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Search of human proteins with 24308394
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
(664 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308394 hypothetical protein LOC140893 [Homo sapiens] 1348 0.0
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap... 138 2e-32
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 138 2e-32
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 138 2e-32
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 75 2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni... 74 6e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 71 3e-12
gi|210032580 SET domain containing 1B [Homo sapiens] 66 1e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 4e-10
gi|150170670 piccolo isoform 2 [Homo sapiens] 62 2e-09
gi|150378539 piccolo isoform 1 [Homo sapiens] 62 2e-09
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 62 2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 1e-08
gi|188536004 zinc finger protein 469 [Homo sapiens] 59 2e-08
gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 58 3e-08
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 5e-08
gi|91208420 bassoon protein [Homo sapiens] 56 9e-08
gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 56 9e-08
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 1e-07
gi|146219832 myosin light chain kinase 3 [Homo sapiens] 56 1e-07
gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 55 2e-07
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 55 2e-07
gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 55 3e-07
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 54 5e-07
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 5e-07
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 54 5e-07
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 5e-07
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 54 5e-07
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 54 5e-07
gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 54 5e-07
>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
Length = 664
Score = 1348 bits (3489), Expect = 0.0
Identities = 664/664 (100%), Positives = 664/664 (100%)
Query: 1 MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN 60
MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN
Sbjct: 1 MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN 60
Query: 61 LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE 120
LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE
Sbjct: 61 LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE 120
Query: 121 EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG 180
EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG
Sbjct: 121 EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG 180
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN
Sbjct: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300
GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL
Sbjct: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300
Query: 301 QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA 360
QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA
Sbjct: 301 QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA 360
Query: 361 QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA 420
QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA
Sbjct: 361 QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA 420
Query: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480
GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ
Sbjct: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480
Query: 481 SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP 540
SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP
Sbjct: 481 SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP 540
Query: 541 PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600
PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP
Sbjct: 541 PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600
Query: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP
Sbjct: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
Query: 661 WEET 664
WEET
Sbjct: 661 WEET 664
>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
sapiens]
Length = 867
Score = 138 bits (347), Expect = 2e-32
Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%)
Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63
F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V
Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123
LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++
Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
+ ++ D+ A+ E P SP+ S G + K E+ H
Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191
>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 138 bits (347), Expect = 2e-32
Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%)
Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63
F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V
Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123
LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++
Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
+ ++ D+ A+ E P SP+ S G + K E+ H
Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191
>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 138 bits (347), Expect = 2e-32
Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%)
Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63
F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V
Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123
LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++
Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
+ ++ D+ A+ E P SP+ S G + K E+ H
Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 75.1 bits (183), Expect = 2e-13
Identities = 149/693 (21%), Positives = 239/693 (34%), Gaps = 88/693 (12%)
Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQ-RIEELFSKNHQLREQQKTLKENLR 62
FM L L ++ + G+ + LEL E + Q E+L S Q ++ K KE
Sbjct: 101 FMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKE 160
Query: 63 VLENRLRAGLCDRCMVTQELARKRQ-----QEFESSHLQNLQRIFILTNEMNGLKEENET 117
+ R ++ + +R+ +E + SH ++ + + +++ +T
Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220
Query: 118 LKEEVKRLRVLGDRPKPRAKEGTSD---PPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQ 174
E+ V P + TSD P P +P P K P + ++++ +
Sbjct: 221 --PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP--------KEPSPEKNSKKEKE 270
Query: 175 GVGLRGEEKPAGHRTSPVAKISPGATLPE----SRAPDMSPQRISNQLHGTIAVVRPGSQ 230
R + S SP T P SR+ SP+R RP +
Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR------------RPSPR 318
Query: 231 ACPADRG---PANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVD 287
P+ R P PPP RS P R + S +S S+ + PK PK
Sbjct: 319 RRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Query: 288 RLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQ 347
+ P SP +SP PS P K R + P + + +
Sbjct: 379 S----SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT---PQQSNRTRKSRVSVS 431
Query: 348 DLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALA 407
R G + + + + S P +P E+ SE E++G + A A
Sbjct: 432 PGRTSGKV------TKHKGTEKRESPSPAPKPRKVEL---------SESEEDKGGKMAAA 476
Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKP----LDLSEWGRARGQD-----TPKP 458
+ ++ + + +++++D ++P + E GR R +P P
Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSSED---ERPKRSHVKNGEVGRRRRHSPSRSASPSP 533
Query: 459 AGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPM------DP 512
+ SP SP PP + SP + P + +P P
Sbjct: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593
Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK---AEVLRPE 569
R P Q S P T P PPP + P P P H P K + V +
Sbjct: 594 RRYSPPIQRRYS-PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRR 652
Query: 570 SDELDETDTPGSEVGLSSQAEATTSTT---GEGPECICTQEHGQGPPRKRKRASEPGDKA 626
S L GS S++ + P Q PP +R +S P +
Sbjct: 653 SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQ 712
Query: 627 SKKPS-RGRRKLTATEGPGSPRDAEDHSPSPNS 658
S PS R R+++ T P + A SPSP S
Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAA--SPSPQS 743
Score = 48.9 bits (115), Expect = 1e-05
Identities = 51/216 (23%), Positives = 83/216 (38%), Gaps = 21/216 (9%)
Query: 464 SLSPAAAHTASPEPPTQSGPL--------TRSPQALSNGTKGTRVPEQEEASTPMDPSRP 515
S SP + SP P +S P+ +RSP+ + + PE++E TP
Sbjct: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE-KTP-----E 222
Query: 516 LPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK-AEVLRPESDELD 574
LP + + P E T L P P+P P P+ P + + + K E RP S
Sbjct: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282
Query: 575 ETDT---PGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRK---RKRASEPGDKASK 628
++ + S + + + P + P R+ R+ P + S+
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342
Query: 629 KPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET 664
P R RR+ +A+ S + S SP P + T
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378
Score = 38.1 bits (87), Expect = 0.026
Identities = 47/190 (24%), Positives = 69/190 (36%), Gaps = 38/190 (20%)
Query: 455 TPKPAGQHG-SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513
+P+P +H S P A T+S PP + G + SPQ + + TR P + + TP +P
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGA-SSSPQRRQSPSPSTR-PIRRVSRTP-EPK 731
Query: 514 R------PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE-PSKAEVL 566
+ P P S +SS S PP P P Q P + P P K
Sbjct: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK---- 787
Query: 567 RPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA 626
+A + T P QE G +K+K DK
Sbjct: 788 -----------------------KAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824
Query: 627 SKKPSRGRRK 636
KK + +++
Sbjct: 825 HKKHKKHKKE 834
Score = 36.2 bits (82), Expect = 0.100
Identities = 52/234 (22%), Positives = 72/234 (30%), Gaps = 38/234 (16%)
Query: 457 KPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPL 516
+P+ Q + + PEP + P SP+ K ++ +++E + P SR
Sbjct: 232 EPSVQEATSTSDILKVPKPEPIPE--PKEPSPE------KNSKKEKEKEKTRPRSRSRSK 283
Query: 517 PGSQLSLSSPGSTEDE-----------DTGRPLPPPHPQP----PPHPQPPDLDGHPEPS 561
S+ SP T RP P P P PP PP S
Sbjct: 284 SRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRS 343
Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
R S L + + S S + T P PPR+R R S
Sbjct: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP 403
Query: 622 PGDKASK-------KPSRGRRKLTATEGPGSPR--------DAEDHSPSPNSSP 660
P K + S RK + PG + SPSP P
Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 73.6 bits (179), Expect = 6e-13
Identities = 138/577 (23%), Positives = 185/577 (32%), Gaps = 80/577 (13%)
Query: 129 GDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188
G + P A + PPSP P+P A+T P +GV L +E P
Sbjct: 845 GSKDSP-ATTHSPTPPSPKGAPTPS---AVTPLSP----------KGVTLPPKETP---- 886
Query: 189 TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANG-TPP--- 244
T V + P + AP +P A P + PA P TPP
Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946
Query: 245 ----------------PLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDR 288
P P ++PPSP + G + S A P A T +PK P
Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSP--KGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004
Query: 289 LCLLNRPLSLHLQSPHSSPLA----------PAAAPSDPRLQDLKAREAEAWEEPTELLG 338
P ++ SP SP A PAA P P+ A T
Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK-GSPAATPLPKGAPTTPAAT 1063
Query: 339 LPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGP- 397
LPS G L+GA A + + P+G P P P P G + P
Sbjct: 1064 LPSPKGGPATPSLKGA-PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122
Query: 398 ENEGTRAALAAAGLSGGRHTQP--AGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDT 455
+ T A GG T P P T + A P A
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA---TP 1179
Query: 456 PKPAGQHGSLSPAAAHT--ASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513
P P G + SP A T A+ P + G T SP+ T + +TP
Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239
Query: 514 RPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQP-PPHPQPPDLDG------HPEPSKAEV 565
P ++P +T G P PPP P PP PP L G H V
Sbjct: 1240 AP--------TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291
Query: 566 LRPESDELDETDTP--GSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPG 623
+ P S + +P G+ ++ + + G P PP + + P
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351
Query: 624 DKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
S K G ++ EGP P H P +P
Sbjct: 1352 TTPSSK--GGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386
Score = 70.1 bits (170), Expect = 6e-12
Identities = 138/561 (24%), Positives = 187/561 (33%), Gaps = 61/561 (10%)
Query: 134 PRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193
P + +G PSP P+P A+T P G A +G PA T P
Sbjct: 993 PPSPKGGPATPSPKGAPTP---PAVTPPSPKGSPAATPFPKGAST----PPAA--TPPSP 1043
Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPA------DRGPANGTP--PP 245
K SP AT AP + + G G+ PA GPA +P P
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 246 LPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPK-----LSPKVDRLCLLNRPLS--- 297
+P ++PPSP + GL+ A A T +PK PK P S
Sbjct: 1104 MPPAATPPSP--KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161
Query: 298 -LHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALH 356
L P +P PAA P P+ A + T PS G+ +GA
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPK--GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-P 1218
Query: 357 LLLAQQQLRARARAGSVRPRGQP-TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGR 415
A + + P+G P TP PS G + P+ T A L GG
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278
Query: 416 HTQP--AGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHT- 472
T P P A T + A P A P P G G+ P A T
Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA---TPPSPKGSPGTPPPKGAPTP 1335
Query: 473 ASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP------------MDPSRPLPGSQ 520
+ PP+ G T P + G P +E TP M P P G
Sbjct: 1336 PAVTPPSPKGTPT-LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394
Query: 521 LSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPG 580
+ S + + T + P P+ P P +G PSK ++ P + P
Sbjct: 1395 IP-----SPKGDPTSPAVIPLSPKKAP-ATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448
Query: 581 SEVGLSSQAEATTSTTGEGPECICTQEHGQGPPR-KRKRASEPGDKASKKPSRGRRKLTA 639
+ AT S+ G+ T + PP K+ S KA P+
Sbjct: 1449 TSA--PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506
Query: 640 TEGPGSPRDAEDHSPSPNSSP 660
P SP++ +PS P
Sbjct: 1507 AVIPSSPKEV-PATPSSRRDP 1526
Score = 51.6 bits (122), Expect = 2e-06
Identities = 108/459 (23%), Positives = 145/459 (31%), Gaps = 67/459 (14%)
Query: 221 TIAVVRPGSQACPADRGPANGTPP-----------------PLPARSSPPSPAYERGLSL 263
T+ +V S+ CP P N P LP +PP G+S
Sbjct: 697 TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756
Query: 264 DSFLR--ASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQD 321
S L AS P E P L+ SP SPL + +P R
Sbjct: 757 TSALAPVASSPK----ECPTEDSGASATASSKGTLTYLADSP--SPLGVSVSPQTKRPPT 810
Query: 322 LKAREAEAWEEPTELLGLPSALAGMQDLRL-EGALHLLLAQQQLRARARAGSVRPRGQPT 380
K T + L S ++ ++ L E +L ++ P+G PT
Sbjct: 811 KKGSAGP----DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866
Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440
P + P P G P+ T + + G PA P Q + T
Sbjct: 867 PSAVTPLSPKGVTLP-PKETPTPSVVNLPFPKEG----PATPAPKQAPALSMTSSSP--- 918
Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHT--ASPEPPTQSGPLTRSPQALSNGTKGT 498
+ + TP P G S SP A T A+ P + GP T SP+ T
Sbjct: 919 ---------KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969
Query: 499 RVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQP-PPHPQPPDLDG 556
+ +TP P P P +T G P P P P PP PP
Sbjct: 970 PPSPKGGPATPSPKGAPTP--------PAATPPSPKGGPATPSPKGAPTPPAVTPPS--- 1018
Query: 557 HPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKR 616
P+ S A P+ TP S G AT G T +G P
Sbjct: 1019 -PKGSPAATPFPKGASTPPAATPPSPKG---SPAATPLPKGAPTTPAATLPSPKGGPATP 1074
Query: 617 KRASEPGDKASKKPS-RGRRKLTATEGPGSPRDAEDHSP 654
P A+ PS +G + +G P A SP
Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113
Score = 50.4 bits (119), Expect = 5e-06
Identities = 119/532 (22%), Positives = 185/532 (34%), Gaps = 83/532 (15%)
Query: 132 PKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSP 191
P P+ +S P P+P G + P +E R P
Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS------------RRDP 1526
Query: 192 VAKISPGATLPESRAP-DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR- 249
+A P ATL + P ++P+ A++ P + PA TP PA
Sbjct: 1527 IA---PTATLLSKKTPATLAPKE---------ALIPPAMTVPSPKKTPAIPTPKEAPATP 1574
Query: 250 -----SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPH 304
SSPP+ S P A+T +PK +P + + +P
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634
Query: 305 SSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLG--LPSALAGMQDLRLEGALHLLLAQQ 362
+P +P PS L+D A T +G +P A G+ + AL +L
Sbjct: 1635 GTPTSPPVTPSS--LKDSPTSPASV----TCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 363 Q------LRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRH 416
+ A R G + T + P + S+GP + A L +
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748
Query: 417 TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE 476
+ + + A + A PL + + + PKP +A+ +A+P
Sbjct: 1749 AKGKDASHSPKGPLAPPESKA-STPLTAAAFEKV----LPKPE--------SASVSAAPS 1795
Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536
PP S PL SP T P+Q+ P P L S S P + DED
Sbjct: 1796 PPV-SLPLAPSPVP-------TLPPKQQ--FLPSSPGLVLE----SPSKPLAPADEDELL 1841
Query: 537 PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRP---------ESDELDETDTPGSEVGLSS 587
PL PP P P L P P A + P ++++ T++ E
Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPEL 1901
Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSR-GRRKLT 638
+ + +T T + + E + P K K+ S KA K S+ G R++T
Sbjct: 1902 EEQDSTQATTQQAQLAAAAEIDEEPVSKAKQ-SRSEKKARKAMSKLGLRQVT 1952
Score = 29.6 bits (65), Expect = 9.3
Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 7/121 (5%)
Query: 197 PGATLPE--SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254
PG TLP S AP P +NQ + S P + + LP ++P +
Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPF-PQSSSGTALPLGTAPEA 99
Query: 255 PAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAP 314
P + L P+A+ +P ++P + + PL+L +PHS + A P
Sbjct: 100 PTFLPNLIGPPI----SPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP 155
Query: 315 S 315
+
Sbjct: 156 N 156
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 71.2 bits (173), Expect = 3e-12
Identities = 149/575 (25%), Positives = 193/575 (33%), Gaps = 110/575 (19%)
Query: 131 RPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188
RP P A+ PP+ P S + TE P G GL ++PA
Sbjct: 182 RPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAARRRPSA---GGGL---QRPASRS 232
Query: 189 TSPVAK--ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS------QACPADRGPAN 240
S A SP + P +R +P S + +RP A PA GP +
Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLS 291
Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPL--SL 298
+P P+ S+PPSP ++ PS T +P +P L P +
Sbjct: 292 SSPLATPSPSAPPSP-------------SAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338
Query: 299 H--LQSPHSSPLA--PAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354
H L SP SPLA P AP L L+A + P L PS A A
Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-----ALA 393
Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGG 414
+HLL A P+P P P S P T + A L+
Sbjct: 394 VHLLQAPFS-------------PPPSPPVQAPFSPPASPPVSP--SATPPSQAPPSLAAP 438
Query: 415 RHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG-------------QDTPKPAGQ 461
P P + +AT PL A+ Q P P
Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498
Query: 462 ---HGSLSPAAAHTASP--EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR-- 514
SP+A+ SP PP Q+ P+ +P +VP AS + R
Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL--------LQVPPSPPASPTLQAPRRP 550
Query: 515 PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELD 574
P PG S+S P T G P PPP P PDL GH S + PE
Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPP-PPPSRSPSSTLSGPDLAGH---SSSATSTPE----- 601
Query: 575 ETDTPGSEVGLSSQAEATTSTTGEGPEC-ICTQEHGQGPPRKRKRASEPGDKASKKPSRG 633
+ G + G A A+ E C G PP + A PG P+ G
Sbjct: 602 --ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWPPATG 657
Query: 634 RRK------LTATEGPGSPRDAE---DHSPSPNSS 659
+ TEGP S A D PSP +S
Sbjct: 658 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 692
Score = 54.7 bits (130), Expect = 3e-07
Identities = 129/552 (23%), Positives = 171/552 (30%), Gaps = 86/552 (15%)
Query: 117 TLKEEVKRLRVLGDRPKPRAKEGTSDPP----SPLLLPSPGGWKAITEKPPGGHEEAEED 172
T+ E R P + G PP SP + SPG T P G +
Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128
Query: 173 HQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQA- 231
+ RG+ A R++ A + P P + R S + + RP A
Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188
Query: 232 -CPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS------- 283
P GP ++ PSPA R S L+ +++ A LS
Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248
Query: 284 --------------PKVDRLCLLNRP--------LSLHLQSPHSSPLA---PAAAPS--- 315
PK L L P + L SSPLA P+A PS
Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308
Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRP 375
P LQ L + A + T LG P+ A H L L A P
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTL----------QATHSFLPSPPLSPLATPPPQAP 358
Query: 376 RGQPTPGEMLPSLPVGSDSEGP---ENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAA 432
P P P S P + ALA L P+ P +A + A+
Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418
Query: 433 TQDCALDKPLDLSEWGRARG--QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490
P + A Q P P SP + +A+P PP PL P
Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMSPSATP-PPQAPPPLAAPPLQ 472
Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL--SSPGSTEDEDTGRPLPPPHPQPPPH 548
L+ + P Q + P + LP S +P S PL P PQ PP
Sbjct: 473 LA------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526
Query: 549 PQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEH 608
P L P P + L+ TPG + +S GP
Sbjct: 527 LAAPLLQVPPSPPASPTLQAPR----RPPTPGPDTSVS------------GPRLTLALAP 570
