Guide to the Human Genome
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Search of human proteins with 26051237

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26051237 nucleoporin 54kDa [Homo sapiens]
         (507 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26051237 nucleoporin 54kDa [Homo sapiens]                         1006   0.0  
gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]                  59   1e-08
gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]                  59   1e-08
gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]                  59   1e-08
gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens]                  59   1e-08
gi|89276766 trophinin isoform 5 [Homo sapiens]                         52   1e-06
gi|24497609 nucleoporin 62kDa [Homo sapiens]                           51   3e-06
gi|24497607 nucleoporin 62kDa [Homo sapiens]                           51   3e-06
gi|24497605 nucleoporin 62kDa [Homo sapiens]                           51   3e-06
gi|24497603 nucleoporin 62kDa [Homo sapiens]                           51   3e-06
gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]                49   8e-06
gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]           49   8e-06
gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo ...    49   1e-05
gi|109148552 keratin 3 [Homo sapiens]                                  48   2e-05
gi|55956899 keratin 9 [Homo sapiens]                                   47   4e-05
gi|192807292 keratin 24 [Homo sapiens]                                 46   7e-05
gi|119395754 keratin 5 [Homo sapiens]                                  46   7e-05
gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]    46   7e-05
gi|153791670 keratin 76 [Homo sapiens]                                 46   9e-05
gi|131412228 keratin 13 isoform b [Homo sapiens]                       46   9e-05
gi|131412225 keratin 13 isoform a [Homo sapiens]                       46   9e-05
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              45   2e-04
gi|33946327 nucleoporin 214kDa [Homo sapiens]                          43   6e-04
gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]                43   8e-04
gi|221219020 NYD-SP11 protein [Homo sapiens]                           42   0.001
gi|24430190 keratin 15 [Homo sapiens]                                  42   0.001
gi|47132620 keratin 2 [Homo sapiens]                                   42   0.001
gi|239752328 PREDICTED: hypothetical protein XP_002348200 [Homo ...    42   0.001
gi|239746841 PREDICTED: hypothetical protein XP_002344236 [Homo ...    42   0.001
gi|6679074 nucleoporin like 2 [Homo sapiens]                           42   0.001

>gi|26051237 nucleoporin 54kDa [Homo sapiens]
          Length = 507

 Score = 1006 bits (2600), Expect = 0.0
 Identities = 507/507 (100%), Positives = 507/507 (100%)

Query: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG 60
           MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG
Sbjct: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG 60

Query: 61  FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT 120
           FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT
Sbjct: 61  FGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT 120

Query: 121 ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC 180
           ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC
Sbjct: 121 ASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFNNNIPPVEFTQENPFCRFKAVGYSC 180

Query: 181 MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV 240
           MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV
Sbjct: 181 MPSNKDEDGLVVLVFNKKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEV 240

Query: 241 VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP 300
           VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP
Sbjct: 241 VIYVVERSPNGTSRRVPATTLYAHFEQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNP 300

Query: 301 PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE 360
           PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE
Sbjct: 301 PAGVDPIIWEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISE 360

Query: 361 LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE 420
           LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE
Sbjct: 361 LQKNQTTSVAKIAQYKRKLMDLSHRTLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGE 420

Query: 421 LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI 480
           LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI
Sbjct: 421 LNAPTQFKGRLNELMSQIRMQNHFGAVRSEERYYIDADLLREIKQHLKQQQEGLSHLISI 480

Query: 481 IKDDLEDIKLVEHGLNETIHIRGGVFS 507
           IKDDLEDIKLVEHGLNETIHIRGGVFS
Sbjct: 481 IKDDLEDIKLVEHGLNETIHIRGGVFS 507


>gi|56549645 nucleoporin 98kD isoform 4 [Homo sapiens]
          Length = 1726

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/156 (35%), Positives = 68/156 (43%), Gaps = 40/156 (25%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG- 62
           +FG P G       T +  G   GFGTTS  A    +F +  NTG  GLFG +Q K  G 
Sbjct: 5   SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTG--GLFGNSQTKPGGL 62

Query: 63  FGT--------------GFGTTTGTSTGL-GTG-LGTGL--------------GFGGFNT 92
           FGT              GFGT+TGT+  L GT   GT L              GFG F T
Sbjct: 63  FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122

Query: 93  QQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPT 128
                T+ GGLF       T SN   +T+ +L  P+
Sbjct: 123 ----STSSGGLFGTTN---TTSNPFGSTSGSLFGPS 151



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 61/182 (33%), Positives = 74/182 (40%), Gaps = 31/182 (17%)

Query: 10  GTSGTAAATAAPAGGFGG------------FGTTSTTAGSAFSFSAPT-----NTGTTGL 52
           GTS T   T  P G FG             FG  +TT  + FSF   +     +T T GL
Sbjct: 260 GTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGL 318

Query: 53  FGGTQ--NKGFGFGTGFGTTTGTSTGLGTGL--GTGLGFGGFNTQQQQQTTLGGLFSQPT 108
           FG TQ    G  FGT   T+TGT+ G GTGL   T  GFG   +       L    S  T
Sbjct: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378

Query: 109 QAP---TQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKG-----YFNNNIP 160
            AP   T S  L    +  S  ++ G  + A       L A +GT  G      F NN P
Sbjct: 379 SAPSFGTTSGGLFGFGTNTSGNSIFG-SKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP 437

Query: 161 PV 162
            +
Sbjct: 438 KI 439



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 41/94 (43%), Positives = 47/94 (50%), Gaps = 21/94 (22%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGG-TQNKGFGFG---TGFGTTTGTSTGLGTGLG 82
           G GTT+   GS+     P  +  TGLF   T N GF +G   T FGT+T   TG GT   
Sbjct: 220 GAGTTTGLFGSS-----PATSSATGLFSSSTTNSGFAYGQNKTAFGTST---TGFGTNP- 270

Query: 83  TGLGFGGFNTQQQQQTTLGGLFSQP-TQAPTQSN 115
                GG   QQ QQTT   LFS+P  QA T  N
Sbjct: 271 -----GGLFGQQNQQTT--SLFSKPFGQATTTQN 297



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 8   PSGTSGTAAATAAPAG---GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           P G  GTA  T+       G G FG T+T  G+  S     N  TT  FG +      FG
Sbjct: 327 PGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT--FGSSTTSAPSFG 384

Query: 65  T------GFGTTT------------GT-STGLGTGLGTGLGFGGFNTQQQQQTTLGG 102
           T      GFGT T            GT  TGLG G GT LG G  +     Q  +GG
Sbjct: 385 TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGG 441



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/149 (31%), Positives = 60/149 (40%), Gaps = 31/149 (20%)

Query: 40  SFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTG---LGTGLGTGLGFGGFNTQQQQ 96
           SF  P   GT G FG T    FG  TGFGTT+G + G    G+   TG  FG        
Sbjct: 5   SFGTPFGGGTGG-FGTTST--FGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NS 55

Query: 97  QTTLGGL-----FSQPTQAPT----------QSNQLINTASALSAPTLLGDERDAILAKW 141
           QT  GGL     FSQP  + +           +N L  TAS  +  +L   + +A     
Sbjct: 56  QTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTAS--TGTSLFSSQNNAFAQ-- 111

Query: 142 NQLQAFWGTGKGYFNNNIPPVEFTQENPF 170
           N+   F   G    +  +     T  NPF
Sbjct: 112 NKPTGFGNFGTSTSSGGLFGTTNTTSNPF 140



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 21/97 (21%)

Query: 3   FNFGAPSGTSGTAAATAAPAG----------------GFGGFGTTSTTAGSAFSFSAPTN 46
           F FG  +GT+ T   TA+                   GFG FGT ST++G  F     TN
Sbjct: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT-STSSGGLFG---TTN 134

Query: 47  TGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGT 83
           T T+  FG T    FG  +     TGT+       GT
Sbjct: 135 T-TSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGT 170


>gi|56549643 nucleoporin 98kD isoform 3 [Homo sapiens]
          Length = 937

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/156 (35%), Positives = 68/156 (43%), Gaps = 40/156 (25%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG- 62
           +FG P G       T +  G   GFGTTS  A    +F +  NTG  GLFG +Q K  G 
Sbjct: 5   SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTG--GLFGNSQTKPGGL 62

Query: 63  FGT--------------GFGTTTGTSTGL-GTG-LGTGL--------------GFGGFNT 92
           FGT              GFGT+TGT+  L GT   GT L              GFG F T
Sbjct: 63  FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122

Query: 93  QQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPT 128
                T+ GGLF       T SN   +T+ +L  P+
Sbjct: 123 ----STSSGGLFGTTN---TTSNPFGSTSGSLFGPS 151



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 46/124 (37%), Positives = 54/124 (43%), Gaps = 22/124 (17%)

Query: 10  GTSGTAAATAAPAGGFGG------------FGTTSTTAGSAFSFSAPT-----NTGTTGL 52
           GTS T   T  P G FG             FG  +TT  + FSF   +     +T T GL
Sbjct: 260 GTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGL 318

Query: 53  FGGTQ--NKGFGFGTGFGTTTGTSTGLGTGL--GTGLGFGGFNTQQQQQTTLGGLFSQPT 108
           FG TQ    G  FGT   T+TGT+ G GTGL   T  GFG   +       L    S  T
Sbjct: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378

Query: 109 QAPT 112
            AP+
Sbjct: 379 SAPS 382



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 41/94 (43%), Positives = 47/94 (50%), Gaps = 21/94 (22%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGG-TQNKGFGFG---TGFGTTTGTSTGLGTGLG 82
           G GTT+   GS+     P  +  TGLF   T N GF +G   T FGT+T   TG GT   
Sbjct: 220 GAGTTTGLFGSS-----PATSSATGLFSSSTTNSGFAYGQNKTAFGTST---TGFGTNP- 270

Query: 83  TGLGFGGFNTQQQQQTTLGGLFSQP-TQAPTQSN 115
                GG   QQ QQTT   LFS+P  QA T  N
Sbjct: 271 -----GGLFGQQNQQTT--SLFSKPFGQATTTQN 297



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 45/128 (35%), Positives = 54/128 (42%), Gaps = 30/128 (23%)

Query: 5   FGAPSGTS-GTAAATAAPA-----GGFGGFGTTS------TTAGSAFSFSAPTNTGTTGL 52
           FG  + TS GTA  T          GFG  G+T       TT GS+ + +    T + GL
Sbjct: 331 FGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTTSAPSFGTTSGGL 390

Query: 53  FGG---------TQNKGFGFGTG------FGT--TTGT-STGLGTGLGTGLGFGGFNTQQ 94
           FG          T    FGFGT       FG+    GT  TGLG G GT LG G  +   
Sbjct: 391 FGNKPTLTLGTNTNTSNFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFG 450

