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Search of human proteins with 24475863
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24475863 H1 histone family, member O, oocyte-specific [Homo
sapiens]
(346 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24475863 H1 histone family, member O, oocyte-specific [Homo s... 677 0.0
gi|4885381 histone cluster 1, H1b [Homo sapiens] 71 2e-12
gi|4885379 histone cluster 1, H1e [Homo sapiens] 70 2e-12
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 70 4e-12
gi|4885375 histone cluster 1, H1c [Homo sapiens] 68 1e-11
gi|56676330 HP1-BP74 [Homo sapiens] 66 4e-11
gi|4885377 histone cluster 1, H1d [Homo sapiens] 66 5e-11
gi|5174449 H1 histone family, member X [Homo sapiens] 58 1e-08
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 57 2e-08
gi|4885371 H1 histone family, member 0 [Homo sapiens] 55 9e-08
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 55 9e-08
gi|4885373 histone cluster 1, H1a [Homo sapiens] 54 2e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 54 3e-07
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 53 5e-07
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo... 52 1e-06
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo... 52 1e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 52 1e-06
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens] 51 1e-06
gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithora... 51 2e-06
gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo ... 51 2e-06
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 50 3e-06
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 50 3e-06
gi|104526627 triadin [Homo sapiens] 50 3e-06
gi|237757312 synaptojanin 1 isoform c [Homo sapiens] 50 4e-06
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 50 4e-06
gi|30795231 brain abundant, membrane attached signal protein 1 [... 49 5e-06
gi|237757326 synaptojanin 1 isoform d [Homo sapiens] 49 5e-06
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 49 9e-06
gi|20544168 histone cluster 1, H1t [Homo sapiens] 49 9e-06
gi|145309324 FH2 domain containing 1 [Homo sapiens] 48 1e-05
>gi|24475863 H1 histone family, member O, oocyte-specific [Homo
sapiens]
Length = 346
Score = 677 bits (1748), Expect = 0.0
Identities = 346/346 (100%), Positives = 346/346 (100%)
Query: 1 MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVL 60
MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVL
Sbjct: 1 MAPGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVL 60
Query: 61 EALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARG 120
EALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARG
Sbjct: 61 EALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARG 120
Query: 121 ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRP 180
ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRP
Sbjct: 121 ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRP 180
Query: 181 AKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA 240
AKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA
Sbjct: 181 AKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA 240
Query: 241 KGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAA 300
KGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAA
Sbjct: 241 KGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAA 300
Query: 301 APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA 346
APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA
Sbjct: 301 APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA 346
>gi|4885381 histone cluster 1, H1b [Homo sapiens]
Length = 226
Score = 70.9 bits (172), Expect = 2e-12
Identities = 77/275 (28%), Positives = 119/275 (43%), Gaps = 51/275 (18%)
Query: 8 SDISPSSTST-AGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAG 66
S+ +P+ T+T A +SP +K G + PPV ++ +A+ A
Sbjct: 2 SETAPAETATPAPVEKSPAKKKATKKAAGAGAAKRKATG-------PPVSELITKAVAAS 54
Query: 67 EQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFK 126
++R G S+AA+K + DV + +K L + + +G L + +K GA+GSFK
Sbjct: 55 KERNGLSLAALKKALAAG--GYDVEKNNSRIKLGLKSLVSKGTLVQ---TKGTGASGSFK 109
Query: 127 LVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKP 186
L +K A A +A +A KKP+ A K KKAA V+K
Sbjct: 110 L---------NKKAASGEAKPKAKKAGAAKAKKPAGATPK-----KAKKAAGAKKAVKKT 155
Query: 187 PPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSS 246
P +KA+K A A+S + K KP KA ++P+ + KA
Sbjct: 156 P-------KKAKKPAAAGVKKVAKSPKKAKAAAKPKKATKSPAKPKAVKPKAA------- 201
Query: 247 QGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKK 281
+ A+ K++KP A+K K AA KKK
Sbjct: 202 -------KPKAAKPKAAKPKAAKAKKAAA---KKK 226
Score = 47.0 bits (110), Expect = 3e-05
Identities = 46/153 (30%), Positives = 66/153 (43%), Gaps = 29/153 (18%)
Query: 194 TEKARKQGGAAKDTRAQSGEARKVPPKPDKA--MRAPSSAGGLSRKAKAKGSRSSQGDAE 251
T+ G + +A SGEA+ PK KA +A AG +KAK + G +
Sbjct: 99 TKGTGASGSFKLNKKAASGEAK---PKAKKAGAAKAKKPAGATPKKAK-----KAAGAKK 150
Query: 252 AYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVV 311
A +KT ++K KP A+ VK A SP K K AK P K + S
Sbjct: 151 AVKKTPKKAK--KPAAAGVKKVAKSPKKAKAAAK----------------PKKATKSPAK 192
Query: 312 PAHLSRKTEAPKGPR-KAGLPIKASSSKVSSQR 343
P + K PK + KA P A + K ++++
Sbjct: 193 PKAVKPKAAKPKAAKPKAAKPKAAKAKKAAAKK 225
Score = 41.2 bits (95), Expect = 0.001
Identities = 52/180 (28%), Positives = 70/180 (38%), Gaps = 23/180 (12%)
Query: 180 PAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPD---KAMRAPSSAGGLSR 236
PA V+K P K A +K GA R +G PP + KA+ A GLS
Sbjct: 12 PAPVEKSPAKKKAT----KKAAGAGAAKRKATG-----PPVSELITKAVAASKERNGLSL 62
Query: 237 KAKAKGSRSSQGDAEAYR---KTKAESKSSKPTASKVKNGAASPT---KKKVVAKAKAPK 290
A K + D E K +S SK T + K AS + KK + PK
Sbjct: 63 AALKKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEAKPK 122
Query: 291 AGQGPNTKAAAPAKGSGSKVVPAHLSRKT-----EAPKGPRKAGLPIKASSSKVSSQRAE 345
A + KA PA + K A ++K + K P AG+ A S K + A+
Sbjct: 123 AKKAGAAKAKKPAGATPKKAKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK 182
Score = 33.9 bits (76), Expect = 0.22
Identities = 54/203 (26%), Positives = 77/203 (37%), Gaps = 13/203 (6%)
Query: 145 APRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAA 204
AP AK K KK + A G K+ A P + A+ E+ A
Sbjct: 13 APVEKSPAKKKATKKAAGA-------GAAKRKATGPPVSELITKAVAASKERNGLSLAAL 65
Query: 205 KDTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSS 263
K A G + K + +++ S G L + K G+ S + +A+ K+
Sbjct: 66 KKALAAGGYDVEKNNSRIKLGLKSLVSKGTLVQ-TKGTGASGSFKLNKKAASGEAKPKAK 124
Query: 264 KPTASKVKNGAASPTKKKVVAKAK-APKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEA- 321
K A+K K A + KK KA A KA + KA PA KV + K A
Sbjct: 125 KAGAAKAKKPAGATPKK--AKKAAGAKKAVKKTPKKAKKPAAAGVKKVAKSPKKAKAAAK 182
Query: 322 PKGPRKAGLPIKASSSKVSSQRA 344
PK K+ KA K + +A
Sbjct: 183 PKKATKSPAKPKAVKPKAAKPKA 205
>gi|4885379 histone cluster 1, H1e [Homo sapiens]
Length = 219
Score = 70.5 bits (171), Expect = 2e-12
Identities = 68/230 (29%), Positives = 104/230 (45%), Gaps = 49/230 (21%)
Query: 53 PPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLAR 112
PPV ++ +A+ A ++R G S+AA+K + DV + +K L + + +G L +
Sbjct: 38 PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ 95
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGK 172
+K GA+GSFKL KK + P ++AG AK K P ++ +
Sbjct: 96 ---TKGTGASGSFKL----NKKAASGEAKPKA--KKAGAAKAKKPAGAAKKPKKATGAAT 146
Query: 173 VKKAAKR-PAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSA 231
KK+AK+ P K +KP GA K+ K+ AA KP KA ++P+ A
Sbjct: 147 PKKSAKKTPKKAKKPAAAAGAKKAKSPKKAKAA---------------KPKKAPKSPAKA 191
Query: 232 GGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKK 281
+ KA A+ K++KP A+K K AA KKK
Sbjct: 192 KAVKPKA-------------------AKPKTAKPKAAKPKKAAA---KKK 219
Score = 45.8 bits (107), Expect = 6e-05
Identities = 62/230 (26%), Positives = 88/230 (38%), Gaps = 34/230 (14%)
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKED-PPNVG 171
P+ KAR + G+ K + A A + R+G + K + A D N
Sbjct: 19 PVKKKARKSAGAAKRKASGPPVSELITKAVAASKERSGVSLAALKKALAAAGYDVEKNNS 78
Query: 172 KVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAK-DTRAQSGEARKVPPKPDKA--MRAP 228
++K K K K G+ K + +A SGEA+ PK KA +A
Sbjct: 79 RIKLGLKSLVS------KGTLVQTKGTGASGSFKLNKKAASGEAK---PKAKKAGAAKAK 129
Query: 229 SSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKA 288
AG + KA G+ + + KS+K T K K AA+ KK AK+
Sbjct: 130 KPAGAAKKPKKATGAATPK-------------KSAKKTPKKAKKPAAAAGAKK----AKS 172
Query: 289 PKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSK 338
PK + K A + V P KT P KA P KA++ K
Sbjct: 173 PKKAKAAKPKKAPKSPAKAKAVKPKAAKPKTAKP----KAAKPKKAAAKK 218
Score = 43.9 bits (102), Expect = 2e-04
Identities = 61/213 (28%), Positives = 83/213 (38%), Gaps = 56/213 (26%)
Query: 176 AAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPD---KAMRAPSSAG 232
A PA +K P K +KARK GAAK R SG PP + KA+ A
Sbjct: 8 APAAPAPAEKTPVK-----KKARKSAGAAK--RKASG-----PPVSELITKAVAASKERS 55
Query: 233 GLSRKAKAKGSRSSQGDAE-------------AYRKTKAESKSSKPTAS-----KVKNGA 274
G+S A K ++ D E + T ++K + + S K +G
Sbjct: 56 GVSLAALKKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGE 115
Query: 275 ASPTKKKVVAK--------AKAPKAGQGPNT----------KAAAPAKGSGSKVV----P 312
A P KK A AK PK G T KA PA +G+K
Sbjct: 116 AKPKAKKAGAAKAKKPAGAAKKPKKATGAATPKKSAKKTPKKAKKPAAAAGAKKAKSPKK 175
Query: 313 AHLSRKTEAPKGPRKA-GLPIKASSSKVSSQRA 344
A ++ +APK P KA + KA+ K + +A
Sbjct: 176 AKAAKPKKAPKSPAKAKAVKPKAAKPKTAKPKA 208
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 69.7 bits (169), Expect = 4e-12
Identities = 61/218 (27%), Positives = 91/218 (41%), Gaps = 17/218 (7%)
Query: 130 KHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK 189
K +K + + A +P +A + K P+EAK VK+ AK PA+ + P +
Sbjct: 565 KSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKE 624
Query: 190 PGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGD 249
+ + + A T+ ++ P+KA KAK+ ++
Sbjct: 625 EAKSPAEVKSPEKAKSPTKEEA-------KSPEKAKSPEKEEAKSPEKAKSPVKAEAKSP 677
Query: 250 AEAYRKTKAESKSSKPTASKVKNGAASPTKKK--VVAKAKAPKAGQGPNTKAAAPAKGSG 307
+A KAE+KS + S VK A SP K K V +AK+P+ KA +P K
Sbjct: 678 EKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPE-------KAKSPVKEEA 730
Query: 308 SKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAE 345
A K EA K P KA P KA + V S A+
Sbjct: 731 KTPEKAKSPVKEEA-KSPEKAKSPEKAKTLDVKSPEAK 767
Score = 67.0 bits (162), Expect = 2e-11
Identities = 64/212 (30%), Positives = 93/212 (43%), Gaps = 23/212 (10%)
Query: 130 KHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK 189
K +K + + A +P +A K P K EAK P K+ AK PA+V+ P
Sbjct: 531 KSPEKEEAKSPAEVKSPEKA-----KSPAK-EEAKSPPEAKSPEKEEAKSPAEVKSPEKA 584
Query: 190 PGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGD 249
A E+A+ A+S E K P K + ++P+ A K +AK +
Sbjct: 585 KSPAKEEAKSPA------EAKSPEKAKSPVKEEA--KSPAEAKS-PVKEEAKSPAEVKSP 635
Query: 250 AEAYRKTKAESKSSKPTASKVKNGAASPTKKK--VVAKAKAPKAGQGP-NTKAAAPAKGS 306
+A TK E+KS + S K A SP K K V A+AK+P+ + P +A +P K
Sbjct: 636 EKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAK 695
Query: 307 GSKVVPAHLSRKTEAP-----KGPRKAGLPIK 333
A K ++P K P KA P+K
Sbjct: 696 SPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727
Score = 63.9 bits (154), Expect = 2e-10
Identities = 55/198 (27%), Positives = 82/198 (41%), Gaps = 17/198 (8%)
Query: 150 GEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK----------PGAATEKARK 199
GE + K P A + VK+ AK PA+ + P + P A A++
Sbjct: 497 GEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKE 556
