Search of human proteins with 119395754

Search of human proteins with 119395754

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119395754 keratin 5 [Homo sapiens]
         (590 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119395754 keratin 5 [Homo sapiens]                                1159   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  863   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                862   0.0  
gi|155969697 keratin 6C [Homo sapiens]                                862   0.0  
gi|153791158 keratin 75 [Homo sapiens]                                810   0.0  
gi|109148552 keratin 3 [Homo sapiens]                                 724   0.0  
gi|153791670 keratin 76 [Homo sapiens]                                685   0.0  
gi|119395750 keratin 1 [Homo sapiens]                                 684   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 654   0.0  
gi|47132620 keratin 2 [Homo sapiens]                                  647   0.0  
gi|194018511 keratin 77 [Homo sapiens]                                616   e-176
gi|32567786 keratin 6L [Homo sapiens]                                 610   e-174
gi|28173564 keratin 73 [Homo sapiens]                                 582   e-166
gi|148612803 keratin 6 irs4 [Homo sapiens]                            568   e-162
gi|15618995 keratin 71 [Homo sapiens]                                 566   e-161
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       547   e-156
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      547   e-156
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    539   e-153
gi|67782365 keratin 7 [Homo sapiens]                                  526   e-149
gi|4504919 keratin 8 [Homo sapiens]                                   526   e-149
gi|89357932 keratin 5b [Homo sapiens]                                 493   e-139
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      468   e-132
gi|27477127 keratin 82 [Homo sapiens]                                 453   e-127
gi|4504935 keratin 85 [Homo sapiens]                                  452   e-127
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   437   e-122
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   436   e-122
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   436   e-122
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   436   e-122
gi|14318422 keratin 86 [Homo sapiens]                                 436   e-122
gi|169790841 keratin 83 [Homo sapiens]                                428   e-120

>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score = 1159 bits (2999), Expect = 0.0
 Identities = 590/590 (100%), Positives = 590/590 (100%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60
           MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY
Sbjct: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60

Query: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120
           GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG
Sbjct: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120

Query: 121 AGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFA 180
           AGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFA
Sbjct: 121 AGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFA 180

Query: 181 SFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRL 240
           SFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRL
Sbjct: 181 SFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRL 240

Query: 241 DSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEI 300
           DSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEI
Sbjct: 241 DSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEI 300

Query: 301 NFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESW 360
           NFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESW
Sbjct: 301 NFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESW 360

Query: 361 YQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQR 420
           YQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQR
Sbjct: 361 YQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQR 420

Query: 421 GELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECR 480
           GELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECR
Sbjct: 421 GELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECR 480

Query: 481 LSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGV 540
           LSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGV
Sbjct: 481 LSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGV 540

Query: 541 GLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKS 590
           GLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKS
Sbjct: 541 GLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFKS 590


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  863 bits (2231), Expect = 0.0
 Identities = 454/588 (77%), Positives = 489/588 (83%), Gaps = 27/588 (4%)

Query: 2   SRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           S  +++   S   R FS  SA  P VSR+ F+SVS S   G GG G     GACG  G+G
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLG-----GACGGAGFG 57

Query: 62  SRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
           SRSLY LGGSKRISI     +    +G+ AGG YGFGG AGSGFGFGGGAG GFGLGGGA
Sbjct: 58  SRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGG-AGSGFGFGGGAGIGFGLGGGA 116

Query: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
           G  GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP+IQRVR EEREQIKTLNNKFAS
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFAS 176

Query: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
           FIDKVRFLEQQNKVL+TKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD
Sbjct: 177 FIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236

Query: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
           SELR MQDLVEDFKNKYEDEINKRT AENEFV LKKDVDAAYMNKVEL+AK D L DEIN
Sbjct: 237 SELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
           F++  +DAELSQMQTH+SDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIA RSR EAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
           QTKYEELQ TAGRHGDDLRNTK EI+E+NRMIQRLR+EID+VKKQCANLQ AIADAEQRG
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416

Query: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
           E+ALKDA+NKL  LE+ALQKAKQD+ARLL+EYQELMN KLALDVEIATYRKLLEGEECRL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541
           +GEGVG VNISVV S+VSSGYG  SG G GL          GL GGSS SY         
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGL----------GLGGGSSYSY--------- 517

Query: 542 LGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589
            G GL VGG GFS+SSGR +G G  S GG SS++K+ +T+SSSRKS+K
Sbjct: 518 -GSGLGVGG-GFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYK 563


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  862 bits (2227), Expect = 0.0
 Identities = 453/588 (77%), Positives = 488/588 (82%), Gaps = 27/588 (4%)

Query: 2   SRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           S  +++   S   R FS  SA  P VSR+ F+S+S S   G GG G     GACG  G+G
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLG-----GACGGAGFG 57

Query: 62  SRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
           SRSLY LGGSKRISI     +    +G+ AGG YGFGG AGSGFGFGGGAG GFGLGGGA
Sbjct: 58  SRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGG-AGSGFGFGGGAGIGFGLGGGA 116

Query: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
           G  GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP+IQRVR EEREQIKTLNNKFAS
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176

Query: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
           FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLD+IVGERGRLD
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLD 236

Query: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
           SELRNMQDLVED KNKYEDEINKRT AENEFV LKKDVDAAYMNKVEL+AK D L DEIN
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
           F++  +DAELSQMQTH+SDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIA RSR EAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
           QTKYEELQ TAGRHGDDLRNTK EI+E+NRMIQRLR+EID+VKKQCANLQ AIADAEQRG
Sbjct: 357 QTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRG 416

Query: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
           E+ALKDA+NKL  LE+ALQKAKQD+ARLL+EYQELMN KLALDVEIATYRKLLEGEECRL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541
           +GEGVG VNISVV S+VSSGYG  SG G GL          GL GGSS SY         
Sbjct: 477 NGEGVGQVNISVVQSTVSSGYGGASGVGSGL----------GLGGGSSYSY--------- 517

Query: 542 LGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589
            G GL VGG GFS+SSGR  G G  S GG SS++K+ +T+SSSRKS+K
Sbjct: 518 -GSGLGVGG-GFSSSSGRATGGGLSSVGGGSSTIKYTTTSSSSRKSYK 563


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  862 bits (2226), Expect = 0.0
 Identities = 450/588 (76%), Positives = 489/588 (83%), Gaps = 27/588 (4%)

Query: 2   SRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           S  +++   S   R FS  SA  P VSR+ F+S+S S   G GG G     GACG  G+G
Sbjct: 3   STSTTIRSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLG-----GACGGAGFG 57

Query: 62  SRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
           SRSLY LGGSKRISI     +    +G+ AGG YGFGG AGSGFGFGGGAG GFGLGGGA
Sbjct: 58  SRSLYGLGGSKRISIGGGSCAISGGYGSRAGGSYGFGG-AGSGFGFGGGAGIGFGLGGGA 116

Query: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
           G  GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDP+IQRVR EEREQIKTLNNKFAS
Sbjct: 117 GLAGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFAS 176

Query: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
           FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD
Sbjct: 177 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 236

Query: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
           SELRNMQDLVED KNKYEDEINKRT AENEFV LKKDVDAAYMNKVEL+AK D L DEIN
Sbjct: 237 SELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEIN 296

Query: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
           F++  +DAELSQMQTH+SDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIA RSR EAESWY
Sbjct: 297 FLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWY 356

Query: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
           QTKYEELQ TAGRHGDDLRNTK EI+E+NRMIQRLR+EID+VKKQCA+LQ AIADAEQRG
Sbjct: 357 QTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRG 416

Query: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
           E+ALKDA+NKL  LE+ALQKAKQD+ARLL+EYQELMN KLALDVEIATYRKLLEGEECRL
Sbjct: 417 EMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRL 476

Query: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541
           +GEGVG VN+SVV S++SSGYG  SG G GL          GL GGSS SY         
Sbjct: 477 NGEGVGQVNVSVVQSTISSGYGGASGVGSGL----------GLGGGSSYSY--------- 517

Query: 542 LGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589
            G GL +GG GFS+SSGR +G G  S GG SS++K+ +T+SSSRKS+K
Sbjct: 518 -GSGLGIGG-GFSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKSYK 563


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  810 bits (2093), Expect = 0.0
 Identities = 438/589 (74%), Positives = 481/589 (81%), Gaps = 41/589 (6%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRS-GGGGGGGFGRVSLAGACGVGG 59
           MSRQSS++F+SG  R FST SAITP+  R+ F+SVS +    G GG GR+S AGA     
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSGGLGRISSAGA----S 56

