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Search of human proteins with 24432032
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24432032 zinc finger protein 503 [Homo sapiens]
(646 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24432032 zinc finger protein 503 [Homo sapiens] 1330 0.0
gi|13376611 zinc finger protein 703 [Homo sapiens] 598 e-171
gi|109255251 loricrin [Homo sapiens] 85 2e-16
gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens] 79 2e-14
gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2 ... 76 1e-13
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 76 1e-13
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 76 1e-13
gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens] 72 1e-12
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 69 2e-11
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 64 3e-10
gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens] 62 2e-09
gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens] 62 2e-09
gi|7710121 engrailed homeobox 2 [Homo sapiens] 62 2e-09
gi|51479192 ring finger protein 1 [Homo sapiens] 60 5e-09
gi|126352446 elastin isoform d precursor [Homo sapiens] 60 6e-09
gi|126352322 elastin isoform c precursor [Homo sapiens] 60 6e-09
gi|55956899 keratin 9 [Homo sapiens] 60 6e-09
gi|195972866 keratin 10 [Homo sapiens] 60 6e-09
gi|126352608 elastin isoform e precursor [Homo sapiens] 59 1e-08
gi|126352440 elastin isoform a precursor [Homo sapiens] 59 1e-08
gi|154146231 DMRT-like family A2 [Homo sapiens] 59 1e-08
gi|48762934 alpha 2 type I collagen [Homo sapiens] 59 1e-08
gi|47132620 keratin 2 [Homo sapiens] 59 1e-08
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 58 2e-08
gi|55956910 meningioma 1 [Homo sapiens] 58 2e-08
gi|45439359 triple functional domain (PTPRF interacting) [Homo s... 58 2e-08
gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens] 58 3e-08
gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens] 57 4e-08
gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens] 57 7e-08
gi|119395750 keratin 1 [Homo sapiens] 56 9e-08
>gi|24432032 zinc finger protein 503 [Homo sapiens]
Length = 646
Score = 1330 bits (3441), Expect = 0.0
Identities = 646/646 (100%), Positives = 646/646 (100%)
Query: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV
Sbjct: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
Query: 61 PPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC 120
PPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC
Sbjct: 61 PPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC 120
Query: 121 SQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSK 180
SQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSK
Sbjct: 121 SQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSK 180
Query: 181 PGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGG 240
PGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGG
Sbjct: 181 PGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGG 240
Query: 241 MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDG 300
MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDG
Sbjct: 241 MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDG 300
Query: 301 GPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP 360
GPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP
Sbjct: 301 GPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYP 360
Query: 361 GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS 420
GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS
Sbjct: 361 GSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPS 420
Query: 421 VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHS 480
VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHS
Sbjct: 421 VMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHS 480
Query: 481 SLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLR 540
SLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLR
Sbjct: 481 SLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDKRFATSEELLSHLR 540
Query: 541 THTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSS 600
THTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSS
Sbjct: 541 THTAFPGTDKLLSGYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLALRSPHHALGLSS 600
Query: 601 RYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ 646
RYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ
Sbjct: 601 RYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRLTTASALGYQ 646
>gi|13376611 zinc finger protein 703 [Homo sapiens]
Length = 590
Score = 598 bits (1542), Expect = e-171
Identities = 360/666 (54%), Positives = 412/666 (61%), Gaps = 96/666 (14%)
Query: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
MS +P+ S R+ + SG G GGGG A PA S L
Sbjct: 1 MSDSPAGSNPRTPESSGSGSGGGGKRPAVPAAVSLL------------------------ 36
Query: 61 PPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC 120
PP+DPLRQANRLPI+VLKML+A TGH+LHPEYLQPL STPVSPIELDAKKSPLALLAQTC
Sbjct: 37 PPADPLRQANRLPIRVLKMLSAHTGHLLHPEYLQPLSSTPVSPIELDAKKSPLALLAQTC 96
Query: 121 SQIGKPDPSPSSKLSSVASNGGGAGG---AGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP 177
SQIGKPDP PSSKL+SVA+ G G G A G + +L D EDKSSFKP
Sbjct: 97 SQIGKPDPPPSSKLNSVAAAANGLGAEKDPGRSAPGAASAAAALKQLGDSPAEDKSSFKP 156
Query: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSS----------EKSGFRVPSATCQPFTPRTG 227
YSK G GGG G VSS +K+GFRVPSA C PF P
Sbjct: 157 YSK---------GSGGGDSRKDSGSSSVSSTSSSSSSSPGDKAGFRVPSAACPPFPPHGA 207
Query: 228 SPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCG 287
S+S+S+ SPGG S GG+P D K VGGG + P A +S G
Sbjct: 208 PVSASSSSSSPGG---SRGGSPHHSDCKNGGGVGGGELDKKDQEPKPSPEPAA---VSRG 261
Query: 288 GGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQ 347
GG G PG GG+ +SG P S+++G+G VAPVSPYKPG
Sbjct: 262 GG----------GEPGAH------GGAESGASGRKSEPP--SALVGAGHVAPVSPYKPGH 303
Query: 348 TVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGC--S 405
+VFPLPP+ + Y GS+ GAYAGYP QF+P LDP+K G LVG QL +G LG
Sbjct: 304 SVFPLPPSSIGYHGSIVGAYAGYPSQFVP---GLDPSKSG-LVGGQL----SGGLGLPPG 355
Query: 406 KPAGSSPLAGASPPSVMTASLCRDPYCL-SYHCASHLAGAAAASASCAHDPAAAAAALKS 464
KP SSPL GASPPS + LCRDPYCL YH ASHL G++ ++ S AHDPA +
Sbjct: 356 KPPSSSPLTGASPPSFL-QGLCRDPYCLGGYHGASHLGGSSCSTCS-AHDPAGPSLK-AG 412
Query: 465 GYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGP 524
GYPLVYP HPL S +AA AA L GHPLY YGFML N+PLPH CNWV+A+GP
Sbjct: 413 GYPLVYPGHPLQPAALSSSAAQAA------LPGHPLYTYGFMLQNEPLPHSCNWVAASGP 466
Query: 525 CDKRFATSEELLSHLRTHTAFPGTDKLLSGYPSSSSLASAAAAAMA---CHMHIPTSGAP 581
CDKRFATSEELLSHLRTHTA PG +KLL+ YP +S L SAAAAA A CH+H+P AP
Sbjct: 467 CDKRFATSEELLSHLRTHTALPGAEKLLAAYPGASGLGSAAAAAAAAASCHLHLPPPAAP 526
Query: 582 GSPGTLALRSPHHALGLSSRYHPYSKSPLPTPGA-PVPVPAATGPYYSPYALYGQRLTTA 640
GSPG+L+LR+P H LGL SRYHPY KS L T G VP GPYYSPYALYGQRL +A
Sbjct: 527 GSPGSLSLRNP-HTLGL-SRYHPYGKSHLSTAGGLAVPSLPTAGPYYSPYALYGQRLASA 584
Query: 641 SALGYQ 646
SALGYQ
Sbjct: 585 SALGYQ 590
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 84.7 bits (208), Expect = 2e-16
Identities = 76/236 (32%), Positives = 88/236 (37%), Gaps = 24/236 (10%)
Query: 125 KPDPSPSSKLSSVASNGGGAGGAGGGAAG--DKDTKSGPLKLSDIGVEDKSSFKPYSKPG 182
+P P P + GGG GG+GGG G G S G YS G
Sbjct: 7 QPTPQPPVDCVKTSGGGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGG---YSGGG 63
Query: 183 SDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGML 242
GGGGGGG GG GGG G S + SG S G +S G
Sbjct: 64 CGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSG---------GGSGCFSSGGGGSGCF 114
Query: 243 SSAGGAPEGKDDKKDTDVGGGGKGTGG---ASAEGGPTGLA-----HGRISCGGGINVDV 294
SS GG G + GGG G G +S GG +G A +G +S GG
Sbjct: 115 SSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGS 174
Query: 295 NQHPDGGPGGKALGSDCGGS--SGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQT 348
GG GG G GGS G SSG S SS + AP Y G +
Sbjct: 175 GCFSSGGGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSS 230
Score = 73.9 bits (180), Expect = 4e-13
Identities = 65/214 (30%), Positives = 77/214 (35%), Gaps = 26/214 (12%)
Query: 135 SSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKK--EPGGGG 192
SS GGG GG GGG+ G +K S G +S G GGGG
Sbjct: 68 SSGGGGGGGIGGCGGGSGGS-------VKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGG 120
Query: 193 -----------GGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGM 241
GGGG GGG G SS GF + CQ + G SS S+ G
Sbjct: 121 SSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSY----GGVSSGGSSGGGSGC 176
Query: 242 LSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGG 301
SS GG G G G G+ G S G + + SC + GG
Sbjct: 177 FSSGGGG--GSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGG 234
Query: 302 PGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSG 335
GG S GG S G G S S ++ G
Sbjct: 235 SGGSGCFSSGGGGGSSGCGGGSSGIGSGCIISGG 268
Score = 69.7 bits (169), Expect = 8e-12
Identities = 65/192 (33%), Positives = 72/192 (37%), Gaps = 28/192 (14%)
Query: 176 KPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASA 235
+P +P D + GGGGGGGG GGGG C F SS S
Sbjct: 7 QPTPQPPVDCVKTSGGGGGGGGSGGGG----------------CGFFGGGGSGGGSSGSG 50
Query: 236 CS-PGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASA-EGGPTGLAHGRISCGGGINVD 293
C GG S GG G GGGG G GG GG + G S GGG
Sbjct: 51 CGYSGGGGYSGGGCGGGSSG------GGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGC- 103
Query: 294 VNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLP 353
GG G S GGSSG SG S SS GSG + GQ V
Sbjct: 104 ---FSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQS 160
Query: 354 PAGMTYPGSLAG 365
G++ GS G
Sbjct: 161 YGGVSSGGSSGG 172
Score = 63.2 bits (152), Expect = 7e-10
Identities = 64/206 (31%), Positives = 73/206 (35%), Gaps = 48/206 (23%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKS----SFKPYSKPGSDKKEPG----G 190
S+GGG+G G G SG G ++ S+ S GS G G
Sbjct: 121 SSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSG 180
Query: 191 GGGG------GGGGGGGGGGVSSEKSGF----RVPSATCQPFTPRTGSPSSSASACSPGG 240
GGGG GGG G GGG SG+ +V +C P P G SS G
Sbjct: 181 GGGGSVCGYSGGGSGCGGGSSGGSGSGYVSSQQVTQTSCAP-QPSYGGGSSGGGGSGGSG 239
Query: 241 MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDG 300
SS GG + GGG G G G G CGGG
Sbjct: 240 CFSSGGGGGS-------SGCGGGSSGIGSGCIISG------GGSVCGGG---------SS 277
Query: 301 GPGGKALGSDCGGSSGSSSGSGPSAP 326
G GG GGSS SGSG P
Sbjct: 278 GGGG-------GGSSVGGSGSGKGVP 296
Score = 39.3 bits (90), Expect = 0.011
Identities = 19/36 (52%), Positives = 21/36 (58%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
GGG GGGG G ++S G SSG G GSS GS
Sbjct: 226 GGGSSGGGGSGGSGCFSSGGGGGSSGCGGGSSGIGS 261
Score = 38.1 bits (87), Expect = 0.025
Identities = 61/213 (28%), Positives = 68/213 (31%), Gaps = 90/213 (42%)
Query: 12 SSKHSGGGGGG----GGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLR 67
SS S GGG G GGGGG+ SG SG G GSS GS +V S +
Sbjct: 165 SSGGSSGGGSGCFSSGGGGGS----VCGYSGGGSGCGGGSS-GGSGSGYV----SSQQVT 215
Query: 68 QANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPD 127
Q + P QP S G
Sbjct: 216 QTSCAP--------------------QP-------------------------SYGGGSS 230
Query: 128 PSPSSKLSSVASNGGGAG--GAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDK 185
S S S+GGG G G GGG++G GS
Sbjct: 231 GGGGSGGSGCFSSGGGGGSSGCGGGSSG---------------------------IGSGC 263
Query: 186 KEPGGG---GGGGGGGGGGGGGVSSEKSGFRVP 215
GGG GGG GGGGGG V SG VP
Sbjct: 264 IISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVP 296
Score = 38.1 bits (87), Expect = 0.025
Identities = 35/107 (32%), Positives = 42/107 (39%), Gaps = 16/107 (14%)
Query: 122 QIGKPDPSPSSKLSSVASNGGGAGGAG----GGAAGDKDTKSGPLKLSDIGVEDKSSFKP 177
Q+ + +P +S GGG+GG+G GG G G S IG S
Sbjct: 213 QVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCGGGS---SGIG-----SGCI 264
Query: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTP 224
S GS GGG GGGGGG G S G + T Q P
Sbjct: 265 ISGGGS----VCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQKQAP 307
Score = 36.2 bits (82), Expect = 0.096
Identities = 20/47 (42%), Positives = 24/47 (51%), Gaps = 1/47 (2%)
Query: 5 PSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
P + +++S GGGGGG GGGG G SSG G G S G
Sbjct: 12 PPVDCVKTSG-GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGG 57
Score = 34.3 bits (77), Expect = 0.37
Identities = 20/46 (43%), Positives = 23/46 (50%), Gaps = 6/46 (13%)
Query: 12 SSKHSGGGGGGGGG------GGADPAWTSALSGNSSGPGPGSSPAG 51
S K+SGGGG GGG GG S+ G SSG G G +G
Sbjct: 87 SVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSG 132
Score = 32.7 bits (73), Expect = 1.1
Identities = 18/40 (45%), Positives = 22/40 (55%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
SS GGGG GG GGG+ + + G SSG G G +G
Sbjct: 68 SSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSG 107
Score = 31.2 bits (69), Expect = 3.1
Identities = 18/43 (41%), Positives = 19/43 (44%), Gaps = 5/43 (11%)
Query: 15 HSGGGGGGGGGGGADPAWTSALSGNSSGP-----GPGSSPAGS 52
+SGGG GGG GG G S G G GSS GS
Sbjct: 59 YSGGGCGGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGS 101
Score = 30.8 bits (68), Expect = 4.1
Identities = 17/36 (47%), Positives = 19/36 (52%), Gaps = 4/36 (11%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
SGGGG GGG G S+ G SSG G G +G
Sbjct: 116 SGGGGSSGGGSGC----FSSGGGGSSGGGSGCFSSG 147
Score = 30.4 bits (67), Expect = 5.3
Identities = 14/35 (40%), Positives = 18/35 (51%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
GGGG GGG G+ ++ + G G GSS G
Sbjct: 38 GGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGG 72
Score = 30.0 bits (66), Expect = 6.9
Identities = 22/54 (40%), Positives = 24/54 (44%), Gaps = 8/54 (14%)
Query: 2 STAPSLSALRSSKHSGGGGGGG----GGGGADPAWTSALSGNSSGPGPGSSPAG 51
S AP S S GG GG G GGGG +S G SSG G G +G
Sbjct: 218 SCAPQPSYGGGSSGGGGSGGSGCFSSGGGGG----SSGCGGGSSGIGSGCIISG 267
Score = 29.6 bits (65), Expect = 9.0
Identities = 15/40 (37%), Positives = 17/40 (42%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPF 56
GGG GGGGGG G+ G G S G + F
Sbjct: 65 GGGSSGGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCF 104
>gi|39812496 Sp8 transcription factor isoform 1 [Homo sapiens]
Length = 508
Score = 78.6 bits (192), Expect = 2e-14
Identities = 126/500 (25%), Positives = 159/500 (31%), Gaps = 152/500 (30%)
Query: 111 SPLALLAQTCSQIGKPDPSPSS------------------------------------KL 134
+PLA+LA TC++IG P PSPSS +
Sbjct: 15 TPLAMLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGV 74
Query: 135 SSVASNGGGAGGAGGGAA---------GDKDTKSGPLKLSDIGVEDKS------------ 173
S + NGG + A AA D + G S + S
Sbjct: 75 SGASRNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAA 134
Query: 174 SFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSS-EKSGFRVPSATCQPFT--------- 223
S P++ S + PG GG GGGGGGGGGG S+ + G P + T
Sbjct: 135 SSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIY 194
Query: 224 PRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGR 283
PR G S P A G DVG G ++ G H
Sbjct: 195 PRVGMAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLH-- 252
Query: 284 ISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPY 343
GG+ ++ P GG SD G S S+ SG S+ S G L+ P
Sbjct: 253 -PAAGGLQTSLHS-PLGG-----YNSDYSGLSHSAFSSGASSHLLSPA-GQHLMDGFKPV 304
Query: 344 KPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLG 403
PG +YP S AG A + S G
Sbjct: 305 LPG-----------SYPDSAPSPLAG-------------------------AGGSMLSAG 328
