VENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKM 277
            ENEFV LKKDVD AF+ K +L+   ++L  E+ FL++LYE E+  +QS  S+TSV++ M
Sbjct: 283 AENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSM 342

Query: 278 DNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEIL 337
           DN+R LD+  IIAE++AQY++IA RSK+EAEA YQ +  EL+ TAG H D+LRN K+EI+
Sbjct: 343 DNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIM 402

Query: 338 EMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMA 397
           E+N++IQRL+ E ENVK Q   L+ AIAEAEQ+GE AL DA  KL  L+ ALQKAK D+A
Sbjct: 403 ELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLA 462

Query: 398 CLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL---CEGIGPVNI--SVSSSKGAFLYE 452
            LL++YQE+MN KL LD+EIATYR+LLEGEE R+   C+    +++  +V+S+ G+    
Sbjct: 463 RLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGS-SGS 521

Query: 453 PCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512
             GV   V  +G     GG S   +    V     G    G G  SS + G  GSS S++
Sbjct: 522 SRGVFGGVSGSGSGGYKGGSSSSSSSGYGV----SGGSGSGYGGVSSGSTGGRGSSGSYQ 577



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 2/76 (2%)

Query: 14 SQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRA-LGCLGSRSLCNVGFGRPRVASRCG 72
          SQ FS  SAV+        V++     GG  G R+  G  GSRSL N+G  +    S   
Sbjct: 14 SQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAA 73

Query: 73 GTLPGFGYRLG-ATCG 87
          G+    G+  G ++CG
Sbjct: 74 GSSRAGGFGGGRSSCG 89


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  389 bits (999), Expect = e-108
 Identities = 222/453 (49%), Positives = 301/453 (66%), Gaps = 23/453 (5%)

Query: 61  GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120
           GFG P      GG  PG G+  G   G    I  V++N+SLL PL +++DP +Q VK  E
Sbjct: 125 GFGGPGGVGGLGG--PG-GFGPGGYPGG---IHEVSVNQSLLQPLNVKVDPEIQNVKAQE 178

Query: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQT--NIEPIFEGYISALRR 178
           +EQIK LNN+FASFI+KVRFLEQ+N++L+TKW  +QQ        N+EPIF+GYI +L+R
Sbjct: 179 REQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKR 238

Query: 179 QLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKAD 238
            LD ++ +R    SEL ++Q  +E YKKKYE+E++ R   EN+FV LKKDVD A+++K +
Sbjct: 239 YLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVE 298

Query: 239 LETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDD 298
           L++  + L QEI+FLK LY+ EI  +   +++T+VI+ MDNSR LD+D IIAE+KAQY++
Sbjct: 299 LQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEE 358

Query: 299 IASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRC 358
           IA RSK EAEA Y  +YEEL+VT G H D+L+  K EI E+N++IQRLQ E  +VK Q  
Sbjct: 359 IAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCK 418

Query: 359 KLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIA 418
            ++ AIA+AEQ+GE AL DA+ KL  LEEALQ+AK+D+A LL++YQE+MN KL LD+EIA
Sbjct: 419 NVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIA 478

Query: 419 TYRRLLEGEEHRLCEGIGP-VNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGT 477
           TYR+LLEGEE R+   +   V +SV+SS          +S+ V S      +GG      
Sbjct: 479 TYRKLLEGEECRMSGDLSSNVTVSVTSST---------ISSNVASKAAFGGSGGRGSSSG 529

Query: 478 GELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPS 510
           G         G  S GSG + S + G  G   S
Sbjct: 530 GGY-----SSGSSSYGSGGRQSGSRGGSGGGGS 557


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  372 bits (955), Expect = e-103
 Identities = 211/437 (48%), Positives = 294/437 (67%), Gaps = 12/437 (2%)

Query: 13  GSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNVGFGRPRVASRCG 72
           GS+S S    +M R  + +    G    GGGRG   +G  G+      GFG     +   
Sbjct: 66  GSRSISIN--LMGRSTSGFCQGGGVGGFGGGRGF-GVGSTGAGGFGGGGFGGAGFGTSNF 122

Query: 73  GTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFA 132
           G L GFG      C P   I  VTIN+SLL PL LE+DP +QR+K  E+EQI  LNN+FA
Sbjct: 123 G-LGGFG----PYCPPGG-IQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFA 176

Query: 133 SFINKVRFLEQKNKLLETKWNFMQQQRCCQ--TNIEPIFEGYISALRRQLDCVSGDRVRL 190
           SFI+KVRFLEQ+N++L+TKW  +QQ        N+EP+ E YI  LRRQ+D +S +++R 
Sbjct: 177 SFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQ 236

Query: 191 ESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEI 250
            +E+ S+Q  +E YK KYE+E++ R   EN+FV LKKDVD A++ K DLE+  + L  E+
Sbjct: 237 NAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEV 296

Query: 251 DFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAW 310
           +FLK L+  E+  +Q+ IS+T+VI+ MDN+R LD+D II  ++ QY+ IA RSK EAEA 
Sbjct: 297 NFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEAL 356

Query: 311 YQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQ 370
           YQ +Y+EL++TAG H D+L+N K EI E+N+ +QRLQ E  NVK Q  +++  I++AE++
Sbjct: 357 YQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEER 416

