Search of human proteins with 119395750

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119395750 keratin 1 [Homo sapiens]
         (644 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119395750 keratin 1 [Homo sapiens]                                1284   0.0  
gi|47132620 keratin 2 [Homo sapiens]                                  763   0.0  
gi|109148552 keratin 3 [Homo sapiens]                                 697   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 684   0.0  
gi|153791670 keratin 76 [Homo sapiens]                                684   0.0  
gi|194018511 keratin 77 [Homo sapiens]                                675   0.0  
gi|119703753 keratin 6B [Homo sapiens]                                658   0.0  
gi|5031839 keratin 6A [Homo sapiens]                                  657   0.0  
gi|155969697 keratin 6C [Homo sapiens]                                655   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 600   e-171
gi|153791158 keratin 75 [Homo sapiens]                                584   e-167
gi|32567786 keratin 6L [Homo sapiens]                                 583   e-166
gi|28173564 keratin 73 [Homo sapiens]                                 559   e-159
gi|15618995 keratin 71 [Homo sapiens]                                 555   e-158
gi|148612803 keratin 6 irs4 [Homo sapiens]                            536   e-152
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       524   e-149
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      524   e-149
gi|4504919 keratin 8 [Homo sapiens]                                   473   e-133
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    472   e-133
gi|89357932 keratin 5b [Homo sapiens]                                 463   e-130
gi|67782365 keratin 7 [Homo sapiens]                                  452   e-127
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      411   e-115
gi|27477127 keratin 82 [Homo sapiens]                                 407   e-113
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   401   e-111
gi|4504935 keratin 85 [Homo sapiens]                                  397   e-110
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   394   e-109
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   394   e-109
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   394   e-109
gi|14318422 keratin 86 [Homo sapiens]                                 394   e-109
gi|169790841 keratin 83 [Homo sapiens]                                392   e-109

>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score = 1284 bits (3322), Expect = 0.0
 Identities = 644/644 (100%), Positives = 644/644 (100%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG
Sbjct: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
           GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG
Sbjct: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120

Query: 121 GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSRE 180
           GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSRE
Sbjct: 121 GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSRE 180

Query: 181 REQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRR 240
           REQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRR
Sbjct: 181 REQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRR 240

Query: 241 RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD 300
           RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD
Sbjct: 241 RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD 300

Query: 301 LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYED 360
           LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYED
Sbjct: 301 LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYED 360

Query: 361 IAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS 420
           IAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS
Sbjct: 361 IAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS 420

Query: 421 NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA 480
           NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA
Sbjct: 421 NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA 480

Query: 481 TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG 540
           TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG
Sbjct: 481 TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG 540

Query: 541 SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600
           SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG
Sbjct: 541 SGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600

Query: 601 GRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR 644
           GRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR
Sbjct: 601 GRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR 644


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  763 bits (1970), Expect = 0.0
 Identities = 424/651 (65%), Positives = 491/651 (75%), Gaps = 46/651 (7%)

Query: 1   MSRQFSSRSGYRSGGG-----FSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGS 55
           MS Q S +S  R GGG     FSSGSA +    RR+TSS +          S  GGGGG 
Sbjct: 1   MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSC--------LSRHGGGGGG 52

Query: 56  FGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGG--GGFGGG-------GFGG 106
           FG GGGFGSRSLV LGG+KSISISVA GGG G G  GG+GG  GGFGGG       GF G
Sbjct: 53  FG-GGGFGSRSLVGLGGTKSISISVAGGGG-GFGAAGGFGGRGGGFGGGSSFGGGSGFSG 110

Query: 107 GGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLN 166
           GGFGGGG GGG FGGFG      G GG GG G  GG+GP   PGGI EV++NQSLLQPLN
Sbjct: 111 GGFGGGGFGGGRFGGFG------GPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLN 164

Query: 167 VEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHN 226
           V++DPEIQ VK++EREQIK+LNN+FASFIDKVRFLEQQNQVLQTKWELLQQ++  TR  N
Sbjct: 165 VKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPIN 224

Query: 227 LEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVT 286
           LEP F+ +I++L+R +D L ++++  +SEL NMQD+VEDY+ KYEDEINKRT AEN+FVT
Sbjct: 225 LEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVT 284

Query: 287 IKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLD 346
           +KKDVD AYM KV+LQ+K+D L QEI+FL  LY AE+SQ+   +++TNVILSMDN+R+LD
Sbjct: 285 LKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLD 344

Query: 347 LDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQ 406
           LDSIIAEVKAQYE+IAQ+SK EAE+LY SKYEELQ+T GRHGDS++  KIEISELNRVIQ
Sbjct: 345 LDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQ 404

Query: 407 RLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQ 466
           RL+ EI +VKKQ  N+Q +I+DAEQRGE+ALKDA+NKLNDLE+ALQQAKEDLARLLRDYQ
Sbjct: 405 RLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQ 464

Query: 467 ELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSV--STSHTTISGGGSRGGGGGG 524
           ELMN KLALD+EIATYR LLEGEE RMSG+ + NV+VSV  ST  + ++   + GG GG 
Sbjct: 465 ELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGR 524

Query: 525 YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584
             S G  Y SG  SYGSGG   G RG  G GGS     GG YGSGGG GG   YGSG   
Sbjct: 525 GSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGS---ISGGGYGSGGGSGGR--YGSG--- 576

Query: 585 GGYRGGS-GGGGGGSSGGR-GSGGGSSGGSIGGRGSSSGGVKSSGGSSSVK 633
           GG +GGS  GGG GS GG+  SGGGS GGS  G G  SGG    GGSSSVK
Sbjct: 577 GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGG----GGSSSVK 623



 Score = 89.7 bits (221), Expect = 7e-18
 Identities = 65/152 (42%), Positives = 71/152 (46%), Gaps = 30/152 (19%)

Query: 517 SRGGGGGGYGSGGSSYGS--------------------GGGSYGSGGGGGGGRGSYGSGG 556
           SRG GGGG G  G S GS                    GGG  G GGGG G R   G GG
Sbjct: 9   SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68

Query: 557 S-----SYGSGGGSYGSGGGGGGHGS-YGSGSSSGGYRGGSGG--GGGGSSGGRGSGGGS 608
           +     S   GGG +G+ GG GG G  +G GSS GG  G SGG  GGGG  GGR  G G 
Sbjct: 69  TKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGG 128

Query: 609 SGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYS 640
            GG +GG G   GG    G    +  VS   S
Sbjct: 129 PGG-VGGLG-GPGGFGPGGYPGGIHEVSVNQS 158



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 5/70 (7%)

Query: 577 SYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSS-----GGSIGGRGSSSGGVKSSGGSSS 631
           S G G   GG+RG S G    S G R S    S     GG  GG G    G +S  G   
Sbjct: 9   SRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGG 68

Query: 632 VKFVSTTYSG 641
            K +S + +G
Sbjct: 69  TKSISISVAG 78



 Score = 34.7 bits (78), Expect = 0.28
 Identities = 23/59 (38%), Positives = 26/59 (44%), Gaps = 4/59 (6%)

Query: 7   SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGFGSR 65
           S  GY SGGG  S   G     R  +SS      GGGG  S  G  G +FG+   F  R
Sbjct: 585 SGGGYGSGGGKHSSGGG----SRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR 639


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  697 bits (1800), Expect = 0.0
 Identities = 406/634 (64%), Positives = 459/634 (72%), Gaps = 51/634 (8%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           MSRQ S  SG  S G FS  SA +    R    S    SGG GG      G  G     G
Sbjct: 1   MSRQASKTSGGGSQG-FSGRSAVVSGSSRM---SCVAHSGGAGG------GAYGFRSGAG 50

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGG---------YGGG---GFGGG---GFG 105
           GFGSRSL NLGG+KSISISVA GG R  GFGGG         YGGG   G+GGG   GFG
Sbjct: 51  GFGSRSLYNLGGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFG 110

Query: 106 GG-GFGGGGIGGGGFGGFGS--GGGGFGG-GGFGG-GGYGG--------GYGPVCPPGGI 152
           GG G GGG  G GGFGG G   G GGFGG GGFGG GG+GG        G+GP   PGGI
Sbjct: 111 GGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPGGFGPGGFPGGI 170

Query: 153 QEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKW 212
           QEVTINQSLLQPLNVEIDP+I +VK++EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW
Sbjct: 171 QEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 230

Query: 213 ELLQQVDTST--RTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKY 270
            LLQQ  TS+   T+NLEP FE+ IN LR  +D +  ++ RLDSELKNM+D+VED++ KY
Sbjct: 231 NLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDFKKKY 290

Query: 271 EDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQI 330
           EDEINKRT AENEFVT+KKDVD AYM KV+LQAK+D L  EIDFL  LY AELSQMQ+ I
Sbjct: 291 EDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQMQSHI 350

Query: 331 SETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDS 390
           S+T+V+LSMDNNRSLDLDSIIAEV+AQYEDIAQ+SKAEAE+LYQ+K  ELQ TAGRHGD 
Sbjct: 351 SDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDD 410

Query: 391 VRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDA 450
           +RN+K EI ELNR+IQRLR+EI+ VKKQ +NLQ +I++AEQ GE ALKDA  KL +L+ A
Sbjct: 411 LRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQELQAA 470

Query: 451 LQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHT 510
           LQQAK+DLARLLRDYQELMN KLALD+EIATYR LLEGEE RMSGEC   VS+SV +S T
Sbjct: 471 LQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVVSSST 530

Query: 511 TISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG 570
           T     S GG GGGYG GG   G GGG + +GGG G G G  G GG   G GGGS G  G
Sbjct: 531 T---SASAGGYGGGYG-GGMGGGLGGG-FSAGGGSGSGFGRGGGGGIGGGFGGGSSGFSG 585

Query: 571 GGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGS 604
           G       G GS SG   G SGGG   +S   GS
Sbjct: 586 GS------GFGSISGARYGVSGGGFSSASNRGGS 613



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 56/158 (35%), Positives = 70/158 (44%), Gaps = 22/158 (13%)

Query: 503 VSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS-----------------GGGSYGSGGGG 545
           VS S+  + ++  G  GGG  G+ SG   +GS                  GGS   G GG
Sbjct: 23  VSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNLGGNKSISISVAAGGSRAGGFGG 82

Query: 546 GGGRGSYGSG-GSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGS 604
           G    ++  G G  +GSG G    GG GGG G  G    +GG+ G  G GG G  GG G 
Sbjct: 83  GRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGG 142

Query: 605 GGGSSGGSIGGRGS--SSGGVKSSGGSSSVKFVSTTYS 640
            GGS  G  GG GS  S GG    G    ++ V+   S
Sbjct: 143 FGGS--GGFGGPGSLGSPGGFGPGGFPGGIQEVTINQS 178



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 59/148 (39%), Positives = 68/148 (45%), Gaps = 24/148 (16%)

Query: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSY--------GSGGGSYG--SGGGGGGGRGSYGS 554
           +S   +  SGGGS+G  G      GSS         G+GGG+YG  SG GG G R  Y  
Sbjct: 1   MSRQASKTSGGGSQGFSGRSAVVSGSSRMSCVAHSGGAGGGAYGFRSGAGGFGSRSLYNL 60