Query: 95  QQQTTLGG 102
             Q  +GG
Sbjct: 451 NNQPKIGG 458



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/149 (31%), Positives = 60/149 (40%), Gaps = 31/149 (20%)

Query: 40  SFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTG---LGTGLGTGLGFGGFNTQQQQ 96
           SF  P   GT G FG T    FG  TGFGTT+G + G    G+   TG  FG        
Sbjct: 5   SFGTPFGGGTGG-FGTTST--FGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NS 55

Query: 97  QTTLGGL-----FSQPTQAPT----------QSNQLINTASALSAPTLLGDERDAILAKW 141
           QT  GGL     FSQP  + +           +N L  TAS  +  +L   + +A     
Sbjct: 56  QTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTAS--TGTSLFSSQNNAFAQ-- 111

Query: 142 NQLQAFWGTGKGYFNNNIPPVEFTQENPF 170
           N+   F   G    +  +     T  NPF
Sbjct: 112 NKPTGFGNFGTSTSSGGLFGTTNTTSNPF 140



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 21/97 (21%)

Query: 3   FNFGAPSGTSGTAAATAAPAG----------------GFGGFGTTSTTAGSAFSFSAPTN 46
           F FG  +GT+ T   TA+                   GFG FGT ST++G  F     TN
Sbjct: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT-STSSGGLFG---TTN 134

Query: 47  TGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGT 83
           T T+  FG T    FG  +     TGT+       GT
Sbjct: 135 T-TSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGT 170



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 29/86 (33%), Positives = 33/86 (38%), Gaps = 13/86 (15%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNK-GFG 62
           NFG  + TSG +   + PA G  G        G    F      G   LFG  Q K G  
Sbjct: 407 NFGFGTNTSGNSIFGSKPAPGTLG-------TGLGAGFGTALGAGQASLFGNNQPKIGGP 459

Query: 63  FGTGFGTTTGTSTGLGTGLGTGLGFG 88
            GTG     G +T   T     LGFG
Sbjct: 460 LGTGAFGAPGFNTTTAT-----LGFG 480


>gi|21264365 nucleoporin 98kD isoform 1 [Homo sapiens]
          Length = 1800

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/156 (35%), Positives = 68/156 (43%), Gaps = 40/156 (25%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG- 62
           +FG P G       T +  G   GFGTTS  A    +F +  NTG  GLFG +Q K  G 
Sbjct: 5   SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTG--GLFGNSQTKPGGL 62

Query: 63  FGT--------------GFGTTTGTSTGL-GTG-LGTGL--------------GFGGFNT 92
           FGT              GFGT+TGT+  L GT   GT L              GFG F T
Sbjct: 63  FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122

Query: 93  QQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPT 128
                T+ GGLF       T SN   +T+ +L  P+
Sbjct: 123 ----STSSGGLFGTTN---TTSNPFGSTSGSLFGPS 151



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 61/182 (33%), Positives = 74/182 (40%), Gaps = 31/182 (17%)

Query: 10  GTSGTAAATAAPAGGFGG------------FGTTSTTAGSAFSFSAPT-----NTGTTGL 52
           GTS T   T  P G FG             FG  +TT  + FSF   +     +T T GL
Sbjct: 260 GTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGL 318

Query: 53  FGGTQ--NKGFGFGTGFGTTTGTSTGLGTGL--GTGLGFGGFNTQQQQQTTLGGLFSQPT 108
           FG TQ    G  FGT   T+TGT+ G GTGL   T  GFG   +       L    S  T
Sbjct: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378

Query: 109 QAP---TQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKG-----YFNNNIP 160
            AP   T S  L    +  S  ++ G  + A       L A +GT  G      F NN P
Sbjct: 379 SAPSFGTTSGGLFGFGTNTSGNSIFG-SKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP 437

Query: 161 PV 162
            +
Sbjct: 438 KI 439



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 41/94 (43%), Positives = 47/94 (50%), Gaps = 21/94 (22%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGG-TQNKGFGFG---TGFGTTTGTSTGLGTGLG 82
           G GTT+   GS+     P  +  TGLF   T N GF +G   T FGT+T   TG GT   
Sbjct: 220 GAGTTTGLFGSS-----PATSSATGLFSSSTTNSGFAYGQNKTAFGTST---TGFGTNP- 270

Query: 83  TGLGFGGFNTQQQQQTTLGGLFSQP-TQAPTQSN 115
                GG   QQ QQTT   LFS+P  QA T  N
Sbjct: 271 -----GGLFGQQNQQTT--SLFSKPFGQATTTQN 297



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 8   PSGTSGTAAATAAPAG---GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           P G  GTA  T+       G G FG T+T  G+  S     N  TT  FG +      FG
Sbjct: 327 PGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT--FGSSTTSAPSFG 384

Query: 65  T------GFGTTT------------GT-STGLGTGLGTGLGFGGFNTQQQQQTTLGG 102
           T      GFGT T            GT  TGLG G GT LG G  +     Q  +GG
Sbjct: 385 TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGG 441



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/149 (31%), Positives = 60/149 (40%), Gaps = 31/149 (20%)

Query: 40  SFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTG---LGTGLGTGLGFGGFNTQQQQ 96
           SF  P   GT G FG T    FG  TGFGTT+G + G    G+   TG  FG        
Sbjct: 5   SFGTPFGGGTGG-FGTTST--FGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NS 55

Query: 97  QTTLGGL-----FSQPTQAPT----------QSNQLINTASALSAPTLLGDERDAILAKW 141
           QT  GGL     FSQP  + +           +N L  TAS  +  +L   + +A     
Sbjct: 56  QTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTAS--TGTSLFSSQNNAFAQ-- 111

Query: 142 NQLQAFWGTGKGYFNNNIPPVEFTQENPF 170
           N+   F   G    +  +     T  NPF
Sbjct: 112 NKPTGFGNFGTSTSSGGLFGTTNTTSNPF 140



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 21/97 (21%)

Query: 3   FNFGAPSGTSGTAAATAAPAG----------------GFGGFGTTSTTAGSAFSFSAPTN 46
           F FG  +GT+ T   TA+                   GFG FGT ST++G  F     TN
Sbjct: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT-STSSGGLFG---TTN 134

Query: 47  TGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGT 83
           T T+  FG T    FG  +     TGT+       GT
Sbjct: 135 T-TSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGT 170


>gi|21264369 nucleoporin 98kD isoform 2 [Homo sapiens]
          Length = 920

 Score = 58.5 bits (140), Expect = 1e-08
 Identities = 56/156 (35%), Positives = 68/156 (43%), Gaps = 40/156 (25%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG- 62
           +FG P G       T +  G   GFGTTS  A    +F +  NTG  GLFG +Q K  G 
Sbjct: 5   SFGTPFGGGTGGFGTTSTFGQNTGFGTTSGGAFGTSAFGSSNNTG--GLFGNSQTKPGGL 62

Query: 63  FGT--------------GFGTTTGTSTGL-GTG-LGTGL--------------GFGGFNT 92
           FGT              GFGT+TGT+  L GT   GT L              GFG F T
Sbjct: 63  FGTSSFSQPATSTSTGFGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT 122

Query: 93  QQQQQTTLGGLFSQPTQAPTQSNQLINTASALSAPT 128
                T+ GGLF       T SN   +T+ +L  P+
Sbjct: 123 ----STSSGGLFGTTN---TTSNPFGSTSGSLFGPS 151



 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 61/182 (33%), Positives = 74/182 (40%), Gaps = 31/182 (17%)

Query: 10  GTSGTAAATAAPAGGFGG------------FGTTSTTAGSAFSFSAPT-----NTGTTGL 52
           GTS T   T  P G FG             FG  +TT  + FSF   +     +T T GL
Sbjct: 260 GTSTTGFGTN-PGGLFGQQNQQTTSLFSKPFGQATTTQNTGFSFGNTSTIGQPSTNTMGL 318

Query: 53  FGGTQ--NKGFGFGTGFGTTTGTSTGLGTGL--GTGLGFGGFNTQQQQQTTLGGLFSQPT 108
           FG TQ    G  FGT   T+TGT+ G GTGL   T  GFG   +       L    S  T
Sbjct: 319 FGVTQASQPGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTTFGSSTT 378

Query: 109 QAP---TQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKG-----YFNNNIP 160
            AP   T S  L    +  S  ++ G  + A       L A +GT  G      F NN P
Sbjct: 379 SAPSFGTTSGGLFGFGTNTSGNSIFG-SKPAPGTLGTGLGAGFGTALGAGQASLFGNNQP 437

Query: 161 PV 162
            +
Sbjct: 438 KI 439



 Score = 47.4 bits (111), Expect = 3e-05
 Identities = 41/94 (43%), Positives = 47/94 (50%), Gaps = 21/94 (22%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGG-TQNKGFGFG---TGFGTTTGTSTGLGTGLG 82
           G GTT+   GS+     P  +  TGLF   T N GF +G   T FGT+T   TG GT   
Sbjct: 220 GAGTTTGLFGSS-----PATSSATGLFSSSTTNSGFAYGQNKTAFGTST---TGFGTNP- 270

Query: 83  TGLGFGGFNTQQQQQTTLGGLFSQP-TQAPTQSN 115
                GG   QQ QQTT   LFS+P  QA T  N
Sbjct: 271 -----GGLFGQQNQQTT--SLFSKPFGQATTTQN 297



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 42/117 (35%), Positives = 48/117 (41%), Gaps = 24/117 (20%)

Query: 8   PSGTSGTAAATAAPAG---GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           P G  GTA  T+       G G FG T+T  G+  S     N  TT  FG +      FG
Sbjct: 327 PGGLFGTATNTSTGTAFGTGTGLFGQTNTGFGAVGSTLFGNNKLTT--FGSSTTSAPSFG 384

Query: 65  T------GFGTTT------------GT-STGLGTGLGTGLGFGGFNTQQQQQTTLGG 102
           T      GFGT T            GT  TGLG G GT LG G  +     Q  +GG
Sbjct: 385 TTSGGLFGFGTNTSGNSIFGSKPAPGTLGTGLGAGFGTALGAGQASLFGNNQPKIGG 441



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 47/149 (31%), Positives = 60/149 (40%), Gaps = 31/149 (20%)

Query: 40  SFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTG---LGTGLGTGLGFGGFNTQQQQ 96
           SF  P   GT G FG T    FG  TGFGTT+G + G    G+   TG  FG        
Sbjct: 5   SFGTPFGGGTGG-FGTTST--FGQNTGFGTTSGGAFGTSAFGSSNNTGGLFG------NS 55

