Guide to the Human Genome
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Search of human proteins with 119120894

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|119120894 Dmx-like 2 [Homo sapiens]
         (3036 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|119120894 Dmx-like 2 [Homo sapiens]                               6159   0.0  
gi|148528998 Dmx-like 1 [Homo sapiens]                               3245   0.0  
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]             64   2e-09
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]             64   2e-09
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]             64   2e-09
gi|19913369 transducin beta-like 3 [Homo sapiens]                      59   6e-08
gi|26665869 WD repeat domain 51B [Homo sapiens]                        56   5e-07
gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [...    56   6e-07
gi|83779014 katanin p80 subunit B 1 [Homo sapiens]                     55   8e-07
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [...    55   8e-07
gi|223005862 echinoderm microtubule associated protein like 6 [H...    54   3e-06
gi|21536371 telomerase-associated protein 1 [Homo sapiens]             53   5e-06
gi|13376840 WD repeat domain 61 [Homo sapiens]                         52   7e-06
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]    52   1e-05
gi|21071067 TBP-associated factor 5 [Homo sapiens]                     51   2e-05
gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [H...    51   2e-05
gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]              51   2e-05
gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]              51   2e-05
gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]              51   2e-05
gi|197927448 WD repeat domain 6 protein [Homo sapiens]                 50   4e-05
gi|221219020 NYD-SP11 protein [Homo sapiens]                           49   8e-05
gi|5174447 guanine nucleotide binding protein (G protein), beta ...    49   8e-05
gi|16554629 WD repeat domain 5 [Homo sapiens]                          49   1e-04
gi|16554627 WD repeat domain 5 [Homo sapiens]                          49   1e-04
gi|5803221 WD repeat-containing protein 3 [Homo sapiens]               49   1e-04
gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]      48   2e-04
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]      47   3e-04
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [...    47   4e-04
gi|5729852 guanine nucleotide-binding protein, beta-5 subunit is...    47   4e-04
gi|20336270 guanine nucleotide-binding protein, beta-5 subunit i...    47   4e-04

>gi|119120894 Dmx-like 2 [Homo sapiens]
          Length = 3036

 Score = 6159 bits (15978), Expect = 0.0
 Identities = 3036/3036 (100%), Positives = 3036/3036 (100%)

Query: 1    MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60
            MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV
Sbjct: 1    MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60

Query: 61   SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120
            SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP
Sbjct: 61   SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120

Query: 121  QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180
            QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD
Sbjct: 121  QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180

Query: 181  GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240
            GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW
Sbjct: 181  GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240

Query: 241  RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR 300
            RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR
Sbjct: 241  RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSIASSLSHAGR 300

Query: 301  HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI 360
            HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI
Sbjct: 301  HKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHFHI 360

Query: 361  AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD 420
            AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD
Sbjct: 361  AASINPATDIPNVLVGTAFNVDDGNGGFVVHWLNNKEFHFTSSTEVFMHQLRKLSDKQVD 420

Query: 421  HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL 480
            HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL
Sbjct: 421  HENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPRTYSRL 480

Query: 481  SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV 540
            SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV
Sbjct: 481  SVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIFRQVQV 540

Query: 541  SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS 600
            SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS
Sbjct: 541  SFSSRIPVAFPSGDASSLSKNIMMYACINATKDSHHTLLHQEGMSVGSPHGSQPHSRSHS 600

Query: 601  THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS 660
            THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS
Sbjct: 601  THMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCGHRFHLNDLACHS 660

Query: 661  VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA 720
            VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA
Sbjct: 661  VLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLRNAATRTFHDPNA 720

Query: 721  IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA 780
            IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA
Sbjct: 721  IYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPSYCLGTYCNSASA 780

Query: 781  CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT 840
            CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT
Sbjct: 781  CFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTARPGCIIELDAIT 840

Query: 841  NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD 900
            NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD
Sbjct: 841  NQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKETEIFFQPSQGYRPPPFSEKFFLVVIEKD 900

Query: 901  SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS 960
            SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS
Sbjct: 901  SNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPETSPSVSPMPHSSS 960

Query: 961  IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS 1020
            IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS
Sbjct: 961  IANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYPVCLAPYLVVTTCS 1020

Query: 1021 DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG 1080
            DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG
Sbjct: 1021 DNKVRFWKCCMEANPECNKSDEKEIYHWKRWPLMNDEGEDNSSTVSIVGRPVAVSCSYTG 1080

Query: 1081 RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS 1140
            RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS
Sbjct: 1081 RLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHLDDLVKVGSVLDSRVS 1140

Query: 1141 VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI 1200
            VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI
Sbjct: 1141 VDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTVGVGANIFMYGRLSGI 1200

Query: 1201 VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL 1260
            VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL
Sbjct: 1201 VTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGTPSLPVSLSWVRDGIL 1260

Query: 1261 VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD 1320
            VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD
Sbjct: 1261 VVGMDCEMHVYAQWKHAVKFGDTEADSSNAEEAAMQDHSTFKSNMLARKSVVEGTAISDD 1320

Query: 1321 VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA 1380
            VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA
Sbjct: 1321 VFCSPTVIQDGGLFEAAHVLSPTLPQYHPTQLLELMDLGKVRRAKAILSHLVKCIAGEVA 1380

Query: 1381 IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD 1440
            IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD
Sbjct: 1381 IVRDPDAGEGTKRHLSRTISVSGSTAKETVTVGKDGTRDYTEIDSIPPLPLYALLAADQD 1440

Query: 1441 TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ 1500
            TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ
Sbjct: 1441 TSYRISEESTKIPQSYEDQTVSQPEDQYSELFQIQDIPTDDIDLEPEKRENKSKVINLSQ 1500

Query: 1501 YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD 1560
            YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD
Sbjct: 1501 YGPAYFGQEHARVLSSHLMHSSLPGLTRLEQMFLVALADTVATTSTELDESRDKSCSGRD 1560

Query: 1561 TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI 1620
            TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI
Sbjct: 1561 TLDECGLRYLLAMRLHTCLLTSLPPLYRVQLLHQGVSTCHFAWAFHSEAEEELINMIPAI 1620

Query: 1621 QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW 1680
            QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW
Sbjct: 1621 QRGDPQWSELRAMGIGWWVRNINTLRRCIEKVAKASFQRNNDALDAALFYLSMKKKAVVW 1680

Query: 1681 GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV 1740
            GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV
Sbjct: 1681 GLFRSQHDEKMTTFFSHNFNEDRWRKAALKNAFSLLGKQRFEQSAAFFLLAGSLKDAIEV 1740

Query: 1741 CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL 1800
            CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL
Sbjct: 1741 CLEKMEDIQLAMVIARLYESEFETSSTYISILNQKILGCQKDGSGFSCKRLHPDPFLRSL 1800

Query: 1801 AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG 1860
            AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG
Sbjct: 1801 AYWVMKDYTRALDTLLEQTPKEDDEHQVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEG 1860

Query: 1861 TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK 1920
            TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK
Sbjct: 1861 TLATLGLKTEKNFVDKINLIERKLFFTTANAHFKVGCPVLALEVLSKIPKVTKTSALSAK 1920

Query: 1921 KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE 1980
            KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE
Sbjct: 1921 KDQPDFISHRMDDVPSHSKALSDGNGSSGIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGE 1980

Query: 1981 DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE 2040
            DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE
Sbjct: 1981 DHDSALDEEEDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAE 2040

Query: 2041 QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK 2100
            QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK
Sbjct: 2041 QLKFRACLKILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSK 2100

Query: 2101 TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS 2160
            TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS
Sbjct: 2101 TYSKVESDLLDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLS 2160

Query: 2161 YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA 2220
            YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA
Sbjct: 2161 YCSLHGAQGGGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIA 2220

Query: 2221 NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT 2280
            NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT
Sbjct: 2221 NPVLYLNNHIHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQT 2280

Query: 2281 EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL 2340
            EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL
Sbjct: 2281 EGNQFTGMAYQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKL 2340

Query: 2341 NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE 2400
            NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE
Sbjct: 2341 NILLCEAVVAVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSE 2400

Query: 2401 NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF 2460
            NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF
Sbjct: 2401 NISAPPVLSEDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYF 2460

Query: 2461 VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH 2520
            VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH
Sbjct: 2461 VAKPFLPLSDSGVIYDSDESIHSDEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALH 2520

Query: 2521 NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS 2580
            NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS
Sbjct: 2521 NVKNFFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLS 2580

Query: 2581 VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS 2640
            VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS
Sbjct: 2581 VGAGPAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQS 2640

Query: 2641 EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW 2700
            EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW
Sbjct: 2641 EVEADLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIW 2700

Query: 2701 IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK 2760
            IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK
Sbjct: 2701 IGEEYDRESKSSDDVDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMK 2760

Query: 2761 RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK 2820
            RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK
Sbjct: 2761 RNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNK 2820

Query: 2821 CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC 2880
            CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC
Sbjct: 2821 CGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVC 2880

Query: 2881 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA 2940
            LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA
Sbjct: 2881 LWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA 2940

Query: 2941 HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI 3000
            HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI
Sbjct: 2941 HDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQI 3000

Query: 3001 DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL 3036
            DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL
Sbjct: 3001 DIIQGNRLFSCGADGTLKTRVLPNAFNIPNRILDIL 3036


>gi|148528998 Dmx-like 1 [Homo sapiens]
          Length = 3027

 Score = 3245 bits (8413), Expect = 0.0
 Identities = 1708/3097 (55%), Positives = 2155/3097 (69%), Gaps = 142/3097 (4%)

Query: 1    MHLHQVLTGAVNPGDNCYSVGSVGDVPFTAYGSGCDIVILANDFECVQIIPGAKHGNIQV 60
            M+LHQVLTGAVNPGD+C+SVGS+GD  FTAY SGCDIVIL +DFE +QIIPGAKHGNIQV
Sbjct: 1    MNLHQVLTGAVNPGDHCFSVGSIGDQRFTAYASGCDIVILGSDFERLQIIPGAKHGNIQV 60