Query: 555 GGS-----SYGSGGGSYGSGGGGGGH----GSYGSGSSSG---GYRGGSGGGGGGSSGGR 602
           GG+     S  +GG   G  GGG       G YG G  SG   G+ GG GGG G   G  
Sbjct: 61  GGNKSISISVAAGGSRAGGFGGGRSSCAFAGGYGGGFGSGYGGGFGGGFGGGRGMGGGFG 120

Query: 603 GSGGGSSGGSIGGRG--SSSGGVKSSGG 628
           G+GG    G  GG G     GG   SGG
Sbjct: 121 GAGGFGGAGGFGGAGGFGGPGGFGGSGG 148



 Score = 81.3 bits (199), Expect = 3e-15
 Identities = 54/130 (41%), Positives = 64/130 (49%), Gaps = 6/130 (4%)

Query: 482 YRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGS 541
           +R+   G  SR       N S+S+S +    +GG   GG GGG  S   + G GGG +GS
Sbjct: 45  FRSGAGGFGSRSLYNLGGNKSISISVA----AGGSRAGGFGGGRSSCAFAGGYGGG-FGS 99

Query: 542 GGGGGGGRGSYGSGGSSYGSGG-GSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSG 600
           G GGG G G  G  G   G GG G +G  GG GG G +G     GG  G  G G  GS G
Sbjct: 100 GYGGGFGGGFGGGRGMGGGFGGAGGFGGAGGFGGAGGFGGPGGFGGSGGFGGPGSLGSPG 159

Query: 601 GRGSGGGSSG 610
           G G GG   G
Sbjct: 160 GFGPGGFPGG 169



 Score = 36.6 bits (83), Expect = 0.074
 Identities = 21/46 (45%), Positives = 23/46 (50%), Gaps = 2/46 (4%)

Query: 583 SSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGG 628
           SS      +GG GGG  G  G GGG  GG   G GS SG  +  GG
Sbjct: 527 SSSTTSASAGGYGGGYGG--GMGGGLGGGFSAGGGSGSGFGRGGGG 570


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  684 bits (1766), Expect = 0.0
 Identities = 391/645 (60%), Positives = 457/645 (70%), Gaps = 67/645 (10%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQ-RRTTSSSTRRSGGGGGRFSSCGGGGGSFGAG 59
           MSRQ  S   +RSGG  S  +A  I     RT+ +S  RSGGGGG     GG G    AG
Sbjct: 1   MSRQ--SSVSFRSGGSRSFSTASAITPSVSRTSFTSVSRSGGGGG-----GGFGRVSLAG 53

Query: 60  ----GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIG 115
               GG+GSRSL NLGGSK ISIS +     G  F   +G G  GG GFGGG   G G G
Sbjct: 54  ACGVGGYGSRSLYNLGGSKRISISTS-----GGSFRNRFGAGAGGGYGFGGGAGSGFGFG 108

Query: 116 GGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQK 175
           GG  GGFG GGG   GGGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+
Sbjct: 109 GGAGGGFGLGGGAGFGGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQR 163

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           V++ EREQIK+LNN+FASFIDKVRFLEQQN+VL TKW LLQ+  T T   NLEP FE +I
Sbjct: 164 VRTEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYI 223

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
           NNLRR++D +  ++ RLDSEL+NMQD+VED++NKYEDEINKRT AENEFV +KKDVD AY
Sbjct: 224 NNLRRQLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAY 283

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           M KV+L+AK+D L  EI+F+   + AELSQMQT +S+T+V+LSMDNNR+LDLDSIIAEVK
Sbjct: 284 MNKVELEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVK 343

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQYE+IA +S+ EAES YQ+KYEELQ TAGRHGD +RN+K EISE+NR+IQRLR+EIDNV
Sbjct: 344 AQYEEIANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNV 403

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           KKQ +NLQ +I+DAEQRGE ALKDA+NKL +LE+ALQ+AK+D+ARLLR+YQELMNTKLAL
Sbjct: 404 KKQCANLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLAL 463

Query: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSG 535
           D+EIATYR LLEGEE R+SGE    V++SV TS  ++S G                    
Sbjct: 464 DVEIATYRKLLEGEECRLSGEGVGPVNISVVTS--SVSSG-------------------- 501

Query: 536 GGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGG 595
              YGSG G GGG G         G  GG  G G  GG  GSY S SS     GG G GG
Sbjct: 502 ---YGSGSGYGGGLG---------GGLGGGLGGGLAGGSSGSYYSSSS-----GGVGLGG 544

Query: 596 GGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYS 640
           G S G  GSG  +S G   G G  SGG    G SSSVKFVSTT S
Sbjct: 545 GLSVG--GSGFSASSGRGLGVGFGSGG----GSSSSVKFVSTTSS 583


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  684 bits (1764), Expect = 0.0
 Identities = 399/659 (60%), Positives = 468/659 (71%), Gaps = 47/659 (7%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           M+RQ   +S      GFS  SA +    R    S   RSGG GG   +CG   G+    G
Sbjct: 1   MNRQVCKKSFSGRSQGFSGRSAVVSGSSRM---SCVARSGGAGG--GACGFRSGA----G 51

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG---GFGG---GGFGGG-- 112
            FGSRSL NLG +KSISISVA G  R  GFGGG    GF GG   GFGG   GGFGGG  
Sbjct: 52  SFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRG 111

Query: 113 -GIGGGGFGGFGSGGGGFGGGG-FGG-GGYGG--GYGPVCPPGGIQEVTINQSLLQPLNV 167
            G G GG GGFG G GGFGG G FGG G +GG  G+GP   PGGIQEV +NQSLLQPLNV
Sbjct: 112 VGSGFGGAGGFG-GAGGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNV 170

Query: 168 EIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNL 227
           EIDP+I +VK++EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKWELLQQ  T +   +L
Sbjct: 171 EIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSL 230

Query: 228 EPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTI 287
           EP FES+I+ L +++D L  ++  L+ ELK+MQD+VED++ KYEDEINKRT AENEFV +
Sbjct: 231 EPCFESYISFLCKQLDSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGL 290

Query: 288 KKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDL 347
           KKDVD A+M KV+LQAK+D+L  E+ FL  LY+ ELSQMQ+  S+T+V+LSMDNNR LDL
Sbjct: 291 KKDVDAAFMNKVELQAKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDL 350

Query: 348 DSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQR 407
            SIIAEV+AQYE+IAQ+SK+EAE+LYQ+K  ELQ TAGRHGD +RN+K EI ELNR+IQR
Sbjct: 351 GSIIAEVRAQYEEIAQRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQR 410

Query: 408 LRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQE 467
           LR+EI+NVKKQ +NLQ +I++AEQRGE ALKDA  KL DL+ ALQ+AK+DLARLLRDYQE
Sbjct: 411 LRAEIENVKKQNANLQTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQE 470

Query: 468 LMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGS 527
           LMN KLALD+EIATYR LLEGEE RMSGEC   V +SV ++ T+ S            GS
Sbjct: 471 LMNVKLALDVEIATYRKLLEGEECRMSGECQSAVCISVVSNVTSTS------------GS 518

Query: 528 GGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587
            GSS G  GG  GSG GG  G GS  S  S YG  GGS GSG GG   GS G   SSG Y
Sbjct: 519 SGSSRGVFGGVSGSGSGGYKG-GSSSSSSSGYGVSGGS-GSGYGGVSSGSTGGRGSSGSY 576

Query: 588 RGGSGG---GGGGSSGGRGSGGGSSGGSI---GGRGSSSGGVKSSGGSSSVKFVSTTYS 640
           +  S G   GG GS     SG GSS GSI   GG G  SGG    GGS+S++F  TT S
Sbjct: 577 QSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGG----GGSTSIRFSQTTSS 631



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 39/111 (35%), Positives = 48/111 (43%), Gaps = 8/111 (7%)

Query: 538 SYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGG----GGHGSYGSGS--SSGGYRGGS 591
           S+     G  GR +  SG S       S G+GGG      G GS+GS S  + G  +  S
Sbjct: 9   SFSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSIS 68

Query: 592 GGGGGGSSGGRGSGGG-SSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTYSG 641
                GSS   G GGG SS G  GG G   GG    GG    + V + + G
Sbjct: 69  ISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGG-SYGGGFGGGRGVGSGFGG 118


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  675 bits (1742), Expect = 0.0
 Identities = 375/599 (62%), Positives = 452/599 (75%), Gaps = 47/599 (7%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSS-------CGGGG 53
           MS QFSS+S       FSS S      +R  ++SS+  SGGG     S       CGGGG
Sbjct: 1   MSHQFSSQSA------FSSMS------RRVYSTSSSAGSGGGSPAVGSVCYARGRCGGGG 48

Query: 54  GSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGG 113
                G GFGSRSL NLGGS+SISI++   G   SGF  G G GGFGGG     GFG G 
Sbjct: 49  YGIH-GRGFGSRSLYNLGGSRSISINLM--GRSTSGFCQGGGVGGFGGGR----GFGVGS 101

Query: 114 IGGGGFGGFGSGGGGFGGGGFGGGGYG-GGYGPVCPPGGIQEVTINQSLLQPLNVEIDPE 172
            G GGFGG     GGFGG GFG   +G GG+GP CPPGGIQEVTINQSLL+PL++E+DPE
Sbjct: 102 TGAGGFGG-----GGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPE 156

Query: 173 IQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFE 232
           IQ++K++EREQI  LNN+FASFIDKVRFLEQQNQVLQTKWELLQQV+TST T+NLEP  E
Sbjct: 157 IQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLE 216

Query: 233 SFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVD 292
           ++I +LRR+VD L ++Q R ++E+++MQD+VEDY++KYEDEINKRT +EN+FV +KKDVD
Sbjct: 217 NYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVD 276

Query: 293 GAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIA 352
            AY++KVDL++++D L  E++FL  L+  ELSQ+QT IS+TNVILSMDNNRSLDLDSII 
Sbjct: 277 AAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIID 336

Query: 353 EVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEI 412
            V+ QYE IAQ+SK EAE+LYQ+KY+ELQITAGRHGD ++NSK+EI+ELNR +QRL++EI
Sbjct: 337 AVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEI 396

Query: 413 DNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTK 472
            NVKKQI  +Q  ISDAE+RGE AL+DA  KL DLE+ALQQ+KE+LARLLRDYQ ++  K
Sbjct: 397 SNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVK 456

Query: 473 LALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSY 532
           L+LD+EIATYR LLEGEESRMSGE   +VS+SV  S  +++GG    GGGG YGSGG  Y
Sbjct: 457 LSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGG---AGGGGSYGSGG--Y 511

Query: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGS 591
           G      GSGGG GGGR SY  GG + G  GG YGSG GGGG GSYG    SG  RG S
Sbjct: 512 GG-----GSGGGYGGGR-SY-RGGGARGRSGGGYGSGCGGGG-GSYGGSGRSG--RGSS 560