Query: 97  QTTLGGL-----FSQPTQAPT----------QSNQLINTASALSAPTLLGDERDAILAKW 141
           QT  GGL     FSQP  + +           +N L  TAS  +  +L   + +A     
Sbjct: 56  QTKPGGLFGTSSFSQPATSTSTGFGFGTSTGTANTLFGTAS--TGTSLFSSQNNAFAQ-- 111

Query: 142 NQLQAFWGTGKGYFNNNIPPVEFTQENPF 170
           N+   F   G    +  +     T  NPF
Sbjct: 112 NKPTGFGNFGTSTSSGGLFGTTNTTSNPF 140



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 32/97 (32%), Positives = 40/97 (41%), Gaps = 21/97 (21%)

Query: 3   FNFGAPSGTSGTAAATAAPAG----------------GFGGFGTTSTTAGSAFSFSAPTN 46
           F FG  +GT+ T   TA+                   GFG FGT ST++G  F     TN
Sbjct: 79  FGFGTSTGTANTLFGTASTGTSLFSSQNNAFAQNKPTGFGNFGT-STSSGGLFG---TTN 134

Query: 47  TGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGT 83
           T T+  FG T    FG  +     TGT+       GT
Sbjct: 135 T-TSNPFGSTSGSLFGPSSFTAAPTGTTIKFNPPTGT 170


>gi|89276766 trophinin isoform 5 [Homo sapiens]
          Length = 1431

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 39/108 (36%), Positives = 48/108 (44%), Gaps = 9/108 (8%)

Query: 3    FNFGAPSGTS-GTAAATAAPAGGFGGFGTTSTTAGSAFSFSA-PTNTGTTGLFGGTQNKG 60
            F+FG    T+ G        AG  GG GT++  +G   + S      GT+  FGG     
Sbjct: 1197 FSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTS 1256

Query: 61   FGFGTGFGTTTGTSTGLGTGLGTGLGF-------GGFNTQQQQQTTLG 101
             GFG G GT+ G S GLGT  G G G        GG  T     +TLG
Sbjct: 1257 TGFGGGLGTSAGFSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLG 1304



 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/93 (35%), Positives = 42/93 (45%), Gaps = 8/93 (8%)

Query: 5   FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPT--NTGTTGLFGGTQNKGFG 62
           FG    +SG+   T + +  FGG   TST  G   S S     ++ T+  FGGT +    
Sbjct: 899 FGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSIC 958

Query: 63  F------GTGFGTTTGTSTGLGTGLGTGLGFGG 89
           F      G GFG    TS   G+ L T  GFGG
Sbjct: 959 FDGSPSTGAGFGGALNTSASFGSVLNTSTGFGG 991



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 40/102 (39%), Positives = 47/102 (46%), Gaps = 18/102 (17%)

Query: 5    FGAPSGTSGTAAATAAPAGGF-GGFGT---------TSTTAGSAFSFSAPTN--TGTTGL 52
            FG   GTS   +   + + GF GG GT         TST  G     SA  +   GT+  
Sbjct: 1219 FGGGLGTSAGFSGGLSTSSGFDGGLGTSAGFGGGPGTSTGFGGGLGTSAGFSGGLGTSAG 1278

Query: 53   FGG--TQNKGFGFGTG----FGTTTGTSTGLGTGLGTGLGFG 88
            FGG    + GFG G G    FG+T GTS G   GL T  GFG
Sbjct: 1279 FGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFG 1320



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 45/124 (36%), Positives = 54/124 (43%), Gaps = 28/124 (22%)

Query: 6    GAPSGTSGTAAA--TAAPAGG-------FGGFGTTSTTAGSAFS----FSAPTNTG---- 48
            G PS + G  AA  T+   GG       FGG  +TS   GSA +    F  P +T     
Sbjct: 1121 GTPSNSIGFGAAPSTSVSFGGAHGTSLCFGGAPSTSLCFGSASNTNLCFGGPPSTSACFS 1180

Query: 49   --TTGLF--GGTQNKGFGFGTGFGTTTG------TSTGLGTGLGTGLGF-GGFNTQQQQQ 97
              T+  F  G + + GF FG G  T  G      TS G G GLGT  GF GG +T     
Sbjct: 1181 GATSPSFCDGPSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLGTSAGFSGGLSTSSGFD 1240

Query: 98   TTLG 101
              LG
Sbjct: 1241 GGLG 1244



 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 32/87 (36%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 5    FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
            FG P  TS   +   +P+   G     ST+ G +F     TN G  G    +   G G G
Sbjct: 1169 FGGPPSTSACFSGATSPSFCDG----PSTSTGFSFGNGLSTNAGFGGGLNTSAGFGGGLG 1224

Query: 65   TGFGTTTG--TSTGLGTGLGTGLGFGG 89
            T  G + G  TS+G   GLGT  GFGG
Sbjct: 1225 TSAGFSGGLSTSSGFDGGLGTSAGFGG 1251



 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 8/94 (8%)

Query: 4    NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSA--PTNTGTTGLFGGTQNKGF 61
            +FG    TS     +   + GFGG  +TS + G + S SA       T+  F G+ + G 
Sbjct: 908  SFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGGSSSTSANFGGTLSTSICFDGSPSTGA 967

Query: 62   GFG------TGFGTTTGTSTGLGTGLGTGLGFGG 89
            GFG        FG+   TSTG G  + T   FGG
Sbjct: 968  GFGGALNTSASFGSVLNTSTGFGGAMSTSADFGG 1001



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 36/108 (33%), Positives = 45/108 (41%), Gaps = 17/108 (15%)

Query: 4    NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGF 63
            NFG    TS     + +   GFGG   TS + GS  +    T+TG    FGG  +    F
Sbjct: 948  NFGGTLSTSICFDGSPSTGAGFGGALNTSASFGSVLN----TSTG----FGGAMSTSADF 999

Query: 64   G------TGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFS 105
            G        FG + GTS   G+ L T  G+GG        T  GG  S
Sbjct: 1000 GGTLSTSVCFGGSPGTSVSFGSALNTNAGYGG---AVSTNTDFGGTLS 1044



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 40/120 (33%), Positives = 53/120 (44%), Gaps = 32/120 (26%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGGFG-GFG-TTSTTAG------------------SAFSF 41
           +F+ G  S  SG  + +A  +GG   GFG T STTAG                  + FS 
Sbjct: 822 SFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSS 881

Query: 42  SAPTNTGTTGL------FGGTQNKGFGFG------TGFGTTTGTSTGLGTGLGTGLGFGG 89
           +  T+TG  G+      FGG+ +    FG        FG +  TSTG G  L T + FGG
Sbjct: 882 ALSTSTGFGGILSTSVCFGGSPSSSGSFGGTLSTSICFGGSPCTSTGFGGTLSTSVSFGG 941



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 30/88 (34%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 4    NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTN--TGTTGLFGGTQNKGF 61
            +FG    TS     + + + GFGG   T+ + G A S SA  +    T+  F G      
Sbjct: 1038 DFGGTLSTSVCFGGSPSTSAGFGGALNTNASFGCAVSTSASFSGAVSTSACFSGAPITNP 1097

Query: 62   GFGTGFGTTTGTSTGLGTGLGTGLGFGG 89
            GFG  F     TS G G  L T   FGG
Sbjct: 1098 GFGGAF----STSAGFGGALSTAADFGG 1121



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 30/88 (34%), Positives = 37/88 (42%), Gaps = 6/88 (6%)

Query: 4    NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTN--TGTTGLFGGTQNKGF 61
            +FG    TS + +   + +  F G   T+   G AFS SA       T   FGGT +   
Sbjct: 1068 SFGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGGALSTAADFGGTPSNSI 1127

Query: 62   GFGTGFGTTTGTSTGLGTGLGTGLGFGG 89
                GFG    TS   G   GT L FGG
Sbjct: 1128 ----GFGAAPSTSVSFGGAHGTSLCFGG 1151



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 34/101 (33%), Positives = 44/101 (43%), Gaps = 16/101 (15%)

Query: 5    FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTG--TTGLFGGTQNKGF- 61
            F    GTS         + GFGG   T+ + GS    SA  + G  T+  FG   N  F 
Sbjct: 1269 FSGGLGTSAGFGGGLVTSDGFGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFD 1328

Query: 62   -------GFGTGFGTTTG------TSTGLGTGLGTGLGFGG 89
                   GFG+G  T+TG      TSTG  +G  + +GF G
Sbjct: 1329 RGLSTIIGFGSGSNTSTGFTGEPSTSTGFSSGPSSIVGFSG 1369



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 37/112 (33%), Positives = 51/112 (45%), Gaps = 27/112 (24%)

Query: 4    NFGAPSGTSGTAAATAAPAGGFG---------------GFGTTSTTAGSAFSFSAPTNTG 48
            +FG+  GTS   +   + + GFG               GFG+ S T+ + F+    T+TG
Sbjct: 1298 SFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTS-TGFTGEPSTSTG 1356

Query: 49   TTGL------FGGTQNKGFGFGTG---FGTTTGTSTGLGTGLG--TGLGFGG 89
             +        F G  + G GF +G    G + G STG G G G  TG GFGG
Sbjct: 1357 FSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAGFGGGPNTGAGFGG 1408



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 28/89 (31%), Positives = 37/89 (41%), Gaps = 6/89 (6%)

Query: 5    FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGF- 63
            FG   GT+ +  +T   + GF G  +TS   GS  + S      T   FG   N   GF 
Sbjct: 1289 FGGGLGTNASFGSTLGTSAGFSGGLSTSDGFGSRPNASFDRGLSTIIGFGSGSNTSTGFT 1348

Query: 64   -----GTGFGTTTGTSTGLGTGLGTGLGF 87
                  TGF +   +  G   G  TG+GF
Sbjct: 1349 GEPSTSTGFSSGPSSIVGFSGGPSTGVGF 1377



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 28/87 (32%), Positives = 39/87 (44%), Gaps = 8/87 (9%)

Query: 6    GAPSGTSGTAAATAAPAGGFGG----FGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGF 61
            G PS ++G ++  ++  G  GG     G  S  + S FS    T  G    FGG  N G 
Sbjct: 1349 GEPSTSTGFSSGPSSIVGFSGGPSTGVGFCSGPSTSGFSGGPSTGAG----FGGGPNTGA 1404

Query: 62   GFGTGFGTTTGTSTGLGTGLGTGLGFG 88
            GFG G  T+ G  +G  +    G  +G
Sbjct: 1405 GFGGGPSTSAGFGSGAASLGACGFSYG 1431



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 29/103 (28%), Positives = 38/103 (36%), Gaps = 18/103 (17%)