Query: 200 QGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAE 259
+ + + ++ E K P + +A S A K +AK ++ +A K E
Sbjct: 557 EAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPA-----KEEAKSPAEAKSPEKAKSPVKEE 611
Query: 260 SKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPN-TKAAAPAKGSGSKVVPAHLSRK 318
+KS S VK A SP + K KAK+P + + KA +P K A K
Sbjct: 612 AKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVK 671
Query: 319 TEAPKGPRKAGLPIKASS 336
EA K P KA P+KA +
Sbjct: 672 AEA-KSPEKAKSPVKAEA 688
Score = 60.1 bits (144), Expect = 3e-09
Identities = 61/208 (29%), Positives = 87/208 (41%), Gaps = 26/208 (12%)
Query: 141 APATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKAR-- 198
+P + E + K P K EAK K+ AK PA+V+ P A E+A+
Sbjct: 503 SPPAEEAASPEKEAKSPVK-EEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP 561
Query: 199 ------KQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEA 252
++ A +S E K P K + ++P+ A KAK+ ++ AEA
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEA--KSPAEAKS-PEKAKSPVKEEAKSPAEA 618
Query: 253 YRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPN-------TKAAAPAKG 305
K E+KS P K A SPTK++ AK+P+ + P KA +P K
Sbjct: 619 KSPVKEEAKS--PAEVKSPEKAKSPTKEE----AKSPEKAKSPEKEEAKSPEKAKSPVKA 672
Query: 306 SGSKVVPAHLSRKTEAPKGPRKAGLPIK 333
A K EA K P KA P+K
Sbjct: 673 EAKSPEKAKSPVKAEA-KSPEKAKSPVK 699
Score = 56.2 bits (134), Expect = 4e-08
Identities = 60/229 (26%), Positives = 94/229 (41%), Gaps = 16/229 (6%)
Query: 130 KHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK 189
K + K + +P A ++ E K K P K +EAK VK+ AK P K + P +
Sbjct: 657 KEEAKSPEKAKSPVKAEAKSPE-KAKSPVK-AEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 190 PGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGL---SRKAKAKGSRSS 246
+ EKA+ T ++ K K + ++P A L S +AK +
Sbjct: 715 EAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEA 774
Query: 247 QGDAEAYRK-----TKAESKSSKPTASKVKNGAASPTK---KKVVAKAKAPKAGQGPNTK 298
+ A+ + + K E KS + S +K A +P K KK K+ + + K
Sbjct: 775 RSPADKFPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVK 834
Query: 299 AAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIK-ASSSKVSSQRAEA 346
P K + + PA + KTE K +K P K A KV ++ A
Sbjct: 835 VKEPPKKAEEEKAPA--TPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPA 881
Score = 51.2 bits (121), Expect = 1e-06
Identities = 63/239 (26%), Positives = 92/239 (38%), Gaps = 20/239 (8%)
Query: 121 ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRP 180
A K K +K + A A +P +A + K P +AK K + AK P
Sbjct: 666 AKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSP 725
Query: 181 AKVQ-------KPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGG 233
K + K P K A + + K AK +S EA K P K + A S A
Sbjct: 726 VKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEA-KTPAKEE----ARSPADK 780
Query: 234 LSRKAKAKGSRSSQGDAEAYRKTKAESKSSK---PTASKVKNGAASPTKKKVVAKAKAPK 290
KAK+ + +A K ++K+ + P +VK+ K + V + PK
Sbjct: 781 FPEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPK 840
Query: 291 AGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPK---GPRKAGLPIKASSSKVSSQRAEA 346
+ KA A K K + K EAPK +K K SKV +++ EA
Sbjct: 841 KAE--EEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEA 897
Score = 47.4 bits (111), Expect = 2e-05
Identities = 56/237 (23%), Positives = 91/237 (38%), Gaps = 17/237 (7%)
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGK 172
P +AR F K K + + A +P + K P+K KE+ + K
Sbjct: 769 PAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED---AKAPEKEIPKKEEVKSPVK 825
Query: 173 VKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAG 232
++ + KV++PP K A + KD++ + ++ P + + P+
Sbjct: 826 EEEKPQE-VKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEK 884
Query: 233 GLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAK----AKA 288
K +AK + +AE +K K + P +VK A K +V K AKA
Sbjct: 885 PKESKVEAK-----KEEAEDKKKVPTPEKEA-PAKVEVKEDAKPKEKTEVAKKEPDDAKA 938
Query: 289 PKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAE 345
+ + K AAP K + + E PK KA K S + S +AE
Sbjct: 939 KEPSKPAEKKEAAPEKKDTKE---EKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAE 992
Score = 46.2 bits (108), Expect = 4e-05
Identities = 48/187 (25%), Positives = 79/187 (42%), Gaps = 17/187 (9%)
Query: 162 EAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKP 221
E E+ +V + ++ AK ++ + G E+A G ++T++ E P K
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE---GGEEETKSPPAEEAASPEKE 515
Query: 222 DKA-----MRAPSSAGGLSRK-----AKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVK 271
K+ ++P+ A ++ A+ K ++ A+ K+ E+KS + +K
Sbjct: 516 AKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSP 575
Query: 272 NGAASPTKKKVVAK--AKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAG 329
SP K K AK AK+P + P KA +P K A K EA K P +
Sbjct: 576 AEVKSPEKAKSPAKEEAKSPAEAKSPE-KAKSPVKEEAKSPAEAKSPVKEEA-KSPAEVK 633
Query: 330 LPIKASS 336
P KA S
Sbjct: 634 SPEKAKS 640
Score = 44.7 bits (104), Expect = 1e-04
Identities = 41/185 (22%), Positives = 71/185 (38%), Gaps = 13/185 (7%)
Query: 173 VKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKD-TRAQSGEARKVPPKPDKAMRAPSSA 231
+K ++ KV + K E+ ++ ++ T + EA++ K ++ +
Sbjct: 436 IKVKSEEKIKVVEKSEKETVIVEEQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAE 495
Query: 232 GGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAP-- 289
GG ++ + EA K E+KS S K A SP + K KAK+P
Sbjct: 496 GGEEETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAK 555
Query: 290 ---------KAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEA-PKGPRKAGLPIKASSSKV 339
K+ + K+ A K PA K+ A K P KA P+K +
Sbjct: 556 EEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSP 615
Query: 340 SSQRA 344
+ ++
Sbjct: 616 AEAKS 620
Score = 42.0 bits (97), Expect = 8e-04
Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 14/154 (9%)
Query: 126 KLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEA------KEDPPNVGKVKKAAKR 179
K+ K + ++ K + A + E K K P EA KED K + A K
Sbjct: 873 KVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKE 932
Query: 180 PAKVQ-KPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRK- 237
P + K P KP E A ++ KDT+ + +A+K KP +A LS++
Sbjct: 933 PDDAKAKEPSKPAEKKEAAPEK----KDTKEE--KAKKPEEKPKTEAKAKEDDKTLSKEP 986
Query: 238 AKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVK 271
+K K ++ + + + +K K+++ A+K K
Sbjct: 987 SKPKAEKAEKSSSTDQKDSKPPEKATEDKAAKGK 1020
>gi|4885375 histone cluster 1, H1c [Homo sapiens]
Length = 213
Score = 68.2 bits (165), Expect = 1e-11
Identities = 64/217 (29%), Positives = 93/217 (42%), Gaps = 25/217 (11%)
Query: 13 SSTSTAGSSRSPESEK-PGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRG 71
S T+ A + +P +EK P GG P PPV ++ +A+ A ++R G
Sbjct: 2 SETAPAAPAAAPPAEKAPVKKKAAKKAGGT-----PRKASGPPVSELITKAVAASKERSG 56
Query: 72 TSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKH 131
S+AA+K + DV + +K L + + +G L + +K GA+GSFKL
Sbjct: 57 VSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ---TKGTGASGSFKL---- 107
Query: 132 KKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPG 191
+K A A + +A G PKKP A + P K K K KP
Sbjct: 108 -----NKKAASGEAKPKVKKAGGTKPKKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPA 162
Query: 192 AAT-----EKARKQGGAAKDTRAQSGEARKVPPKPDK 223
AAT K+ K+ AK +A A+ V PK K
Sbjct: 163 AATVTKKVAKSPKKAKVAKPKKAAKSAAKAVKPKAAK 199
Score = 40.4 bits (93), Expect = 0.002
Identities = 53/205 (25%), Positives = 77/205 (37%), Gaps = 19/205 (9%)
Query: 151 EAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKP------GAATEKARKQGGAA 204
E P A++ P KKA P K PP A+ E++ A
Sbjct: 3 ETAPAAPAAAPPAEKAPVKKKAAKKAGGTPRKASGPPVSELITKAVAASKERSGVSLAAL 62
Query: 205 KDTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSS 263
K A +G + K + +++ S G L + KG+ +S KA S +
Sbjct: 63 KKALAAAGYDVEKNNSRIKLGLKSLVSKGTL---VQTKGTGAS---GSFKLNKKAASGEA 116
Query: 264 KPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPK 323
KP K G P KK V AK PK G T + K PA + + K
Sbjct: 117 KPKVKKA--GGTKP--KKPVGAAKKPKKAAGGATPKKSAKKTPKKAKKPAAATVTKKVAK 172
Query: 324 GPRKAGL--PIKASSSKVSSQRAEA 346
P+KA + P KA+ S + + +A
Sbjct: 173 SPKKAKVAKPKKAAKSAAKAVKPKA 197
>gi|56676330 HP1-BP74 [Homo sapiens]
Length = 553
Score = 66.2 bits (160), Expect = 4e-11
Identities = 36/84 (42%), Positives = 56/84 (66%), Gaps = 3/84 (3%)
Query: 53 PPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLAR 112
P + ++ EA++A Q+ G SV AI+ YI+HKYP++++ R YLLKQAL + RG++ +
Sbjct: 159 PKMDAILTEAIKACFQKSGASVVAIRKYIIHKYPSLELERRGYLLKQALKRELNRGVIKQ 218
Query: 113 PLNSKARGATGSFKLVPKHKKKIQ 136
K +GA+GSF +V K +K Q
Sbjct: 219 ---VKGKGASGSFVVVQKSRKTPQ 239
Score = 56.2 bits (134), Expect = 4e-08
Identities = 59/216 (27%), Positives = 91/216 (42%), Gaps = 19/216 (8%)
Query: 59 VLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKA 118
+L A+ A + + S A+K Y+L +P + +LLK+ L + G + +
Sbjct: 346 ILSAIAAMNEPKTCSTTALKKYVLENHPGTNSNYQMHLLKKTLQKCEKNGWMEQ---ISG 402
Query: 119 RGATGSFKLVPKHKKKIQPRKMAPATAP---RRAGEAKGKGPKKPSEAKEDPPNVGKVKK 175
+G +G+F+L + P + P P R E + + ++ SE +E PP
Sbjct: 403 KGFSGTFQLCFPYYP--SPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPP------- 453
Query: 176 AAKRPAKVQKPPPKPG-AATEKARKQGGAAKDTRAQSGEARKVPPK-PDKAMRAPSSAGG 233
KR + + P PG AA+ K R A K + AQ G+AR +P K P KA
Sbjct: 454 --KRRLQKKTPAKSPGKAASVKQRGSKPAPKVSAAQRGKARPLPKKAPPKAKTPAKKTRP 511
Query: 234 LSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASK 269
S K SS+ A + RK K T K
Sbjct: 512 SSTVIKKPSGGSSKKPATSARKEVKLPGKGKSTMKK 547
Score = 39.7 bits (91), Expect = 0.004
Identities = 35/146 (23%), Positives = 53/146 (36%), Gaps = 24/146 (16%)
Query: 188 PKPGAATEK-----ARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKG 242
P PG K +R + ++ + E + PPK + P+ + G + K +G
Sbjct: 417 PSPGVLFPKKEPDDSRDEDEDEDESSEEDSEDEEPPPKRRLQKKTPAKSPGKAASVKQRG 476
Query: 243 SRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAP 302
S+ + P S + G A P KK KAK P P++
Sbjct: 477 SKPA------------------PKVSAAQRGKARPLPKKAPPKAKTPAKKTRPSSTVIKK 518
Query: 303 AKGSGSKVVPAHLSRKTEAPKGPRKA 328
G SK PA +RK G K+
Sbjct: 519 PSGGSSK-KPATSARKEVKLPGKGKS 543
>gi|4885377 histone cluster 1, H1d [Homo sapiens]
Length = 221
Score = 65.9 bits (159), Expect = 5e-11
Identities = 70/236 (29%), Positives = 104/236 (44%), Gaps = 55/236 (23%)
Query: 53 PPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLAR 112
PPV ++ +A+ A ++R G S+AA+K + DV + +K L + + +G L +
Sbjct: 39 PPVSELITKAVAASKERSGVSLAALKKALAAA--GYDVEKNNSRIKLGLKSLVSKGTLVQ 96
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGK 172
+K GA+GSFKL K +GE K K KK AK
Sbjct: 97 ---TKGTGASGSFKLNKK----------------AASGEGKPKA-KKAGAAK-------- 128
Query: 173 VKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAG 232
P KP A +K +K GAA ++ +K P K K P++A
Sbjct: 129 --------------PRKPAGAAKKPKKVAGAATPKKS----IKKTPKKVKK----PATAA 166
Query: 233 GLSRKAK-AKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAK 287
G + AK AK ++ Q A K+ A++K+ KP A+K K+G TK K A K
Sbjct: 167 GTKKVAKSAKKVKTPQPKKAA--KSPAKAKAPKPKAAKPKSGKPKVTKAKKAAPKK 220
Score = 35.8 bits (81), Expect = 0.058
Identities = 53/214 (24%), Positives = 89/214 (41%), Gaps = 41/214 (19%)
Query: 157 PKKPSEAKEDPPNVGKVKKAAKRPA------KVQKPPPKP------GAATEKARKQGGAA 204
P P+ A++ P VKK AK+ K PP A+ E++ A
Sbjct: 9 PTIPAPAEKTP-----VKKKAKKAGATAGKRKASGPPVSELITKAVAASKERSGVSLAAL 63
Query: 205 KDTRAQSG-EARKVPPKPDKAMRAPSSAGGL--SRKAKAKGS-----RSSQGDAEAYRKT 256
K A +G + K + +++ S G L ++ A GS +++ G+ + K
Sbjct: 64 KKALAAAGYDVEKNNSRIKLGLKSLVSKGTLVQTKGTGASGSFKLNKKAASGEGKPKAKK 123
