Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 122056614
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
(617 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens] 1285 0.0
gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens] 1085 0.0
gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens] 498 e-141
gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens] 427 e-119
gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens] 417 e-116
gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens] 348 1e-95
gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens] 297 2e-80
gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens] 291 2e-78
gi|109638745 transforming growth factor beta 1 induced transcrip... 172 8e-43
gi|21361591 transforming growth factor beta 1 induced transcript... 172 1e-42
gi|170932518 paxillin isoform 3 [Homo sapiens] 161 1e-39
gi|170932516 paxillin isoform 2 [Homo sapiens] 161 1e-39
gi|221316659 leupaxin isoform 1 [Homo sapiens] 159 9e-39
gi|4758670 leupaxin isoform 2 [Homo sapiens] 159 9e-39
gi|170932514 paxillin isoform 1 [Homo sapiens] 155 1e-37
gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens] 140 5e-33
gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens] 134 2e-31
gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens] 131 2e-30
gi|13994151 PDZ and LIM domain 1 [Homo sapiens] 129 1e-29
gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens] 122 7e-28
gi|54112385 four and a half LIM domains 3 [Homo sapiens] 119 8e-27
gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens] 117 3e-26
gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens] 113 5e-25
gi|87159836 four and a half LIM domains 2 [Homo sapiens] 112 1e-24
gi|87159834 four and a half LIM domains 2 [Homo sapiens] 112 1e-24
gi|42403575 four and a half LIM domains 2 [Homo sapiens] 112 1e-24
gi|87159832 four and a half LIM domains 2 [Homo sapiens] 112 1e-24
gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens] 112 1e-24
gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens] 112 1e-24
gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens] 112 1e-24
>gi|122056614 LIM domain binding 3 isoform 2 [Homo sapiens]
Length = 617
Score = 1285 bits (3325), Expect = 0.0
Identities = 617/617 (100%), Positives = 617/617 (100%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120
Query: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180
RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD
Sbjct: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180
Query: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 240
FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 240
Query: 241 QDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP 300
QDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP
Sbjct: 241 QDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQP 300
Query: 301 VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN 360
VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN
Sbjct: 301 VPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN 360
Query: 361 PAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPP 420
PAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPP
Sbjct: 361 PAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPP 420
Query: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFV 480
LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFV
Sbjct: 421 LARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFV 480
Query: 481 EEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHM 540
EEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHM
Sbjct: 481 EEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHM 540
Query: 541 EDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFY 600
EDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFY
Sbjct: 541 EDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFY 600
Query: 601 SKKDRPLCKKHAHTINL 617
SKKDRPLCKKHAHTINL
Sbjct: 601 SKKDRPLCKKHAHTINL 617
>gi|45592959 LIM domain binding 3 isoform 1 [Homo sapiens]
Length = 727
Score = 1085 bits (2805), Expect = 0.0
Identities = 555/728 (76%), Positives = 572/728 (78%), Gaps = 112/728 (15%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK------------- 107
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 108 -------VVVNSPANADYQERFNPSALKDSALSTHKPIEVKG------------------ 142
+P + + F+P+ + SA S+ G
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 143 LGGKA---TIIHAQYNTPISMYSQDAIMD-------AIAGQAQAQGSDFSGSLPIKDLAV 192
LG KA + QYN PI +YS + + + ++ G+A G GSLPIKDLAV
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLP-GGSLPIKDLAV 239
Query: 193 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS- 251
DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRS
Sbjct: 240 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSS 299
Query: 252 ----------------------------RPQASSYSPAVAAS------------------ 265
P A+S A AA+
Sbjct: 300 TPIEHAPVCTSQATTPLLPASAQPPAAASPSAASPPLATAAAHTAIASASTTAPASSPAD 359
Query: 266 ----------------SAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPS 309
SAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPS
Sbjct: 360 SPRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPS 419
Query: 310 PGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSG 369
PGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSG
Sbjct: 420 PGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSG 479
Query: 370 GPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRA 429
GPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRA
Sbjct: 480 GPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRA 539
Query: 430 ERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489
ERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE
Sbjct: 540 ERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 599
Query: 490 RCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEK 549
RCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEK
Sbjct: 600 RCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEK 659
Query: 550 DYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
DYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK
Sbjct: 660 DYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 719
Query: 610 KHAHTINL 617
KHAHTINL
Sbjct: 720 KHAHTINL 727
>gi|122056619 LIM domain binding 3 isoform 4 [Homo sapiens]
Length = 283
Score = 498 bits (1281), Expect = e-141
Identities = 252/252 (100%), Positives = 252/252 (100%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120
Query: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180
RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD
Sbjct: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180
Query: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 240
FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM
Sbjct: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFM 240
Query: 241 QDPDEEALRRSR 252
QDPDEEALRRSR
Sbjct: 241 QDPDEEALRRSR 252
>gi|197383077 PDZ and LIM domain 5 isoform a [Homo sapiens]
Length = 596
Score = 427 bits (1098), Expect = e-119
Identities = 255/669 (38%), Positives = 342/669 (51%), Gaps = 130/669 (19%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSK-----RPIPISTTAPP-VQTPLPVIPHQKVVVNSPAN 115
HLEAQNKIK + +L++TLQ++ P+P+ P V P+P+ V S N
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRASAAPKPEPVPVQKGEPKEVVKPVPITSPAVSKVTSTNN 122
Query: 116 ADYQER---------------------FNPSALKDSALSTHKPIEV-------------- 140
Y + F P+ S+ ++ P+