Query: 5    FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSA--PTNTGTTGLFGGTQNKGFG 62
            FG   GTS +  +      G+GG  +T+T  G   S S     +  T+  FGG  N    
Sbjct: 1009 FGGSPGTSVSFGSALNTNAGYGGAVSTNTDFGGTLSTSVCFGGSPSTSAGFGGALNTNAS 1068

Query: 63   FGTGFGTTTG----------------TSTGLGTGLGTGLGFGG 89
            FG    T+                  T+ G G    T  GFGG
Sbjct: 1069 FGCAVSTSASFSGAVSTSACFSGAPITNPGFGGAFSTSAGFGG 1111



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 33/125 (26%), Positives = 52/125 (41%), Gaps = 7/125 (5%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGF 61
           + +FG    TS + ++ A+ +  FG   +TST+  S  S S      T+  F G  +  F
Sbjct: 774 SISFGGTLSTSSSFSSAASIS--FGCAHSTSTSFSSEASISFGGMPCTSASFSGGVSSSF 831

Query: 62  G--FGTGFGTTTGTSTGLGTGLGTGLGFGGF---NTQQQQQTTLGGLFSQPTQAPTQSNQ 116
                T    + G S+G G  L T  GF G    +T      T   +FS      T    
Sbjct: 832 SGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSAPTTSTVFSSALSTSTGFGG 891

Query: 117 LINTA 121
           +++T+
Sbjct: 892 ILSTS 896



 Score = 33.5 bits (75), Expect = 0.47
 Identities = 38/139 (27%), Positives = 48/139 (34%), Gaps = 55/139 (39%)

Query: 6   GAPSGTSGTAAATAAPAGG-----FGGFGTTSTTAGSA---------------------- 38
           G P  T G A +T+A         FGG  +TS++  SA                      
Sbjct: 753 GGPGITFGVAPSTSASFSNTASISFGGTLSTSSSFSSAASISFGCAHSTSTSFSSEASIS 812

Query: 39  ----------------FSFSAPTNT------GTTGLFGGTQNKGFGF------GTGFGTT 70
                            SFS P +T      G +  FGGT +   GF       T FG+ 
Sbjct: 813 FGGMPCTSASFSGGVSSSFSGPLSTSATFSGGASSGFGGTLSTTAGFSGVLSTSTSFGSA 872

Query: 71  TGTSTGLGTGLGTGLGFGG 89
             TST   + L T  GFGG
Sbjct: 873 PTTSTVFSSALSTSTGFGG 891


>gi|24497609 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 53/148 (35%), Positives = 65/148 (43%), Gaps = 35/148 (23%)

Query: 3   FNFG---APSG--TSGTA-AATAAPAGGFGGFGTTSTTAGSAFSFSAP----TNTGTTGL 52
           FNFG   AP+G  T GTA  AT  PA GF    + ST+    F+F AP    T+T +TGL
Sbjct: 4   FNFGGTGAPTGGFTFGTAKTATTTPATGF----SFSTSGTGGFNFGAPFQPATSTPSTGL 59

Query: 53  FG------GTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQ 106
           F        TQ  GF FG      T T    GTG   G+G    N      T      + 
Sbjct: 60  FSLATQTPATQTTGFTFG------TATLASGGTGFSLGIGASKLNLSNTAATP---AMAN 110

Query: 107 PTQAPTQSNQLIN------TASALSAPT 128
           P+     S+ L N      T+S  +APT
Sbjct: 111 PSGFGLGSSNLTNAISSTVTSSQGTAPT 138



 Score = 30.0 bits (66), Expect = 5.2
 Identities = 39/144 (27%), Positives = 55/144 (38%), Gaps = 35/144 (24%)

Query: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSF--SAPTNTGTTGLF----- 53
           + F    P+ T+  A   AAP        T ++T  S F+   +APT++ TTGL      
Sbjct: 188 LPFTPATPAATTAGATQPAAPTPT----ATITSTGPSLFASIATAPTSSATTGLSLCTPV 243

Query: 54  -------GGTQN---KGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGL 103
                   GTQ    K  G  +G  TTT T+                 T     +T G  
Sbjct: 244 TTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATA------------TTTSSSSTTGFA 291

Query: 104 FSQPTQAPTQSNQLINTASALSAP 127
            +    AP       NTA+A++AP
Sbjct: 292 LNLKPLAPAGIPS--NTAAAVTAP 313


>gi|24497607 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 53/148 (35%), Positives = 65/148 (43%), Gaps = 35/148 (23%)

Query: 3   FNFG---APSG--TSGTA-AATAAPAGGFGGFGTTSTTAGSAFSFSAP----TNTGTTGL 52
           FNFG   AP+G  T GTA  AT  PA GF    + ST+    F+F AP    T+T +TGL
Sbjct: 4   FNFGGTGAPTGGFTFGTAKTATTTPATGF----SFSTSGTGGFNFGAPFQPATSTPSTGL 59

Query: 53  FG------GTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQ 106
           F        TQ  GF FG      T T    GTG   G+G    N      T      + 
Sbjct: 60  FSLATQTPATQTTGFTFG------TATLASGGTGFSLGIGASKLNLSNTAATP---AMAN 110

Query: 107 PTQAPTQSNQLIN------TASALSAPT 128
           P+     S+ L N      T+S  +APT
Sbjct: 111 PSGFGLGSSNLTNAISSTVTSSQGTAPT 138



 Score = 30.0 bits (66), Expect = 5.2
 Identities = 39/144 (27%), Positives = 55/144 (38%), Gaps = 35/144 (24%)

Query: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSF--SAPTNTGTTGLF----- 53
           + F    P+ T+  A   AAP        T ++T  S F+   +APT++ TTGL      
Sbjct: 188 LPFTPATPAATTAGATQPAAPTPT----ATITSTGPSLFASIATAPTSSATTGLSLCTPV 243

Query: 54  -------GGTQN---KGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGL 103
                   GTQ    K  G  +G  TTT T+                 T     +T G  
Sbjct: 244 TTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATA------------TTTSSSSTTGFA 291

Query: 104 FSQPTQAPTQSNQLINTASALSAP 127
            +    AP       NTA+A++AP
Sbjct: 292 LNLKPLAPAGIPS--NTAAAVTAP 313


>gi|24497605 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 53/148 (35%), Positives = 65/148 (43%), Gaps = 35/148 (23%)

Query: 3   FNFG---APSG--TSGTA-AATAAPAGGFGGFGTTSTTAGSAFSFSAP----TNTGTTGL 52
           FNFG   AP+G  T GTA  AT  PA GF    + ST+    F+F AP    T+T +TGL
Sbjct: 4   FNFGGTGAPTGGFTFGTAKTATTTPATGF----SFSTSGTGGFNFGAPFQPATSTPSTGL 59

Query: 53  FG------GTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQ 106
           F        TQ  GF FG      T T    GTG   G+G    N      T      + 
Sbjct: 60  FSLATQTPATQTTGFTFG------TATLASGGTGFSLGIGASKLNLSNTAATP---AMAN 110

Query: 107 PTQAPTQSNQLIN------TASALSAPT 128
           P+     S+ L N      T+S  +APT
Sbjct: 111 PSGFGLGSSNLTNAISSTVTSSQGTAPT 138



 Score = 30.0 bits (66), Expect = 5.2
 Identities = 39/144 (27%), Positives = 55/144 (38%), Gaps = 35/144 (24%)

Query: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSF--SAPTNTGTTGLF----- 53
           + F    P+ T+  A   AAP        T ++T  S F+   +APT++ TTGL      
Sbjct: 188 LPFTPATPAATTAGATQPAAPTPT----ATITSTGPSLFASIATAPTSSATTGLSLCTPV 243

Query: 54  -------GGTQN---KGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGL 103
                   GTQ    K  G  +G  TTT T+                 T     +T G  
Sbjct: 244 TTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATA------------TTTSSSSTTGFA 291

Query: 104 FSQPTQAPTQSNQLINTASALSAP 127
            +    AP       NTA+A++AP
Sbjct: 292 LNLKPLAPAGIPS--NTAAAVTAP 313


>gi|24497603 nucleoporin 62kDa [Homo sapiens]
          Length = 522

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 53/148 (35%), Positives = 65/148 (43%), Gaps = 35/148 (23%)

Query: 3   FNFG---APSG--TSGTA-AATAAPAGGFGGFGTTSTTAGSAFSFSAP----TNTGTTGL 52
           FNFG   AP+G  T GTA  AT  PA GF    + ST+    F+F AP    T+T +TGL
Sbjct: 4   FNFGGTGAPTGGFTFGTAKTATTTPATGF----SFSTSGTGGFNFGAPFQPATSTPSTGL 59

Query: 53  FG------GTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQ 106
           F        TQ  GF FG      T T    GTG   G+G    N      T      + 
Sbjct: 60  FSLATQTPATQTTGFTFG------TATLASGGTGFSLGIGASKLNLSNTAATP---AMAN 110

Query: 107 PTQAPTQSNQLIN------TASALSAPT 128
           P+     S+ L N      T+S  +APT
Sbjct: 111 PSGFGLGSSNLTNAISSTVTSSQGTAPT 138



 Score = 30.0 bits (66), Expect = 5.2
 Identities = 39/144 (27%), Positives = 55/144 (38%), Gaps = 35/144 (24%)

Query: 1   MAFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSF--SAPTNTGTTGLF----- 53
           + F    P+ T+  A   AAP        T ++T  S F+   +APT++ TTGL      
Sbjct: 188 LPFTPATPAATTAGATQPAAPTPT----ATITSTGPSLFASIATAPTSSATTGLSLCTPV 243

Query: 54  -------GGTQN---KGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGL 103
                   GTQ    K  G  +G  TTT T+                 T     +T G  
Sbjct: 244 TTAGAPTAGTQGFSLKAPGAASGTSTTTSTAATATA------------TTTSSSSTTGFA 291

Query: 104 FSQPTQAPTQSNQLINTASALSAP 127
            +    AP       NTA+A++AP
Sbjct: 292 LNLKPLAPAGIPS--NTAAAVTAP 313


>gi|30102928 nucleoporin like 1 isoform a [Homo sapiens]
          Length = 599

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 44/138 (31%), Positives = 58/138 (42%), Gaps = 28/138 (20%)

Query: 3   FNFGAPSGTSGTAAATAAPAGG-----------------FGGFGTTSTTAGSAFSFSAPT 45
           F+FG+ +  S T AA     GG                 FG  G+TST A +    SAP+
Sbjct: 5   FSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATT----SAPS 60

