BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] (518 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] 1065 0.0 gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo ... 1065 0.0 gi|239757832 PREDICTED: hypothetical protein [Homo sapiens] 1012 0.0 gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] 728 0.0 gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] 728 0.0 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 57 4e-08 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 57 4e-08 gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho... 55 2e-07 gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho... 55 2e-07 gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho... 55 2e-07 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 55 2e-07 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 54 3e-07 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 54 3e-07 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 54 3e-07 gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 49 1e-05 gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 49 1e-05 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 48 2e-05 gi|4504733 insulin receptor substrate 4 [Homo sapiens] 47 5e-05 gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] 46 7e-05 gi|27262667 colony stimulating factor 1 isoform a precursor [Hom... 45 1e-04 gi|27262661 colony stimulating factor 1 isoform a precursor [Hom... 45 1e-04 gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e... 45 2e-04 gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d... 45 2e-04 gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a ... 45 2e-04 gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c ... 45 2e-04 gi|163965366 nascent polypeptide-associated complex alpha subuni... 45 2e-04 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 43 6e-04 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 42 0.001 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 42 0.001 gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 42 0.001 >gi|239752343 PREDICTED: hypothetical protein [Homo sapiens] Length = 518 Score = 1065 bits (2753), Expect = 0.0 Identities = 518/518 (100%), Positives = 518/518 (100%) Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 >gi|239746856 PREDICTED: hypothetical protein XP_002343859 [Homo sapiens] Length = 518 Score = 1065 bits (2753), Expect = 0.0 Identities = 518/518 (100%), Positives = 518/518 (100%) Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL Sbjct: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 >gi|239757832 PREDICTED: hypothetical protein [Homo sapiens] Length = 503 Score = 1012 bits (2617), Expect = 0.0 Identities = 491/493 (99%), Positives = 492/493 (99%) Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT Sbjct: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG Sbjct: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER Sbjct: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP Sbjct: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV Sbjct: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP Sbjct: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL Sbjct: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ Sbjct: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 Query: 481 QPPGAQGCPRCIL 493 QPPGAQGCPR +L Sbjct: 481 QPPGAQGCPRVML 493 >gi|223468693 hypothetical protein LOC100130361 [Homo sapiens] Length = 514 Score = 728 bits (1878), Expect = 0.0 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%) Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56 Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG Sbjct: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER Sbjct: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK Sbjct: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236 Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V Sbjct: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP Sbjct: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L Sbjct: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ Sbjct: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 Query: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 QPPGAQGCPRCI LQREIEDL QLAAMQFLTDKFQDL Sbjct: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 >gi|223468690 hypothetical protein LOC100132994 [Homo sapiens] Length = 514 Score = 728 bits (1878), Expect = 0.0 Identities = 373/518 (72%), Positives = 407/518 (78%), Gaps = 4/518 (0%) Query: 1 MSSTDEVSVCRAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFT 60 MSS D+VSVC AG EGG++AG+ TASPGAP HG DL G G GK ESGFT Sbjct: 1 MSSPDKVSVCGAGFDLEGGKKAGSRTASPGAPGAHSHGLDLGV----PGSGDGKSESGFT 56 Query: 61 DPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQG 120 DPE FSFESESELIEQGRVVLWG+EGRPGTPVDDQ DYSFYLADEPA I+PP SVQG Sbjct: 57 DPEGFSFESESELIEQGRVVLWGREGRPGTPVDDQGDVVDYSFYLADEPAAIVPPPSVQG 116 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPER 180 HP PEGA A+GS + WAD EVGPS R L SPG+WQQASAG LHL PGP AW+NPER Sbjct: 117 HPFPEGAAAEGSAENWADAEVGPSGRDVLGHSPGKWQQASAGRLHLCGPGPVRAWKNPER 176 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKP 240 GSKSR S +VDPQQPSA+GP L T DSDSADESSDLP+++V I EGSQAKPGSPKK Sbjct: 177 GSKSRWSLRVDPQQPSAKGPTRLPTHDSDSADESSDLPLMKVGICRNEGSQAKPGSPKKR 236 Query: 241 GDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGV 300 DT + SFH +ESYL V G L S PR LTPV ERPAVGEL+ KKMQS WGK V Sbjct: 237 ADTSRQASFHCKESYLPVPGRFLTSAPRGLTPVAERPAVGELEDSPQKKMQSRAWGKVEV 296 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 RPSCSGAA G LP+G RK+A KKSL GA +LAL FPA G+RLSA PP+PA+FPP Sbjct: 297 RPSCSGAAAAGALPQGLSRRKMAGGKKSLGGASQLALGRGFPACGERLSAAPPEPATFPP 356 Query: 361 VSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 SGV G S +P++PKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPT +P L Sbjct: 357 FSGVRPQGMSKKPQKPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTHRPGL 416 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 LSVRRGE+SS DPNIRAPQ+ GTS+PSA++ LVPR HA SG+ QPPVHPPRPERQQ Sbjct: 417 PRLSVRRGEFSSSDPNIRAPQLPGTSEPSAYSPGGLVPRRHAPSGNQQPPVHPPRPERQQ 476 Query: 481 QPPGAQGCPRCILLQREIEDLRDQLAAMQFLTDKFQDL 518 QPPGAQGCPRCI LQREIEDL QLAAMQFLTDKFQDL Sbjct: 477 QPPGAQGCPRCIWLQREIEDLTQQLAAMQFLTDKFQDL 514 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 57.0 bits (136), Expect = 4e-08 Identities = 123/494 (24%), Positives = 165/494 (33%), Gaps = 106/494 (21%) Query: 15 GPEG--GEQAGAHTASPGAPRGD-GHGRDLNFGGQR--SGKGKGKGESGFTDPESFSFES 69 GP+G GE+ + A P GD G + G R +G+ G G P Sbjct: 525 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP--- 581 Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 G++GRPG P A G V G P P+GA Sbjct: 582 -------------GEDGRPGPPGPQGARG----------------QPGVMGFPGPKGANG 612 Query: 130 KGSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 + L P RG PG + + +AGP PGP GPA E E+G+ Sbjct: 613 EPGKAGEKGLPGAPGLRGL----PGKDGETGAAGP-----PGPAGPAGERGEQGAPGPSG 663 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG--DTCG 245 FQ P P G G K G Q PG PG G Sbjct: 664 FQGLPGPPGPPGEGG------------------------KPGDQGVPGEAGAPGLVGPRG 699 Query: 246 RRSFHRRESYLQVQGPLLISPPRRL--TPVVERP--AVGELDVPSLKKMQSMVWGKRGVR 301 R F QG + PR L TP + P A G P + G +G+ Sbjct: 700 ERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP 752 Query: 302 PSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL----ALRGAFPAWGQRLSAVPPDPA 356 A + GP RG +G K + +G L G A G++ PP PA Sbjct: 753 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 812 Query: 357 SFPPVSGV-GLLGKSVRPKEPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 413 G G G++ P + P G K + +A + D + P Sbjct: 813 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 872 Query: 414 PTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP 473 Q P ++ + + G P T P A R+ P S+G+ PP P Sbjct: 873 GPQGPTGVT-GPKGARGAQGPPG-------ATGFPGA--AGRVGP--PGSNGNPGPP-GP 919 Query: 474 PRPERQQQPPGAQG 487 P P + P GA+G Sbjct: 920 PGPSGKDGPKGARG 933 Score = 37.4 bits (85), Expect = 0.033 Identities = 121/493 (24%), Positives = 156/493 (31%), Gaps = 86/493 (17%) Query: 15 GPEG-----GEQAGAHTASPGAPRGD-GHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68 GP G GE+ A A P RGD G G+ G+G G G P + E Sbjct: 744 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIGPPGPAGANGE 802 Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128 + E+ G G G PG + G PA P G P +G Sbjct: 803 -KGEVGPPGPAGSAGARGAPGERGETGPPG----------PAGFAGPPGADGQPGAKGEQ 851 Query: 129 AKGST--DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVP-----GPGPAWENPERG 181 + D A GPS GA P GP ++ P GP G Sbjct: 852 GEAGQKGDAGAPGPQGPS--GAPGPQ---------GPTGVTGPKGARGAQGPPGATGFPG 900 Query: 182 SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241 + R+ P GP G + D P R +G PG +PG Sbjct: 901 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 960 Query: 242 DTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGV 300 D + +GP +V P GE P L S GK+G Sbjct: 961 D----------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSGEPGKQGA 1009 Query: 301 RPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 P SG RGP P G G + EG+P + PP Sbjct: 1010 -PGASGD--RGPPGPVGPPGLTGPAGEPGREGSPG--------------ADGPPGRDGAA 1052 Query: 360 PVSG----VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414 V G G +G P P SPG P G++ +A A+ P+ R Sbjct: 1053 GVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1110 Query: 415 TQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474 Q P R + +G+P R G FT + +P SGD Q P Sbjct: 1111 PQGP-------RGDKGEAGEPGER-----GLKGHRGFTGLQGLPGPPGPSGD-QGASGPA 1157 Query: 475 RPERQQQPPGAQG 487 P + PPG G Sbjct: 1158 GPSGPRGPPGPVG 1170 Score = 35.4 bits (80), Expect = 0.13 Identities = 67/271 (24%), Positives = 87/271 (32%), Gaps = 26/271 (9%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 R GP G G P +G+ G SGK KG G + P + E Sbjct: 887 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP-SGKDGPKGARGDSGPPGRAGEPG 945 Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSS-----VQGHPSPE 125 QG G++G PG A G LA + + P G P P Sbjct: 946 L----QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 1001 Query: 126 GATAK-----GSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPG-PGPAWENP 178 G K S D VGP + PG E + GP PG G A Sbjct: 1002 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PGRDGAAGVKG 1056 Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238 +RG + P P + GPAG D + + P+ + G Q G Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1116 Query: 239 KPGDT--CGRRSFHRRESYLQVQGPLLISPP 267 G+ G R + +QG L PP Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQG--LPGPP 1145 Score = 35.0 bits (79), Expect = 0.17 Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 24/170 (14%) Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADE---------PATIMPPSSVQGHPSPEGATAKGST 133 G+ GR G+P D G D + + + P PP G P P G T K Sbjct: 1032 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP----GSPGPAGPTGKQGD 1087 Query: 134 --DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191 + A +GPS P+ Q GP G A E ERG K F Sbjct: 1088 RGEAGAQGPMGPS-----GPAGARGIQGPQGPRG----DKGEAGEPGERGLKGHRGFTGL 1138 Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241 P GP+G + P V S K+G+ PG PG Sbjct: 1139 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1188 Score = 32.3 bits (72), Expect = 1.1 Identities = 112/487 (22%), Positives = 143/487 (29%), Gaps = 129/487 (26%) Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 +GP+G G Q A P RGD KGE G P Sbjct: 116 VGPKGPPGPQGPAGEQGPRGDRGD------------------KGEKGAPGPR-------- 149 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 G++G PGTP P PP G P P G Sbjct: 150 -----------GRDGEPGTP---------------GNPGPPGPP----GPPGPPGLGGNF 179 Query: 132 STDIWA--DLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQ 