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Search of human proteins with 119703755
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|119703755 laminin, beta 2 precursor [Homo sapiens]
(1798 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|119703755 laminin, beta 2 precursor [Homo sapiens] 3804 0.0
gi|167614504 laminin, beta 1 precursor [Homo sapiens] 1946 0.0
gi|143770880 laminin, beta 4 [Homo sapiens] 1375 0.0
gi|62868217 laminin, beta 3 precursor [Homo sapiens] 468 e-131
gi|62868215 laminin, beta 3 precursor [Homo sapiens] 468 e-131
gi|189083719 laminin, beta 3 precursor [Homo sapiens] 468 e-131
gi|93204871 netrin 4 [Homo sapiens] 358 3e-98
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 306 1e-82
gi|21264602 laminin alpha 5 [Homo sapiens] 305 2e-82
gi|110611156 laminin, gamma 3 precursor [Homo sapiens] 305 3e-82
gi|38788416 laminin, alpha 1 precursor [Homo sapiens] 289 1e-77
gi|219842266 usherin isoform B [Homo sapiens] 271 3e-72
gi|219842259 usherin isoform A [Homo sapiens] 271 3e-72
gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo s... 266 2e-70
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa... 266 2e-70
gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens] 257 8e-68
gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens] 257 8e-68
gi|148613884 netrin 1 [Homo sapiens] 247 8e-65
gi|5453810 netrin 3 [Homo sapiens] 227 7e-59
gi|122937440 multiple EGF-like-domains 9 [Homo sapiens] 192 3e-48
gi|181336739 multiple EGF-like-domains 11 [Homo sapiens] 177 1e-43
gi|14192943 multiple EGF-like-domains 10 [Homo sapiens] 175 3e-43
gi|24308065 netrin 5 [Homo sapiens] 175 3e-43
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens] 175 4e-43
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s... 162 4e-39
gi|164414431 netrin G1 isoform 1 [Homo sapiens] 160 8e-39
gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens] 159 2e-38
gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens] 159 2e-38
gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens] 159 2e-38
gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens] 159 3e-38
>gi|119703755 laminin, beta 2 precursor [Homo sapiens]
Length = 1798
Score = 3804 bits (9864), Expect = 0.0
Identities = 1798/1798 (100%), Positives = 1798/1798 (100%)
Query: 1 MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRAD 60
MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRAD
Sbjct: 1 MELTSRERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRAD 60
Query: 61 RLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRR 120
RLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRR
Sbjct: 61 RLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRR 120
Query: 121 AAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY 180
AAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY
Sbjct: 121 AAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSY 180
Query: 181 DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL 240
DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL
Sbjct: 181 DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL 240
Query: 241 KITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPA 300
KITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPA
Sbjct: 241 KITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPA 300
Query: 301 HAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDM 360
HAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDM
Sbjct: 301 HAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDM 360
Query: 361 AVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG 420
AVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG
Sbjct: 361 AVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG 420
Query: 421 GRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPG 480
GRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPG
Sbjct: 421 GRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPG 480
Query: 481 STPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ 540
STPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ
Sbjct: 481 STPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQ 540
Query: 541 CHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFV 600
CHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFV
Sbjct: 541 CHCRQHMVGRRCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFV 600
Query: 601 RLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPK 660
RLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPK
Sbjct: 601 RLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPK 660
Query: 661 DDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVL 720
DDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVL
Sbjct: 661 DDRIQGTLQPHARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGPGLLIDSLVL 720
Query: 721 LPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGA 780
LPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGA
Sbjct: 721 LPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGA 780
Query: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840
LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS
Sbjct: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840
Query: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHT 900
SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHT
Sbjct: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHT 900
Query: 901 GGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGY 960
GGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGY
Sbjct: 901 GGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGY 960
Query: 961 TGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCA 1020
TGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCA
Sbjct: 961 TGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCA 1020
Query: 1021 HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA 1080
HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA
Sbjct: 1021 HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA 1080
Query: 1081 PNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC 1140
PNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC
Sbjct: 1081 PNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC 1140
Query: 1141 HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV 1200
HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV
Sbjct: 1141 HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV 1200
Query: 1201 VQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVE 1260
VQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVE
Sbjct: 1201 VQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVE 1260
Query: 1261 ATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDL 1320
ATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDL
Sbjct: 1261 ATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDL 1320
Query: 1321 LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFN 1380
LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFN
Sbjct: 1321 LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFN 1380
Query: 1381 SKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGL 1440
SKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGL
Sbjct: 1381 SKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGL 1440
Query: 1441 SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANA 1500
SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANA
Sbjct: 1441 SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANA 1500
Query: 1501 SRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIA 1560
SRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIA
Sbjct: 1501 SRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIA 1560
Query: 1561 ERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGI 1620
ERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGI
Sbjct: 1561 ERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGI 1620
Query: 1621 AQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLA 1680
AQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLA
Sbjct: 1621 AQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLA 1680
Query: 1681 ASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARD 1740
ASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARD
Sbjct: 1681 ASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARD 1740
Query: 1741 LLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ 1798
LLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ
Sbjct: 1741 LLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTCQ 1798
>gi|167614504 laminin, beta 1 precursor [Homo sapiens]
Length = 1786
Score = 1946 bits (5041), Expect = 0.0
Identities = 899/1785 (50%), Positives = 1214/1785 (68%), Gaps = 15/1785 (0%)
Query: 22 LLLSVLAATLAQAPAPDVP---GCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCI 78
L S LA A+ A + GC+ GSCYPATGDLL+GRA +L+ +STCGL+ P+PYCI
Sbjct: 7 LAFSFLALCRARVRAQEPEFSYGCAEGSCYPATGDLLIGRAQKLSVTSTCGLHKPEPYCI 66
Query: 79 VSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLD 138
VSHLQ++KKCF+C+S+ P+ NP SH I+NVVT+FAP R WWQSENG+ VTIQLD
Sbjct: 67 VSHLQEDKKCFICNSQDPYHETLNPDSHLIENVVTTFAPNRLKIWWQSENGVENVTIQLD 126
Query: 139 LEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWD 198
LEAEFHFTHLIMTFKTFRPAAML+ERS+DFG+TW VYRYF+YDC A FPG+ P + D
Sbjct: 127 LEAEFHFTHLIMTFKTFRPAAMLIERSSDFGKTWGVYRYFAYDCEASFPGISTGPMKKVD 186
Query: 199 DVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDN 258
D++C+SRYS+IEPSTEGEVI+R LDPA I DPYS RIQNLLKITNLR+ +LHTLGDN
Sbjct: 187 DIICDSRYSDIEPSTEGEVIFRALDPAFKIEDPYSPRIQNLLKITNLRIKFVKLHTLGDN 246
Query: 259 LLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRG 318
LLD R EIREKYYYA+Y++VVRGNCFCYGHASECAP G EGMVHG C+C+HNT+G
Sbjct: 247 LLDSRMEIREKYYYAVYDMVVRGNCFCYGHASECAPVDGFNEEVEGMVHGHCMCRHNTKG 306
Query: 319 LNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQ 378
LNCE C DFY DLPWRPAE +S+AC+KC C+ H+ SCHFDMAVYLA+GNVSGGVCD CQ
Sbjct: 307 LNCELCMDFYHDLPWRPAEGRNSNACKKCNCNEHSISCHFDMAVYLATGNVSGGVCDDCQ 366
Query: 379 HNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQC 438
HNT GR+CE C+PF+Y+ P +D+RDP C C CDP GSQ+ G CDS+ D + GL++GQC
Sbjct: 367 HNTMGRNCEQCKPFYYQHPERDIRDPNFCERCTCDPAGSQNEGICDSYTDFSTGLIAGQC 426
Query: 439 RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
RCK +V G C C++GF+ LS D GC+ C CN GT+PG PCD +G CYCKRLVT
Sbjct: 427 RCKLNVEGEHCDVCKEGFYDLSSEDPFGCKSCACNPLGTIPGGNPCDSETGHCYCKRLVT 486
Query: 499 GRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPG 558
G+ CD+CLP HWGLS+DL GCRPCDCD+GGAL+ C +GQC CR HM+GR+C +V+PG
Sbjct: 487 GQHCDQCLPEHWGLSNDLDGCRPCDCDLGGALNNSCFAESGQCSCRPHMIGRQCNEVEPG 546
Query: 559 YFRPFLDHLIWEAEDTR-GQVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPK 617
Y+ LDH ++EAE+ G + +VER PSWTG+GFVR+ EG LEF + ++P
Sbjct: 547 YYFATLDHYLYEAEEANLGPGVSIVERQYIQDRIPSWTGAGFVRVPEGAYLEFFIDNIPY 606
Query: 618 AMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGHLVPKDDRIQGTLQPHARYLIF 677
+M+YD+L+R EPQ+P+ W + + VQRPG +P S CG+ +P DD +L P +RY++
Sbjct: 607 SMEYDILIRYEPQLPDHWEKAVITVQRPGRIPTSSRCGNTIPDDDNQVVSLSPGSRYVVL 666
Query: 678 PNPVCLEPGISYKLHLKLVR-TGGSAQPETPYSGPGLLIDSLVLLPRVLVLEMF----SG 732
P PVC E G +Y + L+L + T + E+PY+ LIDSLVL+P L++F SG
Sbjct: 667 PRPVCFEKGTNYTVRLELPQYTSSDSDVESPYT----LIDSLVLMPYCKSLDIFTVGGSG 722
Query: 733 GDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLS 792
TF+RY+C E KT ++ C ++ S+S L++ L C+C+PQGSLS
Sbjct: 723 DGVVTNSAWETFQRYRCLENSRSVVKTPMTDVCRNIIFSISALLHQTGLACECDPQGSLS 782
Query: 793 SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLC 852
S C+P+GGQC C+P VVGR C+ CAPG +GFGP+GC+ C+C +G++++ C +GQC C
Sbjct: 783 SVCDPNGGQCQCRPNVVGRTCNRCAPGTFGFGPSGCKPCECHLQGSVNAFCNPVTGQCHC 842
Query: 853 RTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGF 912
G + +CDRC G WGFPSC+PC CNGHAD+C+ TG CL C+D+T G +CERC+AG+
Sbjct: 843 FQGVYARQCDRCLPGHWGFPSCQPCQCNGHADDCDPVTGECLNCQDYTMGHNCERCLAGY 902
Query: 913 HGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
+GDP + G CRPCPCP+GP S R FA SC+QD + Q+ C C GY G RC+ CA G+
Sbjct: 903 YGDPIIGSGDHCRPCPCPDGPDSGRQFARSCYQDPVTLQLACVCDPGYIGSRCDDCASGY 962
Query: 973 FGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR 1032
FG+PS GG CQ C+C NID DP+ACD TG+CL+CL+HTEG HC C+ G++G A +
Sbjct: 963 FGNPSEVGGSCQPCQCHNNIDTTDPEACDKETGRCLKCLYHTEGEHCQFCRFGYYGDALQ 1022
Query: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092
Q C +C CN LGT + C D C CD ++GQC CLPNV G +CDRCAPN W L SG GC
Sbjct: 1023 QDCRKCVCNYLGTVQEHCNGSD-CQCDKATGQCLCLPNVIGQNCDRCAPNTWQLASGTGC 1081
Query: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDT 1152
PC C+ + + GP+CNEFTGQC C GFGGRTCSECQEL WGDP ++C ACDCD RGI+T
Sbjct: 1082 DPCNCNAAHSFGPSCNEFTGQCQCMPGFGGRTCSECQELFWGDPDVECRACDCDPRGIET 1141
Query: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLE 1212
PQC + TG C C GV G RCD+C RG+SG+FP C PCH CF WD ++ +L RT R
Sbjct: 1142 PQCDQSTGQCVCVEGVEGPRCDKCTRGYSGVFPDCTPCHQCFALWDVIIAELTNRTHRFL 1201
Query: 1213 QRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEA 1272
++A+ L+ +GV+G + + ++ K+ ++ I+ A++ +A + EE + I +
Sbjct: 1202 EKAKALKISGVIGPYRETVDSVERKVSEIKDIL-AQSPAAEPLKNIGNLFEEAEKLIKDV 1260
Query: 1273 TEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDS 1332
TE + Q+E L+D ++ + L L+ + +L+ T+++L + L+ +K+S+ GA DS
Sbjct: 1261 TEMMAQVEVKLSDTTSQSNSTAKELDSLQTEAESLDNTVKELAEQLEFIKNSDIRGALDS 1320
Query: 1333 IRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGK 1392
I S EAE R N S S V SA R R E +M ++ F K R L +
Sbjct: 1321 ITKYFQMSLEAEERVNASTTEPNSTVEQSALMRDRVEDVMMERESQFKEKQEEQARLLDE 1380
Query: 1393 LSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLA 1452
L+ +L L+ E+ CG P A C+ + CGG CR ++G+ +CGG C G A A
Sbjct: 1381 LAGKLQSLDLSAAAEMTCGTPPGASCSETECGGPNCRTDEGERKCGGPGCGGLVTVAHNA 1440
Query: 1453 LGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQEL 1512
+A ++ ALAE + V+E + +A EA+Q A+ L K NA++ +++++N+EL
Sbjct: 1441 WQKAMDLDQDVLSALAEVEQLSKMVSEAKLRADEAKQSAEDILLKTNATKEKMDKSNEEL 1500
Query: 1513 QELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAI 1572
+ LI+ +++FL Q+ AD DSIE VA VL++ +P++ +Q+Q+L I ERV SL+ V+ I
Sbjct: 1501 RNLIKQIRNFLTQDSADLDSIEAVANEVLKMEMPSTPQQLQNLTEDIRERVESLSQVEVI 1560
Query: 1573 LARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADT 1632
L + D+ RAE LL++A+RA A D K A+ V+ ALEEA++AQ A+ AI+ A D
Sbjct: 1561 LQHSAADIARAEMLLEEAKRASKSATDVKVTADMVKEALEEAEKAQVAAEKAIKQADEDI 1620
Query: 1633 RDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQ 1692
+ T+ L ++ A +E L +A +R +L+ +E LK K A NS A E+ + +
Sbjct: 1621 QGTQNLLTSIESETAASEETLFNASQRISELERNVEELKRKAAQNSGEAEYIEKVVYTVK 1680
Query: 1693 GRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRL 1752
A++ ++ L G L ++Y+ V+ L +K + A+ +AE L++EA+ LL A KLQ L
Sbjct: 1681 QSAEDVKKTLDGELDEKYKKVENLIAKKTEESADARRKAEMLQNEAKTLLAQANSKLQLL 1740
Query: 1753 QELEGTYEENERALESKAAQLDGLEARMRSVLQAINLQVQIYNTC 1797
++LE YE+N+R LE KA +L LE +RS+L+ I+ +V +Y+TC
Sbjct: 1741 KDLERKYEDNQRYLEDKAQELARLEGEVRSLLKDISQKVAVYSTC 1785
>gi|143770880 laminin, beta 4 [Homo sapiens]
Length = 1761
Score = 1375 bits (3560), Expect = 0.0
Identities = 718/1817 (39%), Positives = 1035/1817 (56%), Gaps = 91/1817 (5%)
Query: 14 LPWELRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGP 73
+ ++L L L L L+ + AQ C+RG+C+P TGDLLVGR +L ASSTCGL+
Sbjct: 1 MQFQLTLFLHLGWLSYSKAQ------DDCNRGACHPTTGDLLVGRNTQLMASSTCGLSRA 54
Query: 74 QPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAV 133
Q YCI+S+L+ E+KCF+CDSR P+ D P+SH I+NV+ SF P R WWQSENG+ V
Sbjct: 55 QKYCILSYLEGEQKCFICDSRFPYDPYDQPNSHTIENVIVSFEPDREKKWWQSENGLDHV 114
Query: 134 TIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAP 193
+I+LDLEA F F+HLI+TFKTFRPAAMLVERS D+G W V++YF+ DC FP +
Sbjct: 115 SIRLDLEALFRFSHLILTFKTFRPAAMLVERSTDYGHNWKVFKYFAKDCATSFPNITSGQ 174
Query: 194 PRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLH 253
+ D+VC+S+YS+IEPST GEV+ +VLDP+ I +PYS IQ+L+ +TNLR+N T+LH
Sbjct: 175 AQGVGDIVCDSKYSDIEPSTGGEVVLKVLDPSFEIENPYSPYIQDLVTLTNLRINFTKLH 234
Query: 254 TLGDNLLDPRR-EIREKYYYALYELVVRGNCFCYGHASECAPAP---GAPAHAEGMVHGA 309
TLGD LL R+ + +KYYYALYE++VRG+CFC GHASEC P G GMVHG
Sbjct: 235 TLGDALLGRRQNDSLDKYYYALYEMIVRGSCFCNGHASECRPMQKMRGDVFSPPGMVHGQ 294
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
C+C+HNT G NCE+C+DF++D PWRPA D +ACR C C+ H+ CHFDM YLASG +
Sbjct: 295 CVCQHNTDGPNCERCKDFFQDAPWRPAADLQDNACRSCSCNSHSSRCHFDMTTYLASGGL 354
Query: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
SGGVC+ CQHNT G+HC+ CRP FYRDP K + DP C C+CDP G+ GG C SH DP
Sbjct: 355 SGGVCEDCQHNTEGQHCDRCRPLFYRDPLKTISDPYACIPCECDPDGTISGGICVSHSDP 414
Query: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
ALG V+GQC CKE+V G +C QC+ +GLS +D LGC+ C CN G++P T CD ++G
Sbjct: 415 ALGSVAGQCLCKENVEGAKCDQCKPNHYGLSATDPLGCQPCDCNPLGSLPFLT-CDVDTG 473
Query: 490 SCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVG 549
C C VTG C+ C G+WGL + L GC PCDCD+GGA C GQC CR H+ G
Sbjct: 474 QCLCLSYVTGAHCEECTVGYWGLGNHLHGCSPCDCDIGGAYSNVCSPKNGQCECRPHVTG 533
Query: 550 RRCEQVQPGYFRPFLDHLIWEAE-------------DTRGQ--VLDVVERLVTPGETPSW 594
R C + PGYF L+ ++EAE +T GQ + VV PG +W
Sbjct: 534 RSCSEPAPGYFFAPLNFYLYEAEEATTLQGLAPLGSETFGQSPAVHVVLGEPVPGNPVTW 593
Query: 595 TGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLC 654
TG GF R+ G L F V ++P +D+ + + E Q W ++++V PG
Sbjct: 594 TGPGFARVLPGAGLRFAVNNIPFPVDFTIAIHYETQSAADWT-VQIVVNPPGG------S 646
Query: 655 GHLVPK--DDRIQGTLQPHA-RYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYSGP 711
H +PK + Q P A R ++ P P+CLEP + Y + V Q E+ ++
Sbjct: 647 EHCIPKTLQSKPQSFALPAATRIMLLPTPICLEPDVQYSID---VYFSQPLQGES-HAHS 702
Query: 712 GLLIDSLVLLPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPS---EACAPL 768
+L+DSL L+P++ LE F + + YQ H + S P AC L
Sbjct: 703 HVLVDSLGLIPQINSLENFCS--------KQDLDEYQLHNCVEIASAMGPQVLPGACERL 754
Query: 769 LISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC 828
+IS+S +++GA+ C+C+PQGS+ S C+ GGQC CKP VVGR CD C+ G Y G GC
Sbjct: 755 IISMSAKLHDGAVACKCHPQGSVGSSCSRLGGQCQCKPLVVGRCCDRCSTGSYDLGHHGC 814
Query: 829 QACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNT 888
C C +G+ ++C++ +GQC C G RCDRC G +GFPSC PC CN A+ C+
Sbjct: 815 HPCHCHPQGSKDTVCDQVTGQCPCHGEVSGRRCDRCLAGYFGFPSCHPCPCNRFAELCDP 874
Query: 889 HTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEY 948
TG+C C T G +CERCI G++G+P G CRPC CP+ P S ++FA SC+Q+ +
Sbjct: 875 ETGSCFNCGGFTTGRNCERCIDGYYGNP--SSGQPCRPCLCPDDPSSNQYFAHSCYQNLW 932
Query: 949 SQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCL 1008
S ++C+C GYTG +C C+ G +G+P G CQ C C+ NID DP++C TG+CL
Sbjct: 933 SSDVICNCLQGYTGTQCGECSTGFYGNPRISGAPCQPCACNNNIDVTDPESCSRVTGECL 992
Query: 1009 RCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQC-PSPDQCHCDPSSGQCPC 1067
RCLH+T+G +C CKPG +G A Q+C RC+C+ G +P +C P C CDP +G CPC
Sbjct: 993 RCLHNTQGANCQLCKPGHYGSALNQTCRRCSCHASGVSPMECPPGGGACLCDPVTGACPC 1052
Query: 1068 LPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE 1127
LPNV G +CDRCA +WNL G GCQ C C P ++ C++ TGQC C+ G+GG+ CSE
Sbjct: 1053 LPNVTGLACDRCADGYWNLVPGRGCQSCDCDPRTSQSSHCDQLTGQCPCKLGYGGKRCSE 1112
Query: 1128 CQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPAC 1187
CQE ++GDP +C CDC+ G P C TG C CR GVSG RCD+CARG S FP C
Sbjct: 1113 CQENYYGDPPGRCIPCDCNRAGTQKPICDPDTGMCRCREGVSGQRCDRCARGHSQEFPTC 1172
Query: 1188 HPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-QTGVLGAFESSFWHMQEKLGIVQGIVG 1246
CH CF WD + L+ Q L + A ++ + L E+ F ++ + ++ I+
Sbjct: 1173 LQCHLCFDQWDHTISSLSKAVQGLMRLAANMEDKRETLPVCEADFKDLRGNVSEIERILK 1232
Query: 1247 ARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLA 1306
+ ++ + + +RR+I + E L + + D++D +ER +
Sbjct: 1233 HPVFPSGKFLKVKDYHDSVRRQIMQLNEQLKAV-YEFQDLKDT----------IERAKNE 1281
Query: 1307 LNLTLRQLDQHLDL---LKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSAS 1363
+L L L + +DL + +++ + ++I+ + S+ AE++ N ++ S ++ SA+
Sbjct: 1282 ADLLLEDLQEEIDLQSSVLNASIADSSENIKKYYHISSSAEKKINETS----STINTSAN 1337
Query: 1364 ARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPC 1423
R+ ++D SK + L ++ + +NE VCG PG+ PC PC
Sbjct: 1338 TRNDLLTILDT----LTSKGNLSLERLKQIKIP----DIQILNEKVCGDPGNVPCVPLPC 1389
Query: 1424 GGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQ 1483
GGA C G +C G C+G+ + AL +A+ ++ ++ + + +++ Q
Sbjct: 1390 GGALCTGRKGHRKCRGPGCHGSLTLSTNALQKAQEAKSIIRNLDKQVRGLKNQIESISEQ 1449
Query: 1484 ASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLEL 1543
A ++ A +K R Q + + + I+ VK+FL +E P+ IE VA VL++
Sbjct: 1450 AEVSKNNALQLREKLGNIRNQSDSEEENINLFIKKVKNFLLEENVPPEDIEKVANGVLDI 1509
Query: 1544 SIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQK 1603
+P ++ + I + ++ D R + A++LL A+ A A
Sbjct: 1510 HLPIPSQNLTDELVKIQKHMQLCEDYRTDENRLNEEADGAQKLLVKAKAAEKAANILLNL 1569
Query: 1604 AETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQL 1663
+T+ L++AQ QG A I A+ ++ + Q + + + L A +R+
Sbjct: 1570 DKTLN-QLQQAQITQGRANSTITQLTANITKIKKNVLQAENQTREMKSELELAKQRSGLE 1628
Query: 1664 DALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQG 1723
D L L+ K + A A+ A SAQ +A E+ L QY A+ +RK
Sbjct: 1629 DG-LSLLQTKLQRHQDHAVNAKVQAESAQHQAGSLEKEF-VELKKQY----AILQRKTST 1682
Query: 1724 VLAAQ---ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
+ + +QL+D A L + K++R+ +LE ++ + ++KA QL LE ++
Sbjct: 1683 TGLTKETLGKVKQLKDAAEKLAGDTEAKIRRITDLERKIQDLNLSRQAKADQLRILEDQV 1742
Query: 1781 RSVLQAINLQVQIYNTC 1797
++ I Q + Y C
Sbjct: 1743 VAIKNEIVEQEKKYARC 1759
>gi|62868217 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 468 bits (1204), Expect = e-131
Identities = 231/514 (44%), Positives = 304/514 (59%), Gaps = 26/514 (5%)
Query: 42 CSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARD 101
CSRG+CYP GDLLVGR L ASSTCGL P+ YC + + + KC CDSR+P
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 102 NPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAML 161
N +SHR++NV +S P R WWQS+N + V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 162 VERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEG-EVIYR 220
+ERS+DFG+TW VY+Y + DC + FP V P+ W DV C+S G +V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLN 192
Query: 221 VLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVR 280
++D IP S +IQ + +ITNLRVN TRL + P YYA+ +L ++
Sbjct: 193 LMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHP-----PSAYYAVSQLRLQ 247
Query: 281 GNCFCYGHASECAPAPGAPAHAEG--MVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
G+CFC+GHA CAP PGA A VH C+C+HNT G NCE+C FY + PWRPAE
Sbjct: 248 GSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
Query: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
+H C++C+C+GH+ +CHFD AV+ AS GGVCD C+ +T G++CE C+ ++R+
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
C SC+CDP G+ G CD V+GQC CKEHV G RC C+ GF G
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDP--------VTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
L+ ++ GC RC CN G+ PCD SG C C V G CD+C P HW L+ G
Sbjct: 420 LTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG-QG 477
Query: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
C PC CD +L PQC++ TGQC CR+ G C
Sbjct: 478 CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMC 511
Score = 416 bits (1070), Expect = e-116
Identities = 300/978 (30%), Positives = 448/978 (45%), Gaps = 111/978 (11%)
Query: 877 CVCNGHADECNTHTGACLG------------CRDHTGGEHCERCIAGFHGDPRLPYGGQ- 923
C C+GHAD C GA G C+ +T G +CERC ++ P P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 924 ---CRPCPCPEGPGSQRHF---ATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDP 976
C+ C C G HF + Q Y VC +CR G CE C +F +
Sbjct: 310 AHECQRCDC-NGHSETCHFDPAVFAASQGAYGG--VCDNCRDHTEGKNCERCQLHYFRN- 365
Query: 977 SRPGGR----CQLCECSGNIDPMDPDA------CDPHTGQCLRCLHHTEGPHCAHCKPGF 1026
RPG C CEC DPD CDP TGQC+ C H +G C CKPGF
Sbjct: 366 RRPGASIQETCISCEC-------DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGF 417
Query: 1027 HG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
G A Q CHRC CN+LG+ CD SG+C CLPNV GP CD+CAP W
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDM-------PCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Query: 1085 NLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-----ECQELHWGDPGLQ 1139
L SG GC+PCAC P + P CN+FTGQC CR GFGG CS +C + +GD
Sbjct: 471 KLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG 530
Query: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDR 1199
C ACDCD RG + P C + +G C CRPG++G RCDQC RG+ +P C CH CF +D
Sbjct: 531 CRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDA 590
Query: 1200 VVQDLAARTQRLEQRAQELQQTGVL--GAFESSFWHMQEKLGIVQGIVGARNTSAASTAQ 1257
+++ A R RL L L S + K+ ++ ++ + + AQ
Sbjct: 591 DLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQ 650
Query: 1258 LVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH 1317
+ A LRR L L+ DL +++E + L L+R L ++ +
Sbjct: 651 VASAILSLRRT-------LQGLQLDL-PLEEETLSLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1318 LDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKE 1377
+ + ++ GA+ + A+ QSA+A ++ + S+ + + L D+++E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLL--------------DQLRDSRRE 748
Query: 1378 DFNSKHMANQRALG------KLSAHTHTLS----LTDINELVCGAPGDAPCATSPCGGAG 1427
++ + Q G KL A +S LT +CG C C G
Sbjct: 749 ---AERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGEL 805
Query: 1428 CRDEDGQ---PRCGGL--SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRR 1482
C ++G RC G+ GA A + R A+LQR + R AE
Sbjct: 806 CPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-----MIRAAE--E 858
Query: 1483 QASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLE 1542
AS+ Q AQ + +ASR Q+E+ + + LIQ V+DFL D +I+ V+ VL
Sbjct: 859 SASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLA 918
Query: 1543 LSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQ 1602
L +P + + I L +VD +L++T D+ RA +L +A ARS A +
Sbjct: 919 LWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEG 978
Query: 1603 KAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQ 1662
+ E V L + A AQ ++G R + + +VQ+ + AE+ ++S ++
Sbjct: 979 QVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGD 1038
Query: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
+E L+ + A A++ A A +A A++ + +Y +K +R Q
Sbjct: 1039 FWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELK---DRLGQ 1094
Query: 1723 GVLAAQ--ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
+ + AR + ++ EA +L + + R++++E +A+ ++A L GLE R+
Sbjct: 1095 SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRV 1154
Query: 1781 RSVLQAINLQVQIYNTCQ 1798
+ IN +V Y TC+
Sbjct: 1155 EQIRDHINGRVLYYATCK 1172
Score = 146 bits (368), Expect = 2e-34
Identities = 85/232 (36%), Positives = 117/232 (50%), Gaps = 27/232 (11%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSG--GVCDGCQHNTAGRHCELCRPFFYRDPTKDL--R 402
C CHGH C VC CQHNTAG +CE C PF+ P + +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPAL-----GLVSGQC-RCKEHVVGTRCQQCRDGF 456
D C+ CDC+ G H DPA+ G G C C++H G C++C+ +
Sbjct: 309 DAHECQRCDCN------GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
Query: 457 F-----GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
F G SI + C C+C+ G VPG+ PCDP +G C CK V G CD C PG G
Sbjct: 363 FRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 512 LSH-DLLGCRPCDCDV-GGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
L++ + GC CDC++ G D CDE +G+C C ++VG +C+Q P +++
Sbjct: 420 LTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWK 471
Score = 133 bits (335), Expect = 1e-30
Identities = 77/215 (35%), Positives = 101/215 (46%), Gaps = 33/215 (15%)
Query: 776 IYNGALPCQCNPQGSL-SSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQAC 831
I + C+C+P G++ + C+P GQC+CK V G RCDLC PG+ G P GC C
Sbjct: 372 IQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRC 431
Query: 832 QCSHEGALSSL-CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS---CRPCVCNGH---AD 884
C+ G+ + C++ SG+CLC G +CD+C W S C PC C+ H +
Sbjct: 432 DCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP 491
Query: 885 ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGG---QCRPCPC----PEGPGSQR 937
+CN TG C CR+ GG C A P YG CR C C EGPG +
Sbjct: 492 QCNQFTGQC-PCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
C CR G TG RC+ C G+
Sbjct: 549 ASGR------------CLCRPGLTGPRCDQCQRGY 571
Score = 102 bits (254), Expect = 3e-21
Identities = 59/150 (39%), Positives = 73/150 (48%), Gaps = 16/150 (10%)
Query: 749 CHEEG----LVPSKTSPS-EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCL 803
C EE +P+ P + CAP L++ G PC C+P SLS +CN GQC
Sbjct: 444 CDEESGRCLCLPNVVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCP 501
Query: 804 CKPGVVGRRCDL-----CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
C+ G G C C YG TGC+AC C G C+K SG+CLCR G G
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
Query: 859 LRCDRCQRGQWG-FP---SCRPCVCNGHAD 884
RCD+CQRG +P +C PC AD
Sbjct: 562 PRCDQCQRGYCNRYPVCVACHPCFQTYDAD 591
>gi|62868215 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 468 bits (1204), Expect = e-131
Identities = 231/514 (44%), Positives = 304/514 (59%), Gaps = 26/514 (5%)
Query: 42 CSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARD 101
CSRG+CYP GDLLVGR L ASSTCGL P+ YC + + + KC CDSR+P
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 102 NPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAML 161
N +SHR++NV +S P R WWQS+N + V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 162 VERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEG-EVIYR 220
+ERS+DFG+TW VY+Y + DC + FP V P+ W DV C+S G +V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLN 192
Query: 221 VLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVR 280
++D IP S +IQ + +ITNLRVN TRL + P YYA+ +L ++
Sbjct: 193 LMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHP-----PSAYYAVSQLRLQ 247
Query: 281 GNCFCYGHASECAPAPGAPAHAEG--MVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
G+CFC+GHA CAP PGA A VH C+C+HNT G NCE+C FY + PWRPAE
Sbjct: 248 GSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
Query: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
+H C++C+C+GH+ +CHFD AV+ AS GGVCD C+ +T G++CE C+ ++R+
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
C SC+CDP G+ G CD V+GQC CKEHV G RC C+ GF G
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDP--------VTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
L+ ++ GC RC CN G+ PCD SG C C V G CD+C P HW L+ G
Sbjct: 420 LTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG-QG 477
Query: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
C PC CD +L PQC++ TGQC CR+ G C
Sbjct: 478 CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMC 511
Score = 416 bits (1070), Expect = e-116
Identities = 300/978 (30%), Positives = 448/978 (45%), Gaps = 111/978 (11%)
Query: 877 CVCNGHADECNTHTGACLG------------CRDHTGGEHCERCIAGFHGDPRLPYGGQ- 923
C C+GHAD C GA G C+ +T G +CERC ++ P P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 924 ---CRPCPCPEGPGSQRHF---ATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDP 976
C+ C C G HF + Q Y VC +CR G CE C +F +
Sbjct: 310 AHECQRCDC-NGHSETCHFDPAVFAASQGAYGG--VCDNCRDHTEGKNCERCQLHYFRN- 365
Query: 977 SRPGGR----CQLCECSGNIDPMDPDA------CDPHTGQCLRCLHHTEGPHCAHCKPGF 1026
RPG C CEC DPD CDP TGQC+ C H +G C CKPGF
Sbjct: 366 RRPGASIQETCISCEC-------DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGF 417
Query: 1027 HG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
G A Q CHRC CN+LG+ CD SG+C CLPNV GP CD+CAP W
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDM-------PCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Query: 1085 NLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-----ECQELHWGDPGLQ 1139
L SG GC+PCAC P + P CN+FTGQC CR GFGG CS +C + +GD
Sbjct: 471 KLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG 530
Query: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDR 1199
C ACDCD RG + P C + +G C CRPG++G RCDQC RG+ +P C CH CF +D
Sbjct: 531 CRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDA 590
Query: 1200 VVQDLAARTQRLEQRAQELQQTGVL--GAFESSFWHMQEKLGIVQGIVGARNTSAASTAQ 1257
+++ A R RL L L S + K+ ++ ++ + + AQ
Sbjct: 591 DLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQ 650
Query: 1258 LVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH 1317
+ A LRR L L+ DL +++E + L L+R L ++ +
Sbjct: 651 VASAILSLRRT-------LQGLQLDL-PLEEETLSLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1318 LDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKE 1377
+ + ++ GA+ + A+ QSA+A ++ + S+ + + L D+++E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLL--------------DQLRDSRRE 748
Query: 1378 DFNSKHMANQRALG------KLSAHTHTLS----LTDINELVCGAPGDAPCATSPCGGAG 1427
++ + Q G KL A +S LT +CG C C G
Sbjct: 749 ---AERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGEL 805
Query: 1428 CRDEDGQ---PRCGGL--SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRR 1482
C ++G RC G+ GA A + R A+LQR + R AE
Sbjct: 806 CPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-----MIRAAE--E 858
Query: 1483 QASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLE 1542
AS+ Q AQ + +ASR Q+E+ + + LIQ V+DFL D +I+ V+ VL
Sbjct: 859 SASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLA 918
Query: 1543 LSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQ 1602
L +P + + I L +VD +L++T D+ RA +L +A ARS A +
Sbjct: 919 LWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEG 978
Query: 1603 KAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQ 1662
+ E V L + A AQ ++G R + + +VQ+ + AE+ ++S ++
Sbjct: 979 QVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGD 1038
Query: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
+E L+ + A A++ A A +A A++ + +Y +K +R Q
Sbjct: 1039 FWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELK---DRLGQ 1094
Query: 1723 GVLAAQ--ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
+ + AR + ++ EA +L + + R++++E +A+ ++A L GLE R+
Sbjct: 1095 SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRV 1154
Query: 1781 RSVLQAINLQVQIYNTCQ 1798
+ IN +V Y TC+
Sbjct: 1155 EQIRDHINGRVLYYATCK 1172
Score = 146 bits (368), Expect = 2e-34
Identities = 85/232 (36%), Positives = 117/232 (50%), Gaps = 27/232 (11%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSG--GVCDGCQHNTAGRHCELCRPFFYRDPTKDL--R 402
C CHGH C VC CQHNTAG +CE C PF+ P + +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPAL-----GLVSGQC-RCKEHVVGTRCQQCRDGF 456
D C+ CDC+ G H DPA+ G G C C++H G C++C+ +
Sbjct: 309 DAHECQRCDCN------GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
Query: 457 F-----GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
F G SI + C C+C+ G VPG+ PCDP +G C CK V G CD C PG G
Sbjct: 363 FRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 512 LSH-DLLGCRPCDCDV-GGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
L++ + GC CDC++ G D CDE +G+C C ++VG +C+Q P +++
Sbjct: 420 LTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWK 471
Score = 133 bits (335), Expect = 1e-30
Identities = 77/215 (35%), Positives = 101/215 (46%), Gaps = 33/215 (15%)
Query: 776 IYNGALPCQCNPQGSL-SSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQAC 831
I + C+C+P G++ + C+P GQC+CK V G RCDLC PG+ G P GC C
Sbjct: 372 IQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRC 431
Query: 832 QCSHEGALSSL-CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS---CRPCVCNGH---AD 884
C+ G+ + C++ SG+CLC G +CD+C W S C PC C+ H +
Sbjct: 432 DCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP 491
Query: 885 ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGG---QCRPCPC----PEGPGSQR 937
+CN TG C CR+ GG C A P YG CR C C EGPG +
Sbjct: 492 QCNQFTGQC-PCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
C CR G TG RC+ C G+
Sbjct: 549 ASGR------------CLCRPGLTGPRCDQCQRGY 571
Score = 102 bits (254), Expect = 3e-21
Identities = 59/150 (39%), Positives = 73/150 (48%), Gaps = 16/150 (10%)
Query: 749 CHEEG----LVPSKTSPS-EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCL 803
C EE +P+ P + CAP L++ G PC C+P SLS +CN GQC
Sbjct: 444 CDEESGRCLCLPNVVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCP 501
Query: 804 CKPGVVGRRCDL-----CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
C+ G G C C YG TGC+AC C G C+K SG+CLCR G G
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
Query: 859 LRCDRCQRGQWG-FP---SCRPCVCNGHAD 884
RCD+CQRG +P +C PC AD
Sbjct: 562 PRCDQCQRGYCNRYPVCVACHPCFQTYDAD 591
>gi|189083719 laminin, beta 3 precursor [Homo sapiens]
Length = 1172
Score = 468 bits (1204), Expect = e-131
Identities = 231/514 (44%), Positives = 304/514 (59%), Gaps = 26/514 (5%)
Query: 42 CSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARD 101
CSRG+CYP GDLLVGR L ASSTCGL P+ YC + + + KC CDSR+P
Sbjct: 21 CSRGACYPPVGDLLVGRTRFLRASSTCGLTKPETYC-TQYGEWQMKCCKCDSRQPH---- 75
Query: 102 NPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTIQLDLEAEFHFTHLIMTFKTFRPAAML 161
N +SHR++NV +S P R WWQS+N + V++QLDL+ F ++M F+ PA ML
Sbjct: 76 NYYSHRVENVASSSGPMR---WWQSQNDVNPVSLQLDLDRRFQLQEVMMEFQGPMPAGML 132
Query: 162 VERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEG-EVIYR 220
+ERS+DFG+TW VY+Y + DC + FP V P+ W DV C+S G +V
Sbjct: 133 IERSSDFGKTWRVYQYLAADCTSTFPRVRQGRPQSWQDVRCQSLPQRPNARLNGGKVQLN 192
Query: 221 VLDPAIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYYYALYELVVR 280
++D IP S +IQ + +ITNLRVN TRL + P YYA+ +L ++
Sbjct: 193 LMDLVSGIPATQSQKIQEVGEITNLRVNFTRLAPVPQRGYHP-----PSAYYAVSQLRLQ 247
Query: 281 GNCFCYGHASECAPAPGAPAHAEG--MVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
G+CFC+GHA CAP PGA A VH C+C+HNT G NCE+C FY + PWRPAE
Sbjct: 248 GSCFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEG 307
Query: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
+H C++C+C+GH+ +CHFD AV+ AS GGVCD C+ +T G++CE C+ ++R+
Sbjct: 308 QDAHECQRCDCNGHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHYFRNRR 367
Query: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
C SC+CDP G+ G CD V+GQC CKEHV G RC C+ GF G
Sbjct: 368 PGASIQETCISCECDPDGAVPGAPCDP--------VTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 459 LSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
L+ ++ GC RC CN G+ PCD SG C C V G CD+C P HW L+ G
Sbjct: 420 LTYANPQGCHRCDCNILGS-RRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASG-QG 477
Query: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
C PC CD +L PQC++ TGQC CR+ G C
Sbjct: 478 CEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMC 511
Score = 416 bits (1070), Expect = e-116
Identities = 300/978 (30%), Positives = 448/978 (45%), Gaps = 111/978 (11%)
Query: 877 CVCNGHADECNTHTGACLG------------CRDHTGGEHCERCIAGFHGDPRLPYGGQ- 923
C C+GHAD C GA G C+ +T G +CERC ++ P P GQ
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCVCQHNTAGPNCERCAPFYNNRPWRPAEGQD 309
Query: 924 ---CRPCPCPEGPGSQRHF---ATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDP 976
C+ C C G HF + Q Y VC +CR G CE C +F +
Sbjct: 310 AHECQRCDC-NGHSETCHFDPAVFAASQGAYGG--VCDNCRDHTEGKNCERCQLHYFRN- 365
Query: 977 SRPGGR----CQLCECSGNIDPMDPDA------CDPHTGQCLRCLHHTEGPHCAHCKPGF 1026
RPG C CEC DPD CDP TGQC+ C H +G C CKPGF
Sbjct: 366 RRPGASIQETCISCEC-------DPDGAVPGAPCDPVTGQCV-CKEHVQGERCDLCKPGF 417
Query: 1027 HG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
G A Q CHRC CN+LG+ CD SG+C CLPNV GP CD+CAP W
Sbjct: 418 TGLTYANPQGCHRCDCNILGSRRDM-------PCDEESGRCLCLPNVVGPKCDQCAPYHW 470
Query: 1085 NLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-----ECQELHWGDPGLQ 1139
L SG GC+PCAC P + P CN+FTGQC CR GFGG CS +C + +GD
Sbjct: 471 KLASGQGCEPCACDPHNSLSPQCNQFTGQCPCREGFGGLMCSAAAIRQCPDRTYGDVATG 530
Query: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDR 1199
C ACDCD RG + P C + +G C CRPG++G RCDQC RG+ +P C CH CF +D
Sbjct: 531 CRACDCDFRGTEGPGCDKASGRCLCRPGLTGPRCDQCQRGYCNRYPVCVACHPCFQTYDA 590
Query: 1200 VVQDLAARTQRLEQRAQELQQTGVL--GAFESSFWHMQEKLGIVQGIVGARNTSAASTAQ 1257
+++ A R RL L L S + K+ ++ ++ + + AQ
Sbjct: 591 DLREQALRFGRLRNATASLWSGPGLEDRGLASRILDAKSKIEQIRAVLSSPAVTEQEVAQ 650
Query: 1258 LVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH 1317
+ A LRR L L+ DL +++E + L L+R L ++ +
Sbjct: 651 VASAILSLRRT-------LQGLQLDL-PLEEETLSLPRDLESLDRSFNGLLTMYQRKREQ 702
Query: 1318 LDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKE 1377
+ + ++ GA+ + A+ QSA+A ++ + S+ + + L D+++E
Sbjct: 703 FEKISSADPSGAFRMLSTAYEQSAQAAQQVSDSSRLL--------------DQLRDSRRE 748
Query: 1378 DFNSKHMANQRALG------KLSAHTHTLS----LTDINELVCGAPGDAPCATSPCGGAG 1427
++ + Q G KL A +S LT +CG C C G
Sbjct: 749 ---AERLVRQAGGGGGTGSPKLVALRLEMSSLPDLTPTFNKLCGNSRQMACTPISCPGEL 805
Query: 1428 CRDEDGQ---PRCGGL--SCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRR 1482
C ++G RC G+ GA A + R A+LQR + R AE
Sbjct: 806 CPQDNGTACGSRCRGVLPRAGGAFLMAGQVAEQLRGFNAQLQRTRQ-----MIRAAE--E 858
Query: 1483 QASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLE 1542
AS+ Q AQ + +ASR Q+E+ + + LIQ V+DFL D +I+ V+ VL
Sbjct: 859 SASQIQSSAQRLETQVSASRSQMEEDVRRTRLLIQQVRDFLTDPDTDAATIQEVSEAVLA 918
Query: 1543 LSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQ 1602
L +P + + I L +VD +L++T D+ RA +L +A ARS A +
Sbjct: 919 LWLPTDSATVLQKMNEIQAIAARLPNVDLVLSQTKQDIARARRLQAEAEEARSRAHAVEG 978
Query: 1603 KAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQ 1662
+ E V L + A AQ ++G R + + +VQ+ + AE+ ++S ++
Sbjct: 979 QVEDVVGNLRQGTVALQEAQDTMQGTSRSLRLIQDRVAEVQQVLRPAEKLVTSMTKQLGD 1038
Query: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
+E L+ + A A++ A A +A A++ + +Y +K +R Q
Sbjct: 1039 FWTRMEELRHQARQQGAEAVQAQQLAEGASEQALSAQEGFE-RIKQKYAELK---DRLGQ 1094
Query: 1723 GVLAAQ--ARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARM 1780
+ + AR + ++ EA +L + + R++++E +A+ ++A L GLE R+
Sbjct: 1095 SSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRV 1154
Query: 1781 RSVLQAINLQVQIYNTCQ 1798
+ IN +V Y TC+
Sbjct: 1155 EQIRDHINGRVLYYATCK 1172
Score = 146 bits (368), Expect = 2e-34
Identities = 85/232 (36%), Positives = 117/232 (50%), Gaps = 27/232 (11%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSG--GVCDGCQHNTAGRHCELCRPFFYRDPTKDL--R 402
C CHGH C VC CQHNTAG +CE C PF+ P + +
Sbjct: 250 CFCHGHADRCAPKPGASAGPSTAVQVHDVCV-CQHNTAGPNCERCAPFYNNRPWRPAEGQ 308
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPAL-----GLVSGQC-RCKEHVVGTRCQQCRDGF 456
D C+ CDC+ G H DPA+ G G C C++H G C++C+ +
Sbjct: 309 DAHECQRCDCN------GHSETCHFDPAVFAASQGAYGGVCDNCRDHTEGKNCERCQLHY 362
Query: 457 F-----GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
F G SI + C C+C+ G VPG+ PCDP +G C CK V G CD C PG G
Sbjct: 363 FRNRRPGASIQET--CISCECDPDGAVPGA-PCDPVTGQCVCKEHVQGERCDLCKPGFTG 419
Query: 512 LSH-DLLGCRPCDCDV-GGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
L++ + GC CDC++ G D CDE +G+C C ++VG +C+Q P +++
Sbjct: 420 LTYANPQGCHRCDCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWK 471
Score = 133 bits (335), Expect = 1e-30
Identities = 77/215 (35%), Positives = 101/215 (46%), Gaps = 33/215 (15%)
Query: 776 IYNGALPCQCNPQGSL-SSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQAC 831
I + C+C+P G++ + C+P GQC+CK V G RCDLC PG+ G P GC C
Sbjct: 372 IQETCISCECDPDGAVPGAPCDPVTGQCVCKEHVQGERCDLCKPGFTGLTYANPQGCHRC 431
Query: 832 QCSHEGALSSL-CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS---CRPCVCNGH---AD 884
C+ G+ + C++ SG+CLC G +CD+C W S C PC C+ H +
Sbjct: 432 DCNILGSRRDMPCDEESGRCLCLPNVVGPKCDQCAPYHWKLASGQGCEPCACDPHNSLSP 491
Query: 885 ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGG---QCRPCPC----PEGPGSQR 937
+CN TG C CR+ GG C A P YG CR C C EGPG +
Sbjct: 492 QCNQFTGQC-PCREGFGGLMCS--AAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDK 548
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
C CR G TG RC+ C G+
Sbjct: 549 ASGR------------CLCRPGLTGPRCDQCQRGY 571
Score = 102 bits (254), Expect = 3e-21
Identities = 59/150 (39%), Positives = 73/150 (48%), Gaps = 16/150 (10%)
Query: 749 CHEEG----LVPSKTSPS-EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCL 803
C EE +P+ P + CAP L++ G PC C+P SLS +CN GQC
Sbjct: 444 CDEESGRCLCLPNVVGPKCDQCAPYHWKLAS--GQGCEPCACDPHNSLSPQCNQFTGQCP 501
Query: 804 CKPGVVGRRCDL-----CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
C+ G G C C YG TGC+AC C G C+K SG+CLCR G G
Sbjct: 502 CREGFGGLMCSAAAIRQCPDRTYGDVATGCRACDCDFRGTEGPGCDKASGRCLCRPGLTG 561
Query: 859 LRCDRCQRGQWG-FP---SCRPCVCNGHAD 884
RCD+CQRG +P +C PC AD
Sbjct: 562 PRCDQCQRGYCNRYPVCVACHPCFQTYDAD 591
>gi|93204871 netrin 4 [Homo sapiens]
Length = 628
Score = 358 bits (919), Expect = 3e-98
Identities = 198/488 (40%), Positives = 268/488 (54%), Gaps = 51/488 (10%)
Query: 23 LLSVLAATLAQAPAPDVPGCS---RGSCYPATGDLLVGRADRLTASSTCGLNGPQPYCIV 79
LL + T+ A V G S +C P G+L +GR +L A +TCG N + YC
Sbjct: 7 LLLLWGCTVVAAGLSGVAGVSSRCEKACNPRMGNLALGR--KLWADTTCGQNATELYCFY 64
Query: 80 SHLQD----EKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPAVTI 135
S D + KC C++ P H + + + + + WWQS + I
Sbjct: 65 SENTDLTCRQPKCDKCNAAYP-------HLAHLPSAMADSSFRFPRTWWQSAEDVHREKI 117
Query: 136 QLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPR 195
QLDLEAEF+FTHLI+ FK+ RPAAM+++RS DFG+TW Y+YF+ +C A F G+
Sbjct: 118 QLDLEAEFYFTHLIVMFKSPRPAAMVLDRSQDFGKTWKPYKYFATNCSATF-GLE----- 171
Query: 196 HWDDVV-----CESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLLKITNLRVNLT 250
DDVV C S+YS P T GEVI++ L P +PYS+++Q LKITNLRV L
Sbjct: 172 --DDVVKKGAICTSKYSSPFPCTGGEVIFKALSPPYDTENPYSAKVQEQLKITNLRVQLL 229
Query: 251 RLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPG-APAHAEG---MV 306
+ + D E + +YA+Y+ +V+G+CFC GHA +C P G P A G MV
Sbjct: 230 KRQSCPCQRNDLNEEPQHFTHYAIYDFIVKGSCFCNGHADQCIPVHGFRPVKAPGTFHMV 289
Query: 307 HGACICKHNTRGLNCEQCQDFYRDLPWRPAED--GHSHACRKCECHGHTHSCHFDMAVYL 364
HG C+CKHNT G +C+ C Y D PW A+ G + CR C+C+GH +CHFD+ V+
Sbjct: 290 HGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWE 349
Query: 365 ASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQD-GGRC 423
ASGN SGGVCD CQHNT G++C+ C+P FYRD + P C+ C C P+GS
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANS 409
Query: 424 DSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP 483
+ DP+ +G C CK V G RC +C G++G GCR C C +
Sbjct: 410 VTFCDPS----NGDCPCKPGVAGRRCDRCMVGYWGFG---DYGCRPCDC--------AGS 454
Query: 484 CDPNSGSC 491
CDP +G C
Sbjct: 455 CDPITGDC 462
Score = 110 bits (276), Expect = 9e-24
Identities = 61/183 (33%), Positives = 84/183 (45%), Gaps = 35/183 (19%)
Query: 954 CHCRAGYTGLRCEACAP-----------GHFGDPSRPGGRCQLCECSGNIDPMDPD---- 998
C C+ G C+ CAP G G P+ C+ C+C+G+ D D
Sbjct: 293 CMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE----CRTCKCNGHADTCHFDVNVW 348
Query: 999 --ACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR-----QSCHRCTCNLLGTNPQQCP 1051
+ + G C C H+TEG +C CKPGF+ R +C C+C+ +G+ P
Sbjct: 349 EASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGS--AVLP 406
Query: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFT 1111
+ CDPS+G CPC P V G CDRC +W +GC+PC C S C+ T
Sbjct: 407 ANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGF-GDYGCRPCDCAGS------CDPIT 459
Query: 1112 GQC 1114
G C
Sbjct: 460 GDC 462
Score = 103 bits (258), Expect = 1e-21
Identities = 71/237 (29%), Positives = 95/237 (40%), Gaps = 61/237 (25%)
Query: 800 GQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGL 859
G C C D C P +GF P G+C+C+ G
Sbjct: 260 GSCFCNG-----HADQCIP-VHGFRPVKAPGT-----------FHMVHGKCMCKHNTAGS 302
Query: 860 RCDRCQR-----------GQWGFPS-CRPCVCNGHADEC-----------NTHTGACLGC 896
C C G+ G P+ CR C CNGHAD C N G C C
Sbjct: 303 HCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDC 362
Query: 897 RDHTGGEHCERCIAGFHGDPRLPYGG--QCRPCPC-PEG----PGSQRHFATSCHQDEYS 949
+ +T G++C+RC GF+ D R P+ C+PC C P G P + F + D
Sbjct: 363 QHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGD--- 419
Query: 950 QQIVCHCRAGYTGLRCEACAPGH--FGDPSRPGGRCQLCECSGNIDPMDPDACDPHT 1004
C C+ G G RC+ C G+ FGD C+ C+C+G+ DP+ D HT
Sbjct: 420 ----CPCKPGVAGRRCDRCMVGYWGFGDYG-----CRPCDCAGSCDPITGDCISSHT 467
Score = 95.5 bits (236), Expect = 4e-19
Identities = 64/217 (29%), Positives = 81/217 (37%), Gaps = 56/217 (25%)
Query: 986 CECSGNIDPMDP-----DACDPHT-----GQCLRCLHHTEGPHCAHCKPGFHGQ------ 1029
C C+G+ D P P T G+C+ C H+T G HC HC P ++ +
Sbjct: 262 CFCNGHADQCIPVHGFRPVKAPGTFHMVHGKCM-CKHNTAGSHCQHCAPLYNDRPWEAAD 320
Query: 1030 ---AARQSCHRCTCNLLGTNPQQCPSPDQCHCDP---------SSGQCP-CLPNVQGPSC 1076
A C C CN D CH D S G C C N +G C
Sbjct: 321 GKTGAPNECRTCKCN---------GHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYC 371
Query: 1077 DRCAPNFWN-----LTSGHGCQPCACHPSRARGPTCNEFT------GQCHCRAGFGGRTC 1125
RC P F+ ++ C+PC+CHP + N T G C C+ G GR C
Sbjct: 372 QRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRC 431
Query: 1126 SECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHC 1162
C +WG C CDC C TG C
Sbjct: 432 DRCMVGYWGFGDYGCRPCDC------AGSCDPITGDC 462
Score = 77.8 bits (190), Expect = 9e-14
Identities = 45/140 (32%), Positives = 59/140 (42%), Gaps = 26/140 (18%)
Query: 778 NGALPCQCNPQGSL--------SSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG------ 822
N C+CN + N GG C C+ G+ C C PG+Y
Sbjct: 327 NECRTCKCNGHADTCHFDVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPF 386
Query: 823 FGPTGCQACQCSHEGALS------SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP--SC 874
P C+ C C G+ + C+ ++G C C+ G G RCDRC G WGF C
Sbjct: 387 SAPDACKPCSCHPVGSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGC 446
Query: 875 RPCVCNGHADECNTHTGACL 894
RPC C G C+ TG C+
Sbjct: 447 RPCDCAG---SCDPITGDCI 463
Score = 68.2 bits (165), Expect = 7e-11
Identities = 47/159 (29%), Positives = 64/159 (40%), Gaps = 38/159 (23%)
Query: 433 LVSGQCRCKEHVVGTRCQQCR-----------DGFFGLSISDRLGCRRCQCNARGTV--- 478
+V G+C CK + G+ CQ C DG G CR C+CN
Sbjct: 288 MVHGKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNE----CRTCKCNGHADTCHF 343
Query: 479 ---PGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSHDLL-------GCRPCDCD-V 526
+ + G C C+ G+ C RC PG + DL C+PC C V
Sbjct: 344 DVNVWEASGNRSGGVCDDCQHNTEGQYCQRCKPGFY---RDLRRPFSAPDACKPCSCHPV 400
Query: 527 GGALDPQ-----CDEGTGQCHCRQHMVGRRCEQVQPGYF 560
G A+ P CD G C C+ + GRRC++ GY+
Sbjct: 401 GSAVLPANSVTFCDPSNGDCPCKPGVAGRRCDRCMVGYW 439
Score = 67.4 bits (163), Expect = 1e-10
Identities = 48/172 (27%), Positives = 58/172 (33%), Gaps = 32/172 (18%)
Query: 1063 GQCPCLPNVQGPSCDRCAPNF----WNLTSGHGCQPCACHPSRARG--PTCNEFTGQCHC 1116
G+C C N G C CAP + W G P C + G TC+
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCNGHADTCHFDVNVWEA 350
Query: 1117 RAGFGGRTCSECQELHWGD------PGLQ------------CHACDCDSRGI------DT 1152
G C +CQ G PG C C C G
Sbjct: 351 SGNRSGGVCDDCQHNTEGQYCQRCKPGFYRDLRRPFSAPDACKPCSCHPVGSAVLPANSV 410
Query: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP-ACHPCHACFGDWDRVVQD 1203
C G C C+PGV+G RCD+C G+ G C PC C G D + D
Sbjct: 411 TFCDPSNGDCPCKPGVAGRRCDRCMVGYWGFGDYGCRPCD-CAGSCDPITGD 461
Score = 36.2 bits (82), Expect = 0.30
Identities = 26/91 (28%), Positives = 38/91 (41%), Gaps = 19/91 (20%)
Query: 489 GSCYCKRLVTGRGCDRCLPGH----WGLSHDLLG----CRPCDCDVGGA----LDPQCDE 536
G C CK G C C P + W + G CR C C+ G A D E
Sbjct: 291 GKCMCKHNTAGSHCQHCAPLYNDRPWEAADGKTGAPNECRTCKCN-GHADTCHFDVNVWE 349
Query: 537 GTGQ-----CH-CRQHMVGRRCEQVQPGYFR 561
+G C C+ + G+ C++ +PG++R
Sbjct: 350 ASGNRSGGVCDDCQHNTEGQYCQRCKPGFYR 380
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 306 bits (784), Expect = 1e-82
Identities = 253/980 (25%), Positives = 411/980 (41%), Gaps = 127/980 (12%)
Query: 850 CLCRTGAFGLRCDRCQRGQ-------WGFPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902
C C G G C+ C G + C C CNGH++ C+ TG C CRD+T G
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVC-NCRDNTAG 748
Query: 903 EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYT 961
HCE+C G++GD C+PCPCP G +SC ++++VC +C G T
Sbjct: 749 PHCEKCSDGYYGDSTAGTSSDCQPCPCPGG--------SSCAVVPKTKEVVCTNCPTGTT 800
Query: 962 GLRCEACAPGHFGDP---SRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPH 1018
G RCE C G+FGDP + P C+LC+CS NIDP C+ TG+CL+C+++T G +
Sbjct: 801 GKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGECLKCIYNTAGFY 860
Query: 1019 CAHCKPGFHGQAARQS----CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
C CK GF G + C C CNL GT QQ C+P +GQC CLP+V G
Sbjct: 861 CDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSS------CNPVTGQCECLPHVTGQ 914
Query: 1075 SCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG 1134
C C P F+NL SG GC+ C CH + C+ TGQC C+ G G+ C C+ H+G
Sbjct: 915 DCGACDPGFYNLQSGQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFG 974
Query: 1135 DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG--FSGIFPACHPCHA 1192
C CDC G + QC + G C CR G G RCDQC ++ +P C C A
