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Search of human proteins with 24307933
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|24307933 transcription factor EB [Homo sapiens]
(476 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|24307933 transcription factor EB [Homo sapiens] 955 0.0
gi|38156705 microphthalmia-associated transcription factor isofo... 357 2e-98
gi|38156703 microphthalmia-associated transcription factor isofo... 357 2e-98
gi|38156701 microphthalmia-associated transcription factor isofo... 357 2e-98
gi|38156699 microphthalmia-associated transcription factor isofo... 357 2e-98
gi|8659574 transcription factor E3 [Homo sapiens] 345 7e-95
gi|38156697 microphthalmia-associated transcription factor isofo... 309 3e-84
gi|4557755 microphthalmia-associated transcription factor isofor... 303 3e-82
gi|6912702 transcription factor EC isoform a [Homo sapiens] 250 2e-66
gi|64762402 transcription factor EC isoform b [Homo sapiens] 237 2e-62
gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens] 59 1e-08
gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens] 59 1e-08
gi|33286444 mastermind-like 2 [Homo sapiens] 53 7e-07
gi|27477113 sterol regulatory element-binding transcription fact... 51 3e-06
gi|110347429 mediator complex subunit 12 [Homo sapiens] 49 1e-05
gi|9945318 MAX binding protein [Homo sapiens] 48 2e-05
gi|52630419 sterol regulatory element binding transcription fact... 48 2e-05
gi|22547195 sterol regulatory element binding transcription fact... 48 2e-05
gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens] 48 2e-05
gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens] 48 2e-05
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 47 3e-05
gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens] 47 3e-05
gi|189491748 ataxin 1 [Homo sapiens] 47 3e-05
gi|51479158 ataxin 1 [Homo sapiens] 47 3e-05
gi|226246533 TOX high mobility group box family member 3 isoform... 47 5e-05
gi|226054295 TOX high mobility group box family member 3 isoform... 47 5e-05
gi|17017963 forkhead box P2 isoform I [Homo sapiens] 46 6e-05
gi|22538413 forkhead box P2 isoform III [Homo sapiens] 46 6e-05
gi|149999352 forkhead box P2 isoform II [Homo sapiens] 46 6e-05
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 45 1e-04
>gi|24307933 transcription factor EB [Homo sapiens]
Length = 476
Score = 955 bits (2468), Expect = 0.0
Identities = 476/476 (100%), Positives = 476/476 (100%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQ 60
MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQ
Sbjct: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQ 60
Query: 61 SPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPA 120
SPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPA
Sbjct: 61 SPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPA 120
Query: 121 ASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQM 180
ASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQM
Sbjct: 121 ASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRLDDVLGYINPEMQM 180
Query: 181 PNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNH 240
PNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNH
Sbjct: 181 PNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNH 240
Query: 241 NLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELEN 300
NLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELEN
Sbjct: 241 NLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELEN 300
Query: 301 HSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEAL 360
HSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEAL
Sbjct: 301 HSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEAL 360
Query: 361 MLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPG 420
MLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPG
Sbjct: 361 MLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPG 420
Query: 421 HGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL 476
HGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL
Sbjct: 421 HGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL 476
>gi|38156705 microphthalmia-associated transcription factor isoform
6 [Homo sapiens]
Length = 495
Score = 357 bits (915), Expect = 2e-98
Identities = 230/509 (45%), Positives = 300/509 (58%), Gaps = 83/509 (16%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINT--PVH 58
M SRI LR QLMREQ Q++E+RE+ Q+ +MQQ+ Q TPAIN P
Sbjct: 28 MTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ-------TPAINVSVPTT 80
Query: 59 FQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPP 118
S VP EVLKVQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P
Sbjct: 81 LPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------P 134
Query: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERE---------------------- 156
PG HV+ G+SAPNSPMAML + SN E+E
Sbjct: 135 CPNQPG---DHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHS 191
Query: 157 ------LDDVIDNIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLV 205
+DDVID+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L
Sbjct: 192 RASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT 251
Query: 206 GVTSSSCPADLTQ-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPK 264
S+SCPA+L KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK
Sbjct: 252 --ISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK 309
Query: 265 ANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQAR 324
+ND D+RWNKGTILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR
Sbjct: 310 SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQAR 369
Query: 325 VHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLP 384
HGL +G+ +L +++KQE P E + L L A L
Sbjct: 370 AHGLSLIPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCT 414