Query: 609 GQGPPRKRKRAS 620
G PP R +S
Sbjct: 571 GPPPPPSRSPSS 582
Score = 49.7 bits (117), Expect = 9e-06
Identities = 94/363 (25%), Positives = 115/363 (31%), Gaps = 85/363 (23%)
Query: 365 RARARAGSV-RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG---------- 413
R +A+AG+ R PG + P P P L AAG G
Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64
Query: 414 -GRHTQP-----AGPGRAQRTEAAATQDCALD----KPLDLSEWGRARGQDTPKPAGQHG 463
G T P AGP R R A+ + A P +S GRA G P P GQ G
Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124
Query: 464 ---------------------SLSPAAAH-TASPEPPTQSGPLTRSPQALSNG------- 494
+LS A T+ P P T S + R +A
Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 495 --------TKGTR--VPEQEEAST--PMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH 542
T+G R V E ST P +R P + L P S + PL P
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244
Query: 543 PQPPPHPQPPDLDGH---PEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEG 599
P P H P+P + LRP D + LSS AT S +
Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--- 301
Query: 600 PECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHS--PSPN 657
PP + S P S+ AT GSP HS PSP
Sbjct: 302 -----APPSPSAPPSLQTLPSPPATPPSQ----------ATTSLGSPTLQATHSFLPSPP 346
Query: 658 SSP 660
SP
Sbjct: 347 LSP 349
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 65.9 bits (159), Expect = 1e-10
Identities = 128/518 (24%), Positives = 184/518 (35%), Gaps = 88/518 (16%)
Query: 155 WKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD-----M 209
+++ +E P E+ EE + EE+ VA+ S + PE D +
Sbjct: 1121 FESSSESSPSSSEDEEEV-----VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175
Query: 210 SPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS----PAYERGLSLD- 264
+P + G V ++A + P+ PPLP P+ P E GLS +
Sbjct: 1176 APGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEG 1235
Query: 265 SFLRASRPSAMTHEA-PKLSPK--------VDRLCLLNRPLSLHLQSPHSSPLAPAAAPS 315
+ L + P A EA P LSP+ V+ + PL L P P P + P
Sbjct: 1236 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295
Query: 316 DPRLQDLK----AREAEAWEEPTELLGLPSALAGMQDLRLE------------GALHLLL 359
+P D E A + P GL +LA Q G+ L L
Sbjct: 1296 EPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSL 1355
Query: 360 AQQQLRAR-----ARAGSVRPRGQP-TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG 413
+ Q+ A + S+ G P TPG P S+ GP L L
Sbjct: 1356 SSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP------LLLPVCPLPT 1409
Query: 414 GRHTQPAGP-GRAQRTEAAATQDCALDKPLDLSEWGRARGQ---DTPKPAGQHGSLS--- 466
GR + +GP E L PL L+ R Q TP P L+
Sbjct: 1410 GRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCP 1469
Query: 467 ------PAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQ 520
P + P + GPL R P + G + +P Q + TP+ PS P +
Sbjct: 1470 PPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ--TPVFPSTHDPRTV 1527
Query: 521 LSLSSPGSTEDEDTGRPLPPPH--PQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDT 578
+ + + G P PPP PQPPP P PP + EP+K ++ E
Sbjct: 1528 -------TLDFRNAGIPAPPPPLPPQPPPPPPPPPV----EPTKLPFKELDNQWPSEAIP 1576
Query: 579 PGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKR 616
PG T E E ++ + PP+KR
Sbjct: 1577 PG--------PRGRDEVTEEYMELAKSRGPWRRPPKKR 1606
Score = 51.6 bits (122), Expect = 2e-06
Identities = 93/396 (23%), Positives = 132/396 (33%), Gaps = 73/396 (18%)
Query: 211 PQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRAS 270
P + Q T A P +QA PA + +P P PP P E + +F +
Sbjct: 367 PFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPP--EEPTATAAF--GA 422
Query: 271 RPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAW 330
R S AP P L L + P + P P P D +L R W
Sbjct: 423 RDSGEFRRAPAPPP-------LPPAEPLAKEKPGTPPGPP---PPDTNSMELGGRPTFGW 472
Query: 331 E-EPTELLGLP---SALAGMQDLR--LEGALHLLLAQQQ-----LRARARAGSVRPRGQP 379
EP + G P S+ AG + L+ + +LL +Q+ LR ++ G P
Sbjct: 473 SPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP 532
Query: 380 ---TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDC 436
+ ++ P P G++S+ P G + +G P D
Sbjct: 533 ISSSSSQLSPLAPFGTNSQ-PGFRGPTPPSSRPSSTGLEDISPT-----------PLPDS 580
Query: 437 ALDKPLDLSEWGRARGQD-TPKPAGQHGSLSPAAAHTASPEPPTQ--------------- 480
D+ LDL R + P PAG + A PT
Sbjct: 581 DEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDME 640
Query: 481 -------SGPLTRS----PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGST 529
S P+T + P ++ G P + P+ P P L P
Sbjct: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP----PLPPPPPP 696
Query: 530 EDEDTGRPLPPPHPQPPPHPQP--PDLDGHPEPSKA 563
G P+PPP P PPP P P P + P P A
Sbjct: 697 PPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 63.9 bits (154), Expect = 4e-10
Identities = 153/592 (25%), Positives = 196/592 (33%), Gaps = 114/592 (19%)
Query: 131 RPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188
RP P A+ PP+ P S + TE P G GL ++PA
Sbjct: 191 RPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAARRRPSA---GGGL---QRPASRS 241
Query: 189 TSPVAK--ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPA-DRGPANG---- 241
S A SP + P +R +P S + +RP P D PA G
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 242 ----TPPP---LPARSSPPSPAYERGLSLDSFLR----------ASRPSAMTHEAPKLSP 284
TP P L +++ P PA SL L ++ PS T +P +P
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361
Query: 285 KVDRLCLLNRPL--SLH--LQSPHSSPLA--PAAAPSDPRLQDLKAREAEAWEEPTELLG 338
L P + H L SP SPLA P AP L L+A + P L
Sbjct: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Query: 339 LPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPE 398
PS A A+HLL A P+P P P S P
Sbjct: 422 TPSPQAPNAL-----AVHLLQAPFS-------------PPPSPPVQAPFSPPASPPVSPS 463
Query: 399 NEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKP 458
T + A L+ P P + +AT PL A+ P
Sbjct: 464 --ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521
Query: 459 A-----------------GQHGSLSPAAAHTASP--EPPTQSGPLTRSPQALSNGTKGTR 499
A GQ SP+A+ SP PP Q+ P+ +P +
Sbjct: 522 ALATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPPPQAPPVLAAPLL--------Q 572
Query: 500 VPEQEEASTPMDPSR--PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH 557
VP AS + R P PG S+S P T G P PPP P PDL GH
Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRSPSSTLSGPDLAGH 631
Query: 558 PEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPEC-ICTQEHGQGPPRKR 616
S + PE + G + G A A+ E C G PP
Sbjct: 632 ---SSSATSTPE-------ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 617 KRASEPGDKASKKPSRGRRK------LTATEGPGSPRDAE---DHSPSPNSS 659
+ A PG P+ G + TEGP S A D PSP +S
Sbjct: 682 RGA--PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731
Score = 52.8 bits (125), Expect = 1e-06
Identities = 90/331 (27%), Positives = 107/331 (32%), Gaps = 57/331 (17%)
Query: 369 RAGSVRPRGQ---------PTPGEMLPSLPVGSDSEGPENEGTRAALAAA----GLSGGR 415
RAG R G P G + P + S GP + RA+ G G R
Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 416 HTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLS-------PA 468
+ R + TEA + D S G G TP PA S + P
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTS--GPTPG--TPSPAMARRSRAAGTEVGLPR 191
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST----PMDPSRPLPGSQLSLS 524
A +A P PPT+ GP A + T + S SR L S LS
Sbjct: 192 PAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 525 SPGSTEDEDTGRPLPPPHP-QPPPHP----QPPDLDGHPEPSKAEVLRPESDELDETDTP 579
SP + G P P HP QP P +PP + P A L P S TP
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSS--SPLATP 307
Query: 580 GSEVGLSSQAEATTSTTGEGPECIC--------TQEHGQGPPRKRKRASEPGDKASKKPS 631
L SQA T T C PP + S P S+
Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ--- 364
Query: 632 RGRRKLTATEGPGSPRDAEDHS--PSPNSSP 660
AT GSP HS PSP SP
Sbjct: 365 -------ATTSLGSPTLQATHSFLPSPPLSP 388
Score = 52.8 bits (125), Expect = 1e-06
Identities = 134/566 (23%), Positives = 174/566 (30%), Gaps = 118/566 (20%)
Query: 134 PRAKEGTSDPP----SPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRT 189
P + G PP SP + SPG T P G + + RG+ A R+
Sbjct: 95 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 154
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACP---------------- 233
+ A + P P + R S + + RP A P
Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214
Query: 234 ---------ADRGPANG---------------TPPPLPARSSPPSPAYERGLSLDS---- 265
A R P+ G TP PARS P + R + S
Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274
Query: 266 -FLRASRPSAMT----HEAPKLSPKVDRLCLLNRPLSLHLQS---------PHSS----- 306
L+A RP +T AP L P P S LQS PHSS
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SAALQSQAPPTLPATPHSSSLTCQ 333
Query: 307 -----PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQ 361
PLAP + + P LQ L + A + T LG P+ A H L
Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL----------QATHSFLPS 383
Query: 362 QQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGP---ENEGTRAALAAAGLSGGRHTQ 418
L A P P P P S P + ALA L
Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG--QDTPKPAGQHGSLSPAAAHTASPE 476
P+ P +A + A+ P + A Q P P SP + +A+P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMSPSATP- 497
Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL--SSPGSTEDEDT 534
PP PL P L+ + P Q + P + LP S +P S
Sbjct: 498 PPQAPPPLAAPPLQLA------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551
Query: 535 GRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTS 594
PL P PQ PP P L P P + L+ TPG + +S
Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR----RPPTPGPDTSVS-------- 599
Query: 595 TTGEGPECICTQEHGQGPPRKRKRAS 620
GP G PP R +S
Sbjct: 600 ----GPRLTLALAPGPPPPPSRSPSS 621
Score = 51.6 bits (122), Expect = 2e-06
Identities = 136/572 (23%), Positives = 184/572 (32%), Gaps = 119/572 (20%)
Query: 130 DRPKPRAKEGTSDPPSP-LLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188
D+ K A T +P LL P P G + +PP A G KP R
Sbjct: 6 DKAKAGAAARTPAARAPGLLTPRPPG----SPRPPPPVTPAALRVLGAAGAVGRKPLAER 61
Query: 189 TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLP- 247
+ GAT+PES AP P R + GT S PA R PA+G P
Sbjct: 62 AGGIG----GATIPES-APRAGPTRSA----GT-------SSRNPASRPPASGRGERAPP 105
Query: 248 ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSP 307
A+++ P P G + + +RP + + ++S +
Sbjct: 106 AKNTSPGPVSSPGRASGT----TRPGPLGQKGLRISAE--------------------ET 141
Query: 308 LAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRAR 367
+A A P+ L A PT G PS +A++ A
Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTP--GTPSPA---------------MARRSRAAG 184
Query: 368 ARAGSVRPR--GQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRA 425
G RP +P P P V S SE E + AA GG +PA R+
Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-RPAS--RS 241
Query: 426 QRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHG----SLSPAAAHTASPEPPTQS 481
+ A A P PKP G ++P A P S
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301
Query: 482 GPL-TRSPQALSNGTKGTRVPEQEEAS-------TPMD---PSRPLPGSQLSLSSPGSTE 530
PL T SP A +P +S TP+ PS P S +L SP +T
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361
Query: 531 DEDTGR--------------------PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPES 570
PL P PQ PP P L P P + L P +
Sbjct: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Query: 571 DELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKP 630
T +P + L+ + P + PP AS P ++ P
Sbjct: 422 -----TPSPQAPNALAVHLLQAPFSPPPSPPV----QAPFSPP-----ASPPVSPSATPP 467
Query: 631 SRGRRKLTA--TEGPGSPRDAEDHSPSPNSSP 660
S+ L A + P SP + SPS P
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 61.6 bits (148), Expect = 2e-09
Identities = 113/473 (23%), Positives = 168/473 (35%), Gaps = 63/473 (13%)
Query: 93 SHLQNLQRIFILTNEMN--GLKEENETLKEEV--KRLRVLGDRPKPRAKEGTSDPPSPLL 148
S + L + + N+ N L ++E +EE K+ V ++ KP EG PP
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP---EGIIKPPLQQQ 214
Query: 149 LPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD 208
P P I ++ G + ++D G K + K P T + P
Sbjct: 215 PPKP-----IPKQQGPGRDPLQQD-------GTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
Query: 209 MSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP--------SPAYERG 260
+PQ +L RP ++ RG + P LP+ S PP PA + G
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGES--VKPSLPSPSKPPIQQPTPGKPPAQQPG 320
Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320
A P+ + L+ + + +P P + PL PA P+
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPA----- 373
Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380
+ E+P+ P ALA + A QQ A+ V G P
Sbjct: 374 -----QQTGSEKPSSEQPGPKALAQPPGVGKTPA------QQPGPAKPPTQQV---GTPK 419
Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440
P P L + + GP T+ + G G Q AGPG+ + T+ +
Sbjct: 420 PLAQQPGLQSPAKAPGP----TKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPS-QL 473
Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQS-GPLTRSPQALSNGTKGTR 499
P + G P P Q GS P + S +PP Q GP SPQ + T+
Sbjct: 474 PGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS----TK 528
Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552
P Q+ S +P P + S +G+PL PP P QPP
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPP 580
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/290 (23%), Positives = 92/290 (31%), Gaps = 66/290 (22%)
Query: 371 GSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEA 430
G+ +P QP P+ GS+ E G +A G+ G Q GP +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP---- 411
Query: 431 AATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490
TQ KPL A Q G SPA A + P Q GP Q
Sbjct: 412 --TQQVGTPKPL----------------AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ 550
G + + P P LPG P PP QP P
Sbjct: 454 AGPGKTSA------QQTGPTKPPSQLPG------------------PAKPPPQQPGPAKP 489
Query: 551 PPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610
PP +P A +P S + T P + G A+ + G T+ Q
Sbjct: 490 PPQ-----QPGSA---KPPSQQPGSTKPPPQQPG---PAKPSPQQPGS------TKPPSQ 532
Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
P + A +P +K ++ K + G G P SPS P
Sbjct: 533 QPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Score = 46.6 bits (109), Expect = 7e-05
Identities = 137/650 (21%), Positives = 217/650 (33%), Gaps = 121/650 (18%)
Query: 116 ETLKEEVKRLRVLGDRPKPRAKE-----GTSDPPSPLLLPSPGGWKAITEKPPGGHEEAE 170
+T + + +L + D +P+ K+ G S PS LPSP K ++P G A+
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS---LPSPS--KPPIQQPTPGKPPAQ 317
Query: 171 EDHQGVGLRGEEKPAGHR---TSPVAKIS---------PGATLPESR--------APDMS 210
+ G KP T P+A+ PG T P ++ A
Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377
Query: 211 PQRISNQLHGTIAVVRP-GSQACPADR-GPAN------GTPPPLPARSSPPSPAYERGLS 262
++ S++ G A+ +P G PA + GPA GTP PL + SPA G +
Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437
Query: 263 LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLH--LQSPHSSPLAPAAAPSDPRLQ 320
+ +A + P L + P P P P
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 321 DLKAREAEAWEEPTELLG----LPSALAGMQDLRLEGALHLLLAQQQLRARARAG-SVRP 375
+++ + + P + G P + + AQQ A+ A S +P
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 376 RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQD 435
Q G+ L V ++ P ++G + L P +A Q
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP--LCNTTELLLHVPEKANFNTCTECQT 615
Query: 436 -----CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTR---- 486
C + L+E + G L+P + SP+P ++ P+T
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS---SPQPKLKTAPVTTTSAV 672
Query: 487 ---SPQALSNGTKGTRVPEQEEASTPMDPSRPLP--------GSQLSLSSPGSTEDEDTG 535
SPQ K P+Q+ + P +P +P P GS S + E +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAP-EPKKPPPLVKQPTLHGSP-SAKAKQPPEADSLS 730
Query: 536 RPLPPPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDET------DTPGSEVGLSSQ 588
+P PP P P + P D P+ K +++P +D + + D P S+V SQ
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKV--QSQ 786
Query: 589 AEATTST---------------TGE-----------------------GPECICTQEHGQ 610
AE T+ TGE GP +
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
P +K++ + K S KP + PG A P+P SP
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Score = 43.5 bits (101), Expect = 6e-04
Identities = 54/215 (25%), Positives = 77/215 (35%), Gaps = 30/215 (13%)
Query: 452 GQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPL---TRSPQALSNGTKGTRVPEQEEAST 508
G+D + G S+S +PP P+ T++PQ T ++P Q +AS
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ-----TDHAKLPLQRDASR 280
Query: 509 PMDPSRPLP-GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH----PEPSKA 563
P + G + S P P PP QP P P GH P P+K
Sbjct: 281 PQTKQADIVRGESVKPSLPS---------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTSTTGE--GPECICTQEHGQGPPRKRKRASE 621
+P PG+ V Q TT + GP Q+ G P + +
Sbjct: 332 PA-QPSGLTKPLAQQPGT-VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP----SSEQ 385
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656
PG KA +P + GP P + +P P
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Score = 42.0 bits (97), Expect = 0.002
Identities = 84/408 (20%), Positives = 135/408 (33%), Gaps = 42/408 (10%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-LHGTIAVVRPGSQACPADRGPA 239
+ P +TSP +P L ++ P P + LHG+ + + PA
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 240 NGTPPPLPARS-----SPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
P +P+ + P + + + L +S + + P +
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 295 PLSLHLQSPHSS--PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLR-L 351
PL P S P +P D + A +++ P G S G + + +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSSESKGQKQVDPV 849
Query: 352 EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPS----LPVGSDSEGPENEGTRAALA 407
+ AQ ++ + A + P+G PTP P+ +P S P+ + R +L
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSP 467
++ +QP P Q T S GQ P P Q G +P
Sbjct: 909 LGSITDAPKSQPTTP---QETVTGKLFGFGASIFSQASNLISTAGQ--PGPHSQSGPGAP 963
Query: 468 AAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG 527
A +PPT GP + QA K +P ++E P Q
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKS--IPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 528 STEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE----PSKAEVL-RPES 570
TE +PPP L P+ P+K E +PES
Sbjct: 1022 ETE------------KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 41.2 bits (95), Expect = 0.003
Identities = 119/569 (20%), Positives = 199/569 (34%), Gaps = 86/569 (15%)
Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEK 161
++E G K+ + K+E + PKP AK +G+ PP P P+ G ++
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR--PTAGQTVPTPQQ 894
Query: 162 PPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISP-----GATLPESRAPDMS----PQ 212
P E++ +G + P T+P ++ GA++ + +S P
Sbjct: 895 SPKPQEQSRRFSLNLGSI-TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 213 RISNQLHGTIAVVRPGSQACPADRGP--ANGTPPPLPARSSP-----PSPAYERGLSLDS 265
S G P P +GP + G PP PA+S P +PA E+ L+
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK---LEP 1010
Query: 266 FLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKA 324
+ T K P D L P L + SP + P ++ +
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
Query: 325 REAEAWEEPTELLGLPSALAGMQDLRLEGALH---LLLAQQQLRARARAGSVRPRGQPTP 381
++ + TE L G + L Q Q + G +R
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 382 GEMLPSLPVGSDSEGPEN-------------------------EGTRAALAAAGLSGGRH 416
G +PV ++S + E + L+ +
Sbjct: 1131 GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190
Query: 417 T-QPAGPGRAQRTEAAATQDCALDKPLD-----LSEWGRARGQDTP------KPAGQHGS 464
T Q + ++ +A+A Q+ KPL + E + R ++ KP +
Sbjct: 1191 TDQKQEESKLEKDKASALQE---KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ--EEASTPMDPSRPLP-GSQL 521
L P A +A P Q L +S ++ RV + +E P LP G+
Sbjct: 1248 LLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQ 1304
Query: 522 SLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGS 581
SL ED+ T + + PQPP +P ++ E ++ E + + + P S
Sbjct: 1305 SLPK----EDDKTTKTIKE-QPQPPCTAKPDQVEPGKEKTEKE---DDKSDTSSSQQPKS 1356
Query: 582 EVGLSS---QAEATTSTTGEGPECICTQE 607
GLS ++ +S+ GE P I T E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385
Score = 35.0 bits (79), Expect = 0.22
Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 25/140 (17%)
Query: 500 VPEQEEASTPMDPS-----RPLPGSQLSLSSPG-------------STEDEDTGRPLPPP 541
+P +E+ ST S + P SQL SP S+ + + +P PPP
Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409
Query: 542 HPQPPPHPQPPDLDGHPEP---SKAEVLRPESD----ELDETDTPGSEVGLSSQAEATTS 594
P PPP P PP P P S + P+ T TP + + + A
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 595 TTGEGPECICTQEHGQGPPR 614
+ G ICT PP+
Sbjct: 2470 SNGLPVTRICTTAPPPVPPK 2489
Score = 29.6 bits (65), Expect = 9.3
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
Query: 190 SPVAKISPGATLPESRAP-------DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGT 242
SP++ +SPG L + P D+SPQ++ LH +A V P S +
Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKV---LHPDMAKVPPASPKTAKMMQRSMSD 3681
Query: 243 PPPLPARSSPPSPA 256
P PL + S A
Sbjct: 3682 PKPLSPTADESSRA 3695
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 61.6 bits (148), Expect = 2e-09
Identities = 113/473 (23%), Positives = 168/473 (35%), Gaps = 63/473 (13%)
Query: 93 SHLQNLQRIFILTNEMN--GLKEENETLKEEV--KRLRVLGDRPKPRAKEGTSDPPSPLL 148
S + L + + N+ N L ++E +EE K+ V ++ KP EG PP
Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP---EGIIKPPLQQQ 214
Query: 149 LPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD 208
P P I ++ G + ++D G K + K P T + P
Sbjct: 215 PPKP-----IPKQQGPGRDPLQQD-------GTPKSISSQQPEKIKSQPPGTGKPIQGPT 262
Query: 209 MSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP--------SPAYERG 260
+PQ +L RP ++ RG + P LP+ S PP PA + G
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGES--VKPSLPSPSKPPIQQPTPGKPPAQQPG 320
Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320
A P+ + L+ + + +P P + PL PA P+
Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPA----- 373
Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380
+ E+P+ P ALA + A QQ A+ V G P
Sbjct: 374 -----QQTGSEKPSSEQPGPKALAQPPGVGKTPA------QQPGPAKPPTQQV---GTPK 419
Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440
P P L + + GP T+ + G G Q AGPG+ + T+ +
Sbjct: 420 PLAQQPGLQSPAKAPGP----TKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPS-QL 473
Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQS-GPLTRSPQALSNGTKGTR 499