Query: 257 KAESKSSKPTASKVKN----GAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVP 312
+K KP + K GAA+P K + K PK K PA +G+K V
Sbjct: 124 AGAAKPRKPAGAAKKPKKVAGAATPKK----SIKKTPK-------KVKKPATAAGTKKV- 171
Query: 313 AHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA 346
A ++K + P+ + A P KA + K + + ++
Sbjct: 172 AKSAKKVKTPQPKKAAKSPAKAKAPKPKAAKPKS 205
>gi|5174449 H1 histone family, member X [Homo sapiens]
Length = 213
Score = 57.8 bits (138), Expect = 1e-08
Identities = 55/169 (32%), Positives = 80/169 (47%), Gaps = 19/169 (11%)
Query: 57 RMVLEALQAGEQRRGTSVAAIKLYI-LHKYPTVDVLRFKYLLKQALATGMRRGLLARPLN 115
++V+E ++ +R G+S+A K+Y K P D + LK ++ ++ L L
Sbjct: 50 QLVVETIRRLGERNGSSLA--KIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDTL---LQ 104
Query: 116 SKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKK 175
K GA GSFKL K + R+ APA A A A +AK+ P ++
Sbjct: 105 VKGTGANGSFKLNRKKLEGGGERRGAPAAATAPAPTAH--------KAKKAAPGAAGSRR 156
Query: 176 AAKRPAKVQKPPP---KPGAATEKARKQGGAAKDTRAQSGEARKVPPKP 221
A K+PA+ QKP K GA +K +GG AK T A G+ K KP
Sbjct: 157 ADKKPARGQKPEQRSHKKGAGAKK--DKGGKAKKTAAAGGKKVKKAAKP 203
Score = 38.9 bits (89), Expect = 0.007
Identities = 59/215 (27%), Positives = 78/215 (36%), Gaps = 25/215 (11%)
Query: 97 LKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAP--RRAGEAKG 154
L++AL G+ + + A K KKK QP K + RR GE G
Sbjct: 5 LEEALPVTTAEGMAKKVTKAGGSAALSPSKKRKNSKKKNQPGKYSQLVVETIRRLGERNG 64
Query: 155 KGPKKP-SEAKEDP---PNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQ 210
K +EAK+ P G+ A VQ K G+ K R +
Sbjct: 65 SSLAKIYTEAKKVPWFDQQNGRTYLKYSIKALVQNDT----LLQVKGTGANGSFKLNRKK 120
Query: 211 ---SGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSK--P 265
GE R P A AP+ ++KA + S + D + R K E +S K
Sbjct: 121 LEGGGERRGAPA----AATAPAPTAHKAKKAAPGAAGSRRADKKPARGQKPEQRSHKKGA 176
Query: 266 TASKVKNGAASPT------KKKVVAKAKAPKAGQG 294
A K K G A T K K AK PK +G
Sbjct: 177 GAKKDKGGKAKKTAAAGGKKVKKAAKPSVPKVPKG 211
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 57.4 bits (137), Expect = 2e-08
Identities = 41/190 (21%), Positives = 65/190 (34%), Gaps = 20/190 (10%)
Query: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201
P P + G P P + + PP G + P K Q PPP+ G+ + +R
Sbjct: 242 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPP 301
Query: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESK 261
G + Q G + PP P + P GG K +
Sbjct: 302 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--------------------NKPQGPPP 341
Query: 262 SSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEA 321
KP + G+ S + + K + P +G N + P G + A + + +
Sbjct: 342 PGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQG 401
Query: 322 PKGPRKAGLP 331
P P + G P
Sbjct: 402 PPRPPQGGRP 411
Score = 53.1 bits (126), Expect = 4e-07
Identities = 47/205 (22%), Positives = 66/205 (32%), Gaps = 25/205 (12%)
Query: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201
P P + G P P + + PP G + P K Q PPP+ ++ AR
Sbjct: 180 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPP 239
Query: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESK 261
G + Q G + PP P + P GG K +
Sbjct: 240 GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG--------------------NKPQGPPP 279
Query: 262 SSKPTASKVKNGAASPTKKKVVAKAKA--PKAGQGPNTKAAAPAKGSGSKVVPAHLSRKT 319
KP + G+ S + + K + P+ G P P K G P K
Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP---PPQGGNKP 336
Query: 320 EAPKGPRKAGLPIKASSSKVSSQRA 344
+ P P K P SK S R+
Sbjct: 337 QGPPPPGKPQGPPPQGGSKSRSARS 361
Score = 51.2 bits (121), Expect = 1e-06
Identities = 50/222 (22%), Positives = 71/222 (31%), Gaps = 26/222 (11%)
Query: 146 PRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAK 205
P G K +GP P + + PP K + P K Q PPP+ G + G +
Sbjct: 81 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 140
Query: 206 DTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA----------KGSRSSQG------- 248
Q G + PP P K P SR +++ +G QG
Sbjct: 141 GPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK 200
Query: 249 ----DAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKA--PKAGQGPNTKAAAP 302
+ K + KP + S + + K + P+ G P P
Sbjct: 201 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPP 260
Query: 303 AKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344
K G P K + P P K P SK S R+
Sbjct: 261 GKPQGP---PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRS 299
Score = 45.8 bits (107), Expect = 6e-05
Identities = 53/216 (24%), Positives = 75/216 (34%), Gaps = 27/216 (12%)
Query: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201
P AP + G K +GP P + PP G +P Q PPP PG + QG
Sbjct: 36 PQGAPPQGGN-KPQGPPSPPGKPQGPPPQG-----GNQP---QGPPPPPGKP-QGPPPQG 85
Query: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQG-----------DA 250
G G+ + PP+ DK+ R+P S G + +G QG
Sbjct: 86 GNKPQGPPPPGKPQGPPPQGDKS-RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 144
Query: 251 EAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKA--PKAGQGPNTKAAAPAKGSGS 308
+ K + KP + S + + K + P+ G P P K G
Sbjct: 145 QGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 309 KVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344
P K + P P K P +K S R+
Sbjct: 205 ---PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARS 237
Score = 33.1 bits (74), Expect = 0.38
Identities = 28/110 (25%), Positives = 38/110 (34%), Gaps = 20/110 (18%)
Query: 131 HKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKP 190
+K + P P P + G P + + PP G + Q PPP P
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN---------QPQGPPPPP 322
Query: 191 GAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKA 240
G + QG Q G + PP P K P G SR A++
Sbjct: 323 G------KPQG-----PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARS 361
>gi|4885371 H1 histone family, member 0 [Homo sapiens]
Length = 194
Score = 55.1 bits (131), Expect = 9e-08
Identities = 44/177 (24%), Positives = 80/177 (45%), Gaps = 20/177 (11%)
Query: 52 HPPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVL--RFKYLLKQALATGMRRGL 109
HP M++ A+QA + R G+S +I+ YI Y + + K +K+ + TG+ +
Sbjct: 25 HPKYSDMIVAAIQAEKNRAGSSRQSIQKYIKSHYKVGENADSQIKLSIKRLVTTGVLK-- 82
Query: 110 LARPLNSKARGATGSFKLVPKHKKKIQ------PRKMAPATAPRRAGEAKGKGPKKPSEA 163
+K GA+GSF+L + K +++ P++A + K K P++
Sbjct: 83 -----QTKGVGASGSFRLAKSDEPKKSVAFKKTKKEIKKVATPKKASKPKKAASKAPTKK 137
Query: 164 KEDPPNVGKVKKAAKRPAKVQKP-----PPKPGAATEKARKQGGAAKDTRAQSGEAR 215
+ P KK A P K +KP P + +KA+ AK + ++G+ +
Sbjct: 138 PKATPVKKAKKKLAATPKKAKKPKTVKAKPVKASKPKKAKPVKPKAKSSAKRAGKKK 194
Score = 41.6 bits (96), Expect = 0.001
Identities = 56/205 (27%), Positives = 82/205 (40%), Gaps = 37/205 (18%)
Query: 141 APATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARK- 199
APA P+RA K S+ D P + AA +Q + G++ + +K
Sbjct: 8 APAAKPKRA---------KASKKSTDHPKYSDMIVAA-----IQAEKNRAGSSRQSIQKY 53
Query: 200 -----QGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYR 254
+ G D++ + R V K + ++G R AK+ + S A++
Sbjct: 54 IKSHYKVGENADSQIKLSIKRLVTTGVLKQTKGVGASGSF-RLAKSDEPKKSV----AFK 108
Query: 255 KTKAE-------SKSSKP--TASKV--KNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPA 303
KTK E K+SKP ASK K A+P KK A PK + P T A P
Sbjct: 109 KTKKEIKKVATPKKASKPKKAASKAPTKKPKATPVKKAKKKLAATPKKAKKPKTVKAKPV 168
Query: 304 KGS-GSKVVPAHLSRKTEAPKGPRK 327
K S K P K+ A + +K
Sbjct: 169 KASKPKKAKPVKPKAKSSAKRAGKK 193
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 55.1 bits (131), Expect = 9e-08
Identities = 45/205 (21%), Positives = 70/205 (34%), Gaps = 23/205 (11%)
Query: 129 PKHKKKIQPRKMA--PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKP 186
P+ K PR P P + G P P + + PP GK + P K Q P
Sbjct: 143 PQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGP 202
Query: 187 PPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSS 246
PP+ G + ++ G + Q G + PP P + P GG
Sbjct: 203 PPQ-GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG------------- 248
Query: 247 QGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGS 306
K + KP + G+ S + + K + P +G N + P G
Sbjct: 249 -------NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGG 301
Query: 307 GSKVVPAHLSRKTEAPKGPRKAGLP 331
+ A + + + P P + G P
Sbjct: 302 NPQQPQAPPAGQPQGPPRPPQGGRP 326
Score = 50.8 bits (120), Expect = 2e-06
Identities = 51/224 (22%), Positives = 72/224 (32%), Gaps = 32/224 (14%)
Query: 146 PRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAK 205
P G K +GP P + + PP K + P K Q PPP+ G + G +
Sbjct: 60 PPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQ 119
Query: 206 DTRAQSGEARKVPPKPDKAM---------RAPSSAGGLSRKAKAKGSRSSQGDAEAYRKT 256
Q G + PP P K R+P S G + +G QG K
Sbjct: 120 GPPPQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKP 179
Query: 257 K----------------AESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAA 300
+ + + P K ++ + P K + P+ G P
Sbjct: 180 QGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGK----PQGPPPQGGNQPQGPPP 235
Query: 301 APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344
P K G P K + P P K P SK S R+
Sbjct: 236 PPGKPQGP---PPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARS 276
Score = 45.1 bits (105), Expect = 1e-04
Identities = 45/198 (22%), Positives = 67/198 (33%), Gaps = 24/198 (12%)
Query: 146 PRRAGEAKGKG-PKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAA 204
P G K +G P P + + PP G + P K Q PPP QG +
Sbjct: 39 PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----------QGDKS 87
Query: 205 KDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSK 264
+ R+ G+ + PP+ + P G + +G QG + +
Sbjct: 88 RSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGP-----PPPGKPQGPP 142
Query: 265 PTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKG 324
P K ++ + P K + P+ G P P K G P +K + P
Sbjct: 143 PQGDKSRSPRSPPGK----PQGPPPQGGNQPQGPPPPPGKPQGP---PPQGGKKPQGPPP 195
Query: 325 PRKAGLPIKASSSKVSSQ 342
P K P SSQ
Sbjct: 196 PGKPQGPPPQGDKSRSSQ 213
>gi|4885373 histone cluster 1, H1a [Homo sapiens]
Length = 215
Score = 54.3 bits (129), Expect = 2e-07
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 20 SSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGEQRRGTSVAAIKL 79
+S +PE G + P G P V ++++A + ++R G S+AA+K
Sbjct: 11 ASAAPEKPLAGKKAKKPAKAAAASKKKPAG---PSVSELIVQAASSSKERGGVSLAALKK 67
Query: 80 YILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRK 139
+ DV + +K + + + +G L + +K GA+GSFKL K ++ +
Sbjct: 68 ALAAA--GYDVEKNNSRIKLGIKSLVSKGTLVQ---TKGTGASGSFKL-NKKASSVETKP 121
Query: 140 MAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKP---------PPKP 190
A A + K KK + G KK+ K P K +KP P KP
Sbjct: 122 GASKVATKTKATGASKKLKKAT---------GASKKSVKTPKKAKKPAATRKSSKNPKKP 172
Query: 191 GAA-TEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRA 227
+K K AK + ++ +AR PK K +A
Sbjct: 173 KTVKPKKVAKSPAKAKAVKPKAAKARVTKPKTAKPKKA 210
Score = 38.5 bits (88), Expect = 0.009
Identities = 54/203 (26%), Positives = 81/203 (39%), Gaps = 30/203 (14%)
Query: 160 PSEAKEDPPNVGKVKKAAKRPAKV----QKPPPKPGA------ATEKARKQGG----AAK 205
P+ A P K AK+PAK +K P P A ++++GG A K
Sbjct: 7 PAPAASAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALK 66
Query: 206 DTRAQSG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSK 264
A +G + K + +++ S G L + KG+ +S KA S +K
Sbjct: 67 KALAAAGYDVEKNNSRIKLGIKSLVSKGTL---VQTKGTGAS---GSFKLNKKASSVETK 120
Query: 265 PTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPK- 323
P ASKV TK K +K K G + K+ K + S+ + PK
Sbjct: 121 PGASKV------ATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKT 174