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 37/99 (37%), Positives = 45/99 (45%), Gaps = 10/99 (10%)

Query: 551 SYGSGGSSYGSGGGSYGSGG-GGGGHGSYGSGSSS------GGYRGGSGGGGGGSSGG-- 601
           S GSGG S   G   Y  G  GGGG+G +G G  S      GG R  S    G S+ G  
Sbjct: 24  SAGSGGGSPAVGSVCYARGRCGGGGYGIHGRGFGSRSLYNLGGSRSISINLMGRSTSGFC 83

Query: 602 RGSG-GGSSGGSIGGRGSSSGGVKSSGGSSSVKFVSTTY 639
           +G G GG  GG   G GS+  G    GG     F ++ +
Sbjct: 84  QGGGVGGFGGGRGFGVGSTGAGGFGGGGFGGAGFGTSNF 122



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 22/53 (41%), Positives = 25/53 (47%), Gaps = 2/53 (3%)

Query: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSV 632
           S SSS G  GGS   G         GGG  G  I GRG  S  + + GGS S+
Sbjct: 20  STSSSAGSGGGSPAVGSVCYARGRCGGGGYG--IHGRGFGSRSLYNLGGSRSI 70


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  658 bits (1698), Expect = 0.0
 Identities = 370/579 (63%), Positives = 424/579 (73%), Gaps = 32/579 (5%)

Query: 8   RSGYRSGGGFSSGSAGIINYQRRTTSS-STRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
           RS   S  GFS+ SA +    R   SS S  RS G GG   +CGG G        FGSRS
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAG--------FGSRS 60

Query: 67  LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
           L  LGGSK ISI     GG      GGYG    G  GFGG G  G G GGG   GFG GG
Sbjct: 61  LYGLGGSKRISI-----GGGSCAISGGYGSRAGGSYGFGGAG-SGFGFGGGAGIGFGLGG 114

Query: 127 GGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKS 186
           G    GGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+V++ EREQIK+
Sbjct: 115 GAGLAGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKT 169

Query: 187 LNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLK 246
           LNN+FASFIDKVRFLEQQN+VL TKW LLQ+  T T   NLEP FE +INNLRR++D + 
Sbjct: 170 LNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIV 229

Query: 247 SDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLD 306
            ++ RLDSEL+NMQD+VED +NKYEDEINKRT AENEFVT+KKDVD AYM KV+LQAK D
Sbjct: 230 GERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKAD 289

Query: 307 NLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSK 366
            L  EI+FL ALY AELSQMQT IS+T+V+LSMDNNR+LDLDSIIAEVKAQYE+IAQ+S+
Sbjct: 290 TLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSR 349

Query: 367 AEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSI 426
           AEAES YQ+KYEELQITAGRHGD +RN+K EI+E+NR+IQRLRSEID+VKKQ +NLQ +I
Sbjct: 350 AEAESWYQTKYEELQITAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAI 409

Query: 427 SDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLL 486
           +DAEQRGE ALKDAKNKL  LEDALQ+AK+DLARLL++YQELMN KLALD+EIATYR LL
Sbjct: 410 ADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469

Query: 487 EGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYG-SGGSSYGSGGGSYGSGGGG 545
           EGEE R++GE    V++SV  S T  SG G   G G G G  GGSSY     SYGSG G 
Sbjct: 470 EGEECRLNGEGVGQVNISVVQS-TVSSGYGGASGVGSGLGLGGGSSY-----SYGSGLGV 523

Query: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584
           GGG  S     SS  + GG   S GGG     Y + SSS
Sbjct: 524 GGGFSS-----SSGRATGGGLSSVGGGSSTIKYTTTSSS 557



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 53/133 (39%), Positives = 58/133 (43%), Gaps = 8/133 (6%)

Query: 504 SVSTSHTTISGGGSRGGGGGGYG----SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559
           S S+S    S   +R  G    G    S   S GSGG     GG G G R  YG GGS  
Sbjct: 10  SHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69

Query: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619
            S GG  GS    GG+GS   GS   G  G   G GGG+  G G GGG+  G  GG G  
Sbjct: 70  ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA--GLAGGFGGP 125

Query: 620 SGGVKSSGGSSSV 632
              V   GG   V
Sbjct: 126 GFPVCPPGGIQEV 138



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 18/35 (51%), Positives = 22/35 (62%)

Query: 5   FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRS 39
           FSS SG  +GGG SS   G    +  TTSSS+R+S
Sbjct: 527 FSSSSGRATGGGLSSVGGGSSTIKYTTTSSSSRKS 561


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  657 bits (1695), Expect = 0.0
 Identities = 368/579 (63%), Positives = 425/579 (73%), Gaps = 32/579 (5%)

Query: 8   RSGYRSGGGFSSGSAGIINYQRRTTSS-STRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
           RS   S  GFS+ SA +    R   SS S  RS G GG   +CGG G        FGSRS
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAG--------FGSRS 60

Query: 67  LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
           L  LGGSK ISI     GG      GGYG    G  GFGG G  G G GGG   GFG GG
Sbjct: 61  LYGLGGSKRISI-----GGGSCAISGGYGSRAGGSYGFGGAG-SGFGFGGGAGIGFGLGG 114

Query: 127 GGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKS 186
           G    GGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+V++ EREQIK+
Sbjct: 115 GAGLAGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKT 169

Query: 187 LNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLK 246
           LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+  T T   NLEP FE +INNLRR++D + 
Sbjct: 170 LNNKFASFIDKVRFLEQQNKVLETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIV 229

Query: 247 SDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLD 306
            ++ RLDSEL+ MQD+VED++NKYEDEINKRT AENEFVT+KKDVD AYM KV+LQAK D
Sbjct: 230 GERGRLDSELRGMQDLVEDFKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKAD 289

Query: 307 NLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSK 366
            L  EI+FL ALY AELSQMQT IS+T+V+LSMDNNR+LDLDSIIAEVKAQYE+IAQ+S+
Sbjct: 290 TLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSR 349

Query: 367 AEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSI 426
           AEAES YQ+KYEELQ+TAGRHGD +RN+K EI+E+NR+IQRLRSEID+VKKQ +NLQ +I
Sbjct: 350 AEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAI 409

Query: 427 SDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLL 486
           +DAEQRGE ALKDAKNKL  LEDALQ+AK+DLARLL++YQELMN KLALD+EIATYR LL
Sbjct: 410 ADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469

Query: 487 EGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYG-SGGSSYGSGGGSYGSGGGG 545
           EGEE R++GE    V++SV  S T  SG G   G G G G  GGSSY     SYGSG G 
Sbjct: 470 EGEECRLNGEGVGQVNISVVQS-TVSSGYGGASGVGSGLGLGGGSSY-----SYGSGLGV 523

Query: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584
           GGG  S     SS  + GG   S GGG     Y + SSS
Sbjct: 524 GGGFSS-----SSGRAIGGGLSSVGGGSSTIKYTTTSSS 557



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 52/133 (39%), Positives = 58/133 (43%), Gaps = 8/133 (6%)

Query: 504 SVSTSHTTISGGGSR--GGGGGGYGSGGSSYGSGGGSYGS--GGGGGGGRGSYGSGGSSY 559
           S S+S    S   +R  G    G+ S   S   G G  G   GG G G R  YG GGS  
Sbjct: 10  SHSSSRRGFSANSARLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69

Query: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619
            S GG  GS    GG+GS   GS   G  G   G GGG+  G G GGG+  G  GG G  
Sbjct: 70  ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA--GLAGGFGGP 125

Query: 620 SGGVKSSGGSSSV 632
              V   GG   V
Sbjct: 126 GFPVCPPGGIQEV 138



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 5   FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRS 39
           FSS SG   GGG SS   G    +  TTSSS+R+S
Sbjct: 527 FSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKS 561


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  655 bits (1689), Expect = 0.0
 Identities = 369/579 (63%), Positives = 424/579 (73%), Gaps = 32/579 (5%)

Query: 8   RSGYRSGGGFSSGSAGIINYQRRTTSS-STRRSGGGGGRFSSCGGGGGSFGAGGGFGSRS 66
           RS   S  GFS+ SA +    R   SS S  RS G GG   +CGG G        FGSRS
Sbjct: 9   RSHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAG--------FGSRS 60

Query: 67  LVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGG 126
           L  LGGSK ISI     GG      GGYG    G  GFGG G  G G GGG   GFG GG
Sbjct: 61  LYGLGGSKRISI-----GGGSCAISGGYGSRAGGSYGFGGAG-SGFGFGGGAGIGFGLGG 114

Query: 127 GGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKS 186
           G    GGFGG G+     PVCPPGGIQEVT+NQSLL PLN++IDP IQ+V++ EREQIK+
Sbjct: 115 GAGLAGGFGGPGF-----PVCPPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKT 169

Query: 187 LNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLK 246
           LNN+FASFIDKVRFLEQQN+VL TKW LLQ+  T T   NLEP FE +INNLRR++D + 
Sbjct: 170 LNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIV 229

Query: 247 SDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLD 306
            ++ RLDSEL+NMQD+VED +NKYEDEINKRT AENEFVT+KKDVD AYM KV+LQAK D
Sbjct: 230 GERGRLDSELRNMQDLVEDLKNKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKAD 289

Query: 307 NLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSK 366
            L  EI+FL ALY AELSQMQT IS+T+V+LSMDNNR+LDLDSIIAEVKAQYE+IAQ+S+
Sbjct: 290 TLTDEINFLRALYDAELSQMQTHISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSR 349

Query: 367 AEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSI 426
           AEAES YQ+KYEELQ+TAGRHGD +RN+K EI+E+NR+IQRLRSEID+VKKQ ++LQ +I
Sbjct: 350 AEAESWYQTKYEELQVTAGRHGDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAI 409

Query: 427 SDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLL 486
           +DAEQRGE ALKDAKNKL  LEDALQ+AK+DLARLL++YQELMN KLALD+EIATYR LL
Sbjct: 410 ADAEQRGEMALKDAKNKLEGLEDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLL 469

Query: 487 EGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYG-SGGSSYGSGGGSYGSGGGG 545
           EGEE R++GE    V+VSV  S T  SG G   G G G G  GGSSY     SYGSG G 
Sbjct: 470 EGEECRLNGEGVGQVNVSVVQS-TISSGYGGASGVGSGLGLGGGSSY-----SYGSGLGI 523

Query: 546 GGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSS 584
           GGG  S     SS  + GG   S GGG     Y + SSS
Sbjct: 524 GGGFSS-----SSGRAIGGGLSSVGGGSSTIKYTTTSSS 557



 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 53/133 (39%), Positives = 58/133 (43%), Gaps = 8/133 (6%)

Query: 504 SVSTSHTTISGGGSRGGGGGGYG----SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSY 559
           S S+S    S   +R  G    G    S   S GSGG     GG G G R  YG GGS  
Sbjct: 10  SHSSSRRGFSANSARLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKR 69

Query: 560 GSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619
            S GG  GS    GG+GS   GS   G  G   G GGG+  G G GGG+  G  GG G  
Sbjct: 70  ISIGG--GSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGA--GLAGGFGGP 125

