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Search of human proteins with 24308277
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24308277 SPARC related modular calcium binding 2 [Homo
sapiens]
(457 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens] 959 0.0
gi|78190498 secreted modular calcium-binding protein 1 isoform 1... 482 e-136
gi|11545873 secreted modular calcium-binding protein 1 isoform 2... 480 e-135
gi|55770862 thyroglobulin [Homo sapiens] 79 1e-14
gi|144953895 nidogen 2 precursor [Homo sapiens] 77 2e-14
gi|115298674 nidogen 1 precursor [Homo sapiens] 59 1e-08
gi|7662036 sparc/osteonectin, cwcv and kazal-like domains proteo... 56 6e-08
gi|4759164 sparc/osteonectin, cwcv and kazal-like domains proteo... 52 1e-06
gi|5453652 follistatin isoform FST317 precursor [Homo sapiens] 51 2e-06
gi|7242222 follistatin isoform FST344 precursor [Homo sapiens] 51 2e-06
gi|68448544 CD74 antigen isoform a [Homo sapiens] 49 7e-06
gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens] 49 9e-06
gi|62243068 insulin-like growth factor binding protein 3 isoform... 48 2e-05
gi|62243248 insulin-like growth factor binding protein 3 isoform... 48 2e-05
gi|4504615 insulin-like growth factor binding protein 1 precurso... 47 3e-05
gi|93141003 testican 3 isoform 1 [Homo sapiens] 47 3e-05
gi|93141001 testican 3 isoform 2 [Homo sapiens] 47 3e-05
gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens] 47 4e-05
gi|12383051 transmembrane protein with EGF-like and two follista... 47 5e-05
gi|29568105 transmembrane protein with EGF-like and two follista... 46 6e-05
gi|62243290 insulin-like growth factor binding protein 4 precurs... 44 3e-04
gi|54873613 agrin [Homo sapiens] 44 4e-04
gi|190194423 SPARC-like 1 [Homo sapiens] 44 4e-04
gi|190341024 SPARC-like 1 [Homo sapiens] 44 4e-04
gi|55925576 insulin-like growth factor binding protein 2, 36kDa ... 41 0.003
gi|11321593 insulin-like growth factor binding protein 6 [Homo s... 40 0.003
gi|5901956 follistatin-like 1 precursor [Homo sapiens] 39 0.008
gi|149408146 TOX high mobility group box family member 2 isoform... 38 0.017
gi|215983090 guanylate cyclase activator 1C [Homo sapiens] 37 0.037
gi|10834982 insulin-like growth factor binding protein 5 [Homo s... 36 0.064
>gi|24308277 SPARC related modular calcium binding 2 [Homo sapiens]
Length = 457
Score = 959 bits (2479), Expect = 0.0
Identities = 457/457 (100%), Positives = 457/457 (100%)
Query: 1 MLLPQLCWLPLLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTF 60
MLLPQLCWLPLLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTF
Sbjct: 1 MLLPQLCWLPLLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTF 60
Query: 61 LSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYS 120
LSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYS
Sbjct: 61 LSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYS 120
Query: 121 QVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQREGTGKTVSLQIFSVLN 180
QVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQREGTGKTVSLQIFSVLN
Sbjct: 121 QVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQREGTGKTVSLQIFSVLN 180
Query: 181 SDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQ 240
SDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQ
Sbjct: 181 SDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQ 240
Query: 241 PKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHP 300
PKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHP
Sbjct: 241 PKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHP 300
Query: 301 AKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSHTLEE 360
AKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSHTLEE
Sbjct: 301 AKARDLYKGRQLQGCPGAKKHEFLTSVLDALSTDMVHAASDPSSSSGRLSEPDPSHTLEE 360
Query: 361 RVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQEL 420
RVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQEL
Sbjct: 361 RVVHWYFKLLDKNSSGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQEL 420
Query: 421 MGCLGVAKEDGKADTKKRHTPRGHAESTSNRQPRKQG 457
MGCLGVAKEDGKADTKKRHTPRGHAESTSNRQPRKQG
Sbjct: 421 MGCLGVAKEDGKADTKKRHTPRGHAESTSNRQPRKQG 457
>gi|78190498 secreted modular calcium-binding protein 1 isoform 1
[Homo sapiens]
Length = 435
Score = 482 bits (1240), Expect = e-136
Identities = 228/409 (55%), Positives = 296/409 (72%), Gaps = 24/409 (5%)