Query: 404 CSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALK 463
S P G SP + A S + C P C A L PA A+ K
Sbjct: 329 PSAPLGGSPRSSARRYS--GRATCDCPNCQE---AERLG------------PAGASLRRK 371
Query: 464 SGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANG 523
LH H + L H + G P +CNW+
Sbjct: 372 G----------LHSCH--IPGCGKVYGKTSHLKAHLRWHTG------ERPFVCNWLF--- 410
Query: 524 PCDKRFATSEELLSHLRTHT 543
C KRF S+EL HLRTHT
Sbjct: 411 -CGKRFTRSDELQRHLRTHT 429
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/244 (22%), Positives = 85/244 (34%), Gaps = 36/244 (14%)
Query: 102 SPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAG----DKDT 157
S L + + A A + P + S + +GG GG GGG G +D
Sbjct: 114 SAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDG 173
Query: 158 KSGPLKLSDI--GVEDKSSFKP---YSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGF 212
P+ +S + V+ P + P +P G G G G G S +
Sbjct: 174 SHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGA----SSWW 229
Query: 213 RVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASA 272
V + P +++A PG + +AGG + +GG G S
Sbjct: 230 DVGAGWIDVQNP-------NSAAALPGSLHPAAGGL----QTSLHSPLGGYNSDYSGLSH 278
Query: 273 EGGPTGLAHGRISCGGGINVD------VNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAP 326
+G + +S G +D +PD P S G+ GS +GPSAP
Sbjct: 279 SAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAP------SPLAGAGGSMLSAGPSAP 332
Query: 327 TSSS 330
S
Sbjct: 333 LGGS 336
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/49 (38%), Positives = 22/49 (44%)
Query: 294 VNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSP 342
V H GG GG + GS GG GS + S SA S L+ P P
Sbjct: 453 VKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEP 501
Score = 32.0 bits (71), Expect = 1.8
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 185 KKEPGGGGGGGGGGGGGGGGVSSE 208
K GGGGGGG G G GG S+
Sbjct: 454 KTHSGGGGGGGSAGSGSGGKKGSD 477
Score = 30.4 bits (67), Expect = 5.3
Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 11/54 (20%)
Query: 15 HSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHA---VPPSDP 65
HSGGGGGGG G SG G S + + P H+ + P +P
Sbjct: 456 HSGGGGGGGSAGSG--------SGGKKGSDTDSEHSAAGSPPCHSPELLQPPEP 501
Score = 30.0 bits (66), Expect = 6.9
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 8/58 (13%)
Query: 16 SGGGGGGGGGGGA--------DPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDP 65
SGGGGGGGGGG + P + S + + G G P+ PS P
Sbjct: 155 SGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHP 212
Score = 29.6 bits (65), Expect = 9.0
Identities = 13/24 (54%), Positives = 15/24 (62%)
Query: 4 APSLSALRSSKHSGGGGGGGGGGG 27
A S ++ SGG GGGGGGGG
Sbjct: 140 ANDYSVFQAPGVSGGSGGGGGGGG 163
>gi|40068464 AT rich interactive domain 1B (SWI1-like) isoform 2
[Homo sapiens]
Length = 2191
Score = 75.9 bits (185), Expect = 1e-13
Identities = 114/425 (26%), Positives = 152/425 (35%), Gaps = 100/425 (23%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPP--SDPLRQANRLPI 74
GG GGG G D S G + P G PP S P + + P
Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG---------PPLLSKPGDEDDAPP- 132
Query: 75 KVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPS---PS 131
KM G HP L L T P+ + A + + + G P+ P
Sbjct: 133 ---KMGEPAGGRYEHPG-LGAL-GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG 187
Query: 132 SKLSSVASNGGG-----------AGGAGGGAAGDKDTKSGPLKLSDIGVEDK--SSFKPY 178
+ GG A A GA G D PL+ S G + + + Y
Sbjct: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD----PLQNSHEGYPNSQCNHYPGY 243
Query: 179 SKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSP 238
S+PG+ GGGGGGGG GGGGGGG + G + A A +
Sbjct: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAG------------------AGGAGAGAVAAAA 285
Query: 239 GGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHP 298
++AG GGGG G GG+SA G + GGG+ +
Sbjct: 286 AAAAAAAG--------------GGGGGGYGGSSAGYGVLSSPRQQ---GGGMMM------ 322
Query: 299 DGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMT 358
GPGG S ++GS++G G A + + G T P +T
Sbjct: 323 --GPGGGGAASLSKAAAGSAAG------------GFQRFAGQNQHPSGAT--PTLNQLLT 366
Query: 359 YPGSLAGAYAG-YPPQFLPHGVALDPTKPGSLVGAQLAAA----AAGSLGCSKPAGSSPL 413
P + +Y G YP P P++P S A AAA AA +G K G+
Sbjct: 367 SPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQ-Y 425
Query: 414 AGASP 418
A ASP
Sbjct: 426 AAASP 430
Score = 38.9 bits (89), Expect = 0.015
Identities = 117/548 (21%), Positives = 158/548 (28%), Gaps = 148/548 (27%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
SN GGAGGGA +PG D ++P GG
Sbjct: 77 SNNNSLGGAGGGAP---------------------------QPGPDMEQPQHGGAKDSAA 109
Query: 199 GGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDT 258
GG ++ G P +P P A GG G G
Sbjct: 110 GG-----QADPPG---PPLLSKPGDEDDAPPKMGEPA---GGRYEHPGLGALGTQQPPVA 158
Query: 259 DVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSS 318
GGGG GP + G GGPGG+A C G
Sbjct: 159 VPGGGG----------GPAAVPEFNNYYGSAAPAS------GGPGGRA--GPCFDQHGGQ 200
Query: 319 SGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHG 378
G S+S +G PG ++ PL + YP S Y GY
Sbjct: 201 QSPGMGMMHSASAAAAGA--------PG-SMDPLQNSHEGYPNSQCNHYPGY-------- 243
Query: 379 VALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCA 438
++PG+ G G G G + GA
Sbjct: 244 -----SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA---------------------- 276
Query: 439 SHLAGAAAASASCAHDPAAAAAALKSGY--------PLVYPTH--------PLHGVHSSL 482
GA A +A+ A AAA GY L P P G +SL
Sbjct: 277 ----GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASL 332
Query: 483 TAAAAAGATP--PSLAGHPLYPYGF-----MLPNDPLPHICNWVSA----NGPCDKRFAT 531
+ AAA A AG +P G L P P + ++ + + P
Sbjct: 333 SKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP 392
Query: 532 SEELLSHLRTHTAFPGTDKLLS---GYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLA 588
S+ A G G + A+A+ A A + +PG+PG
Sbjct: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452
Query: 589 LRSPHHAL-----------GLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRL 637
RS + G+ S H + P PG P GP P + G+
Sbjct: 453 GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTP 509
Query: 638 TTASALGY 645
+ + Y
Sbjct: 510 GAMAGMQY 517
Score = 37.0 bits (84), Expect = 0.057
Identities = 52/210 (24%), Positives = 67/210 (31%), Gaps = 50/210 (23%)
Query: 4 APSLSALRSSKHSGGGGGGGGGGGADPAWTSALS-------GNSSGPGPG---------- 46
A +++A ++ + GGGGGGG G A LS G GPG G
Sbjct: 278 AGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA 337
Query: 47 SSPAGSTKPFV-HAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIE 105
S AG + F PS N+L M+ + G +PEY P
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSP---------- 385
Query: 106 LDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGG--AGGGAAGDKDTKSGPLK 163
P P PS S A+ G AGG A G KD +
Sbjct: 386 ------------------SAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAA 427
Query: 164 LSDIGVEDKSSFKPYSKPGSDKKEPGGGGG 193
S + P PG+ G G
Sbjct: 428 ASPAWAAAQQRSHPAMSPGTPGPTMGRSQG 457
Score = 30.4 bits (67), Expect = 5.3
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 7 LSALRSSKHSGGGG------GGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
+S+ + S SG G G G PA++ S + SGPGPG + + + +H
Sbjct: 770 ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQ--MHGQ 827
Query: 61 PPSDP 65
PS P
Sbjct: 828 GPSQP 832
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 75.9 bits (185), Expect = 1e-13
Identities = 114/425 (26%), Positives = 152/425 (35%), Gaps = 100/425 (23%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPP--SDPLRQANRLPI 74
GG GGG G D S G + P G PP S P + + P
Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG---------PPLLSKPGDEDDAPP- 132
Query: 75 KVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPS---PS 131
KM G HP L L T P+ + A + + + G P+ P
Sbjct: 133 ---KMGEPAGGRYEHPG-LGAL-GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG 187
Query: 132 SKLSSVASNGGG-----------AGGAGGGAAGDKDTKSGPLKLSDIGVEDK--SSFKPY 178
+ GG A A GA G D PL+ S G + + + Y
Sbjct: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD----PLQNSHEGYPNSQCNHYPGY 243
Query: 179 SKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSP 238
S+PG+ GGGGGGGG GGGGGGG + G + A A +
Sbjct: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAG------------------AGGAGAGAVAAAA 285
Query: 239 GGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHP 298
++AG GGGG G GG+SA G + GGG+ +
Sbjct: 286 AAAAAAAG--------------GGGGGGYGGSSAGYGVLSSPRQQ---GGGMMM------ 322
Query: 299 DGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMT 358
GPGG S ++GS++G G A + + G T P +T
Sbjct: 323 --GPGGGGAASLSKAAAGSAAG------------GFQRFAGQNQHPSGAT--PTLNQLLT 366
Query: 359 YPGSLAGAYAG-YPPQFLPHGVALDPTKPGSLVGAQLAAA----AAGSLGCSKPAGSSPL 413
P + +Y G YP P P++P S A AAA AA +G K G+
Sbjct: 367 SPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQ-Y 425
Query: 414 AGASP 418
A ASP
Sbjct: 426 AAASP 430
Score = 38.9 bits (89), Expect = 0.015
Identities = 117/548 (21%), Positives = 158/548 (28%), Gaps = 148/548 (27%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
SN GGAGGGA +PG D ++P GG
Sbjct: 77 SNNNSLGGAGGGAP---------------------------QPGPDMEQPQHGGAKDSAA 109
Query: 199 GGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDT 258
GG ++ G P +P P A GG G G
Sbjct: 110 GG-----QADPPG---PPLLSKPGDEDDAPPKMGEPA---GGRYEHPGLGALGTQQPPVA 158
Query: 259 DVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSS 318
GGGG GP + G GGPGG+A C G
Sbjct: 159 VPGGGG----------GPAAVPEFNNYYGSAAPAS------GGPGGRA--GPCFDQHGGQ 200
Query: 319 SGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHG 378
G S+S +G PG ++ PL + YP S Y GY
Sbjct: 201 QSPGMGMMHSASAAAAGA--------PG-SMDPLQNSHEGYPNSQCNHYPGY-------- 243
Query: 379 VALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCA 438
++PG+ G G G G + GA
Sbjct: 244 -----SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA---------------------- 276
Query: 439 SHLAGAAAASASCAHDPAAAAAALKSGY--------PLVYPTH--------PLHGVHSSL 482
GA A +A+ A AAA GY L P P G +SL
Sbjct: 277 ----GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASL 332
Query: 483 TAAAAAGATP--PSLAGHPLYPYGF-----MLPNDPLPHICNWVSA----NGPCDKRFAT 531
+ AAA A AG +P G L P P + ++ + + P
Sbjct: 333 SKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP 392
Query: 532 SEELLSHLRTHTAFPGTDKLLS---GYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLA 588
S+ A G G + A+A+ A A + +PG+PG
Sbjct: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452
Query: 589 LRSPHHAL-----------GLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRL 637
RS + G+ S H + P PG P GP P + G+
Sbjct: 453 GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTP 509
Query: 638 TTASALGY 645
+ + Y
Sbjct: 510 GAMAGMQY 517
Score = 37.4 bits (85), Expect = 0.043
Identities = 99/434 (22%), Positives = 145/434 (33%), Gaps = 80/434 (18%)
Query: 4 APSLSALRSSKHSGGGGGGGGGGGADPAWTSALS-------GNSSGPGPG---------- 46
A +++A ++ + GGGGGGG G A LS G GPG G
Sbjct: 278 AGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA 337
Query: 47 SSPAGSTKPFV-HAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQP-LPSTPVSPI 104
S AG + F PS N+L M+ + G +PEY P P P S
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPSQP 395
Query: 105 ELDAKKSPLALLAQTCSQ---IGK------PDPSPSSKLSSVASNGGGAGGAGGGAAG-D 154
+ A + A Q + +GK SP+ + S+ + G G G
Sbjct: 396 QSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRS 455
Query: 155 KDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGG------GGGG-------- 200
+ + P+ + + S P+S+P PGG G G G G
Sbjct: 456 QGSPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514
Query: 201 ------------GGGGVSSEKSGFRVPSATCQPFTPRTGS-----PSSSASACSPGGMLS 243
G GVS + P + QP P PS S P +S
Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 244 SAGGAPE-------GKDDKKDTDVGGGGKGTG----GASAEGGPTG---LAHGRISCGGG 289
G GK + +D ++ + + S + PTG +S G
Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634
Query: 290 INVDVNQ-HPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQT 348
+ +Q +P P G S S +P S+ SG ++P S PG
Sbjct: 635 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS--IPGSQ 692
Query: 349 VFPLPPAGMTYPGS 362
+ P PP + S
Sbjct: 693 MPPQPPGSQSESSS 706
Score = 30.4 bits (67), Expect = 5.3
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 7 LSALRSSKHSGGGG------GGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
+S+ + S SG G G G PA++ S + SGPGPG + + + +H
Sbjct: 757 ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQ--MHGQ 814
Query: 61 PPSDP 65
PS P
Sbjct: 815 GPSQP 819
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 75.9 bits (185), Expect = 1e-13
Identities = 114/425 (26%), Positives = 152/425 (35%), Gaps = 100/425 (23%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPP--SDPLRQANRLPI 74
GG GGG G D S G + P G PP S P + + P
Sbjct: 83 GGAGGGAPQPGPDMEQPQHGGAKDSAAGGQADPPG---------PPLLSKPGDEDDAPP- 132
Query: 75 KVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPS---PS 131
KM G HP L L T P+ + A + + + G P+ P
Sbjct: 133 ---KMGEPAGGRYEHPG-LGAL-GTQQPPVAVPGGGGGPAAVPEFNNYYGSAAPASGGPG 187
Query: 132 SKLSSVASNGGG-----------AGGAGGGAAGDKDTKSGPLKLSDIGVEDK--SSFKPY 178
+ GG A A GA G D PL+ S G + + + Y
Sbjct: 188 GRAGPCFDQHGGQQSPGMGMMHSASAAAAGAPGSMD----PLQNSHEGYPNSQCNHYPGY 243
Query: 179 SKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSP 238
S+PG+ GGGGGGGG GGGGGGG + G + A A +
Sbjct: 244 SRPGAGGGGGGGGGGGGGSGGGGGGGGAG------------------AGGAGAGAVAAAA 285
Query: 239 GGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHP 298
++AG GGGG G GG+SA G + GGG+ +
Sbjct: 286 AAAAAAAG--------------GGGGGGYGGSSAGYGVLSSPRQQ---GGGMMM------ 322
Query: 299 DGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMT 358
GPGG S ++GS++G G A + + G T P +T
Sbjct: 323 --GPGGGGAASLSKAAAGSAAG------------GFQRFAGQNQHPSGAT--PTLNQLLT 366
Query: 359 YPGSLAGAYAG-YPPQFLPHGVALDPTKPGSLVGAQLAAA----AAGSLGCSKPAGSSPL 413
P + +Y G YP P P++P S A AAA AA +G K G+
Sbjct: 367 SPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQ-Y 425
Query: 414 AGASP 418
A ASP
Sbjct: 426 AAASP 430
Score = 38.9 bits (89), Expect = 0.015
Identities = 117/548 (21%), Positives = 158/548 (28%), Gaps = 148/548 (27%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
SN GGAGGGA +PG D ++P GG
Sbjct: 77 SNNNSLGGAGGGAP---------------------------QPGPDMEQPQHGGAKDSAA 109
Query: 199 GGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDT 258
GG ++ G P +P P A GG G G
Sbjct: 110 GG-----QADPPG---PPLLSKPGDEDDAPPKMGEPA---GGRYEHPGLGALGTQQPPVA 158
Query: 259 DVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSS 318
GGGG GP + G GGPGG+A C G
Sbjct: 159 VPGGGG----------GPAAVPEFNNYYGSAAPAS------GGPGGRA--GPCFDQHGGQ 200
Query: 319 SGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHG 378
G S+S +G PG ++ PL + YP S Y GY
Sbjct: 201 QSPGMGMMHSASAAAAGA--------PG-SMDPLQNSHEGYPNSQCNHYPGY-------- 243
Query: 379 VALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCA 438
++PG+ G G G G + GA
Sbjct: 244 -----SRPGAGGGGGGGGGGGGGSGGGGGGGGAGAGGA---------------------- 276
Query: 439 SHLAGAAAASASCAHDPAAAAAALKSGY--------PLVYPTH--------PLHGVHSSL 482
GA A +A+ A AAA GY L P P G +SL
Sbjct: 277 ----GAGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASL 332
Query: 483 TAAAAAGATP--PSLAGHPLYPYGF-----MLPNDPLPHICNWVSA----NGPCDKRFAT 531
+ AAA A AG +P G L P P + ++ + + P
Sbjct: 333 SKAAAGSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGSYPEYSSPSAPPPPP 392
Query: 532 SEELLSHLRTHTAFPGTDKLLS---GYPSSSSLASAAAAAMACHMHIPTSGAPGSPGTLA 588