Sbjct: 123 MAYNKAPRPFGSVSSPKVTSIPSPSSAFTPAHATTSSHASPSPVAAVTPPLFAASGLHAN 182
Query: 141 ---------KGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQ-AQGSDFSGSLPIKDL 190
L T ++ ++ + + GQ + +QG + P +
Sbjct: 183 ANLSADQSPSALSAGKTAVNVPRQPTVTSVCSETSQELAEGQRRGSQGDSKQQNGPPRKH 242
Query: 191 AVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEA 247
V+ + Y S + ++ ++W R+ QSRSFRILAQ+TGT E
Sbjct: 243 IVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGT--------EH 294
Query: 248 LRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYS 307
L+ S A +T + P+P+ + AS R +P S S
Sbjct: 295 LKESE----------------ADNTKKANNSQEPSPQ-LASSVASTRS-----MPESLDS 332
Query: 308 PSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAY 367
P+ G P + + A A+ P + SP P+ PS N S Y
Sbjct: 333 PTSGR---PGVTSLTAAAAFKPVGSTGVIKSP-SWQRPNQG---VPSTGRISN---SATY 382
Query: 368 SGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQ 427
SG A PA + G P VQ
Sbjct: 383 SGSVA------------------------------------PANSALGQTQPSDQDTLVQ 406
Query: 428 RAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVY 487
RAE PA RTP+C HCN VIRGPFLVA+G+SWHPEEF CA+CK ++A + FVEE+ +Y
Sbjct: 407 RAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYIGFVEEKGALY 466
Query: 488 CERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
CE CYE+FFAP C +C KI+GEV+ AL+QTWH +CFVC AC KP N++FH+EDGEPYC
Sbjct: 467 CELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNVFHLEDGEPYC 526
Query: 548 EKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPL 607
E DY LF T CHGC+FP+EAGD F+EALG+TWHDTCF+C+VC +LEGQ F+SKKD+PL
Sbjct: 527 ETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQTFFSKKDKPL 586
Query: 608 CKKHAHTIN 616
CKKHAH++N
Sbjct: 587 CKKHAHSVN 595
>gi|197383100 PDZ and LIM domain 5 isoform b [Homo sapiens]
Length = 487
Score = 417 bits (1072), Expect = e-116
Identities = 249/619 (40%), Positives = 324/619 (52%), Gaps = 139/619 (22%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
HLEAQNKIK + +L++TLQ++ +A P P+PV QK V S + Q
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQ-- 109
Query: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQ-AQGSD 180
+ GQ + +QG
Sbjct: 110 ----------------------------------------------ELAEGQRRGSQGDS 123
Query: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGT 237
+ P + V+ + Y S + ++ ++W R+ QSRSFRILAQ+TGT
Sbjct: 124 KQQNGPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGT 183
Query: 238 EFMQDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSV 297
E L+ S A +T + P+P+ + AS R
Sbjct: 184 --------EHLKESE----------------ADNTKKANNSQEPSPQ-LASSVASTRS-- 216
Query: 298 YQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAP 357
+P S SP+ G P + + A A+ P + SP P+ PS
Sbjct: 217 ---MPESLDSPTSGR---PGVTSLTAAAAFKPVGSTGVIKSP-SWQRPNQG---VPSTGR 266
Query: 358 NYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQ 417
N S YSG A PA + G
Sbjct: 267 ISN---SATYSGSVA------------------------------------PANSALGQT 287
Query: 418 VPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADV 477
P VQRAE PA RTP+C HCN VIRGPFLVA+G+SWHPEEF CA+CK ++A +
Sbjct: 288 QPSDQDTLVQRAEHIPAGKRTPMCAHCNQVIRGPFLVALGKSWHPEEFNCAHCKNTMAYI 347
Query: 478 CFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSL 537
FVEE+ +YCE CYE+FFAP C +C KI+GEV+ AL+QTWH +CFVC AC KP N++
Sbjct: 348 GFVEEKGALYCELCYEKFFAPECGRCQRKILGEVISALKQTWHVSCFVCVACGKPIRNNV 407
Query: 538 FHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQ 597
FH+EDGEPYCE DY LF T CHGC+FP+EAGD F+EALG+TWHDTCF+C+VC +LEGQ
Sbjct: 408 FHLEDGEPYCETDYYALFGTICHGCEFPIEAGDMFLEALGYTWHDTCFVCSVCCESLEGQ 467
Query: 598 PFYSKKDRPLCKKHAHTIN 616
F+SKKD+PLCKKHAH++N
Sbjct: 468 TFFSKKDKPLCKKHAHSVN 486
>gi|122056617 LIM domain binding 3 isoform 3 [Homo sapiens]
Length = 330
Score = 348 bits (892), Expect = 1e-95
Identities = 198/300 (66%), Positives = 213/300 (71%), Gaps = 49/300 (16%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM
Sbjct: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK------------- 107
THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQK
Sbjct: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAP 120
Query: 108 -------VVVNSPANADYQERFNPSALKDSALSTHKPIEVKG------------------ 142
+P + + F+P+ + SA S+ G
Sbjct: 121 SPSPEARASPGTPGTPELRPTFSPAFSRPSAFSSLAEASDPGPPRASLRAKTSPEGARDL 180
Query: 143 LGGKA---TIIHAQYNTPISMYSQDAIMD-------AIAGQAQAQGSDFSGSLPIKDLAV 192
LG KA + QYN PI +YS + + + ++ G+A G GSLPIKDLAV
Sbjct: 181 LGPKALPGSSQPRQYNNPIGLYSAETLREMAQMYQMSLRGKASGVGLP-GGSLPIKDLAV 239
Query: 193 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 252
DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR
Sbjct: 240 DSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 299
Score = 39.3 bits (90), Expect = 0.011
Identities = 30/111 (27%), Positives = 45/111 (40%), Gaps = 6/111 (5%)
Query: 286 RVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTP 345
R + ++ P V P+P + P + + + PSP+P SP TP PT++P
Sbjct: 85 RPIPISTTAPPVQTPLPVIPHQKDPALDTNGSLVAPSPSPEARASPGTPGTPELRPTFSP 144
Query: 346 S-PAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKS 395
+ P+ S A +P P A + A P D K PG S
Sbjct: 145 AFSRPSAFSSLAEASDPGPPRA-----SLRAKTSPEGARDLLGPKALPGSS 190
>gi|42741675 PDZ and LIM domain 7 isoform 2 [Homo sapiens]
Length = 423
Score = 297 bits (761), Expect = 2e-80
Identities = 163/408 (39%), Positives = 209/408 (51%), Gaps = 98/408 (24%)
Query: 205 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSRPQASSYSPAVAA 264
S+ + + ++W R QSRSFRILA +TGTEFMQDPDEE L++S
Sbjct: 110 SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQDPDEEHLKKS------------- 156
Query: 265 SSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGANYSPTPYTPSPA 324
S P T P PAS+ TP P P
Sbjct: 157 SQVPRTEA---------------------------PAPASS-----------TPQEPWPG 178
Query: 325 PAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDD 384
P PSP T P A P+ A Y P + ++PA+ P +
Sbjct: 179 PT-APSP------------TSRPPWAVDPAFAERYAPDKTSTVLTRHSQPATPTPLQSRT 225
Query: 385 SFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFPASSRTPLCGHC 444
S Q A G +P GG + +TP+C C
Sbjct: 226 SIVQAAAGG----------VPGGG------------------------SNNGKTPVCHQC 251
Query: 445 NNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCN 504
+ VIRG +LVA+G ++HPEEF C+ C L + F EE+ ++C CY+ +AP CAKC
Sbjct: 252 HKVIRGRYLVALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCK 311
Query: 505 TKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDF 564
KI GE+MHAL+ TWH CF CAACK P N F+ME+G PYCE+DY +F TKCHGCDF
Sbjct: 312 KKITGEIMHALKMTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDF 371
Query: 565 PVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612
++AGD+F+EALG +WHDTCF+CA+C +NLEG+ FYSKKDRPLCK HA
Sbjct: 372 KIDAGDRFLEALGFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 419
Score = 114 bits (284), Expect = 3e-25
Identities = 54/98 (55%), Positives = 73/98 (74%), Gaps = 3/98 (3%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTP 99
H+EAQNKI++ LSL L +++ P+ + VQTP
Sbjct: 63 HIEAQNKIRACGERLSLGLSRAQ---PVQSKPQKVQTP 97
>gi|11496885 PDZ and LIM domain 7 isoform 1 [Homo sapiens]
Length = 457
Score = 291 bits (744), Expect = 2e-78
Identities = 135/276 (48%), Positives = 180/276 (65%), Gaps = 14/276 (5%)
Query: 338 SPVPTYTPSPAPAYTPSPAPNYNP-APSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 396
S VP T +PAPA + P P APS P SRPPW D +F++++AP K++
Sbjct: 191 SQVPR-TEAPAPASSTPQEPWPGPTAPS---------PTSRPPWAVDPAFAERYAPDKTS 240
Query: 397 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAM 456
T +++ + P P + + A G V + +TP+C C+ VIRG +LVA+