Query: 35 DKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDV--SRCVA 92
D+D C+L C+ + KP+CASDGR++ S CE+QRAKC+DP L + +RG CKD S+C
Sbjct: 38 DRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRL 97
Query: 93 ERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPR 152
ER EQA+K + VF+PEC +DG+++QVQCH+YTGYCWCVTP+G+PISG++V +KTP
Sbjct: 98 ERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV 157
Query: 153 CPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAA--APALETQPQGDEEDIASRYPTLWTE 210
C GSV +K + +G+ DD + P +ETQP D ++I + PTLW +
Sbjct: 158 CSGSVTDKPLSQGNSGR-----------KDDGSKPTPTMETQPVFDGDEITA--PTLWIK 204
Query: 211 QVKSRQNKTNKNSVS------SCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHP 264
+ + +K N ++ SCDQE QSALEEA+Q + +VIPECA GGLYKPVQCH
Sbjct: 205 HLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQ 264
Query: 265 STGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKGRQLQGCPGAKKHEFL 324
STGYCWCVLVDTGRP+PGTSTRY P C++ ARA +A D +K R+L GCP KK EF+
Sbjct: 265 STGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFI 324
Query: 325 TSVLDALSTDMVHAASDPS-SSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEI 383
TS+LDAL+TDMV A + + + GR SEPDPSHTLEERVVHWYF LD NSS DI K+E+
Sbjct: 325 TSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREM 384
Query: 384 KPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELMGCLGVAKEDGK 432
KPFKR+++KK+KPKKC ++F +YCD+N DK IS+ EL GCLGV+KE G+
Sbjct: 385 KPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKEVGR 433
>gi|11545873 secreted modular calcium-binding protein 1 isoform 2
[Homo sapiens]
Length = 434
Score = 480 bits (1235), Expect = e-135
Identities = 227/406 (55%), Positives = 294/406 (72%), Gaps = 24/406 (5%)
Query: 35 DKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDV--SRCVA 92
D+D C+L C+ + KP+CASDGR++ S CE+QRAKC+DP L + +RG CKD S+C
Sbjct: 38 DRDPQCNLHCSRTQPKPICASDGRSYESMCEYQRAKCRDPTLGVVHRGRCKDAGQSKCRL 97
Query: 93 ERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPR 152
ER EQA+K + VF+PEC +DG+++QVQCH+YTGYCWCVTP+G+PISG++V +KTP
Sbjct: 98 ERAQALEQAKKPQEAVFVPECGEDGSFTQVQCHTYTGYCWCVTPDGKPISGSSVQNKTPV 157
Query: 153 CPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAA--APALETQPQGDEEDIASRYPTLWTE 210
C GSV +K + +G+ DD + P +ETQP D ++I + PTLW +
Sbjct: 158 CSGSVTDKPLSQGNSGR-----------KDDGSKPTPTMETQPVFDGDEITA--PTLWIK 204
Query: 211 QVKSRQNKTNKNSVS------SCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHP 264
+ + +K N ++ SCDQE QSALEEA+Q + +VIPECA GGLYKPVQCH
Sbjct: 205 HLVIKDSKLNNTNIRNSEKVYSCDQERQSALEEAQQNPREGIVIPECAPGGLYKPVQCHQ 264
Query: 265 STGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKARDLYKGRQLQGCPGAKKHEFL 324
STGYCWCVLVDTGRP+PGTSTRY P C++ ARA +A D +K R+L GCP KK EF+
Sbjct: 265 STGYCWCVLVDTGRPLPGTSTRYVMPSCESDARAKTTEADDPFKDRELPGCPEGKKMEFI 324
Query: 325 TSVLDALSTDMVHAASDPS-SSSGRLSEPDPSHTLEERVVHWYFKLLDKNSSGDIGKKEI 383
TS+LDAL+TDMV A + + + GR SEPDPSHTLEERVVHWYF LD NSS DI K+E+
Sbjct: 325 TSLLDALTTDMVQAINSAAPTGGGRFSEPDPSHTLEERVVHWYFSQLDSNSSNDINKREM 384
Query: 384 KPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELMGCLGVAKE 429
KPFKR+++KK+KPKKC ++F +YCD+N DK IS+ EL GCLGV+KE
Sbjct: 385 KPFKRYVKKKAKPKKCARRFTDYCDLNKDKVISLPELKGCLGVSKE 430
>gi|55770862 thyroglobulin [Homo sapiens]
Length = 2768
Score = 78.6 bits (192), Expect = 1e-14
Identities = 57/211 (27%), Positives = 91/211 (43%), Gaps = 20/211 (9%)
Query: 109 FIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG--TAVAHKTPRCPGSVNEKLPQREG 166
++P+C+ G++ VQCH+ TG+CWCV G I G TA + + P+CP + E
Sbjct: 1027 YMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLTARSLQIPQCPTTC-------EK 1079
Query: 167 TGKTVSLQIFSVLNSDDAAAP-------ALETQPQGDEEDIASRYPTLWTEQVKSRQNKT 219
+ + L + S + +P LET + AS T + + +
Sbjct: 1080 SRTSGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQ--ASGAGTWCVDPASGEELRP 1137
Query: 220 NKNSVSSCDQEHQSALEEAKQPKNDNVVIPEC-AHGGLYKPVQCHPSTGYCWCVLVDTGR 278
+S + C + +P C A G + PVQC + G CWCV+ D+G
Sbjct: 1138 GSSSSAQCPSLCNVLKSGVLSRRVSPGYVPACRAEDGGFSPVQCDQAQGSCWCVM-DSGE 1196
Query: 279 PIPGTSTRYEQPKCDNTARAHPAKARDLYKG 309
+PGT QP C++ P A ++ G
Sbjct: 1197 EVPGTRVTGGQPACESPRCPLPFNASEVVGG 1227
Score = 54.3 bits (129), Expect = 2e-07
Identities = 55/203 (27%), Positives = 78/203 (38%), Gaps = 31/203 (15%)
Query: 117 GTYSQVQ---CHSYTGYCWCVTPNGRPISG-TAVAHKTPRCPGSVNE-KLPQREGTGKTV 171
G+YS H CWCV G+ + G + K P CPGS E KL + +T