Query: 324 -GPRK-AGLPIKASSSKVSSQRA 344
P+K A P KA + K + +A
Sbjct: 175 VKPKKVAKSPAKAKAVKPKAAKA 197
Score = 38.5 bits (88), Expect = 0.009
Identities = 57/209 (27%), Positives = 78/209 (37%), Gaps = 37/209 (17%)
Query: 161 SEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGA------ATEKARKQGG----AAKDTRAQ 210
S A E P K KK AK A +K P P A ++++GG A K A
Sbjct: 12 SAAPEKPLAGKKAKKPAKAAAASKKKPAGPSVSELIVQAASSSKERGGVSLAALKKALAA 71
Query: 211 SG-EARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASK 269
+G + K + +++ S G L + KG+ +S KA S +KP ASK
Sbjct: 72 AGYDVEKNNSRIKLGIKSLVSKGTL---VQTKGTGAS---GSFKLNKKASSVETKPGASK 125
Query: 270 VKN-----GAASPTKK---------KVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHL 315
V GA+ KK K KAK P A + + P KV +
Sbjct: 126 VATKTKATGASKKLKKATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPA 185
Query: 316 SRKTEAPKGPR------KAGLPIKASSSK 338
K PK + K P KA+ K
Sbjct: 186 KAKAVKPKAAKARVTKPKTAKPKKAAPKK 214
Score = 35.4 bits (80), Expect = 0.076
Identities = 25/78 (32%), Positives = 38/78 (48%), Gaps = 6/78 (7%)
Query: 102 ATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPS 161
ATG + + P +K AT PK K ++P+K+A + A +AK P K +
Sbjct: 142 ATGASKKSVKTPKKAKKPAATRKSSKNPKKPKTVKPKKVAKSPA-----KAKAVKP-KAA 195
Query: 162 EAKEDPPNVGKVKKAAKR 179
+A+ P K KKAA +
Sbjct: 196 KARVTKPKTAKPKKAAPK 213
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 53.5 bits (127), Expect = 3e-07
Identities = 44/186 (23%), Positives = 82/186 (44%), Gaps = 12/186 (6%)
Query: 126 KLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQK 185
K++ + +++ + R +PA AP A A GP +++ + G+ K+AA + Q
Sbjct: 485 KILTQRRERYRQRSPSPAPAPAPAAAA---GPPTRKKSRRERKRSGEAKEAASSSSGTQP 541
Query: 186 PPPKPGAATE------KARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAK 239
PP P + + + RK G A + + +R + R+ G SR+++
Sbjct: 542 APPAPASPWDSKKHRSRDRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSR 601
Query: 240 AKGSRSSQGDAEAYRKTKAESKSSKPTA--SKVKNGAASPTKKKVVAKAKAPKAGQGPNT 297
++ R + + + + S SS+ K ++G S KKK ++G G +
Sbjct: 602 SREKRRRRRRSASPPPATSSSSSSRRERHRGKHRDGGGSKKKKKRSRSRGEKRSGDG-SE 660
Query: 298 KAAAPA 303
KA APA
Sbjct: 661 KAPAPA 666
Score = 38.1 bits (87), Expect = 0.012
Identities = 47/224 (20%), Positives = 76/224 (33%), Gaps = 33/224 (14%)
Query: 132 KKKIQPRKMAPATAPRRAGEAKGKGPK--------KPSEAKEDPPNVGKVKKAAKRPAKV 183
K + R+ + A + + KG K + + D K + K A
Sbjct: 745 KSSQKDRRRSGAASSSSSSREKGSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPS 804
Query: 184 QKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGS 243
PPPKP ++ G+ + + S +RKV + A+ + A +
Sbjct: 805 SGPPPKPPVSS-------GSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASA 857
Query: 244 RSSQGDAEAYRKTKAESKSSKPTA------SKVKNGAASPTKKKVVAKAKAPKAGQGPNT 297
+ R ++ S KP +K G+ P K KV AKA A K
Sbjct: 858 GLGSIGVKFSRDRESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKT------ 911
Query: 298 KAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSS 341
KG+ K P+ +K + G +G + SK S
Sbjct: 912 ------KGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKKSKADS 949
Score = 35.8 bits (81), Expect = 0.058
Identities = 33/163 (20%), Positives = 64/163 (39%), Gaps = 20/163 (12%)
Query: 177 AKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSR 236
A PA PP + + E RK+ G AK+ + S + PP P S SR
Sbjct: 504 APAPAAAAGPPTRKKSRRE--RKRSGEAKEAASSSSGTQPAPPAPASPW---DSKKHRSR 558
Query: 237 KAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPN 296
K SS + ++++ S + ++ + G + ++ + + + A P
Sbjct: 559 DRKPGSHASSSARRRSRSRSRSRSTRRRSRSTDRRRGGSRRSRSREKRRRRRRSASPPPA 618
Query: 297 TKAAAPAK----------GSGSKVVPAHLSRKTEAPKGPRKAG 329
T +++ ++ G GSK +K +G +++G
Sbjct: 619 TSSSSSSRRERHRGKHRDGGGSK-----KKKKRSRSRGEKRSG 656
Score = 35.8 bits (81), Expect = 0.058
Identities = 41/196 (20%), Positives = 75/196 (38%), Gaps = 19/196 (9%)
Query: 112 RPLNSKARGATGSFKLVPKHKKKIQP------RKMAPATAPRRAGEAKGKGPKKPSEAKE 165
+P S G++ S K K+Q R+ +T P + + G G +++
Sbjct: 810 KPPVSSGSGSSSSSSSCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRD 869
Query: 166 DPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAM 225
+K + P ++ K P + K AK T+ G+ + P K K +
Sbjct: 870 RESRSPFLKPDERAPTEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTK--PSKTRKKV 927
Query: 226 RAPSSAGGLSRKAKAKGSRS-SQGDAEAYRKTKAESKSSKPTASKVKN----------GA 274
R+ +GG + K S++ S A + + S S + A+KV + A
Sbjct: 928 RSGGGSGGSGGQVSLKKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPA 987
Query: 275 ASPTKKKVVAKAKAPK 290
+P + V + K P+
Sbjct: 988 LTPDSQTVDSSCKTPE 1003
Score = 30.0 bits (66), Expect = 3.2
Identities = 44/226 (19%), Positives = 79/226 (34%), Gaps = 28/226 (12%)
Query: 133 KKIQPRKMAPATAPRRAGEAKGKGPKK--------PSEAKEDPPNVGKVKKAAKRPAKVQ 184
KK + + A + A E G ++ P +A PP + + K
Sbjct: 943 KKSKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKTP 1002
Query: 185 KPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSR 244
+ P ATE+A +GGA ++ + E + + + +++ + + A +
Sbjct: 1003 EVSFLPEEATEEAGVRGGAEEEEEEEEEEEEEEEEEEQQPATTTATSTAAAAPSTAPSAG 1062
Query: 245 SSQGDAEAYRKTKAESKSSKPT------------ASKVKNGAASPT-------KKKVVAK 285
S+ GD+ A A S PT +G + T + + ++
Sbjct: 1063 STAGDSGA-EDGPASRVSQLPTLPPPMPWNLPAGVDCTTSGVLALTALLFKMEEANLASR 1121
Query: 286 AKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLP 331
AKA + Q N + S + PA + P GP LP
Sbjct: 1122 AKAQELIQATNQILSHRKPPSSLGMTPAPVPTSLGLPPGPSSYLLP 1167
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 52.8 bits (125), Expect = 5e-07
Identities = 53/233 (22%), Positives = 88/233 (37%), Gaps = 20/233 (8%)
Query: 129 PKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPN-VGKVKKAAKRPAKVQKPP 187
P K + P A + A + SE E P G K ++ +PA K P
Sbjct: 339 PPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSP 398
Query: 188 P-KPGAATEK---------ARKQGGAAKDTRAQSGEARKVPP--KPDKAMRAPSSAGGLS 235
KP AA ++ RK ++ + + S E K K +A L
Sbjct: 399 AVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLP 458
Query: 236 RKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKN---GAASPTKKKVVAKAKAPKAG 292
K +GSR S D+++ + E K+SK K G A+P+K K KA
Sbjct: 459 AKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKA---- 514
Query: 293 QGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAE 345
+ N+ ++ + + + S + +APK + L + + +S+ E
Sbjct: 515 ESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEE 567
Score = 50.1 bits (118), Expect = 3e-06
Identities = 47/174 (27%), Positives = 72/174 (41%), Gaps = 12/174 (6%)
Query: 179 RPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSR-K 237
+ AKV + + K K+ ++ D+ S E +V P K P+ GL K
Sbjct: 59 KSAKVPERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGK 118
Query: 238 AKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNT 297
A AK S SS + E+ E + +P VK P K A K K+ +
Sbjct: 119 AAAKASESSSSE-ESSDDDDEEDQKKQPVQKGVK-----PQAKAAKAPPKKAKSSDSDSD 172
Query: 298 KAAA--PAKGSGSKVVPAHLSRKTEAPKGPRKAGLPI---KASSSKVSSQRAEA 346
++ P K K+ P + +T+AP P +A I KA+SS SS + +
Sbjct: 173 SSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSS 226
Score = 47.8 bits (112), Expect = 1e-05
Identities = 62/241 (25%), Positives = 85/241 (35%), Gaps = 44/241 (18%)
Query: 133 KKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQK------- 185
KK P+K A AP +A P + S + ED + ++ K+P K +
Sbjct: 240 KKTVPKKQVVAKAPVKAATT----PTRKSSSSEDSSS--DEEEEQKKPMKNKPGPYSSVP 293
Query: 186 ----PPPKPGAATEKARK---------QGGAAKDTRAQSGEARKVPPKP---DKAMRAPS 229
PPPK T+ +K + D S E K PP KA P
Sbjct: 294 PPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPP 353
Query: 230 SAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAP 289
A KA S S D+++ +A SK + T + N A TK V A AP
Sbjct: 354 PA------KKAAESSSDSSDSDSSEDDEAPSKPAGTTKNS-SNKPAVTTKSPAVKPAAAP 406
Query: 290 KAGQGPNTKAAAPAKGSGSKVVPAHLSRK--------TEAPKGPRKAGLPIKASSSKVSS 341
K G K S S + S + T PK KA L + A + S
Sbjct: 407 KQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGS 466
Query: 342 Q 342
+
Sbjct: 467 R 467
Score = 46.6 bits (109), Expect = 3e-05
Identities = 58/229 (25%), Positives = 89/229 (38%), Gaps = 34/229 (14%)
Query: 132 KKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPG 191
++K+Q A ++A + + + E + PP KKAA +V PP K
Sbjct: 65 ERKLQANGPVAKKAKKKASSSDSEDSSEEEEEVQGPP----AKKAAVPAKRVGLPPGKAA 120
Query: 192 AAT--------------EKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRK 237
A E+ +K+ K + Q+ +A K PPK KA + S + S
Sbjct: 121 AKASESSSSEESSDDDDEEDQKKQPVQKGVKPQA-KAAKAPPK--KAKSSDSDSDSSSED 177
Query: 238 AKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNT 297
K + +TKA K ++ A K+ NG A+ + + + + +
Sbjct: 178 EPPKNQKPKITPVTVKAQTKAPPKPAR-AAPKIANGKAASSSS---SSSSSSSSDDSEEE 233
Query: 298 KAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAG-LPIKASSSKVSSQRAE 345
KAAA K K VP +K K P KA P + SSS S E
Sbjct: 234 KAAATPK----KTVP----KKQVVAKAPVKAATTPTRKSSSSEDSSSDE 274
Score = 42.4 bits (98), Expect = 6e-04
Identities = 59/256 (23%), Positives = 95/256 (37%), Gaps = 27/256 (10%)
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAP-RRAGEAKGKGPKKPSEAKEDPPNVG 171
P N K + + K K K P + AP A + A + S+ E+
Sbjct: 180 PKNQKPKITPVTVKAQTKAPPK--PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAA 237
Query: 172 KVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVP----PKPDKAMRA 227
KK + V K P K AAT RK +++D+ + E +K P P P ++
Sbjct: 238 TPKKTVPKKQVVAKAPVK--AATTPTRKSS-SSEDSSSDEEEEQKKPMKNKPGPYSSVPP 294
Query: 228 PSS-----AGGLSRKAKAKGSR---SSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTK 279
PS+ + G KA + S D+ + +E + PT + V P
Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP 354
Query: 280 KKVVAKAKAPKAGQGPNTKAAAPAKGSG----SKVVPAHLSRK-----TEAPKGPRKAGL 330
K A++ + + + AP+K +G S PA ++ APK P G
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVGGGQ 414
Query: 331 PIKASSSKVSSQRAEA 346
+ + SS E+
Sbjct: 415 KLLTRKADSSSSEEES 430
Score = 40.8 bits (94), Expect = 0.002
Identities = 88/372 (23%), Positives = 132/372 (35%), Gaps = 36/372 (9%)
Query: 3 PGSVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEA 62
P +S SS+ + P KPGP + VPP +G + P + +E
Sbjct: 260 PTRKSSSSEDSSSDEEEEQKKPMKNKPGP-YSSVPPPSAPPPKKSLGTQPP---KKAVEK 315
Query: 63 LQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLN------- 115
Q E +S + K P + K K A +
Sbjct: 316 QQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDE 375
Query: 116 --SKARGATGSFKLVPKHKKKIQPRKMAPATAPRR--AGEAKGKGPKKPSEAKEDPPNVG 171
SK G T + P K K PA AP++ G K K S + E+ +
Sbjct: 376 APSKPAGTTKNSSNKPAVTTKSPAVK--PAAAPKQPVGGGQKLLTRKADSSSSEEESSSS 433
Query: 172 KVKKAAKRPAKVQKPPPKPGAATEKARKQG-----GAAKDTRAQSGEARK-------VPP 219
+ +K K A KP AA KQ ++ D+ + S E + V
Sbjct: 434 EEEKTKKMVATT-KPKATAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVKK 492
Query: 220 KPDK-AMRAPSSAGGLSRKAKAKGSRSSQG-DAEAYRKTKAESKSSKPTASKVKNGAASP 277
KP K A A S ++K KA+ S SS D+ + K + K S + NG ++
Sbjct: 493 KPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSAL 552
Query: 278 TKKKVVAKAKAPKAGQGPNTKAAAPAKGSGS--KVVPAHLSRKTEAPKGPR-KAGLPIKA 334
T + A AK + + KAA SGS K +++ E P+ + K P
Sbjct: 553 TAQNGKA-AKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIKLQTPNTF 611
Query: 335 SSSKVSSQRAEA 346
K +RA +
Sbjct: 612 PKRKKGEKRASS 623
>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
sapiens]
Length = 870
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/234 (23%), Positives = 88/234 (37%), Gaps = 33/234 (14%)
Query: 111 ARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPR-------RAGEAKGKGPKKPSEA 163
ARP ++ARG G L P +++ +P PAT P+ + A G+ P P