Sbjct: 241 TVLTRHSQP-ATPTPLQSRTSIVQAAAGGVPGGGS--NNGKTPVCHQCHKVIRGRYLVAL 297
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G ++HPEEF C+ C L + F EE+ ++C CY+ +AP CAKC KI GE+MHAL+
Sbjct: 298 GHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCPPCYDVRYAPSCAKCKKKITGEIMHALK 357
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEAL 576
TWH CF CAACK P N F+ME+G PYCE+DY +F TKCHGCDF ++AGD+F+EAL
Sbjct: 358 MTWHVHCFTCAACKTPIRNRAFYMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEAL 417
Query: 577 GHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612
G +WHDTCF+CA+C +NLEG+ FYSKKDRPLCK HA
Sbjct: 418 GFSWHDTCFVCAICQINLEGKTFYSKKDRPLCKSHA 453
Score = 215 bits (548), Expect = 8e-56
Identities = 170/551 (30%), Positives = 236/551 (42%), Gaps = 107/551 (19%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
Query: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
F PS S T +P A +
Sbjct: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
Query: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 242 DPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPV 301
DPDEE L++S + +PA A+S+ P P P P + S P P
Sbjct: 181 DPDEEHLKKSSQVPRTEAPAPASST-----------PQEPWPGPTAPSPTSRPPWAVDPA 229
Query: 302 PASTYSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTYTP--SPAPAYTPSPAPNY 359
A Y+P + + T T PA TP+P+ + T A P N
Sbjct: 230 FAERYAP----DKTSTVLTRHSQPA---------TPTPLQSRTSIVQAAAGGVPGGGSNN 276
Query: 360 NPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKSTTSISKQTLPRGGPAYTPAGPQVP 419
P V + R ++ + + P + S + L GG P
Sbjct: 277 GKTP-VCHQ---CHKVIRGRYLV--ALGHAYHPEEFVCSQCGKVLEEGGFFEEKGAIFCP 330
Query: 420 PLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCF 479
P V+ A P C C I G + A+ +WH FTCA CKT + + F
Sbjct: 331 PCY--DVRYA---------PSCAKCKKKITGEIMHALKMTWHVHCFTCAACKTPIRNRAF 379
Query: 480 VEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHALRQTWHTTCFVCAACKKPFGNSL 537
E+ YCER YE+ F C C+ KI + AL +WH TCFVCA C+
Sbjct: 380 YMEEGVPYCERDYEKMFGTKCHGCDFKIDAGDRFLEALGFSWHDTCFVCAICQINLEGKT 439
Query: 538 FHMEDGEPYCE 548
F+ + P C+
Sbjct: 440 FYSKKDRPLCK 450
>gi|109638745 transforming growth factor beta 1 induced transcript 1
isoform 1 [Homo sapiens]
Length = 461
Score = 172 bits (436), Expect = 8e-43
Identities = 120/390 (30%), Positives = 165/390 (42%), Gaps = 52/390 (13%)
Query: 272 TSYSEGPAAPAPKPRVVTTASIRPSVYQPVPASTYSPSPGAN------YSPTPYTPSPAP 325
T+ S P + APK R + PS Y P + S GA+ YS SP P
Sbjct: 13 TTTSHMPRSGAPKERPAEPLTPPPS-YGHQPQTGSGESSGASGDKDHLYSTVCKPRSPKP 71
Query: 326 AYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN---------PAPSVAYSGGPAEPAS 376
A +P + + + T A +N P+ VA SG E S
Sbjct: 72 AAPAAPPFSSSSGVLGTGLCELDRLLQELNATQFNITDEIMSQFPSSKVA-SGEQKEDQS 130
Query: 377 ----RPPWVTDDSFSQKFAPGKSTT--------SIS----KQTLPRGGPAYTPA------ 414
RP + S A S T S+S + LP GP P
Sbjct: 131 EDKKRPSLPSSPSPGLPKASATSATLELDRLMASLSDFRVQNHLPASGPTQPPVVSSTNE 190
Query: 415 -GPQVP-PLARGTVQR---------AERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPE 463
P P P +G++ + R + LCG CN I G + A+GR+WHPE
Sbjct: 191 GSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNKPIAGQVVTALGRAWHPE 250
Query: 464 EFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTC 523
F C C T+L F E+ +C CY + F+P C CN I +++ AL WH
Sbjct: 251 HFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQPIRHKMVTALGTHWHPEH 310
Query: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
F C +C +PFG+ FH +G PYC +D++ LF+ +C GC P+ D +I AL WH
Sbjct: 311 FCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPIL--DNYISALSALWHPD 368
Query: 584 CFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
CF+C C G F+ + RPLC+ H H
Sbjct: 369 CFVCRECFAPFSGGSFFEHEGRPLCENHFH 398
Score = 124 bits (312), Expect = 2e-28
Identities = 60/172 (34%), Positives = 76/172 (44%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P CG CN IR + A+G WHPE F C C D F E + YC R + Q FA
Sbjct: 284 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 343
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C C I+ + AL WH CFVC C PF F +G P CE + +
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C C PV + + ALG +H F C C L F + +P C+
Sbjct: 404 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 453
Score = 75.5 bits (184), Expect = 1e-13
Identities = 34/117 (29%), Positives = 50/117 (42%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P C C I ++ A+ WHP+ F C C + F E + CE +
Sbjct: 344 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 403
Query: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LCA C + G + AL + +H F C C +P F G+PYC+ ++ LF
Sbjct: 404 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460
Score = 50.4 bits (119), Expect = 5e-06
Identities = 21/60 (35%), Positives = 30/60 (50%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C + G + A+GR +HP+ FTC +C L F E YC+ C+ + F
Sbjct: 401 RGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 460
>gi|21361591 transforming growth factor beta 1 induced transcript 1
isoform 2 [Homo sapiens]
Length = 444
Score = 172 bits (435), Expect = 1e-42
Identities = 81/227 (35%), Positives = 112/227 (49%), Gaps = 19/227 (8%)
Query: 404 LPRGGPAYTPA-------GPQVP-PLARGTVQR---------AERFPASSRTPLCGHCNN 446
LP GP P P P P +G++ + R + LCG CN
Sbjct: 157 LPASGPTQPPVVSSTNEGSPSPPEPTGKGSLDTMLGLLQSDLSRRGVPTQAKGLCGSCNK 216
Query: 447 VIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTK 506
I G + A+GR+WHPE F C C T+L F E+ +C CY + F+P C CN
Sbjct: 217 PIAGQVVTALGRAWHPEHFVCGGCSTALGGSSFFEKDGAPFCPECYFERFSPRCGFCNQP 276
Query: 507 IMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPV 566
I +++ AL WH F C +C +PFG+ FH +G PYC +D++ LF+ +C GC P+
Sbjct: 277 IRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFAPRCQGCQGPI 336
Query: 567 EAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
D +I AL WH CF+C C G F+ + RPLC+ H H
Sbjct: 337 L--DNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFH 381
Score = 124 bits (312), Expect = 2e-28
Identities = 60/172 (34%), Positives = 76/172 (44%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P CG CN IR + A+G WHPE F C C D F E + YC R + Q FA
Sbjct: 267 SPRCGFCNQPIRHKMVTALGTHWHPEHFCCVSCGEPFGDEGFHEREGRPYCRRDFLQLFA 326
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C C I+ + AL WH CFVC C PF F +G P CE + +
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C C PV + + ALG +H F C C L F + +P C+
Sbjct: 387 LCATCGLPVTG--RCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQ 436
Score = 75.5 bits (184), Expect = 1e-13
Identities = 34/117 (29%), Positives = 50/117 (42%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P C C I ++ A+ WHP+ F C C + F E + CE +
Sbjct: 327 PRCQGCQGPILDNYISALSALWHPDCFVCRECFAPFSGGSFFEHEGRPLCENHFHARRGS 386
Query: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LCA C + G + AL + +H F C C +P F G+PYC+ ++ LF
Sbjct: 387 LCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
Score = 50.4 bits (119), Expect = 5e-06
Identities = 21/60 (35%), Positives = 30/60 (50%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C + G + A+GR +HP+ FTC +C L F E YC+ C+ + F
Sbjct: 384 RGSLCATCGLPVTGRCVSALGRRFHPDHFTCTFCLRPLTKGSFQERAGKPYCQPCFLKLF 443
>gi|170932518 paxillin isoform 3 [Homo sapiens]
Length = 424
Score = 161 bits (408), Expect = 1e-39
Identities = 87/278 (31%), Positives = 125/278 (44%), Gaps = 13/278 (4%)
Query: 337 PSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 396
PSPVP T + +P + ++ S E ++D F + G S+
Sbjct: 96 PSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS 155
Query: 397 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVA 455
P GGP G Q+ + + A+ +CG C I G + A