P + G P P Q GS P + S +PP Q GP SPQ + T+
Sbjct: 474 PGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS----TK 528
Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552
P Q+ S +P P + S +G+PL PP P QPP
Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPP 580
Score = 48.5 bits (114), Expect = 2e-05
Identities = 69/290 (23%), Positives = 92/290 (31%), Gaps = 66/290 (22%)
Query: 371 GSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEA 430
G+ +P QP P+ GS+ E G +A G+ G Q GP +
Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP---- 411
Query: 431 AATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490
TQ KPL A Q G SPA A + P Q GP Q
Sbjct: 412 --TQQVGTPKPL----------------AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ 550
G + + P P LPG P PP QP P
Sbjct: 454 AGPGKTSA------QQTGPTKPPSQLPG------------------PAKPPPQQPGPAKP 489
Query: 551 PPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610
PP +P A +P S + T P + G A+ + G T+ Q
Sbjct: 490 PPQ-----QPGSA---KPPSQQPGSTKPPPQQPG---PAKPSPQQPGS------TKPPSQ 532
Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
P + A +P +K ++ K + G G P SPS P
Sbjct: 533 QPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580
Score = 46.6 bits (109), Expect = 7e-05
Identities = 137/650 (21%), Positives = 217/650 (33%), Gaps = 121/650 (18%)
Query: 116 ETLKEEVKRLRVLGDRPKPRAKE-----GTSDPPSPLLLPSPGGWKAITEKPPGGHEEAE 170
+T + + +L + D +P+ K+ G S PS LPSP K ++P G A+
Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS---LPSPS--KPPIQQPTPGKPPAQ 317
Query: 171 EDHQGVGLRGEEKPAGHR---TSPVAKIS---------PGATLPESR--------APDMS 210
+ G KP T P+A+ PG T P ++ A
Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377
Query: 211 PQRISNQLHGTIAVVRP-GSQACPADR-GPAN------GTPPPLPARSSPPSPAYERGLS 262
++ S++ G A+ +P G PA + GPA GTP PL + SPA G +
Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437
Query: 263 LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLH--LQSPHSSPLAPAAAPSDPRLQ 320
+ +A + P L + P P P P
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 321 DLKAREAEAWEEPTELLG----LPSALAGMQDLRLEGALHLLLAQQQLRARARAG-SVRP 375
+++ + + P + G P + + AQQ A+ A S +P
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 376 RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQD 435
Q G+ L V ++ P ++G + L P +A Q
Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP--LCNTTELLLHVPEKANFNTCTECQT 615
Query: 436 -----CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTR---- 486
C + L+E + G L+P + SP+P ++ P+T
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS---SPQPKLKTAPVTTTSAV 672
Query: 487 ---SPQALSNGTKGTRVPEQEEASTPMDPSRPLP--------GSQLSLSSPGSTEDEDTG 535
SPQ K P+Q+ + P +P +P P GS S + E +
Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAP-EPKKPPPLVKQPTLHGSP-SAKAKQPPEADSLS 730
Query: 536 RPLPPPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDET------DTPGSEVGLSSQ 588
+P PP P P + P D P+ K +++P +D + + D P S+V SQ
Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKV--QSQ 786
Query: 589 AEATTST---------------TGE-----------------------GPECICTQEHGQ 610
AE T+ TGE GP +
Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846
Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660
P +K++ + K S KP + PG A P+P SP
Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Score = 43.5 bits (101), Expect = 6e-04
Identities = 54/215 (25%), Positives = 77/215 (35%), Gaps = 30/215 (13%)
Query: 452 GQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPL---TRSPQALSNGTKGTRVPEQEEAST 508
G+D + G S+S +PP P+ T++PQ T ++P Q +AS
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ-----TDHAKLPLQRDASR 280
Query: 509 PMDPSRPLP-GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH----PEPSKA 563
P + G + S P P PP QP P P GH P P+K
Sbjct: 281 PQTKQADIVRGESVKPSLPS---------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331
Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTSTTGE--GPECICTQEHGQGPPRKRKRASE 621
+P PG+ V Q TT + GP Q+ G P + +
Sbjct: 332 PA-QPSGLTKPLAQQPGT-VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP----SSEQ 385
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656
PG KA +P + GP P + +P P
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420
Score = 42.0 bits (97), Expect = 0.002
Identities = 84/408 (20%), Positives = 135/408 (33%), Gaps = 42/408 (10%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-LHGTIAVVRPGSQACPADRGPA 239
+ P +TSP +P L ++ P P + LHG+ + + PA
Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733
Query: 240 NGTPPPLPARS-----SPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
P +P+ + P + + + L +S + + P +
Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793
Query: 295 PLSLHLQSPHSS--PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLR-L 351
PL P S P +P D + A +++ P G S G + + +
Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSSESKGQKQVDPV 849
Query: 352 EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPS----LPVGSDSEGPENEGTRAALA 407
+ AQ ++ + A + P+G PTP P+ +P S P+ + R +L
Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908
Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSP 467
++ +QP P Q T S GQ P P Q G +P
Sbjct: 909 LGSITDAPKSQPTTP---QETVTGKLFGFGASIFSQASNLISTAGQ--PGPHSQSGPGAP 963
Query: 468 AAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG 527
A +PPT GP + QA K +P ++E P Q
Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKS--IPVKKETKAPAAEKLEPKAEQAPTVKRT 1021
Query: 528 STEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE----PSKAEVL-RPES 570
TE +PPP L P+ P+K E +PES
Sbjct: 1022 ETE------------KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057
Score = 41.2 bits (95), Expect = 0.003
Identities = 119/569 (20%), Positives = 199/569 (34%), Gaps = 86/569 (15%)
Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEK 161
++E G K+ + K+E + PKP AK +G+ PP P P+ G ++
Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR--PTAGQTVPTPQQ 894
Query: 162 PPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISP-----GATLPESRAPDMS----PQ 212
P E++ +G + P T+P ++ GA++ + +S P
Sbjct: 895 SPKPQEQSRRFSLNLGSI-TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 213 RISNQLHGTIAVVRPGSQACPADRGP--ANGTPPPLPARSSP-----PSPAYERGLSLDS 265
S G P P +GP + G PP PA+S P +PA E+ L+
Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK---LEP 1010
Query: 266 FLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKA 324
+ T K P D L P L + SP + P ++ +
Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070
Query: 325 REAEAWEEPTELLGLPSALAGMQDLRLEGALH---LLLAQQQLRARARAGSVRPRGQPTP 381
++ + TE L G + L Q Q + G +R
Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130
Query: 382 GEMLPSLPVGSDSEGPEN-------------------------EGTRAALAAAGLSGGRH 416
G +PV ++S + E + L+ +
Sbjct: 1131 GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190
Query: 417 T-QPAGPGRAQRTEAAATQDCALDKPLD-----LSEWGRARGQDTP------KPAGQHGS 464
T Q + ++ +A+A Q+ KPL + E + R ++ KP +
Sbjct: 1191 TDQKQEESKLEKDKASALQE---KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247
Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ--EEASTPMDPSRPLP-GSQL 521
L P A +A P Q L +S ++ RV + +E P LP G+
Sbjct: 1248 LLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQ 1304
Query: 522 SLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGS 581
SL ED+ T + + PQPP +P ++ E ++ E + + + P S
Sbjct: 1305 SLPK----EDDKTTKTIKE-QPQPPCTAKPDQVEPGKEKTEKE---DDKSDTSSSQQPKS 1356
Query: 582 EVGLSS---QAEATTSTTGEGPECICTQE 607
GLS ++ +S+ GE P I T E
Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385
Score = 35.0 bits (79), Expect = 0.22
Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 25/140 (17%)
Query: 500 VPEQEEASTPMDPS-----RPLPGSQLSLSSPG-------------STEDEDTGRPLPPP 541
+P +E+ ST S + P SQL SP S+ + + +P PPP
Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409
Query: 542 HPQPPPHPQPPDLDGHPEP---SKAEVLRPESD----ELDETDTPGSEVGLSSQAEATTS 594
P PPP P PP P P S + P+ T TP + + + A
Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469
Query: 595 TTGEGPECICTQEHGQGPPR 614
+ G ICT PP+
Sbjct: 2470 SNGLPVTRICTTAPPPVPPK 2489
Score = 29.6 bits (65), Expect = 9.3
Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 10/74 (13%)
Query: 190 SPVAKISPGATLPESRAP-------DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGT 242
SP++ +SPG L + P D+SPQ++ LH +A V P S +
Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKV---LHPDMAKVPPASPKTAKMMQRSMSD 3681
Query: 243 PPPLPARSSPPSPA 256
P PL + S A
Sbjct: 3682 PKPLSPTADESSRA 3695
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 61.6 bits (148), Expect = 2e-09
Identities = 137/558 (24%), Positives = 189/558 (33%), Gaps = 107/558 (19%)
Query: 142 DPPSPLL---LPSPGGWKAITEKPPGGH-EEAEEDHQGVGLRGEEK--------PAGHRT 189
+PPSP P P G K E PP G A + + V E+ P G T
Sbjct: 353 EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTT 412
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249
P + P AT A D + + + T V+ ++GP P P P R
Sbjct: 413 PP--ETDPAATSEAPSARDGPERSVPKEAEPTPPVLPD------EEKGPPG--PAPEPER 462
Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLA 309
+ P ERG + + PS AP SP + CL +RP + S PLA
Sbjct: 463 EAETEP--ERGAGTEPERIGTEPST----APAPSPPAPKSCLKHRPAAASEGPAASPPLA 516
Query: 310 PAAAPS-DPRLQDL----------KAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358
A +P +P L KA AEA E P A L GA
Sbjct: 517 AAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAE-RAAPERKAERGGAELRGAKKFS 575
Query: 359 LAQQQLRARARAGSVRP--------------------------RGQPTPGEMLPSLPVGS 392
++ RAR R G RP +G P P P P
Sbjct: 576 VS--SCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPG-PRKL 632
Query: 393 DSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK---PLDLS---- 445
GP++ G RAA + AG A PG + AA + D+ P+ L
Sbjct: 633 AERGPQDSGDRAA-SPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
Query: 446 --EWGRARGQDTPKPAGQHGSLSPAAAHTASPEP---PTQSGPLTRSPQALSNGTKGTRV 500
++ Q+ + + T P+ P + P R +A S+ KG
Sbjct: 692 SLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKAR 751
Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEP 560
P + +S P P +PL S PH PP P + + EP
Sbjct: 752 PPEPLSSKPPLPRKPLLQS------------------FTLPHQPAPPDAGPGEREPRKEP 793
Query: 561 SKAEVLRPESDELDETDTPGSEVGLSSQAEAT----TSTTGEGPECICTQEHGQGPPRKR 616
AE RP E P + G + + T T + + + + P R
Sbjct: 794 RTAE-KRPLRRGA-EKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGAR 851
Query: 617 KRASEPGDKASKKPSRGR 634
SEPG K +K P RG+
Sbjct: 852 TLKSEPG-KQAKVPERGQ 868
Score = 55.8 bits (133), Expect = 1e-07
Identities = 114/456 (25%), Positives = 154/456 (33%), Gaps = 45/456 (9%)
Query: 183 KPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVV---RP--GSQACPADRG 237
KP R+S + ++S A +P+ N+ + V RP G Q DRG
Sbjct: 231 KPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRG 290
Query: 238 PANGTPPPLPARSSPPSPAYERGLSL--DSFLRAS-RPSAMTHEAPKLSPKVDRLCLLNR 294
P G P PLP PP A R L S L AS + E P P L
Sbjct: 291 PEPGPPAPLP----PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES 346
Query: 295 PLSLHLQSPHSSPLAPAAAPSDPRLQDLKARE----AEAWEEPTELLGLPSALAGMQDLR 350
+L ++ P S P P D QD +A A A ++ E++ P +A
Sbjct: 347 APTLRVEPP-SPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTA 405
Query: 351 L-EGALHLLLAQQQLRARARAGSVRPRGQ-PTPGEMLPSLPVGSDSE----GPENEGTRA 404
+ EG + A + A S R + P E P+ PV D E GP E R
Sbjct: 406 IPEG--DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPERE 463
Query: 405 ALAAAGLSGGRHTQPAG--PGRAQRTEAAATQDCALDKPLDLSEWGRA----RGQDTPKP 458
A G + G P A A + C +P SE A ++P
Sbjct: 464 AETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPV 523
Query: 459 AGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTK---GTRVPEQEEASTPMDPSRP 515
GSL AA P+ P + +A G + ++ S +RP
Sbjct: 524 EPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP 583
Query: 516 LPGSQLSLSSPGSTEDEDTGR-PLPPPHPQPPPHPQPPDLDGHPEPSKAEV---LRPESD 571
PG L + +GR PL P DL G PEP A+ E
Sbjct: 584 RPGVSRPL-------ERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERG 636
Query: 572 ELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQE 607
D D S G + + G C QE
Sbjct: 637 PQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQE 672
Score = 39.3 bits (90), Expect = 0.012
Identities = 56/224 (25%), Positives = 81/224 (36%), Gaps = 53/224 (23%)
Query: 474 SPEPPTQSGPLTRS----PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGST 529
+P PP R+ AL+ + VP ++ +S P P P
Sbjct: 297 APLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP------------ 344
Query: 530 EDEDTGRPLPPPHPQPPPHPQPP--DLDGHPEPS--------KAE--------VLRPESD 571
E T R PP P+ PP+P P DG P+ KAE V P
Sbjct: 345 ESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPT 404
Query: 572 ELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQE---------------HGQGPPRKR 616
+ E DT E ++ +EA ++ +GPE +E G P +R
Sbjct: 405 AIPEGDTTPPETDPAATSEAPSAR--DGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER 462
Query: 617 KRASEPGDKASKKPSR-GRRKLTA-TEGPGSPRDAEDHSPSPNS 658
+ +EP A +P R G TA P +P+ H P+ S
Sbjct: 463 EAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAAS 506
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 59.3 bits (142), Expect = 1e-08
Identities = 100/517 (19%), Positives = 183/517 (35%), Gaps = 58/517 (11%)
Query: 180 GEEKPAGHRTSPVAKIS---------PGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQ 230
G +P G +P++ + PG +P+ + + +++ + + G+
Sbjct: 2134 GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193
Query: 231 ACPADRGPA------NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS- 283
P A + P P+P S +PA +L S + A+ +AM + +
Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPA----ANLASRIPAASAAAMNLASARTPA 2249
Query: 284 -PKVDRLCLLNRPLS---LHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGL 339
P L P + ++L SP ++ A +DPR A P L L
Sbjct: 2250 IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAL 2309
Query: 340 PSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPEN 399
+G A + + + +A A A V PR + ++ +
Sbjct: 2310 SLTGSGTPPT----AANYPSSSRTPQAPASANLVGPRSAHATAPV--NIAGSRTAAALAP 2363
Query: 400 EGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK-----PLDLSEWGRARGQD 454
+A A LSG T P P A + T LD+ P R +
Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423
Query: 455 TPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514
P P+ + G A + S PP Q P + P A S+ ++ +TP+ S+
Sbjct: 2424 APSPSSRMGQ-----APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ-----TTPVAGSQ 2473
Query: 515 PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELD 574
L ++ ++ S D + +P P +PP G +PS L+P +
Sbjct: 2474 SLSSGAVATTT-SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRS 2532
Query: 575 ETDTPGSEVGLSSQAEATTSTTGEGPECICTQ------------EHGQGPPRKRKRASEP 622
+ + S SS + +++S++ G ++ + P K A
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Query: 623 GDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
G P++ +R+ +++ S + S S +SS
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629
Score = 57.8 bits (138), Expect = 3e-08
Identities = 125/555 (22%), Positives = 191/555 (34%), Gaps = 73/555 (13%)
Query: 172 DHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAP-DMSPQRISNQLHGTIAVV----- 225
DHQ + P H S +A +L +R P MS ++ ++ A V
Sbjct: 2166 DHQRTSV-----PENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL 2220
Query: 226 RPGSQACPADRGPA---------NGTPPPLPAR---SSPPSPAYERGLSLDSFLRASRPS 273
R A A R PA + P +P + +PA ++L S A PS
Sbjct: 2221 RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS 2280
Query: 274 AMTHEAPKL--SPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA--------PSDPRLQDLK 323
A+ P+ +P V+ L P +L S S P AA P P +L
Sbjct: 2281 AVNLADPRTPTAPAVN-LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLV 2339
Query: 324 AREAEAWEEPTELLGLPSALA----GMQDLRLEGAL---HLLLAQQQLRARAR-AGSVRP 375
+ P + G +A A + R+ AL +L + L A R +G P
Sbjct: 2340 GPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSP 2399
Query: 376 ----RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP---GRAQRT 428
R + PS + P + L QP P + ++
Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459
Query: 429 EAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSL----SPAAAHTASPEPPTQSGPL 484
Q + LS A T AG H + +P H+ EPP +G
Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVAT---TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516
Query: 485 TRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH-- 542
S A K R +S+ S S S S S++ E + P+ P
Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576
Query: 543 ---PQPPPHPQPPDLDGHP-EPSKAE-VLRPESDELDETDTPGSEVGLSSQAEATTSTTG 597
P P P P+ +G P EP+ A+ R S + + S SS + +++S++
Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 598 EGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP-GSPRDA------- 649
+ P + +A P + KKP G R+ + P S RD+
Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQAL-PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP 2695
Query: 650 -EDHSPSPNSSPWEE 663
E PSP SP ++
Sbjct: 2696 VERRRPSPQPSPRDQ 2710
Score = 43.1 bits (100), Expect = 8e-04
Identities = 111/523 (21%), Positives = 171/523 (32%), Gaps = 74/523 (14%)
Query: 131 RPKPRAKEGTSDP----PSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAG 186
RP P + ++ P P+PLL GG P E + R P
Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408
Query: 187 HRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPL 246
P + S ES P P ++S A P + P P
Sbjct: 409 PEKLPQSSSS------ESSPPSPQPTKVSRH----------------ASSSPESPKPAPA 446
Query: 247 PAR-----SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQ 301
P SSP S G RA R + +H + + R S +
Sbjct: 447 PGSHREISSSPTSKNRSHG-------RAKRDKSHSHTPSRRMGRSRSPATAKRGRS-RSR 498
Query: 302 SPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQ 361
+P + + +P Q ++R A+ W P + + G Q
Sbjct: 499 TPTKRGHSRSRSP-----QWRRSRSAQRWGRSRS----PQRRGRSRSPQRPGWSRSRNTQ 549
Query: 362 QQLRAR-ARAGSVRPRGQPTPGEMLPSLPVG---SDSEGPENEGTRAALAAAGLSGGRHT 417
++ R+R AR G R T G P S S P +R+ S R
Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR-- 607
Query: 418 QPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEP 477
PA GR+ R+ A + P+ R+R + + +G+ S +PA +
Sbjct: 608 TPARRGRS-RSRTPARRRSRTRSPVRR----RSRSRSPARRSGRSRSRTPARRGRSRSRT 662
Query: 478 PTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR- 536
P + G A +G +R P + S P R S+ SL G + R
Sbjct: 663 PARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR-SLVRRGRSHSRTPQRR 721
Query: 537 ----PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEAT 592
+ + + PE K+ + S L +P S+ S+
Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL---SSPRSKA--KSRLSLR 776
Query: 593 TSTTGEGPECICTQEHGQGPPRK-RKRASEPGDKASKKPSRGR 634
S +G P C ++ Q PPR+ R +S+P K+ P R R
Sbjct: 777 RSLSGSSP---CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816
Score = 38.1 bits (87), Expect = 0.026
Identities = 120/589 (20%), Positives = 180/589 (30%), Gaps = 88/589 (14%)
Query: 131 RPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPG-----GHEEAEEDHQ----------- 174
+P ++ +S P SP P+PG + I+ P G + ++ H
Sbjct: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485
Query: 175 --GVGLRGEEKPA-----GH--------RTSPVAKISPGATLPESRAPDMSPQRI----- 214
RG + GH R S A+ + P+ R SPQR
Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545
Query: 215 -SNQLHGTIAVVRPGSQ--ACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASR 271
+ Q G R G PA RG + P RS +PA R S R SR
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605
Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWE 331
S R R S + S + ++R
Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665
Query: 332 EPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVG 391
P+ +G R ++ R R+R+ S+ RG+ G
Sbjct: 666 RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725
Query: 392 SDSE----------------GPENEGTR-AALAAAGLSGGRH--------------TQPA 420
S SE PE + +R ++ + LS R + P
Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785
Query: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480
++Q + + K + R+R +P P + + S + ++SP P +
Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845
Query: 481 SGPLTR-----SPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535
SG R SPQA R E + P SR S SSP +
Sbjct: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905
Query: 536 RPLPPPHPQPPP------HPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLS--- 586
R P P P P+ G PS + V + + +P S V
Sbjct: 906 RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965
Query: 587 --SQAEATTSTTGEGPECICTQEHGQ--GPPRKRKRASEPGDKASKKPS 631
S + +++ T PE Q H P K K + PG S S
Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014
Score = 37.7 bits (86), Expect = 0.034
Identities = 54/268 (20%), Positives = 89/268 (33%), Gaps = 22/268 (8%)
Query: 391 GSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRA--QRTEAAATQDCALDKPLDLSEWG 448
GS+S + R L SG P + +R+E+ ++ D L +
Sbjct: 1518 GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ-- 1575
Query: 449 RARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508
R+R +P+ LSP + + S S + P+A G+ + +A
Sbjct: 1576 RSRSGSSPE-VDSKSRLSPRRSRSGS------SPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628
Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRP 568
P R LP S SS G P+ PP + P R
Sbjct: 1629 P----RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684
Query: 569 ESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASK 628
+P E+ ++ + + PE + PPR R+ S + ++
Sbjct: 1685 PPRRRSSRSSP--ELTRKARLSRRSRSASSSPET-----RSRTPPRHRRSPSVSSPEPAE 1737
Query: 629 KPSRGRRKLTATEGPGSPRDAEDHSPSP 656
K RR+ +A+ SPSP
Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSP 1765
Score = 37.7 bits (86), Expect = 0.034
Identities = 103/514 (20%), Positives = 166/514 (32%), Gaps = 92/514 (17%)
Query: 139 GTSDPPSPLLLPSPGGW-----KAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193
G+ PP+ PS A P H A + G PA ++ +A
Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMA 2372
Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP 253
GA L R P + +R+S + T PPL R+
Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGR------------------------TSPPLLDRARSR 2408
Query: 254 SPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA 313
+P S + RA PS+ +AP S L P +SP P+A
Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQS--------LLPPAQDQPRSP-----VPSAF 2455
Query: 314 PSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSV 373
R L+ + +AG Q L GA+ A A G +