Query: 60  YGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119
           +GSRSLYNLGG+KR+SI+  G S R+ FG  A   +G      SGFG+GGG GGGF    
Sbjct: 57  FGSRSLYNLGGAKRVSINGCGSSCRSGFGGRASNRFG----VNSGFGYGGGVGGGFS--- 109

Query: 120 GAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179
                    GP FPVCPPGGIQEVTVNQSLLTPL+LQIDP+IQRVR EEREQIKTLNNKF
Sbjct: 110 ---------GPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAEEREQIKTLNNKF 160

Query: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239
           ASFIDKVRFLEQQNKVL+TKW LLQEQG++TVRQNLEPLF+ Y + LRRQL+SI  ERGR
Sbjct: 161 ASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELRRQLESITTERGR 220

Query: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299
           L++ELRNMQD+VEDFK +YEDEINKRT AENEFV LKKDVDAAYMNKVELEAKV +L +E
Sbjct: 221 LEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKVELEAKVKSLPEE 280

Query: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359
           INF+   FDAELSQ+QT V DTSVVLSMDNNRNLDLDSIIAEVKAQYE+IANRSR EAES
Sbjct: 281 INFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYEDIANRSRAEAES 340

Query: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419
           WYQTKYEELQ TAGRHGDDLRNTK EISEMNRMIQRLRAEID+VKKQC++LQ AIADAEQ
Sbjct: 341 WYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQCSSLQTAIADAEQ 400

Query: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479
           RGELALKDAR KL +LEEALQKAKQDMARLLREYQELMN KLALDVEIATYRKLLEGEEC
Sbjct: 401 RGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEIATYRKLLEGEEC 460

Query: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539
           RLSGEGV PVNISVVTS++SSGYGSGS  GGG   GLGGG G          Y  ++SGG
Sbjct: 461 RLSGEGVSPVNISVVTSTLSSGYGSGSSIGGG-NLGLGGGSG----------YSFTTSGG 509

Query: 540 VGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSF 588
             LG GL  GGSGFSA+S RGL       GGS SSVKFVSTTSSS+KS+
Sbjct: 510 HSLGAGL--GGSGFSATSNRGL-------GGSGSSVKFVSTTSSSQKSY 549


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  724 bits (1870), Expect = 0.0
 Identities = 406/636 (63%), Positives = 468/636 (73%), Gaps = 61/636 (9%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60
           MSRQ+S +   GGS+ FS  SA+    SR S   V+ SGG GGG +G  S     G GG+
Sbjct: 1   MSRQASKT-SGGGSQGFSGRSAVVSGSSRMS--CVAHSGGAGGGAYGFRS-----GAGGF 52

Query: 61  GSRSLYNLGGSKRISISTS----------------------GGSFRNRFGAGAGGGYGFG 98
           GSRSLYNLGG+K ISIS +                      GG F + +G G GGG+G G
Sbjct: 53  GSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGG 112

Query: 99  GGAGSGFGFGGGAGGGFGLGGGAGFGG--------GFGGPGFPVCP--------PGGIQE 142
            G G GFG  GG GG  G GG  GFGG        GFGGPG    P        PGGIQE
Sbjct: 113 RGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGIQE 172

Query: 143 VTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTL 202
           VT+NQSLL PLN++IDP I +V+ +EREQIKTLNNKFASFIDKVRFLEQQNKVL+TKW L
Sbjct: 173 VTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNL 232

Query: 203 LQEQGTKTVR--QNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYED 260
           LQ+QGT ++    NLEPLFE +IN LR  LD+I+GERGRLDSEL+NM+DLVEDFK KYED
Sbjct: 233 LQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYED 292

Query: 261 EINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSD 320
           EINKRT AENEFV LKKDVD+AYMNKVEL+AKVDAL+DEI+F++  +DAELSQMQ+H+SD
Sbjct: 293 EINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISD 352

Query: 321 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLR 380
           TSVVLSMDNNR+LDLDSIIAEV+AQYE+IA RS+ EAE+ YQTK  ELQ TAGRHGDDLR
Sbjct: 353 TSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLR 412

Query: 381 NTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQ 440
           NTK EI E+NRMIQRLRAEI+ VKKQ ANLQ AIA+AEQ GE+ALKDA  KL EL+ ALQ
Sbjct: 413 NTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQ 472

Query: 441 KAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSS 500
           +AK D+ARLLR+YQELMN KLALDVEIATYRKLLEGEE R+SGE    V+ISVV+SS +S
Sbjct: 473 QAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTS 532

Query: 501 GYGSGSGYGGGLGGGLGGGLGGGL-AGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGR 559
              S  GYGGG GGG+GGGLGGG  AGG SGS +    GG G+GGG   G SGFS  SG 
Sbjct: 533 --ASAGGYGGGYGGGMGGGLGGGFSAGGGSGSGFGRGGGG-GIGGGFGGGSSGFSGGSGF 589

Query: 560 G--LGVGFG-SGGGSSS------SVKFVSTTSSSRK 586
           G   G  +G SGGG SS      S+KF  ++ SS++
Sbjct: 590 GSISGARYGVSGGGFSSASNRGGSIKFSQSSQSSQR 625


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  685 bits (1767), Expect = 0.0
 Identities = 397/642 (61%), Positives = 453/642 (70%), Gaps = 62/642 (9%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60
           M+RQ      SG S+ FS  SA+    SR S   V+RSGG GGG  G  S     G G +
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVVSGSSRMS--CVARSGGAGGGACGFRS-----GAGSF 53

Query: 61  GSRSLYNLGGSKRISISTSGGSFR------NRFGAGAGGGYG--FGGGAGSGFGFGGGAG 112
           GSRSLYNLG +K ISIS + GS R       R   G  GGYG  FGG  G GFG G G G
Sbjct: 54  GSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVG 113

Query: 113 GGFGLGGGAGFGGGFGGPGFPVCP--------------PGGIQEVTVNQSLLTPLNLQID 158
            GFG  GG G  GGFGGPG    P              PGGIQEV VNQSLL PLN++ID
Sbjct: 114 SGFGGAGGFGGAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEID 173

Query: 159 PSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPL 218
           P I +V+ +EREQIKTLNNKFASFIDKVRFLEQQNKVL+TKW LLQ+Q T +   +LEP 
Sbjct: 174 PQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPC 233

Query: 219 FEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKD 278
           FE YI+ L +QLDS++GERG L+ EL++MQDLVEDFK KYEDEINKRT AENEFV LKKD
Sbjct: 234 FESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKD 293

Query: 279 VDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSI 338
           VDAA+MNKVEL+AKVD+L DE++F++  ++ ELSQMQ+H SDTSVVLSMDNNR LDL SI
Sbjct: 294 VDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSI 353

Query: 339 IAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRA 398
           IAEV+AQYEEIA RS++EAE+ YQTK  ELQ TAGRHGDDLRNTK EI E+NRMIQRLRA
Sbjct: 354 IAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRA 413

Query: 399 EIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMN 458
           EI+NVKKQ ANLQ AIA+AEQRGE+ALKDA  KL +L+ ALQKAK D+ARLLR+YQELMN
Sbjct: 414 EIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMN 473

Query: 459 TKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVS---------------SGYG 503
            KLALDVEIATYRKLLEGEECR+SGE    V ISVV++  S               SG G
Sbjct: 474 VKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSG 533

Query: 504 SG-----------SGYG--GGLGGGLGGGLGGGLAG-GSSGSYYSSSSGG-VGLGGGLSV 548
           SG           SGYG  GG G G GG   G   G GSSGSY SSSSG  +G  G +SV
Sbjct: 534 SGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGRGSSGSYQSSSSGSRLGGAGSISV 593

Query: 549 GGSGFSASSG---RGLGVGFGSGGGSSSSVKFVSTTSSSRKS 587
             SG  +SSG      G G+ SGGG S+S++F  TTSSS+ S
Sbjct: 594 SHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQHS 635


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  684 bits (1766), Expect = 0.0
 Identities = 391/645 (60%), Positives = 457/645 (70%), Gaps = 67/645 (10%)

Query: 1   MSRQ--SSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGG-----GGFGRVSLAG 53
           MSRQ  S   +RSGG  S  +A  I     RT+ +S  RSGGGGG     GG G    AG
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQ-RRTTSSSTRRSGGGGGRFSSCGGGGGSFGAG 59