Sbjct: 975 FGPEGCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPA 1033
Query: 1193 CFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGARNTSA 1252
C+ V D + Q LE L TG + +F +++L + V A
Sbjct: 1034 CYRLVKDKVADHRVKLQELESLIANL-GTGDEMVTDQAF---EDRLKEAEREVMDLLREA 1089
Query: 1253 ASTAQLVE-ATEELRREIGEATEHLTQLEADLTDVQDENFNANHALSGLERDRLALNLTL 1311
+ + + L+R + +++L+ +++ A A + +E + +
Sbjct: 1090 QDVKDVDQNLMDRLQRVNNTLSSQISRLQNIRNTIEETGNLAEQARAHVENTERLIEIAS 1149
Query: 1312 RQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEA- 1370
R+L++ + A+ + E + + + + + + + RH+ EA
Sbjct: 1150 RELEK--------------AKVAAANVSVTQPESTGDPNNMTLLAEEARKLAERHKQEAD 1195
Query: 1371 -LMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCR 1429
++ K ++ A L L+ T +I EL
Sbjct: 1196 DIVRVAKTANDTSTEAYNLLLRTLAGENQT--AFEIEEL--------------------N 1233
Query: 1430 DEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQQ 1489
+ Q + AA RA E+ ++A+ + S E +A+ +
Sbjct: 1234 RKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLE--NEANNIKM 1291
Query: 1490 RAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASA 1549
A+ + E ++++ VK+ L + + + + + R A
Sbjct: 1292 EAENLEQLIDQKLKDYEDLREDMRGKELEVKNLLEKGKTEQQTADQLLAR---------A 1342
Query: 1550 EQIQHLAGAIAERVR-SLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQ 1608
+ + LA A++ R +L + + IL +++ ++ + D + A AE+ +K +
Sbjct: 1343 DAAKALAEEAAKKGRDTLQEANDIL----NNLKDFDRRVNDNKTA---AEEALRKIPAIN 1395
Query: 1609 AALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGA--ERALSSAGERARQLDAL 1666
+ EA AQ A+ A AD + + ++ ER+A A + A S+ E R
Sbjct: 1396 QTITEANEKTREAQQALGSAAADATEAKNKAHEA-ERIASAVQKNATSTKAEAER---TF 1451
Query: 1667 LEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLA 1726
E L N++ + QEAE+ L+ D Q + +A +Q
Sbjct: 1452 AEVTDLDNEVNNMLK------------QLQEAEKELKRKQDDADQDM-MMAGMASQAAQE 1498
Query: 1727 AQARAEQLRDEARDLLQAAQDKLQ-----------RLQELEGTYEENERALESKAAQLDG 1775
A+ A + ++ LL D L+ +L E+EGT N+ E K + LD
Sbjct: 1499 AEINARKAKNSVTSLLSIINDLLEQLGQLDTVDLNKLNEIEGTL--NKAKDEMKVSDLDR 1556
Query: 1776 LEARMRSVLQAINLQVQIYN 1795
+ + + + + YN
Sbjct: 1557 KVSDLENEAKKQEAAIMDYN 1576
Score = 267 bits (683), Expect = 6e-71
Identities = 179/539 (33%), Positives = 256/539 (47%), Gaps = 73/539 (13%)
Query: 6 RERGRGQPLPWELRLGLLLSVLAATLAQAPAPDVP--GCSRGSCYPATGDLLVGRADRLT 63
R RGR P+ L +L + AA AQA + G C P V A +T
Sbjct: 12 RPRGRLWPV-----LAVLAAAAAAGCAQAAMDECTDEGGRPQRCMPE----FVNAAFNVT 62
Query: 64 --ASSTCGLNGPQPYCIVSHLQD-EKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRR 120
A++TCG P+ YC+ + + K C LCD+ +P H +T + Q
Sbjct: 63 VVATNTCG-TPPEEYCVQTGVTGVTKSCHLCDAGQP-------HLQHGAAFLTDYNNQAD 114
Query: 121 AAWWQSENGIPAV------TIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHV 174
WWQS+ + V + L L F T++ + F T RP + + + W
Sbjct: 115 TTWWQSQTMLAGVQYPSSINLTLHLGKAFDITYVRLKFHTSRPESFAIYKRTREDGPWIP 174
Query: 175 YRYFSYDCGADFPGVPLAPPRHWDD---VVCESRYSEIEPSTEGEVIYRVLDPAIPIPDP 231
Y+Y+S C + R D +C +S+I P T G V + L+ P
Sbjct: 175 YQYYSGSCENTYSKANRGFIRTGGDEQQALCTDEFSDISPLTGGNVAFSTLEGR---PSA 231
Query: 232 Y----SSRIQNLLKITNLRVNLTRLHTLGDNLL-DPRREIREKYYYALYELVVRGNCFCY 286
Y S +Q + T++RV L RL+T GD + DP+ + + YYYA+ + V G C C
Sbjct: 232 YNFDNSPVLQEWVTATDIRVTLNRLNTFGDEVFNDPK--VLKSYYYAISDFAVGGRCKCN 289
Query: 287 GHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRK 346
GHASEC + +V C CKHNT G++CE+C F+ D PWR A + C
Sbjct: 290 GHASECMKN-----EFDKLV---CNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLP 341
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
C+C+G + C+FD +Y ++G+ GG C CQ NT G HCE CR F+R L +
Sbjct: 342 CDCNGRSQECYFDPELYRSTGH--GGHCTNCQDNTDGAHCERCRENFFR-----LGNNEA 394
Query: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG 466
C SC C P+GS +CDS+ G+C CK V+G +C +C+ GF L+ G
Sbjct: 395 CSSCHCSPVGSL-STQCDSY---------GRCSCKPGVMGDKCDRCQPGFHSLT---EAG 441
Query: 467 CRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDC 524
CR C C+ G++ C+ +G C CK V G C+RC PG + L S + GC PC C
Sbjct: 442 CRPCSCDPSGSI---DECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFC 497
Score = 203 bits (517), Expect = 1e-51
Identities = 121/370 (32%), Positives = 159/370 (42%), Gaps = 53/370 (14%)
Query: 802 CLCKPGVVGRRCDLCAPGYY----GFGP-TGCQACQCSHEGALSSLCEKTSGQCLCRTGA 856
C C G G+ C++C GY GP + C C C+ S C+ +G C CR
Sbjct: 690 CTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGH---SETCDPETGVCNCRDNT 746
Query: 857 FGLRCDRCQRGQWG------FPSCRPCVCNGHADEC----NTHTGACLGCRDHTGGEHCE 906
G C++C G +G C+PC C G C T C C T G+ CE
Sbjct: 747 AGPHCEKCSDGYYGDSTAGTSSDCQPCPCPG-GSSCAVVPKTKEVVCTNCPTGTTGKRCE 805
Query: 907 RCIAGFHGDPRLPYG--GQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHCRAG 959
C G+ GDP G CR C C P G+ C C
Sbjct: 806 LCDDGYFGDPLGRNGPVRLCRLCQCSDNIDPNAVGNCNRLTGEC----------LKCIYN 855
Query: 960 YTGLRCEACAPGHFGDP--SRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
G C+ C G FG+P P +C+ C C+ +C+P TGQC CL H G
Sbjct: 856 TAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQQSSCNPVTGQC-ECLPHVTGQ 914
Query: 1018 HCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCD 1077
C C PGF+ + Q C RC C+ LG+ Q CD +GQC C P + G C+
Sbjct: 915 DCGACDPGFYNLQSGQGCERCDCHALGSTNGQ--------CDIRTGQCECQPGITGQHCE 966
Query: 1078 RCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGD-- 1135
RC N + GC+PC CHP + C + G+C CR GF G C +C+E ++ +
Sbjct: 967 RCEVNHFGF-GPEGCKPCDCHPEGSLSLQCKD-DGRCECREGFVGNRCDQCEENYFYNRS 1024
Query: 1136 -PGLQ-CHAC 1143
PG Q C AC
Sbjct: 1025 WPGCQECPAC 1034
Score = 164 bits (416), Expect = 6e-40
Identities = 114/352 (32%), Positives = 150/352 (42%), Gaps = 64/352 (18%)
Query: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG----CQACQ 832
Y+ + C CN S C+P G C C+ G C+ C+ GYYG G CQ C
Sbjct: 718 YSPCVLCACNGH---SETCDPETGVCNCRDNTAGPHCEKCSDGYYGDSTAGTSSDCQPCP 774
Query: 833 CSHEGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP--------SCRPCVCNGHA 883
C + + + + C C TG G RC+ C G +G P CR C C+ +
Sbjct: 775 CPGGSSCAVVPKTKEVVCTNCPTGTTGKRCELCDDGYFGDPLGRNGPVRLCRLCQCSDNI 834
Query: 884 D-----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY-GGQCRPCPCP-EGPGSQ 936
D CN TG CL C +T G +C+RC GF G+P P +C+ C C G Q
Sbjct: 835 DPNAVGNCNRLTGECLKCIYNTAGFYCDRCKDGFFGNPLAPNPADKCKACNCNLYGTMKQ 894
Query: 937 RHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECS--GNIDP 994
+ +SC+ C C TG C AC PG + S G C+ C+C G+ +
Sbjct: 895 Q---SSCNPVTGQ----CECLPHVTGQDCGACDPGFYNLQSGQG--CERCDCHALGSTN- 944
Query: 995 MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPD 1054
CD TGQC C+PG G Q C RC N G P+ C P
Sbjct: 945 ---GQCDIRTGQC-------------ECQPGITG----QHCERCEVNHFGFGPEGC-KPC 983
Query: 1055 QCHCDPS-------SGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPC-ACH 1098
CH + S G+C C G CD+C N++ S GCQ C AC+
Sbjct: 984 DCHPEGSLSLQCKDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQECPACY 1035
Score = 163 bits (412), Expect = 2e-39
Identities = 94/282 (33%), Positives = 133/282 (47%), Gaps = 36/282 (12%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C GH+ C P G C C+ NT G +CE+C D Y + + G S
Sbjct: 724 CACNGHSETCDPETGV-----------CNCRDNTAGPHCEKCSDGY----YGDSTAGTSS 768
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
C+ C C G + SC AV + V VC C T G+ CELC ++ DP
Sbjct: 769 DCQPCPCPGGS-SC----AVVPKTKEV---VCTNCPTGTTGKRCELCDDGYFGDPLGRNG 820
Query: 403 DPAVCRSCDC-DPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLS 460
+CR C C D + G C+ ++G+C +C + G C +C+DGFFG
Sbjct: 821 PVRLCRLCQCSDNIDPNAVGNCNR--------LTGECLKCIYNTAGFYCDRCKDGFFGNP 872
Query: 461 ISDRLG--CRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG 518
++ C+ C CN GT+ + C+P +G C C VTG+ C C PG + L G
Sbjct: 873 LAPNPADKCKACNCNLYGTMKQQSSCNPVTGQCECLPHVTGQDCGACDPGFYNLQSG-QG 931
Query: 519 CRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
C CDC G+ + QCD TGQC C+ + G+ CE+ + +F
Sbjct: 932 CERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHF 973
Score = 134 bits (338), Expect = 6e-31
Identities = 79/224 (35%), Positives = 114/224 (50%), Gaps = 35/224 (15%)
Query: 346 KCECHGHTHSC---HFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK--D 400
+C+C+GH C FD V C+ C+HNT G CE C PFF P +
Sbjct: 285 RCKCNGHASECMKNEFDKLV-----------CN-CKHNTYGVDCEKCLPFFNDRPWRRAT 332
Query: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQ----CRCKEHVVGTRCQQCRDGF 456
+ C CDC+ G + + DP L +G C+++ G C++CR+ F
Sbjct: 333 AESASECLPCDCN------GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENF 386
Query: 457 FGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516
F L ++ C C C+ G++ ST CD + G C CK V G CDRC PG L+
Sbjct: 387 FRLGNNE--ACSSCHCSPVGSL--STQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTE-- 439
Query: 517 LGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
GCRPC CD G++D +C+ TG+C C+ ++ G CE+ +PG+F
Sbjct: 440 AGCRPCSCDPSGSID-ECNIETGRCVCKDNVEGFNCERCKPGFF 482
Score = 123 bits (309), Expect = 1e-27
Identities = 66/199 (33%), Positives = 94/199 (47%), Gaps = 21/199 (10%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSR-----PGGRCQLCECSGNIDP 994
A+ C ++E+ + +VC+C+ G+ CE C P P R C C+C+G
Sbjct: 292 ASECMKNEFDK-LVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCNGRSQE 350
Query: 995 --MDPDA--CDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQC 1050
DP+ H G C C +T+G HC C+ F ++C C C+ +G+ QC
Sbjct: 351 CYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACSSCHCSPVGSLSTQC 410
Query: 1051 PSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEF 1110
S G+C C P V G CDRC P F +LT GC+PC+C PS + CN
Sbjct: 411 ---------DSYGRCSCKPGVMGDKCDRCQPGFHSLTEA-GCRPCSCDPSGSI-DECNIE 459
Query: 1111 TGQCHCRAGFGGRTCSECQ 1129
TG+C C+ G C C+
Sbjct: 460 TGRCVCKDNVEGFNCERCK 478
Score = 112 bits (280), Expect = 3e-24
Identities = 68/237 (28%), Positives = 96/237 (40%), Gaps = 41/237 (17%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLR---------CLHHTEGPHCAHCKPGFHGQA 1030
GGRC+ C+ H +C++ C H+T G C C P F+ +
Sbjct: 283 GGRCK---------------CNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRP 327
Query: 1031 ARQS-------CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQGPSCDRCAPN 1082
R++ C C CN G + + P+ G C C N G C+RC N
Sbjct: 328 WRRATAESASECLPCDCN--GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCREN 385
Query: 1083 FWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHA 1142
F+ L + C C C P + C+ + G+C C+ G G C CQ C
Sbjct: 386 FFRLGNNEACSSCHCSPVGSLSTQCDSY-GRCSCKPGVMGDKCDRCQPGFHSLTEAGCRP 444
Query: 1143 CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPA----CHPCHACFG 1195
C CD G +C+ TG C C+ V G C++C GF + + C PC CFG
Sbjct: 445 CSCDPSG-SIDECNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCF-CFG 499
Score = 111 bits (277), Expect = 7e-24
Identities = 64/165 (38%), Positives = 83/165 (50%), Gaps = 23/165 (13%)
Query: 781 LPCQCNPQGSLSSEC---------NPHGGQCL-CKPGVVGRRCDLCAPGYYGFGPT-GCQ 829
LPC CN + S EC HGG C C+ G C+ C ++ G C
Sbjct: 340 LPCDCNGR---SQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFRLGNNEACS 396
Query: 830 ACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPCVC--NGHADE 885
+C CS G+LS+ C+ + G+C C+ G G +CDRCQ G CRPC C +G DE
Sbjct: 397 SCHCSPVGSLSTQCD-SYGRCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE 455
Query: 886 CNTHTGACLGCRDHTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
CN TG C+ C+D+ G +CERC GF + P G C PC C
Sbjct: 456 CNIETGRCV-CKDNVEGFNCERCKPGFFNLESSNPRG--CTPCFC 497
Score = 108 bits (271), Expect = 4e-23
Identities = 79/255 (30%), Positives = 105/255 (41%), Gaps = 56/255 (21%)
Query: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRC----QRGQW------GFPSCRPCVCN 880
C+C+ + E C C+ +G+ C++C W C PC CN
Sbjct: 286 CKCNGHASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRRATAESASECLPCDCN 345
Query: 881 GHADEC---------NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-P 930
G + EC H G C C+D+T G HCERC F RL C C C P
Sbjct: 346 GRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFF---RLGNNEACSSCHCSP 402
Query: 931 EGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSG 990
G +T C D Y + C C+ G G +C+ C PG F + G R C+ SG
Sbjct: 403 VG-----SLSTQC--DSYGR---CSCKPGVMGDKCDRCQPG-FHSLTEAGCRPCSCDPSG 451
Query: 991 NIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQC 1050
+I D C+ TG+C+ C + EG +C CKPGF NL +NP+ C
Sbjct: 452 SI-----DECNIETGRCV-CKDNVEGFNCERCKPGFF-------------NLESSNPRGC 492
Query: 1051 PSPDQCHCDPSSGQC 1065
C C S C
Sbjct: 493 ---TPCFCFGHSSVC 504
Score = 107 bits (266), Expect = 1e-22
Identities = 44/114 (38%), Positives = 65/114 (57%), Gaps = 7/114 (6%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSL 842
C C+P GSLS++C+ +G +C CKPGV+G +CD C PG++ GC+ C C G++
Sbjct: 398 CHCSPVGSLSTQCDSYG-RCSCKPGVMGDKCDRCQPGFHSLTEAGCRPCSCDPSGSIDE- 455
Query: 843 CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS-----CRPCVCNGHADECNTHTG 891
C +G+C+C+ G C+RC+ G + S C PC C GH+ C G
Sbjct: 456 CNIETGRCVCKDNVEGFNCERCKPGFFNLESSNPRGCTPCFCFGHSSVCTNAVG 509
Score = 102 bits (254), Expect = 3e-21
Identities = 46/117 (39%), Positives = 66/117 (56%), Gaps = 6/117 (5%)
Query: 764 ACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF 823
AC P +L + G C C+ GS + +C+ GQC C+PG+ G+ C+ C ++GF
Sbjct: 918 ACDPGFYNLQS--GQGCERCDCHALGSTNGQCDIRTGQCECQPGITGQHCERCEVNHFGF 975
Query: 824 GPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQW---GFPSCRPC 877
GP GC+ C C EG+LS C K G+C CR G G RCD+C+ + +P C+ C
Sbjct: 976 GPEGCKPCDCHPEGSLSLQC-KDDGRCECREGFVGNRCDQCEENYFYNRSWPGCQEC 1031
Score = 61.6 bits (148), Expect = 7e-09
Identities = 33/89 (37%), Positives = 43/89 (48%), Gaps = 10/89 (11%)
Query: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYG 822
+ C P SL+ G PC C+P GS+ ECN G+C+CK V G C+ C PG++
Sbjct: 428 DRCQPGFHSLTEA---GCRPCSCDPSGSI-DECNIETGRCVCKDNVEGFNCERCKPGFFN 483
Query: 823 F---GPTGCQACQCSHEGALSSLCEKTSG 848
P GC C C SS+C G
Sbjct: 484 LESSNPRGCTPCFCFGH---SSVCTNAVG 509
Score = 46.6 bits (109), Expect = 2e-04
Identities = 23/71 (32%), Positives = 32/71 (45%)
Query: 490 SCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVG 549
SC C G+ C+ CL G+ + +L PC CD TG C+CR + G
Sbjct: 689 SCTCPVGYGGQFCEMCLSGYRRETPNLGPYSPCVLCACNGHSETCDPETGVCNCRDNTAG 748
Query: 550 RRCEQVQPGYF 560
CE+ GY+
Sbjct: 749 PHCEKCSDGYY 759
Score = 45.4 bits (106), Expect = 5e-04
Identities = 20/65 (30%), Positives = 29/65 (44%), Gaps = 5/65 (7%)
Query: 292 CAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHG 351
C+ P + G C+CK N G NCE+C+ + +L E + C C C G
Sbjct: 445 CSCDPSGSIDECNIETGRCVCKDNVEGFNCERCKPGFFNL-----ESSNPRGCTPCFCFG 499
Query: 352 HTHSC 356
H+ C
Sbjct: 500 HSSVC 504
Score = 44.3 bits (103), Expect = 0.001
Identities = 33/118 (27%), Positives = 48/118 (40%), Gaps = 21/118 (17%)
Query: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGS---CYCKRLVTGRGCDRCLPGH----W-- 510
+ISD RC+CN ++ C N C CK G C++CLP W
Sbjct: 276 AISDFAVGGRCKCNGH-----ASECMKNEFDKLVCNCKHNTYGVDCEKCLPFFNDRPWRR 330
Query: 511 GLSHDLLGCRPCDCDVGGA---LDPQCDEGTGQ----CHCRQHMVGRRCEQVQPGYFR 561
+ C PCDC+ DP+ TG +C+ + G CE+ + +FR
Sbjct: 331 ATAESASECLPCDCNGRSQECYFDPELYRSTGHGGHCTNCQDNTDGAHCERCRENFFR 388
>gi|21264602 laminin alpha 5 [Homo sapiens]
Length = 3695
Score = 305 bits (782), Expect = 2e-82
Identities = 381/1505 (25%), Positives = 558/1505 (37%), Gaps = 292/1505 (19%)
Query: 340 HSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK 399
+++ R C CH ++ + GG C C + GR C C ++ P
Sbjct: 1431 YNNGARPCGCH--------EVGATGPTCEPFGGQCP-CHAHVIGRDCSRCATGYWGFPN- 1480
Query: 400 DLRDPAVCRSCDCDPMGSQDGGR-CDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
CR CDC G R CD ++GQC C + C C+ FG
Sbjct: 1481 -------CRPCDC-------GARLCDE--------LTGQCICPPRTIPPDCLLCQPQTFG 1518
Query: 459 LSISDRLGCRRCQCNARGTVPGSTP-CDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517
+GC C C+ G + P CD +SG C C+ VTGR CD C PG G
Sbjct: 1519 CH--PLVGCEECNCSGPGIQELTDPTCDTDSGQCKCRPNVTGRRCDTCSPGFHGYPR--- 1573
Query: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF-----------RPFL-- 564
CRPCDC G CD TGQC+C++++ G +C+Q G F R F
Sbjct: 1574 -CRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQCSLGTFSLDAANPKGCTRCFCFG 1632
Query: 565 --------DHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVP 616
+ E D G VL +R V P E G+ +R L + +VP
Sbjct: 1633 ATERCRSSSYTRQEFVDMEGWVLLSTDRQVVPHERQP--GTEMLRAD----LRHVPEAVP 1686
Query: 617 KAMDYDLLLRLEPQVPEQWAELELIVQRPGPVPAHSLCGH------LVPKDDRIQGTLQP 670
+A L Q P + L V G + L VP + R LQ
Sbjct: 1687 EAFP-----ELYWQAPPSY--LGDRVSSYGGTLRYELHSETQRGDVFVPMESRPDVVLQG 1739
Query: 671 HARYLIFPNPVCLEPGISYKLHLKLVRTGGSAQPETPYS-GPGLLIDSLVLLPRVLVLEM 729
+ + F P PG ++ L+LV G ET + L+ L L ++ + +
Sbjct: 1740 NQMSITFLEPAYPTPGHVHRGQLQLVE-GNFRHTETRNTVSREELMMVLASLEQLQIRAL 1798
Query: 730 FSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQG 789
FS +A R+ E SP+ QG
Sbjct: 1799 FSQISSAVFLRRVALE------------VASPAG------------------------QG 1822
Query: 790 SLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY----GFGPTGCQACQCSHEGALSSLCEK 845
+L+S CLC G C CAPG+Y G C CQC S C
Sbjct: 1823 ALASNVE----LCLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGH---SDRCLP 1875
Query: 846 TSGQCL-CRTGAFGLRCDRCQRGQWGFPSCR-----PCV---------CNGHADECNTHT 890
SG C+ C+ G C+RCQ GF S R PCV N A+ C
Sbjct: 1876 GSGVCVDCQHNTEGAHCERCQA---GFVSSRDDPSAPCVSCPCPLSVPSNNFAEGCVLRG 1932
Query: 891 G--ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEY 948
G CL C+ G CERC GF G+P L G C+PC C G G + C D
Sbjct: 1933 GRTQCL-CKPGYAGASCERCAPGFFGNP-LVLGSSCQPCDC-SGNGDPNLLFSDC--DPL 1987
Query: 949 SQQIVCH-CRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQC 1007
+ C C TG RCE CAPG +G+ P G C C+C+ P +ACDPH+G C
Sbjct: 1988 TG--ACRGCLRHTTGPRCEICAPGFYGNALLP-GNCTRCDCT----PCGTEACDPHSGHC 2040
Query: 1008 LRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPC 1067
L C G C C+ G G C C C P+ + C P SGQC C
Sbjct: 2041 L-CKAGVTGRRCDRCQEGHFGFDGCGGCRPCACG---------PAAEGSECHPQSGQCHC 2090
Query: 1068 LPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE 1127
P GP C CAP +W L GC+ C C G C+ TG+C+C G G C
Sbjct: 2091 RPGTMGPQCRECAPGYWGLPE-QGCRRCQC-----PGGRCDPHTGRCNCPPGLSGERCDT 2144
Query: 1128 CQELHW----GDP---GLQCHACD-CDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG 1179
C + H G P + C CD C +D + R G + RG
Sbjct: 2145 CSQQHQVPVPGGPVGHSIHCEVCDHCVVLLLDDLE----------RAGALLPAIHEQLRG 2194
Query: 1180 F---SGIFPACHPCHACFGDWDRVVQ-------DLAARTQRLEQRAQEL----------- 1218
S + H +A D ++ + A + + LEQ++ L
Sbjct: 2195 INASSMAWARLHRLNASIADLQSQLRSPLGPRHETAQQLEVLEQQSTSLGQDARRLGGQA 2254
Query: 1219 -----QQTGVLGAFESSFWHMQEKLGIVQ-------------GIVGARNTSAASTAQLVE 1260
Q + +L E++ H + L ++ G +G N SA S QL+
Sbjct: 2255 VGTRDQASQLLAGTEATLGHAKTLLAAIRAVDRTLSELMSQTGHLGLANASAPSGEQLLR 2314
Query: 1261 ATEELRREIGEATEH-----LTQLEADLTDVQDENFNANHALSGLERDRLALNLTLR-QL 1314
E+ R + E EA+L Q LS L + AL R +L
Sbjct: 2315 TLAEVERLLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRL 2374
Query: 1315 DQH----LDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEA 1370
QH +DL + N A D+ R A ++ + R + ++A+ + A
Sbjct: 2375 AQHEAGLMDLREALN--RAVDATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHA 2432
Query: 1371 LMDAQKEDFNSKHMANQ--RALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGC 1428
D F H +Q L +L+A + + +P + A
Sbjct: 2433 ARDTLASVFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHA 2492
Query: 1429 RDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASEAQ 1488
+ + G L+ N ++ D+ Q L + E + SR+ + + A +A
Sbjct: 2493 Q------QLGQLALNLSSIILDV-------NQDRLTQRAIEASNAYSRILQAVQAAEDAA 2539
Query: 1489 QRAQAALDKANAS---RGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSI 1545
+A D A+ +G V++A Q L + L ++ + L L
Sbjct: 2540 GQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAMLQEQ------------QRLGLVW 2587
Query: 1546 PASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAE 1605
A L A++ + A + A A D + + A+ + A+D + +
Sbjct: 2588 AALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAAEAQDTATRVQ 2647
Query: 1606 T-VQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLD 1664
+ +QA E +R QG +G +RG +D Q + ++ E+ L +
Sbjct: 2648 SQLQAMQENVERWQGQYEG-LRG-----QDLGQAVLDAGHSVSTLEKTLPQLLAKL---- 2697
Query: 1665 ALLEALKLKRAGNSLAAS--TAEETAGSAQGRAQEAEQLLR--GPLGDQYQTVKALAERK 1720
++LE + A +L+AS E A+G A + + ++ G G Q +T + LA+
Sbjct: 2698 SILENRGVHNASLALSASIGRVRELIAQARGAASKVKVPMKFNGRSGVQLRTPRDLADLA 2757
Query: 1721 AQGVL 1725
A L
Sbjct: 2758 AYTAL 2762
Score = 300 bits (768), Expect = 8e-81
Identities = 281/960 (29%), Positives = 398/960 (41%), Gaps = 128/960 (13%)
Query: 836 EGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWG------FPSCRPCVCNGHADECNTH 889
+GAL+S E CLC G C C G + C PC C+GH+D C
Sbjct: 1821 QGALASNVEL----CLCPASYRGDSCQECAPGFYRDVKGLFLGRCVPCQCHGHSDRCLPG 1876
Query: 890 TGACLGCRDHTGGEHCERCIAGF---HGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQD 946
+G C+ C+ +T G HCERC AGF DP P C CPCP S +FA C
Sbjct: 1877 SGVCVDCQHNTEGAHCERCQAGFVSSRDDPSAP----CVSCPCPLSVPSN-NFAEGCVLR 1931
Query: 947 EYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDP-MDPDACDPHTG 1005
Q C C+ GY G CE CAPG FG+P G CQ C+CSGN DP + CDP TG
Sbjct: 1932 GGRTQ--CLCKPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNLLFSDCDPLTG 1989
Query: 1006 QCLRCLHHTEGPHCAHCKPGFHGQAARQ-SCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQ 1064
C CL HT GP C C PGF+G A +C RC C GT CDP SG
Sbjct: 1990 ACRGCLRHTTGPRCEICAPGFYGNALLPGNCTRCDCTPCGTEA----------CDPHSGH 2039
Query: 1065 CPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRT 1124
C C V G CDRC + GC+PCAC P+ A G C+ +GQCHCR G G
Sbjct: 2040 CLCKAGVTGRRCDRCQEGHFGFDGCGGCRPCACGPA-AEGSECHPQSGQCHCRPGTMGPQ 2098
Query: 1125 CSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIF 1184
C EC +WG P C C C +C TG C+C PG+SG RCD C++
Sbjct: 2099 CRECAPGYWGLPEQGCRRCQCPG-----GRCDPHTGRCNCPPGLSGERCDTCSQQHQVPV 2153
Query: 1185 PA--------CHPCHAC----FGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFW 1232
P C C C D +R L A ++L L +S
Sbjct: 2154 PGGPVGHSIHCEVCDHCVVLLLDDLERAGALLPAIHEQLRGINASSMAWARLHRLNASIA 2213
Query: 1233 HMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFN 1292
+Q +L + +G R+ TAQ +E E+ +G+ L D +
Sbjct: 2214 DLQSQL---RSPLGPRH----ETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLA 2266
Query: 1293 ANHALSGLERDRLALNLTLRQLDQHL-DLLKHSNFLGAYDSIRHAHSQSAEAERRANTSA 1351
A G + LA +R +D+ L +L+ + LG + +A + S E R
Sbjct: 2267 GTEATLGHAKTLLA---AIRAVDRTLSELMSQTGHLG----LANASAPSGEQLLR----T 2315
Query: 1352 LAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCG 1411
LA + AR + A + ++ A QR L ++ SL + N+ +
Sbjct: 2316 LAEVERLLWEMRARD-----LGAPQAAAEAELAAAQRLLARVQEQLS--SLWEENQAL-- 2366
Query: 1412 APGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGG 1471
RD Q G + A A A A+ + Q L E
Sbjct: 2367 -------------ATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRNQERLEEA- 2412
Query: 1472 SILSRVAETRRQASEAQQRAQAALDK-ANASR--GQVEQANQELQELIQSVKDFLNQEGA 1528
L R E R + Q AA D A+ R ++QA +EL+ L S+ +GA
Sbjct: 2413 --LQRKQELSRDNATLQATLHAARDTLASVFRLLHSLDQAKEELERLAASL------DGA 2464
Query: 1529 DPDSIEMVAT--------RVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDV 1580
++ + T R++E + A A+Q+ LA ++ + + + D + R +
Sbjct: 2465 RTPLLQRMQTFSPAGSKLRLVE-AAEAHAQQLGQLALNLSSIILDV-NQDRLTQRAIEAS 2522
Query: 1581 RRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLY 1640
++LQ + A A Q+A+ A + QG+ A + +A++ E+ +
Sbjct: 2523 NAYSRILQAVQAAEDAAGQALQQADHTWATVVR----QGLVDRA-QQLLANSTALEEAML 2577
Query: 1641 QVQERMAGAERALSSAGERARQLDALLEALK--LKRAGNSLAASTAEETAGSAQGRAQEA 1698
Q Q+R+ AL A + R + A + L+ ++ A LA T E + A +A A
Sbjct: 2578 QEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQAAQAMLAMDTDETSKKIAHAKAVAA 2637
Query: 1699 EQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGT 1758
E D V++ + + V Q + E LR +DL QA D + LE T
Sbjct: 2638 E------AQDTATRVQSQLQAMQENVERWQGQYEGLR--GQDLGQAVLDAGHSVSTLEKT 2689
Score = 271 bits (692), Expect = 5e-72
Identities = 185/595 (31%), Positives = 267/595 (44%), Gaps = 94/595 (15%)
Query: 23 LLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCG-----LNGPQP-- 75
LL V A L A A + G S +P +L G R+ AS+TCG P+P
Sbjct: 22 LLLVGLALLGAARAREEAG-GGFSLHPPYFNLAEGA--RIAASATCGEEAPARGSPRPTE 78
Query: 76 --YCIV----------SHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAW 123
YC + + + C +C +A ++ +H N + W
Sbjct: 79 DLYCKLVGGPVAGGDPNQTIRGQYCDIC------TAANSNKAHPASNAIDG-----TERW 127
Query: 124 WQS---ENGIP--AVTIQLDLEAEFHFTHLIMTFKTF-RPAAMLVERSADFGRTWHVYRY 177
WQS G+ V + LDL FH ++++ F RP ++ERS DFGRT+ +++
Sbjct: 128 WQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLERSMDFGRTYQPWQF 187
Query: 178 FSY---DCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPD-PYS 233
F+ DC F L D +C + YS I P GE++ +++ + YS
Sbjct: 188 FASSKRDCLERFGPQTLERITRDDAAICTTEYSRIVPLENGEIVVSLVNGRPGAMNFSYS 247
Query: 234 SRIQNLLKITNLRVNLTRLHTL-----GDNLLDPRREIREKYYYALYELVVRGNCFCYGH 288
++ K TN+R+ R +TL G L DP + +YYY++ ++ + G C C+GH
Sbjct: 248 PLLREFTKATNVRLRFLRTNTLLGHLMGKALRDPT--VTRRYYYSIKDISIGGRCVCHGH 305
Query: 289 ASEC-APAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKC 347
A C A P P + C C+HNT G C++C + PW+PA ++ C+ C
Sbjct: 306 ADACDAKDPTDPFRLQ------CTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSC 359
Query: 348 ECHGHTHSCHFDMAVYLASGNVS-------GGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
C+GH C++D V + S GGVC CQH+T G +CE C P FYR P
Sbjct: 360 NCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHP 419
Query: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL- 459
L P VCR C+C+ G C+ ++G+C C+ + G RC C +GF G
Sbjct: 420 LDSPHVCRRCNCE--SDFTDGTCED--------LTGRCYCRPNFSGERCDVCAEGFTGFP 469
Query: 460 ----SISDRLGCR----------RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRC 505
+ S R C C+A GT + DP G C CK G C+ C
Sbjct: 470 SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELC 529
Query: 506 LPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
PG +G GC+PC C G D +CD TGQC CR G C++ PGYF
Sbjct: 530 APGFYG-----PGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYF 579
Score = 259 bits (661), Expect = 2e-68
Identities = 150/410 (36%), Positives = 190/410 (46%), Gaps = 53/410 (12%)
Query: 783 CQCNPQGSLSSEC--NPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALS 840
C C+ G+ + C +P G+CLCKP G C+LCAPG+YG GCQ CQCS G
Sbjct: 494 CDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFYG---PGCQPCQCSSPGVAD 550
Query: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGCRD 898
C+ +GQC CR G G CDRC G + FP C+ C C+ G E G CL C+
Sbjct: 551 DRCDPDTGQCRCRVGFEGATCDRCAPGYFHFPLCQLCGCSPAGTLPEGCDEAGRCL-CQP 609
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCHCR 957
G HC+RC G+HG P C+ C C P G Q A +C CR
Sbjct: 610 EFAGPHCDRCRPGYHGFP------NCQACTCDPRGALDQLCGAGG----------LCRCR 653
Query: 958 AGYTGLRCEACAPGHFGDPSRPGGRCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTE 1015
GYTG C+ C+PG G PS C C CS G++ ACDP +GQC C
Sbjct: 654 PGYTGTACQECSPGFHGFPS-----CVPCHCSAEGSLHA----ACDPRSGQC-SCRPRVT 703
Query: 1016 GPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
G C C PG + C +C+ G P P+ + C C +V+GPS
Sbjct: 704 GLRCDTCVPGAYN---FPYCEAGSCHPAGLAPVDPALPE------AQVPCMCRAHVEGPS 754
Query: 1076 CDRCAPNFWNLTSGH--GCQPCACHPSRARG--PTCNEFTGQCHCRAGFGGRTCSECQEL 1131
CDRC P FW L+ + GC C+C G C TGQC C+ G+ C+ C++
Sbjct: 755 CDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQACASCKDG 814
Query: 1132 HWG---DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCAR 1178
+G C +C CD G C TG C CRP G C + AR
Sbjct: 815 FFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPAR 864
Score = 238 bits (608), Expect = 3e-62
Identities = 138/361 (38%), Positives = 173/361 (47%), Gaps = 36/361 (9%)
Query: 779 GALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGA 838
G PCQC+ G C+P GQC C+ G G CD CAPGY+ F CQ C CS G
Sbjct: 537 GCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF--PLCQLCGCSPAGT 594
Query: 839 LSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGC 896
L C++ +G+CLC+ G CDRC+ G GFP+C+ C C+ G D+ G C C
Sbjct: 595 LPEGCDE-AGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGAGGLC-RC 652
Query: 897 RDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHC 956
R G C+ C GFHG P C PC C ++ +C D S Q C C
Sbjct: 653 RPGYTGTACQECSPGFHGFP------SCVPCHC----SAEGSLHAAC--DPRSGQ--CSC 698
Query: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
R TGLRC+ C PG + P G C + +DP P+A P C+ C H EG
Sbjct: 699 RPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGLA-PVDPALPEAQVP----CM-CRAHVEG 752
Query: 1017 PHCAHCKPGFHGQAAR--QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
P C CKPGF G + + C RC+C+L GT C P +GQC C P+V G
Sbjct: 753 PSCDRCKPGFWGLSPSNPEGCTRCSCDLRGT------LGGVAECQPGTGQCFCKPHVCGQ 806
Query: 1075 SCDRCAPNFWNLTSG--HGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELH 1132
+C C F+ L GC+ C C A G +C TG C CR G TCSE H
Sbjct: 807 ACASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDH 866
Query: 1133 W 1133
+
Sbjct: 867 Y 867
Score = 206 bits (524), Expect = 2e-52
Identities = 148/448 (33%), Positives = 182/448 (40%), Gaps = 89/448 (19%)
Query: 796 NPHGGQCLCKPGVVGRRCDLCAPGYY--------GFGPTGCQACQC-------------S 834
+P QC C+ G CD C PG+ CQ+C C
Sbjct: 316 DPFRLQCTCQHNTCGGTCDRCCPGFNQQPWKPATANSANECQSCNCYGHATDCYYDPEVD 375
Query: 835 HEGALSSL--CEKTSGQCL-CRTGAFGLRCDRCQRGQWGFPS--------CRPCVCNGHA 883
A SL + G C+ C+ G+ C+RC G + P+ CR C C
Sbjct: 376 RRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNHPLDSPHVCRRCNCESDF 435
Query: 884 DE--CNTHTGACLGCRDHTGGEHCERCIAGFHGDPR---------------LPYGGQCRP 926
+ C TG C CR + GE C+ C GF G P LP GQ
Sbjct: 436 TDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTGFPSCYPTPSSSNDTREQVLP-AGQIVN 493
Query: 927 CPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLC 986
C C G+Q +C +D + C C+ + G CE CAPG +G PG CQ C
Sbjct: 494 CDC-SAAGTQ---GNACRKDPRVGR--CLCKPNFQGTHCELCAPGFYG----PG--CQPC 541
Query: 987 ECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG-FHGQAARQSCHRCTCNLLGT 1045
+CS + D CDP TGQC RC EG C C PG FH C C C+ GT
Sbjct: 542 QCSS--PGVADDRCDPDTGQC-RCRVGFEGATCDRCAPGYFHFPL----CQLCGCSPAGT 594
Query: 1046 NPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGP 1105
P+ C +G+C C P GP CDRC P + + CQ C C P A
Sbjct: 595 LPEGCDE---------AGRCLCQPEFAGPHCDRCRPGYHGFPN---CQACTCDPRGALDQ 642
Query: 1106 TCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCR 1165
C G C CR G+ G C EC G P C C C + G C +G CSCR
Sbjct: 643 LCGA-GGLCRCRPGYTGTACQECSPGFHGFPS--CVPCHCSAEGSLHAACDPRSGQCSCR 699
Query: 1166 PGVSGVRCDQCARGFSGIFPACH--PCH 1191
P V+G+RCD C G FP C CH
Sbjct: 700 PRVTGLRCDTCVPGAYN-FPYCEAGSCH 726
Score = 175 bits (444), Expect = 3e-43
Identities = 121/399 (30%), Positives = 152/399 (38%), Gaps = 104/399 (26%)
Query: 877 CVCNGHADECNTHTGA------CLGCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRP 926
CVC+GHAD C+ C C+ +T G C+RC GF+ P P +C+
Sbjct: 300 CVCHGHADACDAKDPTDPFRLQCT-CQHNTCGGTCDRCCPGFNQQPWKPATANSANECQS 358
Query: 927 C-------PCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHFGDPSR 978
C C P R A+ Y VC C+ TG+ CE C PG + P+
Sbjct: 359 CNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRSPNH 418
Query: 979 PGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSC 1035
P C+ C C + C+ TG+C C + G C C GF G SC
Sbjct: 419 PLDSPHVCRRCNCESD---FTDGTCEDLTGRCY-CRPNFSGERCDVCAEGFTG---FPSC 471
Query: 1036 H--------------------RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
+ C C+ GT + C DP G+C C PN QG
Sbjct: 472 YPTPSSSNDTREQVLPAGQIVNCDCSAAGT------QGNACRKDPRVGRCLCKPNFQGTH 525
Query: 1076 CDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGD 1135
C+ CAP F+ G GCQPC C C+ TGQC CR GF G TC C ++
Sbjct: 526 CELCAPGFY----GPGCQPCQCSSPGVADDRCDPDTGQCRCRVGFEGATCDRCAPGYFHF 581
Query: 1136 PGLQ-------------------------------------------CHACDCDSRGIDT 1152
P Q C AC CD RG
Sbjct: 582 PLCQLCGCSPAGTLPEGCDEAGRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALD 641
Query: 1153 PQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCH 1191
C G C CRPG +G C +C+ GF G FP+C PCH
Sbjct: 642 QLCGA-GGLCRCRPGYTGTACQECSPGFHG-FPSCVPCH 678
Score = 164 bits (415), Expect = 7e-40
Identities = 102/280 (36%), Positives = 131/280 (46%), Gaps = 38/280 (13%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
C C+GH+ C P G C+ C+HNT G +CE+CQ + + D S
Sbjct: 1864 CQCHGHSDRCLPGSGV-----------CVDCQHNTEGAHCERCQAGFVS-----SRDDPS 1907
Query: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDL 401
C C C S +F L G C C+ AG CE C P F+ +P L
Sbjct: 1908 APCVSCPCPLSVPSNNFAEGCVLRGGRTQ---CL-CKPGYAGASCERCAPGFFGNP---L 1960
Query: 402 RDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLS 460
+ C+ CDC G+ D S DP ++G CR C H G RC+ C GF+G +
Sbjct: 1961 VLGSSCQPCDCS--GNGDPNLLFSDCDP----LTGACRGCLRHTTGPRCEICAPGFYGNA 2014
Query: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
+ C RC C GT CDP+SG C CK VTGR CDRC GH+G GCR
Sbjct: 2015 LLPG-NCTRCDCTPCGT----EACDPHSGHCLCKAGVTGRRCDRCQEGHFGFD-GCGGCR 2068
Query: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
PC C A +C +GQCHCR +G +C + PGY+
Sbjct: 2069 PCACG-PAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYW 2107
Score = 162 bits (411), Expect = 2e-39
Identities = 105/341 (30%), Positives = 145/341 (42%), Gaps = 50/341 (14%)
Query: 292 CAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLP------------------- 332
C+PA P + G C+C+ G +C++C+ Y P
Sbjct: 589 CSPAGTLPEGCDEA--GRCLCQPEFAGPHCDRCRPGYHGFPNCQACTCDPRGALDQLCGA 646
Query: 333 -----WRPAEDGHSHACRKCE--CHGHTHS--CHFDMAVYL-ASGNVSGGVCDGCQHNTA 382
RP G AC++C HG CH L A+ + G C C+
Sbjct: 647 GGLCRCRPGYTGT--ACQECSPGFHGFPSCVPCHCSAEGSLHAACDPRSGQCS-CRPRVT 703
Query: 383 GRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKE 442
G C+ C P Y P C + C P G + DPAL C C+
Sbjct: 704 GLRCDTCVPGAYNFP--------YCEAGSCHPAGL-------APVDPALPEAQVPCMCRA 748
Query: 443 HVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
HV G C +C+ GF+GLS S+ GC RC C+ RGT+ G C P +G C+CK V G+ C
Sbjct: 749 HVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAECQPGTGQCFCKPHVCGQAC 808
Query: 503 DRCLPGHWGLSH-DLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
C G +GL D GCR C CD+GGAL C+ TG C CR + G C + ++
Sbjct: 809 ASCKDGFFGLDQADYFGCRSCRCDIGGALGQSCEPRTGVCRCRPNTQGPTCSEPARDHYL 868
Query: 562 PFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSGFVRL 602
P L HL E E+ V P E +++ G+ ++
Sbjct: 869 PDLHHLRLELEEAATPEGHAVRFGFNPLEFENFSWRGYAQM 909
Score = 143 bits (360), Expect = 2e-33
Identities = 90/255 (35%), Positives = 116/255 (45%), Gaps = 39/255 (15%)
Query: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGV 808
C +G S +S S C SLS NGA PC C+ G+ C P GGQC C V
Sbjct: 1404 CAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCGCHEVGATGPTCEPFGGQCPCHAHV 1463
Query: 809 VGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQ 868
+GR C CA GY+GF C+ C C + LC++ +GQC+C C CQ
Sbjct: 1464 IGRDCSRCATGYWGF--PNCRPCDCG-----ARLCDELTGQCICPPRTIPPDCLLCQPQT 1516
Query: 869 WG---FPSCRPCVCNGHADE------CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLP 919
+G C C C+G + C+T +G C CR + G C+ C GFHG PR
Sbjct: 1517 FGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQC-KCRPNVTGRRCDTCSPGFHGYPR-- 1573
Query: 920 YGGQCRPCPCPE---GPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-D 975
CRPC C E PG C D + Q C+C+ G +C+ C+ G F D
Sbjct: 1574 ----CRPCDCHEAGTAPG-------VC--DPLTGQ--CYCKENVQGPKCDQCSLGTFSLD 1618
Query: 976 PSRPGGRCQLCECSG 990
+ P G C C C G
Sbjct: 1619 AANPKG-CTRCFCFG 1632
Score = 134 bits (338), Expect = 6e-31
Identities = 102/345 (29%), Positives = 133/345 (38%), Gaps = 101/345 (29%)
Query: 282 NCFCYGHASECAPAPG-----APAHAEGMVHGA--CI-CKHNTRGLNCEQC-QDFYRDLP 332
+C CYGHA++C P A +G G CI C+H+T G+NCE+C FYR P
Sbjct: 358 SCNCYGHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCERCLPGFYRS-P 416
Query: 333 WRPAEDGHSHACRK-----------CE-----------------------------CHGH 352
P + H CR+ CE C+
Sbjct: 417 NHPLDS--PHVCRRCNCESDFTDGTCEDLTGRCYCRPNFSGERCDVCAEGFTGFPSCYPT 474
Query: 353 THSCHFDMAVYLASGNVSGGVCDG------------------CQHNTAGRHCELCRPFFY 394
S + L +G + C C+ N G HCELC P FY
Sbjct: 475 PSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKPNFQGTHCELCAPGFY 534
Query: 395 RDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRD 454
C+ C C G D RCD +GQCRC+ G C +C
Sbjct: 535 GPG---------CQPCQCSSPGVADD-RCDPD--------TGQCRCRVGFEGATCDRCAP 576
Query: 455 GFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSH 514
G+F + C+ C C+ GT+P CD +G C C+ G CDRC PG+ H
Sbjct: 577 GYFHFPL-----CQLCGCSPAGTLPEG--CD-EAGRCLCQPEFAGPHCDRCRPGY----H 624
Query: 515 DLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
C+ C CD GALD C G G C CR G C++ PG+
Sbjct: 625 GFPNCQACTCDPRGALDQLCGAG-GLCRCRPGYTGTACQECSPGF 668
Score = 123 bits (309), Expect = 1e-27
Identities = 71/207 (34%), Positives = 90/207 (43%), Gaps = 20/207 (9%)
Query: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHE 836
+ +PC C+ +GSL + C+P GQC C+P V G RCD C PG Y F +C +
Sbjct: 671 FPSCVPCHCSAEGSLHAACDPRSGQCSCRPRVTGLRCDTCVPGAYNFPYCEAGSCHPAGL 730
Query: 837 GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-PS----CRPCVCN-----GHADEC 886
+ + C+CR G CDRC+ G WG PS C C C+ G EC
Sbjct: 731 APVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDLRGTLGGVAEC 790
Query: 887 NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQD 946
TG C C+ H G+ C C GF G + Y G CR C C G SC
Sbjct: 791 QPGTGQCF-CKPHVCGQACASCKDGFFGLDQADYFG-CRSCRCDIGGA----LGQSCE-- 842
Query: 947 EYSQQIVCHCRAGYTGLRCEACAPGHF 973
+ VC CR G C A H+
Sbjct: 843 --PRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 115 bits (289), Expect = 3e-25
Identities = 86/290 (29%), Positives = 109/290 (37%), Gaps = 45/290 (15%)
Query: 949 SQQIVCHCRA-GY------TGLRCEACAPG---HFGDPSRPGGRCQLCECSGNIDPMDPD 998
S + HC A GY + L C A + + +RP G C G P
Sbjct: 1397 SYDFISHCAAQGYHISPSSSSLFCRNAAASLSLFYNNGARPCG----CHEVGATGP---- 1448
Query: 999 ACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHC 1058
C+P GQC C H G C+ C G+ G +C C C C
Sbjct: 1449 TCEPFGGQC-PCHAHVIGRDCSRCATGYWGFP---NCRPCDCGAR-------------LC 1491
Query: 1059 DPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHP---SRARGPTCNEFTGQCH 1115
D +GQC C P P C C P + GC+ C C PTC+ +GQC
Sbjct: 1492 DELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQELTDPTCDTDSGQCK 1551
Query: 1116 CRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
CR GR C C G P +C CDC G C TG C C+ V G +CDQ
Sbjct: 1552 CRPNVTGRRCDTCSPGFHGYP--RCRPCDCHEAGTAPGVCDPLTGQCYCKENVQGPKCDQ 1609
Query: 1176 CARGFSGIFPA----CHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQT 1221
C+ G + A C C CFG +R R + ++ L T
Sbjct: 1610 CSLGTFSLDAANPKGCTRCF-CFGATERCRSSSYTRQEFVDMEGWVLLST 1658
Score = 95.1 bits (235), Expect = 5e-19
Identities = 69/257 (26%), Positives = 94/257 (36%), Gaps = 59/257 (22%)
Query: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
+C CHGH +C + CQHNT G C+ C P F + P K +
Sbjct: 299 RCVCHGHADACDAKDPTDPFRLQCT------CQHNTCGGTCDRCCPGFNQQPWKPATANS 352
Query: 406 V--CRSCDCDPMGSQDGGRCDSHDDPALGLV------------SGQC-RCKEHVVGTRCQ 450
C+SC+C G D + DP + G C C+ H G C+
Sbjct: 353 ANECQSCNCY------GHATDCYYDPEVDRRRASQSLDGTYQGGGVCIDCQHHTTGVNCE 406
Query: 451 QCRDGFF---GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLP 507
+C GF+ + CRRC C + T C+ +G CYC+ +G CD C
Sbjct: 407 RCLPGFYRSPNHPLDSPHVCRRCNCESDFT---DGTCEDLTGRCYCRPNFSGERCDVCAE 463
Query: 508 GHWGLSHDLLGCRP--------------------CDCDVGGALDPQC--DEGTGQCHCRQ 545
G G C P CDC G C D G+C C+
Sbjct: 464 GFTGFP----SCYPTPSSSNDTREQVLPAGQIVNCDCSAAGTQGNACRKDPRVGRCLCKP 519
Query: 546 HMVGRRCEQVQPGYFRP 562
+ G CE PG++ P
Sbjct: 520 NFQGTHCELCAPGFYGP 536
Score = 82.4 bits (202), Expect = 4e-15
Identities = 48/147 (32%), Positives = 61/147 (41%), Gaps = 22/147 (14%)
Query: 745 ERYQCHEEGLVPSKTSPSEA-----------------CAPLLISLSTLIYNGALPCQCNP 787
E CH GL P + EA C P LS G C C+
Sbjct: 721 EAGSCHPAGLAPVDPALPEAQVPCMCRAHVEGPSCDRCKPGFWGLSPSNPEGCTRCSCDL 780
Query: 788 QGSLS--SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPT---GCQACQCSHEGALSSL 842
+G+L +EC P GQC CKP V G+ C C G++G GC++C+C GAL
Sbjct: 781 RGTLGGVAECQPGTGQCFCKPHVCGQACASCKDGFFGLDQADYFGCRSCRCDIGGALGQS 840
Query: 843 CEKTSGQCLCRTGAFGLRCDRCQRGQW 869
CE +G C CR G C R +
Sbjct: 841 CEPRTGVCRCRPNTQGPTCSEPARDHY 867
Score = 80.1 bits (196), Expect = 2e-14
Identities = 47/151 (31%), Positives = 59/151 (39%), Gaps = 45/151 (29%)
Query: 452 CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWG 511
CR+ LS+ G R C C+ G G T C+P G C C V GR C RC G+WG
Sbjct: 1420 CRNAAASLSLFYNNGARPCGCHEVGAT-GPT-CEPFGGQCPCHAHVIGRDCSRCATGYWG 1477
Query: 512 L----------------------------------------SHDLLGCRPCDCDVGG--- 528
H L+GC C+C G
Sbjct: 1478 FPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQPQTFGCHPLVGCEECNCSGPGIQE 1537
Query: 529 ALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
DP CD +GQC CR ++ GRRC+ PG+
Sbjct: 1538 LTDPTCDTDSGQCKCRPNVTGRRCDTCSPGF 1568
Score = 78.6 bits (192), Expect = 5e-14
Identities = 63/206 (30%), Positives = 78/206 (37%), Gaps = 44/206 (21%)
Query: 281 GNCFCYGHA-----SECAPAP-GAP--------AHAEGMVHGACICKHNTRGLNCEQCQD 326
G C C+ H S CA G P A + G CIC T +C CQ
Sbjct: 1455 GQCPCHAHVIGRDCSRCATGYWGFPNCRPCDCGARLCDELTGQCICPPRTIPPDCLLCQP 1514
Query: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHC 386
+ P C +C C G D SG C+ N GR C
Sbjct: 1515 --QTFGCHPLV-----GCEECNCSGPGIQELTDPTCDTDSGQCK------CRPNVTGRRC 1561
Query: 387 ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVG 446
+ C P F+ P CR CDC G+ G CD ++GQC CKE+V G
Sbjct: 1562 DTCSPGFHGYPR--------CRPCDCHEAGTAPGV-CDP--------LTGQCYCKENVQG 1604
Query: 447 TRCQQCRDGFFGLSISDRLGCRRCQC 472
+C QC G F L ++ GC RC C
Sbjct: 1605 PKCDQCSLGTFSLDAANPKGCTRCFC 1630
Score = 45.4 bits (106), Expect = 5e-04
Identities = 34/118 (28%), Positives = 41/118 (34%), Gaps = 30/118 (25%)
Query: 287 GHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRK 346
G CA P A G C C+ T G C +C Y LP CR+
Sbjct: 2065 GGCRPCACGPAAEGSECHPQSGQCHCRPGTMGPQCRECAPGYWGLP--------EQGCRR 2116
Query: 347 CECHG-----HTHSCHFDMAVYLASGNVSGGVCDGC--QHNTA--------GRHCELC 389
C+C G HT C+ +SG CD C QH HCE+C
Sbjct: 2117 CQCPGGRCDPHTGRCN-------CPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVC 2167
Score = 45.4 bits (106), Expect = 5e-04
Identities = 94/396 (23%), Positives = 153/396 (38%), Gaps = 78/396 (19%)
Query: 1457 RHTQAELQRALAEGGSILSRVAE--------TRRQASEAQQRAQAALDKANASRGQVEQA 1508
RH A+ L + + L + A TR QAS+ +A L A +
Sbjct: 2226 RHETAQQLEVLEQQSTSLGQDARRLGGQAVGTRDQASQLLAGTEATLGHAKTLLAAIRAV 2285
Query: 1509 NQELQELIQSVKDFLNQEGADPDSIEMVAT-----------RVLELSIPASAEQI----- 1552
++ L EL+ + P +++ T R +L P +A +
Sbjct: 2286 DRTLSELMSQTGHLGLANASAPSGEQLLRTLAEVERLLWEMRARDLGAPQAAAEAELAAA 2345
Query: 1553 QHLAGAIAERVRSLADVDAILARTVGD-VRRAEQLLQDARRARSWAEDEKQKAETV---- 1607
Q L + E++ SL + + LA D + + E L D R A + A D ++A+ +
Sbjct: 2346 QRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGLMDLREALNRAVDATREAQELNSRN 2405
Query: 1608 QAALEEA-QRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDAL 1666
Q LEEA QR Q +++ D + TL+ ++ +A R L S + +L+ L
Sbjct: 2406 QERLEEALQRKQELSR--------DNATLQATLHAARDTLASVFRLLHSLDQAKEELERL 2457
Query: 1667 LEALK------LKRAGNSLAASTAEETAGSAQGRAQEAEQL---LRGPLGDQYQ---TVK 1714
+L L+R A + +A+ AQ+ QL L + D Q T +
Sbjct: 2458 AASLDGARTPLLQRMQTFSPAGSKLRLVEAAEAHAQQLGQLALNLSSIILDVNQDRLTQR 2517
Query: 1715 ALAERKA-----QGVLAAQARAEQLRDEA---------RDLLQAAQDKLQRLQELE-GTY 1759
A+ A Q V AA+ A Q +A + L+ AQ L LE
Sbjct: 2518 AIEASNAYSRILQAVQAAEDAAGQALQQADHTWATVVRQGLVDRAQQLLANSTALEEAML 2577
Query: 1760 EENER------ALESKAAQL-------DGLEARMRS 1782
+E +R AL+ QL D LEA +++
Sbjct: 2578 QEQQRLGLVWAALQGARTQLRDVRAKKDQLEAHIQA 2613
Score = 39.3 bits (90), Expect = 0.035
Identities = 90/397 (22%), Positives = 149/397 (37%), Gaps = 60/397 (15%)
Query: 1418 CATSPCGGAGCRDEDGQPRC----GGLSCNGAAATADLAL-----GRARHTQA------- 1461
C C G C G+ C G C+ + + + G + H +
Sbjct: 2114 CRRCQCPGGRCDPHTGRCNCPPGLSGERCDTCSQQHQVPVPGGPVGHSIHCEVCDHCVVL 2173
Query: 1462 ---ELQRALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQS 1518
+L+RA G++L + E R + A A A L + NAS + +L
Sbjct: 2174 LLDDLERA----GALLPAIHEQLRGIN-ASSMAWARLHRLNAS----------IADLQSQ 2218
Query: 1519 VKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVG 1578
++ L +E VLE + + + L G + V + +LA T
Sbjct: 2219 LRSPLGPRHETAQQLE-----VLEQQSTSLGQDARRLGG---QAVGTRDQASQLLAGTEA 2270
Query: 1579 DVRRAEQLLQDARRA-RSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQ 1637
+ A+ LL R R+ +E ++T L A G + + E+
Sbjct: 2271 TLGHAKTLLAAIRAVDRTLSE---LMSQTGHLGLANASAPSG------EQLLRTLAEVER 2321
Query: 1638 TLYQVQERMAGAERALSSAGERARQ--LDALLEALK-LKRAGNSLAASTAEETAGSAQGR 1694
L++++ R GA +A + A A Q L + E L L +LA T + A G
Sbjct: 2322 LLWEMRARDLGAPQAAAEAELAAAQRLLARVQEQLSSLWEENQALATQTRDRLAQHEAGL 2381
Query: 1695 AQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQL-RDEA--RDLLQAAQDKLQR 1751
E L R D + + L R + + A R ++L RD A + L AA+D L
Sbjct: 2382 MDLREALNRAV--DATREAQELNSRNQERLEEALQRKQELSRDNATLQATLHAARDTLAS 2439
Query: 1752 LQELEGTYEENERALESKAAQLDGLEARMRSVLQAIN 1788
+ L + ++ + LE AA LDG + +Q +
Sbjct: 2440 VFRLLHSLDQAKEELERLAASLDGARTPLLQRMQTFS 2476
>gi|110611156 laminin, gamma 3 precursor [Homo sapiens]
Length = 1575
Score = 305 bits (781), Expect = 3e-82
Identities = 279/981 (28%), Positives = 421/981 (42%), Gaps = 129/981 (13%)
Query: 850 CLCRTGAFGLRCDRCQRG------QWG-FPSCRPCVCNGHADECNTHTGACLGCRDHTGG 902
C C TG G C+ C G Q G + SC PC CN H C+ +TG C+ C HT G
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT-CDPNTGICV-CSHHTEG 730
Query: 903 EHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC-HCRAGYT 961
CERC+ GF+G+P C+PCPCP ++C S+++VC HC G
Sbjct: 731 PSCERCLPGFYGNPFAGQADDCQPCPCPG--------QSACTTIPESREVVCTHCPPGQR 782
Query: 962 GLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPH 1018
G RCE C G FGDP G C C+CSGN+DP CDP +G CLRCLH+T G H
Sbjct: 783 GRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDH 842
Query: 1019 CAHCKPGFHGQAAR----QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGP 1074
C HC+ GF+G A C C+C+ G+ +Q P CDP +GQC CLP+V
Sbjct: 843 CEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMP------CDPVTGQCSCLPHVTAR 896
Query: 1075 SCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWG 1134
C RC P F++L G GC+ C CHP ++ C+ TGQC CR G G+ C CQ +G
Sbjct: 897 DCSRCYPGFFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFG 956
Query: 1135 DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPCHACF 1194
C AC C G + QCH G C CRPG G +CD+C F H C C
Sbjct: 957 FSIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTADGTH-CQQCP 1014
Query: 1195 GDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKL-------GIVQG---I 1244
+ V ++ A RL L + + G+ S W + L + QG +
Sbjct: 1015 SCYALVKEEAAKLKARL-----TLTEGWLQGSDCGSPWGPLDILLGEAPRGDVYQGHHLL 1069
Query: 1245 VGARNTSAASTAQLVEATEELRREIGEATE--------------HLTQLEADLTDVQDEN 1290
GAR L A + R ++ + L LEA L ++E
Sbjct: 1070 PGAREAFLEQMMSLEGAVKAAREQLQRLNKGARCAQAGSQKTCTQLADLEAVLESSEEEI 1129
Query: 1291 FNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTS 1350
+A L+ LE + + Q + L + L S R ++ A RA +
Sbjct: 1130 LHAAAILASLEIPQEGPS----QPTKWSHLATEARALAR--SHRDTATKIAATAWRALLA 1183
Query: 1351 ALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVC 1410
+ + + N R E D ED + A Q+AL T + E++
Sbjct: 1184 SNTSYALLWNLLEGRVALETQRDL--EDRYQEVQAAQKAL-----------RTAVAEVLP 1230
Query: 1411 GAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEG 1470
A ++ AT GA D P L+ GA A +A L++ +A
Sbjct: 1231 EA--ESVLATVQQVGA-----DTAPYLALLASPGALPQKSRAEDLGLKAKA-LEKTVASW 1282
Query: 1471 GSILSRVAETRRQASEAQQRAQAALDKAN-ASRGQVEQANQELQELIQSVKDFLNQEGAD 1529
+ + A T + A++A R L K + +R + QA+ +Q +V GA
Sbjct: 1283 QHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVM------GAR 1336
Query: 1530 PDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQD 1589
++ + L+ P +Q A ++++R +LA T ++AE++L +
Sbjct: 1337 TLLADLEGMK-LQFPRPKDQAALQRKADSVSDR---------LLADTRKKTKQAERMLGN 1386
Query: 1590 ARRARSWAEDEKQKAETVQAALEEAQRAQGI---AQGAIRGAVADTRDTEQTLYQVQERM 1646
A S A+ + ++AE + A + A+ A+ + + A R A T T+ TL Q +++
Sbjct: 1387 AAPLSSSAKKKGREAEVL--AKDSAKLAKALLRERKQAHRRASRLTSQTQATLQQASQQV 1444
Query: 1647 AGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPL 1706
+E A E A ++ A L ++ + + ++ ET +E L R
Sbjct: 1445 LASE-ARRQELEEAERVGAGLSEMEQQIRESRISLEKDIETL---------SELLARLGS 1494
Query: 1707 GDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERAL 1766
D +Q AQ + Q E+LR + + Q KL L++ E +
Sbjct: 1495 LDTHQA-------PAQALNETQWALERLRLQLGS-PGSLQRKLSLLEQESQQQELQIQGF 1546
Query: 1767 ESKAAQLDGLEARMRSVLQAI 1787
ES A++ + + ++L ++
Sbjct: 1547 ESDLAEIRADKQNLEAILHSL 1567
Score = 259 bits (661), Expect = 2e-68
Identities = 171/515 (33%), Positives = 238/515 (46%), Gaps = 72/515 (13%)
Query: 36 APDVPGCSRGSCYPATG----------DLLVGRADRLTASSTCGLNGPQPYCI-VSHLQD 84
AP G G+CY G + GR + AS TCG + P+ +C V
Sbjct: 14 APRAAGAGMGACYDGAGRPQRCLPVFENAAFGRLAQ--ASHTCG-SPPEDFCPHVGAAGA 70
Query: 85 EKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSEN---GIP---AVTIQLD 138
C CD+ +P H + +T F Q + WWQS + G+ +V I L
Sbjct: 71 GAHCQRCDAA-------DPQRHHNASYLTDFHSQDESTWWQSPSMAFGVQYPTSVNITLR 123
Query: 139 LEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADF---PGVPLAPPR 195
L + T++ + F T RP + + + + W Y+++S C + G L P
Sbjct: 124 LGKAYEITYVRLKFHTSRPESFAIYKRSRADGPWEPYQFYSASCQKTYGRPEGQYLRPGE 183
Query: 196 HWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPY----SSRIQNLLKITNLRVNLTR 251
C S +S+I P + G V + L+ P Y S +Q + T L ++L R
Sbjct: 184 DERVAFCTSEFSDISPLSGGNVAFSTLEGR---PSAYNFEESPGLQEWVTSTELLISLDR 240
Query: 252 LHTLGDNLL-DPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGAC 310
L+T GD++ DP+ + + YYYA+ + V G C C GHASEC P AC
Sbjct: 241 LNTFGDDIFKDPK--VLQSYYYAVSDFSVGGRCKCNGHASECGPDVAGQL--------AC 290
Query: 311 ICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS 370
C+HNT G +CE+C F++D PW +H C C C G + C FD ++ ++G+
Sbjct: 291 RCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNCSGRSEECTFDRELFRSTGH-- 348
Query: 371 GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPA 430
GG C C+ +TAG HCE C+ FY D R P C+ CDC GS +CD
Sbjct: 349 GGRCHHCRDHTAGPHCERCQENFYH---WDPRMP--CQPCDCQSAGSLH-LQCDD----- 397
Query: 431 LGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS 490
+G C CK V G +C +C GF LS GCR C CN G++ CDP SG
Sbjct: 398 ----TGTCACKPTVTGWKCDRCLPGFHSLSEG---GCRPCTCNPAGSL---DTCDPRSGR 447
Query: 491 CYCKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
C CK V G CDRC PG + L H+ GC C C
Sbjct: 448 CPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFC 482
Score = 196 bits (497), Expect = 2e-49
Identities = 123/367 (33%), Positives = 149/367 (40%), Gaps = 51/367 (13%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPTG-----CQACQCSHEGALSSLCEKTSGQCLCRTGA 856
C C G G+ C+ CAPGY P G C C C+ G C+ +G C+C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT----CDPNTGICVCSHHT 728
Query: 857 FGLRCDRCQRGQWGFP------SCRPCVCNGHADECNT----HTGACLGCRDHTGGEHCE 906
G C+RC G +G P C+PC C G + C T C C G CE
Sbjct: 729 EGPSCERCLPGFYGNPFAGQADDCQPCPCPGQS-ACTTIPESREVVCTHCPPGQRGRRCE 787
Query: 907 RCIAGFHGDPRLPYG--GQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHCRAG 959
C GF GDP +G C C C P G+ + C C
Sbjct: 788 VCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHC----------LRCLHN 837
Query: 960 YTGLRCEACAPGHFGD--PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
TG CE C G +G RP +C C C + CDP TGQC CL H
Sbjct: 838 TTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQC-SCLPHVTAR 896
Query: 1018 HCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCD 1077
C+ C PGF + C C C+ LG+ DQCH P +GQC C P V G +CD
Sbjct: 897 DCSRCYPGFFDLQPGRGCRSCKCHPLGS------QEDQCH--PKTGQCTCRPGVTGQACD 948
Query: 1078 RCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQE-LHWGDP 1136
RC F+ S GC+ C C P A C+E G C CR GF G C C +
Sbjct: 949 RCQLGFFGF-SIKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFFLTAD 1006
Query: 1137 GLQCHAC 1143
G C C
Sbjct: 1007 GTHCQQC 1013
Score = 184 bits (466), Expect = 9e-46
Identities = 116/341 (34%), Positives = 153/341 (44%), Gaps = 50/341 (14%)
Query: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG----CQACQ 832
Y +PC CN G+ C+P+ G C+C G C+ C PG+YG G CQ C
Sbjct: 701 YASCVPCTCNQHGT----CDPNTGICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCP 756
Query: 833 CSHEGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP--------SCRPCVCNGHA 883
C + A +++ E C C G G RC+ C G +G P C C C+G+
Sbjct: 757 CPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNV 816
Query: 884 D-----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY-GGQCRPCPC-PEGPGSQ 936