Query: 385 TQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLP 444
T + F+++L G E Y P G L+ +L+DD+L P
Sbjct: 415 TTLDLTDGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSP 461
Query: 445 L-ASDPLLSTMSPEASKASSRRSSFSMEE 472
+ +DPLLS++SP ASK SSRRSS SMEE
Sbjct: 462 VGVTDPLLSSVSPGASKTSSRRSSMSMEE 490
>gi|38156703 microphthalmia-associated transcription factor isoform
2 [Homo sapiens]
Length = 504
Score = 357 bits (915), Expect = 2e-98
Identities = 230/509 (45%), Positives = 300/509 (58%), Gaps = 83/509 (16%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINT--PVH 58
M SRI LR QLMREQ Q++E+RE+ Q+ +MQQ+ Q TPAIN P
Sbjct: 37 MTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ-------TPAINVSVPTT 89
Query: 59 FQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPP 118
S VP EVLKVQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P
Sbjct: 90 LPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------P 143
Query: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERE---------------------- 156
PG HV+ G+SAPNSPMAML + SN E+E
Sbjct: 144 CPNQPG---DHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHS 200
Query: 157 ------LDDVIDNIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLV 205
+DDVID+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L
Sbjct: 201 RASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT 260
Query: 206 GVTSSSCPADLTQ-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPK 264
S+SCPA+L KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK
Sbjct: 261 --ISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK 318
Query: 265 ANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQAR 324
+ND D+RWNKGTILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR
Sbjct: 319 SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQAR 378
Query: 325 VHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLP 384
HGL +G+ +L +++KQE P E + L L A L
Sbjct: 379 AHGLSLIPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCT 423
Query: 385 TQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLP 444
T + F+++L G E Y P G L+ +L+DD+L P
Sbjct: 424 TTLDLTDGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSP 470
Query: 445 L-ASDPLLSTMSPEASKASSRRSSFSMEE 472
+ +DPLLS++SP ASK SSRRSS SMEE
Sbjct: 471 VGVTDPLLSSVSPGASKTSSRRSSMSMEE 499
>gi|38156701 microphthalmia-associated transcription factor isoform
3 [Homo sapiens]
Length = 519
Score = 357 bits (915), Expect = 2e-98
Identities = 230/509 (45%), Positives = 300/509 (58%), Gaps = 83/509 (16%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINT--PVH 58
M SRI LR QLMREQ Q++E+RE+ Q+ +MQQ+ Q TPAIN P
Sbjct: 52 MTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ-------TPAINVSVPTT 104
Query: 59 FQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPP 118
S VP EVLKVQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P
Sbjct: 105 LPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------P 158
Query: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERE---------------------- 156
PG HV+ G+SAPNSPMAML + SN E+E
Sbjct: 159 CPNQPG---DHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHS 215
Query: 157 ------LDDVIDNIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLV 205
+DDVID+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L
Sbjct: 216 RASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT 275
Query: 206 GVTSSSCPADLTQ-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPK 264
S+SCPA+L KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK
Sbjct: 276 --ISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK 333
Query: 265 ANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQAR 324
+ND D+RWNKGTILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR
Sbjct: 334 SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQAR 393
Query: 325 VHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLP 384
HGL +G+ +L +++KQE P E + L L A L
Sbjct: 394 AHGLSLIPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCT 438
Query: 385 TQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLP 444
T + F+++L G E Y P G L+ +L+DD+L P
Sbjct: 439 TTLDLTDGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSP 485
Query: 445 L-ASDPLLSTMSPEASKASSRRSSFSMEE 472
+ +DPLLS++SP ASK SSRRSS SMEE
Sbjct: 486 VGVTDPLLSSVSPGASKTSSRRSSMSMEE 514
>gi|38156699 microphthalmia-associated transcription factor isoform
1 [Homo sapiens]
Length = 520
Score = 357 bits (915), Expect = 2e-98
Identities = 230/509 (45%), Positives = 300/509 (58%), Gaps = 83/509 (16%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINT--PVH 58
M SRI LR QLMREQ Q++E+RE+ Q+ +MQQ+ Q TPAIN P
Sbjct: 53 MTSRILLRQQLMREQMQEQERREQQQKLQAAQFMQQRVPVSQ-------TPAINVSVPTT 105
Query: 59 FQSPPPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPP 118
S VP EVLKVQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P
Sbjct: 106 LPSATQVPMEVLKVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------P 159
Query: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERE---------------------- 156
PG HV+ G+SAPNSPMAML + SN E+E
Sbjct: 160 CPNQPG---DHVMPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHS 216
Query: 157 ------LDDVIDNIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLV 205
+DDVID+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L
Sbjct: 217 RASCMQMDDVIDDIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT 276
Query: 206 GVTSSSCPADLTQ-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPK 264
S+SCPA+L KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK
Sbjct: 277 --ISNSCPANLPNIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPK 334
Query: 265 ANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQAR 324
+ND D+RWNKGTILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR
Sbjct: 335 SNDPDMRWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQAR 394