Sbjct: 2456 SDQSRC----------------LIAQTTPVAGSQSLS-SGAV----ATTTSSAGDHNGML 2494
Query: 374 RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433
P PG +P VG E P + G + A A L + + + + + ++++
Sbjct: 2495 ---SVPAPG--VPHSDVG---EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546
Query: 434 QDCALDKPLDLSEWGRARGQDTPKPAG----QHGSLSPAAAHTASPEPPTQSGPLTRSPQ 489
+ S + G P + S +PA P + P R +
Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRR 2606
Query: 490 ALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP 549
+ S+ + + +S+ S S S SS S+ +P P P+P
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Query: 550 QPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHG 609
+PP P ++ R D L ++ + S E + P ++
Sbjct: 2667 KPP-----PGERRSRSPRKPIDSLRDSRSLS-----YSPVERRRPSPQPSP-----RDQQ 2711
Query: 610 QGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643
+ R + GD S+ PS RR+ T + P
Sbjct: 2712 SSSSERGSRRGQRGD--SRSPSHKRRRETPSPRP 2743
Score = 35.8 bits (81), Expect = 0.13
Identities = 56/259 (21%), Positives = 88/259 (33%), Gaps = 16/259 (6%)
Query: 417 TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE 476
T P+ + Q T ++ L P + + G + Q P +P+ ++S
Sbjct: 1365 TDPSLDMKEQSTRSSGHSSSELS-PDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423
Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536
P L R+P S + + + S PG + +P E
Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483
Query: 537 PLPPPHPQPPP----HPQPPDLDGHPEPSKAEVLRPES--DELDETDTP-------GSEV 583
P P PQ P P P+L+ + E ES D+ TP GS
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA--SEPGDKASKKPSRGRRKLTATE 641
L + A+ E ++ + P R+R R+ S D S+ R R ++ E
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603
Query: 642 GPGSPRDAEDHSPSPNSSP 660
PR A +SSP
Sbjct: 1604 VKDKPRAAPRAQSGSDSSP 1622
Score = 32.7 bits (73), Expect = 1.1
Identities = 74/322 (22%), Positives = 111/322 (34%), Gaps = 60/322 (18%)
Query: 365 RARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGR 424
R+R+R+ + + G PS G EG A + G + + +P+ P
Sbjct: 276 RSRSRSAAAKTHTTALAGRS-PSPASGRRGEGD------APFSEPGTTSTQ--RPSSPET 326
Query: 425 AQRTEAAATQDCALDKPL----------DLSEWGRARGQDTPKPAGQHG-SLSPAAAHTA 473
A + ++ +D DK + S G TP A +HG S P A
Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386
Query: 474 SPEP--------PTQSGPLTRSPQALSNGTKGTRVPEQEE--------ASTPMDPS-RPL 516
S EP PT+ +SP+ L + P + +S+P P P
Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446
Query: 517 PGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDET 576
PGS +SS ++++ GR + H P S A R S T
Sbjct: 447 PGSHREISSSPTSKNRSHGRA-----KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501
Query: 577 DTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQG-PPRKRKRASEPGDKASKKPSRGRR 635
G S Q + S Q G+ P++R R+ P ++P R
Sbjct: 502 KR-GHSRSRSPQWRRSRS----------AQRWGRSRSPQRRGRSRSP-----QRPGWSRS 545
Query: 636 KLTATEGPG-SPRDAEDHSPSP 656
+ T G S R HS SP
Sbjct: 546 RNTQRRGRSRSARRGRSHSRSP 567
Score = 32.0 bits (71), Expect = 1.9
Identities = 120/641 (18%), Positives = 209/641 (32%), Gaps = 119/641 (18%)
Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVL-GDRPKPRAKEGTS 141
+R Q+ S+ +++ I + L K + R L G P P+ K T
Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP 793
Query: 142 DPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGA-- 199
S P KA + PP + + + + +SP K+ G
Sbjct: 794 PRRSRSGSSQP---KAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850
Query: 200 -----TLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254
T P++ ++PQR S P ++ R +G+ PP S+PP
Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSP----DPELKSRTPSRHSCSGSSPPRVKSSTPPR 906
Query: 255 PAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP----------- 303
+ R S ++A + SP R+ P SP
Sbjct: 907 QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR 966
Query: 304 ----------------------HSSPLAP-----AAAPSDPRLQDLKAREAEAWEEPTEL 336
HS ++P A P P L K+ + + + +
Sbjct: 967 YSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV 1026
Query: 337 LGLPSAL---AGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSD 393
P +L AG++ G + ++ QL+ ++ Q +P SD
Sbjct: 1027 QSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS---------QTSPDHR-------SD 1070
Query: 394 SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQ 453
+ PE + + + L T P G GR++ ++ + A P+ + RG+
Sbjct: 1071 TSSPEVRQSHS--ESPSLQSKSQTSPKG-GRSR--SSSPVTELASRSPI-----RQDRGE 1120
Query: 454 DTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513
+ P + G +SP + S + S P S L T +++ A P + +
Sbjct: 1121 FSASPMLKSG-MSPEQSRFQS---DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176
Query: 514 RPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDE- 572
P Q SP +D + + PP + PE + P S +
Sbjct: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPR-ERSGAGSSPETKEQNSALPTSSQD 1235
Query: 573 ------LDETDTPGSEV--GLSSQ-AEATTSTTGEGPECICTQEHGQGPPRKRKRASEPG 623
+++++ P ++ LSS+ E +TS PE P
Sbjct: 1236 EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEV----------------EERPA 1279
Query: 624 DKASKKPSRGRRKLTATEGP------GSPRDAEDHSPSPNS 658
+ S+ + L A E P G P + +H NS
Sbjct: 1280 VSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS 1320
>gi|188536004 zinc finger protein 469 [Homo sapiens]
Length = 3925
Score = 58.5 bits (140), Expect = 2e-08
Identities = 122/526 (23%), Positives = 178/526 (33%), Gaps = 121/526 (23%)
Query: 130 DRPKPRAKEGT-SDPPSPLLL--------PSPGGWKAITEKP--PGGHEEAEEDHQGVGL 178
DRP PR S+ P LL + GW E+P P H +
Sbjct: 3461 DRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP----------I 3510
Query: 179 RGEEKPAGHRTSPVAKISP-GATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRG 237
RG E P+ H+ P +SP A L + R L G A+ RP ++A P G
Sbjct: 3511 RGCELPSNHQECPPPSLSPFPAALADGRG--------DCALDG--ALERPENEASPGSPG 3560
Query: 238 PANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLS 297
P LP +S P P RG + + + + + +P C +
Sbjct: 3561 PL--LQQALPLGASLPRPG-ARGQDAEG-----KRAPLVFSGKRRAPGARGRCAPDHFQE 3612
Query: 298 LHL----QSPHSSPLAPAAAP---------SDPRLQDLKAREAEAWEEPTELLGLPSALA 344
HL + SS + P + P +++ A P++ L P
Sbjct: 3613 DHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP---- 3668
Query: 345 GMQDLRLEGALHLLLAQQQLRARARAGSVRPR--GQPTPGEMLPSLPVGSDSEGPENEGT 402
+ R GS+ P + T M P+ P GP ++G+
Sbjct: 3669 -------------------VHPRKAVGSLAPGELARGTENGMKPATPKAKP--GPSSQGS 3707
Query: 403 RAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDT-----PK 457
+ GG QPA G+ Q A + E AR Q P+
Sbjct: 3708 GSPRPGTKTGGGSQPQPAS-GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPR 3766
Query: 458 PAGQ---HGSLSPAAAHTASPEP-------PTQSGPLTRSPQALSNGTKGTRVPEQEEAS 507
AG+ HGSL P +S + P +S + +A S K R P ++
Sbjct: 3767 EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATP 3826
Query: 508 TPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ---PPPHPQPPDLDGHPEPSKAE 564
+ + P++P P SQ +P PPP Q P H Q D G P
Sbjct: 3827 SRVLPTKPKPNSQ--------------NKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872
Query: 565 VLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610
+LRP G+ V + AE T T E + +Q GQ
Sbjct: 3873 LLRPPK--------RGTAVHGAEPAEPHTHRTAEAQSDLLSQLFGQ 3910
Score = 54.3 bits (129), Expect = 4e-07
Identities = 143/555 (25%), Positives = 191/555 (34%), Gaps = 106/555 (19%)
Query: 112 KEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKP--PGGHEEA 169
+ E + EE+ R + P + P + P+PG ++ P PG + E
Sbjct: 168 RTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEY 227
Query: 170 EEDHQGVGLRGEEK--PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-----LHGTI 222
+ E P + P A+ P +P+ P SP+ +S Q LHG
Sbjct: 228 QASGADSWPPAAENSFPGANFGVPPAEPEP---IPKGSRPGGSPRGVSFQFPFPALHGAS 284
Query: 223 AVVRPGSQACPA-DRGP---------------ANGTPP--PLPARSSP-PSPAYER---G 260
P A A GP A GT P PLP + +P P P Y+ G
Sbjct: 285 TKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGG 344
Query: 261 LSLDSFLRASRPS-AMTHEAPKLSPKVDRL------CLLNRPLSLH-----LQSPHSS-- 306
L+ S L + S H AP+ P D L L RP S + P SS
Sbjct: 345 LNRHSDLSGALSSPGAAHSAPR--PFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP 402
Query: 307 --------------------PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSA--LA 344
P AAP P AR + W+ P LA
Sbjct: 403 QRHFPGQAYRASGVDTSPGPPDTELAAPGPP-----PARLPQLWDPTAAPYPTPPGGPLA 457
Query: 345 GMQDLRLEG----ALHLLLAQQQLRARARAGSVRPRGQPTPG--EMLPSLPVGSDSEGPE 398
+ + G L L Q A V P +P+P EML LP + GPE
Sbjct: 458 ATRSMFFNGQPSPGQRLCLPQS---APLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPE 512
Query: 399 NEG-TRAALAAAGLSGG-RHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTP 456
+G ++ AL AG + G R PA + A T + D +G A+ Q +P
Sbjct: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572
Query: 457 KPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514
HG SL P ASP P T + + T + P + P
Sbjct: 573 -----HGTPSLPPPRVVGASPSESPLPSPATNT----AGSTCSSLSPMSSSPANPSSEES 623
Query: 515 PLPGSQ-LSLSSPGSTEDEDTGRPLPPPHPQP--PPHPQPPDLDGHPEPSKAEVLRPESD 571
LPG S T ++TG P P P P P H QP P P+
Sbjct: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQ 683
Query: 572 ELDETDTP--GSEVG 584
L+ET P G EVG
Sbjct: 684 CLEETPFPHEGPEVG 698
Score = 45.8 bits (107), Expect = 1e-04
Identities = 131/535 (24%), Positives = 183/535 (34%), Gaps = 89/535 (16%)
Query: 151 SPGGWKAITEKPPGGHEEAEEDHQGVGLRGE-EKPAGHRTS----PVAKISPGATLPESR 205
SPGG + T GH+ E GL G+ EK G T+ P +SPG T +
Sbjct: 1930 SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHAS 1989
Query: 206 APDMSPQRISNQLHGTIAVVR-PGSQACPADRGPANGTPPPLPARSSPPSPAYER-GLSL 263
++ G + + + GS+A + + A TP SPPSP E L+L
Sbjct: 1990 VNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTP-------SPPSPNRESLALAL 2042
Query: 264 DSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLK 323
+ S T E SP LN+PL SP APS L
Sbjct: 2043 TAAHSRSGSEGRTPERAS-SPG------LNKPLLATGDSP---------APSVGDLAACA 2086
Query: 324 AREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGE 383
A P L LP R +G L QL A S R P P +
Sbjct: 2087 PSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLG-----GQLPA-----SPSCRDPPGPQQ 2136
Query: 384 MLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLD 443
+L P + E E +G +A G P P + T C P +
Sbjct: 2137 LLACSPAWAPLE--EADGVQATTDT-----GAEDSPVAP------PSLTTSPC---DPKE 2180
Query: 444 LSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ 503
+G+ +P +A T + T R P+ ++ ++ E
Sbjct: 2181 ALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPE----DSRKEKLWES 2236
Query: 504 EEASTPMDPSRPLPGS--------QLSLSSPGSTEDEDTGRPLPPPHPQ---PPPHPQPP 552
+T S PL G+ LSS + ++ GR LP P PQ PPH P
Sbjct: 2237 PGRAT----SPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPD 2292
Query: 553 DLD-GHPEPSKAEVLRPESDELDETDTPGSE------VGLSSQA--EATTSTTGEGPECI 603
+ GH S + R E +E G S A E T+ + PE
Sbjct: 2293 RMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP 2352
Query: 604 CTQEHGQGPPRKRKRASEP----GDKASKKPSRGRRKLTATEGPGSPRDAEDHSP 654
T E G+ K R + P G + PS ++ P S R+A +P
Sbjct: 2353 GTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF-QSDSPQSHRNASHQTP 2406
Score = 43.9 bits (102), Expect = 5e-04
Identities = 107/484 (22%), Positives = 149/484 (30%), Gaps = 113/484 (23%)
Query: 167 EEAEEDHQGVGLRGEEKPAGHR---TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIA 223
+ E D + + +E+P+G R + K G T PES+AP P +
Sbjct: 856 DNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT-PESKAPPPLPAATPDP-----Q 909
Query: 224 VVRPGSQACPADRGPANGTPPPLPARSSPPSPAYE--RGLSLDSF--------------- 266
RPG + CPA P + P + PS + RG L F
Sbjct: 910 TPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGS 969
Query: 267 --------LRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS----SPLAPAAAP 314
LR R + P RP Q+P S +P P AA
Sbjct: 970 GGGGRASGLRPRRNDGLGERPPP------------RPRRPRTQAPGSRADPAPRVPRAAA 1017
Query: 315 SDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVR 374
+ + R ++P + A E L ++ + +LR A
Sbjct: 1018 LPEETRSSRRRRLPPRKDPRKRKARGGAWGK------ELILKIVQQKNRLREYDFASESE 1071
Query: 375 PRGQPTP-----------GEMLPSLPVGSDSEGPENEGTR-AALAAAGLSG--------- 413
QP P GE + + E + R AA AG G
Sbjct: 1072 EDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG 1131
Query: 414 ------GRHTQPAGPGRAQRTEAAATQ---------DCALDKPLDLSEWGRARGQDTPKP 458
GR Q GP R+ T AAA + A PL + + P
Sbjct: 1132 GSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191
Query: 459 AGQHGSLSPAAAHTASPE-----------PPTQSGPLTRSPQAL-------SNGTKGTRV 500
+ P A ++P+ P +G + SP L S GT
Sbjct: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPK 1251
Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQP---PDLDGH 557
P A+T S P PG L PG T+ + PP QP P P
Sbjct: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTAC 1311
Query: 558 PEPS 561
P+PS
Sbjct: 1312 PKPS 1315
Score = 41.2 bits (95), Expect = 0.003
Identities = 122/535 (22%), Positives = 165/535 (30%), Gaps = 111/535 (20%)
Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTP 243
P T P SP S PD+ R L+G+++ R A P
Sbjct: 1406 PGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF------ACADP 1459
Query: 244 PPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP 303
P S PP P++ L P +H KV L P
Sbjct: 1460 PQKTVPSDPPYPSF-------LLLEEVSPMLPSHFPDLSGGKV-----------LSKTCP 1501
Query: 304 HSSPLAPAAAPSDP---------RLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354
+ P AAPS P + L E E + TE L S L +D R
Sbjct: 1502 PERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTE---LESQLQRSKDTR-GAP 1557
Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE-------GPENEGTRAALA 407
L A+ R G+ P + T +P S ++ EG +A+A
Sbjct: 1558 RELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVA 1617
Query: 408 AA----GLSGGRHTQPAG--PGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQ 461
G GG PA PG A A +D P Q K
Sbjct: 1618 TVEAVQGRPGGTWPCPASFHPGHAALL-PCAQEDLVSGAPFS-PRGANFHFQPVQKAGAS 1675
Query: 462 HGSLSPAAAHT------ASPEPPTQSGP-LTRSPQALSNGTKGTRVPEQEEASTPM---D 511
L A + PEP Q GP L A + + P+ +EA++ D
Sbjct: 1676 KTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESED 1735
Query: 512 PSRPLPGSQLS--LSSPGSTEDEDTGRPLPPPHPQPPPHPQP---------PDLD----- 555
R LP Q L PG+ + G P P P H P P LD
Sbjct: 1736 SLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPF 1795
Query: 556 ---------GHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEG------- 599
GH L P + PG E + A A++ T G
Sbjct: 1796 GASPSHAAQGHSAGRAGGHLHPTAGR------PGFEGNEFAPAGASSLTAPRGREAWLVP 1849
Query: 600 ---PECIC-------TQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLT-ATEGP 643
P C+ +Q+ PP ++ + PG SK G ++LT A + P
Sbjct: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSP 1904
Score = 35.0 bits (79), Expect = 0.22
Identities = 139/600 (23%), Positives = 180/600 (30%), Gaps = 147/600 (24%)
Query: 146 PLLLPSPGGWKAITEKP-PGGHEEAEEDHQG-VGLRG------EEKPA------------ 185
P PSP G + ++ P P G E + QG +G G E+ PA
Sbjct: 489 PTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALF 548
Query: 186 --GHRTSPVAK----------ISPGAT--LPESRAPDMSPQRISNQLHGTIAVVRPGSQA 231
T P A+ +SP T LP R SP T S
Sbjct: 549 TYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSL 608
Query: 232 CPADRGPANGT-----------------PPPLPARSSPPSPAYERGLSLDSFLRASRPSA 274
P PAN + PP P + P P+ E SL + + A
Sbjct: 609 SPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKA 668
Query: 275 MTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSP-LAPAAAPSDPRLQDLKAREAEAWEEP 333
A L + CL P PH P + PR P
Sbjct: 669 FPFPADGLGAEGAFQCLEETPF------PHEGPEVGRGGLQGFPRAPP---------PYP 713
Query: 334 TELLGLPSALAGMQDLRLE--------GALHLLLAQQQ----LRARARAGSVRPRGQPTP 381
T L SA D+ L +L LA +Q L ARA+ G R G P
Sbjct: 714 THHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPG- 772
Query: 382 GEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKP 441
LPS P + G LS + AG +A+ D P
Sbjct: 773 ---LPSPPAAPRVPADAHAGL--------LSHAKTFLLAGDAQAE----------GKDDP 811
Query: 442 LDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVP 501
L P PA A + E + +P+ S+ V
Sbjct: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFID---VF 868
Query: 502 EQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPS 561
EE S P PS P L S E PPP P P PQ P P+
Sbjct: 869 ADEEPSGPRGPSSGHP-----LKSKAGVTPESKA---PPPLPAATPDPQTPRPGDRGCPA 920
Query: 562 KAEVLRPESDEL----DETDTPGS-------------EVGLSSQAEATTSTTGEGPECIC 604
+ RP++ L E D P L S A S +G G
Sbjct: 921 RG---RPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGG----- 972
Query: 605 TQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET 664
G+ + +R G++ +P R R T+ PGS D P + P EET
Sbjct: 973 ----GRASGLRPRRNDGLGERPPPRPRRPR-----TQAPGSRADPAPRVPRAAALP-EET 1022
Score = 32.0 bits (71), Expect = 1.9
Identities = 99/404 (24%), Positives = 131/404 (32%), Gaps = 82/404 (20%)
Query: 168 EAEEDHQ----GVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIA 223
E+EED Q G G RG R P P+ P++ + Q G
Sbjct: 1069 ESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK------PRKAARQEAGGDG 1122
Query: 224 VV---------RPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSA 274
RPG P RGP+ AR P A
Sbjct: 1123 APANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCA------------------ 1164
Query: 275 MTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAA-APSDPRLQDLKAREAEAWEEP 333
+ P ++PK PL + + S P+ P + + + A E
Sbjct: 1165 ---DRPSVAPK--------DPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF 1213
Query: 334 TELL-GLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRG---QPTPGEMLPSLP 389
TE L P+A AG + + LL+ +Q +R G+ +P G P P+
Sbjct: 1214 TEALRSPPAACAG----EMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPG 1269
Query: 390 VGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGR 449
VGS GP GT+A +S PA A A KP LS
Sbjct: 1270 VGSLLGGP--GGTQAP-----VSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKIS 1322
Query: 450 ARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGP---LTRSPQALSNGTKGTRVPEQEEA 506
+ G D PAG + P A P S P L P+ L+ P+
Sbjct: 1323 SFGCD---PAG--FNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSAR 1377
Query: 507 STPMDPSRPL------PGS---QLSLSSPGSTEDEDTGRPLPPP 541
P S L GS QL S PG+ E E GR PP
Sbjct: 1378 DAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE-PGRAASPP 1420
Score = 30.0 bits (66), Expect = 7.1
Identities = 45/203 (22%), Positives = 71/203 (34%), Gaps = 18/203 (8%)
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKG---TRVPEQEEASTPMDPSRPLPGSQLSLSS 525
A+ + E P GP R + K T+ P ++E P +R G +
Sbjct: 1067 ASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD---GA 1123
Query: 526 PGSTEDEDTGRPLPPPHPQPPPHPQPPDL-----DGHPEPSKAEVLRPESDELDETDTPG 580
P + E+ RP P PQ + + +G P+ + + P+ T+T
Sbjct: 1124 PANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTET 1183
Query: 581 SE---VGLSSQAEATTSTTGE--GPECICTQEHGQGPPR--KRKRASEPGDKASKKPSRG 633
SE L EA T E P+ E + PP + + PG ++P
Sbjct: 1184 SEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPS 1243
Query: 634 RRKLTATEGPGSPRDAEDHSPSP 656
R + GS + H SP
Sbjct: 1244 RHDTGTPKPSGSLANTAPHGSSP 1266
Score = 30.0 bits (66), Expect = 7.1
Identities = 37/145 (25%), Positives = 54/145 (37%), Gaps = 20/145 (13%)
Query: 456 PKPAGQHGSLSPAAAHTASP-EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514
P P G SPAA P EP Q + P+ S+ G P P ++
Sbjct: 2469 PHP-GAPAEPSPAALPAQQPLEPLAQK---CQPPRKKSHRVSGKERPNHSRGD-PSHVTQ 2523
Query: 515 PLP--GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDE 572
P P GS+ L +PGS + P P H + P P+ ++ + L P+ E
Sbjct: 2524 PPPAQGSKEVLRAPGSPHSQQLHPPSPTEH---EVDVKTPASKPRPDQAREDELHPKQAE 2580
Query: 573 LDE---------TDTPGSEVGLSSQ 588
E D+P G S++
Sbjct: 2581 KREGRRWRREPTVDSPSHSEGKSNK 2605
>gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo
sapiens]
Length = 2462
Score = 57.8 bits (138), Expect = 3e-08
Identities = 50/231 (21%), Positives = 88/231 (38%), Gaps = 17/231 (7%)
Query: 424 RAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGP 483
+ ++ AAA+++ A ++ E + +G + A T + T+S P
Sbjct: 682 KKKKAPAAASEEAAFPPVVEDEE------MEASGVSGNEEEMVEEAEATVNNSSDTESIP 735
Query: 484 LTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHP 543
+ A G G + P A P P + + + E TG P PP P
Sbjct: 736 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP--P 793
Query: 544 QPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECI 603
PP PP + E + P +E +E P +E + T E +
Sbjct: 794 APPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE-----ELAVDTGKAEEPVKSE 848
Query: 604 CTQEHGQGPPR----KRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAE 650
CT+E +GP + + A+ G ++K G + T + G+P+D++
Sbjct: 849 CTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 899
Score = 40.0 bits (92), Expect = 0.007
Identities = 121/565 (21%), Positives = 181/565 (32%), Gaps = 109/565 (19%)
Query: 28 ELNSERCRDAQRIEELFS-----KNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQEL 82
E NSE Q+ EL S + E+ +T K+ L LE+ R + ++ +
Sbjct: 589 EANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGL--LEHGRNWSAIARMVGSKTV 646
Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKE---- 138
++ + F QNL I + +++ KE N K++ + P E
Sbjct: 647 SQCKNFYFNYKKRQNLDEI-LQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEM 705
Query: 139 ---GTSDPPSPLLLPSPG--GWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193
G S ++ + + TE P H EA +D G G + PA
Sbjct: 706 EASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKD---TGQNGPKPPA-------- 754
Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP 253
+ GA P P P+ I T PA TPPP P S P
Sbjct: 755 --TLGADGPPPGPPTPPPEDIPAPTEPT-----------PASEATGAPTPPPAPPSPSAP 801
Query: 254 SPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA 313
P + + A+ P E K P + L + + P S A
Sbjct: 802 PPVVPKEEKEEE--TAAAPPVEEGEEQK-PPAAEELAVDTG----KAEEPVKSECTEEAE 854
Query: 314 PSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSV 373
+ +D +A EA A EGAL A+++ RA +
Sbjct: 855 EGPAKGKDAEAAEATA----------------------EGALK---AEKKEGGSGRATTA 889
Query: 374 RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433
+ G P + + E + R L P G RA
Sbjct: 890 KSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL-----LTPTGDPRA-------- 936
Query: 434 QDCALDKPLDLSEWGRARG-----QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSP 488
+ + KPLDL + + Q T +P +P PP P + +P
Sbjct: 937 -NASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP 995
Query: 489 QALSNGTKG----TRVPEQEEASTPM-DPSRPLPGSQLSLSSPGSTEDEDTGRPLP-PPH 542
Q + +G P +EA P+ P+ +L PG +G P P PP
Sbjct: 996 QQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL----PGDPPCWTSGLPFPVPPR 1051