D C+ +G CL C +T G+HCE C GF+G P +C PC C P+G S+
Sbjct: 817 DPNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSE 876
Query: 937 RHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPM- 995
+ C D + Q C C T C C PG F +PG C+ C+C P+
Sbjct: 877 Q---MPC--DPVTGQ--CSCLPHVTARDCSRCYPGFF--DLQPGRGCRSCKC----HPLG 923
Query: 996 -DPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPD 1054
D C P TGQC C G C C+ GF G + + C C C+ LG +
Sbjct: 924 SQEDQCHPKTGQC-TCRPGVTGQACDRCQLGFFGFSIK-GCRACRCSPLGA------ASA 975
Query: 1055 QCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPC 1095
QCH +G C C P +G CDRC NF+ G CQ C
Sbjct: 976 QCH---ENGTCVCRPGFEGYKCDRCHDNFFLTADGTHCQQC 1013
Score = 169 bits (429), Expect = 2e-41
Identities = 147/506 (29%), Positives = 189/506 (37%), Gaps = 118/506 (23%)
Query: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSS 841
PC C GSL +C+ G C CKP V G +CD C PG++ GC+ C C+ G+L +
Sbjct: 382 PCDCQSAGSLHLQCDDTG-TCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
Query: 842 LCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADEC---------- 886
C+ SG+C C+ G CDRC+ G + C C C GH+ C
Sbjct: 441 -CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGHSKVCASTAQFQVHH 499
Query: 887 ---NTHTGA-CLGCRDHTGGEHCERCIAG-----------------FHGDPRLPYGGQC- 924
+ H GA R G EH + F GD R YG
Sbjct: 500 ILSDFHQGAEGWWARSVGGSEHPPQWSPNGVLLSPEDEEELTAPEKFLGDQRFSYGQPLI 559
Query: 925 ---------RPCPC--------------------PEGPGSQRHFATSCHQDEYSQQIV-- 953
P P P+ G R H E S+ +
Sbjct: 560 LTFRVPPGDSPLPVQLRLEGTGLALSLRHSSLSGPQDAGHPREVELRFHLQETSEDVAPP 619
Query: 954 ------CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTG-Q 1006
A T LR +PG PS P G L E + P P + +
Sbjct: 620 LPPFHFQRLLANLTSLRLRV-SPG----PS-PAGPVFLTEV--RLTSARPGLSPPASWVE 671
Query: 1007 CLRCLHHTEGPHCAHCKPGFHGQAAR----QSCHRCTCNLLGTNPQQCPSPDQCHCDPSS 1062
C G C C PG+ + + SC CTCN GT CDP++
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------------CDPNT 719
Query: 1063 GQCPCLPNVQGPSCDRCAPNFW-NLTSGHG--CQPCACHPSRARGPTCNEFTGQ--CHCR 1117
G C C + +GPSC+RC P F+ N +G CQPC C P ++ T E HC
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPC-PGQSACTTIPESREVVCTHCP 778
Query: 1118 AGFGGRTCSECQELHWGDP-GL-----QCHACDCDSRGID---TPQCHRFTGHC-SCRPG 1167
G GR C C + +GDP GL CH C C S +D C +GHC C
Sbjct: 779 PGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQC-SGNVDPNAVGNCDPLSGHCLRCLHN 837
Query: 1168 VSGVRCDQCARGFSGIFPACHPCHAC 1193
+G C+ C GF G A P C
Sbjct: 838 TTGDHCEHCQEGFYGSALAPRPADKC 863
Score = 166 bits (420), Expect = 2e-40
Identities = 102/303 (33%), Positives = 125/303 (41%), Gaps = 71/303 (23%)
Query: 953 VCHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRC 1010
+C C GYTG CE+CAPG+ + + P C C C+ + CDP+TG C+ C
Sbjct: 672 ICSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQH------GTCDPNTGICV-C 724
Query: 1011 LHHTEGPHCAHCKPGFHGQ---AARQSCHRCTC---NLLGTNPQ-------QCP------ 1051
HHTEGP C C PGF+G C C C + T P+ CP
Sbjct: 725 SHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGR 784
Query: 1052 ------------------SPDQCH---------------CDPSSGQC-PCLPNVQGPSCD 1077
P CH CDP SG C CL N G C+
Sbjct: 785 RCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTGDHCE 844
Query: 1078 RCAPNFWNLT----SGHGCQPCACHP--SRARGPTCNEFTGQCHCRAGFGGRTCSECQEL 1131
C F+ C PC+CHP S + C+ TGQC C R CS C
Sbjct: 845 HCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPG 904
Query: 1132 HWG-DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190
+ PG C +C C G QCH TG C+CRPGV+G CD+C GF G + C
Sbjct: 905 FFDLQPGRGCRSCKCHPLGSQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGF--SIKGC 962
Query: 1191 HAC 1193
AC
Sbjct: 963 RAC 965
Score = 160 bits (405), Expect = 1e-38
Identities = 90/259 (34%), Positives = 124/259 (47%), Gaps = 29/259 (11%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C+C H+T G +CE+C + P+ G + C+ C C G + +C S
Sbjct: 720 GICVCSHHTEGPSCERCLPGFYGNPFA----GQADDCQPCPCPGQS-AC----TTIPESR 770
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDG---GRCD 424
V VC C GR CE+C F+ DP P C C C G+ D G CD
Sbjct: 771 EV---VCTHCPPGQRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCS--GNVDPNAVGNCD 825
Query: 425 SHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLG--CRRCQCNARGTVPGS 481
+SG C RC + G C+ C++GF+G +++ R C C C+ +G+V
Sbjct: 826 P--------LSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQ 877
Query: 482 TPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC 541
PCDP +G C C VT R C RC PG + L GCR C C G+ + QC TGQC
Sbjct: 878 MPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPG-RGCRSCKCHPLGSQEDQCHPKTGQC 936
Query: 542 HCRQHMVGRRCEQVQPGYF 560
CR + G+ C++ Q G+F
Sbjct: 937 TCRPGVTGQACDRCQLGFF 955
Score = 151 bits (381), Expect = 6e-36
Identities = 101/288 (35%), Positives = 123/288 (42%), Gaps = 35/288 (12%)
Query: 281 GNCFCYGHASEC--APAPGAPAHAEGMVHGACICKH---NTRGLNCEQCQDFYRDLPWRP 335
GN F G A +C P PG A +C H RG CE C D + P
Sbjct: 742 GNPFA-GQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRCEVCDDGFFGDPL-- 798
Query: 336 AEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS--GGVCDGCQHNTAGRHCELCRPFF 393
GH C +C+C G+ A GN G C C HNT G HCE C+ F
Sbjct: 799 GLFGHPQPCHQCQCSGNVDPN--------AVGNCDPLSGHCLRCLHNTTGDHCEHCQEGF 850
Query: 394 YRDPTKDLRDPAVCRSCDCDPMGS-QDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQC 452
Y R C C C P GS + CD V+GQC C HV C +C
Sbjct: 851 YGSALAP-RPADKCMPCSCHPQGSVSEQMPCDP--------VTGQCSCLPHVTARDCSRC 901
Query: 453 RDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL 512
GFF L GCR C+C+ G+ C P +G C C+ VTG+ CDRC G +G
Sbjct: 902 YPGFFDLQPGR--GCRSCKCHPLGSQEDQ--CHPKTGQCTCRPGVTGQACDRCQLGFFGF 957
Query: 513 SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
S + GCR C C GA QC E G C CR G +C++ +F
Sbjct: 958 S--IKGCRACRCSPLGAASAQCHE-NGTCVCRPGFEGYKCDRCHDNFF 1002
Score = 139 bits (349), Expect = 3e-32
Identities = 77/216 (35%), Positives = 111/216 (51%), Gaps = 19/216 (8%)
Query: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
+C+C+GH C D+A LA CQHNT G CE C PFF P A
Sbjct: 270 RCKCNGHASECGPDVAGQLACR---------CQHNTTGTDCERCLPFFQDRPWARGTAEA 320
Query: 406 VCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSISDR 464
C+ G + D + G G+C C++H G C++C++ F+ R
Sbjct: 321 AHECLPCNCSGRSEECTFDRELFRSTGH-GGRCHHCRDHTAGPHCERCQENFYHWD--PR 377
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDC 524
+ C+ C C + G++ CD ++G+C CK VTG CDRCLPG LS GCRPC C
Sbjct: 378 MPCQPCDCQSAGSL--HLQCD-DTGTCACKPTVTGWKCDRCLPGFHSLSEG--GCRPCTC 432
Query: 525 DVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
+ G+LD CD +G+C C++++ G C++ +PG F
Sbjct: 433 NPAGSLDT-CDPRSGRCPCKENVEGNLCDRCRPGTF 467
Score = 124 bits (311), Expect = 8e-28
Identities = 76/224 (33%), Positives = 98/224 (43%), Gaps = 36/224 (16%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGR--------CQLCECSGN 991
A+ C D + Q+ C C+ TG CE C P F D RP R C C CSG
Sbjct: 277 ASECGPD-VAGQLACRCQHNTTGTDCERCLP-FFQD--RPWARGTAEAAHECLPCNCSGR 332
Query: 992 IDPMDPDA----CDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNP 1047
+ D H G+C C HT GPHC C+ F+ R C C C G+
Sbjct: 333 SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDCQSAGSLH 392
Query: 1048 QQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTC 1107
QC +G C C P V G CDRC P F +L+ G GC+PC C+P+ + TC
Sbjct: 393 LQC---------DDTGTCACKPTVTGWKCDRCLPGFHSLSEG-GCRPCTCNPAGSL-DTC 441
Query: 1108 NEFTGQCHCRAGFGGRTCSECQELHWGDPGLQ------CHACDC 1145
+ +G+C C+ G C C+ G LQ C +C C
Sbjct: 442 DPRSGRCPCKENVEGNLCDRCRP---GTFNLQPHNPAGCSSCFC 482
Score = 117 bits (294), Expect = 8e-26
Identities = 85/256 (33%), Positives = 106/256 (41%), Gaps = 58/256 (22%)
Query: 832 QCSHEGALSSLCEKTSGQ--CLCRTGAFGLRCDRC----QRGQWGFPS------CRPCVC 879
+C G S +GQ C C+ G C+RC Q W + C PC C
Sbjct: 270 RCKCNGHASECGPDVAGQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEAAHECLPCNC 329
Query: 880 NGHADECNT---------HTGACLGCRDHTGGEHCERCIAGF-HGDPRLPYGGQCRPCPC 929
+G ++EC H G C CRDHT G HCERC F H DPR+P C+PC C
Sbjct: 330 SGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMP----CQPCDC 385
Query: 930 PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECS 989
A S H + C C+ TG +C+ C PG F S G R C +
Sbjct: 386 QS--------AGSLHL-QCDDTGTCACKPTVTGWKCDRCLPG-FHSLSEGGCRPCTCNPA 435
Query: 990 GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQ 1049
G++ D CDP +G+C C + EG C C+PG T NL NP
Sbjct: 436 GSL-----DTCDPRSGRC-PCKENVEGNLCDRCRPG-------------TFNLQPHNPAG 476
Query: 1050 CPSPDQCHCDPSSGQC 1065
C S C C S C
Sbjct: 477 CSS---CFCYGHSKVC 489
Score = 117 bits (293), Expect = 1e-25
Identities = 62/155 (40%), Positives = 79/155 (50%), Gaps = 11/155 (7%)
Query: 781 LPCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP-TGCQACQCSHEG 837
+PC C+PQGS+S + C+P GQC C P V R C C PG++ P GC++C+C G
Sbjct: 864 MPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSRCYPGFFDLQPGRGCRSCKCHPLG 923
Query: 838 ALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPCVCN--GHADECNTHTGAC 893
+ C +GQC CR G G CDRCQ G +GF CR C C+ G A G C
Sbjct: 924 SQEDQCHPKTGQCTCRPGVTGQACDRCQLGFFGFSIKGCRACRCSPLGAASAQCHENGTC 983
Query: 894 LGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCP 928
+ CR G C+RC F G C+ CP
Sbjct: 984 V-CRPGFEGYKCDRCHDNFF---LTADGTHCQQCP 1014
Score = 109 bits (273), Expect = 2e-23
Identities = 82/242 (33%), Positives = 110/242 (45%), Gaps = 40/242 (16%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD-FYRD-LPWRPAEDGH 340
C C G+ P A + + + C HNT G +CE CQ+ FY L RPA+
Sbjct: 810 CQCSGNVD-----PNAVGNCDPLSGHCLRCLHNTTGDHCEHCQEGFYGSALAPRPADK-- 862
Query: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
C C CH ++ + V+G C H TA R C C P F+ D
Sbjct: 863 ---CMPCSCHPQG-----SVSEQMPCDPVTGQ-CSCLPHVTA-RDCSRCYPGFF-----D 907
Query: 401 LRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLS 460
L+ CRSC C P+GSQ+ +C +GQC C+ V G C +C+ GFFG S
Sbjct: 908 LQPGRGCRSCKCHPLGSQED-QCHPK--------TGQCTCRPGVTGQACDRCQLGFFGFS 958
Query: 461 ISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCR 520
I GCR C+C+ G S C N G+C C+ G CDRC ++ L+ D C+
Sbjct: 959 IK---GCRACRCSPLGA--ASAQCHEN-GTCVCRPGFEGYKCDRC-HDNFFLTADGTHCQ 1011
Query: 521 PC 522
C
Sbjct: 1012 QC 1013
Score = 101 bits (252), Expect = 6e-21
Identities = 68/228 (29%), Positives = 95/228 (41%), Gaps = 23/228 (10%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQ-CLRCLHHTEGPHCAHCKPGFH----GQAARQS 1034
GGRC+ C+G+ PD GQ RC H+T G C C P F + ++
Sbjct: 268 GGRCK---CNGHASECGPDVA----GQLACRCQHNTTGTDCERCLPFFQDRPWARGTAEA 320
Query: 1035 CHRCT-CNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQGPSCDRCAPNFWNLTSGHGC 1092
H C CN G + + + G+C C + GP C+RC NF++ C
Sbjct: 321 AHECLPCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPC 380
Query: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRG-ID 1151
QPC C + + C++ TG C C+ G C C C C C+ G +D
Sbjct: 381 QPCDCQSAGSLHLQCDD-TGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLD 439
Query: 1152 TPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHPCHACFG 1195
T C +G C C+ V G CD+C G + P C C C+G
Sbjct: 440 T--CDPRSGRCPCKENVEGNLCDRCRPGTFNLQPHNPAGCSSCF-CYG 484
Score = 95.5 bits (236), Expect = 4e-19
Identities = 58/165 (35%), Positives = 76/165 (46%), Gaps = 23/165 (13%)
Query: 781 LPCQCNPQGSLSSECN---------PHGGQCL-CKPGVVGRRCDLCAPGYYGFGPT-GCQ 829
LPC C+ + S EC HGG+C C+ G C+ C +Y + P CQ
Sbjct: 325 LPCNCSGR---SEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQ 381
Query: 830 ACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP--SCRPCVCN--GHADE 885
C C G+L C+ T G C C+ G +CDRC G CRPC CN G D
Sbjct: 382 PCDCQSAGSLHLQCDDT-GTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT 440
Query: 886 CNTHTGACLGCRDHTGGEHCERCIAG-FHGDPRLPYGGQCRPCPC 929
C+ +G C C+++ G C+RC G F+ P P G C C C
Sbjct: 441 CDPRSGRC-PCKENVEGNLCDRCRPGTFNLQPHNPAG--CSSCFC 482
Score = 85.9 bits (211), Expect = 3e-16
Identities = 73/237 (30%), Positives = 96/237 (40%), Gaps = 50/237 (21%)
Query: 783 CQCNPQGSLSSECNPH-GGQ--CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGAL 839
C+CN +SEC P GQ C C+ G C+ C P ++ P + +HE L
Sbjct: 271 CKCNGH---ASECGPDVAGQLACRCQHNTTGTDCERCLP-FFQDRPWARGTAEAAHE-CL 325
Query: 840 SSLCEKTSGQCL-----------------CRTGAFGLRCDRCQRGQWGFP---SCRPCVC 879
C S +C CR G C+RCQ + + C+PC C
Sbjct: 326 PCNCSGRSEECTFDRELFRSTGHGGRCHHCRDHTAGPHCERCQENFYHWDPRMPCQPCDC 385
Query: 880 NGHAD---ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGS 935
+C+ TG C C+ G C+RC+ GFH L GG CRPC C P G
Sbjct: 386 QSAGSLHLQCD-DTGTC-ACKPTVTGWKCDRCLPGFHS---LSEGG-CRPCTCNPAGS-- 437
Query: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGN 991
+C D S + C C+ G C+ C PG F P P G C C C G+
Sbjct: 438 ----LDTC--DPRSGR--CPCKENVEGNLCDRCRPGTFNLQPHNPAG-CSSCFCYGH 485
Score = 79.0 bits (193), Expect = 4e-14
Identities = 64/246 (26%), Positives = 88/246 (35%), Gaps = 76/246 (30%)
Query: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSG 436
C G+ CE C P + R+ + A C C C+ G+ CD + +G
Sbjct: 675 CPTGYTGQFCESCAPGYKREMPQG-GPYASCVPCTCNQHGT-----CDPN--------TG 720
Query: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRL-GCRRCQC---NARGTVPGS----------- 481
C C H G C++C GF+G + + C+ C C +A T+P S
Sbjct: 721 ICVCSHHTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPG 780
Query: 482 ------------------------TPC-----------------DPNSGSCY-CKRLVTG 499
PC DP SG C C TG
Sbjct: 781 QRGRRCEVCDDGFFGDPLGLFGHPQPCHQCQCSGNVDPNAVGNCDPLSGHCLRCLHNTTG 840
Query: 500 RGCDRCLPGHWGLS---HDLLGCRPCDCDVGGALDPQ--CDEGTGQCHCRQHMVGRRCEQ 554
C+ C G +G + C PC C G++ Q CD TGQC C H+ R C +
Sbjct: 841 DHCEHCQEGFYGSALAPRPADKCMPCSCHPQGSVSEQMPCDPVTGQCSCLPHVTARDCSR 900
Query: 555 VQPGYF 560
PG+F
Sbjct: 901 CYPGFF 906
Score = 72.0 bits (175), Expect = 5e-12
Identities = 42/128 (32%), Positives = 51/128 (39%), Gaps = 11/128 (8%)
Query: 438 CRCKEHVVGTRCQQCRDGFFGLSISDR--LGCRRCQCNARGTVPGSTPCDPNSGSCYCKR 495
C C G C+ C G+ C C CN GT CDPN+G C C
Sbjct: 673 CSCPTGYTGQFCESCAPGYKREMPQGGPYASCVPCTCNQHGT------CDPNTGICVCSH 726
Query: 496 LVTGRGCDRCLPGHWG--LSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRRC 552
G C+RCLPG +G + C+PC C A + C HC GRRC
Sbjct: 727 HTEGPSCERCLPGFYGNPFAGQADDCQPCPCPGQSACTTIPESREVVCTHCPPGQRGRRC 786
Query: 553 EQVQPGYF 560
E G+F
Sbjct: 787 EVCDDGFF 794
Score = 67.8 bits (164), Expect = 9e-11
Identities = 38/104 (36%), Positives = 47/104 (45%), Gaps = 8/104 (7%)
Query: 748 QCHEEGLVPSK-TSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKP 806
QC + G K T C L +L G PC CNP GSL + C+P G+C CK
Sbjct: 394 QCDDTGTCACKPTVTGWKCDRCLPGFHSLSEGGCRPCTCNPAGSLDT-CDPRSGRCPCKE 452
Query: 807 GVVGRRCDLCAPGYYGF---GPTGCQACQCSHEGALSSLCEKTS 847
V G CD C PG + P GC +C C S +C T+
Sbjct: 453 NVEGNLCDRCRPGTFNLQPHNPAGCSSCFCYGH---SKVCASTA 493
Score = 48.9 bits (115), Expect = 4e-05
Identities = 22/70 (31%), Positives = 35/70 (50%), Gaps = 2/70 (2%)
Query: 763 EACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY- 821
+AC + G C+C+P G+ S++C+ G C+C+PG G +CD C ++
Sbjct: 945 QACDRCQLGFFGFSIKGCRACRCSPLGAASAQCH-ENGTCVCRPGFEGYKCDRCHDNFFL 1003
Query: 822 GFGPTGCQAC 831
T CQ C
Sbjct: 1004 TADGTHCQQC 1013
Score = 48.5 bits (114), Expect = 6e-05
Identities = 96/366 (26%), Positives = 158/366 (43%), Gaps = 56/366 (15%)
Query: 1446 AATADLALGRARHTQAELQRALAEGGSILSRVA-ETRRQASEAQQRAQAALDKANASRGQ 1504
AATA AL A +T L L EG RVA ET+R + Q QAA A R
Sbjct: 1174 AATAWRAL-LASNTSYALLWNLLEG-----RVALETQRDLEDRYQEVQAA---QKALRTA 1224
Query: 1505 VEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVR 1564
V + E + ++ +V+ Q GAD + L + AE + A A+ + V
Sbjct: 1225 VAEVLPEAESVLATVQ----QVGADTAPYLALLASPGALPQKSRAEDLGLKAKALEKTVA 1280
Query: 1565 SLADVDAILARTVGDVRRAE--------QLLQDARRARSWAEDEKQKA-------ETVQA 1609
S + ART+ +A +L Q+AR A + A Q A T+ A
Sbjct: 1281 SWQHMATEAARTLQTAAQATLRQTEPLTKLHQEARAALTQASSSVQAATVTVMGARTLLA 1340
Query: 1610 ALE--EAQRAQGIAQGAIR---GAVADT--RDTEQTLYQVQERMAGAERALSSAGERARQ 1662
LE + Q + Q A++ +V+D DT + Q + + A SSA ++ R+
Sbjct: 1341 DLEGMKLQFPRPKDQAALQRKADSVSDRLLADTRKKTKQAERMLGNAAPLSSSAKKKGRE 1400
Query: 1663 LDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQ 1722
+ L A+++A A+ +E +Q R QT +A ++ +Q
Sbjct: 1401 AEVL-----------------AKDSAKLAKALLRERKQAHRRASRLTSQT-QATLQQASQ 1442
Query: 1723 GVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRS 1782
VLA++AR ++L +EA + + Q+++E + E++ L A+L L+ ++
Sbjct: 1443 QVLASEARRQEL-EEAERVGAGLSEMEQQIRESRISLEKDIETLSELLARLGSLDTH-QA 1500
Query: 1783 VLQAIN 1788
QA+N
Sbjct: 1501 PAQALN 1506
>gi|38788416 laminin, alpha 1 precursor [Homo sapiens]
Length = 3075
Score = 289 bits (740), Expect = 1e-77
Identities = 141/394 (35%), Positives = 196/394 (49%), Gaps = 65/394 (16%)
Query: 850 CLCRTGAFGLRCDRCQRGQWGFPS------CRPCVCNGHADECNTHTGACLGCRDHTGGE 903
C C G G C+ C G + C+PC C+GHA ECN H G C+ C +T G
Sbjct: 709 CECPQGYTGTSCESCLSGYYRVDGILFGGICQPCECHGHAAECNVH-GVCIACAHNTTGV 767
Query: 904 HCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGL 963
HCE+C+ GF+G+P G C+PC CP S +F+ +CH ++ + + C GY+G
Sbjct: 768 HCEQCLPGFYGEPSRGTPGDCQPCACPLTIASN-NFSPTCHLNDGDEVVCDWCAPGYSGA 826
Query: 964 RCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCK 1023
CE CA G++G+P+ PG C C+CSGN+DP + CD TG+CL+CL +T+G HC C
Sbjct: 827 WCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSVTGECLKCLGNTDGAHCERCA 886
Query: 1024 PGFHGQA-ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
GF+G A ++C C C++ G++ CH + +G C C PNV G CD+C
Sbjct: 887 DGFYGDAVTAKNCRACECHVKGSHSA------VCHLE--TGLCDCKPNVTGQQCDQCLHG 938
Query: 1083 FWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGR------------------- 1123
++ L SGHGC+PC C + + C + GQCHC G G+
Sbjct: 939 YYGLDSGHGCRPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTP 997
Query: 1124 --------------------------TCSECQELHWG-DPGLQCHACDCDSRGIDTPQCH 1156
C EC++ HWG D + C AC+C G +C
Sbjct: 998 CDCPHTQNTCDPETGECVCPPHTQGVKCEECEDGHWGYDAEVGCQACNCSLVGSTHHRCD 1057
Query: 1157 RFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190
TGHC C+ G CDQC+ G+ FP C PC
Sbjct: 1058 VVTGHCQCKSKFGGRACDQCSLGYRD-FPDCVPC 1090
Score = 239 bits (611), Expect = 1e-62
Identities = 170/542 (31%), Positives = 243/542 (44%), Gaps = 72/542 (13%)
Query: 18 LRLGLLLSVLAATLAQAPAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPYC 77
+R G+LL +L AQ C + +PA +L ++ ++TCG GP+ +C
Sbjct: 1 MRGGVLLVLLLCVAAQ--------CRQRGLFPAILNLASNA--HISTNATCGEKGPEMFC 50
Query: 78 -IVSHLQDEK----KCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS---ENG 129
+V H+ +C +CD +P SH I WWQS +NG
Sbjct: 51 KLVEHVPGRPVRNPQCRICDGNSANPRERHPISHAIDGTNN---------WWQSPSIQNG 101
Query: 130 IPA--VTIQLDLEAEFHFTHLIMTFKTF-RPAAMLVERSADFGRTWHVYRYFSY---DCG 183
VTI LDL F ++I+ RP ++ERS D G T+ ++Y++ +C
Sbjct: 102 REYHWVTITLDLRQVFQVAYVIIKAANAPRPGNWILERSLD-GTTFSPWQYYAVSDSECL 160
Query: 184 ADFPGVPLAPP---RHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRIQNLL 240
+ + P P R D+V+C S YS + P GE I+ L P D S ++
Sbjct: 161 SRYNITPRRGPPTYRADDEVICTSYYSRLVPLEHGE-IHTSLINGRPSADDLSPKLLEFT 219
Query: 241 KITNLRVNLTRLHTLGDNLLD-PRREIRE-------KYYYALYELVVRGNCFCYGHASEC 292
+R+ L R+ TL +L+ RE +E +YYY++ ++ V G C CYGHAS C
Sbjct: 220 SARYIRLRLQRIRTLNADLMTLSHREPKELDPIVTRRYYYSIKDISVGGMCICYGHASSC 279
Query: 293 APAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGH 352
E C C+HNT G +C +C Y PWRP + C C CH
Sbjct: 280 P-------WDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNK 332
Query: 353 THSCHFDMAVYLASGNVS-------GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
C++D +V +++ GGVC C NT G +CE C +YR +
Sbjct: 333 AKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDE 392
Query: 406 VCRSCDCDPMGSQDGG--RCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISD 463
CR C+CDP+GS + D H D G GQC CKE G +C +C+ G+ D
Sbjct: 393 PCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGY-----KD 447
Query: 464 RLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSH-DLLGCRPC 522
C C CN GS +P +G C CK V G+ CDRC PG + L + GC C
Sbjct: 448 YPTCVSCGCNP----VGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSEC 503
Query: 523 DC 524
C
Sbjct: 504 FC 505
Score = 190 bits (483), Expect = 9e-48
Identities = 203/762 (26%), Positives = 292/762 (38%), Gaps = 136/762 (17%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD-FYRDLPWRPAEDGH 340
C C G+ P H + V G C+ C NT G +CE+C D FY D
Sbjct: 849 CDCSGNVD-----PSEAGHCDS-VTGECLKCLGNTDGAHCERCADGFYGDAVT------- 895
Query: 341 SHACRKCECH---GHTHSCHFDMAVYLASGNVSGGVCDGCQHN----TAGRHCELCRPFF 393
+ CR CECH H+ CH + + NV+G CD C H +G C C
Sbjct: 896 AKNCRACECHVKGSHSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSGHGCRPCNCSV 955
Query: 394 YRDPTKDLRDPAVC--------RSCDCDPMGS---QDGG--RCDS-HDDPALGLVSGQCR 439
+ D C + CD G QDG CD H +G+C
Sbjct: 956 AGSVSDGCTDEGQCHCVPGVAGKRCDRCAHGFYAYQDGSCTPCDCPHTQNTCDPETGECV 1015
Query: 440 CKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTG 499
C H G +C++C DG +G +GC+ C C+ G+ CD +G C CK G
Sbjct: 1016 CPPHTQGVKCEECEDGHWGYDAE--VGCQACNCSLVGSTHHR--CDVVTGHCQCKSKFGG 1071
Query: 500 RGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCD---------EGTGQCHCRQHMVGR 550
R CD+C G+ D C PCDCD+ G C+ E TG C C++++ G
Sbjct: 1072 RACDQCSLGY----RDFPDCVPCDCDLRGTSGDACNLEQGLCGCVEETGACPCKENVFGP 1127
Query: 551 RCEQVQPGYFRPFLDHLIWEAEDTRGQVLDVVERLVTPGETPSWTGSG--FVRLQEGQTL 608
+C + + G F D+ + + + + L TP GS +R+ L
Sbjct: 1128 QCNECREGTFALRADNPLGCSPCFCSGLSHLCSELEDYVRTPVTLGSDQPLLRVVSQSNL 1187
Query: 609 EFLVASV-PKAMDYDL-------LLRLEP---QVPEQWAELELIV---QRPGPVPAHSLC 654
V +A D+ L +R EP ++P+Q+ +L+ + V +SL
Sbjct: 1188 RGTTEGVYYQAPDFLLDAATVRQHIRAEPFYWRLPQQFQGDQLMAYGGKLKYSVAFYSLD 1247
Query: 655 G----HLVPKDDRIQGTLQPHARYLIFPNP---VCLEPGISYKLHLKLVRTGGSAQPETP 707
G + P+ G ++ Y+ P P V E ++ + + S +P T
Sbjct: 1248 GVGTSNFEPQVLIKGGRIRKQVIYMDAPAPENGVRQEQEVAMRENFWKYFNSVSEKPVTR 1307
Query: 708 YSGPGLLIDSLVLLPRVLVLEMFSGGDAAALERQATFERYQCHEEGLVPSKTSPSEACAP 767
+L D + +L+ + G + + E G K P E A
Sbjct: 1308 EDFMSVLSD----IEYILIKASYGQGLQQSRISDISME------VGRKAEKLHPEEEVAS 1357
Query: 768 LLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP-- 825
LL + C C P G++ C C PG R L A G P
Sbjct: 1358 LLEN-----------CVC-PPGTVGFSCQD------CAPGY--HRGKLPAGSDRGPRPLV 1397
Query: 826 TGCQACQCSHEGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWG-----FPSCRPCVC 879
C C C++ S C+ +G+CL C G CD C G +G C C C
Sbjct: 1398 APCVPCSCNNH---SDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC 1454
Query: 880 -----NGHADEC---NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-P 930
+ C H C C G+HCERC + ++G+P+ P GG C+ C C P
Sbjct: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTP-GGSCQKCDCNP 1513
Query: 931 EGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
G S H D C CR G +GLRC+ C P H
Sbjct: 1514 HG---------SVHGDCDRTSGQCVCRLGASGLRCDECEPRH 1546
Score = 174 bits (440), Expect = 9e-43
Identities = 100/281 (35%), Positives = 144/281 (51%), Gaps = 37/281 (13%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
C C+GHA+EC VHG CI C HNT G++CEQC + P R G
Sbjct: 742 CECHGHAAEC------------NVHGVCIACAHNTTGVHCEQCLPGFYGEPSR----GTP 785
Query: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDL 401
C+ C C S +F +L G+ VCD C +G CE C +Y +PT
Sbjct: 786 GDCQPCACPLTIASNNFSPTCHLNDGDEV--VCDWCAPGYSGAWCERCADGYYGNPTVPG 843
Query: 402 RDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGL 459
C CDC + + G CDS V+G+C +C + G C++C DGF+G
Sbjct: 844 ES---CVPCDCSGNVDPSEAGHCDS--------VTGECLKCLGNTDGAHCERCADGFYGD 892
Query: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC 519
+++ + CR C+C+ +G+ S C +G C CK VTG+ CD+CL G++GL GC
Sbjct: 893 AVTAK-NCRACECHVKGS--HSAVCHLETGLCDCKPNVTGQQCDQCLHGYYGLDSG-HGC 948
Query: 520 RPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
RPC+C V G++ C + GQCHC + G+RC++ G++
Sbjct: 949 RPCNCSVAGSVSDGCTD-EGQCHCVPGVAGKRCDRCAHGFY 988
Score = 132 bits (331), Expect = 4e-30
Identities = 76/254 (29%), Positives = 107/254 (42%), Gaps = 25/254 (9%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDG--HSHACRKCECHGHTHSCHFDMAVYLASG 367
C C G +CE C Y + DG C+ CECHGH C+
Sbjct: 709 CECPQGYTGTSCESCLSGYYRV------DGILFGGICQPCECHGHAAECNVH-------- 754
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
GVC C HNT G HCE C P FY +P++ P C+ C C + + H
Sbjct: 755 ----GVCIACAHNTTGVHCEQCLPGFYGEPSRGT--PGDCQPCACPLTIASNNFSPTCHL 808
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
+ +V C G C++C DG++G C C C+ + CD
Sbjct: 809 NDGDEVVCDWCA--PGYSGAWCERCADGYYGNPTVPGESCVPCDCSGNVDPSEAGHCDSV 866
Query: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQH 546
+G C C G C+RC G +G + CR C+C V G+ C TG C C+ +
Sbjct: 867 TGECLKCLGNTDGAHCERCADGFYGDAVTAKNCRACECHVKGSHSAVCHLETGLCDCKPN 926
Query: 547 MVGRRCEQVQPGYF 560
+ G++C+Q GY+
Sbjct: 927 VTGQQCDQCLHGYY 940
Score = 126 bits (317), Expect = 2e-28
Identities = 70/225 (31%), Positives = 99/225 (44%), Gaps = 44/225 (19%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRC 861
C+C PG VG C CAPGY H G L + ++ +
Sbjct: 1362 CVCPPGTVGFSCQDCAPGY--------------HRGKLPAGSDRGPRPLVA--------- 1398
Query: 862 DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
C PC CN H+D C+ +TG CL C D+T G+HC+ C +G++G
Sbjct: 1399 -----------PCVPCSCNNHSDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKV-TGSA 1446
Query: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
C C CP P + F+ +C + C GY G CE C+ ++G+P PGG
Sbjct: 1447 SDCALCACPHSPPAS--FSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGG 1504
Query: 982 RCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKP 1024
CQ C+C+ G++ CD +GQC+ C G C C+P
Sbjct: 1505 SCQKCDCNPHGSVH----GDCDRTSGQCV-CRLGASGLRCDECEP 1544
Score = 112 bits (280), Expect = 3e-24
Identities = 110/495 (22%), Positives = 192/495 (38%), Gaps = 80/495 (16%)
Query: 940 ATSCHQDEYSQQIV--CHCRAGYTGLRCEACAPGHFGDPSRPGGR---------CQLCEC 988
A H +E ++ C C G G C+ CAPG+ G C C C
Sbjct: 1346 AEKLHPEEEVASLLENCVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSC 1405
Query: 989 SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQ--AARQSCHRCTCNLLGTN 1046
+ + D CDP+TG+CL C +T G HC C G++G+ + C C C
Sbjct: 1406 NNH-----SDTCDPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALCAC------ 1454
Query: 1047 PQQCPSPDQCHC----DPSSGQCPCLPNVQGPSCDRCAPNFWN--LTSGHGCQPCACHPS 1100
P P+ C D CL +G C+RC+ +++ T G CQ C C+P
Sbjct: 1455 PHSPPASFSPTCVLEGDHDFRCDACLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPH 1514
Query: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTG 1160
+ C+ +GQC CR G G C EC+ H C +CD + G+
Sbjct: 1515 GSVHGDCDRTSGQCVCRLGASGLRCDECEPRHI-LMETDCVSCDDECVGV---------- 1563
Query: 1161 HCSCRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQ 1220
+ + + +GI P + + + + +Q+ + E ++L +
Sbjct: 1564 ---LLNDLDEIGDAVLSLNLTGIIPVPYGILSNLENTTKYLQESLLK----ENMQKDLGK 1616
Query: 1221 TGVLGAFESSFWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLE 1280
+ G E + ++Q+KL AST ++ ATE + +E + + +L+
Sbjct: 1617 IKLEGVAEETD-NLQKKL----------TRMLASTQKVNRATERIFKESQDLAIAIERLQ 1665
Query: 1281 ADLTDVQDENFNANHALSGLERDRLALNLTLRQLDQH----LDLLKHSNFLGAYDSIRHA 1336
+T++ E N L+ D L N TL+ + Q+ L++++ +F +
Sbjct: 1666 MSITEIM-EKTTLNQT---LDEDFLLPNSTLQNMQQNGTSLLEIMQIRDFTQLH------ 1715
Query: 1337 HSQSAEAERRANTSALA-----VPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALG 1391
Q+A E +A L+ P+ + ++ + + + A
Sbjct: 1716 --QNATLELKAAEDLLSQIQENYQKPLEELEVLKEAASHVLSKHNNELKAAEALVREAEA 1773
Query: 1392 KLSAHTHTLSLTDIN 1406
K+ H L + + N
Sbjct: 1774 KMQESNHLLLMVNAN 1788
Score = 97.8 bits (242), Expect = 8e-20
Identities = 66/240 (27%), Positives = 92/240 (38%), Gaps = 44/240 (18%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHA----CRKCECHGHTHSCHFDMAVYLA 365
C+C T G +C+ C Y D C C C+ H+ +C
Sbjct: 1362 CVCPPGTVGFSCQDCAPGYHRGKLPAGSDRGPRPLVAPCVPCSCNNHSDTC--------- 1412
Query: 366 SGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGS-------- 417
+ + G C C NTAG HC++C +Y T D A+C +C P S
Sbjct: 1413 --DPNTGKCLNCGDNTAGDHCDVCTSGYYGKVTGSASDCALC-ACPHSPPASFSPTCVLE 1469
Query: 418 -QDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARG 476
RCD+ C G C++C ++G + C++C CN G
Sbjct: 1470 GDHDFRCDA--------------CLLGYEGKHCERCSSSYYGNPQTPGGSCQKCDCNPHG 1515
Query: 477 TVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDE 536
+V G CD SG C C+ +G CD C P H + D C CD + G L DE
Sbjct: 1516 SVHGD--CDRTSGQCVCRLGASGLRCDECEPRHILMETD---CVSCDDECVGVLLNDLDE 1570
Score = 95.9 bits (237), Expect = 3e-19
Identities = 66/242 (27%), Positives = 103/242 (42%), Gaps = 49/242 (20%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD--LRDP 404
C C+GH SC +D C C+HNT G C C P +++ P + +
Sbjct: 270 CICYGHASSCPWDETTKKLQ-------CQ-CEHNTCGESCNRCCPGYHQQPWRPGTVSSG 321
Query: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGL------VSGQCR-------CKEHVVGTRCQQ 451
C +C+C D + D ++ +GQ R C ++ +G C+
Sbjct: 322 NTCEACNCHNKAK------DCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCET 375
Query: 452 CRDGFFG---LSISDRLGCRRCQCNARGTVPGSTPCDP---------NSGSCYCKRLVTG 499
C DG++ +S + CR C C+ G++ D G C CK TG
Sbjct: 376 CIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTG 435
Query: 500 RGCDRCLPGHWGLSHDLLGCRPCDCD-VGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPG 558
CDRC G+ D C C C+ VG A D C TG C C++++ G+ C++ +PG
Sbjct: 436 EKCDRCQLGY----KDYPTCVSCGCNPVGSASDEPC---TGPCVCKENVEGKACDRCKPG 488
Query: 559 YF 560
++
Sbjct: 489 FY 490
Score = 87.4 bits (215), Expect = 1e-16
Identities = 53/152 (34%), Positives = 73/152 (48%), Gaps = 25/152 (16%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYYG------FGPTGCQACQCSHEGALSSLCEKTS---- 847
GG C+ C +G C+ C GYY + C+ C C G+LSS+C K
Sbjct: 358 GGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSVCIKDDLHSD 417
Query: 848 -------GQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCN--GHADECNTHTGACLGCRD 898
GQC C+ G G +CDRCQ G +P+C C CN G A + TG C+ C++
Sbjct: 418 LHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCGCNPVGSASD-EPCTGPCV-CKE 475
Query: 899 HTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
+ G+ C+RC GF+ + P G C C C
Sbjct: 476 NVEGKACDRCKPGFYNLKEKNPRG--CSECFC 505
Score = 85.1 bits (209), Expect = 6e-16
Identities = 58/230 (25%), Positives = 81/230 (35%), Gaps = 72/230 (31%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPG-----GRCQLCECSGNIDP 994
A+SC DE ++++ C C G C C PG+ P RPG C+ C C
Sbjct: 276 ASSCPWDETTKKLQCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKD 335
Query: 995 MDPDACDPHT-------------GQCLRCLHHTEGPHCAHCKPGFH-----GQAARQSCH 1036
D G C+ CL +T G +C C G++ + C
Sbjct: 336 CYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCR 395
Query: 1037 RCTCNLLGT------------------NPQQCPSPD---------------------QCH 1057
C C+ +G+ P QCP + C
Sbjct: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPTCVSCG 455
Query: 1058 C--------DPSSGQCPCLPNVQGPSCDRCAPNFWNL--TSGHGCQPCAC 1097
C +P +G C C NV+G +CDRC P F+NL + GC C C
Sbjct: 456 CNPVGSASDEPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Score = 84.0 bits (206), Expect = 1e-15
Identities = 66/246 (26%), Positives = 94/246 (38%), Gaps = 42/246 (17%)
Query: 985 LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAAR-------QSCHR 1037
+C C G+ D QC +C H+T G C C PG+H Q R +C
Sbjct: 269 MCICYGHASSCPWDETTKKL-QC-QCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEA 326
Query: 1038 CTCNLLGTN-------PQQCPSPDQCHCDPSSGQC-PCLPNVQGPSCDRCAPNFW----- 1084
C C+ + +Q S + G C CL N G +C+ C ++
Sbjct: 327 CNCHNKAKDCYYDESVAKQKKSLNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKV 386
Query: 1085 NLTSGHGCQPCACHPSRARGPTC-----------NEFTGQCHCRAGFGGRTCSECQELHW 1133
+ C+PC C P + C + GQC C+ G+ G C CQ +
Sbjct: 387 SPYEDEPCRPCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYK 446
Query: 1134 GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHP 1189
P C +C C+ G + + TG C C+ V G CD+C GF + C
Sbjct: 447 DYP--TCVSCGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSE 502
Query: 1190 CHACFG 1195
C CFG
Sbjct: 503 CF-CFG 507
Score = 81.6 bits (200), Expect = 6e-15
Identities = 45/123 (36%), Positives = 59/123 (47%), Gaps = 20/123 (16%)
Query: 782 PCQCNPQGSLSSEC-----------NPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQA 830
PC C+P GSLSS C GQC CK G G +CD C GY + PT C +
Sbjct: 396 PCNCDPVGSLSSVCIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDY-PT-CVS 453
Query: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHADE 885
C C+ G+ S E +G C+C+ G CDRC+ G + C C C G +D
Sbjct: 454 CGCNPVGSASD--EPCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSDV 511
Query: 886 CNT 888
C++
Sbjct: 512 CSS 514
Score = 67.0 bits (162), Expect = 2e-10
Identities = 59/239 (24%), Positives = 81/239 (33%), Gaps = 63/239 (26%)
Query: 801 QCLCKPGVVGRRCDLCAPGYY------GFGPTG--CQACQCSHEG---------ALSSLC 843
QC C+ G C+ C PGY+ G +G C+AC C ++ A
Sbjct: 289 QCQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCHNKAKDCYYDESVAKQKKS 348
Query: 844 EKTSGQ------CL-CRTGAFGLRCDRCQRGQWG--------FPSCRPCVCNG------- 881
T+GQ C+ C G+ C+ C G + CRPC C+
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRPHKVSPYEDEPCRPCNCDPVGSLSSV 408
Query: 882 ------HADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPG 934
H+D N C++ GE C+RC G+ P C C C P G
Sbjct: 409 CIKDDLHSDLHNGKQPGQCPCKEGYTGEKCDRCQLGYKDYPT------CVSCGCNPVGSA 462
Query: 935 SQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
S C C+ G C+ C PG + + C C C G D
Sbjct: 463 SDEPCTGPCV-----------CKENVEGKACDRCKPGFYNLKEKNPRGCSECFCFGVSD 510
Score = 58.9 bits (141), Expect = 4e-08
Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 8/74 (10%)
Query: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQACQC 833
Y + C CNP GS S E P G C+CK V G+ CD C PG+Y P GC C C
Sbjct: 448 YPTCVSCGCNPVGSASDE--PCTGPCVCKENVEGKACDRCKPGFYNLKEKNPRGCSECFC 505
Query: 834 SHEGALSSLCEKTS 847
+S +C S
Sbjct: 506 F---GVSDVCSSLS 516
Score = 52.4 bits (124), Expect = 4e-06
Identities = 23/57 (40%), Positives = 30/57 (52%), Gaps = 1/57 (1%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGAL 839
C CNP GS+ +C+ GQC+C+ G G RCD C P + T C +C G L
Sbjct: 1509 CDCNPHGSVHGDCDRTSGQCVCRLGASGLRCDECEPRHI-LMETDCVSCDDECVGVL 1564
Score = 39.3 bits (90), Expect = 0.035
Identities = 29/95 (30%), Positives = 37/95 (38%), Gaps = 24/95 (25%)
Query: 491 CYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPCDCDVGGALDPQCDE-------- 536
C C+ G C+RC PG+ W G C C+C A D DE
Sbjct: 290 CQCEHNTCGESCNRCCPGYHQQPWRPGTVSSGNTCEACNCH-NKAKDCYYDESVAKQKKS 348
Query: 537 --------GTGQC-HCRQHMVGRRCEQVQPGYFRP 562
G G C +C Q+ +G CE GY+RP
Sbjct: 349 LNTAGQFRGGGVCINCLQNTMGINCETCIDGYYRP 383
>gi|219842266 usherin isoform B [Homo sapiens]
Length = 5202
Score = 271 bits (694), Expect = 3e-72
Identities = 169/539 (31%), Positives = 260/539 (48%), Gaps = 72/539 (13%)
Query: 51 TGDLLVGRADRLTASSTCGLNGPQP--------YCIVSHLQDEKKCFLCDSRRPFSARDN 102
+GDLL RL A S C G P YCI + D D+R +R N
Sbjct: 290 SGDLL-----RLHAQSHCRCPGSHPRVHPLAQRYCIPNDAGDT-----ADNR---VSRLN 336
Query: 103 PHSHRIQ-----NVVTSFAPQRRAAWWQSENGIPAVTIQLDLE-AEFHFTHLIMTFKTFR 156
P +H + +V TS+ Q G VTI +DLE ++ ++I+ F + +
Sbjct: 337 PEAHPLSFVNDNDVGTSWVSNVFTNITQLNQG---VTISVDLENGQYQVFYIIIQFFSPQ 393
Query: 157 PAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGE 216
P + ++R + W ++YF+ +CGA G+ D V + S P + G
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAF--GMKNNGDLEKPDSVNCLQLSNFTPYSRGN 451
Query: 217 VIYRVLDPAIPIPDPYSS-----RIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYY 271
V + +L P Y++ +Q +K T +R + + + ++ R Y
Sbjct: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR-----Y 506
Query: 272 YALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHN--TRGLNCEQCQDFYR 329
YA+ E+ + G C C+GHA C P C+C T GL+C++C Y
Sbjct: 507 YAVDEITISGRCQCHGHADNC-DTTSQPYR--------CLCSQESFTEGLHCDRCLPLYN 557
Query: 330 DLPWRPAEDGHSHACRKCECHGHTHSCHFDMAV------YLASGNVSGGVCDGCQHNTAG 383
D P+R + ++ C+ C+C+ H+ SCH++++V + G GGVCD C+HNT G
Sbjct: 558 DKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGG---GGVCDDCEHNTTG 614
Query: 384 RHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG-RCDSHDDPALGLVSGQCRCKE 442
R+CELC+ +F+R D VC+ CDCD +G+++G CD + GQC CK
Sbjct: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKR 666
Query: 443 HVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
HV G +C QC++GF+ L D GC C CN GTV G C NSG C CK V G C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 503 DRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
D C G L S + +GC PC C++ G+++ C+ +GQC C++ G +C+ + ++
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY 785
Score = 241 bits (615), Expect = 5e-63
Identities = 141/420 (33%), Positives = 188/420 (44%), Gaps = 49/420 (11%)
Query: 782 PCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQACQCSHE 836
PC C+ G+ + C+ GGQC CK V GR+C+ C G+Y P GC C C+
Sbjct: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699
Query: 837 GALSS--LCEKTSGQCLCRTGAFGLRCDRCQRG-----QWGFPSCRPCVCNGHADE---C 886
G + C + SGQC C+ GLRCD C G + C PC CN H C
Sbjct: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC 759
Query: 887 NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEG---PGSQRHFATSC 943
N H+G C C+ G C+ C F+G C+ C C PG+ + T
Sbjct: 760 NPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDTAGSLPGTVCNAKTG- 813
Query: 944 HQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPH 1003
C C+ G +C C G+F C C C C+
Sbjct: 814 ---------QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 1004 TGQCLRCLHHTEGPHCAHCKPGFHGQAAR--QSCHRCTCNLLGTNPQQCPSPDQCHCDPS 1061
TGQC C G C C+P + Q C C C+ LGT P CDP
Sbjct: 865 TGQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI-------CDPI 916
Query: 1062 SGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCR-A 1118
SGQC C+PN QG C++C P F+ ++ G+ GC PC+CH + A CN TGQC C+ A
Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDA 975
Query: 1119 GFGGRTCSECQELHWG-DPGL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176
G+ C +C++ ++G DP +C C+C G CH TG C C+ V+G +CD C
Sbjct: 976 SIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 216 bits (550), Expect = 2e-55
Identities = 123/378 (32%), Positives = 178/378 (47%), Gaps = 32/378 (8%)
Query: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYY- 821
C +L L +G PC CN G++ + C+ + GQC CK V+G RCD C G+
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735
Query: 822 --GFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPC 877
F GC+ CQC+ G+++ C SGQC C+ A GL+CD C+ +G +C+ C
Sbjct: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Query: 878 VCNGHAD----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
C+ CN TG C+ C+ + G C +C+ G + R C PC C +
Sbjct: 796 DCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK-- 851
Query: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
+ + C++ C C+ G TGLRC C P + CQ+CEC ++
Sbjct: 852 TGTINGSLLCNKSTGQ----CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD-SLG 906
Query: 994 PMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFH-GQAARQSCHRCTCNLLGTNPQQCPS 1052
+ CDP +GQCL C+ + +G C C+PGF+ C C+C+ G C S
Sbjct: 907 TLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNS 965
Query: 1053 PDQCHCDPSSGQCPCL-PNVQGPSCDRCAPNFWNLTSGHG-CQPCACHPSRARGPTCNEF 1110
+GQC C ++ G CD+C +++ G CQPC CH S A TC+
Sbjct: 966 --------LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLV 1017
Query: 1111 TGQCHCRAGFGGRTCSEC 1128
TGQC C+ G C C
Sbjct: 1018 TGQCFCKQFVTGSKCDAC 1035
Score = 192 bits (487), Expect = 3e-48
Identities = 138/454 (30%), Positives = 193/454 (42%), Gaps = 68/454 (14%)
Query: 782 PCQCNPQGSLSSECNPH--------------GGQCL-CKPGVVGRRCDLCAPGYY---GF 823
PCQCN S S C+ + GG C C+ GR C+LC ++ G
Sbjct: 574 PCQCN---SHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630
Query: 824 GPTG---CQACQCSHEGAL--SSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS----- 873
P+ C+ C C G S LC++ GQC C+ G +C++CQ G +
Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDG 690
Query: 874 CRPCVCN--GHAD---ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCP 928
C PC CN G D C+ ++G C C+ + G C+ C GF G C PC
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVG-CEPCQ 748
Query: 929 CPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCEC 988
C H + + + +S Q C C+ GL+C+ C +G C+ C+C
Sbjct: 749 C------NLHGSVNKFCNPHSGQ--CECKKEAKGLQCDTCRENFYGLDVT---NCKACDC 797
Query: 989 SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS--CHRCTCNLLGTN 1046
+ C+ TGQC+ C + EG C C G S C C C+ GT
Sbjct: 798 D-TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT- 854
Query: 1047 PQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHP-SRAR 1103
C+ S+GQCPC V G C++C P+ +NLT + CQ C C
Sbjct: 855 -----INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 1104 GPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPG--LQCHACDCDSRGIDTPQCHRFTGH 1161
G C+ +GQC C GR C++CQ + PG C C C + G C+ TG
Sbjct: 910 GTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQ 969
Query: 1162 CSCRPG-VSGVRCDQCARGFSGIFP---ACHPCH 1191
C C+ ++G RCDQC + G P C PC+
Sbjct: 970 CVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCN 1003
Score = 176 bits (445), Expect = 2e-43
Identities = 141/495 (28%), Positives = 194/495 (39%), Gaps = 92/495 (18%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPG--VVGRRCDLCAPGY-----------YGFGPTGCQ 829
CQC+ + + +CLC G CD C P Y Y F C+
Sbjct: 518 CQCHGHAD-NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CK 573
Query: 830 ACQCSHEGALSSLCEKT--------------SGQCL-CRTGAFGLRCDRCQ----RGQWG 870
CQC+ S C G C C G C+ C+ R
Sbjct: 574 PCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630
Query: 871 FPS----CRPCVCNGHADE-----CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
PS C+PC C+ C+ G C C+ H G C +C GF+ L
Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
G C PC C +CHQ+ C C+A GLRC+ C G S
Sbjct: 690 G-CSPCNCNTSGTVDGDI--TCHQNSGQ----CKCKANVIGLRCDHCNFGFKFLRSFNDV 742
Query: 982 RCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039
C+ C+C+ G+++ C+PH+GQC C +G C C+ F+G +C C
Sbjct: 743 GCEPCQCNLHGSVNKF----CNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT-NCKACD 796
Query: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHG--CQPCAC 1097
C+ G+ P C+ +GQC C PNV+G C++C + L + C PC C
Sbjct: 797 CDTAGSLPGTV-------CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Query: 1098 HPSRARGPT--CNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDCDSRG-ID 1151
+ + CN+ TGQC C+ G G C++C+ + D C C+CDS G +
Sbjct: 850 DKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 1152 TPQCHRFTGHCSCRPGVSGVRCDQCARGF---SGIFPACHPC---------HACFG-DWD 1198
C +G C C P G RC+QC GF G C PC H C
Sbjct: 910 GTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQ 969
Query: 1199 RVVQDLAARTQRLEQ 1213
V QD + QR +Q
Sbjct: 970 CVCQDASIAGQRCDQ 984
Score = 150 bits (379), Expect = 1e-35
Identities = 87/255 (34%), Positives = 122/255 (47%), Gaps = 30/255 (11%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C CK N GL C+ C ++ L + C C+C+ H F
Sbjct: 713 GQCKCKANVIGLRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFC-------- 759
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
N G C+ C+ G C+ CR FY D C++CDCD GS G C++
Sbjct: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAK- 811
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
+GQC CK +V G +C +C +G F L ++ C C C+ GT+ GS C+ +
Sbjct: 812 -------TGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHD-LLGCRPCDCDVGGALDPQ-CDEGTGQCHCRQ 545
+G C CK VTG C++C P + L+ D C+ C+CD G L CD +GQC C
Sbjct: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 546 HMVGRRCEQVQPGYF 560
+ GRRC Q QPG++
Sbjct: 925 NRQGRRCNQCQPGFY 939
Score = 144 bits (363), Expect = 8e-34
Identities = 84/262 (32%), Positives = 122/262 (46%), Gaps = 44/262 (16%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C CK +GL C+ C++ + L C+ C+C +G
Sbjct: 764 GQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD--------------TAG 801
Query: 368 NVSGGVCDG------CQHNTAGRHCELCRP--FFYRDPTKDLRDPAVCRSCDCDPMGSQD 419
++ G VC+ C+ N GR C C F+ R L C C+CD G+ +
Sbjct: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTIN 856
Query: 420 GGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP 479
G + +GQC CK V G RC QC + L+I + C+ C+C++ GT+P
Sbjct: 857 GSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 480 GSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTG 539
G T CDP SG C C GR C++C PG + + GC PC C GA++ C+ TG
Sbjct: 910 G-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTG 968
Query: 540 QCHCRQ-HMVGRRCEQVQPGYF 560
QC C+ + G+RC+Q + YF
Sbjct: 969 QCVCQDASIAGQRCDQCKDHYF 990
Score = 140 bits (352), Expect = 1e-32
Identities = 97/352 (27%), Positives = 152/352 (43%), Gaps = 39/352 (11%)
Query: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRK 346
A +C A P G CICK N G C +C + FY +S C
Sbjct: 794 ACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLP 846
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
C C T + + + N S G C C+ G C C P Y + +
Sbjct: 847 CNCD-KTGTINGSLLC-----NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH--- 896
Query: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG 466
C+ C+CD +G+ G CD +SGQC C + G RC QC+ GF+ +S + G
Sbjct: 897 CQMCECDSLGTLPGTICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 467 CRRCQCNARGTVPGSTPCDPNSGSCYCKRL-VTGRGCDRCLPGHWGLSHDLLGCRPCDCD 525
C C C+ G V + C+ +G C C+ + G+ CD+C ++G C+PC+C
Sbjct: 948 CLPCSCHTTGAV--NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005
Query: 526 VGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLI------WEAEDTRGQV- 578
+ GAL+ C TGQC C+Q + G +C+ P +++L+ ++ RGQV
Sbjct: 1006 LSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQ 1065
Query: 579 -LDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEP 629
+ +P ++P+ + L++G + P ++ Y L L P
Sbjct: 1066 SSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLP 1117
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 27/115 (23%)
Query: 469 RCQCNARGTVPGSTPCDPNSGS--CYCKR--LVTGRGCDRCLPGH------WGLSHDLLG 518
RCQC+ + CD S C C + G CDRCLP + G
Sbjct: 517 RCQCHGH-----ADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN 571
Query: 519 CRPCDCDVGG-------ALDPQCDE----GTGQCH-CRQHMVGRRCEQVQPGYFR 561
C+PC C+ ++DP E G G C C + GR CE + +FR
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFR 626
>gi|219842259 usherin isoform A [Homo sapiens]
Length = 1546
Score = 271 bits (694), Expect = 3e-72
Identities = 169/539 (31%), Positives = 260/539 (48%), Gaps = 72/539 (13%)
Query: 51 TGDLLVGRADRLTASSTCGLNGPQP--------YCIVSHLQDEKKCFLCDSRRPFSARDN 102
+GDLL RL A S C G P YCI + D D+R +R N
Sbjct: 290 SGDLL-----RLHAQSHCRCPGSHPRVHPLAQRYCIPNDAGDT-----ADNR---VSRLN 336
Query: 103 PHSHRIQ-----NVVTSFAPQRRAAWWQSENGIPAVTIQLDLE-AEFHFTHLIMTFKTFR 156
P +H + +V TS+ Q G VTI +DLE ++ ++I+ F + +
Sbjct: 337 PEAHPLSFVNDNDVGTSWVSNVFTNITQLNQG---VTISVDLENGQYQVFYIIIQFFSPQ 393
Query: 157 PAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPPRHWDDVVCESRYSEIEPSTEGE 216
P + ++R + W ++YF+ +CGA G+ D V + S P + G
Sbjct: 394 PTEIRIQRKKENSLDWEDWQYFARNCGAF--GMKNNGDLEKPDSVNCLQLSNFTPYSRGN 451
Query: 217 VIYRVLDPAIPIPDPYSS-----RIQNLLKITNLRVNLTRLHTLGDNLLDPRREIREKYY 271
V + +L P Y++ +Q +K T +R + + + ++ R Y
Sbjct: 452 VTFSILTPGPNYRPGYNNFYNTPSLQEFVKATQIRFHFHGQYYTTETAVNLRHR-----Y 506
Query: 272 YALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHN--TRGLNCEQCQDFYR 329
YA+ E+ + G C C+GHA C P C+C T GL+C++C Y
Sbjct: 507 YAVDEITISGRCQCHGHADNC-DTTSQPYR--------CLCSQESFTEGLHCDRCLPLYN 557
Query: 330 DLPWRPAEDGHSHACRKCECHGHTHSCHFDMAV------YLASGNVSGGVCDGCQHNTAG 383
D P+R + ++ C+ C+C+ H+ SCH++++V + G GGVCD C+HNT G
Sbjct: 558 DKPFRQGDQVYAFNCKPCQCNSHSKSCHYNISVDPFPFEHFRGG---GGVCDDCEHNTTG 614
Query: 384 RHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG-RCDSHDDPALGLVSGQCRCKE 442
R+CELC+ +F+R D VC+ CDCD +G+++G CD + GQC CK
Sbjct: 615 RNCELCKDYFFRQVGADPSAIDVCKPCDCDTVGTRNGSILCDQ--------IGGQCNCKR 666
Query: 443 HVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
HV G +C QC++GF+ L D GC C CN GTV G C NSG C CK V G C
Sbjct: 667 HVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRC 726
Query: 503 DRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
D C G L S + +GC PC C++ G+++ C+ +GQC C++ G +C+ + ++
Sbjct: 727 DHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFY 785
Score = 241 bits (615), Expect = 5e-63
Identities = 141/420 (33%), Positives = 188/420 (44%), Gaps = 49/420 (11%)
Query: 782 PCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYYGF---GPTGCQACQCSHE 836
PC C+ G+ + C+ GGQC CK V GR+C+ C G+Y P GC C C+
Sbjct: 640 PCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDGCSPCNCNTS 699
Query: 837 GALSS--LCEKTSGQCLCRTGAFGLRCDRCQRG-----QWGFPSCRPCVCNGHADE---C 886
G + C + SGQC C+ GLRCD C G + C PC CN H C
Sbjct: 700 GTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKFLRSFNDVGCEPCQCNLHGSVNKFC 759
Query: 887 NTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEG---PGSQRHFATSC 943
N H+G C C+ G C+ C F+G C+ C C PG+ + T
Sbjct: 760 NPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT----NCKACDCDTAGSLPGTVCNAKTG- 813
Query: 944 HQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPH 1003
C C+ G +C C G+F C C C C+
Sbjct: 814 ---------QCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 1004 TGQCLRCLHHTEGPHCAHCKPGFHGQAAR--QSCHRCTCNLLGTNPQQCPSPDQCHCDPS 1061
TGQC C G C C+P + Q C C C+ LGT P CDP
Sbjct: 865 TGQC-PCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTI-------CDPI 916
Query: 1062 SGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCR-A 1118
SGQC C+PN QG C++C P F+ ++ G+ GC PC+CH + A CN TGQC C+ A
Sbjct: 917 SGQCLCVPNRQGRRCNQCQPGFY-ISPGNATGCLPCSCHTTGAVNHICNSLTGQCVCQDA 975
Query: 1119 GFGGRTCSECQELHWG-DPGL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176
G+ C +C++ ++G DP +C C+C G CH TG C C+ V+G +CD C
Sbjct: 976 SIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLVTGQCFCKQFVTGSKCDAC 1035
Score = 216 bits (550), Expect = 2e-55
Identities = 123/378 (32%), Positives = 178/378 (47%), Gaps = 32/378 (8%)
Query: 765 CAPLLISLSTLIYNGALPCQCNPQGSLSSE--CNPHGGQCLCKPGVVGRRCDLCAPGYY- 821
C +L L +G PC CN G++ + C+ + GQC CK V+G RCD C G+
Sbjct: 676 CQNGFYNLQELDPDGCSPCNCNTSGTVDGDITCHQNSGQCKCKANVIGLRCDHCNFGFKF 735
Query: 822 --GFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF--PSCRPC 877
F GC+ CQC+ G+++ C SGQC C+ A GL+CD C+ +G +C+ C
Sbjct: 736 LRSFNDVGCEPCQCNLHGSVNKFCNPHSGQCECKKEAKGLQCDTCRENFYGLDVTNCKAC 795
Query: 878 VCNGHAD----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
C+ CN TG C+ C+ + G C +C+ G + R C PC C +
Sbjct: 796 DCDTAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEG-NFYLRQNNSFLCLPCNCDK-- 851
Query: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
+ + C++ C C+ G TGLRC C P + CQ+CEC ++
Sbjct: 852 TGTINGSLLCNKSTGQ----CPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECD-SLG 906
Query: 994 PMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFH-GQAARQSCHRCTCNLLGTNPQQCPS 1052
+ CDP +GQCL C+ + +G C C+PGF+ C C+C+ G C S
Sbjct: 907 TLPGTICDPISGQCL-CVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNS 965
Query: 1053 PDQCHCDPSSGQCPCL-PNVQGPSCDRCAPNFWNLTSGHG-CQPCACHPSRARGPTCNEF 1110
+GQC C ++ G CD+C +++ G CQPC CH S A TC+
Sbjct: 966 --------LTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCHLSGALNETCHLV 1017
Query: 1111 TGQCHCRAGFGGRTCSEC 1128
TGQC C+ G C C
Sbjct: 1018 TGQCFCKQFVTGSKCDAC 1035
Score = 192 bits (487), Expect = 3e-48
Identities = 138/454 (30%), Positives = 193/454 (42%), Gaps = 68/454 (14%)
Query: 782 PCQCNPQGSLSSECNPH--------------GGQCL-CKPGVVGRRCDLCAPGYY---GF 823
PCQCN S S C+ + GG C C+ GR C+LC ++ G
Sbjct: 574 PCQCN---SHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630
Query: 824 GPTG---CQACQCSHEGAL--SSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS----- 873
P+ C+ C C G S LC++ GQC C+ G +C++CQ G +
Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQCNCKRHVSGRQCNQCQNGFYNLQELDPDG 690
Query: 874 CRPCVCN--GHAD---ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCP 928
C PC CN G D C+ ++G C C+ + G C+ C GF G C PC
Sbjct: 691 CSPCNCNTSGTVDGDITCHQNSGQCK-CKANVIGLRCDHCNFGFKFLRSFNDVG-CEPCQ 748
Query: 929 CPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCEC 988
C H + + + +S Q C C+ GL+C+ C +G C+ C+C
Sbjct: 749 C------NLHGSVNKFCNPHSGQ--CECKKEAKGLQCDTCRENFYGLDVT---NCKACDC 797
Query: 989 SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS--CHRCTCNLLGTN 1046
+ C+ TGQC+ C + EG C C G S C C C+ GT
Sbjct: 798 D-TAGSLPGTVCNAKTGQCI-CKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGT- 854
Query: 1047 PQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHP-SRAR 1103
C+ S+GQCPC V G C++C P+ +NLT + CQ C C
Sbjct: 855 -----INGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 1104 GPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPG--LQCHACDCDSRGIDTPQCHRFTGH 1161
