BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|24308394 hypothetical protein LOC140893 [Homo sapiens] (664 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|24308394 hypothetical protein LOC140893 [Homo sapiens] 1348 0.0 gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap... 138 2e-32 gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 138 2e-32 gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 138 2e-32 gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 75 2e-13 gi|163965366 nascent polypeptide-associated complex alpha subuni... 74 6e-13 gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 71 3e-12 gi|210032580 SET domain containing 1B [Homo sapiens] 66 1e-10 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 64 4e-10 gi|150170670 piccolo isoform 2 [Homo sapiens] 62 2e-09 gi|150378539 piccolo isoform 1 [Homo sapiens] 62 2e-09 gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 62 2e-09 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 59 1e-08 gi|188536004 zinc finger protein 469 [Homo sapiens] 59 2e-08 gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sap... 58 3e-08 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 57 5e-08 gi|91208420 bassoon protein [Homo sapiens] 56 9e-08 gi|50428935 BPY2 interacting protein 1 [Homo sapiens] 56 9e-08 gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 56 1e-07 gi|146219832 myosin light chain kinase 3 [Homo sapiens] 56 1e-07 gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] 55 2e-07 gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 55 2e-07 gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] 55 3e-07 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 54 5e-07 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 54 5e-07 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 54 5e-07 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 54 5e-07 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 54 5e-07 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 54 5e-07 gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Ho... 54 5e-07 >gi|24308394 hypothetical protein LOC140893 [Homo sapiens] Length = 664 Score = 1348 bits (3489), Expect = 0.0 Identities = 664/664 (100%), Positives = 664/664 (100%) Query: 1 MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN 60 MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN Sbjct: 1 MESFMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKEN 60 Query: 61 LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE 120 LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE Sbjct: 61 LRVLENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKE 120 Query: 121 EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG 180 EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG Sbjct: 121 EVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRG 180 Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN Sbjct: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL Sbjct: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300 Query: 301 QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA 360 QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA Sbjct: 301 QSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLA 360 Query: 361 QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA 420 QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA Sbjct: 361 QQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPA 420 Query: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ Sbjct: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480 Query: 481 SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP 540 SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP Sbjct: 481 SGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPP 540 Query: 541 PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600 PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP Sbjct: 541 PHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600 Query: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP Sbjct: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 Query: 661 WEET 664 WEET Sbjct: 661 WEET 664 >gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sapiens] Length = 867 Score = 138 bits (347), Expect = 2e-32 Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%) Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63 F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79 Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123 LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++ Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139 Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 + ++ D+ A+ E P SP+ S G + K E+ H Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191 >gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sapiens] Length = 897 Score = 138 bits (347), Expect = 2e-32 Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%) Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63 F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79 Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123 LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++ Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139 Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 + ++ D+ A+ E P SP+ S G + K E+ H Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191 >gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapiens] Length = 897 Score = 138 bits (347), Expect = 2e-32 Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%) Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63 F + +LKE H++EV GLQ K+ +L ER DAQR+EE F+KN QLREQQK L E ++V Sbjct: 20 FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79 Query: 64 LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123 LE+RLRAGLCDRC VT+E RK+QQEFE+ QNL+ I L NE N L+EEN+ L E+++ Sbjct: 80 LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139 Query: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 + ++ D+ A+ E P SP+ S G + K E+ H Sbjct: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191 >gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] Length = 904 Score = 75.1 bits (183), Expect = 2e-13 Identities = 149/693 (21%), Positives = 239/693 (34%), Gaps = 88/693 (12%) Query: 4 FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQ-RIEELFSKNHQLREQQKTLKENLR 62 FM L L ++ + G+ + LEL E + Q E+L S Q ++ K KE Sbjct: 101 FMGELWPLLLSAQENIAGIPSAFLELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKE 160 Query: 63 VLENRLRAGLCDRCMVTQELARKRQ-----QEFESSHLQNLQRIFILTNEMNGLKEENET 117 + R ++ + +R+ +E + SH ++ + + +++ +T Sbjct: 161 SSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKT 220 Query: 118 LKEEVKRLRVLGDRPKPRAKEGTSD---PPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQ 174 E+ V P + TSD P P +P P K P + ++++ + Sbjct: 221 --PELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEP--------KEPSPEKNSKKEKE 270 Query: 175 GVGLRGEEKPAGHRTSPVAKISPGATLPE----SRAPDMSPQRISNQLHGTIAVVRPGSQ 230 R + S SP T P SR+ SP+R RP + Sbjct: 271 KEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRR------------RPSPR 318 Query: 231 ACPADRG---PANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVD 287 P+ R P PPP RS P R + S +S S+ + PK PK Sbjct: 319 RRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378 Query: 288 RLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQ 347 + P SP +SP PS P K R + P + + + Sbjct: 379 S----SPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPT---PQQSNRTRKSRVSVS 431 Query: 348 DLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALA 407 R G + + + + S P +P E+ SE E++G + A A Sbjct: 432 PGRTSGKV------TKHKGTEKRESPSPAPKPRKVEL---------SESEEDKGGKMAAA 476 Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKP----LDLSEWGRARGQD-----TPKP 458 + ++ + + +++++D ++P + E GR R +P P Sbjct: 477 DSVQQRRQYRRQNQQSSSDSGSSSSSED---ERPKRSHVKNGEVGRRRRHSPSRSASPSP 533 Query: 459 AGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPM------DP 512 + SP SP PP + SP + P + +P P Sbjct: 534 RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP 593 Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK---AEVLRPE 569 R P Q S P T P PPP + P P P H P K + V + Sbjct: 594 RRYSPPIQRRYS-PSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRR 652 Query: 570 SDELDETDTPGSEVGLSSQAEATTSTT---GEGPECICTQEHGQGPPRKRKRASEPGDKA 626 S L GS S++ + P Q PP +R +S P + Sbjct: 653 SPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQ 712 Query: 627 SKKPS-RGRRKLTATEGPGSPRDAEDHSPSPNS 658 S PS R R+++ T P + A SPSP S Sbjct: 713 SPSPSTRPIRRVSRTPEPKKIKKAA--SPSPQS 743 Score = 48.9 bits (115), Expect = 1e-05 Identities = 51/216 (23%), Positives = 83/216 (38%), Gaps = 21/216 (9%) Query: 464 SLSPAAAHTASPEPPTQSGPL--------TRSPQALSNGTKGTRVPEQEEASTPMDPSRP 515 S SP + SP P +S P+ +RSP+ + + PE++E TP Sbjct: 169 SRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE-KTP-----E 222 Query: 516 LPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK-AEVLRPESDELD 574 LP + + P E T L P P+P P P+ P + + + K E RP S Sbjct: 223 LPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS 282 Query: 575 ETDT---PGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRK---RKRASEPGDKASK 628 ++ + S + + + P + P R+ R+ P + S+ Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSR 342 Query: 629 KPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET 664 P R RR+ +A+ S + S SP P + T Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRT 378 Score = 38.1 bits (87), Expect = 0.026 Identities = 47/190 (24%), Positives = 69/190 (36%), Gaps = 38/190 (20%) Query: 455 TPKPAGQHG-SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513 +P+P +H S P A T+S PP + G + SPQ + + TR P + + TP +P Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGA-SSSPQRRQSPSPSTR-PIRRVSRTP-EPK 731 Query: 514 R------PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE-PSKAEVL 566 + P P S +SS S PP P P Q P + P P K Sbjct: 732 KIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK---- 787 Query: 567 RPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA 626 +A + T P QE G +K+K DK Sbjct: 788 -----------------------KAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKK 824 Query: 627 SKKPSRGRRK 636 KK + +++ Sbjct: 825 HKKHKKHKKE 834 Score = 36.2 bits (82), Expect = 0.100 Identities = 52/234 (22%), Positives = 72/234 (30%), Gaps = 38/234 (16%) Query: 457 KPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPL 516 +P+ Q + + PEP + P SP+ K ++ +++E + P SR Sbjct: 232 EPSVQEATSTSDILKVPKPEPIPE--PKEPSPE------KNSKKEKEKEKTRPRSRSRSK 283 Query: 517 PGSQLSLSSPGSTEDE-----------DTGRPLPPPHPQP----PPHPQPPDLDGHPEPS 561 S+ SP T RP P P P PP PP S Sbjct: 284 SRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRS 343 Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 R S L + + S S + T P PPR+R R S Sbjct: 344 PVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSP 403 Query: 622 PGDKASK-------KPSRGRRKLTATEGPGSPR--------DAEDHSPSPNSSP 660 P K + S RK + PG + SPSP P Sbjct: 404 PATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 73.6 bits (179), Expect = 6e-13 Identities = 138/577 (23%), Positives = 185/577 (32%), Gaps = 80/577 (13%) Query: 129 GDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188 G + P A + PPSP P+P A+T P +GV L +E P Sbjct: 845 GSKDSP-ATTHSPTPPSPKGAPTPS---AVTPLSP----------KGVTLPPKETP---- 886 Query: 189 TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANG-TPP--- 244 T V + P + AP +P A P + PA P TPP Sbjct: 887 TPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT 946 Query: 245 ----------------PLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDR 288 P P ++PPSP + G + S A P A T +PK P Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSP--KGGPATPSPKGAPTPPAATPPSPKGGPATPS 1004 Query: 289 LCLLNRPLSLHLQSPHSSPLA----------PAAAPSDPRLQDLKAREAEAWEEPTELLG 338 P ++ SP SP A PAA P P+ A T Sbjct: 1005 PKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPK-GSPAATPLPKGAPTTPAAT 1063 Query: 339 LPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGP- 397 LPS G L+GA A + + P+G P P P P G + P Sbjct: 1064 LPSPKGGPATPSLKGA-PTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122 Query: 398 ENEGTRAALAAAGLSGGRHTQP--AGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDT 455 + T A GG T P P T + A P A Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA---TP 1179 Query: 456 PKPAGQHGSLSPAAAHT--ASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513 P P G + SP A T A+ P + G T SP+ T + +TP Sbjct: 1180 PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG 1239 Query: 514 RPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQP-PPHPQPPDLDG------HPEPSKAEV 565 P ++P +T G P PPP P PP PP L G H V Sbjct: 1240 AP--------TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291 Query: 566 LRPESDELDETDTP--GSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPG 623 + P S + +P G+ ++ + + G P PP + + P Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351 Query: 624 DKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 S K G ++ EGP P H P +P Sbjct: 1352 TTPSSK--GGPTTPSSKEGPTPPAATPSHKGGPAMTP 1386 Score = 70.1 bits (170), Expect = 6e-12 Identities = 138/561 (24%), Positives = 187/561 (33%), Gaps = 61/561 (10%) Query: 134 PRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193 P + +G PSP P+P A+T P G A +G PA T P Sbjct: 993 PPSPKGGPATPSPKGAPTP---PAVTPPSPKGSPAATPFPKGAST----PPAA--TPPSP 1043 Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPA------DRGPANGTP--PP 245 K SP AT AP + + G G+ PA GPA +P P Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103 Query: 246 LPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPK-----LSPKVDRLCLLNRPLS--- 297 +P ++PPSP + GL+ A A T +PK PK P S Sbjct: 1104 MPPAATPPSP--KGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161 Query: 298 -LHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALH 356 L P +P PAA P P+ A + T PS G+ +GA Sbjct: 1162 GLATPPPKGAPTTPAATPPSPK--GGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA-P 1218 Query: 357 LLLAQQQLRARARAGSVRPRGQP-TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGR 415 A + + P+G P TP PS G + P+ T A L GG Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278 Query: 416 HTQP--AGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHT- 472 T P P A T + A P A P P G G+ P A T Sbjct: 1279 ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAA---TPPSPKGSPGTPPPKGAPTP 1335 Query: 473 ASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP------------MDPSRPLPGSQ 520 + PP+ G T P + G P +E TP M P P G Sbjct: 1336 PAVTPPSPKGTPT-LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394 Query: 521 LSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPG 580 + S + + T + P P+ P P +G PSK ++ P + P Sbjct: 1395 IP-----SPKGDPTSPAVIPLSPKKAP-ATPVTREGAATPSKGDLTPPAVTPVSLKKAPA 1448 Query: 581 SEVGLSSQAEATTSTTGEGPECICTQEHGQGPPR-KRKRASEPGDKASKKPSRGRRKLTA 639 + AT S+ G+ T + PP K+ S KA P+ Sbjct: 1449 TSA--PKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLP 1506 Query: 640 TEGPGSPRDAEDHSPSPNSSP 660 P SP++ +PS P Sbjct: 1507 AVIPSSPKEV-PATPSSRRDP 1526 Score = 51.6 bits (122), Expect = 2e-06 Identities = 108/459 (23%), Positives = 145/459 (31%), Gaps = 67/459 (14%) Query: 221 TIAVVRPGSQACPADRGPANGTPP-----------------PLPARSSPPSPAYERGLSL 263 T+ +V S+ CP P N P LP +PP G+S Sbjct: 697 TLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISH 756 Query: 264 DSFLR--ASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQD 321 S L AS P E P L+ SP SPL + +P R Sbjct: 757 TSALAPVASSPK----ECPTEDSGASATASSKGTLTYLADSP--SPLGVSVSPQTKRPPT 810 Query: 322 LKAREAEAWEEPTELLGLPSALAGMQDLRL-EGALHLLLAQQQLRARARAGSVRPRGQPT 380 K T + L S ++ ++ L E +L ++ P+G PT Sbjct: 811 KKGSAGP----DTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866 Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440 P + P P G P+ T + + G PA P Q + T Sbjct: 867 PSAVTPLSPKGVTLP-PKETPTPSVVNLPFPKEG----PATPAPKQAPALSMTSSSP--- 918 Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHT--ASPEPPTQSGPLTRSPQALSNGTKGT 498 + + TP P G S SP A T A+ P + GP T SP+ T Sbjct: 919 ---------KKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAAT 969 Query: 499 RVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQP-PPHPQPPDLDG 556 + +TP P P P +T G P P P P PP PP Sbjct: 970 PPSPKGGPATPSPKGAPTP--------PAATPPSPKGGPATPSPKGAPTPPAVTPPS--- 1018 Query: 557 HPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKR 616 P+ S A P+ TP S G AT G T +G P Sbjct: 1019 -PKGSPAATPFPKGASTPPAATPPSPKG---SPAATPLPKGAPTTPAATLPSPKGGPATP 1074 Query: 617 KRASEPGDKASKKPS-RGRRKLTATEGPGSPRDAEDHSP 654 P A+ PS +G + +G P A SP Sbjct: 1075 SLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSP 1113 Score = 50.4 bits (119), Expect = 5e-06 Identities = 119/532 (22%), Positives = 185/532 (34%), Gaps = 83/532 (15%) Query: 132 PKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSP 191 P P+ +S P P+P G + P +E R P Sbjct: 1479 PAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSS------------RRDP 1526 Query: 192 VAKISPGATLPESRAP-DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR- 249 +A P ATL + P ++P+ A++ P + PA TP PA Sbjct: 1527 IA---PTATLLSKKTPATLAPKE---------ALIPPAMTVPSPKKTPAIPTPKEAPATP 1574 Query: 250 -----SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPH 304 SSPP+ S P A+T +PK +P + + +P Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634 Query: 305 SSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLG--LPSALAGMQDLRLEGALHLLLAQQ 362 +P +P PS L+D A T +G +P A G+ + AL +L Sbjct: 1635 GTPTSPPVTPSS--LKDSPTSPASV----TCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688 Query: 363 Q------LRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRH 416 + A R G + T + P + S+GP + A L + Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKT 1748 Query: 417 TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE 476 + + + A + A PL + + + PKP +A+ +A+P Sbjct: 1749 AKGKDASHSPKGPLAPPESKA-STPLTAAAFEKV----LPKPE--------SASVSAAPS 1795 Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536 PP S PL SP T P+Q+ P P L S S P + DED Sbjct: 1796 PPV-SLPLAPSPVP-------TLPPKQQ--FLPSSPGLVLE----SPSKPLAPADEDELL 1841 Query: 537 PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRP---------ESDELDETDTPGSEVGLSS 587 PL PP P P L P P A + P ++++ T++ E Sbjct: 1842 PLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPEL 1901 Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSR-GRRKLT 638 + + +T T + + E + P K K+ S KA K S+ G R++T Sbjct: 1902 EEQDSTQATTQQAQLAAAAEIDEEPVSKAKQ-SRSEKKARKAMSKLGLRQVT 1952 Score = 29.6 bits (65), Expect = 9.3 Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 7/121 (5%) Query: 197 PGATLPE--SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254 PG TLP S AP P +NQ + S P + + LP ++P + Sbjct: 41 PGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPF-PQSSSGTALPLGTAPEA 99 Query: 255 PAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAP 314 P + L P+A+ +P ++P + + PL+L +PHS + A P Sbjct: 100 PTFLPNLIGPPI----SPAALALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPP 155 Query: 315 S 315 + Sbjct: 156 N 156 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 71.2 bits (173), Expect = 3e-12 Identities = 149/575 (25%), Positives = 193/575 (33%), Gaps = 110/575 (19%) Query: 131 RPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188 RP P A+ PP+ P S + TE P G GL ++PA Sbjct: 182 RPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAARRRPSA---GGGL---QRPASRS 232 Query: 189 TSPVAK--ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS------QACPADRGPAN 240 S A SP + P +R +P S + +RP A PA GP + Sbjct: 233 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA-LGPLS 291 Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPL--SL 298 +P P+ S+PPSP ++ PS T +P +P L P + Sbjct: 292 SSPLATPSPSAPPSP-------------SAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338 Query: 299 H--LQSPHSSPLA--PAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354 H L SP SPLA P AP L L+A + P L PS A A Sbjct: 339 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPN-----ALA 393 Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGG 414 +HLL A P+P P P S P T + A L+ Sbjct: 394 VHLLQAPFS-------------PPPSPPVQAPFSPPASPPVSP--SATPPSQAPPSLAAP 438 Query: 415 RHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG-------------QDTPKPAGQ 461 P P + +AT PL A+ Q P P Sbjct: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS 498 Query: 462 ---HGSLSPAAAHTASP--EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR-- 514 SP+A+ SP PP Q+ P+ +P +VP AS + R Sbjct: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL--------LQVPPSPPASPTLQAPRRP 550 Query: 515 PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELD 574 P PG S+S P T G P PPP P PDL GH S + PE Sbjct: 551 PTPGPDTSVSGPRLTLALAPGPP-PPPSRSPSSTLSGPDLAGH---SSSATSTPE----- 601 Query: 575 ETDTPGSEVGLSSQAEATTSTTGEGPEC-ICTQEHGQGPPRKRKRASEPGDKASKKPSRG 633 + G + G A A+ E C G PP + A PG P+ G Sbjct: 602 --ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGA--PGAPLPWPPATG 657 Query: 634 RRK------LTATEGPGSPRDAE---DHSPSPNSS 659 + TEGP S A D PSP +S Sbjct: 658 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 692 Score = 54.7 bits (130), Expect = 3e-07 Identities = 129/552 (23%), Positives = 171/552 (30%), Gaps = 86/552 (15%) Query: 117 TLKEEVKRLRVLGDRPKPRAKEGTSDPP----SPLLLPSPGGWKAITEKPPGGHEEAEED 172 T+ E R P + G PP SP + SPG T P G + Sbjct: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 Query: 173 HQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQA- 231 + RG+ A R++ A + P P + R S + + RP A Sbjct: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 Query: 232 -CPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS------- 283 P GP ++ PSPA R S L+ +++ A LS Sbjct: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248 Query: 284 --------------PKVDRLCLLNRP--------LSLHLQSPHSSPLA---PAAAPS--- 315 PK L L P + L SSPLA P+A PS Sbjct: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308 Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRP 375 P LQ L + A + T LG P+ A H L L A P Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTL----------QATHSFLPSPPLSPLATPPPQAP 358 Query: 376 RGQPTPGEMLPSLPVGSDSEGP---ENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAA 432 P P P S P + ALA L P+ P +A + A+ Sbjct: 359 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 418 Query: 433 TQDCALDKPLDLSEWGRARG--QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490 P + A Q P P SP + +A+P PP PL P Sbjct: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMSPSATP-PPQAPPPLAAPPLQ 472 Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL--SSPGSTEDEDTGRPLPPPHPQPPPH 548 L+ + P Q + P + LP S +P S PL P PQ PP Sbjct: 473 LA------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526 Query: 549 PQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEH 608 P L P P + L+ TPG + +S GP Sbjct: 527 LAAPLLQVPPSPPASPTLQAPR----RPPTPGPDTSVS------------GPRLTLALAP 570 Query: 609 GQGPPRKRKRAS 