189 + + D + G + G + Q GP+ P PGPA G+ FQ Sbjct: 180 AAQMAGGFDEKAGGAQLGVM--------QGPMGPMGPRGP-PGPA------GAPGPQGFQ 224 Query: 190 VDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSF 249 +P +P G +G G + PG P KPGD G Sbjct: 225 GNPGEPGEPGVSG------------------------PMGPRGPPGPPGKPGDD-GEAG- 258 Query: 250 HRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGVRPSCSGAA 308 + +GP R P V G P L + G GV+ Sbjct: 259 --KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPG 315 Query: 309 VRG-PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLL 367 G P P G G + + GA GA GQ A PP P P G G Sbjct: 316 ENGSPGPMGPRGLPGERGRTGPAGA-----AGARGNDGQPGPAGPPGPVG--PAGGPGFP 368 Query: 368 GK-----SVRPKEPKHSSPGKKPAGRK-TRESQAAAREDNDPNRDEVPRAQLPTQKPELI 421 G P + + P G T S A +P D +P A+ P + Sbjct: 369 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 428 Query: 422 SLSVRRGEYSSGDPNIRAPQ-VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 + G P R P G + P + P G+ Q P P P Q Sbjct: 429 G--------APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE-QGPKGEPGPAGPQ 479 Query: 481 QPPGAQG 487 PG G Sbjct: 480 GAPGPAG 486 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 57.0 bits (136), Expect = 4e-08 Identities = 123/494 (24%), Positives = 165/494 (33%), Gaps = 106/494 (21%) Query: 15 GPEG--GEQAGAHTASPGAPRGD-GHGRDLNFGGQR--SGKGKGKGESGFTDPESFSFES 69 GP+G GE+ + A P GD G + G R +G+ G G P Sbjct: 456 GPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP--- 512 Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 G++GRPG P A G V G P P+GA Sbjct: 513 -------------GEDGRPGPPGPQGARG----------------QPGVMGFPGPKGANG 543 Query: 130 KGSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 + L P RG PG + + +AGP PGP GPA E E+G+ Sbjct: 544 EPGKAGEKGLPGAPGLRGL----PGKDGETGAAGP-----PGPAGPAGERGEQGAPGPSG 594 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG--DTCG 245 FQ P P G G K G Q PG PG G Sbjct: 595 FQGLPGPPGPPGEGG------------------------KPGDQGVPGEAGAPGLVGPRG 630 Query: 246 RRSFHRRESYLQVQGPLLISPPRRL--TPVVERP--AVGELDVPSLKKMQSMVWGKRGVR 301 R F QG + PR L TP + P A G P + G +G+ Sbjct: 631 ERGFPGERGSPGAQG---LQGPRGLPGTPGTDGPKGASGPAGPPGAQGPP----GLQGMP 683 Query: 302 PSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL----ALRGAFPAWGQRLSAVPPDPA 356 A + GP RG +G K + +G L G A G++ PP PA Sbjct: 684 GERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPA 743 Query: 357 SFPPVSGV-GLLGKSVRPKEPKHSSP--GKKPAGRKTRESQAAAREDNDPNRDEVPRAQL 413 G G G++ P + P G K + +A + D + P Sbjct: 744 GSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAP 803 Query: 414 PTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP 473 Q P ++ + + G P T P A R+ P S+G+ PP P Sbjct: 804 GPQGPTGVT-GPKGARGAQGPPG-------ATGFPGA--AGRVGP--PGSNGNPGPP-GP 850 Query: 474 PRPERQQQPPGAQG 487 P P + P GA+G Sbjct: 851 PGPSGKDGPKGARG 864 Score = 37.4 bits (85), Expect = 0.033 Identities = 121/493 (24%), Positives = 156/493 (31%), Gaps = 86/493 (17%) Query: 15 GPEG-----GEQAGAHTASPGAPRGD-GHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68 GP G GE+ A A P RGD G G+ G+G G G P + E Sbjct: 675 GPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGL-TGPIGPPGPAGANGE 733 Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128 + E+ G G G PG + G PA P G P +G Sbjct: 734 -KGEVGPPGPAGSAGARGAPGERGETGPPG----------PAGFAGPPGADGQPGAKGEQ 782 Query: 129 AKGST--DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVP-----GPGPAWENPERG 181 + D A GPS GA P GP ++ P GP G Sbjct: 783 GEAGQKGDAGAPGPQGPS--GAPGPQ---------GPTGVTGPKGARGAQGPPGATGFPG 831 Query: 182 SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241 + R+ P GP G + D P R +G PG +PG Sbjct: 832 AAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPG 891 Query: 242 DTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGV 300 D + +GP +V P GE P L S GK+G Sbjct: 892 D----------DGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPG-PSGEPGKQGA 940 Query: 301 RPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 P SG RGP P G G + EG+P + PP Sbjct: 941 -PGASGD--RGPPGPVGPPGLTGPAGEPGREGSPG--------------ADGPPGRDGAA 983 Query: 360 PVSG----VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414 V G G +G P P SPG P G++ +A A+ P+ R Sbjct: 984 GVKGDRGETGAVGAPGAPGPP--GSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQG 1041 Query: 415 TQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474 Q P R + +G+P R G FT + +P SGD Q P Sbjct: 1042 PQGP-------RGDKGEAGEPGER-----GLKGHRGFTGLQGLPGPPGPSGD-QGASGPA 1088 Query: 475 RPERQQQPPGAQG 487 P + PPG G Sbjct: 1089 GPSGPRGPPGPVG 1101 Score = 35.4 bits (80), Expect = 0.13 Identities = 67/271 (24%), Positives = 87/271 (32%), Gaps = 26/271 (9%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 R GP G G P +G+ G SGK KG G + P + E Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGP-SGKDGPKGARGDSGPPGRAGEPG 876 Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSS-----VQGHPSPE 125 QG G++G PG A G LA + + P G P P Sbjct: 877 L----QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPS 932 Query: 126 GATAK-----GSTDIWADLEVGPSWRGALSPSPG-EWQQASAGPLHLSVPG-PGPAWENP 178 G K S D VGP + PG E + GP PG G A Sbjct: 933 GEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP-----PGRDGAAGVKG 987 Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238 +RG + P P + GPAG D + + P+ + G Q G Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRGEAGAQGPMGPSGPAGARGIQGPQGPRG 1047 Query: 239 KPGDT--CGRRSFHRRESYLQVQGPLLISPP 267 G+ G R + +QG L PP Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQG--LPGPP 1076 Score = 35.0 bits (79), Expect = 0.17 Identities = 46/170 (27%), Positives = 58/170 (34%), Gaps = 24/170 (14%) Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADE---------PATIMPPSSVQGHPSPEGATAKGST 133 G+ GR G+P D G D + + + P PP G P P G T K Sbjct: 963 GEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPP----GSPGPAGPTGKQGD 1018 Query: 134 --DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191 + A +GPS P+ Q GP G A E ERG K F Sbjct: 1019 RGEAGAQGPMGPS-----GPAGARGIQGPQGPRG----DKGEAGEPGERGLKGHRGFTGL 1069 Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241 P GP+G + P V S K+G+ PG PG Sbjct: 1070 QGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPG 1119 Score = 32.3 bits (72), Expect = 1.1 Identities = 112/487 (22%), Positives = 143/487 (29%), Gaps = 129/487 (26%) Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 +GP+G G Q A P RGD KGE G P Sbjct: 47 VGPKGPPGPQGPAGEQGPRGDRGD------------------KGEKGAPGPR-------- 80 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 G++G PGTP P PP G P P G Sbjct: 81 -----------GRDGEPGTP---------------GNPGPPGPP----GPPGPPGLGGNF 110 Query: 132 STDIWA--DLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQ 189 + + D + G + G + Q GP+ P PGPA G+ FQ Sbjct: 111 AAQMAGGFDEKAGGAQLGVM--------QGPMGPMGPRGP-PGPA------GAPGPQGFQ 155 Query: 190 VDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSF 249 +P +P G +G G + PG P KPGD G Sbjct: 156 GNPGEPGEPGVSG------------------------PMGPRGPPGPPGKPGDD-GEAG- 189 Query: 250 HRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMVWGKRGVRPSCSGAA 308 + +GP R P V G P L + G GV+ Sbjct: 190 --KPGKAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEA-GAPGVKGESGSPG 246 Query: 309 VRG-PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLL 367 G P P G G + + GA GA GQ A PP P P G G Sbjct: 247 ENGSPGPMGPRGLPGERGRTGPAGA-----AGARGNDGQPGPAGPPGPVG--PAGGPGFP 299 Query: 368 GK-----SVRPKEPKHSSPGKKPAGRK-TRESQAAAREDNDPNRDEVPRAQLPTQKPELI 421 G P + + P G T S A +P D +P A+ P + Sbjct: 300 GAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIA 359 Query: 422 SLSVRRGEYSSGDPNIRAPQ-VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQ 480 + G P R P G + P + P G+ Q P P P Q Sbjct: 360 G--------APGFPGPRGPPGPQGATGPLGPKGQTGEPGIAGFKGE-QGPKGEPGPAGPQ 410 Query: 481 QPPGAQG 487 PG G Sbjct: 411 GAPGPAG 417 >gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo sapiens] Length = 1818 Score = 55.1 bits (131), Expect = 2e-07 Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69 GP G +PG GDG G KG +G GF P + Sbjct: 1159 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1217 Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 E E G V G G PG P Q G AD P PP SV S G Sbjct: 1218 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1265 Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183 KG E G P G P ++ AGP + P GP ++ +G+ Sbjct: 1266 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1320 Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243 + F DP P GPAG D D+ D + G PG P K G Sbjct: 1321 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1377 Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302 G R+ +G PP + PV + G+ L+ + V G++G+ Sbjct: 1378 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1435 Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360 + GP+ P G G K K +G P L L G G++ P P Sbjct: 1436 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1495 Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413 G G + P P PG + P G K A + D+ P P ++ Sbjct: 1496 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1554 Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437 P L S RR G + D NI Sbjct: 1555 IQPLPILSSKKTRRHTEGMQADADDNI 1581 Score = 38.9 bits (89), Expect = 0.011 Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%) Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 GP G + T PG P DG G G+ KG+ GF + Sbjct: 574 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 623 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 +G G +G PG P DD G D P + + +G P G Sbjct: 624 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 675 Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 A ++ P +G + P PG QQ + GP L PGP GP E+G + + Sbjct: 676 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 733 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215 P A+GP G + S ++ + Sbjct: 734 L---AGLPGADGPPGHPGKEGQSGEKGA 758 Score = 34.3 bits (77), Expect = 0.28 Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 + LGP G + + G DG G + KG+ KGE GF + + Sbjct: 756 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 807 Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125 + E G++ G++G G P D G A E + P + G+P + Sbjct: 808 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 861 Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170 G KGST A+ E G P RG P+ + + GP P Sbjct: 862 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 919 Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218 PGP E +G + + F + P P +G G ++ + P Sbjct: 920 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 979 Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274 V+ T E G + PG P PG+ G +E GP IS + P Sbjct: 980 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 1036 Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331 R GE +P + + K G P V P RG T G + +G Sbjct: 1037 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1093 Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390 P A G A G++ P PA V G VGL G P P S G Sbjct: 1094 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1144 Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447 Q ++ D N P Q P P + G+P R Q + + Sbjct: 1145 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1196 Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487 P L+ L P +GD P P PP P Q P GA G Sbjct: 1197 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1249 >gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo sapiens] Length = 1767 Score = 55.1 bits (131), Expect = 2e-07 Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69 GP G +PG GDG G KG +G GF P + Sbjct: 1108 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1166 Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 E E G V G G PG P Q G AD P PP SV S G Sbjct: 1167 