Query: 620 SGGVKSSGGSSSV 632
              V   GG   V
Sbjct: 126 GFPVCPPGGIQEV 138



 Score = 33.1 bits (74), Expect = 0.81
 Identities = 18/35 (51%), Positives = 21/35 (60%)

Query: 5   FSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRS 39
           FSS SG   GGG SS   G    +  TTSSS+R+S
Sbjct: 527 FSSSSGRAIGGGLSSVGGGSSTIKYTTTSSSSRKS 561


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  600 bits (1548), Expect = e-171
 Identities = 339/558 (60%), Positives = 412/558 (73%), Gaps = 52/558 (9%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           ++RQ   R G R   GFS GSA I+   +R   SS   SGG G R SS           G
Sbjct: 76  IARQQCVRGGPR---GFSCGSA-IVGGGKRGAFSSVSMSGGAG-RCSS-----------G 119

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
           GFGSRSL NL G+KSIS+SVA G  +G+ FG   G GGFG GGFG              G
Sbjct: 120 GFGSRSLYNLRGNKSISMSVA-GSRQGACFG---GAGGFGTGGFG--------------G 161

Query: 121 GFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSRE 180
           GFG    G GG GF          PVCP GGIQEVTINQSLL PL+VEIDPEIQKV++ E
Sbjct: 162 GFGGSFSGKGGPGF----------PVCPAGGIQEVTINQSLLTPLHVEIDPEIQKVRTEE 211

Query: 181 REQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRR 240
           REQIK LNN+FASFIDKV+FLEQQN+VL+TKW LLQQ  T+T + NLEP FE++++ LR+
Sbjct: 212 REQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRK 271

Query: 241 RVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVD 300
           ++D L +D+ RL SELK MQD VED++ KYE+EINKRT AEN+FV +KKDVD AY+ KV+
Sbjct: 272 QLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDVDAAYLNKVE 331

Query: 301 LQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYED 360
           L+AK+D+L  EI+FL  LY AELSQMQT +S+T+V+LSMDNNR+LDLDSIIAEV+AQYE+
Sbjct: 332 LEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVRAQYEE 391

Query: 361 IAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQIS 420
           IAQ+SKAEAE+LYQ+K ++LQI+  +HGD+++N+K EI+ELNR+IQRLR+EI+N+KKQ  
Sbjct: 392 IAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAEIENIKKQCQ 451

Query: 421 NLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIA 480
            LQ S++DAEQRGENALKDA +K  +LE ALQQAKE+LAR+LR+YQELM+ KLALD+EIA
Sbjct: 452 TLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVKLALDIEIA 511

Query: 481 TYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYG 540
           TYR LLEGEE RMSGEC   VS+SV      +SG  S GG  GG GS GS +G   G +G
Sbjct: 512 TYRKLLEGEEYRMSGECQSAVSISV------VSGSTSTGGISGGLGS-GSGFGLSSG-FG 563

Query: 541 SGGGGGGGRGSYGSGGSS 558
           SG G G G G   SG SS
Sbjct: 564 SGSGSGFGFGGSVSGSSS 581



 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 38/102 (37%), Positives = 47/102 (46%), Gaps = 2/102 (1%)

Query: 533 GSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSG 592
           G  G S GS   GGG RG++ S   S G+G  S G  G    +   G+ S S    G   
Sbjct: 85  GPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQ 144

Query: 593 GGGGGSSGGRGSG--GGSSGGSIGGRGSSSGGVKSSGGSSSV 632
           G   G +GG G+G  GG  GGS  G+G     V  +GG   V
Sbjct: 145 GACFGGAGGFGTGGFGGGFGGSFSGKGGPGFPVCPAGGIQEV 186



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 30/90 (33%), Positives = 36/90 (40%), Gaps = 5/90 (5%)

Query: 510 TTISGGGSRGGGGGGYGSGGSSYGSGGGS-----YGSGGGGGGGRGSYGSGGSSYGSGGG 564
           + I GGG RG       SGG+   S GG      Y   G         GS   +   G G
Sbjct: 93  SAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSRQGACFGGAG 152

Query: 565 SYGSGGGGGGHGSYGSGSSSGGYRGGSGGG 594
            +G+GG GGG G   SG    G+     GG
Sbjct: 153 GFGTGGFGGGFGGSFSGKGGPGFPVCPAGG 182



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/91 (32%), Positives = 34/91 (37%)

Query: 515 GGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG 574
           GG RG   G    GG   G+      SGG G    G +GS       G  S      G  
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143

Query: 575 HGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605
            G+   G+   G  G  GG GG  SG  G G
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 20/54 (37%), Positives = 23/54 (42%), Gaps = 1/54 (1%)

Query: 107 GGFGGGGIGGGGFGGFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQ 159
           G    GGI GG   G G G   GFG G   G G+GG          I   T+N+
Sbjct: 539 GSTSTGGISGGLGSGSGFGLSSGFGSGSGSGFGFGGSVSGSSSSKIISTTTLNK 592



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 30/88 (34%), Positives = 31/88 (35%), Gaps = 31/88 (35%)

Query: 572 GGGHG-SYGSGSSSGGYRGG------SGGGGGGSSGGRGSG------------------- 605
           GG  G S GS    GG RG       SGG G  SSGG GS                    
Sbjct: 84  GGPRGFSCGSAIVGGGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143

Query: 606 -----GGSSGGSIGGRGSSSGGVKSSGG 628
                GG+ G   GG G   GG  S  G
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSGKG 171


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  584 bits (1506), Expect = e-167
 Identities = 337/590 (57%), Positives = 417/590 (70%), Gaps = 62/590 (10%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQR-RTTSSSTRRSGGGGGRFSSCGGGGGSFGAG 59
           MSRQ S      S  GFS+ SA      R R +S S  RS  G G      G G    AG
Sbjct: 1   MSRQSSITFQSGSRRGFSTTSAITPAAGRSRFSSVSVARSAAGSG------GLGRISSAG 54

Query: 60  GGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGF 119
             FGSRSL NLGG+K +SI+     G GS    G+GG      G   G   GGG+     
Sbjct: 55  ASFGSRSLYNLGGAKRVSIN-----GCGSSCRSGFGGRASNRFGVNSGFGYGGGV----- 104

Query: 120 GGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
                 GGGF G  F          PVCPPGGIQEVT+NQSLL PL+++IDP IQ+V++ 
Sbjct: 105 ------GGGFSGPSF----------PVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAE 148

Query: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239
           EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+  + T   NLEP F+S+ + LR
Sbjct: 149 EREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELR 208

Query: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299
           R+++ + +++ RL++EL+NMQD+VED++ +YEDEINKRT AENEFV +KKDVD AYM KV
Sbjct: 209 RQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKV 268

Query: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359
           +L+AK+ +L +EI+F+ +++ AELSQ+QTQ+ +T+V+LSMDNNR+LDLDSIIAEVKAQYE
Sbjct: 269 ELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYE 328

Query: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419
           DIA +S+AEAES YQ+KYEELQ+TAGRHGD +RN+K EISE+NR+IQRLR+EID+VKKQ 
Sbjct: 329 DIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQC 388

Query: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479
           S+LQ +I+DAEQRGE ALKDA+ KL DLE+ALQ+AK+D+ARLLR+YQELMN KLALD+EI
Sbjct: 389 SSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEI 448

Query: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY 539
           ATYR LLEGEE R+SGE    V++SV TS  T+S          GYGSG S    GGG+ 
Sbjct: 449 ATYRKLLEGEECRLSGEGVSPVNISVVTS--TLS---------SGYGSGSS---IGGGNL 494

Query: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGG------HGSYGSGSS 583
           G GG         GSG S   SGG S G+G GG G       G  GSGSS
Sbjct: 495 GLGG---------GSGYSFTTSGGHSLGAGLGGSGFSATSNRGLGGSGSS 535



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 35/96 (36%), Positives = 39/96 (40%), Gaps = 8/96 (8%)

Query: 538 SYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGG 597
           S      G GG G   S G+S+GS   S  + GG       G GSS       SG GG  
Sbjct: 36  SVARSAAGSGGLGRISSAGASFGSR--SLYNLGGAKRVSINGCGSSCR-----SGFGGRA 88

Query: 598 SSG-GRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSV 632
           S+  G  SG G  GG  GG    S  V   GG   V
Sbjct: 89  SNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEV 124


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  583 bits (1503), Expect = e-166
 Identities = 328/562 (58%), Positives = 398/562 (70%), Gaps = 49/562 (8%)

Query: 3   RQFSSRSGYRSGGGFSSGSA-GIINYQRRTTSSS---TRRSGGGGGRFSSCGGGGGSFGA 58
           R   SR  Y + GGFSS SA G    Q RT+ SS   +R SG GGG  + CG G G    
Sbjct: 2   RSSVSRQTYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGG--AHCGPGTG---- 55

Query: 59  GGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGG 118
             GFGSRSL NLGG KSIS+SVA         GG   G   GG GFG   F G G G   
Sbjct: 56  --GFGSRSLYNLGGHKSISVSVA---------GGALLGRALGGFGFGSRAFMGQGAGRQT 104

Query: 119 FGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKS 178
           F                        GP CPPGGIQEVT+NQSLL PL+VEIDPEIQ+V++
Sbjct: 105 F------------------------GPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRT 140

Query: 179 REREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQ--VDTSTRTHNLEPYFESFIN 236
           +EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+   +     +NLEP FE+++ 
Sbjct: 141 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLG 200

Query: 237 NLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYM 296
           ++R  +D+L+S++ RLDSEL+N+QD+VED++NKYEDEINK T AENEFV +KKDVD AYM
Sbjct: 201 SMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYM 260

Query: 297 TKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKA 356
            ++DL  K+  L QEIDFL  LY+ ELSQ+QT +S TNV+LSMDNNR+LDLDSIIAEVKA
Sbjct: 261 GRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKA 320

Query: 357 QYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVK 416
           QYE IAQ+S+AEAE+ YQ+KYEELQ+TAG+HGD++R++K EI+EL R IQRL+ E D  K
Sbjct: 321 QYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAK 380

Query: 417 KQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALD 476
           KQ   LQ +I++AEQRGE ALKDA+ KL DL+ AL QAKEDL RLLRDYQELMN KLALD
Sbjct: 381 KQCQQLQTAIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALD 440

Query: 477 LEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGG 536
           +EIATYR LLE EESRMSGEC   VS+SV+ + TT+ GGG+   GGG   S G S G+  
Sbjct: 441 VEIATYRKLLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGGG--ISLGGSGGATK 498

Query: 537 GSYGSGGGGGGGRGSYGSGGSS 558
           G + +  G    +G   S G+S
Sbjct: 499 GGFSTNVGYSTVKGGPVSAGTS 520



 Score =  426 bits (1094), Expect = e-119
 Identities = 263/580 (45%), Positives = 345/580 (59%), Gaps = 83/580 (14%)