Sbjct: 636 ARP--ARARGEIGGLSLSPSPERR-KPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPG 692
Query: 164 KEDPPNVGKVKKAAKRPA---------KVQKPPPKPGAATEKARKQGGAAKDTRAQSGEA 214
E P+ K K+ + + + P P+P E+A + A
Sbjct: 693 SEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEA-------------TALA 739
Query: 215 RKVPPKPD-KAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNG 273
PP+ +A P A G R + +S A+ KT++ ++ ++
Sbjct: 740 APSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPRE 799
Query: 274 AASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRK 327
+P +K + A A P T+ P K + P +KT K PRK
Sbjct: 800 KPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRK 853
>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
sapiens]
Length = 865
Score = 51.6 bits (122), Expect = 1e-06
Identities = 54/234 (23%), Positives = 88/234 (37%), Gaps = 33/234 (14%)
Query: 111 ARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPR-------RAGEAKGKGPKKPSEA 163
ARP ++ARG G L P +++ +P PAT P+ + A G+ P P
Sbjct: 631 ARP--ARARGEIGGLSLSPSPERR-KPPPPDPATKPKVSWIHGKHSAAAAGRAPSPPPPG 687
Query: 164 KEDPPNVGKVKKAAKRPA---------KVQKPPPKPGAATEKARKQGGAAKDTRAQSGEA 214
E P+ K K+ + + + P P+P E+A + A
Sbjct: 688 SEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEA-------------TALA 734
Query: 215 RKVPPKPD-KAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNG 273
PP+ +A P A G R + +S A+ KT++ ++ ++
Sbjct: 735 APSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTRSLGRAEVALGAQGPRE 794
Query: 274 AASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRK 327
+P +K + A A P T+ P K + P +KT K PRK
Sbjct: 795 KPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAPETPRKKTPIQKPPRK 848
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 51.6 bits (122), Expect = 1e-06
Identities = 73/378 (19%), Positives = 137/378 (36%), Gaps = 53/378 (14%)
Query: 3 PGSVTSDISPSSTSTAGSSR----SPESEKPGPSHG----------------GVPPGGPS 42
P S +S+ SP S SR SPES KP P+ G G S
Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKS 472
Query: 43 HSSLP---VGRRHPPVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQ 99
HS P +GR P + +RG S + + + R + ++
Sbjct: 473 HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSR-SAQRWGRSRSPQRR 531
Query: 100 ALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKK 159
+ +R +R N++ RG + S + H + R + + P R G ++ + P +
Sbjct: 532 GRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPAR 591
Query: 160 PSEAKEDPPNV------------GKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDT 207
P + + A+R ++ + P + + AR+ G + T
Sbjct: 592 RRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRT 651
Query: 208 RAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKS----- 262
A+ G +R P R+ + A R +R + + R+ ++ S+S
Sbjct: 652 PARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG 711
Query: 263 ---SKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKT 319
S+ + ++G++S K K + ++ P K + + + SR
Sbjct: 712 RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR---------ISSRRSRSL 762
Query: 320 EAPKGPRKAGLPIKASSS 337
+P+ K+ L ++ S S
Sbjct: 763 SSPRSKAKSRLSLRRSLS 780
Score = 50.1 bits (118), Expect = 3e-06
Identities = 52/242 (21%), Positives = 91/242 (37%), Gaps = 16/242 (6%)
Query: 116 SKARGATGSFKLVPKHKKKIQPR---KMAPATAPRRAGEAKGKGPKKPSEAKE------- 165
S R ++ S PK KKK + + + + +++PRR + K K SE++
Sbjct: 172 SLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRS 231
Query: 166 -DPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDT-RAQSGEARKVPPKPDK 223
P + K K ++ ++ P PK A ++ DT R++S A
Sbjct: 232 PTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTAL 291
Query: 224 AMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVV 283
A R+PS A G R+ + S G R + E+ + +P++ K
Sbjct: 292 AGRSPSPASG--RRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATR 349
Query: 284 AKAKAPKAGQGPNTKAAAP--AKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSS 341
++ GP A P A+ G P + ++ P P P + S S
Sbjct: 350 PSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSP 409
Query: 342 QR 343
++
Sbjct: 410 EK 411
Score = 46.2 bits (108), Expect = 4e-05
Identities = 39/202 (19%), Positives = 80/202 (39%), Gaps = 5/202 (2%)
Query: 129 PKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPP 188
PK K + PR+ + ++P +A+ ++ A P + +R V P P
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLS--RRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735
Query: 189 KPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQG 248
+ + + R+ + + T+ S R PKP R+ S + + + RS
Sbjct: 1736 AEKSRSSRRRRSASSPR-TKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSS 1794
Query: 249 DAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGS 308
+ + R+ ++ S+S + +G S + + + + + +G + K S S
Sbjct: 1795 QSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRS 1854
Query: 309 KVVPA--HLSRKTEAPKGPRKA 328
+ PA SR +P R++
Sbjct: 1855 RTSPAPWKRSRSRASPATHRRS 1876
Score = 45.1 bits (105), Expect = 1e-04
Identities = 72/333 (21%), Positives = 129/333 (38%), Gaps = 33/333 (9%)
Query: 18 AGSSRSPESEKPGPSHGGVPPGGPSHSSLPV--GRRHPPVLRMVLEALQAGEQRRGTSVA 75
+G SRS + G S P G S S V GR H + + + E R+ S
Sbjct: 678 SGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSE-RKNKSRT 736
Query: 76 AIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKI 135
+ + + P + R ++L++ + A+ S R +GS PK K +
Sbjct: 737 SQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK---AKSRLSLRRSLSGSSPC-PKQKSQT 792
Query: 136 QPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATE 195
PR+ ++ +A K + P + S + PP K K +++ P PK + T
Sbjct: 793 PPRRSRSGSSQPKA---KSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP 849
Query: 196 KARKQGGAAKDTRAQSGEARKVP---------PKPDKAMRAPS--SAGGLSRKAKAKGSR 244
+QG T Q+ E P P P+ R PS S G S + K S
Sbjct: 850 P--RQGSI---TSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG-SSPPRVKSST 903
Query: 245 SSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAK 304
+ + + K+ + +G++SP+ +V ++ P+ +++ +P
Sbjct: 904 PPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRT-TPR-----RSRSVSPCS 957
Query: 305 GSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSS 337
S+++P + + +P K P + S S
Sbjct: 958 NVESRLLPRYSHSGSSSPDTKVKPETPPRQSHS 990
Score = 45.1 bits (105), Expect = 1e-04
Identities = 51/232 (21%), Positives = 87/232 (37%), Gaps = 27/232 (11%)
Query: 11 SPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVG-----RRHPPVLRMVLEALQA 65
S SS+S++ SS S S S G SSLPV +R P EA++
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Query: 66 GEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSF 125
G T P R + ++ + +S + ++ S
Sbjct: 2593 GRPPEPT-------------PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2639
Query: 126 KLVPKHKKKIQPRKMAPATAPRRA-------GEAKGKGPKKPSEAKEDPPNVGKVKKAAK 178
P K P P+ A GE + + P+KP ++ D ++ +
Sbjct: 2640 SSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERR 2699
Query: 179 RPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSS 230
RP+ P + +++E+ ++G D+R+ S + R+ P P + MR SS
Sbjct: 2700 RPSPQPSPRDQQSSSSERGSRRGQRG-DSRSPSHKRRRETPSP-RPMRHRSS 2749
Score = 41.2 bits (95), Expect = 0.001
Identities = 43/195 (22%), Positives = 81/195 (41%), Gaps = 21/195 (10%)
Query: 113 PLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPR-----RAGEAKGKGPKKPSEAKEDP 167
PL ++R +GS V K ++ PR+ ++P RA G E K
Sbjct: 1572 PLRQRSR--SGSSPEVDS-KSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 168 PNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTR--AQSGEARKVPPKPDKAM 225
P + + +K + P P+ ++TE + + ++ R ++S K +
Sbjct: 1629 PRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRR 1688
Query: 226 RAPSSAGGLSRKAK-AKGSRSSQGDAEAYRKTKAESKSS----------KPTASKVKNGA 274
R+ S+ L+RKA+ ++ SRS+ E +T + S K +S+ + A
Sbjct: 1689 RSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSA 1748
Query: 275 ASPTKKKVVAKAKAP 289
+SP K + ++P
Sbjct: 1749 SSPRTKTTSRRGRSP 1763
Score = 39.3 bits (90), Expect = 0.005
Identities = 40/187 (21%), Positives = 69/187 (36%), Gaps = 22/187 (11%)
Query: 131 HKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKP--PP 188
++ K + +K AT P + E GP+ P+ G + Q+P PP
Sbjct: 335 YEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPP 394
Query: 189 KPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQG 248
+ T K ++ S E+ P+P K R SS+ + A A GS
Sbjct: 395 SEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSH---- 450
Query: 249 DAEAYRKTKAESKSSKPTASKVKNGAA------SPTKKKVVAKAKAPKAGQGPNTKAAAP 302
SS PT+ +G A S T + + ++++P + +++ P
Sbjct: 451 ----------REISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTP 500
Query: 303 AKGSGSK 309
K S+
Sbjct: 501 TKRGHSR 507
Score = 38.1 bits (87), Expect = 0.012
Identities = 72/336 (21%), Positives = 109/336 (32%), Gaps = 18/336 (5%)
Query: 1 MAPGSVTSDISPSSTSTAGSSRSPES---EKPGPSHGGVPPGGPSHSSLPVGRRHPPV-L 56
M+P + SP GSSR+P S + G G P P H V H +
Sbjct: 2122 MSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRI 2181
Query: 57 RMVLEALQAGEQRRGTSVAAIKLYI-LHKYPTVDVLRFKYLLKQALATGMRRGLLARPLN 115
+ L A+ G R S++A L + + P L +L T L +R
Sbjct: 2182 ALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPL-------MSLRTAPAANLASRIPA 2234
Query: 116 SKARG---ATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGK 172
+ A A+ +P R A A A A P + A P
Sbjct: 2235 ASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPA 2294
Query: 173 VKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAG 232
V A R G+ T ++ T A V P+ A + AG
Sbjct: 2295 VNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354
Query: 233 GLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASP---TKKKVVAKAKAP 289
+ A A S +S A A S +A + +G SP + + AP
Sbjct: 2355 SRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAP 2414
Query: 290 KAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGP 325
+ + +A +P+ G + L + P+ P
Sbjct: 2415 SQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSP 2450
Score = 36.2 bits (82), Expect = 0.044
Identities = 27/112 (24%), Positives = 49/112 (43%), Gaps = 10/112 (8%)
Query: 202 GAAKDTRAQSGEARKVPPKPDK---------AMRAPSSAGGLSRKAKAKGSRSSQGDAEA 252
G++ D + ++ EA++ P+P K + R+P+ +K K +G RS
Sbjct: 148 GSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRR 207
Query: 253 YRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAK 304
RK ++ K + + K SPT K K+K K + +T A ++
Sbjct: 208 ERKKSSKKKKHRSESESKKRKHRSPTPKS-KRKSKDKKRKRSRSTTPAPKSR 258
Score = 36.2 bits (82), Expect = 0.044
Identities = 70/361 (19%), Positives = 128/361 (35%), Gaps = 53/361 (14%)
Query: 14 STSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPP--VLRMVLEALQAGEQRRG 71
S +T G SRS + G S P S S P RR R + +RR
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
Query: 72 TSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKH 131
+ + ++ + P RR +R RG + S P
Sbjct: 626 RTRSPVRRRSRSRSPA------------------RRSGRSRSRTPARRGRSRS--RTPAR 665
Query: 132 KKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAA--KRPAKVQKPPPK 189
+ + + R T RR+G ++ + P + ++ P G+ + + +R + P +
Sbjct: 666 RGRSRSR-----TPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQR 720
Query: 190 ---PGAATEKARKQGGAAKDTRAQSGEARK---VPPKPDKAMRAPSSAGG--LSRKAKAK 241
G+++E+ K + + +R+ S K + + +++ +P S LS +
Sbjct: 721 RGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS 780
Query: 242 GS-------------RSSQGDAEAYRKTKA---ESKSSKPTASKVKNGAASPTKKKVVAK 285
GS RS G ++ K++ S+SS K K+ S +
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840
Query: 286 AKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAE 345
K+G P + + + V P S +P K+ P + S S S R +