G C+ +GQC C GR C++CQ + PG C C C + G C+ TG
Sbjct: 910 GTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQ 969
Query: 1162 CSCRPG-VSGVRCDQCARGFSGIFP---ACHPCH 1191
C C+ ++G RCDQC + G P C PC+
Sbjct: 970 CVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCN 1003
Score = 176 bits (445), Expect = 2e-43
Identities = 141/495 (28%), Positives = 194/495 (39%), Gaps = 92/495 (18%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPG--VVGRRCDLCAPGY-----------YGFGPTGCQ 829
CQC+ + + +CLC G CD C P Y Y F C+
Sbjct: 518 CQCHGHAD-NCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN---CK 573
Query: 830 ACQCSHEGALSSLCEKT--------------SGQCL-CRTGAFGLRCDRCQ----RGQWG 870
CQC+ S C G C C G C+ C+ R
Sbjct: 574 PCQCNSH---SKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFRQVGA 630
Query: 871 FPS----CRPCVCNGHADE-----CNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
PS C+PC C+ C+ G C C+ H G C +C GF+ L
Sbjct: 631 DPSAIDVCKPCDCDTVGTRNGSILCDQIGGQC-NCKRHVSGRQCNQCQNGFYNLQELDPD 689
Query: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
G C PC C +CHQ+ C C+A GLRC+ C G S
Sbjct: 690 G-CSPCNCNTSGTVDGDI--TCHQNSGQ----CKCKANVIGLRCDHCNFGFKFLRSFNDV 742
Query: 982 RCQLCECS--GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039
C+ C+C+ G+++ C+PH+GQC C +G C C+ F+G +C C
Sbjct: 743 GCEPCQCNLHGSVNKF----CNPHSGQC-ECKKEAKGLQCDTCRENFYGLDVT-NCKACD 796
Query: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHG--CQPCAC 1097
C+ G+ P C+ +GQC C PNV+G C++C + L + C PC C
Sbjct: 797 CDTAGSLPGTV-------CNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNC 849
Query: 1098 HPSRARGPT--CNEFTGQCHCRAGFGGRTCSECQELHWG---DPGLQCHACDCDSRG-ID 1151
+ + CN+ TGQC C+ G G C++C+ + D C C+CDS G +
Sbjct: 850 DKTGTINGSLLCNKSTGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 1152 TPQCHRFTGHCSCRPGVSGVRCDQCARGF---SGIFPACHPC---------HACFG-DWD 1198
C +G C C P G RC+QC GF G C PC H C
Sbjct: 910 GTICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTGQ 969
Query: 1199 RVVQDLAARTQRLEQ 1213
V QD + QR +Q
Sbjct: 970 CVCQDASIAGQRCDQ 984
Score = 150 bits (379), Expect = 1e-35
Identities = 87/255 (34%), Positives = 122/255 (47%), Gaps = 30/255 (11%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C CK N GL C+ C ++ L + C C+C+ H F
Sbjct: 713 GQCKCKANVIGLRCDHCNFGFKFL-----RSFNDVGCEPCQCNLHGSVNKFC-------- 759
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
N G C+ C+ G C+ CR FY D C++CDCD GS G C++
Sbjct: 760 NPHSGQCE-CKKEAKGLQCDTCRENFYG------LDVTNCKACDCDTAGSLPGTVCNAK- 811
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
+GQC CK +V G +C +C +G F L ++ C C C+ GT+ GS C+ +
Sbjct: 812 -------TGQCICKPNVEGRQCNKCLEGNFYLRQNNSFLCLPCNCDKTGTINGSLLCNKS 864
Query: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHD-LLGCRPCDCDVGGALDPQ-CDEGTGQCHCRQ 545
+G C CK VTG C++C P + L+ D C+ C+CD G L CD +GQC C
Sbjct: 865 TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLPGTICDPISGQCLCVP 924
Query: 546 HMVGRRCEQVQPGYF 560
+ GRRC Q QPG++
Sbjct: 925 NRQGRRCNQCQPGFY 939
Score = 144 bits (363), Expect = 8e-34
Identities = 84/262 (32%), Positives = 122/262 (46%), Gaps = 44/262 (16%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C CK +GL C+ C++ + L C+ C+C +G
Sbjct: 764 GQCECKKEAKGLQCDTCRENFYGLDVTN--------CKACDCD--------------TAG 801
Query: 368 NVSGGVCDG------CQHNTAGRHCELCRP--FFYRDPTKDLRDPAVCRSCDCDPMGSQD 419
++ G VC+ C+ N GR C C F+ R L C C+CD G+ +
Sbjct: 802 SLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFYLRQNNSFL-----CLPCNCDKTGTIN 856
Query: 420 GGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP 479
G + +GQC CK V G RC QC + L+I + C+ C+C++ GT+P
Sbjct: 857 GSLLCNKS-------TGQCPCKLGVTGLRCNQCEPHRYNLTIDNFQHCQMCECDSLGTLP 909
Query: 480 GSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTG 539
G T CDP SG C C GR C++C PG + + GC PC C GA++ C+ TG
Sbjct: 910 G-TICDPISGQCLCVPNRQGRRCNQCQPGFYISPGNATGCLPCSCHTTGAVNHICNSLTG 968
Query: 540 QCHCRQ-HMVGRRCEQVQPGYF 560
QC C+ + G+RC+Q + YF
Sbjct: 969 QCVCQDASIAGQRCDQCKDHYF 990
Score = 140 bits (352), Expect = 1e-32
Identities = 97/352 (27%), Positives = 152/352 (43%), Gaps = 39/352 (11%)
Query: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRK 346
A +C A P G CICK N G C +C + FY +S C
Sbjct: 794 ACDCDTAGSLPGTVCNAKTGQCICKPNVEGRQCNKCLEGNFY-------LRQNNSFLCLP 846
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
C C T + + + N S G C C+ G C C P Y + +
Sbjct: 847 CNCD-KTGTINGSLLC-----NKSTGQCP-CKLGVTGLRCNQCEPHRYNLTIDNFQH--- 896
Query: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLG 466
C+ C+CD +G+ G CD +SGQC C + G RC QC+ GF+ +S + G
Sbjct: 897 CQMCECDSLGTLPGTICDP--------ISGQCLCVPNRQGRRCNQCQPGFY-ISPGNATG 947
Query: 467 CRRCQCNARGTVPGSTPCDPNSGSCYCKRL-VTGRGCDRCLPGHWGLSHDLLGCRPCDCD 525
C C C+ G V + C+ +G C C+ + G+ CD+C ++G C+PC+C
Sbjct: 948 CLPCSCHTTGAV--NHICNSLTGQCVCQDASIAGQRCDQCKDHYFGFDPQTGRCQPCNCH 1005
Query: 526 VGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFRPFLDHLI------WEAEDTRGQV- 578
+ GAL+ C TGQC C+Q + G +C+ P +++L+ ++ RGQV
Sbjct: 1006 LSGALNETCHLVTGQCFCKQFVTGSKCDACVPSASHLDVNNLLGCSKTPFQQPPPRGQVQ 1065
Query: 579 -LDVVERLVTPGETPSWTGSGFVRLQEGQTLEFLVASVPKAMDYDLLLRLEP 629
+ +P ++P+ + L++G + P ++ Y L L P
Sbjct: 1066 SSSAINLSWSPPDSPNAHWLTYSLLRDGFEIYTTEDQYPYSIQYFLDTDLLP 1117
Score = 39.3 bits (90), Expect = 0.035
Identities = 34/115 (29%), Positives = 45/115 (39%), Gaps = 27/115 (23%)
Query: 469 RCQCNARGTVPGSTPCDPNSGS--CYCKR--LVTGRGCDRCLPGH------WGLSHDLLG 518
RCQC+ + CD S C C + G CDRCLP + G
Sbjct: 517 RCQCHGH-----ADNCDTTSQPYRCLCSQESFTEGLHCDRCLPLYNDKPFRQGDQVYAFN 571
Query: 519 CRPCDCDVGG-------ALDPQCDE----GTGQCH-CRQHMVGRRCEQVQPGYFR 561
C+PC C+ ++DP E G G C C + GR CE + +FR
Sbjct: 572 CKPCQCNSHSKSCHYNISVDPFPFEHFRGGGGVCDDCEHNTTGRNCELCKDYFFR 626
>gi|119466532 laminin alpha 2 subunit isoform b precursor [Homo
sapiens]
Length = 3118
Score = 266 bits (679), Expect = 2e-70
Identities = 134/351 (38%), Positives = 175/351 (49%), Gaps = 22/351 (6%)
Query: 850 CLCRTGAFGLRCDRCQ------RGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGE 903
C C G G C+ C G C PC C GHA+ C+ TG CL C+DHTGG
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 904 HCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGL 963
+C++C+ GF+G+P C+PC CP S +F+ +CH D I C GYTG
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSN-NFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 964 RCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCK 1023
RCE CA G+FG PS PGG CQ C+C+ N+D P +CD +G CL C T G +C C
Sbjct: 843 RCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA 902
Query: 1024 PGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
G+ G A ++C C CN G+ + C S +GQC C NVQG CD+C
Sbjct: 903 DGYFGDAVDAKNCQPCRCNAGGSFSEVCHS--------QTGQCECRANVQGQRCDKCKAG 954
Query: 1083 FWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHA 1142
+ L S GC PC C+ ++ C E +GQC C+ G G+ C C ++ C A
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTA 1013
Query: 1143 CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSG--IFPACHPCH 1191
C+C G C TG C C P G +C +CA G I C C+
Sbjct: 1014 CECSHLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACN 1061
Score = 243 bits (620), Expect = 1e-63
Identities = 148/468 (31%), Positives = 193/468 (41%), Gaps = 95/468 (20%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPT----GCQACQCSHEGALSSLCEKTSGQCL-CRTGA 856
C C PG G C+ C P + T C+ CQC + C+ +G+CL C+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH---AESCDDVTGECLNCKDHT 780
Query: 857 FGLRCDRCQRGQWGFPS------CRPCVC------NGHADECNTHTG---ACLGCRDHTG 901
G CD+C G +G P+ C+PC C N + C+ C GC
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 902 GEHCERCIAGFHGDPRLPYGGQCRPCPCPEG-----PGSQRHFATSCHQDEYSQQIVCHC 956
G CERC G+ G P +P GG C+PC C + PGS + SC C
Sbjct: 841 GPRCERCAEGYFGQPSVP-GGSCQPCQCNDNLDFSIPGSCDSLSGSC----------LIC 889
Query: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
+ G TG CE CA G+FGD + CQ C C N + C TGQC C + +G
Sbjct: 890 KPGTTGRYCELCADGYFGD-AVDAKNCQPCRC--NAGGSFSEVCHSQTGQC-ECRANVQG 945
Query: 1017 PHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQC-------------------- 1056
C CK G G + + C C CN G+ C QC
Sbjct: 946 QRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 1057 ----------------HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPS 1100
+CDP +G+C C PN G C +CAPN W + GC+ C C
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTV 1065
Query: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTP------- 1153
+ CN TGQC+C F G C+EC HW P +C+ CDC G D
Sbjct: 1066 GSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETK 1123
Query: 1154 --QCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHPCHACFG 1195
C TG C+C+ V G+ CD+C G G+ C C+ CFG
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY-CFG 1170
Score = 227 bits (579), Expect = 7e-59
Identities = 151/496 (30%), Positives = 217/496 (43%), Gaps = 60/496 (12%)
Query: 62 LTASSTCGLNGPQPYC-IVSHLQDEK----KCFLCDSRRPFSARDNPHS-HRIQNVVTSF 115
+T ++TCG GP+ YC +V H+ + +C +C+ NP+ H I N +
Sbjct: 52 ITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNS-----SNPNQRHPITNAIDG- 105
Query: 116 APQRRAAWWQS---ENGIPA--VTIQLDLEAEFHFTHLIM-TFKTFRPAAMLVERSADFG 169
+ WWQS +NGI VTI LDL+ F ++I+ + RP ++ERS D
Sbjct: 106 ----KNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDV 161
Query: 170 --RTWHVYRYFSYDCGADFPGVPLAPPRHW---DDVVCESRYSEIEPSTEGEVIYRVLDP 224
+ W + +C + P P + D+V+C S YS+I P GE+ +++
Sbjct: 162 EYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLING 221
Query: 225 AIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLL-----DPRRE---IREKYYYALYE 276
DP S + +R+ R+ TL +L+ DPR + +YYY++ +
Sbjct: 222 RPSADDP-SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKD 280
Query: 277 LVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPA 336
+ V G C CYGHA C P C C+HNT G +C+QC + PWR
Sbjct: 281 ISVGGMCICYGHARACPLDPATNK-------SRCECEHNTCGDSCDQCCPGFHQKPWRAG 333
Query: 337 EDGHSHACRKCECHGHTHSCHFD-------MAVYLASGNVSGGVCDGCQHNTAGRHCELC 389
C C CHG C++D +++ + + GGVC C NTAG +CE C
Sbjct: 334 TFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393
Query: 390 RPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRC 449
F+R P C+ C CDP+GS + GL G C CK G C
Sbjct: 394 TDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC 453
Query: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH 509
+C G+ G C+ C C+ GS DP G C CK V G C RC G
Sbjct: 454 DRCARGYTGYP-----DCKACNCSGL----GSKNEDPCFGPCICKENVEGGDCSRCKSGF 504
Query: 510 WGLSHD-LLGCRPCDC 524
+ L D GC C C
Sbjct: 505 FNLQEDNWKGCDECFC 520
Score = 167 bits (422), Expect = 1e-40
Identities = 95/254 (37%), Positives = 128/254 (50%), Gaps = 23/254 (9%)
Query: 953 VCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
VC C GYTG CE+C P H + + GG C+ C+C G+ ++CD TG+CL C
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH-----AESCDDVTGECLNCK 777
Query: 1012 HHTEGPHCAHCKPGFHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC--P 1066
HT GP+C C PGF+G+ + + C C C L P SP CH D S G
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPL--NIPSNNFSP-TCHLDRSLGLICDG 834
Query: 1067 CLPNVQGPSCDRCAPNFWNLTS--GHGCQPCACHPSR--ARGPTCNEFTGQC-HCRAGFG 1121
C GP C+RCA ++ S G CQPC C+ + + +C+ +G C C+ G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1122 GRTCSECQELHWGD--PGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG 1179
GR C C + ++GD C C C++ G + CH TG C CR V G RCD+C G
Sbjct: 895 GRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAG 954
Query: 1180 FSGIFPA--CHPCH 1191
G+ A C PC+
Sbjct: 955 TFGLQSARGCVPCN 968
Score = 159 bits (402), Expect = 2e-38
Identities = 93/277 (33%), Positives = 127/277 (45%), Gaps = 29/277 (10%)
Query: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF-GPTGCQACQCSHEGALS 840
PC+CN GS S C+ GQC C+ V G+RCD C G +G GC C C+ G+ S
Sbjct: 917 PCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKS 976
Query: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRD 898
CE+ SGQC C+ G G +CDRC G + F C C C+ + C+ TG C+ C
Sbjct: 977 FDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPP 1034
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
+T GE C +C G + G C+ C C + Q C+C
Sbjct: 1035 NTIGEKCSKCAPNTWGHS-ITTG--CKACNCSTVGSLDFQCNVNTGQ--------CNCHP 1083
Query: 959 GYTGLRCEACAPGHFGDPSRPGGRCQLCEC---SGNIDPMDPD----ACDPHTGQCLRCL 1011
++G +C C+ GH+ P RC LC+C + D + +C TGQC C
Sbjct: 1084 KFSGAKCTECSRGHWNYP-----RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CK 1137
Query: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQ 1048
+ EG HC C+PG G A+ +C GT Q
Sbjct: 1138 VNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQ 1174
Score = 150 bits (380), Expect = 8e-36
Identities = 87/254 (34%), Positives = 121/254 (47%), Gaps = 24/254 (9%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
C C G +CE C +R R C C+C GH SC D+
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD-DVT-------- 770
Query: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
G C C+ +T G +C+ C P FY +PTK + C+ C C + H D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNAR--GTVPGSTPCDPN 487
+LGL+ C G RC++C +G+FG C+ CQCN ++PGS CD
Sbjct: 827 SLGLICDGCPVG--YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS--CDSL 882
Query: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQH 546
SGSC CK TGR C+ C G++G + D C+PC C+ GG+ C TGQC CR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 547 MVGRRCEQVQPGYF 560
+ G+RC++ + G F
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 135 bits (341), Expect = 3e-31
Identities = 98/370 (26%), Positives = 134/370 (36%), Gaps = 120/370 (32%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
C C+GHA C V G C+ CK +T G C++C + P + G S
Sbjct: 757 CQCFGHAESCDD-----------VTGECLNCKDHTGGPYCDKCLPGFYGEPTK----GTS 801
Query: 342 HACRKCEC------HGHTHSCHFDMAV----------------------YLASGNVSGGV 373
C+ C C + + +CH D ++ Y +V GG
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS 861
Query: 374 CDGCQHN------------------------TAGRHCELCRPFFYRDPTKDLRDPAVCRS 409
C CQ N T GR+CELC ++ D D C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV----DAKNCQP 917
Query: 410 CDCDPMGS-----------------QDGGRCDSHDDPALGLVS----------------- 435
C C+ GS G RCD GL S
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 436 -----GQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS 490
GQC C+ V G +C +C G+F GC C+C+ G CDP +G
Sbjct: 978 DCEESGQCWCQPGVTGKKCDRCAHGYFNFQEG---GCTACECSHLGN-----NCDPKTGR 1029
Query: 491 CYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGR 550
C C G C +C P WG S GC+ C+C G+LD QC+ TGQC+C G
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 551 RCEQVQPGYF 560
+C + G++
Sbjct: 1089 KCTECSRGHW 1098
Score = 133 bits (334), Expect = 2e-30
Identities = 181/827 (21%), Positives = 314/827 (37%), Gaps = 101/827 (12%)
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGR--------CQLCECSGNIDPMDPDACDPHTG 1005
C C GY+GL CEAC PG + S+PGGR C C+C+G+ CDP T
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SSLCDPETS 1434
Query: 1006 QCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDP-SS 1062
C C HHT G C C G++G + C +C C L+ ++ PS C +
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPS---CVAEGLDD 1491
Query: 1063 GQCPCLP-NVQGPSCDRCAPNFWNL--TSGHGCQPCACHPSRARGPTCNEFTGQCHCRAG 1119
+C P +G C+RCAP + G CQ C C P + C+ TG C CR G
Sbjct: 1492 YRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPG 1551
Query: 1120 FGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG 1179
GR C C+ H G +C C + G+ G + R +Q
Sbjct: 1552 ATGRKCDGCKHWH-AREGWECVFCGDECTGL-------LLGDLA--------RLEQMVMS 1595
Query: 1180 FSGIFPACHPCHACFGDWDRVVQDL--AARTQRLEQRAQELQQTGVLGAFESSFWHMQEK 1237
+ P P +G + + Q+L QR +R +L + G + M E
Sbjct: 1596 INLTGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAE----GNLNTLVTEMNEL 1650
Query: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297
L + T Q E T + +G E + +L D V ++ N L
Sbjct: 1651 LTRATKV----TADGEQTGQDAERTNTRAKSLG---EFIKELARDAEAVNEKAIKLNETL 1703
Query: 1298 SGLERDRLALNL--TLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVP 1355
G + NL +++DQ + L+ N L I +AEA + L
Sbjct: 1704 -GTRDEAFERNLEGLQKEIDQMIKELRRKN-LETQKEIAEDELVAAEALLK-KVKKLFGE 1760
Query: 1356 SPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGD 1415
S N + E L D + + ++ + + A K+ ++ N +
Sbjct: 1761 SRGENEEMEKDLREKLADYKNKVDDAWDLLRE-ATDKIREANRLFAVNQKNMTALEKKKE 1819
Query: 1416 APCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILS 1475
A +G R + + G + A AD + + ++Q L L+
Sbjct: 1820 AV-------ESGKRQIENTLKEGNDILDEANRLADEINSIIDYVE-DIQTKLPPMSEELN 1871
Query: 1476 RVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEM 1535
+ Q + ++ A+ + +A + Q+ ++ L ++ K+ A +
Sbjct: 1872 DKIDDLSQEIKDRKLAE-KVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSN 1930
Query: 1536 VATRVLEL-SIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRAR 1594
+ + E + A+ + H A +A R L DA G ++++ ++L +A++
Sbjct: 1931 IKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA-----KGCLQKSFRILNEAKKLA 1985
Query: 1595 SWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAV----ADTRDTEQTLYQVQERMAGAE 1650
+ ++ + ++ +E A G + + A DT L V+++ A
Sbjct: 1986 NDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK---AR 2042
Query: 1651 RALSSAGERARQLDALLEALK-LKRAGNSLAASTAEETA---------------GSAQGR 1694
+A +A + Q+ L + L LK+ N LA S A+ A + +
Sbjct: 2043 QANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNL 2102
Query: 1695 AQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDL 1741
QEA++L+ D+ + +K L + + + + Q R +A +
Sbjct: 2103 EQEADRLI-----DKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Score = 129 bits (324), Expect = 3e-29
Identities = 73/191 (38%), Positives = 88/191 (46%), Gaps = 24/191 (12%)
Query: 849 QCLCRTGAFGLRCDRCQRGQWGFPS-------------CRPCVCNGHADECNTHTGACLG 895
+C C G GL C+ C G + S C PC CNGH+ C+ T C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 896 CRDHTGGEHCERCIAGFHGDPR-LPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC 954
C+ HT G+ CERC G++G + LP C+ C CP S +F+ SC +
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLP--NDCQQCACPL-ISSSNNFSPSCVAEGLDDYRCT 1495
Query: 955 HCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMD--PDACDPHTGQCLRCLH 1012
C GY G CE CAPG+ G P PGG CQ CEC DP P CDP TG C C
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRP 1550
Query: 1013 HTEGPHCAHCK 1023
G C CK
Sbjct: 1551 GATGRKCDGCK 1561
Score = 114 bits (286), Expect = 7e-25
Identities = 82/292 (28%), Positives = 119/292 (40%), Gaps = 44/292 (15%)
Query: 299 PAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHG---HTHS 355
P + + ICK T G CE C D Y + A D + C+ C C+ +
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELCADGY----FGDAVDAKN--CQPCRCNAGGSFSEV 929
Query: 356 CHFDMAVYLASGNVSGGVCDGCQHNTAG----RHCELCRPFFYRDPTKDLRDPAVC---- 407
CH NV G CD C+ T G R C C + + D + C
Sbjct: 930 CHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQP 989
Query: 408 ----RSCDCDPMGS---QDGG--RCD-SHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF 457
+ CD G Q+GG C+ SH +G+C C + +G +C +C +
Sbjct: 990 GVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTW 1049
Query: 458 GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517
G SI+ GC+ C C+ G++ C+ N+G C C +G C C GHW
Sbjct: 1050 GHSITT--GCKACNCSTVGSL--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--- 1102
Query: 518 GCRPCDCDVGGALDPQCD---------EGTGQCHCRQHMVGRRCEQVQPGYF 560
C CDC + G CD + TGQC C+ ++ G C++ +PG F
Sbjct: 1103 -CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKF 1153
Score = 98.2 bits (243), Expect = 6e-20
Identities = 66/205 (32%), Positives = 90/205 (43%), Gaps = 25/205 (12%)
Query: 310 CICKHNTRGLNCEQC-QDFYR--DLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLAS 366
C C GL+CE C FYR P C C+C+GH+ C + ++
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI---- 1435
Query: 367 GNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSH 426
C CQH+TAG CE C +Y K L P C+ C C + S + S
Sbjct: 1436 -------CQNCQHHTAGDFCERCALGYY-GIVKGL--PNDCQQCACPLISSSNNF---SP 1482
Query: 427 DDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCD 485
A GL +C C G C++C G+ G + C+ C+C+ G++P PCD
Sbjct: 1483 SCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD 1540
Query: 486 PNSGSCYCKRLVTGRGCDRCLPGHW 510
P +G C C+ TGR CD C HW
Sbjct: 1541 PVTGFCTCRPGATGRKCDGC--KHW 1563
Score = 95.9 bits (237), Expect = 3e-19
Identities = 70/248 (28%), Positives = 94/248 (37%), Gaps = 57/248 (22%)
Query: 849 QCLCRTGAFGLRCDRCQRGQWGFP----------SCRPCVCNGHADECNTHT-------- 890
+C C G CD+C G P C C C+G A+EC
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 891 ----------GACLGCRDHTGGEHCERCIAGFHGDPRLP--YGGQCRPCPC-PEGPGSQR 937
G C+ C +T G +CE C GF + Y C+PC C P G ++
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDP 997
H CHC+ G+ G+ C+ CA G+ G P C+ C CSG +
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSG----LGS 476
Query: 998 DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH 1057
DP G C+ C + EG C+ CK GF NL N + C D+C
Sbjct: 477 KNEDPCFGPCI-CKENVEGGDCSRCKSGFF-------------NLQEDNWKGC---DECF 519
Query: 1058 CDPSSGQC 1065
C S +C
Sbjct: 520 CSGVSNRC 527
Score = 94.0 bits (232), Expect = 1e-18
Identities = 65/237 (27%), Positives = 102/237 (43%), Gaps = 41/237 (17%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK--DLRDP 404
C C+GH +C D A + C+ C+HNT G C+ C P F++ P +
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVS----------GQC-RCKEHVVGTRCQQCR 453
C +C+C + C ++ A +S G C C ++ G C+ C
Sbjct: 339 TECEACNCHGKAEE----CYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCT 394
Query: 454 DGFF---GLSISDRLGCRRCQCNARGTVPGSTPCDPNS-------GSCYCKRLVTGRGCD 503
DGFF G+S + C+ C C+ G++ D GSC+CK G CD
Sbjct: 395 DGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD 454
Query: 504 RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
RC G+ G C+ C+C G+ + D G C C++++ G C + + G+F
Sbjct: 455 RCARGYTGYPD----CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFF 505
Score = 93.2 bits (230), Expect = 2e-18
Identities = 77/257 (29%), Positives = 97/257 (37%), Gaps = 59/257 (22%)
Query: 877 CVCNGHADECN----THTGACLGCRDHTGGEHCERCIAGFHGDP----RLPYGGQCRPCP 928
C+C GHA C T+ C C +T G+ C++C GFH P +C C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 929 CPEGPGSQRHFATSCHQDEYSQQI--------VC-HCRAGYTGLRCEACAPGHFGDPSRP 979
C G + ++ + + S I VC +C G+ CE C G F RP
Sbjct: 346 C-HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF----RP 400
Query: 980 GG-------RCQLCECSGNIDPMDP--DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA 1030
G CQ C C DP+ + C R L P HCK GF G
Sbjct: 401 KGVSPNYPRPCQPCHC----DPIGSLNEVCVKDEKHARRGL----APGSCHCKTGFGGV- 451
Query: 1031 ARQSCHRCTCNLLGTNPQQCPSPDQCHC--------DPSSGQCPCLPNVQGPSCDRCAPN 1082
SC RC G P C+C DP G C C NV+G C RC
Sbjct: 452 ---SCDRCARGYTGY-----PDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSG 503
Query: 1083 FWNLTSGH--GCQPCAC 1097
F+NL + GC C C
Sbjct: 504 FFNLQEDNWKGCDECFC 520
Score = 90.5 bits (223), Expect = 1e-17
Identities = 67/253 (26%), Positives = 93/253 (36%), Gaps = 60/253 (23%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS----- 1034
GG C +C P+DP + +C C H+T G C C PGFH + R
Sbjct: 284 GGMC-ICYGHARACPLDPAT---NKSRC-ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 1035 --CHRCTCNLLGTNPQQCPSPDQCHCDPS----------------SGQC-PCLPNVQGPS 1075
C C C+ ++C+ D + G C C N G +
Sbjct: 339 TECEACNCH---------GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 1076 CDRCAPNFWNLTS-----GHGCQPCACHPSRARGPTCNE---------FTGQCHCRAGFG 1121
C+ C F+ CQPC C P + C + G CHC+ GFG
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 1122 GRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFS 1181
G +C C + G P C AC+C G+ + G C C+ V G C +C GF
Sbjct: 450 GVSCDRCARGYTGYP--DCKACNCS--GLGSKNEDPCFGPCICKENVEGGDCSRCKSGFF 505
Query: 1182 GI----FPACHPC 1190
+ + C C
Sbjct: 506 NLQEDNWKGCDEC 518
Score = 90.1 bits (222), Expect = 2e-17
Identities = 69/219 (31%), Positives = 89/219 (40%), Gaps = 46/219 (21%)
Query: 801 QCLCKPGVVGRRCDLCAPGYYGF---------GPT--GCQACQCSHEGALSSLCEKTSGQ 849
+C C G G C+ C PG+Y GPT C CQC+ SSLC+ +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH---SSLCDPETSI 1435
Query: 850 CL-CRTGAFGLRCDRCQRGQWGF-----PSCRPCVC------NGHADEC---NTHTGACL 894
C C+ G C+RC G +G C+ C C N + C C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 895 GCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIV 953
C G++CERC G+ G P P GG C+ C C P G C D +
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNP-GGSCQECECDPYG-----SLPVPC--DPVTG--F 1545
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLC--ECSG 990
C CR G TG +C+ C H +R G C C EC+G
Sbjct: 1546 CTCRPGATGRKCDGCKHWH----AREGWECVFCGDECTG 1580
Score = 88.2 bits (217), Expect = 7e-17
Identities = 51/151 (33%), Positives = 70/151 (46%), Gaps = 25/151 (16%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYY---GFGPT---GCQACQCSHEGALSSLCEKTS---- 847
GG C+ C G C+ C G++ G P CQ C C G+L+ +C K
Sbjct: 375 GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 848 -----GQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNG----HADECNTHTGACLGCRD 898
G C C+TG G+ CDRC RG G+P C+ C C+G + D C G C+ C++
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPC---FGPCI-CKE 490
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPC 929
+ G C RC +GF + G C C C
Sbjct: 491 NVEGGDCSRCKSGFFNLQEDNWKG-CDECFC 520
Score = 85.9 bits (211), Expect = 3e-16
Identities = 68/242 (28%), Positives = 94/242 (38%), Gaps = 54/242 (22%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C C+ G C++C Y + ++G C CEC ++C
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGYFNF-----QEG---GCTACECSHLGNNC----------- 1023
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
+ G C C NT G C C P + C++C+C +GS D +C+ +
Sbjct: 1024 DPKTGRCI-CPPNTIGEKCSKCAPNTWGHSIT-----TGCKACNCSTVGSLDF-QCNVN- 1075
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
+GQC C G +C +C G + C C C GT +T CD
Sbjct: 1076 -------TGQCNCHPKFSGAKCTECSRGHWNYP-----RCNLCDCFLPGT--DATTCDSE 1121
Query: 488 S---------GSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEG 537
+ G C CK V G CDRC PG +GL + + LGC C C QC E
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCSEA 1178
Query: 538 TG 539
G
Sbjct: 1179 KG 1180
Score = 84.3 bits (207), Expect = 9e-16
Identities = 58/191 (30%), Positives = 81/191 (42%), Gaps = 23/191 (12%)
Query: 374 CDGCQHNTAGRHCELCRPFFYR---DPTKDLRDPAV--CRSCDCDPMGSQDGGRCDSHDD 428
CD C +G CE C P FYR P P + C C C+ S CD
Sbjct: 1380 CD-CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CD---- 1430
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
P + C+ H G C++C G++G+ C++C C + +P
Sbjct: 1431 PETSICQN---CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE 1487
Query: 489 G-----SCYCKRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQCH 542
G C R G+ C+RC PG+ G + G C+ C+CD G+L CD TG C
Sbjct: 1488 GLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCT 1547
Query: 543 CRQHMVGRRCE 553
CR GR+C+
Sbjct: 1548 CRPGATGRKCD 1558
Score = 77.0 bits (188), Expect = 2e-13
Identities = 172/798 (21%), Positives = 274/798 (34%), Gaps = 149/798 (18%)
Query: 1064 QCPCLPNVQGPSCDRCAPNFWNLTSGHG----------CQPCACH--------------- 1098
+C C G SC+ C P F+ L S G C PC C+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1099 ------------------------PSRARGPTC------NEFTGQC-----------HCR 1117
P+ + C N F+ C C
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1118 AGFGGRTCSECQELHW---GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD 1174
G+ G+ C C + G+PG C C+CD G C TG C+CRPG +G +CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1175 QCARGFSGIFPACHPC-HACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWH 1233
C + C C C G ++ DLA RLEQ + TG L A +
Sbjct: 1559 GCKHWHAREGWECVFCGDECTG---LLLGDLA----RLEQMVMSINLTGPLPAPYKMLYG 1611
Query: 1234 MQEKLGIVQGIVGARNTSAASTAQLVEAT-EELRREIGEATEHLTQLEAD----LTDVQD 1288
++ ++ ++ + + QL E L E+ E T++ AD D +
Sbjct: 1612 LENMTQELKHLLSPQR-APERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAER 1670
Query: 1289 ENFNA---NHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAER 1345
N A + L RD A+N +L++ L + F + ++ Q + R
Sbjct: 1671 TNTRAKSLGEFIKELARDAEAVNEKAIKLNETLG-TRDEAFERNLEGLQKEIDQMIKELR 1729
Query: 1346 RANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDI 1405
R N L ++ EAL+ K+ F N+ L L D
Sbjct: 1730 RKN---LETQKEIAEDELV--AAEALLKKVKKLFGESRGENEEMEKDLRE-----KLADY 1779
Query: 1406 NELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQR 1465
V A AT A Q L A + + +++
Sbjct: 1780 KNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESG---------KRQIEN 1830
Query: 1466 ALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ 1525
L EG IL E R A E D E+ N ++ +L Q +KD
Sbjct: 1831 TLKEGNDILD---EANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLA 1887
Query: 1526 E---GADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRR 1582
E A+ + ++ + + I A+ I A A + ++ D +
Sbjct: 1888 EKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDY----------IDE 1937
Query: 1583 AEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIR------GAVADTRDTE 1636
AE++ A+ A+ A + + A + L+E A+G Q + R D ++ E
Sbjct: 1938 AEKV---AKEAKDLAHEATKLATGPRGLLKE--DAKGCLQKSFRILNEAKKLANDVKENE 1992
Query: 1637 QTLYQVQERMAGAER----ALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQ 1692
L ++ R+ A+ L + + +L A+ K A A +TA
Sbjct: 1993 DHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVL 2052
Query: 1693 GRAQEAEQLLRG------PLGDQYQTVKALAERKAQGVLAAQARA--EQLRDEARDLLQA 1744
+ E Q L G L D A+ + ++ + A A A + L EA L+
Sbjct: 2053 AQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLI-- 2110
Query: 1745 AQDKLQRLQELEGTYEEN 1762
DKL+ ++ELE ++N
Sbjct: 2111 --DKLKPIKELEDNLKKN 2126
Score = 75.9 bits (185), Expect = 3e-13
Identities = 66/231 (28%), Positives = 95/231 (41%), Gaps = 41/231 (17%)
Query: 355 SCHFDMAV-YLASGNVSGGV--CDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCD 411
S + + AV Y G+++ V C C G CE C P R +C C
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQ-CPPGYTGSSCESCWPRHRR--VNGTIFGGICEPCQ 758
Query: 412 CDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRL-GCRR 469
C G +S DD V+G+C CK+H G C +C GF+G C+
Sbjct: 759 CF-------GHAESCDD-----VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP 806
Query: 470 CQCNARGTVPGSTPCDPNSGSCYCKRLV-----------TGRGCDRCLPGHWGLSHDLLG 518
C C P + P + S +C+ R + TG C+RC G++G G
Sbjct: 807 CAC------PLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 519 -CRPCDCD--VGGALDPQCDEGTGQCH-CRQHMVGRRCEQVQPGYFRPFLD 565
C+PC C+ + ++ CD +G C C+ GR CE GYF +D
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVD 911
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/151 (33%), Positives = 61/151 (40%), Gaps = 31/151 (20%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYGFG---PTGCQACQCSHE 836
+PCQCN SL C+P C C+ G C+ CA GYYG P CQ C C
Sbjct: 1418 VPCQCNGHSSL---CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC--- 1471
Query: 837 GALSSLCEKTSGQCL-----------CRTGAFGLRCDRCQRGQWGFP-----SCRPCVCN 880
L S S C+ C G G C+RC G G P SC+ C C+
Sbjct: 1472 -PLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Query: 881 GHAD---ECNTHTGACLGCRDHTGGEHCERC 908
+ C+ TG C CR G C+ C
Sbjct: 1531 PYGSLPVPCDPVTGFCT-CRPGATGRKCDGC 1560
Score = 69.3 bits (168), Expect = 3e-11
Identities = 53/146 (36%), Positives = 65/146 (44%), Gaps = 21/146 (14%)
Query: 753 GLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRR 812
G+V + + CA LIS S N P C +G C C G G+
Sbjct: 1457 GIVKGLPNDCQQCACPLISSS----NNFSP-SCVAEGLDDYRCTA------CPRGYEGQY 1505
Query: 813 CDLCAPGYYGF--GPTG-CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQW 869
C+ CAPGY G P G CQ C+C G+L C+ +G C CR GA G +CD C+ W
Sbjct: 1506 CERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCK--HW 1563
Query: 870 GFPSCRPCVCNGHADECNTHTGACLG 895
CV G DEC TG LG
Sbjct: 1564 HAREGWECVFCG--DEC---TGLLLG 1584
Score = 67.8 bits (164), Expect = 9e-11
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 42/180 (23%)
Query: 1056 CHCDPSSGQ--CPCLPNVQGPSCDRCAPNFWNLTSGHG-------CQPCACHPSR----- 1101
C DP++ + C C N G SCD+C P F G C+ C CH
Sbjct: 296 CPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYY 355
Query: 1102 ----ARGPTCNEFTGQ-------CHCRAGFGGRTCSECQELHWGDPGLQ------CHACD 1144
AR G+ +C G C C + + G+ C C
Sbjct: 356 DENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCH 415
Query: 1145 CDSRGIDTPQCHRFTGH---------CSCRPGVSGVRCDQCARGFSGIFPACHPCHACFG 1195
CD G C + H C C+ G GV CD+CARG++G +P C C+ C G
Sbjct: 416 CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG-YPDCKACN-CSG 473
Score = 65.9 bits (159), Expect = 3e-10
Identities = 63/259 (24%), Positives = 87/259 (33%), Gaps = 67/259 (25%)
Query: 775 LIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYG--------FGPT 826
+ Y A C +P + S +C C+ G CD C PG++ T
Sbjct: 288 ICYGHARACPLDPATNKS--------RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKT 339
Query: 827 GCQACQCSHEGALSSLCEKTS---------------GQCL-CRTGAFGLRCDRCQRGQW- 869
C+AC C + E + G C+ C G+ C+ C G +
Sbjct: 340 ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFR 399
Query: 870 ------GFP-SCRPCVCNGHA--------DECNTHTGACLG---CRDHTGGEHCERCIAG 911
+P C+PC C+ DE + G G C+ GG C+RC G
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG 459
Query: 912 FHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG 971
+ G P C+ C C G GS+ C C C+ G C C G
Sbjct: 460 YTGYP------DCKACNC-SGLGSKNE--DPCFGP-------CICKENVEGGDCSRCKSG 503
Query: 972 HFGDPSRPGGRCQLCECSG 990
F C C CSG
Sbjct: 504 FFNLQEDNWKGCDECFCSG 522
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/171 (27%), Positives = 70/171 (40%), Gaps = 29/171 (16%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C GH+S C P + C+H+T G CE+C L + G +
Sbjct: 1420 CQCNGHSSLCDPETSICQN----------CQHHTAGDFCERCA-----LGYYGIVKGLPN 1464
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
C++C C + S +F + +A G + C C G++CE C P + P
Sbjct: 1465 DCQQCACPLISSSNNFSPSC-VAEG-LDDYRCTACPRGYEGQYCERCAPGYTGSPG---N 1519
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
C+ C+CDP GS CD V+G C C+ G +C C+
Sbjct: 1520 PGGSCQECECDPYGSLP-VPCDP--------VTGFCTCRPGATGRKCDGCK 1561
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 22/140 (15%)
Query: 437 QCRCKEHVVGTRCQQCRDGFF-------GLSISDRLG-CRRCQCNARGTVPGSTPCDPNS 488
+C C G C+ C GF+ G + LG C CQCN S+ CDP +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SSLCDPET 1433
Query: 489 GSCY-CKRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDV---GGALDPQC-DEGTGQCH 542
C C+ G C+RC G++G+ L C+ C C + P C EG
Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 543 CR---QHMVGRRCEQVQPGY 559
C + G+ CE+ PGY
Sbjct: 1494 CTACPRGYEGQYCERCAPGY 1513
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/96 (32%), Positives = 40/96 (41%), Gaps = 15/96 (15%)
Query: 475 RGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG---------CRPCDCD 525
RGT TP C C +G C+ CLPG + L G C PC C+
Sbjct: 1366 RGTT--MTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN 1423
Query: 526 VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
+L CD T C +C+ H G CE+ GY+
Sbjct: 1424 GHSSL---CDPETSICQNCQHHTAGDFCERCALGYY 1456
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 26/105 (24%)
Query: 483 PCDP--NSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPCDCDVGGALDPQC 534
P DP N C C+ G CD+C PG W G C C+C G A +
Sbjct: 297 PLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCH-GKAEECYY 355
Query: 535 DE----------------GTGQC-HCRQHMVGRRCEQVQPGYFRP 562
DE G G C +C Q+ G CE G+FRP
Sbjct: 356 DENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 777 YNGALPCQ-CNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP---TGCQACQ 832
Y G C+ CN G S +P G C+CK V G C C G++ GC C
Sbjct: 460 YTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECF 519
Query: 833 CSHEGALSSLCEKT 846
CS +S+ C+ +
Sbjct: 520 CS---GVSNRCQSS 530
Score = 39.3 bits (90), Expect = 0.035
Identities = 47/223 (21%), Positives = 98/223 (43%), Gaps = 30/223 (13%)
Query: 1566 LADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAI 1625
+ +++ +L R EQ QDA R + A K E ++ E A+ A+ + + AI
Sbjct: 1644 VTEMNELLTRATKVTADGEQTGQDAERTNTRA---KSLGEFIK---ELARDAEAVNEKAI 1697
Query: 1626 RGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAE 1685
+ + +T T ++ + G ++ ++D +++ +L+R AE
Sbjct: 1698 K--LNETLGTRDEAFE--RNLEGLQK----------EIDQMIK--ELRRKNLETQKEIAE 1741
Query: 1686 ETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAA 1745
+ +A+ ++ ++L G+ + K L E+ A + D+A DLL+ A
Sbjct: 1742 DELVAAEALLKKVKKLFGESRGENEEMEKDLREKLAD--------YKNKVDDAWDLLREA 1793
Query: 1746 QDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAIN 1788
DK++ L ++N ALE K ++ + ++ + L+ N
Sbjct: 1794 TDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGN 1836
Score = 36.6 bits (83), Expect = 0.23
Identities = 69/363 (19%), Positives = 137/363 (37%), Gaps = 56/363 (15%)
Query: 1440 LSCNGAAATADLALGR-ARHTQAELQRALAEGGSILSRVAETRRQASEAQQ-RAQAALDK 1497
+ N T D A R Q E+ + + E + + ET+++ +E + A+A L K
Sbjct: 1697 IKLNETLGTRDEAFERNLEGLQKEIDQMIKE---LRRKNLETQKEIAEDELVAAEALLKK 1753
Query: 1498 ANASRGQVEQANQELQ-ELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLA 1556
G+ N+E++ +L + + D+ N+ D + ++ E + + Q A
Sbjct: 1754 VKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTA 1813
Query: 1557 GAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQR 1616
E+ + V++ + ++ +L +A R E +Q L
Sbjct: 1814 ---LEKKKEA--VESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSE 1868
Query: 1617 AQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAG 1676
+ + D + + E+++ AE + + + LD +L+ K +
Sbjct: 1869 ELNDKIDDLSQEIKDRK--------LAEKVSQAESHAAQLNDSSAVLDGILDEAK-NISF 1919
Query: 1677 NSLAA-----------STAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVL 1725
N+ AA AE+ A A+ A EA +L GP G
Sbjct: 1920 NATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRG------------------ 1961
Query: 1726 AAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQ 1785
L+++A+ LQ + L ++L +ENE L +++ +AR +L+
Sbjct: 1962 -------LLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLR 2014
Query: 1786 AIN 1788
+N
Sbjct: 2015 TLN 2017
>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
sapiens]
Length = 3122
Score = 266 bits (679), Expect = 2e-70
Identities = 134/351 (38%), Positives = 175/351 (49%), Gaps = 22/351 (6%)
Query: 850 CLCRTGAFGLRCDRCQ------RGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGE 903
C C G G C+ C G C PC C GHA+ C+ TG CL C+DHTGG
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGHAESCDDVTGECLNCKDHTGGP 783
Query: 904 HCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGL 963
+C++C+ GF+G+P C+PC CP S +F+ +CH D I C GYTG
Sbjct: 784 YCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSN-NFSPTCHLDRSLGLICDGCPVGYTGP 842
Query: 964 RCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCK 1023
RCE CA G+FG PS PGG CQ C+C+ N+D P +CD +G CL C T G +C C
Sbjct: 843 RCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCA 902
Query: 1024 PGFHGQAA-RQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
G+ G A ++C C CN G+ + C S +GQC C NVQG CD+C
Sbjct: 903 DGYFGDAVDAKNCQPCRCNAGGSFSEVCHS--------QTGQCECRANVQGQRCDKCKAG 954
Query: 1083 FWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHA 1142
+ L S GC PC C+ ++ C E +GQC C+ G G+ C C ++ C A
Sbjct: 955 TFGLQSARGCVPCNCNSFGSKSFDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTA 1013
Query: 1143 CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSG--IFPACHPCH 1191
C+C G C TG C C P G +C +CA G I C C+
Sbjct: 1014 CECSHLG---NNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACN 1061
Score = 243 bits (620), Expect = 1e-63
Identities = 148/468 (31%), Positives = 193/468 (41%), Gaps = 95/468 (20%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPT----GCQACQCSHEGALSSLCEKTSGQCL-CRTGA 856
C C PG G C+ C P + T C+ CQC + C+ +G+CL C+
Sbjct: 724 CQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH---AESCDDVTGECLNCKDHT 780
Query: 857 FGLRCDRCQRGQWGFPS------CRPCVC------NGHADECNTHTG---ACLGCRDHTG 901
G CD+C G +G P+ C+PC C N + C+ C GC
Sbjct: 781 GGPYCDKCLPGFYGEPTKGTSEDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYT 840
Query: 902 GEHCERCIAGFHGDPRLPYGGQCRPCPCPEG-----PGSQRHFATSCHQDEYSQQIVCHC 956
G CERC G+ G P +P GG C+PC C + PGS + SC C
Sbjct: 841 GPRCERCAEGYFGQPSVP-GGSCQPCQCNDNLDFSIPGSCDSLSGSC----------LIC 889
Query: 957 RAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEG 1016
+ G TG CE CA G+FGD + CQ C C N + C TGQC C + +G
Sbjct: 890 KPGTTGRYCELCADGYFGD-AVDAKNCQPCRC--NAGGSFSEVCHSQTGQC-ECRANVQG 945
Query: 1017 PHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQC-------------------- 1056
C CK G G + + C C CN G+ C QC
Sbjct: 946 QRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQPGVTGKKCDRCAHGYFN 1005
Query: 1057 ----------------HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPS 1100
+CDP +G+C C PN G C +CAPN W + GC+ C C
Sbjct: 1006 FQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTWGHSITTGCKACNCSTV 1065
Query: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTP------- 1153
+ CN TGQC+C F G C+EC HW P +C+ CDC G D
Sbjct: 1066 GSLDFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYP--RCNLCDCFLPGTDATTCDSETK 1123
Query: 1154 --QCHRFTGHCSCRPGVSGVRCDQCARGFSGIFP----ACHPCHACFG 1195
C TG C+C+ V G+ CD+C G G+ C C+ CFG
Sbjct: 1124 KCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCY-CFG 1170
Score = 227 bits (579), Expect = 7e-59
Identities = 151/496 (30%), Positives = 217/496 (43%), Gaps = 60/496 (12%)
Query: 62 LTASSTCGLNGPQPYC-IVSHLQDEK----KCFLCDSRRPFSARDNPHS-HRIQNVVTSF 115
+T ++TCG GP+ YC +V H+ + +C +C+ NP+ H I N +
Sbjct: 52 ITTNATCGEKGPEMYCKLVEHVPGQPVRNPQCRICNQNS-----SNPNQRHPITNAIDG- 105
Query: 116 APQRRAAWWQS---ENGIPA--VTIQLDLEAEFHFTHLIM-TFKTFRPAAMLVERSADFG 169
+ WWQS +NGI VTI LDL+ F ++I+ + RP ++ERS D
Sbjct: 106 ----KNTWWQSPSIKNGIEYHYVTITLDLQQVFQIAYVIVKAANSPRPGNWILERSLDDV 161
Query: 170 --RTWHVYRYFSYDCGADFPGVPLAPPRHW---DDVVCESRYSEIEPSTEGEVIYRVLDP 224
+ W + +C + P P + D+V+C S YS+I P GE+ +++
Sbjct: 162 EYKPWQYHAVTDTECLTLYNIYPRTGPPSYAKDDEVICTSFYSKIHPLENGEIHISLING 221
Query: 225 AIPIPDPYSSRIQNLLKITNLRVNLTRLHTLGDNLL-----DPRRE---IREKYYYALYE 276
DP S + +R+ R+ TL +L+ DPR + +YYY++ +
Sbjct: 222 RPSADDP-SPELLEFTSARYIRLRFQRIRTLNADLMMFAHKDPREIDPIVTRRYYYSVKD 280
Query: 277 LVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPA 336
+ V G C CYGHA C P C C+HNT G +C+QC + PWR
Sbjct: 281 ISVGGMCICYGHARACPLDPATNK-------SRCECEHNTCGDSCDQCCPGFHQKPWRAG 333
Query: 337 EDGHSHACRKCECHGHTHSCHFD-------MAVYLASGNVSGGVCDGCQHNTAGRHCELC 389
C C CHG C++D +++ + + GGVC C NTAG +CE C
Sbjct: 334 TFLTKTECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETC 393
Query: 390 RPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRC 449
F+R P C+ C CDP+GS + GL G C CK G C
Sbjct: 394 TDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSC 453
Query: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH 509
+C G+ G C+ C C+ GS DP G C CK V G C RC G
Sbjct: 454 DRCARGYTGYP-----DCKACNCSGL----GSKNEDPCFGPCICKENVEGGDCSRCKSGF 504
Query: 510 WGLSHD-LLGCRPCDC 524
+ L D GC C C
Sbjct: 505 FNLQEDNWKGCDECFC 520
Score = 167 bits (422), Expect = 1e-40
Identities = 95/254 (37%), Positives = 128/254 (50%), Gaps = 23/254 (9%)
Query: 953 VCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
VC C GYTG CE+C P H + + GG C+ C+C G+ ++CD TG+CL C
Sbjct: 723 VCQCPPGYTGSSCESCWPRHRRVNGTIFGGICEPCQCFGH-----AESCDDVTGECLNCK 777
Query: 1012 HHTEGPHCAHCKPGFHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC--P 1066
HT GP+C C PGF+G+ + + C C C L P SP CH D S G
Sbjct: 778 DHTGGPYCDKCLPGFYGEPTKGTSEDCQPCACPL--NIPSNNFSP-TCHLDRSLGLICDG 834
Query: 1067 CLPNVQGPSCDRCAPNFWNLTS--GHGCQPCACHPSR--ARGPTCNEFTGQC-HCRAGFG 1121
C GP C+RCA ++ S G CQPC C+ + + +C+ +G C C+ G
Sbjct: 835 CPVGYTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTT 894
Query: 1122 GRTCSECQELHWGD--PGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG 1179
GR C C + ++GD C C C++ G + CH TG C CR V G RCD+C G
Sbjct: 895 GRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAG 954
Query: 1180 FSGIFPA--CHPCH 1191
G+ A C PC+
Sbjct: 955 TFGLQSARGCVPCN 968
Score = 159 bits (402), Expect = 2e-38
Identities = 93/277 (33%), Positives = 127/277 (45%), Gaps = 29/277 (10%)
Query: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF-GPTGCQACQCSHEGALS 840
PC+CN GS S C+ GQC C+ V G+RCD C G +G GC C C+ G+ S
Sbjct: 917 PCRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKS 976
Query: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRD 898
CE+ SGQC C+ G G +CDRC G + F C C C+ + C+ TG C+ C
Sbjct: 977 FDCEE-SGQCWCQPGVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCI-CPP 1034
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
+T GE C +C G + G C+ C C + Q C+C
Sbjct: 1035 NTIGEKCSKCAPNTWGHS-ITTG--CKACNCSTVGSLDFQCNVNTGQ--------CNCHP 1083
Query: 959 GYTGLRCEACAPGHFGDPSRPGGRCQLCEC---SGNIDPMDPD----ACDPHTGQCLRCL 1011
++G +C C+ GH+ P RC LC+C + D + +C TGQC C
Sbjct: 1084 KFSGAKCTECSRGHWNYP-----RCNLCDCFLPGTDATTCDSETKKCSCSDQTGQCT-CK 1137
Query: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQ 1048
+ EG HC C+PG G A+ +C GT Q
Sbjct: 1138 VNVEGIHCDRCRPGKFGLDAKNPLGCSSCYCFGTTTQ 1174
Score = 150 bits (380), Expect = 8e-36
Identities = 87/254 (34%), Positives = 121/254 (47%), Gaps = 24/254 (9%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
C C G +CE C +R R C C+C GH SC D+
Sbjct: 724 CQCPPGYTGSSCESCWPRHR----RVNGTIFGGICEPCQCFGHAESCD-DVT-------- 770
Query: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
G C C+ +T G +C+ C P FY +PTK + C+ C C + H D
Sbjct: 771 --GECLNCKDHTGGPYCDKCLPGFYGEPTKGTSED--CQPCACPLNIPSNNFSPTCHLDR 826
Query: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNAR--GTVPGSTPCDPN 487
+LGL+ C G RC++C +G+FG C+ CQCN ++PGS CD
Sbjct: 827 SLGLICDGCPVG--YTGPRCERCAEGYFGQPSVPGGSCQPCQCNDNLDFSIPGS--CDSL 882
Query: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQH 546
SGSC CK TGR C+ C G++G + D C+PC C+ GG+ C TGQC CR +
Sbjct: 883 SGSCLICKPGTTGRYCELCADGYFGDAVDAKNCQPCRCNAGGSFSEVCHSQTGQCECRAN 942
Query: 547 MVGRRCEQVQPGYF 560
+ G+RC++ + G F
Sbjct: 943 VQGQRCDKCKAGTF 956
Score = 135 bits (341), Expect = 3e-31
Identities = 98/370 (26%), Positives = 134/370 (36%), Gaps = 120/370 (32%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
C C+GHA C V G C+ CK +T G C++C + P + G S
Sbjct: 757 CQCFGHAESCDD-----------VTGECLNCKDHTGGPYCDKCLPGFYGEPTK----GTS 801
Query: 342 HACRKCEC------HGHTHSCHFDMAV----------------------YLASGNVSGGV 373
C+ C C + + +CH D ++ Y +V GG
Sbjct: 802 EDCQPCACPLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGGS 861
Query: 374 CDGCQHN------------------------TAGRHCELCRPFFYRDPTKDLRDPAVCRS 409
C CQ N T GR+CELC ++ D D C+
Sbjct: 862 CQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAV----DAKNCQP 917
Query: 410 CDCDPMGS-----------------QDGGRCDSHDDPALGLVS----------------- 435
C C+ GS G RCD GL S
Sbjct: 918 CRCNAGGSFSEVCHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSF 977
Query: 436 -----GQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS 490
GQC C+ V G +C +C G+F GC C+C+ G CDP +G
Sbjct: 978 DCEESGQCWCQPGVTGKKCDRCAHGYFNFQEG---GCTACECSHLGN-----NCDPKTGR 1029
Query: 491 CYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGR 550
C C G C +C P WG S GC+ C+C G+LD QC+ TGQC+C G
Sbjct: 1030 CICPPNTIGEKCSKCAPNTWGHSITT-GCKACNCSTVGSLDFQCNVNTGQCNCHPKFSGA 1088
Query: 551 RCEQVQPGYF 560
+C + G++
Sbjct: 1089 KCTECSRGHW 1098
Score = 133 bits (334), Expect = 2e-30
Identities = 181/827 (21%), Positives = 314/827 (37%), Gaps = 101/827 (12%)
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGR--------CQLCECSGNIDPMDPDACDPHTG 1005
C C GY+GL CEAC PG + S+PGGR C C+C+G+ CDP T
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SSLCDPETS 1434
Query: 1006 QCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDP-SS 1062
C C HHT G C C G++G + C +C C L+ ++ PS C +
Sbjct: 1435 ICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPS---CVAEGLDD 1491
Query: 1063 GQCPCLP-NVQGPSCDRCAPNFWNL--TSGHGCQPCACHPSRARGPTCNEFTGQCHCRAG 1119
+C P +G C+RCAP + G CQ C C P + C+ TG C CR G
Sbjct: 1492 YRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPG 1551
Query: 1120 FGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARG 1179
GR C C+ H G +C C + G+ G + R +Q
Sbjct: 1552 ATGRKCDGCKHWH-AREGWECVFCGDECTGL-------LLGDLA--------RLEQMVMS 1595
Query: 1180 FSGIFPACHPCHACFGDWDRVVQDL--AARTQRLEQRAQELQQTGVLGAFESSFWHMQEK 1237
+ P P +G + + Q+L QR +R +L + G + M E
Sbjct: 1596 INLTGPLPAPYKMLYG-LENMTQELKHLLSPQRAPERLIQLAE----GNLNTLVTEMNEL 1650
Query: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297
L + T Q E T + +G E + +L D V ++ N L
Sbjct: 1651 LTRATKV----TADGEQTGQDAERTNTRAKSLG---EFIKELARDAEAVNEKAIKLNETL 1703
Query: 1298 SGLERDRLALNL--TLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVP 1355
G + NL +++DQ + L+ N L I +AEA + L
Sbjct: 1704 -GTRDEAFERNLEGLQKEIDQMIKELRRKN-LETQKEIAEDELVAAEALLK-KVKKLFGE 1760
Query: 1356 SPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGD 1415
S N + E L D + + ++ + + A K+ ++ N +
Sbjct: 1761 SRGENEEMEKDLREKLADYKNKVDDAWDLLRE-ATDKIREANRLFAVNQKNMTALEKKKE 1819
Query: 1416 APCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILS 1475
A +G R + + G + A AD + + ++Q L L+
Sbjct: 1820 AV-------ESGKRQIENTLKEGNDILDEANRLADEINSIIDYVE-DIQTKLPPMSEELN 1871
Query: 1476 RVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEM 1535
+ Q + ++ A+ + +A + Q+ ++ L ++ K+ A +
Sbjct: 1872 DKIDDLSQEIKDRKLAE-KVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSN 1930
Query: 1536 VATRVLEL-SIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRAR 1594
+ + E + A+ + H A +A R L DA G ++++ ++L +A++
Sbjct: 1931 IKDYIDEAEKVAKEAKDLAHEATKLATGPRGLLKEDA-----KGCLQKSFRILNEAKKLA 1985
Query: 1595 SWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAV----ADTRDTEQTLYQVQERMAGAE 1650
+ ++ + ++ +E A G + + A DT L V+++ A
Sbjct: 1986 NDVKENEDHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDK---AR 2042
Query: 1651 RALSSAGERARQLDALLEALK-LKRAGNSLAASTAEETA---------------GSAQGR 1694
+A +A + Q+ L + L LK+ N LA S A+ A + +
Sbjct: 2043 QANDTAKDVLAQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNL 2102
Query: 1695 AQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDL 1741
QEA++L+ D+ + +K L + + + + Q R +A +
Sbjct: 2103 EQEADRLI-----DKLKPIKELEDNLKKNISEIKELINQARKQANSI 2144
Score = 129 bits (324), Expect = 3e-29
Identities = 73/191 (38%), Positives = 88/191 (46%), Gaps = 24/191 (12%)
Query: 849 QCLCRTGAFGLRCDRCQRGQWGFPS-------------CRPCVCNGHADECNTHTGACLG 895
+C C G GL C+ C G + S C PC CNGH+ C+ T C
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 896 CRDHTGGEHCERCIAGFHGDPR-LPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC 954
C+ HT G+ CERC G++G + LP C+ C CP S +F+ SC +
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLP--NDCQQCACPL-ISSSNNFSPSCVAEGLDDYRCT 1495
Query: 955 HCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMD--PDACDPHTGQCLRCLH 1012
C GY G CE CAPG+ G P PGG CQ CEC DP P CDP TG C C
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNPGGSCQECEC----DPYGSLPVPCDPVTGFC-TCRP 1550
Query: 1013 HTEGPHCAHCK 1023
G C CK
Sbjct: 1551 GATGRKCDGCK 1561
Score = 114 bits (286), Expect = 7e-25
Identities = 82/292 (28%), Positives = 119/292 (40%), Gaps = 44/292 (15%)
Query: 299 PAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHG---HTHS 355
P + + ICK T G CE C D Y + A D + C+ C C+ +
Sbjct: 876 PGSCDSLSGSCLICKPGTTGRYCELCADGY----FGDAVDAKN--CQPCRCNAGGSFSEV 929
Query: 356 CHFDMAVYLASGNVSGGVCDGCQHNTAG----RHCELCRPFFYRDPTKDLRDPAVC---- 407
CH NV G CD C+ T G R C C + + D + C
Sbjct: 930 CHSQTGQCECRANVQGQRCDKCKAGTFGLQSARGCVPCNCNSFGSKSFDCEESGQCWCQP 989
Query: 408 ----RSCDCDPMGS---QDGG--RCD-SHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF 457
+ CD G Q+GG C+ SH +G+C C + +G +C +C +
Sbjct: 990 GVTGKKCDRCAHGYFNFQEGGCTACECSHLGNNCDPKTGRCICPPNTIGEKCSKCAPNTW 1049
Query: 458 GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLL 517
G SI+ GC+ C C+ G++ C+ N+G C C +G C C GHW
Sbjct: 1050 GHSITT--GCKACNCSTVGSL--DFQCNVNTGQCNCHPKFSGAKCTECSRGHWNYPR--- 1102
Query: 518 GCRPCDCDVGGALDPQCD---------EGTGQCHCRQHMVGRRCEQVQPGYF 560
C CDC + G CD + TGQC C+ ++ G C++ +PG F
Sbjct: 1103 -CNLCDCFLPGTDATTCDSETKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKF 1153
Score = 98.2 bits (243), Expect = 6e-20
Identities = 66/205 (32%), Positives = 90/205 (43%), Gaps = 25/205 (12%)
Query: 310 CICKHNTRGLNCEQC-QDFYR--DLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLAS 366
C C GL+CE C FYR P C C+C+GH+ C + ++
Sbjct: 1380 CDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSI---- 1435