Query: 325 VHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLP 384
HGL +G+ +L +++KQE P E + L L A L
Sbjct: 395 AHGLSLIPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCT 439
Query: 385 TQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLP 444
T + F+++L G E Y P G L+ +L+DD+L P
Sbjct: 440 TTLDLTDGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSP 486
Query: 445 L-ASDPLLSTMSPEASKASSRRSSFSMEE 472
+ +DPLLS++SP ASK SSRRSS SMEE
Sbjct: 487 VGVTDPLLSSVSPGASKTSSRRSSMSMEE 515
>gi|8659574 transcription factor E3 [Homo sapiens]
Length = 575
Score = 345 bits (884), Expect = 7e-95
Identities = 226/499 (45%), Positives = 294/499 (58%), Gaps = 64/499 (12%)
Query: 2 ASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPV---- 57
+SR+ LR QLMR QAQ++E+RER +Q A + P +PAI+
Sbjct: 111 SSRVLLRQQLMRAQAQEQERRERREQAAAAPFPSP----------APASPAISVVGVSAG 160
Query: 58 -HFQSPPP---VPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQG 113
H S PP VP EVLKVQ++LENPT YHLQQ++ Q+V++YLS T G K A+
Sbjct: 161 GHTLSRPPPAQVPREVLKVQTHLENPTRYHLQQARRQQVKQYLSTTLGPKLASQAL---- 216
Query: 114 SPKPPPAAS---PGVRAGHVLSSSAGNSAPNSPMAMLHIGSNPERELDDVIDNIMRL--- 167
+P P PA++ P A H + SAPNSPMA+L IGS+ E+E+DDVID I+ L
Sbjct: 217 TPPPGPASAQPLPAPEAAHTTGPTG--SAPNSPMALLTIGSSSEKEIDDVIDEIISLESS 274
Query: 168 --DDVLGYI---NPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQ-KRE 221
D++L Y+ +Q+P+TLP+S + L+VYSS T ++ S+SCPA+L KRE
Sbjct: 275 YNDEMLSYLPGGTTGLQLPSTLPVSGNLLDVYSSQGVATPAIT--VSNSCPAELPNIKRE 332
Query: 222 LTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKAS 281
+++ E++AL KERQKKDNHNLIERRRRFNINDRIKELG LIPK++D ++RWNKGTILKAS
Sbjct: 333 ISETEAKALLKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSSDPEMRWNKGTILKAS 392
Query: 282 VDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGM----- 336
VDYIR++QK+ Q+S++LE+ R LE N+ L LRIQELE+QA++HGLP G+
Sbjct: 393 VDYIRKLQKEQQRSKDLESRQRSLEQANRSLQLRIQELELQAQIHGLPVPPTPGLLSLAT 452
Query: 337 NMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDF 396
A + + + ++ E PG A P PP P P HL
Sbjct: 453 TSASDSLKPEQLDIEEEGRPGAATFHVGGGPAQNAPHQQPPAPPSDALLDLHFPSDHLGD 512
Query: 397 SHSLSFGGRED---EGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLST 453
G ED E G L+ G SP L ASDPLLS+
Sbjct: 513 LGDPFHLGLEDILMEEEEGVVGGLSGGALSP------------------LRAASDPLLSS 554
Query: 454 MSPEASKASSRRSSFSMEE 472
+SP SKASSRRSSFSMEE
Sbjct: 555 VSPAVSKASSRRSSFSMEE 573
>gi|38156697 microphthalmia-associated transcription factor isoform
5 [Homo sapiens]
Length = 413
Score = 309 bits (792), Expect = 3e-84
Identities = 196/437 (44%), Positives = 260/437 (59%), Gaps = 74/437 (16%)
Query: 71 KVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHV 130
+VQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P PG HV
Sbjct: 11 QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------PCPNQPG---DHV 61
Query: 131 LSSSAGNSAPNSPMAMLHIGSNPERE----------------------------LDDVID 162
+ G+SAPNSPMAML + SN E+E +DDVID
Sbjct: 62 MPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVID 121
Query: 163 NIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLT 217
+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L S+SCPA+L
Sbjct: 122 DIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT--ISNSCPANLP 179
Query: 218 Q-KRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGT 276
KRELT++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK+ND D+RWNKGT
Sbjct: 180 NIKRELTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDMRWNKGT 239
Query: 277 ILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGM 336
ILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR HGL +G+
Sbjct: 240 ILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSLIPSTGL 299
Query: 337 NMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDF 396
+L +++KQE P E + L L A L T + F
Sbjct: 300 CSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCTTTLDLTDGTITF 344
Query: 397 SHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPL-ASDPLLSTMS 455
+++L G E Y P G L+ +L+DD+L P+ +DPLLS++S
Sbjct: 345 NNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSPVGVTDPLLSSVS 391
Query: 456 PEASKASSRRSSFSMEE 472
P ASK SSRRSS SMEE
Sbjct: 392 PGASKTSSRRSSMSMEE 408
>gi|4557755 microphthalmia-associated transcription factor isoform 4
[Homo sapiens]
Length = 419
Score = 303 bits (775), Expect = 3e-82
Identities = 196/443 (44%), Positives = 260/443 (58%), Gaps = 80/443 (18%)
Query: 71 KVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHV 130
+VQ++LENPT YH+QQ+Q Q+V++YLS T NK A + P PG HV
Sbjct: 11 QVQTHLENPTKYHIQQAQRQQVKQYLSTTLANKHANQVLSL------PCPNQPG---DHV 61
Query: 131 LSSSAGNSAPNSPMAMLHIGSNPERE----------------------------LDDVID 162
+ G+SAPNSPMAML + SN E+E +DDVID
Sbjct: 62 MPPVPGSSAPNSPMAMLTLNSNCEKEGFYKFEEQNRAESECPGMNTHSRASCMQMDDVID 121
Query: 163 NIMRLD-----DVLGYINPEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLT 217
+I+ L+ ++LG ++P +QM NTLP+S + +++Y + L S+SCPA+L
Sbjct: 122 DIISLESSYNEEILGLMDPALQMANTLPVSGNLIDLYGNQGLPPPGLT--ISNSCPANLP 179
Query: 218 Q-KRELT------DAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDV 270
KRELT ++E+RALAKERQKKDNHNLIERRRRFNINDRIKELG LIPK+ND D+
Sbjct: 180 NIKRELTACIFPTESEARALAKERQKKDNHNLIERRRRFNINDRIKELGTLIPKSNDPDM 239
Query: 271 RWNKGTILKASVDYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELEMQARVHGLPT 330
RWNKGTILKASVDYIR++Q++ Q+++ELEN ++LE N+ L LRIQELEMQAR HGL
Sbjct: 240 RWNKGTILKASVDYIRKLQREQQRAKELENRQKKLEHANRHLLLRIQELEMQARAHGLSL 299
Query: 331 TSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSP 390
+G+ +L +++KQE P E + L L A L T
Sbjct: 300 IPSTGLCSPDLVNRIIKQE-PVLENCSQDL--------------LQHHADLTCTTTLDLT 344
Query: 391 FHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLDLMLLDDSLLPL-ASDP 449
+ F+++L G E Y P G L+ +L+DD+L P+ +DP
Sbjct: 345 DGTITFNNNLGTG---TEANQAYSVPTKMG----------SKLEDILMDDTLSPVGVTDP 391