Query: 543 PQPPPHPQPPDLD-------GHPEP 560
P PD GHP P
Sbjct: 1052 EVIKASPHAPDPSAFSYAPPGHPLP 1076
Score = 34.7 bits (78), Expect = 0.29
Identities = 67/319 (21%), Positives = 99/319 (31%), Gaps = 77/319 (24%)
Query: 377 GQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDC 436
G PTP PS P P+ E AA + G +P + ++
Sbjct: 787 GAPTPPPAPPS-PSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPA-AEELAVDTGKAEEP 844
Query: 437 ALDKPLDLSEWGRARGQDTP----------KPAGQHGSLSPAAAHTASPEPPTQSGPLTR 486
+ + +E G A+G+D K + G A +S P T
Sbjct: 845 VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 904
Query: 487 SPQALSN---GTKGTRVPEQEEASTPM-------DPSRPLPGSQLSLSSPGSTEDEDTGR 536
S + G K + + TP P +PL QL + + T
Sbjct: 905 SADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKV 964
Query: 537 PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTT 596
PP P P PP P + L+PESD
Sbjct: 965 HEPPREDAAPTKPAPP------APPPPQNLQPESD------------------------- 993
Query: 597 GEGPECICTQEHGQGPPRKRKRASEPGDKASKKP------SRGRRKLTA-----TEG--- 642
Q+ G P K + + P DK ++KP + +KL T G
Sbjct: 994 -------APQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPF 1046
Query: 643 PGSPRD---AEDHSPSPNS 658
P PR+ A H+P P++
Sbjct: 1047 PVPPREVIKASPHAPDPSA 1065
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/285 (19%), Positives = 89/285 (31%), Gaps = 38/285 (13%)
Query: 375 PRGQPTPGEMLPSLPVGSDSEG-PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433
P G PTP P + + +E P +E T A P P + E AA
Sbjct: 762 PPGPPTP----PPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA 817
Query: 434 QDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSN 493
P++ G++ PA + A T E P +S + + +
Sbjct: 818 P------PVE-------EGEEQKPPAAEE-----LAVDTGKAEEPVKSECTEEAEEGPAK 859
Query: 494 GTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPD 553
G E + + G + S G+ +D D+ +
Sbjct: 860 GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC-----------SADE 908
Query: 554 LDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATT--STTGEGPECICTQEHGQG 611
+D K +L P L T P + + P T+ H
Sbjct: 909 VDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHE-- 966
Query: 612 PPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656
PPR+ ++P A P + + A + PGS + SP+P
Sbjct: 967 PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAP 1011
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 57.0 bits (136), Expect = 5e-08
Identities = 122/503 (24%), Positives = 185/503 (36%), Gaps = 76/503 (15%)
Query: 204 SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSL 263
S AP Q Q+ ++A +Q+ PA GPA T L + PPS A +
Sbjct: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTV--LQGVTLPPS-AVAMLNTP 599
Query: 264 DSFLRASRPSAMTHEAPKL---SPKVDRLCLLNRPLSLHLQSPHSS--PLAP---AAAPS 315
D ++ + P+A T EA + P ++ PL L LQ P + P AP AAAP
Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP- 658
Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARA----- 370
P+ + A +LG P + A + + +L + L Q++ + A
Sbjct: 659 -PQATTPQPSPGLASSPEKIVLGQPPS-ATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716
Query: 371 ---GSVRPRGQPTPGEMLPSLPV----GSDSEGPENEGTRAAL----AAAGLSG-GRHTQ 418
SV P + P+ PV G + P+++ + A AAA L G G +
Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSS 776
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE-- 476
P+ P +A ++ +P +R Q +P + L P A P
Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPP---SRPQSVSRPPSEP-PLHPCPPPQAPPTLP 832
Query: 477 -----------PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSS 525
PP S P +P + P+ + P+ P+ LP S S +
Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLR----PQSQPPEGPLPPAPHLPPSSTSSAV 888
Query: 526 PGSTEDEDTGRPLPPPHPQ------PP---PHPQ---PPDLDGHPEPSKAEVLRPESDEL 573
S+E T LP P P PP PH PP L PEP+ P + ++
Sbjct: 889 ASSSE---TSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQM 945
Query: 574 DETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRG 633
T P Q +A + P I Q G P + ++ G S S
Sbjct: 946 VTTPFPA-----LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAAS-- 998
Query: 634 RRKLTATEGPGSPRDAEDHSPSP 656
L + + P A H+P+P
Sbjct: 999 --VLVSGQAPSGTPTAPSHAPAP 1019
Score = 42.4 bits (98), Expect = 0.001
Identities = 80/350 (22%), Positives = 120/350 (34%), Gaps = 36/350 (10%)
Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWE 331
P+ T AP P L++P+S+HL + SS + PA P A A +
Sbjct: 428 PATTTGAAPPQPPGA-----LSKPMSVHLLNQGSSIVIPAQHML-PGQNQFLLPGAPAVQ 481
Query: 332 EPTELLGLPSALAGMQDLRLEGALHL--------LLAQQQLRARARAGSV-RPRGQPTPG 382
P +L LP+ + G + A H +L Q L G V P
Sbjct: 482 LPQQLSALPANVGG--QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539
Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCAL---- 438
+L + P+ P +LAA L PAGP + A+
Sbjct: 540 HILSAAPIQVGQ--PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597
Query: 439 --DKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASP----EPPTQSGPLTRSPQALS 492
D + + A G+ P Q +P A T P +P Q P +PQA +
Sbjct: 598 TPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAA 657
Query: 493 NGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552
T P AS+ P + + G S + + LP Q P + P
Sbjct: 658 PPQATTPQPSPGLASS---PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714
Query: 553 DLDGHPEPSKAEVLRPESDELDETDTPGSE-VGLSSQAEATTSTTGEGPE 601
L P+ V P + TP ++ GL QA + ++ P+
Sbjct: 715 HLS---VPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 56.2 bits (134), Expect = 9e-08
Identities = 133/569 (23%), Positives = 199/569 (34%), Gaps = 120/569 (21%)
Query: 135 RAKEGTSDPPSPLLLPSPGGWKAITEKPPGG--HEEA------EEDHQGVGLRGEEKPAG 186
R EG+ P+PL P+ +++PP G H + ++ QG+G PA
Sbjct: 519 RLLEGSLGEPTPLPPPT-------SQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPA- 570
Query: 187 HRTSPVA-KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPP 245
+ SP++ K SP LP +P P R S P S R P P P
Sbjct: 571 -KASPLSTKASP---LPSKASPQAKPLRASEPSK------TPSSVQEKKTRVPTKAEPMP 620
Query: 246 LPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS 305
P + P+PA + + S +R + P+ +A +PK +
Sbjct: 621 KPPPETTPTPATPK---VKSGVRRAEPATPVVKAVPEAPKGGEA-----------EDLVG 666
Query: 306 SPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLR 365
P + A+ S L D +E+ G+ QQ++
Sbjct: 667 KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGV--------------------VQQEVE 706
Query: 366 ARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQP--AGPG 423
AG P P+P E+ VGS R L A GL+ ++P +G G
Sbjct: 707 QLDSAGVTGPH-PPSPSEIHK---VGSSM--------RPLLQAQGLAPSERSKPLSSGTG 754
Query: 424 RAQR--------TEAAATQDCALDKPL----DLSEWGRARGQ-DTPKPAGQHGSL----- 465
Q+ T A D L+ L D +EW R R Q DT + + GS
Sbjct: 755 EEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDY 814
Query: 466 ----SPAAAHTASPEPPTQSGPLTRSP----QALSNGTKGTRVPEQEEASTPMDPSRPLP 517
S P+PP ++ LT Q L + + E + A+
Sbjct: 815 VEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTAT---------- 864
Query: 518 GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD 577
S L+ G+ + G P P P P P P H + E L PE + TD
Sbjct: 865 -SGRGLAKHGTQK----GGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATD 919
Query: 578 TPGS-EVGLSSQAEATTSTTGE-GPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRR 635
G+ + GL ++TG G E Q G P R+ E R R
Sbjct: 920 GSGTLQGGLRRFKTIELNSTGSYGHELDLGQ--GPDPSLDREPELEMESLTGSPEDRSRG 977
Query: 636 KLTATEGPGSPRDAEDHSPSPNSSPWEET 664
+ ++T +P SP+ SS E++
Sbjct: 978 EHSSTLPASTPSYTSGTSPTSLSSLEEDS 1006
Score = 44.3 bits (103), Expect = 4e-04
Identities = 134/608 (22%), Positives = 205/608 (33%), Gaps = 128/608 (21%)
Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPG 164
++E L+EE E L+E+ K V R + A++ D + ++ PP
Sbjct: 1040 SSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRR----RERSKTPPS 1095
Query: 165 GHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATL-PESRAPDMSPQRISNQLHGTIA 223
E+ LR + S ++ SP +L E+ A D P R+
Sbjct: 1096 NLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRL--------- 1146
Query: 224 VVRPGSQ-ACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282
+ GS+ P + T P + ++P S RP EA +
Sbjct: 1147 -YKSGSEYNLPTFMSLYSPTETPSGSSTTPSS---------------GRPLKSAEEAYEE 1190
Query: 283 SPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPR------LQDLKAREAEAWEEPTEL 336
+ L + + + PH P + P+ PR QD RE +P
Sbjct: 1191 MMRKAELLQRQQGQAAGARGPHGGP----SQPTGPRGLGSFEYQDTTDREYGQAAQPA-A 1245
Query: 337 LGLPSALA------------GMQDLRLEGALHLLLAQQQLRAR-------ARAGSVRPRG 377
G P++L + +R + L A+ + + + A ++ G
Sbjct: 1246 EGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNG 1305
Query: 378 QP-TPGEMLPSL--------PVGSDSEG----PENEGTRAALAAAGLSGGRHTQPAGPGR 424
P TPG L P SDS G P+ T+ H+ PA P
Sbjct: 1306 GPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSS 1365
Query: 425 AQR------TEAAATQDCALDKPLDLSEWGRARGQDTP-KPAGQHGSLSPAA-AHTASPE 476
A + ++ T P G RG TP PAG S SP++ AH+
Sbjct: 1366 ASKEIGMPFSQGPGTPATTAVAPCPA---GLPRGYMTPASPAGSERSPSPSSTAHSYGHS 1422
Query: 477 PPT-----QSGPLTRSPQAL--------------SNGTKGTRVPEQ-----EEASTPMDP 512
P T Q+ L ++P L S+G GT P + +S P+ P
Sbjct: 1423 PTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP 1482
Query: 513 SRPLPGSQLS--LSSPGSTEDEDTGRPLPPPHPQPP-----PHPQPPDLDGHPEPSKAEV 565
S P S P +T + T P P P P P P P G P +
Sbjct: 1483 SSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPST 1542
Query: 566 LRPESDELDETDTPGSEVGLSSQAEATT----STTGEGPECICTQ----EHGQG---PPR 614
R E + + P + L+S A + T ++ P C T+ HG PP
Sbjct: 1543 PRLVWQESSQ-EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601
Query: 615 KRKRASEP 622
+ EP
Sbjct: 1602 VSQLPPEP 1609
Score = 40.4 bits (93), Expect = 0.005
Identities = 82/340 (24%), Positives = 108/340 (31%), Gaps = 78/340 (22%)
Query: 150 PSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDM 209
P G W E PG H A+E G R + G PG + A D+
Sbjct: 3624 PEEGLWPH-DEGGPGRHASAKEHRHGDHGRHSGRHTGEE--------PGRRAAKPHARDL 3674
Query: 210 SPQRISNQLHGTIAVVRPGSQACPADRGPANGTPP-PLPARSSPPSPAYERGLSLDSFLR 268
RP SQ A P G P P A S PS A +
Sbjct: 3675 GRHE-----------ARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK 3723
Query: 269 ASR-----PSAMTHEA-PKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDL 322
SR P+A+ +A P+ P++ P QSP S + AA P+ Q
Sbjct: 3724 GSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQS--QSPSSRQIPSGAASRQPQTQ-- 3779
Query: 323 KAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPG 382
+ + LGL + RL+ +Q R A A S +P G+P PG
Sbjct: 3780 ---------QQQQGLGLQPPQQALTQARLQQQ-----SQPTTRGSAPAAS-QPAGKPQPG 3824
Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPL 442
S + GP QPAGP RA++T + K
Sbjct: 3825 P--------STATGP--------------------QPAGPPRAEQTNGSK----GTAKAP 3852
Query: 443 DLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSG 482
+A+ P PAG P A P G
Sbjct: 3853 QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADG 3892
Score = 38.1 bits (87), Expect = 0.026
Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 24/152 (15%)
Query: 512 PSRPLPGSQLSLSSPGSTEDEDTG-RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPES 570
PS P G QL P + T P+P P P P P P P +P + P
Sbjct: 37 PSAPAGGGQL----PAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKE-----PLG 87
Query: 571 DELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK---RASEPGDKAS 627
++ + TP + E+ T +GP + GP R + R G S
Sbjct: 88 NQRAASPTPKQASATTPGHESPRETRAQGP----AGQEADGPRRTLQVDSRTQRSGRSPS 143
Query: 628 KKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
P RG P SP +P P+S+
Sbjct: 144 VSPDRG-------STPTSPYSVPQIAPLPSST 168
Score = 38.1 bits (87), Expect = 0.026
Identities = 127/514 (24%), Positives = 174/514 (33%), Gaps = 66/514 (12%)
Query: 168 EAEEDHQGVGLRGEEKPAGHRTSP----VAKISPGATLP-ESRAPDMSPQRISNQLHGTI 222
+ E D Q G+ G + SP + ++PG E + PD P I Q H
Sbjct: 2719 QTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD--PLEIGYQAH--- 2773
Query: 223 AVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282
+ P S + R P +P L + SP SP LD+ +S H +P+
Sbjct: 2774 --LPPESLSQLVSRQPPK-SPQVLYSPVSPLSPHR----LLDTSFASSERLNKAHVSPQK 2826
Query: 283 SPKVD---RLCLLNRPL-SLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLG 338
D R L RP+ +L PL+P A S L + + + L
Sbjct: 2827 HFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALP- 2885
Query: 339 LPSALAGMQDLRLEGA----LHLLLAQQ---QLRARA--RAGSVRPRGQP-TPGEMLPSL 388
P++L L HL LA Q QL A + + G P P T +L L
Sbjct: 2886 -PNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLREL 2944
Query: 389 PVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP-----GRAQRTEAAATQDCALDKP-- 441
D E+E T+ A L A G QR E+ A D P
Sbjct: 2945 D--RDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPL 3002
Query: 442 ---------LDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPT-----QSGPLTRS 487
L SE + R Q PAGQ AA A+P PT + P
Sbjct: 3003 RGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQ 3062
Query: 488 PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG--STEDEDTGRPLPPPHPQP 545
A S G P + + P + P P S P ++ RP Q
Sbjct: 3063 YSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT 3122
Query: 546 PPHPQPPDLDGHPEPSKAEVLRPESDELD--ETDTPGSEVGLSS----QAEATTSTTGEG 599
P L P S+A + +P L E P + ++S + A + T+ G
Sbjct: 3123 PMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSG 3182
Query: 600 PECICTQEHGQGP--PRKRKRASEPGDKASKKPS 631
P E G+ P PR R S A PS
Sbjct: 3183 PAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPS 3216
Score = 37.4 bits (85), Expect = 0.045
Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 8/111 (7%)
Query: 527 GSTEDEDTGRPLPPPHP------QPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPG 580
G E+ GR PH + PH QP P+ K + P S E +
Sbjct: 3655 GRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPK--KGQPGYPSSAEYSQPSRAS 3712
Query: 581 SEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPS 631
S +S ++ + GP + ++ Q P+ + R + PG + S+ PS
Sbjct: 3713 SAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPS 3763
Score = 33.9 bits (76), Expect = 0.49
Identities = 46/190 (24%), Positives = 69/190 (36%), Gaps = 21/190 (11%)
Query: 375 PRGQPTPGEMLPSLPVG-SDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQR------ 427
P G G P+ SD EG + +RA A S P+ P +
Sbjct: 1439 PSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFA--SSSPPLSPSSPSESPTFSPGKM 1496
Query: 428 -TEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASP--EPPTQSGPL 484
A A P S+ R+ G TP P G+ +P T + +Q P
Sbjct: 1497 GPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPF 1556
Query: 485 TRSPQALSNGTKGTRVPEQEEASTPM-DPSRPLPGSQ-LSLSSPGSTEDEDTGRPLPPPH 542
A S+ + TR+ +++P+ P+ P + S ++P S LPP
Sbjct: 1557 MVITLA-SDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQ------LPPEP 1609
Query: 543 PQPPPHPQPP 552
P PP P+ P
Sbjct: 1610 PGPPGFPRVP 1619
Score = 30.0 bits (66), Expect = 7.1
Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 37/214 (17%)
Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLS-----PAAAHTA--------SPEPPTQSGPLT- 485
+PL + R+RG P+P + + P A A SP+PP + P T
Sbjct: 256 QPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTA 315
Query: 486 --RSPQALSNGTKGTRVPEQEEAS--TPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPP 541
R P + T VP A+ T + L G SL + ST L
Sbjct: 316 EPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST--------LMSV 367
Query: 542 HPQPPPHPQPPDLDGHP-----EPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTT 596
P+ QP G P + SK +P L PG G ++ A
Sbjct: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKP----LGSGPGPGPAPGAKTEPGARMG-P 422
Query: 597 GEGPECICTQEHGQGPPRKRKRASEPGDKASKKP 630
G GP + + G P+ + + KA+ KP
Sbjct: 423 GSGPGAL-PKTGGTTSPKHGRAEHQAASKAAAKP 455
>gi|50428935 BPY2 interacting protein 1 [Homo sapiens]
Length = 1059
Score = 56.2 bits (134), Expect = 9e-08
Identities = 119/516 (23%), Positives = 173/516 (33%), Gaps = 99/516 (19%)
Query: 180 GEEKPAGHRTSPVAKISPGATLPESRAPD------------MSPQRISNQLHGTIAVVRP 227
G+E+P R P +P T E++ P P+ + + +
Sbjct: 495 GQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKT 554
Query: 228 GSQACPADR-GPA---NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS 283
+QA P R P+ +G PP SPPS AS PSA
Sbjct: 555 NAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGE---------ASPPSAAC------- 598
Query: 284 PKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSAL 343
SP + A L + A E +A E P +P
Sbjct: 599 ---------------------GSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPR 637
Query: 344 AGMQDLR---LEGALHLLLAQQQLRARARAGSVRPRGQPT---PGEMLPSLP--VGSDSE 395
+ EG+ L L+ R G P PT P PSLP VGS
Sbjct: 638 TPSPESHRSPAEGSERLSLSP------LRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHS 691
Query: 396 GPENEGTRAALA-----AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRA 450
+E + +A S + P RA+R+ + D L P + R
Sbjct: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEH--RK 749
Query: 451 RGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPM 510
P PA SP +++ +S ++G L G + T E+ +
Sbjct: 750 AVPMAPAPA------SPGSSNDSSARSQERAGGL---------GAEETPPTSVSESLPTL 794
Query: 511 DPSRPLPGSQLSLSSPGSTEDEDTGR--PLPPPHPQPPPHPQPPDL-DGHPEPSKAEVLR 567
S P+P + + S TE R PLP P PPP P P + PE + R
Sbjct: 795 SDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTAR 854
Query: 568 PESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA- 626
+++ + T P + + A T + + + P R SE G +A
Sbjct: 855 -QTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAP 913
Query: 627 -SKKPSRGRRKLTATEGP-GSPRDAEDHSPSPNSSP 660
S+K S + TAT GP GS S +P SP
Sbjct: 914 LSRKSSTPK---TATRGPSGSASSRPGVSATPPKSP 946
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 55.8 bits (133), Expect = 1e-07
Identities = 104/490 (21%), Positives = 175/490 (35%), Gaps = 68/490 (13%)
Query: 113 EENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEED 172
++ +T + + +R+L P K ++P LL+PS T K G ++
Sbjct: 2265 DDGDTGRIPLSHIRLL----PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDG--- 2317
Query: 173 HQGVGLRGEEKPA------GHRTSPVAKISPGATLPESRAPDMSPQR-ISNQLHGTIAVV 225
G G E+P G + S AK ATL E D P ++ + T
Sbjct: 2318 ----GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSST---- 2369
Query: 226 RPGSQACPADRGPANGTPP---PLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282
PGS+ P + P P P + SP PA+ + + F P+ AP +
Sbjct: 2370 -PGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLI 2428
Query: 283 S-------PKVDRLCLLN------RP---LSLHLQSPHSSPLAPAAAPSDPRLQDLKARE 326
+ PK R + RP L ++ H +P + + L +
Sbjct: 2429 TMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPG 2488
Query: 327 AEAWEEPTELLGL----PSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPG 382
A W+EP LL L P+A + A LAQ+ S P+ P
Sbjct: 2489 AGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPK-SPDKA 2547
Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSG--------GRHTQPAGPGRAQRTEAAATQ 434
+ S+S + G+ ++ +++ SG G G G R +AA+
Sbjct: 2548 QAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASS 2607
Query: 435 DCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNG 494
A S + + + S S +++ ++S + S + S + S+
Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667
Query: 495 TKGTRVPEQEEASTPMDPSRPL----PGSQLSLSSPGSTE-------DEDTGRPLPPPHP 543
+ + E S+ D + P P +Q +L + + + G+ P P P
Sbjct: 2668 SSSSTTDEDSSCSSD-DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726
Query: 544 Q-PPPHPQPP 552
Q PPP P P
Sbjct: 2727 QAPPPQPTQP 2736
Score = 47.0 bits (110), Expect = 6e-05
Identities = 59/241 (24%), Positives = 81/241 (33%), Gaps = 47/241 (19%)
Query: 436 CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGT 495
CA P L + R + T K G+ A S EP ++ R P A + G
Sbjct: 2288 CAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAG----SEEPGAKARGRGRKPSAKAKGD 2343
Query: 496 KGTRV----PEQEEASTPM--DPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP 549
+ + P E STP+ +PS PGS+ SP D+ P P P P P P
Sbjct: 2344 RAATLEEGNPTDEVPSTPLALEPSST-PGSK---KSPPEPVDKRAKAPKARPAP-PQPSP 2398
Query: 550 QPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHG 609
PP P P AE T P + T
Sbjct: 2399 APPAFTSCPAPEPF-------------------------AELPAPATSLAPAPLITMPAT 2433
Query: 610 QGPPRKRKRASEPGDKASKKPSRGRRKLTAT--EGPGSPRDAEDHS-----PSPNSSPWE 662
+ P+K + A E G K ++P L EG SP+ + P + W+
Sbjct: 2434 RPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ 2493
Query: 663 E 663
E
Sbjct: 2494 E 2494
Score = 36.2 bits (82), Expect = 0.100
Identities = 89/356 (25%), Positives = 122/356 (34%), Gaps = 76/356 (21%)
Query: 231 ACPADRGPANGTPPPLPARSSPPSPAYERGLSLD---------SFLRASR-PSAMTHEAP 280
A A R PA+G P PLP Y GL+L SF+ + PSA +H +P
Sbjct: 32 AATAGRLPASGLPGPLPPGK------YMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSP 85
Query: 281 KLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA----------PSD--PRLQDLKAREAE 328
P LS +P + P+ A PS P L E
Sbjct: 86 VPLPS---------DLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPP 136
Query: 329 AWEEPT-ELLGLPSALAGMQDLRLEG-ALHLLLAQQQLRARARAGSVRPRGQPTPGEMLP 386
+ P LG PS + G +L A + A S R TPG
Sbjct: 137 SSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSAR-----TPG---- 187
Query: 387 SLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSE 446
G S G +G+ + A GR +P + A + +DL++
Sbjct: 188 ----GGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQ 243
Query: 447 WGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKG-----TRVP 501
RA G+ P LSP A E T++ L S + NG G V
Sbjct: 244 EARAEGRQDRGPPRLAERLSPFLA-----ESKTKNAALQPSVLTMCNGGAGDVGLPALVA 298
Query: 502 EQ-----EEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552
E +EA+ + +R L ++ L P RP P P P PP P+ P
Sbjct: 299 EAGRGGAKEAARQDEGARLLRRTETLLPGP---------RPCPSPLPPPPAPPKGP 345
Score = 32.7 bits (73), Expect = 1.1
Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 17/130 (13%)
Query: 135 RAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAK 194
R K+G +P L P+PG P E+ + LRG ++P
Sbjct: 1931 RPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAG----- 1985
Query: 195 ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254
PE+ D+ +R S ++ + S A PA A T A+ P S
Sbjct: 1986 -------PEASDDDLWTRRRSERI-----FLHDASAAAPAPVSTAPATKTSRCAKGGPLS 2033
Query: 255 PAYERGLSLD 264
P + G + D
Sbjct: 2034 PRKDAGRAKD 2043
Score = 32.3 bits (72), Expect = 1.4
Identities = 86/344 (25%), Positives = 118/344 (34%), Gaps = 72/344 (20%)
Query: 295 PLSLHLQSP--------HSSPLAPAAAPSDPRLQDLKARE-AEAWEEPTELLGLPSALAG 345
P SLH +P HSS APA S +D A+E A EP L G A
Sbjct: 173 PGSLHSHAPSARTPGGGHSSG-APAKGSSS---RDGPAKERAGRGGEPPPLFGKKDPRAR 228