S+ A G G + A+A+ A A + +PG+PG
Sbjct: 393 SQPQSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTM 452
Query: 589 LRSPHHAL-----------GLSSRYHPYSKSPLPTPGAPVPVPAATGPYYSPYALYGQRL 637
RS + G+ S H + P PG P GP P + G+
Sbjct: 453 GRSQGSPMDPMVMKRPQLYGMGSNPHSQPQQSSPYPGGSYGPP---GPQRYPIGIQGRTP 509
Query: 638 TTASALGY 645
+ + Y
Sbjct: 510 GAMAGMQY 517
Score = 37.4 bits (85), Expect = 0.043
Identities = 99/434 (22%), Positives = 145/434 (33%), Gaps = 80/434 (18%)
Query: 4 APSLSALRSSKHSGGGGGGGGGGGADPAWTSALS-------GNSSGPGPG---------- 46
A +++A ++ + GGGGGGG G A LS G GPG G
Sbjct: 278 AGAVAAAAAAAAAAAGGGGGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAA 337
Query: 47 SSPAGSTKPFV-HAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQP-LPSTPVSPI 104
S AG + F PS N+L M+ + G +PEY P P P S
Sbjct: 338 GSAAGGFQRFAGQNQHPSGATPTLNQLLTSPSPMMRSYGGS--YPEYSSPSAPPPPPSQP 395
Query: 105 ELDAKKSPLALLAQTCSQ---IGK------PDPSPSSKLSSVASNGGGAGGAGGGAAG-D 154
+ A + A Q + +GK SP+ + S+ + G G G
Sbjct: 396 QSQAAAAGAAAGGQQAAAGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRS 455
Query: 155 KDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGG------GGGG-------- 200
+ + P+ + + S P+S+P PGG G G G G
Sbjct: 456 QGSPMDPMVMKRPQLYGMGS-NPHSQPQQSSPYPGGSYGPPGPQRYPIGIQGRTPGAMAG 514
Query: 201 ------------GGGGVSSEKSGFRVPSATCQPFTPRTGS-----PSSSASACSPGGMLS 243
G GVS + P + QP P PS S P +S
Sbjct: 515 MQYPQQQMPPQYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 244 SAGGAPE-------GKDDKKDTDVGGGGKGTG----GASAEGGPTG---LAHGRISCGGG 289
G GK + +D ++ + + S + PTG +S G
Sbjct: 575 QEGYGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSASGS 634
Query: 290 INVDVNQ-HPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQT 348
+ +Q +P P G S S +P S+ SG ++P S PG
Sbjct: 635 TSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPAS--IPGSQ 692
Query: 349 VFPLPPAGMTYPGS 362
+ P PP + S
Sbjct: 693 MPPQPPGSQSESSS 706
Score = 30.4 bits (67), Expect = 5.3
Identities = 20/65 (30%), Positives = 30/65 (46%), Gaps = 8/65 (12%)
Query: 7 LSALRSSKHSGGGG------GGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
+S+ + S SG G G G PA++ S + SGPGPG + + + +H
Sbjct: 757 ISSFQQSNSSGTYGPQMSQYGPQGNYSRPPAYSGVPSASYSGPGPGMGISANNQ--MHGQ 814
Query: 61 PPSDP 65
PS P
Sbjct: 815 GPSQP 819
>gi|39812501 Sp8 transcription factor isoform 2 [Homo sapiens]
Length = 490
Score = 72.4 bits (176), Expect = 1e-12
Identities = 124/496 (25%), Positives = 155/496 (31%), Gaps = 152/496 (30%)
Query: 115 LLAQTCSQIGKPDPSPSSKLSSVAS----------------------------------- 139
+LA TC++IG P PSPSS S +S
Sbjct: 1 MLAATCNKIGSPSPSPSSLSDSSSSFGKGFHPWKRSSSSSSASCNVVGSSLSSFGVSGAS 60
Query: 140 -NGGGAGGAGGGAAG---------DKDTKSGPLKLSDIGVEDKS------------SFKP 177
NGG + A AA D + G S + S S P
Sbjct: 61 RNGGSSSAAAAAAAAAAAAAALVSDSFSCGGSPGSSAFSLTSSSAAAAAAAAAAAASSSP 120
Query: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSS-EKSGFRVPSATCQPFT---------PRTG 227
++ S + PG GG GGGGGGGGGG S+ + G P + T PR G
Sbjct: 121 FANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVG 180
Query: 228 SPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCG 287
S P A G DVG G ++ G H
Sbjct: 181 MAHPYESWFKPSHPGLGAAGEVGSAGASSWWDVGAGWIDVQNPNSAAALPGSLH---PAA 237
Query: 288 GGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQ 347
GG+ ++ P GG SD G S S+ SG S+ S G L+ P PG
Sbjct: 238 GGLQTSLHS-PLGG-----YNSDYSGLSHSAFSSGASSHLLSPA-GQHLMDGFKPVLPG- 289
Query: 348 TVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKP 407
+YP S AG A + S G S P
Sbjct: 290 ----------SYPDSAPSPLAG-------------------------AGGSMLSAGPSAP 314
Query: 408 AGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYP 467
G SP + A S + C P C A L PA A+ K
Sbjct: 315 LGGSPRSSARRYS--GRATCDCPNCQE---AERLG------------PAGASLRRKG--- 354
Query: 468 LVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWVSANGPCDK 527
LH H + L H + G P +CNW+ C K
Sbjct: 355 -------LHSCH--IPGCGKVYGKTSHLKAHLRWHTG------ERPFVCNWLF----CGK 395
Query: 528 RFATSEELLSHLRTHT 543
RF S+EL HLRTHT
Sbjct: 396 RFTRSDELQRHLRTHT 411
Score = 42.4 bits (98), Expect = 0.001
Identities = 56/244 (22%), Positives = 85/244 (34%), Gaps = 36/244 (14%)
Query: 102 SPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAG----DKDT 157
S L + + A A + P + S + +GG GG GGG G +D
Sbjct: 96 SAFSLTSSSAAAAAAAAAAAASSSPFANDYSVFQAPGVSGGSGGGGGGGGGGSSAHSQDG 155
Query: 158 KSGPLKLSDI--GVEDKSSFKP---YSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGF 212
P+ +S + V+ P + P +P G G G G G S +
Sbjct: 156 SHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHPGLGAAGEVGSAGA----SSWW 211
Query: 213 RVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASA 272
V + P +++A PG + +AGG + +GG G S
Sbjct: 212 DVGAGWIDVQNP-------NSAAALPGSLHPAAGGL----QTSLHSPLGGYNSDYSGLSH 260
Query: 273 EGGPTGLAHGRISCGGGINVD------VNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAP 326
+G + +S G +D +PD P S G+ GS +GPSAP
Sbjct: 261 SAFSSGASSHLLSPAGQHLMDGFKPVLPGSYPDSAP------SPLAGAGGSMLSAGPSAP 314
Query: 327 TSSS 330
S
Sbjct: 315 LGGS 318
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/49 (38%), Positives = 22/49 (44%)
Query: 294 VNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSP 342
V H GG GG + GS GG GS + S SA S L+ P P
Sbjct: 435 VKTHSGGGGGGGSAGSGSGGKKGSDTDSEHSAAGSPPCHSPELLQPPEP 483
Score = 32.0 bits (71), Expect = 1.8
Identities = 13/24 (54%), Positives = 14/24 (58%)
Query: 185 KKEPGGGGGGGGGGGGGGGGVSSE 208
K GGGGGGG G G GG S+
Sbjct: 436 KTHSGGGGGGGSAGSGSGGKKGSD 459
Score = 30.4 bits (67), Expect = 5.3
Identities = 18/54 (33%), Positives = 23/54 (42%), Gaps = 11/54 (20%)
Query: 15 HSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHA---VPPSDP 65
HSGGGGGGG G SG G S + + P H+ + P +P
Sbjct: 438 HSGGGGGGGSAGSG--------SGGKKGSDTDSEHSAAGSPPCHSPELLQPPEP 483
Score = 30.0 bits (66), Expect = 6.9
Identities = 19/58 (32%), Positives = 24/58 (41%), Gaps = 8/58 (13%)
Query: 16 SGGGGGGGGGGGA--------DPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDP 65
SGGGGGGGGGG + P + S + + G G P+ PS P
Sbjct: 137 SGGGGGGGGGGSSAHSQDGSHQPVFISKVHTSVDGLQGIYPRVGMAHPYESWFKPSHP 194
Score = 29.6 bits (65), Expect = 9.0
Identities = 13/24 (54%), Positives = 15/24 (62%)
Query: 4 APSLSALRSSKHSGGGGGGGGGGG 27
A S ++ SGG GGGGGGGG
Sbjct: 122 ANDYSVFQAPGVSGGSGGGGGGGG 145
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 68.6 bits (166), Expect = 2e-11
Identities = 60/177 (33%), Positives = 73/177 (41%), Gaps = 30/177 (16%)
Query: 175 FKPYSKPGSDKKEP---GGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSS 231
F+P G+ P GGGGG G GGGGGGGV G V SA + P+
Sbjct: 65 FEPADPEGAGLLLPPPGGGGGGSAGSGGGGGGGVGVP--GLLVGSAGVGGDPSLSSLPAG 122
Query: 232 SA------SACSPGGMLSSAGGAPEGKDDKK------------DTDVGGGGKGTGGASAE 273
+A + S G + S+GG DD D G G G +AE
Sbjct: 123 AALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVADPRASPGAGGGGAKAAE 182
Query: 274 GGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSS 330
G HG G +V GG GG + GS GG GS SGSG S+ +SSS
Sbjct: 183 GCSNAHLHG------GASVPPGGLGGGGGGGSSSGSS-GGGGGSGSGSGGSSSSSSS 232
Score = 39.3 bits (90), Expect = 0.011
Identities = 50/195 (25%), Positives = 59/195 (30%), Gaps = 51/195 (26%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIK 75
S G GGGGGGG P +G P S PAG+
Sbjct: 87 SAGSGGGGGGGVGVPGLLVGSAGVGGDPSLSSLPAGAA---------------------- 124
Query: 76 VLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLS 135
L + G + SP + + L L A G DP S
Sbjct: 125 ----LCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRA------GVADPRASP--- 171
Query: 136 SVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGG 195
GAGG G AA S+ + +S P G G GG
Sbjct: 172 -------GAGGGGAKAAEG---------CSNAHLHGGASVPPGGLGGGGGGGSSSGSSGG 215
Query: 196 GGGGGGGGGVSSEKS 210
GGG G G G SS S
Sbjct: 216 GGGSGSGSGGSSSSS 230
Score = 38.9 bits (89), Expect = 0.015
Identities = 46/138 (33%), Positives = 56/138 (40%), Gaps = 43/138 (31%)
Query: 127 DPSPSS---------KLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP 177
DPS SS K AS G A +GG + D D+ + GV D P
Sbjct: 113 DPSLSSLPAGAALCLKYGESASRGSVAESSGGEQSPDDDSDGRCELVLRAGVAD-----P 167
Query: 178 YSKPGSDKKEPGGGG-------------GG-----GGGGGGGGGGVSSEKSGFRVPSATC 219
+ PG+ GGGG GG GG GGGGGGG SS SG S +
Sbjct: 168 RASPGA-----GGGGAKAAEGCSNAHLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGS- 221
Query: 220 QPFTPRTGSPSSSASACS 237
+G SSS+S+ S
Sbjct: 222 -----GSGGSSSSSSSSS 234
Score = 34.3 bits (77), Expect = 0.37
Identities = 16/36 (44%), Positives = 21/36 (58%)
Query: 18 GGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
GG GGGGGGG+ + G+ SG G SS + S+
Sbjct: 198 GGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSS 233
Score = 31.6 bits (70), Expect = 2.4
Identities = 16/38 (42%), Positives = 20/38 (52%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTK 54
G GGGGGGG + + SG+ SG SS + S K
Sbjct: 199 GLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKK 236
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 64.3 bits (155), Expect = 3e-10
Identities = 121/448 (27%), Positives = 146/448 (32%), Gaps = 118/448 (26%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIK 75
+G GG GG G P + +G PGP + P G PP
Sbjct: 593 NGERGGPGGPGPQGPPGKNGETGPQGPPGP-TGPGGDKGD---TGPPG------------ 636
Query: 76 VLKMLTARTGHILHPEYLQPLPSTPVSPIE--LDAKKSPLALLAQTCSQIGKPDPSPSSK 133
P+ LQ LP T P E + P + GK D +
Sbjct: 637 --------------PQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGE 682
Query: 134 -----LSSVASNGGGAG--------GAGG-----GAAGDKDTKSGPLKLSDIGVEDKSSF 175
L+ GGAG GA G GAAG + P + +G
Sbjct: 683 RGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPG---- 738
Query: 176 KPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASA 235
P DK EPGG G G G K G R P+ P P G P
Sbjct: 739 -----PKGDKGEPGGPGADGVPG----------KDGPRGPTGPIGPPGP-AGQPGDKGEG 782
Query: 236 CSPG--GMLSSAGGAPE-------------GKDDKKDTDVGGGGKGTGGASAEGGPTGLA 280
+PG G+ G E G + G G +G G EGGP G+A
Sbjct: 783 GAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVA 842
Query: 281 -----HGRISCGGGINVDVNQHPDGGPGGKALGSDCG--GSSGSSSGSGPSAPTSSSVLG 333
G G V + GGPG G G GS+ GP P+
Sbjct: 843 GPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSG----- 897
Query: 334 SGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQ 393
SP K G P PAG T GA G P P G A P + GS GAQ
Sbjct: 898 -------SPGKDG----PPGPAGNT------GA-PGSPGVSGPKGDAGQPGEKGS-PGAQ 938
Query: 394 LAAAAAGSLGCSKPAGSSPLAGASPPSV 421
A G LG + G+ LAG PP +
Sbjct: 939 GPPGAPGPLGIAGITGARGLAG--PPGM 964
Score = 62.4 bits (150), Expect = 1e-09
Identities = 109/445 (24%), Positives = 136/445 (30%), Gaps = 74/445 (16%)
Query: 4 APSLSALRSSKHSGGGGGGGG--GGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVP 61
AP L R G G G GG +P +G PGP + P V
Sbjct: 406 APGLMGARGPPGPAGANGAPGLRGGAGEPG----KNGAKGEPGPRGERGEAGIPGVPGAK 461
Query: 62 --------PSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPL 113
P +P AN LP G P + P P + +K P
Sbjct: 462 GEDGKDGSPGEP--GANGLP--------GAAGERGAPGF-----RGPAGPNGIPGEKGP- 505
Query: 114 ALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAG-----GGAAGD-KDTKSGPLKLSDI 167
+ G P P+ + G GG G G G D K GP
Sbjct: 506 ------AGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPP----- 554
Query: 168 GVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTG 227
G + +S P + +PG G G G G G + E+ G P P
Sbjct: 555 GSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGET 614
Query: 228 SPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCG 287
P PGG G P G + GG G G E GP G A + G
Sbjct: 615 GPQGPPGPTGPGGDKGDTG--PPGPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPG 672
Query: 288 GGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSP----Y 343
G D + GP G A G+ G G+GP P G G P P
Sbjct: 673 G--KGDAGAPGERGPPGLA------GAPGLRGGAGPPGPEG----GKGAAGPPGPPGAAG 720
Query: 344 KPGQTVFPLPPAGMTYPGSLAG-------AYAGYPPQFLPHGVA--LDPTKPGSLVGAQL 394
PG P G+ PG G P + P G + P P G +
Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKG 780
Query: 395 AAAAAGSLGCSKPAGSSPLAGASPP 419
A G G + P GS G + P
Sbjct: 781 EGGAPGLPGIAGPRGSPGERGETGP 805
Score = 59.7 bits (143), Expect = 8e-09
Identities = 108/417 (25%), Positives = 136/417 (32%), Gaps = 49/417 (11%)
Query: 5 PSLSALRSSKHSGGGGGGGGGGGADPA-WTSALSGNSSGPGPGSSPA--GSTKPFVHAVP 61
P ++ + S GG G G GA +GN PGP SP G P +
Sbjct: 854 PGPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGA 913
Query: 62 PSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCS 121
P P + K + G P P P P P+ + L
Sbjct: 914 PGSP-------GVSGPKGDAGQPGEKGSPGAQGP-PGAP-GPLGIAGITGARGLAGPP-- 962
Query: 122 QIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKP 181
G P P S V G G G +G++ GP L + +P
Sbjct: 963 --GMPGPRGSPGPQGVKGESGKPGA--NGLSGERGPP-GPQGLPGLA-------GTAGEP 1010
Query: 182 GSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGM 241
G D PG G G G GG G E P A P P P+ + G
Sbjct: 1011 GRDGN-PGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGP 1069
Query: 242 LSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGG 301
A GAP G + G +G G + E G G+ R G + G
Sbjct: 1070 AGPA-GAP-GPAGSRGAPGPQGPRGDKGETGERGAAGIKGHR-----GFPGNPGAPGSPG 1122
Query: 302 PGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPG 361
P G+ G +G GPS P SG P+ P PG P G
Sbjct: 1123 PAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT-SGHPGPIGP--PG-------PRGNRGER 1172
Query: 362 SLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASP 418
G+ G+P Q P G P PG G AAA AG +G K G +P G P
Sbjct: 1173 GSEGS-PGHPGQPGPPG---PPGAPGPCCGGVGAAAIAG-IGGEKAGGFAPYYGDEP 1224
Score = 48.5 bits (114), Expect = 2e-05
Identities = 107/427 (25%), Positives = 141/427 (33%), Gaps = 45/427 (10%)
Query: 18 GGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPLRQANRLPIKVL 77
G G G G P +G+ PG SP P + P+ P + + +
Sbjct: 101 GQGPQGPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDV 160
Query: 78 KMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSV 137
K A G +P P P P P SP G P +
Sbjct: 161 KSGVAVGGLAGYPGPAGP-PGPPGPPGTSGHPGSP--------GSPGYQGPPGEPGQAGP 211
Query: 138 ASNGGGAGGAGGGAAGDKDTKSG-PLKLSDIGVEDKSSFK-PYSKPG--SDKKEPGGGGG 193
+ G G G KD +SG P + + G+ K P PG K G G
Sbjct: 212 SGPPGPPGAIGPSGPAGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGR 271
Query: 194 GGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKD 253
G G G G+ E +G + P PR G+P PG A GA G D
Sbjct: 272 NGEKGETGAPGLKGE-NGLPGENGAPGPMGPR-GAPGERGRPGLPG-----AAGA-RGND 323
Query: 254 DKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGG--GINVDVNQHPDGGPGGKALGSDC 311
+ +D G G G + G G A G + G G N Q + GP G A
Sbjct: 324 GARGSDGQPGPPGPPGTAGFPGSPG-AKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGP 382
Query: 312 GGS---SGSSSGSGPSAPTSSSVLGS-GLVAPVSPYKP-GQTVFPLPPAGMTYPGSLA-- 364
G +GS G G P + + G+ GL+ P P G P G PG
Sbjct: 383 PGPPGINGSPGGKGEMGP--AGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAK 440
Query: 365 -----------GAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPL 413
G P G P +PG+ G AA G+ G PAG + +
Sbjct: 441 GEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGA-NGLPGAAGERGAPGFRGPAGPNGI 499
Query: 414 AGASPPS 420
G P+
Sbjct: 500 PGEKGPA 506
Score = 47.8 bits (112), Expect = 3e-05
Identities = 75/294 (25%), Positives = 93/294 (31%), Gaps = 38/294 (12%)
Query: 143 GAGGAGG--GAAGDKDTKSGPLKLSDIGVEDKSSFK----PYSKPGSD-----KKEPGGG 191
GA GA G GA G P G K P PGS+ + EPG
Sbjct: 315 GAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQ 374