Query: 54  ACGVGGYGSRSLYNLGGSKRISISTS-----GGSFRNRFGAGAGGGYGFGGGAGSGFGFG 108
               GG+GSRSL NLGGSK ISIS +     G  F   +G G  GG GFGGG   G G G
Sbjct: 60  ----GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIG 115

Query: 109 GGAGGGFGLGGGAGFGGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQR 163
           GG  GGFG GGG   GGGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+
Sbjct: 116 GGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQK 175

Query: 164 VRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYI 223
           V++ EREQIK+LNN+FASFIDKVRFLEQQN+VL TKW LLQ+  T T   NLEP FE +I
Sbjct: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235

Query: 224 NNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAY 283
           NNLRR++D +  ++ RLDSEL+NMQD+VED++NKYEDEINKRT AENEFV +KKDVD AY
Sbjct: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295

Query: 284 MNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVK 343
           M KV+L+AK+D L  EI+F+   + AELSQMQT +S+T+V+LSMDNNR+LDLDSIIAEVK
Sbjct: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355

Query: 344 AQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNV 403
           AQYE+IA +S+ EAES YQ+KYEELQ TAGRHGD +RN+K EISE+NR+IQRLR+EIDNV
Sbjct: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415

Query: 404 KKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLAL 463
           KKQ +NLQ +I+DAEQRGE ALKDA+NKL +LE+ALQ+AK+D+ARLLR+YQELMNTKLAL
Sbjct: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475

Query: 464 DVEIATYRKLLEGEECRLSGEGVGPVNISVVTS--SVSSG-------------------- 501
           D+EIATYR LLEGEE R+SGE    V++SV TS  ++S G                    
Sbjct: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSG 535

Query: 502 ---YGSGSGYGGGLG---------GGLGGGLGGGLAGGSSGSYYSSSS-----GGVGLGG 544
              YGSG G GGG G         G  GG  G G  GG  GSY S SS     GG G GG
Sbjct: 536 GGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG 595

Query: 545 GLSVG--GSGFSASSGRGLGVGFGSGG----GSSSSVKFVSTTSS 583
           G S G  GSG  +S G   G G  SGG    G SSSVKFVSTT S
Sbjct: 596 GGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYS 640


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  654 bits (1686), Expect = 0.0
 Identities = 358/575 (62%), Positives = 422/575 (73%), Gaps = 65/575 (11%)

Query: 12  GGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGS 71
           GG R FS  SAI     R +F+SVS SGG           AG C  GG+GSRSLYNL G+
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGG-----------AGRCSSGGFGSRSLYNLRGN 132

Query: 72  KRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPG 131
           K IS+S +G    +R GA  GG  GFG G     GFGGG GG F          G GGPG
Sbjct: 133 KSISMSVAG----SRQGACFGGAGGFGTG-----GFGGGFGGSFS---------GKGGPG 174

Query: 132 FPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQ 191
           FPVCP GGIQEVT+NQSLLTPL+++IDP IQ+VRTEEREQIK LNNKFASFIDKV+FLEQ
Sbjct: 175 FPVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQ 234

Query: 192 QNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLV 251
           QNKVL+TKW LLQ+Q T T  +NLEPLFE Y++ LR+QLD++  ++GRL SEL+ MQD V
Sbjct: 235 QNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSV 294

Query: 252 EDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAEL 311
           EDFK KYE+EINKRT AEN+FV+LKKDVDAAY+NKVELEAKVD+L DEINF+K+ +DAEL
Sbjct: 295 EDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAEL 354

Query: 312 SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQT 371
           SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEV+AQYEEIA RS+ EAE+ YQTK ++LQ +
Sbjct: 355 SQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQIS 414

Query: 372 AGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNK 431
             +HGD+L+NTK EI+E+NRMIQRLRAEI+N+KKQC  LQ ++ADAEQRGE ALKDA +K
Sbjct: 415 VDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSK 474

Query: 432 LAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNI 491
             ELE ALQ+AK+++AR+LREYQELM+ KLALD+EIATYRKLLEGEE R+SGE    V+I
Sbjct: 475 RVELEAALQQAKEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSI 534

Query: 492 SVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGS 551
           SVV+ S S+G     G  GGLG G G GL  G   GS                     GS
Sbjct: 535 SVVSGSTSTG-----GISGGLGSGSGFGLSSGFGSGS---------------------GS 568

Query: 552 GFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRK 586
           GF          GFG     SSS K +STT+ +++
Sbjct: 569 GF----------GFGGSVSGSSSSKIISTTTLNKR 593


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  647 bits (1669), Expect = 0.0
 Identities = 359/580 (61%), Positives = 421/580 (72%), Gaps = 29/580 (5%)

Query: 12  GGSRSFSTASAITPSVSR---TSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNL 68
           GG R FS+ SA+    SR   +SF+ +SR GGGGGG           G GG+GSRSL  L
Sbjct: 17  GGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGG----------FGGGGFGSRSLVGL 66

Query: 69  GGSKRISISTSGGS--------FRNRFGAGAGGGYGFGGGAG-SGFGFGGGA--GGGFGL 117
           GG+K ISIS +GG         F  R G G GGG  FGGG+G SG GFGGG   GG FG 
Sbjct: 67  GGTKSISISVAGGGGGFGAAGGFGGR-GGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGG 125

Query: 118 GGGAGFGGGFGGPGF--PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTL 175
            GG G  GG GGPG   P   PGGI EV+VNQSLL PLN+++DP IQ V+ +EREQIKTL
Sbjct: 126 FGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTL 185

Query: 176 NNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVG 235
           NNKFASFIDKVRFLEQQN+VL TKW LLQ+    T   NLEP+F+ YI++L+R LD +  
Sbjct: 186 NNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTA 245

Query: 236 ERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDA 295
           ER   +SEL NMQDLVED+K KYEDEINKRT AEN+FV LKKDVD AYM KVEL++KVD 
Sbjct: 246 ERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDL 305

Query: 296 LMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRT 355
           L  EI F+K+ +DAE+SQ+   V+DT+V+LSMDN+RNLDLDSIIAEVKAQYEEIA RS+ 
Sbjct: 306 LNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKE 365

Query: 356 EAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIA 415
           EAE+ Y +KYEELQ T GRHGD L+  K EISE+NR+IQRL+ EI +VKKQC N+Q+AIA
Sbjct: 366 EAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIA 425

Query: 416 DAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLE 475
           DAEQRGE ALKDARNKL +LEEALQ+AK+D+ARLLR+YQELMN KLALDVEIATYRKLLE
Sbjct: 426 DAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLE 485

Query: 476 GEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYG--GGLGGGLGGGLGGGLAGGSSGSYY 533
           GEECR+SG+    V +SV +S++SS   S + +G  GG G   GGG   G +   SG   
Sbjct: 486 GEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQ 545

Query: 534 SSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSS 573
           S S GG G GG +S GG G    SG   G G GS GGS S
Sbjct: 546 SGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSIS 585



 Score = 64.7 bits (156), Expect = 2e-10
 Identities = 50/130 (38%), Positives = 66/130 (50%), Gaps = 27/130 (20%)

Query: 20  ASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGS-RSLYNLGGSKRISIST 78
           +S +T SV+ ++ +S   S    GG  GR S +G    GGY S  S Y  GG +  S   
Sbjct: 496 SSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSG----GGYSSGSSSYGSGGRQSGSRGG 551

Query: 79  SGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGA------GGGFG-------LG----GGA 121
           SGG      G+ +GGGYG GGG+G  +G GGG+      GGG+G        G    GG+
Sbjct: 552 SGGG-----GSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGS 606

Query: 122 GFGGGFGGPG 131
             GGG+G  G
Sbjct: 607 SSGGGYGSGG 616



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 49/141 (34%), Positives = 64/141 (45%), Gaps = 18/141 (12%)

Query: 10  RSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGG----GGFGRVSLAGACGVGGYGSRSL 65
           R  G  S +   ++T S   ++  S +  GG GG     G G  S + + G GG  S S 
Sbjct: 490 RMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSR 549

Query: 66  YNLGGSKRISIST--SGGSFRNRFGAG--------AGGGYGFGGG---AGSGFGFGGGAG 112
              GG   IS     SGG    R+G+G        +GGGYG GGG   +G G   G  +G
Sbjct: 550 GGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSG 609

Query: 113 GGFG-LGGGAGFGGGFGGPGF 132
           GG+G  GGG+    G  G  F
Sbjct: 610 GGYGSGGGGSSSVKGSSGEAF 630



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 46/122 (37%), Positives = 56/122 (45%), Gaps = 11/122 (9%)