Query: 61   SCVECSNQQGRIAASYGNAVCIFEPLGINSHKRNCQLKCQWLKTGQFFLSSVTYNLAWDP 120
             CV+CS QQG+IAASYGN + IFEP+ +   K+N +L  QW K+GQFFL S+ +N+ WDP
Sbjct: 61   GCVDCSMQQGKIAASYGNVISIFEPVNLPKQKKNLELYSQWQKSGQFFLESIAHNITWDP 120

Query: 121  QDNRLLTATDSIQLWAPPGDDILEEEEEIDNTVPPVLNDWKCVWQCKTSVSVHLMEWSPD 180
              +RLLT +  +QLW+    +   E+E ++ T      DWKC+W CKT+  VHLM++SPD
Sbjct: 121  TGSRLLTGSSYLQLWSNTNLEKPTEDENLNKT-DLNFGDWKCIWHCKTASQVHLMKFSPD 179

Query: 181  GEYFATAGKDDCLLKVWYPMTGWKSSIIPQDHHEVKRRQSSTQFSFVYLAHPRAVTGFSW 240
            GE+FATAGKDDCLLKVWY +  W++++   D    K+ Q    FSFVYLAHPRAV GFSW
Sbjct: 180  GEFFATAGKDDCLLKVWYNVENWRTAVTSPDGSSEKQSQGEIDFSFVYLAHPRAVNGFSW 239

Query: 241  RKTSKYMPRGSVCNVLLTSCHDGVCRLWAETLLPEDCLLGEQICETTTSSI--ASSLSHA 298
            RKTSKYMPR SVCNVLLT C D VCRLW ET LP DCLL    C   T SI   ++    
Sbjct: 240  RKTSKYMPRASVCNVLLTCCKDNVCRLWVETFLPNDCLLYGGDCSHWTESINLTNNFKRN 299

Query: 299  GRHKDRIQHALETIHHLKNLRKGQRRSSVLVTHAELMPDQTAMHEVQRHISHHANALCHF 358
               K+R+Q+ALE   +L++ R+G+RRS  LV H   +P Q   H V R+   HANALCHF
Sbjct: 300  ASSKERVQNALEV--NLRHFRRGRRRSLALVAHTGYLPHQQDPHHVHRNTPLHANALCHF 357

Query: 359  HIAASINPATDIPNVLVGTAFNVDDGN---GGFVVHWLNNKEFHFTSSTEVFMHQLRKLS 415
            HIAASINPATDIP +   T+ ++++     G FVVHWLNNKE HFT S EVF+ QLRK  
Sbjct: 358  HIAASINPATDIPLLPSITSLSLNENEEKTGPFVVHWLNNKELHFTLSMEVFLQQLRK-- 415

Query: 416  DKQVDHENDDADREDEEHSQEDRERGLHMKLDHDLSLDRESEAGTGSSEHEDGEREGSPR 475
                       ++   E S ED  +        D+  D E++ G    +    ++E    
Sbjct: 416  ---------SFEQPSSEASVEDSNQA-------DVKSDEETDDGVDDLKINPEKKELGCD 459

Query: 476  TYSRLSVPMPLPTVLLDRKIETLLTEWNKNPDMLFTIHPVDGTFLVWHVKYLDEYNPGIF 535
                 S    L +  +D +IE LL+EW+KN DMLF+IHP+DG+ LVWHV +LDEY PG+F
Sbjct: 460  KMVPNSSFTSLSSAAIDHQIEVLLSEWSKNADMLFSIHPMDGSLLVWHVDWLDEYQPGMF 519

Query: 536  RQVQVSFSSRIPVAFPSGDASSLSKNIMMYAC-------INATKDSHHTLLHQEGMSVGS 588
            RQVQVSF SRIPVAFP+GDA+SL K+IMMYAC       I   K     L     M + S
Sbjct: 520  RQVQVSFVSRIPVAFPTGDANSLCKSIMMYACTKNVDLAIQQGKQKPSGLTRSTSMLISS 579

Query: 589  PHGSQPHSRSHSTHMNILAPTVMMISKHIDGSLNQWAVTFADKSAFTTVLTVSHKFRYCG 648
             H       S+S  ++I  P VMMISKH DGSLNQW V+FA++SAF+TVL++SHK RYCG
Sbjct: 580  GHNKS----SNSLKLSIFTPNVMMISKHADGSLNQWLVSFAEESAFSTVLSISHKSRYCG 635

Query: 649  HRFHLNDLACHSVLPLLLTSSHHNALLTPELDCQWDSDNKLSRLMDPVKHIKGSSKQPLR 708
            HRFHLNDLACHSVLPLLLT+SHHNAL TP++D          +  D +   + S  Q  +
Sbjct: 636  HRFHLNDLACHSVLPLLLTTSHHNALRTPDVD-------NPEQPFDALNIEECSLTQQNK 688

Query: 709  NAATRTFHDPNAIYSELILWRVDPIGPLSYTGGVSELARINSLHTSAFSNVAWLPTLIPS 768
            +     F DP+A+YSELILWRVDP+GPLS++GGVSELARINSLH SAFSNVAWLPTLIPS
Sbjct: 689  STVDVAFQDPSAVYSELILWRVDPVGPLSFSGGVSELARINSLHVSAFSNVAWLPTLIPS 748

Query: 769  YCLGTYCNSASACFVASDGKNLRLYQAVVDARKLLDELSDPESSKLIGEVFNIVSQQSTA 828
            YCLG YCNS SACFVASDG+ LRLY+AV+DA+KLL ELS+PE SK +GEVFNIVSQQSTA
Sbjct: 749  YCLGAYCNSPSACFVASDGQYLRLYEAVIDAKKLLSELSNPEISKYVGEVFNIVSQQSTA 808

Query: 829  RPGCIIELDAITNQCGSNTQLLHVFQEDFIIGYKPHKEDMEKKET-EIFFQPSQGYRPPP 887
            RPGCII LD IT   G  TQLLHVF+EDFI+       ++EKK   +     + G  P  
Sbjct: 809  RPGCIIALDPITKLHGRKTQLLHVFEEDFILN------NLEKKSLGKDSILSNAGSSPNG 862

Query: 888  FSEKFFLVVIEKDSNNNSILHMWHLHLKSVQACLAKASEGASSESLLSVPGQKNVDSSPE 947
            FSEKF+L+VIE   +N S+LHMW+LHLKS+   L +  +   SE++     +++  SSPE
Sbjct: 863  FSEKFYLIVIECTQDNRSLLHMWNLHLKSIPVSLDEKVDTKLSEAVWQP--EEHYSSSPE 920

Query: 948  TSPSVSPMPHSSSIANLQTASKLILSSRLVYSQPLDLPESVEVIRATPSAGHLSSSSIYP 1007
               S     + +  ANLQ+ S+L L S +VYSQ L LPE VE+I   PSAGHLSSSSIYP
Sbjct: 921  KILSPFSQKYQACRANLQSTSRLTLFSEMVYSQELHLPEGVEIISIKPSAGHLSSSSIYP 980

Query: 1008 VCLAPYLVVTTCSDNKVRFWKCCMEANPECNKSDEKE--IYHWKRWPLMNDEGEDNSSTV 1065
             C APYL+ T+CSD KVRFW+C +         + K    Y W+ WPL+ ++G  ++S++
Sbjct: 981  ACSAPYLLATSCSDEKVRFWRCRVTDGESATSKNGKIDLAYIWEEWPLLIEDGLQSNSSI 1040

Query: 1066 SIVGRPVAVSCSYTGRLAVAYKQPIHHNGFVSKEFSMHVCIFECESTGGSEWVLEQTIHL 1125
            ++ GRPV VSC++T RLAVAYKQP   N   S++F MHV IFECESTGGS WVLEQTIHL
Sbjct: 1041 TVPGRPVEVSCAHTNRLAVAYKQPAS-NSRSSQDFVMHVSIFECESTGGSCWVLEQTIHL 1099

Query: 1126 DDLVKVGSVLDSRVSVDSNLFVYSKSDALLSKDRYLIPNIKHLVHLDWVSKEDGSHILTV 1185
            D+L    +VLDS +SVDSNL  Y+K D  LS    +  N KHLVHLDW+S+EDGSHILTV
Sbjct: 1100 DEL---STVLDSGISVDSNLVAYNKQDMYLSSKENITSNTKHLVHLDWMSREDGSHILTV 1156

Query: 1186 GVGANIFMYGRLSGIVTEQTNSKDGVAVITLPLGGSIKQGVKSRWVLLRSIDLVSSVDGT 1245
            G+G+ +FMYG L+G V +QT    G   +  PL  S K    S++VLLRS+DLVSSVDG+
Sbjct: 1157 GIGSKLFMYGPLAGKVQDQT----GKETLAFPLWESTKVVPLSKFVLLRSVDLVSSVDGS 1212

Query: 1246 PSLPVSLSWVRDGILVVGMDCEMHVYAQWKHAVKFGDTEADS--------------SNAE 1291
            P  PVSLSWVRDGILVVGMDCEMHVY QW+ + K      DS              SN+ 
Sbjct: 1213 PPFPVSLSWVRDGILVVGMDCEMHVYCQWQPSSKQEPVITDSYSGSTPSITSLIKQSNSS 1272

Query: 1292 EAAMQDHSTFKSNM--LARKSVVEGTAISDDVFCSPTVIQDGGLFEAAHVLSPTLPQYHP 1349
                    T   +M  LA+K   + TA    V      ++D GLFEAAHVLSPTLPQYHP
Sbjct: 1273 SGLHPPKKTLTRSMTSLAQKICGKKTAFDPSVD-----MEDSGLFEAAHVLSPTLPQYHP 1327

Query: 1350 TQLLELMDLGKVRRAKAILSHLVKCIAGEVAIVRDPDAGEGTKRHLSRTISVSGSTAKET 1409
             QLLELMDLGKVRRAKAILSHLVKCIAGEV  + + ++    +R  S TIS SGST ++ 
Sbjct: 1328 LQLLELMDLGKVRRAKAILSHLVKCIAGEVVALNEAESNH-ERRLRSLTISASGSTTRDP 1386