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVK 900
Query: 346 A 346
+
Sbjct: 901 S 901
Score = 35.0 bits (79), Expect = 0.099
Identities = 69/326 (21%), Positives = 113/326 (34%), Gaps = 29/326 (8%)
Query: 37 PPGGPSHSSLPVGRRHPPVLRMVLEALQ-----AGEQRRGTSVAAI----KLYILHKYPT 87
PP PS S + R P RM Q A +Q R +A + I P
Sbjct: 2410 PPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTP- 2468
Query: 88 VDVLRFKYLLKQALAT-----GMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAP 142
V + L A+AT G G+L+ P G P QP +A
Sbjct: 2469 --VAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGE---PPASTGAQQPSALAA 2523
Query: 143 AT-APRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201
A R + S + + ++ ++ P +P A ++
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583
Query: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESK 261
A K+ E R P P K R SS+ S + + S SS + + + + S
Sbjct: 2584 PAPKEAVR---EGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSS 2637
Query: 262 SSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEA 321
SS ++S + + + + + K +PK ++ +P K S LS
Sbjct: 2638 SSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVE 2697
Query: 322 PKGPRKAGLP--IKASSSKVSSQRAE 345
+ P P ++SSS+ S+R +
Sbjct: 2698 RRRPSPQPSPRDQQSSSSERGSRRGQ 2723
Score = 33.1 bits (74), Expect = 0.38
Identities = 42/205 (20%), Positives = 71/205 (34%), Gaps = 24/205 (11%)
Query: 151 EAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQ 210
E K + P + S + PP V + P++ P PK A ++ +
Sbjct: 880 ELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPS 939
Query: 211 SGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKV 270
+R P + R+ S + + + S S + K + + S
Sbjct: 940 RVTSRTTP----RRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQS------- 988
Query: 271 KNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVV---PAHLSR----KTEAPK 323
+G+ SP K KA+ P +K+ P + S +V P LS K+ P
Sbjct: 989 HSGSISPYPK---VKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP 1045
Query: 324 GPRKAG---LPIKASSSKVSSQRAE 345
G G L +K S R++
Sbjct: 1046 GESYFGVSSLQLKGQSQTSPDHRSD 1070
Score = 30.8 bits (68), Expect = 1.9
Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 3/60 (5%)
Query: 5 SVTSDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQ 64
S +S S SS+S++ SS SP KPGP P S P G R R +++L+
Sbjct: 2630 SSSSSSSSSSSSSSSSSSSPSPAKPGPQ---ALPKPASPKKPPPGERRSRSPRKPIDSLR 2686
>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
Length = 819
Score = 51.2 bits (121), Expect = 1e-06
Identities = 64/261 (24%), Positives = 110/261 (42%), Gaps = 27/261 (10%)
Query: 99 QALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKG-KGP 157
+A A G +RG + + G K + KK + + A R G+ KG +
Sbjct: 334 KAAAAGTKRGGGGQQ-KAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREA 392
Query: 158 KKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTR---AQSGEA 214
K+ + ++ P ++A K PA + G ++K R++G A +R ++SG
Sbjct: 393 KRRGDGRKKPRWQNPRRRAQKAPAAKPR-----GGGSKKPRRRGPKAAKSRGGKSRSGGG 447
Query: 215 RKVPPKPDKAMRAPSSAGGLSRK--------AKAKGSRSSQGDAEAY-------RKTKAE 259
+K + KA + + AG SR A A G++S G +++ R KAE
Sbjct: 448 KKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAE 507
Query: 260 SKSSKPTASKVKN-GAASPTKKK-VVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSR 317
+ K TA+ K+ G P ++K VA AK+ G + A A G+ S +
Sbjct: 508 AAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQS 567
Query: 318 KTEAPKGPRKAGLPIKASSSK 338
+ PR+ G A+ ++
Sbjct: 568 RGGGGNKPRQWGQTAAAAKTR 588
Score = 45.4 bits (106), Expect = 7e-05
Identities = 53/210 (25%), Positives = 81/210 (38%), Gaps = 40/210 (19%)
Query: 130 KHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK 189
+ KK +P+ A RR G GK P+K + GK + R
Sbjct: 221 RRKKHRRPKPAAGGAKSRRGG---GKKPQKQRRRGQKAATGGKSRVGKSR---------- 267
Query: 190 PGAATEKARKQG------GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGS 243
G +K R+QG GA + A +GE P + R P S GG +
Sbjct: 268 -GGGDKKLRRQGQNAALAGAKRRGAATAGEK---PAAKGRGGRGPKSLGG-------QNP 316
Query: 244 RSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVV---AKAKAPKAGQGPN---- 296
R +G + R+ + K++K A+ K G K VV ++ K + G+ P
Sbjct: 317 RWGRGGKKPRRRGQ---KATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKA 373
Query: 297 TKAAAPAKGSGSKVVPAHLSRKTEAPKGPR 326
+ A A ++G G K R+ + K PR
Sbjct: 374 SAAGAKSRGGGDKKGLREAKRRGDGRKKPR 403
Score = 42.7 bits (99), Expect = 5e-04
Identities = 59/242 (24%), Positives = 89/242 (36%), Gaps = 48/242 (19%)
Query: 136 QPRKMAPATAPRRAGEAKGKGPKKP----SEAKEDPPNVGKVKKAAKRPAKVQKPPPKPG 191
+PR+ P A R G+++ G KKP +A++ G + K+ + K
Sbjct: 426 KPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGR-----QKAS 480
Query: 192 AATEKARKQGGAAKD-------TRAQSGEA--------------RKVPPKPDKAMRAPSS 230
AA K+R GG K R Q EA RK P + A+ S
Sbjct: 481 AAGTKSR--GGGLKSHSGKNLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKS 538
Query: 231 AGGLSR-----KAKAKGSRSSQGDAEAYRK----TKAESKSSKPTASKVKNGA-ASPTKK 280
G S+ KA A G+ S G + K A+K + G P +
Sbjct: 539 RVGGSKSRQRQKAVAAGATSHGGGGNKQSRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQ 598
Query: 281 KVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVS 340
K A ++G G A G+G+K SRK +G + A KA ++ +
Sbjct: 599 KAAAGVTKSRSGDGGKKAWRQKAAGTGAK------SRKKPWRRGQKDAAAAEKAWATGAT 652
Query: 341 SQ 342
S+
Sbjct: 653 SR 654
Score = 41.2 bits (95), Expect = 0.001
Identities = 49/211 (23%), Positives = 80/211 (37%), Gaps = 32/211 (15%)
Query: 115 NSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKE--------- 165
N ++RG G+ +PR+ A A + +G G K+P K
Sbjct: 564 NKQSRGGGGN-----------KPRQWGQTAA---AAKTRGGGDKQPGWQKAAAGVTKSRS 609
Query: 166 -DPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKA 224
D +KAA AK +K P + G A ++ A T SG + KP A
Sbjct: 610 GDGGKKAWRQKAAGTGAKSRKKPWRRGQKDAAAAEKAWATGATSRGSGGKQPRWQKPAAA 669
Query: 225 MRAPSSAGGLSRKAKAK--------GSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAAS 276
S+A + ++A+A+ SR G A + + KP K + G +
Sbjct: 670 GSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGA 729
Query: 277 PTKKKVVAKAKAPKAGQGPNTKAAAPAKGSG 307
++ AK++ + + K AA +K G
Sbjct: 730 KSRGSGGAKSRGSGGAKSRSGKKAAASKSHG 760
Score = 36.2 bits (82), Expect = 0.044
Identities = 54/249 (21%), Positives = 84/249 (33%), Gaps = 33/249 (13%)
Query: 108 GLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDP 167
G R KAR + KK +K + A R G K K +
Sbjct: 447 GKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKA 506
Query: 168 PNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRA 227
G+ AA ++ +K P + A A+ + G +K + Q A +
Sbjct: 507 EAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQ 566
Query: 228 PSSAGG--------LSRKAKAKG-----------------SRSSQGDAEAYRK----TKA 258
GG + AK +G SRS G +A+R+ T A
Sbjct: 567 SRGGGGNKPRQWGQTAAAAKTRGGGDKQPGWQKAAAGVTKSRSGDGGKKAWRQKAAGTGA 626
Query: 259 ESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRK 318
+S+ KP K+ AA+ +K A + G + PA A + ++
Sbjct: 627 KSR-KKPWRRGQKDAAAA---EKAWATGATSRGSGGKQPRWQKPAAAGSESSAAAAVGQE 682
Query: 319 TEAPKGPRK 327
EA K PR+
Sbjct: 683 AEARKKPRR 691
Score = 35.8 bits (81), Expect = 0.058
Identities = 57/244 (23%), Positives = 85/244 (34%), Gaps = 25/244 (10%)
Query: 121 ATGSFKLVPKHKKKIQPRKMAPATAPRR--------AG-EAKGKGPKKPSEAKEDPPNVG 171
A K++ KK++ +K A R AG EA+ K + G
Sbjct: 45 AAAGVKILGSGDKKLRRQKAAAGGKKARLRGQKGAVAGKEARQHWQKAAGAGGAENRGGG 104
Query: 172 KVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSA 231
+ K AA + KP +KA G RAQ A + A +A ++A
Sbjct: 105 EQKAAAAGTKSLGGRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAA 164
Query: 232 GGLS------RKAKAKGSRSSQGDAEAYRKTKA---ESKSSKPTASKVKNGAASPTKKKV 282
G S +KA A G++S G R K+ E K + +K + G ++K
Sbjct: 165 GVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRK- 223
Query: 283 VAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQ 342
K + PK G A +G G K + A G + G K+ Q
Sbjct: 224 --KHRRPKPAAG----GAKSRRGGGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLRRQ 277
Query: 343 RAEA 346
A
Sbjct: 278 GQNA 281
Score = 32.7 bits (73), Expect = 0.49
Identities = 41/164 (25%), Positives = 55/164 (33%), Gaps = 17/164 (10%)
Query: 136 QPRKMAPATAPRRAGEAKGKGP-----KKPSEAKEDPPNVGKVKKAA-----KRPAKVQK 185
QPR PA A + A G KKP + G A +R K +
Sbjct: 660 QPRWQKPAAAGSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPR 719
Query: 186 PPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRS 245
G K+R GGA SG A+ K A ++ G R+ SRS
Sbjct: 720 LGKSRGGGGAKSRGSGGAKS---RGSGGAKSRSGKKAAASKSHGGGGAKRRRGGGAKSRS 776
Query: 246 SQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAP 289
+ A + A + KP K + G +K A K P
Sbjct: 777 GEKAVTAGGQKAAAAGGKKPPRVKSRGGRG----QKAAAGGKKP 816
>gi|21361272 myeloid/lymphoid or mixed-lineage leukemia (trithorax
homolog, Drosophila); translocated to, 1 [Homo sapiens]
Length = 559
Score = 50.8 bits (120), Expect = 2e-06
Identities = 43/212 (20%), Positives = 86/212 (40%), Gaps = 16/212 (7%)
Query: 126 KLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKR------ 179
K P H K ++ + + P + + + P+K SE+K + + + + +
Sbjct: 174 KTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKL 233
Query: 180 -----PAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGL 234
P + + PPPK K + + T + G PP P + + P++A
Sbjct: 234 GEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSP 293
Query: 235 SRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQG 294
AK + SS+G A + S SS + K +S +KV A+++ +A +
Sbjct: 294 KPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKA 353
Query: 295 -----PNTKAAAPAKGSGSKVVPAHLSRKTEA 321
N++ A K ++ P++ S +++
Sbjct: 354 LEVEESNSEDEASFKSESAQSSPSNSSSSSDS 385
Score = 40.8 bits (94), Expect = 0.002
Identities = 43/196 (21%), Positives = 71/196 (36%), Gaps = 13/196 (6%)
Query: 157 PKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARK 216
P P A DP K +K K KP T++ R++ ++++ S E +
Sbjct: 162 PTIPLSAFSDPKKT-KPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELER 220
Query: 217 VPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAAS 276
K K G L ++ KA ++ A+++ K K +K ++ K G
Sbjct: 221 EQAKSSKDTSRKLGEGRLPKEEKAPPPKA------AFKEPKMALKETKLESTSPKGGPPP 274
Query: 277 P------TKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKAGL 330
P K A A +PK K+++ S P S + + K P K
Sbjct: 275 PPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKS 334
Query: 331 PIKASSSKVSSQRAEA 346
+ K S+ EA
Sbjct: 335 STRGEKVKAESEPREA 350
Score = 37.0 bits (84), Expect = 0.026
Identities = 36/159 (22%), Positives = 62/159 (38%), Gaps = 19/159 (11%)
Query: 128 VPKHKKKIQPR------KMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPA 181
+PK +K P+ KMA + KG P P PP + ++KRPA
Sbjct: 238 LPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPP----PP-----RASSKRPA 288
Query: 182 KVQKPPP----KPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRK 237
P P + ++++ +R G + T + S + K P K + R +
Sbjct: 289 TADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPR 348
Query: 238 AKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAAS 276
K + ++E K+ES S P+ S + ++S
Sbjct: 349 EAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSS 387
>gi|239753329 PREDICTED: hypothetical protein XP_002345623 [Homo
sapiens]
Length = 351
Score = 50.8 bits (120), Expect = 2e-06
Identities = 43/172 (25%), Positives = 71/172 (41%), Gaps = 11/172 (6%)
Query: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQG 201
P ++A +++G G KKP K K +K +R + K A+ +G
Sbjct: 145 PRRRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRG 204
Query: 202 GAAKDTRAQSGEARKVPPKPDKAMRAPSSAGG----LSRKAKAKGSRSSQGDAEAYRKTK 257
