BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|119120894 Dmx-like 2 [Homo sapiens] (3036 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|119120894 Dmx-like 2 [Homo sapiens] 6159 0.0 gi|148528998 Dmx-like 1 [Homo sapiens] 3245 0.0 gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 64 2e-09 gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 64 2e-09 gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 64 2e-09 gi|19913369 transducin beta-like 3 [Homo sapiens] 59 6e-08 gi|26665869 WD repeat domain 51B [Homo sapiens] 56 5e-07 gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [... 56 6e-07 gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 55 8e-07 gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 55 8e-07 gi|223005862 echinoderm microtubule associated protein like 6 [H... 54 3e-06 gi|21536371 telomerase-associated protein 1 [Homo sapiens] 53 5e-06 gi|13376840 WD repeat domain 61 [Homo sapiens] 52 7e-06 gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 52 1e-05 gi|21071067 TBP-associated factor 5 [Homo sapiens] 51 2e-05 gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H... 51 2e-05 gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] 51 2e-05 gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] 51 2e-05 gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] 51 2e-05 gi|197927448 WD repeat domain 6 protein [Homo sapiens] 50 4e-05 gi|221219020 NYD-SP11 protein [Homo sapiens] 49 8e-05 gi|5174447 guanine nucleotide binding protein (G protein), beta ... 49 8e-05 gi|16554629 WD repeat domain 5 [Homo sapiens] 49 1e-04 gi|16554627 WD repeat domain 5 [Homo sapiens] 49 1e-04 gi|5803221 WD repeat-containing protein 3 [Homo sapiens] 49 1e-04 gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens] 48 2e-04 gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 47 3e-04 gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 47 4e-04 gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is... 47 4e-04 gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i... 47 4e-04 >gi|119120894 Dmx-like 2 [Homo sapiens] Length = 3036 Score = 6159 bits (15978), Expect = 0.0 Identities = 3036/3036 (100%), Positives = 3036/3036 (100%) Query: 1 MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60 MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV Sbjct: 1 MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60 Query: 61 SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120 SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP Sbjct: 61 SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120 Query: 121 QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180 QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD Sbjct: 121 QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180 Query: 181 GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240 GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW Sbjct: 181 GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240 Query: 241 RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR 300 RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR Sbjct: 241 RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR 300 Query: 301 HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI 360 HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI Sbjct: 301 HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI 360 Query: 361 AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD 420 AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD Sbjct: 361 AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD 420 Query: 421 HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL 480 HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL Sbjct: 421 HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL 480 Query: 481 SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV 540 SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV Sbjct: 481 SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV 540 Query: 541 SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS 600 SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS Sbjct: 541 SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS 600 Query: 601 THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS 660 THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS Sbjct: 601 THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS 660 Query: 661 VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA 720 VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA Sbjct: 661 VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA 720 Query: 721 IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA 780 IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA Sbjct: 721 IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA 780 Query: 781 CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT 840 CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT Sbjct: 781 CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT 840 Query: 841 NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD 900 NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD Sbjct: 841 NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD 900 Query: 901 SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS 960 SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS Sbjct: 901 SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS 960 Query: 961 IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS 1020 IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS Sbjct: 961 IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS 1020 Query: 1021 DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG 1080 DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG Sbjct: 1021 DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG 1080 Query: 1081 RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS 1140 RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS Sbjct: 1081 RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS 1140 Query: 1141 VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI 1200 VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI Sbjct: 1141 VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI 1200 Query: 1201 VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL 1260 VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL Sbjct: 1201 VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL 1260 Query: 1261 VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD 1320 VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD Sbjct: 1261 VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD 1320 Query: 1321 VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA 1380 VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA Sbjct: 1321 VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA 1380 Query: 1381 IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD 1440 IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD Sbjct: 1381 IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD 1440 Query: 1441 TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ 1500 TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ Sbjct: 1441 TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ 1500 Query: 1501 YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD 1560 YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD Sbjct: 1501 YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD 1560 Query: 1561 TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI 1620 TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI Sbjct: 1561 TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI 1620 Query: 1621 QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW 1680 QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW Sbjct: 1621 QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW 1680 Query: 1681 GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV 1740 GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV Sbjct: 1681 GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV 1740 Query: 1741 CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL 1800 CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL Sbjct: 1741 CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL 1800 Query: 1801 AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG 1860 AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG Sbjct: 1801 AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG 1860 Query: 1861 TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK 1920 TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK Sbjct: 1861 TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK 1920 Query: 1921 KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE 1980 KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE Sbjct: 1921 KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE 1980 Query: 1981 DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE 2040 DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE Sbjct: 1981 DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE 2040 Query: 2041 QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK 2100 QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK Sbjct: 2041 QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK 2100 Query: 2101 TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS 2160 TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS Sbjct: 2101 TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS 2160 Query: 2161 YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA 2220 YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA Sbjct: 2161 YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA 2220 Query: 2221 NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT 2280 NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT Sbjct: 2221 NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT 2280 Query: 2281 EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL 2340 EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL Sbjct: 2281 EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL 2340 Query: 2341 NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE 2400 NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE Sbjct: 2341 NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE 2400 Query: 2401 NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF 2460 NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF Sbjct: 2401 NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF 2460 Query: 2461 VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH 2520 VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH Sbjct: 2461 VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH 2520 Query: 2521 NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS 2580 NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS Sbjct: 2521 NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS 2580 Query: 2581 VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS 2640 VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS Sbjct: 2581 VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS 2640 Query: 2641 EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW 2700 EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW Sbjct: 2641 EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW 2700 Query: 2701 IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK 2760 IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK Sbjct: 2701 IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK 2760 Query: 2761 RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK 2820 RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK Sbjct: 2761 RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK 2820 Query: 2821 CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC 2880 CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC Sbjct: 2821 CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC 2880 Query: 2881 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA 2940 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA Sbjct: 2881 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA 2940 Query: 2941 HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI 3000 HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI Sbjct: 2941 HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI 3000 Query: 3001 DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL 3036 DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL Sbjct: 3001 DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL 3036 >gi|148528998 Dmx-like 1 [Homo sapiens] Length = 3027 Score = 3245 bits (8413), Expect = 0.0 Identities = 1708/3097 (55%), Positives = 2155/3097 (69%), Gaps = 142/3097 (4%) Query: 1 MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60 M+LHQVLTGAVNPGD+C+SVGS+GD FTAY SGCDIVIL +DFE +QIIPGAKHGNIQV Sbjct: 1 MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV 60 Query: 61 SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120 CV+CS QQG+IAASYGN + IFEP+ + K+N +L QW K+GQFFL S+ +N+ WDP Sbjct: 61 GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP 120 Query: 121 QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180 +RLLT + +QLW+ + E+E ++ T DWKC+W CKT+ VHLM++SPD Sbjct: 121 TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKT-DLNFGDWKCIWHCKTASQVHLMKFSPD 179 Query: 181 GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240 GE+FATAGKDDCLLKVWY + W++++ D K+ Q FSFVYLAHPRAV GFSW Sbjct: 180 GEFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSW 239 Query: 241 RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSI--ASSLSHA 298 RKTSKYMPR SVCNVLLT C D VCRLW ET LP DCLL C T SI ++ Sbjct: 240 RKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRN 299 Query: 299 GRHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHF 358 K+R+Q+ALE +L++ R+G+RRS LV H +P Q H V R+ HANALCHF Sbjct: 300 ASSKERVQNALEV--NLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHF 357 Query: 359 HIAASINPATDIPNVLVGTAFNVDDGN---GGFVVHWLNNKEFHFTSSTEVFMHQLRKLS 415 HIAASINPATDIP + T+ ++++ G FVVHWLNNKE HFT S EVF+ QLRK Sbjct: 358 HIAASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRK-- 415 Query: 416 DKQVDHENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPR 475 ++ E S ED + D+ D E++ G + ++E Sbjct: 416 ---------SFEQPSSEASVEDSNQA-------DVKSDEETDDGVDDLKINPEKKELGCD 459 Query: 476 TYSRLSVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIF 535 S L + +D +IE LL+EW+KN DMLF+IHP+DG+ LVWHV +LDEY PG+F Sbjct: 460 KMVPNSSFTSLSSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMF 519 Query: 536 RQVQVSFSSRIPVAFPSGDASSLSKNIMMYAC-------INATKDSHHTLLHQEGMSVGS 588 RQVQVSF SRIPVAFP+GDA+SL K+IMMYAC I K L M + S Sbjct: 520 RQVQVSFVSRIPVAFPTGDANSLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISS 579 Query: 589 PHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCG 648 H S+S ++I P VMMISKH DGSLNQW V+FA++SAF+TVL++SHK RYCG Sbjct: 580 GHNKS----SNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCG 635 Query: 649 HRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLR 708 HRFHLNDLACHSVLPLLLT+SHHNAL TP++D + D + + S Q + Sbjct: 636 HRFHLNDLACHSVLPLLLTTSHHNALRTPDVD-------NPEQPFDALNIEECSLTQQNK 688 Query: 709 NAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPS 768 + F DP+A+YSELILWRVDP+GPLS++GGVSELARINSLH SAFSNVAWLPTLIPS Sbjct: 689 STVDVAFQDPSAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPS 748 Query: 769 YCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTA 828 YCLG YCNS SACFVASDG+ LRLY+AV+DA+KLL ELS+PE SK +GEVFNIVSQQSTA Sbjct: 749 YCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLSELSNPEISKYVGEVFNIVSQQSTA 808 Query: 829 RPGCIIELDAITNQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKET-EIFFQPSQGYRPPP 887 RPGCII LD IT G TQLLHVF+EDFI+ ++EKK + + G P Sbjct: 809 RPGCIIALDPITKLHGRKTQLLHVFEEDFILN------NLEKKSLGKDSILSNAGSSPNG 862 Query: 888 FSEKFFLVVIEKDSNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPE 947 FSEKF+L+VIE +N S+LHMW+LHLKS+ L + + SE++ +++ SSPE Sbjct: 863 FSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKVDTKLSEAVWQP--EEHYSSSPE 920 Query: 948 TSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYP 1007 S + + ANLQ+ S+L L S +VYSQ L LPE VE+I PSAGHLSSSSIYP Sbjct: 921 KILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEGVEIISIKPSAGHLSSSSIYP 980 Query: 1008 VCLAPYLVVTTCSDNKVRFWKCCMEANPECNKSDEKE--IYHWKRWPLMNDEGEDNSSTV 1065 C APYL+ T+CSD KVRFW+C + + K Y W+ WPL+ ++G ++S++ Sbjct: 981 ACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLAYIWEEWPLLIEDGLQSNSSI 1040 Query: 1066 SIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHL 1125 ++ GRPV VSC++T RLAVAYKQP N S++F MHV IFECESTGGS WVLEQTIHL Sbjct: 1041 TVPGRPVEVSCAHTNRLAVAYKQPAS-NSRSSQDFVMHVSIFECESTGGSCWVLEQTIHL 1099 Query: 1126 DDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTV 1185 D+L +VLDS +SVDSNL Y+K D LS + N KHLVHLDW+S+EDGSHILTV Sbjct: 1100 DEL---STVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLVHLDWMSREDGSHILTV 1156 Query: 1186 GVGANIFMYGRLSGIVTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGT 1245 G+G+ +FMYG L+G V +QT G + PL S K S++VLLRS+DLVSSVDG+ Sbjct: 1157 GIGSKLFMYGPLAGKVQDQT----GKETLAFPLWESTKVVPLSKFVLLRSVDLVSSVDGS 1212 Query: 1246 PSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDTEADS--------------SNAE 1291 P PVSLSWVRDGILVVGMDCEMHVY QW+ + K DS SN+ Sbjct: 1213 PPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTPSITSLIKQSNSS 1272 Query: 1292 EAAMQDHSTFKSNM--LARKSVVEGTAISDDVFCSPTVIQDGGLFEAAHVLSPTLPQYHP 1349 T +M LA+K + TA V ++D GLFEAAHVLSPTLPQYHP Sbjct: 1273 SGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVD-----MEDSGLFEAAHVLSPTLPQYHP 1327 Query: 1350 TQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKET 1409 QLLELMDLGKVRRAKAILSHLVKCIAGEV + + ++ +R S TIS SGST ++ Sbjct: 1328 LQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNH-ERRLRSLTISASGSTTRDP 1386 Query: 1410 VTVGKDGTRDYTEIDSIPPLPLYALLAADQDTSYRISEESTKIPQSYEDQTVSQPEDQYS 1469 K DYTEIDS+PPLPLYALLAAD D+ Y E+S+ +S ++ ++ Y Sbjct: 1387 QAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSN--ESTLSKSNQLSKESYD 1444 Query: 1470 ELFQIQDIPTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRL 1529 ELFQ Q + TD LE ++ K +VI+LSQY P YFG EHA+VLS HL+HSSLPGL+R+ Sbjct: 1445 ELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRM 1504 Query: 1530 EQMFLVALADTVATTSTELDESRDKSCSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRV 1589 EQM L+ALADT+ATTST++ ESRD+S G +TLDECGL++LLA+RLHT L TSLP YR Sbjct: 1505 EQMSLMALADTIATTSTDIGESRDRS-QGGETLDECGLKFLLAVRLHTFLTTSLPA-YRA 1562 Query: 1590 QLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCI 1649 QLLHQG+ST HFAWAFHS AEEEL+NM+PA+Q+ DP WSELRAMG+GWWVRN LR+CI Sbjct: 1563 QLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCI 1622 Query: 1650 EKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAAL 1709 EKVAKA+F R ND LDAA+FYL+MKKKAV+WGL+R++ + +MT FF HNF ++RWRKAAL Sbjct: 1623 EKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKAAL 1682 Query: 1710 KNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSSTYI 1769 KNAFSLLGKQRFE SAAFFLLAG L+DAIEVCLEK+ DIQLA+VIARLYESEF+TS+ Y Sbjct: 1683 KNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAAYK 1742 Query: 1770 SILNQKILGCQKDGSGFSCK---RLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEH 1826 SIL +K+LG S C +H DPFLRS+AYW+++DY+ AL+TL++Q +E+D+ Sbjct: 1743 SILRKKVLGIDSPVSEL-CSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDDQ 1801 Query: 1827 QVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFF 1886 ++ + NP F+FYNYLRTHPLL+RR+ S + + L + INL ER+LFF Sbjct: 1802 --VLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFF 1859 Query: 1887 TTANAHFKVGCPVLALEVLSKIPKVTK--------TSALSAKKD----QPDFISHRMD-- 1932 TTA+AH K GCP+LALEVLSK+PKV K +S L KD P + R D Sbjct: 1860 TTASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKS 1919 Query: 1933 DVPSHSKALSDGNGSS---GIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGEDHDSALDEE 1989 S++L +G GSS E + ++ +DWSQP V ++ L L W D+D +E Sbjct: 1920 SAVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDND---EEN 1976 Query: 1990 EDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAEQLKFRACLK 2049 ED + + R+ DK+ D +S+ + +E+D +E D+IA QLKFRACLK Sbjct: 1977 EDVPISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSE-DIIAVQLKFRACLK 2035 Query: 2050 ILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESDL 2109 IL ELRTL+TGYE+DGGKLR+QLY+WLEKE+ AL C+ S +E S + + E + Sbjct: 2036 ILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQS-AFGRNEDEF 2094 Query: 2110 LDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQG 2169 E+ D P HQ + ++L RE+ + ++ WL K Q LLR+FLSYC LHG+ G Sbjct: 2095 GLNEDAEDLP-------HQTKVKQL---RENFQEKRQWLLKYQSLLRMFLSYCILHGSHG 2144 Query: 2170 GGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNH 2229 GGLASVRMEL LLQESQQET+ SPL T++PLL A A+ KTV+ANP+L+L+N Sbjct: 2145 GGLASVRMELILLLQESQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNL 2204 Query: 2230 IHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMA 2289 HDIL+ I+ +PPHP I+ KV+ +H+LAASLSA IYQ LC SH+YS + NQFTGM Sbjct: 2205 THDILHAIINFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMV 2264 Query: 2290 YQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVV 2349 YQ +LL R L+T S++E TPN+SPAQWPG++ LI LL+S+ +E Q L +LLCE + Sbjct: 2265 YQTVLLPHRPSLKTGSLDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILT 2324 Query: 2350 AVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSENISAPPVLS 2409 AVYLSL IH LAT+SS+ELFR+ AHPLN +MW+AVFGGG + K + S+ + ++ Sbjct: 2325 AVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVE 2384 Query: 2410 EDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLS 2469 E +++R +M + PV E + KEKFIPPELS+WDYF+AKPFLP S Sbjct: 2385 EGEKQNKRFRPSKMSCRESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSS 2444 Query: 2470 DSGVIYDSDESIHS-----DEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKN 2524 S YDS+ES+ S D++DD SD +QEH + NSYSW+L+ L MV+L L+N+K Sbjct: 2445 QSRAEYDSEESLGSDDDDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKT 2504 Query: 2525 FFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAG 2584 F+P AG + +ELPV+SPL AV+K L+ WEQ+L +++ GPP NYI ++ + S+ AG Sbjct: 2505 FYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAG 2564 Query: 2585 PAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEA 2644 PAILR+KA+LEP NTPFKS+ A VKRLW +LVKQE +QETFI+ IFTKKR +E+EA Sbjct: 2565 PAILRHKALLEPTNTPFKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEA 2624 Query: 2645 DLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEE 2704 DLGYPGGKA++IHKESD+I AF+VNKAN N I +AS+HDVQELDV+ +LA Q Y W+ ++ Sbjct: 2625 DLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDD 2684 Query: 2705 YDRESKSSDD---VDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMKR 2761 + E+K S+D + R T + T Y+ S P ++PWLG+ QT GASV++K+ Sbjct: 2685 IEVETKGSEDFLVIHARDDLTAV--QGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKK 2742 Query: 2762 NLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKC 2821 ++NV+RMTSHP YYLTGAQDGSVRMFEW QQ+ CFR GN+RVTR+ FN QGNK Sbjct: 2743 AINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKF 2802 Query: 2822 GVADGEGFLSIWQVN-----QTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDN 2876 G+ D +G+LS++Q N T S PKPY++WQCH+K +DF F++SSSL+AT+G S DN Sbjct: 2803 GIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDN 2862 Query: 2877 RNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIH 2936 RNVCLWDTL++P NSL+H FTCHD GATVL YAPK QLLISGGRKG +FD+ QRQ Sbjct: 2863 RNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQ 2922 Query: 2937 TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAG 2996 FQ+HDS +KA+A+DP EEYF TGSAEGNIK+W L+ GL+H+F SEHA+QSIFRNIG G Sbjct: 2923 LFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTG 2982 Query: 2997 