Query: 1410 VTVGKDGTRDYTEIDSIPPLPLYALLAADQDTSYRISEESTKIPQSYEDQTVSQPEDQYS 1469
                K    DYTEIDS+PPLPLYALLAAD D+ Y   E+S+   +S   ++    ++ Y 
Sbjct: 1387 QAFNKAENTDYTEIDSVPPLPLYALLAADDDSCYSSLEKSSN--ESTLSKSNQLSKESYD 1444

Query: 1470 ELFQIQDIPTDDIDLEPEKRENKSKVINLSQYGPAYFGQEHARVLSSHLMHSSLPGLTRL 1529
            ELFQ Q + TD   LE ++   K +VI+LSQY P YFG EHA+VLS HL+HSSLPGL+R+
Sbjct: 1445 ELFQTQLLMTDTHMLETDEENTKPRVIDLSQYSPTYFGPEHAQVLSGHLLHSSLPGLSRM 1504

Query: 1530 EQMFLVALADTVATTSTELDESRDKSCSGRDTLDECGLRYLLAMRLHTCLLTSLPPLYRV 1589
            EQM L+ALADT+ATTST++ ESRD+S  G +TLDECGL++LLA+RLHT L TSLP  YR 
Sbjct: 1505 EQMSLMALADTIATTSTDIGESRDRS-QGGETLDECGLKFLLAVRLHTFLTTSLPA-YRA 1562

Query: 1590 QLLHQGVSTCHFAWAFHSEAEEELINMIPAIQRGDPQWSELRAMGIGWWVRNINTLRRCI 1649
            QLLHQG+ST HFAWAFHS AEEEL+NM+PA+Q+ DP WSELRAMG+GWWVRN   LR+CI
Sbjct: 1563 QLLHQGLSTSHFAWAFHSVAEEELLNMLPAMQKDDPTWSELRAMGVGWWVRNTRILRKCI 1622

Query: 1650 EKVAKASFQRNNDALDAALFYLSMKKKAVVWGLFRSQHDEKMTTFFSHNFNEDRWRKAAL 1709
            EKVAKA+F R ND LDAA+FYL+MKKKAV+WGL+R++ + +MT FF HNF ++RWRKAAL
Sbjct: 1623 EKVAKAAFYRKNDPLDAAIFYLAMKKKAVIWGLYRAEKNTRMTQFFGHNFEDERWRKAAL 1682

Query: 1710 KNAFSLLGKQRFEQSAAFFLLAGSLKDAIEVCLEKMEDIQLAMVIARLYESEFETSSTYI 1769
            KNAFSLLGKQRFE SAAFFLLAG L+DAIEVCLEK+ DIQLA+VIARLYESEF+TS+ Y 
Sbjct: 1683 KNAFSLLGKQRFEHSAAFFLLAGCLRDAIEVCLEKLNDIQLALVIARLYESEFDTSAAYK 1742

Query: 1770 SILNQKILGCQKDGSGFSCK---RLHPDPFLRSLAYWVMKDYTRALDTLLEQTPKEDDEH 1826
            SIL +K+LG     S   C     +H DPFLRS+AYW+++DY+ AL+TL++Q  +E+D+ 
Sbjct: 1743 SILRKKVLGIDSPVSEL-CSLNINMHHDPFLRSMAYWILEDYSGALETLIKQPIRENDDQ 1801

Query: 1827 QVIIKSCNPVAFSFYNYLRTHPLLIRRNLASPEGTLATLGLKTEKNFVDKINLIERKLFF 1886
              ++ + NP  F+FYNYLRTHPLL+RR+  S +     + L  +      INL ER+LFF
Sbjct: 1802 --VLSASNPTVFNFYNYLRTHPLLLRRHFGSSDTFSTHMSLTGKSGLAGTINLSERRLFF 1859

Query: 1887 TTANAHFKVGCPVLALEVLSKIPKVTK--------TSALSAKKD----QPDFISHRMD-- 1932
            TTA+AH K GCP+LALEVLSK+PKV K        +S L   KD     P  +  R D  
Sbjct: 1860 TTASAHLKAGCPMLALEVLSKMPKVIKKTRPFYRASSFLDTSKDCSPSSPLKLDAREDKS 1919

Query: 1933 DVPSHSKALSDGNGSS---GIEWSNVTSSQYDWSQPIVKVDEEPLNLDWGEDHDSALDEE 1989
                 S++L +G GSS     E  + ++  +DWSQP V   ++ L L W  D+D   +E 
Sbjct: 1920 SAVDWSQSLINGFGSSSEGSSEKQSNSTLSFDWSQPSVVFQDDSLELKWDSDND---EEN 1976

Query: 1990 EDDAVGLVMKSTDAREKDKQSDQKASDPNMLLTPQEEDDPEGDTEVDVIAEQLKFRACLK 2049
            ED  + +       R+ DK+ D  +S+     +  +E+D    +E D+IA QLKFRACLK
Sbjct: 1977 EDVPISMKELKPLQRKTDKKLDDISSNYTESFSTLDENDLLNPSE-DIIAVQLKFRACLK 2035

Query: 2050 ILMTELRTLATGYEVDGGKLRFQLYNWLEKEIAALHEICNHESVIKEYSSKTYSKVESDL 2109
            IL  ELRTL+TGYE+DGGKLR+QLY+WLEKE+ AL   C+  S  +E  S  + + E + 
Sbjct: 2036 ILTVELRTLSTGYEIDGGKLRYQLYHWLEKEVIALQRTCDFCSDAEELQS-AFGRNEDEF 2094

Query: 2110 LDQEEMVDKPDIGSYERHQIERRRLQAKREHAERRKSWLQKNQDLLRVFLSYCSLHGAQG 2169
               E+  D P       HQ + ++L   RE+ + ++ WL K Q LLR+FLSYC LHG+ G
Sbjct: 2095 GLNEDAEDLP-------HQTKVKQL---RENFQEKRQWLLKYQSLLRMFLSYCILHGSHG 2144

Query: 2170 GGLASVRMELKFLLQESQQETTVKQLQSPLPLPTTLPLLSASIASTKTVIANPVLYLNNH 2229
            GGLASVRMEL  LLQESQQET+     SPL   T++PLL A  A+ KTV+ANP+L+L+N 
Sbjct: 2145 GGLASVRMELILLLQESQQETSEPLFSSPLSEQTSVPLLFACTANAKTVVANPLLHLSNL 2204

Query: 2230 IHDILYTIVQMKTPPHPSIEDVKVHTLHSLAASLSASIYQALCDSHSYSQTEGNQFTGMA 2289
             HDIL+ I+   +PPHP I+  KV+ +H+LAASLSA IYQ LC SH+YS  + NQFTGM 
Sbjct: 2205 THDILHAIINFDSPPHPDIQSNKVYVMHTLAASLSACIYQCLCGSHNYSSFQTNQFTGMV 2264

Query: 2290 YQGLLLSDRRRLRTESIEEHATPNSSPAQWPGVSSLINLLSSAQDEDQPKLNILLCEAVV 2349
            YQ +LL  R  L+T S++E  TPN+SPAQWPG++ LI LL+S+ +E Q  L +LLCE + 
Sbjct: 2265 YQTVLLPHRPSLKTGSLDEALTPNTSPAQWPGITCLIRLLNSSGEEAQSGLTVLLCEILT 2324

Query: 2350 AVYLSLLIHALATNSSSELFRLAAHPLNNRMWAAVFGGGVKLVVKPRRQSENISAPPVLS 2409
            AVYLSL IH LAT+SS+ELFR+ AHPLN +MW+AVFGGG  +  K +  S+ +    ++ 
Sbjct: 2325 AVYLSLFIHGLATHSSNELFRIVAHPLNEKMWSAVFGGGAHVPSKEQTHSKTLPVSSLVE 2384

Query: 2410 EDIDKHRRRFNMRMLVPGRPVKDATPPPVPAERPSYKEKFIPPELSMWDYFVAKPFLPLS 2469
            E   +++R    +M          +  PV  E  + KEKFIPPELS+WDYF+AKPFLP S
Sbjct: 2385 EGEKQNKRFRPSKMSCRESAPLTPSSAPVSQESLAVKEKFIPPELSIWDYFIAKPFLPSS 2444

Query: 2470 DSGVIYDSDESIHS-----DEEDDAFFSDTQIQEHQDPNSYSWALLHLTMVKLALHNVKN 2524
             S   YDS+ES+ S     D++DD   SD  +QEH + NSYSW+L+ L MV+L L+N+K 
Sbjct: 2445 QSRAEYDSEESLGSDDDDNDDDDDVLASDFHLQEHSNSNSYSWSLMRLAMVQLVLNNLKT 2504

Query: 2525 FFPIAGLEFSELPVTSPLGIAVIKNLENWEQILQEKMDQFEGPPPNYINTYPTDLSVGAG 2584
            F+P AG + +ELPV+SPL  AV+K L+ WEQ+L  +++   GPP NYI ++  + S+ AG
Sbjct: 2505 FYPFAGHDLAELPVSSPLCHAVLKTLQCWEQVLLRRLEIHGGPPQNYIASHTAEESLSAG 2564

Query: 2585 PAILRNKAMLEPENTPFKSRDSSAFPVKRLWHFLVKQEVLQETFIRYIFTKKRKQSEVEA 2644
            PAILR+KA+LEP NTPFKS+   A  VKRLW +LVKQE +QETFI+ IFTKKR  +E+EA
Sbjct: 2565 PAILRHKALLEPTNTPFKSKHHLALSVKRLWQYLVKQEEIQETFIKNIFTKKRCLNEIEA 2624

Query: 2645 DLGYPGGKAKVIHKESDMIMAFSVNKANCNEIVLASTHDVQELDVTSLLACQSYIWIGEE 2704
            DLGYPGGKA++IHKESD+I AF+VNKAN N I +AS+HDVQELDV+ +LA Q Y W+ ++
Sbjct: 2625 DLGYPGGKARIIHKESDIITAFAVNKANRNCIAIASSHDVQELDVSGILATQVYTWVDDD 2684