Query: 46  NTGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFS 105
           +   TGLFG     GF  G       GT+TG+ T + TGL  G   T     T     F+
Sbjct: 61  SGFGTGLFGSKPATGFTLG-------GTNTGIATTITTGLTLGTPATTSAATTGFSLGFN 113

Query: 106 QPTQAPTQSNQLINTASA 123
           +P  + T     I + SA
Sbjct: 114 KPAASATPFALPITSTSA 131



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 39/121 (32%), Positives = 46/121 (38%), Gaps = 17/121 (14%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG---------TTTGTSTGL 77
           GF   S T GS    +  T+TG    FG   +     G  FG         TT+  S+G 
Sbjct: 4   GFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPSSGF 63

Query: 78  GTGL-----GTGLGFGGFNTQQQQQTTLGGLFSQP--TQAPTQSNQL-INTASALSAPTL 129
           GTGL      TG   GG NT      T G     P  T A T    L  N  +A + P  
Sbjct: 64  GTGLFGSKPATGFTLGGTNTGIATTITTGLTLGTPATTSAATTGFSLGFNKPAASATPFA 123

Query: 130 L 130
           L
Sbjct: 124 L 124



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 13/65 (20%)

Query: 3   FNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGL-FGGTQNKGF 61
           F FG  +  SG+ +A         GFG++ST   S F+FS P  T + GL FG +     
Sbjct: 529 FGFGTTNKPSGSLSA---------GFGSSST---SGFNFSNPGITASAGLTFGVSNPASA 576

Query: 62  GFGTG 66
           GFGTG
Sbjct: 577 GFGTG 581



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 20/121 (16%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           SG + ++A T+ PA       +T  T  +    +A T T +TGL  G    G G      
Sbjct: 132 SGLTLSSALTSTPAA------STGFTLNNLGGTTATTTTASTGLSLGGALAGLGGSLFQS 185

Query: 69  TTTGTS----TGLGTGLGT----------GLGFGGFNTQQQQQTTLGGLFSQPTQAPTQS 114
           T TGTS      LG  LGT          GLG   F++   +++   G   + ++A    
Sbjct: 186 TNTGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSDKTGTRPEDSKALKDE 245

Query: 115 N 115
           N
Sbjct: 246 N 246



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/114 (32%), Positives = 45/114 (39%), Gaps = 19/114 (16%)

Query: 8   PSGTSGTAAATAAPAG-------GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG 60
           P  T   AAA A  A          G   +   + G+ F     T   ++GL G +   G
Sbjct: 454 PFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGL-GSSNLGG 512

Query: 61  FGFGTGFG-TTTGTST-GLGT------GLGTGLG---FGGFNTQQQQQTTLGGL 103
           FG  +GFG +TTG ST G GT       L  G G     GFN      T   GL
Sbjct: 513 FGTSSGFGCSTTGASTFGFGTTNKPSGSLSAGFGSSSTSGFNFSNPGITASAGL 566


>gi|26051278 nuclear pore membrane protein 121 [Homo sapiens]
          Length = 984

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGF 61
           AF+FGA  G SG+ A +   AGG G     +T   + F+F+  + T +  +FGGT    F
Sbjct: 861 AFSFGA--GQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVSSTTESKPVFGGTATPTF 918

Query: 62  GFGT---GFGTTTGTSTGLGTGLGTGLGFGG 89
           G  T   G G T+G+S   G       GF G
Sbjct: 919 GLNTPAPGVG-TSGSSLSFGASSAPAQGFVG 948



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 36/113 (31%), Positives = 45/113 (39%), Gaps = 25/113 (22%)

Query: 5   FGAPSGTS---GTAAATAAPAGGFGGFGTTSTTAGSAFSFS----------------APT 45
           FGAP+ +    G + A    A    GFG T+ TA S  S S                AP 
Sbjct: 782 FGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPA 841

Query: 46  NTGTTGLF-----GGTQNKGFGFGTGFGTTTGTSTGLGTGLG-TGLGFGGFNT 92
            +G+ G+        T    F FG G   +T TST    GLG   LG  G +T
Sbjct: 842 GSGSFGINVATPGSSTTTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQST 894



 Score = 35.8 bits (81), Expect = 0.094
 Identities = 33/103 (32%), Positives = 42/103 (40%), Gaps = 20/103 (19%)

Query: 10  GTSGTAAATAAPAGGFGGFG-TTSTTAGSAFS--FSAPTNTGTTG----LFGGTQNKGFG 62
           G   TA+A  APA     FG +T+   G+A S  F A T T ++G    +FG T    F 
Sbjct: 774 GLKATASAFGAPASSQPAFGGSTAVFFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFT 833

Query: 63  FGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFS 105
           FG             G+    G G  G N      +T  G FS
Sbjct: 834 FG-------------GSAAPAGSGSFGINVATPGSSTTTGAFS 863


>gi|239743232 PREDICTED: hypothetical protein XP_002342775 [Homo
           sapiens]
          Length = 834

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/91 (36%), Positives = 45/91 (49%), Gaps = 6/91 (6%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGF 61
           AF+FGA  G SG+ A +   AGG G     +T   + F+F+  + T +  +FGGT    F
Sbjct: 711 AFSFGA--GQSGSTATSTPFAGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTF 768

Query: 62  GFGT---GFGTTTGTSTGLGTGLGTGLGFGG 89
           G  T   G G T+G+S   G       GF G
Sbjct: 769 GLNTPAPGVG-TSGSSLSFGASSAPAQGFVG 798



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 30/97 (30%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 3   FNFGAPSGTS-GTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNK-- 59
           F+FGA + +  G    TA+       FG+T+ +  +    +AP  +G+ G+   T     
Sbjct: 648 FSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSA 707

Query: 60  ---GFGFGTGFGTTTGTSTGLGTGLG-TGLGFGGFNT 92
               F FG G   +T TST    GLG   LG  G +T
Sbjct: 708 TTGAFSFGAGQSGSTATSTPFAGGLGQNALGTTGQST 744


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 57/194 (29%), Positives = 72/194 (37%), Gaps = 35/194 (18%)

Query: 3   FNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGS-AFSFSAPTNTGTTGLFGGTQNKGF 61
           +N G     S + AA  + AGGFGG  ++   AG     F +    G  G FGG +  G 
Sbjct: 58  YNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGG 117

Query: 62  GFG--TGFGTTTGTSTGLGTG----------------LGT--GLGFGGFNTQQQQQTTLG 101
           GFG   GFG   G     G G                LG+  G G GGF    Q+ T   
Sbjct: 118 GFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQEVTINQ 177

Query: 102 GLFS--------QPTQAPTQSNQLINT-----ASALSAPTLLGDERDAILAKWNQLQAFW 148
            L          Q  Q   Q  + I T     AS +     L  +   +  KWN LQ   
Sbjct: 178 SLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQ-Q 236

Query: 149 GTGKGYFNNNIPPV 162
           GT      NN+ P+
Sbjct: 237 GTSSISGTNNLEPL 250



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 29/91 (31%), Positives = 36/91 (39%), Gaps = 11/91 (12%)

Query: 10  GTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNK---------- 59
           G  G A    + AGGFG     +     + S S        G FGG ++           
Sbjct: 37  GAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGG 96

Query: 60  -GFGFGTGFGTTTGTSTGLGTGLGTGLGFGG 89
            G G+G GFG   G   G+G G G   GFGG
Sbjct: 97  FGSGYGGGFGGGFGGGRGMGGGFGGAGGFGG 127



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 31/98 (31%), Positives = 49/98 (50%), Gaps = 3/98 (3%)

Query: 14  TAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTG-FGTTTG 72
           +++ T+A AGG+GG        G    FSA   +G+    GG    G GFG G  G + G
Sbjct: 527 SSSTTSASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSGG 586

Query: 73  TSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQA 110
           +  G  +G   G+  GGF++   +  ++   FSQ +Q+
Sbjct: 587 SGFGSISGARYGVSGGGFSSASNRGGSI--KFSQSSQS 622


>gi|55956899 keratin 9 [Homo sapiens]
          Length = 623

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 35/90 (38%), Positives = 41/90 (45%), Gaps = 6/90 (6%)

Query: 5   FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGL----FGGTQNKG 60
           F + SG  G ++      GG G FG  S   GS   FSA +  G  G     FGG    G
Sbjct: 47  FSSSSGYGGGSSRVCGRGGG-GSFGY-SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGG 104

Query: 61  FGFGTGFGTTTGTSTGLGTGLGTGLGFGGF 90
           +    GFG   G  +G G G G G GFGGF
Sbjct: 105 YSSSGGFGGGFGGGSGGGFGGGYGSGFGGF 134



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 26/84 (30%), Positives = 38/84 (45%)

Query: 6   GAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGT 65
           G+  G+ G+    +   GG GG     +  G +       + G+ G +GG    G G G 
Sbjct: 511 GSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGG 570

Query: 66  GFGTTTGTSTGLGTGLGTGLGFGG 89
           G+G  +G+  G G   G G GFGG
Sbjct: 571 GYGGGSGSRGGSGGSHGGGSGFGG 594



 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 24/80 (30%), Positives = 38/80 (47%)

Query: 10  GTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGT 69
           G SG +       GG+GG   +   +G ++   + +  G+ G +GG    G   G+G G 
Sbjct: 491 GGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGH 550

Query: 70  TTGTSTGLGTGLGTGLGFGG 89
           + G+    G G G+G G GG
Sbjct: 551 SGGSGGNYGGGSGSGGGSGG 570



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 36/118 (30%), Positives = 48/118 (40%), Gaps = 4/118 (3%)

Query: 4   NFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG- 62
           +FG   G       +A+  GG  GFG  S   G A      ++ G  G FGG    GFG 
Sbjct: 68  SFGYSYGGGSGGGFSASSLGG--GFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGG 125

Query: 63  -FGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLIN 119
            +G+GFG   G   G G G G  L     +T Q+  + L     +       +N L N
Sbjct: 126 GYGSGFGGFGGFGGGAGGGDGGILTANEKSTMQELNSRLASYLDKVQALEEANNDLEN 183



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           SG S    +     G +GG G+     G  +   + +  G+ G +GG    G G G G+G
Sbjct: 481 SGGSYGRGSRGGSGGSYGGGGS-----GGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYG 535

Query: 69  TTTGTSTGLGTGLGTGLGFGG 89
             +G     G+G G   G GG
Sbjct: 536 GGSGGGHSGGSGGGHSGGSGG 556



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 3/97 (3%)

Query: 6   GAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGT 65
           G+  G SG+   +    GG  G G +  + G     S     G +G  GG+   G G+G 
Sbjct: 518 GSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGS---GGGYGG 574

Query: 66  GFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGG 102
           G G+  G+    G G G G   GG     ++ +  GG
Sbjct: 575 GSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGG 611