Sbjct: 156 --------PPGGPP--KPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTA 205
Query: 456 MGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHAL 515
MG++WHPE F C +C+ + F E YCE+ Y F+P C CN I+ +V+ AL
Sbjct: 206 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 265
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+TWH F CA C FG FH +DG+ YC KDY ++F+ KC GC + + +I A
Sbjct: 266 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISA 323
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
L WH CF+C C F+ +P C+ H H
Sbjct: 324 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 361
Score = 131 bits (330), Expect = 2e-30
Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P C +CN I + A+ R+WHPE F CA C F E+ YC + Y FA
Sbjct: 247 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 306
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C C I+ + AL WH CFVC C PF N F DG+PYCE Y +
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C GC P+ + I A+ +H F+CA C L F + D+P C+
Sbjct: 367 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 416
Score = 85.1 bits (209), Expect = 2e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P CG C I ++ A+ WHPE F C C T + F E YCE Y +
Sbjct: 307 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 366
Query: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LC+ C I G + A+ + +H FVCA C K F ++ +PYC+ ++ LF
Sbjct: 367 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 53.9 bits (128), Expect = 4e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C I G + AM + +HPE F CA+C L F E+ + YC+ C+ + F
Sbjct: 364 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 423
Score = 42.7 bits (99), Expect = 0.001
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
C C P+ + + A+G TWH F+C C + + F+ + +P C+K H +
Sbjct: 191 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 245
>gi|170932516 paxillin isoform 2 [Homo sapiens]
Length = 557
Score = 161 bits (408), Expect = 1e-39
Identities = 87/278 (31%), Positives = 125/278 (44%), Gaps = 13/278 (4%)
Query: 337 PSPVPTYTPSPAPAYTPSPAPNYNPAPSVAYSGGPAEPASRPPWVTDDSFSQKFAPGKST 396
PSPVP T + +P + ++ S E ++D F + G S+
Sbjct: 229 PSPVPAITVNQGEMSSPQRVTSTQQQTRISASSATRELDELMASLSDFKFMAQGKTGSSS 288
Query: 397 TSISKQTLPRGGPAYTPAGPQVPPLARGTVQRAERFP-ASSRTPLCGHCNNVIRGPFLVA 455
P GGP G Q+ + + A+ +CG C I G + A
Sbjct: 289 --------PPGGPP--KPGSQLDSMLGSLQSDLNKLGVATVAKGVCGACKKPIAGQVVTA 338
Query: 456 MGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHAL 515
MG++WHPE F C +C+ + F E YCE+ Y F+P C CN I+ +V+ AL
Sbjct: 339 MGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPRCYYCNGPILDKVVTAL 398
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+TWH F CA C FG FH +DG+ YC KDY ++F+ KC GC + + +I A
Sbjct: 399 DRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKCGGCARAIL--ENYISA 456
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
L WH CF+C C F+ +P C+ H H
Sbjct: 457 LNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 494
Score = 131 bits (330), Expect = 2e-30
Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P C +CN I + A+ R+WHPE F CA C F E+ YC + Y FA
Sbjct: 380 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 439
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C C I+ + AL WH CFVC C PF N F DG+PYCE Y +
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C GC P+ + I A+ +H F+CA C L F + D+P C+
Sbjct: 500 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 549
Score = 85.1 bits (209), Expect = 2e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P CG C I ++ A+ WHPE F C C T + F E YCE Y +
Sbjct: 440 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 499
Query: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LC+ C I G + A+ + +H FVCA C K F ++ +PYC+ ++ LF
Sbjct: 500 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 53.9 bits (128), Expect = 4e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C I G + AM + +HPE F CA+C L F E+ + YC+ C+ + F
Sbjct: 497 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 556
Score = 42.7 bits (99), Expect = 0.001
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
C C P+ + + A+G TWH F+C C + + F+ + +P C+K H +
Sbjct: 324 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 378
>gi|221316659 leupaxin isoform 1 [Homo sapiens]
Length = 391
Score = 159 bits (401), Expect = 9e-39
Identities = 67/173 (38%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I G + A+G+SWHPE F C +CK + F E YC Y Q F+P C
Sbjct: 157 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 216
Query: 501 AKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 560
A C I+ +V+ A+ QTWH F C+ C + FG FH +D +PYC KD++ +FS KC
Sbjct: 217 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 276
Query: 561 GCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
GC+ PV + ++ A+ WH CF+C C + F+ RP C+ H H
Sbjct: 277 GCNRPVL--ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYH 327
Score = 125 bits (314), Expect = 1e-28
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P C +C I L AM ++WHPE F C++C F E+ YC + + F+
Sbjct: 213 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 272
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C CN ++ + A+ WH CFVC C F F DG P+CE Y + T
Sbjct: 273 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 332
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
CHGC P+ + I A+G+ +H F+CA C L F + D+ C+
Sbjct: 333 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 382
Score = 79.3 bits (194), Expect = 9e-15
Identities = 39/118 (33%), Positives = 53/118 (44%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P CG CN + +L AM WHPE F C C TS + F E +CE Y
Sbjct: 272 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 331
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LC C I G + A+ +H FVCA C +F ++ + YC+ + LF
Sbjct: 332 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
Score = 57.4 bits (137), Expect = 4e-08
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C I G + AMG +HPE F CA+C T L+ F E+ + YC+ C+ + F
Sbjct: 330 RGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 389
Score = 40.8 bits (94), Expect = 0.004
Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
C C P+ K I ALG +WH F+C C + PF+ + C H +
Sbjct: 157 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 211
>gi|4758670 leupaxin isoform 2 [Homo sapiens]
Length = 386
Score = 159 bits (401), Expect = 9e-39
Identities = 67/173 (38%), Positives = 93/173 (53%), Gaps = 2/173 (1%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I G + A+G+SWHPE F C +CK + F E YC Y Q F+P C
Sbjct: 152 CASCQKPIAGKVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQLFSPRC 211
Query: 501 AKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 560
A C I+ +V+ A+ QTWH F C+ C + FG FH +D +PYC KD++ +FS KC
Sbjct: 212 AYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFSPKCG 271
Query: 561 GCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
GC+ PV + ++ A+ WH CF+C C + F+ RP C+ H H
Sbjct: 272 GCNRPVL--ENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYH 322
Score = 125 bits (314), Expect = 1e-28
Identities = 57/172 (33%), Positives = 82/172 (47%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P C +C I L AM ++WHPE F C++C F E+ YC + + F+
Sbjct: 208 SPRCAYCAAPILDKVLTAMNQTWHPEHFFCSHCGEVFGAEGFHEKDKKPYCRKDFLAMFS 267
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C CN ++ + A+ WH CFVC C F F DG P+CE Y + T
Sbjct: 268 PKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRGT 327
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
CHGC P+ + I A+G+ +H F+CA C L F + D+ C+