Query: 48  SCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGF--- 104
           S  GG  S  A GG GS++  +       S++V+R  G G G   G G GGFG       
Sbjct: 11  STKGGFSSNSASGGSGSQARTSFS-----SVTVSRSSGSGGGAHCGPGTGGFGSRSLYNL 65

Query: 105 GGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGG-YGPVCPPGGIQEVTINQSLLQ 163
           GG       + GG   G   GG GFG   F G G G   +GP CPPGGIQEVT+NQSLL 
Sbjct: 66  GGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPACPPGGIQEVTVNQSLLT 125

Query: 164 PLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQV--DTS 221
           PL+VEIDPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQN+VL+TKW LLQ+   +  
Sbjct: 126 PLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLG 185

Query: 222 TRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAE 281
              +NLEP FE+++ ++R  +D+L+S++ RLDSEL+N+QD+VED++NKYEDEINK T AE
Sbjct: 186 VTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAE 245

Query: 282 NEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDN 341
           NEFV +KKDVD AYM ++DL  K+  L QEIDFL  LY+ ELSQ+QT +S TNV+LSMDN
Sbjct: 246 NEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDN 305

Query: 342 NRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISEL 401
           NR+LDLDSIIAEVKAQYE IAQ+S+AEAE+ YQ+KYEELQ+TAG+HGD++R++K EI+EL
Sbjct: 306 NRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAEL 365

Query: 402 NRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARL 461
            R IQRL+ E D  KKQ   L                         + A+ +A++     
Sbjct: 366 TRTIQRLQGEADAAKKQCQQL-------------------------QTAIAEAEQRGELA 400

Query: 462 LRDYQELMNTKLALDLEIATYRT------LLEGEESRMSGECAPNVSVSVSTSHTTISGG 515
           L+D Q+ +      DL++A ++       LL   +  M+ + A  + V ++T    +   
Sbjct: 401 LKDAQKKLG-----DLDVALHQAKEDLTRLLRDYQELMNVKLA--LDVEIATYRKLLESE 453

Query: 516 GSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGH 575
            SR  G                                S  S   +G  +   GGG    
Sbjct: 454 ESRMSG-----------------------------ECPSAVSISVTGNSTTVCGGGAA-- 482

Query: 576 GSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGG--SSGGSI 613
            S+G G S GG  G + GG   + G     GG  S+G SI
Sbjct: 483 -SFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVSAGTSI 521



 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 33/104 (31%), Positives = 43/104 (41%), Gaps = 4/104 (3%)

Query: 523 GGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGG--GGGGHGSYGS 580
           GG+ S  +S GSG  +  S       R S   GG+  G G G +GS      GGH S   
Sbjct: 14  GGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGGHKSISV 73

Query: 581 GSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVK 624
             + G   G + GG G   G R   G  +G    G     GG++
Sbjct: 74  SVAGGALLGRALGGFG--FGSRAFMGQGAGRQTFGPACPPGGIQ 115



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 34/92 (36%), Positives = 46/92 (50%), Gaps = 5/92 (5%)

Query: 530 SSYGSGGGSYGSGGGGGGGRGSYGSG--GSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGY 587
           S+ G    +  SGG G   R S+ S     S GSGGG++  G G GG GS  S  + GG+
Sbjct: 11  STKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAH-CGPGTGGFGSR-SLYNLGGH 68

Query: 588 RGGSGGGGGGSSGGRGSGG-GSSGGSIGGRGS 618
           +  S    GG+  GR  GG G    +  G+G+
Sbjct: 69  KSISVSVAGGALLGRALGGFGFGSRAFMGQGA 100



 Score = 39.7 bits (91), Expect = 0.009
 Identities = 31/93 (33%), Positives = 39/93 (41%), Gaps = 5/93 (5%)

Query: 538 SYGSGGGGGGGRGSYGSGG---SSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGG 594
           +Y + GG      S GSG    +S+ S   S  SG GGG H   G G+   G R     G
Sbjct: 9   TYSTKGGFSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAH--CGPGTGGFGSRSLYNLG 66

Query: 595 GGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSG 627
           G  S     +GG   G ++GG G  S      G
Sbjct: 67  GHKSISVSVAGGALLGRALGGFGFGSRAFMGQG 99



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 1/72 (1%)

Query: 558 SYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRG 617
           +Y + GG + S    GG GS    S S      S G GGG+  G G+GG  S       G
Sbjct: 9   TYSTKGG-FSSNSASGGSGSQARTSFSSVTVSRSSGSGGGAHCGPGTGGFGSRSLYNLGG 67

Query: 618 SSSGGVKSSGGS 629
             S  V  +GG+
Sbjct: 68  HKSISVSVAGGA 79



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 3/52 (5%)

Query: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSS--GGVKSSGGS 629
           +G+S+    GG+   GGG S G GSGG + GG     G S+  GG  S+G S
Sbjct: 470 TGNSTTVCGGGAASFGGGISLG-GSGGATKGGFSTNVGYSTVKGGPVSAGTS 520



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 17/39 (43%), Positives = 20/39 (51%)

Query: 593 GGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSS 631
           GGG  S GG  S GGS G + GG  ++ G     GG  S
Sbjct: 478 GGGAASFGGGISLGGSGGATKGGFSTNVGYSTVKGGPVS 516


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  559 bits (1441), Expect = e-159
 Identities = 314/568 (55%), Positives = 398/568 (70%), Gaps = 59/568 (10%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           MSRQF+ +SG  + GGFS  SA +        SSS+ R+GG G                G
Sbjct: 1   MSRQFTYKSGAAAKGGFSGCSAVLSG-----GSSSSYRAGGKG--------------LSG 41

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
           GF SRSL +LGG++SIS +VA G    SG+ GGYG                         
Sbjct: 42  GFSSRSLYSLGGARSISFNVASG----SGWAGGYG------------------------- 72

Query: 121 GFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
            FG G   GF G  FG    G     +CPPGGI +VTIN+SLL PLNVE+DPEIQKV+++
Sbjct: 73  -FGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKVRAQ 131

Query: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239
           EREQIK LNN+FASFIDKVRFLEQQNQVL+TKWELLQQ+D +   +NLEP  E +I+NLR
Sbjct: 132 EREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLR 191

Query: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299
           ++++ L  D+ RLDSEL++++++VEDY+ +YE+EINKRT AENEFV +KKDVD AY +KV
Sbjct: 192 KQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYTSKV 251

Query: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359
           +LQAK+D L  EI F   LY+ E +Q+Q+ IS+T++ILSMDNNR+LDLDSIIAEV+AQYE
Sbjct: 252 ELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRAQYE 311

Query: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419
           +IA+KSKAEAE+LYQ+K++ELQ+ AGRHGD ++++K EISEL R+IQRLRSEI++VKKQ 
Sbjct: 312 EIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVKKQC 371

Query: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479
           +NL+ +I+DAEQRG+ ALKDA+ KL++LE ALQQAKE+LAR+LR+YQEL++ KL+LD+EI
Sbjct: 372 ANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLDIEI 431

Query: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGG---GGGYG------SGGS 530
           ATYR LLEGEE RMSGE   +VS+SV  S      G   G G    G YG      SGG 
Sbjct: 432 ATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVSGGY 491

Query: 531 SYGSGGGSYGSGGGGGGGRGSYGSGGSS 558
           S   GG   GSG     G      G +S
Sbjct: 492 SMLPGGCVTGSGNCSPRGEARTRLGSAS 519



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 32/99 (32%), Positives = 41/99 (41%), Gaps = 6/99 (6%)

Query: 531 SYGSGGGSYGSGGG-----GGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSG 585
           +Y SG  + G   G      GG   SY +GG     G  S      GG      + +S  
Sbjct: 6   TYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGS 65

Query: 586 GYRGGSGGGGGGSSGGRGSGGGSSG-GSIGGRGSSSGGV 623
           G+ GG G G G +SG  GS  GS   GS+       GG+
Sbjct: 66  GWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGI 104



 Score = 38.5 bits (88), Expect = 0.019
 Identities = 37/92 (40%), Positives = 41/92 (44%), Gaps = 9/92 (9%)

Query: 538 SYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGG 597
           +Y SG    GG     SG S+  SGG S  S    GG G  G  SS   Y   S GG   
Sbjct: 6   TYKSGAAAKGGF----SGCSAVLSGGSS--SSYRAGGKGLSGGFSSRSLY---SLGGARS 56

Query: 598 SSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGS 629
            S    SG G +GG   GRG +SG   S  GS
Sbjct: 57  ISFNVASGSGWAGGYGFGRGRASGFAGSMFGS 88



 Score = 38.1 bits (87), Expect = 0.025
 Identities = 35/104 (33%), Positives = 42/104 (40%), Gaps = 15/104 (14%)

Query: 505 VSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG 564
           +S   T  SG  ++GG      SG S+  SGG S     GG G  G + S  S Y  GG 
Sbjct: 1   MSRQFTYKSGAAAKGGF-----SGCSAVLSGGSSSSYRAGGKGLSGGFSSR-SLYSLGGA 54

Query: 565 ---SYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605
              S+    G G  G YG G      RG + G  G   G    G
Sbjct: 55  RSISFNVASGSGWAGGYGFG------RGRASGFAGSMFGSVALG 92



 Score = 33.5 bits (75), Expect = 0.62
 Identities = 24/66 (36%), Positives = 34/66 (51%), Gaps = 6/66 (9%)

Query: 577 SYGSGSSS-GGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFV 635
           +Y SG+++ GG+ G S    GGSS    +GG    G     G SS  + S GG+ S+ F 
Sbjct: 6   TYKSGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSG-----GFSSRSLYSLGGARSISFN 60

Query: 636 STTYSG 641
             + SG
Sbjct: 61  VASGSG 66


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  555 bits (1431), Expect = e-158
 Identities = 313/568 (55%), Positives = 398/568 (70%), Gaps = 63/568 (11%)

Query: 1   MSRQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGG 60
           MSRQF+ +SG  + GGFS  SA +              SGG    F +     GS G  G
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVL--------------SGGSSSSFRA-----GSKGLSG 41

Query: 61  GFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFG 120
           GFGSRSL +LGG +S++  VA G G+          GG+                     
Sbjct: 42  GFGSRSLYSLGGVRSLN--VASGSGKS---------GGY--------------------- 69

Query: 121 GFGSG-GGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
           GFG G   GF G  FG    G     VCPPGGI +VT+N+SLL PLNVE+DPEIQKV+++
Sbjct: 70  GFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQKVRAQ 129

Query: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239
           EREQIK+LNN+FASFIDKVRFLEQQNQVL+TKWELLQQ+D +   +NLEP  E +I+NLR
Sbjct: 130 EREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYISNLR 189

Query: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299
           ++++ L  D+ RLDSEL+N++D+VEDY+ +YE+EINKRT AENEFV +KKDVD AY  KV
Sbjct: 190 KQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAYANKV 249

Query: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359
           +LQAK++++ QEI F   L++AE++Q+Q+ IS+ +VILSMDNNR+LDLDSII EV+ QYE
Sbjct: 250 ELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVRTQYE 309

