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Search of human proteins with 239751592
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo
sapiens]
(475 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo ... 1041 0.0
gi|169790811 SHC (Src homology 2 domain containing) transforming... 431 e-121
gi|239755199 PREDICTED: hypothetical protein [Homo sapiens] 257 1e-68
gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo ... 251 8e-67
gi|239753972 PREDICTED: hypothetical protein [Homo sapiens] 236 3e-62
gi|239755446 PREDICTED: hypothetical protein [Homo sapiens] 230 2e-60
gi|239749927 PREDICTED: hypothetical protein [Homo sapiens] 226 5e-59
gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo ... 213 2e-55
gi|239750721 PREDICTED: hypothetical protein, partial [Homo sapi... 211 9e-55
gi|224586793 src homology 2 domain-containing transforming prote... 173 3e-43
gi|194239668 SHC (Src homology 2 domain containing) transforming... 164 2e-40
gi|194239662 SHC (Src homology 2 domain containing) transforming... 164 2e-40
gi|194239664 SHC (Src homology 2 domain containing) transforming... 164 2e-40
gi|32261324 SHC (Src homology 2 domain containing) transforming ... 164 2e-40
gi|222446609 rai-like protein [Homo sapiens] 127 3e-29
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 95 1e-19
gi|169211436 PREDICTED: hypothetical protein [Homo sapiens] 78 2e-14
gi|239751395 PREDICTED: hypothetical protein, partial [Homo sapi... 78 2e-14
gi|239745904 PREDICTED: hypothetical protein, partial [Homo sapi... 78 2e-14
gi|169166365 PREDICTED: hypothetical protein [Homo sapiens] 72 1e-12
gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens] 72 1e-12
gi|169166886 PREDICTED: hypothetical protein, partial [Homo sapi... 71 2e-12
gi|124249376 proline rich 21 [Homo sapiens] 69 1e-11
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 65 2e-10
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 65 2e-10
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 65 2e-10
gi|150417989 cyclin K isoform 1 [Homo sapiens] 63 5e-10
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 63 7e-10
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 63 7e-10
gi|59938776 cAMP responsive element binding protein 5 isoform de... 62 1e-09
>gi|239751592 PREDICTED: hypothetical protein XP_002347924 [Homo
sapiens]
Length = 475
Score = 1041 bits (2693), Expect = 0.0
Identities = 475/475 (100%), Positives = 475/475 (100%)
Query: 1 MGHVELGWRRVAVMEGFPHKMPGGSSEALGTVRCHCWCPHNGTHGPHSSGFQPHNRSGLR 60
MGHVELGWRRVAVMEGFPHKMPGGSSEALGTVRCHCWCPHNGTHGPHSSGFQPHNRSGLR
Sbjct: 1 MGHVELGWRRVAVMEGFPHKMPGGSSEALGTVRCHCWCPHNGTHGPHSSGFQPHNRSGLR 60
Query: 61 VNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHP 120
VNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHP
Sbjct: 61 VNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHP 120
Query: 121 SNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHP 180
SNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHP
Sbjct: 121 SNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHP 180
Query: 181 PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTH 240
PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTH
Sbjct: 181 PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTH 240
Query: 241 PSIHPSYMGCIEVLRSMRSLDFNTRTQVTRDACSLPWDVGSTGTAPPGDGYVQADARGPP 300
PSIHPSYMGCIEVLRSMRSLDFNTRTQVTRDACSLPWDVGSTGTAPPGDGYVQADARGPP
Sbjct: 241 PSIHPSYMGCIEVLRSMRSLDFNTRTQVTRDACSLPWDVGSTGTAPPGDGYVQADARGPP 300
Query: 301 DHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPS 360
DHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPS
Sbjct: 301 DHEEHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPS 360
Query: 361 PPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAG 420
PPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAG
Sbjct: 361 PPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAG 420
Query: 421 QPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP 475
QPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP
Sbjct: 421 QPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSREP 475
>gi|169790811 SHC (Src homology 2 domain containing) transforming
protein 2 [Homo sapiens]
Length = 582
Score = 431 bits (1109), Expect = e-121
Identities = 206/206 (100%), Positives = 206/206 (100%)
Query: 270 RDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDM 329
RDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDM
Sbjct: 377 RDACSLPWDVGSTGTAPPGDGYVQADARGPPDHEEHLYVNTQGLDAPEPEDSPKKDLFDM 436
Query: 330 RPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRA 389
RPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRA
Sbjct: 437 RPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRA 496
Query: 390 AERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLID 449
AERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLID
Sbjct: 497 AERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLID 556
Query: 450 HHLQNGQPIVAAESELHLRGVVSREP 475
HHLQNGQPIVAAESELHLRGVVSREP
Sbjct: 557 HHLQNGQPIVAAESELHLRGVVSREP 582
Score = 58.2 bits (139), Expect = 2e-08
Identities = 33/59 (55%), Positives = 36/59 (61%), Gaps = 8/59 (13%)
Query: 214 IHPPIHPSIHPSTHPPTHPPVPHPSTHPSIHPSYMGCIEVLRSMRSLDFNTRTQVTRDA 272
IH P H +HP V P + YMGCIEVLRSMRSLDFNTRTQVTR+A
Sbjct: 132 IHKPAHGWLHPDAR------VLGPGVSYVVR--YMGCIEVLRSMRSLDFNTRTQVTREA 182
>gi|239755199 PREDICTED: hypothetical protein [Homo sapiens]
Length = 279
Score = 257 bits (657), Expect = 1e-68
Identities = 121/203 (59%), Positives = 135/203 (66%), Gaps = 13/203 (6%)
Query: 49 SGFQPHNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHP 108
+G P + GL + +GA I P IH IHP HP IHP +H S HPS IH HP
Sbjct: 29 AGPAPVSGEGL-LGQGAEGIGPSIHPSIHPSTHPPIHPSIHPSIHPS------IHPPVHP 81
Query: 109 SIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHP 168
SIHP PS+HPS HP VH STHPSTHPSIHP IHP ++P IHL HP IHP +HP HP
Sbjct: 82 SIHPPTRPSIHPSIHPPVHLSTHPSTHPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHP 141
Query: 169 LIHPPIHPSIHPPI-----HPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIH 223
IHPP HPSIH HPSTH THPS P +HP+ HP HP IHP IH P HPSIH
Sbjct: 142 SIHPPTHPSIHASTHPLIHHPSTHPPTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSIH 201
Query: 224 PSTHPPTHPPVPHPSTHPSIHPS 246
PSTHP TH P+ HPST+PSIHP+
Sbjct: 202 PSTHPSTH-PLTHPSTYPSIHPT 223
Score = 244 bits (624), Expect = 9e-65
Identities = 113/185 (61%), Positives = 125/185 (67%), Gaps = 14/185 (7%)