Sbjct: 328 LCHGCGQPITG--RCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQ 377
Score = 79.3 bits (194), Expect = 9e-15
Identities = 39/118 (33%), Positives = 53/118 (44%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P CG CN + +L AM WHPE F C C TS + F E +CE Y
Sbjct: 267 SPKCGGCNRPVLENYLSAMDTVWHPECFVCGDCFTSFSTGSFFELDGRPFCELHYHHRRG 326
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LC C I G + A+ +H FVCA C +F ++ + YC+ + LF
Sbjct: 327 TLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
Score = 57.4 bits (137), Expect = 4e-08
Identities = 24/60 (40%), Positives = 33/60 (55%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C I G + AMG +HPE F CA+C T L+ F E+ + YC+ C+ + F
Sbjct: 325 RGTLCHGCGQPITGRCISAMGYKFHPEHFVCAFCLTQLSKGIFREQNDKTYCQPCFNKLF 384
Score = 40.8 bits (94), Expect = 0.004
Identities = 17/57 (29%), Positives = 24/57 (42%), Gaps = 2/57 (3%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
C C P+ K I ALG +WH F+C C + PF+ + C H +
Sbjct: 152 CASCQKPIAG--KVIHALGQSWHPEHFVCTHCKEEIGSSPFFERSGLAYCPNDYHQL 206
>gi|170932514 paxillin isoform 1 [Homo sapiens]
Length = 591
Score = 155 bits (391), Expect = 1e-37
Identities = 67/174 (38%), Positives = 92/174 (52%), Gaps = 2/174 (1%)
Query: 440 LCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPL 499
+CG C I G + AMG++WHPE F C +C+ + F E YCE+ Y F+P
Sbjct: 357 VCGACKKPIAGQVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNLFSPR 416
Query: 500 CAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKC 559
C CN I+ +V+ AL +TWH F CA C FG FH +DG+ YC KDY ++F+ KC
Sbjct: 417 CYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFAPKC 476
Query: 560 HGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAH 613
GC + + +I AL WH CF+C C F+ +P C+ H H
Sbjct: 477 GGCARAIL--ENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYH 528
Score = 131 bits (330), Expect = 2e-30
Identities = 62/172 (36%), Positives = 81/172 (47%), Gaps = 2/172 (1%)
Query: 438 TPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFA 497
+P C +CN I + A+ R+WHPE F CA C F E+ YC + Y FA
Sbjct: 414 SPRCYYCNGPILDKVVTALDRTWHPEHFFCAQCGAFFGPEGFHEKDGKAYCRKDYFDMFA 473
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFST 557
P C C I+ + AL WH CFVC C PF N F DG+PYCE Y +
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 558 KCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C GC P+ + I A+ +H F+CA C L F + D+P C+
Sbjct: 534 LCSGCQKPITG--RCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQ 583
Score = 85.1 bits (209), Expect = 2e-16
Identities = 39/117 (33%), Positives = 55/117 (47%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P CG C I ++ A+ WHPE F C C T + F E YCE Y +
Sbjct: 474 PKCGGCARAILENYISALNTLWHPECFVCRECFTPFVNGSFFEHDGQPYCEVHYHERRGS 533
Query: 499 LCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLF 555
LC+ C I G + A+ + +H FVCA C K F ++ +PYC+ ++ LF
Sbjct: 534 LCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 53.9 bits (128), Expect = 4e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Query: 437 RTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFF 496
R LC C I G + AM + +HPE F CA+C L F E+ + YC+ C+ + F
Sbjct: 531 RGSLCSGCQKPITGRCITAMAKKFHPEHFVCAFCLKQLNKGTFKEQNDKPYCQNCFLKLF 590
Score = 42.7 bits (99), Expect = 0.001
Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 2/57 (3%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHAHTI 615
C C P+ + + A+G TWH F+C C + + F+ + +P C+K H +
Sbjct: 358 CGACKKPIAG--QVVTAMGKTWHPEHFVCTHCQEEIGSRNFFERDGQPYCEKDYHNL 412
>gi|47157328 PDZ and LIM domain 7 isoform 4 [Homo sapiens]
Length = 222
Score = 140 bits (352), Expect = 5e-33
Identities = 92/251 (36%), Positives = 125/251 (49%), Gaps = 62/251 (24%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
S+ V L GP PWGFRLQGGKDFN+PL+ISR+TPG KAAQ+ ++ GD V++IDG N ++T
Sbjct: 3 SFKVVLEGPAPWGFRLQGGKDFNVPLSISRLTPGGKAAQAGVAVGDWVLSIDGENAGSLT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
H+EAQNKI++ LSL L + A PVQ+ + ++PA +
Sbjct: 63 HIEAQNKIRACGERLSLGLSR----------AQPVQS-------KPQKASAPAADPPRYT 105
Query: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
F PS S T +P A +
Sbjct: 106 FAPSV---SLNKTARP--------------------------------FGAPPPADSAPQ 130
Query: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQ 241
P++ L D+ S+ + + ++W R QSRSFRILA +TGTEFMQ
Sbjct: 131 QNGQPLRPLVPDA----------SKQRLMENTEDWRPRPGTGQSRSFRILAHLTGTEFMQ 180
Query: 242 DPDEEALRRSR 252
DPDEE L++SR
Sbjct: 181 DPDEEHLKKSR 191
>gi|58533159 PDZ and LIM domain 5 isoform d [Homo sapiens]
Length = 234
Score = 134 bits (337), Expect = 2e-31
Identities = 87/254 (34%), Positives = 128/254 (50%), Gaps = 55/254 (21%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQER 121
HLEAQNKIK + +L++TLQ++ +A P P+PV QK V S + QE
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPV---QKPTVTSVCSETSQEL 111
Query: 122 FNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDF 181
E + G + G ++ Q
Sbjct: 112 ----------------AEGQRRGSQ-------------------------GDSKQQNGKI 130
Query: 182 SGSLPIKDLAVDSASPVYQAVIKSQNKPE---DEADEWARRSSNLQSRSFRILAQMTGTE 238
P + V+ + Y S + ++ ++W R+ QSRSFRILAQ+TGTE
Sbjct: 131 PPKRPPRKHIVERYTEFYHVPTHSDASKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTE 190
Query: 239 FMQDPDEEALRRSR 252
+++ + + ++++
Sbjct: 191 HLKESEADNTKKAK 204
>gi|166235176 PDZ and LIM domain protein 3 isoform a [Homo sapiens]
Length = 364
Score = 131 bits (330), Expect = 2e-30
Identities = 94/275 (34%), Positives = 140/275 (50%), Gaps = 57/275 (20%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L GD+++AIDG T++M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSK--------------RPIPISTTAPPVQ--------- 97
TH +AQ++IK+A++ L L + + + P I+ + P
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHLWSPQVSEDGKAHPFKINLESEPQDGNYFEHKHN 120
Query: 98 -TPLP-VIPHQKVVVNSPANADY-QERFNPSALKD------------SALSTHKPIEVKG 142
P P VIP + ++P+ D R PS++ + L+ + P+E++
Sbjct: 121 IRPKPFVIPGRSSGCSTPSGIDCGSGRSTPSSVSTVSTICPGDLKVAAKLAPNIPLEMEL 180
Query: 143 LGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSDFSGSLPIKD---LAVDSASPVY 199
G K I+HAQ+NTP+ +YS D IM+ + GQ S G P+ +V S VY
Sbjct: 181 PGVK--IVHAQFNTPMQLYSDDNIMETLQGQV----STALGETPLMSEPTASVPPESDVY 234
Query: 200 QAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234
+ + ++N+P + QS SFR+L M
Sbjct: 235 RMLHDNRNEP----------TQPRQSGSFRVLQGM 259
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/51 (41%), Positives = 27/51 (52%)
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548
PLC KC + I+G V+ A + H CFVCA C + +GE YCE
Sbjct: 292 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
Score = 40.0 bits (92), Expect = 0.006
Identities = 19/55 (34%), Positives = 27/55 (49%)
Query: 435 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489
+ R PLC C + I G + A + HPE F CA C +L + + +YCE
Sbjct: 288 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 342
Score = 32.0 bits (71), Expect = 1.7
Identities = 11/32 (34%), Positives = 20/32 (62%)
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612
H CF+CA C++NL+ + ++ + C+ HA
Sbjct: 314 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 345
>gi|13994151 PDZ and LIM domain 1 [Homo sapiens]
Length = 329
Score = 129 bits (323), Expect = 1e-29
Identities = 96/292 (32%), Positives = 134/292 (45%), Gaps = 52/292 (17%)
Query: 5 VTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMTHLE 64
+ L GPGPWGFRL GGKDF PL ISR+TPGSKAA + L GD++ AIDG NT MTHLE
Sbjct: 6 IDLQGPGPWGFRLVGGKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLE 65