Query: 367 GNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSH 426
C CQH+TAG CE C +Y K L P C+ C C + S + S
Sbjct: 1436 -------CQNCQHHTAGDFCERCALGYY-GIVKGL--PNDCQQCACPLISSSNNF---SP 1482
Query: 427 DDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCD 485
A GL +C C G C++C G+ G + C+ C+C+ G++P PCD
Sbjct: 1483 SCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLP--VPCD 1540
Query: 486 PNSGSCYCKRLVTGRGCDRCLPGHW 510
P +G C C+ TGR CD C HW
Sbjct: 1541 PVTGFCTCRPGATGRKCDGC--KHW 1563
Score = 95.9 bits (237), Expect = 3e-19
Identities = 70/248 (28%), Positives = 94/248 (37%), Gaps = 57/248 (22%)
Query: 849 QCLCRTGAFGLRCDRCQRGQWGFP----------SCRPCVCNGHADECNTHT-------- 890
+C C G CD+C G P C C C+G A+EC
Sbjct: 306 RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYYDENVARRNLS 365
Query: 891 ----------GACLGCRDHTGGEHCERCIAGFHGDPRLP--YGGQCRPCPC-PEGPGSQR 937
G C+ C +T G +CE C GF + Y C+PC C P G ++
Sbjct: 366 LNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEV 425
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDP 997
H CHC+ G+ G+ C+ CA G+ G P C+ C CSG +
Sbjct: 426 CVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTGYPD-----CKACNCSG----LGS 476
Query: 998 DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH 1057
DP G C+ C + EG C+ CK GF NL N + C D+C
Sbjct: 477 KNEDPCFGPCI-CKENVEGGDCSRCKSGFF-------------NLQEDNWKGC---DECF 519
Query: 1058 CDPSSGQC 1065
C S +C
Sbjct: 520 CSGVSNRC 527
Score = 94.0 bits (232), Expect = 1e-18
Identities = 65/237 (27%), Positives = 102/237 (43%), Gaps = 41/237 (17%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTK--DLRDP 404
C C+GH +C D A + C+ C+HNT G C+ C P F++ P +
Sbjct: 287 CICYGHARACPLDPATNKSR-------CE-CEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVS----------GQC-RCKEHVVGTRCQQCR 453
C +C+C + C ++ A +S G C C ++ G C+ C
Sbjct: 339 TECEACNCHGKAEE----CYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCT 394
Query: 454 DGFF---GLSISDRLGCRRCQCNARGTVPGSTPCDPNS-------GSCYCKRLVTGRGCD 503
DGFF G+S + C+ C C+ G++ D GSC+CK G CD
Sbjct: 395 DGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCD 454
Query: 504 RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
RC G+ G C+ C+C G+ + D G C C++++ G C + + G+F
Sbjct: 455 RCARGYTGYPD----CKACNCSGLGSKNE--DPCFGPCICKENVEGGDCSRCKSGFF 505
Score = 93.2 bits (230), Expect = 2e-18
Identities = 77/257 (29%), Positives = 97/257 (37%), Gaps = 59/257 (22%)
Query: 877 CVCNGHADECN----THTGACLGCRDHTGGEHCERCIAGFHGDP----RLPYGGQCRPCP 928
C+C GHA C T+ C C +T G+ C++C GFH P +C C
Sbjct: 287 CICYGHARACPLDPATNKSRC-ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACN 345
Query: 929 CPEGPGSQRHFATSCHQDEYSQQI--------VC-HCRAGYTGLRCEACAPGHFGDPSRP 979
C G + ++ + + S I VC +C G+ CE C G F RP
Sbjct: 346 C-HGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFF----RP 400
Query: 980 GG-------RCQLCECSGNIDPMDP--DACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA 1030
G CQ C C DP+ + C R L P HCK GF G
Sbjct: 401 KGVSPNYPRPCQPCHC----DPIGSLNEVCVKDEKHARRGL----APGSCHCKTGFGGV- 451
Query: 1031 ARQSCHRCTCNLLGTNPQQCPSPDQCHC--------DPSSGQCPCLPNVQGPSCDRCAPN 1082
SC RC G P C+C DP G C C NV+G C RC
Sbjct: 452 ---SCDRCARGYTGY-----PDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSG 503
Query: 1083 FWNLTSGH--GCQPCAC 1097
F+NL + GC C C
Sbjct: 504 FFNLQEDNWKGCDECFC 520
Score = 90.5 bits (223), Expect = 1e-17
Identities = 67/253 (26%), Positives = 93/253 (36%), Gaps = 60/253 (23%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS----- 1034
GG C +C P+DP + +C C H+T G C C PGFH + R
Sbjct: 284 GGMC-ICYGHARACPLDPAT---NKSRC-ECEHNTCGDSCDQCCPGFHQKPWRAGTFLTK 338
Query: 1035 --CHRCTCNLLGTNPQQCPSPDQCHCDPS----------------SGQC-PCLPNVQGPS 1075
C C C+ ++C+ D + G C C N G +
Sbjct: 339 TECEACNCH---------GKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGIN 389
Query: 1076 CDRCAPNFWNLTS-----GHGCQPCACHPSRARGPTCNE---------FTGQCHCRAGFG 1121
C+ C F+ CQPC C P + C + G CHC+ GFG
Sbjct: 390 CETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFG 449
Query: 1122 GRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFS 1181
G +C C + G P C AC+C G+ + G C C+ V G C +C GF
Sbjct: 450 GVSCDRCARGYTGYP--DCKACNCS--GLGSKNEDPCFGPCICKENVEGGDCSRCKSGFF 505
Query: 1182 GI----FPACHPC 1190
+ + C C
Sbjct: 506 NLQEDNWKGCDEC 518
Score = 90.1 bits (222), Expect = 2e-17
Identities = 69/219 (31%), Positives = 89/219 (40%), Gaps = 46/219 (21%)
Query: 801 QCLCKPGVVGRRCDLCAPGYYGF---------GPT--GCQACQCSHEGALSSLCEKTSGQ 849
+C C G G C+ C PG+Y GPT C CQC+ SSLC+ +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH---SSLCDPETSI 1435
Query: 850 CL-CRTGAFGLRCDRCQRGQWGF-----PSCRPCVC------NGHADEC---NTHTGACL 894
C C+ G C+RC G +G C+ C C N + C C
Sbjct: 1436 CQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCT 1495
Query: 895 GCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIV 953
C G++CERC G+ G P P GG C+ C C P G C D +
Sbjct: 1496 ACPRGYEGQYCERCAPGYTGSPGNP-GGSCQECECDPYG-----SLPVPC--DPVTG--F 1545
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLC--ECSG 990
C CR G TG +C+ C H +R G C C EC+G
Sbjct: 1546 CTCRPGATGRKCDGCKHWH----AREGWECVFCGDECTG 1580
Score = 88.2 bits (217), Expect = 7e-17
Identities = 51/151 (33%), Positives = 70/151 (46%), Gaps = 25/151 (16%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYY---GFGPT---GCQACQCSHEGALSSLCEKTS---- 847
GG C+ C G C+ C G++ G P CQ C C G+L+ +C K
Sbjct: 375 GGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHAR 434
Query: 848 -----GQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNG----HADECNTHTGACLGCRD 898
G C C+TG G+ CDRC RG G+P C+ C C+G + D C G C+ C++
Sbjct: 435 RGLAPGSCHCKTGFGGVSCDRCARGYTGYPDCKACNCSGLGSKNEDPC---FGPCI-CKE 490
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPC 929
+ G C RC +GF + G C C C
Sbjct: 491 NVEGGDCSRCKSGFFNLQEDNWKG-CDECFC 520
Score = 85.9 bits (211), Expect = 3e-16
Identities = 68/242 (28%), Positives = 94/242 (38%), Gaps = 54/242 (22%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C C+ G C++C Y + ++G C CEC ++C
Sbjct: 983 GQCWCQPGVTGKKCDRCAHGYFNF-----QEG---GCTACECSHLGNNC----------- 1023
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
+ G C C NT G C C P + C++C+C +GS D +C+ +
Sbjct: 1024 DPKTGRCI-CPPNTIGEKCSKCAPNTWGHSIT-----TGCKACNCSTVGSLDF-QCNVN- 1075
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
+GQC C G +C +C G + C C C GT +T CD
Sbjct: 1076 -------TGQCNCHPKFSGAKCTECSRGHWNYP-----RCNLCDCFLPGT--DATTCDSE 1121
Query: 488 S---------GSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEG 537
+ G C CK V G CDRC PG +GL + + LGC C C QC E
Sbjct: 1122 TKKCSCSDQTGQCTCKVNVEGIHCDRCRPGKFGLDAKNPLGCSSCYC---FGTTTQCSEA 1178
Query: 538 TG 539
G
Sbjct: 1179 KG 1180
Score = 84.3 bits (207), Expect = 9e-16
Identities = 58/191 (30%), Positives = 81/191 (42%), Gaps = 23/191 (12%)
Query: 374 CDGCQHNTAGRHCELCRPFFYR---DPTKDLRDPAV--CRSCDCDPMGSQDGGRCDSHDD 428
CD C +G CE C P FYR P P + C C C+ S CD
Sbjct: 1380 CD-CPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSL----CD---- 1430
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
P + C+ H G C++C G++G+ C++C C + +P
Sbjct: 1431 PETSICQN---CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAE 1487
Query: 489 G-----SCYCKRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQCH 542
G C R G+ C+RC PG+ G + G C+ C+CD G+L CD TG C
Sbjct: 1488 GLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCT 1547
Query: 543 CRQHMVGRRCE 553
CR GR+C+
Sbjct: 1548 CRPGATGRKCD 1558
Score = 77.0 bits (188), Expect = 2e-13
Identities = 172/798 (21%), Positives = 274/798 (34%), Gaps = 149/798 (18%)
Query: 1064 QCPCLPNVQGPSCDRCAPNFWNLTSGHG----------CQPCACH--------------- 1098
+C C G SC+ C P F+ L S G C PC C+
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGHSSLCDPETSICQN 1438
Query: 1099 ------------------------PSRARGPTC------NEFTGQC-----------HCR 1117
P+ + C N F+ C C
Sbjct: 1439 CQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYRCTACP 1498
Query: 1118 AGFGGRTCSECQELHW---GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD 1174
G+ G+ C C + G+PG C C+CD G C TG C+CRPG +G +CD
Sbjct: 1499 RGYEGQYCERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCD 1558
Query: 1175 QCARGFSGIFPACHPC-HACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWH 1233
C + C C C G ++ DLA RLEQ + TG L A +
Sbjct: 1559 GCKHWHAREGWECVFCGDECTG---LLLGDLA----RLEQMVMSINLTGPLPAPYKMLYG 1611
Query: 1234 MQEKLGIVQGIVGARNTSAASTAQLVEAT-EELRREIGEATEHLTQLEAD----LTDVQD 1288
++ ++ ++ + + QL E L E+ E T++ AD D +
Sbjct: 1612 LENMTQELKHLLSPQR-APERLIQLAEGNLNTLVTEMNELLTRATKVTADGEQTGQDAER 1670
Query: 1289 ENFNA---NHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAER 1345
N A + L RD A+N +L++ L + F + ++ Q + R
Sbjct: 1671 TNTRAKSLGEFIKELARDAEAVNEKAIKLNETLG-TRDEAFERNLEGLQKEIDQMIKELR 1729
Query: 1346 RANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDI 1405
R N L ++ EAL+ K+ F N+ L L D
Sbjct: 1730 RKN---LETQKEIAEDELV--AAEALLKKVKKLFGESRGENEEMEKDLRE-----KLADY 1779
Query: 1406 NELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQR 1465
V A AT A Q L A + + +++
Sbjct: 1780 KNKVDDAWDLLREATDKIREANRLFAVNQKNMTALEKKKEAVESG---------KRQIEN 1830
Query: 1466 ALAEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ 1525
L EG IL E R A E D E+ N ++ +L Q +KD
Sbjct: 1831 TLKEGNDILD---EANRLADEINSIIDYVEDIQTKLPPMSEELNDKIDDLSQEIKDRKLA 1887
Query: 1526 E---GADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRR 1582
E A+ + ++ + + I A+ I A A + ++ D +
Sbjct: 1888 EKVSQAESHAAQLNDSSAVLDGILDEAKNISFNATAAFKAYSNIKDY----------IDE 1937
Query: 1583 AEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIR------GAVADTRDTE 1636
AE++ A+ A+ A + + A + L+E A+G Q + R D ++ E
Sbjct: 1938 AEKV---AKEAKDLAHEATKLATGPRGLLKE--DAKGCLQKSFRILNEAKKLANDVKENE 1992
Query: 1637 QTLYQVQERMAGAER----ALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQ 1692
L ++ R+ A+ L + + +L A+ K A A +TA
Sbjct: 1993 DHLNGLKTRIENADARNGDLLRTLNDTLGKLSAIPNDTAAKLQAVKDKARQANDTAKDVL 2052
Query: 1693 GRAQEAEQLLRG------PLGDQYQTVKALAERKAQGVLAAQARA--EQLRDEARDLLQA 1744
+ E Q L G L D A+ + ++ + A A A + L EA L+
Sbjct: 2053 AQITELHQNLDGLKKNYNKLADSVAKTNAVVKDPSKNKIIADADATVKNLEQEADRLI-- 2110
Query: 1745 AQDKLQRLQELEGTYEEN 1762
DKL+ ++ELE ++N
Sbjct: 2111 --DKLKPIKELEDNLKKN 2126
Score = 75.9 bits (185), Expect = 3e-13
Identities = 66/231 (28%), Positives = 95/231 (41%), Gaps = 41/231 (17%)
Query: 355 SCHFDMAV-YLASGNVSGGV--CDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCD 411
S + + AV Y G+++ V C C G CE C P R +C C
Sbjct: 702 SVNLESAVSYPTDGSIAAAVEVCQ-CPPGYTGSSCESCWPRHRR--VNGTIFGGICEPCQ 758
Query: 412 CDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRL-GCRR 469
C G +S DD V+G+C CK+H G C +C GF+G C+
Sbjct: 759 CF-------GHAESCDD-----VTGECLNCKDHTGGPYCDKCLPGFYGEPTKGTSEDCQP 806
Query: 470 CQCNARGTVPGSTPCDPNSGSCYCKRLV-----------TGRGCDRCLPGHWGLSHDLLG 518
C C P + P + S +C+ R + TG C+RC G++G G
Sbjct: 807 CAC------PLNIPSNNFSPTCHLDRSLGLICDGCPVGYTGPRCERCAEGYFGQPSVPGG 860
Query: 519 -CRPCDCD--VGGALDPQCDEGTGQCH-CRQHMVGRRCEQVQPGYFRPFLD 565
C+PC C+ + ++ CD +G C C+ GR CE GYF +D
Sbjct: 861 SCQPCQCNDNLDFSIPGSCDSLSGSCLICKPGTTGRYCELCADGYFGDAVD 911
Score = 69.7 bits (169), Expect = 2e-11
Identities = 50/151 (33%), Positives = 61/151 (40%), Gaps = 31/151 (20%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYGFG---PTGCQACQCSHE 836
+PCQCN SL C+P C C+ G C+ CA GYYG P CQ C C
Sbjct: 1418 VPCQCNGHSSL---CDPETSICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCAC--- 1471
Query: 837 GALSSLCEKTSGQCL-----------CRTGAFGLRCDRCQRGQWGFP-----SCRPCVCN 880
L S S C+ C G G C+RC G G P SC+ C C+
Sbjct: 1472 -PLISSSNNFSPSCVAEGLDDYRCTACPRGYEGQYCERCAPGYTGSPGNPGGSCQECECD 1530
Query: 881 GHAD---ECNTHTGACLGCRDHTGGEHCERC 908
+ C+ TG C CR G C+ C
Sbjct: 1531 PYGSLPVPCDPVTGFCT-CRPGATGRKCDGC 1560
Score = 69.3 bits (168), Expect = 3e-11
Identities = 53/146 (36%), Positives = 65/146 (44%), Gaps = 21/146 (14%)
Query: 753 GLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRR 812
G+V + + CA LIS S N P C +G C C G G+
Sbjct: 1457 GIVKGLPNDCQQCACPLISSS----NNFSP-SCVAEGLDDYRCTA------CPRGYEGQY 1505
Query: 813 CDLCAPGYYGF--GPTG-CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQW 869
C+ CAPGY G P G CQ C+C G+L C+ +G C CR GA G +CD C+ W
Sbjct: 1506 CERCAPGYTGSPGNPGGSCQECECDPYGSLPVPCDPVTGFCTCRPGATGRKCDGCK--HW 1563
Query: 870 GFPSCRPCVCNGHADECNTHTGACLG 895
CV G DEC TG LG
Sbjct: 1564 HAREGWECVFCG--DEC---TGLLLG 1584
Score = 67.8 bits (164), Expect = 9e-11
Identities = 50/180 (27%), Positives = 67/180 (37%), Gaps = 42/180 (23%)
Query: 1056 CHCDPSSGQ--CPCLPNVQGPSCDRCAPNFWNLTSGHG-------CQPCACHPSR----- 1101
C DP++ + C C N G SCD+C P F G C+ C CH
Sbjct: 296 CPLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCHGKAEECYY 355
Query: 1102 ----ARGPTCNEFTGQ-------CHCRAGFGGRTCSECQELHWGDPGLQ------CHACD 1144
AR G+ +C G C C + + G+ C C
Sbjct: 356 DENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRPKGVSPNYPRPCQPCH 415
Query: 1145 CDSRGIDTPQCHRFTGH---------CSCRPGVSGVRCDQCARGFSGIFPACHPCHACFG 1195
CD G C + H C C+ G GV CD+CARG++G +P C C+ C G
Sbjct: 416 CDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARGYTG-YPDCKACN-CSG 473
Score = 65.9 bits (159), Expect = 3e-10
Identities = 63/259 (24%), Positives = 87/259 (33%), Gaps = 67/259 (25%)
Query: 775 LIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYG--------FGPT 826
+ Y A C +P + S +C C+ G CD C PG++ T
Sbjct: 288 ICYGHARACPLDPATNKS--------RCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKT 339
Query: 827 GCQACQCSHEGALSSLCEKTS---------------GQCL-CRTGAFGLRCDRCQRGQW- 869
C+AC C + E + G C+ C G+ C+ C G +
Sbjct: 340 ECEACNCHGKAEECYYDENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFR 399
Query: 870 ------GFP-SCRPCVCNGHA--------DECNTHTGACLG---CRDHTGGEHCERCIAG 911
+P C+PC C+ DE + G G C+ GG C+RC G
Sbjct: 400 PKGVSPNYPRPCQPCHCDPIGSLNEVCVKDEKHARRGLAPGSCHCKTGFGGVSCDRCARG 459
Query: 912 FHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG 971
+ G P C+ C C G GS+ C C C+ G C C G
Sbjct: 460 YTGYP------DCKACNC-SGLGSKNE--DPCFGP-------CICKENVEGGDCSRCKSG 503
Query: 972 HFGDPSRPGGRCQLCECSG 990
F C C CSG
Sbjct: 504 FFNLQEDNWKGCDECFCSG 522
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/171 (27%), Positives = 70/171 (40%), Gaps = 29/171 (16%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C GH+S C P + C+H+T G CE+C L + G +
Sbjct: 1420 CQCNGHSSLCDPETSICQN----------CQHHTAGDFCERCA-----LGYYGIVKGLPN 1464
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
C++C C + S +F + +A G + C C G++CE C P + P
Sbjct: 1465 DCQQCACPLISSSNNFSPSC-VAEG-LDDYRCTACPRGYEGQYCERCAPGYTGSPG---N 1519
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
C+ C+CDP GS CD V+G C C+ G +C C+
Sbjct: 1520 PGGSCQECECDPYGSLP-VPCDP--------VTGFCTCRPGATGRKCDGCK 1561
Score = 57.4 bits (137), Expect = 1e-07
Identities = 42/140 (30%), Positives = 58/140 (41%), Gaps = 22/140 (15%)
Query: 437 QCRCKEHVVGTRCQQCRDGFF-------GLSISDRLG-CRRCQCNARGTVPGSTPCDPNS 488
+C C G C+ C GF+ G + LG C CQCN S+ CDP +
Sbjct: 1379 KCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCNGH-----SSLCDPET 1433
Query: 489 GSCY-CKRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDV---GGALDPQC-DEGTGQCH 542
C C+ G C+RC G++G+ L C+ C C + P C EG
Sbjct: 1434 SICQNCQHHTAGDFCERCALGYYGIVKGLPNDCQQCACPLISSSNNFSPSCVAEGLDDYR 1493
Query: 543 CR---QHMVGRRCEQVQPGY 559
C + G+ CE+ PGY
Sbjct: 1494 CTACPRGYEGQYCERCAPGY 1513
Score = 44.3 bits (103), Expect = 0.001
Identities = 31/96 (32%), Positives = 40/96 (41%), Gaps = 15/96 (15%)
Query: 475 RGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG---------CRPCDCD 525
RGT TP C C +G C+ CLPG + L G C PC C+
Sbjct: 1366 RGTT--MTPPADLIEKCDCPLGYSGLSCEACLPGFYRLRSQPGGRTPGPTLGTCVPCQCN 1423
Query: 526 VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
+L CD T C +C+ H G CE+ GY+
Sbjct: 1424 GHSSL---CDPETSICQNCQHHTAGDFCERCALGYY 1456
Score = 42.7 bits (99), Expect = 0.003
Identities = 33/105 (31%), Positives = 40/105 (38%), Gaps = 26/105 (24%)
Query: 483 PCDP--NSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPCDCDVGGALDPQC 534
P DP N C C+ G CD+C PG W G C C+C G A +
Sbjct: 297 PLDPATNKSRCECEHNTCGDSCDQCCPGFHQKPWRAGTFLTKTECEACNCH-GKAEECYY 355
Query: 535 DE----------------GTGQC-HCRQHMVGRRCEQVQPGYFRP 562
DE G G C +C Q+ G CE G+FRP
Sbjct: 356 DENVARRNLSLNIRGKYIGGGVCINCTQNTAGINCETCTDGFFRP 400
Score = 41.2 bits (95), Expect = 0.009
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 7/74 (9%)
Query: 777 YNGALPCQ-CNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGP---TGCQACQ 832
Y G C+ CN G S +P G C+CK V G C C G++ GC C
Sbjct: 460 YTGYPDCKACNCSGLGSKNEDPCFGPCICKENVEGGDCSRCKSGFFNLQEDNWKGCDECF 519
Query: 833 CSHEGALSSLCEKT 846
CS +S+ C+ +
Sbjct: 520 CS---GVSNRCQSS 530
Score = 39.3 bits (90), Expect = 0.035
Identities = 47/223 (21%), Positives = 98/223 (43%), Gaps = 30/223 (13%)
Query: 1566 LADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAI 1625
+ +++ +L R EQ QDA R + A K E ++ E A+ A+ + + AI
Sbjct: 1644 VTEMNELLTRATKVTADGEQTGQDAERTNTRA---KSLGEFIK---ELARDAEAVNEKAI 1697
Query: 1626 RGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAE 1685
+ + +T T ++ + G ++ ++D +++ +L+R AE
Sbjct: 1698 K--LNETLGTRDEAFE--RNLEGLQK----------EIDQMIK--ELRRKNLETQKEIAE 1741
Query: 1686 ETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAA 1745
+ +A+ ++ ++L G+ + K L E+ A + D+A DLL+ A
Sbjct: 1742 DELVAAEALLKKVKKLFGESRGENEEMEKDLREKLAD--------YKNKVDDAWDLLREA 1793
Query: 1746 QDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQAIN 1788
DK++ L ++N ALE K ++ + ++ + L+ N
Sbjct: 1794 TDKIREANRLFAVNQKNMTALEKKKEAVESGKRQIENTLKEGN 1836
Score = 36.6 bits (83), Expect = 0.23
Identities = 69/363 (19%), Positives = 137/363 (37%), Gaps = 56/363 (15%)
Query: 1440 LSCNGAAATADLALGR-ARHTQAELQRALAEGGSILSRVAETRRQASEAQQ-RAQAALDK 1497
+ N T D A R Q E+ + + E + + ET+++ +E + A+A L K
Sbjct: 1697 IKLNETLGTRDEAFERNLEGLQKEIDQMIKE---LRRKNLETQKEIAEDELVAAEALLKK 1753
Query: 1498 ANASRGQVEQANQELQ-ELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLA 1556
G+ N+E++ +L + + D+ N+ D + ++ E + + Q A
Sbjct: 1754 VKKLFGESRGENEEMEKDLREKLADYKNKVDDAWDLLREATDKIREANRLFAVNQKNMTA 1813
Query: 1557 GAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSWAEDEKQKAETVQAALEEAQR 1616
E+ + V++ + ++ +L +A R E +Q L
Sbjct: 1814 ---LEKKKEA--VESGKRQIENTLKEGNDILDEANRLADEINSIIDYVEDIQTKLPPMSE 1868
Query: 1617 AQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAG 1676
+ + D + + E+++ AE + + + LD +L+ K +
Sbjct: 1869 ELNDKIDDLSQEIKDRK--------LAEKVSQAESHAAQLNDSSAVLDGILDEAK-NISF 1919
Query: 1677 NSLAA-----------STAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVL 1725
N+ AA AE+ A A+ A EA +L GP G
Sbjct: 1920 NATAAFKAYSNIKDYIDEAEKVAKEAKDLAHEATKLATGPRG------------------ 1961
Query: 1726 AAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRSVLQ 1785
L+++A+ LQ + L ++L +ENE L +++ +AR +L+
Sbjct: 1962 -------LLKEDAKGCLQKSFRILNEAKKLANDVKENEDHLNGLKTRIENADARNGDLLR 2014
Query: 1786 AIN 1788
+N
Sbjct: 2015 TLN 2017
>gi|38045910 laminin alpha 3 subunit isoform 1 [Homo sapiens]
Length = 3333
Score = 257 bits (656), Expect = 8e-68
Identities = 201/701 (28%), Positives = 286/701 (40%), Gaps = 171/701 (24%)
Query: 1 MELTSRERGR--GQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRG-SCYPATGDLLVG 57
M +R RGR G LP L L+L VL A A A P G + G S +P +L
Sbjct: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDP---GAAAGLSLHPTYFNL--A 55
Query: 58 RADRLTASSTCGLNGP-----QP--YCIV---------SHLQDEKKCFLCDSRRPFSARD 101
A R+ A++TCG GP QP YC + H + C C+S P A
Sbjct: 56 EAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKA-- 113
Query: 102 NPHSHRIQNVVTSFAPQRRAAWWQSE-----NGIPAVTIQLDLEAEFHFTHLIMTFKTF- 155
H + N + WWQS V + LDL FH ++++ F
Sbjct: 114 ----HPVTNAIDG-----SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSP 164
Query: 156 RPAAMLVERSADFGRTWHVYRYFSY---DCGADFPGVPLAPPRHWDDVVCESRYSEIEPS 212
RP ++ERS DFG T+ ++YF++ DC +F DDV+C + YS I P
Sbjct: 165 RPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPL 224
Query: 213 TEGEVIYRVLDPAIPIPD-PYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IRE 268
GEV+ +++ + +S ++ K TN+R+ R +TL +L+ + +
Sbjct: 225 ENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTR 284
Query: 269 KYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFY 328
+YYY++ ++ + G C C GHA C + E + C C+H+T G C++C Y
Sbjct: 285 RYYYSIKDISIGGQCVCNGHAEVCNIN-----NPEKLFR--CECQHHTCGETCDRCCTGY 337
Query: 329 RDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS-------GGVCDGCQHNT 381
WRPA SH C C CHGH +C++D V +++ GGVC CQHNT
Sbjct: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397
Query: 382 AGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGS----QDGGRC-------------- 423
AG +CE C +YR + P C C CDP + Q GRC
Sbjct: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKC 457
Query: 424 --------------------DSHDDPALGLVS-----------------GQCRCKEHVVG 446
S +DP G + G+C C+ V G
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEG 517
Query: 447 TRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCL 506
RC CR GF+ I C+ C C+A G+ PC +G C C+ VTG+ CDRCL
Sbjct: 518 PRCDTCRSGFYSFPI-----CQACWCSALGSY--QMPCSSVTGQCECRPGVTGQRCDRCL 570
Query: 507 PG--------------------------------------------HWGL-SHDLLGCRP 521
G +W L + GC
Sbjct: 571 SGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630
Query: 522 CDCDVGGALD--PQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
C C G + +C +G G CHC+ H+ G C+ + GYF
Sbjct: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Score = 169 bits (428), Expect = 2e-41
Identities = 124/430 (28%), Positives = 171/430 (39%), Gaps = 110/430 (25%)
Query: 849 QCLCRTGAFGLRCDRCQRG----QWGFPS------CRPCVCNGHADEC------------ 886
+C C+ G CDRC G +W + C C C+GHA C
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 887 -NTHT-----GACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQ--CRPCPC-PEGPGSQR 937
NT G C+ C+ +T G +CE+C G++ +P C PC C PE
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE------ 431
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDP----------SRPG------G 981
A C Q CHC+ + G CE CA G++ P S P G
Sbjct: 432 -HADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
Query: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCN 1041
+ C+C N++ + P+ CD H G+CL C EGP C C+ GF+ C C C+
Sbjct: 487 DIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCS 539
Query: 1042 LLGTNPQQCPSP---------------DQC--------HCDPSS-------------GQC 1065
LG+ C S D+C HC SS G C
Sbjct: 540 ALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC 599
Query: 1066 PCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPT--CNEFTGQCHCRAGFG 1121
C +V+GP+C RC +WNL + GC C CH + T C + G CHC++ G
Sbjct: 600 QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVG 659
Query: 1122 GRTCSECQELHWG---DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCAR 1178
G +C C++ ++ C C CD G + C +G C CR V G C +
Sbjct: 660 GDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPEN 719
Query: 1179 GFSGIFPACH 1188
+ FP H
Sbjct: 720 NY--YFPDLH 727
Score = 167 bits (424), Expect = 7e-41
Identities = 117/392 (29%), Positives = 167/392 (42%), Gaps = 113/392 (28%)
Query: 283 CFCYGHASECAPAPG-----APAHAEGMVHGA--CI-CKHNTRGLNCEQCQDFYRDLPWR 334
C C+GHAS C P A + +G+ G CI C+HNT G+NCEQC Y +R
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY----YR 411
Query: 335 P------AEDG---------HSHACR----KCECHGHTH--SC--------HFDMAVYL- 364
P A DG H+ C +C C + H +C +F + +
Sbjct: 412 PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 365 ------------ASGNVSG----------GVCDG-----CQHNTAGRHCELCRPFFYRDP 397
+G++ G +CD C+ G C+ CR FY P
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP 531
Query: 398 TKDLRDPAVCRSCDCDPMGSQD-----------------GGRCD---------------- 424
+C++C C +GS G RCD
Sbjct: 532 --------ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSS 583
Query: 425 SHDDPALGLVS--GQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGST 482
S DPA + S G C+CK HV G C +C+ ++ L + GC C+C+ GTV G+
Sbjct: 584 SACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
Query: 483 PCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEGTGQC 541
C G C+CK V G CD C G++ L + GC+ C CD+GGAL C +G C
Sbjct: 644 ECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVC 703
Query: 542 HCRQHMVGRRCEQVQPGYFRPFLDHLIWEAED 573
CR+H+VG+ C++ + Y+ P L H+ +E ED
Sbjct: 704 QCREHVVGKVCQRPENNYYFPDLHHMKYEIED 735
Score = 149 bits (375), Expect = 3e-35
Identities = 107/363 (29%), Positives = 143/363 (39%), Gaps = 71/363 (19%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYYG-FG-----PTGCQACQCSHEGALSSLCEKTSGQCL 851
GG C+ C+ G C+ CA GYY +G P GC C C E A CE+ SG+C
Sbjct: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
Query: 852 CRTGAFGLRCDRCQRGQWGFPSC---------------------RPCVCNGHA---DECN 887
C+ G C++C G + FP C + C CN + C+
Sbjct: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
Query: 888 THTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDE 947
H G CL CR G C+ C +GF+ P C+ C C Q ++ Q
Sbjct: 505 AH-GRCL-CRPGVEGPRCDTCRSGFYSFP------ICQACWCSALGSYQMPCSSVTGQ-- 554
Query: 948 YSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDP-DACDPHTGQ 1006
C CR G TG RC+ C G + P C G+ DP + + G
Sbjct: 555 ------CECRPGVTGQRCDRCLSGAYDFP----------HCQGSSSACDPAGTINSNLGY 598
Query: 1007 CLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQ 1064
C +C H EGP C+ CK + + C C C+ GT C G
Sbjct: 599 C-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGT------VSGTGECRQGDGD 651
Query: 1065 CPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCRAGFGG 1122
C C +V G SCD C ++ L + GCQ C C A C+ +G C CR G
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVG 711
Query: 1123 RTC 1125
+ C
Sbjct: 712 KVC 714
Score = 147 bits (370), Expect = 1e-34
Identities = 101/343 (29%), Positives = 138/343 (40%), Gaps = 71/343 (20%)
Query: 877 CVCNGHADECNTHTGACL---GCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRPCPC 929
CVCNGHA+ CN + L C+ HT GE C+RC G++ P +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 930 PE-------GPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHF---GDPSR 978
P +R A+ Q Y+ VC +C+ G+ CE CA G++ G P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 979 PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRC 1038
C C C DP D C+ +G+C HCKP FHG +C +C
Sbjct: 419 APDGCIPCSC----DPEHADGCEQGSGRC-------------HCKPNFHGD----NCEKC 457
Query: 1039 T--------CNLLGTNPQQCPSPDQ--------CHCD---------PSSGQCPCLPNVQG 1073
C + P PS + C C+ + G+C C P V+G
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEG 517
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHW 1133
P CD C F++ CQ C C + C+ TGQC CR G G+ C C +
Sbjct: 518 PRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
Query: 1134 GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176
P Q + CD G + G+C C+ V G C +C
Sbjct: 575 DFPHCQGSSSACDPAG----TINSNLGYCQCKLHVEGPTCSRC 613
Score = 141 bits (356), Expect = 5e-33
Identities = 95/332 (28%), Positives = 134/332 (40%), Gaps = 55/332 (16%)
Query: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF------------GP 825
+G +PC C+P+ + C G+C CKP G C+ CA GYY F P
Sbjct: 421 DGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 826 TG-------CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCV 878
+ + C C+ EG L +C+ G+CLCR G G RCD C+ G + FP C+ C
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACW 537
Query: 879 CN---GHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
C+ + C++ TG C CR G+ C+RC++G + P G C P G +
Sbjct: 538 CSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQ--GSSSACD-PAGTIN 593
Query: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGNIDP 994
S C C+ G C C ++ D P G C C+C
Sbjct: 594 -------------SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKCHKAGTV 639
Query: 995 MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPS 1052
C G C C H G C C+ G+ ++ C C C++ G C
Sbjct: 640 SGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698
Query: 1053 PDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
P SG C C +V G C R N++
Sbjct: 699 P--------SGVCQCREHVVGKVCQRPENNYY 722
Score = 140 bits (353), Expect = 1e-32
Identities = 73/207 (35%), Positives = 98/207 (47%), Gaps = 54/207 (26%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRC 861
C C P G C C+PGYY H+G + G+C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYR-----------DHKGLYT-------GRCV---------- 1685
Query: 862 DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
PC CNGH+++C +G C+ C+ +T GEHCERC G++G+
Sbjct: 1686 --------------PCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA---VH 1728
Query: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
G CR CPCP FAT C + + C C+AGYTG +CE CAPG+FG+P + GG
Sbjct: 1729 GSCRACPCPH----TNSFATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
Query: 982 RCQLCECSGNIDPMDPDACDPHTGQCL 1008
CQ C C+ N +C P TG C+
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 136 bits (342), Expect = 2e-31
Identities = 76/230 (33%), Positives = 99/230 (43%), Gaps = 52/230 (22%)
Query: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGV 808
C + + S C SL + GALPC+C+P G+ C+P GGQC C+P V
Sbjct: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
Query: 809 VGRRCDLCAPGYYGF------------------------------------------GPT 826
+GR+C CA G+YGF
Sbjct: 1292 IGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA 1351
Query: 827 GCQACQCSHEGALSSL---CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHA 883
GC+ C CS G + + C++ SGQC C+ G +CDRC G + FP C PC CN
Sbjct: 1352 GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDG 1411
Query: 884 DE---CNTHTGACLGCRDHTGGEHCERCIAG-FHGDPRLPYGGQCRPCPC 929
E C+ TGACL C+++ G C C G FH DP G C C C
Sbjct: 1412 TEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKG--CTSCFC 1458
Score = 115 bits (289), Expect = 3e-25
Identities = 78/289 (26%), Positives = 111/289 (38%), Gaps = 55/289 (19%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG-----RCQLCECSGNIDP 994
A C+ + + C C+ G C+ C G+ RP C+ C C G+
Sbjct: 305 AEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASN 364
Query: 995 M--DPDACDPHT-----------GQCLRCLHHTEGPHCAHCKPGFHGQA-----ARQSCH 1036
DPD G C+ C H+T G +C C G++ A C
Sbjct: 365 CYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCI 424
Query: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTS-------- 1088
C+C+ P+ C+ SG+C C PN G +C++CA ++N
Sbjct: 425 PCSCD-----PEHADG-----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFP 474
Query: 1089 ----------GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGL 1138
+ C C+ C+ G+C CR G G C C+ + P
Sbjct: 475 VSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFP-- 531
Query: 1139 QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPAC 1187
C AC C + G C TG C CRPGV+G RCD+C G + FP C
Sbjct: 532 ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG-AYDFPHC 579
Score = 115 bits (288), Expect = 4e-25
Identities = 67/193 (34%), Positives = 86/193 (44%), Gaps = 34/193 (17%)
Query: 371 GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGR--CDSHDD 428
GG C CQ N GR C C Y P C+ C C GR C+
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC--------GRRLCEE--- 1321
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP-CDPN 487
++GQCRC V +C+ C F S GC C C+ RGT+ + P CD +
Sbjct: 1322 -----MTGQCRCPPRTVRPQCEVCETHSF--SFHPMAGCEGCNCSRRGTIEAAMPECDRD 1374
Query: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
SG C CK +TGR CDRC G + C PC+C+ G CD GTG C C++++
Sbjct: 1375 SGQCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 548 VGRRCEQVQPGYF 560
G C + G F
Sbjct: 1431 EGTECNVCREGSF 1443
Score = 110 bits (276), Expect = 9e-24
Identities = 55/181 (30%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Query: 953 VCHCRAGYTGLRCEACAPGHFGD-PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
+C C Y G C+ C+PG++ D GRC C C+G+ + C +G C+ C
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQ 1707
Query: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
H+T G HC C+ G++G A SC C C P C + +C C
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPC------PHTNSFATGCVVNGGDVRCSCKAGY 1761
Query: 1072 QGPSCDRCAPNFWNLTS--GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQ 1129
G C+RCAP ++ G CQPC+C+ + G +C+ TG C + EC
Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECD 1820
Query: 1130 E 1130
+
Sbjct: 1821 D 1821
Score = 109 bits (272), Expect = 3e-23
Identities = 54/139 (38%), Positives = 68/139 (48%), Gaps = 13/139 (9%)
Query: 1057 HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHC 1116
HC P GQCPC PNV G C RCA + C+PC+C C E TGQC C
Sbjct: 1277 HCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR-----LCEEMTGQCRC 1328
Query: 1117 RAGFGGRTCSECQELHWG-DPGLQCHACDCDSRG---IDTPQCHRFTGHCSCRPGVSGVR 1172
C C+ + P C C+C RG P+C R +G C C+P ++G +
Sbjct: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
Query: 1173 CDQCARGFSGIFPACHPCH 1191
CD+CA GF FP C PC+
Sbjct: 1389 CDRCASGFYR-FPECVPCN 1406
Score = 102 bits (253), Expect = 4e-21
Identities = 65/219 (29%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 986 CEC--SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLL 1043
CEC +G P C P GQC C + G C C G +G C C+C
Sbjct: 1266 CECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCG-- 1315
Query: 1044 GTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPS--- 1100
+ C+ +GQC C P P C+ C + ++ GC+ C C
Sbjct: 1316 -----------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
Query: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTG 1160
A P C+ +GQC C+ GR C C + P +C C+C+ G + C TG
Sbjct: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
Query: 1161 HCSCRPGVSGVRCDQCARGFSGIFPA----CHPCHACFG 1195
C C+ V G C+ C G + PA C C CFG
Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG 1460
Score = 95.5 bits (236), Expect = 4e-19
Identities = 71/237 (29%), Positives = 91/237 (38%), Gaps = 48/237 (20%)
Query: 291 ECAP--APGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCE 348
EC P A G EG G C C+ N G C +C + P C+ C
Sbjct: 1267 ECHPTGATGPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCS 1313
Query: 349 CHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCR 408
C C +M G C C T CE+C + A C
Sbjct: 1314 CGRRL--CE-EMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGCE 1354
Query: 409 SCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
C+C G+ + + D SGQCRCK + G +C +C GF+ C
Sbjct: 1355 GCNCSRRGTIEAAMPECDRD------SGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
C CN GT PG CDP +G+C CK V G C+ C G + L +L GC C C
Sbjct: 1404 PCNCNRDGTEPGV--CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 94.7 bits (234), Expect = 7e-19
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 17/160 (10%)
Query: 763 EACAPLLISLSTLIYNG-ALPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGY 820
+ C+P +Y G +PC CN S++C G C+ C+ G C+ C GY
Sbjct: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGY 1722
Query: 821 YGFGPTG-CQACQCSHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP----- 872
YG G C+AC C H + ++ C G +C C+ G G +C+RC G +G P
Sbjct: 1723 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
Query: 873 SCRPCVC--NGHADECNTHTGACLG--CRDHTGGEHCERC 908
SC+PC C NG C+ TG C+ +D + E C+ C
Sbjct: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/182 (30%), Positives = 79/182 (43%), Gaps = 30/182 (16%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
C C G +C+ C Y +R + ++ C C C+GH++ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
G+C CQHNTAG HCE C+ +Y + CR+C C S G + D
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDV 1753
Query: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
+C CK GT+C++C G+FG C+ C CN+ G + GS C P +G
Sbjct: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GS--CHPLTG 1803
Query: 490 SC 491
C
Sbjct: 1804 DC 1805
Score = 90.1 bits (222), Expect = 2e-17
Identities = 161/787 (20%), Positives = 276/787 (35%), Gaps = 111/787 (14%)
Query: 1016 GPHCAHCKPGFHGQAARQSCHRCT-CNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQG 1073
G C C PG++ RC CN G + Q C SG C C N G
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---------CQDGSGICVNCQHNTAG 1712
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSR--ARGPTCNEFTGQCHCRAGFGGRTCSECQEL 1131
C+RC ++ C+ C C + A G N +C C+AG+ G C C
Sbjct: 1713 EHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 1772
Query: 1132 HWGDP---GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACH 1188
++G+P G C C C+S G CH TG C + ++ C
Sbjct: 1773 YFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEE-----------CD 1820
Query: 1189 PCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGAR 1248
C +C ++ DLA ++L +LQ HM+ + ++ +
Sbjct: 1821 DCDSCV---MTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 1877
Query: 1249 NTSAASTAQLVEATEELRREIGEATEHLTQ-LEADLTDVQDENFNANHALSGLERDRLAL 1307
++ ++ +E E ++ + E L + + + Q N N N A + + +
Sbjct: 1878 RSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKI 1937
Query: 1308 NLTLRQLDQHLDLLKHSNFLGAYDSIRHA--HSQSAEAERRANTSALAVPSPVSNSASAR 1365
+R + H+ L + S G +++ + AEA+R A A
Sbjct: 1938 KNVIRNV--HILLKQISGTDGEGNNVPSGDFSREWAEAQRMMRELRNRNFGKHLREAEAD 1995
Query: 1366 HRTEALMDAQKEDFNSKHMANQRALG---KLSAHTHTLSLTDINELVCGAPGDAPCATSP 1422
R L+ + + H L + S + + L+D+ + A A A
Sbjct: 1996 KRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQA--- 2052
Query: 1423 CGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRR 1482
NG + ALG +QR + E S+ S +
Sbjct: 2053 --------------------NGLNQENERALG-------AIQRQVKEINSLQSDFTKYLT 2085
Query: 1483 QASEAQQRAQAALDKANASRGQVEQ----ANQELQELIQSVKDFLNQEGADP--DSIEMV 1536
A + + AL S+ + E+ N+ QEL V++ G + E
Sbjct: 2086 TADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKH 2145
Query: 1537 ATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDARRARSW 1596
A + EL+ E+I+ A E VR D + ++ AE A A
Sbjct: 2146 ARSLQELA--KQLEEIKRNASG-DELVRCAVDAATAYENILNAIKAAEDAANRAASASES 2202
Query: 1597 A------EDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADT-RDTEQTLYQVQERMAGA 1649
A ED +KA+T+ + ++ + Q ++ V+ + +QTL V +
Sbjct: 2203 ALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVI 2262
Query: 1650 ERALSSA-----GERARQLDALLEALK-LKRAGNSLA---------ASTAEETAGSAQGR 1694
+ L++ G + +DA++ + K + R N + T E GR
Sbjct: 2263 DTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGR 2322
Query: 1695 AQEAEQLLRGPLGDQYQTVKALAE------RKAQGV---LAAQARAEQLRDEARDLLQAA 1745
Q + + L D +V L RK + + L D R+L+Q A
Sbjct: 2323 TQNED--FKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQA 2380
Query: 1746 QDKLQRL 1752
+D ++
Sbjct: 2381 RDAASKV 2387
Score = 88.6 bits (218), Expect = 5e-17
Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 25/155 (16%)
Query: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRR 469
C+C P G+ G C GQC C+ +V+G +C +C G +G C+
Sbjct: 1266 CECHPTGAT-GPHCSPE--------GGQCPCQPNVIGRQCTRCATGHYGFP-----RCKP 1311
Query: 470 CQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGA 529
C C R C+ +G C C C+ C H H + GC C+C G
Sbjct: 1312 CSCGRR-------LCEEMTGQCRCPPRTVRPQCEVC-ETHSFSFHPMAGCEGCNCSRRGT 1363
Query: 530 LD---PQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
++ P+CD +GQC C+ + GR+C++ G++R
Sbjct: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYR 1398
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/169 (31%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSG 436
C AG C+ C P +YRD V +C+ QDG SG
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG--------------SG 1701
Query: 437 QC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYC 493
C C+ + G C++C++G++G ++ CR C C + +T C N G C C
Sbjct: 1702 ICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSF--ATGCVVNGGDVRCSC 1757
Query: 494 KRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQC 541
K TG C+RC PG++G G C+PC C+ G L C TG C
Sbjct: 1758 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC 1805
Score = 77.4 bits (189), Expect = 1e-13
Identities = 49/132 (37%), Positives = 61/132 (46%), Gaps = 14/132 (10%)
Query: 748 QC--HEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCL 803
QC H EG S+ C L +L +G C+C+ G++S EC G C
Sbjct: 600 QCKLHVEGPTCSR------CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
Query: 804 CKPGVVGRRCDLCAPGYYGFGPT---GCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLR 860
CK V G CD C GY+ + GCQ CQC GALSS+C SG C CR G
Sbjct: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
Query: 861 CDRCQRGQWGFP 872
C R + + FP
Sbjct: 714 CQRPENNYY-FP 724
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 20/132 (15%)
Query: 438 CRCKEHVVGTRCQQCRDGFFGLSISDRLG-----CRRCQCNARGTVPGSTPCDPNSGSCY 492
C C G CQ C G++ D G C C CN S C SG C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICV 1704
Query: 493 -CKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDCDVGGALDPQC--DEGTGQCHCRQHMV 548
C+ G C+RC G++G + H CR C C + C + G +C C+
Sbjct: 1705 NCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 1762
Query: 549 GRRCEQVQPGYF 560
G +CE+ PGYF
Sbjct: 1763 GTQCERCAPGYF 1774
Score = 61.2 bits (147), Expect = 9e-09
Identities = 53/190 (27%), Positives = 80/190 (42%), Gaps = 46/190 (24%)
Query: 271 YYALYELVVRGNCF---CYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD 326
YY ++ + G C C GH+++C G C+ C+HNT G +CE+CQ+
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAGEHCERCQE 1720
Query: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV--SGGVCDGCQHNTAGR 384
Y + A G +CR C C HT+S A+G V G V C+ G
Sbjct: 1721 GY----YGNAVHG---SCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Query: 385 HCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHV 444
CE C P ++ +P K C+ C C+ G G C ++G C +E
Sbjct: 1765 QCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL--GSCHP--------LTGDCINQEPK 1811
Query: 445 VGTRCQQCRD 454
+ ++C D
Sbjct: 1812 DSSPAEECDD 1821
Score = 47.0 bits (110), Expect = 2e-04
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 37/124 (29%)
Query: 469 RCQCNARGTVPGSTPCDPNSGS----CYCKRLVTGRGCDRCLPGH---------WGLSHD 515
+C CN V C+ N+ C C+ G CDRC G+ W SH+
Sbjct: 298 QCVCNGHAEV-----CNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE 352
Query: 516 LLGCRPCDCDVGGA---LDPQCDE------------GTGQC-HCRQHMVGRRCEQVQPGY 559
C C+C + DP + G G C +C+ + G CEQ GY
Sbjct: 353 ---CEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 560 FRPF 563
+RP+
Sbjct: 410 YRPY 413
Score = 45.4 bits (106), Expect = 5e-04
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
G PC+C GA P C GQC C+ +++GR+C + G++
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
Score = 38.1 bits (87), Expect = 0.078
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 308 GACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRKCECHGHTHSCH 357
GAC+CK N G C C++ F+ D PA + C C C G + CH
Sbjct: 1422 GACLCKENVEGTECNVCREGSFHLD----PA---NLKGCTSCFCFGVNNQCH 1466
>gi|189217425 laminin alpha 3 subunit isoform 3 [Homo sapiens]
Length = 3277
Score = 257 bits (656), Expect = 8e-68
Identities = 201/701 (28%), Positives = 286/701 (40%), Gaps = 171/701 (24%)
Query: 1 MELTSRERGR--GQPLPWELRLGLLLSVLAATLAQAPAPDVPGCSRG-SCYPATGDLLVG 57
M +R RGR G LP L L+L VL A A A P G + G S +P +L
Sbjct: 1 MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDP---GAAAGLSLHPTYFNL--A 55
Query: 58 RADRLTASSTCGLNGP-----QP--YCIV---------SHLQDEKKCFLCDSRRPFSARD 101
A R+ A++TCG GP QP YC + H + C C+S P A
Sbjct: 56 EAARIWATATCGERGPGEGRPQPELYCKLVGGPTAPGSGHTIQGQFCDYCNSEDPRKA-- 113
Query: 102 NPHSHRIQNVVTSFAPQRRAAWWQSE-----NGIPAVTIQLDLEAEFHFTHLIMTFKTF- 155
H + N + WWQS V + LDL FH ++++ F
Sbjct: 114 ----HPVTNAIDG-----SERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSP 164
Query: 156 RPAAMLVERSADFGRTWHVYRYFSY---DCGADFPGVPLAPPRHWDDVVCESRYSEIEPS 212
RP ++ERS DFG T+ ++YF++ DC +F DDV+C + YS I P
Sbjct: 165 RPDLWVLERSVDFGSTYSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPL 224
Query: 213 TEGEVIYRVLDPAIPIPD-PYSSRIQNLLKITNLRVNLTRLHTLGDNLLDPRRE---IRE 268
GEV+ +++ + +S ++ K TN+R+ R +TL +L+ + +
Sbjct: 225 ENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLGHLISKAQRDPTVTR 284
Query: 269 KYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFY 328
+YYY++ ++ + G C C GHA C + E + C C+H+T G C++C Y
Sbjct: 285 RYYYSIKDISIGGQCVCNGHAEVCNIN-----NPEKLFR--CECQHHTCGETCDRCCTGY 337
Query: 329 RDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVS-------GGVCDGCQHNT 381
WRPA SH C C CHGH +C++D V +++ GGVC CQHNT
Sbjct: 338 NQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNT 397
Query: 382 AGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGS----QDGGRC-------------- 423
AG +CE C +YR + P C C CDP + Q GRC
Sbjct: 398 AGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKC 457
Query: 424 --------------------DSHDDPALGLVS-----------------GQCRCKEHVVG 446
S +DP G + G+C C+ V G
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEG 517
Query: 447 TRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCL 506
RC CR GF+ I C+ C C+A G+ PC +G C C+ VTG+ CDRCL
Sbjct: 518 PRCDTCRSGFYSFPI-----CQACWCSALGSY--QMPCSSVTGQCECRPGVTGQRCDRCL 570
Query: 507 PG--------------------------------------------HWGL-SHDLLGCRP 521
G +W L + GC
Sbjct: 571 SGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE 630
Query: 522 CDCDVGGALD--PQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
C C G + +C +G G CHC+ H+ G C+ + GYF
Sbjct: 631 CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYF 671
Score = 169 bits (428), Expect = 2e-41
Identities = 124/430 (28%), Positives = 171/430 (39%), Gaps = 110/430 (25%)
Query: 849 QCLCRTGAFGLRCDRCQRG----QWGFPS------CRPCVCNGHADEC------------ 886
+C C+ G CDRC G +W + C C C+GHA C
Sbjct: 318 RCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASNCYYDPDVERQQAS 377
Query: 887 -NTHT-----GACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQ--CRPCPC-PEGPGSQR 937
NT G C+ C+ +T G +CE+C G++ +P C PC C PE
Sbjct: 378 LNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPE------ 431
Query: 938 HFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDP----------SRPG------G 981
A C Q CHC+ + G CE CA G++ P S P G
Sbjct: 432 -HADGCEQGSGR----CHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAG 486
Query: 982 RCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCN 1041
+ C+C N++ + P+ CD H G+CL C EGP C C+ GF+ C C C+
Sbjct: 487 DIKGCDC--NLEGVLPEICDAH-GRCL-CRPGVEGPRCDTCRSGFYSFPI---CQACWCS 539
Query: 1042 LLGTNPQQCPSP---------------DQC--------HCDPSS-------------GQC 1065
LG+ C S D+C HC SS G C
Sbjct: 540 ALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYC 599
Query: 1066 PCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPT--CNEFTGQCHCRAGFG 1121
C +V+GP+C RC +WNL + GC C CH + T C + G CHC++ G
Sbjct: 600 QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCHCKSHVG 659
Query: 1122 GRTCSECQELHWG---DPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCAR 1178
G +C C++ ++ C C CD G + C +G C CR V G C +
Sbjct: 660 GDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPEN 719
Query: 1179 GFSGIFPACH 1188
+ FP H
Sbjct: 720 NY--YFPDLH 727
Score = 167 bits (424), Expect = 7e-41
Identities = 117/392 (29%), Positives = 167/392 (42%), Gaps = 113/392 (28%)
Query: 283 CFCYGHASECAPAPG-----APAHAEGMVHGA--CI-CKHNTRGLNCEQCQDFYRDLPWR 334
C C+GHAS C P A + +G+ G CI C+HNT G+NCEQC Y +R
Sbjct: 356 CNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY----YR 411
Query: 335 P------AEDG---------HSHACR----KCECHGHTH--SC--------HFDMAVYL- 364
P A DG H+ C +C C + H +C +F + +
Sbjct: 412 PYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIP 471
Query: 365 ------------ASGNVSG----------GVCDG-----CQHNTAGRHCELCRPFFYRDP 397
+G++ G +CD C+ G C+ CR FY P
Sbjct: 472 IFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFP 531
Query: 398 TKDLRDPAVCRSCDCDPMGSQD-----------------GGRCD---------------- 424
+C++C C +GS G RCD
Sbjct: 532 --------ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSS 583
Query: 425 SHDDPALGLVS--GQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGST 482
S DPA + S G C+CK HV G C +C+ ++ L + GC C+C+ GTV G+
Sbjct: 584 SACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGTVSGTG 643
Query: 483 PCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCRPCDCDVGGALDPQCDEGTGQC 541
C G C+CK V G CD C G++ L + GC+ C CD+GGAL C +G C
Sbjct: 644 ECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVC 703
Query: 542 HCRQHMVGRRCEQVQPGYFRPFLDHLIWEAED 573
CR+H+VG+ C++ + Y+ P L H+ +E ED
Sbjct: 704 QCREHVVGKVCQRPENNYYFPDLHHMKYEIED 735
Score = 149 bits (375), Expect = 3e-35
Identities = 107/363 (29%), Positives = 143/363 (39%), Gaps = 71/363 (19%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYYG-FG-----PTGCQACQCSHEGALSSLCEKTSGQCL 851
GG C+ C+ G C+ CA GYY +G P GC C C E A CE+ SG+C
Sbjct: 387 GGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADG--CEQGSGRCH 444
Query: 852 CRTGAFGLRCDRCQRGQWGFPSC---------------------RPCVCNGHA---DECN 887
C+ G C++C G + FP C + C CN + C+
Sbjct: 445 CKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICD 504
Query: 888 THTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDE 947
H G CL CR G C+ C +GF+ P C+ C C Q ++ Q
Sbjct: 505 AH-GRCL-CRPGVEGPRCDTCRSGFYSFP------ICQACWCSALGSYQMPCSSVTGQ-- 554
Query: 948 YSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDP-DACDPHTGQ 1006
C CR G TG RC+ C G + P C G+ DP + + G
Sbjct: 555 ------CECRPGVTGQRCDRCLSGAYDFP----------HCQGSSSACDPAGTINSNLGY 598
Query: 1007 CLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQ 1064
C +C H EGP C+ CK + + C C C+ GT C G
Sbjct: 599 C-QCKLHVEGPTCSRCKLLYWNLDKENPSGCSECKCHKAGT------VSGTGECRQGDGD 651
Query: 1065 CPCLPNVQGPSCDRCAPNFWNLTSGH--GCQPCACHPSRARGPTCNEFTGQCHCRAGFGG 1122
C C +V G SCD C ++ L + GCQ C C A C+ +G C CR G
Sbjct: 652 CHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVG 711
Query: 1123 RTC 1125
+ C
Sbjct: 712 KVC 714
Score = 147 bits (370), Expect = 1e-34
Identities = 101/343 (29%), Positives = 138/343 (40%), Gaps = 71/343 (20%)
Query: 877 CVCNGHADECNTHTGACL---GCRDHTGGEHCERCIAGFHGDPRLP----YGGQCRPCPC 929
CVCNGHA+ CN + L C+ HT GE C+RC G++ P +C C C
Sbjct: 299 CVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNC 358
Query: 930 PE-------GPGSQRHFATSCHQDEYSQQIVC-HCRAGYTGLRCEACAPGHF---GDPSR 978
P +R A+ Q Y+ VC +C+ G+ CE CA G++ G P
Sbjct: 359 HGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVD 418
Query: 979 PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRC 1038
C C C DP D C+ +G+C HCKP FHG +C +C
Sbjct: 419 APDGCIPCSC----DPEHADGCEQGSGRC-------------HCKPNFHGD----NCEKC 457
Query: 1039 T--------CNLLGTNPQQCPSPDQ--------CHCD---------PSSGQCPCLPNVQG 1073
C + P PS + C C+ + G+C C P V+G
Sbjct: 458 AIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEG 517
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHW 1133
P CD C F++ CQ C C + C+ TGQC CR G G+ C C +
Sbjct: 518 PRCDTCRSGFYSFPI---CQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAY 574
Query: 1134 GDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQC 1176
P Q + CD G + G+C C+ V G C +C
Sbjct: 575 DFPHCQGSSSACDPAG----TINSNLGYCQCKLHVEGPTCSRC 613
Score = 141 bits (356), Expect = 5e-33
Identities = 95/332 (28%), Positives = 134/332 (40%), Gaps = 55/332 (16%)
Query: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF------------GP 825
+G +PC C+P+ + C G+C CKP G C+ CA GYY F P
Sbjct: 421 DGCIPCSCDPEHA--DGCEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFPVSTP 478
Query: 826 TG-------CQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCV 878
+ + C C+ EG L +C+ G+CLCR G G RCD C+ G + FP C+ C
Sbjct: 479 SSEDPVAGDIKGCDCNLEGVLPEICD-AHGRCLCRPGVEGPRCDTCRSGFYSFPICQACW 537
Query: 879 CN---GHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
C+ + C++ TG C CR G+ C+RC++G + P G C P G +
Sbjct: 538 CSALGSYQMPCSSVTGQC-ECRPGVTGQRCDRCLSGAYDFPHCQ--GSSSACD-PAGTIN 593
Query: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFG-DPSRPGGRCQLCECSGNIDP 994
S C C+ G C C ++ D P G C C+C
Sbjct: 594 -------------SNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSG-CSECKCHKAGTV 639
Query: 995 MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHG--QAARQSCHRCTCNLLGTNPQQCPS 1052
C G C C H G C C+ G+ ++ C C C++ G C
Sbjct: 640 SGTGECRQGDGDC-HCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSG 698
Query: 1053 PDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFW 1084
P SG C C +V G C R N++
Sbjct: 699 P--------SGVCQCREHVVGKVCQRPENNYY 722
Score = 140 bits (353), Expect = 1e-32
Identities = 73/207 (35%), Positives = 98/207 (47%), Gaps = 54/207 (26%)
Query: 802 CLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRC 861
C C P G C C+PGYY H+G + G+C+
Sbjct: 1654 CACPPAYAGDSCQGCSPGYYR-----------DHKGLYT-------GRCV---------- 1685