Query: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419
           +IA KSKAEAE+LYQ+K++ELQ+ AGRHGD ++N+K EISEL R+IQR+RSEI+NVKKQ 
Sbjct: 310 EIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENVKKQA 369

Query: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479
           SNL+ +I+DAEQRG+NALKDA+ KL++LE AL QAKE+LAR+LR+YQELM+ KLALD+EI
Sbjct: 370 SNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLALDMEI 429

Query: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGG-----GGGGYGSGGSSYGS 534
           ATYR LLE EE RMSGE    VS+S+ +S    + GGS  G       GGY +  S+  S
Sbjct: 430 ATYRKLLESEECRMSGEFPSPVSISIISS----TSGGSVYGFRPSMVSGGYVANSSNCIS 485

Query: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
           G  S    GG G  RGS      + G G
Sbjct: 486 GVCSV--RGGEGRSRGSANDYKDTLGKG 511



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 29/71 (40%), Positives = 32/71 (45%), Gaps = 4/71 (5%)

Query: 544 GGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG 603
           GG  G  +  SGGSS     GS G  GG G    Y    S GG R  +   G G SGG G
Sbjct: 15  GGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLY----SLGGVRSLNVASGSGKSGGYG 70

Query: 604 SGGGSSGGSIG 614
            G G + G  G
Sbjct: 71  FGRGRASGFAG 81



 Score = 37.7 bits (86), Expect = 0.033
 Identities = 35/103 (33%), Positives = 39/103 (37%), Gaps = 15/103 (14%)

Query: 505 VSTSHTTISGGGSRGGGGGGYG--SGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
           +S   T  SG  ++GG  G     SGGSS     GS G  GG G  R  Y  GG      
Sbjct: 1   MSRQFTCKSGAAAKGGFSGCSAVLSGGSSSSFRAGSKGLSGGFGS-RSLYSLGGVR---- 55

Query: 563 GGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSG 605
             S     G G  G YG G      RG + G  G   G    G
Sbjct: 56  --SLNVASGSGKSGGYGFG------RGRASGFAGSMFGSVALG 90



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 32/81 (39%), Positives = 37/81 (45%), Gaps = 12/81 (14%)

Query: 570 GGGGGHGSYGSGSSSGGYRGGSGG-GGGGSS------GG-----RGSGGGSSGGSIGGRG 617
           GG  G  +  SG SS  +R GS G  GG  S      GG       SG G SGG   GRG
Sbjct: 15  GGFSGCSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGKSGGYGFGRG 74

Query: 618 SSSGGVKSSGGSSSVKFVSTT 638
            +SG   S  GS ++  V  T
Sbjct: 75  RASGFAGSMFGSVALGPVCPT 95


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  536 bits (1381), Expect = e-152
 Identities = 289/506 (57%), Positives = 363/506 (71%), Gaps = 31/506 (6%)

Query: 43  GGRFSSCGGGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGG 102
           G   S C  G G   AG GFGSRSL +LGG++ IS +VA GG R  G+G           
Sbjct: 29  GSLASYCAAGRG---AGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGFR--------- 76

Query: 103 GFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLL 162
              G G+GGG               GF G  FG    G     VCPPGGI +VT+N+SLL
Sbjct: 77  --PGSGYGGGR------------ASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLL 122

Query: 163 QPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTST 222
            PLNVE+DPEIQKV+++EREQIK LN++FASFIDKVRFLEQQNQVL+TKWELLQQ+D + 
Sbjct: 123 APLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNN 182

Query: 223 RTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAEN 282
              NLEP  E +I+NLR++++ L  D+ RLDSEL++M+D+VEDY+ +YE EIN+RT AEN
Sbjct: 183 CKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAEN 242

Query: 283 EFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNN 342
           EFV +KKD D AY  KV+LQAK+D+L +EI FL  LY AE++Q+QT  SET+VILSMDNN
Sbjct: 243 EFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNN 302

Query: 343 RSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELN 402
           R LDLDSIIAEV+  YE+IA KSKAEAE+LYQ+K +ELQ+ A RHGD +++++ E+ ELN
Sbjct: 303 RDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELN 362

Query: 403 RVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLL 462
           R+IQR+R EI NVKKQ ++L+ +I+DAEQRG+NALKDA+ KL++LE AL QAKE+LAR+L
Sbjct: 363 RLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARML 422

Query: 463 RDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTS-----HTTISGGGS 517
           R+YQELM+ KLALD+EIATYR LLEGEE RMSGE   +VS+SV +S     H   S G  
Sbjct: 423 REYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVD 482

Query: 518 RGGGGGGYGSGGSSYGSGGGSYGSGG 543
            G       SG +  G    +   GG
Sbjct: 483 LGASAVAGSSGSTQSGQTKTTEARGG 508



 Score = 40.4 bits (93), Expect = 0.005
 Identities = 30/75 (40%), Positives = 34/75 (45%), Gaps = 10/75 (13%)

Query: 537 GSYGSGGGGGGGRGSYGSGGSSYGSGGG---SYGSGGGGGGHGSYGSGSSSGGYRGGSGG 593
           GS  S    G G G+     S Y  GG    S+   GGG   G YG       +R GSG 
Sbjct: 29  GSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYG-------FRPGSGY 81

Query: 594 GGGGSSGGRGSGGGS 608
           GGG +SG  GS  GS
Sbjct: 82  GGGRASGFAGSMFGS 96



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 27/65 (41%), Positives = 28/65 (43%), Gaps = 7/65 (10%)

Query: 520 GGGGGYGSGGSSYGSGGGSYGSGGGGGGG--RGSYG-SGGSSYGSGGGSYGSGGGGGGHG 576
           G G G+GS  S Y  GG    S    GGG   G YG   GS YG G  S   G  G   G
Sbjct: 40  GAGAGFGSR-SLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRAS---GFAGSMFG 95

Query: 577 SYGSG 581
           S   G
Sbjct: 96  SVALG 100



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 28/62 (45%), Positives = 31/62 (50%), Gaps = 7/62 (11%)

Query: 565 SYGSGGGGGGHGSYGSGS--SSGGYRGGSGG--GGGGSSGGRGSGGGSSGGSIGGRGSSS 620
           SY + G G G G +GS S  S GG R  S    GGG  +GG G   GS  G  GGR S  
Sbjct: 33  SYCAAGRGAGAG-FGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYG--GGRASGF 89

Query: 621 GG 622
            G
Sbjct: 90  AG 91


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  524 bits (1350), Expect = e-149
 Identities = 289/523 (55%), Positives = 368/523 (70%), Gaps = 62/523 (11%)

Query: 46  FSSCG----GGGGSFGAG--------GGFGSRSLVNLGGSKSISISVA--RGGGRGSGFG 91
           FS C     GG GS  A           FGS+SL  LGGS+S+++S A  RGGGR     
Sbjct: 16  FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRL---- 71

Query: 92  GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151
                                              GGF G  FG  G G     VCPPGG
Sbjct: 72  -----------------------------------GGFVGTAFGSAGLGPKCPSVCPPGG 96

Query: 152 IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK 211
           I +VT+N+SLL PLNVE+DPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQNQVL+TK
Sbjct: 97  IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETK 156

Query: 212 WELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYE 271
           W LLQQ+D +    NLEP +E +I+NL+++++ L  D  RLDSEL+NMQD+VEDY+ +YE
Sbjct: 157 WNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 272 DEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 331
            EIN+RT AENEFV +KKDVD AYM KV+LQAK+D+L  EI F   LY+ E++Q+Q+ IS
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 332 ETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSV 391
           +T+++LSMDNNR LDLDSIIAEV+AQYE+IA KSKAEAE+LYQ+K +ELQ+TAG+HGD +
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336

Query: 392 RNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDAL 451
           + +K EISELNR+IQR+RSEI NVKKQ ++L+ +I+DAEQRG+ ALKDA+ KL++LE AL
Sbjct: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396

Query: 452 QQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTT 511
            QAKE+LAR+LR+YQEL++ KLALD+EIATYR LLE EE RMSGE   +VS+SV +S   
Sbjct: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISS--- 453

Query: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554
                + G GG G+  G  +  S   SY +       +GS GS
Sbjct: 454 ----TNAGAGGAGFSMGFGA--SSSYSYKTAAADVKTKGSCGS 490


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  524 bits (1350), Expect = e-149
 Identities = 289/523 (55%), Positives = 368/523 (70%), Gaps = 62/523 (11%)

Query: 46  FSSCG----GGGGSFGAG--------GGFGSRSLVNLGGSKSISISVA--RGGGRGSGFG 91
           FS C     GG GS  A           FGS+SL  LGGS+S+++S A  RGGGR     
Sbjct: 16  FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRL---- 71

Query: 92  GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151
                                              GGF G  FG  G G     VCPPGG
Sbjct: 72  -----------------------------------GGFVGTAFGSAGLGPKCPSVCPPGG 96

Query: 152 IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK 211
           I +VT+N+SLL PLNVE+DPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQNQVL+TK
Sbjct: 97  IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETK 156

Query: 212 WELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYE 271
           W LLQQ+D +    NLEP +E +I+NL+++++ L  D  RLDSEL+NMQD+VEDY+ +YE
Sbjct: 157 WNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 272 DEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 331
            EIN+RT AENEFV +KKDVD AYM KV+LQAK+D+L  EI F   LY+ E++Q+Q+ IS
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 332 ETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSV 391
           +T+++LSMDNNR LDLDSIIAEV+AQYE+IA KSKAEAE+LYQ+K +ELQ+TAG+HGD +
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDL 336

Query: 392 RNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDAL 451
           + +K EISELNR+IQR+RSEI NVKKQ ++L+ +I+DAEQRG+ ALKDA+ KL++LE AL
Sbjct: 337 KLTKAEISELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGAL 396

Query: 452 QQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTT 511
            QAKE+LAR+LR+YQEL++ KLALD+EIATYR LLE EE RMSGE   +VS+SV +S   
Sbjct: 397 HQAKEELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISS--- 453

Query: 512 ISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554
                + G GG G+  G  +  S   SY +       +GS GS
Sbjct: 454 ----TNAGAGGAGFSMGFGA--SSSYSYKTAAADVKTKGSCGS 490


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  473 bits (1218), Expect = e-133
 Identities = 248/408 (60%), Positives = 320/408 (78%), Gaps = 7/408 (1%)

Query: 137 GGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFID 196
           GG GGGYG     GGI  VT+NQSLL PL +E+DP IQ V+++E+EQIK+LNN+FASFID
Sbjct: 48  GGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFID 107

Query: 197 KVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSEL 256
           KVRFLEQQN++L+TKW LLQQ  T+    N++  FES+INNLRR+++ L  ++ +L++EL
Sbjct: 108 KVRFLEQQNKMLETKWSLLQQQKTARS--NMDNMFESYINNLRRQLETLGQEKLKLEAEL 165

Query: 257 KNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLT 316
            NMQ +VED++NKYEDEINKRT  ENEFV IKKDVD AYM KV+L+++L+ L  EI+FL 
Sbjct: 166 GNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLR 225