Query: 67 SIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIH--IHSSTHPSIHPFIHPSVHPSNHP 124
SIHP IH HPPIHPSIHP +H S HP +H IH S HPSIHP +H S HPS HP
Sbjct: 50 SIHPSIHPSTHPPIHPSIHPSIHPSIHPPVHPSIHPPTRPSIHPSIHPPVHLSTHPSTHP 109
Query: 125 SVHPSTHPSTHPSIH----PFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHP 180
S+HP HPS +PSIH P IHPP+HP IH IHPP HPS+H STHPLIH HPS HP
Sbjct: 110 SIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPSIHASTHPLIH---HPSTHP 166
Query: 181 PIHPSTHLSTHPSIRP----PVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPH 236
P HPSTH S HP+I P P+HPS H THP IHP HP HP HPST+P HP + H
Sbjct: 167 PTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSIHPSTHPSTHPLTHPSTYPSIHPTI-H 225
Query: 237 PSTHP 241
P T+P
Sbjct: 226 PLTYP 230
Score = 211 bits (537), Expect = 1e-54
Identities = 103/185 (55%), Positives = 109/185 (58%), Gaps = 24/185 (12%)
Query: 40 HNGTHGPHSSGFQPHNRSGLRVNKGAASIHPPIHLHIHPP----IHPSIHPPMHSSTHPS 95
H TH P P SIHPP+H IHPP IHPSIHPP+H STHPS
Sbjct: 56 HPSTHPPIHPSIHPSIHP---------SIHPPVHPSIHPPTRPSIHPSIHPPVHLSTHPS 106
Query: 96 IHLFIH----------IHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIH-PFIHP 144
H IH IH STHPSIHP IHP +HPS HP HPS H STHP IH P HP
Sbjct: 107 THPSIHPPIHPSIYPSIHLSTHPSIHPPIHPFIHPSIHPPTHPSIHASTHPLIHHPSTHP 166
Query: 145 PVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHP 204
P HP H IHP IHP HP HP IH P HPSIHP HPSTH THPS P +HP+ HP
Sbjct: 167 PTHPSTHPSIHPTIHPRAHPPIHPSIHSPTHPSIHPSTHPSTHPLTHPSTYPSIHPTIHP 226
Query: 205 STHPL 209
T+PL
Sbjct: 227 LTYPL 231
>gi|239745032 PREDICTED: hypothetical protein XP_002343336 [Homo
sapiens]
Length = 828
Score = 251 bits (642), Expect = 8e-67
Identities = 117/206 (56%), Positives = 125/206 (60%), Gaps = 24/206 (11%)
Query: 64 GAASIHPPIHLHIHPP-IHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSN 122
G IHPP+H H P IHPSIHPP H S HPSIH H THP IHP HP +HP
Sbjct: 17 GKICIHPPLHPPTHSPSIHPSIHPPTHPSIHPSIHPPTHPSIHTHPPIHPHTHPPIHPPT 76
Query: 123 HPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPI 182
HPS+HP HPS HPS+HP H +HP H H IHPS+HPSTHPLIHP IHPS H I
Sbjct: 77 HPSIHPLIHPSIHPSLHPPTHSSIHPSTHPPTHSSIHPSIHPSTHPLIHPSIHPSTHSSI 136
Query: 183 HPSTHL--STHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPS------------------- 221
HP TH STHP I P +HP TH HP IHPP HPP HPS
Sbjct: 137 HPPTHSHPSTHPLIHPSIHPPTHSPIHPSIHPPTHPPTHPSIHSSIHLPTHSSIHPPTHS 196
Query: 222 -IHPSTHPPTHPPVPHPSTHPSIHPS 246
IHPS HPPTH P+ HP THP IHPS
Sbjct: 197 FIHPSIHPPTHSPI-HPLTHPFIHPS 221
Score = 226 bits (576), Expect = 3e-59
Identities = 106/187 (56%), Positives = 114/187 (60%), Gaps = 20/187 (10%)
Query: 74 LHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPS 133
L + PP IHPP+H TH PSIHP IHP HPS HPS+HP THPS
Sbjct: 11 LAVSPPGKICIHPPLHPPTHS-------------PSIHPSIHPPTHPSIHPSIHPPTHPS 57
Query: 134 --THPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTH 191
THP IHP HPP+HPP H IHP IHPS+HPS HP H IHPS HPP H S H S H
Sbjct: 58 IHTHPPIHPHTHPPIHPPTHPSIHPLIHPSIHPSLHPPTHSSIHPSTHPPTHSSIHPSIH 117
Query: 192 PSIRPPVHPSTHPSTHPLIHPPIH--PPIHPSIHPSTHPPTHPPVP---HPSTHPSIHPS 246
PS P +HPS HPSTH IHPP H P HP IHPS HPPTH P+ HP THP HPS
Sbjct: 118 PSTHPLIHPSIHPSTHSSIHPPTHSHPSTHPLIHPSIHPPTHSPIHPSIHPPTHPPTHPS 177
Query: 247 YMGCIEV 253
I +
Sbjct: 178 IHSSIHL 184