Query: 450 LLSTMSPEASKASSRRSSFSMEE 472
LLS++SP ASK SSRRSS SMEE
Sbjct: 392 LLSSVSPGASKTSSRRSSMSMEE 414
>gi|6912702 transcription factor EC isoform a [Homo sapiens]
Length = 347
Score = 250 bits (638), Expect = 2e-66
Identities = 155/361 (42%), Positives = 209/361 (57%), Gaps = 36/361 (9%)
Query: 119 PAASPGVRAGHVLSSSAGNSAPNSPMAMLHIGS---NPERELDDVIDNIMRLDDVLGYIN 175
P+ P V+ H S N +L IG N + ++DVI++I+ ++
Sbjct: 20 PSGGPLVQHAHTTLDSDAGLTENPLTKLLAIGKEDDNAQWHMEDVIEDIIGMESSFKEEG 79
Query: 176 PEMQMPNTLPLSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQ 235
+ + LS S L+VYS + ++ +G+TS+SCP+ L KRE+T+ ++RALAKERQ
Sbjct: 80 ADSPLLMQRTLSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQ 139
Query: 236 KKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKS 295
KKDNHNLIERRRR+NIN RIKELG LIPK+ND D+RWNKGTILKASV+YI+ +QK+ Q++
Sbjct: 140 KKDNHNLIERRRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRA 199
Query: 296 RELENHSRRLEMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEG 355
RELE+ ++LE N++L LRIQELE+QAR HGLPT + G +L V KQ+ E+
Sbjct: 200 RELEHRQKKLEQANRRLLLRIQELEIQARTHGLPTLASLG--TVDLGAHVTKQQSHPEQN 257
Query: 356 PGEALMLGAEVPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPE 415
+ P P L QA + P S F L FS +L
Sbjct: 258 SVDYCQ--QLTVSQGPSPELCDQA--IAFSDPLSYFTDLSFSAALK-------------- 299
Query: 416 PLAPGHGSPFPSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDV 475
++ LD MLLDD++ P +DPLLS SP SK SSRRSSFS ++GD
Sbjct: 300 -------------EEQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDE 346
Query: 476 L 476
L
Sbjct: 347 L 347
>gi|64762402 transcription factor EC isoform b [Homo sapiens]
Length = 318
Score = 237 bits (605), Expect = 2e-62
Identities = 141/291 (48%), Positives = 182/291 (62%), Gaps = 33/291 (11%)
Query: 186 LSSSHLNVYSSDPQVTASLVGVTSSSCPADLTQKRELTDAESRALAKERQKKDNHNLIER 245
LS S L+VYS + ++ +G+TS+SCP+ L KRE+T+ ++RALAKERQKKDNHNLIER
Sbjct: 61 LSGSILDVYSGEQGISPINMGLTSASCPSSLPMKREITETDTRALAKERQKKDNHNLIER 120
Query: 246 RRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKDLQKSRELENHSRRL 305
RRR+NIN RIKELG LIPK+ND D+RWNKGTILKASV+YI+ +QK+ Q++RELE+ ++L
Sbjct: 121 RRRYNINYRIKELGTLIPKSNDPDMRWNKGTILKASVEYIKWLQKEQQRARELEHRQKKL 180
Query: 306 EMTNKQLWLRIQELEMQARVHGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAE 365
E N++L LRIQELE+QAR HGLPT + G +L V KQ+ E+ +
Sbjct: 181 EQANRRLLLRIQELEIQARTHGLPTLASLG--TVDLGAHVTKQQSHPEQNSVDYCQ--QL 236
Query: 366 VPDPEPLPALPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPF 425
P P L QA + P S F L FS +L
Sbjct: 237 TVSQGPSPELCDQA--IAFSDPLSYFTDLSFSAALK------------------------ 270
Query: 426 PSLSKKDLDLMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL 476
++ LD MLLDD++ P +DPLLS SP SK SSRRSSFS ++GD L
Sbjct: 271 ---EEQRLDGMLLDDTISPFGTDPLLSATSPAVSKESSRRSSFSSDDGDEL 318
>gi|46877105 upstream stimulatory factor 2 isoform 2 [Homo sapiens]
Length = 279
Score = 58.5 bits (140), Expect = 1e-08
Identities = 32/91 (35%), Positives = 56/91 (61%), Gaps = 2/91 (2%)
Query: 232 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRW--NKGTILKASVDYIRRMQ 289
++ +++ HN +ERRRR IN+ I +L +IP N + + +KG IL + DYIR ++
Sbjct: 165 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELR 224
Query: 290 KDLQKSRELENHSRRLEMTNKQLWLRIQELE 320
+ Q+ +E + RL+M N+ L +I+EL+
Sbjct: 225 QTNQRMQETFKEAERLQMDNELLRQQIEELK 255
>gi|4507847 upstream stimulatory factor 2 isoform 1 [Homo sapiens]
Length = 346
Score = 58.5 bits (140), Expect = 1e-08
Identities = 32/91 (35%), Positives = 56/91 (61%), Gaps = 2/91 (2%)
Query: 232 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRW--NKGTILKASVDYIRRMQ 289
++ +++ HN +ERRRR IN+ I +L +IP N + + +KG IL + DYIR ++
Sbjct: 232 RDERRRAQHNEVERRRRDKINNWIVQLSKIIPDCNADNSKTGASKGGILSKACDYIRELR 291
Query: 290 KDLQKSRELENHSRRLEMTNKQLWLRIQELE 320
+ Q+ +E + RL+M N+ L +I+EL+
Sbjct: 292 QTNQRMQETFKEAERLQMDNELLRQQIEELK 322
>gi|33286444 mastermind-like 2 [Homo sapiens]
Length = 1156
Score = 52.8 bits (125), Expect = 7e-07
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 15/121 (12%)
Query: 18 QEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYLE 77
Q++Q+++ QQQ QQQQQQQQQQ P ++ + +SP P+ ++L +Q
Sbjct: 639 QQQQQQQQQQQQQQQQQQQQQQQQQQQPSSQPAQSLPSQPLLRSPLPLQQKLL-LQQMQN 697
Query: 78 NPTS---YHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASPGVRAGHVLSSS 134
P + Y + Q Q Q + + G SP P P ++P +G++ S
Sbjct: 698 QPIAGMGYQVSQQQRQDQHSVVGQNTG-----------PSPSPNPCSNPNTGSGYMNSQQ 746
Query: 135 A 135
+
Sbjct: 747 S 747
Score = 46.2 bits (108), Expect = 6e-05
Identities = 31/107 (28%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 17 QQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKVQSYL 76
QQ++Q+++ QQQ QQQQQQQQQQ +I+ Q + + + Q
Sbjct: 588 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQSSISAQQQQQQQSSISAQQQQQQQQQ 647
Query: 77 ENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAASP 123
+ QQ Q Q+ ++ S+ PAQ P P SP
Sbjct: 648 QQQQQQQQQQQQQQQQQQPSSQ-----------PAQSLPSQPLLRSP 683
Score = 30.8 bits (68), Expect = 2.8
Identities = 12/16 (75%), Positives = 15/16 (93%)
Query: 29 AVMHYMQQQQQQQQQQ 44
+++HY QQQQQQQQQQ
Sbjct: 582 SLLHYTQQQQQQQQQQ 597
>gi|27477113 sterol regulatory element-binding transcription factor
2 [Homo sapiens]
Length = 1141
Score = 50.8 bits (120), Expect = 3e-06
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 27/161 (16%)
Query: 232 KERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVDYIRRMQKD 291
KE +++ HN+IE+R R +IND+I EL L+ D + +K +L+ ++DYI+ +Q+
Sbjct: 327 KEGERRTTHNIIEKRYRSSINDKIIELKDLV---MGTDAKMHKSGVLRKAIDYIKYLQQV 383
Query: 292 LQKSRE------LENHSRRL-------EMTNKQLWLRIQELEMQARVHGLPTTSPSGMNM 338
K R+ L N +L + + ++ L+I++ + P S SG +
Sbjct: 384 NHKLRQENMVLKLANQKNKLLKGIDLGSLVDNEVDLKIEDFNQNVLLMS-PPASDSG-SQ 441
Query: 339 AELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPALPPQA 379