Query: 862 DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYG 921
PC CNGH+++C +G C+ C+ +T GEHCERC G++G+
Sbjct: 1686 --------------PCNCNGHSNQCQDGSGICVNCQHNTAGEHCERCQEGYYGNA---VH 1728
Query: 922 GQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG 981
G CR CPCP FAT C + + C C+AGYTG +CE CAPG+FG+P + GG
Sbjct: 1729 GSCRACPCPH----TNSFATGCVVN--GGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
Query: 982 RCQLCECSGNIDPMDPDACDPHTGQCL 1008
CQ C C+ N +C P TG C+
Sbjct: 1783 SCQPCSCNSN---GQLGSCHPLTGDCI 1806
Score = 136 bits (342), Expect = 2e-31
Identities = 76/230 (33%), Positives = 99/230 (43%), Gaps = 52/230 (22%)
Query: 749 CHEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGV 808
C + + S C SL + GALPC+C+P G+ C+P GGQC C+P V
Sbjct: 1232 CGKNSFYLDPQTASRFCKNSARSLVAFYHKGALPCECHPTGATGPHCSPEGGQCPCQPNV 1291
Query: 809 VGRRCDLCAPGYYGF------------------------------------------GPT 826
+GR+C CA G+YGF
Sbjct: 1292 IGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMA 1351
Query: 827 GCQACQCSHEGALSSL---CEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHA 883
GC+ C CS G + + C++ SGQC C+ G +CDRC G + FP C PC CN
Sbjct: 1352 GCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDG 1411
Query: 884 DE---CNTHTGACLGCRDHTGGEHCERCIAG-FHGDPRLPYGGQCRPCPC 929
E C+ TGACL C+++ G C C G FH DP G C C C
Sbjct: 1412 TEPGVCDPGTGACL-CKENVEGTECNVCREGSFHLDPANLKG--CTSCFC 1458
Score = 115 bits (289), Expect = 3e-25
Identities = 78/289 (26%), Positives = 111/289 (38%), Gaps = 55/289 (19%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGG-----RCQLCECSGNIDP 994
A C+ + + C C+ G C+ C G+ RP C+ C C G+
Sbjct: 305 AEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHGHASN 364
Query: 995 M--DPDACDPHT-----------GQCLRCLHHTEGPHCAHCKPGFHGQA-----ARQSCH 1036
DPD G C+ C H+T G +C C G++ A C
Sbjct: 365 CYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCI 424
Query: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTS-------- 1088
C+C+ P+ C+ SG+C C PN G +C++CA ++N
Sbjct: 425 PCSCD-----PEHADG-----CEQGSGRCHCKPNFHGDNCEKCAIGYYNFPFCLRIPIFP 474
Query: 1089 ----------GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGL 1138
+ C C+ C+ G+C CR G G C C+ + P
Sbjct: 475 VSTPSSEDPVAGDIKGCDCNLEGVLPEICDAH-GRCLCRPGVEGPRCDTCRSGFYSFP-- 531
Query: 1139 QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPAC 1187
C AC C + G C TG C CRPGV+G RCD+C G + FP C
Sbjct: 532 ICQACWCSALGSYQMPCSSVTGQCECRPGVTGQRCDRCLSG-AYDFPHC 579
Score = 115 bits (288), Expect = 4e-25
Identities = 67/193 (34%), Positives = 86/193 (44%), Gaps = 34/193 (17%)
Query: 371 GGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGR--CDSHDD 428
GG C CQ N GR C C Y P C+ C C GR C+
Sbjct: 1282 GGQCP-CQPNVIGRQCTRCATGHYGFPR--------CKPCSC--------GRRLCEE--- 1321
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP-CDPN 487
++GQCRC V +C+ C F S GC C C+ RGT+ + P CD +
Sbjct: 1322 -----MTGQCRCPPRTVRPQCEVCETHSF--SFHPMAGCEGCNCSRRGTIEAAMPECDRD 1374
Query: 488 SGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHM 547
SG C CK +TGR CDRC G + C PC+C+ G CD GTG C C++++
Sbjct: 1375 SGQCRCKPRITGRQCDRCASGFYRFPE----CVPCNCNRDGTEPGVCDPGTGACLCKENV 1430
Query: 548 VGRRCEQVQPGYF 560
G C + G F
Sbjct: 1431 EGTECNVCREGSF 1443
Score = 110 bits (276), Expect = 9e-24
Identities = 55/181 (30%), Positives = 81/181 (44%), Gaps = 15/181 (8%)
Query: 953 VCHCRAGYTGLRCEACAPGHFGD-PSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
+C C Y G C+ C+PG++ D GRC C C+G+ + C +G C+ C
Sbjct: 1653 ICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICVNCQ 1707
Query: 1012 HHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
H+T G HC C+ G++G A SC C C P C + +C C
Sbjct: 1708 HNTAGEHCERCQEGYYGNAVHGSCRACPC------PHTNSFATGCVVNGGDVRCSCKAGY 1761
Query: 1072 QGPSCDRCAPNFWNLTS--GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQ 1129
G C+RCAP ++ G CQPC+C+ + G +C+ TG C + EC
Sbjct: 1762 TGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDCINQEPKDSSPAEECD 1820
Query: 1130 E 1130
+
Sbjct: 1821 D 1821
Score = 109 bits (272), Expect = 3e-23
Identities = 54/139 (38%), Positives = 68/139 (48%), Gaps = 13/139 (9%)
Query: 1057 HCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHC 1116
HC P GQCPC PNV G C RCA + C+PC+C C E TGQC C
Sbjct: 1277 HCSPEGGQCPCQPNVIGRQCTRCATGHYGFPR---CKPCSCGRR-----LCEEMTGQCRC 1328
Query: 1117 RAGFGGRTCSECQELHWG-DPGLQCHACDCDSRG---IDTPQCHRFTGHCSCRPGVSGVR 1172
C C+ + P C C+C RG P+C R +G C C+P ++G +
Sbjct: 1329 PPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQ 1388
Query: 1173 CDQCARGFSGIFPACHPCH 1191
CD+CA GF FP C PC+
Sbjct: 1389 CDRCASGFYR-FPECVPCN 1406
Score = 102 bits (253), Expect = 4e-21
Identities = 65/219 (29%), Positives = 88/219 (40%), Gaps = 33/219 (15%)
Query: 986 CEC--SGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLL 1043
CEC +G P C P GQC C + G C C G +G C C+C
Sbjct: 1266 CECHPTGATGPH----CSPEGGQC-PCQPNVIGRQCTRCATGHYGFPR---CKPCSCG-- 1315
Query: 1044 GTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPS--- 1100
+ C+ +GQC C P P C+ C + ++ GC+ C C
Sbjct: 1316 -----------RRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPMAGCEGCNCSRRGTI 1364
Query: 1101 RARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCHRFTG 1160
A P C+ +GQC C+ GR C C + P +C C+C+ G + C TG
Sbjct: 1365 EAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFP--ECVPCNCNRDGTEPGVCDPGTG 1422
Query: 1161 HCSCRPGVSGVRCDQCARGFSGIFPA----CHPCHACFG 1195
C C+ V G C+ C G + PA C C CFG
Sbjct: 1423 ACLCKENVEGTECNVCREGSFHLDPANLKGCTSCF-CFG 1460
Score = 95.5 bits (236), Expect = 4e-19
Identities = 71/237 (29%), Positives = 91/237 (38%), Gaps = 48/237 (20%)
Query: 291 ECAP--APGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCE 348
EC P A G EG G C C+ N G C +C + P C+ C
Sbjct: 1267 ECHPTGATGPHCSPEG---GQCPCQPNVIGRQCTRCATGHYGFP----------RCKPCS 1313
Query: 349 CHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCR 408
C C +M G C C T CE+C + A C
Sbjct: 1314 CGRRL--CE-EMT----------GQCR-CPPRTVRPQCEVCETHSF-----SFHPMAGCE 1354
Query: 409 SCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
C+C G+ + + D SGQCRCK + G +C +C GF+ C
Sbjct: 1355 GCNCSRRGTIEAAMPECDRD------SGQCRCKPRITGRQCDRCASGFYRFP-----ECV 1403
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDC 524
C CN GT PG CDP +G+C CK V G C+ C G + L +L GC C C
Sbjct: 1404 PCNCNRDGTEPGV--CDPGTGACLCKENVEGTECNVCREGSFHLDPANLKGCTSCFC 1458
Score = 94.7 bits (234), Expect = 7e-19
Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 17/160 (10%)
Query: 763 EACAPLLISLSTLIYNG-ALPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGY 820
+ C+P +Y G +PC CN S++C G C+ C+ G C+ C GY
Sbjct: 1666 QGCSPGYYRDHKGLYTGRCVPCNCNGH---SNQCQDGSGICVNCQHNTAGEHCERCQEGY 1722
Query: 821 YGFGPTG-CQACQCSHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP----- 872
YG G C+AC C H + ++ C G +C C+ G G +C+RC G +G P
Sbjct: 1723 YGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGG 1782
Query: 873 SCRPCVC--NGHADECNTHTGACLG--CRDHTGGEHCERC 908
SC+PC C NG C+ TG C+ +D + E C+ C
Sbjct: 1783 SCQPCSCNSNGQLGSCHPLTGDCINQEPKDSSPAEECDDC 1822
Score = 93.2 bits (230), Expect = 2e-18
Identities = 55/182 (30%), Positives = 79/182 (43%), Gaps = 30/182 (16%)
Query: 310 CICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV 369
C C G +C+ C Y +R + ++ C C C+GH++ C
Sbjct: 1654 CACPPAYAGDSCQGCSPGY----YRDHKGLYTGRCVPCNCNGHSNQCQD----------- 1698
Query: 370 SGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDP 429
G+C CQHNTAG HCE C+ +Y + CR+C C S G + D
Sbjct: 1699 GSGICVNCQHNTAGEHCERCQEGYYGNAVH-----GSCRACPCPHTNSFATGCVVNGGDV 1753
Query: 430 ALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSG 489
+C CK GT+C++C G+FG C+ C CN+ G + GS C P +G
Sbjct: 1754 -------RCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQL-GS--CHPLTG 1803
Query: 490 SC 491
C
Sbjct: 1804 DC 1805
Score = 88.6 bits (218), Expect = 5e-17
Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 25/155 (16%)
Query: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRR 469
C+C P G+ G C GQC C+ +V+G +C +C G +G C+
Sbjct: 1266 CECHPTGAT-GPHCSPE--------GGQCPCQPNVIGRQCTRCATGHYGFP-----RCKP 1311
Query: 470 CQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGA 529
C C R C+ +G C C C+ C H H + GC C+C G
Sbjct: 1312 CSCGRR-------LCEEMTGQCRCPPRTVRPQCEVC-ETHSFSFHPMAGCEGCNCSRRGT 1363
Query: 530 LD---PQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
++ P+CD +GQC C+ + GR+C++ G++R
Sbjct: 1364 IEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYR 1398
Score = 85.5 bits (210), Expect = 4e-16
Identities = 150/761 (19%), Positives = 280/761 (36%), Gaps = 115/761 (15%)
Query: 1016 GPHCAHCKPGFHGQAARQSCHRCT-CNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQG 1073
G C C PG++ RC CN G + Q C SG C C N G
Sbjct: 1662 GDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQ---------CQDGSGICVNCQHNTAG 1712
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSR--ARGPTCNEFTGQCHCRAGFGGRTCSECQEL 1131
C+RC ++ C+ C C + A G N +C C+AG+ G C C
Sbjct: 1713 EHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPG 1772
Query: 1132 HWGDP---GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACH 1188
++G+P G C C C+S G CH TG C + ++ C
Sbjct: 1773 YFGNPQKFGGSCQPCSCNSNG-QLGSCHPLTGDCINQEPKDSSPAEE-----------CD 1820
Query: 1189 PCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFESSFWHMQEKLGIVQGIVGAR 1248
C +C ++ DLA ++L +LQ HM+ + ++ +
Sbjct: 1821 DCDSCV---MTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNY 1877
Query: 1249 NTSAASTAQLVEATEELRREIGEATEHLTQ-LEADLTDVQDENFNANHALSGLERDRLAL 1307
++ ++ +E E ++ + E L + + + Q N N N A
Sbjct: 1878 RSAISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQ--------- 1928
Query: 1308 NLTLRQLDQHL-DLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARH 1366
+ ++LD + +++++ + L + + H E AN+ ++ + + R
Sbjct: 1929 --SAKELDVKIKNVIRNVHMLNRIRTWQKTH--QGENNGLANSIRDSLNEYEAKLSDLRA 1984
Query: 1367 RTEALMDAQKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGA 1426
R + AQ + N + N+RALG + + +IN L
Sbjct: 1985 RLQEAA-AQAKQANGLNQENERALGAIQR-----QVKEINSLQS---------------- 2022
Query: 1427 GCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSILSRVAETRRQASE 1486
TAD +L + ++++ E + + + E R++ S+
Sbjct: 2023 --------------DFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSD 2068
Query: 1487 AQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIP 1546
+ + K + + E+ + LQEL + +++ D E+V V
Sbjct: 2069 KVRELSRSAGKTSLVE-EAEKHARSLQELAKQLEEIKRNASGD----ELVRCAV---DAA 2120
Query: 1547 ASAEQIQHLAGAIAERVRSLADVDAILARTV--GDV-RRAEQLLQDARRARSWAE-DEKQ 1602
+ E I + A + A +TV D+ R+A+ L ++ + + A+ +K+
Sbjct: 2121 TAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKK 2180
Query: 1603 KAETVQAALEEAQRAQGIAQGAIRGAVADTRDT--EQTLYQVQERMAGAERALSSAGERA 1660
+ V AL Q+ I ++ V DT T L+ +Q + +SSA
Sbjct: 2181 LKQEVSPALNNLQQTLNIV--TVQKEVIDTNLTTLRDGLHGIQR--GDIDAMISSAKSMV 2236
Query: 1661 RQ----LDALLEALK-----LKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQ 1711
R+ D +L+ L ++R ++ T E A A + L L D ++
Sbjct: 2237 RKANDITDEVLDGLNPIQTDVERIKDTY-GRTQNEDFKKALTDADNSVNKLTNKLPDLWR 2295
Query: 1712 TVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRL 1752
++++ ++ L D R+L+Q A+D ++
Sbjct: 2296 KIESINQQ-----LLPLGNISDNMDRIRELIQQARDAASKV 2331
Score = 81.6 bits (200), Expect = 6e-15
Identities = 53/169 (31%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 377 CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSG 436
C AG C+ C P +YRD V +C+ QDG SG
Sbjct: 1656 CPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG--------------SG 1701
Query: 437 QC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGS--CYC 493
C C+ + G C++C++G++G ++ CR C C + +T C N G C C
Sbjct: 1702 ICVNCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSF--ATGCVVNGGDVRCSC 1757
Query: 494 KRLVTGRGCDRCLPGHWGLSHDLLG-CRPCDCDVGGALDPQCDEGTGQC 541
K TG C+RC PG++G G C+PC C+ G L C TG C
Sbjct: 1758 KAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLG-SCHPLTGDC 1805
Score = 77.4 bits (189), Expect = 1e-13
Identities = 49/132 (37%), Positives = 61/132 (46%), Gaps = 14/132 (10%)
Query: 748 QC--HEEGLVPSKTSPSEACAPLLISLSTLIYNGALPCQCNPQGSLSS--ECNPHGGQCL 803
QC H EG S+ C L +L +G C+C+ G++S EC G C
Sbjct: 600 QCKLHVEGPTCSR------CKLLYWNLDKENPSGCSECKCHKAGTVSGTGECRQGDGDCH 653
Query: 804 CKPGVVGRRCDLCAPGYYGFGPT---GCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLR 860
CK V G CD C GY+ + GCQ CQC GALSS+C SG C CR G
Sbjct: 654 CKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKV 713
Query: 861 CDRCQRGQWGFP 872
C R + + FP
Sbjct: 714 CQRPENNYY-FP 724
Score = 65.9 bits (159), Expect = 3e-10
Identities = 41/132 (31%), Positives = 54/132 (40%), Gaps = 20/132 (15%)
Query: 438 CRCKEHVVGTRCQQCRDGFFGLSISDRLG-----CRRCQCNARGTVPGSTPCDPNSGSCY 492
C C G CQ C G++ D G C C CN S C SG C
Sbjct: 1654 CACPPAYAGDSCQGCSPGYY----RDHKGLYTGRCVPCNCNGH-----SNQCQDGSGICV 1704
Query: 493 -CKRLVTGRGCDRCLPGHWGLS-HDLLGCRPCDCDVGGALDPQC--DEGTGQCHCRQHMV 548
C+ G C+RC G++G + H CR C C + C + G +C C+
Sbjct: 1705 NCQHNTAGEHCERCQEGYYGNAVHG--SCRACPCPHTNSFATGCVVNGGDVRCSCKAGYT 1762
Query: 549 GRRCEQVQPGYF 560
G +CE+ PGYF
Sbjct: 1763 GTQCERCAPGYF 1774
Score = 61.2 bits (147), Expect = 9e-09
Identities = 53/190 (27%), Positives = 80/190 (42%), Gaps = 46/190 (24%)
Query: 271 YYALYELVVRGNCF---CYGHASECAPAPGAPAHAEGMVHGACI-CKHNTRGLNCEQCQD 326
YY ++ + G C C GH+++C G C+ C+HNT G +CE+CQ+
Sbjct: 1672 YYRDHKGLYTGRCVPCNCNGHSNQCQDG-----------SGICVNCQHNTAGEHCERCQE 1720
Query: 327 FYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNV--SGGVCDGCQHNTAGR 384
Y + A G +CR C C HT+S A+G V G V C+ G
Sbjct: 1721 GY----YGNAVHG---SCRACPC-PHTNS--------FATGCVVNGGDVRCSCKAGYTGT 1764
Query: 385 HCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHV 444
CE C P ++ +P K C+ C C+ G G C ++G C +E
Sbjct: 1765 QCERCAPGYFGNPQK---FGGSCQPCSCNSNGQL--GSCHP--------LTGDCINQEPK 1811
Query: 445 VGTRCQQCRD 454
+ ++C D
Sbjct: 1812 DSSPAEECDD 1821
Score = 47.0 bits (110), Expect = 2e-04
Identities = 34/124 (27%), Positives = 48/124 (38%), Gaps = 37/124 (29%)
Query: 469 RCQCNARGTVPGSTPCDPNSGS----CYCKRLVTGRGCDRCLPGH---------WGLSHD 515
+C CN V C+ N+ C C+ G CDRC G+ W SH+
Sbjct: 298 QCVCNGHAEV-----CNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHE 352
Query: 516 LLGCRPCDCDVGGA---LDPQCDE------------GTGQC-HCRQHMVGRRCEQVQPGY 559
C C+C + DP + G G C +C+ + G CEQ GY
Sbjct: 353 ---CEACNCHGHASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGY 409
Query: 560 FRPF 563
+RP+
Sbjct: 410 YRPY 413
Score = 45.4 bits (106), Expect = 5e-04
Identities = 16/43 (37%), Positives = 25/43 (58%)
Query: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
G PC+C GA P C GQC C+ +++GR+C + G++
Sbjct: 1262 GALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHY 1304
Score = 38.1 bits (87), Expect = 0.078
Identities = 19/52 (36%), Positives = 25/52 (48%), Gaps = 9/52 (17%)
Query: 308 GACICKHNTRGLNCEQCQD--FYRDLPWRPAEDGHSHACRKCECHGHTHSCH 357
GAC+CK N G C C++ F+ D PA + C C C G + CH
Sbjct: 1422 GACLCKENVEGTECNVCREGSFHLD----PA---NLKGCTSCFCFGVNNQCH 1466
Score = 31.6 bits (70), Expect = 7.3
Identities = 39/164 (23%), Positives = 63/164 (38%), Gaps = 19/164 (11%)
Query: 1618 QGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALL-------EAL 1670
QG++ A G + R E ++ ++ A+S+ G + L+ L E L
Sbjct: 1848 QGLSASA--GLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEGLERELTDLNQEFETL 1905
Query: 1671 KLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKA-QGVLAAQA 1729
+ K NS A T A A+E + ++ + + + + +K QG
Sbjct: 1906 QEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQG--ENNG 1963
Query: 1730 RAEQLRDEARDLLQAAQDKLQRLQEL-------EGTYEENERAL 1766
A +RD + D RLQE G +ENERAL
Sbjct: 1964 LANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERAL 2007
>gi|148613884 netrin 1 [Homo sapiens]
Length = 604
Score = 247 bits (630), Expect = 8e-65
Identities = 160/486 (32%), Positives = 238/486 (48%), Gaps = 39/486 (8%)
Query: 18 LRLGLLLSVLAATLAQA-PAPDVPGCSRGSCYPATGDLLVGRADRLTASSTCGLNGPQPY 76
+R G LS+ A AQ P D G R C P + G+ R+ SSTCG P Y
Sbjct: 22 VRGGPGLSMFAGQAAQPDPCSDENGHPR-RCIPDFVNAAFGKDVRV--SSTCG-RPPARY 77
Query: 77 CIVSHLQDEK--KCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQSENGIPA-- 132
C+VS +E+ C LC++ P A + N WQSEN +
Sbjct: 78 CVVSERGEERLRSCHLCNASDPKKAHPPAFLTDLNN-------PHNLTCWQSENYLQFPH 130
Query: 133 -VTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCGADFPGVPL 191
VT+ L L +F T++ + F + RP +M + +S D+GRTW ++++S C +
Sbjct: 131 NVTLTLSLGKKFEVTYVSLQFCSPRPESMAIYKSMDYGRTWVPFQFYSTQCRKMYNRPHR 190
Query: 192 AP--PRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRI-QNLLKITNLRVN 248
AP ++ + VC ++++ P + G + + LD D +S + Q+ + T++RV
Sbjct: 191 APITKQNEQEAVCTDSHTDMRPLSGGLIAFSTLDGRPSAHDFDNSPVLQDWVTATDIRVA 250
Query: 249 LTRLHTLGDNLLDPRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHG 308
+RLHT GD D R+ Y+YA+ +L V G C C GHA+ C + +V
Sbjct: 251 FSRLHTFGDENEDDSELARDSYFYAVSDLQVGGRCKCNGHAARCVRD-----RDDSLV-- 303
Query: 309 ACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGN 368
C C+HNT G C++C+ F+ D PW+ A ++ C C C+ H C F+M +Y SG
Sbjct: 304 -CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGR 362
Query: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428
SGGVC C+HNTAGRHC C+ +YRD K + C++CDC P+G+ G C+
Sbjct: 363 KSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAA-GKTCNQ--- 418
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
+GQC CK+ V G C +C G + S S C + A T S+ +P
Sbjct: 419 -----TTGQCPCKDGVTGITCNRCAKG-YQQSRSPIAPCIKIPV-APPTTAASSVEEPED 471
Query: 489 GSCYCK 494
YCK
Sbjct: 472 CDSYCK 477
Score = 84.7 bits (208), Expect = 7e-16
Identities = 53/171 (30%), Positives = 71/171 (41%), Gaps = 37/171 (21%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLR---------CLHHTEGPHCAHCKPGFHGQ- 1029
GGRC+ C+ H +C+R C H+T GP C CKP + +
Sbjct: 282 GGRCK---------------CNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRP 326
Query: 1030 ----AARQS--CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC-PCLPNVQGPSCDRCAPN 1082
AR++ C C CNL + + S G C C N G C C
Sbjct: 327 WQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEG 386
Query: 1083 FWN-----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128
++ +T C+ C CHP A G TCN+ TGQC C+ G G TC+ C
Sbjct: 387 YYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRC 437
Score = 84.0 bits (206), Expect = 1e-15
Identities = 51/183 (27%), Positives = 75/183 (40%), Gaps = 25/183 (13%)
Query: 912 FHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG 971
F+ L GG+C+ C A C +D +VC CR G C+ C P
Sbjct: 273 FYAVSDLQVGGRCK---C-------NGHAARCVRDR-DDSLVCDCRHNTAGPECDRCKPF 321
Query: 972 HFGDP-----SRPGGRCQLCECSGNID------PMDPDACDPHTGQCLRCLHHTEGPHCA 1020
H+ P +R C C C+ + + + G CL C H+T G HC
Sbjct: 322 HYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCH 381
Query: 1021 HCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCA 1080
+CK G++ + HR C +P C+ ++GQCPC V G +C+RCA
Sbjct: 382 YCKEGYYRDMGKPITHRKACKACDCHPVGAAGKT---CNQTTGQCPCKDGVTGITCNRCA 438
Query: 1081 PNF 1083
+
Sbjct: 439 KGY 441
Score = 80.9 bits (198), Expect = 1e-14
Identities = 47/148 (31%), Positives = 65/148 (43%), Gaps = 22/148 (14%)
Query: 1065 CPCLPNVQGPSCDRCAPNFWN-------LTSGHGCQPCAC--HPSRARGP------TCNE 1109
C C N GP CDRC P ++ + C C C H R R + +
Sbjct: 304 CDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCNLHARRCRFNMELYKLSGRK 363
Query: 1110 FTGQC-HCRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGIDTPQCHRFTGHC 1162
G C +CR GR C C+E ++ D G C ACDC G C++ TG C
Sbjct: 364 SGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQC 423
Query: 1163 SCRPGVSGVRCDQCARGFSGIFPACHPC 1190
C+ GV+G+ C++CA+G+ PC
Sbjct: 424 PCKDGVTGITCNRCAKGYQQSRSPIAPC 451
Score = 75.1 bits (183), Expect = 6e-13
Identities = 49/166 (29%), Positives = 65/166 (39%), Gaps = 33/166 (19%)
Query: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP----------SCRPCVCN 880
C+C+ A S C CR G CDRC+ + P C C CN
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 881 GHADECNTHT-----------GACLGCRDHTGGEHCERCIAGFHGDPRLP--YGGQCRPC 927
HA C + G CL CR +T G HC C G++ D P + C+ C
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 928 PC-PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
C P G + +C+Q C C+ G TG+ C CA G+
Sbjct: 405 DCHPVGAAGK-----TCNQTTGQ----CPCKDGVTGITCNRCAKGY 441
Score = 67.4 bits (163), Expect = 1e-10
Identities = 35/88 (39%), Positives = 44/88 (50%), Gaps = 8/88 (9%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYY---GFGPT---GCQACQCSHEGALSSLCEKTSGQCL 851
GG CL C+ GR C C GYY G T C+AC C GA C +T+GQC
Sbjct: 365 GGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKACDCHPVGAAGKTCNQTTGQCP 424
Query: 852 CRTGAFGLRCDRCQRG-QWGFPSCRPCV 878
C+ G G+ C+RC +G Q PC+
Sbjct: 425 CKDGVTGITCNRCAKGYQQSRSPIAPCI 452
Score = 57.0 bits (136), Expect = 2e-07
Identities = 42/168 (25%), Positives = 63/168 (37%), Gaps = 32/168 (19%)
Query: 418 QDGGRCDSHDDPALGLVSGQ----CRCKEHVVGTRCQQCRDGFFG-----LSISDRLGCR 468
Q GGRC + A + C C+ + G C +C+ + + + C
Sbjct: 280 QVGGRCKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECV 339
Query: 469 RCQCNARGTVPGSTPCDPN-----------SGSCY-CKRLVTGRGCDRCLPGHWG----- 511
C CN + C N G C C+ GR C C G++
Sbjct: 340 ACNCNLH-----ARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKP 394
Query: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
++H C+ CDC GA C++ TGQC C+ + G C + GY
Sbjct: 395 ITHRK-ACKACDCHPVGAAGKTCNQTTGQCPCKDGVTGITCNRCAKGY 441
Score = 55.8 bits (133), Expect = 4e-07
Identities = 46/158 (29%), Positives = 60/158 (37%), Gaps = 29/158 (18%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYY--------GFGPTGCQACQCS 834
C+CN + C C+ G CD C P +Y C AC C+
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 835 HEG-------ALSSLC-EKTSGQCL-CRTGAFGLRCDRCQRGQW---GFP-----SCRPC 877
L L K+ G CL CR G C C+ G + G P +C+ C
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGYYRDMGKPITHRKACKAC 404
Query: 878 VCN--GHADE-CNTHTGACLGCRDHTGGEHCERCIAGF 912
C+ G A + CN TG C C+D G C RC G+
Sbjct: 405 DCHPVGAAGKTCNQTTGQC-PCKDGVTGITCNRCAKGY 441
Score = 43.9 bits (102), Expect = 0.001
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 24/127 (18%)
Query: 453 RDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHW-- 510
RD +F ++SD RC+CN G +S C C+ G CDRC P H+
Sbjct: 269 RDSYF-YAVSDLQVGGRCKCN--GHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDR 325
Query: 511 ----GLSHDLLGCRPCDCDVGGALDPQCD-----------EGTGQC-HCRQHMVGRRCEQ 554
+ + C C+C++ +C + G C +CR + GR C
Sbjct: 326 PWQRATAREANECVACNCNLHAR---RCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHY 382
Query: 555 VQPGYFR 561
+ GY+R
Sbjct: 383 CKEGYYR 389
Score = 37.7 bits (86), Expect = 0.10
Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 17/103 (16%)
Query: 1095 CACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDP--------GLQCHACDCD 1146
C C+ AR + + C CR G C C+ H+ P +C AC+C+
Sbjct: 285 CKCNGHAARCVRDRDDSLVCDCRHNTAGPECDRCKPFHYDRPWQRATAREANECVACNCN 344
Query: 1147 ---SRGIDTPQCHRFTGHCS------CRPGVSGVRCDQCARGF 1180
R + ++ +G S CR +G C C G+
Sbjct: 345 LHARRCRFNMELYKLSGRKSGGVCLNCRHNTAGRHCHYCKEGY 387
>gi|5453810 netrin 3 [Homo sapiens]
Length = 580
Score = 227 bits (579), Expect = 7e-59
Identities = 166/496 (33%), Positives = 223/496 (44%), Gaps = 70/496 (14%)
Query: 15 PWELRLGLLLSVLAATLAQAPAPDVP--------GCSRGSCYPATGDLLVGRADRLTASS 66
PW GLLL+ A +P P P G RG C P + +GR + ASS
Sbjct: 5 PW----GLLLTAGTLFAALSPGPPAPADPCHDEGGAPRG-CVPGLVNAALGR--EVLASS 57
Query: 67 TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPHSHRIQNVVTSFAPQRRAAWWQS 126
TCG + C D RR S ++TS W+S
Sbjct: 58 TCGRPAT------------RACDASDPRRAHSPA----------LLTSPGGTASPLCWRS 95
Query: 127 ENGIPA---VTIQLDLEAEFHFTHLIMTFKTFRPAAMLVERSADFGRTWHVYRYFSYDCG 183
E+ A VT+ + L F + + F + PA++ + +S D GR+W +FS C
Sbjct: 96 ESLPRAPLNVTLTVPLGKAFELVFVSLRFCSAPPASVALLKSQDHGRSWAPLGFFSSHCD 155
Query: 184 ADFPGVPL---APPRHWDDVVCESRYSEIEPSTEGEVIYRVLDPAIPIPDPYSSRI-QNL 239
D+ +P P + +C +P G + + + D + P D SS + Q+
Sbjct: 156 LDYGRLPAPANGPAGPGPEALCFPA-PLAQPDGSGLLAFSMQDSSPPGLDLDSSPVLQDW 214
Query: 240 LKITNLRVNLTRLHTLGDNLLDPR-REIREKYYYALYELVVRGNCFCYGHASECAPAPGA 298
+ T++RV LTR T GD PR E Y YA +L V G C C GHAS C
Sbjct: 215 VTATDVRVVLTRPSTAGD----PRDMEAVVPYSYAATDLQVGGRCKCNGHASRCL----- 265
Query: 299 PAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHF 358
+ H C C+H T G +C +C+ FY D PW+ A SHAC C C+GH C F
Sbjct: 266 ---LDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRF 322
Query: 359 DMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQ 418
+M +Y SG SGGVC C+HNTAGRHC CR FYRDP + L D CR+CDC P+G+
Sbjct: 323 NMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAA 382
Query: 419 DGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTV 478
G C+ +GQC CK+ V G C +C G F S S C + G
Sbjct: 383 -GKTCNQ--------TTGQCPCKDGVTGLTCNRCAPG-FQQSRSPVAPC--VKTPIPGPT 430
Query: 479 PGSTPCDPNSGSCYCK 494
S+P P +CK
Sbjct: 431 EDSSPVQPQDCDSHCK 446
Score = 94.4 bits (233), Expect = 9e-19
Identities = 71/231 (30%), Positives = 89/231 (38%), Gaps = 40/231 (17%)
Query: 803 LCKPGVVGRRCDLCAPGYYGFGPTGCQA---CQCSHEGALSSLCEKTSGQCLCRTGAFGL 859
L +P G D+ A Y + T Q C+C+ + L + C CR G G
Sbjct: 224 LTRPSTAGDPRDMEAVVPYSYAATDLQVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGP 283
Query: 860 RCDRCQRGQWGFP----------SCRPCVCNGHADECNTHT-----------GACLGCRD 898
C RC+ P +C C CNGHA C + G CL CR
Sbjct: 284 DCGRCKPFYCDRPWQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRH 343
Query: 899 HTGGEHCERCIAGFHGDP--RLPYGGQCRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCH 955
+T G HC C GF+ DP L CR C C P G + +C+Q C
Sbjct: 344 NTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGK-----TCNQTTGQ----CP 394
Query: 956 CRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSG---NIDPMDPDACDPH 1003
C+ G TGL C CAPG F P C G + P+ P CD H
Sbjct: 395 CKDGVTGLTCNRCAPG-FQQSRSPVAPCVKTPIPGPTEDSSPVQPQDCDSH 444
Score = 85.5 bits (210), Expect = 4e-16
Identities = 56/176 (31%), Positives = 73/176 (41%), Gaps = 30/176 (17%)
Query: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF----WNLTSG--- 1089
RC CN + +C Q H C C +GP C RC P + W +
Sbjct: 254 RCKCN---GHASRCLLDTQGHLI-----CDCRHGTEGPDCGRCKPFYCDRPWQRATARES 305
Query: 1090 HGCQPCAC--HPSRARGP------TCNEFTGQC-HCRAGFGGRTCSECQELHWGDPGLQ- 1139
H C C+C H R R + G C +CR GR C C+E + DPG
Sbjct: 306 HACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRAL 365
Query: 1140 -----CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHPC 1190
C ACDC G C++ TG C C+ GV+G+ C++CA GF PC
Sbjct: 366 SDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGFQQSRSPVAPC 421
Score = 84.0 bits (206), Expect = 1e-15
Identities = 55/171 (32%), Positives = 70/171 (40%), Gaps = 37/171 (21%)
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLR---------CLHHTEGPHCAHCKPGFHGQ- 1029
GGRC+ C+ H +CL C H TEGP C CKP + +
Sbjct: 252 GGRCK---------------CNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRP 296
Query: 1030 ----AARQS--CHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC-PCLPNVQGPSCDRCAPN 1082
AR+S C C+CN + + S G C C N G C C
Sbjct: 297 WQRATARESHACLACSCNGHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREG 356
Query: 1083 FWN-----LTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128
F+ L+ C+ C CHP A G TCN+ TGQC C+ G G TC+ C
Sbjct: 357 FYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRC 407
Score = 65.5 bits (158), Expect = 5e-10
Identities = 34/88 (38%), Positives = 41/88 (46%), Gaps = 8/88 (9%)
Query: 799 GGQCL-CKPGVVGRRCDLCAPGYYG------FGPTGCQACQCSHEGALSSLCEKTSGQCL 851
GG CL C+ GR C C G+Y C+AC C GA C +T+GQC
Sbjct: 335 GGVCLNCRHNTAGRHCHYCREGFYRDPGRALSDRRACRACDCHPVGAAGKTCNQTTGQCP 394
Query: 852 CRTGAFGLRCDRCQRG-QWGFPSCRPCV 878
C+ G GL C+RC G Q PCV
Sbjct: 395 CKDGVTGLTCNRCAPGFQQSRSPVAPCV 422
Score = 62.0 bits (149), Expect = 5e-09
Identities = 46/168 (27%), Positives = 64/168 (38%), Gaps = 32/168 (19%)
Query: 418 QDGGRCDSHDDPALGLVSGQ----CRCKEHVVGTRCQQCRDGFFG-----LSISDRLGCR 468
Q GGRC + + L+ Q C C+ G C +C+ + + + C
Sbjct: 250 QVGGRCKCNGHASRCLLDTQGHLICDCRHGTEGPDCGRCKPFYCDRPWQRATARESHACL 309
Query: 469 RCQCNARGTVPGSTPCDPN-----------SGSCY-CKRLVTGRGCDRCLPGHW-----G 511
C CN + C N G C C+ GR C C G +
Sbjct: 310 ACSCNGH-----ARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYRDPGRA 364
Query: 512 LSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
LS D CR CDC GA C++ TGQC C+ + G C + PG+
Sbjct: 365 LS-DRRACRACDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 50.4 bits (119), Expect = 2e-05
Identities = 19/38 (50%), Positives = 23/38 (60%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGY 820
C C+P G+ CN GQC CK GV G C+ CAPG+
Sbjct: 374 CDCHPVGAAGKTCNQTTGQCPCKDGVTGLTCNRCAPGF 411
Score = 31.6 bits (70), Expect = 7.3
Identities = 28/114 (24%), Positives = 42/114 (36%), Gaps = 29/114 (25%)
Query: 469 RCQCNARGT-----VPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLL 517
RC+CN + G CD C+ G C RC P + W + +
Sbjct: 254 RCKCNGHASRCLLDTQGHLICD-------CRHGTEGPDCGRCKPFYCDRPWQRATARESH 306
Query: 518 GCRPCDCDVGGALDPQCD---------EGTGQC-HCRQHMVGRRCEQVQPGYFR 561
C C C+ G A + + G C +CR + GR C + G++R
Sbjct: 307 ACLACSCN-GHARRCRFNMELYRLSGRRSGGVCLNCRHNTAGRHCHYCREGFYR 359
>gi|122937440 multiple EGF-like-domains 9 [Homo sapiens]
Length = 639
Score = 192 bits (487), Expect = 3e-48
Identities = 98/250 (39%), Positives = 132/250 (52%), Gaps = 18/250 (7%)
Query: 783 CQCNPQGSLS-SECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTG-CQACQCSHEGALS 840
C C+ GSL+ + CN GQC C+PG G C+ C G+Y +G CQ C CS GALS
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHGALS 300
Query: 841 SLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS--CRPCVCNGHADECNTHTGACLGCRD 898
C +SG+C C+ G G CDRCQ G +GF C PC CN + C+ TGACL C++
Sbjct: 301 IPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNRSASCDALTGACLNCQE 359
Query: 899 HTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC-HCR 957
++ G HCE C GF+ P +C CPC S SC + C C+
Sbjct: 360 NSKGNHCEECKEGFYQSPDAT--KECLRCPC-----SAVTSTGSCSIKSSELEPECDQCK 412
Query: 958 AGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPM-DPDACDPHTGQCLRCLHHTEG 1016
GY G C C G++ S C+ C+C G++DP+ P C P +G+C+ CLH+T G
Sbjct: 413 DGYIGPNCNKCENGYYNFDS----ICRKCQCHGHVDPVKTPKICKPESGECINCLHNTTG 468
Query: 1017 PHCAHCKPGF 1026
C +C G+
Sbjct: 469 FWCENCLEGY 478
Score = 113 bits (282), Expect = 2e-24
Identities = 81/255 (31%), Positives = 114/255 (44%), Gaps = 34/255 (13%)
Query: 882 HADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPY-GGQCRPCPCPEGPGSQRHFA 940
+ + CN TG C CR G HCE C GF+ L Y G C+PC C H A
Sbjct: 250 NVNRCNQTTGQC-ECRPGYQGLHCETCKEGFY----LNYTSGLCQPCDCSP------HGA 298
Query: 941 TSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDAC 1000
S + + C C+ G G C+ C G++G S+ G C C+C+ +C
Sbjct: 299 LSIPCNSSGK---CQCKVGVIGSICDRCQDGYYGF-SKNG--CLPCQCNNR-----SASC 347
Query: 1001 DPHTGQCLRCLHHTEGPHCAHCKPGFH-GQAARQSCHRCTCNLLGTNPQQCPSPDQCHCD 1059
D TG CL C +++G HC CK GF+ A + C RC C+ + T+ C S +
Sbjct: 348 DALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAV-TSTGSC-SIKSSELE 405
Query: 1060 PSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCAC--HPSRARGP-TCNEFTGQC-H 1115
P QC GP+C++C ++N S C+ C C H + P C +G+C +
Sbjct: 406 PECDQCK--DGYIGPNCNKCENGYYNFDS--ICRKCQCHGHVDPVKTPKICKPESGECIN 461
Query: 1116 CRAGFGGRTCSECQE 1130
C G C C E
Sbjct: 462 CLHNTTGFWCENCLE 476
Score = 110 bits (275), Expect = 1e-23
Identities = 66/213 (30%), Positives = 92/213 (43%), Gaps = 40/213 (18%)
Query: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSS 841
PC C+P G+LS CN G+C CK GV+G CD C GYYGF GC CQC++ S+
Sbjct: 290 PCDCSPHGALSIPCN-SSGKCQCKVGVIGSICDRCQDGYYGFSKNGCLPCQCNNR---SA 345
Query: 842 LCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP----SCRPCVCNG--HADECNTHTG--- 891
C+ +G CL C+ + G C+ C+ G + P C C C+ C+ +
Sbjct: 346 SCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELE 405
Query: 892 -ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQ 950
C C+D G +C +C G++ + CR C C H D
Sbjct: 406 PECDQCKDGYIGPNCNKCENGYYN-----FDSICRKCQC------------HGHVDPVKT 448
Query: 951 QIVC--------HCRAGYTGLRCEACAPGHFGD 975
+C +C TG CE C G+ D
Sbjct: 449 PKICKPESGECINCLHNTTGFWCENCLEGYVHD 481
Score = 104 bits (260), Expect = 7e-22
Identities = 68/223 (30%), Positives = 95/223 (42%), Gaps = 23/223 (10%)
Query: 985 LCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLG 1044
+C CS + ++ + C+ TGQC C +G HC CK GF+ C C C+ G
Sbjct: 240 VCNCSV-VGSLNVNRCNQTTGQC-ECRPGYQGLHCETCKEGFYLNYTSGLCQPCDCSPHG 297
Query: 1045 TNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARG 1104
C S SG+C C V G CDRC ++ S +GC PC C+ R
Sbjct: 298 ALSIPCNS---------SGKCQCKVGVIGSICDRCQDGYYGF-SKNGCLPCQCNN---RS 344
Query: 1105 PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDPGL--QCHACDCD---SRGIDTPQCHRF 1158
+C+ TG C +C+ G C EC+E + P +C C C S G + +
Sbjct: 345 ASCDALTGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSEL 404
Query: 1159 TGHCS-CRPGVSGVRCDQCARGFSGIFPACHPCHACFGDWDRV 1200
C C+ G G C++C G+ C C C G D V
Sbjct: 405 EPECDQCKDGYIGPNCNKCENGYYNFDSICRKCQ-CHGHVDPV 446
Score = 103 bits (257), Expect = 2e-21
Identities = 63/204 (30%), Positives = 93/204 (45%), Gaps = 41/204 (20%)
Query: 368 NVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHD 427
N + G C+ C+ G HCE C+ FY + T L C+ CDC P G+ C+S
Sbjct: 255 NQTTGQCE-CRPGYQGLHCETCKEGFYLNYTSGL-----CQPCDCSPHGALSIP-CNS-- 305
Query: 428 DPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPN 487
SG+C+CK V+G+ C +C+DG++G S + GC CQCN R S CD
Sbjct: 306 -------SGKCQCKVGVIGSICDRCQDGYYGFS---KNGCLPCQCNNR-----SASCDAL 350
Query: 488 SGSCY-CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDV----------GGALDPQCDE 536
+G+C C+ G C+ C G + C C C L+P+CD+
Sbjct: 351 TGACLNCQENSKGNHCEECKEGFYQSPDATKECLRCPCSAVTSTGSCSIKSSELEPECDQ 410
Query: 537 GTGQCHCRQHMVGRRCEQVQPGYF 560
C+ +G C + + GY+
Sbjct: 411 ------CKDGYIGPNCNKCENGYY 428
Score = 100 bits (250), Expect = 1e-20
Identities = 73/254 (28%), Positives = 102/254 (40%), Gaps = 54/254 (21%)
Query: 271 YYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRD 330
+Y Y + C C H + P + G C CK G C++CQD Y
Sbjct: 279 FYLNYTSGLCQPCDCSPHGALSIPCNSS---------GKCQCKVGVIGSICDRCQDGYYG 329
Query: 331 LPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCR 390
+ C C+C+ + SC + G C CQ N+ G HCE C+
Sbjct: 330 FS--------KNGCLPCQCNNRSASC-----------DALTGACLNCQENSKGNHCEECK 370
Query: 391 PFFYRDP--TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGT 447
FY+ P TK+ C C C + S G C + +C +CK+ +G
Sbjct: 371 EGFYQSPDATKE------CLRCPCSAVTST--GSCSIKSSE----LEPECDQCKDGYIGP 418
Query: 448 RCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP--CDPNSGSCY-CKRLVTGRGCDR 504
C +C +G++ CR+CQC+ P TP C P SG C C TG C+
Sbjct: 419 NCNKCENGYYNFDSI----CRKCQCHGH-VDPVKTPKICKPESGECINCLHNTTGFWCEN 473
Query: 505 CLPGHWGLSHDLLG 518
CL G+ HDL G
Sbjct: 474 CLEGY---VHDLEG 484
Score = 39.3 bits (90), Expect = 0.035
Identities = 16/40 (40%), Positives = 25/40 (62%), Gaps = 1/40 (2%)
Query: 522 CDCDVGGALDP-QCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
C+C V G+L+ +C++ TGQC CR G CE + G++
Sbjct: 241 CNCSVVGSLNVNRCNQTTGQCECRPGYQGLHCETCKEGFY 280
>gi|181336739 multiple EGF-like-domains 11 [Homo sapiens]
Length = 1044
Score = 177 bits (448), Expect = 1e-43
Identities = 131/414 (31%), Positives = 171/414 (41%), Gaps = 82/414 (19%)
Query: 781 LPCQCNPQGSLSSE---------CNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQA 830
LPC G +E C+P G C C PG +G C+L C G +G + +
Sbjct: 478 LPCPSGTWGLNCNESCTCANGAACSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCS--EH 535
Query: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCR-PCVCNGHADECNT 888
C CSH C+ +G C C G G+RCD C G+WG P+C C C + C+
Sbjct: 536 CDCSHADG----CDPVTGHCCCLAGWTGIRCDSTCPPGRWG-PNCSVSCSCE-NGGSCSP 589
Query: 889 HTGACLGCRDHTGGEHCER-CIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDE 947
G+C C G C+R C GF+G G +PCP H + CH
Sbjct: 590 EDGSC-ECAPGFRGPLCQRICPPGFYGH------GCAQPCPLCV------HSSRPCHHIS 636
Query: 948 YSQQIVCHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQ 1006
+C C G++G C + CA G+FG QLC C+ N C P G
Sbjct: 637 G----ICECLPGFSGALCNQVCAGGYFGQDC-----AQLCSCANN------GTCSPIDGS 681
Query: 1007 CLRCLHHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQC 1065
C +C G C+ C PGF G A H C+C+ + C G C
Sbjct: 682 C-QCFPGWIGKDCSQACPPGFWGPAC---FHACSCH------------NGASCSAEDGAC 725
Query: 1066 PCLPNVQGPSC-DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRT 1124
C P G C RC F+ G CQ C G +C+ +G+C CR GF G+
Sbjct: 726 HCTPGWTGLFCTQRCPAAFFGKDCGRVCQ---CQ----NGASCDHISGKCTCRTGFTGQH 778
Query: 1125 CSECQELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA 1177
C Q G G C C+C ++ C TG C C PG G+RCDQ A
Sbjct: 779 CE--QRCAPGTFGYGCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQAA 826
Score = 172 bits (437), Expect = 2e-42
Identities = 142/468 (30%), Positives = 171/468 (36%), Gaps = 128/468 (27%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYG----------------- 822
LPCQC S C+P G+CLC PG G C +LC PG +G
Sbjct: 187 LPCQCRHGAS----CDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQNGGTCHH 242
Query: 823 ------------------------FGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFG 858
FG Q C C H G C+ +GQC C G G
Sbjct: 243 ITGECACPPGWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQ----CDHVTGQCHCTAGYMG 298
Query: 859 LRC-DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCER--CIAGFHGD 915
RC + C G +GF + C C+ + +C+ TGAC C G C+ C G HG
Sbjct: 299 DRCQEECPFGSFGFQCSQHCDCH-NGGQCSPTTGAC-ECEPGYKGPRCQERLCPEGLHGP 356
Query: 916 PRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRC-EACAPGHFG 974
G PCPC H T C C+ G++G C E+C G++G
Sbjct: 357 ------GCTLPCPCDADNTISCHPVTG----------ACTCQPGWSGHHCNESCPVGYYG 400
Query: 975 DPSRPGGRCQL-CECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQ 1033
D CQL C C D C TG C C PGF G+
Sbjct: 401 D------GCQLPCTCQNGAD------CHSITGGCT-------------CAPGFMGEVCAV 435
Query: 1034 SCHRCTCNLLGTNPQQCPSPDQCH----CDPSSGQCPCLPNVQGPSCD-RCAPNFWNLTS 1088
SC GT C S C+ C P G C C QG C C W L
Sbjct: 436 SC------AAGTYGPNCSSICSCNNGGTCSPVDGSCTCKEGWQGLDCTLPCPSGTWGLNC 489
Query: 1089 GHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQC-HACDCD 1146
+ C C A G C+ G C C G+ G TC C + G GL C CDC
Sbjct: 490 N---ESCTC----ANGAACSPIDGSCSCTPGWLGDTCELPCPD---GTFGLNCSEHCDCS 539
Query: 1147 SRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSGIFPACHPCHAC 1193
C TGHC C G +G+RCD C G G P C +C
Sbjct: 540 ----HADGCDPVTGHCCCLAGWTGIRCDSTCPPGRWG--PNCSVSCSC 581
Score = 168 bits (426), Expect = 4e-41
Identities = 134/412 (32%), Positives = 168/412 (40%), Gaps = 81/412 (19%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQ-ACQCSHEGALS 840
CQC G+L CNP G C+C G G RC +LCAPG +G GCQ CQC H
Sbjct: 146 CQCQ-NGAL---CNPITGACVCAAGFRGWRCEELCAPGTHG---KGCQLPCQCRH----G 194
Query: 841 SLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
+ C+ +G+CLC G G+ C+ C G G C C + C+ TG C
Sbjct: 195 ASCDPRAGECLCAPGYTGVYCEELCPPGSHGAHCELRCPCQ-NGGTCHHITGECACPPGW 253
Query: 900 TGGEHCERCIAGFHGDPRLPYGGQC-RPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
TG + C G +G C + CPC H C D + Q CHC A
Sbjct: 254 TGAVCAQPCPPG-------TFGQNCSQDCPC--------HHGGQC--DHVTGQ--CHCTA 294
Query: 959 GYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
GY G RC E C G FG +CS + D + C P TG C C +GP
Sbjct: 295 GYMGDRCQEECPFGSFG-----------FQCSQHCDCHNGGQCSPTTGAC-ECEPGYKGP 342
Query: 1018 HCAH--CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPS 1075
C C G HG T P C + + C P +G C C P G
Sbjct: 343 RCQERLCPEGLHGPGC-------------TLPCPCDADNTISCHPVTGACTCQPGWSGHH 389
Query: 1076 CDRCAPNFWNLTSGHGCQ-PCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHW 1133
C+ P + G GCQ PC C G C+ TG C C GF G C+ C
Sbjct: 390 CNESCPVGY---YGDGCQLPCTCQ----NGADCHSITGGCTCAPGFMGEVCAVSCAA--- 439
Query: 1134 GDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCD-QCARGFSGI 1183
G G C + C C++ G C G C+C+ G G+ C C G G+
Sbjct: 440 GTYGPNCSSICSCNNGG----TCSPVDGSCTCKEGWQGLDCTLPCPSGTWGL 487
Score = 94.4 bits (233), Expect = 9e-19
Identities = 80/286 (27%), Positives = 97/286 (33%), Gaps = 107/286 (37%)
Query: 998 DACDPH-TGQCL--RCLHHTEGPHCAHCKPGFHGQAARQSC----------HRCTCN--- 1041
D C P T +C+ RC+ P HC+PG+ G C +RC C
Sbjct: 97 DFCIPLCTEECVHGRCV----SPDTCHCEPGWGGPDCSSGCDSDHWGPHCSNRCQCQNGA 152
Query: 1042 ------------------------LLGTNPQQCPSPDQCH----CDPSSGQCPCLPNVQG 1073
GT+ + C P QC CDP +G+C C P G
Sbjct: 153 LCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQLPCQCRHGASCDPRAGECLCAPGYTG 212
Query: 1074 PSCDR-------------------------------CAPNFWNLTSGHGCQP-------- 1094
C+ C P + C P
Sbjct: 213 VYCEELCPPGSHGAHCELRCPCQNGGTCHHITGECACPPGWTGAVCAQPCPPGTFGQNCS 272
Query: 1095 --CACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQC-HACDCDSRGID 1151
C CH G C+ TGQCHC AG+ G C E E +G G QC CDC + G
Sbjct: 273 QDCPCH----HGGQCDHVTGQCHCTAGYMGDRCQE--ECPFGSFGFQCSQHCDCHNGG-- 324
Query: 1152 TPQCHRFTGHCSCRPGVSGVRCDQ--CARGFSGIFPACH---PCHA 1192
QC TG C C PG G RC + C G G P C PC A
Sbjct: 325 --QCSPTTGACECEPGYKGPRCQERLCPEGLHG--PGCTLPCPCDA 366
Score = 77.0 bits (188), Expect = 2e-13
Identities = 69/253 (27%), Positives = 92/253 (36%), Gaps = 67/253 (26%)
Query: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR-KCECHGHTHSCHFDMAVYL 364
+ GAC+C RG CE+ A H C+ C+C H SC L
Sbjct: 157 ITGACVCAAGFRGWRCEELC----------APGTHGKGCQLPCQCR-HGASCDPRAGECL 205
Query: 365 ASGNVSGGVCDG-CQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRC 423
+ +G C+ C + G HCEL C C Q+GG C
Sbjct: 206 CAPGYTGVYCEELCPPGSHGAHCEL--------------------RCPC-----QNGGTC 240
Query: 424 DSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGST 482
++G+C C G C Q C G FG + S + C C+ G
Sbjct: 241 HH--------ITGECACPPGWTGAVCAQPCPPGTFGQNCS-----QDCPCHHGGQ----- 282
Query: 483 PCDPNSGSCYCKRLVTGRGC-DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC 541
CD +G C+C G C + C G +G + CDC GG QC TG C
Sbjct: 283 -CDHVTGQCHCTAGYMGDRCQEECPFGSFGFQCS----QHCDCHNGG----QCSPTTGAC 333
Query: 542 HCRQHMVGRRCEQ 554
C G RC++
Sbjct: 334 ECEPGYKGPRCQE 346
Score = 75.5 bits (184), Expect = 4e-13
Identities = 67/261 (25%), Positives = 96/261 (36%), Gaps = 45/261 (17%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASG 367
G C+C G+ CE+ P G +H +C C + +CH
Sbjct: 202 GECLCAPGYTGVYCEELCP--------PGSHG-AHCELRCPCQ-NGGTCHHITGECACPP 251
Query: 368 NVSGGVC-DGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRS----------CDCDPMG 416
+G VC C T G++C P + + C + C G
Sbjct: 252 GWTGAVCAQPCPPGTFGQNCSQDCPCHHGGQCDHVTGQCHCTAGYMGDRCQEECPFGSFG 311
Query: 417 SQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ--CRDGFFGLSISDRLGCR-RCQCN 473
Q CD H+ +G C C+ G RCQ+ C +G G GC C C+
Sbjct: 312 FQCSQHCDCHNGGQCSPTTGACECEPGYKGPRCQERLCPEGLHG------PGCTLPCPCD 365
Query: 474 ARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLP-GHWGLSHDLLGCR-PCDCDVGGALD 531
A T+ C P +G+C C+ +G C+ P G++G GC+ PC C G
Sbjct: 366 ADNTI----SCHPVTGACTCQPGWSGHHCNESCPVGYYG-----DGCQLPCTCQNGA--- 413
Query: 532 PQCDEGTGQCHCRQHMVGRRC 552
C TG C C +G C
Sbjct: 414 -DCHSITGGCTCAPGFMGEVC 433
Score = 73.9 bits (180), Expect = 1e-12
Identities = 76/289 (26%), Positives = 100/289 (34%), Gaps = 64/289 (22%)
Query: 281 GNCFCYGHASECAPAPGAPA---------HAEGMVHGACICKHNTRGLNCEQCQDFYRDL 331
G+C + ECAP P + G +C H++R C L
Sbjct: 585 GSCSPEDGSCECAPGFRGPLCQRICPPGFYGHGCAQPCPLCVHSSRP--CHHISGICECL 642
Query: 332 PWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQ--HNTAGRHC-EL 388
P G S A C G A+ + CQ G+ C +
Sbjct: 643 P------GFSGALCNQVCAGGYFGQDCAQLCSCANNGTCSPIDGSCQCFPGWIGKDCSQA 696
Query: 389 CRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTR 448
C P F+ PA +C C +G C + D G C C G
Sbjct: 697 CPPGFW--------GPACFHACSC-----HNGASCSAED--------GACHCTPGWTGLF 735
Query: 449 C-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-RCL 506
C Q+C FFG R CQC CD SG C C+ TG+ C+ RC
Sbjct: 736 CTQRCPAAFFGKDCG-----RVCQCQ------NGASCDHISGKCTCRTGFTGQHCEQRCA 784
Query: 507 PGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ 554
PG +G GC+ C+C + CD TG C+C G RC+Q
Sbjct: 785 PGTFGY-----GCQQLCEC----MNNSTCDHVTGTCYCSPGFKGIRCDQ 824
Score = 72.4 bits (176), Expect = 4e-12
Identities = 75/291 (25%), Positives = 97/291 (33%), Gaps = 73/291 (25%)
Query: 280 RGNCFCYGHASECAPAPGA------PAHAEGMVHGACICK---HNTRGLNCEQCQDFYRD 330
RG Y S+C P P E VHG C+ H G C
Sbjct: 76 RGLRTMYRRRSQCCPGYYESGDFCIPLCTEECVHGRCVSPDTCHCEPGWGGPDCSSGCDS 135
Query: 331 LPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG-CQHNTAGRHCELC 389
W P H +C+C C+ + + G C+ C T G+ C+L
Sbjct: 136 DHWGP------HCSNRCQCQNGA-LCNPITGACVCAAGFRGWRCEELCAPGTHGKGCQL- 187
Query: 390 RPFFYRDPTKDLRDPAVCR-SCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTR 448
P CR CDP +G+C C G
Sbjct: 188 --------------PCQCRHGASCDPR-------------------AGECLCAPGYTGVY 214
Query: 449 CQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CL 506
C++ C G G RC C GT C +G C C TG C + C
Sbjct: 215 CEELCPPGSHGAHCE-----LRCPCQNGGT------CHHITGECACPPGWTGAVCAQPCP 263
Query: 507 PGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
PG +G + + C C GG QCD TGQCHC +G RC++ P
Sbjct: 264 PGTFGQNCS----QDCPCHHGG----QCDHVTGQCHCTAGYMGDRCQEECP 306
Score = 69.7 bits (169), Expect = 2e-11
Identities = 79/304 (25%), Positives = 103/304 (33%), Gaps = 81/304 (26%)
Query: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG-H 340
+C C+ + +C+P GA C C+ +G C++ R +G H
Sbjct: 317 HCDCH-NGGQCSPTTGA-----------CECEPGYKGPRCQE----------RLCPEGLH 354
Query: 341 SHACR-KCECHG-HTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHC-ELCRPFFYRDP 397
C C C +T SCH G C CQ +G HC E C +Y D
Sbjct: 355 GPGCTLPCPCDADNTISCH-----------PVTGACT-CQPGWSGHHCNESCPVGYYGDG 402
Query: 398 TK---DLRDPAVCRS----CDCDP---------------MGSQDGGRCDSHDDPALGLVS 435
+ ++ A C S C C P G C ++ V
Sbjct: 403 CQLPCTCQNGADCHSITGGCTCAPGFMGEVCAVSCAAGTYGPNCSSICSCNNGGTCSPVD 462
Query: 436 GQCRCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCK 494
G C CKE G C C G +GL+ CN T C P GSC C
Sbjct: 463 GSCTCKEGWQGLDCTLPCPSGTWGLN-----------CNESCTCANGAACSPIDGSCSCT 511
Query: 495 RLVTGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
G C+ C G +GL+ CDC CD TG C C G RC+
Sbjct: 512 PGWLGDTCELPCPDGTFGLNCS----EHCDCSHADG----CDPVTGHCCCLAGWTGIRCD 563
Query: 554 QVQP 557
P
Sbjct: 564 STCP 567
Score = 63.9 bits (154), Expect = 1e-09
Identities = 82/326 (25%), Positives = 107/326 (32%), Gaps = 76/326 (23%)
Query: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACI--CKHNTRGLNC-EQCQDFYRDLPWRPAED 338
+C C A+ C+P G+ + G + C C T GLNC E C + D +
Sbjct: 492 SCTCANGAA-CSPIDGSCSCTPGWLGDTCELPCPDGTFGLNCSEHCDCSHAD----GCDP 546
Query: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
H C G + + +VS +G + CE C P F
Sbjct: 547 VTGHCCCLAGWTGIRCDSTCPPGRWGPNCSVSCSCENGGSCSPEDGSCE-CAPGF----- 600
Query: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDS--HDDPALGLVSGQCRCKEHVVGTRCQQ-CRDG 455
R P R C G C H +SG C C G C Q C G
Sbjct: 601 ---RGPLCQRICPPGFYGHGCAQPCPLCVHSSRPCHHISGICECLPGFSGALCNQVCAGG 657
Query: 456 FFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGLS- 513
+FG + + C C GT C P GSC C G+ C + C PG WG +
Sbjct: 658 YFGQDCA-----QLCSCANNGT------CSPIDGSCQCFPGWIGKDCSQACPPGFWGPAC 706
Query: 514 ------HDLLGC--------------------------------RPCDCDVGGALDPQCD 535
H+ C R C C G + CD
Sbjct: 707 FHACSCHNGASCSAEDGACHCTPGWTGLFCTQRCPAAFFGKDCGRVCQCQNGAS----CD 762
Query: 536 EGTGQCHCRQHMVGRRCEQ-VQPGYF 560
+G+C CR G+ CEQ PG F
Sbjct: 763 HISGKCTCRTGFTGQHCEQRCAPGTF 788
>gi|14192943 multiple EGF-like-domains 10 [Homo sapiens]
Length = 1140
Score = 175 bits (444), Expect = 3e-43
Identities = 141/450 (31%), Positives = 178/450 (39%), Gaps = 99/450 (22%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQACQCSHEGALSS 841
CQC + C+ G+C C PG G C DLC PG +G P Q C C + G
Sbjct: 195 CQCQN----GATCDHVTGECRCPPGYTGAFCEDLCPPGKHG--PQCEQRCPCQNGG---- 244
Query: 842 LCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHT 900
+C +G+C C +G G C + C G++G + C C+ + C+ TG C +T
Sbjct: 245 VCHHVTGECSCPSGWMGTVCGQPCPEGRFGKNCSQECQCH-NGGTCDAATGQCHCSPGYT 303
Query: 901 GGEHCERCIAGFHG-----DPRLPYGGQCR----PCPCPEGPGSQRHFATSCHQDEYS-- 949
G + C G +G + GG+C C C G +R A C + Y
Sbjct: 304 GERCQDECPVGTYGVLCAETCQCVNGGKCYHVSGACLCEAGFAGERCEARLCPEGLYGIK 363
Query: 950 --QQIVCH---------------CRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGN 991
++ CH C+ G++GL C E C+PG +G+ + Q+C C
Sbjct: 364 CDKRCPCHLENTHSCHPMSGECACKPGWSGLYCNETCSPGFYGEACQ-----QICSCQNG 418
Query: 992 IDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQQCP 1051
D CD TG+C C PGF G C LGT C
Sbjct: 419 AD------CDSVTGKCT-------------CAPGFKGIDCSTPCP------LGTYGINCS 453
Query: 1052 SPDQCH----CDPSSGQCPCLPNVQGPSCD-RCAPNFWNLTSGHGCQ-PCACHPSRARGP 1105
S C C P G C C G C RC W G GC C C G
Sbjct: 454 SRCGCKNDAVCSPVDGSCTCKAGWHGVDCSIRCPSGTW----GFGCNLTCQC----LNGG 505
Query: 1106 TCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCS 1163
CN G C C G+ G C CQ+ G GL C CDC CH TGHC
Sbjct: 506 ACNTLDGTCTCAPGWRGEKCELPCQD---GTYGLNCAERCDCSH----ADGCHPTTGHCR 558
Query: 1164 CRPGVSGVRCDQ-CARGFSGIFPACH-PCH 1191
C PG SGV CD CA G G P C PC+
Sbjct: 559 CLPGWSGVHCDSVCAEGRWG--PNCSLPCY 586
Score = 165 bits (418), Expect = 3e-40
Identities = 129/405 (31%), Positives = 158/405 (39%), Gaps = 81/405 (20%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGAL 839
L CQC G+ CN G C C PG G +C+L C G YG + C CSH
Sbjct: 497 LTCQCLNGGA----CNTLDGTCTCAPGWRGEKCELPCQDGTYGLNCA--ERCDCSHADG- 549
Query: 840 SSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCR-PCVCNGHADECNTHTGACLGCR 897
C T+G C C G G+ CD C G+WG P+C PC C A C+ G C C
Sbjct: 550 ---CHPTTGHCRCLPGWSGVHCDSVCAEGRWG-PNCSLPCYCKNGAS-CSPDDGIC-ECA 603
Query: 898 DHTGGEHCER-CIAGFHGDPRLPYGGQC-RPCP-CPEGPGSQRHFATSCHQDEYSQQIVC 954
G C+R C GF YG +C + CP C G H +C
Sbjct: 604 PGFRGTTCQRICSPGF-------YGHRCSQTCPQCVHSSGPCHHITG-----------LC 645
Query: 955 HCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHH 1013
C G+TG C E C G FG +C C+ N C+P C +C
Sbjct: 646 DCLPGFTGALCNEVCPSGRFGKNC-----AGICTCTNN------GTCNPIDRSC-QCYPG 693
Query: 1014 TEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQ 1072
G C+ C P G H C C+ + C G+C C P
Sbjct: 694 WIGSDCSQPCPPAHWGP---NCIHTCNCH------------NGAFCSAYDGECKCTPGWT 738
Query: 1073 GPSC-DRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQEL 1131
G C RC F+ + CA G C+ +GQC CR GF GR C Q+
Sbjct: 739 GLYCTQRCPLGFYG-------KDCALICQCQNGADCDHISGQCTCRTGFMGRHCE--QKC 789
Query: 1132 HWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
G G C CDC ++ C TG C C PG G RCDQ
Sbjct: 790 PSGTYGYGCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 87.8 bits (216), Expect = 9e-17
Identities = 76/254 (29%), Positives = 99/254 (38%), Gaps = 68/254 (26%)
Query: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG-HSHAC-RKCECH-GHTHSCHFDMAV 362
V GAC+C+ G CE R +G + C ++C CH +THSCH
Sbjct: 335 VSGACLCEAGFAGERCEA----------RLCPEGLYGIKCDKRCPCHLENTHSCH----- 379
Query: 363 YLASGNVSGGVCDGCQHNTAGRHC-ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG 421
G C C+ +G +C E C P FY + + + C C Q+G
Sbjct: 380 ------PMSGEC-ACKPGWSGLYCNETCSPGFYGEACQQI--------CSC-----QNGA 419
Query: 422 RCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPG 480
CDS V+G+C C G C C G +G++ S R GC+
Sbjct: 420 DCDS--------VTGKCTCAPGFKGIDCSTPCPLGTYGINCSSRCGCKN----------- 460
Query: 481 STPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTG 539
C P GSC CK G C RC G WG +L C C GGA C+ G
Sbjct: 461 DAVCSPVDGSCTCKAGWHGVDCSIRCPSGTWGFGCNL----TCQCLNGGA----CNTLDG 512
Query: 540 QCHCRQHMVGRRCE 553
C C G +CE
Sbjct: 513 TCTCAPGWRGEKCE 526
Score = 86.3 bits (212), Expect = 2e-16
Identities = 82/292 (28%), Positives = 108/292 (36%), Gaps = 52/292 (17%)
Query: 286 YGHASECAPA------PGAPAHAEGMVHGACI------CKHNTRGLNCEQCQDFYRDLPW 333
Y S+C P P A+ VHG CI C+ G NC D W
Sbjct: 88 YRRKSQCCPGFYESGEMCVPHCADKCVHGRCIAPNTCQCEPGWGGTNCSSACDGDH---W 144
Query: 334 RPAEDGHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCEL---CR 390
P H +C+C A + A+G D C+ T G C C+
Sbjct: 145 GP------HCTSRCQCKNGALCNPITGACHCAAGFRGWRCEDRCEQGTYGNDCHQRCQCQ 198
Query: 391 PFFYRDP-TKDLRDPAVCRSCDCDPM------GSQDGGRCDSHDDPALGLVSGQCRCKEH 443
D T + R P C+ + G Q RC + V+G+C C
Sbjct: 199 NGATCDHVTGECRCPPGYTGAFCEDLCPPGKHGPQCEQRCPCQNGGVCHHVTGECSCPSG 258
Query: 444 VVGTRC-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGC 502
+GT C Q C +G FG + S + CQC+ GT CD +G C+C TG C
Sbjct: 259 WMGTVCGQPCPEGRFGKNCS-----QECQCHNGGT------CDAATGQCHCSPGYTGERC 307
Query: 503 -DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
D C G +G+ L C C GG +C +G C C G RCE