620 G PP R +S Sbjct: 571 GPPPPPSRSPSS 582 Score = 49.7 bits (117), Expect = 9e-06 Identities = 94/363 (25%), Positives = 115/363 (31%), Gaps = 85/363 (23%) Query: 365 RARARAGSV-RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG---------- 413 R +A+AG+ R PG + P P P L AAG G Sbjct: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGG 64 Query: 414 -GRHTQP-----AGPGRAQRTEAAATQDCALD----KPLDLSEWGRARGQDTPKPAGQHG 463 G T P AGP R R A+ + A P +S GRA G P P GQ G Sbjct: 65 IGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124 Query: 464 ---------------------SLSPAAAH-TASPEPPTQSGPLTRSPQALSNG------- 494 +LS A T+ P P T S + R +A Sbjct: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184 Query: 495 --------TKGTR--VPEQEEAST--PMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH 542 T+G R V E ST P +R P + L P S + PL P Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244 Query: 543 PQPPPHPQPPDLDGH---PEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEG 599 P P H P+P + LRP D + LSS AT S + Sbjct: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS--- 301 Query: 600 PECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHS--PSPN 657 PP + S P S+ AT GSP HS PSP Sbjct: 302 -----APPSPSAPPSLQTLPSPPATPPSQ----------ATTSLGSPTLQATHSFLPSPP 346 Query: 658 SSP 660 SP Sbjct: 347 LSP 349 >gi|210032580 SET domain containing 1B [Homo sapiens] Length = 1923 Score = 65.9 bits (159), Expect = 1e-10 Identities = 128/518 (24%), Positives = 184/518 (35%), Gaps = 88/518 (16%) Query: 155 WKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD-----M 209 +++ +E P E+ EE + EE+ VA+ S + PE D + Sbjct: 1121 FESSSESSPSSSEDEEEV-----VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAAL 1175 Query: 210 SPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS----PAYERGLSLD- 264 +P + G V ++A + P+ PPLP P+ P E GLS + Sbjct: 1176 APGAPAVDSLGMEEEVDIETEAVAPEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEG 1235 Query: 265 SFLRASRPSAMTHEA-PKLSPK--------VDRLCLLNRPLSLHLQSPHSSPLAPAAAPS 315 + L + P A EA P LSP+ V+ + PL L P P P + P Sbjct: 1236 AMLLSPEPPAKEVEARPPLSPERAPEHDLEVEPEPPMMLPLPLQPPLPPPRPPRPPSPPP 1295 Query: 316 DPRLQDLK----AREAEAWEEPTELLGLPSALAGMQDLRLE------------GALHLLL 359 +P D E A + P GL +LA Q G+ L L Sbjct: 1296 EPETTDASHPSVPPEPLAEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSL 1355 Query: 360 AQQQLRAR-----ARAGSVRPRGQP-TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG 413 + Q+ A + S+ G P TPG P S+ GP L L Sbjct: 1356 SSPQVPGSPFSYPAPSPSLSSGGLPRTPGRDFSFTPTFSEPSGP------LLLPVCPLPT 1409 Query: 414 GRHTQPAGP-GRAQRTEAAATQDCALDKPLDLSEWGRARGQ---DTPKPAGQHGSLS--- 466 GR + +GP E L PL L+ R Q TP P L+ Sbjct: 1410 GRRDERSGPLASPVLLETGLPLPLPLPLPLPLALPAVLRAQARAPTPLPPLLPAPLASCP 1469 Query: 467 ------PAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQ 520 P + P + GPL R P + G + +P Q + TP+ PS P + Sbjct: 1470 PPMKRKPGRPRRSPPSMLSLDGPLVRPPAGAALGRELLLLPGQPQ--TPVFPSTHDPRTV 1527 Query: 521 LSLSSPGSTEDEDTGRPLPPPH--PQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDT 578 + + + G P PPP PQPPP P PP + EP+K ++ E Sbjct: 1528 -------TLDFRNAGIPAPPPPLPPQPPPPPPPPPV----EPTKLPFKELDNQWPSEAIP 1576 Query: 579 PGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKR 616 PG T E E ++ + PP+KR Sbjct: 1577 PG--------PRGRDEVTEEYMELAKSRGPWRRPPKKR 1606 Score = 51.6 bits (122), Expect = 2e-06 Identities = 93/396 (23%), Positives = 132/396 (33%), Gaps = 73/396 (18%) Query: 211 PQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRAS 270 P + Q T A P +QA PA + +P P PP P E + +F + Sbjct: 367 PFKAQPQDSATFAHTPPPAQATPAPGFKSAFSPYQTPVAHFPPPP--EEPTATAAF--GA 422 Query: 271 RPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAW 330 R S AP P L L + P + P P P D +L R W Sbjct: 423 RDSGEFRRAPAPPP-------LPPAEPLAKEKPGTPPGPP---PPDTNSMELGGRPTFGW 472 Query: 331 E-EPTELLGLP---SALAGMQDLR--LEGALHLLLAQQQ-----LRARARAGSVRPRGQP 379 EP + G P S+ AG + L+ + +LL +Q+ LR ++ G P Sbjct: 473 SPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQMEGSP 532 Query: 380 ---TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDC 436 + ++ P P G++S+ P G + +G P D Sbjct: 533 ISSSSSQLSPLAPFGTNSQ-PGFRGPTPPSSRPSSTGLEDISPT-----------PLPDS 580 Query: 437 ALDKPLDLSEWGRARGQD-TPKPAGQHGSLSPAAAHTASPEPPTQ--------------- 480 D+ LDL R + P PAG + A PT Sbjct: 581 DEDEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDME 640 Query: 481 -------SGPLTRS----PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGST 529 S P+T + P ++ G P + P+ P P L P Sbjct: 641 ISDDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFP----PLPPPPPP 696 Query: 530 EDEDTGRPLPPPHPQPPPHPQP--PDLDGHPEPSKA 563 G P+PPP P PPP P P P + P P A Sbjct: 697 PPPQPGFPMPPPLPPPPPPPPPAHPAVTVPPPPLPA 732 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 63.9 bits (154), Expect = 4e-10 Identities = 153/592 (25%), Positives = 196/592 (33%), Gaps = 114/592 (19%) Query: 131 RPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188 RP P A+ PP+ P S + TE P G GL ++PA Sbjct: 191 RPAPSARPR---PPTEGPRKSVSSASEHSTTEPSPAARRRPSA---GGGL---QRPASRS 241 Query: 189 TSPVAK--ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPA-DRGPANG---- 241 S A SP + P +R +P S + +RP P D PA G Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Query: 242 ----TPPP---LPARSSPPSPAYERGLSLDSFLR----------ASRPSAMTHEAPKLSP 284 TP P L +++ P PA SL L ++ PS T +P +P Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361 Query: 285 KVDRLCLLNRPL--SLH--LQSPHSSPLA--PAAAPSDPRLQDLKAREAEAWEEPTELLG 338 L P + H L SP SPLA P AP L L+A + P L Sbjct: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421 Query: 339 LPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPE 398 PS A A+HLL A P+P P P S P Sbjct: 422 TPSPQAPNAL-----AVHLLQAPFS-------------PPPSPPVQAPFSPPASPPVSPS 463 Query: 399 NEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKP 458 T + A L+ P P + +AT PL A+ P Sbjct: 464 --ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP 521 Query: 459 A-----------------GQHGSLSPAAAHTASP--EPPTQSGPLTRSPQALSNGTKGTR 499 A GQ SP+A+ SP PP Q+ P+ +P + Sbjct: 522 ALATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPPPQAPPVLAAPLL--------Q 572 Query: 500 VPEQEEASTPMDPSR--PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH 557 VP AS + R P PG S+S P T G P PPP P PDL GH Sbjct: 573 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRSPSSTLSGPDLAGH 631 Query: 558 PEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPEC-ICTQEHGQGPPRKR 616 S + PE + G + G A A+ E C G PP Sbjct: 632 ---SSSATSTPE-------ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681 Query: 617 KRASEPGDKASKKPSRGRRK------LTATEGPGSPRDAE---DHSPSPNSS 659 + A PG P+ G + TEGP S A D PSP +S Sbjct: 682 RGA--PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTS 731 Score = 52.8 bits (125), Expect = 1e-06 Identities = 90/331 (27%), Positives = 107/331 (32%), Gaps = 57/331 (17%) Query: 369 RAGSVRPRGQ---------PTPGEMLPSLPVGSDSEGPENEGTRAALAAA----GLSGGR 415 RAG R G P G + P + S GP + RA+ G G R Sbjct: 76 RAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135 Query: 416 HTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLS-------PA 468 + R + TEA + D S G G TP PA S + P Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTS--GPTPG--TPSPAMARRSRAAGTEVGLPR 191 Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST----PMDPSRPLPGSQLSLS 524 A +A P PPT+ GP A + T + S SR L S LS Sbjct: 192 PAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250 Query: 525 SPGSTEDEDTGRPLPPPHP-QPPPHP----QPPDLDGHPEPSKAEVLRPESDELDETDTP 579 SP + G P P HP QP P +PP + P A L P S TP Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT-PPRKDAAPALGPLSS--SPLATP 307 Query: 580 GSEVGLSSQAEATTSTTGEGPECIC--------TQEHGQGPPRKRKRASEPGDKASKKPS 631 L SQA T T C PP + S P S+ Sbjct: 308 SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ--- 364 Query: 632 RGRRKLTATEGPGSPRDAEDHS--PSPNSSP 660 AT GSP HS PSP SP Sbjct: 365 -------ATTSLGSPTLQATHSFLPSPPLSP 388 Score = 52.8 bits (125), Expect = 1e-06 Identities = 134/566 (23%), Positives = 174/566 (30%), Gaps = 118/566 (20%) Query: 134 PRAKEGTSDPP----SPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRT 189 P + G PP SP + SPG T P G + + RG+ A R+ Sbjct: 95 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 154 Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACP---------------- 233 + A + P P + R S + + RP A P Sbjct: 155 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 214 Query: 234 ---------ADRGPANG---------------TPPPLPARSSPPSPAYERGLSLDS---- 265 A R P+ G TP PARS P + R + S Sbjct: 215 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKP 274 Query: 266 -FLRASRPSAMT----HEAPKLSPKVDRLCLLNRPLSLHLQS---------PHSS----- 306 L+A RP +T AP L P P S LQS PHSS Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP-SAALQSQAPPTLPATPHSSSLTCQ 333 Query: 307 -----PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQ 361 PLAP + + P LQ L + A + T LG P+ A H L Sbjct: 334 LATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL----------QATHSFLPS 383 Query: 362 QQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGP---ENEGTRAALAAAGLSGGRHTQ 418 L A P P P P S P + ALA L Sbjct: 384 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 443 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG--QDTPKPAGQHGSLSPAAAHTASPE 476 P+ P +A + A+ P + A Q P P SP + +A+P Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA-----SPPMSPSATP- 497 Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL--SSPGSTEDEDT 534 PP PL P L+ + P Q + P + LP S +P S Sbjct: 498 PPQAPPPLAAPPLQLA------KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 551 Query: 535 GRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTS 594 PL P PQ PP P L P P + L+ TPG + +S Sbjct: 552 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR----RPPTPGPDTSVS-------- 599 Query: 595 TTGEGPECICTQEHGQGPPRKRKRAS 620 GP G PP R +S Sbjct: 600 ----GPRLTLALAPGPPPPPSRSPSS 621 Score = 51.6 bits (122), Expect = 2e-06 Identities = 136/572 (23%), Positives = 184/572 (32%), Gaps = 119/572 (20%) Query: 130 DRPKPRAKEGTSDPPSP-LLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHR 188 D+ K A T +P LL P P G + +PP A G KP R Sbjct: 6 DKAKAGAAARTPAARAPGLLTPRPPG----SPRPPPPVTPAALRVLGAAGAVGRKPLAER 61 Query: 189 TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLP- 247 + GAT+PES AP P R + GT S PA R PA+G P Sbjct: 62 AGGIG----GATIPES-APRAGPTRSA----GT-------SSRNPASRPPASGRGERAPP 105 Query: 248 ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSP 307 A+++ P P G + + +RP + + ++S + Sbjct: 106 AKNTSPGPVSSPGRASGT----TRPGPLGQKGLRISAE--------------------ET 141 Query: 308 LAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRAR 367 +A A P+ L A PT G PS +A++ A Sbjct: 142 VARGKATEAPKRSALSAGARRDTSGPTP--GTPSPA---------------MARRSRAAG 184 Query: 368 ARAGSVRPR--GQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRA 425 G RP +P P P V S SE E + AA GG +PA R+ Sbjct: 185 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ-RPAS--RS 241 Query: 426 QRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHG----SLSPAAAHTASPEPPTQS 481 + A A P PKP G ++P A P S Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301 Query: 482 GPL-TRSPQALSNGTKGTRVPEQEEAS-------TPMD---PSRPLPGSQLSLSSPGSTE 530 PL T SP A +P +S TP+ PS P S +L SP +T Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATP 361 Query: 531 DEDTGR--------------------PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPES 570 PL P PQ PP P L P P + L P + Sbjct: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421 Query: 571 DELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKP 630 T +P + L+ + P + PP AS P ++ P Sbjct: 422 -----TPSPQAPNALAVHLLQAPFSPPPSPPV----QAPFSPP-----ASPPVSPSATPP 467 Query: 631 SRGRRKLTA--TEGPGSPRDAEDHSPSPNSSP 660 S+ L A + P SP + SPS P Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 61.6 bits (148), Expect = 2e-09 Identities = 113/473 (23%), Positives = 168/473 (35%), Gaps = 63/473 (13%) Query: 93 SHLQNLQRIFILTNEMN--GLKEENETLKEEV--KRLRVLGDRPKPRAKEGTSDPPSPLL 148 S + L + + N+ N L ++E +EE K+ V ++ KP EG PP Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP---EGIIKPPLQQQ 214 Query: 149 LPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD 208 P P I ++ G + ++D G K + K P T + P Sbjct: 215 PPKP-----IPKQQGPGRDPLQQD-------GTPKSISSQQPEKIKSQPPGTGKPIQGPT 262 Query: 209 MSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP--------SPAYERG 260 +PQ +L RP ++ RG + P LP+ S PP PA + G Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGES--VKPSLPSPSKPPIQQPTPGKPPAQQPG 320 Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320 A P+ + L+ + + +P P + PL PA P+ Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPA----- 373 Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380 + E+P+ P ALA + A QQ A+ V G P Sbjct: 374 -----QQTGSEKPSSEQPGPKALAQPPGVGKTPA------QQPGPAKPPTQQV---GTPK 419 Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440 P P L + + GP T+ + G G Q AGPG+ + T+ + Sbjct: 420 PLAQQPGLQSPAKAPGP----TKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPS-QL 473 Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQS-GPLTRSPQALSNGTKGTR 499 P + G P P Q GS P + S +PP Q GP SPQ + T+ Sbjct: 474 PGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS----TK 528 Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552 P Q+ S +P P + S +G+PL PP P QPP Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPP 580 Score = 48.5 bits (114), Expect = 2e-05 Identities = 69/290 (23%), Positives = 92/290 (31%), Gaps = 66/290 (22%) Query: 371 GSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEA 430 G+ +P QP P+ GS+ E G +A G+ G Q GP + Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP---- 411 Query: 431 AATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490 TQ KPL A Q G SPA A + P Q GP Q Sbjct: 412 --TQQVGTPKPL----------------AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453 Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ 550 G + + P P LPG P PP QP P Sbjct: 454 AGPGKTSA------QQTGPTKPPSQLPG------------------PAKPPPQQPGPAKP 489 Query: 551 PPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610 PP +P A +P S + T P + G A+ + G T+ Q Sbjct: 490 PPQ-----QPGSA---KPPSQQPGSTKPPPQQPG---PAKPSPQQPGS------TKPPSQ 532 Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 P + A +P +K ++ K + G G P SPS P Sbjct: 533 QPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580 Score = 46.6 bits (109), Expect = 7e-05 Identities = 137/650 (21%), Positives = 217/650 (33%), Gaps = 121/650 (18%) Query: 116 ETLKEEVKRLRVLGDRPKPRAKE-----GTSDPPSPLLLPSPGGWKAITEKPPGGHEEAE 170 +T + + +L + D +P+ K+ G S PS LPSP K ++P G A+ Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS---LPSPS--KPPIQQPTPGKPPAQ 317 Query: 171 EDHQGVGLRGEEKPAGHR---TSPVAKIS---------PGATLPESR--------APDMS 210 + G KP T P+A+ PG T P ++ A Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377 Query: 211 PQRISNQLHGTIAVVRP-GSQACPADR-GPAN------GTPPPLPARSSPPSPAYERGLS 262 ++ S++ G A+ +P G PA + GPA GTP PL + SPA G + Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437 Query: 263 LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLH--LQSPHSSPLAPAAAPSDPRLQ 320 + +A + P L + P P P P Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497 Query: 321 DLKAREAEAWEEPTELLG----LPSALAGMQDLRLEGALHLLLAQQQLRARARAG-SVRP 375 +++ + + P + G P + + AQQ A+ A S +P Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 376 RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQD 435 Q G+ L V ++ P ++G + L P +A Q Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP--LCNTTELLLHVPEKANFNTCTECQT 615 Query: 436 -----CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTR---- 486 C + L+E + G L+P + SP+P ++ P+T Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS---SPQPKLKTAPVTTTSAV 672 Query: 487 ---SPQALSNGTKGTRVPEQEEASTPMDPSRPLP--------GSQLSLSSPGSTEDEDTG 535 SPQ K P+Q+ + P +P +P P GS S + E + Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAP-EPKKPPPLVKQPTLHGSP-SAKAKQPPEADSLS 730 Query: 536 RPLPPPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDET------DTPGSEVGLSSQ 588 +P PP P P + P D P+ K +++P +D + + D P S+V SQ Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKV--QSQ 786 Query: 589 AEATTST---------------TGE-----------------------GPECICTQEHGQ 610 AE T+ TGE GP + Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846 Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 P +K++ + K S KP + PG A P+P SP Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896 Score = 43.5 bits (101), Expect = 6e-04 Identities = 54/215 (25%), Positives = 77/215 (35%), Gaps = 30/215 (13%) Query: 452 GQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPL---TRSPQALSNGTKGTRVPEQEEAST 508 G+D + G S+S +PP P+ T++PQ T ++P Q +AS Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ-----TDHAKLPLQRDASR 280 Query: 509 PMDPSRPLP-GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH----PEPSKA 563 P + G + S P P PP QP P P GH P P+K Sbjct: 281 PQTKQADIVRGESVKPSLPS---------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331 Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTSTTGE--GPECICTQEHGQGPPRKRKRASE 621 +P PG+ V Q TT + GP Q+ G P + + Sbjct: 332 PA-QPSGLTKPLAQQPGT-VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP----SSEQ 385 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656 PG KA +P + GP P + +P P Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Score = 42.0 bits (97), Expect = 0.002 Identities = 84/408 (20%), Positives = 135/408 (33%), Gaps = 42/408 (10%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-LHGTIAVVRPGSQACPADRGPA 239 + P +TSP +P L ++ P P + LHG+ + + PA Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 240 NGTPPPLPARS-----SPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 P +P+ + P + + + L +S + + P + Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793 Query: 295 PLSLHLQSPHSS--PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLR-L 351 PL P S P +P D + A +++ P G S G + + + Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSSESKGQKQVDPV 849 Query: 352 EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPS----LPVGSDSEGPENEGTRAALA 407 + AQ ++ + A + P+G PTP P+ +P S P+ + R +L Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908 Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSP 467 ++ +QP P Q T S GQ P P Q G +P Sbjct: 909 LGSITDAPKSQPTTP---QETVTGKLFGFGASIFSQASNLISTAGQ--PGPHSQSGPGAP 963 Query: 468 AAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG 527 A +PPT GP + QA K +P ++E P Q Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKS--IPVKKETKAPAAEKLEPKAEQAPTVKRT 1021 Query: 528 STEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE----PSKAEVL-RPES 570 TE +PPP L P+ P+K E +PES Sbjct: 1022 ETE------------KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057 Score = 41.2 bits (95), Expect = 0.003 Identities = 119/569 (20%), Positives = 199/569 (34%), Gaps = 86/569 (15%) Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEK 161 ++E G K+ + K+E + PKP AK +G+ PP P P+ G ++ Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR--PTAGQTVPTPQQ 894 Query: 162 PPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISP-----GATLPESRAPDMS----PQ 212 P E++ +G + P T+P ++ GA++ + +S P Sbjct: 895 SPKPQEQSRRFSLNLGSI-TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953 Query: 213 RISNQLHGTIAVVRPGSQACPADRGP--ANGTPPPLPARSSP-----PSPAYERGLSLDS 265 S G P P +GP + G PP PA+S P +PA E+ L+ Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK---LEP 1010 Query: 266 FLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKA 324 + T K P D L P L + SP + P ++ + Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070 Query: 325 REAEAWEEPTELLGLPSALAGMQDLRLEGALH---LLLAQQQLRARARAGSVRPRGQPTP 381 ++ + TE L G + L Q Q + G +R Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130 Query: 382 GEMLPSLPVGSDSEGPEN-------------------------EGTRAALAAAGLSGGRH 416 G +PV ++S + E + L+ + Sbjct: 1131 GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190 Query: 417 T-QPAGPGRAQRTEAAATQDCALDKPLD-----LSEWGRARGQDTP------KPAGQHGS 464 T Q + ++ +A+A Q+ KPL + E + R ++ KP + Sbjct: 1191 TDQKQEESKLEKDKASALQE---KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247 Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ--EEASTPMDPSRPLP-GSQL 521 L P A +A P Q L +S ++ RV + +E P LP G+ Sbjct: 1248 LLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQ 1304 Query: 522 SLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGS 581 SL ED+ T + + PQPP +P ++ E ++ E + + + P S Sbjct: 1305 SLPK----EDDKTTKTIKE-QPQPPCTAKPDQVEPGKEKTEKE---DDKSDTSSSQQPKS 1356 Query: 582 EVGLSS---QAEATTSTTGEGPECICTQE 607 GLS ++ +S+ GE P I T E Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385 Score = 35.0 bits (79), Expect = 0.22 Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 25/140 (17%) Query: 500 VPEQEEASTPMDPS-----RPLPGSQLSLSSPG-------------STEDEDTGRPLPPP 541 +P +E+ ST S + P SQL SP S+ + + +P PPP Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409 Query: 542 HPQPPPHPQPPDLDGHPEP---SKAEVLRPESD----ELDETDTPGSEVGLSSQAEATTS 594 P PPP P PP P P S + P+ T TP + + + A Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469 Query: 595 TTGEGPECICTQEHGQGPPR 614 + G ICT PP+ Sbjct: 2470 SNGLPVTRICTTAPPPVPPK 2489 Score = 29.6 bits (65), Expect = 9.3 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Query: 190 SPVAKISPGATLPESRAP-------DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGT 242 SP++ +SPG L + P D+SPQ++ LH +A V P S + Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKV---LHPDMAKVPPASPKTAKMMQRSMSD 3681 Query: 243 PPPLPARSSPPSPA 256 P PL + S A Sbjct: 3682 PKPLSPTADESSRA 3695 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 61.6 bits (148), Expect = 2e-09 Identities = 113/473 (23%), Positives = 168/473 (35%), Gaps = 63/473 (13%) Query: 93 SHLQNLQRIFILTNEMN--GLKEENETLKEEV--KRLRVLGDRPKPRAKEGTSDPPSPLL 148 S + L + + N+ N L ++E +EE K+ V ++ KP EG PP Sbjct: 158 SEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKP---EGIIKPPLQQQ 214 Query: 149 LPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPD 208 P P I ++ G + ++D G K + K P T + P Sbjct: 215 PPKP-----IPKQQGPGRDPLQQD-------GTPKSISSQQPEKIKSQPPGTGKPIQGPT 262 Query: 209 MSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP--------SPAYERG 260 +PQ +L RP ++ RG + P LP+ S PP PA + G Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGES--VKPSLPSPSKPPIQQPTPGKPPAQQPG 320 Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320 A P+ + L+ + + +P P + PL PA P+ Sbjct: 321 HEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPA----- 373 Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380 + E+P+ P ALA + A QQ A+ V G P Sbjct: 374 -----QQTGSEKPSSEQPGPKALAQPPGVGKTPA------QQPGPAKPPTQQV---GTPK 419 Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK 440 P P L + + GP T+ + G G Q AGPG+ + T+ + Sbjct: 420 PLAQQPGLQSPAKAPGP----TKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPS-QL 473 Query: 441 PLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQS-GPLTRSPQALSNGTKGTR 499 P + G P P Q GS P + S +PP Q GP SPQ + T+ Sbjct: 474 PGPAKPPPQQPGPAKPPPQ-QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS----TK 528 Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552 P Q+ S +P P + S +G+PL PP P QPP Sbjct: 529 PPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSA-KQPP 580 Score = 48.5 bits (114), Expect = 2e-05 Identities = 69/290 (23%), Positives = 92/290 (31%), Gaps = 66/290 (22%) Query: 371 GSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEA 430 G+ +P QP P+ GS+ E G +A G+ G Q GP + Sbjct: 357 GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGV-GKTPAQQPGPAKPP---- 411 Query: 431 AATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQA 490 TQ KPL A Q G SPA A + P Q GP Q Sbjct: 412 --TQQVGTPKPL----------------AQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQ 453 Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ 550 G + + P P LPG P PP QP P Sbjct: 454 AGPGKTSA------QQTGPTKPPSQLPG------------------PAKPPPQQPGPAKP 489 Query: 551 PPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610 PP +P A +P S + T P + G A+ + G T+ Q Sbjct: 490 PPQ-----QPGSA---KPPSQQPGSTKPPPQQPG---PAKPSPQQPGS------TKPPSQ 532 Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 P + A +P +K ++ K + G G P SPS P Sbjct: 533 QPGSAKPSAQQP--SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580 Score = 46.6 bits (109), Expect = 7e-05 Identities = 137/650 (21%), Positives = 217/650 (33%), Gaps = 121/650 (18%) Query: 116 ETLKEEVKRLRVLGDRPKPRAKE-----GTSDPPSPLLLPSPGGWKAITEKPPGGHEEAE 170 +T + + +L + D +P+ K+ G S PS LPSP K ++P G A+ Sbjct: 263 QTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPS---LPSPS--KPPIQQPTPGKPPAQ 317 Query: 171 EDHQGVGLRGEEKPAGHR---TSPVAKIS---------PGATLPESR--------APDMS 210 + G KP T P+A+ PG T P ++ A Sbjct: 318 QPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTG 377 Query: 211 PQRISNQLHGTIAVVRP-GSQACPADR-GPAN------GTPPPLPARSSPPSPAYERGLS 262 ++ S++ G A+ +P G PA + GPA GTP PL + SPA G + Sbjct: 378 SEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPT 437 Query: 263 LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLH--LQSPHSSPLAPAAAPSDPRLQ 320 + +A + P L + P P P P Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497 Query: 321 DLKAREAEAWEEPTELLG----LPSALAGMQDLRLEGALHLLLAQQQLRARARAG-SVRP 375 +++ + + P + G P + + AQQ A+ A S +P Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 376 RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQD 435 Q G+ L V ++ P ++G + L P +A Q Sbjct: 558 VSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICP--LCNTTELLLHVPEKANFNTCTECQT 615 Query: 436 -----CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTR---- 486 C + L+E + G L+P + SP+P ++ P+T Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS---SPQPKLKTAPVTTTSAV 672 Query: 487 ---SPQALSNGTKGTRVPEQEEASTPMDPSRPLP--------GSQLSLSSPGSTEDEDTG 535 SPQ K P+Q+ + P +P +P P GS S + E + Sbjct: 673 SKSSPQPQQTSPKKDAAPKQDLSKAP-EPKKPPPLVKQPTLHGSP-SAKAKQPPEADSLS 730 Query: 536 RPLPPPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDET------DTPGSEVGLSSQ 588 +P PP P P + P D P+ K +++P +D + + D P S+V SQ Sbjct: 731 KPAPPKEPSVPSEQDKAPVADDKPKQPK--MVKPTTDLVSSSSATTKPDIPSSKV--QSQ 786 Query: 589 AEATTST---------------TGE-----------------------GPECICTQEHGQ 610 AE T+ TGE GP + Sbjct: 787 AEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQV 846 Query: 611 GPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSP 660 P +K++ + K S KP + PG A P+P SP Sbjct: 847 DPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896 Score = 43.5 bits (101), Expect = 6e-04 Identities = 54/215 (25%), Positives = 77/215 (35%), Gaps = 30/215 (13%) Query: 452 GQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPL---TRSPQALSNGTKGTRVPEQEEAST 508 G+D + G S+S +PP P+ T++PQ T ++P Q +AS Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ-----TDHAKLPLQRDASR 280 Query: 509 PMDPSRPLP-GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGH----PEPSKA 563 P + G + S P P PP QP P P GH P P+K Sbjct: 281 PQTKQADIVRGESVKPSLPS---------PSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP 331 Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTSTTGE--GPECICTQEHGQGPPRKRKRASE 621 +P PG+ V Q TT + GP Q+ G P + + Sbjct: 332 PA-QPSGLTKPLAQQPGT-VKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP----SSEQ 385 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656 PG KA +P + GP P + +P P Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKP 420 Score = 42.0 bits (97), Expect = 0.002 Identities = 84/408 (20%), Positives = 135/408 (33%), Gaps = 42/408 (10%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-LHGTIAVVRPGSQACPADRGPA 239 + P +TSP +P L ++ P P + LHG+ + + PA Sbjct: 674 KSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPA 733 Query: 240 NGTPPPLPARS-----SPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 P +P+ + P + + + L +S + + P + Sbjct: 734 PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTP 793 Query: 295 PLSLHLQSPHSS--PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLR-L 351 PL P S P +P D + A +++ P G S G + + + Sbjct: 794 PLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSSESKGQKQVDPV 849 Query: 352 EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPS----LPVGSDSEGPENEGTRAALA 407 + AQ ++ + A + P+G PTP P+ +P S P+ + R +L Sbjct: 850 QKKEEPKKAQTKMSPKPDAKPM-PKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLN 908 Query: 408 AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSP 467 ++ +QP P Q T S GQ P P Q G +P Sbjct: 909 LGSITDAPKSQPTTP---QETVTGKLFGFGASIFSQASNLISTAGQ--PGPHSQSGPGAP 963 Query: 468 AAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG 527 A +PPT GP + QA K +P ++E P Q Sbjct: 964 MKQAPAPSQPPTSQGPPKSTGQAPPAPAKS--IPVKKETKAPAAEKLEPKAEQAPTVKRT 1021 Query: 528 STEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE----PSKAEVL-RPES 570 TE +PPP L P+ P+K E +PES Sbjct: 1022 ETE------------KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPES 1057 Score = 41.2 bits (95), Expect = 0.003 Identities = 119/569 (20%), Positives = 199/569 (34%), Gaps = 86/569 (15%) Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEK 161 ++E G K+ + K+E + PKP AK +G+ PP P P+ G ++ Sbjct: 837 SSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPR--PTAGQTVPTPQQ 894 Query: 162 PPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISP-----GATLPESRAPDMS----PQ 212 P E++ +G + P T+P ++ GA++ + +S P Sbjct: 895 SPKPQEQSRRFSLNLGSI-TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953 Query: 213 RISNQLHGTIAVVRPGSQACPADRGP--ANGTPPPLPARSSP-----PSPAYERGLSLDS 265 S G P P +GP + G PP PA+S P +PA E+ L+ Sbjct: 954 PHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEK---LEP 1010 Query: 266 FLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKA 324 + T K P D L P L + SP + P ++ + Sbjct: 1011 KAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGS 1070 Query: 325 REAEAWEEPTELLGLPSALAGMQDLRLEGALH---LLLAQQQLRARARAGSVRPRGQPTP 381 ++ + TE L G + L Q Q + G +R Sbjct: 1071 KDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQLGDIRKMPPAPS 1130 Query: 382 GEMLPSLPVGSDSEGPEN-------------------------EGTRAALAAAGLSGGRH 416 G +PV ++S + E + L+ + Sbjct: 1131 GPKASPMPVPTESSSQKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190 Query: 417 T-QPAGPGRAQRTEAAATQDCALDKPLD-----LSEWGRARGQDTP------KPAGQHGS 464 T Q + ++ +A+A Q+ KPL + E + R ++ KP + Sbjct: 1191 TDQKQEESKLEKDKASALQE---KKPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKK 1247 Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ--EEASTPMDPSRPLP-GSQL 521 L P A +A P Q L +S ++ RV + +E P LP G+ Sbjct: 1248 LLPEAKTSA---PEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQ 1304 Query: 522 SLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGS 581 SL ED+ T + + PQPP +P ++ E ++ E + + + P S Sbjct: 1305 SLPK----EDDKTTKTIKE-QPQPPCTAKPDQVEPGKEKTEKE---DDKSDTSSSQQPKS 1356 Query: 582 EVGLSS---QAEATTSTTGEGPECICTQE 607 GLS ++ +S+ GE P I T E Sbjct: 1357 PQGLSDTGYSSDGISSSLGEIPSLIPTDE 1385 Score = 35.0 bits (79), Expect = 0.22 Identities = 37/140 (26%), Positives = 52/140 (37%), Gaps = 25/140 (17%) Query: 500 VPEQEEASTPMDPS-----RPLPGSQLSLSSPG-------------STEDEDTGRPLPPP 541 +P +E+ ST S + P SQL SP S+ + + +P PPP Sbjct: 2350 LPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPP 2409 Query: 542 HPQPPPHPQPPDLDGHPEP---SKAEVLRPESD----ELDETDTPGSEVGLSSQAEATTS 594 P PPP P PP P P S + P+ T TP + + + A Sbjct: 2410 PPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLR 2469 Query: 595 TTGEGPECICTQEHGQGPPR 614 + G ICT PP+ Sbjct: 2470 SNGLPVTRICTTAPPPVPPK 2489 Score = 29.6 bits (65), Expect = 9.3 Identities = 22/74 (29%), Positives = 32/74 (43%), Gaps = 10/74 (13%) Query: 190 SPVAKISPGATLPESRAP-------DMSPQRISNQLHGTIAVVRPGSQACPADRGPANGT 242 SP++ +SPG L + P D+SPQ++ LH +A V P S + Sbjct: 3625 SPISPLSPGKALESAFVPYEKPLPDDISPQKV---LHPDMAKVPPASPKTAKMMQRSMSD 3681 Query: 243 PPPLPARSSPPSPA 256 P PL + S A Sbjct: 3682 PKPLSPTADESSRA 3695 >gi|116256464 hypothetical protein LOC343990 [Homo sapiens] Length = 962 Score = 61.6 bits (148), Expect = 2e-09 Identities = 137/558 (24%), Positives = 189/558 (33%), Gaps = 107/558 (19%) Query: 142 DPPSPLL---LPSPGGWKAITEKPPGGH-EEAEEDHQGVGLRGEEK--------PAGHRT 189 +PPSP P P G K E PP G A + + V E+ P G T Sbjct: 353 EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTT 412 Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249 P + P AT A D + + + T V+ ++GP P P P R Sbjct: 413 PP--ETDPAATSEAPSARDGPERSVPKEAEPTPPVLPD------EEKGPPG--PAPEPER 462 Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLA 309 + P ERG + + PS AP SP + CL +RP + S PLA Sbjct: 463 EAETEP--ERGAGTEPERIGTEPST----APAPSPPAPKSCLKHRPAAASEGPAASPPLA 516 Query: 310 PAAAPS-DPRLQDL----------KAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358 A +P +P L KA AEA E P A L GA Sbjct: 517 AAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAE-RAAPERKAERGGAELRGAKKFS 575 Query: 359 LAQQQLRARARAGSVRP--------------------------RGQPTPGEMLPSLPVGS 392 ++ RAR R G RP +G P P P P Sbjct: 576 VS--SCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPG-PRKL 632 Query: 393 DSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK---PLDLS---- 445 GP++ G RAA + AG A PG + AA + D+ P+ L Sbjct: 633 AERGPQDSGDRAA-SPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691 Query: 446 --EWGRARGQDTPKPAGQHGSLSPAAAHTASPEP---PTQSGPLTRSPQALSNGTKGTRV 500 ++ Q+ + + T P+ P + P R +A S+ KG Sbjct: 692 SLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKAR 751 Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEP 560 P + +S P P +PL S PH PP P + + EP Sbjct: 752 PPEPLSSKPPLPRKPLLQS------------------FTLPHQPAPPDAGPGEREPRKEP 793 Query: 561 SKAEVLRPESDELDETDTPGSEVGLSSQAEAT----TSTTGEGPECICTQEHGQGPPRKR 616 AE RP E P + G + + T T + + + + P R Sbjct: 794 RTAE-KRPLRRGA-EKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGAR 851 Query: 617 KRASEPGDKASKKPSRGR 634 SEPG K +K P RG+ Sbjct: 852 TLKSEPG-KQAKVPERGQ 868 Score = 55.8 bits (133), Expect = 1e-07 Identities = 114/456 (25%), Positives = 154/456 (33%), Gaps = 45/456 (9%) Query: 183 KPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVV---RP--GSQACPADRG 237 KP R+S + ++S A +P+ N+ + V RP G Q DRG Sbjct: 231 KPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRG 290 Query: 238 PANGTPPPLPARSSPPSPAYERGLSL--DSFLRAS-RPSAMTHEAPKLSPKVDRLCLLNR 294 P G P PLP PP A R L S L AS + E P P L Sbjct: 291 PEPGPPAPLP----PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES 346 Query: 295 PLSLHLQSPHSSPLAPAAAPSDPRLQDLKARE----AEAWEEPTELLGLPSALAGMQDLR 350 +L ++ P S P P D QD +A A A ++ E++ P +A Sbjct: 347 APTLRVEPP-SPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTA 405 Query: 351 L-EGALHLLLAQQQLRARARAGSVRPRGQ-PTPGEMLPSLPVGSDSE----GPENEGTRA 404 + EG + A + A S R + P E P+ PV D E GP E R Sbjct: 406 IPEG--DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPERE 463 Query: 405 ALAAAGLSGGRHTQPAG--PGRAQRTEAAATQDCALDKPLDLSEWGRA----RGQDTPKP 458 A G + G P A A + C +P SE A ++P Sbjct: 464 AETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPV 523 Query: 459 AGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTK---GTRVPEQEEASTPMDPSRP 515 GSL AA P+ P + +A G + ++ S +RP Sbjct: 524 EPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP 583 Query: 516 LPGSQLSLSSPGSTEDEDTGR-PLPPPHPQPPPHPQPPDLDGHPEPSKAEV---LRPESD 571 PG L + +GR PL P DL G PEP A+ E Sbjct: 584 RPGVSRPL-------ERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERG 636 Query: 572 ELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQE 607 D D S G + + G C QE Sbjct: 637 PQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQE 672 Score = 39.3 bits (90), Expect = 0.012 Identities = 56/224 (25%), Positives = 81/224 (36%), Gaps = 53/224 (23%) Query: 474 SPEPPTQSGPLTRS----PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGST 529 +P PP R+ AL+ + VP ++ +S P P P Sbjct: 297 APLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP------------ 344 Query: 530 EDEDTGRPLPPPHPQPPPHPQPP--DLDGHPEPS--------KAE--------VLRPESD 571 E T R PP P+ PP+P P DG P+ KAE V P Sbjct: 345 ESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPT 404 Query: 572 ELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQE---------------HGQGPPRKR 616 + E DT E ++ +EA ++ +GPE +E G P +R Sbjct: 405 AIPEGDTTPPETDPAATSEAPSAR--DGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER 462 Query: 617 KRASEPGDKASKKPSR-GRRKLTA-TEGPGSPRDAEDHSPSPNS 658 + +EP A +P R G TA P +P+ H P+ S Sbjct: 463 EAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAAS 506 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 59.3 bits (142), Expect = 1e-08 Identities = 100/517 (19%), Positives = 183/517 (35%), Gaps = 58/517 (11%) Query: 180 GEEKPAGHRTSPVAKIS---------PGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQ 230 G +P G +P++ + PG +P+ + + +++ + + G+ Sbjct: 2134 GMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTA 2193 Query: 231 ACPADRGPA------NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS- 283 P A + P P+P S +PA +L S + A+ +AM + + Sbjct: 2194 RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPA----ANLASRIPAASAAAMNLASARTPA 2249 Query: 284 -PKVDRLCLLNRPLS---LHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGL 339 P L P + ++L SP ++ A +DPR A P L L Sbjct: 2250 IPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAAL 2309 Query: 340 PSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPEN 399 +G A + + + +A A A V PR + ++ + Sbjct: 2310 SLTGSGTPPT----AANYPSSSRTPQAPASANLVGPRSAHATAPV--NIAGSRTAAALAP 2363 Query: 400 EGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDK-----PLDLSEWGRARGQD 454 +A A LSG T P P A + T LD+ P R + Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423 Query: 455 TPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514 P P+ + G A + S PP Q P + P A S+ ++ +TP+ S+ Sbjct: 2424 APSPSSRMGQ-----APSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQ-----TTPVAGSQ 2473 Query: 515 PLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELD 574 L ++ ++ S D + +P P +PP G +PS L+P + Sbjct: 2474 SLSSGAVATTT-SSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRS 2532 Query: 575 ETDTPGSEVGLSSQAEATTSTTGEGPECICTQ------------EHGQGPPRKRKRASEP 622 + + S SS + +++S++ G ++ + P K A Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592 Query: 623 GDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 G P++ +R+ +++ S + S S +SS Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSS 2629 Score = 57.8 bits (138), Expect = 3e-08 Identities = 125/555 (22%), Positives = 191/555 (34%), Gaps = 73/555 (13%) Query: 172 DHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAP-DMSPQRISNQLHGTIAVV----- 225 DHQ + P H S +A +L +R P MS ++ ++ A V Sbjct: 2166 DHQRTSV-----PENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSL 2220 Query: 226 RPGSQACPADRGPA---------NGTPPPLPAR---SSPPSPAYERGLSLDSFLRASRPS 273 R A A R PA + P +P + +PA ++L S A PS Sbjct: 2221 RTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPS 2280 Query: 274 AMTHEAPKL--SPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA--------PSDPRLQDLK 323 A+ P+ +P V+ L P +L S S P AA P P +L Sbjct: 2281 AVNLADPRTPTAPAVN-LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLV 2339 Query: 324 AREAEAWEEPTELLGLPSALA----GMQDLRLEGAL---HLLLAQQQLRARAR-AGSVRP 375 + P + G +A A + R+ AL +L + L A R +G P Sbjct: 2340 GPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSP 2399 Query: 376 ----RGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP---GRAQRT 428 R + PS + P + L QP P + ++ Sbjct: 2400 PLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQS 2459 Query: 429 EAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSL----SPAAAHTASPEPPTQSGPL 484 Q + LS A T AG H + +P H+ EPP +G Sbjct: 2460 RCLIAQTTPVAGSQSLSSGAVAT---TTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQ 2516 Query: 485 TRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH-- 542 S A K R +S+ S S S S S++ E + P+ P Sbjct: 2517 QPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVAL 2576 Query: 543 ---PQPPPHPQPPDLDGHP-EPSKAE-VLRPESDELDETDTPGSEVGLSSQAEATTSTTG 597 P P P P+ +G P EP+ A+ R S + + S SS + +++S++ Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636 Query: 598 EGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP-GSPRDA------- 649 + P + +A P + KKP G R+ + P S RD+ Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQAL-PKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSP 2695 Query: 650 -EDHSPSPNSSPWEE 663 E PSP SP ++ Sbjct: 2696 VERRRPSPQPSPRDQ 2710 Score = 43.1 bits (100), Expect = 8e-04 Identities = 111/523 (21%), Positives = 171/523 (32%), Gaps = 74/523 (14%) Query: 131 RPKPRAKEGTSDP----PSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAG 186 RP P + ++ P P+PLL GG P E + R P Sbjct: 349 RPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408 Query: 187 HRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPL 246 P + S ES P P ++S A P + P P Sbjct: 409 PEKLPQSSSS------ESSPPSPQPTKVSRH----------------ASSSPESPKPAPA 446 Query: 247 PAR-----SSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQ 301 P SSP S G RA R + +H + + R S + Sbjct: 447 PGSHREISSSPTSKNRSHG-------RAKRDKSHSHTPSRRMGRSRSPATAKRGRS-RSR 498 Query: 302 SPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQ 361 +P + + +P Q ++R A+ W P + + G Q Sbjct: 499 TPTKRGHSRSRSP-----QWRRSRSAQRWGRSRS----PQRRGRSRSPQRPGWSRSRNTQ 549 Query: 362 QQLRAR-ARAGSVRPRGQPTPGEMLPSLPVG---SDSEGPENEGTRAALAAAGLSGGRHT 417 ++ R+R AR G R T G P S S P +R+ S R Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSR-- 607 Query: 418 QPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEP 477 PA GR+ R+ A + P+ R+R + + +G+ S +PA + Sbjct: 608 TPARRGRS-RSRTPARRRSRTRSPVRR----RSRSRSPARRSGRSRSRTPARRGRSRSRT 662 Query: 478 PTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR- 536 P + G A +G +R P + S P R S+ SL G + R Sbjct: 663 PARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSR-SLVRRGRSHSRTPQRR 721 Query: 537 ----PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEAT 592 + + + PE K+ + S L +P S+ S+ Sbjct: 722 GRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSL---SSPRSKA--KSRLSLR 776 Query: 593 TSTTGEGPECICTQEHGQGPPRK-RKRASEPGDKASKKPSRGR 634 S +G P C ++ Q PPR+ R +S+P K+ P R R Sbjct: 777 RSLSGSSP---CPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSR 816 Score = 38.1 bits (87), Expect = 0.026 Identities = 120/589 (20%), Positives = 180/589 (30%), Gaps = 88/589 (14%) Query: 131 RPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPG-----GHEEAEEDHQ----------- 174 +P ++ +S P SP P+PG + I+ P G + ++ H Sbjct: 426 QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485 Query: 175 --GVGLRGEEKPA-----GH--------RTSPVAKISPGATLPESRAPDMSPQRI----- 214 RG + GH R S A+ + P+ R SPQR Sbjct: 486 SPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRS 545 Query: 215 -SNQLHGTIAVVRPGSQ--ACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASR 271 + Q G R G PA RG + P RS +PA R S R SR Sbjct: 546 RNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605 Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWE 331 S R R S + S + ++R Sbjct: 606 SRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPAR 665 Query: 332 EPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVG 391 P+ +G R ++ R R+R+ S+ RG+ G Sbjct: 666 RGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSG 725 Query: 392 SDSE----------------GPENEGTR-AALAAAGLSGGRH--------------TQPA 420 S SE PE + +R ++ + LS R + P Sbjct: 726 SSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPC 785 Query: 421 GPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQ 480 ++Q + + K + R+R +P P + + S + ++SP P + Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVK 845 Query: 481 SGPLTR-----SPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535 SG R SPQA R E + P SR S SSP + Sbjct: 846 SGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPP 905 Query: 536 RPLPPPHPQPPP------HPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLS--- 586 R P P P P+ G PS + V + + +P S V Sbjct: 906 RQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLP 965 Query: 587 --SQAEATTSTTGEGPECICTQEHGQ--GPPRKRKRASEPGDKASKKPS 631 S + +++ T PE Q H P K K + PG S S Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKS 1014 Score = 37.7 bits (86), Expect = 0.034 Identities = 54/268 (20%), Positives = 89/268 (33%), Gaps = 22/268 (8%) Query: 391 GSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRA--QRTEAAATQDCALDKPLDLSEWG 448 GS+S + R L SG P + +R+E+ ++ D L + Sbjct: 1518 GSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQ-- 1575 Query: 449 RARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508 R+R +P+ LSP + + S S + P+A G+ + +A Sbjct: 1576 RSRSGSSPE-VDSKSRLSPRRSRSGS------SPEVKDKPRAAPRAQSGSDSSPEPKAPA 1628 Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRP 568 P R LP S SS G P+ PP + P R Sbjct: 1629 P----RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRT 1684 Query: 569 ESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASK 628 +P E+ ++ + + PE + PPR R+ S + ++ Sbjct: 1685 PPRRRSSRSSP--ELTRKARLSRRSRSASSSPET-----RSRTPPRHRRSPSVSSPEPAE 1737 Query: 629 KPSRGRRKLTATEGPGSPRDAEDHSPSP 656 K RR+ +A+ SPSP Sbjct: 1738 KSRSSRRRRSASSPRTKTTSRRGRSPSP 1765 Score = 37.7 bits (86), Expect = 0.034 Identities = 103/514 (20%), Positives = 166/514 (32%), Gaps = 92/514 (17%) Query: 139 GTSDPPSPLLLPSPGGW-----KAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193 G+ PP+ PS A P H A + G PA ++ +A Sbjct: 2313 GSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMA 2372 Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP 253 GA L R P + +R+S + T PPL R+ Sbjct: 2373 PALSGANLTSPRVPLSAYERVSGR------------------------TSPPLLDRARSR 2408 Query: 254 SPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA 313 +P S + RA PS+ +AP S L P +SP P+A Sbjct: 2409 TPPSAPSQSRMTSERAPSPSSRMGQAPSQS--------LLPPAQDQPRSP-----VPSAF 2455 Query: 314 PSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSV 373 R L+ + +AG Q L GA+ A A G + Sbjct: 2456 