Query: 2705 YDRESKSSDD---VDYRGSTTTLYQPSATSYSASQVHPPSSLPWLGTGQTSTGASVLMKR 2761
             + E+K S+D   +  R   T +     T Y+ S    P ++PWLG+ QT  GASV++K+
Sbjct: 2685 IEVETKGSEDFLVIHARDDLTAV--QGTTPYTHSNPGTPINMPWLGSTQTGRGASVMIKK 2742

Query: 2762 NLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKC 2821
             ++NV+RMTSHP   YYLTGAQDGSVRMFEW   QQ+ CFR  GN+RVTR+ FN QGNK 
Sbjct: 2743 AINNVRRMTSHPTLPYYLTGAQDGSVRMFEWGHSQQITCFRSGGNSRVTRMRFNYQGNKF 2802

Query: 2822 GVADGEGFLSIWQVN-----QTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDN 2876
            G+ D +G+LS++Q N      T S PKPY++WQCH+K  +DF F++SSSL+AT+G S DN
Sbjct: 2803 GIVDADGYLSLYQTNWKCCPVTGSMPKPYLTWQCHNKTANDFVFVSSSSLIATAGLSTDN 2862

Query: 2877 RNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIH 2936
            RNVCLWDTL++P NSL+H FTCHD GATVL YAPK QLLISGGRKG   +FD+ QRQ   
Sbjct: 2863 RNVCLWDTLVAPANSLVHAFTCHDSGATVLAYAPKHQLLISGGRKGFTYVFDLCQRQQRQ 2922

Query: 2937 TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAG 2996
             FQ+HDS +KA+A+DP EEYF TGSAEGNIK+W L+  GL+H+F SEHA+QSIFRNIG G
Sbjct: 2923 LFQSHDSPVKAVAVDPTEEYFVTGSAEGNIKIWSLSTFGLLHTFVSEHARQSIFRNIGTG 2982

Query: 2997 VMQIDIIQGNRLFSCGADGTLKTRVLPNAFNIPNRIL 3033
            VMQI+    N +FSCGADGT+K R+LP+ F+  N +L
Sbjct: 2983 VMQIETGPANHIFSCGADGTMKMRILPDQFSPLNEVL 3019


>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
          Length = 369

 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839
            +G++D +VR++      +   FR A  A V  ++F S G     A  +  + +W  ++  
Sbjct: 40   SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 98

Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897
               +   +++W   +K + D   I S+S         D++ V LWD         +H + 
Sbjct: 99   FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 146

Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957
             H    T + + P    + + G    V ++D+R  +L+  +Q H +A+  L+  P   Y 
Sbjct: 147  EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 206

Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979
             T S++  +K+  L    L+++
Sbjct: 207  ITASSDSTLKILDLMEGRLLYT 228



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%)

Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813
            G S + + +   V+ +      Q ++T + D +V+++   R + L    Q  N  V    
Sbjct: 56   GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 114

Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873
            F+  G     A  +  + +W      S+ +   S+  H    +   F  S + +A +G  
Sbjct: 115  FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 170

Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933
            N    V +WD      + L+  +  H      L + P    LI+      + I D+ + +
Sbjct: 171  N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 224

Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
            L++T   H      +A     EYF +G ++  + VW+
Sbjct: 225  LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 261



 Score = 43.5 bits (101), Expect = 0.003
 Identities = 42/228 (18%), Positives = 85/228 (37%), Gaps = 20/228 (8%)

Query: 2792 WTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQC 2850
            W    Q   +R  G+   VT + F+  G+       +  + IW  N    +      ++ 
Sbjct: 8    WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTV----FRA 63

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910
            H+       F +      T+   +D++ V +W T        +   + H +     +++P
Sbjct: 64   HTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQHINWVRCAKFSP 117

Query: 2911 KQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
              +L++S      V ++D   R+ +H++  H   +  +   P          +  +KVW 
Sbjct: 118  DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWD 177

Query: 2971 LTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018
            +  H L+  ++   A  +     G          GN L +  +D TLK
Sbjct: 178  VRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 216


>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
          Length = 359

 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839
            +G++D +VR++      +   FR A  A V  ++F S G     A  +  + +W  ++  
Sbjct: 78   SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136

Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897
               +   +++W   +K + D   I S+S         D++ V LWD         +H + 
Sbjct: 137  FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 184

Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957
             H    T + + P    + + G    V ++D+R  +L+  +Q H +A+  L+  P   Y 
Sbjct: 185  EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244

Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979
             T S++  +K+  L    L+++
Sbjct: 245  ITASSDSTLKILDLMEGRLLYT 266



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%)

Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813
            G S + + +   V+ +      Q ++T + D +V+++   R + L    Q  N  V    
Sbjct: 94   GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 152

Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873
            F+  G     A  +  + +W      S+ +   S+  H    +   F  S + +A +G  
Sbjct: 153  FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208

Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933
            N    V +WD      + L+  +  H      L + P    LI+      + I D+ + +
Sbjct: 209  N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 262

Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
            L++T   H      +A     EYF +G ++  + VW+
Sbjct: 263  LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 22/240 (9%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            +G+ D  + +  W    Q   +R  G+   VT + F+  G+       +  + IW  N  
Sbjct: 36   SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              +      ++ H+       F +      T+   +D++ V +W T        +   + 
Sbjct: 94   GESTV----FRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQ 143

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H +     +++P  +L++S      V ++D   R+ +H++  H   +  +   P      
Sbjct: 144  HINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIA 203

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018
                +  +KVW +  H L+  ++   A  +     G          GN L +  +D TLK
Sbjct: 204  AAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 254



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 1/103 (0%)

Query: 2867 VATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCI 2926
            + T   ++ + + CL    + P  S  + FT H    T + ++P   LL SG R   V I
Sbjct: 29   INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87

Query: 2927 FDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
            +    +     F+AH + ++++      + F T S +  +KVW
Sbjct: 88   WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%)

Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950
            SL   F  H    T + ++   + L SG     + ++ ++ +   + F  H  A+  +  
Sbjct: 10   SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69

Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFS 3010
             P      +GS +  +++W       + + K E    ++FR   A V  +      + F 
Sbjct: 70   SPSGHLLASGSRDKTVRIW-------VPNVKGE---STVFRAHTATVRSVHFCSDGQSFV 119

Query: 3011 CGAD 3014
              +D
Sbjct: 120  TASD 123


>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
          Length = 407

 Score = 63.9 bits (154), Expect = 2e-09
 Identities = 45/202 (22%), Positives = 90/202 (44%), Gaps = 15/202 (7%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839
            +G++D +VR++      +   FR A  A V  ++F S G     A  +  + +W  ++  
Sbjct: 78   SGSRDKTVRIWVPNVKGESTVFR-AHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQK 136

Query: 2840 S--NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFT 2897
               +   +++W   +K + D   I S+S         D++ V LWD         +H + 
Sbjct: 137  FLFSLSQHINWVRCAKFSPDGRLIVSAS---------DDKTVKLWD---KSSRECVHSYC 184

Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957
             H    T + + P    + + G    V ++D+R  +L+  +Q H +A+  L+  P   Y 
Sbjct: 185  EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244

Query: 2958 TTGSAEGNIKVWRLTGHGLIHS 2979
             T S++  +K+  L    L+++
Sbjct: 245  ITASSDSTLKILDLMEGRLLYT 266



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 45/217 (20%), Positives = 87/217 (40%), Gaps = 11/217 (5%)

Query: 2754 GASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLY 2813
            G S + + +   V+ +      Q ++T + D +V+++   R + L    Q  N  V    
Sbjct: 94   GESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINW-VRCAK 152

Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873
            F+  G     A  +  + +W      S+ +   S+  H    +   F  S + +A +G  
Sbjct: 153  FSPDGRLIVSASDDKTVKLWD----KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMD 208

Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933
            N    V +WD      + L+  +  H      L + P    LI+      + I D+ + +
Sbjct: 209  N---TVKVWDVRT---HRLLQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILDLMEGR 262

Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
            L++T   H      +A     EYF +G ++  + VW+
Sbjct: 263  LLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWK 299



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 22/240 (9%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNA-RVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            +G+ D  + +  W    Q   +R  G+   VT + F+  G+       +  + IW  N  
Sbjct: 36   SGSMDSCLMV--WHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVK 93

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              +      ++ H+       F +      T+   +D++ V +W T        +   + 
Sbjct: 94   GESTV----FRAHTATVRSVHFCSDGQSFVTA---SDDKTVKVWAT---HRQKFLFSLSQ 143

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H +     +++P  +L++S      V ++D   R+ +H++  H   +  +   P      
Sbjct: 144  HINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIA 203

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGADGTLK 3018
                +  +KVW +  H L+  ++   A  +     G          GN L +  +D TLK
Sbjct: 204  AAGMDNTVKVWDVRTHRLLQHYQLHSAAVN-----GLSFHP----SGNYLITASSDSTLK 254



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 1/103 (0%)

Query: 2867 VATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCI 2926
            + T   ++ + + CL    + P  S  + FT H    T + ++P   LL SG R   V I
Sbjct: 29   INTKQLASGSMDSCLMVWHMKP-QSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRI 87

Query: 2927 FDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
            +    +     F+AH + ++++      + F T S +  +KVW
Sbjct: 88   WVPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDKTVKVW 130



 Score = 33.5 bits (75), Expect = 3.3
 Identities = 23/124 (18%), Positives = 48/124 (38%), Gaps = 10/124 (8%)

Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950
            SL   F  H    T + ++   + L SG     + ++ ++ +   + F  H  A+  +  
Sbjct: 10   SLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNF 69

Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFS 3010
             P      +GS +  +++W       + + K E    ++FR   A V  +      + F 
Sbjct: 70   SPSGHLLASGSRDKTVRIW-------VPNVKGE---STVFRAHTATVRSVHFCSDGQSFV 119