Query: 5   SSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGG--GGGGGFGRVSLAGACGVGGYGS 62
           S  +F   G R  S+    +   S  S+ S  R  G  GG GG G +S  G    GG G 
Sbjct: 514 SKAAFGGSGGRGSSSGGGYSSGSS--SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGG 571

Query: 63  RSLYNLGGSKRISISTSG---GSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119
           R   + GGSK  SIS  G   G  ++  G G+ GG   GGG GSG   GGG+    G  G
Sbjct: 572 R-YGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSG---GGGSSSVKGSSG 627

Query: 120 GA 121
            A
Sbjct: 628 EA 629



 Score = 53.1 bits (126), Expect = 7e-07
 Identities = 46/112 (41%), Positives = 55/112 (49%), Gaps = 17/112 (15%)

Query: 6   SVSFRSGGSRSFSTA-SAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRS 64
           S S+ SGG +S S   S    S+S   + S   SGG  G G G  S  G+   GGYGS  
Sbjct: 536 SSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG--SKGGSISGGGYGS-- 591

Query: 65  LYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFG 116
               GG K    S+ GGS   R G+ +GGGYG GGG  S     G +G  FG
Sbjct: 592 ----GGGKH---SSGGGS---RGGSSSGGGYGSGGGGSS--SVKGSSGEAFG 631



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/107 (36%), Positives = 42/107 (39%), Gaps = 31/107 (28%)

Query: 491 ISVVTSSVSSGYGSGSGYGGGLGGGLG-------------------GGLGGGLAGGSSGS 531
           +S   S  S G G G G   G   G                     GG GGG  GG  G 
Sbjct: 1   MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFG- 59

Query: 532 YYSSSSGGVGLGGGLSV------GGSGFSASSGRGLGVGFGSGGGSS 572
               S   VGLGG  S+      GG GF A+ G G G G G GGGSS
Sbjct: 60  ----SRSLVGLGGTKSISISVAGGGGGFGAAGGFG-GRGGGFGGGSS 101



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 23/59 (38%), Positives = 27/59 (45%), Gaps = 1/59 (1%)

Query: 526 GGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVG-FGSGGGSSSSVKFVSTTSS 583
           GG  G +   SSG   + GG     S FS  S  G G G FG GG  S S+  +  T S
Sbjct: 13  GGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKS 71



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 19/38 (50%), Positives = 20/38 (52%), Gaps = 1/38 (2%)

Query: 499 SSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSS 536
           SSG GS  G   G G G GGG G     GSSG  + SS
Sbjct: 597 SSGGGSRGGSSSGGGYGSGGG-GSSSVKGSSGEAFGSS 633


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  616 bits (1589), Expect = e-176
 Identities = 349/593 (58%), Positives = 423/593 (71%), Gaps = 45/593 (7%)

Query: 14  SRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLA-GACGVGGYG-------SRSL 65
           S  FS+ SA +    R   TS S   GGG    G V  A G CG GGYG       SRSL
Sbjct: 2   SHQFSSQSAFSSMSRRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSL 61

Query: 66  YNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG--GAGF 123
           YNLGGS+ ISI+  G   R+  G   GGG G G G G GFG G    GGFG GG  GAGF
Sbjct: 62  YNLGGSRSISINLMG---RSTSGFCQGGGVG-GFGGGRGFGVGSTGAGGFGGGGFGGAGF 117

Query: 124 G-GGFGGPGF-PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
           G   FG  GF P CPPGGIQEVT+NQSLL PL+L++DP IQR++T+EREQI  LNNKFAS
Sbjct: 118 GTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQIMVLNNKFAS 177

Query: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
           FIDKVRFLEQQN+VL TKW LLQ+  T T   NLEPL E YI +LRRQ+D +  E+ R +
Sbjct: 178 FIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDLLSAEQMRQN 237

Query: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
           +E+R+MQD+VED+K+KYEDEINKRT +EN+FV+LKKDVDAAY++KV+LE++VD L  E+N
Sbjct: 238 AEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESRVDTLTGEVN 297

Query: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
           F+K  F  ELSQ+QTH+SDT+V+LSMDNNR+LDLDSII  V+ QYE IA RS+ EAE+ Y
Sbjct: 298 FLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQRSKDEAEALY 357

Query: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
           QTKY+ELQ TAGRHGDDL+N+K EI+E+NR +QRL+AEI NVKKQ   +Q+ I+DAE+RG
Sbjct: 358 QTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQSLISDAEERG 417

Query: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
           E AL+DA  KL +LEEALQ++K+++ARLLR+YQ ++  KL+LDVEIATYR+LLEGEE R+
Sbjct: 418 EQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQLLEGEESRM 477

Query: 482 SGEGVGPVNISVVTSSVS--------SGYGSGSGYGGGLGGGLGGGLG--GGLAGGSSGS 531
           SGE    V+ISV  S VS          YGSG GYGGG GGG GGG    GG A G SG 
Sbjct: 478 SGELQSHVSISVQNSQVSVNGGAGGGGSYGSG-GYGGGSGGGYGGGRSYRGGGARGRSGG 536

Query: 532 YYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSS 584
            Y S  G    GGG S GGSG    SGRG           SS V+ + T++++
Sbjct: 537 GYGSGCG----GGGGSYGGSG---RSGRG-----------SSRVQIIQTSTNT 571


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  610 bits (1572), Expect = e-174
 Identities = 338/544 (62%), Positives = 398/544 (73%), Gaps = 40/544 (7%)

Query: 4   QSSVS---FRSGGSRSFSTASAITPSVSRTSFTS--VSRSGGGGGGGFGRVSLAGACGVG 58
           +SSVS   + + G  S ++AS  + S +RTSF+S  VSRS G GGG           G G
Sbjct: 2   RSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAH------CGPGTG 55

Query: 59  GYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLG 118
           G+GSRSLYNLGG K IS+S +GG+   R    A GG+GFG  A  G G G    G     
Sbjct: 56  GFGSRSLYNLGGHKSISVSVAGGALLGR----ALGGFGFGSRAFMGQGAGRQTFG----- 106

Query: 119 GGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNK 178
                         P CPPGGIQEVTVNQSLLTPL+++IDP IQRVRT+EREQIKTLNNK
Sbjct: 107 --------------PACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNK 152

Query: 179 FASFIDKVRFLEQQNKVLDTKWTLLQEQGTK--TVRQNLEPLFEQYINNLRRQLDSIVGE 236
           FASFIDKVRFLEQQNKVL+TKW LLQEQG      R NLEPLFE Y+ ++R  LD +  E
Sbjct: 153 FASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSE 212

Query: 237 RGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDAL 296
           RGRLDSELRN+QDLVEDFKNKYEDEINK T AENEFV+LKKDVDAAYM +++L  KV  L
Sbjct: 213 RGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTL 272

Query: 297 MDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTE 356
             EI+F++  ++ ELSQ+QTHVS+T+VVLSMDNNRNLDLDSIIAEVKAQYE IA RSR E
Sbjct: 273 TQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAE 332

Query: 357 AESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIAD 416
           AE+WYQTKYEELQ TAG+HGD+LR+TK+EI+E+ R IQRL+ E D  KKQC  LQ AIA+
Sbjct: 333 AEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAE 392

Query: 417 AEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEG 476
           AEQRGELALKDA+ KL +L+ AL +AK+D+ RLLR+YQELMN KLALDVEIATYRKLLE 
Sbjct: 393 AEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLES 452

Query: 477 EECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLG-GGLGGGLGGGLAGGSSGSYYSS 535
           EE R+SGE    V+ISV  +S +   G  + +GGG+  GG GG   GG    S+   YS+
Sbjct: 453 EESRMSGECPSAVSISVTGNSTTVCGGGAASFGGGISLGGSGGATKGGF---STNVGYST 509

Query: 536 SSGG 539
             GG
Sbjct: 510 VKGG 513


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  582 bits (1499), Expect = e-166
 Identities = 318/590 (53%), Positives = 415/590 (70%), Gaps = 51/590 (8%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60
           MSRQ +    +     FS  SA+    S +S+    R+GG G  G             G+
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSGGSSSSY----RAGGKGLSG-------------GF 43

Query: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120
            SRSLY+LGG++ IS + + GS       G  GGYGFG G  SGF              G
Sbjct: 44  SSRSLYSLGGARSISFNVASGS-------GWAGGYGFGRGRASGFA-------------G 83