SDQSRC----------------LIAQTTPVAGSQSLS-SGAV----ATTTSSAGDHNGML 2494 Query: 374 RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433 P PG +P VG E P + G + A A L + + + + + ++++ Sbjct: 2495 ---SVPAPG--VPHSDVG---EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSS 2546 Query: 434 QDCALDKPLDLSEWGRARGQDTPKPAG----QHGSLSPAAAHTASPEPPTQSGPLTRSPQ 489 + S + G P + S +PA P + P R + Sbjct: 2547 SSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRR 2606 Query: 490 ALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP 549 + S+ + + +S+ S S S SS S+ +P P P+P Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666 Query: 550 QPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHG 609 +PP P ++ R D L ++ + S E + P ++ Sbjct: 2667 KPP-----PGERRSRSPRKPIDSLRDSRSLS-----YSPVERRRPSPQPSP-----RDQQ 2711 Query: 610 QGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643 + R + GD S+ PS RR+ T + P Sbjct: 2712 SSSSERGSRRGQRGD--SRSPSHKRRRETPSPRP 2743 Score = 35.8 bits (81), Expect = 0.13 Identities = 56/259 (21%), Positives = 88/259 (33%), Gaps = 16/259 (6%) Query: 417 TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE 476 T P+ + Q T ++ L P + + G + Q P +P+ ++S Sbjct: 1365 TDPSLDMKEQSTRSSGHSSSELS-PDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSAS 1423 Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536 P L R+P S + + + S PG + +P E Sbjct: 1424 SPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS 1483 Query: 537 PLPPPHPQPPP----HPQPPDLDGHPEPSKAEVLRPES--DELDETDTP-------GSEV 583 P P PQ P P P+L+ + E ES D+ TP GS Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA--SEPGDKASKKPSRGRRKLTATE 641 L + A+ E ++ + P R+R R+ S D S+ R R ++ E Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPE 1603 Query: 642 GPGSPRDAEDHSPSPNSSP 660 PR A +SSP Sbjct: 1604 VKDKPRAAPRAQSGSDSSP 1622 Score = 32.7 bits (73), Expect = 1.1 Identities = 74/322 (22%), Positives = 111/322 (34%), Gaps = 60/322 (18%) Query: 365 RARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGR 424 R+R+R+ + + G PS G EG A + G + + +P+ P Sbjct: 276 RSRSRSAAAKTHTTALAGRS-PSPASGRRGEGD------APFSEPGTTSTQ--RPSSPET 326 Query: 425 AQRTEAAATQDCALDKPL----------DLSEWGRARGQDTPKPAGQHG-SLSPAAAHTA 473 A + ++ +D DK + S G TP A +HG S P A Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386 Query: 474 SPEP--------PTQSGPLTRSPQALSNGTKGTRVPEQEE--------ASTPMDPS-RPL 516 S EP PT+ +SP+ L + P + +S+P P P Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446 Query: 517 PGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDET 576 PGS +SS ++++ GR + H P S A R S T Sbjct: 447 PGSHREISSSPTSKNRSHGRA-----KRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPT 501 Query: 577 DTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQG-PPRKRKRASEPGDKASKKPSRGRR 635 G S Q + S Q G+ P++R R+ P ++P R Sbjct: 502 KR-GHSRSRSPQWRRSRS----------AQRWGRSRSPQRRGRSRSP-----QRPGWSRS 545 Query: 636 KLTATEGPG-SPRDAEDHSPSP 656 + T G S R HS SP Sbjct: 546 RNTQRRGRSRSARRGRSHSRSP 567 Score = 32.0 bits (71), Expect = 1.9 Identities = 120/641 (18%), Positives = 209/641 (32%), Gaps = 119/641 (18%) Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVL-GDRPKPRAKEGTS 141 +R Q+ S+ +++ I + L K + R L G P P+ K T Sbjct: 734 SRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTP 793 Query: 142 DPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGA-- 199 S P KA + PP + + + + +SP K+ G Sbjct: 794 PRRSRSGSSQP---KAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPP 850 Query: 200 -----TLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254 T P++ ++PQR S P ++ R +G+ PP S+PP Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSP----DPELKSRTPSRHSCSGSSPPRVKSSTPPR 906 Query: 255 PAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP----------- 303 + R S ++A + SP R+ P SP Sbjct: 907 QSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPR 966 Query: 304 ----------------------HSSPLAP-----AAAPSDPRLQDLKAREAEAWEEPTEL 336 HS ++P A P P L K+ + + + + Sbjct: 967 YSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLV 1026 Query: 337 LGLPSAL---AGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSD 393 P +L AG++ G + ++ QL+ ++ Q +P SD Sbjct: 1027 QSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQS---------QTSPDHR-------SD 1070 Query: 394 SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQ 453 + PE + + + L T P G GR++ ++ + A P+ + RG+ Sbjct: 1071 TSSPEVRQSHS--ESPSLQSKSQTSPKG-GRSR--SSSPVTELASRSPI-----RQDRGE 1120 Query: 454 DTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPS 513 + P + G +SP + S + S P S L T +++ A P + + Sbjct: 1121 FSASPMLKSG-MSPEQSRFQS---DSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDA 1176 Query: 514 RPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDE- 572 P Q SP +D + + PP + PE + P S + Sbjct: 1177 TASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPR-ERSGAGSSPETKEQNSALPTSSQD 1235 Query: 573 ------LDETDTPGSEV--GLSSQ-AEATTSTTGEGPECICTQEHGQGPPRKRKRASEPG 623 +++++ P ++ LSS+ E +TS PE P Sbjct: 1236 EELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEV----------------EERPA 1279 Query: 624 DKASKKPSRGRRKLTATEGP------GSPRDAEDHSPSPNS 658 + S+ + L A E P G P + +H NS Sbjct: 1280 VSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNS 1320 >gi|188536004 zinc finger protein 469 [Homo sapiens] Length = 3925 Score = 58.5 bits (140), Expect = 2e-08 Identities = 122/526 (23%), Positives = 178/526 (33%), Gaps = 121/526 (23%) Query: 130 DRPKPRAKEGT-SDPPSPLLL--------PSPGGWKAITEKP--PGGHEEAEEDHQGVGL 178 DRP PR S+ P LL + GW E+P P H + Sbjct: 3461 DRPPPRGSSPILSEGSLPALLHLCSEVAPSTTKGWPETLERPVDPVTHP----------I 3510 Query: 179 RGEEKPAGHRTSPVAKISP-GATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRG 237 RG E P+ H+ P +SP A L + R L G A+ RP ++A P G Sbjct: 3511 RGCELPSNHQECPPPSLSPFPAALADGRG--------DCALDG--ALERPENEASPGSPG 3560 Query: 238 PANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLS 297 P LP +S P P RG + + + + + +P C + Sbjct: 3561 PL--LQQALPLGASLPRPG-ARGQDAEG-----KRAPLVFSGKRRAPGARGRCAPDHFQE 3612 Query: 298 LHL----QSPHSSPLAPAAAP---------SDPRLQDLKAREAEAWEEPTELLGLPSALA 344 HL + SS + P + P +++ A P++ L P Sbjct: 3613 DHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP---- 3668 Query: 345 GMQDLRLEGALHLLLAQQQLRARARAGSVRPR--GQPTPGEMLPSLPVGSDSEGPENEGT 402 + R GS+ P + T M P+ P GP ++G+ Sbjct: 3669 -------------------VHPRKAVGSLAPGELARGTENGMKPATPKAKP--GPSSQGS 3707 Query: 403 RAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDT-----PK 457 + GG QPA G+ Q A + E AR Q P+ Sbjct: 3708 GSPRPGTKTGGGSQPQPAS-GQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKGPR 3766 Query: 458 PAGQ---HGSLSPAAAHTASPEP-------PTQSGPLTRSPQALSNGTKGTRVPEQEEAS 507 AG+ HGSL P +S + P +S + +A S K R P ++ Sbjct: 3767 EAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATP 3826 Query: 508 TPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ---PPPHPQPPDLDGHPEPSKAE 564 + + P++P P SQ +P PPP Q P H Q D G P Sbjct: 3827 SRVLPTKPKPNSQ--------------NKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRP 3872 Query: 565 VLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQ 610 +LRP G+ V + AE T T E + +Q GQ Sbjct: 3873 LLRPPK--------RGTAVHGAEPAEPHTHRTAEAQSDLLSQLFGQ 3910 Score = 54.3 bits (129), Expect = 4e-07 Identities = 143/555 (25%), Positives = 191/555 (34%), Gaps = 106/555 (19%) Query: 112 KEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKP--PGGHEEA 169 + E + EE+ R + P + P + P+PG ++ P PG + E Sbjct: 168 RTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEY 227 Query: 170 EEDHQGVGLRGEEK--PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQ-----LHGTI 222 + E P + P A+ P +P+ P SP+ +S Q LHG Sbjct: 228 QASGADSWPPAAENSFPGANFGVPPAEPEP---IPKGSRPGGSPRGVSFQFPFPALHGAS 284 Query: 223 AVVRPGSQACPA-DRGP---------------ANGTPP--PLPARSSP-PSPAYER---G 260 P A A GP A GT P PLP + +P P P Y+ G Sbjct: 285 TKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGG 344 Query: 261 LSLDSFLRASRPS-AMTHEAPKLSPKVDRL------CLLNRPLSLH-----LQSPHSS-- 306 L+ S L + S H AP+ P D L L RP S + P SS Sbjct: 345 LNRHSDLSGALSSPGAAHSAPR--PFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP 402 Query: 307 --------------------PLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSA--LA 344 P AAP P AR + W+ P LA Sbjct: 403 QRHFPGQAYRASGVDTSPGPPDTELAAPGPP-----PARLPQLWDPTAAPYPTPPGGPLA 457 Query: 345 GMQDLRLEG----ALHLLLAQQQLRARARAGSVRPRGQPTPG--EMLPSLPVGSDSEGPE 398 + + G L L Q A V P +P+P EML LP + GPE Sbjct: 458 ATRSMFFNGQPSPGQRLCLPQS---APLPWPQVLPTARPSPHGMEMLSRLPFPAG--GPE 512 Query: 399 NEG-TRAALAAAGLSGG-RHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTP 456 +G ++ AL AG + G R PA + A T + D +G A+ Q +P Sbjct: 513 WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572 Query: 457 KPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514 HG SL P ASP P T + + T + P + P Sbjct: 573 -----HGTPSLPPPRVVGASPSESPLPSPATNT----AGSTCSSLSPMSSSPANPSSEES 623 Query: 515 PLPGSQ-LSLSSPGSTEDEDTGRPLPPPHPQP--PPHPQPPDLDGHPEPSKAEVLRPESD 571 LPG S T ++TG P P P P P H QP P P+ Sbjct: 624 QLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEGAFQ 683 Query: 572 ELDETDTP--GSEVG 584 L+ET P G EVG Sbjct: 684 CLEETPFPHEGPEVG 698 Score = 45.8 bits (107), Expect = 1e-04 Identities = 131/535 (24%), Positives = 183/535 (34%), Gaps = 89/535 (16%) Query: 151 SPGGWKAITEKPPGGHEEAEEDHQGVGLRGE-EKPAGHRTS----PVAKISPGATLPESR 205 SPGG + T GH+ E GL G+ EK G T+ P +SPG T + Sbjct: 1930 SPGGVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPENGVSPGGTDNHAS 1989 Query: 206 APDMSPQRISNQLHGTIAVVR-PGSQACPADRGPANGTPPPLPARSSPPSPAYER-GLSL 263 ++ G + + + GS+A + + A TP SPPSP E L+L Sbjct: 1990 VNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTP-------SPPSPNRESLALAL 2042 Query: 264 DSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLK 323 + S T E SP LN+PL SP APS L Sbjct: 2043 TAAHSRSGSEGRTPERAS-SPG------LNKPLLATGDSP---------APSVGDLAACA 2086 Query: 324 AREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGE 383 A P L LP R +G L QL A S R P P + Sbjct: 2087 PSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLG-----GQLPA-----SPSCRDPPGPQQ 2136 Query: 384 MLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLD 443 +L P + E E +G +A G P P + T C P + Sbjct: 2137 LLACSPAWAPLE--EADGVQATTDT-----GAEDSPVAP------PSLTTSPC---DPKE 2180 Query: 444 LSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ 503 +G+ +P +A T + T R P+ ++ ++ E Sbjct: 2181 ALAGCLLQGEGSPLEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPE----DSRKEKLWES 2236 Query: 504 EEASTPMDPSRPLPGS--------QLSLSSPGSTEDEDTGRPLPPPHPQ---PPPHPQPP 552 +T S PL G+ LSS + ++ GR LP P PQ PPH P Sbjct: 2237 PGRAT----SPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAPPHTNPD 2292 Query: 553 DLD-GHPEPSKAEVLRPESDELDETDTPGSE------VGLSSQA--EATTSTTGEGPECI 603 + GH S + R E +E G S A E T+ + PE Sbjct: 2293 RMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDP 2352 Query: 604 CTQEHGQGPPRKRKRASEP----GDKASKKPSRGRRKLTATEGPGSPRDAEDHSP 654 T E G+ K R + P G + PS ++ P S R+A +P Sbjct: 2353 GTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF-QSDSPQSHRNASHQTP 2406 Score = 43.9 bits (102), Expect = 5e-04 Identities = 107/484 (22%), Positives = 149/484 (30%), Gaps = 113/484 (23%) Query: 167 EEAEEDHQGVGLRGEEKPAGHR---TSPVAKISPGATLPESRAPDMSPQRISNQLHGTIA 223 + E D + + +E+P+G R + K G T PES+AP P + Sbjct: 856 DNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVT-PESKAPPPLPAATPDP-----Q 909 Query: 224 VVRPGSQACPADRGPANGTPPPLPARSSPPSPAYE--RGLSLDSF--------------- 266 RPG + CPA P + P + PS + RG L F Sbjct: 910 TPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGS 969 Query: 267 --------LRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS----SPLAPAAAP 314 LR R + P RP Q+P S +P P AA Sbjct: 970 GGGGRASGLRPRRNDGLGERPPP------------RPRRPRTQAPGSRADPAPRVPRAAA 1017 Query: 315 SDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVR 374 + + R ++P + A E L ++ + +LR A Sbjct: 1018 LPEETRSSRRRRLPPRKDPRKRKARGGAWGK------ELILKIVQQKNRLREYDFASESE 1071 Query: 375 PRGQPTP-----------GEMLPSLPVGSDSEGPENEGTR-AALAAAGLSG--------- 413 QP P GE + + E + R AA AG G Sbjct: 1072 EDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPG 1131 Query: 414 ------GRHTQPAGPGRAQRTEAAATQ---------DCALDKPLDLSEWGRARGQDTPKP 458 GR Q GP R+ T AAA + A PL + + P Sbjct: 1132 GSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRPSL 1191 Query: 459 AGQHGSLSPAAAHTASPE-----------PPTQSGPLTRSPQAL-------SNGTKGTRV 500 + P A ++P+ P +G + SP L S GT Sbjct: 1192 DFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPSRHDTGTPK 1251 Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQP---PDLDGH 557 P A+T S P PG L PG T+ + PP QP P P Sbjct: 1252 PSGSLANTAPHGSSPTPGVGSLLGGPGGTQAPVSHNSKDPPARQPGEFLAPVANPSSTAC 1311 Query: 558 PEPS 561 P+PS Sbjct: 1312 PKPS 1315 Score = 41.2 bits (95), Expect = 0.003 Identities = 122/535 (22%), Positives = 165/535 (30%), Gaps = 111/535 (20%) Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTP 243 P T P SP S PD+ R L+G+++ R A P Sbjct: 1406 PGTAETEPGRAASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPF------ACADP 1459 Query: 244 PPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP 303 P S PP P++ L P +H KV L P Sbjct: 1460 PQKTVPSDPPYPSF-------LLLEEVSPMLPSHFPDLSGGKV-----------LSKTCP 1501 Query: 304 HSSPLAPAAAPSDP---------RLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354 + P AAPS P + L E E + TE L S L +D R Sbjct: 1502 PERTVVPGAAPSLPGKGSGCSVALMSHLSEDELEIQKLVTE---LESQLQRSKDTR-GAP 1557 Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE-------GPENEGTRAALA 407 L A+ R G+ P + T +P S ++ EG +A+A Sbjct: 1558 RELAEAESVGRVELGTGTEPPSQRRTCQATVPHEDTFSAADLTRVGESTAHREGAESAVA 1617 Query: 408 AA----GLSGGRHTQPAG--PGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQ 461 G GG PA PG A A +D P Q K Sbjct: 1618 TVEAVQGRPGGTWPCPASFHPGHAALL-PCAQEDLVSGAPFS-PRGANFHFQPVQKAGAS 1675 Query: 462 HGSLSPAAAHT------ASPEPPTQSGP-LTRSPQALSNGTKGTRVPEQEEASTPM---D 511 L A + PEP Q GP L A + + P+ +EA++ D Sbjct: 1676 KTGLCQAEGDSRPPQDVCLPEPSKQPGPQLDAGSLAKCSPDQELSFPKNKEAASSQESED 1735 Query: 512 PSRPLPGSQLS--LSSPGSTEDEDTGRPLPPPHPQPPPHPQP---------PDLD----- 555 R LP Q L PG+ + G P P P H P P LD Sbjct: 1736 SLRLLPCEQRGGFLPEPGTADQPHRGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATWPF 1795 Query: 556 ---------GHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEG------- 599 GH L P + PG E + A A++ T G Sbjct: 1796 GASPSHAAQGHSAGRAGGHLHPTAGR------PGFEGNEFAPAGASSLTAPRGREAWLVP 1849 Query: 600 ---PECIC-------TQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLT-ATEGP 643 P C+ +Q+ PP ++ + PG SK G ++LT A + P Sbjct: 1850 VPSPACVSNTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSP 1904 Score = 35.0 bits (79), Expect = 0.22 Identities = 139/600 (23%), Positives = 180/600 (30%), Gaps = 147/600 (24%) Query: 146 PLLLPSPGGWKAITEKP-PGGHEEAEEDHQG-VGLRG------EEKPA------------ 185 P PSP G + ++ P P G E + QG +G G E+ PA Sbjct: 489 PTARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALF 548 Query: 186 --GHRTSPVAK----------ISPGAT--LPESRAPDMSPQRISNQLHGTIAVVRPGSQA 231 T P A+ +SP T LP R SP T S Sbjct: 549 TYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSL 608 Query: 232 CPADRGPANGT-----------------PPPLPARSSPPSPAYERGLSLDSFLRASRPSA 274 P PAN + PP P + P P+ E SL + + A Sbjct: 609 SPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAKA 668 Query: 275 MTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSP-LAPAAAPSDPRLQDLKAREAEAWEEP 333 A L + CL P PH P + PR P Sbjct: 669 FPFPADGLGAEGAFQCLEETPF------PHEGPEVGRGGLQGFPRAPP---------PYP 713 Query: 334 TELLGLPSALAGMQDLRLE--------GALHLLLAQQQ----LRARARAGSVRPRGQPTP 381 T L SA D+ L +L LA +Q L ARA+ G R G P Sbjct: 714 THHFSLSSASLDQLDVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPG- 772 Query: 382 GEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKP 441 LPS P + G LS + AG +A+ D P Sbjct: 773 ---LPSPPAAPRVPADAHAGL--------LSHAKTFLLAGDAQAE----------GKDDP 811 Query: 442 LDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVP 501 L P PA A + E + +P+ S+ V Sbjct: 812 LRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEALNGMEYQSDNPEIDSSFID---VF 868 Query: 502 EQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPS 561 EE S P PS P L S E PPP P P PQ P P+ Sbjct: 869 ADEEPSGPRGPSSGHP-----LKSKAGVTPESKA---PPPLPAATPDPQTPRPGDRGCPA 920 Query: 562 KAEVLRPESDEL----DETDTPGS-------------EVGLSSQAEATTSTTGEGPECIC 604 + RP++ L E D P L S A S +G G Sbjct: 921 RG---RPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGG----- 972 Query: 605 TQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEET 664 G+ + +R G++ +P R R T+ PGS D P + P EET Sbjct: 973 ----GRASGLRPRRNDGLGERPPPRPRRPR-----TQAPGSRADPAPRVPRAAALP-EET 1022 Score = 32.0 bits (71), Expect = 1.9 Identities = 99/404 (24%), Positives = 131/404 (32%), Gaps = 82/404 (20%) Query: 168 EAEEDHQ----GVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIA 223 E+EED Q G G RG R P P+ P++ + Q G Sbjct: 1069 ESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQK------PRKAARQEAGGDG 1122 Query: 224 VV---------RPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSA 274 RPG P RGP+ AR P A Sbjct: 1123 APANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCA------------------ 1164 Query: 275 MTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAA-APSDPRLQDLKAREAEAWEEP 333 + P ++PK PL + + S P+ P + + + A E Sbjct: 1165 ---DRPSVAPK--------DPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEF 1213 Query: 334 TELL-GLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRG---QPTPGEMLPSLP 389 TE L P+A AG + + LL+ +Q +R G+ +P G P P+ Sbjct: 1214 TEALRSPPAACAG----EMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPG 1269 Query: 390 VGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGR 449 VGS GP GT+A +S PA A A KP LS Sbjct: 1270 VGSLLGGP--GGTQAP-----VSHNSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKIS 1322 Query: 450 ARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGP---LTRSPQALSNGTKGTRVPEQEEA 506 + G D PAG + P A P S P L P+ L+ P+ Sbjct: 1323 SFGCD---PAG--FNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLAGCFLEELHPKPSAR 1377 Query: 507 STPMDPSRPL------PGS---QLSLSSPGSTEDEDTGRPLPPP 541 P S L GS QL S PG+ E E GR PP Sbjct: 1378 DAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETE-PGRAASPP 1420 Score = 30.0 bits (66), Expect = 7.1 Identities = 45/203 (22%), Positives = 71/203 (34%), Gaps = 18/203 (8%) Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKG---TRVPEQEEASTPMDPSRPLPGSQLSLSS 525 A+ + E P GP R + K T+ P ++E P +R G + Sbjct: 1067 ASESEEDEQPPPRGPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGD---GA 1123 Query: 526 PGSTEDEDTGRPLPPPHPQPPPHPQPPDL-----DGHPEPSKAEVLRPESDELDETDTPG 580 P + E+ RP P PQ + + +G P+ + + P+ T+T Sbjct: 1124 PANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTET 1183 Query: 581 SE---VGLSSQAEATTSTTGE--GPECICTQEHGQGPPR--KRKRASEPGDKASKKPSRG 633 SE L EA T E P+ E + PP + + PG ++P Sbjct: 1184 SEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAACAGEMGASPGLLIPEQPPPS 1243 Query: 634 RRKLTATEGPGSPRDAEDHSPSP 656 R + GS + H SP Sbjct: 1244 RHDTGTPKPSGSLANTAPHGSSP 1266 Score = 30.0 bits (66), Expect = 7.1 Identities = 37/145 (25%), Positives = 54/145 (37%), Gaps = 20/145 (13%) Query: 456 PKPAGQHGSLSPAAAHTASP-EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSR 514 P P G SPAA P EP Q + P+ S+ G P P ++ Sbjct: 2469 PHP-GAPAEPSPAALPAQQPLEPLAQK---CQPPRKKSHRVSGKERPNHSRGD-PSHVTQ 2523 Query: 515 PLP--GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDE 572 P P GS+ L +PGS + P P H + P P+ ++ + L P+ E Sbjct: 2524 PPPAQGSKEVLRAPGSPHSQQLHPPSPTEH---EVDVKTPASKPRPDQAREDELHPKQAE 2580 Query: 573 LDE---------TDTPGSEVGLSSQ 588 E D+P G S++ Sbjct: 2581 KREGRRWRREPTVDSPSHSEGKSNK 2605 >gi|116256445 nuclear receptor co-repressor 2 isoform 2 [Homo sapiens] Length = 2462 Score = 57.8 bits (138), Expect = 3e-08 Identities = 50/231 (21%), Positives = 88/231 (38%), Gaps = 17/231 (7%) Query: 424 RAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGP 483 + ++ AAA+++ A ++ E + +G + A T + T+S P Sbjct: 682 KKKKAPAAASEEAAFPPVVEDEE------MEASGVSGNEEEMVEEAEATVNNSSDTESIP 735 Query: 484 LTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHP 543 + A G G + P A P P + + + E TG P PP P Sbjct: 736 SPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATGAPTPP--P 793 Query: 544 QPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECI 603 PP PP + E + P +E +E P +E + T E + Sbjct: 794 APPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAE-----ELAVDTGKAEEPVKSE 848 Query: 604 CTQEHGQGPPR----KRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAE 650 CT+E +GP + + A+ G ++K G + T + G+P+D++ Sbjct: 849 CTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSD 899 Score = 40.0 bits (92), Expect = 0.007 Identities = 121/565 (21%), Positives = 181/565 (32%), Gaps = 109/565 (19%) Query: 28 ELNSERCRDAQRIEELFS-----KNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQEL 82 E NSE Q+ EL S + E+ +T K+ L LE+ R + ++ + Sbjct: 589 EANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGL--LEHGRNWSAIARMVGSKTV 646 Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKE---- 138 ++ + F QNL I + +++ KE N K++ + P E Sbjct: 647 SQCKNFYFNYKKRQNLDEI-LQQHKLKMEKERNARRKKKKAPAAASEEAAFPPVVEDEEM 705 Query: 139 ---GTSDPPSPLLLPSPG--GWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVA 193 G S ++ + + TE P H EA +D G G + PA Sbjct: 706 EASGVSGNEEEMVEEAEATVNNSSDTESIPSPHTEAAKD---TGQNGPKPPA-------- 754 Query: 194 KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPP 253 + GA P P P+ I T PA TPPP P S P Sbjct: 755 --TLGADGPPPGPPTPPPEDIPAPTEPT-----------PASEATGAPTPPPAPPSPSAP 801 Query: 254 SPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA 313 P + + A+ P E K P + L + + P S A Sbjct: 802 PPVVPKEEKEEE--TAAAPPVEEGEEQK-PPAAEELAVDTG----KAEEPVKSECTEEAE 854 Query: 314 PSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSV 373 + +D +A EA A EGAL A+++ RA + Sbjct: 855 EGPAKGKDAEAAEATA----------------------EGALK---AEKKEGGSGRATTA 889 Query: 374 RPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433 + G P + + E + R L P G RA Sbjct: 890 KSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPRPSL-----LTPTGDPRA-------- 936 Query: 434 QDCALDKPLDLSEWGRARG-----QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSP 488 + + KPLDL + + Q T +P +P PP P + +P Sbjct: 937 -NASPQKPLDLKQLKQRAAAIPPIQVTKVHEPPREDAAPTKPAPPAPPPPQNLQPESDAP 995 Query: 489 QALSNGTKG----TRVPEQEEASTPM-DPSRPLPGSQLSLSSPGSTEDEDTGRPLP-PPH 542 Q + +G P +EA P+ P+ +L PG +G P P PP Sbjct: 996 QQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKL----PGDPPCWTSGLPFPVPPR 1051 Query: 543 PQPPPHPQPPDLD-------GHPEP 560 P PD GHP P Sbjct: 1052 EVIKASPHAPDPSAFSYAPPGHPLP 1076 Score = 34.7 bits (78), Expect = 0.29 Identities = 67/319 (21%), Positives = 99/319 (31%), Gaps = 77/319 (24%) Query: 377 GQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDC 436 G PTP PS P P+ E AA + G +P + ++ Sbjct: 787 GAPTPPPAPPS-PSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPA-AEELAVDTGKAEEP 