Query: 192 GGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEG 251
G G G G G++ G G + +PG M + P G
Sbjct: 375 GHAGAQGPPGPPGINGSPGG--------------KGEMGPAGIPGAPGLMGARGPPGPAG 420
Query: 252 KDDKKDTDVGGGGKGTGGASAEGGPTGL--AHGRISCGGGINVDVNQHPDGGPGGKALGS 309
+ G G G GA E GP G G G D G PG L
Sbjct: 421 ANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPG 480
Query: 310 DCG--GSSGSSSGSGPSA-PTSSSVLGS-GLVAPVSPY----KPGQTVFPLPPAGMTYPG 361
G G+ G +GP+ P G G P P +PG+ P P PG
Sbjct: 481 AAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPG 540
Query: 362 SLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAG 415
S G + P P G + +PG G G +G P G+ G
Sbjct: 541 SPGGPGSDGKPG--PPGSQGESGRPGP-PGPSGPRGQPGVMGFPGPKGNDGAPG 591
Score = 40.0 bits (92), Expect = 0.007
Identities = 50/190 (26%), Positives = 67/190 (35%), Gaps = 28/190 (14%)
Query: 181 PGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGG 240
P + + P G G G G G G+ +P QP +P GSP P G
Sbjct: 92 PTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPG---QPGSP--GSPG-------PPG 139
Query: 241 MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGL-----AHGRISCGGGINVDVN 295
+ S P+ + D+ G GG + GP G G G
Sbjct: 140 ICESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGY 199
Query: 296 QHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPA 355
Q P G P G+A S G G+ SGP+ S P +PG+ P PP
Sbjct: 200 QGPPGEP-GQAGPSGPPGPPGAIGPSGPAGKDGES---------GRPGRPGERGLPGPP- 248
Query: 356 GMTYPGSLAG 365
G+ P + G
Sbjct: 249 GIKGPAGIPG 258
>gi|21264565 AT rich interactive domain 1A isoform a [Homo sapiens]
Length = 2285
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/459 (23%), Positives = 148/459 (32%), Gaps = 113/459 (24%)
Query: 121 SQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSF----K 176
S +G P P P S+L AGG AA + G +K + G E + +
Sbjct: 11 SSLGNPPPPPPSELKKAEQQQREE--AGGEAAAAAAAERGEMKAA-AGQESEGPAVGPPQ 67
Query: 177 PYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASAC 236
P K D E GGGGGGG G GGG G +
Sbjct: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSN----------------------- 104
Query: 237 SPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAE---------------GGPTGLAH 281
+AG P ++ + GGGG + G A G P G +
Sbjct: 105 ------GNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP 158
Query: 282 GRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVS 341
++ PG AL S GG G +GP + + +
Sbjct: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQS--GGGGGLEPYAGPQQNSHDHGFPN---HQYN 213
Query: 342 PYKPGQTVFPLP--------PAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQ 393
Y P ++ +P P P G T PGS A A AG P P A + S AQ
Sbjct: 214 SYYPNRSAYPPPAPAYALSSPRGGT-PGSGAAAAAGSKPP--PSSSASASSSSSSF--AQ 268
Query: 394 LAAAAAGSLGCSKPAGSSPLAGASP--------PS----------------VMTASLCRD 429
A G G S G +P A+P PS +
Sbjct: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKG 328
Query: 430 PYCLSYHCASHLAGAAAASASCA-------HDPAAAAAALKSGYPLV---YPTHPL---- 475
P ++ C A AAAA+A+ H P + ++ G PL P+ P+
Sbjct: 329 PADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMG 388
Query: 476 ------HGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLP 508
+G + + + P G+P PYG P
Sbjct: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427
Score = 55.8 bits (133), Expect = 1e-07
Identities = 104/413 (25%), Positives = 129/413 (31%), Gaps = 81/413 (19%)
Query: 13 SKHSGGGGGGGGGGGADPAWTSALSGNSSGPGP-----------------GSSPAGSTKP 55
++ +GGGGGGG G G P L ++ GP GSS P
Sbjct: 77 AESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPP 136
Query: 56 FVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEY-LQPLPSTPVSPIELDAKKSPLA 114
A P + + + A + H ++ Q P P A
Sbjct: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYA 196
Query: 115 LLAQTCSQIGKPD---------------PSPSSKLSSVASNGGGAGGAGGGAAGDKDTKS 159
Q G P+ P+P+ LSS GG G AAG K S
Sbjct: 197 GPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS--PRGGTPGSGAAAAAGSKPPPS 254
Query: 160 GPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATC 219
SS S S ++ G GGGG GGG P T
Sbjct: 255 -------------SSASASSSSSSFAQQRFGAMGGGGPSAAGGG----------TPQPTA 291
Query: 220 QPFTPRTGSPSSSASACS--PGGMLSSA---GGAPEGKDDKKDTDVGGGGKGTGGASAEG 274
P + + SSA PGG S GGA +G D G A+A G
Sbjct: 292 TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351
Query: 275 GPTGLAHGR-----ISCGGGINVDVNQHPDG--GPGGKALGSDCGGSSGSSSGSGPSAPT 327
G +H S GGG + P GK GG++ S G P
Sbjct: 352 GAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQG---PP 408
Query: 328 SSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAG--YPPQFLPHG 378
S G G P PY QT P MT G A G Y Q P+G
Sbjct: 409 SGPQQGHGY--PGQPY-GSQTPQRYP---MTMQGRAQSAMGGLSYTQQIPPYG 455
Score = 30.0 bits (66), Expect = 6.9
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 17/86 (19%)
Query: 390 VGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASA 449
+ AQ+A AAA SLG P S L A A G AAA+A
Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----------------GEAAAAA 43
Query: 450 SCAHDPAAAAAALKSGYPLVYPTHPL 475
+ AAA +S P V P PL
Sbjct: 44 AAERGEMKAAAGQESEGPAVGPPQPL 69
>gi|21264575 AT rich interactive domain 1A isoform b [Homo sapiens]
Length = 2068
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/459 (23%), Positives = 148/459 (32%), Gaps = 113/459 (24%)
Query: 121 SQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSF----K 176
S +G P P P S+L AGG AA + G +K + G E + +
Sbjct: 11 SSLGNPPPPPPSELKKAEQQQREE--AGGEAAAAAAAERGEMKAA-AGQESEGPAVGPPQ 67
Query: 177 PYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASAC 236
P K D E GGGGGGG G GGG G +
Sbjct: 68 PLGKELQDGAESNGGGGGGGAGSGGGPGAEPDLKNSN----------------------- 104
Query: 237 SPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAE---------------GGPTGLAH 281
+AG P ++ + GGGG + G A G P G +
Sbjct: 105 ------GNAGPRPALNNNLTEPPGGGGGGSSDGVGAPPHSAAAALPPPAYGFGQPYGRSP 158
Query: 282 GRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVS 341
++ PG AL S GG G +GP + + +
Sbjct: 159 SAVAAAAAAVFHQQHGGQQSPGLAALQS--GGGGGLEPYAGPQQNSHDHGFPN---HQYN 213
Query: 342 PYKPGQTVFPLP--------PAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQ 393
Y P ++ +P P P G T PGS A A AG P P A + S AQ
Sbjct: 214 SYYPNRSAYPPPAPAYALSSPRGGT-PGSGAAAAAGSKPP--PSSSASASSSSSSF--AQ 268
Query: 394 LAAAAAGSLGCSKPAGSSPLAGASP--------PS----------------VMTASLCRD 429
A G G S G +P A+P PS +
Sbjct: 269 QRFGAMGGGGPSAAGGGTPQPTATPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKG 328
Query: 430 PYCLSYHCASHLAGAAAASASCA-------HDPAAAAAALKSGYPLV---YPTHPL---- 475
P ++ C A AAAA+A+ H P + ++ G PL P+ P+
Sbjct: 329 PADMASQCWGAAAAAAAAAAASGGAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMG 388
Query: 476 ------HGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLP 508
+G + + + P G+P PYG P
Sbjct: 389 KMRPQPYGGTNPYSQQQGPPSGPQQGHGYPGQPYGSQTP 427
Score = 55.8 bits (133), Expect = 1e-07
Identities = 104/413 (25%), Positives = 129/413 (31%), Gaps = 81/413 (19%)
Query: 13 SKHSGGGGGGGGGGGADPAWTSALSGNSSGPGP-----------------GSSPAGSTKP 55
++ +GGGGGGG G G P L ++ GP GSS P
Sbjct: 77 AESNGGGGGGGAGSGGGPGAEPDLKNSNGNAGPRPALNNNLTEPPGGGGGGSSDGVGAPP 136
Query: 56 FVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEY-LQPLPSTPVSPIELDAKKSPLA 114
A P + + + A + H ++ Q P P A
Sbjct: 137 HSAAAALPPPAYGFGQPYGRSPSAVAAAAAAVFHQQHGGQQSPGLAALQSGGGGGLEPYA 196
Query: 115 LLAQTCSQIGKPD---------------PSPSSKLSSVASNGGGAGGAGGGAAGDKDTKS 159
Q G P+ P+P+ LSS GG G AAG K S
Sbjct: 197 GPQQNSHDHGFPNHQYNSYYPNRSAYPPPAPAYALSS--PRGGTPGSGAAAAAGSKPPPS 254
Query: 160 GPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATC 219
SS S S ++ G GGGG GGG P T
Sbjct: 255 -------------SSASASSSSSSFAQQRFGAMGGGGPSAAGGG----------TPQPTA 291
Query: 220 QPFTPRTGSPSSSASACS--PGGMLSSA---GGAPEGKDDKKDTDVGGGGKGTGGASAEG 274
P + + SSA PGG S GGA +G D G A+A G
Sbjct: 292 TPTLNQLLTSPSSARGYQGYPGGDYSGGPQDGGAGKGPADMASQCWGAAAAAAAAAAASG 351
Query: 275 GPTGLAHGR-----ISCGGGINVDVNQHPDG--GPGGKALGSDCGGSSGSSSGSGPSAPT 327
G +H S GGG + P GK GG++ S G P
Sbjct: 352 GAQQRSHHAPMSPGSSGGGGQPLARTPQPSSPMDQMGKMRPQPYGGTNPYSQQQG---PP 408
Query: 328 SSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAG--YPPQFLPHG 378
S G G P PY QT P MT G A G Y Q P+G
Sbjct: 409 SGPQQGHGY--PGQPY-GSQTPQRYP---MTMQGRAQSAMGGLSYTQQIPPYG 455
Score = 30.0 bits (66), Expect = 6.9
Identities = 28/86 (32%), Positives = 33/86 (38%), Gaps = 17/86 (19%)
Query: 390 VGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASA 449
+ AQ+A AAA SLG P S L A A G AAA+A
Sbjct: 1 MAAQVAPAAASSLGNPPPPPPSELKKAEQQQREEAG-----------------GEAAAAA 43
Query: 450 SCAHDPAAAAAALKSGYPLVYPTHPL 475
+ AAA +S P V P PL
Sbjct: 44 AAERGEMKAAAGQESEGPAVGPPQPL 69
>gi|7710121 engrailed homeobox 2 [Homo sapiens]
Length = 333
Score = 61.6 bits (148), Expect = 2e-09
Identities = 61/219 (27%), Positives = 87/219 (39%), Gaps = 51/219 (23%)
Query: 127 DPSPSSKLSSV-------ASNGGGAGGAGGGAAGDKDT-----------------KSGPL 162
DP P ++V +S GGG+GG GG + G+ DT P
Sbjct: 5 DPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPH 64
Query: 163 KLSDIGVED--KSSFKPYSKPGSDKKEPGGGGGGGGGG--------GGGGGGVSSE--KS 210
++++ +++ + F G+ GGG GGG GG GGGG G S + S
Sbjct: 65 RITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGS 124
Query: 211 GFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGA 270
G R P P P G P +A + SPG +G+ K + GG K G
Sbjct: 125 GSREPRQN-PPCAPGAGGPLPAAGSDSPG----------DGEGGSKTLSLHGGAKKGGD- 172
Query: 271 SAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGS 309
GGP + GGG ++ V+ D G LG+
Sbjct: 173 --PGGPLDGSLKARGLGGG-DLSVSSDSDSSQAGANLGA 208
Score = 46.2 bits (108), Expect = 9e-05
Identities = 51/180 (28%), Positives = 63/180 (35%), Gaps = 52/180 (28%)
Query: 190 GGGGGGGGGGGGGGGVSSEKSGFRVPSATCQP-----------------FTPRTGSPSSS 232
GGG GGGGG G + + +P+ P P G +
Sbjct: 26 GGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDA 85
Query: 233 ASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGAS-AEGGPTGLAHGRISCGGGIN 291
+ C+ G GG GGG G GGAS AEGG G A G G +
Sbjct: 86 GTCCAGAG-----GGR------------GGGAGGEGGASGAEGG--GGAGGSEQLLGSGS 126
Query: 292 VDVNQHPDGGPGG----KALGSDC-----GGS------SGSSSGSGPSAPTSSSVLGSGL 336
+ Q+P PG A GSD GGS G+ G P P S+ GL
Sbjct: 127 REPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGL 186
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/122 (36%), Positives = 51/122 (41%), Gaps = 14/122 (11%)
Query: 300 GGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVS--PYKPGQTVFPLPPAGM 357
GG GG A G GG+SG+ G G A S +LGSG P P PG PLP AG
Sbjct: 94 GGRGGGAGGE--GGASGAEGGGG--AGGSEQLLGSGSREPRQNPPCAPG-AGGPLPAAGS 148
Query: 358 TYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAA--AAAGSLGCSKPAGSSPLAG 415
PG G HG A PG + L A G L S + SS AG
Sbjct: 149 DSPGDGEGG----SKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQ-AG 203
Query: 416 AS 417
A+
Sbjct: 204 AN 205
Score = 30.4 bits (67), Expect = 5.3
Identities = 17/50 (34%), Positives = 23/50 (46%), Gaps = 2/50 (4%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDP 65
+G GGG GGG G + + A G +G +GS +P PP P
Sbjct: 90 AGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREP--RQNPPCAP 137
>gi|51479192 ring finger protein 1 [Homo sapiens]
Length = 406
Score = 60.5 bits (145), Expect = 5e-09
Identities = 69/218 (31%), Positives = 83/218 (38%), Gaps = 33/218 (15%)
Query: 128 PSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKE 187
P P S ++ S G G G G G D + S P S PG K
Sbjct: 159 PIPGSDQTTTMSGGEGEPGEGEGDGEDVSSDSAP----------------DSAPGPAPKR 202
Query: 188 PGGGGG-------GGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGG 240
P GGG GGGG GG GGG SE SG R T T SP + S PGG
Sbjct: 203 PRGGGAGGSSVGTGGGGTGGVGGGAGSEDSGDR--GGTLGGGTLGPPSPPGAPSPPEPGG 260
Query: 241 MLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDG 300
+ +K + K TG A+ + LA RI+ + + G
Sbjct: 261 EIELVFRPHPLLVEKGEYCQTRYVKTTGNATVDHLSKYLAL-RIALERRQQQEAGE--PG 317
Query: 301 GPGGKAL---GSD-CGG-SSGSSSGSGPSAPTSSSVLG 333
GPGG A G D CGG G+ G GP P S+ G
Sbjct: 318 GPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEG 355
Score = 38.9 bits (89), Expect = 0.015
Identities = 49/174 (28%), Positives = 65/174 (37%), Gaps = 19/174 (10%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGP--GPGSSPAGSTKPFVHAVPPSDPLRQA 69
SS +GGGG GG GGGA + G G GP S P + P P +
Sbjct: 211 SSVGTGGGGTGGVGGGAGSEDSGDRGGTLGGGTLGPPSPPGAPSPP-----EPGGEIELV 265
Query: 70 NR-LPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDP 128
R P+ V K G Y++ + V + +K L + + Q +P
Sbjct: 266 FRPHPLLVEK------GEYCQTRYVKTTGNATVDHL---SKYLALRIALERRQQQEAGEP 316
Query: 129 SPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPG 182
+S G GG GGGA G D P S GV +K + Y PG
Sbjct: 317 GGPGGGASDTGGPDGCGGEGGGAGGG-DGPEEPALPSLEGVSEK-QYTIYIAPG 368
Score = 31.2 bits (69), Expect = 3.1
Identities = 15/50 (30%), Positives = 18/50 (36%)
Query: 11 RSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAV 60
R + G GG GGG +D G G G G P P + V
Sbjct: 307 RRQQQEAGEPGGPGGGASDTGGPDGCGGEGGGAGGGDGPEEPALPSLEGV 356
>gi|126352446 elastin isoform d precursor [Homo sapiens]
Length = 711
Score = 60.1 bits (144), Expect = 6e-09
Identities = 120/428 (28%), Positives = 147/428 (34%), Gaps = 81/428 (18%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGA--AGDKDTKSGPLKLSDIGV-EDKSSFKPYSK 180
G P P V G G G GGGA G K K P L+ G+ +F +
Sbjct: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87
Query: 181 PGSDKKEPGG-------------GGGGGGGGGGGGGGVSSEKS--GFRV--PSATCQP-F 222
PG+ PGG G G GG G GG GVS+ S G V P A +P
Sbjct: 88 PGA--LVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGK 145
Query: 223 TPRTGSPSSSASACSPGGMLSSAG---GAPEGKDDK-KDTDVGGGGKGTGGASAEGGP-T 277
P G P PG G G P G K K VGG G G GGP
Sbjct: 146 VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 205
Query: 278 GLAHG------RISCGGGINVDVNQHPDG-GPGGKALGSDCGGSSGSSSGSG-------P 323
G+ G ++ G G+ + P G GPGG A G +G +G+G
Sbjct: 206 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGTGVGPQAAAA 262
Query: 324 SAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDP 383
+A +++ G+G A V P G V P P + G +AG G P A
Sbjct: 263 AAAKAAAKFGAG-AAGVLPGVGGAGV-PGVPGAIPGIGGIAG--VGTPAAAAAAAAAAKA 318
Query: 384 TKPGSLVGAQLAAAAAGSLGCSKPAGSSP---LAGASPPSVMTASLCRDPYCLSYHCASH 440
K G+ G G P P + GA P V A +
Sbjct: 319 AKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI-------------- 364
Query: 441 LAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATP-------- 492
AA AAA AA K+ Y P GV T AG P
Sbjct: 365 ---PGAAVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 418
Query: 493 -PSLAGHP 499
P +AG P
Sbjct: 419 IPGVAGVP 426
Score = 50.1 bits (118), Expect = 6e-06
Identities = 79/296 (26%), Positives = 108/296 (36%), Gaps = 35/296 (11%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGS 183
G P ++K ++ A+ G G G G +G +GV PG
Sbjct: 371 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--------GIPGV 422
Query: 184 DKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLS 243
G GG G GG G G+S E A + + +A+ + G++
Sbjct: 423 AGVP--GVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 480
Query: 244 SAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG-RISCGGGINVDVNQHPDGGP 302
G AP G G G A G GLA G ++ G G+ V P GP
Sbjct: 481 GVGVAP------------GVGVAPGVGVAPG--VGLAPGVGVAPGVGVAPGVGVAPGIGP 526
Query: 303 GGKALGSDCGGSSGSSSGSGPSAPTSSSV--LGSGLVAP---VSPYKPGQTVFPLPPAGM 357
GG A + + + +A + + LG G+ P V PG V P
Sbjct: 527 GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 586