Sbjct: 881 GSYSDFSTPLAHFDLRNCWCVDEAGQELEGMRSEPSKLPTCPGSCEEAKLRVLQFIRETE 940
Query: 172 SL------------QIFSV-----LNSDDAAAPALETQPQGDEEDIASRYPTLWTEQVKS 214
+ + F V L ++D P L + E +S
Sbjct: 941 EIVSASNSSRFPLGESFLVAKGIRLRNEDLGLPPLFPPREAFAEQFLRGSDYAIRLAAQS 1000
Query: 215 RQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLV 274
+ + S D SAL +P+C G ++PVQCH TG+CWCV
Sbjct: 1001 TLSFYQRRRFSPDDSAGASAL------LRSGPYMPQCDAFGSWEPVQCHAGTGHCWCV-D 1053
Query: 275 DTGRPIPG--TSTRYEQPKCDNT 295
+ G IPG T+ + P+C T
Sbjct: 1054 EKGGFIPGSLTARSLQIPQCPTT 1076
Score = 53.5 bits (127), Expect = 4e-07
Identities = 22/64 (34%), Positives = 36/64 (56%), Gaps = 2/64 (3%)
Query: 91 VAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKT 150
V E + + + +++F+P C +G+Y VQC ++G CWCV G+ + G+ V
Sbjct: 598 VMETVLSSQTCEQTPERLFVPSCTTEGSYEDVQC--FSGECWCVNSWGKELPGSRVRGGQ 655
Query: 151 PRCP 154
PRCP
Sbjct: 656 PRCP 659
Score = 49.3 bits (116), Expect = 7e-06
Identities = 31/114 (27%), Positives = 44/114 (38%), Gaps = 8/114 (7%)
Query: 51 PLCASDGRTFLSRCEFQRAKCKDPQLEIAYRGNCKDVSRCVAERKYTQEQARK------- 103
P CA DG +C+ C + + R VA + Q Q ++
Sbjct: 50 PQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGYI 109
Query: 104 -EFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGS 156
++P+C D G Y+ VQC CWCV G + GT + RCP S
Sbjct: 110 NSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQLGRPKRCPRS 163
Score = 45.4 bits (106), Expect = 1e-04
Identities = 40/167 (23%), Positives = 65/167 (38%), Gaps = 27/167 (16%)
Query: 106 QQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRCPGSVNEKLPQRE 165
Q ++P+C +DG++ VQC + CWCV NG + G+ + C + Q
Sbjct: 45 QADYVPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQ-- 102
Query: 166 GTGKTVSLQIFSVLNSDDAAAPALETQPQGDEEDIAS--RYPTLW------TEQVKSRQN 217
+ + +NS D + + Q GD + + W E +RQ
Sbjct: 103 -------ILLSGYINSTDTSY-LPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYGTRQL 154
Query: 218 KTNKNSVSSCDQEHQSALEEA--KQPKNDNVVIPECAHGGLYKPVQC 262
K SC+ ++ L K P P+C+ G + PVQC
Sbjct: 155 GRPKRCPRSCEIRNRRLLHGVGDKSP-------PQCSAEGEFMPVQC 194
Score = 44.3 bits (103), Expect = 2e-04
Identities = 21/63 (33%), Positives = 32/63 (50%), Gaps = 3/63 (4%)
Query: 244 DNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDNTARAHPAKA 303
+ + +P C G Y+ VQC +G CWCV G+ +PG+ R QP+C A+
Sbjct: 613 ERLFVPSCTTEGSYEDVQCF--SGECWCV-NSWGKELPGSRVRGGQPRCPTDCEKQRARM 669
Query: 304 RDL 306
+ L
Sbjct: 670 QSL 672
Score = 43.5 bits (101), Expect = 4e-04
Identities = 18/49 (36%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 105 FQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRC 153
F ++P C +G Y VQC + G CWCV G+ + GT + P C
Sbjct: 311 FGHPYVPSCRRNGDYQAVQCQT-EGPCWCVDAQGKEMHGTRQQGEPPSC 358
Score = 41.6 bits (96), Expect = 0.002
Identities = 25/84 (29%), Positives = 34/84 (40%), Gaps = 1/84 (1%)
Query: 209 TEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGY 268
+E + SRQ +S C + Q L D +P+C G Y PVQC
Sbjct: 78 SEVLGSRQPGRPVACLSFCQLQKQQILLSGYINSTDTSYLPQCQDSGDYAPVQCDVQQVQ 137
Query: 269 CWCVLVDTGRPIPGTSTRYEQPKC 292
CWCV + G + GT +C
Sbjct: 138 CWCVDAE-GMEVYGTRQLGRPKRC 160
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/52 (38%), Positives = 28/52 (53%), Gaps = 3/52 (5%)
Query: 240 QPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPK 291
QP + +P C G + PVQC S C+CV + G+ IPGT + +PK
Sbjct: 676 QPAGSTLFVPACTSEGHFLPVQCFNSE--CYCVDAE-GQAIPGTRSAIGKPK 724
Score = 38.1 bits (87), Expect = 0.017
Identities = 18/48 (37%), Positives = 26/48 (54%), Gaps = 3/48 (6%)
Query: 108 VFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVA-HKTPRCP 154
+F+P C +G + VQC + C+CV G+ I GT A K +CP
Sbjct: 682 LFVPACTSEGHFLPVQC--FNSECYCVDAEGQAIPGTRSAIGKPKKCP 727
Score = 33.1 bits (74), Expect = 0.54
Identities = 11/25 (44%), Positives = 15/25 (60%)
Query: 248 IPECAHGGLYKPVQCHPSTGYCWCV 272
+P+CA G ++ VQC CWCV
Sbjct: 49 VPQCAEDGSFQTVQCQNDGRSCWCV 73
Score = 29.6 bits (65), Expect = 5.9
Identities = 22/91 (24%), Positives = 33/91 (36%), Gaps = 16/91 (17%)
Query: 51 PLCASDGRTFLSRCEFQRAKCKDPQLEI--AYRGNCKDVSRCVAERKYTQEQARKEFQQV 108
P C S+G +C C D + + R +C + EQA Q
Sbjct: 685 PACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAIGKPKKCPTPCQLQSEQAFLRTVQA 744
Query: 109 --------------FIPECNDDGTYSQVQCH 125
+IP+C+ DG + QVQC+
Sbjct: 745 LLSNSSMLPTLSDTYIPQCSTDGQWRQVQCN 775
>gi|144953895 nidogen 2 precursor [Homo sapiens]
Length = 1375