Query: 65 AQNKIKSASYNLSLTLQKSKRPI--PIST---TAPPVQTPLPVIPHQKVVVNSPANADYQ 119
AQN+IK + NL+LT+ +S+ + P+ T P + L P + + + S N
Sbjct: 66 AQNRIKGCTDNLTLTVARSEHKVWSPLVTEEGKRHPYKMNLASEPQEVLHIGSAHNRSAM 125
Query: 120 ERFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMD--------AIA 171
P ++ +T A +I QYN P +YS + I + A
Sbjct: 126 ----PFTASPASSTT------------ARVITNQYNNPAGLYSSENISNFNNALESKTAA 169
Query: 172 GQAQAQGSDFSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRIL 231
+A + P L +D S VY+ + + Q E QS SF +L
Sbjct: 170 SGVEANSRPLDHAQPPSSLVIDKESEVYKMLQEKQELNEPPK----------QSTSFLVL 219
Query: 232 AQMTGTEFMQDPDEEALRRSRPQASSYSPAVAASSAPATHTSYSEGPAAPAP 283
++ +E DP++ + RS AP T + S G A P
Sbjct: 220 QEILESEEKGDPNKPSGFRS-------------VKAPVTKVAASIGNAQKLP 258
Score = 48.9 bits (115), Expect = 1e-05
Identities = 47/188 (25%), Positives = 73/188 (38%), Gaps = 23/188 (12%)
Query: 324 APAYTPSPAPAYTPSPVPTYTPSPAPAYTPSPAPNYN-------PAPSVAYSGGPAEPAS 376
A +T SPA + T + +PA Y+ N+N A V + P + A
Sbjct: 124 AMPFTASPASSTTARVITNQYNNPAGLYSSENISNFNNALESKTAASGVEANSRPLDHAQ 183
Query: 377 RPPWVTDDSFSQKFA-----------PGKSTTSISKQTLPRGGPAYTPAGPQVPPLARGT 425
P + D S+ + P +ST+ + Q + P P +
Sbjct: 184 PPSSLVIDKESEVYKMLQEKQELNEPPKQSTSFLVLQEILESEEKGDPNKPSGFRSVKAP 243
Query: 426 VQR-AERFPASSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADV--CFVEE 482
V + A + + P+C C I G F+ R HPE + C C T+L FVE+
Sbjct: 244 VTKVAASIGNAQKLPMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVED 303
Query: 483 QNNVYCER 490
Q +YCE+
Sbjct: 304 Q--IYCEK 309
Score = 35.8 bits (81), Expect = 0.12
Identities = 16/52 (30%), Positives = 23/52 (44%)
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEK 549
P+C KC T I+G + + H C+VC C + + YCEK
Sbjct: 258 PMCDKCGTGIVGVFVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEK 309
Score = 32.3 bits (72), Expect = 1.3
Identities = 12/41 (29%), Positives = 22/41 (53%)
Query: 572 FIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612
F++ H C++C C NL+ + + +D+ C+KHA
Sbjct: 271 FVKLRDRHRHPECYVCTDCGTNLKQKGHFFVEDQIYCEKHA 311
>gi|166235178 PDZ and LIM domain protein 3 isoform b [Homo sapiens]
Length = 316
Score = 122 bits (307), Expect = 7e-28
Identities = 79/234 (33%), Positives = 120/234 (51%), Gaps = 23/234 (9%)
Query: 1 MSYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTM 60
M +V L GP PWGFRL GG DFN PL I+RITPGSKAA + L GD+++AIDG T++M
Sbjct: 1 MPQTVILPGPAPWGFRLSGGIDFNQPLVITRITPGSKAAAANLCPGDVILAIDGFGTESM 60
Query: 61 THLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVNSPANADYQE 120
TH +AQ++IK+A++ L L + + + + +P V P + + + P +
Sbjct: 61 THADAQDRIKAAAHQLCLKIDRGETHL----WSPQVSEDGKAHPFKINLESEP------Q 110
Query: 121 RFNPSALKDSALSTHKPIEVKGLGGKATIIHAQYNTPISMYSQDAIMDAIAGQAQAQGSD 180
F P + + + K ++ A YN+PI +YS I DA+ GQ +
Sbjct: 111 EFKPIGTAHNR-RAQPFVAAANIDDKRQVVSASYNSPIGLYSTSNIQDALHGQLRGLIPS 169
Query: 181 FSGSLPIKDLAVDSASPVYQAVIKSQNKPEDEADEWARRSSNLQSRSFRILAQM 234
+ P +V S VY+ + ++N+P + QS SFR+L M
Sbjct: 170 SPQNEP--TASVPPESDVYRMLHDNRNEP----------TQPRQSGSFRVLQGM 211
Score = 45.4 bits (106), Expect = 2e-04
Identities = 21/51 (41%), Positives = 27/51 (52%)
Query: 498 PLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548
PLC KC + I+G V+ A + H CFVCA C + +GE YCE
Sbjct: 244 PLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
Score = 40.0 bits (92), Expect = 0.006
Identities = 19/55 (34%), Positives = 27/55 (49%)
Query: 435 SSRTPLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCE 489
+ R PLC C + I G + A + HPE F CA C +L + + +YCE
Sbjct: 240 AQRMPLCDKCGSGIVGAVVKARDKYRHPECFVCADCNLNLKQKGYFFIEGELYCE 294
Score = 32.0 bits (71), Expect = 1.7
Identities = 11/32 (34%), Positives = 20/32 (62%)
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLCKKHA 612
H CF+CA C++NL+ + ++ + C+ HA
Sbjct: 266 HPECFVCADCNLNLKQKGYFFIEGELYCETHA 297
>gi|54112385 four and a half LIM domains 3 [Homo sapiens]
Length = 280
Score = 119 bits (298), Expect = 8e-27
Identities = 55/155 (35%), Positives = 75/155 (48%), Gaps = 2/155 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G++WH F C+ C+ L FV ++ YC CYE FAP CA+C+ + +
Sbjct: 119 GQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRD 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Q WH C VC C+ P F D +PYC + LF+ KC C P+ G K++
Sbjct: 179 QPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVS 238
Query: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
WH CF CA C +L GQ F D+ LC+
Sbjct: 239 FEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Score = 100 bits (250), Expect = 3e-21
Identities = 53/172 (30%), Positives = 76/172 (44%), Gaps = 6/172 (3%)
Query: 441 CGHCNNVIRGPF--LVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
C C +I L R +H F C C+ SLAD F + + + C CY F+
Sbjct: 40 CAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSS 99
Query: 499 LCAKCNTKIM--GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFS 556
C+ C +M + QTWH CF+C+ C++P G+ F + G YC Y N F+
Sbjct: 100 QCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFA 159
Query: 557 TKCHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
+C C + G + WH C +C C L GQ F S+ + P C
Sbjct: 160 PRCARCSKTLTQGG--VTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYC 209
Score = 94.7 bits (234), Expect = 2e-19
Identities = 46/148 (31%), Positives = 68/148 (45%), Gaps = 2/148 (1%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQT--WH 520
E F CA C SL +++ + YC CY+ FA CA+C I + + +H
Sbjct: 3 ESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
CF C C++ + F +D E C Y + FS++C C V G + +E G TW
Sbjct: 63 EGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H+ CF+C+ C L + F K C
Sbjct: 123 HEHCFLCSGCEQPLGSRSFVPDKGAHYC 150
Score = 65.5 bits (158), Expect = 1e-10
Identities = 31/114 (27%), Positives = 47/114 (41%), Gaps = 4/114 (3%)
Query: 439 PLCGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAP 498
P C C+ + + + WH E C C+T LA F + YC C+ + FAP
Sbjct: 160 PRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAP 219
Query: 499 LCAKCNTKIM----GEVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCE 548
C+ C I+ G+ + + WH CF CA C F + + C+
Sbjct: 220 KCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQ 273
Score = 40.0 bits (92), Expect = 0.006
Identities = 35/125 (28%), Positives = 46/125 (36%), Gaps = 22/125 (17%)
Query: 386 FSQKFAPGKSTTSISKQTLPRGGPAYTP----------AGPQVPPLARGTVQRAE----- 430
+ KFAP + S +TL +GG Y G Q P + R E
Sbjct: 154 YENKFAPRCARCS---KTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCV 210
Query: 431 RFPASSRTPLCGHCNNVI----RGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNV 486
P C C I G ++ R WH F+CA C TSL FV + + V
Sbjct: 211 ACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQV 270
Query: 487 YCERC 491
C+ C
Sbjct: 271 LCQGC 275
>gi|58533161 PDZ and LIM domain 5 isoform e [Homo sapiens]
Length = 214
Score = 117 bits (293), Expect = 3e-26
Identities = 59/110 (53%), Positives = 77/110 (70%), Gaps = 8/110 (7%)
Query: 2 SYSVTLTGPGPWGFRLQGGKDFNMPLTISRITPGSKAAQSQLSQGDLVVAIDGVNTDTMT 61
+YSV+L GP PWGFRLQGGKDFNMPLTIS + G KAAQ+ + GD+V++IDG+N MT
Sbjct: 3 NYSVSLVGPAPWGFRLQGGKDFNMPLTISSLKDGGKAAQANVRIGDVVLSIDGINAQGMT 62
Query: 62 HLEAQNKIKSASYNLSLTLQKSKRPIPISTTAPPVQTPLPVIPHQKVVVN 111
HLEAQNKIK + +L++TLQ++ +A P P+PV +V N
Sbjct: 63 HLEAQNKIKGCTGSLNMTLQRA--------SAAPKPEPVPVQKKTQVTNN 104
Score = 43.1 bits (100), Expect = 7e-04
Identities = 17/48 (35%), Positives = 34/48 (70%)
Query: 205 SQNKPEDEADEWARRSSNLQSRSFRILAQMTGTEFMQDPDEEALRRSR 252
S+ + ++ ++W R+ QSRSFRILAQ+TGTE +++ + + ++++
Sbjct: 137 SKKRLIEDTEDWRPRTGTTQSRSFRILAQITGTEHLKESEADNTKKAK 184