Query: 121 AGFGGGFGGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179
           + FG    G   P +CPPGGI +VT+N+SLL PLN+++DP IQ+VR +EREQIK LNNKF
Sbjct: 84  SMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKF 143

Query: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239
           ASFIDKVRFLEQQN+VL+TKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R R
Sbjct: 144 ASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVR 203

Query: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299
           LDSELR+++++VED+K +YE+EINKRTTAENEFV+LKKDVDAAY +KVEL+AKVDAL  E
Sbjct: 204 LDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGE 263

Query: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359
           I F K  ++ E +Q+Q+H+SDTS++LSMDNNRNLDLDSIIAEV+AQYEEIA +S+ EAE+
Sbjct: 264 IKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEA 323

Query: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419
            YQTK++ELQ  AGRHGDDL++TK+EISE+ R+IQRLR+EI++VKKQCANL+ AIADAEQ
Sbjct: 324 LYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQ 383

Query: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479
           RG+ ALKDAR KL ELE ALQ+AK+++AR+LREYQEL++ KL+LD+EIATYRKLLEGEEC
Sbjct: 384 RGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEEC 443

Query: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539
           R+SGE    V+ISV+ SS++   G+G+G+G                 G+ G + SS SGG
Sbjct: 444 RMSGEYTNSVSISVINSSMAGMAGTGAGFGFS-------------NAGTYGYWPSSVSGG 490

Query: 540 VGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSSVKFVSTTSSSRKSFK 589
             +  G  V GSG  +  G        +     S  K ++ +S ++K+ +
Sbjct: 491 YSMLPGGCVTGSGNCSPRGEARTRLGSASEFRDSQGKTLALSSPTKKTMR 540


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  568 bits (1463), Expect = e-162
 Identities = 312/546 (57%), Positives = 391/546 (71%), Gaps = 39/546 (7%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGY 60
           MSRQ ++   SG   +FS  SA+ P  +  S  S   +G G G GFG             
Sbjct: 1   MSRQLNIK-SSGDKGNFSVHSAVVPRKAVGSLASYCAAGRGAGAGFG------------- 46

Query: 61  GSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG 120
            SRSLY+LGG++RIS + +GG  R        GGYGF  G+G    +GGG   GF    G
Sbjct: 47  -SRSLYSLGGNRRISFNVAGGGVR-------AGGYGFRPGSG----YGGGRASGFA---G 91

Query: 121 AGFGGGFGGPG-FPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKF 179
           + FG    GP    VCPPGGI +VTVN+SLL PLN+++DP IQ+VR +EREQIK LN+KF
Sbjct: 92  SMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKF 151

Query: 180 ASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGR 239
           ASFIDKVRFLEQQN+VL+TKW LLQ+      ++NLEP+ E YI+NLR+QL+++ G+R R
Sbjct: 152 ASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVR 211

Query: 240 LDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDE 299
           LDSELR+M+DLVED+K +YE EIN+RTTAENEFV+LKKD DAAY  KVEL+AKVD+L  E
Sbjct: 212 LDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKE 271

Query: 300 INFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAES 359
           I F+K  +DAE++Q+QTH S+TSV+LSMDNNR+LDLDSIIAEV+  YEEIA +S+ EAE+
Sbjct: 272 IKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEA 331

Query: 360 WYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQ 419
            YQTK +ELQ  A RHGDDL++T+ E+ E+NR+IQR+R EI NVKKQ A+L+ AIADAEQ
Sbjct: 332 LYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQ 391

Query: 420 RGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEEC 479
           RG+ ALKDA+ KL ELE AL +AK+++AR+LREYQELM+ KLALD+EIATYRKLLEGEEC
Sbjct: 392 RGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEEC 451

Query: 480 RLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGG 539
           R+SGE    V+ISV++SS  S +   S          G  LG     GSSGS  S  +  
Sbjct: 452 RMSGENPSSVSISVISSSSYSYHHPSSA---------GVDLGASAVAGSSGSTQSGQTKT 502

Query: 540 VGLGGG 545
               GG
Sbjct: 503 TEARGG 508



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 23/69 (33%), Positives = 26/69 (37%), Gaps = 3/69 (4%)

Query: 510 GGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGL---GGGLSVGGSGFSASSGRGLGVGFG 566
           G L      G G G   GS   Y    +  +     GGG+  GG GF   SG G G   G
Sbjct: 29  GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASG 88

Query: 567 SGGGSSSSV 575
             G    SV
Sbjct: 89  FAGSMFGSV 97


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  567 bits (1460), Expect = e-161
 Identities = 315/582 (54%), Positives = 402/582 (69%), Gaps = 63/582 (10%)

Query: 1   MSRQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGV-GG 59
           MSRQ +    +     FS  SA+    S +SF                   AG+ G+ GG
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFR------------------AGSKGLSGG 42

Query: 60  YGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGG 119
           +GSRSLY+LGG + +++++         G+G  GGYGFG G  SGF              
Sbjct: 43  FGSRSLYSLGGVRSLNVAS---------GSGKSGGYGFGRGRASGFA------------- 80

Query: 120 GAGFGGGFGGPGFP-VCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNK 178
           G+ FG    GP  P VCPPGGI +VTVN+SLL PLN+++DP IQ+VR +EREQIK LNNK
Sbjct: 81  GSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNK 140

Query: 179 FASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERG 238
           FASFIDKVRFLEQQN+VL+TKW LLQ+      + NLEP+ E YI+NLR+QL+++ G+R 
Sbjct: 141 FASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRV 200

Query: 239 RLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMD 298
           RLDSELRN++D+VED+K +YE+EINKRT AENEFV+LKKDVDAAY NKVEL+AKV+++  
Sbjct: 201 RLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQ 260

Query: 299 EINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAE 358
           EI F +  F+AE++Q+Q+H+SD SV+LSMDNNRNLDLDSII EV+ QYEEIA +S+ EAE
Sbjct: 261 EIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAE 320

Query: 359 SWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAE 418
           + YQTK++ELQ  AGRHGDDL+NTK+EISE+ R+IQR+R+EI+NVKKQ +NL+ AIADAE
Sbjct: 321 ALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAE 380

Query: 419 QRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEE 478
           QRG+ ALKDAR KL ELE AL +AK+++AR+LREYQELM+ KLALD+EIATYRKLLE EE
Sbjct: 381 QRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEE 440

Query: 479 CRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSG 538
           CR+SGE   PV+IS+++S+                   GG + G      SG Y ++SS 
Sbjct: 441 CRMSGEFPSPVSISIISST------------------SGGSVYGFRPSMVSGGYVANSSN 482

Query: 539 GVGLGGGLSV-GGSGFSASSGRGLGVGFGSGGGSSSSVKFVS 579
            +   G  SV GG G S  S        G G   S+  K  S
Sbjct: 483 CI--SGVCSVRGGEGRSRGSANDYKDTLGKGSSLSAPSKKTS 522


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  547 bits (1410), Expect = e-156
 Identities = 295/490 (60%), Positives = 365/490 (74%), Gaps = 31/490 (6%)

Query: 25  PSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFR 84
           P   R  F+  S    GG G       A   G   +GS+SL  LGGS+ +++S +     
Sbjct: 9   PRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARR-- 66

Query: 85  NRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFP-VCPPGGIQEV 143
                                  GGG  GGF    G  FG    GP  P VCPPGGI +V
Sbjct: 67  -----------------------GGGRLGGF---VGTAFGSAGLGPKCPSVCPPGGIPQV 100

Query: 144 TVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLL 203
           TVN+SLL PLN+++DP IQRVR +EREQIK LNNKFASFIDKVRFLEQQN+VL+TKW LL
Sbjct: 101 TVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL 160

Query: 204 QEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEIN 263
           Q+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED+K +YE EIN
Sbjct: 161 QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEIN 220

Query: 264 KRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSV 323
           +RT AENEFV+LKKDVDAAYMNKVEL+AKVD+L DEI F K  ++ E++Q+Q+H+SDTS+
Sbjct: 221 RRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSI 280

Query: 324 VLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTK 383
           VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+ EAE+ YQTK +ELQ TAG+HGDDL+ TK
Sbjct: 281 VLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTK 340

Query: 384 HEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAK 443
            EISE+NR+IQR+R+EI NVKKQCA+L+ AIADAEQRG+ ALKDAR KL ELE AL +AK
Sbjct: 341 AEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAK 400