Score = 77.4 bits (189), Expect = 2e-14
Identities = 51/198 (25%), Positives = 81/198 (40%), Gaps = 61/198 (30%)
Query: 90 CVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHK 149
C ++++ Q Q + IP+C++ G + +QCH TG+CWCV P+G + GT +
Sbjct: 940 CEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGT----Q 995
Query: 150 TPRCPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAAAPALETQPQ-GDEEDIASRYPTLW 208
TP PGS T P G + R PT+
Sbjct: 996 TP--PGS----------------------------------TPPHCGPSPEPTQRPPTI- 1018
Query: 209 TEQVKSRQNKTNKNSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGY 268
C++ ++ LE D+ +P+C G + P+QCH + +
Sbjct: 1019 ------------------CERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDF 1060
Query: 269 CWCVLVDTGRPIPGTSTR 286
CWCV D GR + GT ++
Sbjct: 1061 CWCVDKD-GREVQGTRSQ 1077
Score = 55.5 bits (132), Expect = 1e-07
Identities = 26/64 (40%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Query: 222 NSVSSCDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIP 281
+S++ C+Q+ + A + P IP+C G + P+QCH STG+CWCV D G +P
Sbjct: 935 SSLTPCEQQQRHAQAQYAYP-GARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPD-GHEVP 992
Query: 282 GTST 285
GT T
Sbjct: 993 GTQT 996
Score = 48.5 bits (114), Expect = 1e-05
Identities = 18/46 (39%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Query: 109 FIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGT-AVAHKTPRC 153
++P+C+D G + +QCH + +CWCV +GR + GT + TP C
Sbjct: 1039 YVPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPAC 1084
>gi|115298674 nidogen 1 precursor [Homo sapiens]
Length = 1247
Score = 58.5 bits (140), Expect = 1e-08
Identities = 31/83 (37%), Positives = 42/83 (50%), Gaps = 7/83 (8%)
Query: 88 SRCVAERKYTQEQARKEFQQ------VFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPI 141
+RC ER++ A Q +F+PEC+ G Y+ QCH TGYCWCV +GR +
Sbjct: 847 TRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCHGSTGYCWCVDRDGREV 906
Query: 142 SGTAV-AHKTPRCPGSVNEKLPQ 163
GT TP C +V + Q
Sbjct: 907 EGTRTRPGMTPPCLSTVAPPIHQ 929
Score = 57.4 bits (137), Expect = 3e-08
Identities = 61/203 (30%), Positives = 79/203 (38%), Gaps = 27/203 (13%)
Query: 110 IPECNDD----GTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPR----CP-GSVNEK 160
I EC++ G+++ H T C CV GT VA R C G N
Sbjct: 711 IDECSEQPSVCGSHTICNNHPGTFRCECVEGYQFSDEGTCVAVVDQRPINYCETGLHNCD 770
Query: 161 LPQREGT----GKTVSLQIFSVLNSDDAAAPAL-ETQPQGDEED-IASRYPTLWTEQVKS 214
+PQR G + + + D A + E QP D P +T Q K
Sbjct: 771 IPQRAQCIYTGGSSYTCSCLPGFSGDGQACQDVDECQPSRCHPDAFCYNTPGSFTCQCKP 830
Query: 215 RQNKTNKNSV------SSCDQEHQSALEEA-----KQPKNDNVVIPECAHGGLYKPVQCH 263
V + C E + L A ++P + +PEC G Y P QCH
Sbjct: 831 GYQGDGFRCVPGEVEKTRCQHEREHILGAAGATDPQRPIPPGLFVPECDAHGHYAPTQCH 890
Query: 264 PSTGYCWCVLVDTGRPIPGTSTR 286
STGYCWCV D GR + GT TR
Sbjct: 891 GSTGYCWCVDRD-GREVEGTRTR 912
>gi|7662036 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan (testican) 2 isoform 2 [Homo sapiens]
Length = 424
Score = 56.2 bits (134), Expect = 6e-08
Identities = 33/99 (33%), Positives = 53/99 (53%), Gaps = 8/99 (8%)
Query: 58 RTFLSRCEFQRAKCKDPQLEIAYRGNC--KDVSRCVAERKYTQ-EQARKEFQQVFIPECN 114
R F + C+ KD ++ A C ++ C+AE + Q ++A K+ +FIP C+
Sbjct: 283 RPFFNSCDTY----KDGRVSTAEWCFCFWREKPPCLAELERIQIQEAAKKKPGIFIPSCD 338
Query: 115 DDGTYSQVQCHSYTGYCWCVTPNGRPISGTAVAHKTPRC 153
+DG Y ++QC +G CWCV G ++GT H +P C
Sbjct: 339 EDGYYRKMQCDQSSGDCWCVDQLGLELTGTR-THGSPDC 376
Score = 44.7 bits (104), Expect = 2e-04
Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 3/60 (5%)
Query: 235 LEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTRYEQPKCDN 294
++EA + K + IP C G Y+ +QC S+G CWCV G + GT T + P CD+
Sbjct: 322 IQEAAK-KKPGIFIPSCDEDGYYRKMQCDQSSGDCWCV-DQLGLELTGTRT-HGSPDCDD 378
Score = 30.4 bits (67), Expect = 3.5
Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 30 LRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNC 84
+++ +KD C C + +C SDG T+ S C+ ++ C QL + G C
Sbjct: 126 VKLHGNKDSICK-PCHMAQLASVCGSDGHTYSSVCKLEQQACLSSKQLAVRCEGPC 180
>gi|4759164 sparc/osteonectin, cwcv and kazal-like domains
proteoglycan 1 precursor [Homo sapiens]
Length = 439
Score = 51.6 bits (122), Expect = 1e-06
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 1/56 (1%)
Query: 90 CVAERKYTQEQAR-KEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGT 144
C E Q+ ++ K FIP CN++G Y QCH TG CWCV G ++G+