Sbjct: 308 QDECPVGTYGV----LCAETCQCVNGG----KCYHVSGACLCEAGFAGERCE 351
Score = 73.6 bits (179), Expect = 2e-12
Identities = 74/292 (25%), Positives = 104/292 (35%), Gaps = 66/292 (22%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C+C AS C+P G C C RG C++ P GH
Sbjct: 585 CYCKNGAS-CSPDDGI-----------CECAPGFRGTTCQRICS--------PGFYGHRC 624
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDG-CQHNTAGRHCE-LCRPFFYRDPTKD 400
+ +C + CH + +G +C+ C G++C +C T +
Sbjct: 625 SQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGICTC------TNN 678
Query: 401 LRDPAVCRSCDCDP---------------MGSQDGGRCDSHDDPALGLVSGQCRCKEHVV 445
+ RSC C P G C+ H+ G+C+C
Sbjct: 679 GTCNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAYDGECKCTPGWT 738
Query: 446 GTRC-QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD- 503
G C Q+C GF+G + CQC CD SG C C+ GR C+
Sbjct: 739 GLYCTQRCPLGFYGKDCA-----LICQCQ------NGADCDHISGQCTCRTGFMGRHCEQ 787
Query: 504 RCLPGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ 554
+C G +G GCR CDC + CD TG C+C G RC+Q
Sbjct: 788 KCPSGTYGY-----GCRQICDC----LNNSTCDHITGTCYCSPGWKGARCDQ 830
Score = 70.9 bits (172), Expect = 1e-11
Identities = 80/303 (26%), Positives = 100/303 (33%), Gaps = 77/303 (25%)
Query: 308 GACICKHNTRGLNCE-QCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYLAS 366
G C C RG CE CQD L + +C+C H CH
Sbjct: 512 GTCTCAPGWRGEKCELPCQDGTYGL----------NCAERCDC-SHADGCHPTTGHCRCL 560
Query: 367 GNVSGGVCDG-CQHNTAGRHCELCRPFFYRDPTKDLRDPAVC------RSCDCDPMGSQD 419
SG CD C G +C L P + ++ D +C R C + S
Sbjct: 561 PGWSGVHCDSVCAEGRWGPNCSL--PCYCKNGASCSPDDGICECAPGFRGTTCQRICSPG 618
Query: 420 --GGRCDS------HDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRC 470
G RC H ++G C C G C + C G FG + + C
Sbjct: 619 FYGHRCSQTCPQCVHSSGPCHHITGLCDCLPGFTGALCNEVCPSGRFGKNCAGI-----C 673
Query: 471 QCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGLS-------HDLLGCRP- 521
C GT C+P SC C G C + C P HWG + H+ C
Sbjct: 674 TCTNNGT------CNPIDRSCQCYPGWIGSDCSQPCPPAHWGPNCIHTCNCHNGAFCSAY 727
Query: 522 ---CDCDVGG------------------ALDPQCDEG------TGQCHCRQHMVGRRCEQ 554
C C G AL QC G +GQC CR +GR CEQ
Sbjct: 728 DGECKCTPGWTGLYCTQRCPLGFYGKDCALICQCQNGADCDHISGQCTCRTGFMGRHCEQ 787
Query: 555 VQP 557
P
Sbjct: 788 KCP 790
Score = 68.2 bits (165), Expect = 7e-11
Identities = 72/285 (25%), Positives = 96/285 (33%), Gaps = 85/285 (29%)
Query: 288 HASECAPAPGAPAHAEGMVH---GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGH--SH 342
H +C P G+ H G C C G C Q P +G +
Sbjct: 230 HGPQCEQR--CPCQNGGVCHHVTGECSCPSGWMGTVCGQ-----------PCPEGRFGKN 276
Query: 343 ACRKCECHGH------THSCHFDMAVYLASGNVSGGVC-DGCQHNTAGRHCELCRPFFYR 395
++C+CH T CH S +G C D C T G C
Sbjct: 277 CSQECQCHNGGTCDAATGQCH-------CSPGYTGERCQDECPVGTYGVLC--------- 320
Query: 396 DPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ--CR 453
+C C +GG+C VSG C C+ G RC+ C
Sbjct: 321 -----------AETCQC-----VNGGKCYH--------VSGACLCEAGFAGERCEARLCP 356
Query: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGL 512
+G +G+ +RC C+ T C P SG C CK +G C+ C PG +G
Sbjct: 357 EGLYGIKCD-----KRCPCHLENT----HSCHPMSGECACKPGWSGLYCNETCSPGFYGE 407
Query: 513 SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
+ + C C G CD TG+C C G C P
Sbjct: 408 ACQQI----CSCQNGA----DCDSVTGKCTCAPGFKGIDCSTPCP 444
>gi|24308065 netrin 5 [Homo sapiens]
Length = 489
Score = 175 bits (444), Expect = 3e-43
Identities = 86/217 (39%), Positives = 115/217 (52%), Gaps = 22/217 (10%)
Query: 279 VRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
+RG C C+GHA+ CA P C C+H+T G CE C+ +RD PWRPA
Sbjct: 153 LRGRCQCHGHAARCAARARPPR---------CHCRHHTTGPGCESCRPSHRDWPWRPATP 203
Query: 339 GHSHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPT 398
H H C C C+ H C F+ ++ SG SGGVC+ C+H+TAGRHC C+P F+RDP+
Sbjct: 204 RHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPS 263
Query: 399 KDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFG 458
+ + CR+C C P+G+ GG C+ SGQC CK V G C +C G +
Sbjct: 264 QPIFSRRACRACQCHPIGA-TGGTCNQ--------TSGQCTCKLGVTGLTCNRCGPG-YQ 313
Query: 459 LSISDRLGCRRC--QCNARGTVPGSTPCDPNSGSCYC 493
S S R+ C+R T PG+ DP + YC
Sbjct: 314 QSRSPRMPCQRIPEATTTLATTPGAYSSDPQCQN-YC 349
Score = 85.9 bits (211), Expect = 3e-16
Identities = 49/153 (32%), Positives = 65/153 (42%), Gaps = 38/153 (24%)
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHT--------- 1004
CHCR TG CE+C P H P RP + P P +C+ H
Sbjct: 175 CHCRHHTTGPGCESCRPSHRDWPWRPA-------TPRHPHPCLPCSCNQHARRCRFNSEL 227
Query: 1005 ---------GQCLRCLHHTEGPHCAHCKPGFHGQA-----ARQSCHRCTCNLLGTNPQQC 1050
G C RC HHT G HC +C+PGF +R++C C C+ +G
Sbjct: 228 FRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGT- 286
Query: 1051 PSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF 1083
C+ +SGQC C V G +C+RC P +
Sbjct: 287 -------CNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 85.1 bits (209), Expect = 6e-16
Identities = 49/156 (31%), Positives = 63/156 (40%), Gaps = 17/156 (10%)
Query: 986 CECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQS-------CHRC 1038
C+C G+ A P C HHT GP C C+P R + C C
Sbjct: 157 CQCHGHAARCAARARPPRC----HCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
Query: 1039 TCNLLGTNPQQCPSPDQCHCDPSSGQCP-CLPNVQGPSCDRCAPNFWN-----LTSGHGC 1092
+CN + + S G C C + G C C P FW + S C
Sbjct: 213 SCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRAC 272
Query: 1093 QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSEC 1128
+ C CHP A G TCN+ +GQC C+ G G TC+ C
Sbjct: 273 RACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRC 308
Score = 83.2 bits (204), Expect = 2e-15
Identities = 58/179 (32%), Positives = 70/179 (39%), Gaps = 35/179 (19%)
Query: 819 GYYGFGPTGCQA-CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP----- 872
G G G + CQC H A +C CR G C+ C+ +P
Sbjct: 144 GQAGLAAAGLRGRCQC-HGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPAT 202
Query: 873 -----SCRPCVCNGHADECNTHT-----------GACLGCRDHTGGEHCERCIAGFHGDP 916
C PC CN HA C ++ G C CR HT G HC C GF DP
Sbjct: 203 PRHPHPCLPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDP 262
Query: 917 RLPYGGQ--CRPCPC-PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGH 972
P + CR C C P G AT ++ S Q C C+ G TGL C C PG+
Sbjct: 263 SQPIFSRRACRACQCHPIG-------ATGGTCNQTSGQ--CTCKLGVTGLTCNRCGPGY 312
Score = 82.0 bits (201), Expect = 5e-15
Identities = 58/208 (27%), Positives = 80/208 (38%), Gaps = 38/208 (18%)
Query: 1012 HHTEGPHC----AHCKPGFHGQAARQSCH---RCTCNLLGTNPQQCPSPDQCHCDPSSGQ 1064
H T GP +H + F GQA + RC C+ P +CHC
Sbjct: 124 HSTPGPKATVAASHLRVEFGGQAGLAAAGLRGRCQCHGHAARCAARARPPRCHCRH---- 179
Query: 1065 CPCLPNVQGPSCDRCAPNF----WNLTSG---HGCQPCACHPSRARGPTCNEFT------ 1111
+ GP C+ C P+ W + H C PC+C+ R +E
Sbjct: 180 -----HTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCNQHARRCRFNSELFRLSGGR 234
Query: 1112 --GQCH-CRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGIDTPQCHRFTGHC 1162
G C CR GR C CQ W DP C AC C G C++ +G C
Sbjct: 235 SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRRACRACQCHPIGATGGTCNQTSGQC 294
Query: 1163 SCRPGVSGVRCDQCARGFSGIFPACHPC 1190
+C+ GV+G+ C++C G+ PC
Sbjct: 295 TCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 72.4 bits (176), Expect = 4e-12
Identities = 43/113 (38%), Positives = 51/113 (45%), Gaps = 16/113 (14%)
Query: 781 LPCQCNPQGS---LSSEC-----NPHGGQC-LCKPGVVGRRCDLCAPGYYG------FGP 825
LPC CN +SE GG C C+ GR C C PG++ F
Sbjct: 210 LPCSCNQHARRCRFNSELFRLSGGRSGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
Query: 826 TGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCR-PC 877
C+ACQC GA C +TSGQC C+ G GL C+RC G S R PC
Sbjct: 270 RACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGYQQSRSPRMPC 322
Score = 64.7 bits (156), Expect = 8e-10
Identities = 45/162 (27%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 421 GRCDSHDDPALGLVSGQ---CRCKEHVVGTRCQQCRDGFFG--------------LSISD 463
GRC H A + C C+ H G C+ CR L S
Sbjct: 155 GRCQCHGHAARCAARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSC 214
Query: 464 RLGCRRCQCNAR-GTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWGLSHDLL---- 517
RRC+ N+ + G + G C C+ GR C C PG W +
Sbjct: 215 NQHARRCRFNSELFRLSGGR----SGGVCERCRHHTAGRHCHYCQPGFWRDPSQPIFSRR 270
Query: 518 GCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGY 559
CR C C GA C++ +GQC C+ + G C + PGY
Sbjct: 271 ACRACQCHPIGATGGTCNQTSGQCTCKLGVTGLTCNRCGPGY 312
Score = 51.6 bits (122), Expect = 7e-06
Identities = 43/173 (24%), Positives = 59/173 (34%), Gaps = 44/173 (25%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGF--------GPTGCQACQCS 834
CQC+ + + +C C+ G C+ C P + + P C C C+
Sbjct: 157 CQCHGHAARCA-ARARPPRCHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPCSCN 215
Query: 835 HE---------------GALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPS------ 873
G +CE+ CR G C CQ G W PS
Sbjct: 216 QHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWRDPSQPIFSR 269
Query: 874 --CRPCVCN---GHADECNTHTGACLGCRDHTGGEHCERCIAGFH--GDPRLP 919
CR C C+ CN +G C C+ G C RC G+ PR+P
Sbjct: 270 RACRACQCHPIGATGGTCNQTSGQCT-CKLGVTGLTCNRCGPGYQQSRSPRMP 321
Score = 50.1 bits (118), Expect = 2e-05
Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 30/114 (26%)
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGH----W--GLSHDLLGCRPC 522
RCQC+ + P C+C+ TG GC+ C P H W C PC
Sbjct: 156 RCQCHGHAARCAARARPPR---CHCRHHTTGPGCESCRPSHRDWPWRPATPRHPHPCLPC 212
Query: 523 DCDV---------------GGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYFR 561
C+ GG C+ CR H GR C QPG++R
Sbjct: 213 SCNQHARRCRFNSELFRLSGGRSGGVCER------CRHHTAGRHCHYCQPGFWR 260
>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
Length = 1541
Score = 175 bits (443), Expect = 4e-43
Identities = 141/466 (30%), Positives = 177/466 (37%), Gaps = 102/466 (21%)
Query: 782 PCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGC-QACQCSHEGAL 839
PC C+ C+ G CLC+ G VG RC+ C G++G GC Q CQC H A
Sbjct: 872 PCNCSAG---HGSCDAISGLCLCEAGYVGPRCEQQCPQGHFG---PGCEQRCQCQHGAA- 924
Query: 840 SSLCEKTSGQCLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACL---- 894
C+ SG C C G G C+ C G +G C C A C+ G+CL
Sbjct: 925 ---CDHVSGACTCPAGWRGTFCEHACPAGFFGLDCRSACNCTAGA-ACDAVNGSCLCPAG 980
Query: 895 --------GCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQD 946
C HT G +C + A F+G P GQC P GP + + D
Sbjct: 981 RRGPRCAETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGD 1040
Query: 947 EYSQQIVCH-------------CRAGYTGLRCEA-CAPGHFGDPSRPGGRCQLCECSGNI 992
+C C G+ GL CE C P R G C
Sbjct: 1041 NCRHSCLCQNGGTCDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC--------- 1091
Query: 993 DPMDPDACDPHTGQCL------------RCLHHTEGPHCAH------------------C 1022
++ CDPHTG+CL CL G CA C
Sbjct: 1092 --LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQRCSCPPGAACHHVTGACRC 1149
Query: 1023 KPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCD-RCAP 1081
PGF G Q+C + QCP + C P++G C C GPSC RC P
Sbjct: 1150 PPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPA-CHPATGTCSCAAGYHGPSCQQRCPP 1208
Query: 1082 NFWNLTSGHGC-QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQ 1139
+ G GC Q C C G +C+ TG C C GF G C+ C + G G
Sbjct: 1209 GRY----GPGCEQLCGC----LNGGSCDAATGACRCPTGFLGTDCNLTCPQ---GRFGPN 1257
Query: 1140 C-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSGI 1183
C H C C C TG C C PG +GVRC++ C + G+
Sbjct: 1258 CTHVCGCGQGAA----CDPVTGTCLCPPGRAGVRCERGCPQNRFGV 1299
Score = 169 bits (429), Expect = 2e-41
Identities = 142/466 (30%), Positives = 174/466 (37%), Gaps = 139/466 (29%)
Query: 792 SSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQA-CQCSHEGALSSLCEKTSGQ 849
++ C+P G CLC PG VG RC D+C G+YG CQ C C+++G C +G
Sbjct: 792 AARCDPETGACLCLPGFVGSRCQDVCPAGWYG---PSCQTRCSCANDGH----CHPATGH 844
Query: 850 CLCRTGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERC 908
C C G G C R C G WG PC C+ C+ +G CL C
Sbjct: 845 CSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGHGSCDAISGLCL-------------C 891
Query: 909 IAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIV--------CHCRAGY 960
AG+ G PR CP+G HF C Q Q C C AG+
Sbjct: 892 EAGYVG-PRCEQ-------QCPQG-----HFGPGCEQRCQCQHGAACDHVSGACTCPAGW 938
Query: 961 TGLRCE-ACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCL----------- 1008
G CE AC G FG R C C+ ACD G CL
Sbjct: 939 RGTFCEHACPAGFFGLDCRSA-----CNCTAGA------ACDAVNGSCLCPAGRRGPRCA 987
Query: 1009 -RCLHHTEGPHCA------------------HCKPGFHGQAARQSC----------HRCT 1039
C HT G +C+ HC PG+ G + Q+C H C
Sbjct: 988 ETCPAHTYGHNCSQACACFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCL 1047
Query: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDR-CAPNFWNLTSGH--GCQPCA 1096
C GT CDP SG C C G +C++ C P H GC
Sbjct: 1048 CQNGGT------------CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGC---- 1091
Query: 1097 CHPSRARGPTCNEFTGQCHCRAGFGGRTC-SECQELHWGDPGLQCHACDCDSRGIDTPQC 1155
G C+ TG+C C AG+ G C S C +G+ Q C C C
Sbjct: 1092 -----LNGGLCDPHTGRCLCPAGWTGDKCQSPCLRGWFGEACAQ--RCSCPPGAA----C 1140
Query: 1156 HRFTGHCSCRPGVSGVRCDQ----------CAR--GFSGIFPACHP 1189
H TG C C PG +G C+Q CA+ G PACHP
Sbjct: 1141 HHVTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHP 1186
Score = 167 bits (424), Expect = 7e-41
Identities = 138/442 (31%), Positives = 173/442 (39%), Gaps = 90/442 (20%)
Query: 777 YNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGYYGFGPTGCQ-ACQCS 834
+N + C C S C+P GQC C PG +G C C G YG C+ +C C
Sbjct: 997 HNCSQACACFNGAS----CDPVHGQCHCAPGWMGPSCLQACPAGLYG---DNCRHSCLCQ 1049
Query: 835 HEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACL 894
+ G C+ SG C C G GL C++ + CR + C+ HTG CL
Sbjct: 1050 NGGT----CDPVSGHCACPEGWAGLACEKECLPRDVRAGCRHSGGCLNGGLCDPHTGRCL 1105
Query: 895 GCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVC 954
TG + C+ G+ G+ + C CP PG+ H T C
Sbjct: 1106 CPAGWTGDKCQSPCLRGWFGE------ACAQRCSCP--PGAACHHVTGA----------C 1147
Query: 955 HCRAGYTGLRCE-ACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHH 1013
C G+TG CE AC PG FG+ Q+C+C G + AC P TG C C
Sbjct: 1148 RCPPGFTGSGCEQACPPGSFGEDC-----AQMCQCPG-----ENPACHPATGTC-SCAAG 1196
Query: 1014 TEGPHCAH-CKPGFHGQAARQSCH--------------RCTCNLLGTN-----PQQCPSP 1053
GP C C PG +G Q C RC LGT+ PQ P
Sbjct: 1197 YHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDCNLTCPQGRFGP 1256
Query: 1054 DQCH---------CDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQ-PCACHPSRAR 1103
+ H CDP +G C C P G C+R P G GC+ C+C
Sbjct: 1257 NCTHVCGCGQGAACDPVTGTCLCPPGRAGVRCERGCPQN---RFGVGCEHTCSCR----N 1309
Query: 1104 GPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGH 1161
G C+ G C C G+ GR C C G G CH C C + C TG
Sbjct: 1310 GGLCHASNGSCSCGLGWTGRHCELACPP---GRYGAACHLECSCHNNST----CEPATGT 1362
Query: 1162 CSCRPGVSGVRCDQ-CARGFSG 1182
C C PG G C+ C GF G
Sbjct: 1363 CRCGPGFYGQACEHPCPPGFHG 1384
Score = 159 bits (402), Expect = 2e-38
Identities = 131/415 (31%), Positives = 167/415 (40%), Gaps = 85/415 (20%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGCQACQCSHEGALSSL 842
C C +G C+ G CLC PG+ GR C L P + FGP + CQC S
Sbjct: 611 CNCANRG----RCHRLYGACLCDPGLYGRFCHLTCPP-WAFGPGCSEECQCVQPHTQS-- 663
Query: 843 CEKTSGQCLCRTGAFGLRCD-RCQRGQWGFPSC-RPCVCNGHADECNTHTGACLGCRDHT 900
C+K G C C+ G G RC C+ G +G P C + C C AC D
Sbjct: 664 CDKRDGSCSCKAGFRGERCQAECELGYFG-PGCWQACTCPVGV--------AC----DSV 710
Query: 901 GGEHCERCIAGFHGD------PRLPYGGQC-RPCPCPEGPGSQRHFATSCHQDEYSQQIV 953
GE +RC AGF G+ P +G C C C P CH
Sbjct: 711 SGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCGGAP---------CH----GVTGQ 757
Query: 954 CHCRAGYTGLRCEA-CAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLH 1012
C C G TG CEA C G +G + C C+ + CDP TG CL CL
Sbjct: 758 CRCPPGRTGEDCEADCPEGRWGLGCQE--ICPACQHAAR--------CDPETGACL-CLP 806
Query: 1013 HTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
G C C G++G + + RC+C + HC P++G C C P
Sbjct: 807 GFVGSRCQDVCPAGWYGPSCQT---RCSC------------ANDGHCHPATGHCSCAPGW 851
Query: 1072 QGPSCDR-CAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTC-SECQ 1129
G SC R C W H C A H S C+ +G C C AG+ G C +C
Sbjct: 852 TGFSCQRACDTGHWGPDCSHPCNCSAGHGS------CDAISGLCLCEAGYVGPRCEQQCP 905
Query: 1130 ELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ-CARGFSGI 1183
+ H+G PG + C C C +G C+C G G C+ C GF G+
Sbjct: 906 QGHFG-PGCE-QRCQCQHGA----ACDHVSGACTCPAGWRGTFCEHACPAGFFGL 954
Score = 156 bits (394), Expect = 2e-37
Identities = 136/444 (30%), Positives = 167/444 (37%), Gaps = 88/444 (19%)
Query: 762 SEACAPLLISLSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC-DLCAPGY 820
+E C P T N + C C G+ C+ G C C PGV G C D C GY
Sbjct: 552 NETCPP-----DTFGKNCSFSCSCQNGGT----CDSVTGACRCPPGVSGTNCEDGCPKGY 602
Query: 821 YGFGPTGC-QACQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-PSC-RPC 877
YG C + C C++ G C + G CLC G +G C W F P C C
Sbjct: 603 YG---KHCRKKCNCANRGR----CHRLYGACLCDPGLYGRFC-HLTCPPWAFGPGCSEEC 654
Query: 878 VC-NGHADECNTHTGACLGCRDHTGGEHCE-RCIAGFHGDPRLPYGGQCRPCPCPEGPGS 935
C H C+ G+C C+ GE C+ C G+ G G + C CP G
Sbjct: 655 QCVQPHTQSCDKRDGSC-SCKAGFRGERCQAECELGYFGP------GCWQACTCPVG--- 704
Query: 936 QRHFATSCHQDEYSQQIVCHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDP 994
+C D S + C AG+ G C + C G FG C C G
Sbjct: 705 -----VAC--DSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSS-----CSCGG---- 748
Query: 995 MDPDACDPHTGQCLRCLHHTEGPHC-AHCKPGFHGQAARQSCHRCTCNLLGTNPQQCPSP 1053
C TGQC RC G C A C G G ++ C C
Sbjct: 749 ---APCHGVTGQC-RCPPGRTGEDCEADCPEGRWGLGCQEICPAC--------------Q 790
Query: 1054 DQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQP-CACHPSRARGPTCNEFTG 1112
CDP +G C CLP G C P W G CQ C+C A C+ TG
Sbjct: 791 HAARCDPETGACLCLPGFVGSRCQDVCPAGW---YGPSCQTRCSC----ANDGHCHPATG 843
Query: 1113 QCHCRAGFGGRTCSE-CQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSG 1170
C C G+ G +C C HWG C H C+C + C +G C C G G
Sbjct: 844 HCSCAPGWTGFSCQRACDTGHWGP---DCSHPCNCSA---GHGSCDAISGLCLCEAGYVG 897
Query: 1171 VRCD-QCARGFSGIFPACHPCHAC 1193
RC+ QC +G G P C C
Sbjct: 898 PRCEQQCPQGHFG--PGCEQRCQC 919
Score = 156 bits (394), Expect = 2e-37
Identities = 137/447 (30%), Positives = 164/447 (36%), Gaps = 102/447 (22%)
Query: 795 CNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCR 853
C+PH G+CLC G G +C C G+ FG Q C C A C +G C C
Sbjct: 1097 CDPHTGRCLCPAGWTGDKCQSPCLRGW--FGEACAQRCSCPPGAA----CHHVTGACRCP 1150
Query: 854 TGAFGLRCDR-CQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGF 912
G G C++ C G +G + C C G C+ TG C C AG+
Sbjct: 1151 PGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACHPATGTC-------------SCAAGY 1197
Query: 913 HG---DPRLP---YGGQCRP-CPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRC 965
HG R P YG C C C G AT C C G+ G C
Sbjct: 1198 HGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDA--ATGA----------CRCPTGFLGTDC 1245
Query: 966 E-ACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCL------------RCLH 1012
C G FG +C C ACDP TG CL C
Sbjct: 1246 NLTCPQGRFGPNCT-----HVCGCGQGA------ACDPVTGTCLCPPGRAGVRCERGCPQ 1294
Query: 1013 HTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGTNPQ------------QCPSPDQCH--- 1057
+ G C H +G S C+C L T C CH
Sbjct: 1295 NRFGVGCEHTCSCRNGGLCHASNGSCSCGLGWTGRHCELACPPGRYGAACHLECSCHNNS 1354
Query: 1058 -CDPSSGQCPCLPNVQGPSCDR-CAPNFWNLTSGHGCQP-CACHPSRARGPTCNEFTGQC 1114
C+P++G C C P G +C+ C P F G GCQ C C G C+ +G+C
Sbjct: 1355 TCEPATGTCRCGPGFYGQACEHPCPPGF----HGAGCQGLCWCQ----HGAPCDPISGRC 1406
Query: 1115 HCRAGFGGRTCSE-CQELHWGDPGLQCHA-CDCDSRGIDTPQCHRFTGHCSCRPGVSGVR 1172
C AGF G C C+ G G CH CDCD C TG C C PG SG
Sbjct: 1407 LCPAGFHGHFCERGCEP---GSFGEGCHQRCDCDGGA----PCDPVTGLCLCPPGRSGAT 1459
Query: 1173 CD-QCARGFSGIFPACHPCHACFGDWD 1198
C+ C RG G P+C C G D
Sbjct: 1460 CNLDCRRGQFG--PSCTLHCDCGGGAD 1484
Score = 151 bits (381), Expect = 6e-36
Identities = 120/379 (31%), Positives = 146/379 (38%), Gaps = 82/379 (21%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDL-CAPGYYGFGPTGC-QACQCSHEGALS 840
CQC + + C+P G C C G G C C PG YG GC Q C C + G+
Sbjct: 1175 CQCPGE---NPACHPATGTCSCAAGYHGPSCQQRCPPGRYG---PGCEQLCGCLNGGS-- 1226
Query: 841 SLCEKTSGQCLCRTGAFGLRCD-RCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDH 899
C+ +G C C TG G C+ C +G++G P+C G C+ TG CL C
Sbjct: 1227 --CDAATGACRCPTGFLGTDCNLTCPQGRFG-PNCTHVCGCGQGAACDPVTGTCL-CPPG 1282
Query: 900 TGGEHCERCIAGFHGDPRLPYGGQCR-PCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRA 958
G CER G P+ +G C C C G CH S C C
Sbjct: 1283 RAGVRCER------GCPQNRFGVGCEHTCSCRNGG--------LCHASNGS----CSCGL 1324
Query: 959 GYTGLRCEACAPGHFGDPSRPGGRCQL-CECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
G+TG CE P P R G C L C C N C+P TG C RC G
Sbjct: 1325 GWTGRHCELACP-----PGRYGAACHLECSCHNN------STCEPATGTC-RCGPGFYGQ 1372
Query: 1018 HCAH-CKPGFHGQAARQSCH------------RCTCNL--------LGTNP--------Q 1048
C H C PGFHG + C RC C G P Q
Sbjct: 1373 ACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCLCPAGFHGHFCERGCEPGSFGEGCHQ 1432
Query: 1049 QCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCN 1108
+C CDP +G C C P G +C+ + G C H G C+
Sbjct: 1433 RCDCDGGAPCDPVTGLCLCPPGRSGATCNL------DCRRGQFGPSCTLHCDCGGGADCD 1486
Query: 1109 EFTGQCHCRAGFGGRTCSE 1127
+GQCHC G+ G TC E
Sbjct: 1487 PVSGQCHCVDGYMGPTCRE 1505
Score = 90.1 bits (222), Expect = 2e-17
Identities = 81/288 (28%), Positives = 107/288 (37%), Gaps = 80/288 (27%)
Query: 954 CHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLH 1012
C C G+TGL C E C P FG CS + + CD TG C RC
Sbjct: 540 CDCPEGWTGLICNETCPPDTFGK-----------NCSFSCSCQNGGTCDSVTGAC-RCPP 587
Query: 1013 HTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNV 1071
G +C C G++G+ R+ C+ C + +CH G C C P +
Sbjct: 588 GVSGTNCEDGCPKGYYGKHCRKKCN-------------CANRGRCH--RLYGACLCDPGL 632
Query: 1072 QGPSCDRCAPNFWNLTSGHGC-QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTC-SECQ 1129
G C P + G GC + C C + +C++ G C C+AGF G C +EC+
Sbjct: 633 YGRFCHLTCPPW---AFGPGCSEECQCVQPHTQ--SCDKRDGSCSCKAGFRGERCQAECE 687
Query: 1130 ELHWGDPGLQCHACD----CDS-------------RGIDTPQ------------------ 1154
++G Q C CDS +G D Q
Sbjct: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSCG 747
Query: 1155 ---CHRFTGHCSCRPGVSGVRCD-QCARGFSG-----IFPACHPCHAC 1193
CH TG C C PG +G C+ C G G I PAC C
Sbjct: 748 GAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGLGCQEICPACQHAARC 795
Score = 82.0 bits (201), Expect = 5e-15
Identities = 85/282 (30%), Positives = 103/282 (36%), Gaps = 66/282 (23%)
Query: 308 GACICKHNTRGLNCE-QCQDFYRD--------LPWRPAEDGHSHAC-RKCECHGHTHSCH 357
G+C CK RG C+ +C+ Y P A D S C ++C C
Sbjct: 669 GSCSCKAGFRGERCQAECELGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCG 728
Query: 358 FDMAVYLASGNVS------GGVCDG------CQHNTAGRHCELCRPFFYRDPTKDLRDPA 405
+ V N S G C G C G CE P + L
Sbjct: 729 QECPVGTFGVNCSSSCSCGGAPCHGVTGQCRCPPGRTGEDCEADCP----EGRWGLGCQE 784
Query: 406 VCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDR 464
+C +C Q RCD +G C C VG+RCQ C G++G S R
Sbjct: 785 ICPAC-------QHAARCDPE--------TGACLCLPGFVGSRCQDVCPAGWYGPSCQTR 829
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWG--LSHDLLGCRP 521
C C G C P +G C C TG C R C GHWG SH P
Sbjct: 830 -----CSCANDGH------CHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSH------P 872
Query: 522 CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP-GYFRP 562
C+C G CD +G C C VG RCEQ P G+F P
Sbjct: 873 CNCSAGHG---SCDAISGLCLCEAGYVGPRCEQQCPQGHFGP 911
Score = 81.3 bits (199), Expect = 8e-15
Identities = 85/301 (28%), Positives = 106/301 (35%), Gaps = 80/301 (26%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C G + C P V G C+C G+ CE R P G H
Sbjct: 1262 CGC-GQGAACDP-----------VTGTCLCPPGRAGVRCE------RGCPQNRFGVGCEH 1303
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCEL-CRPFFYRDPTK-- 399
C C G H+ S G C C GRHCEL C P Y
Sbjct: 1304 TC-SCRNGGLCHA--------------SNGSCS-CGLGWTGRHCELACPPGRYGAACHLE 1347
Query: 400 -DLRDPAVCR----SCDCDP---------------MGSQDGGRCDSHDDPALGLVSGQCR 439
+ + C +C C P G+ G C +SG+C
Sbjct: 1348 CSCHNNSTCEPATGTCRCGPGFYGQACEHPCPPGFHGAGCQGLCWCQHGAPCDPISGRCL 1407
Query: 440 CKEHVVGTRCQQ-CRDGFFGLSISDRLGC-RRCQCNARGTVPGSTPCDPNSGSCYCKRLV 497
C G C++ C G FG GC +RC C+ G PCDP +G C C
Sbjct: 1408 CPAGFHGHFCERGCEPGSFGE------GCHQRCDCD------GGAPCDPVTGLCLCPPGR 1455
Query: 498 TGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQ 556
+G C+ C G +G S L CD GG D CD +GQCHC +G C +
Sbjct: 1456 SGATCNLDCRRGQFGPSCTL------HCDCGGGAD--CDPVSGQCHCVDGYMGPTCREGG 1507
Query: 557 P 557
P
Sbjct: 1508 P 1508
Score = 79.3 bits (194), Expect = 3e-14
Identities = 87/313 (27%), Positives = 112/313 (35%), Gaps = 87/313 (27%)
Query: 290 SECAPAPGAPAHAEGMVHGACICKHNTRGLNC-EQCQDFYRDLPWRPAEDGHSHACRKCE 348
S C GA A V+G+C+C RG C E C PA + + C
Sbjct: 958 SACNCTAGAACDA---VNGSCLCPAGRRGPRCAETC----------PAHTYGHNCSQACA 1004
Query: 349 C---------HGHTH--------SCHFDMAVYLASGNV-------SGGVCD------GCQ 378
C HG H SC L N +GG CD C
Sbjct: 1005 CFNGASCDPVHGQCHCAPGWMGPSCLQACPAGLYGDNCRHSCLCQNGGTCDPVSGHCACP 1064
Query: 379 HNTAGRHCEL-CRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQ 437
AG CE C P +D+R A CR G +GG CD H +G+
Sbjct: 1065 EGWAGLACEKECLP-------RDVR--AGCRHSG----GCLNGGLCDPH--------TGR 1103
Query: 438 CRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRL 496
C C G +CQ C G+FG + + R C P C +G+C C
Sbjct: 1104 CLCPAGWTGDKCQSPCLRGWFGEACAQRCSC-----------PPGAACHHVTGACRCPPG 1152
Query: 497 VTGRGCDR-CLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ- 554
TG GC++ C PG +G + C C +P C TG C C G C+Q
Sbjct: 1153 FTGSGCEQACPPGSFGED----CAQMCQCP---GENPACHPATGTCSCAAGYHGPSCQQR 1205
Query: 555 VQPGYFRPFLDHL 567
PG + P + L
Sbjct: 1206 CPPGRYGPGCEQL 1218
Score = 77.8 bits (190), Expect = 9e-14
Identities = 84/307 (27%), Positives = 102/307 (33%), Gaps = 69/307 (22%)
Query: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQC---QDFYRDLPWRPAEDGHSHACR 345
A C+ PGA H V GAC C G CEQ F D G + AC
Sbjct: 1129 AQRCSCPPGAACHH---VTGACRCPPGFTGSGCEQACPPGSFGEDCAQMCQCPGENPACH 1185
Query: 346 K----CECHGHTH--SCH-------FDMAVYLASGNVSGGVCDG------CQHNTAGRHC 386
C C H SC + G ++GG CD C G C
Sbjct: 1186 PATGTCSCAAGYHGPSCQQRCPPGRYGPGCEQLCGCLNGGSCDAATGACRCPTGFLGTDC 1245
Query: 387 ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVG 446
L P + P C C G CD V+G C C G
Sbjct: 1246 NLTCP-------QGRFGPNCTHVCGCG-----QGAACDP--------VTGTCLCPPGRAG 1285
Query: 447 TRCQQ-CRDGFFGLSISDRLGCRR-CQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD- 503
RC++ C FG+ GC C C G C ++GSC C TGR C+
Sbjct: 1286 VRCERGCPQNRFGV------GCEHTCSCRNGGL------CHASNGSCSCGLGWTGRHCEL 1333
Query: 504 RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQ-VQPGYFRP 562
C PG +G + L C C C+ TG C C G+ CE PG+
Sbjct: 1334 ACPPGRYGAACHL----ECSCHNNST----CEPATGTCRCGPGFYGQACEHPCPPGFHGA 1385
Query: 563 FLDHLIW 569
L W
Sbjct: 1386 GCQGLCW 1392
Score = 75.5 bits (184), Expect = 4e-13
Identities = 80/277 (28%), Positives = 100/277 (36%), Gaps = 51/277 (18%)
Query: 306 VHGACICKHNTRGLNCEQ-CQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHFDMAVYL 364
V GAC C G NCE C Y H +KC C + CH L
Sbjct: 579 VTGACRCPPGVSGTNCEDGCPKGYYG----------KHCRKKCNC-ANRGRCHRLYGACL 627
Query: 365 ASGNVSGGVCD-GCQHNTAGRHC-ELCRPFFYRDPTKDLRDPAV-CRS----------CD 411
+ G C C G C E C+ + D RD + C++ C+
Sbjct: 628 CDPGLYGRFCHLTCPPWAFGPGCSEECQCVQPHTQSCDKRDGSCSCKAGFRGERCQAECE 687
Query: 412 CDPMGSQDGGRCDSHDDPALGLVSGQC--RCKEHVVGTRC-QQCRDGFFGLSISDRLGCR 468
G C A VSG+C RC G C Q+C G FG++ S C
Sbjct: 688 LGYFGPGCWQACTCPVGVACDSVSGECGKRCPAGFQGEDCGQECPVGTFGVNCSSSCSC- 746
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGLSHDLLGCRP-CDCDV 526
G PC +G C C TG C+ C G WGL GC+ C
Sbjct: 747 -----------GGAPCHGVTGQCRCPPGRTGEDCEADCPEGRWGL-----GCQEICPACQ 790
Query: 527 GGALDPQCDEGTGQCHCRQHMVGRRCEQVQP-GYFRP 562
A +CD TG C C VG RC+ V P G++ P
Sbjct: 791 HAA---RCDPETGACLCLPGFVGSRCQDVCPAGWYGP 824
Score = 75.1 bits (183), Expect = 6e-13
Identities = 86/300 (28%), Positives = 104/300 (34%), Gaps = 76/300 (25%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGAC--ICKHNTRGLNCE-QCQDFYRDLPWRPAEDG 339
C HA+ C P GA G V C +C G +C+ +C A DG
Sbjct: 786 CPACQHAARCDPETGACLCLPGFVGSRCQDVCPAGWYGPSCQTRCSC---------ANDG 836
Query: 340 HSH-ACRKCECH--------------GH-----THSCHFDMAVYLASGNVSGGVCDGCQH 379
H H A C C GH +H C+ S + G+C C+
Sbjct: 837 HCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCSHPCNCSAGH--GSCDAISGLCL-CEA 893
Query: 380 NTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR 439
G CE P + P + R C C Q G CD VSG C
Sbjct: 894 GYVGPRCEQQCPQGHFGPGCEQR-------CQC-----QHGAACDH--------VSGACT 933
Query: 440 CKEHVVGTRCQQ-CRDGFFGLSISDRLGCRR-CQCNARGTVPGSTPCDPNSGSCYCKRLV 497
C GT C+ C GFFGL CR C C A CD +GSC C
Sbjct: 934 CPAGWRGTFCEHACPAGFFGLD------CRSACNCTA------GAACDAVNGSCLCPAGR 981
Query: 498 TGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
G C P H H+ + C C G + CD GQCHC +G C Q P
Sbjct: 982 RGPRCAETCPAH-TYGHNC--SQACACFNGAS----CDPVHGQCHCAPGWMGPSCLQACP 1034
Score = 68.2 bits (165), Expect = 7e-11
Identities = 64/204 (31%), Positives = 80/204 (39%), Gaps = 50/204 (24%)
Query: 370 SGGVC----DGCQ--HNTAGRHC-ELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGR 422
+GG C DGC G C E C P D SC C Q+GG
Sbjct: 529 NGGTCLLGLDGCDCPEGWTGLICNETCPP--------DTFGKNCSFSCSC-----QNGGT 575
Query: 423 CDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCR-RCQCNARGTVPG 480
CDS V+G CRC V GT C+ C G++G CR +C C RG
Sbjct: 576 CDS--------VTGACRCPPGVSGTNCEDGCPKGYYGKH------CRKKCNCANRGR--- 618
Query: 481 STPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTG 539
C G+C C + GR C C P +G GC +C CD+ G
Sbjct: 619 ---CHRLYGACLCDPGLYGRFCHLTCPPWAFG-----PGCSE-ECQCVQPHTQSCDKRDG 669
Query: 540 QCHCRQHMVGRRCE-QVQPGYFRP 562
C C+ G RC+ + + GYF P
Sbjct: 670 SCSCKAGFRGERCQAECELGYFGP 693
Score = 68.2 bits (165), Expect = 7e-11
Identities = 72/268 (26%), Positives = 88/268 (32%), Gaps = 66/268 (24%)
Query: 312 CKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSCHF-------DMAVYL 364
C T G+NC S +C CHG T C D
Sbjct: 731 CPVGTFGVNCSS-----------------SCSCGGAPCHGVTGQCRCPPGRTGEDCEADC 773
Query: 365 ASGNVSGG---VCDGCQHNTAGRHCE------LCRPFFYRDPTKDLRDPAVCRSCDCDPM 415
G G +C CQH C+ LC P F +D+ C
Sbjct: 774 PEGRWGLGCQEICPACQH---AARCDPETGACLCLPGFVGSRCQDV--------CPAGWY 822
Query: 416 GSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNA 474
G RC +D +G C C G CQ+ C G +G S C C+A
Sbjct: 823 GPSCQTRCSCANDGHCHPATGHCSCAPGWTGFSCQRACDTGHWGPDCS-----HPCNCSA 877
Query: 475 RGTVPGSTPCDPNSGSCYCKRLVTGRGCDR-CLPGHWGLSHDLLGCRP-CDCDVGGALDP 532
G CD SG C C+ G C++ C GH+G GC C C G A
Sbjct: 878 -----GHGSCDAISGLCLCEAGYVGPRCEQQCPQGHFGP-----GCEQRCQCQHGAA--- 924
Query: 533 QCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
CD +G C C G CE P F
Sbjct: 925 -CDHVSGACTCPAGWRGTFCEHACPAGF 951
Score = 62.4 bits (150), Expect = 4e-09
Identities = 127/511 (24%), Positives = 151/511 (29%), Gaps = 122/511 (23%)
Query: 762 SEACAPLLISLSTLIYNGALPCQCNP--QGSLSS----ECNPHGGQCL------------ 803
+E A L + A PC C P QG EC H G C
Sbjct: 126 AECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCVNTPGSYLC 185
Query: 804 -CKPG----VVGRRCDLCAPGYYGFGPTGCQ-----------ACQCSHEGALS------- 840
CKPG R C A G GCQ CQC L
Sbjct: 186 ECKPGFRLHTDSRTC--LAINSCALGNGGCQHHCVQLTITRHRCQCRPGFQLQEDGRHCV 243
Query: 841 --SLCEKTSGQCLCRTGAF-GLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGACL-GC 896
S C +G C+ R GL C G + C DEC C GC
Sbjct: 244 RRSPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACE---DVDECAAGLAQCAHGC 300
Query: 897 RDHTGGEHCERCIAGFH--GDPRLPY-------------GGQCRP----------CPCPE 931
+ G C C AG+ D R Y G C C CP
Sbjct: 301 LNTQGSFKCV-CHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPR 359
Query: 932 GPGSQRHFATSCHQDEYSQQIVCH--CRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECS 989
G T D+ + C C G C C G+ S G C+
Sbjct: 360 GYELDTDQRTCIDVDDCADSPCCQQVCTNNPGGYEC-GCYAGY--RLSADGCGCE----- 411
Query: 990 GNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSC---HRCTCNLLGTN 1046
D D C G C + G C+ G+ R+ C +L G
Sbjct: 412 ------DVDECASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEEPMVDLDGEL 465
Query: 1047 PQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNF---WNLTS---------GHGCQP 1094
P P P H + P L D LT GH C
Sbjct: 466 PFVRPLP---HIAVLQDELPQLFQDDDVGADEEEAELRGEHTLTEKFVCLDDSFGHDCS- 521
Query: 1095 CACHPSRARGPTCNEFTGQCHCRAGFGGRTCSE-CQELHWGDPGLQC-HACDCDSRGIDT 1152
C R G TC C C G+ G C+E C +G C +C C + G
Sbjct: 522 LTCDDCR-NGGTCLLGLDGCDCPEGWTGLICNETCPPDTFGK---NCSFSCSCQNGG--- 574
Query: 1153 PQCHRFTGHCSCRPGVSGVRC-DQCARGFSG 1182
C TG C C PGVSG C D C +G+ G
Sbjct: 575 -TCDSVTGACRCPPGVSGTNCEDGCPKGYYG 604
Score = 59.7 bits (143), Expect = 2e-08
Identities = 102/401 (25%), Positives = 130/401 (32%), Gaps = 115/401 (28%)
Query: 784 QCNPQGSLSSECNP----HGGQCL--------CKPGVVGRRCDLCAPGYYGFGPTGCQAC 831
Q + +G LS+EC+ HGG+C+ C PG G RC + C+
Sbjct: 117 QPDEEGCLSAECSASLCFHGGRCVPGSAQPCHCPPGFQGPRCQ--------YDVDECR-- 166
Query: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTG 891
+H G C T G LC C+ G R C+ + C G
Sbjct: 167 --THNGGCQHRCVNTPGSYLC----------ECKPGFRLHTDSRTCLA---INSCALGNG 211
Query: 892 ACL-GCRDHTGGEHCERCIAGFHGDPRLPYGGQC-RPCPCPEGPGSQRHFATSCHQDEYS 949
C C T H +C GF G C R PC GS H
Sbjct: 212 GCQHHCVQLTITRHRCQCRPGFQLQED---GRHCVRRSPCANRNGSCMHRC--------- 259
Query: 950 QQIV-----CHCRAGY----TGLRCE---ACAPG-------------------HFGDPSR 978
Q+V C C GY G CE CA G H G
Sbjct: 260 -QVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELG 318
Query: 979 PGGRCQLCECSGNIDPMDPDACDPHTGQCLR-CLHHTEGPHCAHCKPGFHGQAARQSCHR 1037
GR +C I+ ++C+ + G C C H + GP C C G+
Sbjct: 319 ADGR----QCY-RIEMEIVNSCEANNGGCSHGCSHTSAGPLCT-CPRGYE---------- 362
Query: 1038 CTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQPC-A 1096
L T+ + C D C P Q C N G C C + G GC+
Sbjct: 363 -----LDTDQRTCIDVDDCADSPCCQQV-CTNNPGGYECG-CYAGYRLSADGCGCEDVDE 415
Query: 1097 CHPSRAR-GPTCNEFTG--QCHCRAGF----GGRTCSECQE 1130
C SR C G QC C AG+ R CS +E
Sbjct: 416 CASSRGGCEHHCTNLAGSFQCSCEAGYRLHEDRRGCSPLEE 456
Score = 58.5 bits (140), Expect = 6e-08
Identities = 99/387 (25%), Positives = 127/387 (32%), Gaps = 88/387 (22%)
Query: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCV----CNGHADECN 887
Q EG LS+ C + LC G RC G C P C DEC
Sbjct: 117 QPDEEGCLSAECSAS----LCFHGG------RCVPGSAQPCHCPPGFQGPRCQYDVDECR 166
Query: 888 THTGACLGCRDHTGGEHCERCIAGF--HGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQ 945
TH G C +T G + C GF H D R C G G Q H C Q
Sbjct: 167 THNGGCQHRCVNTPGSYLCECKPGFRLHTDSRTCLA--INSCALGNG-GCQHH----CVQ 219
Query: 946 DEYSQQIVCHCRAGY----TGLRCEACAPGHFGDPSRPGG---RCQL------CECSGNI 992
++ C CR G+ G C +P +R G RCQ+ CEC
Sbjct: 220 LTITRH-RCQCRPGFQLQEDGRHCVRRSP----CANRNGSCMHRCQVVRGLARCECHVGY 274
Query: 993 DPM-------DPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCTCNLLGT 1045
D D C QC +T+G C G+ A + C+R ++ +
Sbjct: 275 QLAADGKACEDVDECAAGLAQCAHGCLNTQGSFKCVCHAGYELGADGRQCYRIEMEIVNS 334
Query: 1046 NPQQCPSPDQCHCDPSSGQCP--CLPNVQGPSCDRCAPNFWNLTSGHGC---QPCACHPS 1100
C+ ++G C C GP C C + T C CA P
Sbjct: 335 ------------CEANNGGCSHGCSHTSAGPLC-TCPRGYELDTDQRTCIDVDDCADSPC 381
Query: 1101 RARGPTCNEFTGQCHCRAGF----GGRTCSECQELHWGDPGLQCHACDCDSRGIDTPQCH 1156
+ T N +C C AG+ G C + E SRG C
Sbjct: 382 CQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDEC-------------ASSRGGCEHHCT 428
Query: 1157 RFTG--HCSCRPGVSGVRCDQCARGFS 1181
G CSC +G R + RG S
Sbjct: 429 NLAGSFQCSCE---AGYRLHEDRRGCS 452
Score = 35.0 bits (79), Expect = 0.66
Identities = 33/116 (28%), Positives = 42/116 (36%), Gaps = 20/116 (17%)
Query: 463 DRLGCRRCQCNARGTVPGSTPCDPNSGS-CYCKRLVTGRGC----DRCLPGHWGLSHDLL 517
D GC +C+A G C P S C+C G C D C + G H +
Sbjct: 119 DEEGCLSAECSASLCFHGGR-CVPGSAQPCHCPPGFQGPRCQYDVDECRTHNGGCQHRCV 177
Query: 518 ---GCRPCDCDVGGALDP---------QCDEGTGQC--HCRQHMVGRRCEQVQPGY 559
G C+C G L C G G C HC Q + R Q +PG+
Sbjct: 178 NTPGSYLCECKPGFRLHTDSRTCLAINSCALGNGGCQHHCVQLTITRHRCQCRPGF 233
Score = 32.0 bits (71), Expect = 5.6
Identities = 49/212 (23%), Positives = 73/212 (34%), Gaps = 40/212 (18%)
Query: 290 SECAPAPGAPAHAEGMVHGACICKHNTR------GLNCEQCQDFYRDLPWRPAEDGHSHA 343
S CA G+ H +V G C+ + G CE + L ++
Sbjct: 246 SPCANRNGSCMHRCQVVRGLARCECHVGYQLAADGKACEDVDECAAGLAQCAHGCLNTQG 305
Query: 344 CRKCECHG------HTHSCH-FDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRD 396
KC CH C+ +M + + +GG GC H +AG C R +
Sbjct: 306 SFKCVCHAGYELGADGRQCYRIEMEIVNSCEANNGGCSHGCSHTSAGPLCTCPRGYELDT 365
Query: 397 PTK------DLRDPAVCRS-CDCDPMG-----------SQDGGRCDSHDDPALGLVSGQC 438
+ D D C+ C +P G S DG C+ D+ A S +
Sbjct: 366 DQRTCIDVDDCADSPCCQQVCTNNPGGYECGCYAGYRLSADGCGCEDVDECA----SSRG 421
Query: 439 RCKEH---VVGTRCQQCRDGFFGLSISDRLGC 467
C+ H + G+ C G+ DR GC
Sbjct: 422 GCEHHCTNLAGSFQCSCEAGY--RLHEDRRGC 451
>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
sapiens]
Length = 1037
Score = 162 bits (409), Expect = 4e-39
Identities = 142/449 (31%), Positives = 177/449 (39%), Gaps = 88/449 (19%)
Query: 783 CQCNPQGSLSSECNPHGGQCLCKPGVVGRRCD--LCAPGYYGFGPTGCQA-CQCSHEGAL 839
C C P + C P G CLC+ G G RC LC G+YG CQA C C E +L
Sbjct: 319 CDCAPD----ARCFPANGACLCEHGFTGDRCTDRLCPDGFYGLS---CQAPCTCDREHSL 371
Query: 840 SSLCEKTSGQCLCRTGAFGLRC-DRCQRGQWGFPSCRP-CVCNGHADECNTHTGACLGCR 897
S C +G+C C G GL C + C + G P C+ C+C H C +G C
Sbjct: 372 S--CHPMNGECSCLPGWAGLHCNESCPQDTHG-PGCQEHCLCL-HGGVCQATSGLCQCAP 427
Query: 898 DHTGGE------------------HCERCIA--GFHGDPRLPYGGQCRPC--PCPEGP-G 934
+TG CE IA G+ G Q C PCP G G
Sbjct: 428 GYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCPPGTWG 487
Query: 935 SQRHFATSC-HQDEYSQQI-VCHCRAGYTGLRCE-ACAPGHFGDPSRPGGRCQLCECSGN 991
+ + C H+ S Q C C G+ G C+ C G FG+ G C+C +
Sbjct: 488 FSCNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFGE-----GCASRCDCDHS 542
Query: 992 IDPMDPDACDPHTGQCLRCLHHTEGPHC-AHCKPGFHGQAARQSCHRCTCNLLGTNPQQC 1050
D CDP G+C +C G C C G G + CTC GT
Sbjct: 543 ------DGCDPVHGRC-QCQAGWMGARCHLSCPEGLWGV---NCSNTCTCKNGGT----- 587
Query: 1051 PSPDQCHCDPSSGQCPCLPNVQGPSCDR-CAPNFWNLTSGHGCQPCACHPSRARGPTCNE 1109
C P +G C C P +GPSC R C P + G C PC C A C+
Sbjct: 588 -------CLPENGNCVCAPGFRGPSCQRSCQPGRY----GKRCVPCKC----ANHSFCHP 632
Query: 1110 FTGQCHCRAGFGGRTCSE-CQELHWGDPGLQCHACDCDSRGIDTPQCHRFTGHCSCRPGV 1168
G C+C AG+ G CS+ C HWG+ Q C C G CH G C C G
Sbjct: 633 SNGTCYCLAGWTGPDCSQPCPPGHWGENCAQ--TCQCHHGG----TCHPQDGSCICPLGW 686
Query: 1169 SGVRC-DQCARGFSGIFPACHPCHACFGD 1196
+G C + C G G PC G+
Sbjct: 687 TGHHCLEGCPLGTFGA-NCSQPCQCGPGE 714
Score = 144 bits (363), Expect = 8e-34
Identities = 140/451 (31%), Positives = 176/451 (39%), Gaps = 108/451 (23%)
Query: 801 QCLCKPGVVGRRCDL-CAPGYYGFGPTGCQACQCSHEGALSSLCEKTSGQCLCRTGAFGL 859
QC C PG G C CAPG +G P + C C + +S C+ SG C C +G
Sbjct: 119 QCQCVPGWRGDDCSSECAPGMWG--PQCDKPCSCGN----NSSCDPKSGVCSCPSGLQPP 172
Query: 860 RC-DRCQRGQWGFPSCRPCVCNGHADECNTHTGACLGCRDHTGGE---HCERCIAGFH-- 913
C C G +G P+C+ C H C+ TGAC + TG C + +GF
Sbjct: 173 NCLQPCTPGYYG-PACQ-FRCQCHGAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCP 230
Query: 914 --------GDPRLPYGG-QCRP--------CPCPEG-PGSQRHFATSCHQ----DEYSQQ 951
G + P G C P PCPEG G CH D ++ Q
Sbjct: 231 STHSCQNGGVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQ 290
Query: 952 IVCHCRAGYTGLRC-EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDA-CDPHTGQCLR 1009
C C GYTG RC E C G FG + C+C+ PDA C P G CL
Sbjct: 291 --CRCAPGYTGDRCREECPVGRFGQDC-----AETCDCA-------PDARCFPANGACL- 335
Query: 1010 CLHHTEGPHCAH--CKPGFHGQAARQ----------SCH----RCTCNLLGTNPQQC--P 1051
C H G C C GF+G + + SCH C+C L G C
Sbjct: 336 CEHGFTGDRCTDRLCPDGFYGLSCQAPCTCDREHSLSCHPMNGECSC-LPGWAGLHCNES 394
Query: 1052 SPDQCH---------------CDPSSGQCPCLPNVQGPSC-DRCAPNFWNLTSGHGCQP- 1094
P H C +SG C C P GP C C P+ T G C
Sbjct: 395 CPQDTHGPGCQEHCLCLHGGVCQATSGLCQCAPGYTGPHCASLCPPD----TYGVNCSAR 450
Query: 1095 CACHPSRARGPTCNEFTGQCHCRAGFGGRTCS-ECQELHWGDPGLQCHA-CDCDSRGIDT 1152
C+C + A C+ G+C C+ G+ CS C W G C+A C C + +
Sbjct: 451 CSCENAIA----CSPIDGECVCKEGWQRGNCSVPCPPGTW---GFSCNASCQCAHEAVCS 503
Query: 1153 PQCHRFTGHCSCRPGVSGVRCD-QCARGFSG 1182
PQ TG C+C PG G C C +G G
Sbjct: 504 PQ----TGACTCTPGWHGAHCQLPCPKGQFG 530
Score = 99.0 bits (245), Expect = 4e-20
Identities = 85/255 (33%), Positives = 105/255 (41%), Gaps = 60/255 (23%)
Query: 954 CHCRAGYTGLRCEA-CAPGHFGDP-SRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
C C G+ G C + CAPG +G +P C C N +CDP +G C C
Sbjct: 120 CQCVPGWRGDDCSSECAPGMWGPQCDKP------CSCGNN------SSCDPKSGVC-SCP 166
Query: 1012 HHTEGPHCAH-CKPGFHGQAARQSCHRCTCNLLGTNPQQCPSPDQCH---CDPSSGQCPC 1067
+ P+C C PG++G A + C QCH CDP +G C C
Sbjct: 167 SGLQPPNCLQPCTPGYYGPACQFRC-------------------QCHGAPCDPQTGACFC 207
Query: 1068 LPNVQGPSCD-RCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCS 1126
GPSCD C+ TSG C + H S G G C C G+ G CS
Sbjct: 208 PAERTGPSCDVSCSQG----TSGFFCP--STH-SCQNGGVFQTPQGSCSCPPGWMGTICS 260
Query: 1127 -ECQELHWGDPGLQC-HACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRC-DQCARGFSGI 1183
C E G G C C C + G+ C RFTG C C PG +G RC ++C G G
Sbjct: 261 LPCPE---GFHGPNCSQECRCHNGGL----CDRFTGQCRCAPGYTGDRCREECPVGRFGQ 313
Query: 1184 FPA----CHPCHACF 1194
A C P CF
Sbjct: 314 DCAETCDCAPDARCF 328
Score = 75.1 bits (183), Expect = 6e-13
Identities = 72/255 (28%), Positives = 92/255 (36%), Gaps = 66/255 (25%)
Query: 306 VHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACR-KCECHGHTHSCHFDMAVYL 364
+ G C+CK + NC +P P G S C C+C H C
Sbjct: 462 IDGECVCKEGWQRGNCS--------VPCPPGTWGFS--CNASCQC-AHEAVC-------- 502
Query: 365 ASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCD 424
+ G C C G HC+L P K CDCD DG CD
Sbjct: 503 ---SPQTGACT-CTPGWHGAHCQLPCP-------KGQFGEGCASRCDCD---HSDG--CD 546
Query: 425 SHDDPALGLVSGQCRCKEHVVGTRCQ-QCRDGFFGLSISDRLGCRRCQCNARGTVPGSTP 483
V G+C+C+ +G RC C +G +G++ S+ C C GT
Sbjct: 547 P--------VHGRCQCQAGWMGARCHLSCPEGLWGVNCSN-----TCTCKNGGT------ 587
Query: 484 CDPNSGSCYCKRLVTGRGCDR-CLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCH 542
C P +G+C C G C R C PG +G C PC C A C G C+
Sbjct: 588 CLPENGNCVCAPGFRGPSCQRSCQPGRYGKR-----CVPCKC----ANHSFCHPSNGTCY 638
Query: 543 CRQHMVGRRCEQVQP 557
C G C Q P
Sbjct: 639 CLAGWTGPDCSQPCP 653
Score = 69.7 bits (169), Expect = 2e-11
Identities = 77/281 (27%), Positives = 100/281 (35%), Gaps = 50/281 (17%)
Query: 289 ASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDG-HSHACRK- 346
A C AP A +GAC+C+H G ++C D R DG + +C+
Sbjct: 316 AETCDCAPDARCFP---ANGACLCEHGFTG---DRCTD-------RLCPDGFYGLSCQAP 362
Query: 347 CEC-HGHTHSCHFDMAVYLASGNVSGGVC-DGCQHNTAGRHCE---LCRPFFYRDPTKDL 401
C C H+ SCH +G C + C +T G C+ LC T L
Sbjct: 363 CTCDREHSLSCHPMNGECSCLPGWAGLHCNESCPQDTHGPGCQEHCLCLHGGVCQATSGL 422
Query: 402 -------RDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQ-QCR 453
P C D G RC + A + G+C CKE C C
Sbjct: 423 CQCAPGYTGPHCASLCPPDTYGVNCSARCSCENAIACSPIDGECVCKEGWQRGNCSVPCP 482
Query: 454 DGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD-RCLPGHWGL 512
G +G S CNA C P +G+C C G C C G +G
Sbjct: 483 PGTWGFS-----------CNASCQCAHEAVCSPQTGACTCTPGWHGAHCQLPCPKGQFG- 530
Query: 513 SHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
GC CDCD CD G+C C+ +G RC
Sbjct: 531 ----EGCASRCDCDHSDG----CDPVHGRCQCQAGWMGARC 563
Score = 64.3 bits (155), Expect = 1e-09
Identities = 47/150 (31%), Positives = 65/150 (43%), Gaps = 35/150 (23%)
Query: 1049 QCPSPDQCHCDPSSGQCPCLPNVQGPSC-DRCAPNFWNLTSGHGC-QPCACHPSRARGPT 1106
+C +P+QC C+P +G C CAP W G C +PC+C +
Sbjct: 113 RCVAPNQCQ---------CVPGWRGDDCSSECAPGMW----GPQCDKPCSC----GNNSS 155
Query: 1107 CNEFTGQCHCRAGFGGRTCSE-CQELHWGDP---GLQCHACDCDSRGIDTPQCHRFTGHC 1162
C+ +G C C +G C + C ++G QCH CD PQ TG C
Sbjct: 156 CDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFRCQCHGAPCD------PQ----TGAC 205
Query: 1163 SCRPGVSGVRCD-QCARGFSGIF-PACHPC 1190
C +G CD C++G SG F P+ H C
Sbjct: 206 FCPAERTGPSCDVSCSQGTSGFFCPSTHSC 235
Score = 58.5 bits (140), Expect = 6e-08
Identities = 51/193 (26%), Positives = 66/193 (34%), Gaps = 61/193 (31%)
Query: 409 SCDCDP--MGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRC-QQCRDGFFGLSISDRL 465
S +C P G Q C ++ + SG C C + C Q C G++G +
Sbjct: 132 SSECAPGMWGPQCDKPCSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPA----- 186
Query: 466 GCR-RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCD--------------------- 503
C+ RCQC+ PCDP +G+C+C TG CD
Sbjct: 187 -CQFRCQCHG-------APCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNG 238
Query: 504 ----------RCLPGHWGL---------SHDLLGCRPCDCDVGGALDPQCDEGTGQCHCR 544
C PG G H + C C GG CD TGQC C
Sbjct: 239 GVFQTPQGSCSCPPGWMGTICSLPCPEGFHGPNCSQECRCHNGGL----CDRFTGQCRCA 294
Query: 545 QHMVGRRCEQVQP 557
G RC + P
Sbjct: 295 PGYTGDRCREECP 307
Score = 57.4 bits (137), Expect = 1e-07
Identities = 74/300 (24%), Positives = 97/300 (32%), Gaps = 78/300 (26%)
Query: 285 CYGHASECAPAPGA---PAHAEGMVHGACICKHNTRGLNC---EQCQD------------ 326
C H + C P GA PA G C T G C CQ+
Sbjct: 191 CQCHGAPCDPQTGACFCPAERTGPSCDVS-CSQGTSGFFCPSTHSCQNGGVFQTPQGSCS 249
Query: 327 ----FYRDLPWRPAEDG-HSHAC-RKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHN 380
+ + P +G H C ++C CH +GG+CD
Sbjct: 250 CPPGWMGTICSLPCPEGFHGPNCSQECRCH-------------------NGGLCD----R 286
Query: 381 TAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRC 440
G+ C C P + D ++ C G CD D +G C C
Sbjct: 287 FTGQ-CR-CAPGYTGDRCRE--------ECPVGRFGQDCAETCDCAPDARCFPANGACLC 336
Query: 441 KEHVVGTRC--QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
+ G RC + C DGF+GLS CQ S C P +G C C
Sbjct: 337 EHGFTGDRCTDRLCPDGFYGLS---------CQAPCTCDREHSLSCHPMNGECSCLPGWA 387
Query: 499 GRGCDRCLPGHWGLSHDLLGCRP-CDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQP 557
G C+ P +H GC+ C C GG C +G C C G C + P
Sbjct: 388 GLHCNESCPQD---THG-PGCQEHCLCLHGGV----CQATSGLCQCAPGYTGPHCASLCP 439
Score = 56.2 bits (134), Expect = 3e-07
Identities = 74/295 (25%), Positives = 100/295 (33%), Gaps = 77/295 (26%)
Query: 282 NCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHS 341
+C C H + C+P GA C C G +C+ LP + G
Sbjct: 493 SCQC-AHEAVCSPQTGA-----------CTCTPGWHGAHCQ--------LPCPKGQFGEG 532
Query: 342 HACRKCECHGHTHSCHFDMAVYLASGNVSGGVCD-GCQHNTAGRHCE------------- 387
A R C+C H+ C G C C G +C
Sbjct: 533 CASR-CDCD-HSDGCDPVHGRCQCQAGWMGARCHLSCPEGLWGVNCSNTCTCKNGGTCLP 590
Query: 388 -----LCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGG-RCDSHD--DPALGLVSGQCR 439
+C P F R P+ RSC G + +C +H P+ +G C
Sbjct: 591 ENGNCVCAPGF--------RGPSCQRSCQPGRYGKRCVPCKCANHSFCHPS----NGTCY 638
Query: 440 CKEHVVGTRCQQ-CRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVT 498
C G C Q C G +G + + + CQC+ GT C P GSC C T
Sbjct: 639 CLAGWTGPDCSQPCPPGHWGENCA-----QTCQCHHGGT------CHPQDGSCICPLGWT 687
Query: 499 GRGC-DRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRC 552
G C + C G +G + +PC C G +C TG C C G C
Sbjct: 688 GHHCLEGCPLGTFGANCS----QPCQCGPG----EKCHPETGACVCPPGHSGAPC 734
Score = 37.7 bits (86), Expect = 0.10
Identities = 17/42 (40%), Positives = 21/42 (50%), Gaps = 4/42 (9%)
Query: 772 LSTLIYNGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRC 813
L T N + PCQC P +C+P G C+C PG G C
Sbjct: 697 LGTFGANCSQPCQCGP----GEKCHPETGACVCPPGHSGAPC 734
>gi|164414431 netrin G1 isoform 1 [Homo sapiens]
Length = 539
Score = 160 bits (406), Expect = 8e-39
Identities = 129/496 (26%), Positives = 217/496 (43%), Gaps = 82/496 (16%)
Query: 46 SCYPATGDLLVGRADRLTASS-TCGLNGPQPYCIVSHLQDEKKCFLCDSRRPFSARDNPH 104
+C P + D+ +L TCG + P+ +C + + ++C++ S + H
Sbjct: 49 ACQPESTDMTKYLKVKLDPPDITCG-DPPETFCAMGNP------YMCNNECDASTPELAH 101
Query: 105 SHRIQNVVTSFAPQRRAAWWQS----ENGIPA-VTIQLDLEAEFHFT-HLIMTFKTFRPA 158
+ + F + + +WQS E P V I L T ++++TF++ RP
Sbjct: 102 PPEL---MFDFEGRHPSTFWQSATWKEYPKPLQVNITLSWSKTIELTDNIVITFESGRPD 158
Query: 159 AMLVERSADFGRTWHVYRYFSYDCGADFPGVPLAPP---RHWD-DVVCESRYSEIEPSTE 214
M++E+S D+GRTW Y+Y++ DC F P + +H +++C YS +
Sbjct: 159 QMILEKSLDYGRTWQPYQYYATDCLDAFHMDPKSVKDLSQHTVLEIICTEEYSTGYTTNS 218
Query: 215 GEVIYRVLDPAIPIPDPY-------------SSRIQNLLKITNLRVNLTRLHTLGDNLLD 261
+ + + D P + ++++ +T+LR+ L R +G+ +D
Sbjct: 219 KIIHFEIKDRFAFFAGPRLRNMASLYGQLDTTKKLRDFFTVTDLRIRLLR-PAVGEIFVD 277
Query: 262 PRREIREKYYYALYELVVRGNCFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNC 321
R Y+YA+ ++ VRG C C HA+ C C C+HNT G +C
Sbjct: 278 ELHLAR--YFYAISDIKVRGRCKCNLHATVCVYDNSKLT---------CECEHNTTGPDC 326
Query: 322 EQCQDFYRDLPWRPAE-----DGHSHAC-------RKCECHGHTHSCHF-DMAVYLASGN 368
+C+ Y+ PW P G ++ C CEC GH++ C + D+
Sbjct: 327 GKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDL-------- 378
Query: 369 VSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAVCRSCDCDPMGSQDGGRCDSHDD 428
++ +C C+HNT G+HCELCR ++R+ + L D VC C C+P+GS RC+
Sbjct: 379 LNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIH-DRCNG--- 434
Query: 429 PALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNS 488
SG C CK G +C +C G S GC+ C+ + N+
Sbjct: 435 ------SGFCECKTGTTGPKCDECLPG-----NSWHYGCQPNVCDNELLHCQNGGTCHNN 483
Query: 489 GSCYCKRLVTGRGCDR 504
C C TG C++
Sbjct: 484 VRCLCPAAYTGILCEK 499
Score = 86.7 bits (213), Expect = 2e-16
Identities = 63/218 (28%), Positives = 87/218 (39%), Gaps = 43/218 (19%)
Query: 940 ATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCE-----CSGNIDP 994
AT C D + ++ C C TG C C + G P PG + + C +I
Sbjct: 303 ATVCVYD--NSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISS 360
Query: 995 MDPDACDPHTGQC-----------LRCLHHTEGPHCAHCKPGFHGQAARQ-----SCHRC 1038
+ C H+ +C + C H+T G HC C+ G+ A+ Q C C
Sbjct: 361 IGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIEC 420
Query: 1039 TCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAP-NFWNLTSGHGCQPCAC 1097
CN LG+ +C SG C C GP CD C P N W+ +GCQP C
Sbjct: 421 YCNPLGSIHDRC---------NGSGFCECKTGTTGPKCDECLPGNSWH----YGCQPNVC 467
Query: 1098 HPSR---ARGPTCNEFTGQCHCRAGFGGRTCSE--CQE 1130
G TC+ +C C A + G C + C+E
Sbjct: 468 DNELLHCQNGGTCHN-NVRCLCPAAYTGILCEKLRCEE 504
Score = 73.2 bits (178), Expect = 2e-12
Identities = 61/229 (26%), Positives = 93/229 (40%), Gaps = 41/229 (17%)
Query: 346 KCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDP-------- 397
+C+C+ H C +D + C+ C+HNT G C C+ + P
Sbjct: 296 RCKCNLHATVCVYDNSKL---------TCE-CEHNTTGPDCGKCKKNYQGRPWSPGSYLP 345
Query: 398 ----TKDLRDPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCR 453
T + P++ +C+ G + RC S+ D ++ CK + G C+ CR
Sbjct: 346 IPKGTANTCIPSISSIGNCECFGHSN--RC-SYIDLLNTVIC--VSCKHNTRGQHCELCR 400
Query: 454 DGFF---GLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPG-- 508
G+F + D C C CN G++ C+ SG C CK TG CD CLPG
Sbjct: 401 LGYFRNASAQLDDENVCIECYCNPLGSIHDR--CN-GSGFCECKTGTTGPKCDECLPGNS 457
Query: 509 -HWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQ 556
H+G ++ C GG C +C C G CE+++
Sbjct: 458 WHYGCQPNVCDNELLHCQNGGT----CHNNV-RCLCPAAYTGILCEKLR 501
Score = 64.3 bits (155), Expect = 1e-09
Identities = 53/216 (24%), Positives = 84/216 (38%), Gaps = 46/216 (21%)
Query: 831 CQCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFP---------------SCR 875
C+C+ + + + + C C G C +C++ G P +C
Sbjct: 297 CKCNLHATVC-VYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCI 355
Query: 876 P-------CVCNGHADECN----THTGACLGCRDHTGGEHCERCIAGF--HGDPRLPYGG 922
P C C GH++ C+ +T C+ C+ +T G+HCE C G+ + +L
Sbjct: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
Query: 923 QCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPG---HFG-DPSR 978
C C C P H D + C C+ G TG +C+ C PG H+G P+
Sbjct: 416 VCIECYC--NPLGSIH-------DRCNGSGFCECKTGTTGPKCDECLPGNSWHYGCQPNV 466
Query: 979 PGGRCQLCE----CSGNIDPMDPDACDPHTGQCLRC 1010
C+ C N+ + P A + LRC
Sbjct: 467 CDNELLHCQNGGTCHNNVRCLCPAAYTGILCEKLRC 502
Score = 62.8 bits (151), Expect = 3e-09
Identities = 52/210 (24%), Positives = 76/210 (36%), Gaps = 43/210 (20%)
Query: 1000 CDPHTGQCL--------RCLHHTEGPHCAHCKPGFHGQAARQSCH----RCTCNLLGTNP 1047
C+ H C+ C H+T GP C CK + G+ + + T N T
Sbjct: 299 CNLHATVCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTAN---TCI 355
Query: 1048 QQCPSPDQCHCDPSSGQCP------------CLPNVQGPSCDRCAPNFWNLTSG-----H 1090
S C C S +C C N +G C+ C ++ S +
Sbjct: 356 PSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDEN 415
Query: 1091 GCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACD-----C 1145
C C C+P + CN +G C C+ G G C EC + G Q + CD C
Sbjct: 416 VCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHC 474
Query: 1146 DSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
+ G CH C C +G+ C++
Sbjct: 475 QNGG----TCHN-NVRCLCPAAYTGILCEK 499
Score = 58.5 bits (140), Expect = 6e-08
Identities = 33/95 (34%), Positives = 45/95 (47%), Gaps = 13/95 (13%)
Query: 778 NGALPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPG---YYGFGPTGC--QACQ 832
N + C CNP GS+ CN G C CK G G +CD C PG +YG P C +
Sbjct: 415 NVCIECYCNPLGSIHDRCN-GSGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLH 473