Query: 444 QDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYG 503
           +++AR+LREYQEL++ KLALD+EIATYRKLLE EECR+SGE    V+ISV+ SS ++G G
Sbjct: 401 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI-SSTNAGAG 459

Query: 504 SGSGYGGGLG 513
            G+G+  G G
Sbjct: 460 -GAGFSMGFG 468



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 9/80 (11%)

Query: 5   SSVSFRSG--GSRSFSTASAITPSVSRT-SFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           SS SFR+   GS SF + S      SR+ + ++ +R GGG  GGF    +  A G  G G
Sbjct: 30  SSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGF----VGTAFGSAGLG 85

Query: 62  SR--SLYNLGGSKRISISTS 79
            +  S+   GG  +++++ S
Sbjct: 86  PKCPSVCPPGGIPQVTVNKS 105


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  547 bits (1410), Expect = e-156
 Identities = 295/490 (60%), Positives = 365/490 (74%), Gaps = 31/490 (6%)

Query: 25  PSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFR 84
           P   R  F+  S    GG G       A   G   +GS+SL  LGGS+ +++S +     
Sbjct: 9   PRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARR-- 66

Query: 85  NRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFP-VCPPGGIQEV 143
                                  GGG  GGF    G  FG    GP  P VCPPGGI +V
Sbjct: 67  -----------------------GGGRLGGF---VGTAFGSAGLGPKCPSVCPPGGIPQV 100

Query: 144 TVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLL 203
           TVN+SLL PLN+++DP IQRVR +EREQIK LNNKFASFIDKVRFLEQQN+VL+TKW LL
Sbjct: 101 TVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL 160

Query: 204 QEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEIN 263
           Q+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED+K +YE EIN
Sbjct: 161 QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEIN 220

Query: 264 KRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSV 323
           +RT AENEFV+LKKDVDAAYMNKVEL+AKVD+L DEI F K  ++ E++Q+Q+H+SDTS+
Sbjct: 221 RRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSI 280

Query: 324 VLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTK 383
           VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+ EAE+ YQTK +ELQ TAG+HGDDL+ TK
Sbjct: 281 VLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTK 340

Query: 384 HEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAK 443
            EISE+NR+IQR+R+EI NVKKQCA+L+ AIADAEQRG+ ALKDAR KL ELE AL +AK
Sbjct: 341 AEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAK 400

Query: 444 QDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYG 503
           +++AR+LREYQEL++ KLALD+EIATYRKLLE EECR+SGE    V+ISV+ SS ++G G
Sbjct: 401 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI-SSTNAGAG 459

Query: 504 SGSGYGGGLG 513
            G+G+  G G
Sbjct: 460 -GAGFSMGFG 468



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 9/80 (11%)

Query: 5   SSVSFRSG--GSRSFSTASAITPSVSRT-SFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           SS SFR+   GS SF + S      SR+ + ++ +R GGG  GGF    +  A G  G G
Sbjct: 30  SSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGF----VGTAFGSAGLG 85

Query: 62  SR--SLYNLGGSKRISISTS 79
            +  S+   GG  +++++ S
Sbjct: 86  PKCPSVCPPGGIPQVTVNKS 105


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  539 bits (1389), Expect = e-153
 Identities = 325/619 (52%), Positives = 407/619 (65%), Gaps = 68/619 (10%)

Query: 11  SGGSR--SFSTASAITP-SVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYN 67
           S G R  +FS+ SA+TP +++R    SVS   G            G  G+G +GSRS+  
Sbjct: 9   SSGHRVGNFSSCSAMTPQNLNRFRANSVSCWSG-----------PGFRGLGSFGSRSVIT 57

Query: 68  LGG-SKRISISTSGGSFRN-RFGAGAGGGYGFGGGAGSG------FGFGGGAGGGFGLG- 118
            G  S RI+   S       RFGAG G G+G G G G G       G G GAG G G G 
Sbjct: 58  FGSYSPRIAAVGSRPIHCGVRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGF 117

Query: 119 GGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNK 178
           GG GFG   GG G P  P   I  VTVN+SLLTPLNL+IDP+ QRV+ +E+EQIKTLNNK
Sbjct: 118 GGPGFGYRVGGVGVPAAP--SITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNK 175

Query: 179 FASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERG 238
           FASFIDKVRFLEQQNK+L+TKW+ LQEQ  K +R NLEPLFE YI NLRRQL+ +V ++ 
Sbjct: 176 FASFIDKVRFLEQQNKLLETKWSFLQEQ--KCIRSNLEPLFESYITNLRRQLEVLVSDQA 233

Query: 239 RLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMD 298
           RL +E  ++QD++E FK KYE+E+  R  AENEFV LKKDVDAA+MNK +LEA VD L  
Sbjct: 234 RLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQ 293

Query: 299 EINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAE 358
           EI+F+K  +  E+  +Q+H+S+TSV++ MDN+R+L+LD IIAEVKAQYEE+A RSR +AE
Sbjct: 294 EIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAE 353

Query: 359 SWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAE 418
           +WYQTKYEE+Q TAG+H D+LRN ++EI+E+ R+IQRL+AEI++ K Q A L+ A+A+AE
Sbjct: 354 AWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAE 413

Query: 419 QRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEE 478
           Q+GE  L DA+ KLA+LE ALQ+AKQDMAR L EYQELMN KL LD+EIATYR+LLEGEE
Sbjct: 414 QQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEE 473

Query: 479 CRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGS---SGSYYSS 535
            RL  EGVGPVNISV            S  GG + G      G  L+ G    SGS    
Sbjct: 474 SRLC-EGVGPVNISV-----------SSSRGGLVCGPEPLVAGSTLSRGGVTFSGSSSVC 521

Query: 536 SSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSG--------------------------G 569
           ++ GV    G S+GG+  + ++G  L  G  SG                          G
Sbjct: 522 ATSGVLASCGPSLGGARVAPATGDLLSTGTRSGSMLISEACVPSVPCPLPTQGGFSSCSG 581

Query: 570 GSSSSVKFVSTTSSSRKSF 588
           G SSSV+FVSTT+S R  +
Sbjct: 582 GRSSSVRFVSTTTSCRTKY 600


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  526 bits (1356), Expect = e-149
 Identities = 297/487 (60%), Positives = 353/487 (72%), Gaps = 20/487 (4%)

Query: 74  ISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG-AGFGGGFGGPGF 132
           +SI  S   F +R  A +G G      +    G G  +  G G           +GGP  
Sbjct: 1   MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGP-- 58

Query: 133 PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQ 192
                 GI+EVT+NQSLL PL L  DPS+QRVR EE EQIKTLNNKFASFIDKVRFLEQQ
Sbjct: 59  ---VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQ 115

Query: 193 NKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVE 252
           NK+L+TKWTLLQEQ +      L  +FE  I  LR QL+++  + GRL++ELR+MQD+VE
Sbjct: 116 NKLLETKWTLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVE 174

Query: 253 DFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELS 312
           DFKNKYEDEIN RT AENEFV+LKKDVDAAYM+KVELEAKVDAL DEINF++   + EL+
Sbjct: 175 DFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELT 234

Query: 313 QMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTA 372
           ++Q+ +SDTSVVLSMDN+R+LDLD IIAEVKAQYEE+A  SR EAE+WYQTK+E LQ  A
Sbjct: 235 ELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQA 294

Query: 373 GRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKL 432
           G+HGDDLRNT++EISEMNR IQRL+AEIDN+K Q A L+ AIA+AE+RGELALKDAR K 
Sbjct: 295 GKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQ 354

Query: 433 AELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNIS 492
            ELE ALQ+ KQDMAR LREYQELM+ KLALD+EIATYRKLLEGEE RL+G+GVG VNIS
Sbjct: 355 EELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNIS 414

Query: 493 VVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSG 552
           V+ S+       GS  GGG+G  LGG +G       S +   SSS G GL    S+  + 
Sbjct: 415 VMNST------GGSSSGGGIGLTLGGTMG-------SNALSFSSSAGPGLLKAYSIRTAS 461

Query: 553 FSASSGR 559
            S  S R
Sbjct: 462 ASRRSAR 468


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  526 bits (1354), Expect = e-149
 Identities = 289/471 (61%), Positives = 351/471 (74%), Gaps = 27/471 (5%)

Query: 72  KRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFG---FGGGAGGGFGLGGGAGFGGGFG 128
           K   +STSG    +     +G G      + S  G   F GG GGG+G  G +G GG   
Sbjct: 8   KSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYG--GASGMGG--- 62