A + + E PG L+ A+V D P PP A
Sbjct: 442 AGFSPYSIDSE------PGSPLLDDAKVKDE---PDSPPVA 473
>gi|110347429 mediator complex subunit 12 [Homo sapiens]
Length = 2177
Score = 48.9 bits (115), Expect = 1e-05
Identities = 24/55 (43%), Positives = 34/55 (61%), Gaps = 2/55 (3%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQ--QQQQQLGGPPTPAINTPVHFQ 60
+ Q++R+Q QQ++Q+++ QQQ QQQQQ QQQQQ PP P + FQ
Sbjct: 2084 QQQILRQQQQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQ 2138
Score = 38.1 bits (87), Expect = 0.018
Identities = 17/37 (45%), Positives = 24/37 (64%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q ++Q QQ+ + QQQ ++ QQQQQQQQQQ
Sbjct: 2065 QQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQ 2101
Score = 38.1 bits (87), Expect = 0.018
Identities = 18/37 (48%), Positives = 24/37 (64%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q ++Q QQ R++ QQQ + QQQQQQQQQQ
Sbjct: 2066 QQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQQQ 2102
Score = 37.4 bits (85), Expect = 0.030
Identities = 28/109 (25%), Positives = 48/109 (44%), Gaps = 20/109 (18%)
Query: 11 LMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVL 70
++ EQ QQ++Q+++ QQQ QQQQQQQQQQ + ++L
Sbjct: 2047 ILPEQQQQQQQQQQQQQQ------QQQQQQQQQQ------------QQYHIRQQQQQQIL 2088
Query: 71 KVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPP 119
+ Q + QQ Q Q+ ++ + + + +P Q P+ P
Sbjct: 2089 RQQQ--QQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQP 2135
Score = 37.4 bits (85), Expect = 0.030
Identities = 16/37 (43%), Positives = 26/37 (70%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q ++Q QQ++Q+ ++QQ ++QQQQQQQQQ
Sbjct: 2062 QQQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQ 2098
Score = 37.0 bits (84), Expect = 0.039
Identities = 18/37 (48%), Positives = 24/37 (64%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q ++Q QQ++ R QQQ + QQQQQQQQQQ
Sbjct: 2064 QQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQQ 2100
Score = 36.6 bits (83), Expect = 0.051
Identities = 17/40 (42%), Positives = 29/40 (72%), Gaps = 3/40 (7%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQ---QQQ 44
+ Q ++Q QQ++Q+++ QQQ ++++QQQQQQ QQQ
Sbjct: 2053 QQQQQQQQQQQQQQQQQQQQQQQQYHIRQQQQQQILRQQQ 2092
Score = 35.8 bits (81), Expect = 0.087
Identities = 18/37 (48%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q ++Q QQ++Q QQQ QQQQQQQQQQ
Sbjct: 2063 QQQQQQQQQQQQQQYHIRQQQQQQILRQQQQQQQQQQ 2099
Score = 30.0 bits (66), Expect = 4.8
Identities = 18/57 (31%), Positives = 26/57 (45%), Gaps = 20/57 (35%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQ--------------------QQQQQ 44
+ Q ++Q QQ++Q+++ QQQ H QQQQQ Q QQQ
Sbjct: 2092 QQQQQQQQQQQQQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQGLQQTQQQ 2148
Score = 30.0 bits (66), Expect = 4.8
Identities = 14/39 (35%), Positives = 23/39 (58%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLG 46
+ Q ++Q QQ++ +++ QQQA Q Q Q Q Q+ G
Sbjct: 2103 QQQQQQQQQQQQQHQQQQQQQAAPPQPQPQSQPQFQRQG 2141
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 48.1 bits (113), Expect = 2e-05
Identities = 42/189 (22%), Positives = 85/189 (44%), Gaps = 15/189 (7%)
Query: 216 LTQKRELTDAESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKG 275
L E+ +E + ++ HN +E+ RR ++ + + L IP + D + +
Sbjct: 201 LAPAEEVKSSEQKKRPGGIGTREVHNKLEKNRRAHLKECFETLKRNIPNVD--DKKTSNL 258
Query: 276 TILKASVDYIRRM-QKDLQKSRELENHSRRLEMTNKQL---------WLRIQELEMQARV 325
++L+ ++ YI+ + +K+ + E+E +R T ++L W+ + E++ R
Sbjct: 259 SVLRTALRYIQSLKRKEKEYEHEMERLAREKIATQQRLAELKHELSQWMDVLEIDRVLRQ 318
Query: 326 HGLPTTSPSGMNMAELAQQVVKQELPSEEGPGEALMLGAEVPDPEPLPA-LPPQAPLPLP 384
G P + + A + + +++ E+ G + P PE L + LPP + P P
Sbjct: 319 TGQPEDDQASTSTASEGEDNIDEDM-EEDRAGLGPPKLSHRPQPELLKSTLPPPSTTPAP 377
Query: 385 TQPPSPFHH 393
PP P H
Sbjct: 378 L-PPHPHPH 385
Score = 30.4 bits (67), Expect = 3.7
Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 25/132 (18%)
Query: 34 MQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPGEVLKV----QSYLENPTSYHLQQSQH 89
+QQQQ QQ+ L PP P Q+ P P ++ + + + + H Q
Sbjct: 398 VQQQQPQQKTPLPAPPPP---PAAPAQTLVPAPAHLVATAGGGSTVIAHTATTHASVIQ- 453
Query: 90 QKVREYLSETYGNKFAAHISPAQGSP--KPPPAASPGVRAGHVLSSSA--------GNSA 139
++ + G K AHI+P+ SP + PA P GH+ A G+
Sbjct: 454 --TVNHVLQGPGGKHIAHIAPSAPSPAVQLAPATPP---IGHITVHPATLNHVAHLGSQL 508
Query: 140 P--NSPMAMLHI 149
P P+A+ HI
Sbjct: 509 PLYPQPVAVSHI 520
>gi|52630419 sterol regulatory element binding transcription factor
1 isoform a [Homo sapiens]
Length = 1177
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/81 (38%), Positives = 50/81 (61%), Gaps = 5/81 (6%)
Query: 225 AESRALAKER-QKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVD 283
+++ A A+ R +K+ HN IE+R R +IND+I EL L+ + + NK +L+ ++D
Sbjct: 342 SKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVV---GTEAKLNKSAVLRKAID 398
Query: 284 YIRRMQKDLQKSRELENHSRR 304
YIR +Q QK ++ EN S R
Sbjct: 399 YIRFLQHSNQKLKQ-ENLSLR 418
Score = 29.3 bits (64), Expect = 8.2
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 329 PTTSPSGMNMAELAQQVVKQ--ELPS-EEGPG---EALMLGA-EVPDPEPLPA--LPPQA 379
P +PS ++ + A +K +P+ GPG E++ L + P P+PLP LP
Sbjct: 120 PQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSF 179
Query: 380 PLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPG 420
P P P Q S + GG PPG + PG
Sbjct: 180 PAPAPPQFSST---PVLGYPSPPGGFSTGSPPGNTQQPLPG 217
>gi|22547195 sterol regulatory element binding transcription factor
1 isoform b [Homo sapiens]
Length = 1147
Score = 47.8 bits (112), Expect = 2e-05
Identities = 31/81 (38%), Positives = 50/81 (61%), Gaps = 5/81 (6%)
Query: 225 AESRALAKER-QKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVRWNKGTILKASVD 283
+++ A A+ R +K+ HN IE+R R +IND+I EL L+ + + NK +L+ ++D
Sbjct: 312 SKAPASAQSRGEKRTAHNAIEKRYRSSINDKIIELKDLVV---GTEAKLNKSAVLRKAID 368