G K T A G+ P+ + +A S GG L R+ A S+GD + R K
Sbjct: 205 GGGKKTAAAGGKK----PRRRRGQKAAKSRGGGDKKLERQKAALTGVKSRGDKKPLRGGK 260
Query: 258 AESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSK 309
+ + + T S+ G +K A AK+ + G+G + A +G +
Sbjct: 261 KQRERGQNTKSR--GGGGEKPQKAAAAGAKS-RGGRGEKPQKAEAGQGQNRR 309
Score = 38.1 bits (87), Expect = 0.012
Identities = 55/241 (22%), Positives = 94/241 (39%), Gaps = 29/241 (12%)
Query: 89 DVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRR 148
++L LL++ G L + P+ S L P ++ +Q +A A +P R
Sbjct: 40 ELLELPALLQRPAGRGPCATLRSHPITPAPALLLLSHSL-PAQRRSMQAT-VAKAGSPGR 97
Query: 149 AGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTR 208
GK P++ P + A++ ++V + P+ +GG K R
Sbjct: 98 G--RLGKEPRRRESWTRSAPRRCPYQDASRAGSRVCRSRPQ---------NRGGGDKKPR 146
Query: 209 AQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTAS 268
+ +A K K R +AG ++K + R + A +K + K A+
Sbjct: 147 RRGQKAAKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQ------KAAAA 200
Query: 269 KVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKA 328
K + G KK A K P+ +G + AA ++G G K L R+ A G +
Sbjct: 201 KSRGGGG---KKTAAAGGKKPRRRRG---QKAAKSRGGGDK----KLERQKAALTGVKSR 250
Query: 329 G 329
G
Sbjct: 251 G 251
Score = 31.2 bits (69), Expect = 1.4
Identities = 38/151 (25%), Positives = 58/151 (38%), Gaps = 11/151 (7%)
Query: 200 QGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAE 259
+G K+ R + R P + + S AG SR +++ GD + R+ +
Sbjct: 97 RGRLGKEPRRRESWTRSAPRRCP--YQDASRAG--SRVCRSRPQNRGGGDKKPRRRGQKA 152
Query: 260 SKS-----SKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPA-KGSGSKVVPA 313
+KS KP K A +K +A AG KAAA +G G K A
Sbjct: 153 AKSRGGGGKKPRGQKAAGAGAKKHRKPRRRGERAAAAGGKKLQKAAAAKSRGGGGKKTAA 212
Query: 314 HLSRKTEAPKGPRKAGLPIKASSSKVSSQRA 344
+K +G +KA K+ Q+A
Sbjct: 213 AGGKKPRRRRG-QKAAKSRGGGDKKLERQKA 242
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 50.1 bits (118), Expect = 3e-06
Identities = 66/241 (27%), Positives = 96/241 (39%), Gaps = 46/241 (19%)
Query: 116 SKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKK 175
+K+RG T L+PK + Q R + K G +P E + P G
Sbjct: 375 TKSRGLT---PLLPKSTIQEQERHK----------QLKSAGIARPEEGR--PVVSGTGND 419
Query: 176 AAKRPAKVQKPPP----KPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSA 231
P K P P KP A T+ A+ AK + +P +P AP++
Sbjct: 420 ITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT------QPTSLPKQP-----APTTI 468
Query: 232 GGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKA 291
GGL++K + S G A + S++P+ K+ K K +A AKAP+
Sbjct: 469 GGLNKKPMSLAS----GLVPAAPPKRPAVASARPSILPSKD-----VKPKPIADAKAPEK 519
Query: 292 GQGPNTKAAAPAKGSGSK---VVPAHLSRKTEAPKGPRKAG----LPIKASSSKVSSQRA 344
P+ A+APA SGSK V + A GP LP K ++ K + A
Sbjct: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
Query: 345 E 345
E
Sbjct: 580 E 580
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 50.1 bits (118), Expect = 3e-06
Identities = 66/241 (27%), Positives = 96/241 (39%), Gaps = 46/241 (19%)
Query: 116 SKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKK 175
+K+RG T L+PK + Q R + K G +P E + P G
Sbjct: 375 TKSRGLT---PLLPKSTIQEQERHK----------QLKSAGIARPEEGR--PVVSGTGND 419
Query: 176 AAKRPAKVQKPPP----KPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSA 231
P K P P KP A T+ A+ AK + +P +P AP++
Sbjct: 420 ITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKT------QPTSLPKQP-----APTTI 468
Query: 232 GGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKA 291
GGL++K + S G A + S++P+ K+ K K +A AKAP+
Sbjct: 469 GGLNKKPMSLAS----GLVPAAPPKRPAVASARPSILPSKD-----VKPKPIADAKAPEK 519
Query: 292 GQGPNTKAAAPAKGSGSK---VVPAHLSRKTEAPKGPRKAG----LPIKASSSKVSSQRA 344
P+ A+APA SGSK V + A GP LP K ++ K + A
Sbjct: 520 RASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKTEGKPA 579
Query: 345 E 345
E
Sbjct: 580 E 580
>gi|104526627 triadin [Homo sapiens]
Length = 729
Score = 50.1 bits (118), Expect = 3e-06
Identities = 64/246 (26%), Positives = 99/246 (40%), Gaps = 32/246 (13%)
Query: 131 HKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKP 190
HK+KI+ +K P T + K K +K E + GK +K + AKV++ P
Sbjct: 186 HKEKIE-KKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTP 244
Query: 191 GAATEKARKQGGAA-----KDTRA--------------QSGEARKVPP--KPDKAMRAPS 229
EK K+ A KD A + G++ +PP ++A R
Sbjct: 245 SKPKEKEDKEKAAVSKHEQKDQYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTP 304
Query: 230 SAGGLSRKAKAKGSRSSQGDAEAYRKTKAE--SKSSKPTA---SKVKNGAASPTKK---K 281
++ L K K + +E +K K + KS K TA K + G AS TK+ K
Sbjct: 305 ASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVK 364
Query: 282 VVAKAKAPKAGQGPNT-KAAAPAKGSGSKVVPAHLSRK-TEAPKGPRKAGLPIKASSSKV 339
+ A+A A K + ++ K PA+ K K E K P+K K
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKA 424
Query: 340 SSQRAE 345
++RA+
Sbjct: 425 KTERAK 430
Score = 42.4 bits (98), Expect = 6e-04
Identities = 51/227 (22%), Positives = 85/227 (37%), Gaps = 19/227 (8%)
Query: 137 PRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGK----VKKAAKRPAKVQKPPPKPGA 192
P + A P + +G KK +E K K +KK +++ + +PG
Sbjct: 295 PTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPGK 354
Query: 193 ATE------KARKQGGAAKDTRAQSGEARKVPPKPD--KAMRAPSSAGGLSRKAKAKGSR 244
A+E K Q A KD + + + K P + + K + + K
Sbjct: 355 ASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEH 414
Query: 245 SSQGDAEAYRKTKAESKSSKPTASK--VKNGAASPTKKKVVAKAKAPKAGQGPN-TKAAA 301
S D + KT+ + + K V T K V + + K+G+ + K
Sbjct: 415 SVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKE 474
Query: 302 PAKGSGSKVVPAHLSRK---TEAPKGPRKAGLPIKASSSKVSSQRAE 345
P KG K VPA L K T+ + KAG +K ++ ++ E
Sbjct: 475 PIKGKEEK-VPASLKEKEPETKKDEKMSKAGKEVKPKPPQLQGKKEE 520
Score = 37.7 bits (86), Expect = 0.015
Identities = 40/175 (22%), Positives = 63/175 (36%), Gaps = 19/175 (10%)
Query: 156 GPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEAR 215
G KP ++ PP + + +P P A EK +G K + + E +
Sbjct: 280 GDLKPGQSPAIPPPLPT--------EQASRPTPASPALEEK---EGEKKKAEKKVTSETK 328
Query: 216 KVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGD--------AEAYRKTKAESKSSKPTA 267
K + K +A + +K K S + QG A+ K + K+ KP
Sbjct: 329 KKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKKEDSKKTKKPAE 388
Query: 268 SKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAP 322
+ G K+K V AK+PK + AK +K +S K P
Sbjct: 389 VEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVP 443
Score = 37.7 bits (86), Expect = 0.015
Identities = 52/237 (21%), Positives = 85/237 (35%), Gaps = 28/237 (11%)
Query: 120 GATGSFKLVPKHKKKIQPRKMAPATAPRRAGEA----------KGKGPKKPSEAKEDPPN 169
GA K VP K++ + + ++G+ KGK K P+ KE P
Sbjct: 434 GAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE 493
Query: 170 VGKVKKAAKRPAKVQ-KPPPKPGAATEK----ARKQGGAAKDTRAQSGEARKVPP----- 219
K +K +K +V+ KPP G EK +K+ A + Q + V P
Sbjct: 494 TKKDEKMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVS 553
Query: 220 --KPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKP------TASKVK 271
KP++ + A + + AK K ++ ++ K + P T S K
Sbjct: 554 HGKPEEKVLKQVKAVTIEKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKK 613
Query: 272 NGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKGPRKA 328
S + K A K + + K + PA +S+ E +KA
Sbjct: 614 KTEISEKESKEKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVEDVPASKKA 670
Score = 33.5 bits (75), Expect = 0.29
Identities = 32/136 (23%), Positives = 51/136 (37%), Gaps = 11/136 (8%)
Query: 151 EAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQ 210
E G + + + D P + K + + K +KP K K+ G K +
Sbjct: 119 EEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKE 178
Query: 211 SGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSS-----KP 265
E + + + P + + KAK + S+ KTK E K K
Sbjct: 179 KPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSE------EKTKKEVKGGKQEKVKQ 232
Query: 266 TASKVKNGAASPTKKK 281
TA+KVK +P+K K
Sbjct: 233 TAAKVKEVQKTPSKPK 248
>gi|237757312 synaptojanin 1 isoform c [Homo sapiens]
Length = 1295
Score = 49.7 bits (117), Expect = 4e-06
Identities = 71/275 (25%), Positives = 98/275 (35%), Gaps = 35/275 (12%)
Query: 96 LLKQALATGMRRGLLARPLNSK----------ARGATGSFKLVPKHKKKIQPRKMAPATA 145
LL Q L GL P +S + G S + P P + ++
Sbjct: 1025 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSS 1084
Query: 146 PRRAGEAKG---KGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGA-ATEKARKQG 201
P A A K P +P E K PP + RPA Q+PPP GA + RK+
Sbjct: 1085 PIDAQPATPLPQKDPAQPLEPKRPPP--PRPVAPPTRPAPPQRPPPPSGARSPAPTRKEF 1142
Query: 202 GAAKDT-RAQSGEARKVPPKPDKAMRAPSSAGGLSRK-----------AKAKGSRSSQG- 248
GA K + + P P + P AG + + A +R+S G
Sbjct: 1143 GAPKSPGTTRKDNIGRSQPSPQAGLAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGR 1202
Query: 249 -DAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSG 307
E+ KT SK S +K AA P + + A+ Q P AAP SG
Sbjct: 1203 LTPESQSKTSETSKGSTFLPEPLKPQAAFPPQSSLPPPAQRL---QEPLVPVAAPMPQSG 1259
Query: 308 SKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQ 342
+ P + P+ LP +ASS Q
Sbjct: 1260 PQ--PNLETPPQPPPRSRSSHSLPSEASSQPQQEQ 1292
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 49.7 bits (117), Expect = 4e-06
Identities = 43/210 (20%), Positives = 74/210 (35%), Gaps = 18/210 (8%)
Query: 142 PATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVK-KAAKRPAKVQKPPPKPGAATEKARKQ 200
P P G+ +G P+ ++++ PP GK + + + + Q PPP PG +
Sbjct: 47 PQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQG 106
Query: 201 GGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAES 260
G ++ T G+ + PP+ P G + +G SQG
Sbjct: 107 GNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQG---------PPP 157
Query: 261 KSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQG--------PNTKAAAPAKGSGSKVVP 312
KP + G S + + K + P +G P P G +
Sbjct: 158 HPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQ 217
Query: 313 AHLSRKTEAPKGPRKAGLPIKASSSKVSSQ 342
A + K + P P + G P + + + Q
Sbjct: 218 APPAGKPQGPPPPPQGGRPPRPAQGQQPPQ 247
Score = 45.4 bits (106), Expect = 7e-05
Identities = 43/202 (21%), Positives = 71/202 (35%), Gaps = 17/202 (8%)
Query: 149 AGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTR 208
+G+ +G+ P+ ++ + PP GK + + + PP P E QGG
Sbjct: 33 SGKPEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGG------ 86
Query: 209 AQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSS----QGDAEAYRKTKAESKSSK 264
+++ PP P K R P G S+ + QG +++R K +
Sbjct: 87 ---NQSQGPPPHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPER 143
Query: 265 PTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSKVVPAHLSRKTEAPKG 324
P + N + P + P+ G + + P K G P K + P
Sbjct: 144 P-PPQGGNQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGP---PQQEGNKPQGPPP 199
Query: 325 PRKAGLPIKASSSKVSSQRAEA 346
P K P A + Q A
Sbjct: 200 PGKPQGPPPAGGNPQQPQAPPA 221
Score = 40.0 bits (92), Expect = 0.003
Identities = 39/173 (22%), Positives = 57/173 (32%), Gaps = 28/173 (16%)
Query: 137 PRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEK 196
P P P + G P P + + PP G + +PPP PG E+
Sbjct: 94 PHPGKPERPPPQGGNQSQGTPPPPGKPERPPPQGGN---------QSHRPPPPPG-KPER 143
Query: 197 ARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKT 256
QGG +++ PP P K P G SR A++ + + K
Sbjct: 144 PPPQGG---------NQSQGPPPHPGKPEGPPPQEGNKSRSARSPPGKPQGPPQQEGNKP 194
Query: 257 KAESKSSKPTASKVKNG----AASPTKKKVVAKAKAPKAGQGPNTKAAAPAKG 305
+ KP G +P K P+ G+ P PA+G
Sbjct: 195 QGPPPPGKPQGPPPAGGNPQQPQAPPAGKPQGPPPPPQGGRPPR-----PAQG 242
>gi|30795231 brain abundant, membrane attached signal protein 1
[Homo sapiens]
Length = 227