>gi|66932982 filamin-binding LIM protein-1 isoform a [Homo sapiens]
Length = 373
Score = 113 bits (283), Expect = 5e-25
Identities = 88/305 (28%), Positives = 127/305 (41%), Gaps = 31/305 (10%)
Query: 322 SPAPAYTPSPAPAYTPSPVPTYTPSPAPAYTP-SPAPNYN---PAPSVAYSGGPA----- 372
+PAP TP A PSP T P A A P +P +N P P G
Sbjct: 45 APAPMKTPEAGLAGRPSPWTT--PGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLD 102
Query: 373 --EPASRPPWVTDDSFSQKFAPGKSTTSISKQTL---PRGGPAYTPA-GPQVPPLARGTV 426
P PP V S + AP ++ + L P P PA GP V P +
Sbjct: 103 LLPPPPPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPM 162
Query: 427 QR------AERFPASSRTPLCGHCNNVI--RGPFLVAMGRSWHPEEFTCAYCKTSLADVC 478
+ AE + T +C C+ + R + AM R +H + FTC C+ LA
Sbjct: 163 EEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQS 222
Query: 479 FVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALRQTWHTTCFVCAACKKPFGNSLF 538
F ++ CE CY+ C KC + ++ AL Q +H +CF C C + G+ F
Sbjct: 223 FYQKDGRPLCEPCYQDTL-ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESF 281
Query: 539 HM-EDGEPYCEKDYINLFSTKCHGCDFPV---EAGDKF-IEALGHTWHDTCFICAVCHVN 593
+ E YC D+ F+ C C+ P+ + D F IE +G +H+ C+ C C +
Sbjct: 282 ALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRIL 341
Query: 594 LEGQP 598
L +P
Sbjct: 342 LSVEP 346
Score = 76.3 bits (186), Expect = 8e-14
Identities = 83/349 (23%), Positives = 122/349 (34%), Gaps = 59/349 (16%)
Query: 249 RRSRP---QASSYSPAVAASSAPATHTSYSEGPAAPAPKPRVVTTASIRPSVYQPVPAST 305
RR RP A +P + P+ T+ A P + P P
Sbjct: 38 RRGRPWEAPAPMKTPEAGLAGRPSPWTTPGRAAATVPAAPMQLFNGGCPPP---PPVLDG 94
Query: 306 YSPSPGANYSPTPYTPSPAPAYTPSPAPAYTPSPVPTY--------TPSPAPAYTPSPAP 357
P + P P P P P PS A P +P P P P+ P
Sbjct: 95 EDVLPDLDLLPPP--PPPPPVLLPSEEEAPAPMGASLIADLEQLHLSPPPPPPQAPAEGP 152
Query: 358 NYNPAP----SVAYSGGPAEPASRPPWVTDDSFSQK-FAPGKSTTSISKQ---------- 402
+ P P PAEP + +F K +P + K+
Sbjct: 153 SVQPGPLRPMEEELPPPPAEPVEKGASTDICAFCHKTVSPRELAVEAMKRQYHAQCFTCR 212
Query: 403 TLPR---GGPAYTPAG-PQVPPLARGTVQRAERFPASSRTPLCGHCNNVIRGPFLVAMGR 458
T R G Y G P P + T++R CG C V+R + A+G+
Sbjct: 213 TCRRQLAGQSFYQKDGRPLCEPCYQDTLER------------CGKCGEVVRDHIIRALGQ 260
Query: 459 SWHPEEFTCAYCKTSLADVCF-VEEQNNVYCERCYEQFFAPLCAKCNTKIMGE------V 511
++HP FTC C + D F + QN VYC + + FAP+C+ C I+
Sbjct: 261 AFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFAPVCSICENPIIPRDGKDAFK 320
Query: 512 MHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCH 560
+ + + +H C+ C C+ L +E + C +LF CH
Sbjct: 321 IECMGRNFHENCYRCEDCR-----ILLSVEPTDQGCYPLNNHLFCKPCH 364
Score = 46.2 bits (108), Expect = 9e-05
Identities = 20/51 (39%), Positives = 25/51 (49%)
Query: 559 CHGCDFPVEAGDKFIEALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLCK 609
C C V + +EA+ +H CF C C L GQ FY K RPLC+
Sbjct: 183 CAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCE 233
>gi|87159836 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (280), Expect = 1e-24
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Query: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH+ CF C C ++L G+ F +++D LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 103 bits (257), Expect = 5e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F ++ D C
Sbjct: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 92.0 bits (227), Expect = 1e-18
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612
H+TCFIC C + + F K ++ C K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
Query: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550
A C I G + + + WH CF C C F E + P C KD
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|87159834 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (280), Expect = 1e-24
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Query: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH+ CF C C ++L G+ F +++D LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 103 bits (257), Expect = 5e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F ++ D C
Sbjct: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 92.0 bits (227), Expect = 1e-18
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612
H+TCFIC C + + F K ++ C K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
Query: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550
A C I G + + + WH CF C C F E + P C KD
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|42403575 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (280), Expect = 1e-24
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Query: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH+ CF C C ++L G+ F +++D LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 103 bits (257), Expect = 5e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F ++ D C
Sbjct: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 92.0 bits (227), Expect = 1e-18
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612
H+TCFIC C + + F K ++ C K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
Query: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550
A C I G + + + WH CF C C F E + P C KD
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|87159832 four and a half LIM domains 2 [Homo sapiens]
Length = 279
Score = 112 bits (280), Expect = 1e-24
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 2/154 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G SWH F C C+ + F+ + N +C CYE+ A C +C I +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYRE 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVE--AGDKFIE 574
Q WH CFVC AC+K F D YC + +L++ KC GC P+ G K+I
Sbjct: 179 QPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYIS 238
Query: 575 ALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH+ CF C C ++L G+ F +++D LC
Sbjct: 239 FEERQWHNDCFNCKKCSLSLVGRGFLTERDDILC 272
Score = 103 bits (257), Expect = 5e-22
Identities = 47/153 (30%), Positives = 70/153 (45%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIM--GEVMHAL 515
R WH F C+ C+ SL D F +++ + C CY ++ C +C IM M
Sbjct: 59 RHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
+WH TCF+C C++P G F +D + +C Y + +C C P+ G +
Sbjct: 119 GSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGG--VTY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F ++ D C
Sbjct: 177 REQPWHKECFVCTACRKQLSGQRFTARDDFAYC 209
Score = 92.0 bits (227), Expect = 1e-18
Identities = 46/157 (29%), Positives = 74/157 (47%), Gaps = 7/157 (4%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E F C +C SL ++ + + YC C+E FA C +C I + + + WH
Sbjct: 3 ERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
CF C+ C+ + F ++ + C Y N +S+KC C + G + +E G +W
Sbjct: 63 EACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC-----KKHA 612
H+TCFIC C + + F K ++ C K+HA
Sbjct: 123 HETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHA 159
Score = 58.2 bits (139), Expect = 2e-08
Identities = 26/88 (29%), Positives = 41/88 (46%)
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
T F C C + + + + PYC + LF+ C C P+ K + W
Sbjct: 2 TERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHW 61
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H+ CF C+ C +L +PF +K+D+ LC
Sbjct: 62 HEACFHCSQCRNSLVDKPFAAKEDQLLC 89
Score = 55.1 bits (131), Expect = 2e-07
Identities = 32/117 (27%), Positives = 43/117 (36%), Gaps = 7/117 (5%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C C I + + WH E F C C+ L+ F + YC C+ +A C
Sbjct: 162 CVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKC 221
Query: 501 AKCNTKIMG----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGE---PYCEKD 550
A C I G + + + WH CF C C F E + P C KD