Query: 371 GEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHR 430
           GE AL DA  KL  LEEALQ++K+++A LL++YQ ++  KL LD+EIATYR+LLEGEE R
Sbjct: 417 GEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESR 476

Query: 431 LC-EGIGPVNISVSSSK 446
           +  E    V+ISV +S+
Sbjct: 477 MSGELQSHVSISVQNSQ 493


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  354 bits (909), Expect = 9e-98
 Identities = 219/484 (45%), Positives = 296/484 (61%), Gaps = 37/484 (7%)

Query: 33  VSKGPCRPGGGRGLRALGCLGSRSLCNVGFGR-----PRVASRCGGTLPGF-------GY 80
           +S  PCR   G   R+     SR     GF        R  +  GG L G        G 
Sbjct: 1   MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGG 60

Query: 81  RLGATCG-----------PSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNN 129
           RLG   G           P   I  VTIN++LL PL +EIDP  Q V+  E ++I+ LNN
Sbjct: 61  RLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNN 120

Query: 130 RFASFINKVRFLEQKNKLLETKWNFMQQQRCC--QTNIEPIFEGYISALRRQLDCVSGDR 187
           +FASFI+KVRFLEQ+NK+LETKW+ +QQQ     Q  +EP+FE  +  LR+QL+ + G+R
Sbjct: 121 QFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGER 180

Query: 188 VRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALV 247
             L++EL + +   E YK KYEEE   R  +EN+FV LKKDVD  FL K +LE   EAL 
Sbjct: 181 GALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALR 240

Query: 248 QEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEA 307
           + + FLK L EEE+  LQ+Q S+TSV++ MDN+R LD   II E++A+Y++IA  SKAEA
Sbjct: 241 EYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEA 300

Query: 308 EAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEA 367
           EA YQ +Y+EL+V+A  H D ++  K +I ++++ IQRLQ +TEN+K Q   L+ AI +A
Sbjct: 301 EALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDA 360

Query: 368 EQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGE 427
           EQ+GE AL DA+ K+  LE AL+ AKQ++A LL EYQE+ ++KL LD+EIATYRRLLEGE
Sbjct: 361 EQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGE 420

Query: 428 EHRLC-EGIGPVNIS-------VSSSKGAFLYEPCGVSTPVLSTG----VLRSNGGCSIV 475
           E R+  E    V IS       +S   G  L   CG+ +   S G     + + G   I+
Sbjct: 421 ECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIIL 480

Query: 476 GTGE 479
           G+G+
Sbjct: 481 GSGK 484


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  345 bits (886), Expect = 4e-95
 Identities = 226/522 (43%), Positives = 303/522 (58%), Gaps = 78/522 (14%)

Query: 6   FQPGSRCGSQSFSSYSAVMPRMVTHYAVS-KGPCRPGGGRGLRALGCLG-SRSLCNVGFG 63
           F  G R G   FS  SAV+   +   + S +   +     G ++L CLG SRSL      
Sbjct: 8   FPRGERLG---FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLA----- 59

Query: 64  RPRVASRCGGTLPGF------GYRLGATCGPSAC----ITPVTINESLLVPLALEIDPTV 113
               A R GG L GF         LG  C PS C    I  VT+N+SLL PL +E+DP +
Sbjct: 60  LSAAARRGGGRLGGFVGTAFGSAGLGPKC-PSVCPPGGIPQVTVNKSLLAPLNVEMDPEI 118

Query: 114 QRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRC--CQTNIEPIFEG 171
           QRV+  E+EQIK LNN+FASFI+KVRFLEQ+N++LETKWN +QQ     C+ N+EPI+EG
Sbjct: 119 QRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEG 178

Query: 172 YISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDT 231
           YIS L++QL+ +SGD VRL+SEL ++Q  +E YKK+YE E++ R   ENEFV LKKDVD 
Sbjct: 179 YISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDA 238

Query: 232 AFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAE 291
           A++ K +L+   ++L  EI F K LYE EI  +QS IS+TS+++ MDN+R+LD+D IIAE
Sbjct: 239 AYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAE 298

Query: 292 IKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETE 351
           ++AQY++IA +SKAEAE  YQ +  +                                  
Sbjct: 299 VRAQYEEIALKSKAEAETLYQTKCAD---------------------------------- 324

Query: 352 NVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKL 411
                   LE AIA+AEQ+G+ AL DA+ KL  LE AL +AK+++A +L+EYQE+++ KL
Sbjct: 325 --------LETAIADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKL 376

Query: 412 GLDIEIATYRRLLEGEEHRLC-EGIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNG 470
            LD+EIATYR+LLE EE R+  E    V+ISV SS  A      G      S G     G
Sbjct: 377 ALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNA------GAGGAGFSMGF----G 426

Query: 471 GCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSSPSHK 512
             S           + +G  SCGS  K  +   +G S  + K
Sbjct: 427 ASSSYSYKTAAADVKTKG--SCGSELKDPLAKTSGSSCATKK 466


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,325,482
Number of Sequences: 37866
Number of extensions: 910651
Number of successful extensions: 4711
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 124
Number of HSP's successfully gapped in prelim test: 332
Number of HSP's that attempted gapping in prelim test: 3479
Number of HSP's gapped (non-prelim): 1138
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.