Query: 129 GPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRF 188
                      I  VTVNQSLL+PL L++DP+IQ VRT+E+EQIKTLNNKFASFIDKVRF
Sbjct: 63  -----------ITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRF 111

Query: 189 LEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQ 248
           LEQQNK+L+TKW+LLQ+Q  KT R N++ +FE YINNLRRQL+++  E+ +L++EL NMQ
Sbjct: 112 LEQQNKMLETKWSLLQQQ--KTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQ 169

Query: 249 DLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFD 308
            LVEDFKNKYEDEINKRT  ENEFV++KKDVD AYMNKVELE++++ L DEINF++  ++
Sbjct: 170 GLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYE 229

Query: 309 AELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEEL 368
            E+ ++Q+ +SDTSVVLSMDN+R+LD+DSIIAEVKAQYE+IANRSR EAES YQ KYEEL
Sbjct: 230 EEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEEL 289

Query: 369 QQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDA 428
           Q  AG+HGDDLR TK EISEMNR I RL+AEI+ +K Q A+L+ AIADAEQRGELA+KDA
Sbjct: 290 QSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDA 349

Query: 429 RNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGP 488
             KL+ELE ALQ+AKQDMAR LREYQELMN KLALD+EIATYRKLLEGEE RL     G 
Sbjct: 350 NAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLES---GM 406

Query: 489 VNISVVTSSVSSGYGSG--SGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSS 537
            N+S+ T + +SGY  G  S YGG    GL   LG     G+  S +S +S
Sbjct: 407 QNMSIHTKT-TSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTS 456



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 25/61 (40%), Positives = 32/61 (52%), Gaps = 10/61 (16%)

Query: 4  QSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSG-----GGGGGGFGRVSLAGACGVG 58
          Q S    + G R+FS+ S  +   SR S +S SR G     GG GGG+G     GA G+G
Sbjct: 7  QKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYG-----GASGMG 61

Query: 59 G 59
          G
Sbjct: 62 G 62


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  493 bits (1268), Expect = e-139
 Identities = 278/543 (51%), Positives = 363/543 (66%), Gaps = 31/543 (5%)

Query: 49  VSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFG 108
           +SL+      G+ +RS  +     R     S G F +R G  +     FGG      G  
Sbjct: 1   MSLSPCRAQRGFSARSACSARSRGR-----SRGGFSSRGGFSSRSLNSFGGCLEGSRGST 55

Query: 109 GGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEE 168
            G+GG  G+     FG   GGPG  +CPPGGIQEVT+NQ+LLTPL ++IDP  Q VRT+E
Sbjct: 56  WGSGGRLGVR----FGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQE 111

Query: 169 REQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRR 228
            ++I+TLNN+FASFIDKVRFLEQQNKVL+TKW LLQ+QG    +Q LEP+FE  ++ LR+
Sbjct: 112 TQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRK 171

Query: 229 QLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVE 288
           QL+ + GERG LD+EL+  +D  E++K+KYE+E ++R T EN+FV+LKKDVD  +++K+E
Sbjct: 172 QLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKME 231

Query: 289 LEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEE 348
           LE K++AL + + F+K   + EL Q+QT  SDTSVVLSMDNNR LD  SII EV+A+YEE
Sbjct: 232 LEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEE 291

Query: 349 IANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCA 408
           IA  S+ EAE+ YQTKY+ELQ +A  HGD ++ TK +IS++++ IQRL+++ +N+KKQ A
Sbjct: 292 IARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNA 351

Query: 409 NLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIA 468
           +LQ AI DAEQRGELALKDA+ K+ ELE AL+ AKQ++ARLL EYQEL +TKL+LDVEIA
Sbjct: 352 SLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIA 411

Query: 469 TYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGS 528
           TYR+LLEGEECR+SGE    V IS V        G  +   GG+GGGLG   G G   GS
Sbjct: 412 TYRRLLEGEECRMSGECTSQVTISSV--------GGSAVMSGGVGGGLGSTCGLGSGKGS 463

Query: 529 SGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVG----FGSGGGSSSSVKFVSTTSSS 584
            GS  +S          +  GGS     SG+   +      GS  GSS       T  SS
Sbjct: 464 PGSCCTS----------IVTGGSNIILGSGKDPVLDSCSVSGSSAGSSCHTILKKTVESS 513

Query: 585 RKS 587
            K+
Sbjct: 514 LKT 516


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  468 bits (1203), Expect = e-132
 Identities = 265/490 (54%), Positives = 328/490 (66%), Gaps = 73/490 (14%)

Query: 25  PSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFR 84
           P   R  F+  S    GG G       A   G   +GS+SL  LGGS+ +++S +     
Sbjct: 9   PRGERLGFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARR-- 66

Query: 85  NRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFP-VCPPGGIQEV 143
                                  GGG  GGF    G  FG    GP  P VCPPGGI +V
Sbjct: 67  -----------------------GGGRLGGFV---GTAFGSAGLGPKCPSVCPPGGIPQV 100

Query: 144 TVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLL 203
           TVN+SLL PLN+++DP IQRVR +EREQIK LNNKFASFIDKVRFLEQQN+VL+TKW LL
Sbjct: 101 TVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLL 160

Query: 204 QEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEIN 263
           Q+      R+NLEP++E YI+NL++QL+ + G+  RLDSELRNMQDLVED+K +YE EIN
Sbjct: 161 QQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEIN 220

Query: 264 KRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSV 323
           +RT AENEFV+LKKDVDAAYMNKVEL+AKVD+L DEI F K  ++ E++Q+Q+H+SDTS+
Sbjct: 221 RRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSI 280

Query: 324 VLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTK 383
           VLSMDNNR+LDLDSIIAEV+AQYEEIA +S+ EAE+ YQTK                   
Sbjct: 281 VLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTK------------------- 321

Query: 384 HEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAK 443
                                  CA+L+ AIADAEQRG+ ALKDAR KL ELE AL +AK
Sbjct: 322 -----------------------CADLETAIADAEQRGDCALKDARAKLDELEGALHQAK 358

Query: 444 QDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYG 503
           +++AR+LREYQEL++ KLALD+EIATYRKLLE EECR+SGE    V+ISV+ SS ++G G
Sbjct: 359 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVI-SSTNAGAG 417

Query: 504 SGSGYGGGLG 513
            G+G+  G G
Sbjct: 418 -GAGFSMGFG 426



 Score = 30.0 bits (66), Expect = 6.2
 Identities = 27/80 (33%), Positives = 42/80 (52%), Gaps = 9/80 (11%)

Query: 5   SSVSFRSG--GSRSFSTASAITPSVSRT-SFTSVSRSGGGGGGGFGRVSLAGACGVGGYG 61
           SS SFR+   GS SF + S      SR+ + ++ +R GGG  GGF    +  A G  G G
Sbjct: 30  SSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRLGGF----VGTAFGSAGLG 85

Query: 62  SR--SLYNLGGSKRISISTS 79
            +  S+   GG  +++++ S
Sbjct: 86  PKCPSVCPPGGIPQVTVNKS 105


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  453 bits (1166), Expect = e-127
 Identities = 269/569 (47%), Positives = 361/569 (63%), Gaps = 66/569 (11%)

Query: 8   SFRSG---GSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGSRS 64
           SF+ G   GS+SFS+ SA+ P +   +  +VS+     GGG G  +L      G  GSRS
Sbjct: 5   SFQPGSRCGSQSFSSYSAVMPRM--VTHYAVSKGPCRPGGGRGLRAL------GCLGSRS 56

Query: 65  LYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGAGFG 124
           L N+G  +    S  GG+                     GFG+  GA  G          
Sbjct: 57  LCNVGFGRPRVASRCGGTL-------------------PGFGYRLGATCG---------- 87

Query: 125 GGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFID 184
                      P   I  VT+N+SLL PL L+IDP++QRV+ +E+EQIK LNN+FASFI+
Sbjct: 88  -----------PSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFIN 136

Query: 185 KVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSEL 244
           KVRFLEQ+NK+L+TKW  +Q+Q  +  + N+EP+FE YI+ LRRQLD + G+R RL+SEL
Sbjct: 137 KVRFLEQKNKLLETKWNFMQQQ--RCCQTNIEPIFEGYISALRRQLDCVSGDRVRLESEL 194

Query: 245 RNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMK 304
            ++Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K +LE   +AL+ EI+F+K
Sbjct: 195 CSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLK 254