 Score = 35.8 bits (81), Expect = 0.094
 Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 11/70 (15%)

Query: 24  GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTST----GLGT 79
           G GG G      GS  S+   +  G+ G +GG  + G G+G G G+  G+      G G+
Sbjct: 474 GLGGRG------GSGGSYGRGSRGGSGGSYGGGGSGG-GYGGGSGSRGGSGGSYGGGSGS 526

Query: 80  GLGTGLGFGG 89
           G G+G G+GG
Sbjct: 527 GGGSGGGYGG 536



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 3/78 (3%)

Query: 11  TSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTT 70
           +SG         GG GG     +  GS  S+      G+ G +GG      G G  +G  
Sbjct: 467 SSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYG---GGGSGGGYGGGSGSRGGSGGSYGGG 523

Query: 71  TGTSTGLGTGLGTGLGFG 88
           +G+  G G G G G G G
Sbjct: 524 SGSGGGSGGGYGGGSGGG 541



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 24/85 (28%), Positives = 37/85 (43%), Gaps = 3/85 (3%)

Query: 5   FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           +G  SG   +  +    +GG GG     + +G          +G+ G  GG+   G GFG
Sbjct: 534 YGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFG 593

Query: 65  TGFGTTTGTSTGLGTGLGTGLGFGG 89
              G + G+  G     G+G G+GG
Sbjct: 594 ---GESGGSYGGGEEASGSGGGYGG 615



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 27/76 (35%), Positives = 33/76 (43%), Gaps = 9/76 (11%)

Query: 23 GGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG----FGTGFGTTTGTSTGLG 78
          GG GG G+  +   S   FS+    G  G F  +   G G     G G G + G S G G
Sbjct: 17 GGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGG 76

Query: 79 TGLG-----TGLGFGG 89
          +G G      G GFGG
Sbjct: 77 SGGGFSASSLGGGFGG 92


>gi|192807292 keratin 24 [Homo sapiens]
          Length = 525

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 34/101 (33%), Positives = 49/101 (48%), Gaps = 10/101 (9%)

Query: 6   GAPSGTSGTAAATAAPAGGFGG-FGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           G  S  S +  ++ A  G FGG FG+ S   G   +  + T  G    FGG    GFG G
Sbjct: 45  GGASSCSLSGGSSGAFGGSFGGGFGSCSVGGGFGGASGSGTGFGGGSSFGGV--SGFGRG 102

Query: 65  TGFGTTTGTSTG-------LGTGLGTGLGFGGFNTQQQQQT 98
           +GF  ++  S+G        G G+G G+G GG  +  ++QT
Sbjct: 103 SGFCGSSRFSSGATGGFYSYGGGMGGGVGDGGLFSGGEKQT 143



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 34/111 (30%), Positives = 49/111 (44%), Gaps = 13/111 (11%)

Query: 6   GAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG--- 62
           G  S    +A  ++  +G   G G +S       + S   + G++G FGG+   GFG   
Sbjct: 13  GGSSSARVSAGGSSFSSGSRCGLGGSSAQGFRGGASSCSLSGGSSGAFGGSFGGGFGSCS 72

Query: 63  FGTGFGTTTGTSTGLG--------TGLGTGLGFGGFNTQQQQQTTLGGLFS 105
            G GFG  +G+ TG G        +G G G GF G +      T  GG +S
Sbjct: 73  VGGGFGGASGSGTGFGGGSSFGGVSGFGRGSGFCGSSRFSSGAT--GGFYS 121


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 33/92 (35%), Positives = 39/92 (42%), Gaps = 16/92 (17%)

Query: 10  GTSGTAAATAAPAGGFGGFGTTS------------TTAGSAFSFSAPTNTGTTGLFGGTQ 57
           G  G    + A A G GG+G+ S            +T+G +F        G    FGG  
Sbjct: 42  GGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGA 101

Query: 58  NKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGG 89
             GFGFG G     G   GLG G G G GFGG
Sbjct: 102 GSGFGFGGG----AGGGFGLGGGAGFGGGFGG 129



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 30/85 (35%), Positives = 36/85 (42%), Gaps = 17/85 (20%)

Query: 5   FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           +G+ SG  G         GG GG G    ++GS +S S+    G  GL GG    G GF 
Sbjct: 502 YGSGSGYGGGLGGGLG--GGLGG-GLAGGSSGSYYSSSS----GGVGLGGGLSVGGSGF- 553

Query: 65  TGFGTTTGTSTGLGTGLGTGLGFGG 89
                    S   G GLG G G GG
Sbjct: 554 ---------SASSGRGLGVGFGSGG 569



 Score = 30.0 bits (66), Expect = 5.2
 Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 6/59 (10%)

Query: 37  SAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTG------TSTGLGTGLGTGLGFGG 89
           S  + S  +  G+   +GG    G G G G G   G      +S+  G GLG GL  GG
Sbjct: 492 SVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGG 550


>gi|150378545 POM121 membrane glycoprotein (rat)-like [Homo sapiens]
          Length = 987

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 32/91 (35%), Positives = 44/91 (48%), Gaps = 6/91 (6%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGF 61
           AF+FGA  G SG+ A +    GG G     +T   + F+F+  + T +  +FGGT    F
Sbjct: 864 AFSFGA--GQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPTF 921

Query: 62  GFGT---GFGTTTGTSTGLGTGLGTGLGFGG 89
           G  T   G G T+G+S   G       GF G
Sbjct: 922 GQNTPAPGVG-TSGSSLSFGASSAPAQGFVG 951



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 43/151 (28%), Positives = 62/151 (41%), Gaps = 22/151 (14%)

Query: 3   FNFGAPSGTS-GTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNK-- 59
           F+FGA + +  G    TA+       FG+T+ +  +    +AP  +G+ G+   T     
Sbjct: 801 FSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGGSAAPAGSGSFGINVATPGSSA 860

Query: 60  ---GFGFGTGFGTTTGTSTGLGTGLG-TGLGFGGFNT--------QQQQQTTLGG----L 103
               F FG G   +T TST    GLG   LG  G +T          + +   GG     
Sbjct: 861 TTGAFSFGAGQSGSTATSTPFTGGLGQNALGTTGQSTPFAFNVGSTTESKPVFGGTATPT 920

Query: 104 FSQPTQAP---TQSNQLINTASALSAPTLLG 131
           F Q T AP   T  + L   AS+  A   +G
Sbjct: 921 FGQNTPAPGVGTSGSSLSFGASSAPAQGFVG 951



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 31/111 (27%), Positives = 46/111 (41%), Gaps = 23/111 (20%)

Query: 2   AFNFGAPSGTSGTAAATAAPAGG---------------FGG-----FGTTST-TAGSAFS 40
           +F FG  +  +   A T APA                 FGG     FG  +T +A  A +
Sbjct: 729 SFTFGNSAAPAPATAPTPAPASTIKIVPAHVPTPIQPTFGGATHSAFGLKATASAFGAPA 788

Query: 41  FSAPTNTGTTGLF--GGTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGG 89
            S P   G+T +F  G   + GFG  T   ++  +S+  G+   +   FGG
Sbjct: 789 SSQPAFGGSTAVFSFGAATSSGFGATTQTASSGSSSSVFGSTTPSPFTFGG 839


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 30/83 (36%), Positives = 39/83 (46%), Gaps = 5/83 (6%)

Query: 10  GTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNK-GF--GFGTG 66
           G  G A    + AG FG     +  +  + S S    +   G FGG ++  GF  G+G G
Sbjct: 38  GAGGGACGFRSGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGG 97

Query: 67  FGTTTGTSTGLGTGLGTGLGFGG 89
           FG + G   G G G G G GFGG
Sbjct: 98  FGGSYGG--GFGGGRGVGSGFGG 118



 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 33/87 (37%), Positives = 43/87 (49%), Gaps = 15/87 (17%)

Query: 3   FNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG 62
           +N G+    S + AA ++ AGGFGG  ++   AG           G  G FGG+   GFG
Sbjct: 59  YNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAG-----------GYGGGFGGSYGGGFG 107

Query: 63  FGTGFGTTTGTSTGLGTGLGTGLGFGG 89
            G G G+  G + G G   G G GFGG
Sbjct: 108 GGRGVGSGFGGAGGFG---GAG-GFGG 130



 Score = 35.8 bits (81), Expect = 0.094
 Identities = 26/94 (27%), Positives = 47/94 (50%), Gaps = 14/94 (14%)

Query: 32  STTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFN 91
           ++T+GS+ S        + G+FGG    G G   G G+++ +S+G G   G+G G+GG +
Sbjct: 513 TSTSGSSGS--------SRGVFGGVSGSGSGGYKG-GSSSSSSSGYGVSGGSGSGYGGVS 563

Query: 92  TQQQQQTTLGGLFSQPTQAPTQSNQLINTASALS 125
           +      + GG  S  +   + S   +  A ++S
Sbjct: 564 S-----GSTGGRGSSGSYQSSSSGSRLGGAGSIS 592



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 19/94 (20%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           + TSG++ ++    GG  G G+     GS  S S+ +  G +G          G G+G+G
Sbjct: 513 TSTSGSSGSSRGVFGGVSGSGSGGYKGGS--SSSSSSGYGVSG----------GSGSGYG 560

Query: 69  TTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGG 102
             +  STG       G G  G        + LGG
Sbjct: 561 GVSSGSTG-------GRGSSGSYQSSSSGSRLGG 587



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 42/146 (28%), Positives = 53/146 (36%), Gaps = 13/146 (8%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           +G  G   ++   AGG+GG    S   G        +  G  G FGG    GFG G G  
Sbjct: 78  AGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGA--GGFG-GPGVF 134

Query: 69  TTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGL----FSQPTQAPTQSNQLINT---- 120
              G+  G G G G G   GG       Q+ L  L      Q  Q   Q  + I T    
Sbjct: 135 GGPGSFGGPG-GFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNK 193

Query: 121 -ASALSAPTLLGDERDAILAKWNQLQ 145
            AS +     L  +   +  KW  LQ
Sbjct: 194 FASFIDKVRFLEQQNKVLETKWELLQ 219



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 29/126 (23%), Positives = 57/126 (45%), Gaps = 14/126 (11%)

Query: 4   NFGAPSGTSGTA-----AATAAPAGGFGGFGTTSTT--------AGSAFSFSAPTNTGTT 50
           N  + SG+SG++       + + +GG+ G  ++S++        +GS +   +  +TG  
Sbjct: 511 NVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGR 570

Query: 51  GLFGGTQNKGFGFGT-GFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQ 109
           G  G  Q+   G    G G+ + + +G+G+  G+    GG   +     +    FSQ T 
Sbjct: 571 GSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTS 630