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1214 Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183 KG E G P G P ++ AGP + P GP ++ +G+ Sbjct: 1215 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1269 Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243 + F DP P GPAG D D+ D + G PG P K G Sbjct: 1270 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1326 Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302 G R+ +G PP + PV + G+ L+ + V G++G+ Sbjct: 1327 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1384 Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360 + GP+ P G G K K +G P L L G G++ P P Sbjct: 1385 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1444 Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413 G G + P P PG + P G K A + D+ P P ++ Sbjct: 1445 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1503 Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437 P L S RR G + D NI Sbjct: 1504 IQPLPILSSKKTRRHTEGMQADADDNI 1530 Score = 38.9 bits (89), Expect = 0.011 Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%) Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 GP G + T PG P DG G G+ KG+ GF + Sbjct: 523 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 572 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 +G G +G PG P DD G D P + + +G P G Sbjct: 573 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 624 Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 A ++ P +G + P PG QQ + GP L PGP GP E+G + + Sbjct: 625 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 682 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215 P A+GP G + S ++ + Sbjct: 683 L---AGLPGADGPPGHPGKEGQSGEKGA 707 Score = 34.3 bits (77), Expect = 0.28 Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 + LGP G + + G DG G + KG+ KGE GF + + Sbjct: 705 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 756 Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125 + E G++ G++G G P D G A E + P + G+P + Sbjct: 757 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 810 Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170 G KGST A+ E G P RG P+ + + GP P Sbjct: 811 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 868 Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218 PGP E +G + + F + P P +G G ++ + P Sbjct: 869 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 928 Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274 V+ T E G + PG P PG+ G +E GP IS + P Sbjct: 929 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 985 Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331 R GE +P + + K G P V P RG T G + +G Sbjct: 986 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1042 Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390 P A G A G++ P PA V G VGL G P P S G Sbjct: 1043 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1093 Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447 Q ++ D N P Q P P + G+P R Q + + Sbjct: 1094 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1145 Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487 P L+ L P +GD P P PP P Q P GA G Sbjct: 1146 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1198 >gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo sapiens] Length = 1806 Score = 55.1 bits (131), Expect = 2e-07 Identities = 115/447 (25%), Positives = 150/447 (33%), Gaps = 48/447 (10%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPES-FSFES---- 69 GP G +PG GDG G KG +G GF P + Sbjct: 1147 GPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGMFGQKGD-EGARGFPGPPGPIGLQGLPGP 1205 Query: 70 ESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 E E G V G G PG P Q G AD P PP SV S G Sbjct: 1206 PGEKGENGDVGPMGPPGPPG-PRGPQGPNG------ADGPQG--PPGSVG---SVGGVGE 1253 Query: 130 KGSTDIWADLEVG----PSWRGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSK 183 KG E G P G P ++ AGP + P GP ++ +G+ Sbjct: 1254 KGEPG-----EAGNPGPPGEAGVGGPKGERGEKGEAGPPGAAGPPGAKGPPGDDGPKGNP 1308 Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT 243 + F DP P GPAG D D+ D + G PG P K G Sbjct: 1309 GPVGFPGDPGPPGEPGPAG---QDGVGGDKGEDGDPGQPGPPGPSGEAGPPGPPGKRGPP 1365 Query: 244 CGRRSFHRRESYLQVQGPL-LISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302 G R+ +G PP + PV + G+ L+ + V G++G+ Sbjct: 1366 -GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGKPGPEGLRGIPGPV-GEQGLPG 1423 Query: 303 SCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAVPPDPASFPP 360 + GP+ P G G K K +G P L L G G++ P P Sbjct: 1424 AAGQDGPPGPMGPPGLPGLKGDPGSKGEKGHPGLIGLIGPPGEQGEKGDRGLPGTQGSPG 1483 Query: 361 VSGVGLLGKSVRPKEPKHSSPG----KKPAGRKTRESQAAAREDN---DPNRDEVPRAQL 413 G G + P P PG + P G K A + D+ P P ++ Sbjct: 1484 AKGDGGIPGPAGPLGPP-GPPGLPGPQGPKGNKGSTGPAGQKGDSGLPGPPGSPGPPGEV 1542 Query: 414 PTQKPELISLSVRR---GEYSSGDPNI 437 P L S RR G + D NI Sbjct: 1543 IQPLPILSSKKTRRHTEGMQADADDNI 1569 Score = 38.9 bits (89), Expect = 0.011 Identities = 53/208 (25%), Positives = 75/208 (36%), Gaps = 30/208 (14%) Query: 15 GPEGGEQAGAHTASPGA---PRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 GP G + T PG P DG G G+ KG+ GF + Sbjct: 562 GPRGVQGPPGPTGKPGKRGRPGADG-------GRGMPGEPGAKGDRGFDGLPGLPGD--- 611 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 +G G +G PG P DD G D P + + +G P G Sbjct: 612 ----KGHRGERGPQGPPGPPGDDGMRGEDGEI----GPRGLPGEAGPRGLLGPRGTPGAP 663 Query: 132 STDIWADLEVGPSWRGALSP--SPG-EWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 A ++ P +G + P PG QQ + GP L PGP GP E+G + + Sbjct: 664 GQPGMAGVDGPPGPKGNMGPQGEPGPPGQQGNPGPQGL--PGPQGPIGPPGEKGPQGKPG 721 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESS 215 P A+GP G + S ++ + Sbjct: 722 L---AGLPGADGPPGHPGKEGQSGEKGA 746 Score = 34.3 bits (77), Expect = 0.28 Identities = 129/533 (24%), Positives = 177/533 (33%), Gaps = 95/533 (17%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 + LGP G + + G DG G + KG+ KGE GF + + Sbjct: 744 KGALGPPGPQGPIGYPGPRGVKGADG------VRGLKGSKGE-KGEDGFPGFKG-DMGLK 795 Query: 71 SELIEQGRVVLWGQEGRPGT-----PVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPE 125 + E G++ G++G G P D G A E + P + G+P + Sbjct: 796 GDRGEVGQIGPRGEDGPEGPKGRAGPTGDPGPSGQ-----AGEKGKLGVPG-LPGYPGRQ 849 Query: 126 GATAKGSTDI----WADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPG---- 170 G KGST A+ E G P RG P+ + + GP P Sbjct: 850 GP--KGSTGFPGFPGANGEKGARGVAGKPGPRGQRGPTGPRGSRGARGPTGKPGPKGTSG 907 Query: 171 ----PGPAWENPERGSKSRLSF---QVDPQQPSAEGPAGLNTDDSDSADESSDLP----- 218 PGP E +G + + F + P P +G G ++ + P Sbjct: 908 GDGPPGPPGERGPQGPQGPVGFPGPKGPPGPPGKDGLPGHPGQRGETGFQGKTGPPGPGG 967 Query: 219 VIRVIISTKE----GSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVV 274 V+ T E G + PG P PG+ G +E GP IS + P Sbjct: 968 VVGPQGPTGETGPIGERGHPGPPGPPGEQ-GLPGAAGKEGAKGDPGPQGISG--KDGPAG 1024 Query: 275 ERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRG---TLGRKVAQEKKSLEG 331 R GE +P + + K G P V P RG T G + +G Sbjct: 1025 LRGFPGERGLPGAQGAPGL---KGGEGPQGPPGPVGSPGERGSAGTAGPIGLPGRPGPQG 1081 Query: 332 APELALRGAFPAWGQRLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKT 390 P A G A G++ P PA V G VGL G P P S G Sbjct: 1082 PPGPA--GEKGAPGEK---GPQGPAGRDGVQGPVGLPG----PAGPAGSPGEDGDKGEIG 1132 Query: 391 RESQAAAREDNDPNRDEVPRA-QLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQ-- 447 Q ++ D N P Q P P + G+P R Q + + Sbjct: 1133 EPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAG--------GDGEPGPRGQQGMFGQKGD 1184 Query: 448 ---------PSAFTLRRLV--PRCHASSGDWQP--PVHPPRPERQQQPPGAQG 487 P L+ L P +GD P P PP P Q P GA G Sbjct: 1185 EGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRGPQGPNGADG 1237 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 54.7 bits (130), Expect = 2e-07 Identities = 104/425 (24%), Positives = 149/425 (35%), Gaps = 58/425 (13%) Query: 15 GPEG--GEQAGAHTASPGAPRG----DGHGRDLNFGGQRSGKGKGKGESGFTDP------ 62 GP G G Q P P G DG ++ GQ+ KG KGE G P Sbjct: 1129 GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGD-KGEQGPPGPTGPQGP 1187 Query: 63 --ESFSFESESELIEQGRVVLWGQEGRPGT-----------------PVDDQAGGGDYSF 103 + ++ E +G+ L+GQ+G G P ++ GD Sbjct: 1188 IGQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQ 1247 Query: 104 YLADEPATIMPPSSVQGHPSPEGATAKGSTDIWADLEVG----------PSWRGALSPSP 153 P PS G P+G G + A E G P G P Sbjct: 1248 MGPPGPPGPRGPSGAPGADGPQGPPG-GIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKG 1306 Query: 154 GEWQQASAGPLHLS-VPGP-GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSA 211 ++ +GP + PGP GP ++ +GS + F DP P GPAG + D Sbjct: 1307 ERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKG 1366 Query: 212 DESSDLPVIRVIISTKEGSQAKPG--SPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRR 269 D+ + + G PG P P GR+ + ++G PP + Sbjct: 1367 DDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEG-----PPGK 1421 Query: 270 LTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKS 328 P+ + A G+ L+ + V G++G+ S GP+ P G G K K Sbjct: 1422 TGPIGPQGAPGKPGPDGLRGIPGPV-GEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKG 1480 Query: 329 LEGAPEL-ALRGAFPAWGQRLSAVPPDP-ASFPPVSGVGLLGKS--VRPKEPKHSSPGKK 384 +G P L L G G++ P P S P G+ G S + P P Sbjct: 1481 EKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPG 1540 Query: 385 PAGRK 389 P G K Sbjct: 1541 PKGAK 1545 Score = 45.4 bits (106), Expect = 1e-04 Identities = 123/510 (24%), Positives = 169/510 (33%), Gaps = 135/510 (26%) Query: 53 GKGESGFTDPESFSFESESE-LIEQGRVVL------WGQEGRPGTPVDDQAGGGDYSFYL 105 G G++G P + ES+++ +++Q R+ L G GRPG PV GG L Sbjct: 528 GGGDAGSKGPMVSAQESQAQAILQQARLALRGPAGPMGLTGRPG-PVGPPGSGG-----L 581 Query: 106 ADEPATIMP--PSSVQGHPSPEGATAK---GSTDIWADL--EVGPSW-RG--ALSPSPGE 155 EP + P P VQG P P G + +D + + GP RG L+ PGE Sbjct: 582 KGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDRGFDGLAGLPGE 641 Query: 156 -WQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQPSA------EGPAGLNTDDS 208 + GP S P PGP ++ ERG + + P +P +GP G Sbjct: 642 KGHRGDPGP---SGP-PGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPG 697 Query: 209 DSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPR 268 + + P V G Q +PG P + G+ QG L P Sbjct: 698 VTGMDGQPGPKGNV------GPQGEPGPPGQQGNP-------------GAQG--LPGPQG 736 Query: 269 RLTPVVERPAVGELDVPSLKKMQSMVW--GKRGVRPSCSGAAVRGPL-------PRGTLG 319 + P E+ +G+ +P + GK G G GP PRG G Sbjct: 737 AIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPIGYPGPRGVKG 796 Query: 320 R------KVAQEKKSLEGAPELALRGAFPAWGQRLSAVPP-------------------D 354 K + +K +G P +G G R PP D Sbjct: 797 ADGIRGLKGTKGEKGEDGFP--GFKGDMGIKGDRGEIGPPGPRGEDGPEGPKGRGGPNGD 854 Query: 355 PASFPPVSGVGLLGKSVRPKEPKHSSP-------------GKKPAGRKT--RESQAAARE 399 P P G LG P P P G+K GR T + R Sbjct: 855 PGPLGPPGEKGKLGVPGLPGYPGRQGPKGSIGFPGFPGANGEK-GGRGTPGKPGPRGQRG 913 Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPR 459 P + PR P+ S G+ +G P R P G P+ F Sbjct: 914 PTGPRGERGPRGITGKPGPKGNS----GGDGPAGPPGERGPN--GPQGPTGF-------- 959 Query: 460 CHASSGDWQPPVHPPRPERQQQPPGAQGCP 489 P P+ PPG G P Sbjct: 960 --------------PGPKGPPGPPGKDGLP 975 Score = 42.0 bits (97), Expect = 0.001 Identities = 62/204 (30%), Positives = 75/204 (36%), Gaps = 27/204 (13%) Query: 15 GPEGGEQAGAHTASPG-----APRG-DGHGRDLNFGGQR--SGKGKGKGESGFTDPESF- 65 GP G +G PG PRG G G+R +G +G G T P+ Sbjct: 571 GPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDGARGMPGQTGPKGDR 630 Query: 66 SFESESELI-EQGRVVLWGQEGRPGTPVDDQAGGGDYSFY---LADEPAT--IMPPSSVQ 119 F+ + L E+G G G PG P DD G D L EP ++ P Sbjct: 631 GFDGLAGLPGEKGHRGDPGPSGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPP 690 Query: 120 GHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGE-WQQASAGPLHLSVPGPGPAWENP 178 G P P G T D + GP PG QQ + G L PGP A P Sbjct: 691 GPPGPPGVTGM-------DGQPGPKGNVGPQGEPGPPGQQGNPGAQGL--PGPQGAIGPP 741 Query: 179 ERGSKSRLSFQVDPQQPSAEGPAG 202 G K L P P A+GP G Sbjct: 742 --GEKGPLGKPGLPGMPGADGPPG 763 