Query: 317 ALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSK 376
            LY+ E+ ++Q+QIS+T+V+LSMDN+RSLD+DSIIAEVKAQYEDIA +S+AEAES+YQ K
Sbjct: 226 QLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIK 285

Query: 377 YEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENA 436
           YEELQ  AG+HGD +R +K EISE+NR I RL++EI+ +K Q ++L+ +I+DAEQRGE A
Sbjct: 286 YEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELA 345

Query: 437 LKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGE 496
           +KDA  KL++LE ALQ+AK+D+AR LR+YQELMN KLALD+EIATYR LLEGEESR+   
Sbjct: 346 IKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESG 405

Query: 497 CAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGG 544
              N+S+    + TT    G      GG  S G SY S G S+GSG G
Sbjct: 406 -MQNMSIH---TKTTSGYAGGLSSAYGGLTSPGLSY-SLGSSFGSGAG 448



 Score = 33.9 bits (76), Expect = 0.48
 Identities = 19/39 (48%), Positives = 21/39 (53%)

Query: 565 SYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRG 603
           SY SG G     S  S   S  +RGG GGG GG+SG  G
Sbjct: 24  SYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGG 62



 Score = 31.2 bits (69), Expect = 3.1
 Identities = 21/62 (33%), Positives = 27/62 (43%), Gaps = 6/62 (9%)

Query: 501 VSVSVSTSHTTISGGGSRGGGGGGYGSG------GSSYGSGGGSYGSGGGGGGGRGSYGS 554
           +S+ V+     +S  G R      Y SG       SS+   G S   GG GGG  G+ G 
Sbjct: 1   MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM 60

Query: 555 GG 556
           GG
Sbjct: 61  GG 62



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 26/71 (36%), Positives = 30/71 (42%), Gaps = 17/71 (23%)

Query: 3  RQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGF 62
          R FSSRS Y SG G             R +SSS  R G    R    GG GG +G   G 
Sbjct: 18 RAFSSRS-YTSGPG------------SRISSSSFSRVGSSNFR----GGLGGGYGGASGM 60

Query: 63 GSRSLVNLGGS 73
          G  + V +  S
Sbjct: 61 GGITAVTVNQS 71



 Score = 29.6 bits (65), Expect = 9.0
 Identities = 24/56 (42%), Positives = 29/56 (51%), Gaps = 3/56 (5%)

Query: 583 SSGGYRGG-SGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVST 637
           ++ GY GG S   GG +S G     GSS GS  G GSSS    SS  +  VK + T
Sbjct: 415 TTSGYAGGLSSAYGGLTSPGLSYSLGSSFGS--GAGSSSFSRTSSSRAVVVKKIET 468


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  472 bits (1214), Expect = e-133
 Identities = 304/655 (46%), Positives = 392/655 (59%), Gaps = 72/655 (10%)

Query: 3   RQFSSRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSCGGGGGSFGAGGGF 62
           R +   SG+R G  FSS SA       R  ++S            SC  G G  G G  F
Sbjct: 4   RSYRVSSGHRVGN-FSSCSAMTPQNLNRFRANSV-----------SCWSGPGFRGLGS-F 50

Query: 63  GSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGF 122
           GSRS++  G   S S  +A  G R    G  +G G   G GFG G   G G       G 
Sbjct: 51  GSRSVITFG---SYSPRIAAVGSRPIHCGVRFGAGC--GMGFGDGRGVGLGPRADSCVGL 105

Query: 123 GSGGGGFGGGGFGGGGYG---GGYGPVCPPGGIQEVTINQSLLQPLNVEIDPEIQKVKSR 179
           G G G   G GFGG G+G   GG G    P  I  VT+N+SLL PLN+EIDP  Q+VK  
Sbjct: 106 GFGAGSGIGYGFGGPGFGYRVGGVGVPAAPS-ITAVTVNKSLLTPLNLEIDPNAQRVKKD 164

Query: 180 EREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLR 239
           E+EQIK+LNN+FASFIDKVRFLEQQN++L+TKW  LQ+        NLEP FES+I NLR
Sbjct: 165 EKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQE--QKCIRSNLEPLFESYITNLR 222

Query: 240 RRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKV 299
           R+++ L SDQ+RL +E  ++QD++E ++ KYE+E+  R NAENEFV +KKDVD A+M K 
Sbjct: 223 RQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVALKKDVDAAFMNKS 282

Query: 300 DLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYE 359
           DL+A +D L QEIDFL  LY  E+  +Q+ ISET+VI+ MDN+R L+LD IIAEVKAQYE
Sbjct: 283 DLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNLDGIIAEVKAQYE 342

Query: 360 DIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQI 419
           ++A++S+A+AE+ YQ+KYEE+Q+TAG+H D++RN + EI+EL R+IQRL++EI++ K Q 
Sbjct: 343 EVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQRLKAEIEHAKAQR 402

Query: 420 SNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEI 479
           + L+ ++++AEQ+GE  L DAK KL DLE ALQQAK+D+AR L +YQELMN KL LD+EI
Sbjct: 403 AKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQELMNAKLGLDIEI 462

Query: 480 ATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSY 539
           ATYR LLEGEESR+     P V++SVS+S   +  G      G     GG ++       
Sbjct: 463 ATYRRLLEGEESRLCEGVGP-VNISVSSSRGGLVCGPEPLVAGSTLSRGGVTF------- 514

Query: 540 GSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSS 599
                         SG SS  +  G   S            G S GG R     G   S+
Sbjct: 515 --------------SGSSSVCATSGVLAS-----------CGPSLGGARVAPATGDLLST 549

Query: 600 GGRGSGGGSSGGSI----------GGRGSSSGGVKSSGGSSSVKFVSTTYSGVTR 644
           G R      S   +          GG  S SGG      SSSV+FVSTT S  T+
Sbjct: 550 GTRSGSMLISEACVPSVPCPLPTQGGFSSCSGG-----RSSSVRFVSTTTSCRTK 599


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  463 bits (1192), Expect = e-130
 Identities = 251/478 (52%), Positives = 344/478 (71%), Gaps = 11/478 (2%)

Query: 98  GFGGGGFGG-GGFGGGGIGGGGFGGFGSGGGGFGGGGFGG---GGYGGGYG-PVCPPGGI 152
           G   GGF   GGF    +   G    GS G  +G GG  G   G + GG G  +CPPGGI
Sbjct: 24  GRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCPPGGI 83

Query: 153 QEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKW 212
           QEVTINQ+LL PL +EIDP+ Q V+++E ++I++LNNQFASFIDKVRFLEQQN+VL+TKW
Sbjct: 84  QEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKW 143

Query: 213 ELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYED 272
            LLQQ   S     LEP FE+ ++ LR++++QL+ ++  LD+ELK  +D  E+Y++KYE+
Sbjct: 144 HLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEE 203

Query: 273 EINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISE 332
           E ++R   EN+FV +KKDVDG +++K++L+ KL+ L++ + FL  L + EL Q+QTQ S+
Sbjct: 204 EAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASD 263

Query: 333 TNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVR 392
           T+V+LSMDNNR LD  SII EV+A+YE+IA+ SKAEAE+LYQ+KY+ELQ++A  HGD ++
Sbjct: 264 TSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQ 323

Query: 393 NSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQ 452
            +K++IS+L++ IQRL+S+ +N+KKQ ++LQ +I+DAEQRGE ALKDA+ K+++LE AL+
Sbjct: 324 ETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALR 383

Query: 453 QAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTI 512
            AK++LARLL +YQEL +TKL+LD+EIATYR LLEGEE RMSGEC   V++S S   + +
Sbjct: 384 MAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTIS-SVGGSAV 442

Query: 513 SGGGSRGGGGG--GYGSGGSSYGSGGGSYGSGGGG---GGGRGSYGSGGSSYGSGGGS 565
             GG  GG G   G GSG  S GS   S  +GG     G G+       S  GS  GS
Sbjct: 443 MSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSSAGS 500



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 497 CAPNVSVSVSTSHTTISGGGSRGG--GGGGYGS------GGSSYGSGGGSYGSGGGGGGG 548
           C      S  ++ +  S G SRGG    GG+ S      GG   GS G ++GSGG  G  
Sbjct: 6   CRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVR 65

Query: 549 RGSYGSG-GSSYGSGGG 564
            G +  G G S    GG
Sbjct: 66  FGEWSGGPGLSLCPPGG 82



 Score = 30.8 bits (68), Expect = 4.0
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 7  SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGG-GGRFSSCGGGGG 54
          SR G+ S GGFSS S          +  ST  SGG  G RF    GG G
Sbjct: 26 SRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPG 74



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 24/55 (43%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKF 634
           S  S G  RGG    GG SS    S GG   GS   RGS+ G    SGG   V+F
Sbjct: 19  SARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGS---RGSTWG----SGGRLGVRF 66


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  452 bits (1164), Expect = e-127
 Identities = 243/435 (55%), Positives = 322/435 (74%), Gaps = 16/435 (3%)

Query: 112 GGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDP 171
           GG+G     G G+              YGG  G      GI+EVTINQSLL PL ++ DP
Sbjct: 32  GGLGSSSLYGLGASRPRVAVRS----AYGGPVG-----AGIREVTINQSLLAPLRLDADP 82

Query: 172 EIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYF 231
            +Q+V+  E EQIK+LNN+FASFIDKVRFLEQQN++L+TKW LLQ+   S ++  L   F
Sbjct: 83  SLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQE-QKSAKSSRLPDIF 141

Query: 232 ESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDV 291
           E+ I  LR +++ L+ D  RL++EL++MQD+VED++NKYEDEIN RT AENEFV +KKDV
Sbjct: 142 EAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDV 201

Query: 292 DGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSII 351
           D AYM+KV+L+AK+D L  EI+FL  L + EL+++Q+QIS+T+V+LSMDN+RSLDLD II
Sbjct: 202 DAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGII 261

Query: 352 AEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSE 411
           AEVKAQYE++A+ S+AEAE+ YQ+K+E LQ  AG+HGD +RN++ EISE+NR IQRL++E
Sbjct: 262 AEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAE 321

Query: 412 IDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNT 471
           IDN+K Q + L+ +I++AE+RGE ALKDA+ K  +LE ALQ+ K+D+AR LR+YQELM+ 
Sbjct: 322 IDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSV 381

Query: 472 KLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSS 531
           KLALD+EIATYR LLEGEESR++G+    V++SV       S GGS  GGG G   GG +
Sbjct: 382 KLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMN-----STGGSSSGGGIGLTLGG-T 435

Query: 532 YGSGGGSYGSGGGGG 546
            GS   S+ S  G G
Sbjct: 436 MGSNALSFSSSAGPG 450


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  411 bits (1057), Expect = e-115
 Identities = 249/527 (47%), Positives = 322/527 (61%), Gaps = 112/527 (21%)

Query: 46  FSSCG----GGGGSFGAG--------GGFGSRSLVNLGGSKSISISVA--RGGGRGSGFG 91
           FS C     GG GS  A           FGS+SL  LGGS+S+++S A  RGGGR     
Sbjct: 16  FSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLSCLGGSRSLALSAAARRGGGRL---- 71