Query: 358 TYPGSLAGA----YAGYPPQFLPHGVALDPTK-PGSLVGAQLAAAAAGSLGCSKPA 408
PG+LA A Y P L AL PG +VGA AAAAA + +K A
Sbjct: 587 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 642
Score = 40.8 bits (94), Expect = 0.004
Identities = 83/370 (22%), Positives = 116/370 (31%), Gaps = 61/370 (16%)
Query: 135 SSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP--YSKPGSDKKEPGGGG 192
+ V G GGA G G GP +G K+ P Y P + K P G G
Sbjct: 178 AGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 236
Query: 193 GGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGK 252
GG G G K+G+ + + +++ G+L GGA
Sbjct: 237 PGGVAGAAG-------KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 289
Query: 253 DDKKDTDVGG-GGKGT------GGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGK 305
+GG G GT A+A+ G A G + G G V P G G
Sbjct: 290 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV 349
Query: 306 AL---GSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGS 362
+ G +G + P + + + A +PG V +P G+
Sbjct: 350 GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG---- 405
Query: 363 LAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVM 422
AG + G+ G VG A +G G P G SP +
Sbjct: 406 -AGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ- 447
Query: 423 TASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSL 482
A AAA +A AAAAA + + P GV +
Sbjct: 448 -------------------AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 488
Query: 483 TAAAAAGATP 492
A G P
Sbjct: 489 GVAPGVGVAP 498
>gi|126352322 elastin isoform c precursor [Homo sapiens]
Length = 692
Score = 60.1 bits (144), Expect = 6e-09
Identities = 120/428 (28%), Positives = 147/428 (34%), Gaps = 81/428 (18%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGA--AGDKDTKSGPLKLSDIGV-EDKSSFKPYSK 180
G P P V G G G GGGA G K K P L+ G+ +F +
Sbjct: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87
Query: 181 PGSDKKEPGG-------------GGGGGGGGGGGGGGVSSEKS--GFRV--PSATCQP-F 222
PG+ PGG G G GG G GG GVS+ S G V P A +P
Sbjct: 88 PGA--LVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSAAPSVPGAVVPQPGAGVKPGK 145
Query: 223 TPRTGSPSSSASACSPGGMLSSAG---GAPEGKDDK-KDTDVGGGGKGTGGASAEGGP-T 277
P G P PG G G P G K K VGG G G GGP
Sbjct: 146 VPGVGLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQP 205
Query: 278 GLAHG------RISCGGGINVDVNQHPDG-GPGGKALGSDCGGSSGSSSGSG-------P 323
G+ G ++ G G+ + P G GPGG A G +G +G+G
Sbjct: 206 GVPLGYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGTGVGPQAAAA 262
Query: 324 SAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDP 383
+A +++ G+G A V P G V P P + G +AG G P A
Sbjct: 263 AAAKAAAKFGAG-AAGVLPGVGGAGV-PGVPGAIPGIGGIAG--VGTPAAAAAAAAAAKA 318
Query: 384 TKPGSLVGAQLAAAAAGSLGCSKPAGSSP---LAGASPPSVMTASLCRDPYCLSYHCASH 440
K G+ G G P P + GA P V A +
Sbjct: 319 AKYGAAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI-------------- 364
Query: 441 LAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATP-------- 492
AA AAA AA K+ Y P GV T AG P
Sbjct: 365 ---PGAAVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGG 418
Query: 493 -PSLAGHP 499
P +AG P
Sbjct: 419 IPGVAGVP 426
Score = 47.4 bits (111), Expect = 4e-05
Identities = 83/295 (28%), Positives = 109/295 (36%), Gaps = 41/295 (13%)
Query: 141 GGGAGGAGGGAAGDKDTKSGPLKLSDIG--VEDKSSFKPYSKPGSDKKEPGGGGGG---- 194
G G G G AG + + + V +++ K +K PG G GG
Sbjct: 343 GAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY 402
Query: 195 ---GGGGGGGGGGVSSEKSGFRVPSATCQPFT---PRTG-SPSSSASACSPG---GMLSS 244
GG G G GV VP P P G SP + A+A + G++
Sbjct: 403 GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPG 462
Query: 245 AGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG-RISCGGGINVDVNQHPDGGPG 303
G AP G G G A G GLA G ++ G G+ V P GPG
Sbjct: 463 VGVAP------------GVGVAPGVGVAPG--VGLAPGVGVAPGVGVAPGVGVAPGIGPG 508
Query: 304 GKALGSDCGGSSGSSSGSGPSAPTSSSV--LGSGLVAP---VSPYKPGQTVFPLPPAGMT 358
G A + + + +A + + LG G+ P V PG V P
Sbjct: 509 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 568
Query: 359 YPGSLAGA----YAGYPPQFLPHGVALDPTK-PGSLVGAQLAAAAAGSLGCSKPA 408
PG+LA A Y P L AL PG +VGA AAAAA + +K A
Sbjct: 569 VPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 623
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 60.1 bits (144), Expect = 6e-09
Identities = 56/182 (30%), Positives = 65/182 (35%), Gaps = 51/182 (28%)
Query: 142 GGAGGA--GGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGG 199
GG+GG+ GGG+ G SG S+ GS GG G GGG GG
Sbjct: 491 GGSGGSYGGGGSGGGYGGGSG------------------SRGGSGGSYGGGSGSGGGSGG 532
Query: 200 GGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTD 259
G GGG SG S S G + GG+ G
Sbjct: 533 GYGGGSGGGHSG-------------------GSGGGHSGGSGGNYGGGSGSG-------- 565
Query: 260 VGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSS 319
GG G G GG S G +G +HG G G + GG G GG SG SS
Sbjct: 566 -GGSGGGYGGGSGSRGGSGGSHGG---GSGFGGESGGSYGGGEEASGSGGGYGGGSGKSS 621
Query: 320 GS 321
S
Sbjct: 622 HS 623
Score = 59.3 bits (142), Expect = 1e-08
Identities = 59/187 (31%), Positives = 67/187 (35%), Gaps = 30/187 (16%)
Query: 149 GGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSE 208
GG + + +G + L G S+ S+ GS GGG GGG GGG G G S
Sbjct: 460 GGQEDFESSGAGKIGLGGRGGSG-GSYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGG 518
Query: 209 KSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTG 268
G GS S S GG S GG G GG G G
Sbjct: 519 SYG--------------GGSGSGGGSGGGYGG--GSGGGHSGGSGGGHS---GGSGGNYG 559
Query: 269 GASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTS 328
G S GG +G +G S G G G GS GG SG S G G A S
Sbjct: 560 GGSGSGGGSGGGYGGGSGSRG----------GSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Query: 329 SSVLGSG 335
G G
Sbjct: 610 GGGYGGG 616
Score = 52.0 bits (123), Expect = 2e-06
Identities = 47/138 (34%), Positives = 54/138 (39%), Gaps = 17/138 (12%)
Query: 192 GGGGGGGGGGGGGVSSEKSGFRVP--SATCQPFTPRTGSPSSSASACSPGGMLS---SAG 246
GGGGGGG G GG + S S F F+ +G S+ C GG S S G
Sbjct: 15 GGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYG 74
Query: 247 GAPEG--KDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGG 304
G G GGG +G GGAS G + G GGG GG G
Sbjct: 75 GGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGG-GFGGG---------SGGGFG 124
Query: 305 KALGSDCGGSSGSSSGSG 322
GS GG G G+G
Sbjct: 125 GGYGSGFGGFGGFGGGAG 142
Score = 48.9 bits (115), Expect = 1e-05
Identities = 53/157 (33%), Positives = 55/157 (35%), Gaps = 23/157 (14%)
Query: 135 SSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGG 194
SS S GG GG GG +G S S G F S G G GGG
Sbjct: 8 SSYLSRSGGGGG-GGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 195 G------GGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGA 248
G GGG GGG SS GF G S S GG SS+GG
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGGF--------------GGGSRGFGGASGGG-YSSSGGF 111
Query: 249 PEGKDDKKDTDVGGG-GKGTGGASAEGGPTGLAHGRI 284
G GGG G G GG GG G G I
Sbjct: 112 GGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGI 148
Score = 45.1 bits (105), Expect = 2e-04
Identities = 38/133 (28%), Positives = 47/133 (35%), Gaps = 37/133 (27%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
S GG GG GGG+ G SG G GGG G GGG
Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGG-----------------GHSGGSGGNYGGGSGSGGGS 568
Query: 199 GGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDT 258
GGG GG S + G S S G +GG+ G ++ +
Sbjct: 569 GGGYGGGSGSRGG-------------------SGGSHGGGSGFGGESGGSYGGGEEASGS 609
Query: 259 DVGGGGKGTGGAS 271
GG G G+G +S
Sbjct: 610 G-GGYGGGSGKSS 621
Score = 38.5 bits (88), Expect = 0.019
Identities = 30/83 (36%), Positives = 35/83 (42%), Gaps = 19/83 (22%)
Query: 261 GGGGKGTGGA--------SAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCG 312
GGGG G+GG+ S+ GG G GR S G GG + G G
Sbjct: 18 GGGGLGSGGSIRSSYSRFSSSGGGGG--GGRFSSSSGY---------GGGSSRVCGRGGG 66
Query: 313 GSSGSSSGSGPSAPTSSSVLGSG 335
GS G S G G S+S LG G
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGG 89
Score = 37.7 bits (86), Expect = 0.033
Identities = 31/89 (34%), Positives = 36/89 (40%), Gaps = 9/89 (10%)
Query: 133 KLSSVASNGGGA----GGAGGGAAGDK--DTKSGPLKLSDIGVE---DKSSFKPYSKPGS 183
+ SS + GGG+ G GGG+ G G S +G F S G
Sbjct: 46 RFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGY 105
Query: 184 DKKEPGGGGGGGGGGGGGGGGVSSEKSGF 212
GGG GGG GGG GGG S GF
Sbjct: 106 SSSGGFGGGFGGGSGGGFGGGYGSGFGGF 134
Score = 37.0 bits (84), Expect = 0.057
Identities = 31/80 (38%), Positives = 37/80 (46%), Gaps = 11/80 (13%)
Query: 136 SVASNGGGAGGAG---GGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGG 192
S +S GGG GG GGA+G + SG G F G GG G
Sbjct: 82 SASSLGGGFGGGSRGFGGASGGGYSSSGGFG-GGFGGGSGGGFG-----GGYGSGFGGFG 135
Query: 193 GGGGGGGGGGGGV--SSEKS 210
G GGG GGG GG+ ++EKS
Sbjct: 136 GFGGGAGGGDGGILTANEKS 155
Score = 35.8 bits (81), Expect = 0.13
Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 7/63 (11%)
Query: 138 ASNGGGAGGAGGGAAGDKDTKSGPL-KLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGG 196
+ +GGG+GG GG +G + G S G E S+ G ++ G GGG GG
Sbjct: 562 SGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSY------GGGEEASGSGGGYGG 615
Query: 197 GGG 199
G G
Sbjct: 616 GSG 618
Score = 33.1 bits (74), Expect = 0.82
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
SGGG GGG GGG+ + G SG G+ GS
Sbjct: 526 SGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS 562
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/36 (47%), Positives = 18/36 (50%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
SGGG GGG GGG SG S G G S +G
Sbjct: 530 SGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSG 565
Score = 32.0 bits (71), Expect = 1.8
Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 2/41 (4%)
Query: 15 HSGGGGGG--GGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
HSGG GGG GG GG + + G+ G G GS G +
Sbjct: 542 HSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582
Score = 31.6 bits (70), Expect = 2.4
Identities = 18/41 (43%), Positives = 23/41 (56%), Gaps = 2/41 (4%)
Query: 13 SKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPG--SSPAG 51
S+ GGGGGG G GG+ + S S + G G G SS +G
Sbjct: 12 SRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSG 52
Score = 30.8 bits (68), Expect = 4.1
Identities = 17/34 (50%), Positives = 19/34 (55%), Gaps = 1/34 (2%)
Query: 15 HSGGGGGGGGGGGADPAWTSALS-GNSSGPGPGS 47
+ GGG GGG GGG+ S S G SG G GS
Sbjct: 497 YGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGS 530
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/41 (39%), Positives = 18/41 (43%)
Query: 11 RSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
R S+ GG GGGG G S G S G G S +G
Sbjct: 487 RGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSG 527
Score = 30.0 bits (66), Expect = 6.9
Identities = 14/38 (36%), Positives = 18/38 (47%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
SGG GGGG GG + + G+ G GS G +
Sbjct: 493 SGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGS 530
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/39 (41%), Positives = 18/39 (46%), Gaps = 2/39 (5%)
Query: 16 SGG--GGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
SGG GGG G GGG+ + G SG G GS
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGS 554
Score = 29.6 bits (65), Expect = 9.0
Identities = 16/40 (40%), Positives = 17/40 (42%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
S + GGG G GGG G S G S G G S G
Sbjct: 554 SGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFG 593
Score = 29.6 bits (65), Expect = 9.0
Identities = 13/39 (33%), Positives = 18/39 (46%)
Query: 15 HSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
+ GG G GGG GG + + G+ G GS G +
Sbjct: 558 YGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGES 596
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 60.1 bits (144), Expect = 6e-09
Identities = 54/151 (35%), Positives = 65/151 (43%), Gaps = 19/151 (12%)
Query: 173 SSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQ---PFTPRTGSP 229
SS K YS S GGGGGGGG GGGGGVSS R+ S+ F+ S
Sbjct: 6 SSSKHYSSSRS-------GGGGGGGGCGGGGGVSS----LRISSSKGSLGGGFSSGGFSG 54
Query: 230 SSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGG 289
S + S GG + G G GG +G+ G+S+ GG G + G S GGG
Sbjct: 55 GSFSRGSSGGGCFGGSSGGYGGLGGFG----GGSFRGSYGSSSFGGSYGGSFGGGSFGGG 110
Query: 290 INVDVNQHPDGGPGGKALGSDCGGSSGSSSG 320
+ GG GG G GG G G
Sbjct: 111 -SFGGGSFGGGGFGGGGFGGGFGGGFGGDGG 140
Score = 59.3 bits (142), Expect = 1e-08
Identities = 56/183 (30%), Positives = 69/183 (37%), Gaps = 40/183 (21%)
Query: 163 KLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPF 222
+L DI + ++ + Y + GGGG GGG GGG GG
Sbjct: 434 QLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGG------------------ 475
Query: 223 TPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG 282
SS S GG GG+ G + G G G GG S+ GG G + G
Sbjct: 476 -------GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSG 528
Query: 283 RISCGGGINVDVNQHPDGGPGGKALGSDCGGSS------GSSSGSGPSAPTSSSVLGSGL 336
GGG + GG GG GS GGSS G SS G + +S SV S
Sbjct: 529 --GYGGGSS-------GGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSS 579
Query: 337 VAP 339
P
Sbjct: 580 KGP 582
Score = 53.1 bits (126), Expect = 8e-07
Identities = 54/158 (34%), Positives = 58/158 (36%), Gaps = 23/158 (14%)
Query: 129 SPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFK--PYSKPGSDKK 186
S S SS S GGG GG GG G + K S G F +S+ S
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGG 65
Query: 187 EPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGML--SS 244
GG GG GG GG GGG FR GS SS+ S GG S
Sbjct: 66 CFGGSSGGYGGLGGFGGG------SFR-------------GSYGSSSFGGSYGGSFGGGS 106
Query: 245 AGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG 282
GG G GGGG G G GG GL G
Sbjct: 107 FGGGSFGGGSFGGGGFGGGGFGGGFGGGFGGDGGLLSG 144
Score = 48.5 bits (114), Expect = 2e-05
Identities = 56/194 (28%), Positives = 60/194 (30%), Gaps = 64/194 (32%)
Query: 132 SKLSSVASNGGGAGGAG--GGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPG 189
S L S+GGG G G GG G + G G SS Y S G
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
Query: 190 GGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAP 249
GG GGG GG GG SS+GG
Sbjct: 511 GGYGGGSSSGGHGG---------------------------------------SSSGGYG 531
Query: 250 EGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGS 309
G GGGG G GG S+ GG S GGG GG S
Sbjct: 532 GGSS-------GGGGGGYGGGSSGGGS--------SSGGGYG--------GGSSSGGHKS 568
Query: 310 DCGGSSGSSSGSGP 323
GS G SS GP
Sbjct: 569 SSSGSVGESSSKGP 582
Score = 38.1 bits (87), Expect = 0.025
Identities = 22/51 (43%), Positives = 25/51 (49%)
Query: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
MS S S SS SGGGGGGGG GG + +S + G G S G
Sbjct: 1 MSVRYSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGG 51
Score = 33.9 bits (76), Expect = 0.48
Identities = 18/40 (45%), Positives = 20/40 (50%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
SS GGG GGGGGG + S + G G GSS G
Sbjct: 526 SSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGG 565
Score = 33.5 bits (75), Expect = 0.62
Identities = 19/40 (47%), Positives = 23/40 (57%), Gaps = 3/40 (7%)
Query: 16 SGGGGGGGGGGGADPAWTSA---LSGNSSGPGPGSSPAGS 52
S GGGGGG GGG+ +S+ G SS G SS +GS
Sbjct: 534 SSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGS 573
Score = 32.7 bits (73), Expect = 1.1
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 1/46 (2%)