Sbjct: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCVDKYGNELAGS 368
Score = 43.1 bits (100), Expect = 5e-04
Identities = 19/46 (41%), Positives = 21/46 (45%)
Query: 227 CDQEHQSALEEAKQPKNDNVVIPECAHGGLYKPVQCHPSTGYCWCV 272
C E + +K IP C G YK QCH STG CWCV
Sbjct: 313 CQNEMNRIQKLSKGKSLLGAFIPRCNEEGYYKATQCHGSTGQCWCV 358
>gi|5453652 follistatin isoform FST317 precursor [Homo sapiens]
Length = 317
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 40 CSLDCAGSPQK-PLCASDGRTFLSRCEFQRAKCKD-PQLEIAYRGNCKDVSR---CVAER 94
C+ DC+ K P+C DG+T+ + C +A+CK+ P+LE+ Y+G CK R C
Sbjct: 118 CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSS 177
Query: 95 KYTQEQARKEFQQV---FIPE--------CNDDGTYSQVQCHSYTGYCWCVTPNGRPISG 143
+Q + PE C +DG CH C G G
Sbjct: 178 TCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEG 237
Query: 144 TAVAHKT 150
+ K+
Sbjct: 238 KCIKAKS 244
Score = 33.5 bits (75), Expect = 0.41
Identities = 14/36 (38%), Positives = 21/36 (58%), Gaps = 1/36 (2%)
Query: 50 KPLCASDGRTFLSRCEFQRAKCKD-PQLEIAYRGNC 84
+P+CASD T+ S C + A C LE+ + G+C
Sbjct: 281 EPVCASDNATYASECAMKEAACSSGVLLEVKHSGSC 316
>gi|7242222 follistatin isoform FST344 precursor [Homo sapiens]
Length = 344
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/127 (26%), Positives = 51/127 (40%), Gaps = 16/127 (12%)
Query: 40 CSLDCAGSPQK-PLCASDGRTFLSRCEFQRAKCKD-PQLEIAYRGNCKDVSR---CVAER 94
C+ DC+ K P+C DG+T+ + C +A+CK+ P+LE+ Y+G CK R C
Sbjct: 118 CAPDCSNITWKGPVCGLDGKTYRNECALLKARCKEQPELEVQYQGRCKKTCRDVFCPGSS 177
Query: 95 KYTQEQARKEFQQV---FIPE--------CNDDGTYSQVQCHSYTGYCWCVTPNGRPISG 143
+Q + PE C +DG CH C G G
Sbjct: 178 TCVVDQTNNAYCVTCNRICPEPASSEQYLCGNDGVTYSSACHLRKATCLLGRSIGLAYEG 237
Query: 144 TAVAHKT 150
+ K+
Sbjct: 238 KCIKAKS 244
Score = 39.3 bits (90), Expect = 0.008
Identities = 17/52 (32%), Positives = 28/52 (53%), Gaps = 1/52 (1%)
Query: 50 KPLCASDGRTFLSRCEFQRAKCKD-PQLEIAYRGNCKDVSRCVAERKYTQEQ 100
+P+CASD T+ S C + A C LE+ + G+C +S E + ++Q
Sbjct: 281 EPVCASDNATYASECAMKEAACSSGVLLEVKHSGSCNSISEDTEEEEEDEDQ 332
>gi|68448544 CD74 antigen isoform a [Homo sapiens]
Length = 296
Score = 49.3 bits (116), Expect = 7e-06
Identities = 17/36 (47%), Positives = 24/36 (66%)
Query: 109 FIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGT 144
F P+C+++G Y +QC+ GYCWCV PNG + T
Sbjct: 228 FRPKCDENGNYLPLQCYGSIGYCWCVFPNGTEVPNT 263
Score = 45.1 bits (105), Expect = 1e-04
Identities = 18/38 (47%), Positives = 23/38 (60%), Gaps = 1/38 (2%)
Query: 249 PECAHGGLYKPVQCHPSTGYCWCVLVDTGRPIPGTSTR 286
P+C G Y P+QC+ S GYCWCV G +P T +R
Sbjct: 230 PKCDENGNYLPLQCYGSIGYCWCVF-PNGTEVPNTRSR 266
>gi|5031701 follistatin-like 3 glycoprotein precursor [Homo sapiens]
Length = 263
Score = 48.9 bits (115), Expect = 9e-06
Identities = 20/49 (40%), Positives = 31/49 (63%), Gaps = 2/49 (4%)
Query: 39 DCSLDCAGSPQK-PLCASDGRTFLSRCEFQRAKCK-DPQLEIAYRGNCK 85
+C+ DC+G P + +C SDG T+ CE + A+C+ P L + YRG C+
Sbjct: 120 ECAPDCSGLPARLQVCGSDGATYRDECELRAARCRGHPDLSVMYRGRCR 168
>gi|62243068 insulin-like growth factor binding protein 3 isoform b
precursor [Homo sapiens]
Length = 291
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 22/153 (14%)
Query: 151 PRCPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAAAPALETQ----PQGDEEDIASRYPT 206
P PG+ +E R G S + S D L ++ +G +D + RY
Sbjct: 131 PPAPGNASESEEDRSA-GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKD-SQRYKV 188
Query: 207 LWTEQVKSRQNKTNKNSVSS----CDQEHQSALEEAK-----QPKNDNVVIPECAHGGLY 257
+ Q QN ++++ + C +E + L K P+ V IP C G Y
Sbjct: 189 DYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFY 246
Query: 258 KPVQCHPS----TGYCWCVLVDTGRPIPGTSTR 286
K QC PS G+CWCV G+P+PG +T+
Sbjct: 247 KKKQCRPSKGRKRGFCWCV-DKYGQPLPGYTTK 278
Score = 37.7 bits (86), Expect = 0.022
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 4/40 (10%)
Query: 108 VFIPECNDDGTYSQVQCHSYTG----YCWCVTPNGRPISG 143
V IP C+ G Y + QC G +CWCV G+P+ G
Sbjct: 235 VHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 274
>gi|62243248 insulin-like growth factor binding protein 3 isoform a
precursor [Homo sapiens]
Length = 297
Score = 48.1 bits (113), Expect = 2e-05
Identities = 43/153 (28%), Positives = 65/153 (42%), Gaps = 22/153 (14%)
Query: 151 PRCPGSVNEKLPQREGTGKTVSLQIFSVLNSDDAAAPALETQ----PQGDEEDIASRYPT 206
P PG+ +E R G S + S D L ++ +G +D + RY
Sbjct: 137 PPAPGNASESEEDRSA-GSVESPSVSSTHRVSDPKFHPLHSKIIIIKKGHAKD-SQRYKV 194