Query: 92  GGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGG 151
                                              GGF G  FG  G G     VCPPGG
Sbjct: 72  -----------------------------------GGFVGTAFGSAGLGPKCPSVCPPGG 96

Query: 152 IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTK 211
           I +VT+N+SLL PLNVE+DPEIQ+V+++EREQIK+LNN+FASFIDKVRFLEQQNQVL+TK
Sbjct: 97  IPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETK 156

Query: 212 WELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYE 271
           W LLQQ+D +    NLEP +E +I+NL+++++ L  D  RLDSEL+NMQD+VEDY+ +YE
Sbjct: 157 WNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYE 216

Query: 272 DEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQIS 331
            EIN+RT AENEFV +KKDVD AYM KV+LQAK+D+L  EI F   LY+ E++Q+Q+ IS
Sbjct: 217 VEINRRTAAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHIS 276

Query: 332 ETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQIT---AGRHG 388
           +T+++LSMDNNR LDLDSIIAEV+AQYE+IA KSKAEAE+LYQ+K  +L+     A + G
Sbjct: 277 DTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRG 336

Query: 389 D-SVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDL 447
           D ++++++ ++ EL                                E AL  AK      
Sbjct: 337 DCALKDARAKLDEL--------------------------------EGALHQAK------ 358

Query: 448 EDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVST 507
                   E+LAR+LR+YQEL++ KLALD+EIATYR LLE EE RMSGE   +VS+SV +
Sbjct: 359 --------EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVIS 410

Query: 508 SHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGS 554
           S        + G GG G+  G  +  S   SY +       +GS GS
Sbjct: 411 S-------TNAGAGGAGFSMGFGA--SSSYSYKTAAADVKTKGSCGS 448


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  407 bits (1045), Expect = e-113
 Identities = 238/472 (50%), Positives = 313/472 (66%), Gaps = 28/472 (5%)

Query: 111 GGGIGGGGFGGFGSGG---GGFG--------GGGFGGGGYGGGYGPVCPPGG-IQEVTIN 158
           GGG G    G  GS      GFG        GG   G GY    G  C P   I  VTIN
Sbjct: 41  GGGRGLRALGCLGSRSLCNVGFGRPRVASRCGGTLPGFGYR--LGATCGPSACITPVTIN 98

Query: 159 QSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQV 218
           +SLL PL +EIDP +Q+VK  E+EQIK LNN+FASFI+KVRFLEQ+N++L+TKW  +QQ 
Sbjct: 99  ESLLVPLALEIDPTVQRVKRDEKEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQ 158

Query: 219 DTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRT 278
                  N+EP FE +I+ LRR++D +  D+ RL+SEL ++Q  +E Y+ KYE+E++ R 
Sbjct: 159 RCCQT--NIEPIFEGYISALRRQLDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRP 216

Query: 279 NAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILS 338
             ENEFV +KKDVD A++ K DL+   + L QEIDFL +LY+ E+  +Q+QISET+VI+ 
Sbjct: 217 CVENEFVALKKDVDTAFLMKADLETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVK 276

Query: 339 MDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEI 398
           MDN+R LD+D IIAE+KAQY+DIA +SKAEAE+ YQ +YEEL++TAG H D++RN K EI
Sbjct: 277 MDNSRELDVDGIIAEIKAQYDDIASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEI 336

Query: 399 SELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDL 458
            E+N++IQRL+ E +NVK Q   L+ +I++AEQ+GE AL DAK KL  LE+ALQ+AK+D+
Sbjct: 337 LEMNKLIQRLQQETENVKAQRCKLEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDM 396

Query: 459 ARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAP-NVSVSVS----------T 507
           A LL++YQE+MN+KL LD+EIATYR LLEGEE R+     P N+SVS S           
Sbjct: 397 ACLLKEYQEVMNSKLGLDIEIATYRRLLEGEEHRLCEGIGPVNISVSSSKGAFLYEPCGV 456

Query: 508 SHTTISGGGSRGGGGGG-YGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSS 558
           S   +S G  R  GG    G+G            S G G     + G+GGSS
Sbjct: 457 STPVLSTGVLRSNGGCSIVGTGELYVPCEPQGLLSCGSGRKSSMTLGAGGSS 508


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  401 bits (1030), Expect = e-111
 Identities = 237/502 (47%), Positives = 322/502 (64%), Gaps = 36/502 (7%)

Query: 96  GGGFGGGGFG---------------GGGFGGGGIGGGGFGGFGSGG--GGFGGGGFGGGG 138
           G GFGG  F                   + G     G  GGFGS    GGF  G  G   
Sbjct: 4   GSGFGGRAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGRS- 62

Query: 139 YGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFID 196
           +G   G VC P    I  V++N+SLL PLN+EIDP  Q VK  E+EQIKSLN++FA+FID
Sbjct: 63  FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 197 KVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSEL 256
           KVRFLEQQN++L+TK +  Q  +      NLEP FE +I  LRR  + +++D  RL SEL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 257 KNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLT 316
            ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY+ K DL+A ++ L QEIDFL 
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 317 ALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSK 376
            LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+KAQY+DI  +S+AEAES Y+SK
Sbjct: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 377 YEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENA 436
            EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N K Q S L+ +++ +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 437 LKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRM-SG 495
           L DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL LD+EIATYR LLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 496 ECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGSGGGSYGSG------------G 543
             A NV VS S+    + G     G     GS  S+  +G  +  +G            G
Sbjct: 421 IGAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCG 479

Query: 544 GGGGGRGSYGSGGSSYGSGGGS 565
           GG  G GS G      GS G S
Sbjct: 480 GGSCGVGSCGISSLGVGSCGSS 501


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  397 bits (1019), Expect = e-110
 Identities = 212/410 (51%), Positives = 292/410 (71%), Gaps = 9/410 (2%)

Query: 113 GIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG----PVCPPGG--IQEVTINQSLLQPLN 166
           G G       GS G     GGF  G  G  +G     VC P    I  V++N+SLL PLN
Sbjct: 50  GFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLN 109

Query: 167 VEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHN 226
           +EIDP  Q VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TKW+  Q  +      N
Sbjct: 110 LEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQ--NQRCCESN 167

Query: 227 LEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVT 286
           LEP F  +I  LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E+  R  AENEFV 
Sbjct: 168 LEPLFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVV 227

Query: 287 IKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLD 346
           +KKDVD AY+ K DL+A ++ L +E  FL  LY+ E+  +Q  IS+T+VI+ MDN+R L+
Sbjct: 228 LKKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLN 287

Query: 347 LDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQ 406
           +D IIAE+KAQY+D+A +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQ
Sbjct: 288 MDCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQ 347

Query: 407 RLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQ 466
           RL +EI+N K Q + L+ ++++AEQ+GE AL DA+ KL +LE ALQ+AK+D+A LL++YQ
Sbjct: 348 RLTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQ 407

Query: 467 ELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGG 516
           E+MN+KL LD+EIATYR LLEGEE R+  E   +V+V VS+S   +S GG
Sbjct: 408 EVMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCGG 456


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  394 bits (1012), Expect = e-109
 Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)

Query: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 43  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP FE +I
Sbjct: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY
Sbjct: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQY+DI  +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399

Query: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508
           D+EIATYR LLEGEE R+  E   +V+V VS+S
Sbjct: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  394 bits (1012), Expect = e-109
 Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)

Query: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 43  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP FE +I
Sbjct: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY
Sbjct: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQY+DI  +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399

Query: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508
           D+EIATYR LLEGEE R+  E   +V+V VS+S
Sbjct: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  394 bits (1012), Expect = e-109
 Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)

Query: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 43  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP FE +I
Sbjct: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY
Sbjct: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQY+DI  +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399

Query: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508
           D+EIATYR LLEGEE R+  E   +V+V VS+S
Sbjct: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  394 bits (1012), Expect = e-109
 Identities = 210/393 (53%), Positives = 291/393 (74%), Gaps = 8/393 (2%)

Query: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 43  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 101

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP FE +I
Sbjct: 102 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFEGYI 159

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E++ R  AENEFV +KKDVD AY
Sbjct: 160 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAY 219

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D IIAE+K
Sbjct: 220 LRKSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIK 279

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQY+DI  +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 280 AQYDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 339

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 340 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 399

Query: 476 DLEIATYRTLLEGEESRMSGECAPNVSVSVSTS 508
           D+EIATYR LLEGEE R+  E   +V+V VS+S
Sbjct: 400 DIEIATYRRLLEGEEQRLC-EGVGSVNVCVSSS 431


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  392 bits (1008), Expect = e-109
 Identities = 223/448 (49%), Positives = 308/448 (68%), Gaps = 9/448 (2%)

Query: 120 GGFGSGG--GGFGGGGFGGGGYGGGYGPVCPPGG--IQEVTINQSLLQPLNVEIDPEIQK 175
           GGFGS    GGF  G  G   +G   G VC P    I  V++N+SLL PLN+EIDP  Q 
Sbjct: 48  GGFGSHSVCGGFRAGSCGRS-FGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQC 106

Query: 176 VKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYFESFI 235
           VK  E+EQIKSLN++FA+FIDKVRFLEQQN++L+TK +  Q  +      NLEP F  +I
Sbjct: 107 VKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQS--NLEPLFAGYI 164

Query: 236 NNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDVDGAY 295
             LRR  + +++D  RL SEL ++Q+++E Y+ KYE+E+  R  AENEFV +KKDVD AY
Sbjct: 165 ETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAY 224

Query: 296 MTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSIIAEVK 355
           + K DL+A ++ L QEIDFL  LY+ E+  +Q+ IS+T+V++ +DN+R L++D I+AE+K
Sbjct: 225 LRKSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIK 284

Query: 356 AQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSEIDNV 415
           AQY+DIA +S+AEAES Y+SK EE++ T  RHG+++R +K EI+ELNR+IQRL +E++N 
Sbjct: 285 AQYDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENA 344

Query: 416 KKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNTKLAL 475
           K Q S L+ +++ +EQ+GE AL DA+ KL +LE ALQ+AK+D+A L+R+YQE+MN+KL L
Sbjct: 345 KCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGL 404

Query: 476 DLEIATYRTLLEGEESRM-SGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSSYGS 534
           D+EIATYR LLEGEE R+  G  A NV VS S+    + G     G     GS  S+  +
Sbjct: 405 DIEIATYRRLLEGEEQRLCEGVEAVNVCVS-SSRGGVVCGDLCVSGSRPVTGSVCSAPCN 463

Query: 535 GGGSYGSGGGGGGGRGSYGSGGSSYGSG 562
           G     +G     G+ +   GG S G G
Sbjct: 464 GNLVVSTGLCKPCGQLNTTCGGGSCGQG 491


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.309    0.134    0.378 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,583,416
Number of Sequences: 37866
Number of extensions: 1840822
Number of successful extensions: 118104
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1042
Number of HSP's successfully gapped in prelim test: 868
Number of HSP's that attempted gapping in prelim test: 19802
Number of HSP's gapped (non-prelim): 36747
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.