Query: 284 YIRRMQKDLQKSRELENHSRR 304
YIR +Q QK ++ EN S R
Sbjct: 369 YIRFLQHSNQKLKQ-ENLSLR 388
Score = 29.3 bits (64), Expect = 8.2
Identities = 30/101 (29%), Positives = 43/101 (42%), Gaps = 12/101 (11%)
Query: 329 PTTSPSGMNMAELAQQVVKQ--ELPS-EEGPG---EALMLGA-EVPDPEPLPA--LPPQA 379
P +PS ++ + A +K +P+ GPG E++ L + P P+PLP LP
Sbjct: 90 PQAAPSPLSPPQPAPTPLKMYPSMPAFSPGPGIKEESVPLSILQTPTPQPLPGALLPQSF 149
Query: 380 PLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPG 420
P P P Q S + GG PPG + PG
Sbjct: 150 PAPAPPQFSST---PVLGYPSPPGGFSTGSPPGNTQQPLPG 187
>gi|6005934 upstream stimulatory factor 1 isoform 1 [Homo sapiens]
Length = 310
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 9/122 (7%)
Query: 225 AESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVR--WNKGTILKASV 282
+E+ ++ +++ HN +ERRRR IN+ I +L +IP + + +KG IL +
Sbjct: 189 SEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKAC 248
Query: 283 DYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELE-------MQARVHGLPTTSPSG 335
DYI+ +++ + E +L++ N L ++++L+ Q R HGL +
Sbjct: 249 DYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKND 308
Query: 336 MN 337
N
Sbjct: 309 SN 310
>gi|46877102 upstream stimulatory factor 1 isoform 2 [Homo sapiens]
Length = 251
Score = 47.8 bits (112), Expect = 2e-05
Identities = 32/122 (26%), Positives = 61/122 (50%), Gaps = 9/122 (7%)
Query: 225 AESRALAKERQKKDNHNLIERRRRFNINDRIKELGMLIPKANDLDVR--WNKGTILKASV 282
+E+ ++ +++ HN +ERRRR IN+ I +L +IP + + +KG IL +
Sbjct: 130 SEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQSKGGILSKAC 189
Query: 283 DYIRRMQKDLQKSRELENHSRRLEMTNKQLWLRIQELE-------MQARVHGLPTTSPSG 335
DYI+ +++ + E +L++ N L ++++L+ Q R HGL +
Sbjct: 190 DYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHHGLEVVIKND 249
Query: 336 MN 337
N
Sbjct: 250 SN 251
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 47.4 bits (111), Expect = 3e-05
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 12/140 (8%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPP-----TPAINTPVHFQSP 62
R+ +M +Q QQ++Q+++ QQQ QQQQQQQQ Q PP +P+++ + +
Sbjct: 1242 RVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTM 1301
Query: 63 PPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAAS 122
P P + Q +Y + Q Q +S ++ + P+Q P A+
Sbjct: 1302 PQAPPQQFPYQ------PNYGMGQ-QPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAA 1354
Query: 123 PGVRAGHVLSSSAGNSAPNS 142
++ + +GN A NS
Sbjct: 1355 SIYQSSEMKGWPSGNLARNS 1374
Score = 32.7 bits (73), Expect = 0.74
Identities = 19/44 (43%), Positives = 24/44 (54%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
++S+ G M Q +E +QQ V MQQQQQQQQQQ
Sbjct: 1214 VSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQ 1257
Score = 31.6 bits (70), Expect = 1.6
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L Q++ +++++ QQ+ M QQQQQQQQQQ
Sbjct: 1221 LNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQ 1258
>gi|32307124 nuclear receptor coactivator 3 isoform b [Homo sapiens]
Length = 1420
Score = 47.4 bits (111), Expect = 3e-05
Identities = 37/140 (26%), Positives = 64/140 (45%), Gaps = 12/140 (8%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPP-----TPAINTPVHFQSP 62
R+ +M +Q QQ++Q+++ QQQ QQQQQQQQ Q PP +P+++ + +
Sbjct: 1238 RVAMMMQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTQAFSPPPNVTASPSMDGLLAGPTM 1297
Query: 63 PPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHISPAQGSPKPPPAAS 122
P P + Q +Y + Q Q +S ++ + P+Q P A+
Sbjct: 1298 PQAPPQQFPYQ------PNYGMGQ-QPDPAFGRVSSPPNAMMSSRMGPSQNPMMQHPQAA 1350
Query: 123 PGVRAGHVLSSSAGNSAPNS 142
++ + +GN A NS
Sbjct: 1351 SIYQSSEMKGWPSGNLARNS 1370
Score = 31.6 bits (70), Expect = 1.6
Identities = 15/38 (39%), Positives = 23/38 (60%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L Q++ +++++ QQ+ M QQQQQQQQQQ
Sbjct: 1217 LNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQ 1254
>gi|189491748 ataxin 1 [Homo sapiens]
Length = 815
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQL------------GGP 48
+ + +G Q +A+Q++Q+++ QQQ H QQQQQQQQQQ G P
Sbjct: 180 LLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSP 239
Query: 49 PTPAINTPVHFQSPPPVPG 67
P N VH S P G
Sbjct: 240 PPAQQNQYVHISSSPQNTG 258
>gi|51479158 ataxin 1 [Homo sapiens]
Length = 815
Score = 47.4 bits (111), Expect = 3e-05
Identities = 28/79 (35%), Positives = 38/79 (48%), Gaps = 12/79 (15%)
Query: 1 MASRIGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQL------------GGP 48
+ + +G Q +A+Q++Q+++ QQQ H QQQQQQQQQQ G P
Sbjct: 180 LLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSP 239
Query: 49 PTPAINTPVHFQSPPPVPG 67
P N VH S P G
Sbjct: 240 PPAQQNQYVHISSSPQNTG 258
>gi|226246533 TOX high mobility group box family member 3 isoform 2
[Homo sapiens]
Length = 571
Score = 46.6 bits (109), Expect = 5e-05
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 28/123 (22%)
Query: 8 RMQLMREQAQQEEQRERMQQQAV-MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVP 66
+MQL ++Q QQ++Q ++MQQQ + H M QQ QQQ QQ HFQ
Sbjct: 437 QMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ------------QHFQH----- 479
Query: 67 GEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHI------SPAQGSPKPPPA 120
+Q +L+ + QQ Q++++ L + + H+ SP Q SP
Sbjct: 480 ----HMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQI 535
Query: 121 ASP 123
SP
Sbjct: 536 TSP 538
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 28/118 (23%)
Query: 8 RMQLMREQAQQEEQ-----RERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSP 62
+MQ M++Q Q+ Q +++MQQQ H+MQQ QQQQQ H Q
Sbjct: 450 QMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQ--------------HLQQ- 494
Query: 63 PPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHIS---PAQGSPKP 117
++ + Q + LQQ QH + + S + A+ I+ PA GSP+P
Sbjct: 495 -----QINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQP 547