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 53.9 bits (128), Expect = 3e-07 Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%) Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71 +GP G A PGA GH G R G G G P Sbjct: 1027 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1079 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129 E+G G G PG P G + AD P PP V G P +G Sbjct: 1080 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1130 Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186 + GS I + V GP RG Q GP PGP GP ++ +G+ + Sbjct: 1131 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1183 Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243 F DP P GP G D D D G +PGSP G+ Sbjct: 1184 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1228 Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294 G R+ +G P I P + PV G+ L+ + V Sbjct: 1229 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1288 Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351 G++G RP +G A GP+ P G G + K +G P L L G G++ Sbjct: 1289 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1346 Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399 P P P G +G+ G S P PK + P G K + Sbjct: 1347 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1406 Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453 P + + LP Q P+ SV D P AP G + S +L Sbjct: 1407 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1464 Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490 R + + +G P HP P+ + QGC R Sbjct: 1465 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1510 Score = 41.6 bits (96), Expect = 0.002 Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP G PG+P G DL G R G G T P + Sbjct: 404 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 449 Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134 +GR G G PG P G D L E + QG P P G + D Sbjct: 450 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 508 Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194 E+GP RG S GP + P PG + +G K L Q +P Sbjct: 509 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 561 Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241 P +G G + LP + I ++G Q KPG P PG Sbjct: 562 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 599 Score = 41.6 bits (96), Expect = 0.002 Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72 GPEG + T PG P G L G G+ KG GF S E + Sbjct: 683 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 742 Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121 + E+G GQ G G A GGD E + P G Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 801 Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168 P P+G D L P RG + P P + GP+ Sbjct: 802 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 858 Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223 PGP GP E G+ + + DP P A +GPAGL + ++ P ++ Sbjct: 859 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 916 Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283 EG PG PG+ S GP I PP R P A GE Sbjct: 917 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 962 Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339 VP G++G V+GP+ P G G K G P G Sbjct: 963 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 1007 Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381 G + PP P P+ VG G + EP P Sbjct: 1008 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1047 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 53.9 bits (128), Expect = 3e-07 Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%) Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71 +GP G A PGA GH G R G G G P Sbjct: 1006 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1058 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129 E+G G G PG P G + AD P PP V G P +G Sbjct: 1059 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1109 Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186 + GS I + V GP RG Q GP PGP GP ++ +G+ + Sbjct: 1110 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1162 Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243 F DP P GP G D D D G +PGSP G+ Sbjct: 1163 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1207 Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294 G R+ +G P I P + PV G+ L+ + V Sbjct: 1208 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1267 Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351 G++G RP +G A GP+ P G G + K +G P L L G G++ Sbjct: 1268 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1325 Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399 P P P G +G+ G S P PK + P G K + Sbjct: 1326 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1385 Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453 P + + LP Q P+ SV D P AP G + S +L Sbjct: 1386 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1443 Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490 R + + +G P HP P+ + QGC R Sbjct: 1444 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1489 Score = 41.6 bits (96), Expect = 0.002 Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP G PG+P G DL G R G G T P + Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 428 Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134 +GR G G PG P G D L E + QG P P G + D Sbjct: 429 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 487 Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194 E+GP RG S GP + P PG + +G K L Q +P Sbjct: 488 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 540 Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241 P +G G + LP + I ++G Q KPG P PG Sbjct: 541 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 578 Score = 41.6 bits (96), Expect = 0.002 Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72 GPEG + T PG P G L G G+ KG GF S E + Sbjct: 662 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 721 Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121 + E+G GQ G G A GGD E + P G Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 780 Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168 P P+G D L P RG + P P + GP+ Sbjct: 781 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 837 Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223 PGP GP E G+ + + DP P A +GPAGL + ++ P ++ Sbjct: 838 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 895 Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283 EG PG PG+ S GP I PP R P A GE Sbjct: 896 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 941 Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339 VP G++G V+GP+ P G G K G P G Sbjct: 942 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 986 Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381 G + PP P P+ VG G + EP P Sbjct: 987 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1026 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 53.9 bits (128), Expect = 3e-07 Identities = 131/526 (24%), Positives = 172/526 (32%), Gaps = 91/526 (17%) Query: 14 LGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGK--GESGFTDPESFSFESES 71 +GP G A PGA GH G R G G G P Sbjct: 1113 IGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSG------- 1165 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQ--GHPSPEGATA 129 E+G G G PG P G + AD P PP V G P +G Sbjct: 1166 ---EKGETGDVGPMGPPGPPGPRGPAGPNG----ADGPQG--PPGGVGNLGPPGEKGEPG 1216 Query: 130 K-GSTDIWADLEV-GPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRL 186 + GS I + V GP RG Q GP PGP GP ++ +G+ + Sbjct: 1217 ESGSPGIQGEPGVKGP--RGERGEKGESGQPGEPGP-----PGPKGPTGDDGPKGNPGPV 1269 Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDT--- 243 F DP P GP G D D D G +PGSP G+ Sbjct: 1270 GFPGDPGPPGEGGPRG---QDGAKGDRGED------------GEPGQPGSPGPTGENGPP 1314 Query: 244 --------CGRRSFHRRESYLQVQG-PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMV 294 G R+ +G P I P + PV G+ L+ + V Sbjct: 1315 GPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGKPGPDGLRGLPGSV 1374 Query: 295 WGKRGVRPSCSG-AAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-ALRGAFPAWGQRLSAV 351 G++G RP +G A GP+ P G G + K +G P L L G G++ Sbjct: 1375 -GQQG-RPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPGEQGEKGDRG 1432 Query: 352 PPDPASFPPVSG-VGLLGKS-----------VRPKEPKHSSPGKKPAGRKTRESQAAARE 399 P P P G +G+ G S P PK + P G K + Sbjct: 1433 LPGPQGSPGQKGEMGIPGASGPIGPGGPPGLPGPAGPKGAKGATGPGGPKGEKGVQGPPG 1492 Query: 400 DNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGD---PNIRAPQVLGTSQP---SAFTL 453 P + + LP Q P+ SV D P AP G + S +L Sbjct: 1493 HPGPPGEVI--QPLPIQMPKKTRRSVDGSRLMQEDEAIPTGGAPGSPGGLEEIFGSLDSL 1550 Query: 454 RRLVPRCHASSGDWQPPV---------HPPRPERQQQPPGAQGCPR 490 R + + +G P HP P+ + QGC R Sbjct: 1551 REEIEQMRRPTGTQDSPARTCQDLKLCHPELPDGEYWVDPNQGCAR 1596 Score = 41.6 bits (96), Expect = 0.002 Identities = 62/229 (27%), Positives = 77/229 (33%), Gaps = 35/229 (15%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP G PG+P G DL G R G G T P + Sbjct: 490 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPR-------GPQGLTGPPG-------KAG 535 Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134 +GR G G PG P G D L E + QG P P G + D Sbjct: 536 RRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGH-RGDTGAQGLPGPPGEDGERGDD 594 Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194 E+GP RG S GP + P PG + +G K L Q +P Sbjct: 595 G----EIGP--RGLPGESGPRGLLGPKGPPGIPGP-PGVRGMDGPQGPKGSLGPQGEPGP 647 Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIIST--KEGSQAKPGSPKKPG 241 P +G G + LP + I ++G Q KPG P PG Sbjct: 648 PGQQGTPG-----------TQGLPGPQGAIGPHGEKGPQGKPGLPGMPG 685 Score = 41.6 bits (96), Expect = 0.002 Identities = 102/402 (25%), Positives = 129/402 (32%), Gaps = 72/402 (17%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72 GPEG + T PG P G L G G+ KG GF S E + Sbjct: 769 GPEGPKGRTGPTGDPGPPGLMGEKGKLGVPGLPGYPGRQGPKGSLGFPGFPGASGEKGAR 828 Query: 73 LI--------EQGRVVLWGQEGRPGTPVDDQA---GGGDYSFYLADEPATIMPPSSVQGH 121 + E+G GQ G G A GGD E + P G Sbjct: 829 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERG-LPGPQGPNGF 887 Query: 122 PSPEGATAKGSTDIWADLEVGPSWRGALS-------PSPG-----EWQQASAGPL-HLSV 168 P P+G D L P RG + P P + GP+ Sbjct: 888 PGPKGPPGPPGKD---GLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPMGERGH 944 Query: 169 PGP-GPAWENPERGSKSRLSFQVDPQQPSA---EGPAGLNTDDSD-SADESSDLPVIRVI 223 PGP GP E G+ + + DP P A +GPAGL + ++ P ++ Sbjct: 945 PGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLK-- 1002 Query: 224 ISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELD 283 EG PG PG+ S GP I PP R P A GE Sbjct: 1003 --GNEGPSGPPGPAGSPGERGAAGS----------GGP--IGPPGRPGPQGPPGAAGEKG 1048 Query: 284 VPSLKKMQSMVWGKRGVRPSCSGAAVRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339 VP G++G V+GP+ P G G K G P G Sbjct: 1049 VP----------GEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDP-----G 1093 Query: 340 AFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSP 381 G + PP P P+ VG G + EP P Sbjct: 1094 QKGTKGNKGEHGPPGPPG--PIGPVGQPGAAGADGEPGARGP 1133 >gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f [Homo sapiens] Length = 1412 Score = 48.5 bits (114), Expect = 1e-05 Identities = 97/420 (23%), Positives = 144/420 (34%), Gaps = 88/420 (20%) Query: 12 AGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE- 70 +G P + A+T +G + G+ +S D S S E++ Sbjct: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212 Query: 71 ----SELIEQGRVVLWGQEGRPG---TPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS 123 SE I Q R +G PG TP G S A +P SS + S Sbjct: 213 EVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 272 Query: 124 PEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSK 183 E A + + + G+ Q A PA E+P +G+ Sbjct: 273 EEETPAAKAL--------------LQAKASGKTSQVGAAS--------APAKESPRKGAA 310 Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKKPGD 242 + P A+ AG +DS S+ E SD S +E +QAKP S K P Sbjct: 311 PAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKAPQV 359 Query: 243 TCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302 S +ES + P +PPR+ P + VG+ + S + Sbjct: 360 RAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE---------- 404 Query: 303 SCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362 R L A + K L +P++ PAS Sbjct: 405 --------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS---TM 435 Query: 363 GVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ L Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 447 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 506 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 554 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 555 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 594 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 595 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 647 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 648 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 701 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 702 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 753 Query: 471 VHPPR 475 V P+ Sbjct: 754 VRNPQ 758 >gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b [Homo sapiens] Length = 1411 Score = 48.5 bits (114), Expect = 1e-05 Identities = 97/420 (23%), Positives = 144/420 (34%), Gaps = 88/420 (20%) Query: 12 AGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE- 70 +G P + A+T +G + G+ +S D S S E++ Sbjct: 153 SGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDV 212 Query: 71 ----SELIEQGRVVLWGQEGRPG---TPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS 123 SE I Q R +G PG TP G S A +P SS + S Sbjct: 213 EVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDS 272 Query: 124 PEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSK 183 E A + + + G+ Q A PA E+P +G+ Sbjct: 273 EEETPAAKAL--------------LQAKASGKTSQVGAAS--------APAKESPRKGAA 310 Query: 184 SRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKKPGD 242 + P A+ AG +DS S+ E SD S +E +QAKP S K P Sbjct: 311 PAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKAPQV 359 Query: 243 TCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRP 302 S +ES + P +PPR+ P + VG+ + S + Sbjct: 360 RAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE---------- 404 Query: 303 SCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362 R L A + K L +P++ PAS Sbjct: 405 --------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS---TM 435 Query: 363 GVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ L Sbjct: 436 GMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSL 495 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 447 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 505 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 506 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 554 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 555 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 594 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 595 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 647 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 648 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 701 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 702 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 753 Query: 471 VHPPR 475 V P+ Sbjct: 754 VRNPQ 758 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 48.1 bits (113), Expect = 2e-05 Identities = 121/503 (24%), Positives = 163/503 (32%), Gaps = 102/503 (20%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--------KGESGFT-DPESF 65 G +G A +PG P G GG KG KG++G +P Sbjct: 395 GAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPV 454 Query: 66 SFESE-SELIEQGRVVLWGQEGRPGTP--VDDQAGGGDYSFYLADEPATIMPPSSVQGHP 122 + E+G+ G+ G G P ++ G G F AD A P+ +G P Sbjct: 455 GVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSP 514 Query: 123 SPEGATAKGST-DIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERG 181 P G KGS + E G L+ SPG S GP + P PGPA ++ G Sbjct: 515 GPAGP--KGSPGEAGRPGEAGLPGAKGLTGSPG-----SPGPDGKTGP-PGPAGQDGRPG 566 Query: 182 SKSRLSFQVDPQQPSAEGPAGLN--TDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKK 239 P P A G AG+ +A E K G + PG P Sbjct: 567 P---------PGPPGARGQAGVMGFPGPKGAAGEPG-----------KAGERGVPGPPGA 606 Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVW---- 295 G ++ QG PP P ER G P + + Sbjct: 607 VGPA-------GKDGEAGAQG-----PPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGE 654 Query: 296 ----GKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAV 351 G++GV P GA P P G G + ++ ++G P PA + + Sbjct: 655 AGKPGEQGV-PGDLGA----PGPSGARGERGFPGERGVQGPPG-------PAGPRGANGA 702 Query: 352 PPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKK-----PAGRKTRESQAAAREDNDPNRD 406 P + + G G P PG++ P + R D P +D Sbjct: 703 PGNDGAKGDAGAPGAPGSQGAP--GLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKD 760 Query: 407 EVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGD 466 V P P +GE G S P+ T R P GD Sbjct: 761 GVRGLTGPIGPPGPAGAPGDKGE-------------SGPSGPAGPTGARGAP------GD 801 Query: 467 WQPPVHPPRPERQQQPPGAQGCP 489 P PP P PPGA G P Sbjct: 802 RGEP-GPPGPAGFAGPPGADGQP 823 Score = 47.0 bits (110), Expect = 4e-05 Identities = 94/373 (25%), Positives = 126/373 (33%), Gaps = 60/373 (16%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESESE 72 GP G + A + G P GH G + G KGE G + + Sbjct: 245 GPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG----APGQ 300 Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT-AKG 131 + +G L G+ GRPG P A G D + A P P+ G P GA AKG Sbjct: 301 MGPRG---LPGERGRPGAPGPAGARGNDGATGAAGPPG----PTGPAGPPGFPGAVGAKG 353 Query: 132 STDIWADLEVGPSW-RGALSPSPGEWQQASAGPLHLSVP--GPGPAWENPERGSKSRLSF 188 E GP RG+ P + GP + P PG + +G+ Sbjct: 354 --------EAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGI 405 Query: 189 QVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRS 248 P P A GP+G +G+ +PG+P GDT + Sbjct: 406 AGAPGFPGARGPSGPQGPGGPPG---------------PKGNSGEPGAPGSKGDTGAKGE 450 Query: 249 FHRRESYLQVQGPLLI-SPPRRLTPVVERPAVGELDVPSLKKMQSMVW--GKRGVRPSCS 305 GP+ + PP +R A GE L G RG + Sbjct: 451 ----------PGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG 500 Query: 306 GAAVRGPL-PRGTLGRKVAQEKKSLEGAP-ELALRGAFPAWGQRLSAVPPDPASFPPVSG 363 A +GP RG+ G + G P E L GA G + PD + PP Sbjct: 501 VAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSP-GSPGPDGKTGPP--- 556 Query: 364 VGLLGKSVRPKEP 376 G G+ RP P Sbjct: 557 -GPAGQDGRPGPP 568 Score = 42.4 bits (98), Expect = 0.001 Identities = 117/476 (24%), Positives = 150/476 (31%), Gaps = 88/476 (18%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE-- 68 R GP G G P G+ G +GK GKG G T P E Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP-AGKEGGKGPRGETGPAGRPGEVG 923 Query: 69 ---SESELIEQGRVVLWGQEGRPGTP----VDDQAGGGDYSFYLADEPATIMP-PSSVQG 120 E+G G G PGTP + Q G + +P PS G Sbjct: 924 PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPG 983 Query: 121 HPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPG----PGPAWE 176 P GA+ + GP L+ PGE + A P PG PG + Sbjct: 984 KQGPSGASGERGPP-------GPMGPPGLAGPPGESGREGA-PGAEGSPGRDGSPGAKGD 1035 Query: 177 NPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGS 236 E G P P GPAG + D ++ PV V G Q G Sbjct: 1036 RGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGD 1095 Query: 237 PKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWG 296 + G+ G R + +QGP PP +P + P Sbjct: 1096 KGETGEQ-GDRGIKGHRGFSGLQGP--PGPPG--SPGEQGP------------------- 1131 Query: 297 KRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAP-ELALRGAFPAWGQRLSAVPPD 354 SGA+ GP PRG G A K L G P + G G PP Sbjct: 1132 --------SGAS--GPAGPRGPPGSAGAPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPG 1181 Query: 355 PASFPPVSGVGLLG--KSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 412 P P G G S P+ P+ + GR R A D D D ++ Sbjct: 1182 PPGPPGPPGPPSAGFDFSFLPQPPQEKA---HDGGRYYRADDANVVRDRDLEVDTTLKS- 1237 Query: 413 LPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQ 468 S NIR+P+ G+ + A T R L CH+ DW+ Sbjct: 1238 -----------------LSQQIENIRSPE--GSRKNPARTCRDL-KMCHS---DWK 1270 Score = 34.3 bits (77), Expect = 0.28 Identities = 94/384 (24%), Positives = 117/384 (30%), Gaps = 41/384 (10%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKG--KGKGESGFTDPESFSFE 68 R G G + A +PGAP G G+R G KG+ G P+ Sbjct: 697 RGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGS 756 Query: 69 SESELIE--QGRVVLWGQEGRPGT-----------PVDDQAGGGDYSFYLADEPATIMPP 115 + + G + G G PG P + GD PA P Sbjct: 757 PGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGP 816 Query: 116 SSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAW 175 G P +G D A + GP + PG A + GP Sbjct: 817 PGADGQPGAKGEPG----DAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPG 872 Query: 176 ENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPG 235 G+ R V P PS G AG + E P + + G PG Sbjct: 873 ATGFPGAAGR----VGPPGPS--GNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPG 926 Query: 236 SPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAV-GELDVPSLKKMQSMV 294 P G+ G GP I+ R VV P GE P L S Sbjct: 927 PPGPAGEK-GSPGADGPAGAPGTPGPQGIAGQR---GVVGLPGQRGERGFPGLPG-PSGE 981 Query: 295 WGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAP----ELALRGAFPAWGQRLSA 350 GK+G PS + P P G G + EGAP G+ A G R Sbjct: 982 PGKQG--PSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGET 1039 Query: 351 VPPDPASFPPVSG----VGLLGKS 370 P P P G VG GKS Sbjct: 1040 GPAGPPGAPGAPGAPGPVGPAGKS 1063 >gi|4504733 insulin receptor substrate 4 [Homo sapiens] Length = 1257 Score = 46.6 bits (109), Expect = 5e-05 Identities = 66/275 (24%), Positives = 101/275 (36%), Gaps = 31/275 (11%) Query: 13 GLGPEGGEQ-AGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 G G GG++ G H + G GDGHG GG+ SG GKG G +D + +S Sbjct: 555 GHGSGGGQRPGGGHGSGGGQGPGDGHGSG---GGKNSGGGKGSGSGKGSDGDGERGKSLK 611 Query: 72 ELIEQGRVVLWGQEGRP-------------GTPVDDQAGGGDYSFYLADEPAT--IMPPS 116 + G++ Q+ P GT ++GG ++ D AT Sbjct: 612 KRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAK 671 Query: 117 SVQGHPSPEGATAKG-----STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGP 171 V+ PEGA A+G + D D P G +P P ++S Sbjct: 672 EVKDAEIPEGA-ARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKK 730 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 + +P S+ + P A P D++ D+S D + G+ Sbjct: 731 RHS-RSPFEDSRGYMMMFPRVSPPPAPSPP--KAPDTNKEDDSKDNDSESDYMFMAPGAG 787 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISP 266 A P +P+ P +S+ SY + P SP Sbjct: 788 AIPKNPRNPQGGSSSKSW---SSYFSLPNPFRSSP 819 >gi|32140760 collagen, type XXVII, alpha 1 [Homo sapiens] Length = 1860 Score = 46.2 bits (108), Expect = 7e-05 Identities = 82/278 (29%), Positives = 96/278 (34%), Gaps = 58/278 (20%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESE 70 R LGPEG E PGAP +G F G R G KGE G DP Sbjct: 939 RGQLGPEGDE---GPMGPPGAPGLEGQPGRKGFPG-RPGLDGVKGEPG--DPGR-----P 987 Query: 71 SELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS-PEGATA 129 + EQG + G G PG V ++ G P + P GHP P G Sbjct: 988 GPVGEQGFMGFIGLVGEPGI-VGEKGDRGMMG------PPGVPGPKGSMGHPGMPGGMGT 1040 Query: 130 KGSTDIWADLEVGPSWR-GALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRLS 187 G E GP G+ P + GP GP GPA E RG K Sbjct: 1041 PG--------EPGPQGPPGSRGPPGMRGAKGRRGPR-----GPDGPAGEQGSRGLKGPPG 1087 Query: 188 FQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRR 247 Q P +P +G AG E L GS+ PG P P G + Sbjct: 1088 PQGRPGRPGQQGVAG----------ERGHL-----------GSRGFPGIP-GPSGPPGTK 1125 Query: 248 SFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVP 285 QGP I PP + P AVGE +P Sbjct: 1126 GLPGEPGPQGPQGP--IGPPGEMGPKGPPGAVGEPGLP 1161 Score = 38.1 bits (87), Expect = 0.020 Identities = 121/511 (23%), Positives = 165/511 (32%), Gaps = 113/511 (22%) Query: 11 RAGLGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFE 68 R GP+G GE+ P G + +SGK KG +G + + Sbjct: 1206 RGDPGPDGEHGEKGQEGLMGEDGPPGPPGVTGVRGPEGKSGKQGEKGRTGAKGAKGY--- 1262 Query: 69 SESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGAT 128 + +L E G + G G PGTP + G + P+ G +G Sbjct: 1263 -QGQLGEMG---VPGDPGPPGTPGPKGSRGS-------------LGPTGAPGRMGAQGEP 1305 Query: 129 AKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGP----GPAWENPERGSKS 184 D + VGP G P + +Q G PGP GP + +RG Sbjct: 1306 GLAGYDGHKGI-VGPL--GPPGPKGEKGEQGEDGKAE-GPPGPPGDRGPVGDRGDRGEPG 1361 Query: 185 RLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTC 244 DP P EG GL K G Q +PG P Sbjct: 1362 ------DPGYPGQEGVQGLR---------------------GKPGQQGQPGHP------- 1387 Query: 245 GRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSM--VWGKRGV-- 300 G R + + +GP + G+ P + +Q + + G RGV Sbjct: 1388 GPRGWPGPKGSKGAEGP--------------KGKQGKAGAPGRRGVQGLQGLPGPRGVVG 1433 Query: 301 RPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 R G A LP G G+ Q ++ +G P G G+R + P A P Sbjct: 1434 RQGLEGIAGPDGLP-GRDGQAGQQGEQGDDGDP-----GPMGPAGKRGN---PGVAGLPG 1484 Query: 361 VSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPE 419 G G G+S P + PGK R T +P P P Sbjct: 1485 AQGPPGFKGESGLPGQ--LGPPGK----RGTEGRTGLPGNQGEPGSKGQPGDSGEMGFPG 1538 Query: 420 LISLSVRRGEYS----SGDPNIRAPQVLGTSQPSAFTLRRLVPR-------CHASSGDW- 467 + L +G G R P L + L L P S GDW Sbjct: 1539 MAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGILGPSGLPGPKGDKGSRGDWG 1598 Query: 468 -QPPVHPPRPERQQQPPGAQGCPRCILLQRE 497 Q P PP P + PPG G P I LQ++ Sbjct: 1599 LQGPRGPPGPRGRPGPPGPPGGP--IQLQQD 1627 Score = 37.7 bits (86), Expect = 0.025 Identities = 89/378 (23%), Positives = 131/378 (34%), Gaps = 83/378 (21%) Query: 15 GPEG--GEQA--GAHTASPGAP--------RGD-GHGRDLNFGGQRSGKG-KGK----GE 56 GP+G GEQ G PG P RGD G D + GQ +G +GK G+ Sbjct: 1324 GPKGEKGEQGEDGKAEGPPGPPGDRGPVGDRGDRGEPGDPGYPGQEGVQGLRGKPGQQGQ 1383 Query: 57 SGFTDPESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPS 116 G P + S+ E + G++G+ G P G Sbjct: 1384 PGHPGPRGWPGPKGSKGAEGPK----GKQGKAGAPGRRGVQG------------------ 1421 Query: 117 SVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWE 176 +QG P P G + + A + P G + GP+ GP Sbjct: 1422 -LQGLPGPRGVVGRQGLEGIAGPDGLPGRDGQAGQQGEQGDDGDPGPM-----GPAGKRG 1475 Query: 177 NPE----RGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQA 232 NP G++ F+ + P GP G + + LP G+Q Sbjct: 1476 NPGVAGLPGAQGPPGFKGESGLPGQLGPPGKR-----GTEGRTGLP----------GNQG 1520 Query: 233 KPGSPKKPGDTCGRRSFHRRESYLQVQGP------LLISPPRRLTPVVERPA-VGELDVP 285 +PGS +PGD+ G F +GP I PR ++ + VG L + Sbjct: 1521 EPGSKGQPGDS-GEMGFPGMAGLFGPKGPPGDIGFKGIQGPRGPPGLMGKEGIVGPLGIL 1579 Query: 286 SLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAP----ELALRGAF 341 S + G +G + S ++G PRG G + G P + L AF Sbjct: 1580 G----PSGLPGPKGDKGSRGDWGLQG--PRGPPGPRGRPGPPGPPGGPIQLQQDDLGAAF 1633 Query: 342 PAWGQRLSAVPPDPASFP 359 W A+ P+ S+P Sbjct: 1634 QTWMDTSGALRPESYSYP 1651 Score = 30.4 bits (67), Expect = 4.1 Identities = 124/528 (23%), Positives = 172/528 (32%), Gaps = 89/528 (16%) Query: 15 GPEGGE-QAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKG--KGESGFTDPESFSFESES 71 GP G + Q G SPG DG D+ G G KG G+ P E Sbjct: 667 GPPGAKGQKGDPGLSPGKAH-DGAKGDMGLPGLSGNPGPPGRKGHKGYPGPAGHPGEQGQ 725 Query: 72 ELIE--QGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA 129 E G G++G PG PV D G + + +G P G Sbjct: 726 PGPEGSPGAKGYPGRQGLPG-PVGDPGPKGSRGYIGLPGLFGLPGSDGERGLPGVPGKRG 784 Query: 130 KGSTDIWADL--EVGPSWRGALSPSPGEWQQASAGPLHLSVPGP-------------GPA 174 K + + E GP L +PGE L +PGP GP Sbjct: 785 KMGMPGFPGVFGERGPP---GLDGNPGE----------LGLPGPPGVPGLIGDLGVLGPI 831 Query: 175 WENPERGSKSRLSFQVDPQ---QPSAEGPAGLNTDDSDSADESSDL------------PV 219 +G K + +P +G G++ D D+ S P+ Sbjct: 832 GYPGPKGMKGLMGSVGEPGLKGDKGEQGVPGVSGDPGFQGDKGSQGLPGFPGARGKPGPL 891 Query: 220 IRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPR-RLTPVVERPA 278 +V G PG PGD G + E G + PR +L P + Sbjct: 892 GKVGDKGSIGFPGPPGPEGFPGDI-GPPGDNGPEGMKGKPGARGLPGPRGQLGPEGDEGP 950 Query: 279 VGELDVPSLKKMQSMVWGKRGV--RPSCSGAAVRG----PLPRGTLGRKVAQEKKSLEGA 332 +G P L+ G++G RP G V+G P G +G + L G Sbjct: 951 MGPPGAPGLEGQP----GRKGFPGRPGLDG--VKGEPGDPGRPGPVGEQGFMGFIGLVGE 1004 Query: 333 PELALRGAFPAWGQRLSAVPPD-PASFPPVSGVGLLGKSVRPKEPKHSSP--GKKPAGRK 389 P G G R PP P + G+ G P EP P + P G + Sbjct: 1005 P-----GIVGEKGDRGMMGPPGVPGPKGSMGHPGMPGGMGTPGEPGPQGPPGSRGPPGMR 1059 Query: 390 TRESQAAAREDNDPNRDE-------VPRAQLPTQKPELISLSVRRGEYSS-GDPNIRAPQ 441 + + R + P ++ P Q +P ++ RG S G P I P Sbjct: 1060 GAKGRRGPRGPDGPAGEQGSRGLKGPPGPQGRPGRPGQQGVAGERGHLGSRGFPGIPGP- 1118 Query: 442 VLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQQPPGAQGCP 489 S P + +P G Q P+ PP + PPGA G P Sbjct: 1119 ----SGPPG---TKGLPGEPGPQGP-QGPIGPPGEMGPKGPPGAVGEP 1158 >gi|27262667 colony stimulating factor 1 isoform a precursor [Homo sapiens] Length = 554 Score = 45.4 bits (106), Expect = 1e-04 Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 67/300 (22%) Query: 167 SVPGPGPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIIST 226 ++P PA +P + P PS AGL +DS+ + SS LP + + + Sbjct: 196 AIPSSDPASVSPHQ-----------PLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTV 244 Query: 227 KEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPS 286 GS + + P TC +SF E+ + + SP RP+VG + P Sbjct: 245 DPGSAKQ----RPPRSTC--QSFEPPETPVVKDSTIGGSPQ-------PRPSVGAFN-PG 290 Query: 287 LKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346 ++ + G V SG A P+P+GT + S G + A P+ Sbjct: 291 MEDILDSAMGTNWVPEEASGEASEIPVPQGT------ELSPSRPGGGSMQTEPARPS--N 342 Query: 347 RLSAVPPDPASFP---PVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDP 403 LSA P PAS P G V P P P +KT A R+ +P Sbjct: 343 FLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTP--QKTDHPSALLRDPPEP 400 Query: 404 NRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHAS 463 G P I + + G S PS + + + R H+S Sbjct: 401 -----------------------------GSPRISSLRPQGLSNPSTLSAQPQLSRSHSS 431 >gi|27262661 colony stimulating factor 1 isoform a precursor [Homo sapiens] Length = 554 Score = 45.4 bits (106), Expect = 1e-04 Identities = 72/300 (24%), Positives = 107/300 (35%), Gaps = 67/300 (22%) Query: 167 SVPGPGPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIIST 226 ++P PA +P + P PS AGL +DS+ + SS LP + + + Sbjct: 196 AIPSSDPASVSPHQ-----------PLAPSMAPVAGLTWEDSEGTEGSSLLPGEQPLHTV 244 Query: 227 KEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPS 286 GS + + P TC +SF E+ + + SP RP+VG + P Sbjct: 245 DPGSAKQ----RPPRSTC--QSFEPPETPVVKDSTIGGSPQ-------PRPSVGAFN-PG 290 Query: 287 LKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346 ++ + G V SG A P+P+GT + S G + A P+ Sbjct: 291 MEDILDSAMGTNWVPEEASGEASEIPVPQGT------ELSPSRPGGGSMQTEPARPS--N 342 Query: 347 RLSAVPPDPASFP---PVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDP 403 LSA P PAS P G V P P P +KT A R+ +P Sbjct: 343 FLSASSPLPASAKGQQPADVTGTALPRVGPVRPTGQDWNHTP--QKTDHPSALLRDPPEP 400 Query: 404 NRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHAS 463 G P I + + G S PS + + + R H+S Sbjct: 401 -----------------------------GSPRISSLRPQGLSNPSTLSAQPQLSRSHSS 431 >gi|207113162 Treacher Collins-Franceschetti syndrome 1 isoform e [Homo sapiens] Length = 1451 Score = 45.1 bits (105), Expect = 2e-04 Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%) Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127 E ESE E+G +E GT +A A PA P P + Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324 Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180 T E S S S E A A G PA E+P + Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239 G+ + P A+ AG +DS S+ E SD S +E +QAKP S K Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433 Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299 P S +ES + P +PPR+ P + VG+ + S + Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481 Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 R L A + K L +P++ PAS Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510 Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569 Query: 418 PEL 420 L Sbjct: 570 KSL 572 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830 Query: 471 VHPPR 475 V P+ Sbjct: 831 VRNPQ 835 >gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d [Homo sapiens] Length = 1488 Score = 45.1 bits (105), Expect = 2e-04 Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%) Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127 E ESE E+G +E GT +A A PA P P + Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324 Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180 T E S S S E A A G PA E+P + Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239 G+ + P A+ AG +DS S+ E SD S +E +QAKP S K Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433 Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299 P S +ES + P +PPR+ P + VG+ + S + Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481 Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 R L A + K L +P++ PAS Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510 Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569 Query: 418 PEL 420 L Sbjct: 570 KSL 572 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830 Query: 471 VHPPR 475 V P+ Sbjct: 831 VRNPQ 835 >gi|57164977 Treacher Collins-Franceschetti syndrome 1 isoform a [Homo sapiens] Length = 1450 Score = 45.1 bits (105), Expect = 2e-04 Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%) Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127 E ESE E+G +E GT +A A PA P P + Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324 Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180 T E S S S E A A G PA E+P + Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239 G+ + P A+ AG +DS S+ E SD S +E +QAKP S K Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433 Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299 P S +ES + P +PPR+ P + VG+ + S + Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481 Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 R L A + K L +P++ PAS Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510 Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569 Query: 418 PEL 420 L Sbjct: 570 KSL 572 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830 Query: 471 VHPPR 475 V P+ Sbjct: 831 VRNPQ 835 >gi|57164979 Treacher Collins-Franceschetti syndrome 1 isoform c [Homo sapiens] Length = 958 Score = 45.1 bits (105), Expect = 2e-04 Identities = 88/363 (24%), Positives = 123/363 (33%), Gaps = 67/363 (18%) Query: 68 ESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGA 127 E ESE E+G +E GT +A A PA P P + Sbjct: 267 EEESESSEEGSES--EEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAG 324 Query: 128 TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASA-------GPLHLSVPGPGPAWENPER 180 T E S S S E A A G PA E+P + Sbjct: 325 AVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRK 384 Query: 181 GSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEG-SQAKPGSPKK 239 G+ + P A+ AG +DS S+ E SD S +E +QAKP S K Sbjct: 385 GAAPAPPGKTGPAVAKAQ--AGKREEDSQSSSEESD--------SEEEAPAQAKP-SGKA 433 Query: 240 PGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG 299 P S +ES + P +PPR+ P + VG+ + S + Sbjct: 434 PQVRAA--SAPAKESPRKGAAP---APPRKTGPAAAQVQVGKQEEDSRSSSEE------- 481 Query: 300 VRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFP 359 R L A + K L +P++ PAS Sbjct: 482 -----------SDSDREALAAMNAAQVKPLGKSPQVK------------------PAS-- 510 Query: 360 PVSGVGLLGKSVRPKEPKHSSPGKKPA--GRKTRESQAAAREDNDPNRDEVPRAQLPTQK 417 G+G LGK P P P A G+ +S++++ E +D + EVP A P Q+ Sbjct: 511 -TMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQE 569 Query: 418 PEL 420 L Sbjct: 