Query: 8 SALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
S L SGGGG GGG G S+ G SSG G G GS+
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSS-GGGSSGGGHGGGHGGSS 495
Score = 32.0 bits (71), Expect = 1.8
Identities = 19/43 (44%), Positives = 22/43 (51%), Gaps = 1/43 (2%)
Query: 13 SKHSGGGGGGGGGGGADPAWTSALSGNSSGPG-PGSSPAGSTK 54
S G GGG GGGG S+ G+SSG G G S +G K
Sbjct: 525 SSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHK 567
Score = 31.6 bits (70), Expect = 2.4
Identities = 18/39 (46%), Positives = 20/39 (51%), Gaps = 3/39 (7%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSS---GPGPGSSPAG 51
SGGG GGG GG + + SG S G G GSS G
Sbjct: 483 SGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGG 521
Score = 30.8 bits (68), Expect = 4.1
Identities = 18/51 (35%), Positives = 24/51 (47%)
Query: 2 STAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
S++ S+ RS GGGG GGGGG + +S+ G G GS
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGS 56
Score = 30.8 bits (68), Expect = 4.1
Identities = 27/81 (33%), Positives = 32/81 (39%), Gaps = 8/81 (9%)
Query: 262 GGGKGTGGASAEGGPTGL--AHGRISCGGGIN---VDVNQHPDGGPGGKALGSDCGGSSG 316
GGG G GG GG + L + + S GGG + G GG G GG G
Sbjct: 17 GGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGG 76
Query: 317 ---SSSGSGPSAPTSSSVLGS 334
GS + SSS GS
Sbjct: 77 LGGFGGGSFRGSYGSSSFGGS 97
Score = 30.8 bits (68), Expect = 4.1
Identities = 15/35 (42%), Positives = 17/35 (48%)
Query: 17 GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
GG GGG GGG+ G SSG G G +G
Sbjct: 471 GGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSG 505
Score = 30.8 bits (68), Expect = 4.1
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 16 SGGG-GGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
SGGG GGG GG + + G SSG G G GS+
Sbjct: 509 SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSS 547
Score = 30.0 bits (66), Expect = 6.9
Identities = 16/36 (44%), Positives = 18/36 (50%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
S GGG GGG G + G+SSG GSS G
Sbjct: 494 SSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGG 529
Score = 30.0 bits (66), Expect = 6.9
Identities = 14/30 (46%), Positives = 16/30 (53%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGP 45
SGGG GGG G + +S G SS GP
Sbjct: 553 SGGGYGGGSSSGGHKSSSSGSVGESSSKGP 582
>gi|126352608 elastin isoform e precursor [Homo sapiens]
Length = 705
Score = 59.3 bits (142), Expect = 1e-08
Identities = 117/424 (27%), Positives = 145/424 (34%), Gaps = 78/424 (18%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGA--AGDKDTKSGPLKLSDIGV-EDKSSFKPYSK 180
G P P V G G G GGGA G K K P L+ G+ +F +
Sbjct: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87
Query: 181 PGSDKKEPGG-------------GGGGGGGGGGGGGGVSSEKSGFRVPSATCQP-FTPRT 226
PG+ PGG G G GG G GG GVS+ + P A +P P
Sbjct: 88 PGA--LVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSA-GAVVPQPGAGVKPGKVPGV 144
Query: 227 GSPSSSASACSPGGMLSSAG---GAPEGKDDK-KDTDVGGGGKGTGGASAEGGP-TGLAH 281
G P PG G G P G K K VGG G G GGP G+
Sbjct: 145 GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPL 204
Query: 282 G------RISCGGGINVDVNQHPDG-GPGGKALGSDCGGSSGSSSGSG-------PSAPT 327
G ++ G G+ + P G GPGG A G +G +G+G +A
Sbjct: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGTGVGPQAAAAAAAK 261
Query: 328 SSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPG 387
+++ G+G A V P G V P P + G +AG G P A K G
Sbjct: 262 AAAKFGAG-AAGVLPGVGGAGV-PGVPGAIPGIGGIAG--VGTPAAAAAAAAAAKAAKYG 317
Query: 388 SLVGAQLAAAAAGSLGCSKPAGSSP---LAGASPPSVMTASLCRDPYCLSYHCASHLAGA 444
+ G G P P + GA P V A +
Sbjct: 318 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI-----------------P 360
Query: 445 AAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATP---------PSL 495
AA AAA AA K+ Y P GV T AG P P +
Sbjct: 361 GAAVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 417
Query: 496 AGHP 499
AG P
Sbjct: 418 AGVP 421
Score = 47.4 bits (111), Expect = 4e-05
Identities = 83/295 (28%), Positives = 109/295 (36%), Gaps = 41/295 (13%)
Query: 141 GGGAGGAGGGAAGDKDTKSGPLKLSDIG--VEDKSSFKPYSKPGSDKKEPGGGGGG---- 194
G G G G AG + + + V +++ K +K PG G GG
Sbjct: 338 GAGVPGVGVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTY 397
Query: 195 ---GGGGGGGGGGVSSEKSGFRVPSATCQPFT---PRTG-SPSSSASACSPG---GMLSS 244
GG G G GV VP P P G SP + A+A + G++
Sbjct: 398 GVGAGGFPGFGVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGLVPG 457
Query: 245 AGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG-RISCGGGINVDVNQHPDGGPG 303
G AP G G G A G GLA G ++ G G+ V P GPG
Sbjct: 458 VGVAP------------GVGVAPGVGVAPG--VGLAPGVGVAPGVGVAPGVGVAPGIGPG 503
Query: 304 GKALGSDCGGSSGSSSGSGPSAPTSSSV--LGSGLVAP---VSPYKPGQTVFPLPPAGMT 358
G A + + + +A + + LG G+ P V PG V P
Sbjct: 504 GVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFGA 563
Query: 359 YPGSLAGA----YAGYPPQFLPHGVALDPTK-PGSLVGAQLAAAAAGSLGCSKPA 408
PG+LA A Y P L AL PG +VGA AAAAA + +K A
Sbjct: 564 VPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 618
>gi|126352440 elastin isoform a precursor [Homo sapiens]
Length = 724
Score = 59.3 bits (142), Expect = 1e-08
Identities = 117/424 (27%), Positives = 145/424 (34%), Gaps = 78/424 (18%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGA--AGDKDTKSGPLKLSDIGV-EDKSSFKPYSK 180
G P P V G G G GGGA G K K P L+ G+ +F +
Sbjct: 28 GVPGAIPGGVPGGVFYPGAGLGALGGGALGPGGKPLKPVPGGLAGAGLGAGLGAFPAVTF 87
Query: 181 PGSDKKEPGG-------------GGGGGGGGGGGGGGVSSEKSGFRVPSATCQP-FTPRT 226
PG+ PGG G G GG G GG GVS+ + P A +P P
Sbjct: 88 PGA--LVPGGVADAAAAYKAAKAGAGLGGVPGVGGLGVSA-GAVVPQPGAGVKPGKVPGV 144
Query: 227 GSPSSSASACSPGGMLSSAG---GAPEGKDDK-KDTDVGGGGKGTGGASAEGGP-TGLAH 281
G P PG G G P G K K VGG G G GGP G+
Sbjct: 145 GLPGVYPGGVLPGARFPGVGVLPGVPTGAGVKPKAPGVGGAFAGIPGVGPFGGPQPGVPL 204
Query: 282 G------RISCGGGINVDVNQHPDG-GPGGKALGSDCGGSSGSSSGSG-------PSAPT 327
G ++ G G+ + P G GPGG A G +G +G+G +A
Sbjct: 205 GYPIKAPKLPGGYGLPYTTGKLPYGYGPGGVA---GAAGKAGYPTGTGVGPQAAAAAAAK 261
Query: 328 SSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPG 387
+++ G+G A V P G V P P + G +AG G P A K G
Sbjct: 262 AAAKFGAG-AAGVLPGVGGAGV-PGVPGAIPGIGGIAG--VGTPAAAAAAAAAAKAAKYG 317
Query: 388 SLVGAQLAAAAAGSLGCSKPAGSSP---LAGASPPSVMTASLCRDPYCLSYHCASHLAGA 444
+ G G P P + GA P V A +
Sbjct: 318 AAAGLVPGGPGFGPGVVGVPGAGVPGVGVPGAGIPVVPGAGI-----------------P 360
Query: 445 AAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATP---------PSL 495
AA AAA AA K+ Y P GV T AG P P +
Sbjct: 361 GAAVPGVVSPEAAAKAAAKAA---KYGARPGVGVGGIPTYGVGAGGFPGFGVGVGGIPGV 417
Query: 496 AGHP 499
AG P
Sbjct: 418 AGVP 421
Score = 50.1 bits (118), Expect = 6e-06
Identities = 79/296 (26%), Positives = 108/296 (36%), Gaps = 35/296 (11%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGS 183
G P ++K ++ A+ G G G G +G +GV PG
Sbjct: 366 GVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVGAGGFPGFGVGVG--------GIPGV 417
Query: 184 DKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLS 243
G GG G GG G G+S E A + + +A+ + G++
Sbjct: 418 AGVP--GVGGVPGVGGVPGVGISPEAQAAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVP 475
Query: 244 SAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG-RISCGGGINVDVNQHPDGGP 302
G AP G G G A G GLA G ++ G G+ V P GP
Sbjct: 476 GVGVAP------------GVGVAPGVGVAPG--VGLAPGVGVAPGVGVAPGVGVAPGIGP 521
Query: 303 GGKALGSDCGGSSGSSSGSGPSAPTSSSV--LGSGLVAP---VSPYKPGQTVFPLPPAGM 357
GG A + + + +A + + LG G+ P V PG V P
Sbjct: 522 GGVAAAAKSAAKVAAKAQLRAAAGLGAGIPGLGVGVGVPGLGVGAGVPGLGVGAGVPGFG 581
Query: 358 TYPGSLAGA----YAGYPPQFLPHGVALDPTK-PGSLVGAQLAAAAAGSLGCSKPA 408
PG+LA A Y P L AL PG +VGA AAAAA + +K A
Sbjct: 582 AVPGALAAAKAAKYGAAVPGVLGGLGALGGVGIPGGVVGAGPAAAAAAAKAAAKAA 637
Score = 40.8 bits (94), Expect = 0.004
Identities = 83/370 (22%), Positives = 116/370 (31%), Gaps = 61/370 (16%)
Query: 135 SSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKP--YSKPGSDKKEPGGGG 192
+ V G GGA G G GP +G K+ P Y P + K P G G
Sbjct: 173 AGVKPKAPGVGGAFAGIPG-VGPFGGPQPGVPLGYPIKAPKLPGGYGLPYTTGKLPYGYG 231
Query: 193 GGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGK 252
GG G G K+G+ + + +++ G+L GGA
Sbjct: 232 PGGVAGAAG-------KAGYPTGTGVGPQAAAAAAAKAAAKFGAGAAGVLPGVGGAGVPG 284
Query: 253 DDKKDTDVGG-GGKGT------GGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGK 305
+GG G GT A+A+ G A G + G G V P G G
Sbjct: 285 VPGAIPGIGGIAGVGTPAAAAAAAAAAKAAKYGAAAGLVPGGPGFGPGVVGVPGAGVPGV 344
Query: 306 AL---GSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGS 362
+ G +G + P + + + A +PG V +P G+
Sbjct: 345 GVPGAGIPVVPGAGIPGAAVPGVVSPEAAAKAAAKAAKYGARPGVGVGGIPTYGVG---- 400
Query: 363 LAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVM 422
AG + G+ G VG A +G G P G SP +
Sbjct: 401 -AGGFPGF----------------GVGVGGIPGVAGVPGVGGVPGVGGVPGVGISPEAQ- 442
Query: 423 TASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSL 482
A AAA +A AAAAA + + P GV +
Sbjct: 443 -------------------AAAAAKAAKYGVGTPAAAAAKAAAKAAQFGLVPGVGVAPGV 483
Query: 483 TAAAAAGATP 492
A G P
Sbjct: 484 GVAPGVGVAP 493
>gi|154146231 DMRT-like family A2 [Homo sapiens]
Length = 542
Score = 59.3 bits (142), Expect = 1e-08
Identities = 96/366 (26%), Positives = 117/366 (31%), Gaps = 52/366 (14%)
Query: 178 YSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFT----PRTGSP-SSS 232
Y GS GGG G G G GGG + S ++ P T R GSP
Sbjct: 154 YEVFGSVCAADGGGPGAGAPAGTGGGAAGAGGSEAKLQKFDLFPKTLLQAGRPGSPLPPP 213
Query: 233 ASACSPGGMLSSAG-GAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRI--SCGGG 289
SP G S G +PE + G G + G S G P A SC G
Sbjct: 214 VKPLSPDGADSGPGTSSPEVRP-------GSGSENGDGESFSGSPLARASKEAGGSCPGS 266
Query: 290 INVDVNQHPDGGPGGKALGSDCGGSS-----------GSSSGSGPSAPTSSSVLGS---- 334
D LGS+ G + G GSGP T +L
Sbjct: 267 AGPGGGGEEDSPGSASPLGSESGSEADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPG 326
Query: 335 ---GLVAPVSPYKPGQTVFPLPPAGMTYPGSLA-GAYAGYPPQFLPHGVAL--DPTKPGS 388
G++ V G V + + G LA G PP G A D P
Sbjct: 327 HRRGVLELVLQGCGGDVVQAIEQVLNHHRGGLAAGLGPAAPPDKAAVGAAAAADDAWPSR 386
Query: 389 LVGAQLAAAAAGSLGCSKPAGSSP---------LAGASPPSVMTASLCRDPYCLSYHCAS 439
+ A AAAAAG G P + P LAGA P + + R + AS
Sbjct: 387 VDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGAMAPGALGSLSSRSAFSPLQPNAS 446
Query: 440 HLAGAAAASASCAHDPAAAAAALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHP 499
H A A P A L S L Y H + A + P+L P
Sbjct: 447 HFGADAGAY------PLGAPLGL-SPLRLAYSAAAAHSRGLAFMAPYSTAGLVPTLGFRP 499
Query: 500 LYPYGF 505
Y F
Sbjct: 500 PMDYAF 505
Score = 53.5 bits (127), Expect = 6e-07
Identities = 104/392 (26%), Positives = 131/392 (33%), Gaps = 69/392 (17%)
Query: 138 ASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGG-- 195
A GGGA GAGG A + P L G S P KP S G G
Sbjct: 174 AGTGGGAAGAGGSEAKLQKFDLFPKTLLQAG-RPGSPLPPPVKPLSPDGADSGPGTSSPE 232
Query: 196 ---GGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGK 252
G G G G S S S P + P SPG +S G+ G
Sbjct: 233 VRPGSGSENGDGESFSGSPLARASKEAGGSCPGSAGPGGGGEEDSPGS--ASPLGSESGS 290
Query: 253 DDKKDTDVGGGGKGTGGASAEGGPTGL--------AHGR-------ISCGGGINVDVNQH 297
+ K+ G GG S T L H R CGG + + Q
Sbjct: 291 EADKEEGEAAPAPGLGGGSGPRQRTPLDILTRVFPGHRRGVLELVLQGCGGDVVQAIEQV 350
Query: 298 PDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGM 357
+ GG A +G GP+AP + +G+ A +P
Sbjct: 351 LNHHRGGLA------------AGLGPAAPPDKAAVGAAAAA--------DDAWP----SR 386
Query: 358 TYPGSLAGAYAGYP--PQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPL-- 413
+ A A AG P P L G A P L GA +A A GSL S + SPL
Sbjct: 387 VDAAAAAAAAAGGPGLPAPLQAGPAAPPHHRPLLAGA-MAPGALGSL--SSRSAFSPLQP 443
Query: 414 --------AGASPPSVMTASLCRDPYCLSYHCASHLAGAAAASASCAHDPAAAAAALKSG 465
AGA P + A L P L+Y A+ A + + + A L
Sbjct: 444 NASHFGADAGAYP---LGAPLGLSPLRLAYSAAA--AHSRGLAFMAPYSTAGLVPTLGFR 498
Query: 466 YPLVYPTHPLHGVHSSLTAAAAAGATPPSLAG 497
P+ Y L + AAAAA P+ G
Sbjct: 499 PPMDYAFSDL--MRDRSAAAAAAVHKEPTYGG 528
>gi|48762934 alpha 2 type I collagen [Homo sapiens]
Length = 1366
Score = 58.9 bits (141), Expect = 1e-08
Identities = 117/444 (26%), Positives = 141/444 (31%), Gaps = 65/444 (14%)
Query: 13 SKHSGGGGGGGGGGGADPAWTSALSGNSSGPG-------------PGS----SPAGSTKP 55
S G G G G A P L G+ G PGS PAG P
Sbjct: 375 SGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGP 434
Query: 56 FVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPST-PVSPIELDAKKSPLA 114
A P +P R G P + P PV +D + P+
Sbjct: 435 NGDAGRPGEPGLMGPR-------------GLPGSPGNIGPAGKEGPVGLPGIDGRPGPIG 481
Query: 115 LLAQTCSQIGKPDPSPSSKLSSVASNG--GGAGGAGG-GAAGDKDTKSGPLKLSDIGVED 171
P P NG G AG AG GA G GV+
Sbjct: 482 PAGARGEPGNIGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQGVQG 541
Query: 172 KSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPR--TGSP 229
+ P + PG G G G G G+ E F +P P PR G P
Sbjct: 542 GKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGE---FGLPG----PAGPRGERGPP 594
Query: 230 SSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGG 289
S +A G + S P G D K G GT G S GP+GL R G
Sbjct: 595 GESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPS---GPSGLPGER----GA 647
Query: 290 INVDVNQHPDGGPG-----GKALGSDCGGSSGSSSGSGPSAPTS--SSVLGSGLVAPVSP 342
+ + G PG G G+ G+ GP+ T +G P P
Sbjct: 648 AGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707
Query: 343 Y-KPGQ--TVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAA 399
PG+ V P P G P AGA AG P G A P +VG AA
Sbjct: 708 RGSPGERGEVGPAGPNGFAGP---AGA-AGQPGAKGERG-AKGPKGENGVVGPTGPVGAA 762
Query: 400 GSLGCSKPAGSSPLAGASPPSVMT 423
G G + P G + G P MT
Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMT 786
Score = 52.4 bits (124), Expect = 1e-06
Identities = 80/328 (24%), Positives = 110/328 (33%), Gaps = 44/328 (13%)
Query: 122 QIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKP 181
++G P P+ + G AG G +AG P +IG + + P
Sbjct: 224 RVGAPGPAGARGSDGSVGPVGPAGPIG--SAGPPGFPGAPGPKGEIGAVGNAGPAGPAGP 281
Query: 182 GSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTP---RTGSPSSSASACSP 238
+ PG G G G G G++ K +P P P P +A A
Sbjct: 282 RGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGA 341
Query: 239 GGMLSSAGGA-PEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGG-----GINV 292
G++ G A +G+ K G +G G S E G G +G G G+
Sbjct: 342 RGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRG-PNGEAGSAGPPGPPGLRG 400
Query: 293 DVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGS--GLVAPVS-PYKPGQTV 349
G G+A GS G+S +G P + GL+ P P PG
Sbjct: 401 SPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGN-- 458
Query: 350 FPLPPAGMTYPGSLAG-----------------AYAGYPPQFLPHGVALDPTKPG----- 387
+ PAG P L G G+P P G DP K G
Sbjct: 459 --IGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPG---PKGPTGDPGKNGDKGHA 513
Query: 388 SLVGAQLAAAAAGSLGCSKPAGSSPLAG 415
L GA+ A G+ G P G + G
Sbjct: 514 GLAGARGAPGPDGNNGAQGPPGPQGVQG 541
Score = 47.4 bits (111), Expect = 4e-05
Identities = 80/325 (24%), Positives = 108/325 (33%), Gaps = 33/325 (10%)
Query: 123 IGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPG 182
+G P P+ ++ A G AG AG + + + GP + ++ +P +K
Sbjct: 681 VGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGE 740
Query: 183 SDKKEPGGG----------GGGGGGGGGGGGGVSSEKSGFRVPSATCQP-FTPRTGSPSS 231
K P G G G G G G + + P T P RTG P
Sbjct: 741 RGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGP 800
Query: 232 SASACSPG--GMLSSAG-GAPEGKDDK--KDTDVG-------GGGKGTGGASAEGGPTGL 279
S + PG G G P G + +VG G KG G + GP G