Query: 305 MFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTK 364
             ++ E+  +Q+ +S+TSV++ MDN+R LD+D IIAE+KAQY++IA+RS+ EAE+WYQ +
Sbjct: 255 SLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCR 314

Query: 365 YEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELA 424
           YEEL+ TAG H D+LRN K+EI EMN++IQRL+ E +NVK Q   L+ AIA+AEQ+GE A
Sbjct: 315 YEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAA 374

Query: 425 LKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGE 484
           L DA+ KLA LEEALQKAKQDMA LL+EYQE+MN+KL LD+EIATYR+LLEGEE RL  E
Sbjct: 375 LNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLC-E 433

Query: 485 GVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGG 544
           G+GPVNISV +S  +  Y         L  G+    GG    G+   Y      G+    
Sbjct: 434 GIGPVNISVSSSKGAFLYEPCGVSTPVLSTGVLRSNGGCSIVGTGELYVPCEPQGL---- 489

Query: 545 GLSVGGSGFSASSGRGLGVGFGSGGGSSS 573
                    S  SGR   +  G+GG S S
Sbjct: 490 --------LSCGSGRKSSMTLGAGGSSPS 510


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  452 bits (1164), Expect = e-127
 Identities = 266/550 (48%), Positives = 353/550 (64%), Gaps = 77/550 (14%)

Query: 3   RQSSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGGGGFGRVSLAGACGVGGYGS 62
           R   +S   G +R+FS+ SA+ P        S +   G          ++   G+ G+GS
Sbjct: 4   RSYRISSGCGVTRNFSSCSAVAPKTGNRCCISAAPYRG----------VSCYRGLTGFGS 53

Query: 63  RSLYNLGG-SKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGGA 121
           RSL NLG    RI++    G FR              G  G  FG+              
Sbjct: 54  RSLCNLGSCGPRIAV----GGFR-------------AGSCGRSFGYR------------- 83

Query: 122 GFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFAS 181
              GG  GP  P C    I  V+VN+SLLTPLNL+IDP+ Q V+ EE+EQIK+LN++FA+
Sbjct: 84  --SGGVCGPS-PPC----ITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAA 136

Query: 182 FIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLD 241
           FIDKVRFLEQQNK+L+TKW   Q Q  +    NLEPLF  YI  LRR+ + +  + GRL 
Sbjct: 137 FIDKVRFLEQQNKLLETKWQFYQNQ--RCCESNLEPLFSGYIETLRREAECVEADSGRLA 194

Query: 242 SELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEIN 301
           SEL ++Q+++E +K KYE+E+  R TAENEFV+LKKDVD AY+ K +LEA V+AL++E +
Sbjct: 195 SELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSDLEANVEALVEESS 254

Query: 302 FMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWY 361
           F++  ++ E+  +Q H+SDTSV++ MDN+R+L++D IIAE+KAQY+++A+RSR EAESWY
Sbjct: 255 FLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDDVASRSRAEAESWY 314

Query: 362 QTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRG 421
           ++K EE++ T  RHG+ LR TK EI+E+NRMIQRL AEI+N K Q A L+ A+A+AEQ+G
Sbjct: 315 RSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRAKLEAAVAEAEQQG 374

Query: 422 ELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRL 481
           E AL DAR KLAELE ALQKAKQDMA LL+EYQE+MN+KL LD+EIATYR+LLEGEE RL
Sbjct: 375 EAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRL 434

Query: 482 SGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVG 541
             EGVG VN+ V +S                    GG   GGL+       YS++ G   
Sbjct: 435 C-EGVGSVNVCVSSSR-------------------GGVSCGGLS-------YSTTPGRQI 467

Query: 542 LGGGLSVGGS 551
             G  ++GGS
Sbjct: 468 TSGPSAIGGS 477


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  437 bits (1124), Expect = e-122
 Identities = 255/492 (51%), Positives = 335/492 (68%), Gaps = 28/492 (5%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNM 271

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
           +MN+KL LD+EIATYR+LLEGEE RL  EG+G VN+ V +S                GG 
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGIGAVNVCVSSSR---------------GGV 435

Query: 516 LGGGLGGGLAGGSSGSYYSS-SSGGVGLGGGLSVGGSGFSASSGRGLGVGFGSGGGSSSS 574
           + G L    +   +GS  S+  +G V +  GL       + + G G   G GS G SS  
Sbjct: 436 VCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGG-SCGVGSCGISSLG 494

Query: 575 VKFVSTTSSSRK 586
           V   S  SS RK
Sbjct: 495 VG--SCGSSCRK 504


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  436 bits (1122), Expect = e-122
 Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
           +MN+KL LD+EIATYR+LLEGEE RL  EGVG VN+ V +S                   
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432

Query: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567
            GG + G L   ++    S+    V     + VG +   A S R +GV  GS
Sbjct: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  436 bits (1122), Expect = e-122
 Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
           +MN+KL LD+EIATYR+LLEGEE RL  EGVG VN+ V +S                   
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432

Query: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567
            GG + G L   ++    S+    V     + VG +   A S R +GV  GS
Sbjct: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  436 bits (1122), Expect = e-122
 Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
           +MN+KL LD+EIATYR+LLEGEE RL  EGVG VN+ V +S                   
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432

Query: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567
            GG + G L   ++    S+    V     + VG +   A S R +GV  GS
Sbjct: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  436 bits (1122), Expect = e-122
 Identities = 246/472 (52%), Positives = 324/472 (68%), Gaps = 29/472 (6%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 40  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 93

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 94  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 151

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLFE YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E++ R TAENEFV L
Sbjct: 152 EPLFEGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVAL 211

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 212 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNM 271

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D IIAE+KAQY++I  RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 272 DCIIAEIKAQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 331

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 332 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 391

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGG 515
           +MN+KL LD+EIATYR+LLEGEE RL  EGVG VN+ V +S                   
Sbjct: 392 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSSR------------------ 432

Query: 516 LGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVGFGS 567
            GG + G L   ++    S+    V     + VG +   A S R +GV  GS
Sbjct: 433 -GGVVCGDLCASTTAPVVSTRVSSVPSNSNVVVGTTNACAPSAR-VGVCGGS 482


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  428 bits (1101), Expect = e-120
 Identities = 229/401 (57%), Positives = 300/401 (74%), Gaps = 9/401 (2%)

Query: 96  GFGGGAGSGFGFGGGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNL 155
           G  GG GS    GG   G  G   G    GG  GP  P C    I  V+VN+SLLTPLNL
Sbjct: 45  GLTGGFGSHSVCGGFRAGSCGRSFGYR-SGGVCGPS-PPC----ITTVSVNESLLTPLNL 98

Query: 156 QIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNL 215
           +IDP+ Q V+ EE+EQIK+LN++FA+FIDKVRFLEQQNK+L+TK    Q +  +  + NL
Sbjct: 99  EIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNR--ECCQSNL 156

Query: 216 EPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVML 275
           EPLF  YI  LRR+ + +  + GRL SEL ++Q+++E +K KYE+E+  R TAENEFV L
Sbjct: 157 EPLFAGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVAL 216

Query: 276 KKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDL 335
           KKDVD AY+ K +LEA V+AL+ EI+F++  ++ E+  +Q+H+SDTSVV+ +DN+R+L++
Sbjct: 217 KKDVDCAYLRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNM 276

Query: 336 DSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQR 395
           D I+AE+KAQY++IA RSR EAESWY++K EE++ T  RHG+ LR TK EI+E+NRMIQR
Sbjct: 277 DCIVAEIKAQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 336

Query: 396 LRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQE 455
           L AE++N K Q + L+ A+A +EQ+GE AL DAR KLAELE ALQKAKQDMA L+REYQE
Sbjct: 337 LTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQE 396

Query: 456 LMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNISVVTS 496
           +MN+KL LD+EIATYR+LLEGEE RL  EGV  VN+ V +S
Sbjct: 397 VMNSKLGLDIEIATYRRLLEGEEQRLC-EGVEAVNVCVSSS 436


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.133    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,613,515
Number of Sequences: 37866
Number of extensions: 1250802
Number of successful extensions: 44608
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 572
Number of HSP's successfully gapped in prelim test: 722
Number of HSP's that attempted gapping in prelim test: 11667
Number of HSP's gapped (non-prelim): 13121
length of query: 590
length of database: 18,247,518
effective HSP length: 108
effective length of query: 482
effective length of database: 14,157,990
effective search space: 6824151180
effective search space used: 6824151180
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.