VMQIDIIQGNRLFSCGADGTLKTRVLPNAFNIPNRIL 3033 VMQI+ N +FSCGADGT+K R+LP+ F+ N +L Sbjct: 2983 VMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVL 3019 >gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] Length = 369 Score = 63.9 bits (154), Expect = 2e-09 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839 +G++D +VR++ + FR A A V ++F S G A + + +W ++ Sbjct: 40 SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 98 Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897 + +++W +K + D I S+S D++ V LWD +H + Sbjct: 99 FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 146 Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957 H T + + P + + G V ++D+R +L+ +Q H +A+ L+ P Y Sbjct: 147 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 206 Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979 T S++ +K+ L L+++ Sbjct: 207 ITASSDSTLKILDLMEGRLLYT 228 Score = 50.1 bits (118), Expect = 3e-05 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%) Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813 G S + + + V+ + Q ++T + D +V+++ R + L Q N V Sbjct: 56 GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 114 Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873 F+ G A + + +W S+ + S+ H + F S + +A +G Sbjct: 115 FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 170 Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933 N V +WD + L+ + H L + P LI+ + I D+ + + Sbjct: 171 N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 224 Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 L++T H +A EYF +G ++ + VW+ Sbjct: 225 LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 261 Score = 43.5 bits (101), Expect = 0.003 Identities = 42/228 (18%), Positives = 85/228 (37%), Gaps = 20/228 (8%) Query: 2792 WTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQC 2850 W Q +R G+ VT + F+ G+ + + IW N + ++ Sbjct: 8 WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV----FRA 63 Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910 H+ F + T+ +D++ V +W T + + H + +++P Sbjct: 64 HTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQHINWVRCAKFSP 117 Query: 2911 KQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 +L++S V ++D R+ +H++ H + + P + +KVW Sbjct: 118 DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177 Query: 2971 LTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018 + H L+ ++ A + G GN L + +D TLK Sbjct: 178 VRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 216 >gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] Length = 359 Score = 63.9 bits (154), Expect = 2e-09 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839 +G++D +VR++ + FR A A V ++F S G A + + +W ++ Sbjct: 78 SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136 Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897 + +++W +K + D I S+S D++ V LWD +H + Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 184 Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957 H T + + P + + G V ++D+R +L+ +Q H +A+ L+ P Y Sbjct: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244 Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979 T S++ +K+ L L+++ Sbjct: 245 ITASSDSTLKILDLMEGRLLYT 266 Score = 50.1 bits (118), Expect = 3e-05 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%) Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813 G S + + + V+ + Q ++T + D +V+++ R + L Q N V Sbjct: 94 GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 152 Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873 F+ G A + + +W S+ + S+ H + F S + +A +G Sbjct: 153 FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208 Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933 N V +WD + L+ + H L + P LI+ + I D+ + + Sbjct: 209 N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 262 Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 L++T H +A EYF +G ++ + VW+ Sbjct: 263 LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299 Score = 43.9 bits (102), Expect = 0.002 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 22/240 (9%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 +G+ D + + W Q +R G+ VT + F+ G+ + + IW N Sbjct: 36 SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 + ++ H+ F + T+ +D++ V +W T + + Sbjct: 94 GESTV----FRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQ 143 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H + +++P +L++S V ++D R+ +H++ H + + P Sbjct: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIA 203 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018 + +KVW + H L+ ++ A + G GN L + +D TLK Sbjct: 204 AAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 254 Score = 38.9 bits (89), Expect = 0.078 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Query: 2867 VATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCI 2926 + T ++ + + CL + P S + FT H T + ++P LL SG R V I Sbjct: 29 INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87 Query: 2927 FDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 + + F+AH + ++++ + F T S + +KVW Sbjct: 88 WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 33.5 bits (75), Expect = 3.3 Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%) Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950 SL F H T + ++ + L SG + ++ ++ + + F H A+ + Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69 Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFS 3010 P +GS + +++W + + K E ++FR A V + + F Sbjct: 70 SPSGHLLASGSRDKTVRIW-------VPNVKGE---STVFRAHTATVRSVHFCSDGQSFV 119 Query: 3011 CGAD 3014 +D Sbjct: 120 TASD 123 >gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] Length = 407 Score = 63.9 bits (154), Expect = 2e-09 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839 +G++D +VR++ + FR A A V ++F S G A + + +W ++ Sbjct: 78 SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136 Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897 + +++W +K + D I S+S D++ V LWD +H + Sbjct: 137 FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 184 Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957 H T + + P + + G V ++D+R +L+ +Q H +A+ L+ P Y Sbjct: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244 Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979 T S++ +K+ L L+++ Sbjct: 245 ITASSDSTLKILDLMEGRLLYT 266 Score = 50.1 bits (118), Expect = 3e-05 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%) Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813 G S + + + V+ + Q ++T + D +V+++ R + L Q N V Sbjct: 94 GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 152 Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873 F+ G A + + +W S+ + S+ H + F S + +A +G Sbjct: 153 FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208 Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933 N V +WD + L+ + H L + P LI+ + I D+ + + Sbjct: 209 N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 262 Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 L++T H +A EYF +G ++ + VW+ Sbjct: 263 LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299 Score = 43.9 bits (102), Expect = 0.002 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 22/240 (9%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 +G+ D + + W Q +R G+ VT + F+ G+ + + IW N Sbjct: 36 SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 + ++ H+ F + T+ +D++ V +W T + + Sbjct: 94 GESTV----FRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQ 143 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H + +++P +L++S V ++D R+ +H++ H + + P Sbjct: 144 HINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIA 203 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018 + +KVW + H L+ ++ A + G GN L + +D TLK Sbjct: 204 AAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 254 Score = 38.9 bits (89), Expect = 0.078 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 1/103 (0%) Query: 2867 VATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCI 2926 + T ++ + + CL + P S + FT