Sbjct: 801 SGISGPPGPPGPAGKEGLRGPRGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGT 860
Query: 280 --AHGRISCGGGINVDVNQHPDGGPGGKALGSDCG--GSSGSSSGSGPSAPTSSSVLGSG 335
G + G + + ++ G PG + G G +G GP S +
Sbjct: 861 PGPQGLLGAPGILGLPGSRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSPGVNG- 919
Query: 336 LVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLA 395
AP + G PP PG GYP P G A P P VG
Sbjct: 920 --APGEAGRDGNPGNDGPPGRDGQPGH--KGERGYPGNIGPVGAAGAP-GPHGPVGPAGK 974
Query: 396 AAAAGSLGCSKPAGSSPLAGASPPS 420
G G S P G + G PS
Sbjct: 975 HGNRGETGPSGPVGPAGAVGPRGPS 999
Score = 35.0 bits (79), Expect = 0.21
Identities = 69/253 (27%), Positives = 82/253 (32%), Gaps = 53/253 (20%)
Query: 177 PYSKPGSDKKE-----PGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSS 231
P PG D ++ PG G G G GG + G + PR P
Sbjct: 46 PPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR--GPPG 103
Query: 232 SASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGIN 291
+A A P G AG E G G GA GP G A
Sbjct: 104 AAGAPGPQGFQGPAGEPGEP-----------GQTGPAGARGPAGPPGKAG---------- 142
Query: 292 VDVNQHPDGGPGGKALGSDCG--GSSGSSSGSG-PSAPTSSSVLG-SGLVAPVSPYKPGQ 347
DG PG + G G G+ G P P + G +GL G
Sbjct: 143 ------EDGHPGKPGRPGERGVVGPQGARGFPGTPGLPGFKGIRGHNGL--------DGL 188
Query: 348 TVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAGSLGCSKP 407
P P PG A G P Q G+ P + G VGA A A GS G P
Sbjct: 189 KGQPGAPGVKGEPG--APGENGTPGQTGARGL---PGERGR-VGAPGPAGARGSDGSVGP 242
Query: 408 AG-SSPLAGASPP 419
G + P+ A PP
Sbjct: 243 VGPAGPIGSAGPP 255
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 58.9 bits (141), Expect = 1e-08
Identities = 62/196 (31%), Positives = 73/196 (37%), Gaps = 42/196 (21%)
Query: 146 GAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGV 205
G GGG G + SG +S SSF S+ GGGGGG GGGG G
Sbjct: 11 GRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSR---------HGGGGGGFGGGGFGSR 61
Query: 206 SSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGK 265
S G G+ S S S GG +AGG GG G
Sbjct: 62 SLVGLG---------------GTKSISISVAGGGGGFGAAGG------------FGGRGG 94
Query: 266 GTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSA 325
G GG S+ GG +G + G GGG GGPGG GG G G P
Sbjct: 95 GFGGGSSFGGGSGFSGG--GFGGGGFGGGRFGGFGGPGGV---GGLGGPGGFGPGGYPGG 149
Query: 326 PTSSSVLGSGLVAPVS 341
SV L+ P++
Sbjct: 150 IHEVSV-NQSLLQPLN 164
Score = 53.1 bits (126), Expect = 8e-07
Identities = 45/137 (32%), Positives = 51/137 (37%), Gaps = 22/137 (16%)
Query: 192 GGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEG 251
GG GG G GGG SS S + +G S + S GG S GG G
Sbjct: 519 GGSGGRGSSSGGGYSSGSSSYG------------SGGRQSGSRGGSGGGGSISGGGYGSG 566
Query: 252 KDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDC 311
GGG KG S GG G G+ S GGG G G GS
Sbjct: 567 GGSGGRYGSGGGSKG---GSISGGGYGSGGGKHSSGGGSR-------GGSSSGGGYGSGG 616
Query: 312 GGSSGSSSGSGPSAPTS 328
GGSS SG + +S
Sbjct: 617 GGSSSVKGSSGEAFGSS 633
Score = 51.6 bits (122), Expect = 2e-06
Identities = 50/151 (33%), Positives = 61/151 (40%), Gaps = 32/151 (21%)
Query: 135 SSVASNG--GGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGG 192
S+VAS GG+GG G + G + S S GS ++ G G
Sbjct: 510 SNVASKAAFGGSGGRGSSSGGGYSSGS-------------------SSYGSGGRQSGSRG 550
Query: 193 GGGGGGGGGGGGV-SSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEG 251
G GGGG GGG S SG R S G S S GG SS GG+ G
Sbjct: 551 GSGGGGSISGGGYGSGGGSGGRYGSG-----GGSKGGSISGGGYGSGGGKHSSGGGSRGG 605
Query: 252 KDDKKDTDVGGGGKGTGGASAEGGPTGLAHG 282
+ GG G G GG+S+ G +G A G
Sbjct: 606 -----SSSGGGYGSGGGGSSSVKGSSGEAFG 631
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/166 (30%), Positives = 59/166 (35%), Gaps = 45/166 (27%)
Query: 131 SSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGG 190
+S S ++ +GGG GG GGG G + S +G+ S G GG
Sbjct: 37 TSSFSCLSRHGGGGGGFGGGGFGSR---------SLVGLGGTKSISISVAGG------GG 81
Query: 191 GGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPE 250
G G GG GG GGG GS S S GG GG
Sbjct: 82 GFGAAGGFGGRGGGFGG-------------------GSSFGGGSGFSGGGF--GGGGFGG 120
Query: 251 GKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQ 296
G+ GG G GG GGP G G GG V VNQ
Sbjct: 121 GR--------FGGFGGPGGVGGLGGPGGFGPGGYP-GGIHEVSVNQ 157
Score = 40.4 bits (93), Expect = 0.005
Identities = 34/108 (31%), Positives = 42/108 (38%), Gaps = 10/108 (9%)
Query: 230 SSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGG 289
S +A S G SS GG G + G GG+ +G GG ++ G GGG
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGS-----SSYGSGGRQSGSRGGSGGGGSISGGGYGSGGG 568
Query: 290 INVDVNQHPDGG--PGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSG 335
++ GG GG G G G S G S SSS G G
Sbjct: 569 SG---GRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYG 613
Score = 36.2 bits (82), Expect = 0.096
Identities = 29/81 (35%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 136 SVASNGGGAGGAGGGAAGDKD-TKSGPLKLSDIGVED-KSSFKPYSKPGSDKKEPGGGGG 193
S++ G G+GG GG G +K G + G K S S+ GS GGG G
Sbjct: 557 SISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSS---GGGYG 613
Query: 194 GGGGGGGGGGGVSSEKSGFRV 214
GGGG G S E G V
Sbjct: 614 SGGGGSSSVKGSSGEAFGSSV 634
Score = 32.7 bits (73), Expect = 1.1
Identities = 16/35 (45%), Positives = 20/35 (57%)
Query: 19 GGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
GGG G GGG + + G+SSG G GS GS+
Sbjct: 586 GGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSS 620
Score = 32.3 bits (72), Expect = 1.4
Identities = 18/44 (40%), Positives = 24/44 (54%), Gaps = 5/44 (11%)
Query: 13 SKHSGGGGGGGGGGGADPA-----WTSALSGNSSGPGPGSSPAG 51
S+H GGGGG GGGG + T ++S + +G G G AG
Sbjct: 44 SRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGGGGGFGAAG 87
Score = 32.0 bits (71), Expect = 1.8
Identities = 24/62 (38%), Positives = 26/62 (41%), Gaps = 12/62 (19%)
Query: 13 SKHSGGGGGGGG------GGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVPPSDPL 66
S SGGG GGGG GG P L G G GPG P G +H V + L
Sbjct: 106 SGFSGGGFGGGGFGGGRFGGFGGPGGVGGL-GGPGGFGPGGYPGG-----IHEVSVNQSL 159
Query: 67 RQ 68
Q
Sbjct: 160 LQ 161
Score = 31.6 bits (70), Expect = 2.4
Identities = 19/42 (45%), Positives = 22/42 (52%), Gaps = 4/42 (9%)
Query: 16 SGGGGGGGGG----GGADPAWTSALSGNSSGPGPGSSPAGST 53
SGGG G GGG GG +S+ G SG G SS GS+
Sbjct: 585 SGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSS 626
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 58.2 bits (139), Expect = 2e-08
Identities = 78/300 (26%), Positives = 105/300 (35%), Gaps = 71/300 (23%)
Query: 60 VPPSDPLRQANRLPIKVLKMLTARTGHILHPEY---LQPLPSTPVSPIELDAKKSPLALL 116
V PS+P+ + R + + + +R + + L P P+ P P E
Sbjct: 400 VTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEA---------- 449
Query: 117 AQTCSQIGKPDPSPSSKLSS-VASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSF 175
P+ ++LSS V+ +G G G G G +D + +
Sbjct: 450 -----------PNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSG-----------GDY 487
Query: 176 KPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASA 235
P + GS G G G GGG G G G SS SG G+ S
Sbjct: 488 MPMNNWGS-----GNGRGSGGGQGSNGQGSSSHSSG---------------GNQCSGEGQ 527
Query: 236 CSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVN 295
S GG S+ G+ G +D GG G+GG GG HG GGG
Sbjct: 528 GSRGGQGSNGQGSG-GNQCSRDGQGTAGGHGSGGGQRPGG----GHGS---GGG------ 573
Query: 296 QHPDGGPG-GKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPP 354
Q P G G G S G SGS GS S+ ++ K Q P PP
Sbjct: 574 QGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPP 633
Score = 34.7 bits (78), Expect = 0.28
Identities = 24/70 (34%), Positives = 27/70 (38%), Gaps = 4/70 (5%)
Query: 135 SSVASNGGGAGGAGGGAAGDKDTKSGP--LKLSDIG--VEDKSSFKPYSKPGSDKKEPGG 190
S N GG G+G G D D + G K S G + K P P P G
Sbjct: 582 SGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAG 641
Query: 191 GGGGGGGGGG 200
G GG G GG
Sbjct: 642 GTGGKGKSGG 651
Score = 33.9 bits (76), Expect = 0.48
Identities = 21/64 (32%), Positives = 26/64 (40%)
Query: 139 SNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
S GG G+G G+ GD + K S G +S + P P GG GG G
Sbjct: 588 SGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKG 647
Query: 199 GGGG 202
GG
Sbjct: 648 KSGG 651
Score = 30.0 bits (66), Expect = 6.9
Identities = 34/119 (28%), Positives = 42/119 (35%), Gaps = 13/119 (10%)
Query: 139 SNGGGAGGA-----GGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGG 193
SNG G+GG G G AG + G G P GS + GGG
Sbjct: 535 SNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQG--PGDGHGSGGGKNSGGGK 592
Query: 194 GGGGGGGGGG----GVSSEKSGF--RVPSATCQPFTPRTGSPSSSASACSPGGMLSSAG 246
G G G G G G S +K + ++ + Q P P A GG S G
Sbjct: 593 GSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGG 651
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 58.2 bits (139), Expect = 2e-08
Identities = 122/497 (24%), Positives = 161/497 (32%), Gaps = 127/497 (25%)
Query: 96 LPSTPVSPIELDAKKSPLALLAQTCSQIGKPD-------PSPSSKLSSVASNGGGAGGAG 148
+P+ P ++ L L + +G P P P S++ GG G
Sbjct: 692 VPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSAL----GGQPGFP 747
Query: 149 GGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGG---- 204
GAAG + T P+S PG + GGGGG GGGGGGG
Sbjct: 748 FGAAGRQST-------------------PHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQ 788
Query: 205 --------VSSEKSG------FRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAG---- 246
S+ K G F PS+ F G +A + + M++S G
Sbjct: 789 PDFQPSQRTSASKLGALSLGSFNKPSSKDNLF----GQSCLAALSTACQNMIASLGAPNL 844
Query: 247 -------GAPEGKDDKKDTDVGGG------------GKGTGGASAEGGPTGLAHGRISCG 287
PEGK + G G GA GGP+G +
Sbjct: 845 NVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKAS 904
Query: 288 G---------GINVDVN---QHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSG 335
G G ++ N + G G G G SG +P +
Sbjct: 905 GPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSP--GTFFDKY 962
Query: 336 LVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLA 395
AP S PG + +G GS AG G P PH AL T P GA+L
Sbjct: 963 SAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAP---TPHEKAL--TSPSWGKGAELL 1017
Query: 396 AA----AAGSL-GCSKPAGSSPLAGASPPSVMTASLCRD---------PYCLSYHCASHL 441
GSL G +K SSP G ++ S + P L S L
Sbjct: 1018 LGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPL 1077
Query: 442 AGAA-----AASASCAHDPAAAAAALKSGY-------PLVY-----PTHP-LHGVHSSLT 483
+ + H P A AL G P Y P HP G+ T
Sbjct: 1078 VTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRT 1137
Query: 484 AAAAAGATPPSLAGHPL 500
+++GA PP HPL
Sbjct: 1138 PTSSSGAPPPDEI-HPL 1153
Score = 42.4 bits (98), Expect = 0.001
Identities = 112/458 (24%), Positives = 145/458 (31%), Gaps = 105/458 (22%)
Query: 2 STAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGSTKPFVHAVP 61
ST S + S +GGGGG GGGG A+ P
Sbjct: 755 STPHSGPGVNSPPSAGGGGGSSGGGGGGGAY----------------------------P 786
Query: 62 PSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTC- 120
P + + R L L+ G P L +S LA L+ C
Sbjct: 787 PQPDFQPSQRTSASKLGALS--LGSFNKPSSKDNL-----------FGQSCLAALSTACQ 833
Query: 121 ---SQIGKPD----------PSPSSKLSSVASNGGG-AGGAG-----GGAAGDKDTKSGP 161
+ +G P+ P KLS ++G AG G GG A GP
Sbjct: 834 NMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGP 893
Query: 162 LKLSDIGVEDKSSFKPYSKPGSDKKEP--------GGGGGGGGGGGGGGGGVSSEKSGFR 213
S G + P ++ P G G GGGG G G SG
Sbjct: 894 SGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHV 953
Query: 214 VPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKG-TGGASA 272
P F + +P S GG A G G+ VGG G T GA
Sbjct: 954 SPGTF---FDKYSAAPDS-------GG----APGVSPGQQQASGAAVGGSSAGETRGAPT 999
Query: 273 EGGPTGLAHGRISCGGGINVDVNQHPD--GGPGGKALGSDCGGSSG-------SSSGSGP 323
P A S G G + + PD G G A + G S+S +
Sbjct: 1000 ---PHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANE 1056
Query: 324 SAPTSSSVLGSGLV-APVSPYKPGQTVFPLPPAGMTYPGSLAGAYA-GYPPQFLPHGVAL 381
+SSS LV A SP G LPP G+ AG + PP L G+
Sbjct: 1057 DEVSSSSDNPQALVKASRSPLVTGSP--KLPPRGVG-----AGEHGPKAPPPALGLGIMS 1109
Query: 382 DPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPP 419
+ T G G+ G + + +GA PP
Sbjct: 1110 NSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPP 1147
>gi|45439359 triple functional domain (PTPRF interacting) [Homo
sapiens]
Length = 3097
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/214 (28%), Positives = 85/214 (39%), Gaps = 38/214 (17%)
Query: 189 GGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACS---------PG 239
GG GG GGGGG GGGG S SG ++C G+PS+S S S P
Sbjct: 2297 GGSGGSGGGGGSGGGGAPSGGSGHSGGPSSC------GGAPSTSRSRPSRIPQPVRHHPP 2350
Query: 240 GMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPD 299
++SSA + D T G GA+ E GP+ A R G + +
Sbjct: 2351 VLVSSAASSQAEADKMSGTSTPGPSLPPPGAAPEAGPS--APSRRPPGADAE-GSEREAE 2407
Query: 300 GGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSG--------------LVAPVSPYKP 345
P K L S G++ ++SGS P AP + G L +P+S P
Sbjct: 2408 PIPKMKVLESPRKGAA-NASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVP 2466
Query: 346 GQTVFPLPPA-----GMTYPGSLAGAYAGYPPQF 374
P PP+ G ++ S+ + A P F
Sbjct: 2467 SLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSF 2500
Score = 43.9 bits (102), Expect = 5e-04
Identities = 66/263 (25%), Positives = 89/263 (33%), Gaps = 46/263 (17%)
Query: 15 HSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG----STKPFVHAVPPSDPLRQAN 70
HSGGGGGGG GG SG G G G +P+G S P PS + +
Sbjct: 2290 HSGGGGGGGSGG----------SGGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTSRSRPS 2339
Query: 71 RLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSP 130
R+P V HP P S A+ ++ + + P +P
Sbjct: 2340 RIPQPVRH----------HP------PVLVSSAASSQAEADKMSGTSTPGPSLPPPGAAP 2383
Query: 131 SSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGG 190
+ S+ + GA G + K L+ G + S P P D + G
Sbjct: 2384 EAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKGAANASGSSP-DAPAKDARASLG 2442
Query: 191 GGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRT-------------GSPSS-SASAC 236
G G ++S S VPS +PF P + SP+S S
Sbjct: 2443 TLPLGKPRAGAASPLNSPLSS-AVPSLGKEPFPPSSPLQKGGSFWSSIPASPASRPGSFT 2501
Query: 237 SPGGMLSSAGGAPEGKDDKKDTD 259
PG S P KDTD
Sbjct: 2502 FPGDSDSLQRQTPRHAAPGKDTD 2524
Score = 41.2 bits (95), Expect = 0.003
Identities = 46/172 (26%), Positives = 67/172 (38%), Gaps = 3/172 (1%)
Query: 262 GGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGS 321
GGG G+GG A G +G + G SCGG + P P SS +SS +
Sbjct: 2303 GGGGGSGGGGAPSGGSGHSGGPSSCGGAPSTS-RSRPSRIPQPVRHHPPVLVSSAASSQA 2361
Query: 322 GPSAPTSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFL--PHGV 379
+ +S G L P + + G + P G GS A + L P
Sbjct: 2362 EADKMSGTSTPGPSLPPPGAAPEAGPSAPSRRPPGADAEGSEREAEPIPKMKVLESPRKG 2421
Query: 380 ALDPTKPGSLVGAQLAAAAAGSLGCSKPAGSSPLAGASPPSVMTASLCRDPY 431
A + + A+ A A+ G+L KP + SP S SL ++P+
Sbjct: 2422 AANASGSSPDAPAKDARASLGTLPLGKPRAGAASPLNSPLSSAVPSLGKEPF 2473
>gi|4507163 SRY (sex determining region Y)-box 4 [Homo sapiens]
Length = 474
Score = 57.8 bits (138), Expect = 3e-08
Identities = 78/312 (25%), Positives = 107/312 (34%), Gaps = 61/312 (19%)
Query: 163 KLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPF 222
K+ SS SKPG +K + GG GGGG GGGGGGG SS G
Sbjct: 133 KVKSGNANSSSSAAASSKPG-EKGDKVGGSGGGGHGGGGGGG-SSNAGG----------- 179
Query: 223 TPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHG 282
GG +S GGA KK G K GGA GG H
Sbjct: 180 ----------------GGGGASGGGANSKPAQKKSC----GSKVAGGA---GGGVSKPHA 216
Query: 283 RISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSP 342