Query: 346 MQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE---------- 395
++ G ++ Q+ RA R + RG P E L S ++
Sbjct: 229 GEEA--SGPRGVVDLTQEARAEGR----QDRGPPRLAERLSPFLAESKTKNAALQPSVLT 282
Query: 396 ----GPENEGTRAALAAAGLSGGRHT--QPAGPGRAQRTEAAATQDCALDKPLDLSEWGR 449
G + G A +A AG G + Q G +RTE PL
Sbjct: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLP------ 336
Query: 450 ARGQDTPKPAGQHG-----SLSPAAAHTASPE-------------PPTQSGPLTRSPQAL 491
P PA G + +PA +T E P ++ P +
Sbjct: 337 ------PPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQI 390
Query: 492 SNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSP-GSTEDEDTGRPLPPPHPQPPPHPQ 550
++ + R E+E A P P PGS L P G E R L P P P +
Sbjct: 391 ASQARDARARERE-AGRPGVLQAP-PGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVR 448
Query: 551 PPDLDGHPE---PSKAEVLRPESDELDETDTPGSEVGLSSQAEA 591
P P+K E+L+PE+D P G ++Q A
Sbjct: 449 ATRASPDPRAYVPAK-ELLKPEADPRPCERAPRGPAGPAAQQAA 491
Score = 31.2 bits (69), Expect = 3.2
Identities = 73/327 (22%), Positives = 104/327 (31%), Gaps = 74/327 (22%)
Query: 380 TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALD 439
TP + PS GS PE RA A +PA P + A + C
Sbjct: 2360 TPLALEPSSTPGSKKSPPEPVDKRAKAPKA--------RPAPPQPSPAPPAFTS--CPAP 2409
Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499
+P + P PA SL+PA T P T+ P ++ A +G KG R
Sbjct: 2410 EPF----------AELPAPAT---SLAPAPLITM---PATRPKP-KKARAAEESGAKGPR 2452
Query: 500 VP----------EQEEASTPM------------DPSR---PLPGSQLSLSS-PGSTEDED 533
P + E ++P DP P S LSL S P + +
Sbjct: 2453 RPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSE 2512
Query: 534 TGRPLPPPHP-----QPPPHPQPPDLDGHPEPSKAEVLR--PESDELDETDTPGSEVGLS 586
P P +P P D P KA+ + E E + + GS S
Sbjct: 2513 PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSS 2572
Query: 587 SQAEATTSTTGE--------------GPECICTQEHGQGPPRKRKRASEPGDKASKKPSR 632
S + + + T GE G C P +S +S S
Sbjct: 2573 SSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632
Query: 633 GRRKLTATEGPGSPRDAEDHSPSPNSS 659
+++ S + S S +SS
Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSS 2659
Score = 30.8 bits (68), Expect = 4.2
Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 30/142 (21%)
Query: 443 DLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPE 502
++ E G RG + AG TA P G L R P L+ G GT
Sbjct: 945 EMEEKGSKRGLEAAGKAG---------LATAGP------GLLPRKPPGLAAGPAGT---- 985
Query: 503 QEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRP-------LPPPHPQPPPHPQPPDLD 555
+A +P P P +L + + ED +P P HP PP PP
Sbjct: 986 YGKAVSP--PPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTP 1043
Query: 556 G--HPEPSKAEVLRPESDELDE 575
G E + V+ + EL++
Sbjct: 1044 GITRKEEAPENVVEKKDLELEK 1065
Score = 30.0 bits (66), Expect = 7.1
Identities = 47/204 (23%), Positives = 65/204 (31%), Gaps = 31/204 (15%)
Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKV 286
PG + CP+ PPP P + P PA F R + AP P V
Sbjct: 326 PGPRPCPSPL-----PPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVV--APTFVPSV 378
Query: 287 DRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGM 346
+ P+ A+ D R ++ +A + P G P L
Sbjct: 379 EAF------------DERPGPIQIASQARDARAREREAGRPGVLQAPP---GSPRPLDRP 423
Query: 347 QDLRLEGALHLLLAQ----QQLRARARAGSVRPRGQPTPGEML----PSLPVGSDSEGPE 398
+ LR + ++ L + RA S PR E+L P GP
Sbjct: 424 EGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPA 483
Query: 399 NEGTRAALAAAGLSGGRHTQPAGP 422
+ A GL GR P GP
Sbjct: 484 GPAAQQAAKLFGLEPGR-PPPTGP 506
>gi|146219832 myosin light chain kinase 3 [Homo sapiens]
Length = 819
Score = 55.8 bits (133), Expect = 1e-07
Identities = 89/384 (23%), Positives = 130/384 (33%), Gaps = 25/384 (6%)
Query: 275 MTHEAPKLSPKVDRLC--LLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEE 332
+ H ++ K+ +C + + LH +P P A P + D +A W E
Sbjct: 39 LLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAP-GPGGADGVPHI-DTQA----GWPE 92
Query: 333 PTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGS 392
EL+ A RLE ++ A RA A G+ + + M +P
Sbjct: 93 VLELVRAMQQDAAQHGARLEALFRMVAAVD--RAIALVGATFQKSKVADFLMQGRVPWRR 150
Query: 393 DSEGPENEGTRAALAAAG-------LSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLS 445
S G E + + G + G + PG + P+ S
Sbjct: 151 GSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDAREPGEESQKADVLEGTAERLPPIRAS 210
Query: 446 EWGRARGQDTPKPAGQHGSLSPAAA---HTASPEPPTQSGPLTRSPQALSNGTKGTRVPE 502
G Q P G PA A H P P T S + L G + P
Sbjct: 211 GLGADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPS-ENLRTGLELAPAPG 269
Query: 503 QEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK 562
+ +P P G S S P E+ R P P PQ P P P S
Sbjct: 270 RVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLP-AQARATHSG 328
Query: 563 AEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEP 622
E S + E DTPG E+ ++ + + T E P Q QGPP + P
Sbjct: 329 GETPPRISIHIQEMDTPG-EMLMTGRGSLGPTLTTEAPAA--AQPGKQGPPGTGRCLQAP 385
Query: 623 GDKASKKPSRGRRKLTATEGPGSP 646
G + ++ G R+L+ + SP
Sbjct: 386 GTEPGEQTPEGARELSPLQESSSP 409
>gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens]
Length = 2608
Score = 55.5 bits (132), Expect = 2e-07
Identities = 125/541 (23%), Positives = 192/541 (35%), Gaps = 100/541 (18%)
Query: 130 DRPKPRAKEGTSDPPSPLLLP----SPGGWKAITEKPPGGHEEAEEDHQG-VGLRGEEKP 184
+R + ++G S S +L SPG + E+P +E EED G + E+
Sbjct: 1184 ERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEED 1243
Query: 185 AGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPP 244
G GA P++ P + + + TI + S + P + PA PP
Sbjct: 1244 CG-----------GA--PDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPP 1290
Query: 245 ---PLPARSSPPSPAYERGLS-LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300
PLP S A L+ L + S + E L+ + L L SL
Sbjct: 1291 STVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350
Query: 301 QSPHSSPLAPAAAPS---------DPRLQDLKARE-------------AEAWEEPTELLG 338
+ S APA P+ PR+Q L+ ++ A T+ +G
Sbjct: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVG 1410
Query: 339 LPSALAGMQDLRLEGALHLLLAQ--------QQLRARARAGSVRPRGQPTPGEMLPSLPV 390
+ LA +Q E L Q + R+ AR G RPR + + P
Sbjct: 1411 MRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPT 1470
Query: 391 G----SDSEGPENEGTRAALAAAGLSGGRHTQPAGP-GRAQRTEAAATQDCALDKPLDLS 445
G SD + + T L A L GG +PA + +R+ A Q +++K
Sbjct: 1471 GPLPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKA---- 1526
Query: 446 EWGRARGQDTPKPAGQHGSLSPAAAH-TASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504
K + G L+P+ AH A +P +S L P LS+ Q+
Sbjct: 1527 ---------QCKKSSCQGGLAPSVAHRVAQLKPKVKSKGL---PTGLSS--------FQQ 1566
Query: 505 EASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPH--PQPPDLDGHPEPSK 562
+ +TP R S G+T HPQP H + P P +
Sbjct: 1567 KEATPGGRIREKLSRAKSAKVSGATR-----------HPQPKGHGSRETPRCPAQPSVAA 1615
Query: 563 AEVLRPESDELD-----ETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK 617
++ D D T+ P E GL A+ + G P + E Q +K++
Sbjct: 1616 SQEAGNGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKE 1675
Query: 618 R 618
R
Sbjct: 1676 R 1676
Score = 45.4 bits (106), Expect = 2e-04
Identities = 129/557 (23%), Positives = 183/557 (32%), Gaps = 91/557 (16%)
Query: 161 KPPGGHEEAEEDHQGVGLRGEEKP------AGHRTSPVA---KISPGATLPESRAPDMSP 211
KP H + EE Q + KP A SP A K+ P P+ + P SP
Sbjct: 947 KPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSP 1006
Query: 212 Q---RISNQLHGTIAVVR---PGSQACPADRGPANGTPPPLPARSSPPS--PAYER---- 259
R S + PGS+ A+ G +S P P Y R
Sbjct: 1007 TPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAG 1066
Query: 260 -GLSLDSFLRASR---PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPS 315
G SL S + +S P M AP P+ R L P +S L A +
Sbjct: 1067 LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREA 1126
Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRP 375
QDL A P PS L G+Q+L+ L + +A + G R
Sbjct: 1127 T---QDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGARE 1183
Query: 376 RGQPTPGEMLPSLPVGSDSEGPENE-GTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQ 434
GE PS G+ S+ E G+ AL G QPA P + E Q
Sbjct: 1184 ERSREEGEQGPS--SGASSQVLEQRAGSPGALEDEG------EQPA-PEEDELEEDELGQ 1234
Query: 435 DCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTA--------SPEPPTQSGPLTR 486
D D G P+ +L A + P+PP SGP +
Sbjct: 1235 QSMEDSEEDCG--GAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPST 1292
Query: 487 SPQALSNGTKG------------------TRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528
P S+G G VPE+EE + + L + S +
Sbjct: 1293 VPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFN-LQHLATLATAWSLVEA 1351
Query: 529 TEDEDTGRPLPPPHPQPPPHPQ-PPDLD----GHPEPSKAEVLRPESDELDETDTPGSEV 583
+ + P PP P P+ P + K + + P +D DT EV
Sbjct: 1352 AGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDT--QEV 1409
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643
G+ + +E + R +++ D++S+ P+R GP
Sbjct: 1410 GMRVRLAELQRR---------YKEKQRELARLQRKHDHERDESSRSPAR--------RGP 1452
Query: 644 GSPRDAEDHSPSPNSSP 660
G PR + S P P
Sbjct: 1453 GRPRKRKHSSSLPAPRP 1469
Score = 44.7 bits (104), Expect = 3e-04
Identities = 77/298 (25%), Positives = 104/298 (34%), Gaps = 65/298 (21%)
Query: 426 QRTEAAATQDCALDKPLDLSEWGRARG-QDTPKPAG----QHGSLSPAAAHTASPE---- 476
Q+ AA Q D+ LDL E + + + T KP G+ SPAA T P
Sbjct: 937 QQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHP 996
Query: 477 ------------PPTQSGPLTRSPQALSNGTKGTRVPEQEEAS----------------T 508
PP S P T + S+ G+RV EE +
Sbjct: 997 PDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDL 1056
Query: 509 PMDPSRPLPGSQLSLSS---PGSTEDEDTGRPLPP-PHPQP-----PPHPQPPDLDGHPE 559
P RP+ G SL S + ED +T + P P+P P P P E
Sbjct: 1057 PPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEE 1116
Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTG------------EGPECICTQE 607
P R + +L T P +E G +A + G GPE
Sbjct: 1117 PGLLSGAREATQDLAATPYP-TERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAH 1175
Query: 608 HGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAED--HSPSPNSSPWEE 663
QG R+ +R+ E G++ PS G + GSP ED P+P EE
Sbjct: 1176 STQGGARE-ERSREEGEQG---PSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEE 1229
Score = 32.0 bits (71), Expect = 1.9
Identities = 33/114 (28%), Positives = 42/114 (36%), Gaps = 7/114 (6%)
Query: 167 EEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVR 226
E H+ PAG P A PG P S P M+ S++L G+
Sbjct: 15 ERGSLGHRSAAAAARLAPAGPAAQPPAHFQPGKYFP-SPLP-MASHTASSRLMGSSPASS 72
Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAP 280
+ G A T P P+ SSPP AY S + S +HEAP
Sbjct: 73 FMGSFLTSSLGSAASTHPSGPS-SSPPEQAYRGSHPTTSQIWFSH----SHEAP 121
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo
sapiens]
Length = 2524
Score = 55.1 bits (131), Expect = 2e-07
Identities = 49/205 (23%), Positives = 78/205 (38%), Gaps = 18/205 (8%)
Query: 450 ARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP 509
A G + P+ G S A T + T+S P + A G G + P A P
Sbjct: 726 ASGNEVPR-----GECSGPA--TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP 778
Query: 510 MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPE 569
P + + + E TG P PP P PP PP + E + P
Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPP--PAPPSPSAPPPVVPKEEKEEETAAAPP 836
Query: 570 SDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPR----KRKRASEPGDK 625
+E +E P +E + T E + CT+E +GP + + A+ G
Sbjct: 837 VEEGEEQKPPAAE-----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGAL 891
Query: 626 ASKKPSRGRRKLTATEGPGSPRDAE 650
++K G + T + G+P+D++
Sbjct: 892 KAEKKEGGSGRATTAKSSGAPQDSD 916
Score = 43.1 bits (100), Expect = 8e-04
Identities = 107/471 (22%), Positives = 149/471 (31%), Gaps = 101/471 (21%)
Query: 107 EMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGH 166
E +G+ E + EE + L G+ PR G P+ + S TE P H
Sbjct: 706 EASGVSGNEEEMVEEAEALHASGNEV-PR---GECSGPATVNNSSD------TESIPSPH 755
Query: 167 EEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVR 226
EA +D G G + PA + GA P P P+ I T
Sbjct: 756 TEAAKD---TGQNGPKPPA----------TLGADGPPPGPPTPPPEDIPAPTEPT----- 797
Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKV 286
PA TPPP P S P P + + A+ P E K P
Sbjct: 798 ------PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEE--TAAAPPVEEGEEQK-PPAA 848
Query: 287 DRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGM 346
+ L + + P S A + +D +A EA A
Sbjct: 849 EELAVDTG----KAEEPVKSECTEEAEEGPAKGKDAEAAEATA----------------- 887
Query: 347 QDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAAL 406
EGAL A+++ RA + + G P + + E + R
Sbjct: 888 -----EGALK---AEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLS 939
Query: 407 AAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLS 466
L P G RA + + KPLDL + + P H
Sbjct: 940 PRPSL-----LTPTGDPRA---------NASPQKPLDLKQLKQRAAAIPPIVTKVHEPPR 985
Query: 467 PAAAHT----ASPEPPTQSGPLTRSPQALSNGTKG----TRVPEQEEASTPM-DPSRPLP 517
AA T +P PP P + +PQ + +G P +EA P+ P+
Sbjct: 986 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAE 1045
Query: 518 GSQLSLSSPGSTEDEDTGRPLP-PPHPQPPPHPQPPDLD-------GHPEP 560
+L PG +G P P PP P PD GHP P
Sbjct: 1046 AQKL----PGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1092
Score = 33.9 bits (76), Expect = 0.49
Identities = 135/656 (20%), Positives = 214/656 (32%), Gaps = 188/656 (28%)
Query: 28 ELNSERCRDAQRIEELFS-----KNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQEL 82
E NSE Q+ EL S + E+ +T K+ L LE+ R + ++ +
Sbjct: 589 EANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGL--LEHGRNWSAIARMVGSKTV 646
Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSD 142
++ + F QNL I + + LK E E K+ + A E +
Sbjct: 647 SQCKNFYFNYKKRQNLDEIL----QQHKLKMEKERNARRKKK------KAPAAASEEAAF 696
Query: 143 PPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLP 202
PP + G EE E+ + + G E P G + P AT+
Sbjct: 697 PPVV------EDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGP-------ATV- 742
Query: 203 ESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPP--LPARSSPPSPAYERG 260
N T ++ P ++A D G NG PP L A PP P
Sbjct: 743 -------------NNSSDTESIPSPHTEAAK-DTGQ-NGPKPPATLGADGPPPGP----- 782
Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320
P+ + P + P S +P + P AP + + P +
Sbjct: 783 -----------PTPPPEDIPAPTEPT--------PASEATGAP-TPPPAPPSPSAPPPVV 822
Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380
+ +E E P G ++L ++ + + A G +
Sbjct: 823 PKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAK------ 876
Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG-GRHTQPAGPGRAQRTEAAATQDCALD 439
G D+E E A A G GR T G Q ++++AT C+ D
Sbjct: 877 ----------GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSAT--CSAD 924
Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499
+ +D +E G +P+P+ + P A ASP+ P L + A+
Sbjct: 925 E-VDEAEGGDKNRLLSPRPSLLTPTGDPRA--NASPQKPLDLKQLKQRAAAIPPIVTKVH 981
Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE 559
P +E+A+ P++P P P P PP + QP
Sbjct: 982 EPPREDAA----PTKPAP-----------------------PAPPPPQNLQP-------- 1006
Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA 619
E+D P Q+ G P K +
Sbjct: 1007 ---------------ESDAP--------------------------QQPGSSPRGKSRSP 1025
Query: 620 SEPGDKASKKP------SRGRRKLTA-----TEG---PGSPRD---AEDHSPSPNS 658
+ P DK ++KP + +KL T G P PR+ A H+P P++
Sbjct: 1026 APPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSA 1081
>gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens]
Length = 1312
Score = 54.7 bits (130), Expect = 3e-07
Identities = 100/434 (23%), Positives = 156/434 (35%), Gaps = 77/434 (17%)
Query: 233 PADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLL 292
P+ P+ PPP PA +PP+P ++ P T EA P ++
Sbjct: 201 PSSSSPSPPPPPPPPAPPAPPAPRFD----------IYDPFHPTDEAYSPPPAPEQKYDP 250
Query: 293 NRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLE 352
P S+P + A PS ++ + E E E+ E GL +++ + + L
Sbjct: 251 FEPTG-------SNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISE-TLA 302
Query: 353 GALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRA--ALAAAG 410
G Q S RP QPT P P P+ + TRA A+
Sbjct: 303 GIYDDNSLSQDFPGDE---SPRPDAQPTQPTPAPGTP-------PQVDSTRADGAMRRRV 352
Query: 411 LSGGRHTQPAGPGRAQRTEAAATQDCALDKPL------DLSEWGRARGQDTP-------K 457
G + G+ E AL PL ++ E + ++ P +
Sbjct: 353 FVVGTEAEACREGKVS-VEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFR 411
Query: 458 PAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQ--------ALSNGTKGTRVPEQEEASTP 509
P G+ +PAA+ T + +P Q P R+P+ A S+G +V E A P
Sbjct: 412 PGGRAARPTPAASATPTAQPLPQP-PAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAP 470
Query: 510 MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPE 569
P+ L L T+ + R P P P P P G P K+ R
Sbjct: 471 --PAADSRWGGLDLRRKILTQRRERYR---QRSPSPAPAPAPAAAAGPPTRKKSRRERKR 525
Query: 570 SDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKAS-- 627
S E + +A +++S T P + + + R R +PG AS
Sbjct: 526 SGE-------------AKEAASSSSGTQPAPPAPASPWDSK---KHRSRDRKPGSHASSS 569
Query: 628 -KKPSRGRRKLTAT 640
++ SR R + +T
Sbjct: 570 ARRRSRSRSRSRST 583
Score = 36.2 bits (82), Expect = 0.100
Identities = 44/184 (23%), Positives = 67/184 (36%), Gaps = 16/184 (8%)
Query: 485 TRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ 544
T SPQ SN ++ T + P+ P P + SSP + + P PPP P
Sbjct: 159 TVSPQ--SNSSRPTCARHLTLGTGDGGPAPP-PAPSSASSSPSPSPSSSSPSPPPPPPPP 215
Query: 545 PPPHPQPPDLDGHP--EPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPEC 602
PP P P D + P+ P + E + P G + + A T + E
Sbjct: 216 APPAPPAPRFDIYDPFHPTDEAYSPPPAPE--QKYDPFEPTGSNPSSSAGTPSPEE---- 269
Query: 603 ICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRD--AEDHSPSPNSSP 660
+E + + + E + S+ SR L S D SP P++ P
Sbjct: 270 ---EEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQP 326
Query: 661 WEET 664
+ T
Sbjct: 327 TQPT 330
Score = 34.7 bits (78), Expect = 0.29
Identities = 37/152 (24%), Positives = 49/152 (32%), Gaps = 33/152 (21%)
Query: 448 GRARGQDTPKPAGQHGSLSPA-AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEA 506
G G P PA S SP+ + ++SP PP P
Sbjct: 178 GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPP----------------------- 214
Query: 507 STPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP---QPPDLDGHPEPSKA 563
P P+ P P + + P DE P P P P P G P P +
Sbjct: 215 --PAPPAPPAP--RFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEE 270
Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTST 595
E E +E +E + E GLS + T
Sbjct: 271 E--EEEEEEEEEEEDEEEEEGLSQSISRISET 300
Score = 31.2 bits (69), Expect = 3.2
Identities = 99/457 (21%), Positives = 153/457 (33%), Gaps = 71/457 (15%)
Query: 247 PARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDR-LCLLNRPLSLHLQSPHS 305
PA + PPS + G DS R + P P + D L + R +++ + S
Sbjct: 663 PAPAPPPSGSTSCG-DRDSRRRGAVP-------PSIQDLTDHDLFAIKRTITVG-RLDKS 713
Query: 306 SPLAPAAAP-SDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQL 364
P P+ AP S P+ + L E + EE + +D R GA + ++
Sbjct: 714 DPRGPSPAPASSPKREVLYDSEGLSGEER-------GGKSSQKDRRRSGAASSSSSSREK 766
Query: 365 RARARA--GSVRPRGQPT-------------PGEMLPSLPVGSDSEGPENEGTRAALAAA 409
+R +A G R R + P E PS G + P + G+ ++ +++
Sbjct: 767 GSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSS--GPPPKPPVSSGSGSSSSSS 824
Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGR--ARGQDTPKPAGQHGSLSP 467
S + + R ++T L G +R +++ P + +P
Sbjct: 825 SCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAP 884
Query: 468 AAAHTASP--EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLS- 524
A+P P ++ ++ + GTKG P + G Q+SL
Sbjct: 885 TEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKK 944
Query: 525 -----------SPGSTEDEDTGRP-------LPPPHPQPPPHPQPPDLDGHPEPSKAEVL 566
+ G+ E +G PPP PPP PD K
Sbjct: 945 SKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKT--- 1001
Query: 567 RPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA 626
PE L E T E G+ AE E E +E + P S
Sbjct: 1002 -PEVSFLPEEAT--EEAGVRGGAEEEEEEEEEEEE---EEEEEEQQPATTTATSTAAAAP 1055
Query: 627 SKKPSRGRR--KLTATEGPGSPRDAEDHSPSPNSSPW 661
S PS G A +GP S P P PW
Sbjct: 1056 STAPSAGSTAGDSGAEDGPASRVSQLPTLPPP--MPW 1090
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 53.9 bits (128), Expect = 5e-07
Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
E+ + T + K S P S+ + G A+ P + PA+
Sbjct: 168 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 226
Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
TP P P A ++P PA S + + P+ AP +PK
Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 285
Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353
P +S ++P PA P P K +EPT P+ E
Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 340
Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409
A + A + PT P E P+ P + + P T++A
Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400
Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468
T+ A P + T++ A P + + + TPK PA
Sbjct: 401 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528
T P P T P +P+ + T P E P P +P P + L+ +
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 517
Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587
T +E T P P P P P P+ P P+ + P + + TP
Sbjct: 518 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 567
Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640
+ T TT +G +E P+K EP KP+ K TA
Sbjct: 568 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625
Query: 641 EGPGSPRDAEDHSPSPNS 658
P P P+P +
Sbjct: 626 TTPKEPAPTTPKEPAPTT 643
Score = 52.0 bits (123), Expect = 2e-06
Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%)
Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
E + K+ +VL +P P+A+ T P L +P T K P E
Sbjct: 180 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 234
Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229
+ E P +++P P T + AP + +
Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294
Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289
P + P T P PA ++P PA + P+ T E +PK
Sbjct: 295 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348
+P ++P PA P +P K +EP P+
Sbjct: 351 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 398
Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408
E A + + + TP E P+ P P+
Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458
Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465
A + + T P P E A T K L + + KPA L
Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 514
Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523
+P +P P + P T P+A + T P + P P P P + + +
Sbjct: 515 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572
Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583
++P T P P +P P P P + + P + + TP
Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636
+ + A T+ G P + +E P+K P S KP+ K
Sbjct: 633 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690
Query: 637 LTATEGPGSPRDAEDHSPSPNS 658
TA P P P+P +
Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTT 712
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%)
Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444
PSLP SD S+ + + + Q + G+ + T A TQ DL
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187
Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504
+ + + TPK + + PA P P T P + +P+ + T
Sbjct: 188 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 237
Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561
S P P P P + S ++P T P P P P P +P P+
Sbjct: 238 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 296
Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
+ P + + TP E ++ E T +T P E
Sbjct: 297 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 339
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
P K+P+ K A P P P+P ++
Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377
Score = 40.4 bits (93), Expect = 0.005
Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%)
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249
SP P T P+ AP +P++ + A P A + PA TP PA
Sbjct: 419 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 476
Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305
++P A + P +T P KL+P P L +P
Sbjct: 477 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524
Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358
+P P AAAP+ P+ + A P E P+ +G
Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 582
Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418
L + P+ +P P E+ P+ S + A + +
Sbjct: 583 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 632
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476
P P T T L +P + A + P G + S A T E
Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692
Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535
P T P +P+ + T T P E STP P + SP + E +
Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 748
Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592
P P P P P P +K E+ D+ E D TP + + T
Sbjct: 749 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 807
Query: 593 TSTTGEGPE 601
+TT + E
Sbjct: 808 ATTTEKTTE 816
Score = 33.1 bits (74), Expect = 0.84
Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%)
Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508
T KP SL P + + T + E ++ T + + S K +E S
Sbjct: 120 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 179
Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567
++ L + L+ P + T P L P P P+ P EP+ +
Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239
Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619
+ + T + + A T+T T + P T+E P K A
Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 296
Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658
EP KKP+ K A P P P+P +
Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 53.9 bits (128), Expect = 5e-07
Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
E+ + T + K S P S+ + G A+ P + PA+
Sbjct: 209 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 267
Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
TP P P A ++P PA S + + P+ AP +PK
Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 326
Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353
P +S ++P PA P P K +EPT P+ E
Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 381
Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409
A + A + PT P E P+ P + + P T++A
Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441
Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468
T+ A P + T++ A P + + + TPK PA
Sbjct: 442 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528
T P P T P +P+ + T P E P P +P P + L+ +
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 558
Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587
T +E T P P P P P P+ P P+ + P + + TP
Sbjct: 559 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 608
Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640
+ T TT +G +E P+K EP KP+ K TA
Sbjct: 609 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666
Query: 641 EGPGSPRDAEDHSPSPNS 658
P P P+P +
Sbjct: 667 TTPKEPAPTTPKEPAPTT 684
Score = 52.0 bits (123), Expect = 2e-06
Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%)
Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
E + K+ +VL +P P+A+ T P L +P T K P E
Sbjct: 221 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 275
Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229
+ E P +++P P T + AP + +
Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335
Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289
P + P T P PA ++P PA + P+ T E +PK
Sbjct: 336 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348
+P ++P PA P +P K +EP P+
Sbjct: 392 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 439
Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408
E A + + + TP E P+ P P+
Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499
Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465
A + + T P P E A T K L + + KPA L
Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 555
Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523
+P +P P + P T P+A + T P + P P P P + + +
Sbjct: 556 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613
Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583
++P T P P +P P P P + + P + + TP
Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636
+ + A T+ G P + +E P+K P S KP+ K
Sbjct: 674 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731
Query: 637 LTATEGPGSPRDAEDHSPSPNS 658
TA P P P+P +
Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTT 753
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%)
Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444
PSLP SD S+ + + + Q + G+ + T A TQ DL
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228
Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504
+ + + TPK + + PA P P T P + +P+ + T
Sbjct: 229 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 278
Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561
S P P P P + S ++P T P P P P P +P P+
Sbjct: 279 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 337
Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
+ P + + TP E ++ E T +T P E
Sbjct: 338 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 380
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
P K+P+ K A P P P+P ++
Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418
Score = 40.4 bits (93), Expect = 0.005
Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%)
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249
SP P T P+ AP +P++ + A P A + PA TP PA
Sbjct: 460 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 517
Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305
++P A + P +T P KL+P P L +P
Sbjct: 518 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565
Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358
+P P AAAP+ P+ + A P E P+ +G
Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 623
Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418
L + P+ +P P E+ P+ S + A + +
Sbjct: 624 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 673
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476
P P T T L +P + A + P G + S A T E
Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733
Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535
P T P +P+ + T T P E STP P + SP + E +
Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 789
Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592
P P P P P P +K E+ D+ E D TP + + T
Sbjct: 790 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 848
Query: 593 TSTTGEGPE 601
+TT + E
Sbjct: 849 ATTTEKTTE 857
Score = 33.1 bits (74), Expect = 0.84
Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%)
Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508
T KP SL P + + T + E ++ T + + S K +E S
Sbjct: 161 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 220
Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567
++ L + L+ P + T P L P P P+ P EP+ +
Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280
Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619
+ + T + + A T+T T + P T+E P K A
Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 337
Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658
EP KKP+ K A P P P+P +
Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 53.9 bits (128), Expect = 5e-07
Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
E+ + T + K S P S+ + G A+ P + PA+
Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 319
Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
TP P P A ++P PA S + + P+ AP +PK
Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 378
Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353
P +S ++P PA P P K +EPT P+ E
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 433
Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409
A + A + PT P E P+ P + + P T++A
Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493
Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468
T+ A P + T++ A P + + + TPK PA
Sbjct: 494 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528
T P P T P +P+ + T P E P P +P P + L+ +
Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 610
Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587
T +E T P P P P P P+ P P+ + P + + TP
Sbjct: 611 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 660
Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640
+ T TT +G +E P+K EP KP+ K TA
Sbjct: 661 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718
Query: 641 EGPGSPRDAEDHSPSPNS 658
P P P+P +
Sbjct: 719 TTPKEPAPTTPKEPAPTT 736
Score = 52.0 bits (123), Expect = 2e-06
Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%)
Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
E + K+ +VL +P P+A+ T P L +P T K P E
Sbjct: 273 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 327
Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229
+ E P +++P P T + AP + +
Sbjct: 328 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387
Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289
P + P T P PA ++P PA + P+ T E +PK
Sbjct: 388 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 443
Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348
+P ++P PA P +P K +EP P+
Sbjct: 444 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 491
Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408
E A + + + TP E P+ P P+
Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551
Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465
A + + T P P E A T K L + + KPA L
Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 607
Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523
+P +P P + P T P+A + T P + P P P P + + +
Sbjct: 608 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665
Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583
++P T P P +P P P P + + P + + TP
Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636
+ + A T+ G P + +E P+K P S KP+ K
Sbjct: 726 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783
Query: 637 LTATEGPGSPRDAEDHSPSPNS 658
TA P P P+P +
Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTT 805
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%)
Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444
PSLP SD S+ + + + Q + G+ + T A TQ DL
Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280
Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504
+ + + TPK + + PA P P T P + +P+ + T
Sbjct: 281 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 330
Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561
S P P P P + S ++P T P P P P P +P P+
Sbjct: 331 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389
Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
+ P + + TP E ++ E T +T P E
Sbjct: 390 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 432
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
P K+P+ K A P P P+P ++
Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470
Score = 40.4 bits (93), Expect = 0.005
Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%)
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249
SP P T P+ AP +P++ + A P A + PA TP PA
Sbjct: 512 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 569
Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305
++P A + P +T P KL+P P L +P
Sbjct: 570 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617
Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358
+P P AAAP+ P+ + A P E P+ +G
Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 675
Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418
L + P+ +P P E+ P+ S + A + +
Sbjct: 676 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 725
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476
P P T T L +P + A + P G + S A T E
Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785
Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535
P T P +P+ + T T P E STP P + SP + E +
Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 841
Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592
P P P P P P +K E+ D+ E D TP + + T
Sbjct: 842 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 900
Query: 593 TSTTGEGPE 601
+TT + E
Sbjct: 901 ATTTEKTTE 909
Score = 33.1 bits (74), Expect = 0.84
Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%)
Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508
T KP SL P + + T + E ++ T + + S K +E S
Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272
Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567
++ L + L+ P + T P L P P P+ P EP+ +
Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332
Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619
+ + T + + A T+T T + P T+E P K A
Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 389
Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658
EP KKP+ K A P P P+P +
Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 53.9 bits (128), Expect = 5e-07
Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%)
Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
E+ + T + K S P S+ + G A+ P + PA+
Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 360
Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
TP P P A ++P PA S + + P+ AP +PK
Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 419
Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353
P +S ++P PA P P K +EPT P+ E
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 474
Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409
A + A + PT P E P+ P + + P T++A
Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534
Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468
T+ A P + T++ A P + + + TPK PA
Sbjct: 535 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593
Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528
T P P T P +P+ + T P E P P +P P + L+ +
Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 651
Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587
T +E T P P P P P P+ P P+ + P + + TP
Sbjct: 652 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 701
Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640
+ T TT +G +E P+K EP KP+ K TA
Sbjct: 702 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759
Query: 641 EGPGSPRDAEDHSPSPNS 658
P P P+P +
Sbjct: 760 TTPKEPAPTTPKEPAPTT 777
Score = 52.0 bits (123), Expect = 2e-06
Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%)
Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173
E + K+ +VL +P P+A+ T P L +P T K P E
Sbjct: 314 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 368
Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229
+ E P +++P P T + AP + +
Sbjct: 369 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428
Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289
P + P T P PA ++P PA + P+ T E +PK
Sbjct: 429 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 484
Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348
+P ++P PA P +P K +EP P+
Sbjct: 485 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 532
Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408
E A + + + TP E P+ P P+
Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592
Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465
A + + T P P E A T K L + + KPA L
Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 648
Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523
+P +P P + P T P+A + T P + P P P P + + +
Sbjct: 649 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706
Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583
++P T P P +P P P P + + P + + TP
Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636
+ + A T+ G P + +E P+K P S KP+ K
Sbjct: 767 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824
Query: 637 LTATEGPGSPRDAEDHSPSPNS 658
TA P P P+P +
Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTT 846
Score = 45.8 bits (107), Expect = 1e-04
Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%)
Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444
PSLP SD S+ + + + Q + G+ + T A TQ DL
Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321
Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504
+ + + TPK + + PA P P T P + +P+ + T
Sbjct: 322 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 371
Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561
S P P P P + S ++P T P P P P P +P P+
Sbjct: 372 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 430
Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
+ P + + TP E ++ E T +T P E
Sbjct: 431 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 473
Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659
P K+P+ K A P P P+P ++
Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511
Score = 40.4 bits (93), Expect = 0.005
Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%)
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249
SP P T P+ AP +P++ + A P A + PA TP PA
Sbjct: 553 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 610
Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305
++P A + P +T P KL+P P L +P
Sbjct: 611 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658
Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358
+P P AAAP+ P+ + A P E P+ +G
Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 716
Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418
L + P+ +P P E+ P+ S + A + +
Sbjct: 717 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 766
Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476
P P T T L +P + A + P G + S A T E
Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826
Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535
P T P +P+ + T T P E STP P + SP + E +
Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 882
Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592
P P P P P P +K E+ D+ E D TP + + T
Sbjct: 883 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 941
Query: 593 TSTTGEGPE 601
+TT + E
Sbjct: 942 ATTTEKTTE 950
Score = 33.1 bits (74), Expect = 0.84
Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%)
Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508
T KP SL P + + T + E ++ T + + S K +E S
Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313
Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567
++ L + L+ P + T P L P P P+ P EP+ +
Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373
Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619
+ + T + + A T+T T + P T+E P K A
Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 430
Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658
EP KKP+ K A P P P+P +
Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 53.9 bits (128), Expect = 5e-07
Identities = 123/534 (23%), Positives = 164/534 (30%), Gaps = 74/534 (13%)
Query: 163 PGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTI 222
PG E D V +G+ K GH TS K PG E++
Sbjct: 377 PGDTPTDEPDALYVACQGQPK-GGHVTSMQPK-EPGPLQCEAKP---------------- 418
Query: 223 AVVRPGSQACPADRGPANGTPPPLPA-RSSPPSPAYERGLSLDSFLRASRPSAMTHEAPK 281
+ + G Q P P N P LP SP SP E P++ EA +
Sbjct: 419 -LGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEES-----------PTSPPPEASR 466
Query: 282 LSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSD----PRLQDLKAREAEAWEEPTEL 336
LSP + L P +LHL P SPL+P S P E P E
Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526
Query: 337 LGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEG 396
P+ + L + L P P + P S
Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP--PPEASRLSPPPEESPMSPP 584
Query: 397 PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTP 456
PE A+ L P P + + + L P + S +
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPM 644
Query: 457 KPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPL 516
P + LSP + PP +S PL+ P+ PE S P + S
Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEES-PLSPPPEESPTSPP----PEASRLSPPPEDSPTS 699
Query: 517 PGSQLSLSSPGSTEDEDTGRPLP---------PPHPQPPPHPQPPDLDGHPE-----PSK 562
P + SP S ED+ LP P PQ P + P L PE P
Sbjct: 700 PPPE---DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756
Query: 563 AEV-LRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621
E L P+++E + P + E S EGP E P+ +
Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816
Query: 622 PGDK---ASKKPSRGRRKLTATEGPGSPRDAEDH----------SPSPNSSPWE 662
P + S +P + E SPR E H SP P P E
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870
Score = 46.6 bits (109), Expect = 7e-05
Identities = 104/436 (23%), Positives = 145/436 (33%), Gaps = 75/436 (17%)
Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANG-- 241
P R SP + SP + PE P+ ++ + P + P P
Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680
Query: 242 TPPPLPARSSPP------SPAYERGL-------SLDSFLRASRPSAMTHEAPKLSPKVDR 288
+PPP +R SPP SP E SL S P E P+L P+ +
Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740
Query: 289 LCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348
L RP + PH SP P +P L +A E +P E P A ++