Query: 207 LWTEQVKSRQNKTNKNSVSS----CDQEHQSALEEAK-----QPKNDNVVIPECAHGGLY 257
+ Q QN ++++ + C +E + L K P+ V IP C G Y
Sbjct: 195 DYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLSPRG--VHIPNCDKKGFY 252
Query: 258 KPVQCHPS----TGYCWCVLVDTGRPIPGTSTR 286
K QC PS G+CWCV G+P+PG +T+
Sbjct: 253 KKKQCRPSKGRKRGFCWCV-DKYGQPLPGYTTK 284
Score = 38.1 bits (87), Expect = 0.017
Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 35/163 (21%)
Query: 11 LLAGLLPPVPAQKFSALTFLRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCE----- 65
L A LLP PA + ++D+ AGS + P +S R +
Sbjct: 123 LRAYLLPAPPAPGEPPAPGNASESEEDRS-----AGSVESPSVSSTHRVSDPKFHPLHSK 177
Query: 66 ---FQRAKCKDPQ-LEIAYRGNCKDVSRCVAERKYTQEQA--RKEFQQ------------ 107
++ KD Q ++ Y D +E K E R+E +
Sbjct: 178 IIIIKKGHAKDSQRYKVDYESQSTDTQNFSSESKRETEYGPCRREMEDTLNHLKFLNVLS 237
Query: 108 ---VFIPECNDDGTYSQVQCHSYTG----YCWCVTPNGRPISG 143
V IP C+ G Y + QC G +CWCV G+P+ G
Sbjct: 238 PRGVHIPNCDKKGFYKKKQCRPSKGRKRGFCWCVDKYGQPLPG 280
>gi|4504615 insulin-like growth factor binding protein 1 precursor
[Homo sapiens]
Length = 259
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/73 (32%), Positives = 35/73 (47%), Gaps = 5/73 (6%)
Query: 86 DVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHS----YTGYCWCVTP-NGRP 140
++ R V QE + +E + ++P CN +G Y QC + G CWCV P NG+
Sbjct: 179 ELYRVVESLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKR 238
Query: 141 ISGTAVAHKTPRC 153
I G+ P C
Sbjct: 239 IPGSPEIRGDPNC 251
Score = 38.5 bits (88), Expect = 0.013
Identities = 20/66 (30%), Positives = 29/66 (43%), Gaps = 7/66 (10%)
Query: 234 ALEEAKQPKNDNV---VIPECAHGGLYKPVQCHPS----TGYCWCVLVDTGRPIPGTSTR 286
+L +A++ + + +P C G Y QC S G CWCV G+ IPG+
Sbjct: 186 SLAKAQETSGEEISKFYLPNCNKNGFYHSRQCETSMDGEAGLCWCVYPWNGKRIPGSPEI 245
Query: 287 YEQPKC 292
P C
Sbjct: 246 RGDPNC 251
>gi|93141003 testican 3 isoform 1 [Homo sapiens]
Length = 433
Score = 47.4 bits (111), Expect = 3e-05
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 98 QEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAV 146
+ Q K+ +IP C++DG Y QCH G CWCV G + G+ +
Sbjct: 323 KRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 371
Score = 43.1 bits (100), Expect = 5e-04
Identities = 16/25 (64%), Positives = 16/25 (64%)
Query: 248 IPECAHGGLYKPVQCHPSTGYCWCV 272
IP C G YKP QCH S G CWCV
Sbjct: 335 IPLCDEDGYYKPTQCHGSVGQCWCV 359
>gi|93141001 testican 3 isoform 2 [Homo sapiens]
Length = 436
Score = 47.4 bits (111), Expect = 3e-05
Identities = 18/49 (36%), Positives = 26/49 (53%)
Query: 98 QEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISGTAV 146
+ Q K+ +IP C++DG Y QCH G CWCV G + G+ +
Sbjct: 326 KRQGVKKLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSRI 374
Score = 43.1 bits (100), Expect = 5e-04
Identities = 16/25 (64%), Positives = 16/25 (64%)
Query: 248 IPECAHGGLYKPVQCHPSTGYCWCV 272
IP C G YKP QCH S G CWCV
Sbjct: 338 IPLCDEDGYYKPTQCHGSVGQCWCV 362
>gi|4507171 secreted protein, acidic, cysteine-rich [Homo sapiens]
Length = 303
Score = 47.0 bits (110), Expect = 4e-05
Identities = 24/69 (34%), Positives = 38/69 (55%), Gaps = 4/69 (5%)
Query: 363 VHWYFKLLDKNS-SGDIGKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELM 421
VHW F LD++ G + E+ P + L + C +F E CD++NDK I++ E
Sbjct: 231 VHWQFGQLDQHPIDGYLSHTELAPLRAPLIPM---EHCTTRFFETCDLDNDKYIALDEWA 287
Query: 422 GCLGVAKED 430
GC G+ ++D
Sbjct: 288 GCFGIKQKD 296
Score = 33.1 bits (74), Expect = 0.54
Identities = 16/46 (34%), Positives = 24/46 (52%), Gaps = 6/46 (13%)
Query: 52 LCASDGRTFLSRCEFQRAKC------KDPQLEIAYRGNCKDVSRCV 91
+C++D +TF S C F KC K +L + Y G CK + C+
Sbjct: 111 VCSNDNKTFDSSCHFFATKCTLEGTKKGHKLHLDYIGPCKYIPPCL 156
>gi|12383051 transmembrane protein with EGF-like and two
follistatin-like domains 2 [Homo sapiens]
Length = 374
Score = 46.6 bits (109), Expect = 5e-05
Identities = 18/48 (37%), Positives = 32/48 (66%), Gaps = 1/48 (2%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNCKD 86
C++DC+ + PLCASDG+++ + C+ + A C K ++E+ G C+D
Sbjct: 182 CNIDCSQTNFNPLCASDGKSYDNACQIKEASCQKQEKIEVMSLGRCQD 229
Score = 29.6 bits (65), Expect = 5.9
Identities = 14/56 (25%), Positives = 27/56 (48%), Gaps = 2/56 (3%)
Query: 30 LRVDQDKDKDCSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCK-DPQLEIAYRGNC 84
LR+ C C + P+C S+G ++ + C ++A CK ++ + G+C
Sbjct: 81 LRIGDTVTCVCQFKC-NNDYVPVCGSNGESYQNECYLRQAACKQQSEILVVSEGSC 135
>gi|29568105 transmembrane protein with EGF-like and two