Score = 174 bits (442), Expect = 1e-43
Identities = 82/185 (44%), Positives = 97/185 (52%), Gaps = 18/185 (9%)
Query: 40 HNGTHGPHSSGFQPHNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99
H H P S P S HPP H IHP IHPS HP +H S HPS H
Sbjct: 89 HPSLHPPTHSSIHP-------------STHPPTHSSIHPSIHPSTHPLIHPSIHPSTHSS 135
Query: 100 IHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIH 159
IH + +HPS HP IHPS+HP H +HPS HP THP HP IH +H P H IHPP H
Sbjct: 136 IHPPTHSHPSTHPLIHPSIHPPTHSPIHPSIHPPTHPPTHPSIHSSIHLPTHSSIHPPTH 195
Query: 160 PSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTH-----PSIRPPVHPSTHPSTHPLIHPPI 214
+HPS HP H PIHP HP IHPS + P+++ + P+ P++
Sbjct: 196 SFIHPSIHPPTHSPIHPLTHPFIHPSDSSAASAGGVGPALQTRMSGHPRPTGSPVLALAS 255
Query: 215 HPPIH 219
HPP H
Sbjct: 256 HPPWH 260
>gi|239753972 PREDICTED: hypothetical protein [Homo sapiens]
Length = 298
Score = 236 bits (602), Expect = 3e-62
Identities = 115/229 (50%), Positives = 137/229 (59%), Gaps = 31/229 (13%)
Query: 66 ASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIH--IHSSTHPSIHPFIHPSVHPSNH 123
+S HPPIH H PIHPS H P+H STHP IH + IH ST+P IHP HP++HPS H
Sbjct: 55 SSTHPPIHPSTHLPIHPSTHLPIHPSTHPPIHPSTNPPIHPSTNPPIHPSTHPTIHPSTH 114
Query: 124 PS-----VHPSTHPSTHPSIHP----FIHPP-------------VHPPIHLHIHPPIHPS 161
P +HPS HP HP IHP FIHPP +H P HL I+PP +PS
Sbjct: 115 PPSTYLPIHPSAHPLIHPFIHPLTHLFIHPPPTHSPIHPPTHSSIHLPTHLSIYPPTYPS 174
Query: 162 VHP--STHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIH 219
+HP + HP IHPPIHPS HP IHPSTH STHP PP HP ++PS H IHPPIHPP H
Sbjct: 175 IHPPPTPHPSIHPPIHPSTHPLIHPSTHTSTHPPTHPPTHPPSNPSIHSSIHPPIHPPTH 234
Query: 220 PSIHPSTHPPTHPPVPHPSTHPSIHPSYMGCIEVLRSMRSLDFNTRTQV 268
PS HP H T HPST+ S HP + + ++ R ++R +
Sbjct: 235 PSTHPPIHSST-----HPSTYFSTHPPLLSPKVLQKAFRPFSLSSRIPI 278
Score = 226 bits (575), Expect = 5e-59
Identities = 112/202 (55%), Positives = 126/202 (62%), Gaps = 32/202 (15%)
Query: 76 IHPPIHPSI-----HPPMHSST----HPSIHLFIH------IHSSTHPSIHPFIHPSVHP 120
++ P HP+I HPP+H ST HPS HL IH IH ST+P IHP +P +HP
Sbjct: 44 LNQPTHPTIHPSSTHPPIHPSTHLPIHPSTHLPIHPSTHPPIHPSTNPPIHPSTNPPIHP 103
Query: 121 SNHPSVHPST---------HPSTHPSIHPFIHPPVH-----PPIHLHIHPPIHPSVHPST 166
S HP++HPST HPS HP IHPFIHP H PP H IHPP H S+H T
Sbjct: 104 STHPTIHPSTHPPSTYLPIHPSAHPLIHPFIHPLTHLFIHPPPTHSPIHPPTHSSIHLPT 163
Query: 167 HPLIHPPIHPSIHPP--IHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHP 224
H I+PP +PSIHPP HPS H HPS P +HPSTH STHP HPP HPP +PSIH
Sbjct: 164 HLSIYPPTYPSIHPPPTPHPSIHPPIHPSTHPLIHPSTHTSTHPPTHPPTHPPSNPSIHS 223
Query: 225 STHPPTHPPVPHPSTHPSIHPS 246
S HPP HPP HPSTHP IH S
Sbjct: 224 SIHPPIHPPT-HPSTHPPIHSS 244
Score = 53.9 bits (128), Expect = 3e-07
Identities = 27/47 (57%), Positives = 31/47 (65%), Gaps = 10/47 (21%)
Query: 209 LIHPPIHPPIHPS-----IHPSTHPPTHP----PVPHPSTHPSIHPS 246
+++ P HP IHPS IHPSTH P HP P+ HPSTHP IHPS
Sbjct: 43 VLNQPTHPTIHPSSTHPPIHPSTHLPIHPSTHLPI-HPSTHPPIHPS 88
>gi|239755446 PREDICTED: hypothetical protein [Homo sapiens]
Length = 394
Score = 230 bits (586), Expect = 2e-60
Identities = 114/215 (53%), Positives = 131/215 (60%), Gaps = 20/215 (9%)
Query: 77 HPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHP 136
HP IHPSI+ +H S HPSIH FIH P+IH HPS+HPS HPS+HP THPS HP