>gi|226054295 TOX high mobility group box family member 3 isoform 1
[Homo sapiens]
Length = 576
Score = 46.6 bits (109), Expect = 5e-05
Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 28/123 (22%)
Query: 8 RMQLMREQAQQEEQRERMQQQAV-MHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVP 66
+MQL ++Q QQ++Q ++MQQQ + H M QQ QQQ QQ HFQ
Sbjct: 442 QMQLQQQQQQQQQQMQQMQQQQLQQHQMHQQIQQQMQQ------------QHFQH----- 484
Query: 67 GEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHI------SPAQGSPKPPPA 120
+Q +L+ + QQ Q++++ L + + H+ SP Q SP
Sbjct: 485 ----HMQQHLQQQQQHLQQQINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQI 540
Query: 121 ASP 123
SP
Sbjct: 541 TSP 543
Score = 42.4 bits (98), Expect = 0.001
Identities = 36/118 (30%), Positives = 54/118 (45%), Gaps = 28/118 (23%)
Query: 8 RMQLMREQAQQEEQ-----RERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSP 62
+MQ M++Q Q+ Q +++MQQQ H+MQQ QQQQQ H Q
Sbjct: 455 QMQQMQQQQLQQHQMHQQIQQQMQQQHFQHHMQQHLQQQQQ--------------HLQQ- 499
Query: 63 PPVPGEVLKVQSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHIS---PAQGSPKP 117
++ + Q + LQQ QH + + S + A+ I+ PA GSP+P
Sbjct: 500 -----QINQQQLQQQLQQRLQLQQLQHMQHQSQPSPRQHSPVASQITSPIPAIGSPQP 552
>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
Length = 715
Score = 46.2 bits (108), Expect = 6e-05
Identities = 20/38 (52%), Positives = 29/38 (76%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L +QL+++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 146 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 183
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPG 67
+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ P A Q +
Sbjct: 153 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 212
Query: 68 EVLKVQSYLENPTSYHLQQSQH 89
+ L Q L LQQ QH
Sbjct: 213 QQLVFQQQLLQ--MQQLQQQQH 232
Score = 42.7 bits (99), Expect = 7e-04
Identities = 19/38 (50%), Positives = 27/38 (71%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 151 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 188
Score = 41.6 bits (96), Expect = 0.002
Identities = 19/38 (50%), Positives = 26/38 (68%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 150 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 187
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/34 (47%), Positives = 24/34 (70%)
Query: 11 LMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+M +Q Q +E ++ Q+Q + +QQQQQQQQQQ
Sbjct: 128 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 161
Score = 33.1 bits (74), Expect = 0.57
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 2/38 (5%)
Query: 9 MQLMREQAQQ--EEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ L ++Q Q+ ++Q+E++ Q + QQQQQQQQQQ
Sbjct: 128 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 165
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
++Q ++ Q++ + +QQQ QQQQQQQQQQ
Sbjct: 134 QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 170
Score = 30.0 bits (66), Expect = 4.8
Identities = 14/38 (36%), Positives = 24/38 (63%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++E ++++++ +Q QQQQQQQQQQ
Sbjct: 130 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 167
Score = 30.0 bits (66), Expect = 4.8
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ QL +Q+EQ Q QQQQQQQQQQ
Sbjct: 132 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 168
Score = 29.6 bits (65), Expect = 6.3
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 10 QLMREQAQQEEQRERMQQQAVMHY--MQQQQQQQQQQL 45
Q +Q QQ++Q++ QQ V +Q QQ QQQQ L
Sbjct: 196 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 233
Score = 29.3 bits (64), Expect = 8.2
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q + Q QQ ++ + QQ+ + + QQQQQQQQQ
Sbjct: 124 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ 160
>gi|22538413 forkhead box P2 isoform III [Homo sapiens]
Length = 623
Score = 46.2 bits (108), Expect = 6e-05
Identities = 20/38 (52%), Positives = 29/38 (76%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L +QL+++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 54 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 91
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPG 67
+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ P A Q +
Sbjct: 61 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 120
Query: 68 EVLKVQSYLENPTSYHLQQSQH 89
+ L Q L LQQ QH
Sbjct: 121 QQLVFQQQLLQ--MQQLQQQQH 140
Score = 42.7 bits (99), Expect = 7e-04
Identities = 19/38 (50%), Positives = 27/38 (71%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 59 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 96
Score = 41.6 bits (96), Expect = 0.002
Identities = 19/38 (50%), Positives = 26/38 (68%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 58 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 95
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/34 (47%), Positives = 24/34 (70%)
Query: 11 LMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+M +Q Q +E ++ Q+Q + +QQQQQQQQQQ
Sbjct: 36 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 69
Score = 33.1 bits (74), Expect = 0.57
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 2/38 (5%)
Query: 9 MQLMREQAQQ--EEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ L ++Q Q+ ++Q+E++ Q + QQQQQQQQQQ
Sbjct: 36 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 73
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
++Q ++ Q++ + +QQQ QQQQQQQQQQ
Sbjct: 42 QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 78
Score = 30.0 bits (66), Expect = 4.8
Identities = 14/38 (36%), Positives = 24/38 (63%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++E ++++++ +Q QQQQQQQQQQ
Sbjct: 38 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 75
Score = 30.0 bits (66), Expect = 4.8