Query: 110 APTQSN 115
           +   S+
Sbjct: 631 SSQHSS 636


>gi|131412228 keratin 13 isoform b [Homo sapiens]
          Length = 420

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 16 AATAAPAGGFGGFGTTSTTAGSAFSFSAP--TNTGTTGLFGGTQNKGFGFGTGFGTTTGT 73
          +++A+  GGFGG G+     G   S  +    + G+ G +GG  + GFG G G G   G 
Sbjct: 7  SSSASYGGGFGG-GSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGY 65

Query: 74 STGLGTGLGTGLGFGGF 90
            GLG G G GLG GGF
Sbjct: 66 GGGLGGGYGGGLG-GGF 81



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 21/85 (24%)

Query: 6  GAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGT 65
          G    T  T   +   AGG+GG                    G +  FGG    GFG G 
Sbjct: 26 GRGVSTCSTRFVSGGSAGGYGG--------------------GVSCGFGGGAGSGFGGGY 65

Query: 66 GFGTTTGTSTGLGTGLGTGLGFGGF 90
          G G   G   GLG G G G   GGF
Sbjct: 66 GGGLGGGYGGGLGGGFGGGFA-GGF 89


>gi|131412225 keratin 13 isoform a [Homo sapiens]
          Length = 458

 Score = 45.8 bits (107), Expect = 9e-05
 Identities = 31/77 (40%), Positives = 41/77 (53%), Gaps = 4/77 (5%)

Query: 16 AATAAPAGGFGGFGTTSTTAGSAFSFSAP--TNTGTTGLFGGTQNKGFGFGTGFGTTTGT 73
          +++A+  GGFGG G+     G   S  +    + G+ G +GG  + GFG G G G   G 
Sbjct: 7  SSSASYGGGFGG-GSCQLGGGRGVSTCSTRFVSGGSAGGYGGGVSCGFGGGAGSGFGGGY 65

Query: 74 STGLGTGLGTGLGFGGF 90
            GLG G G GLG GGF
Sbjct: 66 GGGLGGGYGGGLG-GGF 81



 Score = 36.6 bits (83), Expect = 0.055
 Identities = 28/85 (32%), Positives = 31/85 (36%), Gaps = 21/85 (24%)

Query: 6  GAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGT 65
          G    T  T   +   AGG+GG                    G +  FGG    GFG G 
Sbjct: 26 GRGVSTCSTRFVSGGSAGGYGG--------------------GVSCGFGGGAGSGFGGGY 65

Query: 66 GFGTTTGTSTGLGTGLGTGLGFGGF 90
          G G   G   GLG G G G   GGF
Sbjct: 66 GGGLGGGYGGGLGGGFGGGFA-GGF 89


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 46/222 (20%), Positives = 95/222 (42%), Gaps = 2/222 (0%)

Query: 266 EQANIKTQLQQLGVTLSMTRTELSPAQIKQLLQNPPAGVDPIIWEQAKVDNPDSEKLIPV 325
           E+  +KTQL      +   R EL+    K+ LQ              K    D E  +  
Sbjct: 524 EKDELKTQLYAALQQIENLRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKN 583

Query: 326 PMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISELQKNQTTSVAKIAQYKRKLMDLSHR 385
            +     L   LK Q ++  Q +     + E+I+EL+K+Q    AK+ + +  + DLS  
Sbjct: 584 SLDTIHRLESELKKQSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAI 643

Query: 386 TLQVLIKQEIQRKSGYAIQADEEQLRVQLDTIQGELNAPTQFKGRLNELMSQIRMQNHFG 445
              +  K   + ++  A+  D   L  Q  + + E  A    + +L   + Q  +++   
Sbjct: 644 RADLANKLAEEERAKKAVLKDLSDLTAQAKS-RDEETATIITQLKLERDVHQRELKDLTS 702

Query: 446 AVRSEERYYIDADLLREIKQHLKQQQEGLSHLISIIKDDLED 487
           +++S +  + + ++   +K   K++ E  +H+ ++  + LE+
Sbjct: 703 SLQSVKTKH-EQNIQELMKHFKKEKSEAENHIRTLKAESLEE 743


>gi|33946327 nucleoporin 214kDa [Homo sapiens]
          Length = 2090

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 34/104 (32%), Positives = 45/104 (43%), Gaps = 15/104 (14%)

Query: 5    FGAPSGTSGTAAATAAPA---------GGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGG 55
            FG   G  G  A  +APA         G   G GT + +AG  F F + +NT + G    
Sbjct: 1982 FGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGG-FGFGSSSNTTSFGTLAS 2040

Query: 56   TQNKGFGF----GTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQ 95
                 FG      +GFGT +   +G G+G G G  FG  N+  Q
Sbjct: 2041 QNAPTFGSLSQQTSGFGTQSSGFSGFGSGTG-GFSFGSNNSSVQ 2083



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 37/98 (37%), Positives = 53/98 (54%), Gaps = 17/98 (17%)

Query: 5    FGAPSGTSGTAA----ATAAPAGGFGGFGTTSTTA--GSAFSFSAPT----NTGTTGLFG 54
            F +P G++G         AA AGGFG FG++S T   G+  S +APT    +  T+G   
Sbjct: 2000 FTSPLGSTGGKVFGEGTAAASAGGFG-FGSSSNTTSFGTLASQNAPTFGSLSQQTSGF-- 2056

Query: 55   GTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFGGFNT 92
            GTQ+ GF   +GFG+ TG     G+   +  GFGG+ +
Sbjct: 2057 GTQSSGF---SGFGSGTG-GFSFGSNNSSVQGFGGWRS 2090



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 36/123 (29%), Positives = 56/123 (45%), Gaps = 19/123 (15%)

Query: 5    FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
            FG P+ ++ T+ + +     FG    +ST++ S+FSF   +     GLFG +    FG  
Sbjct: 1756 FGQPASSTPTSTSGSV----FGA--ASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQS 1809

Query: 65   TGF--------GTTTGTSTGLGTGLG--TGLGFGGFNTQQ---QQQTTLGGLFSQPTQAP 111
             GF        GT+  T+T   +G       GFG  NT     Q  +T G +F Q + + 
Sbjct: 1810 PGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSS 1869

Query: 112  TQS 114
            + S
Sbjct: 1870 SGS 1872



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 23/176 (13%)

Query: 3    FNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFG-GTQNKGF 61
            F+F  P  +S        PA G     T ++T+GS F  ++ T++ ++  FG  + N G 
Sbjct: 1743 FSFSQPGFSS-------VPAFGQPASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGG 1795

Query: 62   G-FGTGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINT 120
            G FG       G S G G G   G  FGG +       T G  F Q +   + +   +  
Sbjct: 1796 GLFGQSNAPAFGQSPGFGQG---GSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFG 1852

Query: 121  ASALSAPTLLGDERD----AILAKWNQLQAFWGTGKGYFN--NNIPPVEFTQENPF 170
             +A +   + G +      ++    N      G G G+F+     P  +   +NPF
Sbjct: 1853 QAASTGGIVFGQQSSSSSGSVFGSGNT-----GRGGGFFSGLGGKPSQDAANKNPF 1903



 Score = 37.7 bits (86), Expect = 0.025
 Identities = 39/127 (30%), Positives = 52/127 (40%), Gaps = 29/127 (22%)

Query: 3    FNFGAPSGTSGTAAATAAPA----GGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFG---- 54
            F F +P+ T G  AA    +    GG  GFG      GSA +F++P  +    +FG    
Sbjct: 1959 FGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAF-GSAPAFTSPLGSTGGKVFGEGTA 2017

Query: 55   GTQNKGFGFG-----TGFGT-------TTGTSTGLGTGLGT--------GLGFGGFNTQQ 94
                 GFGFG     T FGT       T G+ +   +G GT        G G GGF+   
Sbjct: 2018 AASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGS 2077

Query: 95   QQQTTLG 101
               +  G
Sbjct: 2078 NNSSVQG 2084



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 42/177 (23%), Positives = 69/177 (38%), Gaps = 29/177 (16%)

Query: 6    GAPSGTSGTAAATAAPAGGFGGFGTTSTT--------------AGSAFSFSAPTNTGTTG 51
            G PS  +      ++ +GGFG   T++T+              A S+F    PT T ++G
Sbjct: 1891 GKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSG 1950

Query: 52   LFGGTQNKGFGFGT-----GFGTTTGTSTGLGTGLGTGLGFGG---FNTQQQQQTTLGG- 102
              G   ++GFGF +     GFG       G     G   GFGG   F +     + LG  
Sbjct: 1951 -GGSVASQGFGFSSPNKTGGFG--AAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGST 2007

Query: 103  ---LFSQPTQAPTQSNQLINTASALSAPTLLGDERDAILAKWNQLQAFWGTGKGYFN 156
               +F + T A +       ++S  ++   L  +        +Q  + +GT    F+
Sbjct: 2008 GGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTFGSLSQQTSGFGTQSSGFS 2064


>gi|56788377 nucleoporin like 1 isoform b [Homo sapiens]
          Length = 587

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 47/146 (32%), Positives = 59/146 (40%), Gaps = 29/146 (19%)

Query: 3   FNFGAPSGTSGTAAATAAPAGG-----------------FGGFGTTSTTAGSAFSFSAPT 45
           F+FG+ +  S T AA     GG                 FG  G+TST A +    SAP+
Sbjct: 5   FSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATT----SAPS 60

Query: 46  NTGTTGLFGGTQNKGFGFGTGFGTTTGTSTGLGTGLGTGLGFG-GFNTQQQQQTTLG-GL 103
           +   TGLFG     GF  G   GT TGT     T      GF  GFN      T     +
Sbjct: 61  SGFGTGLFGSKPATGFTLG---GTNTGTP---ATTSAATTGFSLGFNKPAASATPFALPI 114

Query: 104 FSQPTQAPTQSNQLINTASALSAPTL 129
            S      T S+ L +T +A +  TL
Sbjct: 115 TSTSASGLTLSSALTSTPAASTGFTL 140



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 35/116 (30%), Positives = 45/116 (38%), Gaps = 19/116 (16%)

Query: 27  GFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG---------TTTGTSTGL 77
           GF   S T GS    +  T+TG    FG   +     G  FG         TT+  S+G 
Sbjct: 4   GFSFGSGTLGSTTVAAGGTSTGGVFSFGTGASSNPSVGLNFGNLGSTSTPATTSAPSSGF 63

Query: 78  GTGL-----GTGLGFGGFNTQQQQQTTLGGL-----FSQPTQAPTQSNQLINTASA 123
           GTGL      TG   GG NT     T+         F++P  + T     I + SA
Sbjct: 64  GTGLFGSKPATGFTLGGTNTGTPATTSAATTGFSLGFNKPAASATPFALPITSTSA 119