570 KSL 572 Score = 41.6 bits (96), Expect = 0.002 Identities = 76/365 (20%), Positives = 125/365 (34%), Gaps = 55/365 (15%) Query: 113 MPPSSVQGHPSPEGATAKGSTDIWADLEVGP-SWRGALSPSPGEWQQASAGPLHLSVPGP 171 +PP V G +P K D + E S G + + Q+ S G + + P Sbjct: 524 VPPGKV-GPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTS 582 Query: 172 GPAWENPERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQ 231 PA P++ ++ QV ++P D+S+S++ESSD + +Q Sbjct: 583 SPAKGPPQKAGP--VAVQVKAEKPM---------DNSESSEESSDSADSEEAPAAMTAAQ 631 Query: 232 AKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQ 291 AKP C +++ ++P R T + Sbjct: 632 AKPALKIPQTKACPKKT--------NTTASAKVAPVRVGTQAPRKAGT------------ 671 Query: 292 SMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALR-GAFPAWGQRLSA 350 P+ S AV G R ++E S E LA+ G + G+ L Sbjct: 672 -------ATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQV 724 Query: 351 VPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPR 410 A+ PV G LG+ P P + P + +E ++ E++D Sbjct: 725 ----KAASVPVK--GSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASP 778 Query: 411 AQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPP 470 AQ+ T SV++ + + RAP GT + S +PP Sbjct: 779 AQVKT--------SVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPP 830 Query: 471 VHPPR 475 V P+ Sbjct: 831 VRNPQ 835 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 45.1 bits (105), Expect = 2e-04 Identities = 90/416 (21%), Positives = 132/416 (31%), Gaps = 68/416 (16%) Query: 109 PATIMPPSSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSV 168 PAT P +G P+P AT PS +G L+ P + + P ++ Sbjct: 1255 PATPPP----KGAPTPPAATP-------------PSLKGGLATPP---HKGAPNPAVVTP 1294 Query: 169 PGP--GPAWENPERGSKSRLSFQVDPQ-QPSAEGPAGLNTDDSDSADESSDLPVIRVIIS 225 P P GPA P+ + P+ P P G T + + P + Sbjct: 1295 PSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354 Query: 226 TKEGSQAKPGS---PKKPGDTCGRRSFHRRESYLQVQGPLLISP-------------PRR 269 + +G P S P P T + +GP + SP P++ Sbjct: 1355 SSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKK 1414 Query: 270 L--TPVVER----PAVGELDVP-----SLKKMQSMVWGKRG-VRPSCSG----AAVRGPL 313 TPV P+ G+L P SLKK + K G PS G AV P Sbjct: 1415 APATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPS 1474 Query: 314 PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRP 373 P+ A ++ + +P+ A P L AV P P + P Sbjct: 1475 PK----EPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATP----SSRRDP 1526 Query: 374 KEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSG 433 P + KK + P+ + P P + P S + +S Sbjct: 1527 IAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS-----SKEASS 1581 Query: 434 DPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPRPERQQQPPGAQGCP 489 P + G P + V P V PP PE+ P +G P Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTP 1637 Score = 30.8 bits (68), Expect = 3.1 Identities = 50/208 (24%), Positives = 72/208 (34%), Gaps = 27/208 (12%) Query: 302 PSCSGAAVRGP-LPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPP 360 P+ G+A GP P G L V+ + S L+ +G+ + S PP P P Sbjct: 809 PTKKGSA--GPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPT 866 Query: 361 VSGVGLL---GKSVRPKE---------------PKHSSPGKKPAGRKTRESQAAAREDND 402 S V L G ++ PKE P +P + PA T S AR Sbjct: 867 PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926 Query: 403 PNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHA 462 P +P + P P + G P +P+ T + + P + Sbjct: 927 PK--GIPASPSPKGAP---TPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981 Query: 463 SSGDWQPP-VHPPRPERQQQPPGAQGCP 489 G PP PP P+ P +G P Sbjct: 982 PKGAPTPPAATPPSPKGGPATPSPKGAP 1009 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 43.1 bits (100), Expect = 6e-04 Identities = 103/424 (24%), Positives = 131/424 (30%), Gaps = 78/424 (18%) Query: 14 LGPEG--GEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESES 71 +GP G GE+ + +PG P G + G G KG+ GF P Sbjct: 1438 VGPPGKKGEKGDSEDGAPGLPGQPGSPGEQGPRGPPGAIGP-KGDRGFPGP----LGEAG 1492 Query: 72 ELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKG 131 E E+G G G PG A G P P+ QG G G Sbjct: 1493 EKGERGPPGPAGSRGLPGVAGRPGAKG----------PEGPPGPTGRQGEKGEPGRP--G 1540 Query: 132 STDIWADLEVGPSWR----GALSPSPGEWQQASAGPLHLSVPG-PGPAWENPERG----- 181 + GP G P Q GP L +PG PGP + +RG Sbjct: 1541 DPAVVGPAVAGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLT 1600 Query: 182 -------SKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKP 234 + DP +P GP G D + + +G + P Sbjct: 1601 GRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGE---------------KGDEGPP 1645 Query: 235 GSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGE--LDVPSLKKMQS 292 G P PG G R L P PV E+ G+ D + S Sbjct: 1646 GDPGLPG-KAGERG--------------LRGAPGVRGPVGEKGDQGDPGEDGRNGSPGSS 1690 Query: 293 MVWGKRGVRPSCSGAAVR------GPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQ 346 G RG P G R G +G G + + + +G P L GA G Sbjct: 1691 GPKGDRG-EPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDP--GLPGAPGERGI 1747 Query: 347 RLSAVPPDPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNR 405 PP P P V G G G P S KP AA + DP R Sbjct: 1748 EGFRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGR 1807 Query: 406 DEVP 409 D +P Sbjct: 1808 DGLP 1811 Score = 42.0 bits (97), Expect = 0.001 Identities = 108/446 (24%), Positives = 140/446 (31%), Gaps = 84/446 (18%) Query: 15 GPEGGEQAGAHTASPGAPRGDGH-GRDLNFGGQRSGKGKGKGESGFTDPESFSFESESEL 73 GP G A PGA G GR N G G KG G P Sbjct: 1287 GPPGSATAKGERGFPGADGRPGSPGRAGNPG--TPGAPGLKGSPGLPGPRG--------- 1335 Query: 74 IEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPS--SVQGHPSPEGATAKG 131 + G G +G PG P G G +P PP G P P G Sbjct: 1336 -DPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGDPGPRGPPGLP 1394 Query: 132 STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191 T + D + + GP PGPG P L Sbjct: 1395 GTAMKGD----------------KGDRGERGP-----PGPGEGGIAPGEPGLPGLPGSPG 1433 Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHR 251 PQ P GP G + DS D + LP + ++G + PG+ GD G Sbjct: 1434 PQGPV--GPPGKKGEKGDSEDGAPGLPG-QPGSPGEQGPRGPPGAIGPKGDR-GFPGPLG 1489 Query: 252 RESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRG--VRPSCSGAAV 309 +GP + R L V RP + P + G+ G P+ G AV Sbjct: 1490 EAGEKGERGPPGPAGSRGLPGVAGRPGAKGPEGPPGPTGRQGEKGEPGRPGDPAVVGPAV 1549 Query: 310 RGPLPR----GTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSG-V 364 GP G G + A + G P L L G P P P G + Sbjct: 1550 AGPKGEKGDVGPAGPRGATGVQGERGPPGLVLPG------------DPGPKGDPGDRGPI 1597 Query: 365 GLLGKSVRPKEPKHSSPGKK----------PAGRKTRESQAAAREDNDPNRDEVPRAQLP 414 GL G++ P + PG+K P G + R+ + + D P D Sbjct: 1598 GLTGRAGPPGD--SGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDEGPPGD-------- 1647 Query: 415 TQKPELISLSVRRGEYSSGDPNIRAP 440 P L + RG G P +R P Sbjct: 1648 ---PGLPGKAGERG--LRGAPGVRGP 1668 Score = 42.0 bits (97), Expect = 0.001 Identities = 62/218 (28%), Positives = 74/218 (33%), Gaps = 29/218 (13%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGD------GHGRDLNFGGQRSGKGKG--KGESGFTDP 62 R LGP+G A PG+P D G D+ F G R KG+ KG G Sbjct: 2580 RGLLGPQGQPGAAGIPGDPGSPGKDGVPGIRGEKGDVGFMGPRGLKGERGVKGACGLDGE 2639 Query: 63 ESFSFESESELIEQGRVVLWGQEGRPGTP-VDDQAGG----------GDYSFYLADEPAT 111 + + E GR L G +G G P V Q+G GD F P Sbjct: 2640 KG----DKGEAGPPGRPGLAGHKGEMGEPGVPGQSGAPGKEGLIGPKGDRGFDGQPGPKG 2695 Query: 112 IMPPSSVQGHPSPEGATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPG- 170 +G P G D A P G P + Q+ GP V G Sbjct: 2696 DQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSVGPRGPEGLQGQKGERGPPGERVVGA 2755 Query: 171 PGPAWENPERGSKSRLSFQVDPQQPSAE-GPAGLNTDD 207 PG ERG + R P P E G A L DD Sbjct: 2756 PGVPGAPGERGEQGR----PGPAGPRGEKGEAALTEDD 2789 Score = 37.7 bits (86), Expect = 0.025 Identities = 76/335 (22%), Positives = 102/335 (30%), Gaps = 73/335 (21%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP+G G P GR L G G SG P+ Sbjct: 2198 GPQGPSGLKGEPGETGPP-----GRGLTGPTGAVGLPGPPGPSGLVGPQG---------- 2242 Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPAT--IMPPSSVQGHPSPEGATAKGS 132 G G+ G+PG P D A G D P + + P +G P P GA + Sbjct: 2243 SPGLPGQVGETGKPGAPGRDGASGKDGDRGSPGVPGSPGLPGPVGPKGEPGPTGAPGQAV 2302 Query: 133 TDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDP 192 L +GA G+ +PGP RG K +P Sbjct: 2303 ----VGLPGAKGEKGAPGGLAGDLVGEPGAKGDRGLPGP--------RGEKGEAGRAGEP 2350 Query: 193 QQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRR 252 P +G G D +P GS PG P GD Sbjct: 2351 GDPGEDGQKGAPGPKGFKGDPGVGVP----------GSPGPPGPPGVKGD---------- 2390 Query: 253 ESYLQVQG----PLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAA 308 L + G P ++ P + P GE+ P G+RG+ Sbjct: 2391 ---LGLPGLPGAPGVVGFPGQTGP------RGEMGQPGPS-------GERGLAGPPGREG 2434 Query: 309 VRGPL----PRGTLGRKVAQEKKSLEGAPELALRG 339 + GPL P G++G A K +G P + L G Sbjct: 2435 IPGPLGPPGPPGSVGPPGASGLKGDKGDPGVGLPG 2469 Score = 35.8 bits (81), Expect = 0.097 Identities = 62/235 (26%), Positives = 74/235 (31%), Gaps = 66/235 (28%) Query: 15 GPEGGEQAGAHTASPG--APRGD----GHGRDLNFGGQRSGKGKG--KGESGFTDPESFS 66 GP G + A S G P+GD G D G R G GE G PE Sbjct: 2108 GPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLPGERGMAGPE--- 2164 Query: 67 FESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEG 126 G+ L G G PG PV G PA PS ++G P Sbjct: 2165 ----------GKPGLQGPRGPPG-PVGGHGDPGPPGAPGLAGPAGPQGPSGLKGEPG--- 2210 Query: 127 ATAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRL 186 E GP RG P+ G + L P PGP+ +GS Sbjct: 2211 -------------ETGPPGRGLTGPT---------GAVGLPGP-PGPSGLVGPQGSPGLP 2247 Query: 187 SFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPG 241 + +P A G G + D D GS PGSP PG Sbjct: 2248 GQVGETGKPGAPGRDGASGKDGD------------------RGSPGVPGSPGLPG 2284 Score = 32.0 bits (71), Expect = 1.4 Identities = 116/491 (23%), Positives = 160/491 (32%), Gaps = 70/491 (14%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQ--RSGKGKGKGESGFTDPESFSFESESE 72 GP G + PGA G G R G +GE G P S + Sbjct: 1773 GPPGLDGRSGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGP-SGPPGLPGK 1831 Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGG--GDYSFYLADEPATIMPPSSVQGHPSPEGATAK 130 E G+ L G+ G PG P +D G GD S +G P+G + Sbjct: 1832 PGEDGKPGLNGKNGEPGDPGEDGRKGEKGDSG------------ASGREGRDGPKG--ER 1877 Query: 131 GSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQV 190 G+ I + P G + P PG+ G G GP + E GSK Q Sbjct: 1878 GAPGILGP-QGPPGLPGPVGP-PGQGFPGVPG-------GTGPKGDRGETGSKGE---QG 1925 Query: 191 DPQQPSAEGPAGLNTDDSDSADESSDL--PVIRVIISTKEGSQAK----PGSPKKPGDTC 244 P + G G + + D E++ + +R I+ T + S P + P Sbjct: 1926 LPGERGLRGEPG-SVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDS 1984 Query: 245 GRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSC 304 G + +E + G ER G+ P + + G+RG P Sbjct: 1985 GEQGPPGKEGPIGFPG--------------ERGLKGDRGDPGPQGPPGLALGERG-PPGP 2029 Query: 305 SGAAVRGPLP--RGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVS 362 SG A P G GR + G RG G+R P P Sbjct: 2030 SGLAGEPGKPGIPGLPGRAGGVGEAGRPGE-----RGERGEKGERGEQGRDGPPGLPGTP 2084 Query: 363 G-VGLLGKSVRPKEPKHSSPGKK-PAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPEL 420 G G G V EP G++ P G K + + + D P D +P K + Sbjct: 2085 GPPGPPGPKVSVDEPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDR----GVPGIKGDR 2140 Query: 421 ISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHP--PRPER 478 R + + G P R + G R P GD PP P P Sbjct: 2141 GEPGPRGQDGNPGLPGERG--MAGPEGKPGLQGPRGPPGPVGGHGDPGPPGAPGLAGPAG 2198 Query: 479 QQQPPGAQGCP 489 Q P G +G P Sbjct: 2199 PQGPSGLKGEP 2209 Score = 30.0 bits (66), Expect = 5.3 Identities = 120/522 (22%), Positives = 155/522 (29%), Gaps = 89/522 (17%) Query: 15 GPEGGEQAGAHTASPG-------APRGD-GHGRDLNFGGQR-----SGKGKGKGESGFTD 61 GP G PG P+GD G + G+ SG KG+ G Sbjct: 1563 GPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKGDPGRPG 1622 Query: 62 PESFSFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSV--Q 119 P + +GR G++G G P D G L P P Q Sbjct: 1623 PPG-------PVGPRGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQ 1675 Query: 120 GHPSPEGATAKGSTDIWADLEVGPSW-RGALSPSPGEWQQASAGPLHLSVPGPGPAWENP 178 G P +G + GP RG P + GP PG + Sbjct: 1676 GDPGEDGRNGSPGSS-------GPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEG 1728 Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTK----------- 227 RG K DP P A G G+ + P +R K Sbjct: 1729 PRGPKG------DPGLPGAPGERGIEGFRGPPGPQGD--PGVRGPAGEKGDRGPPGLDGR 1780 Query: 228 EGSQAKPGS--PKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVP 285 G KPG+ P P G+ R+ ++G + P + +P GE P Sbjct: 1781 SGLDGKPGAAGPSGPNGAAGKAGDPGRDGLPGLRGEQGLPGPSGPPGLPGKP--GEDGKP 1838 Query: 286 SLKKMQSMVWGKRGVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPEL-------AL 337 L GK G +G G GR+ K GAP + L Sbjct: 1839 GLN-------GKNGEPGDPGEDGRKGEKGDSGASGREGRDGPKGERGAPGILGPQGPPGL 1891 Query: 338 RGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKE-PKHSSPGKKPAGRKTRES--- 393 G GQ VP G G+ P E PG P + E+ Sbjct: 1892 PGPVGPPGQGFPGVPGGTGPKGDRGETGSKGEQGLPGERGLRGEPGSVPNVDRLLETAGI 1951 Query: 394 QAAAREDNDPNRDEVPRAQLPTQKPELISLSVRRGEYSSGDPNIRAPQVLGTSQPSAFTL 453 +A+A + DE + LP PE RRG GD + P G P F Sbjct: 1952 KASALREIVETWDESSGSFLPV--PER-----RRG--PKGDSGEQGPP--GKEGPIGFPG 2000 Query: 454 RRLVPRCHASSGDWQPP------VHPPRPERQQQPPGAQGCP 489 R + G PP PP P PG G P Sbjct: 2001 ERGLKGDRGDPGPQGPPGLALGERGPPGPSGLAGEPGKPGIP 2042 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 42.4 bits (98), Expect = 0.001 Identities = 118/494 (23%), Positives = 152/494 (30%), Gaps = 110/494 (22%) Query: 13 GLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESE 72 G GP+G T G P G G D KG++G P+ Sbjct: 601 GPGPQGPPGKNGETGPQGPPGPTGPGGD-------------KGDTGPPGPQ--------- 638 Query: 73 LIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGS 132 G +G PGT GG EP P G P G G Sbjct: 639 ----------GLQGLPGT------GGPPGENGKPGEPG----PKGDAGAPGAPG----GK 674 Query: 133 TDIWADLEVG-------PSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENP------- 178 D A E G P RG P E + +AGP PGP A P Sbjct: 675 GDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGP-----PGPPGAAGTPGLQGMPG 729 Query: 179 ERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPK 238 ERG + D +P G G+ D P+ + + G + + G+P Sbjct: 730 ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTG---PIGPPGPAGQPGDKGEGGAPG 786 Query: 239 KPGDTCGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKR 298 PG G R GP P E GE P K G Sbjct: 787 LPG-IAGPRGSPGERGETGPPGP--AGFPGAPGQNGEPGGKGERGAPGEKG----EGGPP 839 Query: 299 GVRPSCSGAAVRGPL-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPAS 357 GV G+ GP P+G G + + G P RG G + PP P+ Sbjct: 840 GVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFP--GARGLPGPPGSNGNPGPPGPSG 897 Query: 358 FPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQ 416 P G G G + P P S P K AG+ P P AQ P Sbjct: 898 SPGKDGPPGPAGNTGAPGSPGVSGP-KGDAGQ--------------PGEKGSPGAQGPPG 942 Query: 417 KPELISLSVRRGEYS-SGDPNIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPPR 475 P + ++ G +G P + P+ G+ P P + SG Sbjct: 943 APGPLGIAGITGARGLAGPPGMPGPR--GSPGPQGVKGESGKPGANGLSG---------- 990 Query: 476 PERQQQPPGAQGCP 489 ++ PPG QG P Sbjct: 991 ---ERGPPGPQGLP 1001 Score = 40.8 bits (94), Expect = 0.003 Identities = 56/234 (23%), Positives = 68/234 (29%), Gaps = 31/234 (13%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP G + + G P DG+ G R G GKG+ G Sbjct: 993 GPPGPQGLPGLAGTAGEPGRDGNPGSDGLPG-RDGSPGGKGDRG---------------- 1035 Query: 75 EQGRVVLWGQEGRPGTP--VDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATA-KG 131 E G G G PG P V GD PA P+ +G P P+G KG Sbjct: 1036 ENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKG 1095 Query: 132 STDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVD 191 T G +PG ++ PGPA G Sbjct: 1096 ETGERG--AAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGT 1153 Query: 192 PQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCG 245 P GP G + + E S G PG P PG CG Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSP---------GHPGQPGPPGPPGAPGPCCG 1198 Score = 35.8 bits (81), Expect = 0.097 Identities = 108/443 (24%), Positives = 134/443 (30%), Gaps = 83/443 (18%) Query: 11 RAGLGPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKG----KG-KGESGFTDPESF 65 R G GP G E PG P G G+R G G KG KGE G + Sbjct: 695 RGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGV 754 Query: 66 SFESESELIEQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLA------DEPATIMPPSSVQ 119 + +G G G G P D GG +A E PP Sbjct: 755 PGKDG----PRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPA- 809 Query: 120 GHPSPEGATAK--GSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWEN 177 G P G + G + A E G ++ PG AGP PGP Sbjct: 810 GFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPG--GSGPAGP-------PGPQGVK 860 Query: 178 PERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSP 237 ERGS P GP G N + GS K G P Sbjct: 861 GERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPG---------------PSGSPGKDGPP 905 Query: 238 KKPGDTCGRRSFHRRESYLQVQGPL--LISPPRRLTPVVERP--AVGELDVPSLKKMQSM 293 G+T S V GP P + +P + P A G L + + + + Sbjct: 906 GPAGNTGAPGS-------PGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958 Query: 294 VWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPP 353 G G+ P PRG+ G Q K G P GA G+R PP Sbjct: 959 A-GPPGM-----------PGPRGSPG---PQGVKGESGKP-----GANGLSGER---GPP 995 Query: 354 DPASFPPVSG-VGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQ 412 P P ++G G G+ P P G+ R + P P Sbjct: 996 GPQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPV 1055 Query: 413 LPTQKPELISLSVRRGEYSSGDP 435 P K S RGE P Sbjct: 1056 GPAGK------SGDRGESGPAGP 1072 Score = 35.0 bits (79), Expect = 0.17 Identities = 94/415 (22%), Positives = 129/415 (31%), Gaps = 84/415 (20%) Query: 15 GPEGGEQAGAHTASPGAPRGDGHGRDLNFGGQRSGKGKGKGESGFTDPESFSFESESELI 74 GP G H SPG+P G + G SG G G + P Sbjct: 180 GPPGPPGTSGHPGSPGSPGYQGPPGEPGQAGP-SGPPGPPGAIGPSGPAGKD-------- 230 Query: 75 EQGRVVLWGQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPSPEGATAKGSTD 134 G+ GRPG P + G P I P+ + G P +G + Sbjct: 231 --------GESGRPGRPGERGLPG----------PPGIKGPAGIPGFPGMKGHRGFDGRN 272 Query: 135 IWADLEVGPSWRGALSPSPGEWQQASAGPLHLSVPGPGPAWENPERGSKSRLSFQVDPQQ 194 P +G + PGE + GP+ GP ERG + Sbjct: 273 GEKGETGAPGLKGE-NGLPGE--NGAPGPM-------GPRGAPGERG------------R 310 Query: 195 PSAEGPAGLNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGD-----------T 243 P G AG +D + P G+ PGSP G+ Sbjct: 311 PGLPGAAGARGNDGARGSDGQPGP------PGPPGTAGFPGSPGAKGEVGPAGSPGSNGA 364 Query: 244 CGRRSFHRRESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPS 303 G+R + + QGP PP + +G +P + G RG P Sbjct: 365 PGQRGEPGPQGHAGAQGP--PGPPGINGSPGGKGEMGPAGIPGAPGLM----GARG-PPG 417 Query: 304 CSGA----AVRG----PLPRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDP 355 +GA +RG P G G + ++ G P + GA G+ S P Sbjct: 418 PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIP--GVPGAKGEDGKDGSPGEPGA 475 Query: 356 ASFPPVSGVGLLGKSVRPKEPKHSSPGKKPAGRKTRESQAAAR-EDNDPNRDEVP 409 P +G P P K PAG + A R +P RD VP Sbjct: 476 NGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVP 530 Score = 32.3 bits (72), Expect = 1.1 Identities = 78/314 (24%), Positives = 110/314 (35%), Gaps = 63/314 (20%) Query: 83 GQEGRPGTPVDDQAGGGDYSFYLADEPATIMPPSSVQGHPS-PEGATAK-GSTDIWADLE 140 G +G PG P G P + PP + P+ P+ + + S D+ + + Sbjct: 106 GPKGDPGPPGIPGRNGDPGIPGQPGSPGSPGPPGICESCPTGPQNYSPQYDSYDVKSGVA 165 Query: 141 VGPSWRGALSPSPGEWQQASAGPLHLSVPGP-GPAWENPERGSKSRLSFQVDPQQPSAEG 199 VG L+ PG AGP PGP GP + GS +Q P +P G Sbjct: 166 VG-----GLAGYPGP-----AGP-----PGPPGPPGTSGHPGSPGSPGYQGPPGEPGQAG 210 Query: 200 PAG-------LNTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRR 252 P+G + D S P + G + PG P G G F Sbjct: 211 PSGPPGPPGAIGPSGPAGKDGESGRP-------GRPGERGLPGPPGIKG-PAGIPGFPGM 262 Query: 253 ESYLQVQGPLLISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGP 312 + + G GE P LK G+ G+ P +GA GP Sbjct: 263 KGHRGFDG--------------RNGEKGETGAPGLK-------GENGL-PGENGAP--GP 298 Query: 313 L-PRGTLGRKVAQEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGV-GLLGKS 370 + PRG G + GA GA + GQ PP A FP G G +G + Sbjct: 299 MGPRGAPGERGRPGLPGAAGA--RGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPA 356 Query: 371 VRPKEPKHSSPGKK 384 P + +PG++ Sbjct: 357 GSP--GSNGAPGQR 368 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 42.0 bits (97), Expect = 0.001 Identities = 69/339 (20%), Positives = 107/339 (31%), Gaps = 63/339 (18%) Query: 150 SPSPGEWQQASAGPLHLSVPGPGPA------WENPERGSKSRLSFQVDPQQPSAEGPAGL 203 +PSP +++ A + +P P P+ E P + S P+A Sbjct: 171 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 230 Query: 204 NTDDSDSADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLL 263 A S + + G A+ G+P+ P + LQ P Sbjct: 231 GGGLQRPASRSLSSSATPLSSPARSGPSAR-GTPRAPAHPS-----QPKPKGLQALRPPQ 284 Query: 264 ISPPRRLTPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVA 323 ++PPR+ PA+G L S + + P P GT R V Sbjct: 285 VTPPRKDAA----PALGPL----------------------SSSPLATPSPSGTKARPVP 318 Query: 324 QEKKSLEGAPELALRGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKHSSPGK 383 + P A P L PP P++ P + + P + P + Sbjct: 319 PPDNAATPLP--ATLPPSPPLATPLPLAPPSPSAPPSLQTL---------PSPPATPPSQ 367 Query: 384 KPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQ--------KPELISLSVRRGEYSSGDP 435 P T QA P+ +P Q+P P ++LS + S G P Sbjct: 368 APPSMTTPPMQAP------PSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSP 421 Query: 436 NIRAPQVLGTSQPSAFTLRRLVPRCHASSGDWQPPVHPP 474 ++A T P P AS+ PP+ P Sbjct: 422 TLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460 >gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax homolog 2 [Homo sapiens] Length = 1210 Score = 42.0 bits (97), Expect = 0.001 Identities = 74/346 (21%), Positives = 117/346 (33%), Gaps = 72/346 (20%) Query: 109 PATIMPPSSVQGHPSPEGA--TAKGSTDIWADLEVGPSWRGALSPSPGEWQQASAGPLHL 166 P++ PPS+ Q P P + ++ ++ +D + S S E + PL Sbjct: 445 PSSSAPPSAPQSLPEPVASAHSSSAESESTSDSDSSSDSESESSSSDSEENE----PLET 500 Query: 167 SVPGPGPAWEN----------------PERGSKSRLSFQVDPQQPSAEGPAGLNTDDSDS 210 P P P N P G +S +P + E ++ S Sbjct: 501 PAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRS-----TEPPRRHPESKGSSDSATSQE 555 Query: 211 ADESSDLPVIRVIISTKEGSQAKPGSPKKPGDTCGRRSFHRRESYLQVQGPLLISPPRRL 270 ES D P K S+A P+ P G+RS + P PP+R Sbjct: 556 HSESKDPP-------PKSSSKAPRAPPEAPHP--GKRSCQK--------SPAQQEPPQRQ 598 Query: 271 TPVVERPAVGELDVPSLKKMQSMVWGKRGVRPSCSGAAVRGPLPRGTLGRKVAQEKK-SL 329 T ++P K + G R S G G LP G+ + + K Sbjct: 599 TVGTKQP-----------KKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKT 647 Query: 330 EGAPELAL----RGAFPAWGQRLSAVPPDPASFPPVSGVGLLGKSVRPKEPKH------- 378 +G P A + A P ++ PA +SG +V + P+H Sbjct: 648 KGRPRAAASNEPKPAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707 Query: 379 --SSPGKKPAGRKTRESQAAAREDNDPNRDEVPRAQLPTQKPELIS 422 P +G +T + A D +D +P LP + +L+S Sbjct: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLP---LPLRDTKLLS 750 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.133 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,489,849 Number of Sequences: 37866 Number of extensions: 1745970 Number of successful extensions: 7972 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 30 Number of HSP's successfully gapped in prelim test: 404 Number of HSP's that attempted gapping in prelim test: 6937 Number of HSP's gapped (non-prelim): 1372 length of query: 518 length of database: 18,247,518 effective HSP length: 107 effective length of query: 411 effective length of database: 14,195,856 effective search space: 5834496816 effective search space used: 5834496816 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.