Query: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCD--RCQ 865
C + G + + +CLC G+ C+ RC+
Sbjct: 474 CQNGGTCHN-----NVRCLCPAAYTGILCEKLRCE 503
Score = 57.4 bits (137), Expect = 1e-07
Identities = 35/118 (29%), Positives = 47/118 (39%), Gaps = 20/118 (16%)
Query: 794 ECNPHGGQCL------------CKPGVVGRRCDLCAPGYYGFGPTG------CQACQCSH 835
EC H +C CK G+ C+LC GY+ C C C+
Sbjct: 365 ECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNP 424
Query: 836 EGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGFPSCRPCVCNGHADECNTHTGAC 893
G++ C SG C C+TG G +CD C G C+P VC+ C + G C
Sbjct: 425 LGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHYGCQPNVCDNELLHCQ-NGGTC 480
Score = 54.7 bits (130), Expect = 8e-07
Identities = 46/180 (25%), Positives = 66/180 (36%), Gaps = 38/180 (21%)
Query: 1037 RCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGCQ--- 1093
RC CNL T C D S C C N GP C +C N+ G
Sbjct: 296 RCKCNLHAT---------VCVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSYLPI 346
Query: 1094 ----PCACHPSRARGPTCNEF--TGQCH------------CRAGFGGRTCSECQELHWGD 1135
C PS + C F + +C C+ G+ C C+ ++ +
Sbjct: 347 PKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGYFRN 406
Query: 1136 PGLQ------CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGFSGIFPACHP 1189
Q C C C+ G +C+ +G C C+ G +G +CD+C G S + C P
Sbjct: 407 ASAQLDDENVCIECYCNPLGSIHDRCNG-SGFCECKTGTTGPKCDECLPGNSWHY-GCQP 464
Score = 47.0 bits (110), Expect = 2e-04
Identities = 33/142 (23%), Positives = 57/142 (40%), Gaps = 22/142 (15%)
Query: 438 CRCKEHVVGTRCQQCRDGFFGLSISDRLGCRRCQCNARGTVP-----GSTPCDPNSGSCY 492
C C+ + G C +C+ + G S + A +P G+ C +S C
Sbjct: 315 CECEHNTTGPDCGKCKKNYQGRPWSPGSYLPIPKGTANTCIPSISSIGNCECFGHSNRCS 374
Query: 493 ------------CKRLVTGRGCDRCLPGHWGLSHDLLG----CRPCDCDVGGALDPQCDE 536
CK G+ C+ C G++ + L C C C+ G++ +C+
Sbjct: 375 YIDLLNTVICVSCKHNTRGQHCELCRLGYFRNASAQLDDENVCIECYCNPLGSIHDRCN- 433
Query: 537 GTGQCHCRQHMVGRRCEQVQPG 558
G+G C C+ G +C++ PG
Sbjct: 434 GSGFCECKTGTTGPKCDECLPG 455
Score = 34.3 bits (77), Expect = 1.1
Identities = 29/122 (23%), Positives = 45/122 (36%), Gaps = 23/122 (18%)
Query: 460 SISDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC 519
+ISD RC+CN TV D + +C C+ TG C +C + G
Sbjct: 287 AISDIKVRGRCKCNLHATV---CVYDNSKLTCECEHNTTGPDCGKCKKNYQGRPWSPGSY 343
Query: 520 RP--------CDCDVGGALDPQCDEGTGQCH------------CRQHMVGRRCEQVQPGY 559
P C + + +C + +C C+ + G+ CE + GY
Sbjct: 344 LPIPKGTANTCIPSISSIGNCECFGHSNRCSYIDLLNTVICVSCKHNTRGQHCELCRLGY 403
Query: 560 FR 561
FR
Sbjct: 404 FR 405
>gi|157419140 laminin, gamma 2 isoform b precursor [Homo sapiens]
Length = 1111
Score = 159 bits (402), Expect = 2e-38
Identities = 89/247 (36%), Positives = 113/247 (45%), Gaps = 36/247 (14%)
Query: 849 QCLCRTGAFGLRCDRCQRGQ-------WGFPSCRPCVCNGHADECNTHTGACLGCRDHTG 901
QC+C G G C C G F +C PC C G C+ TG C D
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
Query: 902 GEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCH-CRAGY 960
C C GF+ DP P C+PCPC H SC ++++VC+ C G
Sbjct: 439 DIECADCPIGFYNDPHDPRS--CKPCPC--------HNGFSCSVMPETEEVVCNNCPPGV 488
Query: 961 TGLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
TG RCE CA G+FGDP G CQ C+C+ N+DP CD TG+CL+C+H+T G
Sbjct: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
Query: 1018 HCAHCKPGFHGQA----ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQG 1073
+C CK G+ G C C CN +G+ P C S G C C P G
Sbjct: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC---------RSDGTCVCKPGFGG 599
Query: 1074 PSCDRCA 1080
P+C+ A
Sbjct: 600 PNCEHGA 606
Score = 122 bits (305), Expect = 4e-27
Identities = 182/761 (23%), Positives = 282/761 (37%), Gaps = 141/761 (18%)
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
C C GY G C+ CA G+ D +R P G C C C G ACDP TG C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYS-- 433
Query: 1012 HHTEGP--HCAHCKPGFHGQAAR-QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCL 1068
E P CA C GF+ +SC C C+ G + P ++ C+ CP
Sbjct: 434 -GDENPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMPETEEVVCN----NCP-- 485
Query: 1069 PNVQGPSCDRCAPNFWNLTSG-HG----CQPCACHPS--RARGPTCNEFTGQC-HCRAGF 1120
P V G C+ CA ++ G HG CQPC C+ + + C+ TG+C C
Sbjct: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 1121 GGRTCSECQELHWGDP-----GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
G C +C+ ++GDP +C AC+C+ G + C R G C C+PG G C+
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Query: 1176 CARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-------QTGVLGAFE 1228
A FS C AC+ + + QR+E + Q T + G +
Sbjct: 605 GA--FS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQ 654
Query: 1229 SSFWHMQE-------------KLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEH 1275
+ +Q+ LG+ V ++ S S ++ T E R +G ++
Sbjct: 655 QAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQN 714
Query: 1276 --------LTQLEADLTDVQDENFNAN-----HALSGLERDRLALNLTLRQLDQHLDLLK 1322
+TQ++ L + + N N H + LA T R + H++
Sbjct: 715 RVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEAT-RLAESHVE--S 771
Query: 1323 HSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSK 1382
SN Q+ R+A + S + A + E L +
Sbjct: 772 ASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLT 831
Query: 1383 HMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSC 1442
A Q + ++ H+L L D S G D+ Q
Sbjct: 832 REATQAEIEADRSYQHSLRLLD----------------SVSRLQGVSDQSFQVEEAKRIK 875
Query: 1443 NGAAATADLA---LGRARHTQ-------AELQRALAEGGSILSRVAETRRQASEAQQRAQ 1492
A + + L + + TQ E Q+ L G S + + +A+ A+ RAQ
Sbjct: 876 QKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQ 935
Query: 1493 AALDKANASRGQVEQANQELQELIQSVKD-------------FLNQEGADPDSIEMVATR 1539
AL NA+ +VE + L+E V + +++Q+ +D A R
Sbjct: 936 EALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAER 995
Query: 1540 VLELSIPASAEQIQHLAG-------AIAERVRSL-----ADVDAILARTVGDVRRAEQLL 1587
L S A A++ ++ AG I + + SL D LA G L
Sbjct: 996 ALG-SAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKG----LASLK 1050
Query: 1588 QDARRARSWAEDEKQKAET----VQAALEEAQRAQGIAQGA 1624
+ R E ++ + +T VQ + EAQ+ A+ A
Sbjct: 1051 SEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNA 1091
Score = 114 bits (284), Expect = 1e-24
Identities = 68/184 (36%), Positives = 89/184 (48%), Gaps = 28/184 (15%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
C+C+G + C FD ++ +GN G C C NT G HCE C+ FYR +D
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR----- 80
Query: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF-----GLSI 461
C C+C+ GS RCD+ SG+C CK V G RC +C GF G +
Sbjct: 81 CLPCNCNSKGSLSA-RCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCR 520
RL +C C+ G + PCD +G C CK VTG CDRC G++ L + GC
Sbjct: 131 DQRLLDSKCDCDPAGI---AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
Query: 521 PCDC 524
C C
Sbjct: 186 QCFC 189
Score = 98.6 bits (244), Expect = 5e-20
Identities = 75/244 (30%), Positives = 96/244 (39%), Gaps = 43/244 (17%)
Query: 801 QCLCKPGVVGRRCDLCAPGY----YGFGPTG-CQACQCSHEGALSSLCEKTSGQCLCRTG 855
QC+C G G+ C CA GY GP G C C C GA C+ +G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 856 AFGLRCDRCQRGQWGFP----SCRPCVC-NGHADEC--NTHTGACLGCRDHTGGEHCERC 908
+ C C G + P SC+PC C NG + T C C G CE C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 909 IAGFHGDPRLPYG--GQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYT 961
G+ GDP +G C+PC C P G+ C C
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRC----------LKCIHNTA 546
Query: 962 GLRCEACAPGHFGDP--SRPGGRCQLCECSGNIDPM--DPDACDPHTGQCLRCLHHTEGP 1017
G+ C+ C G+FGDP P +C+ C C +PM +P C G C+ C GP
Sbjct: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNC----NPMGSEPVGC-RSDGTCV-CKPGFGGP 600
Query: 1018 HCAH 1021
+C H
Sbjct: 601 NCEH 604
Score = 97.4 bits (241), Expect = 1e-19
Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 17/121 (14%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC--------QACQ 832
LPC CN +GSLS+ C+ + G+C CKPGV G RCD C PG++ GC C
Sbjct: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
Query: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADECN 887
C G ++ C+ +G+C+C+ G RCDRC+ G + C C C GH+ C
Sbjct: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCR 197
Query: 888 T 888
+
Sbjct: 198 S 198
Score = 94.4 bits (233), Expect = 9e-19
Identities = 62/201 (30%), Positives = 83/201 (41%), Gaps = 34/201 (16%)
Query: 977 SRPGGRCQLCECSGNIDPMDPDA-CDPHTG---QCLRCLHHTEGPHCAHCKPGFHGQAAR 1032
+R R ++C+C+G D TG +CL C +T+G HC CK GF+ R
Sbjct: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
Query: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092
C C CN G+ +C +SG+C C P V G CDRC P F LT GC
Sbjct: 79 DRCLPCNCNSKGSLSARC---------DNSGRCSCKPGVTGARCDRCLPGFHMLTDA-GC 128
Query: 1093 --------QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACD 1144
C C P+ GP C+ G+C C+ G C C+ ++ G C
Sbjct: 129 TQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGC- 184
Query: 1145 CDSRGIDTPQCHRFTGHCSCR 1165
QC + SCR
Sbjct: 185 --------TQCFCYGHSASCR 197
Score = 93.2 bits (230), Expect = 2e-18
Identities = 58/160 (36%), Positives = 80/160 (50%), Gaps = 22/160 (13%)
Query: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
CDC+ Q + H G +C C ++ G C++C++GF+ DR C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGF---RCLNCNDNTDGIHCEKCKNGFYRHRERDR--CL 82
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC--------R 520
C CN++G++ S CD NSG C CK VTG CDRCLPG L+ GC
Sbjct: 83 PCNCNSKGSL--SARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
Query: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
CDCD G P CD G+C C+ + G RC++ + GY+
Sbjct: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
Score = 85.5 bits (210), Expect = 4e-16
Identities = 75/273 (27%), Positives = 97/273 (35%), Gaps = 52/273 (19%)
Query: 294 PAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHT 353
P GAPA CIC +G C+ C Y+ A G C C C G
Sbjct: 370 PVSGAPAPWVEQ----CICPVGYKGQFCQDCASGYKR---DSARLGPFGTCIPCNCQG-- 420
Query: 354 HSCHFDMAVYLASGNVSGGVCD----GCQHNTAGR--HCELCRPFFYRDPTKDLRDPAVC 407
GG CD C C C FY DP DP C
Sbjct: 421 -----------------GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSC 459
Query: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR--- 464
+ C C +G C + + + C V G RC+ C DG+FG +
Sbjct: 460 KPCPC-----HNGFSCSVMPETEEVVCN---NCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWG---LSHDLLGCR 520
C+ CQCN S CD +G C C G CD+C G++G + CR
Sbjct: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCR 571
Query: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
C+C+ G+ +P G C C+ G CE
Sbjct: 572 ACNCNPMGS-EPVGCRSDGTCVCKPGFGGPNCE 603
Score = 84.3 bits (207), Expect = 9e-16
Identities = 54/145 (37%), Positives = 73/145 (50%), Gaps = 22/145 (15%)
Query: 782 PCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG--FGPTG----CQACQCS 834
PC C+ S S C C PGV G RC+LCA GY+G FG G CQ CQC+
Sbjct: 461 PCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN 520
Query: 835 H--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP-------SCRPCVCNGHAD 884
+ + + S C++ +G+CL C G+ CD+C+ G +G P CR C CN
Sbjct: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
Query: 885 E---CNTHTGACLGCRDHTGGEHCE 906
E C + G C+ C+ GG +CE
Sbjct: 581 EPVGCRS-DGTCV-CKPGFGGPNCE 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 56/180 (31%), Positives = 77/180 (42%), Gaps = 20/180 (11%)
Query: 1030 AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSG-QC-PCLPNVQGPSCDRCAPNFWNLT 1087
AAR + R C+ G + +QC + H +G +C C N G C++C F+
Sbjct: 18 AARATSRREVCDCNGKS-RQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
Query: 1088 SGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQE-LHW-------GDPGLQ 1139
C PC C+ + C+ +G+C C+ G G C C H D L
Sbjct: 77 ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF----SGIFPACHPCHACFG 1195
CDCD GI P C G C C+P V+G RCD+C G+ G C C C+G
Sbjct: 136 DSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCF-CYG 191
Score = 77.4 bits (189), Expect = 1e-13
Identities = 60/206 (29%), Positives = 80/206 (38%), Gaps = 54/206 (26%)
Query: 877 CVCNGHADEC------NTHTG---ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPC 927
C CNG + +C + TG CL C D+T G HCE+C GF+ R +C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY---RHRERDRCLPC 84
Query: 928 PCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF--------GDPSRP 979
C S+ + C C C+ G TG RC+ C PG D
Sbjct: 85 NC----NSKGSLSARCDNSGR-----CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039
+C C+ +G P D G+C+ C G C C+ G++
Sbjct: 136 DSKCD-CDPAGIAGPCD-------AGRCV-CKPAVTGERCDRCRSGYY------------ 174
Query: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQC 1065
NL G NP+ C QC C S C
Sbjct: 175 -NLDGGNPEGC---TQCFCYGHSASC 196
Score = 74.3 bits (181), Expect = 1e-12
Identities = 61/212 (28%), Positives = 83/212 (39%), Gaps = 35/212 (16%)
Query: 1002 PHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQ----SCHRCTCNLLGTNPQQCPSPDQCH 1057
P QC+ C +G C C G+ +AR +C C C G
Sbjct: 377 PWVEQCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA------------ 423
Query: 1058 CDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSG-HGCQPCACHP--SRARGPTCNEFTGQC 1114
CDP +G C C C F+N C+PC CH S + P E
Sbjct: 424 CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCN- 482
Query: 1115 HCRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGID---TPQCHRFTGHC-SC 1164
+C G G C C + ++GDP + C C C++ +D + C R TG C C
Sbjct: 483 NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKC 541
Query: 1165 RPGVSGVRCDQCARGFSGIFPACHP---CHAC 1193
+G+ CDQC G+ G A +P C AC
Sbjct: 542 IHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC 573
Score = 70.5 bits (171), Expect = 1e-11
Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 33/171 (19%)
Query: 783 CQCNPQGSLSSEC---------NPHGGQCL-CKPGVVGRRCDLCAPGYYGFGPTG-CQAC 831
C CN + S +C +G +CL C G C+ C G+Y C C
Sbjct: 28 CDCNGK---SRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPC 84
Query: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRG------------QWGFPSCRPCVC 879
C+ +G+LS+ C+ SG+C C+ G G RCDRC G Q S C
Sbjct: 85 NCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 880 NGHADECNTHTGACLGCRDHTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
G A C+ G C+ C+ GE C+RC +G++ D P G C C C
Sbjct: 144 AGIAGPCD--AGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEG--CTQCFC 189
Score = 66.2 bits (160), Expect = 3e-10
Identities = 58/223 (26%), Positives = 84/223 (37%), Gaps = 28/223 (12%)
Query: 350 HGHTHSCHFDMAVYLASGNVSGGVCDG-----CQHNTAGRHCELCRPFFYRDPTKDLRDP 404
+G + + D +++ VSG C G+ C+ C + RD + L
Sbjct: 352 YGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSAR-LGPF 410
Query: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR 464
C C+C Q GG CD +G C + C C GF+ D
Sbjct: 411 GTCIPCNC-----QGGGACDPD--------TGDCYSGDENPDIECADCPIGFYN-DPHDP 456
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG----CR 520
C+ C C+ G P C VTG C+ C G++G G C+
Sbjct: 457 RSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
Query: 521 PCDCD--VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
PC C+ V + CD TG+C C + G C+Q + GYF
Sbjct: 516 PCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 14/136 (10%)
Query: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQCNARGTVPGSTPCDPNSGSCY 492
QC C G CQ C G+ S RLG C C C G CDP++G CY
Sbjct: 381 QCICPVGYKGQFCQDCASGY--KRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
Query: 493 CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRR 551
C C G + HD C+PC C G + + C +C + G R
Sbjct: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 552 CEQVQPGYF-RPFLDH 566
CE GYF PF +H
Sbjct: 493 CELCADGYFGDPFGEH 508
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 19/105 (18%)
Query: 1094 PCACHPSRARGPTCNEFTGQC-----------------HCRAGFGGRTCSECQELHWGDP 1136
P A SR CN + QC +C G C +C+ +
Sbjct: 17 PAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
Query: 1137 GL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180
+C C+C+S+G + +C +G CSC+PGV+G RCD+C GF
Sbjct: 77 ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120
Score = 43.5 bits (101), Expect = 0.002
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356
G C+CK G C++C+ Y +L + G+ C +C C+GH+ SC
Sbjct: 153 GRCVCKPAVTGERCDRCRSGYYNL-----DGGNPEGCTQCFCYGHSASC 196
Score = 41.2 bits (95), Expect = 0.009
Identities = 66/296 (22%), Positives = 122/296 (41%), Gaps = 42/296 (14%)
Query: 1510 QELQELIQSVKDFLNQEGADPDSIEMVATRVLELSIPASAEQIQHLAGAI--------AE 1561
Q L E ++ K Q + E+ A R + S+ + + L G A+
Sbjct: 814 QGLVEKLEKTKSLAQQLTREATQAEIEADRSYQHSLRL-LDSVSRLQGVSDQSFQVEEAK 872
Query: 1562 RVRSLAD-VDAILARTVGDVRR-----------AEQLLQDARRARSWAEDEKQKAETVQA 1609
R++ AD + +++ R + + +R A+QLLQ+ + R E Q
Sbjct: 873 RIKQKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGR---EKSDQLLSRANL 929
Query: 1610 ALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQL-DALLE 1668
A AQ A + + ++ + QV R A AE A+ ++++ DA +
Sbjct: 930 AKSRAQEALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDK 989
Query: 1669 ALKLKRAGNSLAAST--AEETAGSAQGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLA 1726
+ +RA S AA A+ AG A + E EQ + ++ A A G LA
Sbjct: 990 TQQAERALGSAAADAQRAKNGAGEALEISSEIEQ--------EIGSLNLEANVTADGALA 1041
Query: 1727 AQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALESKAAQLDGLEARMRS 1782
+ L+ E R++ + +L+R +ELE ++ N A++ + ++ R ++
Sbjct: 1042 MEKGLASLKSEMREV----EGELER-KELE--FDTNMDAVQMVITEAQKVDTRAKN 1090
Score = 36.2 bits (82), Expect = 0.30
Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 10/72 (13%)
Query: 286 YGHASECAPA-------PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
+G C P P A + + + C HNT G+ C+QC+ Y P P
Sbjct: 508 HGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP--- 564
Query: 339 GHSHACRKCECH 350
+ CR C C+
Sbjct: 565 NPADKCRACNCN 576
>gi|157419138 laminin, gamma 2 isoform a precursor [Homo sapiens]
Length = 1193
Score = 159 bits (402), Expect = 2e-38
Identities = 89/247 (36%), Positives = 113/247 (45%), Gaps = 36/247 (14%)
Query: 849 QCLCRTGAFGLRCDRCQRGQ-------WGFPSCRPCVCNGHADECNTHTGACLGCRDHTG 901
QC+C G G C C G F +C PC C G C+ TG C D
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQG-GGACDPDTGDCYS-GDENP 438
Query: 902 GEHCERCIAGFHGDPRLPYGGQCRPCPCPEGPGSQRHFATSCHQDEYSQQIVCH-CRAGY 960
C C GF+ DP P C+PCPC H SC ++++VC+ C G
Sbjct: 439 DIECADCPIGFYNDPHDPRS--CKPCPC--------HNGFSCSVMPETEEVVCNNCPPGV 488
Query: 961 TGLRCEACAPGHFGDPSRPGGR---CQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGP 1017
TG RCE CA G+FGDP G CQ C+C+ N+DP CD TG+CL+C+H+T G
Sbjct: 489 TGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGI 548
Query: 1018 HCAHCKPGFHGQA----ARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQG 1073
+C CK G+ G C C CN +G+ P C S G C C P G
Sbjct: 549 YCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC---------RSDGTCVCKPGFGG 599
Query: 1074 PSCDRCA 1080
P+C+ A
Sbjct: 600 PNCEHGA 606
Score = 125 bits (313), Expect = 5e-28
Identities = 208/877 (23%), Positives = 326/877 (37%), Gaps = 162/877 (18%)
Query: 954 CHCRAGYTGLRCEACAPGHFGDPSR--PGGRCQLCECSGNIDPMDPDACDPHTGQCLRCL 1011
C C GY G C+ CA G+ D +R P G C C C G ACDP TG C
Sbjct: 382 CICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGG------GACDPDTGDCYS-- 433
Query: 1012 HHTEGP--HCAHCKPGFHGQAAR-QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCL 1068
E P CA C GF+ +SC C C+ G + P ++ C+ CP
Sbjct: 434 -GDENPDIECADCPIGFYNDPHDPRSCKPCPCHN-GFSCSVMPETEEVVCN----NCP-- 485
Query: 1069 PNVQGPSCDRCAPNFWNLTSG-HG----CQPCACHPS--RARGPTCNEFTGQC-HCRAGF 1120
P V G C+ CA ++ G HG CQPC C+ + + C+ TG+C C
Sbjct: 486 PGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNT 545
Query: 1121 GGRTCSECQELHWGDP-----GLQCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQ 1175
G C +C+ ++GDP +C AC+C+ G + C R G C C+PG G C+
Sbjct: 546 AGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGSEPVGC-RSDGTCVCKPGFGGPNCEH 604
Query: 1176 CARGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQ-------QTGVLGAFE 1228
A FS C AC+ + + QR+E + Q T + G +
Sbjct: 605 GA--FS--------CPACYNQVKIQMDQFMQQLQRMEALISKAQGGDGVVPDTELEGRMQ 654
Query: 1229 SSFWHMQE-------------KLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEH 1275
+ +Q+ LG+ V ++ S S ++ T E R +G ++
Sbjct: 655 QAEQALQDILRDAQISEGASRSLGLQLAKVRSQENSYQSRLDDLKMTVERVRALGSQYQN 714
Query: 1276 --------LTQLEADLTDVQDENFNAN-----HALSGLERDRLALNLTLRQLDQHLDLLK 1322
+TQ++ L + + N N H + LA T R + H++
Sbjct: 715 RVRDTHRLITQMQLSLAESEASLGNTNIPASDHYVGPNGFKSLAQEAT-RLAESHVE--S 771
Query: 1323 HSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSPVSNSASARHRTEALMDAQKEDFNSK 1382
SN Q+ R+A + S + A + E L +
Sbjct: 772 ASNMEQLTRETEDYSKQALSLVRKALHEGVGSGSGSPDGAVVQGLVEKLEKTKSLAQQLT 831
Query: 1383 HMANQRALGKLSAHTHTLSLTDINELVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSC 1442
A Q + ++ H+L L D S G D+ Q
Sbjct: 832 REATQAEIEADRSYQHSLRLLD----------------SVSRLQGVSDQSFQVEEAKRIK 875
Query: 1443 NGAAATADLA---LGRARHTQ-------AELQRALAEGGSILSRVAETRRQASEAQQRAQ 1492
A + + L + + TQ E Q+ L G S + + +A+ A+ RAQ
Sbjct: 876 QKADSLSSLVTRHMDEFKRTQKNLGNWKEEAQQLLQNGKSGREKSDQLLSRANLAKSRAQ 935
Query: 1493 AALDKANASRGQVEQANQELQELIQSVKD-------------FLNQEGADPDSIEMVATR 1539
AL NA+ +VE + L+E V + +++Q+ +D A R
Sbjct: 936 EALSMGNATFYEVESILKNLREFDLQVDNRKAEAEEAMKRLSYISQKVSDASDKTQQAER 995
Query: 1540 VLELSIPASAEQIQHLAG-------AIAERVRSL-----ADVDAILARTVGDVRRAEQLL 1587
L S A A++ ++ AG I + + SL D LA G L
Sbjct: 996 ALG-SAAADAQRAKNGAGEALEISSEIEQEIGSLNLEANVTADGALAMEKG----LASLK 1050
Query: 1588 QDARRARSWAEDEKQKAET----VQAALEEAQRAQGIAQGAIRGAVADTRDT-EQTLYQV 1642
+ R E ++ + +T VQ + EAQ+ A+ A + DT +T + L+ +
Sbjct: 1051 SEMREVEGELERKELEFDTNMDAVQMVITEAQKVDTRAKNA-GVTIQDTLNTLDGLLHLM 1109
Query: 1643 QERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAA------STAEETAGSAQGRAQ 1696
+ ++ E L LLE KL RA + + S EE A +G
Sbjct: 1110 DQPLSVDEEGL-----------VLLEQ-KLSRAKTQINSQLRPMMSELEERARQQRGHLH 1157
Query: 1697 EAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQ 1733
E + G L D + ++ + + G QA +Q
Sbjct: 1158 LLETSIDGILAD-VKNLENIRDNLPPGCYNTQALEQQ 1193
Score = 114 bits (284), Expect = 1e-24
Identities = 68/184 (36%), Positives = 89/184 (48%), Gaps = 28/184 (15%)
Query: 347 CECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLRDPAV 406
C+C+G + C FD ++ +GN G C C NT G HCE C+ FYR +D
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGN--GFRCLNCNDNTDGIHCEKCKNGFYRHRERDR----- 80
Query: 407 CRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFF-----GLSI 461
C C+C+ GS RCD+ SG+C CK V G RC +C GF G +
Sbjct: 81 CLPCNCNSKGSLSA-RCDN---------SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQ 130
Query: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGL-SHDLLGCR 520
RL +C C+ G + PCD +G C CK VTG CDRC G++ L + GC
Sbjct: 131 DQRLLDSKCDCDPAGI---AGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCT 185
Query: 521 PCDC 524
C C
Sbjct: 186 QCFC 189
Score = 98.6 bits (244), Expect = 5e-20
Identities = 75/244 (30%), Positives = 96/244 (39%), Gaps = 43/244 (17%)
Query: 801 QCLCKPGVVGRRCDLCAPGY----YGFGPTG-CQACQCSHEGALSSLCEKTSGQCLCRTG 855
QC+C G G+ C CA GY GP G C C C GA C+ +G C
Sbjct: 381 QCICPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA----CDPDTGDCYSGDE 436
Query: 856 AFGLRCDRCQRGQWGFP----SCRPCVC-NGHADEC--NTHTGACLGCRDHTGGEHCERC 908
+ C C G + P SC+PC C NG + T C C G CE C
Sbjct: 437 NPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELC 496
Query: 909 IAGFHGDPRLPYG--GQCRPCPC-----PEGPGSQRHFATSCHQDEYSQQIVCHCRAGYT 961
G+ GDP +G C+PC C P G+ C C
Sbjct: 497 ADGYFGDPFGEHGPVRPCQPCQCNNNVDPSASGNCDRLTGRC----------LKCIHNTA 546
Query: 962 GLRCEACAPGHFGDP--SRPGGRCQLCECSGNIDPM--DPDACDPHTGQCLRCLHHTEGP 1017
G+ C+ C G+FGDP P +C+ C C +PM +P C G C+ C GP
Sbjct: 547 GIYCDQCKAGYFGDPLAPNPADKCRACNC----NPMGSEPVGC-RSDGTCV-CKPGFGGP 600
Query: 1018 HCAH 1021
+C H
Sbjct: 601 NCEH 604
Score = 97.4 bits (241), Expect = 1e-19
Identities = 46/121 (38%), Positives = 64/121 (52%), Gaps = 17/121 (14%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCLCKPGVVGRRCDLCAPGYYGFGPTGC--------QACQ 832
LPC CN +GSLS+ C+ + G+C CKPGV G RCD C PG++ GC C
Sbjct: 82 LPCNCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCD 140
Query: 833 CSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRGQWGF-----PSCRPCVCNGHADECN 887
C G ++ C+ +G+C+C+ G RCDRC+ G + C C C GH+ C
Sbjct: 141 CDPAG-IAGPCD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCFCYGHSASCR 197
Query: 888 T 888
+
Sbjct: 198 S 198
Score = 94.4 bits (233), Expect = 9e-19
Identities = 62/201 (30%), Positives = 83/201 (41%), Gaps = 34/201 (16%)
Query: 977 SRPGGRCQLCECSGNIDPMDPDA-CDPHTG---QCLRCLHHTEGPHCAHCKPGFHGQAAR 1032
+R R ++C+C+G D TG +CL C +T+G HC CK GF+ R
Sbjct: 19 ARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRER 78
Query: 1033 QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSGHGC 1092
C C CN G+ +C +SG+C C P V G CDRC P F LT GC
Sbjct: 79 DRCLPCNCNSKGSLSARC---------DNSGRCSCKPGVTGARCDRCLPGFHMLTDA-GC 128
Query: 1093 --------QPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQELHWGDPGLQCHACD 1144
C C P+ GP C+ G+C C+ G C C+ ++ G C
Sbjct: 129 TQDQRLLDSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGC- 184
Query: 1145 CDSRGIDTPQCHRFTGHCSCR 1165
QC + SCR
Sbjct: 185 --------TQCFCYGHSASCR 197
Score = 93.2 bits (230), Expect = 2e-18
Identities = 58/160 (36%), Positives = 80/160 (50%), Gaps = 22/160 (13%)
Query: 410 CDCDPMGSQDGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISDRLGCR 468
CDC+ Q + H G +C C ++ G C++C++GF+ DR C
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGF---RCLNCNDNTDGIHCEKCKNGFYRHRERDR--CL 82
Query: 469 RCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLGC--------R 520
C CN++G++ S CD NSG C CK VTG CDRCLPG L+ GC
Sbjct: 83 PCNCNSKGSL--SARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTD--AGCTQDQRLLDS 137
Query: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCEQVQPGYF 560
CDCD G P CD G+C C+ + G RC++ + GY+
Sbjct: 138 KCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYY 174
Score = 85.5 bits (210), Expect = 4e-16
Identities = 75/273 (27%), Positives = 97/273 (35%), Gaps = 52/273 (19%)
Query: 294 PAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHT 353
P GAPA CIC +G C+ C Y+ A G C C C G
Sbjct: 370 PVSGAPAPWVEQ----CICPVGYKGQFCQDCASGYKR---DSARLGPFGTCIPCNCQG-- 420
Query: 354 HSCHFDMAVYLASGNVSGGVCD----GCQHNTAGR--HCELCRPFFYRDPTKDLRDPAVC 407
GG CD C C C FY DP DP C
Sbjct: 421 -----------------GGACDPDTGDCYSGDENPDIECADCPIGFYNDP----HDPRSC 459
Query: 408 RSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR--- 464
+ C C +G C + + + C V G RC+ C DG+FG +
Sbjct: 460 KPCPC-----HNGFSCSVMPETEEVVCN---NCPPGVTGARCELCADGYFGDPFGEHGPV 511
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCY-CKRLVTGRGCDRCLPGHWG---LSHDLLGCR 520
C+ CQCN S CD +G C C G CD+C G++G + CR
Sbjct: 512 RPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCR 571
Query: 521 PCDCDVGGALDPQCDEGTGQCHCRQHMVGRRCE 553
C+C+ G+ +P G C C+ G CE
Sbjct: 572 ACNCNPMGS-EPVGCRSDGTCVCKPGFGGPNCE 603
Score = 84.3 bits (207), Expect = 9e-16
Identities = 54/145 (37%), Positives = 73/145 (50%), Gaps = 22/145 (15%)
Query: 782 PCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG--FGPTG----CQACQCS 834
PC C+ S S C C PGV G RC+LCA GY+G FG G CQ CQC+
Sbjct: 461 PCPCHNGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCN 520
Query: 835 H--EGALSSLCEKTSGQCL-CRTGAFGLRCDRCQRGQWGFP-------SCRPCVCNGHAD 884
+ + + S C++ +G+CL C G+ CD+C+ G +G P CR C CN
Sbjct: 521 NNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAPNPADKCRACNCNPMGS 580
Query: 885 E---CNTHTGACLGCRDHTGGEHCE 906
E C + G C+ C+ GG +CE
Sbjct: 581 EPVGCRS-DGTCV-CKPGFGGPNCE 603
Score = 80.5 bits (197), Expect = 1e-14
Identities = 56/180 (31%), Positives = 77/180 (42%), Gaps = 20/180 (11%)
Query: 1030 AARQSCHRCTCNLLGTNPQQCPSPDQCHCDPSSG-QC-PCLPNVQGPSCDRCAPNFWNLT 1087
AAR + R C+ G + +QC + H +G +C C N G C++C F+
Sbjct: 18 AARATSRREVCDCNGKS-RQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
Query: 1088 SGHGCQPCACHPSRARGPTCNEFTGQCHCRAGFGGRTCSECQE-LHW-------GDPGLQ 1139
C PC C+ + C+ +G+C C+ G G C C H D L
Sbjct: 77 ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 1140 CHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF----SGIFPACHPCHACFG 1195
CDCD GI P C G C C+P V+G RCD+C G+ G C C C+G
Sbjct: 136 DSKCDCDPAGIAGP-CD--AGRCVCKPAVTGERCDRCRSGYYNLDGGNPEGCTQCF-CYG 191
Score = 77.4 bits (189), Expect = 1e-13
Identities = 60/206 (29%), Positives = 80/206 (38%), Gaps = 54/206 (26%)
Query: 877 CVCNGHADEC------NTHTG---ACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPC 927
C CNG + +C + TG CL C D+T G HCE+C GF+ R +C PC
Sbjct: 28 CDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFY---RHRERDRCLPC 84
Query: 928 PCPEGPGSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHF--------GDPSRP 979
C S+ + C C C+ G TG RC+ C PG D
Sbjct: 85 NC----NSKGSLSARCDNSGR-----CSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLL 135
Query: 980 GGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQSCHRCT 1039
+C C+ +G P D G+C+ C G C C+ G++
Sbjct: 136 DSKCD-CDPAGIAGPCD-------AGRCV-CKPAVTGERCDRCRSGYY------------ 174
Query: 1040 CNLLGTNPQQCPSPDQCHCDPSSGQC 1065
NL G NP+ C QC C S C
Sbjct: 175 -NLDGGNPEGC---TQCFCYGHSASC 196
Score = 74.3 bits (181), Expect = 1e-12
Identities = 61/212 (28%), Positives = 83/212 (39%), Gaps = 35/212 (16%)
Query: 1002 PHTGQCLRCLHHTEGPHCAHCKPGFHGQAARQ----SCHRCTCNLLGTNPQQCPSPDQCH 1057
P QC+ C +G C C G+ +AR +C C C G
Sbjct: 377 PWVEQCI-CPVGYKGQFCQDCASGYKRDSARLGPFGTCIPCNCQGGGA------------ 423
Query: 1058 CDPSSGQCPCLPNVQGPSCDRCAPNFWNLTSG-HGCQPCACHP--SRARGPTCNEFTGQC 1114
CDP +G C C C F+N C+PC CH S + P E
Sbjct: 424 CDPDTGDCYSGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCN- 482
Query: 1115 HCRAGFGGRTCSECQELHWGDPGLQ------CHACDCDSRGID---TPQCHRFTGHC-SC 1164
+C G G C C + ++GDP + C C C++ +D + C R TG C C
Sbjct: 483 NCPPGVTGARCELCADGYFGDPFGEHGPVRPCQPCQCNNN-VDPSASGNCDRLTGRCLKC 541
Query: 1165 RPGVSGVRCDQCARGFSGIFPACHP---CHAC 1193
+G+ CDQC G+ G A +P C AC
Sbjct: 542 IHNTAGIYCDQCKAGYFGDPLAPNPADKCRAC 573
Score = 70.5 bits (171), Expect = 1e-11
Identities = 54/171 (31%), Positives = 74/171 (43%), Gaps = 33/171 (19%)
Query: 783 CQCNPQGSLSSEC---------NPHGGQCL-CKPGVVGRRCDLCAPGYYGFGPTG-CQAC 831
C CN + S +C +G +CL C G C+ C G+Y C C
Sbjct: 28 CDCNGK---SRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHRERDRCLPC 84
Query: 832 QCSHEGALSSLCEKTSGQCLCRTGAFGLRCDRCQRG------------QWGFPSCRPCVC 879
C+ +G+LS+ C+ SG+C C+ G G RCDRC G Q S C
Sbjct: 85 NCNSKGSLSARCD-NSGRCSCKPGVTGARCDRCLPGFHMLTDAGCTQDQRLLDSKCDCDP 143
Query: 880 NGHADECNTHTGACLGCRDHTGGEHCERCIAGFHG-DPRLPYGGQCRPCPC 929
G A C+ G C+ C+ GE C+RC +G++ D P G C C C
Sbjct: 144 AGIAGPCD--AGRCV-CKPAVTGERCDRCRSGYYNLDGGNPEG--CTQCFC 189
Score = 66.2 bits (160), Expect = 3e-10
Identities = 58/223 (26%), Positives = 84/223 (37%), Gaps = 28/223 (12%)
Query: 350 HGHTHSCHFDMAVYLASGNVSGGVCDG-----CQHNTAGRHCELCRPFFYRDPTKDLRDP 404
+G + + D +++ VSG C G+ C+ C + RD + L
Sbjct: 352 YGEYSTGYIDNVTLISARPVSGAPAPWVEQCICPVGYKGQFCQDCASGYKRDSAR-LGPF 410
Query: 405 AVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGLSISDR 464
C C+C Q GG CD +G C + C C GF+ D
Sbjct: 411 GTCIPCNC-----QGGGACDPD--------TGDCYSGDENPDIECADCPIGFYN-DPHDP 456
Query: 465 LGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDLLG----CR 520
C+ C C+ G P C VTG C+ C G++G G C+
Sbjct: 457 RSCKPCPCH-NGFSCSVMPETEEVVCNNCPPGVTGARCELCADGYFGDPFGEHGPVRPCQ 515
Query: 521 PCDCD--VGGALDPQCDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
PC C+ V + CD TG+C C + G C+Q + GYF
Sbjct: 516 PCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYF 558
Score = 63.2 bits (152), Expect = 2e-09
Identities = 44/136 (32%), Positives = 54/136 (39%), Gaps = 14/136 (10%)
Query: 437 QCRCKEHVVGTRCQQCRDGFFGLSISDRLG----CRRCQCNARGTVPGSTPCDPNSGSCY 492
QC C G CQ C G+ S RLG C C C G CDP++G CY
Sbjct: 381 QCICPVGYKGQFCQDCASGY--KRDSARLGPFGTCIPCNCQGGGA------CDPDTGDCY 432
Query: 493 CKRLVTGRGCDRCLPGHWGLSHDLLGCRPCDCDVGGALDPQCDEGTGQC-HCRQHMVGRR 551
C C G + HD C+PC C G + + C +C + G R
Sbjct: 433 SGDENPDIECADCPIGFYNDPHDPRSCKPCPCHNGFSCSVMPETEEVVCNNCPPGVTGAR 492
Query: 552 CEQVQPGYF-RPFLDH 566
CE GYF PF +H
Sbjct: 493 CELCADGYFGDPFGEH 508
Score = 53.1 bits (126), Expect = 2e-06
Identities = 32/105 (30%), Positives = 47/105 (44%), Gaps = 19/105 (18%)
Query: 1094 PCACHPSRARGPTCNEFTGQC-----------------HCRAGFGGRTCSECQELHWGDP 1136
P A SR CN + QC +C G C +C+ +
Sbjct: 17 PAARATSRREVCDCNGKSRQCIFDRELHRQTGNGFRCLNCNDNTDGIHCEKCKNGFYRHR 76
Query: 1137 GL-QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCARGF 1180
+C C+C+S+G + +C +G CSC+PGV+G RCD+C GF
Sbjct: 77 ERDRCLPCNCNSKGSLSARCDN-SGRCSCKPGVTGARCDRCLPGF 120
Score = 43.5 bits (101), Expect = 0.002
Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 5/49 (10%)
Query: 308 GACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSHACRKCECHGHTHSC 356
G C+CK G C++C+ Y +L + G+ C +C C+GH+ SC
Sbjct: 153 GRCVCKPAVTGERCDRCRSGYYNL-----DGGNPEGCTQCFCYGHSASC 196
Score = 36.2 bits (82), Expect = 0.30
Identities = 20/72 (27%), Positives = 29/72 (40%), Gaps = 10/72 (13%)
Query: 286 YGHASECAPA-------PGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAED 338
+G C P P A + + + C HNT G+ C+QC+ Y P P
Sbjct: 508 HGPVRPCQPCQCNNNVDPSASGNCDRLTGRCLKCIHNTAGIYCDQCKAGYFGDPLAP--- 564
Query: 339 GHSHACRKCECH 350
+ CR C C+
Sbjct: 565 NPADKCRACNCN 576
>gi|157419124 laminin, alpha 4 isoform 1 precursor [Homo sapiens]
Length = 1823
Score = 159 bits (402), Expect = 2e-38
Identities = 85/223 (38%), Positives = 118/223 (52%), Gaps = 29/223 (13%)
Query: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
C PC CNG+++EC +G C+ C+ +T GEHCE+C+ G+ GD C+PCPCP
Sbjct: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136
Query: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
+FA SC++ + + C C Y G CE CAPG++G+P G C+ C+CSGN D
Sbjct: 137 PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194
Query: 994 P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051
P + + CD TGQC CL +T G C C PG++G A ++C C C G P
Sbjct: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247
Query: 1052 SPDQCHCDPSSGQC-------PCLPNVQGPSCDRCAPNFWNLT 1087
CD +G+C P + SCD+C W+LT
Sbjct: 248 ------CDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDLT 281
Score = 110 bits (275), Expect = 1e-23
Identities = 188/844 (22%), Positives = 313/844 (37%), Gaps = 138/844 (16%)
Query: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
E C G F S G C C+C+GN + C +G C+ C +T G HC C G
Sbjct: 65 EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
+ G + R Q C C C L P + C+ + +C C N GP+C+RCAP
Sbjct: 117 YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
Query: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136
++ L G C+ C C + C+E TGQC +C G C C ++GD
Sbjct: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
Query: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHC---SCRPGVS----GVRCDQCA---------- 1177
+ C C+C C TG C P + CD+C
Sbjct: 233 RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGMDCPTISCDKCVWDLTDALRLA 287
Query: 1178 -----RGFSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SS 1230
G SG+ A R V ++ A L+ + E + L + ++
Sbjct: 288 ALSIEEGKSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNA 342
Query: 1231 FWHMQEKLGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDEN 1290
M+ L V+ +V N A+ QLV+ +E + H +QL D++D+
Sbjct: 343 ENTMKSLLSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKI 395
Query: 1291 FNANHALSGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTS 1350
N+ + + L+ +++ + L L + L S + +Q + A+
Sbjct: 396 QEINNKMLYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-E 449
Query: 1351 ALAVPSPVSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINE 1407
A + S + + T L Q +D+N+K Q AL + A + D+N
Sbjct: 450 AYELLSQAESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNR 507
Query: 1408 LVCGAPGDAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRAL 1467
D + + R N + +T+ +L R T +EL +
Sbjct: 508 ATAARQRDH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDII 555
Query: 1468 AEGGSILSRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-E 1526
I AE SE Q + + +N S V++A Q+L Q + +
Sbjct: 556 KNASGI---YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLH 609
Query: 1527 GADPDSI---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRA 1583
+D + + + A+ V E + +E + A+ R V I + + +
Sbjct: 610 SSDMNGLVQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDES 669
Query: 1584 EQLLQDARRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQG 1623
E LL AR ++ AE +A + A+++ Q A+ G AQ
Sbjct: 670 ENLLNQARELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQ 729
Query: 1624 AIRGAVADTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAAST 1683
+ + T + +T +VQ+ A L++ + + D S A +T
Sbjct: 730 RLGQSRLITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNT 776
Query: 1684 AEETAGSA-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLL 1742
A +A A + + QLL DQ +TV+ +R A V A+ R +L + R +
Sbjct: 777 AVNSARDAVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVA 829
Query: 1743 QAAQ 1746
Q
Sbjct: 830 SKIQ 833
Score = 103 bits (258), Expect = 1e-21
Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833
+PC CN S+EC G C+ C+ G C+ C GY G P CQ C C
Sbjct: 80 VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
Query: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884
H + C + +G +C+C G C+RC G +G P +C+ C C+G++D
Sbjct: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196
Query: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
+C+ TG C C +T G CERC G++GD R+ C C C GP
Sbjct: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247
Score = 97.4 bits (241), Expect = 1e-19
Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%)
Query: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
S C C+C+G+++ C G+ G C CQ NT G HCE C + D +
Sbjct: 76 SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459
P C+ C C P + C + +C C E+ G C++C G++G
Sbjct: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176
Query: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516
+ C++C C+ P CD +G C C R TG C+RC PG++G +
Sbjct: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541
C C+C G CD TG+C
Sbjct: 236 KNCAVCNCGGG-----PCDSVTGEC 255
Score = 89.7 bits (221), Expect = 2e-17
Identities = 72/242 (29%), Positives = 100/242 (41%), Gaps = 47/242 (19%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C G+++EC G H C+ NT G +CE+C D Y R G
Sbjct: 82 CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
C+ C C H +F + Y +G V C C N AG +CE C P +Y +P L
Sbjct: 128 FCQPCPC-PLPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461
+ C+ CDC G+ D D V+GQCR C + G +C++C G++G
Sbjct: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYG-DA 232
Query: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRG-------CDRCLPGHWGLSH 514
C C C G PCD +G C + G CD+C+ W L+
Sbjct: 233 RIAKNCAVCNC-------GGGPCDSVTGECLEEGFEPPTGMDCPTISCDKCV---WDLTD 282
Query: 515 DL 516
L
Sbjct: 283 AL 284
Score = 83.6 bits (205), Expect = 2e-15
Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%)
Query: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463
C CDC+ ++ DG SG C C+ + G C++C DG+ G SI
Sbjct: 79 CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518
C+ C C + C +G+ C C G C+RC PG++G + L+G
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183
Query: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
C+ CDC G DP CDE TGQC +C ++ G +CE+ PGY+
Sbjct: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 73.2 bits (178), Expect = 2e-12
Identities = 46/148 (31%), Positives = 67/148 (45%), Gaps = 23/148 (15%)
Query: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835
PC + + C G +C+C G C+ CAPGYYG G T C+ C CS
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191
Query: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887
+ + C++ +GQC C G +C+RC G +G +C C C G C+
Sbjct: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249
Query: 888 THTGACL--GCRDHTGGE----HCERCI 909
+ TG CL G TG + C++C+
Sbjct: 250 SVTGECLEEGFEPPTGMDCPTISCDKCV 277
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%)
Query: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508
++C GFF + C C CN S C SG C +C+R TG C++CL G
Sbjct: 65 EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560
+ G S + G C+PC C + + C G +C C ++ G CE+ PGY+
Sbjct: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Score = 56.2 bits (134), Expect = 3e-07
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132
P+ ++C F++ SG C PC C+ C + +G C HC+ G C +C + +
Sbjct: 62 PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182
GD C C C + C+R G C C +G C++CA G+ G
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 1183 --IFPACHPCHACFGDWD 1198
I C C C G+ D
Sbjct: 178 LLIGSTCKKCD-CSGNSD 194
Score = 39.3 bits (90), Expect = 0.035
Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%)
Query: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527
S+LS V E + ++A ++ Q ++D N + VEQA+ ++++ IQ + + + G
Sbjct: 348 SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 406
Query: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587
+ ELS +E++ LA + E +RS R + D A++
Sbjct: 407 EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 451
Query: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647
+ +A SW + LE+ A D ++ L Q +
Sbjct: 452 ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 500
Query: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707
AE + R R + E ++ + +++ ST+ ++ + + E + +++ G
Sbjct: 501 DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 560
Query: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767
+ A +E Q + L + + DL+Q A D Q LQ+ E NE + +
Sbjct: 561 IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 607
Query: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795
++ ++GL ++ L A N+ I N
Sbjct: 608 LHSSDMNGL---VQKALDASNVYENIVN 632
>gi|157419126 laminin, alpha 4 isoform 2 precursor [Homo sapiens]
Length = 1816
Score = 159 bits (401), Expect = 3e-38
Identities = 83/216 (38%), Positives = 115/216 (53%), Gaps = 22/216 (10%)
Query: 874 CRPCVCNGHADECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
C PC CNG+++EC +G C+ C+ +T GEHCE+C+ G+ GD C+PCPCP
Sbjct: 79 CVPCDCNGNSNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCP--L 136
Query: 934 GSQRHFATSCHQDEYSQQIVCHCRAGYTGLRCEACAPGHFGDPSRPGGRCQLCECSGNID 993
+FA SC++ + + C C Y G CE CAPG++G+P G C+ C+CSGN D
Sbjct: 137 PHLANFAESCYRK--NGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSD 194
Query: 994 P-MDPDACDPHTGQCLRCLHHTEGPHCAHCKPGFHGQA-ARQSCHRCTCNLLGTNPQQCP 1051
P + + CD TGQC CL +T G C C PG++G A ++C C C G P
Sbjct: 195 PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNC---GGGP---- 247
Query: 1052 SPDQCHCDPSSGQCPCLPNVQGPSCDRCAPNFWNLT 1087
CD +G+C CD+C W+LT
Sbjct: 248 ------CDSVTGECLEEGFEPPTGCDKCV---WDLT 274
Score = 113 bits (283), Expect = 1e-24
Identities = 187/837 (22%), Positives = 311/837 (37%), Gaps = 131/837 (15%)
Query: 966 EACAPGHFGDPSRPGGRCQLCECSGNIDPMDPDACDPHTGQCLRCLHHTEGPHCAHCKPG 1025
E C G F S G C C+C+GN + C +G C+ C +T G HC C G
Sbjct: 65 EKCNAGFFHTLS---GECVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 1026 FHGQAAR---QSCHRCTCNLLGTNPQQCPSPDQCHCDPSSGQCPCLPNVQGPSCDRCAPN 1082
+ G + R Q C C C L P + C+ + +C C N GP+C+RCAP
Sbjct: 117 YIGDSIRGAPQFCQPCPCPL----PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPG 172
Query: 1083 FWN--LTSGHGCQPCACHPSRARG---PTCNEFTGQC-HCRAGFGGRTCSECQELHWGDP 1136
++ L G C+ C C + C+E TGQC +C G C C ++GD
Sbjct: 173 YYGNPLLIGSTCKKCDCSGNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDA 232
Query: 1137 GL--QCHACDCDSRGIDTPQCHRFTGHCSCRPGVSGVRCDQCA---------------RG 1179
+ C C+C C TG C CD+C G
Sbjct: 233 RIAKNCAVCNCGG-----GPCDSVTGECLEEGFEPPTGCDKCVWDLTDALRLAALSIEEG 287
Query: 1180 FSGIFPACHPCHACFGDWDRVVQDLAARTQRLEQRAQELQQTGVLGAFE--SSFWHMQEK 1237
SG+ A R V ++ A L+ + E + L + ++ M+
Sbjct: 288 KSGVLSVSSGAAA-----HRHVNEINATIYLLKTKLSERENQYALRKIQINNAENTMKSL 342
Query: 1238 LGIVQGIVGARNTSAASTAQLVEATEELRREIGEATEHLTQLEADLTDVQDENFNANHAL 1297
L V+ +V N A+ QLV+ +E + H +QL D++D+ N+ +
Sbjct: 343 LSDVEELVEKEN-QASRKGQLVQ------KESMDTINHASQLVEQAHDMRDKIQEINNKM 395
Query: 1298 SGLERDRLALNLTLRQLDQHLDLLKHSNFLGAYDSIRHAHSQSAEAERRANTSALAVPSP 1357
+ L+ +++ + L L + L S + +Q + A+ A + S
Sbjct: 396 LYYGEEH---ELSPKEISEKLVLAQ--KMLEEIRSRQPFFTQRELVDEEAD-EAYELLSQ 449
Query: 1358 VSNSASARHRTEALMDA---QKEDFNSKHMANQRALGKLSAHTHTLSLTDINELVCGAPG 1414
+ + T L Q +D+N+K Q AL + A + D+N
Sbjct: 450 AESWQRLHNETRTLFPVVLEQLDDYNAKLSDLQEALDQ--ALNYVRDAEDMNRATAARQR 507
Query: 1415 DAPCATSPCGGAGCRDEDGQPRCGGLSCNGAAATADLALGRARHTQAELQRALAEGGSIL 1474
D + + R N + +T+ +L R T +EL + I
Sbjct: 508 DH------------EKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASGI- 554
Query: 1475 SRVAETRRQASEAQQRAQAALDKANASRGQVEQANQELQELIQSVKDFLNQ-EGADPDSI 1533
AE SE Q + + +N S V++A Q+L Q + + +D + +
Sbjct: 555 --YAEIDGAKSELQVKLS---NLSNLSHDLVQEAIDHAQDLQQEANELSRKLHSSDMNGL 609
Query: 1534 ---EMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLLQDA 1590
+ A+ V E + +E + A+ R V I + + +E LL A
Sbjct: 610 VQKALDASNVYENIVNYVSEANETAEFALNTTDRIYDAVSGIDTQIIYHKDESENLLNQA 669
Query: 1591 RRARSWAEDEKQKA-------------------ETVQAALEEAQRAQ-GIAQGAIRGAVA 1630
R ++ AE +A + A+++ Q A+ G AQ + +
Sbjct: 670 RELQAKAESSSDEAVADTSRRVGGALARKSALKTRLSDAVKQLQAAERGDAQQRLGQSRL 729
Query: 1631 DTRDTEQTLYQVQERMAGAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGS 1690
T + +T +VQ+ A L++ + + D S A +TA +A
Sbjct: 730 ITEEANRTTMEVQQATAPMANNLTNWSQNLQHFD-------------SSAYNTAVNSARD 776
Query: 1691 A-QGRAQEAEQLLRGPLGDQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQ 1746
A + + QLL DQ +TV+ +R A V A+ R +L + R + Q
Sbjct: 777 AVRNLTEVVPQLL-----DQLRTVE--QKRPASNVSASIQRIRELIAQTRSVASKIQ 826
Score = 103 bits (258), Expect = 1e-21
Identities = 58/173 (33%), Positives = 81/173 (46%), Gaps = 25/173 (14%)
Query: 781 LPCQCNPQGSLSSECNPHGGQCL-CKPGVVGRRCDLCAPGYYG----FGPTGCQACQC-- 833
+PC CN S+EC G C+ C+ G C+ C GY G P CQ C C
Sbjct: 80 VPCDCNGN---SNECLDGSGYCVHCQRNTTGEHCEKCLDGYIGDSIRGAPQFCQPCPCPL 136
Query: 834 SHEGALSSLCEKTSG--QCLCRTGAFGLRCDRCQRGQWGFP-----SCRPCVCNGHAD-- 884
H + C + +G +C+C G C+RC G +G P +C+ C C+G++D
Sbjct: 137 PHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGSTCKKCDCSGNSDPN 196
Query: 885 ----ECNTHTGACLGCRDHTGGEHCERCIAGFHGDPRLPYGGQCRPCPCPEGP 933
+C+ TG C C +T G CERC G++GD R+ C C C GP
Sbjct: 197 LIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARI--AKNCAVCNCGGGP 247
Score = 97.4 bits (241), Expect = 1e-19
Identities = 60/205 (29%), Positives = 88/205 (42%), Gaps = 29/205 (14%)
Query: 341 SHACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKD 400
S C C+C+G+++ C G+ G C CQ NT G HCE C + D +
Sbjct: 76 SGECVPCDCNGNSNEC--------LDGS---GYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 401 LRDPAVCRSCDCD-PMGSQDGGRCDSHDDPALGLVSGQCRCKEHVVGTRCQQCRDGFFGL 459
P C+ C C P + C + +C C E+ G C++C G++G
Sbjct: 125 A--PQFCQPCPCPLPHLANFAESCYRKNGAV------RCICNENYAGPNCERCAPGYYGN 176
Query: 460 SISDRLGCRRCQCNARGTVPG--STPCDPNSGSC-YCKRLVTGRGCDRCLPGHWGLSHDL 516
+ C++C C+ P CD +G C C R TG C+RC PG++G +
Sbjct: 177 PLLIGSTCKKCDCSGNSD-PNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIA 235
Query: 517 LGCRPCDCDVGGALDPQCDEGTGQC 541
C C+C G CD TG+C
Sbjct: 236 KNCAVCNCGGG-----PCDSVTGEC 255
Score = 96.7 bits (239), Expect = 2e-19
Identities = 72/235 (30%), Positives = 102/235 (43%), Gaps = 40/235 (17%)
Query: 283 CFCYGHASECAPAPGAPAHAEGMVHGACICKHNTRGLNCEQCQDFYRDLPWRPAEDGHSH 342
C C G+++EC G H C+ NT G +CE+C D Y R G
Sbjct: 82 CDCNGNSNECLDGSGYCVH----------CQRNTTGEHCEKCLDGYIGDSIR----GAPQ 127
Query: 343 ACRKCECHGHTHSCHFDMAVYLASGNVSGGVCDGCQHNTAGRHCELCRPFFYRDPTKDLR 402
C+ C C H +F + Y +G V C C N AG +CE C P +Y +P L
Sbjct: 128 FCQPCPCP-LPHLANFAESCYRKNGAVR---CI-CNENYAGPNCERCAPGYYGNP---LL 179
Query: 403 DPAVCRSCDCDPMGSQDGGRCDSHDDPALGLVSGQCR-CKEHVVGTRCQQCRDGFFGLSI 461
+ C+ CDC G+ D D V+GQCR C + G +C++C G++G +
Sbjct: 180 IGSTCKKCDCS--GNSDPNLIFEDCDE----VTGQCRNCLRNTTGFKCERCAPGYYGDAR 233
Query: 462 SDRLGCRRCQCNARGTVPGSTPCDPNSGSCYCKRLVTGRGCDRCLPGHWGLSHDL 516
+ C C C G PCD +G C + GCD+C+ W L+ L
Sbjct: 234 IAK-NCAVCNC-------GGGPCDSVTGECLEEGFEPPTGCDKCV---WDLTDAL 277
Score = 83.6 bits (205), Expect = 2e-15
Identities = 55/168 (32%), Positives = 79/168 (47%), Gaps = 31/168 (18%)
Query: 407 CRSCDCDPMGSQ--DGGRCDSHDDPALGLVSGQC-RCKEHVVGTRCQQCRDGFFGLSISD 463
C CDC+ ++ DG SG C C+ + G C++C DG+ G SI
Sbjct: 79 CVPCDCNGNSNECLDG--------------SGYCVHCQRNTTGEHCEKCLDGYIGDSIRG 124
Query: 464 RLG-CRRCQCNARGTVPGSTPCDPNSGS--CYCKRLVTGRGCDRCLPGHWGLSHDLLG-- 518
C+ C C + C +G+ C C G C+RC PG++G + L+G
Sbjct: 125 APQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYG-NPLLIGST 183
Query: 519 CRPCDCDVGGALDPQ-----CDEGTGQC-HCRQHMVGRRCEQVQPGYF 560
C+ CDC G DP CDE TGQC +C ++ G +CE+ PGY+
Sbjct: 184 CKKCDCS--GNSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYY 229
Score = 74.3 bits (181), Expect = 1e-12
Identities = 46/144 (31%), Positives = 66/144 (45%), Gaps = 22/144 (15%)
Query: 782 PCQCNPQGSLSSECNPHGG--QCLCKPGVVGRRCDLCAPGYYG----FGPTGCQACQCSH 835
PC + + C G +C+C G C+ CAPGYYG G T C+ C CS
Sbjct: 133 PCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNPLLIGST-CKKCDCSG 191
Query: 836 EGALSSL---CEKTSGQCL-CRTGAFGLRCDRCQRGQWG----FPSCRPCVCNGHADECN 887
+ + C++ +GQC C G +C+RC G +G +C C C G C+
Sbjct: 192 NSDPNLIFEDCDEVTGQCRNCLRNTTGFKCERCAPGYYGDARIAKNCAVCNCGG--GPCD 249
Query: 888 THTGACL--GCRDHTGGEHCERCI 909
+ TG CL G TG C++C+
Sbjct: 250 SVTGECLEEGFEPPTG---CDKCV 270
Score = 58.9 bits (141), Expect = 4e-08
Identities = 38/120 (31%), Positives = 55/120 (45%), Gaps = 19/120 (15%)
Query: 450 QQCRDGFFGLSISDRLGCRRCQCNARGTVPGSTPCDPNSGSC-YCKRLVTGRGCDRCLPG 508
++C GFF + C C CN S C SG C +C+R TG C++CL G
Sbjct: 65 EKCNAGFFHTLSGE---CVPCDCNGN-----SNECLDGSGYCVHCQRNTTGEHCEKCLDG 116
Query: 509 HWGLSHDLLG----CRPCDCDVGGALD--PQC--DEGTGQCHCRQHMVGRRCEQVQPGYF 560
+ G S + G C+PC C + + C G +C C ++ G CE+ PGY+
Sbjct: 117 YIGDS--IRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYY 174
Score = 56.2 bits (134), Expect = 3e-07
Identities = 39/138 (28%), Positives = 58/138 (42%), Gaps = 18/138 (13%)
Query: 1074 PSCDRCAPNFWNLTSGHGCQPCACHPSRARGPTCNEFTGQC-HCRAGFGGRTCSECQELH 1132
P+ ++C F++ SG C PC C+ C + +G C HC+ G C +C + +
Sbjct: 62 PAAEKCNAGFFHTLSGE-CVPCDCN---GNSNECLDGSGYCVHCQRNTTGEHCEKCLDGY 117
Query: 1133 WGDP----GLQCHACDCDSRGIDT--PQCHRFTG--HCSCRPGVSGVRCDQCARGFSG-- 1182
GD C C C + C+R G C C +G C++CA G+ G
Sbjct: 118 IGDSIRGAPQFCQPCPCPLPHLANFAESCYRKNGAVRCICNENYAGPNCERCAPGYYGNP 177
Query: 1183 --IFPACHPCHACFGDWD 1198
I C C C G+ D
Sbjct: 178 LLIGSTCKKCD-CSGNSD 194
Score = 39.3 bits (90), Expect = 0.035
Identities = 68/328 (20%), Positives = 134/328 (40%), Gaps = 47/328 (14%)
Query: 1472 SILSRVAETRRQASEAQQRAQA----ALDKANASRGQVEQANQELQELIQSVKDFLNQEG 1527
S+LS V E + ++A ++ Q ++D N + VEQA+ ++++ IQ + + + G
Sbjct: 341 SLLSDVEELVEKENQASRKGQLVQKESMDTINHASQLVEQAH-DMRDKIQEINNKMLYYG 399
Query: 1528 ADPDSIEMVATRVLELSIPASAEQIQHLAGAIAERVRSLADVDAILARTVGDVRRAEQLL 1587
+ ELS +E++ LA + E +RS R + D A++
Sbjct: 400 EEH-----------ELSPKEISEKLV-LAQKMLEEIRSRQPF--FTQRELVD-EEADEAY 444
Query: 1588 QDARRARSWAEDEKQKAETVQAALEEAQRAQGIAQGAIRGAVADTRDTEQTLYQVQERMA 1647
+ +A SW + LE+ A D ++ L Q +
Sbjct: 445 ELLSQAESWQRLHNETRTLFPVVLEQLDDYN-----------AKLSDLQEALDQALNYVR 493
Query: 1648 GAERALSSAGERARQLDALLEALKLKRAGNSLAASTAEETAGSAQGRAQEAEQLLRGPLG 1707
AE + R R + E ++ + +++ ST+ ++ + + E + +++ G
Sbjct: 494 DAEDMNRATAARQRDHEKQQERVREQMEVVNMSLSTSADSLTTPRLTLSELDDIIKNASG 553
Query: 1708 DQYQTVKALAERKAQGVLAAQARAEQLRDEARDLLQAAQDKLQRLQELEGTYEENERALE 1767
+ A +E Q + L + + DL+Q A D Q LQ+ E NE + +
Sbjct: 554 IYAEIDGAKSE--------LQVKLSNLSNLSHDLVQEAIDHAQDLQQ-----EANELSRK 600
Query: 1768 SKAAQLDGLEARMRSVLQAINLQVQIYN 1795
++ ++GL ++ L A N+ I N
Sbjct: 601 LHSSDMNGL---VQKALDASNVYENIVN 625
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.136 0.441
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 80,097,017
Number of Sequences: 37866
Number of extensions: 4433787
Number of successful extensions: 26584
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 753
Number of HSP's that attempted gapping in prelim test: 15239
Number of HSP's gapped (non-prelim): 5341
length of query: 1798
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1681
effective length of database: 13,817,196
effective search space: 23226706476
effective search space used: 23226706476
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.