H T + ++P LL SG R V I Sbjct: 29 INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87 Query: 2927 FDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 + + F+AH + ++++ + F T S + +KVW Sbjct: 88 WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130 Score = 33.5 bits (75), Expect = 3.3 Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%) Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950 SL F H T + ++ + L SG + ++ ++ + + F H A+ + Sbjct: 10 SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69 Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFS 3010 P +GS + +++W + + K E ++FR A V + + F Sbjct: 70 SPSGHLLASGSRDKTVRIW-------VPNVKGE---STVFRAHTATVRSVHFCSDGQSFV 119 Query: 3011 CGAD 3014 +D Sbjct: 120 TASD 123 >gi|19913369 transducin beta-like 3 [Homo sapiens] Length = 808 Score = 59.3 bits (142), Expect = 6e-08 Identities = 55/272 (20%), Positives = 110/272 (40%), Gaps = 32/272 (11%) Query: 2735 SQVHPPSSLPWLGTGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTR 2794 S V S+ P L + T A ++ + V + + + A+D SVR++ + Sbjct: 348 SHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNK 407 Query: 2795 PQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFL---------SIWQV------NQTA 2839 Q++C Q + +S G C E FL +W + TA Sbjct: 408 AGQVMCVAQGSG------HTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTA 461 Query: 2840 SNPKPYM-----SWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIH 2894 + P + + +CH K + A + L+AT + +R LW P L+ Sbjct: 462 PDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATG---SQDRTAKLWAL---PQCQLLG 515 Query: 2895 GFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYE 2954 F+ H G +Q++P Q+L + G + ++ ++ + TF+ HD+++ +A Sbjct: 516 VFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRG 575 Query: 2955 EYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAK 2986 + ++G +K+W + + + + + K Sbjct: 576 TQLLSSGSDGLVKLWTIKNNECVRTLDAHEDK 607 Score = 58.5 bits (140), Expect = 1e-07 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 11/128 (8%) Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957 CHD + AP +LL +G + ++ + Q QL+ F H + + P ++ Sbjct: 477 CHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVL 536 Query: 2958 TTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDII-QGNRLFSCGADGT 3016 T SA+G IK+W L + +F+ A V+++ + +G +L S G+DG Sbjct: 537 ATASADGTIKLWALQDFSCLKTFEGH----------DASVLKVAFVSRGTQLLSSGSDGL 586 Query: 3017 LKTRVLPN 3024 +K + N Sbjct: 587 VKLWTIKN 594 Score = 45.1 bits (105), Expect = 0.001 Identities = 42/209 (20%), Positives = 86/209 (41%), Gaps = 26/209 (12%) Query: 2777 YYLTGAQDGSVRMFEWTRPQQLVCFRQAGN-------ARVTRLYFNSQGNKCGVADGEGF 2829 + +TG+QD +V++ W P+ L+ A + A+ T+ + N +A + Sbjct: 436 FLVTGSQDCTVKL--WPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKL 493 Query: 2830 LSIWQVNQTASNPKPYMSWQC--------HSKATSDFAFITSSSLVATSGHSNDNRNVCL 2881 L+ ++TA K + QC H + F ++AT+ + L Sbjct: 494 LATGSQDRTA---KLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL 550 Query: 2882 WDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAH 2941 D S + F HD + + + L+S G G V ++ I+ + + T AH Sbjct: 551 QDF------SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 604 Query: 2942 DSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 + + L +++ TG+++ + +W+ Sbjct: 605 EDKVWGLHCSRLDDHALTGASDSRVILWK 633 Score = 35.8 bits (81), Expect = 0.66 Identities = 17/79 (21%), Positives = 37/79 (46%), Gaps = 1/79 (1%) Query: 2904 TVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA-HDSAIKALALDPYEEYFTTGSA 2962 T +P ++L++ R + + ++ + ++A H + + +A DP TG Sbjct: 70 TAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGC 129 Query: 2963 EGNIKVWRLTGHGLIHSFK 2981 +G ++VW + H H F+ Sbjct: 130 DGAVRVWDIVRHYGTHHFR 148 Score = 32.3 bits (72), Expect = 7.3 Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 2/75 (2%) Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL--DPYEEY 2956 H + + P LL +GG G V ++DI + H F+ + +A DP Sbjct: 108 HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167 Query: 2957 FTTGSAEGNIKVWRL 2971 + + + I+VW L Sbjct: 168 LFSSATDAAIRVWSL 182 Score = 32.0 bits (71), Expect = 9.6 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 12/84 (14%) Query: 2897 TCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEE- 2955 T H T L ++ ++S GR I+D++ Q T +S ++A L P E Sbjct: 192 TAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFES-VEAAVLLPEEPV 250 Query: 2956 ----------YFTTGSAEGNIKVW 2969 YF T +G ++VW Sbjct: 251 SQLGVKSPGLYFLTAGDQGTLRVW 274 >gi|26665869 WD repeat domain 51B [Homo sapiens] Length = 478 Score = 56.2 bits (134), Expect = 5e-07 Identities = 49/229 (21%), Positives = 92/229 (40%), Gaps = 40/229 (17%) Query: 2776 QYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQV 2835 Q+ T ++D S++++ R + L LY ++ +C +G L + Sbjct: 115 QFLATASEDKSIKVWSMYRQRFLYS-----------LYRHTHWVRCAKFSPDGRLIV--- 160 Query: 2836 NQTASNPKPYMSW-----QCHSKATSDFAFIT------SSSLVATSGHSNDNRNVCLWDT 2884 + S K W QC + + F S + +A++G ++ V +WD Sbjct: 161 --SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAG---SDQTVKVWDV 215 Query: 2885 LISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSA 2944 + N L+ + H G + + P LI+ G + I D+ + +LI+T Q H Sbjct: 216 RV---NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP 272 Query: 2945 IKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNI 2993 + ++ E F +G A+ + +WR +F H K RN+ Sbjct: 273 VFTVSFSKGGELFASGGADTQVLLWRT-------NFDELHCKGLTKRNL 314 Score = 44.3 bits (103), Expect = 0.002 Identities = 40/229 (17%), Positives = 88/229 (38%), Gaps = 22/229 (9%) Query: 2792 WTRPQQLVCFRQAGNARV-TRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQC 2850 W +R G+ V T + F+ GN A + + +W ++ + ++ Sbjct: 45 WNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGK----FSEFKA 100 Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910 H+ F +AT+ ++++++ +W ++ H H +++P Sbjct: 101 HTAPVRSVDFSADGQFLATA---SEDKSIKVWSMY---RQRFLYSLYRHTHWVRCAKFSP 154 Query: 2911 KQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970 +L++S + I+D +Q ++ F + +P + ++ +KVW Sbjct: 155 DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214 Query: 2971 LTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDII-QGNRLFSCGADGTLK 3018 + + L+ ++ GV I GN L + +DGTLK Sbjct: 215 VRVNKLLQHYQVH----------SGGVNCISFHPSGNYLITASSDGTLK 253 Score = 41.2 bits (95), Expect = 0.016 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 4/102 (3%) Query: 2882 WDTLISPGNSLIHG----FTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHT 2937 WDT + N H + H T +Q++P LL S R V ++ +R Sbjct: 38 WDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSE 97 Query: 2938 FQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHS 2979 F+AH + ++++ ++ T S + +IKVW + ++S Sbjct: 98 FKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139 >gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [Homo sapiens] Length = 340 Score = 55.8 bits (133), Expect = 6e-07 Identities = 52/236 (22%), Positives = 93/236 (39%), Gaps = 16/236 (6%) Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 ++ +QDG + +++ ++ + +T Y S GN + SI+ + Sbjct: 71 VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTR 129 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 N + H+ S F+ + ++ +SG + LWD I G + GF Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT----CALWD--IETGQQTV-GFAG 182 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H L AP + +SG + ++D+R TF H+S I A+A P FT Sbjct: 183 HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFT 242 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014 TGS + +++ L + + + NI G+ + + RL G D Sbjct: 243 TGSDDATCRLFDLRADQELLMYSHD--------NIICGITSVAFSRSGRLLLAGYD 290 >gi|83779014 katanin p80 subunit B 1 [Homo sapiens] Length = 655 Score = 55.5 bits (132), Expect = 8e-07 Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 6/119 (5%) Query: 2863 SSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKG 2922 S L+AT G D+ V LW I+ N ++ T H ++ ++L+++G + G Sbjct: 32 SGRLLATGG---DDCRVNLWS--INKPNCIM-SLTGHTSPVESVRLNTPEELIVAGSQSG 85 Query: 2923 HVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFK 2981 + ++D+ +++ T H + I +L PY E+ +GS + NIK+W + G + ++ Sbjct: 86 SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR 144 Score = 38.9 bits (89), Expect = 0.078 Identities = 20/73 (27%), Positives = 36/73 (49%) Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLT 2972 +LL +GG V ++ I + I + H S ++++ L+ EE GS G+I+VW L Sbjct: 34 RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93 Query: 2973 GHGLIHSFKSEHA 2985 ++ + A Sbjct: 94 AAKILRTLMGHKA 106 Score = 38.9 bits (89), Expect = 0.078 Identities = 35/204 (17%), Positives = 72/204 (35%), Gaps = 11/204 (5%) Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839 TG D V ++ +P ++ + V + N+ G + +W + Sbjct: 38 TGGDDCRVNLWSINKPNCIMSLT-GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA- 95 Query: 2840 SNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCH 2899 K + H F VA+ + + N+ LWD + + H Sbjct: 96 ---KILRTLMGHKANICSLDFHPYGEFVASG---SQDTNIKLWDIR---RKGCVFRYRGH 146 Query: 2900 DHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTT 2959 L+++P + L S V ++D+ +++ F H + + P E + Sbjct: 147 SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206 Query: 2960 GSAEGNIKVWRLTGHGLIHSFKSE 2983 GS++ I+ W L ++ + E Sbjct: 207 GSSDRTIRFWDLEKFQVVSCIEGE 230 >gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [Homo sapiens] Length = 340 Score = 55.5 bits (132), Expect = 8e-07 Identities = 52/236 (22%), Positives = 92/236 (38%), Gaps = 16/236 (6%) Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 ++ +QDG + +++ ++ + +T Y S GN + SI+ + Sbjct: 71 VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTR 129 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 N + H+ S F+ + +V +SG + LWD I G FT Sbjct: 130 EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT----CALWD--IETGQQTTT-FTG 182 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H L AP +L +SG ++D+R+ TF H+S I A+ P F Sbjct: 183 HTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA 242 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014 TGS + +++ L + ++ + NI G+ + + RL G D Sbjct: 243 TGSDDATCRLFDLRADQELMTYSHD--------NIICGITSVSFSKSGRLLLAGYD 290 >gi|223005862 echinoderm microtubule associated protein like 6 [Homo sapiens] Length = 1958 Score = 53.5 bits (127), Expect = 3e-06 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 12/146 (8%) Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910 H+ A +LVAT G +C+WD+ SL+ H HG L + Sbjct: 60 HNDDIISLALHPDKTLVAT-GQVGKEPYICIWDSYNVQTVSLLKDV--HTHGVACLAFDS 116 Query: 2911 KQQLLISGG--RKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKV 2968 Q L S G K VCI+D R+ +L+ + H I ++ DPY+ +IK Sbjct: 117 DGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRVVSCGVKHIKF 176 Query: 2969 WRLTGHGLIHSFKSEHAKQSIFRNIG 2994 W L G+ L AK+ IF G Sbjct: 177 WTLCGNALT-------AKRGIFGKTG 195 Score = 40.8 bits (94), Expect = 0.021 Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 5/131 (3%) Query: 2864 SSLVATSGHSNDNRNVC--LWDTLISPGNSLIHGFTCHDH-GATVLQYAPKQQLLISGGR 2920 S G + R+ C LWDT P + T + G ++ K L++G + Sbjct: 242 SMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQ 301 Query: 2921 KGHVCIFDIRQRQL-IHTFQAH-DSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIH 2978 + +R+R + Q H + + ALAL P + TGS + ++++W L H LI Sbjct: 302 DSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIA 361 Query: 2979 SFKSEHAKQSI 2989 E A +S+ Sbjct: 362 RCNMEEAVRSV 372 >gi|21536371 telomerase-associated protein 1 [Homo sapiens] Length = 2627 Score = 52.8 bits (125), Expect = 5e-06 Identities = 39/120 (32%), Positives = 54/120 (45%), Gaps = 7/120 (5%) Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGF-TCHDHGATVLQYA 2909 H S +F T +AT G +R++ WD LIH F CH T + Sbjct: 2060 HEGPVSCCSFSTDGGSLATGGR---DRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 2116 Query: 2910 PKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 K LLIS G V ++D Q + F H SA+ A+A EE+ + S +G +KVW Sbjct: 2117 -KDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVA--AVEEHVVSVSRDGTLKVW 2173 >gi|13376840 WD repeat domain 61 [Homo sapiens] Length = 305 Score = 52.4 bits (124), Expect = 7e-06 Identities = 24/89 (26%), Positives = 46/89 (51%) Query: 2892 LIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALD 2951 L+H H L ++P QLL++ G++ I+D++ L T H S + +A Sbjct: 182 LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241 Query: 2952 PYEEYFTTGSAEGNIKVWRLTGHGLIHSF 2980 P + +F + S++ ++KVW + +H+F Sbjct: 242 PDDTHFVSSSSDKSVKVWDVGTRTCVHTF 270 Score = 47.4 bits (111), Expect = 2e-04 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%) Query: 2906 LQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGN 2965 + Y+P + L SG G + IFDI +L+HT + H I++L P + T S +G Sbjct: 154 IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213 Query: 2966 IKVWRLTGHGLIHSFKSEHA 2985 IK++ + H + S HA Sbjct: 214 IKIYDVQ-HANLAGTLSGHA 232 >gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] Length = 357 Score = 51.6 bits (122), Expect = 1e-05 Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 18/205 (8%) Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873 F+ G+ A + + +W V N Y + + HS A + + T S++ ++ Sbjct: 74 FHPNGSTLASAGFDRLILLWNVYGDCDN---YATLKGHSGAVMELHYNTDGSMLFSA--- 127 Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933 + ++ V +WD+ + G T + + P QL+ +G G V ++DIR++ Sbjct: 128 STDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP--QLVCTGSDDGTVKLWDIRKKA 185 Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNI 2993 I TFQ + + A+ + + +G + +IKVW L + L ++ + HA ++ Sbjct: 186 AIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG-HADSVTGLSL 243 Query: 2994 GAGVMQIDIIQGNRLFSCGADGTLK 3018 + +G+ L S D T++ Sbjct: 244 SS--------EGSYLLSNAMDNTVR 260 Score = 44.3 bits (103), Expect = 0.002 Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 10/161 (6%) Query: 2809 VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVA 2868 V L++N+ G+ A + +++W ++T K S S + LV Sbjct: 112 VMELHYNTDGSMLFSASTDKTVAVWD-SETGERVKRLKGHT--SFVNSCYPARRGPQLVC 168 Query: 2869 TSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFD 2928 T +D+ V LWD + I F + + + + +ISGG + ++D Sbjct: 169 TG---SDDGTVKLWDIR---KKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWD 221 Query: 2929 IRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 +RQ +L +T + H ++ L+L Y + + + ++VW Sbjct: 222 LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVW 262 >gi|21071067 TBP-associated factor 5 [Homo sapiens] Length = 800 Score = 51.2 bits (121), Expect = 2e-05 Identities = 44/197 (22%), Positives = 81/197 (41%), Gaps = 11/197 (5%) Query: 2773 PVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSI 2832 P Y L+ ++DG+VR++ LV ++ N V F+ G + + Sbjct: 553 PDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARL 611 Query: 2833 WQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSL 2892 W + +P + H + F +S+ VAT + +R V LWD L + Sbjct: 612 WATDHY----QPLRIFAGHLADVNCTRFHPNSNYVATG---SADRTVRLWDVL---NGNC 661 Query: 2893 IHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDP 2952 + FT H L ++P + L +G G V ++DI ++ + H + +L Sbjct: 662 VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721 Query: 2953 YEEYFTTGSAEGNIKVW 2969 E +GS + +++W Sbjct: 722 DGEILASGSMDNTVRLW 738 Score = 38.5 bits (88), Expect = 0.10 Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 13/117 (11%) Query: 2873 SNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQR 2932 S+++ V LW + + G+ H++ Q++P +SGG ++ Sbjct: 561 SSEDGTVRLWSLQTF---TCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY 617 Query: 2933 QLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRL---------TGH-GLIHS 2979 Q + F H + + P Y TGSA+ +++W + TGH G IHS Sbjct: 618 QPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHS 674 >gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo sapiens] Length = 340 Score = 50.8 bits (120), Expect = 2e-05 Identities = 51/236 (21%), Positives = 90/236 (38%), Gaps = 16/236 (6%) Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 ++ +QDG + +++ ++ + +T Y S GN + SI+ + Sbjct: 71 VSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSR 129 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 N K H+ S F+ +++V +SG + LWD ++ G Sbjct: 130 EGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTT----CALWDIETGQQKTVFVG--- 182 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H L +P L ISG ++D+R+ TF H+S I A+ P E Sbjct: 183 HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014 TGS + + +++ L + F E +I G+ + RL G D Sbjct: 243 TGSDDASCRLFDLRADQELICFSHE--------SIICGITSVAFSLSGRLLFAGYD 290 >gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens] Length = 919 Score = 50.8 bits (120), Expect = 2e-05 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%) Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916 A T S + SG + ++ V WD + P + G T H G+ V A P +LL Sbjct: 760 ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 816 Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973 +G ++DIR +++ ++ H S ++++ P Y TGS + IKV L G Sbjct: 817 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 873 Score = 38.9 bits (89), Expect = 0.078 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%) Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813 V+ + HP Y G+ ++R+ + T Q +V F++ + + + + Sbjct: 609 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 668 Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869 ++ G + ++ + N +T + P + + H D AF+ S + Sbjct: 669 WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 728 Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929 S + D N+ D G + G T H + Y ++ SG + V +D+ Sbjct: 729 SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 783 Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985 R + TF SA+ ++A+DP TG + + ++ + G ++ S+ H Sbjct: 784 RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 840 Query: 2986 KQSIFRNI 2993 S R++ Sbjct: 841 HSSDVRSV 848 >gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens] Length = 927 Score = 50.8 bits (120), Expect = 2e-05 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%) Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916 A T S + SG + ++ V WD + P + G T H G+ V A P +LL Sbjct: 768 ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 824 Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973 +G ++DIR +++ ++ H S ++++ P Y TGS + IKV L G Sbjct: 825 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 881 Score = 38.9 bits (89), Expect = 0.078 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%) Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813 V+ + HP Y G+ ++R+ + T Q +V F++ + + + + Sbjct: 617 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 676 Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869 ++ G + ++ + N +T + P + + H D AF+ S + Sbjct: 677 WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 736 Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929 S + D N+ D G + G T H + Y ++ SG + V +D+ Sbjct: 737 SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 791 Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985 R + TF SA+ ++A+DP TG + + ++ + G ++ S+ H Sbjct: 792 RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 848 Query: 2986 KQSIFRNI 2993 S R++ Sbjct: 849 HSSDVRSV 856 >gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens] Length = 920 Score = 50.8 bits (120), Expect = 2e-05 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%) Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916 A T S + SG + ++ V WD + P + G T H G+ V A P +LL Sbjct: 761 ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 817 Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973 +G ++DIR +++ ++ H S ++++ P Y TGS + IKV L G Sbjct: 818 TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 874 Score = 38.9 bits (89), Expect = 0.078 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%) Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813 V+ + HP Y G+ ++R+ + T Q +V F++ + + + + Sbjct: 610 VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 669 Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869 ++ G + ++ + N +T + P + + H D AF+ S + Sbjct: 670 WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 729 Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929 S + D N+ D G + G T H + Y ++ SG + V +D+ Sbjct: 730 SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 784 Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985 R + TF SA+ ++A+DP TG + + ++ + G ++ S+ H Sbjct: 785 RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 841 Query: 2986 KQSIFRNI 2993 S R++ Sbjct: 842 HSSDVRSV 849 >gi|197927448 WD repeat domain 6 protein [Homo sapiens] Length = 1151 Score = 49.7 bits (117), Expect = 4e-05 Identities = 33/120 (27%), Positives = 60/120 (50%), Gaps = 7/120 (5%) Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDT--LISPGNSLIHGFTCHDHGATVLQYAPKQQLLI 2916 +++ S L+AT+ +++R+V +W L PG + + C H A V Q + LI Sbjct: 246 SYLESKGLLATA---SEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLI 302 Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDS-AIKALALDPYEEYFTTGSAEGNIKVWRLTGHG 2975 S G + VC+ + +++ F+ H I+A+A + + TG + I++W L G G Sbjct: 303 SAG-EDCVCLVWSHEGEILQAFRGHQGRGIRAIAAHERQAWVITGGDDSGIRLWHLVGRG 361 >gi|221219020 NYD-SP11 protein [Homo sapiens] Length = 2873 Score = 48.9 bits (115), Expect = 8e-05 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 11/94 (11%) Query: 2884 TLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDS 2943 T S G+S+ FTC D G L +G + G + ++ ++Q +H+FQAH S Sbjct: 197 TSTSSGSSITCCFTCFDQG-----------FLYAGNQAGEIQVWSLQQGHPLHSFQAHQS 245 Query: 2944 AIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLI 2977 + + P T ++ IK W LT L+ Sbjct: 246 GVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLL 279 >gi|5174447 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [Homo sapiens] Length = 317 Score = 48.9 bits (115), Expect = 8e-05 Identities = 50/213 (23%), Positives = 85/213 (39%), Gaps = 20/213 (9%) Query: 2776 QYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQ 2834 Q+ L+G+ DG++R+ W R G+ + V + F+S + + + +W Sbjct: 76 QFALSGSWDGTLRL--WDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW- 132 Query: 2835 VNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGN---- 2890 T K + + HS+ S F +S SN C WD L+ N Sbjct: 133 --NTLGVCKYTVQDESHSEWVSCVRFSPNS--------SNPIIVSCGWDKLVKVWNLANC 182 Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950 L H + +P L SGG+ G ++D+ + + ++T D I AL Sbjct: 183 KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-IINALCF 241 Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSE 2983 P Y+ + +IK+W L G ++ K E Sbjct: 242 SP-NRYWLCAATGPSIKIWDLEGKIIVDELKQE 273 >gi|16554629 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 48.5 bits (114), Expect = 1e-04 Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 11/177 (6%) Query: 2794 RPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHS 2852 +P + F AG+ + V+ + F+ G + + + IW A + K + H Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG----AYDGKFEKTISGHK 87 Query: 2853 KATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQ 2912 SD A+ + S+L+ ++ +D++ + +WD +S G L H + + P+ Sbjct: 88 LGISDVAWSSDSNLLVSA---SDDKTLKIWD--VSSGKCL-KTLKGHSNYVFCCNFNPQS 141 Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 L++SG V I+D++ + + T AH + A+ + + S +G ++W Sbjct: 142 NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198 >gi|16554627 WD repeat domain 5 [Homo sapiens] Length = 334 Score = 48.5 bits (114), Expect = 1e-04 Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 11/177 (6%) Query: 2794 RPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHS 2852 +P + F AG+ + V+ + F+ G + + + IW A + K + H Sbjct: 32 KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG----AYDGKFEKTISGHK 87 Query: 2853 KATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQ 2912 SD A+ + S+L+ ++ +D++ + +WD +S G L H + + P+ Sbjct: 88 LGISDVAWSSDSNLLVSA---SDDKTLKIWD--VSSGKCL-KTLKGHSNYVFCCNFNPQS 141 Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969 L++SG V I+D++ + + T AH + A+ + + S +G ++W Sbjct: 142 NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198 >gi|5803221 WD repeat-containing protein 3 [Homo sapiens] Length = 943 Score = 48.5 bits (114), Expect = 1e-04 Identities = 45/226 (19%), Positives = 94/226 (41%), Gaps = 12/226 (5%) Query: 2769 MTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKC-GVADGE 2827 M+ P + ++TG D SV+ +++ + ++ + + TR + C + + Sbjct: 502 MSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQ 561 Query: 2828 GFLSIWQVNQTAS-----NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLW 2882 L++ ++ T K ++S H +L+AT + +RNV +W Sbjct: 562 KLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG---SADRNVKIW 618 Query: 2883 DTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHD 2942 + + HD LQ+ PK L + G+ + +D + + I T + H Sbjct: 619 GLDFGDCHKSLFA---HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHH 675 Query: 2943 SAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQS 2988 I LA+ P +Y + S + ++++W T LI + E +++ Sbjct: 676 QEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREA 721 Score = 47.0 bits (110), Expect = 3e-04 Identities = 18/62 (29%), Positives = 36/62 (58%) Query: 2908 YAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIK 2967 + P + ++ G + G + ++D+ L+ T AHD A+ +++L P + F TG A+ ++K Sbjct: 462 FVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVK 521 Query: 2968 VW 2969 W Sbjct: 522 FW 523 Score = 40.0 bits (92), Expect = 0.035 Identities = 51/258 (19%), Positives = 99/258 (38%), Gaps = 23/258 (8%) Query: 2789 MFEWT-RPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMS 2847 +F W R + + Q VT L + G V +G + I+ + N ++ Sbjct: 47 VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGN----VT 102 Query: 2848 WQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQ 2907 + H A + + +A+ D + +WD + G + G H T Sbjct: 103 FNGHKAAITTLKYDQLGGRLASGSKDTD---IIVWDVINESGLYRLKG---HKDAITQAL 156 Query: 2908 YAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIK 2967 + ++ LL++ G+ V +D+ + T H + + L L E+ TG+++ ++ Sbjct: 157 FLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELR 216 Query: 2968 VWRLTGHGLIHSFKSEHAKQSIFRNIGA--------GVMQIDIIQGNRLFSCGADGTL-- 3017 VW + I + K+ + G G + D +R+ SC G++ Sbjct: 217 VWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMR 276 Query: 3018 --KTRVLPNAFNIPNRIL 3033 + RV+ A + RIL Sbjct: 277 EGRDRVVNLAVDKTGRIL 294 >gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens] Length = 400 Score = 47.8 bits (112), Expect = 2e-04 Identities = 43/206 (20%), Positives = 81/206 (39%), Gaps = 21/206 (10%) Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873 FN + + + G +S + +++ + P ++Q H + F+ V ++G Sbjct: 76 FNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQD 135 Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933 C S + G+ A+ LQ+ + + + G G V I + Q Sbjct: 136 KQFAWHC------SESGQRLGGYRT-SAVASGLQFDVETRHVFIGDHSGQVTILKLEQEN 188 Query: 2934 --LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGH-GLIHSFKSEHAKQSIF 2990 L+ TF+ H + AL DP + +GS++ ++ +W + G G + + + Sbjct: 189 CTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDR---- 244 Query: 2991 RNIGAGVMQIDIIQGNR-LFSCGADG 3015 V + Q R L SCG DG Sbjct: 245 ------VQALSYAQHTRQLISCGGDG 264 Score = 40.0 bits (92), Expect = 0.035 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 26/178 (14%) Query: 2803 QAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFIT 2862 QA +RVT + F V + E LS Q Q A W C S++ Sbjct: 111 QAHQSRVTMILF--------VLELEWVLSTGQDKQFA--------WHC-SESGQRLGGYR 153 Query: 2863 SSSLVATSGHSNDNRNVCLWD--------TLISPGNSLIHGFTCHDHGATVLQYAPKQQL 2914 +S++ + + R+V + D L +L+ F H G T L + P Q++ Sbjct: 154 TSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRV 213 Query: 2915 LISGGRKGHVCIFDIRQRQ-LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRL 2971 L SG V ++DI R+ Q H+ ++AL+ + + +G I VW + Sbjct: 214 LFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNM 271 >gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] Length = 446 Score = 47.0 bits (110), Expect = 3e-04 Identities = 33/144 (22%), Positives = 70/144 (48%), Gaps = 15/144 (10%) Query: 2833 WQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNS- 2891 W V+Q +P++ H+++ D + + + V S + + ++ +WD +P + Sbjct: 250 WHVDQ-----RPFVG---HTRSVEDLQWSPTENTVFAS--CSADASIRIWDIRAAPSKAC 299 Query: 2892 LIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQL---IHTFQAHDSAIKAL 2948 ++ T HD V+ ++ ++ L+SGG G + I+D+RQ + + TF+ H + + ++ Sbjct: 300 MLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSV 359 Query: 2949 ALDPYEE-YFTTGSAEGNIKVWRL 2971 P + F A+ I W L Sbjct: 360 EWHPQDSGVFAASGADHQITQWDL 383 >gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [Homo sapiens] Length = 340 Score = 46.6 bits (109), Expect = 4e-04 Identities = 49/236 (20%), Positives = 89/236 (37%), Gaps = 16/236 (6%) Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838 ++ +QDG + +++ ++ + +T Y S GN + SI+ + Sbjct: 71 VSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTR 129 Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898 N + H+ S F+ S +V +SG + LWD + + FT Sbjct: 130 EGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTT----CALWDIETAQQTTT---FTG 182 Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958 H L +P + +SG ++DIR +F H S I A++ P F Sbjct: 183 HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFA 242 Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014 TGS + +++ L + + + NI G+ + + RL G D Sbjct: 243 TGSDDATCRLFDLRADQELLLYSHD--------NIICGITSVAFSKSGRLLLAGYD 290 >gi|5729852 guanine nucleotide-binding protein, beta-5 subunit isoform a [Homo sapiens] Length = 353 Score = 46.6 bits (109), Expect = 4e-04 Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 20/166 (12%) Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVL--QY 2908 H+ S +F S + T+ + + LWD L+ F H HGA VL Sbjct: 152 HTNYLSACSFTNSDMQILTA---SGDGTCALWDV---ESGQLLQSF--HGHGADVLCLDL 203 Query: 2909 APKQ--QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNI 2966 AP + +SGG ++D+R Q + F+ H+S I ++ P + F +GS + Sbjct: 204 APSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATC 263 Query: 2967 KVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCG 3012 +++ L + + E +I G +D RL G Sbjct: 264 RLYDLRADREVAIYSKE--------SIIFGASSVDFSLSGRLLFAG 301 >gi|20336270 guanine nucleotide-binding protein, beta-5 subunit isoform b [Homo sapiens] Length = 395 Score = 46.6 bits (109), Expect = 4e-04 Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 20/166 (12%) Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVL--QY 2908 H+ S +F S + T+ + + LWD L+ F H HGA VL Sbjct: 194 HTNYLSACSFTNSDMQILTA---SGDGTCALWDV---ESGQLLQSF--HGHGADVLCLDL 245 Query: 2909 APKQ--QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNI 2966 AP + +SGG ++D+R Q + F+ H+S I ++ P + F +GS + Sbjct: 246 APSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATC 305 Query: 2967 KVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCG 3012 +++ L + + E +I G +D RL G Sbjct: 306 RLYDLRADREVAIYSKE--------SIIFGASSVDFSLSGRLLFAG 343 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 120,907,916 Number of Sequences: 37866 Number of extensions: 5627969 Number of successful extensions: 20043 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 97 Number of HSP's successfully gapped in prelim test: 157 Number of HSP's that attempted gapping in prelim test: 18626 Number of HSP's gapped (non-prelim): 1419 length of query: 3036 length of database: 18,247,518 effective HSP length: 120 effective length of query: 2916 effective length of database: 13,703,598 effective search space: 39959691768 effective search space used: 39959691768 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.