follistatin-like domains 1 [Homo sapiens]
Length = 380
Score = 46.2 bits (108), Expect = 6e-05
Identities = 19/48 (39%), Positives = 31/48 (64%), Gaps = 1/48 (2%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNCKD 86
C++DC+G P+CASDG ++ + C + A C K Q++I + G+C D
Sbjct: 190 CNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTD 237
Score = 31.6 bits (70), Expect = 1.6
Identities = 13/35 (37%), Positives = 21/35 (60%), Gaps = 1/35 (2%)
Query: 51 PLCASDGRTFLSRCEFQRAKCK-DPQLEIAYRGNC 84
P+C S+G T+ + C +RA CK ++ + RG C
Sbjct: 109 PVCGSNGDTYQNECFLRRAACKHQKEITVIARGPC 143
>gi|62243290 insulin-like growth factor binding protein 4 precursor
[Homo sapiens]
Length = 258
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/67 (38%), Positives = 31/67 (46%), Gaps = 10/67 (14%)
Query: 226 SCDQEHQSALEE--AKQPKNDN----VVIPECAHGGLYKPVQCHPS----TGYCWCVLVD 275
SC E ALE A Q + + IP C G + P QCHP+ G CWCV
Sbjct: 173 SCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCVDRK 232
Query: 276 TGRPIPG 282
TG +PG
Sbjct: 233 TGVKLPG 239
Score = 35.4 bits (80), Expect = 0.11
Identities = 16/59 (27%), Positives = 30/59 (50%), Gaps = 5/59 (8%)
Query: 81 RGNCK-DVSRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCH----SYTGYCWCV 134
+G+C+ ++ R + +Q + ++ + IP C+ +G + QCH G CWCV
Sbjct: 171 QGSCQSELHRALERLAASQSRTHEDLYIIPIPNCDRNGNFHPKQCHPALDGQRGKCWCV 229
>gi|54873613 agrin [Homo sapiens]
Length = 2045
Score = 43.5 bits (101), Expect = 4e-04
Identities = 17/47 (36%), Positives = 28/47 (59%), Gaps = 1/47 (2%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQ-LEIAYRGNCK 85
C C P P+C SDG T+ + CE ++A+C+ + L +A +G C+
Sbjct: 705 CDFSCQSVPGSPVCGSDGVTYSTECELKKARCESQRGLYVAAQGACR 751
Score = 37.4 bits (85), Expect = 0.029
Identities = 18/43 (41%), Positives = 24/43 (55%), Gaps = 1/43 (2%)
Query: 44 CAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNCK 85
C P P+C SDG T+ S CE + A C + Q+E A G C+
Sbjct: 623 CEHPPPGPVCGSDGVTYGSACELREAACLQQTQIEEARAGPCE 665
Score = 36.6 bits (83), Expect = 0.049
Identities = 35/132 (26%), Positives = 52/132 (39%), Gaps = 26/132 (19%)
Query: 40 CSLD---CAGSPQKPLCASDGRTFLSRCEFQRAKCKDPQ-LEIAYRGNCKDV-------- 87
CS D C G+ +P+CA DGRT+ S C Q+A+C+ + + ++G C
Sbjct: 414 CSCDRVTCDGA-YRPVCAQDGRTYDSDCWRQQAECRQQRAIPSKHQGPCDQAPSPCLGVQ 472
Query: 88 ----SRCVAERKYTQEQARKEFQQVFIPECNDDGTYSQVQCHSYTGYCWCVTPNGRPISG 143
+ C + + + ++ P C DG C C GR I
Sbjct: 473 CAFGATCAVKNGQAACECLQACSSLYDPVCGSDGVTYGSACELEATACTL----GREIQ- 527
Query: 144 TAVAHKTP--RC 153
VA K P RC
Sbjct: 528 --VARKGPCDRC 537
Score = 35.8 bits (81), Expect = 0.083
Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 1/52 (1%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNCKDVSRC 90
C S P+C SD T+ + CE QRA+C + ++ + RG C C
Sbjct: 197 CKKSPCPSVVAPVCGSDASTYSNECELQRAQCSQQRRIRLLSRGPCGSRDPC 248
Score = 32.3 bits (72), Expect = 0.92
Identities = 11/32 (34%), Positives = 16/32 (50%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKC 71
C C G+P+ +C SDG + C+ R C
Sbjct: 272 CPATCRGAPEGTVCGSDGADYPGECQLLRRAC 303
Score = 30.0 bits (66), Expect = 4.6
Identities = 16/47 (34%), Positives = 21/47 (44%), Gaps = 2/47 (4%)
Query: 40 CSLDCAGSPQKPLCASDGRTFLSRCEFQRAKCKDP-QLEIAYRGNCK 85
C +C Q P+C SDG T+ S C C L +A G C+
Sbjct: 555 CPSECVALAQ-PVCGSDGHTYPSECMLHVHACTHQISLHVASAGPCE 600
>gi|190194423 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 43.5 bits (101), Expect = 4e-04
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Query: 363 VHWYFKLLDKNSSGDI-GKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELM 421
VHW F LD++ + E+ P + L + C+ +F E CD N DK I+++E
Sbjct: 592 VHWQFSELDQHPMDRVLTHSELAPLRASLVPM---EHCITRFFEECDPNKDKHITLKEWG 648
Query: 422 GCLGVAKED 430
C G+ +ED
Sbjct: 649 HCFGIKEED 657
Score = 36.2 bits (82), Expect = 0.064
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 48 PQKPL---CASDGRTFLSRCEFQRAKC------KDPQLEIAYRGNCKDVSRC 90
P KPL C +D +T+ S C KC K QL++ Y G CK + C
Sbjct: 464 PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTC 515
>gi|190341024 SPARC-like 1 [Homo sapiens]
Length = 664
Score = 43.5 bits (101), Expect = 4e-04
Identities = 23/69 (33%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Query: 363 VHWYFKLLDKNSSGDI-GKKEIKPFKRFLRKKSKPKKCVKKFVEYCDVNNDKSISVQELM 421
VHW F LD++ + E+ P + L + C+ +F E CD N DK I+++E
Sbjct: 592 VHWQFSELDQHPMDRVLTHSELAPLRASLVPM---EHCITRFFEECDPNKDKHITLKEWG 648