++ G GG GGKA + + +G+ P ++ L +P
Sbjct: 217 KLILAG-----------GGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSLYKARTP 265
Query: 343 -YKPGQTVFPLPPAGMTYPGS-----------LAGAYAGYPPQFLPHGVALDPTKPGSLV 390
+ A + PG L G G DP+ P L
Sbjct: 266 SASASASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGADPSDPLGLY 325
Query: 391 GAQLAAAA--AGSLGCSKPAGSSPLAGASPPSVMTASLCRDPYCLSYHCASHLAGAAAAS 448
+ A + A SL A SSP AG SP + R SH + +A++
Sbjct: 326 EEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHASSSASSH 385
Query: 449 ASCAHDPAAAAA 460
+S + ++++
Sbjct: 386 SSSSSSSGSSSS 397
Score = 52.0 bits (123), Expect = 2e-06
Identities = 95/387 (24%), Positives = 132/387 (34%), Gaps = 61/387 (15%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPG--------SSPAGSTKPFVHAVPPS 63
+S + G GG DP+W SG+ P P +H S
Sbjct: 31 ASSPTPGSTASTGGKADDPSWCKTPSGHIKRPMNAFMVWSQIERRKIMEQSPDMHNAEIS 90
Query: 64 DPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIELDAKKSPLALLAQTCSQI 123
L + +L K+ R L +++ P P + KS A + + +
Sbjct: 91 KRLGKRWKLLKDSDKIPFIREAERLRLKHMADYPDYKYRPRK--KVKSGNANSSSSAAAS 148
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGS 183
K P K V +GGG G GGG G + G S G ++ KP K
Sbjct: 149 SK----PGEKGDKVGGSGGG-GHGGGGGGGSSNAGGGGGGASGGG----ANSKPAQKKSC 199
Query: 184 DKKEPGGGGGGG---------GGGGGGGGGVSSEKSGFRVPSATCQPFTP---------- 224
K GG GGG GGGGGG ++ + F A P
Sbjct: 200 GSKVAGGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADHHSL 259
Query: 225 -RTGSPSSSASACSPGGMLSSAGGAPEGKD--DKKDTDVGGGGKGTGGASAEGGPTGLAH 281
+ +PS+SASA S +SA A GK +KK V GG P G
Sbjct: 260 YKARTPSASASASSAAS--ASAALAAPGKHLAEKKVKRV----YLFGGLGTSSSPVG--- 310
Query: 282 GRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVS 341
G G D + P G G S + S SG S+ SS G A
Sbjct: 311 -----GVGAGADPSD-----PLGLYEEEGAGCSPDAPSLSGRSSAASSPAAGRS-PADHR 359
Query: 342 PYKPGQTVFPLPPAGMTYPGSLAGAYA 368
Y + P P + ++ S A +++
Sbjct: 360 GYASLRAASPAPSSAPSHASSSASSHS 386
Score = 44.3 bits (103), Expect = 4e-04
Identities = 84/348 (24%), Positives = 122/348 (35%), Gaps = 55/348 (15%)
Query: 222 FTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAH 281
+ PR S +A++ S S+A + G+ K GGGG G GG GG +
Sbjct: 128 YRPRKKVKSGNANSSS-----SAAASSKPGEKGDKVGGSGGGGHGGGGG---GGSSNAGG 179
Query: 282 GRISCGGGINVDVNQHPDGGPGGK-ALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPV 340
G GGG + GG K A CG +G G S P + +L G
Sbjct: 180 G----GGGAS-------GGGANSKPAQKKSCGSKVAGGAGGGVSKPHAKLILAGG----- 223
Query: 341 SPYKPGQTVFPLPPAGMTYPGSLAGAYAGYPPQFLPHGVALDPTKPGSLVGAQLAAAAAG 400
G A ++ AGA A LP G A D SL A+ +A+A
Sbjct: 224 -----GGGGKAAAAAAASFAAEQAGAAA-----LLPLGAAAD---HHSLYKARTPSASAS 270
Query: 401 SLGCSKPAGSSPLAGASPPSVMTASLCRDPYCL-SYHCASHLAGAAAASASCAHDPAAAA 459
+ A S+ A A+P + + Y +S G A A DP+
Sbjct: 271 ----ASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGA----DPSDPL 322
Query: 460 AALKSGYPLVYPTHPLHGVHSSLTAAAAAGATPPSLAGHPLYPYGFMLPNDPLPHICNWV 519
+ P P SS ++ AAG +P G+ P+ H +
Sbjct: 323 GLYEEEGAGCSPDAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPAPSSAPSHASSSA 382
Query: 520 SANGPCDKRFATS------EELLSHLRTHTAFPGTDKLLSGYPSSSSL 561
S++ +S E+ L L + F L + SSS+L
Sbjct: 383 SSHSSSSSSSGSSSSDDEFEDDLLDLNPSSNFESMS--LGSFSSSSAL 428
Score = 39.3 bits (90), Expect = 0.011
Identities = 64/283 (22%), Positives = 93/283 (32%), Gaps = 51/283 (18%)
Query: 2 STAPSLSALRSSKHSGGGGGG-GGGGGADPAWTSALSGNSSGPGPGSSPA---------- 50
+ A S + K G GGGG GGGGG + G +SG G S PA
Sbjct: 145 AAASSKPGEKGDKVGGSGGGGHGGGGGGGSSNAGGGGGGASGGGANSKPAQKKSCGSKVA 204
Query: 51 -----GSTKPFV-----------HAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQ 94
G +KP A + A + L L A H H Y
Sbjct: 205 GGAGGGVSKPHAKLILAGGGGGGKAAAAAAASFAAEQAGAAALLPLGAAADH--HSLYKA 262
Query: 95 PLPSTPVSPIELDAKKSPLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGD 154
PS S + S A LA + + + ++ GG G GA
Sbjct: 263 RTPSASAS---ASSAASASAALAAPGKHLAEKKVKRVYLFGGLGTSSSPVGGVGAGA--- 316
Query: 155 KDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRV 214
S PL L + E+ + P P + G G +S ++
Sbjct: 317 --DPSDPLGLYE---EEGAGCSP-DAPSLSGRSSAASSPAAGRSPADHRGYASLRAASPA 370
Query: 215 PSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKD 257
PS+ +PS ++S+ S SS+ G+ D+ +D
Sbjct: 371 PSS----------APSHASSSASSHSSSSSSSGSSSSDDEFED 403
>gi|49574532 glycogen synthase kinase 3 alpha [Homo sapiens]
Length = 483
Score = 57.4 bits (137), Expect = 4e-08
Identities = 47/146 (32%), Positives = 56/146 (38%), Gaps = 50/146 (34%)
Query: 140 NGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGG 199
+GGG G G G +G T S +++PG GGGGGGG
Sbjct: 2 SGGGPSGGGPGGSGRARTSS------------------FAEPG----------GGGGGGG 33
Query: 200 GGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTD 259
GG GG +S G TG +S A G SS+GG P G
Sbjct: 34 GGPGGSASGPGG--------------TGGGKASVGAMGGGVGASSSGGGPGGS------- 72
Query: 260 VGGGGKGTGGASAEGGPTGLAHGRIS 285
GGGG G GA P G+ GR S
Sbjct: 73 -GGGGSGGPGAGTSFPPPGVKLGRDS 97
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/146 (30%), Positives = 58/146 (39%), Gaps = 23/146 (15%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGS 183
G P S ++ SS A GGG GG GGG G + SGP G S G+
Sbjct: 9 GGPGGSGRARTSSFAEPGGGGGGGGGGPGG---SASGP---GGTGGGKASVGAMGGGVGA 62
Query: 184 DKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLS 243
G GG GGGG GG G G S G ++ G S + +++
Sbjct: 63 SSSGGGPGGSGGGGSGGPGAGTSFPPPGVKL------------GRDSGKVTT-----VVA 105
Query: 244 SAGGAPEGKDDKKDTDVGGGGKGTGG 269
+ G PE + TD+ G G+ G
Sbjct: 106 TLGQGPERSQEVAYTDIKVIGNGSFG 131
Score = 42.4 bits (98), Expect = 0.001
Identities = 45/151 (29%), Positives = 52/151 (34%), Gaps = 52/151 (34%)
Query: 192 GGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEG 251
GGG GGG GG G + ++S PGG GG
Sbjct: 3 GGGPSGGGPGGSG------------------------RARTSSFAEPGG-----GGG--- 30
Query: 252 KDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDC 311
GGGG G AS GG G + GGG+ + GGPGG
Sbjct: 31 ---------GGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSS---GGGPGGS------ 72
Query: 312 GGSSGSSSGSGPSAPTSSSVLG--SGLVAPV 340
GG G+G S P LG SG V V
Sbjct: 73 GGGGSGGPGAGTSFPPPGVKLGRDSGKVTTV 103
Score = 35.8 bits (81), Expect = 0.13
Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 5/41 (12%)
Query: 16 SGGGGGGGGGGGADPAWTSALS-----GNSSGPGPGSSPAG 51
SGGG GGG GG+ A TS+ + G G GPG S +G
Sbjct: 2 SGGGPSGGGPGGSGRARTSSFAEPGGGGGGGGGGPGGSASG 42
Score = 35.8 bits (81), Expect = 0.13
Identities = 22/52 (42%), Positives = 25/52 (48%), Gaps = 15/52 (28%)
Query: 17 GGGGGGGGGG-----------GADPAWTSALSG----NSSGPGPGSSPAGST 53
GGGGGGGGGG G A A+ G +SSG GPG S G +
Sbjct: 26 GGGGGGGGGGPGGSASGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGS 77
Score = 34.7 bits (78), Expect = 0.28
Identities = 28/82 (34%), Positives = 35/82 (42%), Gaps = 15/82 (18%)
Query: 267 TGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGKALGSDCGGSSGSSSGSGPSAP 326
+GG + GGP G R S P GG GG GG GS+SG G +
Sbjct: 2 SGGGPSGGGPGGSGRARTSSFA--------EPGGGGGGGG-----GGPGGSASGPGGTGG 48
Query: 327 TSSSV--LGSGLVAPVSPYKPG 346
+SV +G G+ A S PG
Sbjct: 49 GKASVGAMGGGVGASSSGGGPG 70
Score = 30.0 bits (66), Expect = 6.9
Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 7/47 (14%)
Query: 16 SGGGGGGGG-------GGGADPAWTSALSGNSSGPGPGSSPAGSTKP 55
SG GG GGG GGG + + G S G G G AG++ P
Sbjct: 41 SGPGGTGGGKASVGAMGGGVGASSSGGGPGGSGGGGSGGPGAGTSFP 87
>gi|47778921 alpha 1 type XIX collagen precursor [Homo sapiens]
Length = 1142
Score = 56.6 bits (135), Expect = 7e-08
Identities = 101/395 (25%), Positives = 126/395 (31%), Gaps = 66/395 (16%)
Query: 5 PSLSALRSSKHSGGG-----GGGGGGGGADPAWTS-----ALSGNSSGPGPGSSPAGSTK 54
P ++ K GG G G G A P S L GN PGP
Sbjct: 551 PGKQGIKGEKGDPGGIIGPPGLPGPKGEAGPPGKSLPGEPGLDGNPGAPGPRGPKGERGL 610
Query: 55 PFVHAVPPSDPLRQANRLPIKVLKMLTARTGHILHPEYLQPLPSTPVSPIE-----LDAK 109
P VH P D Q +P + A I P L LP TP +P D K
Sbjct: 611 PGVHG-SPGDIGPQGIGIPGRTGAQGPAGEPGIQGPRGLPGLPGTPGTPGNDGVPGRDGK 669
Query: 110 KS---------PLALLAQTCSQIGKPDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSG 160
L LL + + + + + + SN G GGAG D + G
Sbjct: 670 PGLPGPPGDPIALPLLGDIGALLKNFCGNCQASVPGLKSNKGEEGGAGEPGKYDSMARKG 729
Query: 161 PLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQ 220
DIG P PG PG G G G G G+ EK +
Sbjct: 730 -----DIG--------PRGPPGI----PGREGPKGSKGERGYPGIPGEKGDEGLQGIPGI 772
Query: 221 PFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLA 280
P P P PG M + P G +K +D G G G G P
Sbjct: 773 PGAPGPTGP--------PGLMGRTGHPGPTGAKGEKGSDGPPGKPGPPG--PPGIPFNER 822
Query: 281 HGRIS---CGGGINVDVNQHPDGGPGGKALGSDCG-----------GSSGSSSGSGPSAP 326
+G S GG+NV P G PG K G G G GP+ P
Sbjct: 823 NGMSSLYKIKGGVNVPSYPGPPGPPGPKGDPGPVGEPGAMGLPGLEGFPGVKGDRGPAGP 882
Query: 327 TSSSVLGSGLVAPVSPYKPGQTVFPLPPAGMTYPG 361
+ + AP P PG+ P + +PG
Sbjct: 883 PGIAGMSGKPGAPGPPGVPGEPGERGPVGDIGFPG 917
Score = 35.4 bits (80), Expect = 0.16
Identities = 78/301 (25%), Positives = 100/301 (33%), Gaps = 29/301 (9%)
Query: 140 NGGGAGGAGG-GAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGGGGG 198
N G AG G G+ G K K P + G K K E G G G G
Sbjct: 290 NKGEAGLPGAPGSPGQKGHKGEPGENGLHGAPGFPGQKGEQGFEGSKGETGEKGEQGEKG 349
Query: 199 GGGGGGVSSEKSGFRVPSATCQPFTPR-----TGSPSSSASACSPGGMLSSAGGAPEGKD 253
G++ E +G + P P+ TG P A PG + P GK+
Sbjct: 350 DPALAGLNGE-NGLKGDLGPHGPPGPKGEKGDTGPPGPPAL---PGSLGIQGPQGPPGKE 405
Query: 254 DKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVD---VNQHPDGGPGGKALGSD 310
++ G G G GP G+ + GG N D ++H GG G +
Sbjct: 406 GQRGRRGKTGPPGKPGPPGPPGPPGIQGIHQTLGGYYNKDNKGNDEHEAGGLKGDKGETG 465
Query: 311 CGGSSGSSSGSG----PSAPTSSSVLGS----GLVAPVSPYKPGQTVFPLPPAGMTYPGS 362
G GS G P P + G G++ S G+ P PP + PG
Sbjct: 466 LPGFPGSVGPKGQKGEPGEPFTKGEKGDRGEPGVIG--SQGVKGEPGDPGPPGLIGSPG- 522
Query: 363 LAGAYAGYPPQFLPHGVALDPTKPG--SLVGAQLAAAAAGSLG--CSKPAGSSPLAGASP 418
L G G P G D PG + G Q G G P P A P
Sbjct: 523 LKG-QQGSAGSMGPRGPPGDVGLPGEHGIPGKQGIKGEKGDPGGIIGPPGLPGPKGEAGP 581
Query: 419 P 419
P
Sbjct: 582 P 582
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 56.2 bits (134), Expect = 9e-08
Identities = 65/223 (29%), Positives = 73/223 (32%), Gaps = 78/223 (34%)
Query: 126 PDPSPSSKLSSVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDK 185
P+ S S S +GGG+ G GGG Y GS
Sbjct: 499 PNVSVSVSTSHTTISGGGSRGGGGGG--------------------------YGSGGSSY 532
Query: 186 KEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSA 245
GG G GGGGGGG G S S + S GG S
Sbjct: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYG-----------------------SGGGSYGSG 569
Query: 246 GGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGPGGK 305
GG GGG G S+ GG G + G GGG G GG+
Sbjct: 570 GG-------------GGGHGSYGSGSSSGGYRGGSGG----GGG----------GSSGGR 602
Query: 306 ALGSDCGGSSGSSSGSGPSAPTSSSVLGSGLVAPVSPYKPGQT 348
GS G S GS G G S+ S GS V VS G T
Sbjct: 603 --GSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVT 643
Score = 48.5 bits (114), Expect = 2e-05
Identities = 35/95 (36%), Positives = 39/95 (41%), Gaps = 1/95 (1%)
Query: 124 GKPDPSPSSKLSSVASNGGGAGGAGG-GAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPG 182
G S S S S GGG GG G G+ G G S G S+ S G
Sbjct: 526 GSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSG 585
Query: 183 SDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSA 217
+ GGGGGG GG G GGG S G R S+
Sbjct: 586 GYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSS 620
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/144 (32%), Positives = 47/144 (32%), Gaps = 28/144 (19%)
Query: 183 SDKKEPGGGGGGGGGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGML 242
S GGGGG GGGGG GF S GS S S S GG
Sbjct: 33 SSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS-----LVNLGGSKSISISVARGGGRG 87
Query: 243 SSAGGAPEGKDDKKDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGINVDVNQHPDGGP 302
S GG G G GG G GG GG G GGG G
Sbjct: 88 SGFGGGYGGG--------GFGGGGFGGGGFGGGGIG--------GGGFG-------GFGS 124
Query: 303 GGKALGSDCGGSSGSSSGSGPSAP 326
GG G G G G GP P
Sbjct: 125 GGGGFGGGGFGGGGYGGGYGPVCP 148
Score = 45.1 bits (105), Expect = 2e-04
Identities = 50/162 (30%), Positives = 56/162 (34%), Gaps = 50/162 (30%)
Query: 136 SVASNGGGAGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDKKEPGGGGGGG 195
S GGG+ GAGGG G K I V ++ G GGG GGG
Sbjct: 47 SSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISV---------ARGGGRGSGFGGGYGGG 97
Query: 196 GGGGGGGGGVSSEKSGFRVPSATCQPFTPRTGSPSSSASACSPGGMLSSAGGAPEGKDDK 255
G GGGG GG GF GG GG G
Sbjct: 98 GFGGGGFGG-----GGF--------------------------GG--GGIGGGGFG---- 120
Query: 256 KDTDVGGGGKGTGGASAEGGPTGLAHGRISCGGGI-NVDVNQ 296
G GG G GG GG G +G + GGI V +NQ
Sbjct: 121 ---GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQ 159
Score = 37.4 bits (85), Expect = 0.043
Identities = 29/79 (36%), Positives = 32/79 (40%), Gaps = 14/79 (17%)
Query: 131 SSKLSSVASNGGG-----AGGAGGGAAGDKDTKSGPLKLSDIGVEDKSSFKPYSKPGSDK 185
S +S + GGG GG GGG G G IG F + G
Sbjct: 73 SKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIG---GGGFGGFGSGG--- 126
Query: 186 KEPGGGGGGGGGGGGGGGG 204
GG GGGG GGGG GGG
Sbjct: 127 ---GGFGGGGFGGGGYGGG 142
Score = 33.5 bits (75), Expect = 0.62
Identities = 18/40 (45%), Positives = 21/40 (52%)
Query: 12 SSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
SS SGGG G GGGG + G+S G G GS +G
Sbjct: 530 SSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSG 569
Score = 33.1 bits (74), Expect = 0.82
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 8/57 (14%)
Query: 4 APSLSALRSSKHS--------GGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
AP++S S+ H+ GGGGGG G GG+ G+ G G G GS
Sbjct: 498 APNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554
Score = 32.0 bits (71), Expect = 1.8
Identities = 19/44 (43%), Positives = 20/44 (45%), Gaps = 1/44 (2%)
Query: 8 SALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAG 51
S S + GG GGGGGG SG S G G GSS G
Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIG-GRGSSSGG 622
Score = 31.6 bits (70), Expect = 2.4
Identities = 21/45 (46%), Positives = 23/45 (51%), Gaps = 5/45 (11%)
Query: 12 SSKHSGGG--GGGGGGGGADPAWTSALSG---NSSGPGPGSSPAG 51
SS SGGG G GGGGGG + + SG SG G G S G
Sbjct: 557 SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGG 601
Score = 30.8 bits (68), Expect = 4.1
Identities = 16/37 (43%), Positives = 17/37 (45%)
Query: 16 SGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGS 52
SGGGGGGG G + G S G G G GS
Sbjct: 541 SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGS 577
Score = 30.4 bits (67), Expect = 5.3
Identities = 18/53 (33%), Positives = 25/53 (47%)
Query: 1 MSTAPSLSALRSSKHSGGGGGGGGGGGADPAWTSALSGNSSGPGPGSSPAGST 53
+ST+ + + S+ GGGG G GG S SG G G GS +G +
Sbjct: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGS 557
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.131 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,777,476
Number of Sequences: 37866
Number of extensions: 2437320
Number of successful extensions: 52854
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 518
Number of HSP's successfully gapped in prelim test: 1013
Number of HSP's that attempted gapping in prelim test: 21332
Number of HSP's gapped (non-prelim): 15869
length of query: 646
length of database: 18,247,518
effective HSP length: 109
effective length of query: 537
effective length of database: 14,120,124
effective search space: 7582506588
effective search space used: 7582506588
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.