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 26/65 (40%), Positives = 34/65 (52%), Gaps = 13/65 (20%)

Query: 3   FNFGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGL-FGGTQNKGF 61
           F FG  +  SG+ +A         GFG++ST   S F+FS P  T + GL FG +     
Sbjct: 517 FGFGTTNKPSGSLSA---------GFGSSST---SGFNFSNPGITASAGLTFGVSNPASA 564

Query: 62  GFGTG 66
           GFGTG
Sbjct: 565 GFGTG 569



 Score = 33.1 bits (74), Expect = 0.61
 Identities = 34/121 (28%), Positives = 50/121 (41%), Gaps = 20/121 (16%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           SG + ++A T+ PA       +T  T  +    +A T T +TGL  G    G G      
Sbjct: 120 SGLTLSSALTSTPAA------STGFTLNNLGGTTATTTTASTGLSLGGALAGLGGSLFQS 173

Query: 69  TTTGTS----TGLGTGLGT----------GLGFGGFNTQQQQQTTLGGLFSQPTQAPTQS 114
           T TGTS      LG  LGT          GLG   F++   +++   G   + ++A    
Sbjct: 174 TNTGTSGLGQNALGLTLGTTAATSTAGNEGLGGIDFSSSSDKKSDKTGTRPEDSKALKDE 233

Query: 115 N 115
           N
Sbjct: 234 N 234



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 37/114 (32%), Positives = 45/114 (39%), Gaps = 19/114 (16%)

Query: 8   PSGTSGTAAATAAPAG-------GFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKG 60
           P  T   AAA A  A          G   +   + G+ F     T   ++GL G +   G
Sbjct: 442 PFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGSGIGTGLQSSGL-GSSNLGG 500

Query: 61  FGFGTGFG-TTTGTST-GLGT------GLGTGLG---FGGFNTQQQQQTTLGGL 103
           FG  +GFG +TTG ST G GT       L  G G     GFN      T   GL
Sbjct: 501 FGTSSGFGCSTTGASTFGFGTTNKPSGSLSAGFGSSSTSGFNFSNPGITASAGL 554


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 70/354 (19%), Positives = 139/354 (39%), Gaps = 49/354 (13%)

Query: 197  KKETEIRSQQQQLVESLHKVLGGNQTLTVNVEGTKTLPDDQTEVVIYVVERSPNGTSRRV 256
            K+E  +  + ++L E   +++ G +TL+       +     T+V   + ER  +   + +
Sbjct: 1958 KEEKALNLEMKRLAEEKMRLVEGKETLSKGETPETSRQRKMTQVEQELFERKLSLEEKIL 2017

Query: 257  PATTLYAHFEQANIK------TQLQQLGVTLSMTRTELSPAQIK--QLLQNPPAGVDPII 308
                     E++ I       T+ Q++ V       + S   IK  + L   PA ++ I+
Sbjct: 2018 LHEDRILAMEESEIAKGKLEFTRGQRIFVQGQRKLAKASRKLIKKRESLSKEPAKLNKIL 2077

Query: 309  WEQAKVDNPDSEKLIPVPMVGFKELLRRLKVQDQMTKQHQTRLDIISEDISELQKNQTTS 368
                K+     E+ +    +   ++ R L V+++     Q++LDI   D SE +   T  
Sbjct: 2078 KALQKLTR--DERKLTQEEIKMTKMKRALFVKERRLSIEQSKLDIKEWDFSEKRSELTKD 2135

Query: 369  VAKIAQYKRKLMDLSHRTLQVLIK-----QEIQRKSGYAIQADEEQ-------------- 409
              K+A+ +RKL +   R +    K      ++ RK    I  DEE+              
Sbjct: 2136 EKKLARKQRKLANKMRRMINKEEKMTEEESKLARKHSEVILDDEEEGGIEEEEVIPFLKR 2195

Query: 410  -----------------LRVQLDTIQGELNAPTQFKGRLNELMSQIRMQNHFGAVRSEER 452
                                Q+D ++ E +   + +  L+EL  Q  + +     R EE 
Sbjct: 2196 RWRKRKEAKRGDKPKEKFSSQVDEVESEEHFSEEMESLLDELEKQESLSSEEEEEREEEE 2255

Query: 453  YYIDADLLREIKQHLKQQQEGLSHLISIIKDDLEDIKLVEHGLNETIHIRGGVF 506
               + + +RE ++  K+++EG    +   K++ E  K  +    E +  +  VF
Sbjct: 2256 ER-EEEEVREEEEERKEEEEGEEKQVE--KEEEEKKKKKKEKKKEEVQEKEEVF 2306


>gi|24430190 keratin 15 [Homo sapiens]
          Length = 456

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 34/84 (40%), Positives = 43/84 (51%), Gaps = 7/84 (8%)

Query: 10 GTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPT----NTGTTGLFGGTQNKGFGFGT 65
          G S    +  A  GGFGG G+ S   GS  S SA +    ++G+ G +GG   +  GFG 
Sbjct: 15 GGSTRGGSLLAGGGGFGG-GSLSGGGGSR-SISASSARFVSSGSGGGYGGGM-RVCGFGG 71

Query: 66 GFGTTTGTSTGLGTGLGTGLGFGG 89
          G G+  G   G G G G G GFGG
Sbjct: 72 GAGSVFGGGFGGGVGGGFGGGFGG 95


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 47/158 (29%), Positives = 60/158 (37%), Gaps = 18/158 (11%)

Query: 5   FGAPS--GTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFG 62
           FG+ S  G  GT + + + AGG GGFG      G    F   ++ G    F G    G G
Sbjct: 58  FGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGG 117

Query: 63  FG----TGFGTTTGTSTGLG--TGLGTGLGFGGFNTQQQQQTTLGGL----FSQPTQAPT 112
           FG     GFG   G   GLG   G G G   GG +     Q+ L  L      +      
Sbjct: 118 FGGGRFGGFGGPGGVG-GLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKA 176

Query: 113 QSNQLINT-----ASALSAPTLLGDERDAILAKWNQLQ 145
           Q  + I T     AS +     L  +   +  KW  LQ
Sbjct: 177 QEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQ 214



 Score = 37.4 bits (85), Expect = 0.032
 Identities = 32/76 (42%), Positives = 36/76 (47%), Gaps = 8/76 (10%)

Query: 23  GGFGG--FGTTSTTA---GSAFSFSAPTNTGTTGLFGGTQNKGFGFGTG--FGTTTGTST 75
           GGFGG  FG+ S        + S S     G  G  GG   +G GFG G  FG  +G S 
Sbjct: 51  GGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSG 110

Query: 76  GLGTGLGTGLG-FGGF 90
           G   G G G G FGGF
Sbjct: 111 GGFGGGGFGGGRFGGF 126



 Score = 37.0 bits (84), Expect = 0.042
 Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 3/97 (3%)

Query: 9   SGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           S T  +  A+ A  GG GG G++S    S+ S S  +    +G  GG+   G   G G+G
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYG 564

Query: 69  TTTGTSTGLGTGLGT---GLGFGGFNTQQQQQTTLGG 102
           +  G+    G+G G+    +  GG+ +   + ++ GG
Sbjct: 565 SGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGG 601


>gi|239752328 PREDICTED: hypothetical protein XP_002348200 [Homo
          sapiens]
          Length = 174

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 14/78 (17%)

Query: 11 TSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTT 70
          T+GT AAT A        GT+ST A      S      + G  G +     G GTG GT 
Sbjct: 18 TTGTRAATGA--------GTSSTKA------SEEPKCESGGQAGTSTEATTGAGTGTGTV 63

Query: 71 TGTSTGLGTGLGTGLGFG 88
           GT TG   G  T LGFG
Sbjct: 64 IGTGTGTSAGTATLLGFG 81


>gi|239746841 PREDICTED: hypothetical protein XP_002344236 [Homo
          sapiens]
          Length = 174

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/78 (39%), Positives = 35/78 (44%), Gaps = 14/78 (17%)

Query: 11 TSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFGTT 70
          T+GT AAT A        GT+ST A      S      + G  G +     G GTG GT 
Sbjct: 18 TTGTRAATGA--------GTSSTKA------SEEPKCESGGQAGTSTEATTGAGTGTGTV 63

Query: 71 TGTSTGLGTGLGTGLGFG 88
           GT TG   G  T LGFG
Sbjct: 64 IGTGTGTSAGTATLLGFG 81


>gi|6679074 nucleoporin like 2 [Homo sapiens]
          Length = 423

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 12/80 (15%)

Query: 19  AAPAGGFG----------GFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFGTGFG 68
           AAPA GFG          GF   ++++ +A +FS  TN+G      G+   GFG    FG
Sbjct: 214 AAPAFGFGSSQAATFMSPGFPVNNSSSDNAQNFSFKTNSGFAAASSGSP-AGFGSSPAFG 272

Query: 69  TTTGTSTGLGTGLGTGLGFG 88
               TS+G+ T      GFG
Sbjct: 273 AAASTSSGISTS-APAFGFG 291



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 36/128 (28%), Positives = 56/128 (43%), Gaps = 15/128 (11%)

Query: 5   FGAPSGTSGTAAATAAPAGGFGGFGTTSTTAGSAFSFSAPTNTGTTGLFGGTQNKGFGFG 64
           FGA + TS +  +T+APA GFG       T+ ++FSF +P  +     FG   + GF   
Sbjct: 271 FGAAASTS-SGISTSAPAFGFG---KPEVTSAASFSFKSPAASS----FG---SPGFSGL 319

Query: 65  TGFGTTTGTSTGLGTGLGTGLGFGGFNTQQQQQTTLGGLFSQPTQAPTQSNQLINTASAL 124
                T      +    G G    GF +      T    FS+P+ + T  N  I+T+ + 
Sbjct: 320 PASLATGPVRAPVAPAFGGGSSVAGFGSPGSHSHT---AFSKPS-SDTFGNSSISTSLSA 375

Query: 125 SAPTLLGD 132
           S+  +  D
Sbjct: 376 SSSIIATD 383


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.132    0.373 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,642,474
Number of Sequences: 37866
Number of extensions: 879539
Number of successful extensions: 5418
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 80
Number of HSP's successfully gapped in prelim test: 182
Number of HSP's that attempted gapping in prelim test: 3472
Number of HSP's gapped (non-prelim): 1157
length of query: 507
length of database: 18,247,518
effective HSP length: 107
effective length of query: 400
effective length of database: 14,195,856
effective search space: 5678342400
effective search space used: 5678342400
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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