Sbjct: 222 AGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKD 278
>gi|228480213 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 112 bits (279), Expect = 1e-24
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA---GDKFI 573
Q WH CFVC C K F + + YC Y N + KC GC P+ G +
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 574 EALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
G +WHD CF C C VNL + F +++ C
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 99.0 bits (245), Expect = 1e-20
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H CF C+ C + F+ K + C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 89.4 bits (220), Expect = 9e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F + +D+ C
Sbjct: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 70.5 bits (171), Expect = 4e-12
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
Query: 501 AKCNTKIMG-----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
A C I G V+ Q+WH CF C C N F + YC
Sbjct: 222 AGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610
CF CA C L + F +K ++ LC K
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNK 91
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 441 CGHCNNVI----RGPFLVAM-GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 491
C C N I +G +VA G+SWH F C C +LA+ FV Q VYC C
Sbjct: 221 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276
>gi|228480207 four and a half LIM domains 1 isoform 2 [Homo sapiens]
Length = 280
Score = 112 bits (279), Expect = 1e-24
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 178
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA---GDKFI 573
Q WH CFVC C K F + + YC Y N + KC GC P+ G +
Sbjct: 179 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 238
Query: 574 EALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
G +WHD CF C C VNL + F +++ C
Sbjct: 239 AYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 99.0 bits (245), Expect = 1e-20
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 3 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 62
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 63 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 122
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H CF C+ C + F+ K + C
Sbjct: 123 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 150
Score = 89.4 bits (220), Expect = 9e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 59 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 118
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 119 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 176
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F + +D+ C
Sbjct: 177 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 209
Score = 70.5 bits (171), Expect = 4e-12
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 162 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 221
Query: 501 AKCNTKIMG-----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
A C I G V+ Q+WH CF C C N F + YC
Sbjct: 222 AGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 273
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 5 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 64
Query: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610
CF CA C L + F +K ++ LC K
Sbjct: 65 CFRCAKCLHPLANETFVAKDNKILCNK 91
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 441 CGHCNNVI----RGPFLVAM-GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 491
C C N I +G +VA G+SWH F C C +LA+ FV Q VYC C
Sbjct: 221 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 276
>gi|228480209 four and a half LIM domains 1 isoform 3 [Homo sapiens]
Length = 309
Score = 112 bits (279), Expect = 1e-24
Identities = 53/155 (34%), Positives = 70/155 (45%), Gaps = 3/155 (1%)
Query: 457 GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEVMHALR 516
G WH + FTC+ CK + F + + YC C+E FA C KCN I +
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGGITYQD 207
Query: 517 QTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEA---GDKFI 573
Q WH CFVC C K F + + YC Y N + KC GC P+ G +
Sbjct: 208 QPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKCAGCKNPITGFGKGSSVV 267
Query: 574 EALGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
G +WHD CF C C VNL + F +++ C
Sbjct: 268 AYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 99.0 bits (245), Expect = 1e-20
Identities = 48/148 (32%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Query: 463 EEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMGEV--MHALRQTWH 520
E+F C YC+ L +V++ + C +C+++F A C +C I + +H + WH
Sbjct: 32 EKFDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWH 91
Query: 521 TTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTW 580
TCF CA C P N F +D + C K S KC GC + AGD+ +E G W
Sbjct: 92 DTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYKGTVW 151
Query: 581 HDTCFICAVCHVNLEGQPFYSKKDRPLC 608
H CF C+ C + F+ K + C
Sbjct: 152 HKDCFTCSNCKQVIGTGSFFPKGEDFYC 179
Score = 89.4 bits (220), Expect = 9e-18
Identities = 46/153 (30%), Positives = 68/153 (44%), Gaps = 4/153 (2%)
Query: 458 RSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLCAKCNTKIMG--EVMHAL 515
R WH F CA C LA+ FV + N + C +C + +P C C I+ + +
Sbjct: 88 RFWHDTCFRCAKCLHPLANETFVAKDNKILCNKCTTREDSPKCKGCFKAIVAGDQNVEYK 147
Query: 516 RQTWHTTCFVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEA 575
WH CF C+ CK+ G F + + YC + F+ C C+ + +G I
Sbjct: 148 GTVWHKDCFTCSNCKQVIGTGSFFPKGEDFYCVTCHETKFAKHCVKCNKAITSGG--ITY 205
Query: 576 LGHTWHDTCFICAVCHVNLEGQPFYSKKDRPLC 608
WH CF+C C L GQ F + +D+ C
Sbjct: 206 QDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYC 238
Score = 70.5 bits (171), Expect = 4e-12
Identities = 35/112 (31%), Positives = 44/112 (39%), Gaps = 5/112 (4%)
Query: 441 CGHCNNVIRGPFLVAMGRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERCYEQFFAPLC 500
C CN I + + WH + F C C LA F ++ YC CY+ F A C
Sbjct: 191 CVKCNKAITSGGITYQDQPWHADCFVCVTCSKKLAGQRFTAVEDQYYCVDCYKNFVAKKC 250
Query: 501 AKCNTKIMG-----EVMHALRQTWHTTCFVCAACKKPFGNSLFHMEDGEPYC 547
A C I G V+ Q+WH CF C C N F + YC
Sbjct: 251 AGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYC 302
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/87 (32%), Positives = 39/87 (44%)
Query: 524 FVCAACKKPFGNSLFHMEDGEPYCEKDYINLFSTKCHGCDFPVEAGDKFIEALGHTWHDT 583
F C C+ P + +DG C K + + C C P+ A K + WHDT
Sbjct: 34 FDCHYCRDPLQGKKYVQKDGHHCCLKCFDKFCANTCVECRKPIGADSKEVHYKNRFWHDT 93
Query: 584 CFICAVCHVNLEGQPFYSKKDRPLCKK 610
CF CA C L + F +K ++ LC K
Sbjct: 94 CFRCAKCLHPLANETFVAKDNKILCNK 120
Score = 41.2 bits (95), Expect = 0.003
Identities = 23/56 (41%), Positives = 28/56 (50%), Gaps = 5/56 (8%)
Query: 441 CGHCNNVI----RGPFLVAM-GRSWHPEEFTCAYCKTSLADVCFVEEQNNVYCERC 491
C C N I +G +VA G+SWH F C C +LA+ FV Q VYC C
Sbjct: 250 CAGCKNPITGFGKGSSVVAYEGQSWHDYCFHCKKCSVNLANKRFVFHQEQVYCPDC 305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.130 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,513,231
Number of Sequences: 37866
Number of extensions: 1935082
Number of successful extensions: 39089
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 709
Number of HSP's successfully gapped in prelim test: 1452
Number of HSP's that attempted gapping in prelim test: 12949
Number of HSP's gapped (non-prelim): 10802
length of query: 617
length of database: 18,247,518
effective HSP length: 108
effective length of query: 509
effective length of database: 14,157,990
effective search space: 7206416910
effective search space used: 7206416910
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.