Query: 3011 CGAD 3014
              +D
Sbjct: 120  TASD 123


>gi|19913369 transducin beta-like 3 [Homo sapiens]
          Length = 808

 Score = 59.3 bits (142), Expect = 6e-08
 Identities = 55/272 (20%), Positives = 110/272 (40%), Gaps = 32/272 (11%)

Query: 2735 SQVHPPSSLPWLGTGQTSTGASVLMKRNLHNVKRMTSHPVHQYYLTGAQDGSVRMFEWTR 2794
            S V   S+ P L   +  T A  ++  +   V  +        + + A+D SVR++   +
Sbjct: 348  SHVVVASNSPCLKVFELQTSACQILHGHTDIVLALDVFRKGWLFASCAKDQSVRIWRMNK 407

Query: 2795 PQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFL---------SIWQV------NQTA 2839
              Q++C  Q         + +S G  C     E FL          +W +        TA
Sbjct: 408  AGQVMCVAQGSG------HTHSVGTVCCSRLKESFLVTGSQDCTVKLWPLPKALLSKNTA 461

Query: 2840 SNPKPYM-----SWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIH 2894
             +  P +     + +CH K  +  A   +  L+AT    + +R   LW     P   L+ 
Sbjct: 462  PDNGPILLQAQTTQRCHDKDINSVAIAPNDKLLATG---SQDRTAKLWAL---PQCQLLG 515

Query: 2895 GFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYE 2954
             F+ H  G   +Q++P  Q+L +    G + ++ ++    + TF+ HD+++  +A     
Sbjct: 516  VFSGHRRGLWCVQFSPMDQVLATASADGTIKLWALQDFSCLKTFEGHDASVLKVAFVSRG 575

Query: 2955 EYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAK 2986
                +  ++G +K+W +  +  + +  +   K
Sbjct: 576  TQLLSSGSDGLVKLWTIKNNECVRTLDAHEDK 607



 Score = 58.5 bits (140), Expect = 1e-07
 Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 11/128 (8%)

Query: 2898 CHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYF 2957
            CHD     +  AP  +LL +G +     ++ + Q QL+  F  H   +  +   P ++  
Sbjct: 477  CHDKDINSVAIAPNDKLLATGSQDRTAKLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVL 536

Query: 2958 TTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDII-QGNRLFSCGADGT 3016
             T SA+G IK+W L     + +F+             A V+++  + +G +L S G+DG 
Sbjct: 537  ATASADGTIKLWALQDFSCLKTFEGH----------DASVLKVAFVSRGTQLLSSGSDGL 586

Query: 3017 LKTRVLPN 3024
            +K   + N
Sbjct: 587  VKLWTIKN 594



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 42/209 (20%), Positives = 86/209 (41%), Gaps = 26/209 (12%)

Query: 2777 YYLTGAQDGSVRMFEWTRPQQLVCFRQAGN-------ARVTRLYFNSQGNKCGVADGEGF 2829
            + +TG+QD +V++  W  P+ L+    A +       A+ T+   +   N   +A  +  
Sbjct: 436  FLVTGSQDCTVKL--WPLPKALLSKNTAPDNGPILLQAQTTQRCHDKDINSVAIAPNDKL 493

Query: 2830 LSIWQVNQTASNPKPYMSWQC--------HSKATSDFAFITSSSLVATSGHSNDNRNVCL 2881
            L+    ++TA   K +   QC        H +      F     ++AT+      +   L
Sbjct: 494  LATGSQDRTA---KLWALPQCQLLGVFSGHRRGLWCVQFSPMDQVLATASADGTIKLWAL 550

Query: 2882 WDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAH 2941
             D       S +  F  HD     + +  +   L+S G  G V ++ I+  + + T  AH
Sbjct: 551  QDF------SCLKTFEGHDASVLKVAFVSRGTQLLSSGSDGLVKLWTIKNNECVRTLDAH 604

Query: 2942 DSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
            +  +  L     +++  TG+++  + +W+
Sbjct: 605  EDKVWGLHCSRLDDHALTGASDSRVILWK 633



 Score = 35.8 bits (81), Expect = 0.66
 Identities = 17/79 (21%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 2904 TVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQA-HDSAIKALALDPYEEYFTTGSA 2962
            T    +P  ++L++  R   +  +  ++  +   ++A H + +  +A DP      TG  
Sbjct: 70   TAFDLSPDNEVLVTASRALLLAQWAWQEGSVTRLWKAIHTAPVATMAFDPTSTLLATGGC 129

Query: 2963 EGNIKVWRLTGHGLIHSFK 2981
            +G ++VW +  H   H F+
Sbjct: 130  DGAVRVWDIVRHYGTHHFR 148



 Score = 32.3 bits (72), Expect = 7.3
 Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 2/75 (2%)

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL--DPYEEY 2956
            H      + + P   LL +GG  G V ++DI +    H F+     +  +A   DP    
Sbjct: 108  HTAPVATMAFDPTSTLLATGGCDGAVRVWDIVRHYGTHHFRGSPGVVHLVAFHPDPTRLL 167

Query: 2957 FTTGSAEGNIKVWRL 2971
              + + +  I+VW L
Sbjct: 168  LFSSATDAAIRVWSL 182



 Score = 32.0 bits (71), Expect = 9.6
 Identities = 22/84 (26%), Positives = 35/84 (41%), Gaps = 12/84 (14%)

Query: 2897 TCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEE- 2955
            T H    T L ++     ++S GR     I+D++  Q   T    +S ++A  L P E  
Sbjct: 192  TAHYSAVTSLAFSADGHTMLSSGRDKICIIWDLQSCQATRTVPVFES-VEAAVLLPEEPV 250

Query: 2956 ----------YFTTGSAEGNIKVW 2969
                      YF T   +G ++VW
Sbjct: 251  SQLGVKSPGLYFLTAGDQGTLRVW 274


>gi|26665869 WD repeat domain 51B [Homo sapiens]
          Length = 478

 Score = 56.2 bits (134), Expect = 5e-07
 Identities = 49/229 (21%), Positives = 92/229 (40%), Gaps = 40/229 (17%)

Query: 2776 QYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQV 2835
            Q+  T ++D S++++   R + L             LY ++   +C     +G L +   
Sbjct: 115  QFLATASEDKSIKVWSMYRQRFLYS-----------LYRHTHWVRCAKFSPDGRLIV--- 160

Query: 2836 NQTASNPKPYMSW-----QCHSKATSDFAFIT------SSSLVATSGHSNDNRNVCLWDT 2884
              + S  K    W     QC +  +    F        S + +A++G    ++ V +WD 
Sbjct: 161  --SCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAG---SDQTVKVWDV 215

Query: 2885 LISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSA 2944
             +   N L+  +  H  G   + + P    LI+    G + I D+ + +LI+T Q H   
Sbjct: 216  RV---NKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGP 272

Query: 2945 IKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNI 2993
            +  ++     E F +G A+  + +WR        +F   H K    RN+
Sbjct: 273  VFTVSFSKGGELFASGGADTQVLLWRT-------NFDELHCKGLTKRNL 314



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 40/229 (17%), Positives = 88/229 (38%), Gaps = 22/229 (9%)

Query: 2792 WTRPQQLVCFRQAGNARV-TRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQC 2850
            W        +R  G+  V T + F+  GN    A  +  + +W  ++       +  ++ 
Sbjct: 45   WNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGK----FSEFKA 100

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910
            H+       F      +AT+   ++++++ +W          ++    H H     +++P
Sbjct: 101  HTAPVRSVDFSADGQFLATA---SEDKSIKVWSMY---RQRFLYSLYRHTHWVRCAKFSP 154

Query: 2911 KQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWR 2970
              +L++S      + I+D   +Q ++ F         +  +P      +  ++  +KVW 
Sbjct: 155  DGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214

Query: 2971 LTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDII-QGNRLFSCGADGTLK 3018
            +  + L+  ++              GV  I     GN L +  +DGTLK
Sbjct: 215  VRVNKLLQHYQVH----------SGGVNCISFHPSGNYLITASSDGTLK 253



 Score = 41.2 bits (95), Expect = 0.016
 Identities = 25/102 (24%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 2882 WDTLISPGNSLIHG----FTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHT 2937
            WDT +   N   H     +  H    T +Q++P   LL S  R   V ++   +R     
Sbjct: 38   WDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSE 97

Query: 2938 FQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHS 2979
            F+AH + ++++      ++  T S + +IKVW +     ++S
Sbjct: 98   FKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139


>gi|20357529 guanine nucleotide-binding protein, beta-2 subunit [Homo
            sapiens]
          Length = 340

 Score = 55.8 bits (133), Expect = 6e-07
 Identities = 52/236 (22%), Positives = 93/236 (39%), Gaps = 16/236 (6%)

Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            ++ +QDG + +++     ++       +  +T  Y  S GN       +   SI+ +   
Sbjct: 71   VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNFVACGGLDNICSIYSLKTR 129

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              N +       H+   S   F+  + ++ +SG +       LWD  I  G   + GF  
Sbjct: 130  EGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTT----CALWD--IETGQQTV-GFAG 182

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H      L  AP  +  +SG     + ++D+R      TF  H+S I A+A  P    FT
Sbjct: 183  HSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHESDINAVAFFPNGYAFT 242

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014
            TGS +   +++ L     +  +  +        NI  G+  +   +  RL   G D
Sbjct: 243  TGSDDATCRLFDLRADQELLMYSHD--------NIICGITSVAFSRSGRLLLAGYD 290


>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
          Length = 655

 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 31/119 (26%), Positives = 61/119 (51%), Gaps = 6/119 (5%)

Query: 2863 SSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKG 2922
            S  L+AT G   D+  V LW   I+  N ++   T H      ++    ++L+++G + G
Sbjct: 32   SGRLLATGG---DDCRVNLWS--INKPNCIM-SLTGHTSPVESVRLNTPEELIVAGSQSG 85

Query: 2923 HVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFK 2981
             + ++D+   +++ T   H + I +L   PY E+  +GS + NIK+W +   G +  ++
Sbjct: 86   SIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYR 144



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 20/73 (27%), Positives = 36/73 (49%)

Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLT 2972
            +LL +GG    V ++ I +   I +   H S ++++ L+  EE    GS  G+I+VW L 
Sbjct: 34   RLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLE 93

Query: 2973 GHGLIHSFKSEHA 2985
               ++ +     A
Sbjct: 94   AAKILRTLMGHKA 106



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 35/204 (17%), Positives = 72/204 (35%), Gaps = 11/204 (5%)

Query: 2780 TGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTA 2839
            TG  D  V ++   +P  ++       + V  +  N+           G + +W +    
Sbjct: 38   TGGDDCRVNLWSINKPNCIMSLT-GHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAA- 95

Query: 2840 SNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCH 2899
               K   +   H        F      VA+    + + N+ LWD         +  +  H
Sbjct: 96   ---KILRTLMGHKANICSLDFHPYGEFVASG---SQDTNIKLWDIR---RKGCVFRYRGH 146

Query: 2900 DHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTT 2959
                  L+++P  + L S      V ++D+   +++  F  H   +  +   P E    +
Sbjct: 147  SQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLAS 206

Query: 2960 GSAEGNIKVWRLTGHGLIHSFKSE 2983
            GS++  I+ W L    ++   + E
Sbjct: 207  GSSDRTIRFWDLEKFQVVSCIEGE 230


>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [Homo
            sapiens]
          Length = 340

 Score = 55.5 bits (132), Expect = 8e-07
 Identities = 52/236 (22%), Positives = 92/236 (38%), Gaps = 16/236 (6%)

Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            ++ +QDG + +++     ++       +  +T  Y  S GN       +   SI+ +   
Sbjct: 71   VSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTR 129

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              N +       H+   S   F+  + +V +SG +       LWD  I  G      FT 
Sbjct: 130  EGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTT----CALWD--IETGQQTTT-FTG 182

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H      L  AP  +L +SG       ++D+R+     TF  H+S I A+   P    F 
Sbjct: 183  HTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFA 242

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014
            TGS +   +++ L     + ++  +        NI  G+  +   +  RL   G D
Sbjct: 243  TGSDDATCRLFDLRADQELMTYSHD--------NIICGITSVSFSKSGRLLLAGYD 290


>gi|223005862 echinoderm microtubule associated protein like 6 [Homo
            sapiens]
          Length = 1958

 Score = 53.5 bits (127), Expect = 3e-06
 Identities = 43/146 (29%), Positives = 61/146 (41%), Gaps = 12/146 (8%)

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAP 2910
            H+      A     +LVAT G       +C+WD+      SL+     H HG   L +  
Sbjct: 60   HNDDIISLALHPDKTLVAT-GQVGKEPYICIWDSYNVQTVSLLKDV--HTHGVACLAFDS 116

Query: 2911 KQQLLISGG--RKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKV 2968
              Q L S G   K  VCI+D R+ +L+ +   H   I  ++ DPY+          +IK 
Sbjct: 117  DGQRLASVGLDAKNTVCIWDWRKGKLLASATGHSDRIFDISWDPYQPNRVVSCGVKHIKF 176

Query: 2969 WRLTGHGLIHSFKSEHAKQSIFRNIG 2994
            W L G+ L        AK+ IF   G
Sbjct: 177  WTLCGNALT-------AKRGIFGKTG 195



 Score = 40.8 bits (94), Expect = 0.021
 Identities = 34/131 (25%), Positives = 57/131 (43%), Gaps = 5/131 (3%)

Query: 2864 SSLVATSGHSNDNRNVC--LWDTLISPGNSLIHGFTCHDH-GATVLQYAPKQQLLISGGR 2920
            S      G +   R+ C  LWDT   P   +    T   + G ++     K   L++G +
Sbjct: 242  SMYACEEGFATGGRDGCIRLWDTDFKPITKIDLRETEQGYKGLSIRSVCWKADRLLAGTQ 301

Query: 2921 KGHVCIFDIRQRQL-IHTFQAH-DSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIH 2978
               +    +R+R   +   Q H +  + ALAL P +    TGS + ++++W L  H LI 
Sbjct: 302  DSEIFEVIVRERDKPMLILQGHCEGELWALALHPKKPLAVTGSDDRSVRLWSLADHALIA 361

Query: 2979 SFKSEHAKQSI 2989
                E A +S+
Sbjct: 362  RCNMEEAVRSV 372


>gi|21536371 telomerase-associated protein 1 [Homo sapiens]
          Length = 2627

 Score = 52.8 bits (125), Expect = 5e-06
 Identities = 39/120 (32%), Positives = 54/120 (45%), Gaps = 7/120 (5%)

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGF-TCHDHGATVLQYA 2909
            H    S  +F T    +AT G    +R++  WD        LIH F  CH    T   + 
Sbjct: 2060 HEGPVSCCSFSTDGGSLATGGR---DRSLLCWDVRTPKTPVLIHSFPACHRDWVTGCAWT 2116

Query: 2910 PKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
             K  LLIS    G V ++D    Q +  F  H SA+ A+A    EE+  + S +G +KVW
Sbjct: 2117 -KDNLLISCSSDGSVGLWDPESGQRLGQFLGHQSAVSAVA--AVEEHVVSVSRDGTLKVW 2173


>gi|13376840 WD repeat domain 61 [Homo sapiens]
          Length = 305

 Score = 52.4 bits (124), Expect = 7e-06
 Identities = 24/89 (26%), Positives = 46/89 (51%)

Query: 2892 LIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALD 2951
            L+H    H      L ++P  QLL++    G++ I+D++   L  T   H S +  +A  
Sbjct: 182  LLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGHASWVLNVAFC 241

Query: 2952 PYEEYFTTGSAEGNIKVWRLTGHGLIHSF 2980
            P + +F + S++ ++KVW +     +H+F
Sbjct: 242  PDDTHFVSSSSDKSVKVWDVGTRTCVHTF 270



 Score = 47.4 bits (111), Expect = 2e-04
 Identities = 26/80 (32%), Positives = 41/80 (51%), Gaps = 1/80 (1%)

Query: 2906 LQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGN 2965
            + Y+P  + L SG   G + IFDI   +L+HT + H   I++L   P  +   T S +G 
Sbjct: 154  IAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGY 213

Query: 2966 IKVWRLTGHGLIHSFKSEHA 2985
            IK++ +  H  +    S HA
Sbjct: 214  IKIYDVQ-HANLAGTLSGHA 232


>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
          Length = 357

 Score = 51.6 bits (122), Expect = 1e-05
 Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 18/205 (8%)

Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873
            F+  G+    A  +  + +W V     N   Y + + HS A  +  + T  S++ ++   
Sbjct: 74   FHPNGSTLASAGFDRLILLWNVYGDCDN---YATLKGHSGAVMELHYNTDGSMLFSA--- 127

Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933
            + ++ V +WD+        + G T   +     +  P  QL+ +G   G V ++DIR++ 
Sbjct: 128  STDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGP--QLVCTGSDDGTVKLWDIRKKA 185

Query: 2934 LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNI 2993
             I TFQ +   + A+  +   +   +G  + +IKVW L  + L ++ +  HA      ++
Sbjct: 186  AIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRG-HADSVTGLSL 243

Query: 2994 GAGVMQIDIIQGNRLFSCGADGTLK 3018
             +        +G+ L S   D T++
Sbjct: 244  SS--------EGSYLLSNAMDNTVR 260



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 35/161 (21%), Positives = 69/161 (42%), Gaps = 10/161 (6%)

Query: 2809 VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVA 2868
            V  L++N+ G+    A  +  +++W  ++T    K        S   S +       LV 
Sbjct: 112  VMELHYNTDGSMLFSASTDKTVAVWD-SETGERVKRLKGHT--SFVNSCYPARRGPQLVC 168

Query: 2869 TSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFD 2928
            T    +D+  V LWD       + I  F  + +    + +      +ISGG    + ++D
Sbjct: 169  TG---SDDGTVKLWDIR---KKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWD 221

Query: 2929 IRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
            +RQ +L +T + H  ++  L+L     Y  + + +  ++VW
Sbjct: 222  LRQNKLTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVW 262


>gi|21071067 TBP-associated factor 5 [Homo sapiens]
          Length = 800

 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 44/197 (22%), Positives = 81/197 (41%), Gaps = 11/197 (5%)

Query: 2773 PVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSI 2832
            P   Y L+ ++DG+VR++       LV ++   N  V    F+  G        +    +
Sbjct: 553  PDRNYLLSSSEDGTVRLWSLQTFTCLVGYK-GHNYPVWDTQFSPYGYYFVSGGHDRVARL 611

Query: 2833 WQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSL 2892
            W  +      +P   +  H    +   F  +S+ VAT    + +R V LWD L     + 
Sbjct: 612  WATDHY----QPLRIFAGHLADVNCTRFHPNSNYVATG---SADRTVRLWDVL---NGNC 661

Query: 2893 IHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDP 2952
            +  FT H      L ++P  + L +G   G V ++DI    ++   + H   + +L    
Sbjct: 662  VRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTDTVCSLRFSR 721

Query: 2953 YEEYFTTGSAEGNIKVW 2969
              E   +GS +  +++W
Sbjct: 722  DGEILASGSMDNTVRLW 738



 Score = 38.5 bits (88), Expect = 0.10
 Identities = 28/117 (23%), Positives = 49/117 (41%), Gaps = 13/117 (11%)

Query: 2873 SNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQR 2932
            S+++  V LW        + + G+  H++     Q++P     +SGG      ++     
Sbjct: 561  SSEDGTVRLWSLQTF---TCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRVARLWATDHY 617

Query: 2933 QLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRL---------TGH-GLIHS 2979
            Q +  F  H + +      P   Y  TGSA+  +++W +         TGH G IHS
Sbjct: 618  QPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHS 674


>gi|4504053 guanine nucleotide-binding protein, beta-3 subunit [Homo
            sapiens]
          Length = 340

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 51/236 (21%), Positives = 90/236 (38%), Gaps = 16/236 (6%)

Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            ++ +QDG + +++     ++       +  +T  Y  S GN       +   SI+ +   
Sbjct: 71   VSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPS-GNFVACGGLDNMCSIYNLKSR 129

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              N K       H+   S   F+  +++V +SG +       LWD       ++  G   
Sbjct: 130  EGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDTT----CALWDIETGQQKTVFVG--- 182

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H      L  +P   L ISG       ++D+R+     TF  H+S I A+   P  E   
Sbjct: 183  HTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAICFFPNGEAIC 242

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014
            TGS + + +++ L     +  F  E        +I  G+  +      RL   G D
Sbjct: 243  TGSDDASCRLFDLRADQELICFSHE--------SIICGITSVAFSLSGRLLFAGYD 290


>gi|216548382 WD repeat domain 47 isoform 3 [Homo sapiens]
          Length = 919

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)

Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916
            A  T S  +  SG  + ++ V  WD  + P    + G T H  G+ V   A  P  +LL 
Sbjct: 760  ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 816

Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973
            +G       ++DIR  +++ ++  H S ++++   P   Y  TGS +  IKV  L G
Sbjct: 817  TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 873



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%)

Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813
            V+ +  HP    Y  G+   ++R+  +          T  Q +V F++  + +  +  + 
Sbjct: 609  VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 668

Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869
            ++  G        + ++ +   N +T +   P + +  H     D AF+    S   +  
Sbjct: 669  WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 728

Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929
            S  + D  N+   D     G   + G T H     +  Y     ++ SG +   V  +D+
Sbjct: 729  SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 783

Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985
            R    +     TF    SA+ ++A+DP      TG  + +  ++ + G  ++ S+   H 
Sbjct: 784  RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 840

Query: 2986 KQSIFRNI 2993
              S  R++
Sbjct: 841  HSSDVRSV 848


>gi|216548378 WD repeat domain 47 isoform 1 [Homo sapiens]
          Length = 927

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)

Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916
            A  T S  +  SG  + ++ V  WD  + P    + G T H  G+ V   A  P  +LL 
Sbjct: 768  ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 824

Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973
            +G       ++DIR  +++ ++  H S ++++   P   Y  TGS +  IKV  L G
Sbjct: 825  TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 881



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%)

Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813
            V+ +  HP    Y  G+   ++R+  +          T  Q +V F++  + +  +  + 
Sbjct: 617  VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 676

Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869
            ++  G        + ++ +   N +T +   P + +  H     D AF+    S   +  
Sbjct: 677  WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 736

Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929
            S  + D  N+   D     G   + G T H     +  Y     ++ SG +   V  +D+
Sbjct: 737  SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 791

Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985
            R    +     TF    SA+ ++A+DP      TG  + +  ++ + G  ++ S+   H 
Sbjct: 792  RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 848

Query: 2986 KQSIFRNI 2993
              S  R++
Sbjct: 849  HSSDVRSV 856


>gi|216548347 WD repeat domain 47 isoform 2 [Homo sapiens]
          Length = 920

 Score = 50.8 bits (120), Expect = 2e-05
 Identities = 34/117 (29%), Positives = 55/117 (47%), Gaps = 5/117 (4%)

Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYA--PKQQLLI 2916
            A  T S  +  SG  + ++ V  WD  + P    + G T H  G+ V   A  P  +LL 
Sbjct: 761  ALYTWSGWMIASG--SQDKTVRFWDLRV-PSCVRVVGTTFHGTGSAVASVAVDPSGRLLA 817

Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTG 2973
            +G       ++DIR  +++ ++  H S ++++   P   Y  TGS +  IKV  L G
Sbjct: 818  TGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGAHYLLTGSYDMKIKVTDLQG 874



 Score = 38.9 bits (89), Expect = 0.078
 Identities = 47/248 (18%), Positives = 97/248 (39%), Gaps = 28/248 (11%)

Query: 2766 VKRMTSHPVHQYYLTGAQDGSVRMFEW----------TRPQQLVCFRQAGNAR--VTRLY 2813
            V+ +  HP    Y  G+   ++R+  +          T  Q +V F++  + +  +  + 
Sbjct: 610  VRAVAFHPAGGLYAVGSNSKTLRVCAYPDVIDPSAHETPKQPVVRFKRNKHHKGSIYCVA 669

Query: 2814 FNSQGNKCGVADGEGFLSIWQVN-QTASNPKPYMSWQCHSKATSDFAFIT---SSSLVAT 2869
            ++  G        + ++ +   N +T +   P + +  H     D AF+    S   +  
Sbjct: 670  WSPCGQLLATGSNDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILI 729

Query: 2870 SGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDI 2929
            S  + D  N+   D     G   + G T H     +  Y     ++ SG +   V  +D+
Sbjct: 730  SAGAGDC-NIYTTDCQRGQGLHALSGHTGH----ILALYTWSGWMIASGSQDKTVRFWDL 784

Query: 2930 RQRQLIH----TFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHA 2985
            R    +     TF    SA+ ++A+DP      TG  + +  ++ + G  ++ S+   H 
Sbjct: 785  RVPSCVRVVGTTFHGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSY---HP 841

Query: 2986 KQSIFRNI 2993
              S  R++
Sbjct: 842  HSSDVRSV 849


>gi|197927448 WD repeat domain 6 protein [Homo sapiens]
          Length = 1151

 Score = 49.7 bits (117), Expect = 4e-05
 Identities = 33/120 (27%), Positives = 60/120 (50%), Gaps = 7/120 (5%)

Query: 2859 AFITSSSLVATSGHSNDNRNVCLWDT--LISPGNSLIHGFTCHDHGATVLQYAPKQQLLI 2916
            +++ S  L+AT+   +++R+V +W    L  PG  + +   C  H A V Q    +  LI
Sbjct: 246  SYLESKGLLATA---SEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLI 302

Query: 2917 SGGRKGHVCIFDIRQRQLIHTFQAHDS-AIKALALDPYEEYFTTGSAEGNIKVWRLTGHG 2975
            S G +  VC+    + +++  F+ H    I+A+A    + +  TG  +  I++W L G G
Sbjct: 303  SAG-EDCVCLVWSHEGEILQAFRGHQGRGIRAIAAHERQAWVITGGDDSGIRLWHLVGRG 361


>gi|221219020 NYD-SP11 protein [Homo sapiens]
          Length = 2873

 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 11/94 (11%)

Query: 2884 TLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDS 2943
            T  S G+S+   FTC D G            L +G + G + ++ ++Q   +H+FQAH S
Sbjct: 197  TSTSSGSSITCCFTCFDQG-----------FLYAGNQAGEIQVWSLQQGHPLHSFQAHQS 245

Query: 2944 AIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLI 2977
             +  +   P      T  ++  IK W LT   L+
Sbjct: 246  GVICIRSRPEAHTLLTAGSDSLIKEWNLTSGSLL 279


>gi|5174447 guanine nucleotide binding protein (G protein), beta
            polypeptide 2-like 1 [Homo sapiens]
          Length = 317

 Score = 48.9 bits (115), Expect = 8e-05
 Identities = 50/213 (23%), Positives = 85/213 (39%), Gaps = 20/213 (9%)

Query: 2776 QYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQ 2834
            Q+ L+G+ DG++R+  W         R  G+ + V  + F+S   +      +  + +W 
Sbjct: 76   QFALSGSWDGTLRL--WDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLW- 132

Query: 2835 VNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGN---- 2890
               T    K  +  + HS+  S   F  +S        SN     C WD L+   N    
Sbjct: 133  --NTLGVCKYTVQDESHSEWVSCVRFSPNS--------SNPIIVSCGWDKLVKVWNLANC 182

Query: 2891 SLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALAL 2950
             L      H      +  +P   L  SGG+ G   ++D+ + + ++T    D  I AL  
Sbjct: 183  KLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD-IINALCF 241

Query: 2951 DPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSE 2983
             P   Y+   +   +IK+W L G  ++   K E
Sbjct: 242  SP-NRYWLCAATGPSIKIWDLEGKIIVDELKQE 273


>gi|16554629 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 11/177 (6%)

Query: 2794 RPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHS 2852
            +P   + F  AG+ + V+ + F+  G     +  +  + IW     A + K   +   H 
Sbjct: 32   KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG----AYDGKFEKTISGHK 87

Query: 2853 KATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQ 2912
               SD A+ + S+L+ ++   +D++ + +WD  +S G  L      H +      + P+ 
Sbjct: 88   LGISDVAWSSDSNLLVSA---SDDKTLKIWD--VSSGKCL-KTLKGHSNYVFCCNFNPQS 141

Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
             L++SG     V I+D++  + + T  AH   + A+  +       + S +G  ++W
Sbjct: 142  NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198


>gi|16554627 WD repeat domain 5 [Homo sapiens]
          Length = 334

 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 38/177 (21%), Positives = 79/177 (44%), Gaps = 11/177 (6%)

Query: 2794 RPQQLVCFRQAGNAR-VTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHS 2852
            +P   + F  AG+ + V+ + F+  G     +  +  + IW     A + K   +   H 
Sbjct: 32   KPNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWG----AYDGKFEKTISGHK 87

Query: 2853 KATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQ 2912
               SD A+ + S+L+ ++   +D++ + +WD  +S G  L      H +      + P+ 
Sbjct: 88   LGISDVAWSSDSNLLVSA---SDDKTLKIWD--VSSGKCL-KTLKGHSNYVFCCNFNPQS 141

Query: 2913 QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVW 2969
             L++SG     V I+D++  + + T  AH   + A+  +       + S +G  ++W
Sbjct: 142  NLIVSGSFDESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIW 198


>gi|5803221 WD repeat-containing protein 3 [Homo sapiens]
          Length = 943

 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 45/226 (19%), Positives = 94/226 (41%), Gaps = 12/226 (5%)

Query: 2769 MTSHPVHQYYLTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKC-GVADGE 2827
            M+  P  + ++TG  D SV+ +++   +     ++  + + TR     +   C   +  +
Sbjct: 502  MSLSPDQRGFVTGGADKSVKFWDFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQ 561