Score = 49.3 bits (116), Expect = 5e-06
Identities = 51/217 (23%), Positives = 85/217 (39%), Gaps = 28/217 (12%)
Query: 130 KHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPK 189
K KK + + A + +A+G ++ KE P +AA PA+ ++ K
Sbjct: 4 KLSKKKKGYNVNDEKAKEKDKKAEGAATEEEGTPKESEP------QAAAEPAEAKEGKEK 57
Query: 190 PGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGD 249
P E ++ KD A EA K P+ + + +AKA+ ++ +
Sbjct: 58 PDQDAEGKAEEKEGEKDAAAAKEEAPKAEPEKTEG----------AAEAKAEPPKAPE-- 105
Query: 250 AEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAKGSGSK 309
++ A ++ A K AA+P A++ AP AG+ P+ + P K
Sbjct: 106 ----QEQAAPGPAAGGEAPKAAEAAAAP------AESAAPAAGEEPSKEEGEPKKTEAPA 155
Query: 310 VVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA 346
A ++ AP K G A SSK + EA
Sbjct: 156 APAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEA 192
Score = 47.0 bits (110), Expect = 3e-05
Identities = 54/211 (25%), Positives = 85/211 (40%), Gaps = 40/211 (18%)
Query: 111 ARPLNSKARGATGSFKLVPKHKK-------------KIQPRKMAPATAPRRAGE-----A 152
A+ + KA GA + PK + K +P + A A + GE A
Sbjct: 19 AKEKDKKAEGAATEEEGTPKESEPQAAAEPAEAKEGKEKPDQDAEGKAEEKEGEKDAAAA 78
Query: 153 KGKGPKKP-------SEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGGAA- 204
K + PK +EAK +PP + ++AA PA + P AA A AA
Sbjct: 79 KEEAPKAEPEKTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAG 138
Query: 205 KDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAESKSSK 264
++ + GE PK +A AP++ S A A S+ +A + SSK
Sbjct: 139 EEPSKEEGE-----PKKTEAPAAPAAQETKSDGAPASDSKPGSSEA---------APSSK 184
Query: 265 PTASKVKNGAASPTKKKVVAKAKAPKAGQGP 295
T + + +++P + A A+ PK + P
Sbjct: 185 ETPAATEAPSSTPKAQGPAASAEEPKPVEAP 215
Score = 35.0 bits (79), Expect = 0.099
Identities = 40/154 (25%), Positives = 59/154 (38%), Gaps = 20/154 (12%)
Query: 117 KARGATGSFKLVPKHKKKIQ--PRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVK 174
K GA + PK ++ Q P A AP+ A A A E+P
Sbjct: 89 KTEGAAEAKAEPPKAPEQEQAAPGPAAGGEAPKAAEAAAAPAESAAPAAGEEP------S 142
Query: 175 KAAKRPAKVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGL 234
K P K + P A ++ + G A D++ S EA + A APSS
Sbjct: 143 KEEGEPKKTEAP---AAPAAQETKSDGAPASDSKPGSSEAAPSSKETPAATEAPSST--- 196
Query: 235 SRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTAS 268
KA+G +S AE + +A + +S T +
Sbjct: 197 ---PKAQGPAAS---AEEPKPVEAPAANSDQTVT 224
>gi|237757326 synaptojanin 1 isoform d [Homo sapiens]
Length = 1526
Score = 49.3 bits (116), Expect = 5e-06
Identities = 61/245 (24%), Positives = 95/245 (38%), Gaps = 26/245 (10%)
Query: 96 LLKQALATGMRRGLLARPLNSK----------ARGATGSFKLVPKHKKKIQPRKMAPATA 145
LL Q L GL P +S + G S + P P + ++
Sbjct: 1020 LLPQHLQPSSSSGLGTSPSSSPRTSPCQSPTISEGPVPSLPIRPSRAPSRTPGPPSAQSS 1079
Query: 146 PRRAGEAKG---KGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKARKQGG 202
P A A K P +P E K PP + RPA Q+PPP G + + Q G
Sbjct: 1080 PIDAQPATPLPQKDPAQPLEPKRPPPP--RPVAPPTRPAPPQRPPPPSGRS--QPSPQAG 1135
Query: 203 AAKDTRAQSGEARKVPPKPDKAMRAP-----SSAGGLSRKAKAKGSRSSQGDAEAYRKTK 257
A A AR P + AP +SAG L+ ++++K S +S+G +
Sbjct: 1136 LAGPGPAGYSTARPTIPPRAGVISAPQSHARASAGRLTPESQSKTSETSKG--STFLPEP 1193
Query: 258 AESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPN--TKAAAPAKGSGSKVVPAHL 315
+ +++ P S + A + V A P++G PN T P + S +P+
Sbjct: 1194 LKPQAAFPPQSSLPPPAQRLQEPLVPVAAPMPQSGPQPNLETPPQPPPRSRSSHSLPSEA 1253
Query: 316 SRKTE 320
S + +
Sbjct: 1254 SSQPQ 1258
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 48.5 bits (114), Expect = 9e-06
Identities = 52/226 (23%), Positives = 84/226 (37%), Gaps = 21/226 (9%)
Query: 142 PATAPR----RAGEAKG-KGPKKPSEAKE-----DPPNVGKVKKAAKRPAKVQKPPPKPG 191
PAT P+ RA E G KGP++P E E D V K + A + + P G
Sbjct: 2431 PATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAG 2490
Query: 192 AATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAE 251
E + A S E + PK A GL+ + + AE
Sbjct: 2491 GWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAE 2550
Query: 252 AYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQG-----------PNTKAA 300
++ES SS + S + ++S + + + + K G G +++AA
Sbjct: 2551 QDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAA 2610
Query: 301 APAKGSGSKVVPAHLSRKTEAPKGPRKAGLPIKASSSKVSSQRAEA 346
+PA S S + S + + + +SSS SS + +
Sbjct: 2611 SPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2656
Score = 38.1 bits (87), Expect = 0.012
Identities = 31/130 (23%), Positives = 54/130 (41%), Gaps = 7/130 (5%)
Query: 201 GGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKTKAES 260
G ++ A S A + + SS+ S + + S SS + + + + S
Sbjct: 2596 GTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2655
Query: 261 KSSKPTASKVKNGAASPTKKKVVAKAK---APKAGQGPNTKAAAPAKG---SGSKVVPAH 314
SS ++S + ++S T + + AP GP+ +AA P K +G AH
Sbjct: 2656 SSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAH 2715
Query: 315 L-SRKTEAPK 323
+KT AP+
Sbjct: 2716 SPGKKTPAPQ 2725
Score = 35.8 bits (81), Expect = 0.058
Identities = 42/158 (26%), Positives = 67/158 (42%), Gaps = 28/158 (17%)
Query: 191 GAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAG-----GLSRKAKAKGSRS 245
GA + + + G AK+ + GE + K D R ++G L+++A+A+G R
Sbjct: 193 GAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQEARAEG-RQ 251
Query: 246 SQGD---AEAYRKTKAESKSS----KPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTK 298
+G AE AESK+ +P+ + NG A V A +AG+G +
Sbjct: 252 DRGPPRLAERLSPFLAESKTKNAALQPSVLTMCNGGAG----DVGLPALVAEAGRGGAKE 307
Query: 299 AAAPAKGS-----------GSKVVPAHLSRKTEAPKGP 325
AA +G+ G + P+ L PKGP
Sbjct: 308 AARQDEGARLLRRTETLLPGPRPCPSPLPPPPAPPKGP 345
Score = 33.9 bits (76), Expect = 0.22
Identities = 31/123 (25%), Positives = 49/123 (39%), Gaps = 9/123 (7%)
Query: 182 KVQKPPPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAK 241
K+Q P P A+++ ++ T +GE + + A + G AKAK
Sbjct: 2285 KIQCAEPSPALLVPSAKRR---SRKTSKDTGEGKDGGTAGSEEPGAKARGRGRKPSAKAK 2341
Query: 242 GSRSSQGDAEAYRKTKAESKSSKPTASKVKN--GAASPTKKKVVAKAKAPKAGQGPNTKA 299
G R+ A + S P A + + G+ + V +AKAPKA P +
Sbjct: 2342 GDRA----ATLEEGNPTDEVPSTPLALEPSSTPGSKKSPPEPVDKRAKAPKARPAPPQPS 2397
Query: 300 AAP 302
AP
Sbjct: 2398 PAP 2400
Score = 31.6 bits (70), Expect = 1.1
Identities = 32/149 (21%), Positives = 55/149 (36%), Gaps = 6/149 (4%)
Query: 137 PRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEK 196
P APAT R + P+K + +D + K KK + PPP+ A +
Sbjct: 2014 PVSTAPATKTSRCAKGGPLSPRKDAGRAKDRKDPRKKKKGKEAGPGAGLPPPRAPALPSE 2073
Query: 197 ARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAEAYRKT 256
AR A+ T A+ +A+ + K R A +K S +++ D E + +
Sbjct: 2074 ARAP-HASSLTAAKRSKAKAKGKEVKKENRGKGGA-----VSKLMESMAAEEDFEPNQDS 2127
Query: 257 KAESKSSKPTASKVKNGAASPTKKKVVAK 285
P V+ + ++ K
Sbjct: 2128 SFSEDEHLPRGGAVERPLTPAPRSCIIDK 2156
Score = 30.0 bits (66), Expect = 3.2
Identities = 30/160 (18%), Positives = 51/160 (31%), Gaps = 8/160 (5%)
Query: 192 AATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSSQGDAE 251
AA+ + ++ + + S + + + SS+ S + + S SS +
Sbjct: 2609 AASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2668
Query: 252 AYRKTKAESKSSK-------PTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAK 304
+ T +S S PTA A K KA+ G T A P
Sbjct: 2669 SSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQPQA 2728
Query: 305 GSGSKVVPAHLSRKTEAPKGPRK-AGLPIKASSSKVSSQR 343
P + A P+K G+ + + QR
Sbjct: 2729 PPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQR 2768
Score = 29.6 bits (65), Expect = 4.1
Identities = 29/118 (24%), Positives = 39/118 (33%), Gaps = 25/118 (21%)
Query: 187 PPKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAGGLSRKAKAKGSRSS 246
P A KA KQ G A+ + G K P P P L KA+A
Sbjct: 2693 PSAQAALPTKATKQAGKARPSAHSPG---KKTPAPQPQAPPPQPTQPLQPKAQA------ 2743
Query: 247 QGDAEAYRKTKAESKSSKPTASKVKNGAASPTKKKVVAKAKAPKAGQGPNTKAAAPAK 304
S+P K + G PT K++ + + P P A PA+
Sbjct: 2744 -------------GAKSRP---KKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPAR 2785
Score = 29.3 bits (64), Expect = 5.4
Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 2/67 (2%)
Query: 141 APATAPRRAGEAKGKGP--KKPSEAKEDPPNVGKVKKAAKRPAKVQKPPPKPGAATEKAR 198
A A P G A G G K+ E E G+ A+ A+V+ PP A + +
Sbjct: 633 AQARLPHSGGPAAGGGRQLKRDPERPESAKAFGREGSGAQGEAEVRHPPVGIAVAVARQK 692
Query: 199 KQGGAAK 205
GG+ +
Sbjct: 693 DSGGSGR 699
Score = 28.5 bits (62), Expect = 9.2
Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 3/89 (3%)
Query: 132 KKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKR---PAKVQKPPP 188
KK P+ AP P + + K + K K + ++ K+ AKR P+ +P
Sbjct: 2719 KKTPAPQPQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKI 2778
Query: 189 KPGAATEKARKQGGAAKDTRAQSGEARKV 217
+ K G R G+ARK+
Sbjct: 2779 AAFLPARQLWKWFGKPTQRRGMKGKARKL 2807
>gi|20544168 histone cluster 1, H1t [Homo sapiens]
Length = 207
Score = 48.5 bits (114), Expect = 9e-06
Identities = 54/217 (24%), Positives = 91/217 (41%), Gaps = 28/217 (12%)
Query: 8 SDISPSSTSTAGSSRSPESEKPGPSHGGVPPGGPSHSSLPVGRRHPPVLRMVLEALQAGE 67
S+ P+++++AG + EK G P G +S V V +++ EAL +
Sbjct: 2 SETVPAASASAGVAAM---EKLPTKKRGRKPAGLISASRKVPNLS--VSKLITEALSVSQ 56
Query: 68 QRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARPLNSKARGATGSFKL 127
+R G S+ A+K + DV + +K +L + + +G+L + ++ GA+GSFKL
Sbjct: 57 ERVGMSLVALKKALAAA--GYDVEKNNSRIKLSLKSLVNKGILVQ---TRGTGASGSFKL 111
Query: 128 VPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKVKKAAKRPAKVQKPP 187
KK+ P+ +T + K K P K K AK
Sbjct: 112 ----SKKVIPK----STRSKAKKSVSAKTKKLVLSRDSKSPKTAKTNKRAK--------- 154
Query: 188 PKPGAATEKARKQGGAAKDTRAQSGEARKVPPKPDKA 224
KP A T K + G AK + + + V + K+
Sbjct: 155 -KPRATTPKTVRSGRKAKGAKGKQQQKSPVKARASKS 190
>gi|145309324 FH2 domain containing 1 [Homo sapiens]
Length = 1143
Score = 48.1 bits (113), Expect = 1e-05
Identities = 77/337 (22%), Positives = 124/337 (36%), Gaps = 37/337 (10%)
Query: 4 GSVTSDISPSSTSTAGSS--RSPESEKPGP--------SHGGVPPGGPSHSSLPVGRRHP 53
GS++S + S S+ SP E P P GG+P P+ V +
Sbjct: 806 GSMSSGVGEMGDSQVSSNPTSSPPGEAPAPVSVDSEPSCKGGLPRDKPTKRKDVVAPKRG 865
Query: 54 PVLRMVLEALQAGEQRRGTSVAAIKLYILHKYPTVDVLRFKYLLKQALATGMRRGLLARP 113
+ A + G RR A + L + + + K + G RR L+
Sbjct: 866 SLKEASPGASKPGSARRSQGAVAKSVRTLTASENESMRKVMPITKSSRGAGWRRPELSS- 924
Query: 114 LNSKARGATGSFKLVPKHKKKIQPRKMAPATAPRRAGEAKGKGPKKPSEAKEDPPNVGKV 173
++ S V + ++ R A R + G +P P G
Sbjct: 925 -RGPSQNPPSSTDTVWSRQNSVR-RASTGAEEQRLPRGSSGSSSTRPGRDVPLQPR-GSF 981
Query: 174 KKAAKRPAKVQKPPPKPGA-ATEKARKQGGAAKDTRAQSGEARKVPPKPDKAMRAPSSAG 232
KK + +P + P KP T +A +G ++ + + VP P + R PS A
Sbjct: 982 KKPSAKPLR-NLPRQKPEENKTCRAHSEG---PESPKEEPKTPSVPSVPHELPRVPSFA- 1036
Query: 233 GLSRKAKAKGSRSSQGDAEAYRKTKAESKSSKPTASKVKNGA--ASPTKKKVVAKA---- 286
R A SRS + D K +++ +VK A+P + +A
Sbjct: 1037 ---RNTVASSSRSMRTDLPPVAKAPGITRTVSQRQLRVKGDPEDAAPKDSSTLRRASSAR 1093
Query: 287 ---KAPKAGQGP--NTKAAAPAKGSGSKVVPAHLSRK 318
K P++ +GP NT+A A+G+G + A L RK
Sbjct: 1094 APKKRPESAEGPSANTEAPLKARGAGER---ASLRRK 1127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.122 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,057,187
Number of Sequences: 37866
Number of extensions: 918053
Number of successful extensions: 8522
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 900
Number of HSP's that attempted gapping in prelim test: 5858
Number of HSP's gapped (non-prelim): 2769
length of query: 346
length of database: 18,247,518
effective HSP length: 103
effective length of query: 243
effective length of database: 14,347,320
effective search space: 3486398760
effective search space used: 3486398760
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.