Sbjct: 741 PHLSPRP-----EEPHLSP-----RPEEPHLSP-QAEEPHLSPQPEE----PCLCAVPEE 785
Query: 349 LRL----EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRA 404
L EG HL ++L + + P P P E S P++E
Sbjct: 786 PHLSPQAEGP-HLSPQPEELHLSPQ--TEEPHLSPVPEEPCLSPQPEESHLSPQSE--EP 840
Query: 405 ALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS 464
L+ + P + R E + P +L + P S
Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF----------PPPGEPS 890
Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLS 524
LSP A EP PL+ P+ L G P P DP P ++ +
Sbjct: 891 LSPLLGEPALSEPGEP--PLSPLPEELPLSPSGE--PSLSPQLMPPDPLPPPLSPIITAA 946
Query: 525 SP-------------GSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESD 571
+P G+ D D PL P + P P P PEP +L P
Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP--- 1003
Query: 572 ELDETDTPGSEVGLSS 587
+PGS VG +S
Sbjct: 1004 ------SPGSPVGPAS 1013
Score = 45.4 bits (106), Expect = 2e-04
Identities = 133/572 (23%), Positives = 207/572 (36%), Gaps = 110/572 (19%)
Query: 22 LQNKLLELNSERCRDAQRIEEL--FSKNHQLREQQKTLKENLRVLENRLRAGLCDRCMVT 79
LQ L+ + + AQ + L + QL++QQ+ ++ + L+ + + +
Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ-------LQQ 3928
Query: 80 QELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEG 139
Q+L +++QQ Q LQ+ + L+++ + L+++ ++ + + + + + G
Sbjct: 3929 QQLQQQQQQ-------QQLQQ-----QQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976
Query: 140 TSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGA 199
+ LL P ++ ++ +G KP H +SP A + P
Sbjct: 3977 LLNQSRTLLSP----------------QQQQQQQVALGPGMPAKPLQHFSSPGA-LGPTL 4019
Query: 200 TLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYER 259
L + P S A GP+ PL ++P S A E
Sbjct: 4020 LLTGKEQNTVDPAVSSE-----------------ATEGPSTHQGGPLAIGTTPESMATEP 4062
Query: 260 GLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS-SPLAPAAAPSDPR 318
G S S S + P+ P+ L L PL L Q S L A S +
Sbjct: 4063 GEVKPSL---SGDSQLLLVQPQPQPQPSSL-QLQPPLRLPGQQQQQVSLLHTAGGGSHGQ 4118
Query: 319 LQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQ 378
L + EA + LL PS G Q + +LL QQ + R + P+
Sbjct: 4119 LGSGSSSEASS---VPHLLAQPSVSLGDQPGSM--TQNLLGPQQPMLERPMQNNTGPQ-P 4172
Query: 379 PTPGEMLPSLPVGSDSEG----PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQ 434
P PG +L S G G P RA L L+ + P + Q+ +A Q
Sbjct: 4173 PKPGPVLQS---GQGLPGVGIMPTVGQLRAQLQGV-LAKNPQLRHLSPQQQQQLQALLMQ 4228
Query: 435 -----DCALDKPLDLSEWGRARGQDTPK-------------PAGQHGSLSPAAAHTASPE 476
A+ + E G Q +P P Q G L A
Sbjct: 4229 RQLQQSQAVRQTPPYQEPGT---QTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG 4285
Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536
PP P P ALS G V S+P +P RP SQL P + T
Sbjct: 4286 PPRLPAP----PGALSTGPVLGPVHPTPPPSSPQEPKRP---SQL----PSPSSQLPTEA 4334
Query: 537 PLPPPHPQPPPHPQPPDLD---GHPEPSKAEV 565
LPP HP P PQ P L+ G P+ A++
Sbjct: 4335 QLPPTHP-GTPKPQGPTLEPPPGRVSPAAAQL 4365
Score = 43.5 bits (101), Expect = 6e-04
Identities = 111/479 (23%), Positives = 154/479 (32%), Gaps = 87/479 (18%)
Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTP 243
P R S V SPG L P S H I RPGS P + P P
Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI--FRPGSYTDPYAQPPLTPRP 2387
Query: 244 PPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP 303
P P S P R L D F R P++ ++ SP L RPLS P
Sbjct: 2388 QPPPPESCCALP--PRSLPSDPFSRV--PASPQSQSSSQSP------LTPRPLSAEAFCP 2437
Query: 304 HSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGAL-HLLLAQQ 362
SP+ P DP + ++ +P L P + G+L H L
Sbjct: 2438 --SPVTPRFQSPDPYSRPPSRPQS---RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492
Query: 363 QLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP 422
A AG GE+ +P G + GT A + P
Sbjct: 2493 GFPAALPAGPA--------GELHAKVPSGQPPNFVRSPGTGAFVGT-------------P 2531
Query: 423 GRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSG 482
+ T A + +L P+ P P G + P G
Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVP--------QPGLPPPHGINSHFGP--------------G 2569
Query: 483 PLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH 542
P PQ+ +N T T + +P+ PS G LS PL PP
Sbjct: 2570 PTLGKPQS-TNYTVAT--GNFHPSGSPLGPSSGSTGESYGLS------------PLRPPS 2614
Query: 543 PQPPPHPQP--PDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600
PPP P P L H ++ + P +++ + PG+ +G S T G
Sbjct: 2615 VLPPPAPDGSLPYL-SHGASQRSGITSP----VEKREDPGTGMGSSLATAELPGTQDPGM 2669
Query: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATE----GPGSPRDAEDHSPS 655
+ E + R+R R + + R ++ A GP AE SP+
Sbjct: 2670 SGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728
Score = 42.7 bits (99), Expect = 0.001
Identities = 113/476 (23%), Positives = 154/476 (32%), Gaps = 89/476 (18%)
Query: 184 PAGHRTSPVAKISPGATLPE----SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPA 239
P R SP + P + LPE SR + SP + P + P P
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESP-------------LSPPPEESPLSPPPE 508
Query: 240 NGTPPPL------PARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLN 293
+ PL P SPPSPA E LS AS S E+P LSP + L
Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPP--EASPLSPPFEESP-LSPPPEELPTSP 565
Query: 294 RPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKAREAEAWEE------PTEL-LGLPSALAG 345
P + L P SP++P S +R +EE P E L P +
Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625
Query: 346 MQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAA 405
+ + + + + + P P + P S PE T
Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPL--PVVSRLSPPPEESPLSPPPEESPTSPP 683
Query: 406 LAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEW----------GRARGQD- 454
A+ LS P P + +D + PL+ S R+ G
Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743
Query: 455 TPKPAGQHGSLSPAAAHTA--------SPEP---------------PTQSGP-LTRSPQA 490
+P+P H S P H + SP+P P GP L+ P+
Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803
Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPL--PGSQLSLSSPGSTEDEDTGRP----LPPPHPQ 544
L P+ EE P P P + S SP S E + RP L P +
Sbjct: 804 LHLS------PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857
Query: 545 PPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600
PP P+P +P + P +EL PG E S GE P
Sbjct: 858 PPLSPRPE------KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907
Score = 39.3 bits (90), Expect = 0.012
Identities = 124/587 (21%), Positives = 208/587 (35%), Gaps = 86/587 (14%)
Query: 6 ESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRVLE 65
+ + L+++ +++ L Q +L + ++ + Q++++ QL++QQ+ + L+
Sbjct: 3892 QPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQ-----QQLQQQQQQQQ-----LQ 3941
Query: 66 NRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRL 125
+ + L + Q+ +++QQ+F+ Q Q+ L N+ L + +++V
Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQ---QQQQQQMGLLNQSRTLLSPQQQQQQQV--- 3995
Query: 126 RVLGDRPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEK 183
LG + + S P + P LL + + E HQG L
Sbjct: 3996 -ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054
Query: 184 PAGHRTSPVAKISPGATLPESR---APDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240
P T P ++ P + P PQ S QL + + Q
Sbjct: 4055 PESMATEP-GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113
Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300
G+ L + SS + + L+ S +P +MT L P+ +L RP+ +
Sbjct: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNL--LGPQQP---MLERPMQNNT 4168
Query: 301 --QSPHSSPLAPAAAPSD-----PRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353
Q P P+ + P + L+A+ + +L L+ Q +L+
Sbjct: 4169 GPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQL----RHLSPQQQQQLQA 4224
Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPTPGEML----PSL---------PVGSDSEGPENE 400
L QQ R P Q +P + L P L P+ GP +
Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284
Query: 401 GTRAALAAAG-LSGGRHTQPAGPGRAQRTEAAATQDCALDKP---LDLSEWGRARGQDTP 456
G A G LS G P P + + L P L TP
Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP 4344
Query: 457 KPAG-----QHGSLSPAAAHTA--------SPEPPTQSGPLTRSPQALS------NGTKG 497
KP G G +SPAAA A P P + T+ P+ S + G
Sbjct: 4345 KPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNG 4404
Query: 498 TRVPEQEEASTPMDPSRPLP---GSQLSLSSPGSTEDEDTGRPLPPP 541
VPE + S +P R P G+Q S + E G P+ P
Sbjct: 4405 QVVPEASQLSIKQEP-REEPCALGAQ-------SVKREANGEPIGAP 4443
Score = 37.4 bits (85), Expect = 0.045
Identities = 112/487 (22%), Positives = 162/487 (33%), Gaps = 88/487 (18%)
Query: 179 RGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGP 238
+ ++ A HR + V K + +++ D++ + LH I +PG
Sbjct: 2063 KAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPP-QPG---------- 2111
Query: 239 ANGTPPPLPARS----SPPSPAYERGLSL--DSFLRASRPSAMTHEAP-----KLSPKVD 287
A G+PPP A + SP +PA GLS D FL+ S ++P KL P+V
Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPA---GLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVP 2168
Query: 288 RLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQ 347
P L P P P A P+ P A+ +LG S Q
Sbjct: 2169 AQVPSQDPFGLAPAYP-LEPRFPTAPPTYPPYPSPTGAPAQP-----PMLGASSRPGAGQ 2222
Query: 348 DLRLEGALHLLLAQQQLRARARAGSVRPRGQP-TPGEML-PSLPVGSDSEGPENEGTRAA 405
G H PR QP TP L P P + PE+ G
Sbjct: 2223 P----GEFHT------------TPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266
Query: 406 LAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR--GQDTPKPAGQHG 463
A+ L P G +++ ++ P +G D+P G
Sbjct: 2267 KASEPL-----LSPPPFGESRKALEVKKEELGASSP----SYGPPNLGFVDSPSSGTHLG 2317
Query: 464 SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL 523
L P PLT + + G + QE P P P S +
Sbjct: 2318 GLELKT-------PDVFKAPLTPRASQVEPQSPGLGLRPQEPP--PAQALAPSPPSHPDI 2368
Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583
PGS D PL P QPPP P L P S D P S V
Sbjct: 2369 FRPGSYTDPYAQPPLTPRP-QPPP------------PESCCALPPRSLPSD----PFSRV 2411
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643
S Q++ ++S + P + + P R ++ +P + +P + R P
Sbjct: 2412 PASPQSQ-SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP-QSRDPFAPLHKP 2469
Query: 644 GSPRDAE 650
P+ E
Sbjct: 2470 PRPQPPE 2476
Score = 35.0 bits (79), Expect = 0.22
Identities = 63/267 (23%), Positives = 82/267 (30%), Gaps = 69/267 (25%)
Query: 456 PKPAGQHGSLSPAAAHTASPEPPTQSGPLTRS------------PQALSNGTKGTRVPEQ 503
P G GS PAAA T PT L+ S P S G ++P Q
Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166
Query: 504 EEASTP-MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQP------PP--------- 547
A P DP P L P T P PP+P P PP
Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPRFP-------TAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219
Query: 548 -------HPQPPDLDGHPEPSKAEVLRPESDELDE---TDTPGSEVGLSSQAEATTSTTG 597
H PP H + L+P LD ++PG G +S+ + G
Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG 2279
Query: 598 EGPECICTQEH-------GQGPPR-----KRKRASEPGDKASKKPSRGRRKLTATEG--- 642
E + + ++ GPP + G K P + LT
Sbjct: 2280 ESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE 2339
Query: 643 ---------PGSPRDAEDHSPSPNSSP 660
P P A+ +PSP S P
Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHP 2366
Score = 34.3 bits (77), Expect = 0.38
Identities = 36/133 (27%), Positives = 49/133 (36%), Gaps = 16/133 (12%)
Query: 168 EAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRA-----PDMSPQRISNQLHGTI 222
+ E G+GLR +E P +P P P S P ++P+
Sbjct: 2337 QVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC 2396
Query: 223 AVVRPGSQACPADRGPANG----------TPPPLPARSSPPSPAYERGLSLDSFLR-ASR 271
A+ + P R PA+ TP PL A + PSP R S D + R SR
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456
Query: 272 PSAMTHEAPKLSP 284
P + AP P
Sbjct: 2457 PQSRDPFAPLHKP 2469
Score = 31.6 bits (70), Expect = 2.5
Identities = 50/226 (22%), Positives = 77/226 (34%), Gaps = 23/226 (10%)
Query: 456 PKPAGQHGSLSPAAAHTASPEPPTQSGPLTRS---PQALSNGTKGTRVPEQEEASTPMDP 512
P+P GSL+ + P + P+T P+ +G+ EQEE P+ P
Sbjct: 1135 PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194
Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHP---QPPPH-----PQPPDLDGHPEPSKAE 564
+ P ++ + D P P P P + P++ E
Sbjct: 1195 TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDE 1254
Query: 565 -VLRPESDELDETD-----TPGSEV-GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK 617
LR +D L ETD G+ + G ++ E + I P R+R
Sbjct: 1255 GSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRP 1314
Query: 618 RASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEE 663
R G + RGR +L +T D SP+ EE
Sbjct: 1315 RGGAHGGR-----GRGRARLKSTASSIETLVVADIDSSPSKEEEEE 1355
Score = 30.0 bits (66), Expect = 7.1
Identities = 66/252 (26%), Positives = 96/252 (38%), Gaps = 54/252 (21%)
Query: 131 RPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPP-GGHEEAEEDHQGVGLRGEEKPAGHRT 189
RP P A + D S L+ GG +A ++ P G ++ Q + +++ A T
Sbjct: 2774 RPPPPATPSSMDVNSRQLV---GGSQAFYQRAPYPGSLPLQQQQQQLW---QQQQATAAT 2827
Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPA---------- 239
S + + A P + P++ Q + + L G + + P GPA
Sbjct: 2828 S--MRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885
Query: 240 -----NGTP-----PPLPARSSPPS-------PAYERGLSLDSFLRASRPSAMTHEAPKL 282
GTP PP R P S P RGL++ S L +PSA AP+L
Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAV-SGLPPQKPSA--PPAPEL 2942
Query: 283 SPKV------------DRLCLLNR-PLSLHLQSPHSSPLAPAAAP-SDPRL-QDLKAREA 327
+ + L L+NR P S L P+ L P DP L D A +A
Sbjct: 2943 NNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKA 3002
Query: 328 EAWEEPTELLGL 339
+E LGL
Sbjct: 3003 LEDDEELAHLGL 3014
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 53.9 bits (128), Expect = 5e-07
Identities = 112/494 (22%), Positives = 151/494 (30%), Gaps = 87/494 (17%)
Query: 134 PRAKEGTSDPPSP---LLLPSPGGW--KAITEKPPGGHEEAEEDHQG------VGLR--- 179
P A G + PP P L SPG ++T + A D G +G R
Sbjct: 601 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660
Query: 180 --GEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRG 237
+ PA P SP P AP + P +S + P + P
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720
Query: 238 PA---NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294
P + +PPP P S P P + +P + EAP S +
Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTK-----------KPEVVV-EAPSASETAEE------ 762
Query: 295 PLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354
P P P P P QDL + EE + P G+
Sbjct: 763 --------PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP------SGS 808
Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSL-----------------PVG-SDSEG 396
L+ + + A A ++P G P P P+ PVG S G
Sbjct: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGG 868
Query: 397 PENEGTRAALA-----------AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLS 445
P E A L + G GG T GP Q+ A A P S
Sbjct: 869 PPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSS 928
Query: 446 EWGRARGQDTPKPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ 503
A A G S P A P PP P + + S G++ ++
Sbjct: 929 GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPP--QSPASTASFIFSKGSRKLQLERP 986
Query: 504 EEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKA 563
T D R L S+S + PPP + P PP P +A
Sbjct: 987 VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPP--PASPSYPRA 1044
Query: 564 EVL-RPESDELDET 576
E L P ++ L T
Sbjct: 1045 EPLTAPPTNGLPHT 1058
Score = 53.1 bits (126), Expect = 8e-07
Identities = 117/495 (23%), Positives = 167/495 (33%), Gaps = 86/495 (17%)
Query: 224 VVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS 283
+ RP S A P G A P PA S P Y L P A+ L
Sbjct: 317 LTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATY---------LSKLIPHAV------LP 361
Query: 284 PKVDRLCLLNRPL------SLHLQSPHS-SPLAPAAAPSDPRLQDLK-AREAEAWEEPTE 335
P VD + L L SLH SP S L ++ S P+ + + ++ W
Sbjct: 362 PTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQS 421
Query: 336 LLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE 395
+ ++ L +G ++ Q + + SV P Q G PS GS +E
Sbjct: 422 S---DTIVSDGSTLSSKGG-----SEGQPESSTASNSVVPPPQGGSGRGSPS--GGSTAE 471
Query: 396 GPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCAL-DKPLDLSEWGRARGQ- 453
+ R++ +G S P +RT + + A+ D PL L + Q
Sbjct: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP 531
Query: 454 DTPKPAGQHGSLSPAAAHTASPEP---------------PTQSGPLTRSPQALSNGTKGT 498
P+P GS AA P P P +S T SP + + GT
Sbjct: 532 QLPRPPTTGGSEGAGAA-PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590
Query: 499 -RVPEQEEASTPMDPSR---PLPGSQLSLSSPGSTEDED-------TGRPLP-------- 539
+P + A P P + P P SL SPG++ + P P
Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650
Query: 540 ----------PPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQ 588
PPHP+ P P PP P P+ + P P S S Q
Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAV-----VPGPVSTTDASPQ 705
Query: 589 AEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRD 648
+ T TT + Q PP + P +KKP +A+E P
Sbjct: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765
Query: 649 AEDHSPSPNSSPWEE 663
+ P P +P E+
Sbjct: 766 DPNWPPPPPPAPEEQ 780
Score = 45.1 bits (105), Expect = 2e-04
Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 11/185 (5%)
Query: 467 PAAAHTASPE-PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSS 525
P + ASP+ PPT LT ++ + P + P P P + S
Sbjct: 696 PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755
Query: 526 PGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKA--EVLRPESDELDETDTPGSEV 583
T +E P PP P P P Q + P P +A V PE GS
Sbjct: 756 ASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE-----PAGPSGSPE 810
Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643
+SS A +++S T + + + PP +S PG A K P + + ++G
Sbjct: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVA-KLPQ--KEPVGCSKGG 867
Query: 644 GSPRD 648
G PR+
Sbjct: 868 GPPRE 872
Score = 30.8 bits (68), Expect = 4.2
Identities = 63/257 (24%), Positives = 86/257 (33%), Gaps = 53/257 (20%)
Query: 139 GTSDPPSPLLLPSP-----GGWKAITEKPPGGHEEA----EEDH----------QGVGLR 179
G+ DPP P+P G + +K P G + ED Q V LR
Sbjct: 831 GSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLR 890
Query: 180 GEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRI-SNQLHGTI-------AVVRPGSQA 231
P G T + +P L + + SP S+ LH + A S A
Sbjct: 891 SVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSA 950
Query: 232 CPADRGPANGTPPPLPARSS---------------PPSPAYERGL--SLDSFLRA---SR 271
P A PP PA ++ P SP + L +L + LR+ R
Sbjct: 951 QPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQR 1010
Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAE--- 328
P ++PK P V R + P P + PL P QD RE
Sbjct: 1011 PPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENG 1070
Query: 329 ---AWEEPTELLGLPSA 342
P E +GLP +
Sbjct: 1071 GVLQLVGPEEKMGLPGS 1087
>gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo
sapiens]
Length = 247
Score = 53.9 bits (128), Expect = 5e-07
Identities = 58/232 (25%), Positives = 89/232 (38%), Gaps = 27/232 (11%)
Query: 336 LLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSD-S 394
LL L SA + +D+ E +L L+ + + R R + G+ R P PG+ P G + S
Sbjct: 10 LLALSSAESSSEDVSQEESLFLISGKPEGR-RPQGGNQPQRPPPPPGKPQGPPPQGGNQS 68
Query: 395 EGPENEGTRAALAAAGLSGGRHTQ--PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG 452
+GP + GG +Q P PG+ +R G +
Sbjct: 69 QGPPPPPGKPE--GRPPQGGNQSQGPPPHPGKPERPPPQ----------------GGNQS 110
Query: 453 QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDP 512
Q TP P G+ P + + PP P PQ + P + E P +
Sbjct: 111 QGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEG 170
Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ-PPDLDGHPEPSKA 563
++ S+ + S PG + P P PP PQ PP G+P+ +A
Sbjct: 171 NK----SRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQA 218
Score = 42.7 bits (99), Expect = 0.001
Identities = 50/215 (23%), Positives = 71/215 (33%), Gaps = 25/215 (11%)
Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499
KP G + Q P P G+ P + + PP P PQ N ++GT
Sbjct: 56 KPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQG-GNQSQGTP 114
Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE 559
P P P RP P + RP PPP P PQ + P
Sbjct: 115 PP-------PGKPERPPPQG-----------GNQSHRPPPPPGKPERPPPQGGNQSQGPP 156
Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA 619
P + P E +++ + S G + + G P+ QGPP
Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPG---KPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213
Query: 620 SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSP 654
+P + KP + +G PR A+ P
Sbjct: 214 QQPQAPPAGKP---QGPPPPPQGGRPPRPAQGQQP 245
Score = 37.7 bits (86), Expect = 0.034
Identities = 37/159 (23%), Positives = 49/159 (30%), Gaps = 22/159 (13%)
Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ------------PPPH 548
PE P RP P P ++ G P PP P+ PPPH
Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPH 95
Query: 549 PQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEH 608
P P+ P P + + + P + G S E P +
Sbjct: 96 PGKPE---RPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ- 151
Query: 609 GQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPR 647
QGPP PG P G + +A PG P+
Sbjct: 152 SQGPPPH------PGKPEGPPPQEGNKSRSARSPPGKPQ 184
Score = 35.0 bits (79), Expect = 0.22
Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 22/145 (15%)
Query: 130 DRPKPRA---KEGTSDPPSPLLLPSP-GGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPA 185
+RP P+ +GT PP P P GG ++ PP G E G +G
Sbjct: 100 ERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHP 159
Query: 186 GHRTSPVAKI---SPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS-----------QA 231
G P + S A P + P PQ+ N+ G +P QA
Sbjct: 160 GKPEGPPPQEGNKSRSARSPPGK-PQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQA 218
Query: 232 CPADRGPANGTPPPLPARSSPPSPA 256
PA G G PPP P PP PA
Sbjct: 219 PPA--GKPQGPPPP-PQGGRPPRPA 240
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.308 0.128 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,309,307
Number of Sequences: 37866
Number of extensions: 2520507
Number of successful extensions: 30191
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 381
Number of HSP's successfully gapped in prelim test: 2060
Number of HSP's that attempted gapping in prelim test: 15519
Number of HSP's gapped (non-prelim): 10803
length of query: 664
length of database: 18,247,518
effective HSP length: 109
effective length of query: 555
effective length of database: 14,120,124
effective search space: 7836668820
effective search space used: 7836668820
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.