Query: 422 GCLGVAKED 430
C G+ +ED
Sbjct: 649 HCFGIKEED 657
Score = 36.2 bits (82), Expect = 0.064
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 48 PQKPL---CASDGRTFLSRCEFQRAKC------KDPQLEIAYRGNCKDVSRC 90
P KPL C +D +T+ S C KC K QL++ Y G CK + C
Sbjct: 464 PTKPLDQVCGTDNQTYASSCHLFATKCRLEGTKKGHQLQLDYFGACKSIPTC 515
>gi|55925576 insulin-like growth factor binding protein 2, 36kDa
[Homo sapiens]
Length = 328
Score = 40.8 bits (94), Expect = 0.003
Identities = 22/60 (36%), Positives = 27/60 (45%), Gaps = 5/60 (8%)
Query: 110 IPECNDDGTYSQVQC----HSYTGYCWCVTPN-GRPISGTAVAHKTPRCPGSVNEKLPQR 164
IP C+ G Y+ QC + G CWCV PN G+ I G P C NE+ R
Sbjct: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPECHLFYNEQQEAR 320
Score = 40.0 bits (92), Expect = 0.004
Identities = 21/49 (42%), Positives = 24/49 (48%), Gaps = 4/49 (8%)
Query: 248 IPECAHGGLYKPVQCHPST----GYCWCVLVDTGRPIPGTSTRYEQPKC 292
IP C GLY QC S G CWCV +TG+ I G T P+C
Sbjct: 261 IPNCDKHGLYNLKQCKMSLNGQRGECWCVNPNTGKLIQGAPTIRGDPEC 309
>gi|11321593 insulin-like growth factor binding protein 6 [Homo
sapiens]
Length = 240
Score = 40.4 bits (93), Expect = 0.003
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
Query: 98 QEQARKEFQQVFIPECNDDGTYSQVQCHSYTGY----CWCVTPNGRPISGTAVAHKTPRC 153
Q + + Q +++P C+ G Y + QC S G CWCV G+ + G+ + + C
Sbjct: 175 QTEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCVDRMGKSLPGSPDGNGSSSC 234
Query: 154 P 154
P
Sbjct: 235 P 235
Score = 35.8 bits (81), Expect = 0.083
Identities = 26/111 (23%), Positives = 41/111 (36%), Gaps = 8/111 (7%)
Query: 180 NSDDAAAPALETQPQGDEEDIASRYPTLWTEQVKSRQNKTNKNSVSSCDQEHQSALEEAK 239
N ++ A +PQ R P T + + C + S L++ +
Sbjct: 116 NPKESKPQAGTARPQDVNRRDQQRNPGTSTTPSQPNSAGVQDTEMGPCRRHLDSVLQQLQ 175
Query: 240 QPKN---DNVVIPECAHGGLYKPVQCHPSTGY----CWCVLVDTGRPIPGT 283
+ +P C H G Y+ QC S G CWCV G+ +PG+
Sbjct: 176 TEVYRGAQTLYVPNCDHRGFYRKRQCRSSQGQRRGPCWCV-DRMGKSLPGS 225
>gi|5901956 follistatin-like 1 precursor [Homo sapiens]
Length = 308
Score = 39.3 bits (90), Expect = 0.008
Identities = 14/39 (35%), Positives = 27/39 (69%), Gaps = 1/39 (2%)
Query: 49 QKPLCASDGRTFLSRCEFQRAKC-KDPQLEIAYRGNCKD 86
++P+C S+G+T+L+ CE R C ++++ Y G+CK+
Sbjct: 62 KRPVCGSNGKTYLNHCELHRDACLTGSKIQVDYDGHCKE 100
>gi|149408146 TOX high mobility group box family member 2 isoform b
[Homo sapiens]
Length = 488
Score = 38.1 bits (87), Expect = 0.017
Identities = 32/126 (25%), Positives = 55/126 (43%), Gaps = 9/126 (7%)
Query: 338 AASDPSSSSGRLSEPDPSHTLEERVVHWYFKLL-DKNSSGDIGKKEIKPFKRFLRKKSKP 396
A S PS + + P PS + +E +FK+ +K S D GKK P K+ + ++P
Sbjct: 196 AHSSPSPPGSKSATPSPSSSTQEEESEVHFKISGEKRPSADPGKKAKNPKKKKKKDPNEP 255
Query: 397 KKCVKKFVEYCDVNNDKSISVQELMGCLGVAKE------DGKADTKKRHTP-RGHAESTS 449
+K V + + + +I Q G + D + +K+ +P +G +ST
Sbjct: 256 QKPVSAYALFFR-DTQAAIKGQNPSATFGDVSKIVASMWDSLGEEQKQSSPDQGETKSTQ 314
Query: 450 NRQPRK 455
P K
Sbjct: 315 ANPPAK 320
>gi|215983090 guanylate cyclase activator 1C [Homo sapiens]
Length = 209
Score = 37.0 bits (84), Expect = 0.037
Identities = 20/75 (26%), Positives = 39/75 (52%), Gaps = 7/75 (9%)
Query: 360 ERVVHWYFKLLDKNSSGDIGKKEIKPFKRFL-----RKKSKPKKCVKKFVEYCDVNNDKS 414
E+ + WYFKL D + +G I K E+ + ++ P++ + D+NND
Sbjct: 90 EQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGE 149
Query: 415 ISVQELMGCLGVAKE 429
++++E + G+AK+
Sbjct: 150 LTLEEFIN--GMAKD 162
>gi|10834982 insulin-like growth factor binding protein 5 [Homo
sapiens]
Length = 272
Score = 36.2 bits (82), Expect = 0.064
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 8/63 (12%)
Query: 227 CDQEHQSALEEAKQPKN---DNVVIPECAHGGLYKPVQCHPS----TGYCWCVLVDTGRP 279
C + +++L+E K V +P C G YK QC PS G CWCV G
Sbjct: 192 CRRHMEASLQELKASPRMVPRAVYLPNCDRKGFYKRKQCKPSRGRKRGICWCV-DKYGMK 250
Query: 280 IPG 282
+PG
Sbjct: 251 LPG 253
Score = 32.3 bits (72), Expect = 0.92
Identities = 14/40 (35%), Positives = 19/40 (47%), Gaps = 4/40 (10%)
Query: 108 VFIPECNDDGTYSQVQCH----SYTGYCWCVTPNGRPISG 143
V++P C+ G Y + QC G CWCV G + G
Sbjct: 214 VYLPNCDRKGFYKRKQCKPSRGRKRGICWCVDKYGMKLPG 253
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,209,337
Number of Sequences: 37866
Number of extensions: 1021496
Number of successful extensions: 3294
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 32
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 3133
Number of HSP's gapped (non-prelim): 181
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.