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ QL +Q+EQ Q QQQQQQQQQQ
Sbjct: 40 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 76
Score = 29.6 bits (65), Expect = 6.3
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 10 QLMREQAQQEEQRERMQQQAVMHY--MQQQQQQQQQQL 45
Q +Q QQ++Q++ QQ V +Q QQ QQQQ L
Sbjct: 104 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 141
Score = 29.3 bits (64), Expect = 8.2
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q + Q QQ ++ + QQ+ + + QQQQQQQQQ
Sbjct: 32 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ 68
>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
Length = 740
Score = 46.2 bits (108), Expect = 6e-05
Identities = 20/38 (52%), Positives = 29/38 (76%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L +QL+++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 171 LHLQLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 208
Score = 45.4 bits (106), Expect = 1e-04
Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 2/82 (2%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPTPAINTPVHFQSPPPVPG 67
+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ P A Q +
Sbjct: 178 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAA 237
Query: 68 EVLKVQSYLENPTSYHLQQSQH 89
+ L Q L LQQ QH
Sbjct: 238 QQLVFQQQLLQ--MQQLQQQQH 257
Score = 42.7 bits (99), Expect = 7e-04
Identities = 19/38 (50%), Positives = 27/38 (71%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 176 LQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 213
Score = 41.6 bits (96), Expect = 0.002
Identities = 19/38 (50%), Positives = 26/38 (68%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L Q ++Q QQ++Q+++ QQQ QQQQQQQQQQ
Sbjct: 175 LLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 212
Score = 35.0 bits (79), Expect = 0.15
Identities = 16/34 (47%), Positives = 24/34 (70%)
Query: 11 LMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+M +Q Q +E ++ Q+Q + +QQQQQQQQQQ
Sbjct: 153 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQ 186
Score = 33.1 bits (74), Expect = 0.57
Identities = 16/38 (42%), Positives = 26/38 (68%), Gaps = 2/38 (5%)
Query: 9 MQLMREQAQQ--EEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ L ++Q Q+ ++Q+E++ Q + QQQQQQQQQQ
Sbjct: 153 VMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 190
Score = 32.0 bits (71), Expect = 1.3
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
++Q ++ Q++ + +QQQ QQQQQQQQQQ
Sbjct: 159 QLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQQQ 195
Score = 30.0 bits (66), Expect = 4.8
Identities = 14/38 (36%), Positives = 24/38 (63%)
Query: 7 LRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
L+ Q ++E ++++++ +Q QQQQQQQQQQ
Sbjct: 155 LQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQ 192
Score = 30.0 bits (66), Expect = 4.8
Identities = 16/37 (43%), Positives = 19/37 (51%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ QL +Q+EQ Q QQQQQQQQQQ
Sbjct: 157 QQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQQQQ 193
Score = 29.6 bits (65), Expect = 6.3
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 2/38 (5%)
Query: 10 QLMREQAQQEEQRERMQQQAVMHY--MQQQQQQQQQQL 45
Q +Q QQ++Q++ QQ V +Q QQ QQQQ L
Sbjct: 221 QAKEQQQQQQQQQQLAAQQLVFQQQLLQMQQLQQQQHL 258
Score = 29.3 bits (64), Expect = 8.2
Identities = 15/37 (40%), Positives = 23/37 (62%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQ 44
+ Q + Q QQ ++ + QQ+ + + QQQQQQQQQ
Sbjct: 149 QQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQ 185
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 45.4 bits (106), Expect = 1e-04
Identities = 31/88 (35%), Positives = 42/88 (47%), Gaps = 2/88 (2%)
Query: 5 IGLRMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGG-PPTPAINTPVHFQSPP 63
I L Q ++ QQ++Q +R+ Q + QQQQQQQQQQ P I P Q P
Sbjct: 221 IKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQP-PMQQPQ 279
Query: 64 PVPGEVLKVQSYLENPTSYHLQQSQHQK 91
P P + L Q + T +H Q Q+
Sbjct: 280 PPPSQALPQQLQQMHHTQHHQPPPQPQQ 307
Score = 42.4 bits (98), Expect = 0.001
Identities = 33/132 (25%), Positives = 54/132 (40%), Gaps = 19/132 (14%)
Query: 8 RMQLMREQAQQEEQRERMQQQAVMHYMQQQQQQQQQQLGGPPT-------PAINTPVHFQ 60
++QL + QQ++Q+++ QQQ QQQQQQQQQQ + + Q
Sbjct: 152 QLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQ 211
Query: 61 SPPPVPGEVLKV-----------QSYLENPTSYHLQQSQHQKVREYLSETYGNKFAAHI- 108
++K+ Q L+ LQQ Q Q+ ++ + + I
Sbjct: 212 QQQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQ 271
Query: 109 SPAQGSPKPPPA 120
P P+PPP+
Sbjct: 272 QPPMQQPQPPPS 283
Score = 30.4 bits (67), Expect = 3.7
Identities = 41/162 (25%), Positives = 57/162 (35%), Gaps = 29/162 (17%)
Query: 321 MQARVHGLPTTSPSGMNMAELA------QQVVKQELPSEEGPGEALMLGAEVPDPEPLPA 374
M R PTT+ S + + + QV + LP P G +V P+ +P
Sbjct: 395 MHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSPSP----GQQVQTPQSMP- 449
Query: 375 LPPQAPLPLPTQPPSPFHHLDFSHSLSFGGREDEGPPGYPEPLAPGHGSPFPSLSKKDLD 434
PP P P P QP S GP P P SP P S+ +
Sbjct: 450 -PPPQPSPQPGQPSS-----------QPNSNVSSGPAPSPSSFLP---SPSPQPSQSPVT 494
Query: 435 LMLLDDSLLPLASDPLLSTMSPEASKASSRRSSFSMEEGDVL 476
+ +P + PL + ++P S S S EE L
Sbjct: 495 ARTPQNFSVP-SPGPLNTPVNP--SSVMSPAGSSQAEEQQYL 533
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,466,244
Number of Sequences: 37866
Number of extensions: 1412339
Number of successful extensions: 18694
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 260
Number of HSP's successfully gapped in prelim test: 603
Number of HSP's that attempted gapping in prelim test: 10910
Number of HSP's gapped (non-prelim): 5203
length of query: 476
length of database: 18,247,518
effective HSP length: 106
effective length of query: 370
effective length of database: 14,233,722
effective search space: 5266477140
effective search space used: 5266477140
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.