844 Query: 437 ALDKPLDLSEWGRARGQDTP----------KPAGQHGSLSPAAAHTASPEPPTQSGPLTR 486 + + +E G A+G+D K + G A +S P T Sbjct: 845 VKSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 904 Query: 487 SPQALSN---GTKGTRVPEQEEASTPM-------DPSRPLPGSQLSLSSPGSTEDEDTGR 536 S + G K + + TP P +PL QL + + T Sbjct: 905 SADEVDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKV 964 Query: 537 PLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTT 596 PP P P PP P + L+PESD Sbjct: 965 HEPPREDAAPTKPAPP------APPPPQNLQPESD------------------------- 993 Query: 597 GEGPECICTQEHGQGPPRKRKRASEPGDKASKKP------SRGRRKLTA-----TEG--- 642 Q+ G P K + + P DK ++KP + +KL T G Sbjct: 994 -------APQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPF 1046 Query: 643 PGSPRD---AEDHSPSPNS 658 P PR+ A H+P P++ Sbjct: 1047 PVPPREVIKASPHAPDPSA 1065 Score = 32.7 bits (73), Expect = 1.1 Identities = 55/285 (19%), Positives = 89/285 (31%), Gaps = 38/285 (13%) Query: 375 PRGQPTPGEMLPSLPVGSDSEG-PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAAT 433 P G PTP P + + +E P +E T A P P + E AA Sbjct: 762 PPGPPTP----PPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAAA 817 Query: 434 QDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSN 493 P++ G++ PA + A T E P +S + + + Sbjct: 818 P------PVE-------EGEEQKPPAAEE-----LAVDTGKAEEPVKSECTEEAEEGPAK 859 Query: 494 GTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPD 553 G E + + G + S G+ +D D+ + Sbjct: 860 GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC-----------SADE 908 Query: 554 LDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATT--STTGEGPECICTQEHGQG 611 +D K +L P L T P + + P T+ H Sbjct: 909 VDEAEGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIQVTKVHE-- 966 Query: 612 PPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSP 656 PPR+ ++P A P + + A + PGS + SP+P Sbjct: 967 PPREDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAP 1011 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 57.0 bits (136), Expect = 5e-08 Identities = 122/503 (24%), Positives = 185/503 (36%), Gaps = 76/503 (15%) Query: 204 SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSL 263 S AP Q Q+ ++A +Q+ PA GPA T L + PPS A + Sbjct: 543 SAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTV--LQGVTLPPS-AVAMLNTP 599 Query: 264 DSFLRASRPSAMTHEAPKL---SPKVDRLCLLNRPLSLHLQSPHSS--PLAP---AAAPS 315 D ++ + P+A T EA + P ++ PL L LQ P + P AP AAAP Sbjct: 600 DGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP- 658 Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARA----- 370 P+ + A +LG P + A + + +L + L Q++ + A Sbjct: 659 -PQATTPQPSPGLASSPEKIVLGQPPS-ATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716 Query: 371 ---GSVRPRGQPTPGEMLPSLPV----GSDSEGPENEGTRAAL----AAAGLSG-GRHTQ 418 SV P + P+ PV G + P+++ + A AAA L G G + Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSS 776 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPE-- 476 P+ P +A ++ +P +R Q +P + L P A P Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSRPP---SRPQSVSRPPSEP-PLHPCPPPQAPPTLP 832 Query: 477 -----------PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSS 525 PP S P +P + P+ + P+ P+ LP S S + Sbjct: 833 GIFVIQNQLGVPPPASNPAPTAPGPPQPPLR----PQSQPPEGPLPPAPHLPPSSTSSAV 888 Query: 526 PGSTEDEDTGRPLPPPHPQ------PP---PHPQ---PPDLDGHPEPSKAEVLRPESDEL 573 S+E T LP P P PP PH PP L PEP+ P + ++ Sbjct: 889 ASSSE---TSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQM 945 Query: 574 DETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRG 633 T P Q +A + P I Q G P + ++ G S S Sbjct: 946 VTTPFPA-----LPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAAS-- 998 Query: 634 RRKLTATEGPGSPRDAEDHSPSP 656 L + + P A H+P+P Sbjct: 999 --VLVSGQAPSGTPTAPSHAPAP 1019 Score = 42.4 bits (98), Expect = 0.001 Identities = 80/350 (22%), Positives = 120/350 (34%), Gaps = 36/350 (10%) Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWE 331 P+ T AP P L++P+S+HL + SS + PA P A A + Sbjct: 428 PATTTGAAPPQPPGA-----LSKPMSVHLLNQGSSIVIPAQHML-PGQNQFLLPGAPAVQ 481 Query: 332 EPTELLGLPSALAGMQDLRLEGALHL--------LLAQQQLRARARAGSV-RPRGQPTPG 382 P +L LP+ + G + A H +L Q L G V P Sbjct: 482 LPQQLSALPANVGG--QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAPHSGAHSA 539 Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCAL---- 438 +L + P+ P +LAA L PAGP + A+ Sbjct: 540 HILSAAPIQVGQ--PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLN 597 Query: 439 --DKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASP----EPPTQSGPLTRSPQALS 492 D + + A G+ P Q +P A T P +P Q P +PQA + Sbjct: 598 TPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAA 657 Query: 493 NGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552 T P AS+ P + + G S + + LP Q P + P Sbjct: 658 PPQATTPQPSPGLASS---PEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714 Query: 553 DLDGHPEPSKAEVLRPESDELDETDTPGSE-VGLSSQAEATTSTTGEGPE 601 L P+ V P + TP ++ GL QA + ++ P+ Sbjct: 715 HLS---VPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQ 761 >gi|91208420 bassoon protein [Homo sapiens] Length = 3926 Score = 56.2 bits (134), Expect = 9e-08 Identities = 133/569 (23%), Positives = 199/569 (34%), Gaps = 120/569 (21%) Query: 135 RAKEGTSDPPSPLLLPSPGGWKAITEKPPGG--HEEA------EEDHQGVGLRGEEKPAG 186 R EG+ P+PL P+ +++PP G H + ++ QG+G PA Sbjct: 519 RLLEGSLGEPTPLPPPT-------SQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPA- 570 Query: 187 HRTSPVA-KISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPP 245 + SP++ K SP LP +P P R S P S R P P P Sbjct: 571 -KASPLSTKASP---LPSKASPQAKPLRASEPSK------TPSSVQEKKTRVPTKAEPMP 620 Query: 246 LPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS 305 P + P+PA + + S +R + P+ +A +PK + Sbjct: 621 KPPPETTPTPATPK---VKSGVRRAEPATPVVKAVPEAPKGGEA-----------EDLVG 666 Query: 306 SPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLR 365 P + A+ S L D +E+ G+ QQ++ Sbjct: 667 KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGV--------------------VQQEVE 706 Query: 366 ARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQP--AGPG 423 AG P P+P E+ VGS R L A GL+ ++P +G G Sbjct: 707 QLDSAGVTGPH-PPSPSEIHK---VGSSM--------RPLLQAQGLAPSERSKPLSSGTG 754 Query: 424 RAQR--------TEAAATQDCALDKPL----DLSEWGRARGQ-DTPKPAGQHGSL----- 465 Q+ T A D L+ L D +EW R R Q DT + + GS Sbjct: 755 EEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDY 814 Query: 466 ----SPAAAHTASPEPPTQSGPLTRSP----QALSNGTKGTRVPEQEEASTPMDPSRPLP 517 S P+PP ++ LT Q L + + E + A+ Sbjct: 815 VEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTAT---------- 864 Query: 518 GSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD 577 S L+ G+ + G P P P P P P H + E L PE + TD Sbjct: 865 -SGRGLAKHGTQK----GGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATD 919 Query: 578 TPGS-EVGLSSQAEATTSTTGE-GPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRR 635 G+ + GL ++TG G E Q G P R+ E R R Sbjct: 920 GSGTLQGGLRRFKTIELNSTGSYGHELDLGQ--GPDPSLDREPELEMESLTGSPEDRSRG 977 Query: 636 KLTATEGPGSPRDAEDHSPSPNSSPWEET 664 + ++T +P SP+ SS E++ Sbjct: 978 EHSSTLPASTPSYTSGTSPTSLSSLEEDS 1006 Score = 44.3 bits (103), Expect = 4e-04 Identities = 134/608 (22%), Positives = 205/608 (33%), Gaps = 128/608 (21%) Query: 105 TNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPG 164 ++E L+EE E L+E+ K V R + A++ D + ++ PP Sbjct: 1040 SSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRR----RERSKTPPS 1095 Query: 165 GHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATL-PESRAPDMSPQRISNQLHGTIA 223 E+ LR + S ++ SP +L E+ A D P R+ Sbjct: 1096 NLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRL--------- 1146 Query: 224 VVRPGSQ-ACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282 + GS+ P + T P + ++P S RP EA + Sbjct: 1147 -YKSGSEYNLPTFMSLYSPTETPSGSSTTPSS---------------GRPLKSAEEAYEE 1190 Query: 283 SPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPR------LQDLKAREAEAWEEPTEL 336 + L + + + PH P + P+ PR QD RE +P Sbjct: 1191 MMRKAELLQRQQGQAAGARGPHGGP----SQPTGPRGLGSFEYQDTTDREYGQAAQPA-A 1245 Query: 337 LGLPSALA------------GMQDLRLEGALHLLLAQQQLRAR-------ARAGSVRPRG 377 G P++L + +R + L A+ + + + A ++ G Sbjct: 1246 EGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNG 1305 Query: 378 QP-TPGEMLPSL--------PVGSDSEG----PENEGTRAALAAAGLSGGRHTQPAGPGR 424 P TPG L P SDS G P+ T+ H+ PA P Sbjct: 1306 GPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSS 1365 Query: 425 AQR------TEAAATQDCALDKPLDLSEWGRARGQDTP-KPAGQHGSLSPAA-AHTASPE 476 A + ++ T P G RG TP PAG S SP++ AH+ Sbjct: 1366 ASKEIGMPFSQGPGTPATTAVAPCPA---GLPRGYMTPASPAGSERSPSPSSTAHSYGHS 1422 Query: 477 PPT-----QSGPLTRSPQAL--------------SNGTKGTRVPEQ-----EEASTPMDP 512 P T Q+ L ++P L S+G GT P + +S P+ P Sbjct: 1423 PTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP 1482 Query: 513 SRPLPGSQLS--LSSPGSTEDEDTGRPLPPPHPQPP-----PHPQPPDLDGHPEPSKAEV 565 S P S P +T + T P P P P P P P G P + Sbjct: 1483 SSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPST 1542 Query: 566 LRPESDELDETDTPGSEVGLSSQAEATT----STTGEGPECICTQ----EHGQG---PPR 614 R E + + P + L+S A + T ++ P C T+ HG PP Sbjct: 1543 PRLVWQESSQ-EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601 Query: 615 KRKRASEP 622 + EP Sbjct: 1602 VSQLPPEP 1609 Score = 40.4 bits (93), Expect = 0.005 Identities = 82/340 (24%), Positives = 108/340 (31%), Gaps = 78/340 (22%) Query: 150 PSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDM 209 P G W E PG H A+E G R + G PG + A D+ Sbjct: 3624 PEEGLWPH-DEGGPGRHASAKEHRHGDHGRHSGRHTGEE--------PGRRAAKPHARDL 3674 Query: 210 SPQRISNQLHGTIAVVRPGSQACPADRGPANGTPP-PLPARSSPPSPAYERGLSLDSFLR 268 RP SQ A P G P P A S PS A + Sbjct: 3675 GRHE-----------ARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK 3723 Query: 269 ASR-----PSAMTHEA-PKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDL 322 SR P+A+ +A P+ P++ P QSP S + AA P+ Q Sbjct: 3724 GSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQS--QSPSSRQIPSGAASRQPQTQ-- 3779 Query: 323 KAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPG 382 + + LGL + RL+ +Q R A A S +P G+P PG Sbjct: 3780 ---------QQQQGLGLQPPQQALTQARLQQQ-----SQPTTRGSAPAAS-QPAGKPQPG 3824 Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPL 442 S + GP QPAGP RA++T + K Sbjct: 3825 P--------STATGP--------------------QPAGPPRAEQTNGSK----GTAKAP 3852 Query: 443 DLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSG 482 +A+ P PAG P A P G Sbjct: 3853 QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADG 3892 Score = 38.1 bits (87), Expect = 0.026 Identities = 39/152 (25%), Positives = 54/152 (35%), Gaps = 24/152 (15%) Query: 512 PSRPLPGSQLSLSSPGSTEDEDTG-RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPES 570 PS P G QL P + T P+P P P P P P P +P + P Sbjct: 37 PSAPAGGGQL----PAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKE-----PLG 87 Query: 571 DELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK---RASEPGDKAS 627 ++ + TP + E+ T +GP + GP R + R G S Sbjct: 88 NQRAASPTPKQASATTPGHESPRETRAQGP----AGQEADGPRRTLQVDSRTQRSGRSPS 143 Query: 628 KKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 P RG P SP +P P+S+ Sbjct: 144 VSPDRG-------STPTSPYSVPQIAPLPSST 168 Score = 38.1 bits (87), Expect = 0.026 Identities = 127/514 (24%), Positives = 174/514 (33%), Gaps = 66/514 (12%) Query: 168 EAEEDHQGVGLRGEEKPAGHRTSP----VAKISPGATLP-ESRAPDMSPQRISNQLHGTI 222 + E D Q G+ G + SP + ++PG E + PD P I Q H Sbjct: 2719 QTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD--PLEIGYQAH--- 2773 Query: 223 AVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282 + P S + R P +P L + SP SP LD+ +S H +P+ Sbjct: 2774 --LPPESLSQLVSRQPPK-SPQVLYSPVSPLSPHR----LLDTSFASSERLNKAHVSPQK 2826 Query: 283 SPKVD---RLCLLNRPL-SLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLG 338 D R L RP+ +L PL+P A S L + + + L Sbjct: 2827 HFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALP- 2885 Query: 339 LPSALAGMQDLRLEGA----LHLLLAQQ---QLRARA--RAGSVRPRGQP-TPGEMLPSL 388 P++L L HL LA Q QL A + + G P P T +L L Sbjct: 2886 -PNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLREL 2944 Query: 389 PVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP-----GRAQRTEAAATQDCALDKP-- 441 D E+E T+ A L A G QR E+ A D P Sbjct: 2945 D--RDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPL 3002 Query: 442 ---------LDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPT-----QSGPLTRS 487 L SE + R Q PAGQ AA A+P PT + P Sbjct: 3003 RGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQ 3062 Query: 488 PQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPG--STEDEDTGRPLPPPHPQP 545 A S G P + + P + P P S P ++ RP Q Sbjct: 3063 YSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT 3122 Query: 546 PPHPQPPDLDGHPEPSKAEVLRPESDELD--ETDTPGSEVGLSS----QAEATTSTTGEG 599 P L P S+A + +P L E P + ++S + A + T+ G Sbjct: 3123 PMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSG 3182 Query: 600 PECICTQEHGQGP--PRKRKRASEPGDKASKKPS 631 P E G+ P PR R S A PS Sbjct: 3183 PAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPS 3216 Score = 37.4 bits (85), Expect = 0.045 Identities = 27/111 (24%), Positives = 44/111 (39%), Gaps = 8/111 (7%) Query: 527 GSTEDEDTGRPLPPPHP------QPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPG 580 G E+ GR PH + PH QP P+ K + P S E + Sbjct: 3655 GRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPK--KGQPGYPSSAEYSQPSRAS 3712 Query: 581 SEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPS 631 S +S ++ + GP + ++ Q P+ + R + PG + S+ PS Sbjct: 3713 SAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPS 3763 Score = 33.9 bits (76), Expect = 0.49 Identities = 46/190 (24%), Positives = 69/190 (36%), Gaps = 21/190 (11%) Query: 375 PRGQPTPGEMLPSLPVG-SDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQR------ 427 P G G P+ SD EG + +RA A S P+ P + Sbjct: 1439 PSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFA--SSSPPLSPSSPSESPTFSPGKM 1496 Query: 428 -TEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASP--EPPTQSGPL 484 A A P S+ R+ G TP P G+ +P T + +Q P Sbjct: 1497 GPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPF 1556 Query: 485 TRSPQALSNGTKGTRVPEQEEASTPM-DPSRPLPGSQ-LSLSSPGSTEDEDTGRPLPPPH 542 A S+ + TR+ +++P+ P+ P + S ++P S LPP Sbjct: 1557 MVITLA-SDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQ------LPPEP 1609 Query: 543 PQPPPHPQPP 552 P PP P+ P Sbjct: 1610 PGPPGFPRVP 1619 Score = 30.0 bits (66), Expect = 7.1 Identities = 52/214 (24%), Positives = 75/214 (35%), Gaps = 37/214 (17%) Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLS-----PAAAHTA--------SPEPPTQSGPLT- 485 +PL + R+RG P+P + + P A A SP+PP + P T Sbjct: 256 QPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTA 315 Query: 486 --RSPQALSNGTKGTRVPEQEEAS--TPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPP 541 R P + T VP A+ T + L G SL + ST L Sbjct: 316 EPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST--------LMSV 367 Query: 542 HPQPPPHPQPPDLDGHP-----EPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTT 596 P+ QP G P + SK +P L PG G ++ A Sbjct: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKP----LGSGPGPGPAPGAKTEPGARMG-P 422 Query: 597 GEGPECICTQEHGQGPPRKRKRASEPGDKASKKP 630 G GP + + G P+ + + KA+ KP Sbjct: 423 GSGPGAL-PKTGGTTSPKHGRAEHQAASKAAAKP 455 >gi|50428935 BPY2 interacting protein 1 [Homo sapiens] Length = 1059 Score = 56.2 bits (134), Expect = 9e-08 Identities = 119/516 (23%), Positives = 173/516 (33%), Gaps = 99/516 (19%) Query: 180 GEEKPAGHRTSPVAKISPGATLPESRAPD------------MSPQRISNQLHGTIAVVRP 227 G+E+P R P +P T E++ P P+ + + + Sbjct: 495 GQERPGVARKEPARAEAPRKTEKEAKTPRELKKDPKPSVSRTQPREVRRAASSVPNLKKT 554 Query: 228 GSQACPADR-GPA---NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS 283 +QA P R P+ +G PP SPPS AS PSA Sbjct: 555 NAQAAPKPRKAPSTSHSGFPPVANGPRSPPSLRCGE---------ASPPSAAC------- 598 Query: 284 PKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSAL 343 SP + A L + A E +A E P +P Sbjct: 599 ---------------------GSPASQLVATPSLELGPIPAGEEKALELPLAASSIPRPR 637 Query: 344 AGMQDLR---LEGALHLLLAQQQLRARARAGSVRPRGQPT---PGEMLPSLP--VGSDSE 395 + EG+ L L+ R G P PT P PSLP VGS Sbjct: 638 TPSPESHRSPAEGSERLSLSP------LRGGEAGPDASPTVTTPTVTTPSLPAEVGSPHS 691 Query: 396 GPENEGTRAALA-----AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRA 450 +E + +A S + P RA+R+ + D L P + R Sbjct: 692 TEVDESLSVSFEQVLPPSAPTSEAGLSLPLRGPRARRSASPHDVDLCLVSPCEFEH--RK 749 Query: 451 RGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPM 510 P PA SP +++ +S ++G L G + T E+ + Sbjct: 750 AVPMAPAPA------SPGSSNDSSARSQERAGGL---------GAEETPPTSVSESLPTL 794 Query: 511 DPSRPLPGSQLSLSSPGSTEDEDTGR--PLPPPHPQPPPHPQPPDL-DGHPEPSKAEVLR 567 S P+P + + S TE R PLP P PPP P P + PE + R Sbjct: 795 SDSDPVPLAPGAADSDEDTEGFGVPRHDPLPDPLKVPPPLPDPSSICMVDPEMLPPKTAR 854 Query: 568 PESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA- 626 +++ + T P + + A T + + + P R SE G +A Sbjct: 855 -QTENVSRTRKPLARPNSRAAAPKATPVAAAKTKGLAGGDRASRPLSARSEPSEKGGRAP 913 Query: 627 -SKKPSRGRRKLTATEGP-GSPRDAEDHSPSPNSSP 660 S+K S + TAT GP GS S +P SP Sbjct: 914 LSRKSSTPK---TATRGPSGSASSRPGVSATPPKSP 946 >gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] Length = 2968 Score = 55.8 bits (133), Expect = 1e-07 Identities = 104/490 (21%), Positives = 175/490 (35%), Gaps = 68/490 (13%) Query: 113 EENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEED 172 ++ +T + + +R+L P K ++P LL+PS T K G ++ Sbjct: 2265 DDGDTGRIPLSHIRLL----PPDYKIQCAEPSPALLVPSAKRRSRKTSKDTGEGKDG--- 2317 Query: 173 HQGVGLRGEEKPA------GHRTSPVAKISPGATLPESRAPDMSPQR-ISNQLHGTIAVV 225 G G E+P G + S AK ATL E D P ++ + T Sbjct: 2318 ----GTAGSEEPGAKARGRGRKPSAKAKGDRAATLEEGNPTDEVPSTPLALEPSST---- 2369 Query: 226 RPGSQACPADRGPANGTPP---PLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKL 282 PGS+ P + P P P + SP PA+ + + F P+ AP + Sbjct: 2370 -PGSKKSPPEPVDKRAKAPKARPAPPQPSPAPPAFTSCPAPEPFAELPAPATSLAPAPLI 2428 Query: 283 S-------PKVDRLCLLN------RP---LSLHLQSPHSSPLAPAAAPSDPRLQDLKARE 326 + PK R + RP L ++ H +P + + L + Sbjct: 2429 TMPATRPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPG 2488 Query: 327 AEAWEEPTELLGL----PSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPG 382 A W+EP LL L P+A + A LAQ+ S P+ P Sbjct: 2489 AGGWQEPKSLLSLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPK-SPDKA 2547 Query: 383 EMLPSLPVGSDSEGPENEGTRAALAAAGLSG--------GRHTQPAGPGRAQRTEAAATQ 434 + S+S + G+ ++ +++ SG G G G R +AA+ Sbjct: 2548 QAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASS 2607 Query: 435 DCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNG 494 A S + + + S S +++ ++S + S + S + S+ Sbjct: 2608 RAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2667 Query: 495 TKGTRVPEQEEASTPMDPSRPL----PGSQLSLSSPGSTE-------DEDTGRPLPPPHP 543 + + E S+ D + P P +Q +L + + + G+ P P P Sbjct: 2668 SSSSTTDEDSSCSSD-DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQP 2726 Query: 544 Q-PPPHPQPP 552 Q PPP P P Sbjct: 2727 QAPPPQPTQP 2736 Score = 47.0 bits (110), Expect = 6e-05 Identities = 59/241 (24%), Positives = 81/241 (33%), Gaps = 47/241 (19%) Query: 436 CALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGT 495 CA P L + R + T K G+ A S EP ++ R P A + G Sbjct: 2288 CAEPSPALLVPSAKRRSRKTSKDTGEGKDGGTAG----SEEPGAKARGRGRKPSAKAKGD 2343 Query: 496 KGTRV----PEQEEASTPM--DPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP 549 + + P E STP+ +PS PGS+ SP D+ P P P P P P Sbjct: 2344 RAATLEEGNPTDEVPSTPLALEPSST-PGSK---KSPPEPVDKRAKAPKARPAP-PQPSP 2398 Query: 550 QPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHG 609 PP P P AE T P + T Sbjct: 2399 APPAFTSCPAPEPF-------------------------AELPAPATSLAPAPLITMPAT 2433 Query: 610 QGPPRKRKRASEPGDKASKKPSRGRRKLTAT--EGPGSPRDAEDHS-----PSPNSSPWE 662 + P+K + A E G K ++P L EG SP+ + P + W+ Sbjct: 2434 RPKPKKARAAEESGAKGPRRPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQ 2493 Query: 663 E 663 E Sbjct: 2494 E 2494 Score = 36.2 bits (82), Expect = 0.100 Identities = 89/356 (25%), Positives = 122/356 (34%), Gaps = 76/356 (21%) Query: 231 ACPADRGPANGTPPPLPARSSPPSPAYERGLSLD---------SFLRASR-PSAMTHEAP 280 A A R PA+G P PLP Y GL+L SF+ + PSA +H +P Sbjct: 32 AATAGRLPASGLPGPLPPGK------YMAGLNLHPHPGEAFLGSFVASGMGPSASSHGSP 85 Query: 281 KLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAA----------PSD--PRLQDLKAREAE 328 P LS +P + P+ A PS P L E Sbjct: 86 VPLPS---------DLSFRSPTPSNLPMVQLWAAHAHEGFSHLPSGLYPSYLHLNHLEPP 136 Query: 329 AWEEPT-ELLGLPSALAGMQDLRLEG-ALHLLLAQQQLRARARAGSVRPRGQPTPGEMLP 386 + P LG PS + G +L A + A S R TPG Sbjct: 137 SSGSPLLSQLGQPSIFDTQKGQGPGGDGFYLPTAGAPGSLHSHAPSAR-----TPG---- 187 Query: 387 SLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSE 446 G S G +G+ + A GR +P + A + +DL++ Sbjct: 188 ----GGHSSGAPAKGSSSRDGPAKERAGRGGEPPPLFGKKDPRARGEEASGPRGVVDLTQ 243 Query: 447 WGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKG-----TRVP 501 RA G+ P LSP A E T++ L S + NG G V Sbjct: 244 EARAEGRQDRGPPRLAERLSPFLA-----ESKTKNAALQPSVLTMCNGGAGDVGLPALVA 298 Query: 502 EQ-----EEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPP 552 E +EA+ + +R L ++ L P RP P P P PP P+ P Sbjct: 299 EAGRGGAKEAARQDEGARLLRRTETLLPGP---------RPCPSPLPPPPAPPKGP 345 Score = 32.7 bits (73), Expect = 1.1 Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 17/130 (13%) Query: 135 RAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAK 194 R K+G +P L P+PG P E+ + LRG ++P Sbjct: 1931 RPKKGLGEPGPSLAAPTPGARGPDPSSPDKAKLAVEKGRKARKLRGPKEPGFEAG----- 1985 Query: 195 ISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPS 254 PE+ D+ +R S ++ + S A PA A T A+ P S Sbjct: 1986 -------PEASDDDLWTRRRSERI-----FLHDASAAAPAPVSTAPATKTSRCAKGGPLS 2033 Query: 255 PAYERGLSLD 264 P + G + D Sbjct: 2034 PRKDAGRAKD 2043 Score = 32.3 bits (72), Expect = 1.4 Identities = 86/344 (25%), Positives = 118/344 (34%), Gaps = 72/344 (20%) Query: 295 PLSLHLQSP--------HSSPLAPAAAPSDPRLQDLKARE-AEAWEEPTELLGLPSALAG 345 P SLH +P HSS APA S +D A+E A EP L G A Sbjct: 173 PGSLHSHAPSARTPGGGHSSG-APAKGSSS---RDGPAKERAGRGGEPPPLFGKKDPRAR 228 Query: 346 MQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE---------- 395 ++ G ++ Q+ RA R + RG P E L S ++ Sbjct: 229 GEEA--SGPRGVVDLTQEARAEGR----QDRGPPRLAERLSPFLAESKTKNAALQPSVLT 282 Query: 396 ----GPENEGTRAALAAAGLSGGRHT--QPAGPGRAQRTEAAATQDCALDKPLDLSEWGR 449 G + G A +A AG G + Q G +RTE PL Sbjct: 283 MCNGGAGDVGLPALVAEAGRGGAKEAARQDEGARLLRRTETLLPGPRPCPSPLP------ 336 Query: 450 ARGQDTPKPAGQHG-----SLSPAAAHTASPE-------------PPTQSGPLTRSPQAL 491 P PA G + +PA +T E P ++ P + Sbjct: 337 ------PPPAPPKGPPAPPAATPAGVYTVFREQGREHRVVAPTFVPSVEAFDERPGPIQI 390 Query: 492 SNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSP-GSTEDEDTGRPLPPPHPQPPPHPQ 550 ++ + R E+E A P P PGS L P G E R L P P P + Sbjct: 391 ASQARDARARERE-AGRPGVLQAP-PGSPRPLDRPEGLREKNSVIRSLKRPPPADAPTVR 448 Query: 551 PPDLDGHPE---PSKAEVLRPESDELDETDTPGSEVGLSSQAEA 591 P P+K E+L+PE+D P G ++Q A Sbjct: 449 ATRASPDPRAYVPAK-ELLKPEADPRPCERAPRGPAGPAAQQAA 491 Score = 31.2 bits (69), Expect = 3.2 Identities = 73/327 (22%), Positives = 104/327 (31%), Gaps = 74/327 (22%) Query: 380 TPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALD 439 TP + PS GS PE RA A +PA P + A + C Sbjct: 2360 TPLALEPSSTPGSKKSPPEPVDKRAKAPKA--------RPAPPQPSPAPPAFTS--CPAP 2409 Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499 +P + P PA SL+PA T P T+ P ++ A +G KG R Sbjct: 2410 EPF----------AELPAPAT---SLAPAPLITM---PATRPKP-KKARAAEESGAKGPR 2452 Query: 500 VP----------EQEEASTPM------------DPSR---PLPGSQLSLSS-PGSTEDED 533 P + E ++P DP P S LSL S P + + Sbjct: 2453 RPGEEAELLVKLDHEGVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAGSSE 2512 Query: 534 TGRPLPPPHP-----QPPPHPQPPDLDGHPEPSKAEVLR--PESDELDETDTPGSEVGLS 586 P P +P P D P KA+ + E E + + GS S Sbjct: 2513 PKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSS 2572 Query: 587 SQAEATTSTTGE--------------GPECICTQEHGQGPPRKRKRASEPGDKASKKPSR 632 S + + + T GE G C P +S +S S Sbjct: 2573 SSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSS 2632 Query: 633 GRRKLTATEGPGSPRDAEDHSPSPNSS 659 +++ S + S S +SS Sbjct: 2633 SSSSSSSSSSSSSSSSSSSSSSSSSSS 2659 Score = 30.8 bits (68), Expect = 4.2 Identities = 37/142 (26%), Positives = 52/142 (36%), Gaps = 30/142 (21%) Query: 443 DLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPE 502 ++ E G RG + AG TA P G L R P L+ G GT Sbjct: 945 EMEEKGSKRGLEAAGKAG---------LATAGP------GLLPRKPPGLAAGPAGT---- 985 Query: 503 QEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRP-------LPPPHPQPPPHPQPPDLD 555 +A +P P P +L + + ED +P P HP PP PP Sbjct: 986 YGKAVSP--PPSPRASPVAALKAKVIQKLEDVSKPPAYAYPATPSSHPTSPPPASPPPTP 1043 Query: 556 G--HPEPSKAEVLRPESDELDE 575 G E + V+ + EL++ Sbjct: 1044 GITRKEEAPENVVEKKDLELEK 1065 Score = 30.0 bits (66), Expect = 7.1 Identities = 47/204 (23%), Positives = 65/204 (31%), Gaps = 31/204 (15%) Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKV 286 PG + CP+ PPP P + P PA F R + AP P V Sbjct: 326 PGPRPCPSPL-----PPPPAPPKGPPAPPAATPAGVYTVFREQGREHRVV--APTFVPSV 378 Query: 287 DRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGM 346 + P+ A+ D R ++ +A + P G P L Sbjct: 379 EAF------------DERPGPIQIASQARDARAREREAGRPGVLQAPP---GSPRPLDRP 423 Query: 347 QDLRLEGALHLLLAQ----QQLRARARAGSVRPRGQPTPGEML----PSLPVGSDSEGPE 398 + LR + ++ L + RA S PR E+L P GP Sbjct: 424 EGLREKNSVIRSLKRPPPADAPTVRATRASPDPRAYVPAKELLKPEADPRPCERAPRGPA 483 Query: 399 NEGTRAALAAAGLSGGRHTQPAGP 422 + A GL GR P GP Sbjct: 484 GPAAQQAAKLFGLEPGR-PPPTGP 506 >gi|146219832 myosin light chain kinase 3 [Homo sapiens] Length = 819 Score = 55.8 bits (133), Expect = 1e-07 Identities = 89/384 (23%), Positives = 130/384 (33%), Gaps = 25/384 (6%) Query: 275 MTHEAPKLSPKVDRLC--LLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEE 332 + H ++ K+ +C + + LH +P P A P + D +A W E Sbjct: 39 LLHFQEDVTEKLQSMCRDMGHLERGLHRLEASRAP-GPGGADGVPHI-DTQA----GWPE 92 Query: 333 PTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGS 392 EL+ A RLE ++ A RA A G+ + + M +P Sbjct: 93 VLELVRAMQQDAAQHGARLEALFRMVAAVD--RAIALVGATFQKSKVADFLMQGRVPWRR 150 Query: 393 DSEGPENEGTRAALAAAG-------LSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLS 445 S G E + + G + G + PG + P+ S Sbjct: 151 GSPGDSPEENKERVEEEGGKPKHVLSTSGVQSDAREPGEESQKADVLEGTAERLPPIRAS 210 Query: 446 EWGRARGQDTPKPAGQHGSLSPAAA---HTASPEPPTQSGPLTRSPQALSNGTKGTRVPE 502 G Q P G PA A H P P T S + L G + P Sbjct: 211 GLGADPAQAVVSPGQGDGVPGPAQAFPGHLPLPTKVEAKAPETPS-ENLRTGLELAPAPG 269 Query: 503 QEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSK 562 + +P P G S S P E+ R P P PQ P P P S Sbjct: 270 RVNVVSPSLEVAPGAGQGASSSRPDPEPLEEGTRLTPGPGPQCPGPPGLP-AQARATHSG 328 Query: 563 AEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEP 622 E S + E DTPG E+ ++ + + T E P Q QGPP + P Sbjct: 329 GETPPRISIHIQEMDTPG-EMLMTGRGSLGPTLTTEAPAA--AQPGKQGPPGTGRCLQAP 385 Query: 623 GDKASKKPSRGRRKLTATEGPGSP 646 G + ++ G R+L+ + SP Sbjct: 386 GTEPGEQTPEGARELSPLQESSSP 409 >gi|169658367 BAH domain and coiled-coil containing 1 [Homo sapiens] Length = 2608 Score = 55.5 bits (132), Expect = 2e-07 Identities = 125/541 (23%), Positives = 192/541 (35%), Gaps = 100/541 (18%) Query: 130 DRPKPRAKEGTSDPPSPLLLP----SPGGWKAITEKPPGGHEEAEEDHQG-VGLRGEEKP 184 +R + ++G S S +L SPG + E+P +E EED G + E+ Sbjct: 1184 ERSREEGEQGPSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEEDELGQQSMEDSEED 1243 Query: 185 AGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPP 244 G GA P++ P + + + TI + S + P + PA PP Sbjct: 1244 CG-----------GA--PDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPP 1290 Query: 245 ---PLPARSSPPSPAYERGLS-LDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300 PLP S A L+ L + S + E L+ + L L SL Sbjct: 1291 STVPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFNLQHLATLATAWSLVE 1350 Query: 301 QSPHSSPLAPAAAPS---------DPRLQDLKARE-------------AEAWEEPTELLG 338 + S APA P+ PR+Q L+ ++ A T+ +G Sbjct: 1351 AAGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDTQEVG 1410 Query: 339 LPSALAGMQDLRLEGALHLLLAQ--------QQLRARARAGSVRPRGQPTPGEMLPSLPV 390 + LA +Q E L Q + R+ AR G RPR + + P Sbjct: 1411 MRVRLAELQRRYKEKQRELARLQRKHDHERDESSRSPARRGPGRPRKRKHSSSLPAPRPT 1470 Query: 391 G----SDSEGPENEGTRAALAAAGLSGGRHTQPAGP-GRAQRTEAAATQDCALDKPLDLS 445 G SD + + T L A L GG +PA + +R+ A Q +++K Sbjct: 1471 GPLPRSDGKKVKAVRTSLGLLCAELRGGSGGEPAKKRSKLERSVYAGLQTASVEKA---- 1526 Query: 446 EWGRARGQDTPKPAGQHGSLSPAAAH-TASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504 K + G L+P+ AH A +P +S L P LS+ Q+ Sbjct: 1527 ---------QCKKSSCQGGLAPSVAHRVAQLKPKVKSKGL---PTGLSS--------FQQ 1566 Query: 505 EASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPH--PQPPDLDGHPEPSK 562 + +TP R S G+T HPQP H + P P + Sbjct: 1567 KEATPGGRIREKLSRAKSAKVSGATR-----------HPQPKGHGSRETPRCPAQPSVAA 1615 Query: 563 AEVLRPESDELD-----ETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK 617 ++ D D T+ P E GL A+ + G P + E Q +K++ Sbjct: 1616 SQEAGNGYDSEDCEGLLGTEAPPREAGLLLHTGASVAVLGPSPSSVVKMEANQKAKKKKE 1675 Query: 618 R 618 R Sbjct: 1676 R 1676 Score = 45.4 bits (106), Expect = 2e-04 Identities = 129/557 (23%), Positives = 183/557 (32%), Gaps = 91/557 (16%) Query: 161 KPPGGHEEAEEDHQGVGLRGEEKP------AGHRTSPVA---KISPGATLPESRAPDMSP 211 KP H + EE Q + KP A SP A K+ P P+ + P SP Sbjct: 947 KPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHPPDPKPPASSP 1006 Query: 212 Q---RISNQLHGTIAVVR---PGSQACPADRGPANGTPPPLPARSSPPS--PAYER---- 259 R S + PGS+ A+ G +S P P Y R Sbjct: 1007 TPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDLPPGYLRPMAG 1066 Query: 260 -GLSLDSFLRASR---PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPS 315 G SL S + +S P M AP P+ R L P +S L A + Sbjct: 1067 LGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEEPGLLSGAREA 1126 Query: 316 DPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRP 375 QDL A P PS L G+Q+L+ L + +A + G R Sbjct: 1127 T---QDLAATPYPTERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAHSTQGGARE 1183 Query: 376 RGQPTPGEMLPSLPVGSDSEGPENE-GTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQ 434 GE PS G+ S+ E G+ AL G QPA P + E Q Sbjct: 1184 ERSREEGEQGPS--SGASSQVLEQRAGSPGALEDEG------EQPA-PEEDELEEDELGQ 1234 Query: 435 DCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTA--------SPEPPTQSGPLTR 486 D D G P+ +L A + P+PP SGP + Sbjct: 1235 QSMEDSEEDCG--GAPDNSHPPRALPGLDALVAATINLGDLPSDSPPDPQPPAASGPPST 1292 Query: 487 SPQALSNGTKG------------------TRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528 P S+G G VPE+EE + + L + S + Sbjct: 1293 VPLPHSSGIHGIALLSELADLAIQRQRSERTVPEEEEDVLAFN-LQHLATLATAWSLVEA 1351 Query: 529 TEDEDTGRPLPPPHPQPPPHPQ-PPDLD----GHPEPSKAEVLRPESDELDETDTPGSEV 583 + + P PP P P+ P + K + + P +D DT EV Sbjct: 1352 AGLDSSTAPAQPPTANPCSGPRLTPRMQILQRKDTWTPKTKPVCPLKAAIDRLDT--QEV 1409 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643 G+ + +E + R +++ D++S+ P+R GP Sbjct: 1410 GMRVRLAELQRR---------YKEKQRELARLQRKHDHERDESSRSPAR--------RGP 1452 Query: 644 GSPRDAEDHSPSPNSSP 660 G PR + S P P Sbjct: 1453 GRPRKRKHSSSLPAPRP 1469 Score = 44.7 bits (104), Expect = 3e-04 Identities = 77/298 (25%), Positives = 104/298 (34%), Gaps = 65/298 (21%) Query: 426 QRTEAAATQDCALDKPLDLSEWGRARG-QDTPKPAG----QHGSLSPAAAHTASPE---- 476 Q+ AA Q D+ LDL E + + + T KP G+ SPAA T P Sbjct: 937 QQQRAAQFQRKPEDQHLDLEEPAQEKAPKSTHKPVALTPTAPGAPSPAAGPTKLPPCCHP 996 Query: 477 ------------PPTQSGPLTRSPQALSNGTKGTRVPEQEEAS----------------T 508 PP S P T + S+ G+RV EE + Sbjct: 997 PDPKPPASSPTPPPRPSAPCTLNVCPASSPGPGSRVRSAEEKNGEGQQSTADIITSEPDL 1056 Query: 509 PMDPSRPLPGSQLSLSS---PGSTEDEDTGRPLPP-PHPQP-----PPHPQPPDLDGHPE 559 P RP+ G SL S + ED +T + P P+P P P P E Sbjct: 1057 PPGYLRPMAGLGFSLPSDVHSSNLEDPETMQTTAPGAQPEPTRTFLPGEPPPCSPRSLEE 1116 Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTG------------EGPECICTQE 607 P R + +L T P +E G +A + G GPE Sbjct: 1117 PGLLSGAREATQDLAATPYP-TERGPQGKAADPSPLEGLQELQCAALLEAGGPEATGQAH 1175 Query: 608 HGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRDAED--HSPSPNSSPWEE 663 QG R+ +R+ E G++ PS G + GSP ED P+P EE Sbjct: 1176 STQGGARE-ERSREEGEQG---PSSGASSQVLEQRAGSPGALEDEGEQPAPEEDELEE 1229 Score = 32.0 bits (71), Expect = 1.9 Identities = 33/114 (28%), Positives = 42/114 (36%), Gaps = 7/114 (6%) Query: 167 EEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVR 226 E H+ PAG P A PG P S P M+ S++L G+ Sbjct: 15 ERGSLGHRSAAAAARLAPAGPAAQPPAHFQPGKYFP-SPLP-MASHTASSRLMGSSPASS 72 Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAP 280 + G A T P P+ SSPP AY S + S +HEAP Sbjct: 73 FMGSFLTSSLGSAASTHPSGPS-SSPPEQAYRGSHPTTSQIWFSH----SHEAP 121 >gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens] Length = 2524 Score = 55.1 bits (131), Expect = 2e-07 Identities = 49/205 (23%), Positives = 78/205 (38%), Gaps = 18/205 (8%) Query: 450 ARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTP 509 A G + P+ G S A T + T+S P + A G G + P A P Sbjct: 726 ASGNEVPR-----GECSGPA--TVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGP 778 Query: 510 MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPE 569 P + + + E TG P PP P PP PP + E + P Sbjct: 779 PPGPPTPPPEDIPAPTEPTPASEATGAPTPP--PAPPSPSAPPPVVPKEEKEEETAAAPP 836 Query: 570 SDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPR----KRKRASEPGDK 625 +E +E P +E + T E + CT+E +GP + + A+ G Sbjct: 837 VEEGEEQKPPAAE-----ELAVDTGKAEEPVKSECTEEAEEGPAKGKDAEAAEATAEGAL 891 Query: 626 ASKKPSRGRRKLTATEGPGSPRDAE 650 ++K G + T + G+P+D++ Sbjct: 892 KAEKKEGGSGRATTAKSSGAPQDSD 916 Score = 43.1 bits (100), Expect = 8e-04 Identities = 107/471 (22%), Positives = 149/471 (31%), Gaps = 101/471 (21%) Query: 107 EMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGH 166 E +G+ E + EE + L G+ PR G P+ + S TE P H Sbjct: 706 EASGVSGNEEEMVEEAEALHASGNEV-PR---GECSGPATVNNSSD------TESIPSPH 755 Query: 167 EEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVR 226 EA +D G G + PA + GA P P P+ I T Sbjct: 756 TEAAKD---TGQNGPKPPA----------TLGADGPPPGPPTPPPEDIPAPTEPT----- 797 Query: 227 PGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKV 286 PA TPPP P S P P + + A+ P E K P Sbjct: 798 ------PASEATGAPTPPPAPPSPSAPPPVVPKEEKEEE--TAAAPPVEEGEEQK-PPAA 848 Query: 287 DRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGM 346 + L + + P S A + +D +A EA A Sbjct: 849 EELAVDTG----KAEEPVKSECTEEAEEGPAKGKDAEAAEATA----------------- 887 Query: 347 QDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAAL 406 EGAL A+++ RA + + G P + + E + R Sbjct: 888 -----EGALK---AEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLS 939 Query: 407 AAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLS 466 L P G RA + + KPLDL + + P H Sbjct: 940 PRPSL-----LTPTGDPRA---------NASPQKPLDLKQLKQRAAAIPPIVTKVHEPPR 985 Query: 467 PAAAHT----ASPEPPTQSGPLTRSPQALSNGTKG----TRVPEQEEASTPM-DPSRPLP 517 AA T +P PP P + +PQ + +G P +EA P+ P+ Sbjct: 986 EDAAPTKPAPPAPPPPQNLQPESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAFAAE 1045 Query: 518 GSQLSLSSPGSTEDEDTGRPLP-PPHPQPPPHPQPPDLD-------GHPEP 560 +L PG +G P P PP P PD GHP P Sbjct: 1046 AQKL----PGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLP 1092 Score = 33.9 bits (76), Expect = 0.49 Identities = 135/656 (20%), Positives = 214/656 (32%), Gaps = 188/656 (28%) Query: 28 ELNSERCRDAQRIEELFS-----KNHQLREQQKTLKENLRVLENRLRAGLCDRCMVTQEL 82 E NSE Q+ EL S + E+ +T K+ L LE+ R + ++ + Sbjct: 589 EANSEEAITPQQSAELASMELNESSRWTEEEMETAKKGL--LEHGRNWSAIARMVGSKTV 646 Query: 83 ARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEGTSD 142 ++ + F QNL I + + LK E E K+ + A E + Sbjct: 647 SQCKNFYFNYKKRQNLDEIL----QQHKLKMEKERNARRKKK------KAPAAASEEAAF 696 Query: 143 PPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLP 202 PP + G EE E+ + + G E P G + P AT+ Sbjct: 697 PPVV------EDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGP-------ATV- 742 Query: 203 ESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPP--LPARSSPPSPAYERG 260 N T ++ P ++A D G NG PP L A PP P Sbjct: 743 -------------NNSSDTESIPSPHTEAAK-DTGQ-NGPKPPATLGADGPPPGP----- 782 Query: 261 LSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQ 320 P+ + P + P S +P + P AP + + P + Sbjct: 783 -----------PTPPPEDIPAPTEPT--------PASEATGAP-TPPPAPPSPSAPPPVV 822 Query: 321 DLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPT 380 + +E E P G ++L ++ + + A G + Sbjct: 823 PKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPAK------ 876 Query: 381 PGEMLPSLPVGSDSEGPENEGTRAALAAAGLSG-GRHTQPAGPGRAQRTEAAATQDCALD 439 G D+E E A A G GR T G Q ++++AT C+ D Sbjct: 877 ----------GKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSAT--CSAD 924 Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499 + +D +E G +P+P+ + P A ASP+ P L + A+ Sbjct: 925 E-VDEAEGGDKNRLLSPRPSLLTPTGDPRA--NASPQKPLDLKQLKQRAAAIPPIVTKVH 981 Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE 559 P +E+A+ P++P P P P PP + QP Sbjct: 982 EPPREDAA----PTKPAP-----------------------PAPPPPQNLQP-------- 1006 Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA 619 E+D P Q+ G P K + Sbjct: 1007 ---------------ESDAP--------------------------QQPGSSPRGKSRSP 1025 Query: 620 SEPGDKASKKP------SRGRRKLTA-----TEG---PGSPRD---AEDHSPSPNS 658 + P DK ++KP + +KL T G P PR+ A H+P P++ Sbjct: 1026 APPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSA 1081 >gi|226509740 SR-related CTD-associated factor 1 [Homo sapiens] Length = 1312 Score = 54.7 bits (130), Expect = 3e-07 Identities = 100/434 (23%), Positives = 156/434 (35%), Gaps = 77/434 (17%) Query: 233 PADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLL 292 P+ P+ PPP PA +PP+P ++ P T EA P ++ Sbjct: 201 PSSSSPSPPPPPPPPAPPAPPAPRFD----------IYDPFHPTDEAYSPPPAPEQKYDP 250 Query: 293 NRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLE 352 P S+P + A PS ++ + E E E+ E GL +++ + + L Sbjct: 251 FEPTG-------SNPSSSAGTPSPEEEEEEEEEEEEEEEDEEEEEGLSQSISRISE-TLA 302 Query: 353 GALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRA--ALAAAG 410 G Q S RP QPT P P P+ + TRA A+ Sbjct: 303 GIYDDNSLSQDFPGDE---SPRPDAQPTQPTPAPGTP-------PQVDSTRADGAMRRRV 352 Query: 411 LSGGRHTQPAGPGRAQRTEAAATQDCALDKPL------DLSEWGRARGQDTP-------K 457 G + G+ E AL PL ++ E + ++ P + Sbjct: 353 FVVGTEAEACREGKVS-VEVVTAGGAALPPPLLPPGDSEIEEGEIVQPEEEPRLALSLFR 411 Query: 458 PAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQ--------ALSNGTKGTRVPEQEEASTP 509 P G+ +PAA+ T + +P Q P R+P+ A S+G +V E A P Sbjct: 412 PGGRAARPTPAASATPTAQPLPQP-PAPRAPEGDDFLSLHAESDGEGALQVDLGEPAPAP 470 Query: 510 MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPE 569 P+ L L T+ + R P P P P P G P K+ R Sbjct: 471 --PAADSRWGGLDLRRKILTQRRERYR---QRSPSPAPAPAPAAAAGPPTRKKSRRERKR 525 Query: 570 SDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKAS-- 627 S E + +A +++S T P + + + R R +PG AS Sbjct: 526 SGE-------------AKEAASSSSGTQPAPPAPASPWDSK---KHRSRDRKPGSHASSS 569 Query: 628 -KKPSRGRRKLTAT 640 ++ SR R + +T Sbjct: 570 ARRRSRSRSRSRST 583 Score = 36.2 bits (82), Expect = 0.100 Identities = 44/184 (23%), Positives = 67/184 (36%), Gaps = 16/184 (8%) Query: 485 TRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ 544 T SPQ SN ++ T + P+ P P + SSP + + P PPP P Sbjct: 159 TVSPQ--SNSSRPTCARHLTLGTGDGGPAPP-PAPSSASSSPSPSPSSSSPSPPPPPPPP 215 Query: 545 PPPHPQPPDLDGHP--EPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPEC 602 PP P P D + P+ P + E + P G + + A T + E Sbjct: 216 APPAPPAPRFDIYDPFHPTDEAYSPPPAPE--QKYDPFEPTGSNPSSSAGTPSPEE---- 269 Query: 603 ICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRD--AEDHSPSPNSSP 660 +E + + + E + S+ SR L S D SP P++ P Sbjct: 270 ---EEEEEEEEEEEEEDEEEEEGLSQSISRISETLAGIYDDNSLSQDFPGDESPRPDAQP 326 Query: 661 WEET 664 + T Sbjct: 327 TQPT 330 Score = 34.7 bits (78), Expect = 0.29 Identities = 37/152 (24%), Positives = 49/152 (32%), Gaps = 33/152 (21%) Query: 448 GRARGQDTPKPAGQHGSLSPA-AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEA 506 G G P PA S SP+ + ++SP PP P Sbjct: 178 GTGDGGPAPPPAPSSASSSPSPSPSSSSPSPPPPPPP----------------------- 214 Query: 507 STPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHP---QPPDLDGHPEPSKA 563 P P+ P P + + P DE P P P P P G P P + Sbjct: 215 --PAPPAPPAP--RFDIYDPFHPTDEAYSPPPAPEQKYDPFEPTGSNPSSSAGTPSPEEE 270 Query: 564 EVLRPESDELDETDTPGSEVGLSSQAEATTST 595 E E +E +E + E GLS + T Sbjct: 271 E--EEEEEEEEEEEDEEEEEGLSQSISRISET 300 Score = 31.2 bits (69), Expect = 3.2 Identities = 99/457 (21%), Positives = 153/457 (33%), Gaps = 71/457 (15%) Query: 247 PARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDR-LCLLNRPLSLHLQSPHS 305 PA + PPS + G DS R + P P + D L + R +++ + S Sbjct: 663 PAPAPPPSGSTSCG-DRDSRRRGAVP-------PSIQDLTDHDLFAIKRTITVG-RLDKS 713 Query: 306 SPLAPAAAP-SDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQL 364 P P+ AP S P+ + L E + EE + +D R GA + ++ Sbjct: 714 DPRGPSPAPASSPKREVLYDSEGLSGEER-------GGKSSQKDRRRSGAASSSSSSREK 766 Query: 365 RARARA--GSVRPRGQPT-------------PGEMLPSLPVGSDSEGPENEGTRAALAAA 409 +R +A G R R + P E PS G + P + G+ ++ +++ Sbjct: 767 GSRRKALDGGDRDRDRDRDRDRDRSSKKARPPKESAPSS--GPPPKPPVSSGSGSSSSSS 824 Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGR--ARGQDTPKPAGQHGSLSP 467 S + + R ++T L G +R +++ P + +P Sbjct: 825 SCSSRKVKLQSKVAVLIREGVSSTTPAKDAASAGLGSIGVKFSRDRESRSPFLKPDERAP 884 Query: 468 AAAHTASP--EPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLS- 524 A+P P ++ ++ + GTKG P + G Q+SL Sbjct: 885 TEMAKAAPGSTKPKKTKVKAKAGAKKTKGTKGKTKPSKTRKKVRSGGGSGGSGGQVSLKK 944 Query: 525 -----------SPGSTEDEDTGRP-------LPPPHPQPPPHPQPPDLDGHPEPSKAEVL 566 + G+ E +G PPP PPP PD K Sbjct: 945 SKADSCSQAAGTKGAEETSWSGEERAAKVPSTPPPKAAPPPPALTPDSQTVDSSCKT--- 1001 Query: 567 RPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKA 626 PE L E T E G+ AE E E +E + P S Sbjct: 1002 -PEVSFLPEEAT--EEAGVRGGAEEEEEEEEEEEE---EEEEEEQQPATTTATSTAAAAP 1055 Query: 627 SKKPSRGRR--KLTATEGPGSPRDAEDHSPSPNSSPW 661 S PS G A +GP S P P PW Sbjct: 1056 STAPSAGSTAGDSGAEDGPASRVSQLPTLPPP--MPW 1090 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 53.9 bits (128), Expect = 5e-07 Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 E+ + T + K S P S+ + G A+ P + PA+ Sbjct: 168 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 226 Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 TP P P A ++P PA S + + P+ AP +PK Sbjct: 227 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 285 Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353 P +S ++P PA P P K +EPT P+ E Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 340 Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409 A + A + PT P E P+ P + + P T++A Sbjct: 341 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 400 Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468 T+ A P + T++ A P + + + TPK PA Sbjct: 401 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 459 Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528 T P P T P +P+ + T P E P P +P P + L+ + Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 517 Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587 T +E T P P P P P P+ P P+ + P + + TP Sbjct: 518 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 567 Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640 + T TT +G +E P+K EP KP+ K TA Sbjct: 568 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625 Query: 641 EGPGSPRDAEDHSPSPNS 658 P P P+P + Sbjct: 626 TTPKEPAPTTPKEPAPTT 643 Score = 52.0 bits (123), Expect = 2e-06 Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%) Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 E + K+ +VL +P P+A+ T P L +P T K P E Sbjct: 180 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 234 Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229 + E P +++P P T + AP + + Sbjct: 235 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294 Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289 P + P T P PA ++P PA + P+ T E +PK Sbjct: 295 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 350 Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348 +P ++P PA P +P K +EP P+ Sbjct: 351 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 398 Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408 E A + + + TP E P+ P P+ Sbjct: 399 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 458 Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465 A + + T P P E A T K L + + KPA L Sbjct: 459 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 514 Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523 +P +P P + P T P+A + T P + P P P P + + + Sbjct: 515 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 572 Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583 ++P T P P +P P P P + + P + + TP Sbjct: 573 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 632 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636 + + A T+ G P + +E P+K P S KP+ K Sbjct: 633 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 690 Query: 637 LTATEGPGSPRDAEDHSPSPNS 658 TA P P P+P + Sbjct: 691 ETAPTTPKEPAPTTPKKPAPTT 712 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%) Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444 PSLP SD S+ + + + Q + G+ + T A TQ DL Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187 Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504 + + + TPK + + PA P P T P + +P+ + T Sbjct: 188 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 237 Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561 S P P P P + S ++P T P P P P P +P P+ Sbjct: 238 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 296 Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 + P + + TP E ++ E T +T P E Sbjct: 297 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 339 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 P K+P+ K A P P P+P ++ Sbjct: 340 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 377 Score = 40.4 bits (93), Expect = 0.005 Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%) Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249 SP P T P+ AP +P++ + A P A + PA TP PA Sbjct: 419 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 476 Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305 ++P A + P +T P KL+P P L +P Sbjct: 477 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524 Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358 +P P AAAP+ P+ + A P E P+ +G Sbjct: 525 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 582 Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418 L + P+ +P P E+ P+ S + A + + Sbjct: 583 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 632 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476 P P T T L +P + A + P G + S A T E Sbjct: 633 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 692 Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535 P T P +P+ + T T P E STP P + SP + E + Sbjct: 693 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 748 Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592 P P P P P P +K E+ D+ E D TP + + T Sbjct: 749 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 807 Query: 593 TSTTGEGPE 601 +TT + E Sbjct: 808 ATTTEKTTE 816 Score = 33.1 bits (74), Expect = 0.84 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%) Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508 T KP SL P + + T + E ++ T + + S K +E S Sbjct: 120 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 179 Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567 ++ L + L+ P + T P L P P P+ P EP+ + Sbjct: 180 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 239 Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619 + + T + + A T+T T + P T+E P K A Sbjct: 240 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 296 Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658 EP KKP+ K A P P P+P + Sbjct: 297 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 337 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 53.9 bits (128), Expect = 5e-07 Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 E+ + T + K S P S+ + G A+ P + PA+ Sbjct: 209 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 267 Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 TP P P A ++P PA S + + P+ AP +PK Sbjct: 268 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 326 Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353 P +S ++P PA P P K +EPT P+ E Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 381 Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409 A + A + PT P E P+ P + + P T++A Sbjct: 382 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 441 Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468 T+ A P + T++ A P + + + TPK PA Sbjct: 442 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 500 Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528 T P P T P +P+ + T P E P P +P P + L+ + Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 558 Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587 T +E T P P P P P P+ P P+ + P + + TP Sbjct: 559 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 608 Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640 + T TT +G +E P+K EP KP+ K TA Sbjct: 609 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666 Query: 641 EGPGSPRDAEDHSPSPNS 658 P P P+P + Sbjct: 667 TTPKEPAPTTPKEPAPTT 684 Score = 52.0 bits (123), Expect = 2e-06 Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%) Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 E + K+ +VL +P P+A+ T P L +P T K P E Sbjct: 221 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 275 Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229 + E P +++P P T + AP + + Sbjct: 276 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335 Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289 P + P T P PA ++P PA + P+ T E +PK Sbjct: 336 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 391 Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348 +P ++P PA P +P K +EP P+ Sbjct: 392 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 439 Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408 E A + + + TP E P+ P P+ Sbjct: 440 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 499 Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465 A + + T P P E A T K L + + KPA L Sbjct: 500 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 555 Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523 +P +P P + P T P+A + T P + P P P P + + + Sbjct: 556 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 613 Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583 ++P T P P +P P P P + + P + + TP Sbjct: 614 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 673 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636 + + A T+ G P + +E P+K P S KP+ K Sbjct: 674 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 731 Query: 637 LTATEGPGSPRDAEDHSPSPNS 658 TA P P P+P + Sbjct: 732 ETAPTTPKEPAPTTPKKPAPTT 753 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%) Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444 PSLP SD S+ + + + Q + G+ + T A TQ DL Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228 Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504 + + + TPK + + PA P P T P + +P+ + T Sbjct: 229 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 278 Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561 S P P P P + S ++P T P P P P P +P P+ Sbjct: 279 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 337 Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 + P + + TP E ++ E T +T P E Sbjct: 338 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 380 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 P K+P+ K A P P P+P ++ Sbjct: 381 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 418 Score = 40.4 bits (93), Expect = 0.005 Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%) Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249 SP P T P+ AP +P++ + A P A + PA TP PA Sbjct: 460 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 517 Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305 ++P A + P +T P KL+P P L +P Sbjct: 518 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565 Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358 +P P AAAP+ P+ + A P E P+ +G Sbjct: 566 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 623 Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418 L + P+ +P P E+ P+ S + A + + Sbjct: 624 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 673 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476 P P T T L +P + A + P G + S A T E Sbjct: 674 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 733 Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535 P T P +P+ + T T P E STP P + SP + E + Sbjct: 734 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 789 Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592 P P P P P P +K E+ D+ E D TP + + T Sbjct: 790 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 848 Query: 593 TSTTGEGPE 601 +TT + E Sbjct: 849 ATTTEKTTE 857 Score = 33.1 bits (74), Expect = 0.84 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%) Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508 T KP SL P + + T + E ++ T + + S K +E S Sbjct: 161 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 220 Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567 ++ L + L+ P + T P L P P P+ P EP+ + Sbjct: 221 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 280 Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619 + + T + + A T+T T + P T+E P K A Sbjct: 281 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 337 Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658 EP KKP+ K A P P P+P + Sbjct: 338 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 378 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 53.9 bits (128), Expect = 5e-07 Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 E+ + T + K S P S+ + G A+ P + PA+ Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 319 Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 TP P P A ++P PA S + + P+ AP +PK Sbjct: 320 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 378 Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353 P +S ++P PA P P K +EPT P+ E Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 433 Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409 A + A + PT P E P+ P + + P T++A Sbjct: 434 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 493 Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468 T+ A P + T++ A P + + + TPK PA Sbjct: 494 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 552 Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528 T P P T P +P+ + T P E P P +P P + L+ + Sbjct: 553 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 610 Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587 T +E T P P P P P P+ P P+ + P + + TP Sbjct: 611 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 660 Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640 + T TT +G +E P+K EP KP+ K TA Sbjct: 661 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718 Query: 641 EGPGSPRDAEDHSPSPNS 658 P P P+P + Sbjct: 719 TTPKEPAPTTPKEPAPTT 736 Score = 52.0 bits (123), Expect = 2e-06 Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%) Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 E + K+ +VL +P P+A+ T P L +P T K P E Sbjct: 273 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 327 Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229 + E P +++P P T + AP + + Sbjct: 328 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387 Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289 P + P T P PA ++P PA + P+ T E +PK Sbjct: 388 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 443 Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348 +P ++P PA P +P K +EP P+ Sbjct: 444 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 491 Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408 E A + + + TP E P+ P P+ Sbjct: 492 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 551 Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465 A + + T P P E A T K L + + KPA L Sbjct: 552 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 607 Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523 +P +P P + P T P+A + T P + P P P P + + + Sbjct: 608 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 665 Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583 ++P T P P +P P P P + + P + + TP Sbjct: 666 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 725 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636 + + A T+ G P + +E P+K P S KP+ K Sbjct: 726 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 783 Query: 637 LTATEGPGSPRDAEDHSPSPNS 658 TA P P P+P + Sbjct: 784 ETAPTTPKEPAPTTPKKPAPTT 805 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%) Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444 PSLP SD S+ + + + Q + G+ + T A TQ DL Sbjct: 221 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 280 Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504 + + + TPK + + PA P P T P + +P+ + T Sbjct: 281 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 330 Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561 S P P P P + S ++P T P P P P P +P P+ Sbjct: 331 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 389 Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 + P + + TP E ++ E T +T P E Sbjct: 390 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 432 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 P K+P+ K A P P P+P ++ Sbjct: 433 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 470 Score = 40.4 bits (93), Expect = 0.005 Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%) Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249 SP P T P+ AP +P++ + A P A + PA TP PA Sbjct: 512 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 569 Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305 ++P A + P +T P KL+P P L +P Sbjct: 570 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617 Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358 +P P AAAP+ P+ + A P E P+ +G Sbjct: 618 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 675 Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418 L + P+ +P P E+ P+ S + A + + Sbjct: 676 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 725 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476 P P T T L +P + A + P G + S A T E Sbjct: 726 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 785 Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535 P T P +P+ + T T P E STP P + SP + E + Sbjct: 786 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 841 Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592 P P P P P P +K E+ D+ E D TP + + T Sbjct: 842 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 900 Query: 593 TSTTGEGPE 601 +TT + E Sbjct: 901 ATTTEKTTE 909 Score = 33.1 bits (74), Expect = 0.84 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%) Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508 T KP SL P + + T + E ++ T + + S K +E S Sbjct: 213 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 272 Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567 ++ L + L+ P + T P L P P P+ P EP+ + Sbjct: 273 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 332 Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619 + + T + + A T+T T + P T+E P K A Sbjct: 333 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 389 Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658 EP KKP+ K A P P P+P + Sbjct: 390 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 430 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 53.9 bits (128), Expect = 5e-07 Identities = 106/498 (21%), Positives = 159/498 (31%), Gaps = 42/498 (8%) Query: 181 EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 E+ + T + K S P S+ + G A+ P + PA+ Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPAS 360 Query: 241 GTPP-PLP-----ARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 TP P P A ++P PA S + + P+ AP +PK Sbjct: 361 TTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT-TPKEPAPTTTKE 419 Query: 295 PLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353 P +S ++P PA P P K +EPT P+ E Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT-----PTTPKEPAPTTKEP 474 Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPT-PGEMLPSL---PVGSDSEGPENEGTRAALAAA 409 A + A + PT P E P+ P + + P T++A Sbjct: 475 APTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTT 534 Query: 410 GLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR-GQDTPKPAGQHGSLSPA 468 T+ A P + T++ A P + + + TPK PA Sbjct: 535 KEPAPTTTKSA-PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPA 593 Query: 469 AAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGS 528 T P P T P +P+ + T P E P P +P P + L+ + Sbjct: 594 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP--T 651 Query: 529 TEDEDTGRPLPPPHPQP-PPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSS 587 T +E T P P P P P P+ P P+ + P + + TP Sbjct: 652 TPEEPT--PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTP-------- 701 Query: 588 QAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRKLTAT 640 + T TT +G +E P+K EP KP+ K TA Sbjct: 702 --KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759 Query: 641 EGPGSPRDAEDHSPSPNS 658 P P P+P + Sbjct: 760 TTPKEPAPTTPKEPAPTT 777 Score = 52.0 bits (123), Expect = 2e-06 Identities = 109/562 (19%), Positives = 169/562 (30%), Gaps = 46/562 (8%) Query: 114 ENETLKEEVKRLRVLGDRPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173 E + K+ +VL +P P+A+ T P L +P T K P E Sbjct: 314 EKTSAKDLAPTSKVLA-KPTPKAETTTKGPA----LTTPKEPTPTTPKEPASTTPKEPTP 368 Query: 174 QGVGLRG----EEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS 229 + E P +++P P T + AP + + Sbjct: 369 TTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428 Query: 230 QACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRL 289 P + P T P PA ++P PA + P+ T E +PK Sbjct: 429 PTTPKEPAP---TTPKKPAPTTPKEPAPTTPKE-PTPTTPKEPAPTTKEPAPTTPKEPAP 484 Query: 290 CLLNRPLSLHLQSPHSSPLAPA-AAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348 +P ++P PA P +P K +EP P+ Sbjct: 485 TAPKKPAP-------TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPA-----PTTTKSAPT 532 Query: 349 LRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAA 408 E A + + + TP E P+ P P+ Sbjct: 533 TTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEP 592 Query: 409 AGLSGGRH--TQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS-L 465 A + + T P P E A T K L + + KPA L Sbjct: 593 APTTTKKPAPTTPKEPAPTTPKETAPTTP----KKLTPTTPEKLAPTTPEKPAPTTPEEL 648 Query: 466 SPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGS--QLSL 523 +P +P P + P T P+A + T P + P P P P + + + Sbjct: 649 APTTPEEPTPTTPEEPAPTT--PKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAP 706 Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583 ++P T P P +P P P P + + P + + TP Sbjct: 707 TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPA 766 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRK-------RKRASEPGDKASKKPSRGRRK 636 + + A T+ G P + +E P+K P S KP+ K Sbjct: 767 PTTPKEPAPTTPKGTAPTTL--KEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPK 824 Query: 637 LTATEGPGSPRDAEDHSPSPNS 658 TA P P P+P + Sbjct: 825 ETAPTTPKEPAPTTPKKPAPTT 846 Score = 45.8 bits (107), Expect = 1e-04 Identities = 59/278 (21%), Positives = 91/278 (32%), Gaps = 32/278 (11%) Query: 386 PSLPVGSD-SEGPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDL 444 PSLP SD S+ + + + Q + G+ + T A TQ DL Sbjct: 262 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 321 Query: 445 SEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQE 504 + + + TPK + + PA P P T P + +P+ + T Sbjct: 322 APTSKVLAKPTPK--AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTI-------- 371 Query: 505 EASTPMDPSRPLPGSQLSL-SSPGSTEDEDTGRPLP--PPHPQPPPHPQPPDLDGHPEPS 561 S P P P P + S ++P T P P P P P +P P+ Sbjct: 372 -KSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPT 430 Query: 562 KAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 + P + + TP E ++ E T +T P E Sbjct: 431 TPKEPAPTTPKKPAPTTP-KEPAPTTPKEPTPTT----------------PKEPAPTTKE 473 Query: 622 PGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSS 659 P K+P+ K A P P P+P ++ Sbjct: 474 PAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTT 511 Score = 40.4 bits (93), Expect = 0.005 Identities = 93/429 (21%), Positives = 136/429 (31%), Gaps = 48/429 (11%) Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPAR 249 SP P T P+ AP +P++ + A P A + PA TP PA Sbjct: 553 SPTTTKEPAPTTPKEPAPT-TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE-PAP 610 Query: 250 SSPPSPAYERGLSLDSFLRASRPSAMTHEAP-KLSPKVDRLCLLNRPLSLHLQSPHS--- 305 ++P A + P +T P KL+P P L +P Sbjct: 611 TTPKETA------------PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658 Query: 306 ------SPLAP-AAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLL 358 +P P AAAP+ P+ + A P E P+ +G Sbjct: 659 TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKE--PAPTTPKETAPTTPKGTAPTT 716 Query: 359 LAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQ 418 L + P+ +P P E+ P+ S + A + + Sbjct: 717 LKEP--------APTTPK-KPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-KEPA 766 Query: 419 PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPA-GQHGSLSPAAAHTASPE- 476 P P T T L +P + A + P G + S A T E Sbjct: 767 PTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKET 826 Query: 477 -PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTG 535 P T P +P+ + T T P E STP P + SP + E + Sbjct: 827 APTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHK----SPDESTPELSA 882 Query: 536 RPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETD---TPGSEVGLSSQAEAT 592 P P P P P P +K E+ D+ E D TP + + T Sbjct: 883 EPTPKALENSPKEPGVPTTK-TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKET 941 Query: 593 TSTTGEGPE 601 +TT + E Sbjct: 942 ATTTEKTTE 950 Score = 33.1 bits (74), Expect = 0.84 Identities = 47/221 (21%), Positives = 73/221 (33%), Gaps = 20/221 (9%) Query: 455 TPKPAGQHGSLSPAA------AHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEAST 508 T KP SL P + + T + E ++ T + + S K +E S Sbjct: 254 TAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSI 313 Query: 509 PMDPSRPLPGSQLSLSSPGSTEDEDTGRP-LPPPHPQPPPHPQPPDLDGHPEPSKAEVLR 567 ++ L + L+ P + T P L P P P+ P EP+ + Sbjct: 314 EKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKS 373 Query: 568 PESDELDETDTPGSEVGLSSQAEATTST------TGEGPECICTQEHGQGPPRKRKRA-- 619 + + T + + A T+T T + P T+E P K A Sbjct: 374 APTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPT 430 Query: 620 --SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNS 658 EP KKP+ K A P P P+P + Sbjct: 431 TPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTT 471 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 53.9 bits (128), Expect = 5e-07 Identities = 123/534 (23%), Positives = 164/534 (30%), Gaps = 74/534 (13%) Query: 163 PGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTI 222 PG E D V +G+ K GH TS K PG E++ Sbjct: 377 PGDTPTDEPDALYVACQGQPK-GGHVTSMQPK-EPGPLQCEAKP---------------- 418 Query: 223 AVVRPGSQACPADRGPANGTPPPLPA-RSSPPSPAYERGLSLDSFLRASRPSAMTHEAPK 281 + + G Q P P N P LP SP SP E P++ EA + Sbjct: 419 -LGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEES-----------PTSPPPEASR 466 Query: 282 LSPKVDRLCLLNRPLSLHLQSP-HSSPLAPAAAPSD----PRLQDLKAREAEAWEEPTEL 336 LSP + L P +LHL P SPL+P S P E P E Sbjct: 467 LSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEES 526 Query: 337 LGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEG 396 P+ + L + L P P + P S Sbjct: 527 PPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSP--PPEASRLSPPPEESPMSPP 584 Query: 397 PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTP 456 PE A+ L P P + + + L P + S + Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPM 644 Query: 457 KPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPL 516 P + LSP + PP +S PL+ P+ PE S P + S Sbjct: 645 SPPPEVSRLSPLPVVSRLSPPPEES-PLSPPPEESPTSPP----PEASRLSPPPEDSPTS 699 Query: 517 PGSQLSLSSPGSTEDEDTGRPLP---------PPHPQPPPHPQPPDLDGHPE-----PSK 562 P + SP S ED+ LP P PQ P + P L PE P Sbjct: 700 PPPE---DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRP 756 Query: 563 AEV-LRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASE 621 E L P+++E + P + E S EGP E P+ + Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816 Query: 622 PGDK---ASKKPSRGRRKLTATEGPGSPRDAEDH----------SPSPNSSPWE 662 P + S +P + E SPR E H SP P P E Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEE 870 Score = 46.6 bits (109), Expect = 7e-05 Identities = 104/436 (23%), Positives = 145/436 (33%), Gaps = 75/436 (17%) Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANG-- 241 P R SP + SP + PE P+ ++ + P + P P Sbjct: 621 PEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT 680 Query: 242 TPPPLPARSSPP------SPAYERGL-------SLDSFLRASRPSAMTHEAPKLSPKVDR 288 +PPP +R SPP SP E SL S P E P+L P+ + Sbjct: 681 SPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG 740 Query: 289 LCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQD 348 L RP + PH SP P +P L +A E +P E P A ++ Sbjct: 741 PHLSPRP-----EEPHLSP-----RPEEPHLSP-QAEEPHLSPQPEE----PCLCAVPEE 785 Query: 349 LRL----EGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRA 404 L EG HL ++L + + P P P E S P++E Sbjct: 786 PHLSPQAEGP-HLSPQPEELHLSPQ--TEEPHLSPVPEEPCLSPQPEESHLSPQSE--EP 840 Query: 405 ALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGS 464 L+ + P + R E + P +L + P S Sbjct: 841 CLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF----------PPPGEPS 890 Query: 465 LSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLS 524 LSP A EP PL+ P+ L G P P DP P ++ + Sbjct: 891 LSPLLGEPALSEPGEP--PLSPLPEELPLSPSGE--PSLSPQLMPPDPLPPPLSPIITAA 946 Query: 525 SP-------------GSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESD 571 +P G+ D D PL P + P P P PEP +L P Sbjct: 947 APPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP--- 1003 Query: 572 ELDETDTPGSEVGLSS 587 +PGS VG +S Sbjct: 1004 ------SPGSPVGPAS 1013 Score = 45.4 bits (106), Expect = 2e-04 Identities = 133/572 (23%), Positives = 207/572 (36%), Gaps = 110/572 (19%) Query: 22 LQNKLLELNSERCRDAQRIEEL--FSKNHQLREQQKTLKENLRVLENRLRAGLCDRCMVT 79 LQ L+ + + AQ + L + QL++QQ+ ++ + L+ + + + Sbjct: 3876 LQQSLMSHSGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQ-------LQQ 3928 Query: 80 QELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRLRVLGDRPKPRAKEG 139 Q+L +++QQ Q LQ+ + L+++ + L+++ ++ + + + + + G Sbjct: 3929 QQLQQQQQQ-------QQLQQ-----QQQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMG 3976 Query: 140 TSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPAGHRTSPVAKISPGA 199 + LL P ++ ++ +G KP H +SP A + P Sbjct: 3977 LLNQSRTLLSP----------------QQQQQQQVALGPGMPAKPLQHFSSPGA-LGPTL 4019 Query: 200 TLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTPPPLPARSSPPSPAYER 259 L + P S A GP+ PL ++P S A E Sbjct: 4020 LLTGKEQNTVDPAVSSE-----------------ATEGPSTHQGGPLAIGTTPESMATEP 4062 Query: 260 GLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHS-SPLAPAAAPSDPR 318 G S S S + P+ P+ L L PL L Q S L A S + Sbjct: 4063 GEVKPSL---SGDSQLLLVQPQPQPQPSSL-QLQPPLRLPGQQQQQVSLLHTAGGGSHGQ 4118 Query: 319 LQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQ 378 L + EA + LL PS G Q + +LL QQ + R + P+ Sbjct: 4119 LGSGSSSEASS---VPHLLAQPSVSLGDQPGSM--TQNLLGPQQPMLERPMQNNTGPQ-P 4172 Query: 379 PTPGEMLPSLPVGSDSEG----PENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQ 434 P PG +L S G G P RA L L+ + P + Q+ +A Q Sbjct: 4173 PKPGPVLQS---GQGLPGVGIMPTVGQLRAQLQGV-LAKNPQLRHLSPQQQQQLQALLMQ 4228 Query: 435 -----DCALDKPLDLSEWGRARGQDTPK-------------PAGQHGSLSPAAAHTASPE 476 A+ + E G Q +P P Q G L A Sbjct: 4229 RQLQQSQAVRQTPPYQEPGT---QTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG 4285 Query: 477 PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGR 536 PP P P ALS G V S+P +P RP SQL P + T Sbjct: 4286 PPRLPAP----PGALSTGPVLGPVHPTPPPSSPQEPKRP---SQL----PSPSSQLPTEA 4334 Query: 537 PLPPPHPQPPPHPQPPDLD---GHPEPSKAEV 565 LPP HP P PQ P L+ G P+ A++ Sbjct: 4335 QLPPTHP-GTPKPQGPTLEPPPGRVSPAAAQL 4365 Score = 43.5 bits (101), Expect = 6e-04 Identities = 111/479 (23%), Positives = 154/479 (32%), Gaps = 87/479 (18%) Query: 184 PAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPANGTP 243 P R S V SPG L P S H I RPGS P + P P Sbjct: 2330 PLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDI--FRPGSYTDPYAQPPLTPRP 2387 Query: 244 PPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSP 303 P P S P R L D F R P++ ++ SP L RPLS P Sbjct: 2388 QPPPPESCCALP--PRSLPSDPFSRV--PASPQSQSSSQSP------LTPRPLSAEAFCP 2437 Query: 304 HSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGAL-HLLLAQQ 362 SP+ P DP + ++ +P L P + G+L H L Sbjct: 2438 --SPVTPRFQSPDPYSRPPSRPQS---RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAG 2492 Query: 363 QLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAALAAAGLSGGRHTQPAGP 422 A AG GE+ +P G + GT A + P Sbjct: 2493 GFPAALPAGPA--------GELHAKVPSGQPPNFVRSPGTGAFVGT-------------P 2531 Query: 423 GRAQRTEAAATQDCALDKPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSG 482 + T A + +L P+ P P G + P G Sbjct: 2532 SPMRFTFPQAVGEPSLKPPVP--------QPGLPPPHGINSHFGP--------------G 2569 Query: 483 PLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPH 542 P PQ+ +N T T + +P+ PS G LS PL PP Sbjct: 2570 PTLGKPQS-TNYTVAT--GNFHPSGSPLGPSSGSTGESYGLS------------PLRPPS 2614 Query: 543 PQPPPHPQP--PDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600 PPP P P L H ++ + P +++ + PG+ +G S T G Sbjct: 2615 VLPPPAPDGSLPYL-SHGASQRSGITSP----VEKREDPGTGMGSSLATAELPGTQDPGM 2669 Query: 601 ECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATE----GPGSPRDAEDHSPS 655 + E + R+R R + + R ++ A GP AE SP+ Sbjct: 2670 SGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPA 2728 Score = 42.7 bits (99), Expect = 0.001 Identities = 113/476 (23%), Positives = 154/476 (32%), Gaps = 89/476 (18%) Query: 184 PAGHRTSPVAKISPGATLPE----SRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPA 239 P R SP + P + LPE SR + SP + P + P P Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPLEESP-------------LSPPPEESPLSPPPE 508 Query: 240 NGTPPPL------PARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLN 293 + PL P SPPSPA E LS AS S E+P LSP + L Sbjct: 509 SSPFSPLEESPLSPPEESPPSPALETPLSPPP--EASPLSPPFEESP-LSPPPEELPTSP 565 Query: 294 RPLSLHLQSP-HSSPLAPAAAPSDPRLQDLKAREAEAWEE------PTEL-LGLPSALAG 345 P + L P SP++P S +R +EE P E L P + Sbjct: 566 PPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASR 625 Query: 346 MQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSEGPENEGTRAA 405 + + + + + + P P + P S PE T Sbjct: 626 LSPPPEDSPMSPPPEESPMSPPPEVSRLSPL--PVVSRLSPPPEESPLSPPPEESPTSPP 683 Query: 406 LAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEW----------GRARGQD- 454 A+ LS P P + +D + PL+ S R+ G Sbjct: 684 PEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHL 743 Query: 455 TPKPAGQHGSLSPAAAHTA--------SPEP---------------PTQSGP-LTRSPQA 490 +P+P H S P H + SP+P P GP L+ P+ Sbjct: 744 SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEE 803 Query: 491 LSNGTKGTRVPEQEEASTPMDPSRPL--PGSQLSLSSPGSTEDEDTGRP----LPPPHPQ 544 L P+ EE P P P + S SP S E + RP L P + Sbjct: 804 LHLS------PQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEK 857 Query: 545 PPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGP 600 PP P+P +P + P +EL PG E S GE P Sbjct: 858 PPLSPRPE------KPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPP 907 Score = 39.3 bits (90), Expect = 0.012 Identities = 124/587 (21%), Positives = 208/587 (35%), Gaps = 86/587 (14%) Query: 6 ESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRVLE 65 + + L+++ +++ L Q +L + ++ + Q++++ QL++QQ+ + L+ Sbjct: 3892 QPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQ-----QQLQQQQQQQQ-----LQ 3941 Query: 66 NRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVKRL 125 + + L + Q+ +++QQ+F+ Q Q+ L N+ L + +++V Sbjct: 3942 QQQQQQLQQQQQQLQQQQQQQQQQFQQ---QQQQQQMGLLNQSRTLLSPQQQQQQQV--- 3995 Query: 126 RVLGDRPKPRAKEGTSDPPS--PLLLPSPGGWKAITEKPPGGHEEAEEDHQGVGLRGEEK 183 LG + + S P + P LL + + E HQG L Sbjct: 3996 -ALGPGMPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTT 4054 Query: 184 PAGHRTSPVAKISPGATLPESR---APDMSPQRISNQLHGTIAVVRPGSQACPADRGPAN 240 P T P ++ P + P PQ S QL + + Q Sbjct: 4055 PESMATEP-GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGG 4113 Query: 241 GTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNRPLSLHL 300 G+ L + SS + + L+ S +P +MT L P+ +L RP+ + Sbjct: 4114 GSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNL--LGPQQP---MLERPMQNNT 4168 Query: 301 --QSPHSSPLAPAAAPSD-----PRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEG 353 Q P P+ + P + L+A+ + +L L+ Q +L+ Sbjct: 4169 GPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQL----RHLSPQQQQQLQA 4224 Query: 354 ALHLLLAQQQLRARARAGSVRPRGQPTPGEML----PSL---------PVGSDSEGPENE 400 L QQ R P Q +P + L P L P+ GP + Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQ 4284 Query: 401 GTRAALAAAG-LSGGRHTQPAGPGRAQRTEAAATQDCALDKP---LDLSEWGRARGQDTP 456 G A G LS G P P + + L P L TP Sbjct: 4285 GPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTP 4344 Query: 457 KPAG-----QHGSLSPAAAHTA--------SPEPPTQSGPLTRSPQALS------NGTKG 497 KP G G +SPAAA A P P + T+ P+ S + G Sbjct: 4345 KPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVPGHLDQVNG 4404 Query: 498 TRVPEQEEASTPMDPSRPLP---GSQLSLSSPGSTEDEDTGRPLPPP 541 VPE + S +P R P G+Q S + E G P+ P Sbjct: 4405 QVVPEASQLSIKQEP-REEPCALGAQ-------SVKREANGEPIGAP 4443 Score = 37.4 bits (85), Expect = 0.045 Identities = 112/487 (22%), Positives = 162/487 (33%), Gaps = 88/487 (18%) Query: 179 RGEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGP 238 + ++ A HR + V K + +++ D++ + LH I +PG Sbjct: 2063 KAKDNRAAHRINKVQKQAESQINKQTKVGDIARKTDRPALHLRIPP-QPG---------- 2111 Query: 239 ANGTPPPLPARS----SPPSPAYERGLSL--DSFLRASRPSAMTHEAP-----KLSPKVD 287 A G+PPP A + SP +PA GLS D FL+ S ++P KL P+V Sbjct: 2112 ALGSPPPAAAPTIFIGSPTTPA---GLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQVP 2168 Query: 288 RLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQ 347 P L P P P A P+ P A+ +LG S Q Sbjct: 2169 AQVPSQDPFGLAPAYP-LEPRFPTAPPTYPPYPSPTGAPAQP-----PMLGASSRPGAGQ 2222 Query: 348 DLRLEGALHLLLAQQQLRARARAGSVRPRGQP-TPGEML-PSLPVGSDSEGPENEGTRAA 405 G H PR QP TP L P P + PE+ G Sbjct: 2223 P----GEFHT------------TPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGG 2266 Query: 406 LAAAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLSEWGRAR--GQDTPKPAGQHG 463 A+ L P G +++ ++ P +G D+P G Sbjct: 2267 KASEPL-----LSPPPFGESRKALEVKKEELGASSP----SYGPPNLGFVDSPSSGTHLG 2317 Query: 464 SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSL 523 L P PLT + + G + QE P P P S + Sbjct: 2318 GLELKT-------PDVFKAPLTPRASQVEPQSPGLGLRPQEPP--PAQALAPSPPSHPDI 2368 Query: 524 SSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEV 583 PGS D PL P QPPP P L P S D P S V Sbjct: 2369 FRPGSYTDPYAQPPLTPRP-QPPP------------PESCCALPPRSLPSD----PFSRV 2411 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643 S Q++ ++S + P + + P R ++ +P + +P + R P Sbjct: 2412 PASPQSQ-SSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRP-QSRDPFAPLHKP 2469 Query: 644 GSPRDAE 650 P+ E Sbjct: 2470 PRPQPPE 2476 Score = 35.0 bits (79), Expect = 0.22 Identities = 63/267 (23%), Positives = 82/267 (30%), Gaps = 69/267 (25%) Query: 456 PKPAGQHGSLSPAAAHTASPEPPTQSGPLTRS------------PQALSNGTKGTRVPEQ 503 P G GS PAAA T PT L+ S P S G ++P Q Sbjct: 2107 PPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPPAGSVPGPDSPGELFLKLPPQ 2166 Query: 504 EEASTP-MDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQP------PP--------- 547 A P DP P L P T P PP+P P PP Sbjct: 2167 VPAQVPSQDPFGLAPAYPLEPRFP-------TAPPTYPPYPSPTGAPAQPPMLGASSRPG 2219 Query: 548 -------HPQPPDLDGHPEPSKAEVLRPESDELDE---TDTPGSEVGLSSQAEATTSTTG 597 H PP H + L+P LD ++PG G +S+ + G Sbjct: 2220 AGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFG 2279 Query: 598 EGPECICTQEH-------GQGPPR-----KRKRASEPGDKASKKPSRGRRKLTATEG--- 642 E + + ++ GPP + G K P + LT Sbjct: 2280 ESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE 2339 Query: 643 ---------PGSPRDAEDHSPSPNSSP 660 P P A+ +PSP S P Sbjct: 2340 PQSPGLGLRPQEPPPAQALAPSPPSHP 2366 Score = 34.3 bits (77), Expect = 0.38 Identities = 36/133 (27%), Positives = 49/133 (36%), Gaps = 16/133 (12%) Query: 168 EAEEDHQGVGLRGEEKPAGHRTSPVAKISPGATLPESRA-----PDMSPQRISNQLHGTI 222 + E G+GLR +E P +P P P S P ++P+ Sbjct: 2337 QVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC 2396 Query: 223 AVVRPGSQACPADRGPANG----------TPPPLPARSSPPSPAYERGLSLDSFLR-ASR 271 A+ + P R PA+ TP PL A + PSP R S D + R SR Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSR 2456 Query: 272 PSAMTHEAPKLSP 284 P + AP P Sbjct: 2457 PQSRDPFAPLHKP 2469 Score = 31.6 bits (70), Expect = 2.5 Identities = 50/226 (22%), Positives = 77/226 (34%), Gaps = 23/226 (10%) Query: 456 PKPAGQHGSLSPAAAHTASPEPPTQSGPLTRS---PQALSNGTKGTRVPEQEEASTPMDP 512 P+P GSL+ + P + P+T P+ +G+ EQEE P+ P Sbjct: 1135 PEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPVAP 1194 Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHP---QPPPH-----PQPPDLDGHPEPSKAE 564 + P ++ + D P P P P + P++ E Sbjct: 1195 TPPTLIKSDIVNEISNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVSTDVSPARDE 1254 Query: 565 -VLRPESDELDETD-----TPGSEV-GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRK 617 LR +D L ETD G+ + G ++ E + I P R+R Sbjct: 1255 GSLRLCTDSLPETDDSLLCDAGTAISGGKAEGEKGRRRSSPARSRIKQGRSSSFPGRRRP 1314 Query: 618 RASEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSPSPNSSPWEE 663 R G + RGR +L +T D SP+ EE Sbjct: 1315 RGGAHGGR-----GRGRARLKSTASSIETLVVADIDSSPSKEEEEE 1355 Score = 30.0 bits (66), Expect = 7.1 Identities = 66/252 (26%), Positives = 96/252 (38%), Gaps = 54/252 (21%) Query: 131 RPKPRAKEGTSDPPSPLLLPSPGGWKAITEKPP-GGHEEAEEDHQGVGLRGEEKPAGHRT 189 RP P A + D S L+ GG +A ++ P G ++ Q + +++ A T Sbjct: 2774 RPPPPATPSSMDVNSRQLV---GGSQAFYQRAPYPGSLPLQQQQQQLW---QQQQATAAT 2827 Query: 190 SPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRGPA---------- 239 S + + A P + P++ Q + + L G + + P GPA Sbjct: 2828 S--MRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQ 2885 Query: 240 -----NGTP-----PPLPARSSPPS-------PAYERGLSLDSFLRASRPSAMTHEAPKL 282 GTP PP R P S P RGL++ S L +PSA AP+L Sbjct: 2886 KGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAV-SGLPPQKPSA--PPAPEL 2942 Query: 283 SPKV------------DRLCLLNR-PLSLHLQSPHSSPLAPAAAP-SDPRL-QDLKAREA 327 + + L L+NR P S L P+ L P DP L D A +A Sbjct: 2943 NNSLHPTPHTKGPTLPTGLELVNRPPSSTELGRPNPLALEAGKLPCEDPELDDDFDAHKA 3002 Query: 328 EAWEEPTELLGL 339 +E LGL Sbjct: 3003 LEDDEELAHLGL 3014 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 53.9 bits (128), Expect = 5e-07 Identities = 112/494 (22%), Positives = 151/494 (30%), Gaps = 87/494 (17%) Query: 134 PRAKEGTSDPPSP---LLLPSPGGW--KAITEKPPGGHEEAEEDHQG------VGLR--- 179 P A G + PP P L SPG ++T + A D G +G R Sbjct: 601 PPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVI 660 Query: 180 --GEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRISNQLHGTIAVVRPGSQACPADRG 237 + PA P SP P AP + P +S + P + P Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQES 720 Query: 238 PA---NGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLSPKVDRLCLLNR 294 P + +PPP P S P P + +P + EAP S + Sbjct: 721 PVISKDQSPPPSPPPSYHPPPPPTK-----------KPEVVV-EAPSASETAEE------ 762 Query: 295 PLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAEAWEEPTELLGLPSALAGMQDLRLEGA 354 P P P P P QDL + EE + P G+ Sbjct: 763 --------PLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP------SGS 808 Query: 355 LHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSL-----------------PVG-SDSEG 396 L+ + + A A ++P G P P P+ PVG S G Sbjct: 809 PELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGG 868 Query: 397 PENEGTRAALA-----------AAGLSGGRHTQPAGPGRAQRTEAAATQDCALDKPLDLS 445 P E A L + G GG T GP Q+ A A P S Sbjct: 869 PPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSS 928 Query: 446 EWGRARGQDTPKPAGQHG--SLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQ 503 A A G S P A P PP P + + S G++ ++ Sbjct: 929 GLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPP--QSPASTASFIFSKGSRKLQLERP 986 Query: 504 EEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKA 563 T D R L S+S + PPP + P PP P +A Sbjct: 987 VSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPP--PASPSYPRA 1044 Query: 564 EVL-RPESDELDET 576 E L P ++ L T Sbjct: 1045 EPLTAPPTNGLPHT 1058 Score = 53.1 bits (126), Expect = 8e-07 Identities = 117/495 (23%), Positives = 167/495 (33%), Gaps = 86/495 (17%) Query: 224 VVRPGSQACPADRGPANGTPPPLPARSSPPSPAYERGLSLDSFLRASRPSAMTHEAPKLS 283 + RP S A P G A P PA S P Y L P A+ L Sbjct: 317 LTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATY---------LSKLIPHAV------LP 361 Query: 284 PKVDRLCLLNRPL------SLHLQSPHS-SPLAPAAAPSDPRLQDLK-AREAEAWEEPTE 335 P VD + L L SLH SP S L ++ S P+ + + ++ W Sbjct: 362 PTVDVVALGRCSLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQS 421 Query: 336 LLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSDSE 395 + ++ L +G ++ Q + + SV P Q G PS GS +E Sbjct: 422 S---DTIVSDGSTLSSKGG-----SEGQPESSTASNSVVPPPQGGSGRGSPS--GGSTAE 471 Query: 396 GPENEGTRAALAAAGLSGGRHTQPAGPGRAQRTEAAATQDCAL-DKPLDLSEWGRARGQ- 453 + R++ +G S P +RT + + A+ D PL L + Q Sbjct: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGLAVPDGPLGLPPKPERKQQP 531 Query: 454 DTPKPAGQHGSLSPAAAHTASPEP---------------PTQSGPLTRSPQALSNGTKGT 498 P+P GS AA P P P +S T SP + + GT Sbjct: 532 QLPRPPTTGGSEGAGAA-PCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYSSQSGT 590 Query: 499 -RVPEQEEASTPMDPSR---PLPGSQLSLSSPGSTEDED-------TGRPLP-------- 539 +P + A P P + P P SL SPG++ + P P Sbjct: 591 PTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQI 650 Query: 540 ----------PPHPQ-PPPHPQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQ 588 PPHP+ P P PP P P+ + P P S S Q Sbjct: 651 LTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAV-----VPGPVSTTDASPQ 705 Query: 589 AEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPRD 648 + T TT + Q PP + P +KKP +A+E P Sbjct: 706 SPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQ 765 Query: 649 AEDHSPSPNSSPWEE 663 + P P +P E+ Sbjct: 766 DPNWPPPPPPAPEEQ 780 Score = 45.1 bits (105), Expect = 2e-04 Identities = 48/185 (25%), Positives = 71/185 (38%), Gaps = 11/185 (5%) Query: 467 PAAAHTASPE-PPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDPSRPLPGSQLSLSS 525 P + ASP+ PPT LT ++ + P + P P P + S Sbjct: 696 PVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPS 755 Query: 526 PGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPEPSKA--EVLRPESDELDETDTPGSEV 583 T +E P PP P P P Q + P P +A V PE GS Sbjct: 756 ASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPE-----PAGPSGSPE 810 Query: 584 GLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGP 643 +SS A +++S T + + + PP +S PG A K P + + ++G Sbjct: 811 LVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVA-KLPQ--KEPVGCSKGG 867 Query: 644 GSPRD 648 G PR+ Sbjct: 868 GPPRE 872 Score = 30.8 bits (68), Expect = 4.2 Identities = 63/257 (24%), Positives = 86/257 (33%), Gaps = 53/257 (20%) Query: 139 GTSDPPSPLLLPSP-----GGWKAITEKPPGGHEEA----EEDH----------QGVGLR 179 G+ DPP P+P G + +K P G + ED Q V LR Sbjct: 831 GSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLR 890 Query: 180 GEEKPAGHRTSPVAKISPGATLPESRAPDMSPQRI-SNQLHGTI-------AVVRPGSQA 231 P G T + +P L + + SP S+ LH + A S A Sbjct: 891 SVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSA 950 Query: 232 CPADRGPANGTPPPLPARSS---------------PPSPAYERGL--SLDSFLRA---SR 271 P A PP PA ++ P SP + L +L + LR+ R Sbjct: 951 QPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQR 1010 Query: 272 PSAMTHEAPKLSPKVDRLCLLNRPLSLHLQSPHSSPLAPAAAPSDPRLQDLKAREAE--- 328 P ++PK P V R + P P + PL P QD RE Sbjct: 1011 PPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTKRELAENG 1070 Query: 329 ---AWEEPTELLGLPSA 342 P E +GLP + Sbjct: 1071 GVLQLVGPEEKMGLPGS 1087 >gi|37537692 proline-rich protein BstNI subfamily 4 precursor [Homo sapiens] Length = 247 Score = 53.9 bits (128), Expect = 5e-07 Identities = 58/232 (25%), Positives = 89/232 (38%), Gaps = 27/232 (11%) Query: 336 LLGLPSALAGMQDLRLEGALHLLLAQQQLRARARAGSVRPRGQPTPGEMLPSLPVGSD-S 394 LL L SA + +D+ E +L L+ + + R R + G+ R P PG+ P G + S Sbjct: 10 LLALSSAESSSEDVSQEESLFLISGKPEGR-RPQGGNQPQRPPPPPGKPQGPPPQGGNQS 68 Query: 395 EGPENEGTRAALAAAGLSGGRHTQ--PAGPGRAQRTEAAATQDCALDKPLDLSEWGRARG 452 +GP + GG +Q P PG+ +R G + Sbjct: 69 QGPPPPPGKPE--GRPPQGGNQSQGPPPHPGKPERPPPQ----------------GGNQS 110 Query: 453 QDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTRVPEQEEASTPMDP 512 Q TP P G+ P + + PP P PQ + P + E P + Sbjct: 111 QGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHPGKPEGPPPQEG 170 Query: 513 SRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQ-PPDLDGHPEPSKA 563 ++ S+ + S PG + P P PP PQ PP G+P+ +A Sbjct: 171 NK----SRSARSPPGKPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQA 218 Score = 42.7 bits (99), Expect = 0.001 Identities = 50/215 (23%), Positives = 71/215 (33%), Gaps = 25/215 (11%) Query: 440 KPLDLSEWGRARGQDTPKPAGQHGSLSPAAAHTASPEPPTQSGPLTRSPQALSNGTKGTR 499 KP G + Q P P G+ P + + PP P PQ N ++GT Sbjct: 56 KPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPHPGKPERPPPQG-GNQSQGTP 114 Query: 500 VPEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQPPPHPQPPDLDGHPE 559 P P P RP P + RP PPP P PQ + P Sbjct: 115 PP-------PGKPERPPPQG-----------GNQSHRPPPPPGKPERPPPQGGNQSQGPP 156 Query: 560 PSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEHGQGPPRKRKRA 619 P + P E +++ + S G + + G P+ QGPP Sbjct: 157 PHPGKPEGPPPQEGNKSRSARSPPG---KPQGPPQQEGNKPQGPPPPGKPQGPPPAGGNP 213 Query: 620 SEPGDKASKKPSRGRRKLTATEGPGSPRDAEDHSP 654 +P + KP + +G PR A+ P Sbjct: 214 QQPQAPPAGKP---QGPPPPPQGGRPPRPAQGQQP 245 Score = 37.7 bits (86), Expect = 0.034 Identities = 37/159 (23%), Positives = 49/159 (30%), Gaps = 22/159 (13%) Query: 501 PEQEEASTPMDPSRPLPGSQLSLSSPGSTEDEDTGRPLPPPHPQ------------PPPH 548 PE P RP P P ++ G P PP P+ PPPH Sbjct: 36 PEGRRPQGGNQPQRPPPPPGKPQGPPPQGGNQSQGPPPPPGKPEGRPPQGGNQSQGPPPH 95 Query: 549 PQPPDLDGHPEPSKAEVLRPESDELDETDTPGSEVGLSSQAEATTSTTGEGPECICTQEH 608 P P+ P P + + + P + G S E P + Sbjct: 96 PGKPE---RPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQ- 151 Query: 609 GQGPPRKRKRASEPGDKASKKPSRGRRKLTATEGPGSPR 647 QGPP PG P G + +A PG P+ Sbjct: 152 SQGPPPH------PGKPEGPPPQEGNKSRSARSPPGKPQ 184 Score = 35.0 bits (79), Expect = 0.22 Identities = 42/145 (28%), Positives = 53/145 (36%), Gaps = 22/145 (15%) Query: 130 DRPKPRA---KEGTSDPPSPLLLPSP-GGWKAITEKPPGGHEEAEEDHQGVGLRGEEKPA 185 +RP P+ +GT PP P P GG ++ PP G E G +G Sbjct: 100 ERPPPQGGNQSQGTPPPPGKPERPPPQGGNQSHRPPPPPGKPERPPPQGGNQSQGPPPHP 159 Query: 186 GHRTSPVAKI---SPGATLPESRAPDMSPQRISNQLHGTIAVVRPGS-----------QA 231 G P + S A P + P PQ+ N+ G +P QA Sbjct: 160 GKPEGPPPQEGNKSRSARSPPGK-PQGPPQQEGNKPQGPPPPGKPQGPPPAGGNPQQPQA 218 Query: 232 CPADRGPANGTPPPLPARSSPPSPA 256 PA G G PPP P PP PA Sbjct: 219 PPA--GKPQGPPPP-PQGGRPPRPA 240 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.308 0.128 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,309,307 Number of Sequences: 37866 Number of extensions: 2520507 Number of successful extensions: 30191 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 381 Number of HSP's successfully gapped in prelim test: 2060 Number of HSP's that attempted gapping in prelim test: 15519 Number of HSP's gapped (non-prelim): 10803 length of query: 664 length of database: 18,247,518 effective HSP length: 109 effective length of query: 555 effective length of database: 14,120,124 effective search space: 7836668820 effective search space used: 7836668820 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.