Query: 2828 GFLSIWQVNQTAS-----NPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLW 2882
              L++  ++ T         K ++S   H             +L+AT    + +RNV +W
Sbjct: 562  KLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATG---SADRNVKIW 618

Query: 2883 DTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHD 2942
                   +  +     HD     LQ+ PK  L  + G+   +  +D  + + I T + H 
Sbjct: 619  GLDFGDCHKSLFA---HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHH 675

Query: 2943 SAIKALALDPYEEYFTTGSAEGNIKVWRLTGHGLIHSFKSEHAKQS 2988
              I  LA+ P  +Y  + S + ++++W  T   LI   + E  +++
Sbjct: 676  QEIWCLAVSPSGDYVVSSSHDKSLRLWERTREPLILEEEREMEREA 721



 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 18/62 (29%), Positives = 36/62 (58%)

Query: 2908 YAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIK 2967
            + P  + ++ G + G + ++D+    L+ T  AHD A+ +++L P +  F TG A+ ++K
Sbjct: 462  FVPGDRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVK 521

Query: 2968 VW 2969
             W
Sbjct: 522  FW 523



 Score = 40.0 bits (92), Expect = 0.035
 Identities = 51/258 (19%), Positives = 99/258 (38%), Gaps = 23/258 (8%)

Query: 2789 MFEWT-RPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMS 2847
            +F W  R  + +   Q     VT L  +  G    V   +G + I+ +     N    ++
Sbjct: 47   VFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEGN----VT 102

Query: 2848 WQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQ 2907
            +  H  A +   +      +A+     D   + +WD +   G   + G   H    T   
Sbjct: 103  FNGHKAAITTLKYDQLGGRLASGSKDTD---IIVWDVINESGLYRLKG---HKDAITQAL 156

Query: 2908 YAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIK 2967
            +  ++ LL++ G+   V  +D+  +    T   H + +  L L   E+   TG+++  ++
Sbjct: 157  FLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGHRTEVWGLVLLSEEKRLITGASDSELR 216

Query: 2968 VWRLTGHGLIHSFKSEHAKQSIFRNIGA--------GVMQIDIIQGNRLFSCGADGTL-- 3017
            VW +     I   +    K+    + G         G  + D    +R+ SC   G++  
Sbjct: 217  VWDIAYLQEIEDPEEPDPKKIKGSSPGIQDTLEAEDGAFETDEAPEDRILSCRKAGSIMR 276

Query: 3018 --KTRVLPNAFNIPNRIL 3033
              + RV+  A +   RIL
Sbjct: 277  EGRDRVVNLAVDKTGRIL 294


>gi|16418439 WD repeat and FYVE domain containing 2 [Homo sapiens]
          Length = 400

 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 43/206 (20%), Positives = 81/206 (39%), Gaps = 21/206 (10%)

Query: 2814 FNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHS 2873
            FN +  +  +    G +S + +++  +   P  ++Q H    +   F+     V ++G  
Sbjct: 76   FNPETRRLSIGLDNGTISEFILSEDYNKMTPVKNYQAHQSRVTMILFVLELEWVLSTGQD 135

Query: 2874 NDNRNVCLWDTLISPGNSLIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQ 2933
                  C      S     + G+      A+ LQ+  + + +  G   G V I  + Q  
Sbjct: 136  KQFAWHC------SESGQRLGGYRT-SAVASGLQFDVETRHVFIGDHSGQVTILKLEQEN 188

Query: 2934 --LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRLTGH-GLIHSFKSEHAKQSIF 2990
              L+ TF+ H   + AL  DP +    +GS++ ++ +W + G  G     +  + +    
Sbjct: 189  CTLVTTFRGHTGGVTALCWDPVQRVLFSGSSDHSVIMWDIGGRKGTAIELQGHNDR---- 244

Query: 2991 RNIGAGVMQIDIIQGNR-LFSCGADG 3015
                  V  +   Q  R L SCG DG
Sbjct: 245  ------VQALSYAQHTRQLISCGGDG 264



 Score = 40.0 bits (92), Expect = 0.035
 Identities = 44/178 (24%), Positives = 72/178 (40%), Gaps = 26/178 (14%)

Query: 2803 QAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQTASNPKPYMSWQCHSKATSDFAFIT 2862
            QA  +RVT + F        V + E  LS  Q  Q A        W C S++        
Sbjct: 111  QAHQSRVTMILF--------VLELEWVLSTGQDKQFA--------WHC-SESGQRLGGYR 153

Query: 2863 SSSLVATSGHSNDNRNVCLWD--------TLISPGNSLIHGFTCHDHGATVLQYAPKQQL 2914
            +S++ +      + R+V + D         L     +L+  F  H  G T L + P Q++
Sbjct: 154  TSAVASGLQFDVETRHVFIGDHSGQVTILKLEQENCTLVTTFRGHTGGVTALCWDPVQRV 213

Query: 2915 LISGGRKGHVCIFDIRQRQ-LIHTFQAHDSAIKALALDPYEEYFTTGSAEGNIKVWRL 2971
            L SG     V ++DI  R+      Q H+  ++AL+   +     +   +G I VW +
Sbjct: 214  LFSGSSDHSVIMWDIGGRKGTAIELQGHNDRVQALSYAQHTRQLISCGGDGGIVVWNM 271


>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
          Length = 446

 Score = 47.0 bits (110), Expect = 3e-04
 Identities = 33/144 (22%), Positives = 70/144 (48%), Gaps = 15/144 (10%)

Query: 2833 WQVNQTASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNS- 2891
            W V+Q     +P++    H+++  D  +  + + V  S   + + ++ +WD   +P  + 
Sbjct: 250  WHVDQ-----RPFVG---HTRSVEDLQWSPTENTVFAS--CSADASIRIWDIRAAPSKAC 299

Query: 2892 LIHGFTCHDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQL---IHTFQAHDSAIKAL 2948
            ++   T HD    V+ ++ ++  L+SGG  G + I+D+RQ +    + TF+ H + + ++
Sbjct: 300  MLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSV 359

Query: 2949 ALDPYEE-YFTTGSAEGNIKVWRL 2971
               P +   F    A+  I  W L
Sbjct: 360  EWHPQDSGVFAASGADHQITQWDL 383


>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [Homo
            sapiens]
          Length = 340

 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 49/236 (20%), Positives = 89/236 (37%), Gaps = 16/236 (6%)

Query: 2779 LTGAQDGSVRMFEWTRPQQLVCFRQAGNARVTRLYFNSQGNKCGVADGEGFLSIWQVNQT 2838
            ++ +QDG + +++     ++       +  +T  Y  S GN       +   SI+ +   
Sbjct: 71   VSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPS-GNYVACGGLDNICSIYNLKTR 129

Query: 2839 ASNPKPYMSWQCHSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTC 2898
              N +       H+   S   F+  S +V +SG +       LWD   +   +    FT 
Sbjct: 130  EGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTT----CALWDIETAQQTTT---FTG 182

Query: 2899 HDHGATVLQYAPKQQLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFT 2958
            H      L  +P  +  +SG       ++DIR      +F  H S I A++  P    F 
Sbjct: 183  HSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVSDINAVSFFPNGYAFA 242

Query: 2959 TGSAEGNIKVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCGAD 3014
            TGS +   +++ L     +  +  +        NI  G+  +   +  RL   G D
Sbjct: 243  TGSDDATCRLFDLRADQELLLYSHD--------NIICGITSVAFSKSGRLLLAGYD 290


>gi|5729852 guanine nucleotide-binding protein, beta-5 subunit isoform
            a [Homo sapiens]
          Length = 353

 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 20/166 (12%)

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVL--QY 2908
            H+   S  +F  S   + T+   + +    LWD        L+  F  H HGA VL    
Sbjct: 152  HTNYLSACSFTNSDMQILTA---SGDGTCALWDV---ESGQLLQSF--HGHGADVLCLDL 203

Query: 2909 APKQ--QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNI 2966
            AP +     +SGG      ++D+R  Q +  F+ H+S I ++   P  + F +GS +   
Sbjct: 204  APSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATC 263

Query: 2967 KVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCG 3012
            +++ L     +  +  E        +I  G   +D     RL   G
Sbjct: 264  RLYDLRADREVAIYSKE--------SIIFGASSVDFSLSGRLLFAG 301


>gi|20336270 guanine nucleotide-binding protein, beta-5 subunit
            isoform b [Homo sapiens]
          Length = 395

 Score = 46.6 bits (109), Expect = 4e-04
 Identities = 40/166 (24%), Positives = 67/166 (40%), Gaps = 20/166 (12%)

Query: 2851 HSKATSDFAFITSSSLVATSGHSNDNRNVCLWDTLISPGNSLIHGFTCHDHGATVL--QY 2908
            H+   S  +F  S   + T+   + +    LWD        L+  F  H HGA VL    
Sbjct: 194  HTNYLSACSFTNSDMQILTA---SGDGTCALWDV---ESGQLLQSF--HGHGADVLCLDL 245

Query: 2909 APKQ--QLLISGGRKGHVCIFDIRQRQLIHTFQAHDSAIKALALDPYEEYFTTGSAEGNI 2966
            AP +     +SGG      ++D+R  Q +  F+ H+S I ++   P  + F +GS +   
Sbjct: 246  APSETGNTFVSGGCDKKAMVWDMRSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATC 305

Query: 2967 KVWRLTGHGLIHSFKSEHAKQSIFRNIGAGVMQIDIIQGNRLFSCG 3012
            +++ L     +  +  E        +I  G   +D     RL   G
Sbjct: 306  RLYDLRADREVAIYSKE--------SIIFGASSVDFSLSGRLLFAG 343


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.132    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 120,907,916
Number of Sequences: 37866
Number of extensions: 5627969
Number of successful extensions: 20043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 157
Number of HSP's that attempted gapping in prelim test: 18626
Number of HSP's gapped (non-prelim): 1419
length of query: 3036
length of database: 18,247,518
effective HSP length: 120
effective length of query: 2916
effective length of database: 13,703,598
effective search space: 39959691768
effective search space used: 39959691768
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 71 (32.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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