Sbjct: 113 HPSIHPSINSFIHPSMHPSIHPFIH-----PPTIHSSTHPSIHPSIHPSIHPPTHPSIHP 167
Query: 137 SIHPFIHPPVHPPIHLH-----IHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTH 191
SIHPFIHP +HP IHL IHP I+P ++ S HP IHP H SI+PPIHPS HLSTH
Sbjct: 168 SIHPFIHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHPSFHASIYPPIHPSIHLSTH 227
Query: 192 PSIRPPVHPSTHP-------STHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTHPSIH 244
SI PP+HPS H S HP +H IH IH SIHPSTHP HP + HPS H SIH
Sbjct: 228 LSIHPPIHPSVHSPIHLSTHSIHPSVHSSIHSSIHSSIHPSTHPSIHPLI-HPSIHLSIH 286
Query: 245 PS--YMGCIEVLRSMRSLDFNTRTQVTRDACSLPW 277
P Y + + R F R + + W
Sbjct: 287 PENFYEAALSTKSTSRMCIFGARGLLLSEGTRESW 321
Score = 202 bits (513), Expect = 7e-52
Identities = 101/190 (53%), Positives = 114/190 (60%), Gaps = 16/190 (8%)
Query: 40 HNGTHGPHSSGFQPHNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99
H H +S P + +IH H IHP IHPSIHPP THPSIH
Sbjct: 113 HPSIHPSINSFIHPSMHPSIHPFIHPPTIHSSTHPSIHPSIHPSIHPP----THPSIH-- 166
Query: 100 IHIHSSTHPSIHPFIHPSVHPSNHPSVHPS-THPSTHPSIHPFIHPPVHPPIHLHIHPPI 158
PSIHPFIHPS+HPS H S+H S HP +P I+ IHP +HP H I+PPI
Sbjct: 167 --------PSIHPFIHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHPSFHASIYPPI 218
Query: 159 HPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPI 218
HPS+H STH IHPPIHPS+H PIH STH S HPS+ +H S H S HP HP IHP I
Sbjct: 219 HPSIHLSTHLSIHPPIHPSVHSPIHLSTH-SIHPSVHSSIHSSIHSSIHPSTHPSIHPLI 277
Query: 219 HPSIHPSTHP 228
HPSIH S HP
Sbjct: 278 HPSIHLSIHP 287
Score = 158 bits (399), Expect = 1e-38
Identities = 82/164 (50%), Positives = 88/164 (53%), Gaps = 48/164 (29%)
Query: 130 THPSTHPSIHPFIHPPVHPPIHLHIHPP-------------IHPSVHPSTHPLIHPPIHP 176
+HPS HPSI+ FIHP +HP IH IHPP IHPS+HP THP IHP IHP
Sbjct: 112 SHPSIHPSINSFIHPSMHPSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIHP 171
Query: 177 SIHPPIHPSTHLSTHPSIRPP---------VHPSTHPSTHPLIHPPIHPPIHPSIHPSTH 227
IHP IHPS HLS H SI P +HPS HPS H I+PPIHP IH S H S H
Sbjct: 172 FIHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHPSFHASIYPPIHPSIHLSTHLSIH 231
Query: 228 PPTHPPVP--------------------------HPSTHPSIHP 245
PP HP V HPSTHPSIHP
Sbjct: 232 PPIHPSVHSPIHLSTHSIHPSVHSSIHSSIHSSIHPSTHPSIHP 275
Score = 85.9 bits (211), Expect = 7e-17
Identities = 40/62 (64%), Positives = 42/62 (67%), Gaps = 6/62 (9%)
Query: 186 THLSTHPSIRPPVHPSTHPSTHPLIHPP-IHPPIHPSIHPSTHPPTHPPVPHPSTHPSIH 244
+H S HPSI +HPS HPS HP IHPP IH HPSIHPS HP HPP THPSIH
Sbjct: 112 SHPSIHPSINSFIHPSMHPSIHPFIHPPTIHSSTHPSIHPSIHPSIHPP-----THPSIH 166
Query: 245 PS 246
PS
Sbjct: 167 PS 168
>gi|239749927 PREDICTED: hypothetical protein [Homo sapiens]
Length = 295
Score = 226 bits (575), Expect = 5e-59
Identities = 105/176 (59%), Positives = 115/176 (65%), Gaps = 24/176 (13%)
Query: 77 HPPIHPSIHPPMHSSTHPSIHLFIH---IHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPS 133
HP IHPSI+ +H S HPSIH FIH IHSSTHPSIHP IHPS+HP HPS+HPS HP
Sbjct: 13 HPSIHPSINSFIHPSMHPSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIHPF 72
Query: 134 THPSIHPFIH---------------------PPVHPPIHLHIHPPIHPSVHPSTHPLIHP 172
HPSIHP IH P +HP H I+PPIHPS+H STH IHP
Sbjct: 73 IHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHPSFHASIYPPIHPSIHLSTHLSIHP 132
Query: 173 PIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP 228
PIHPS+H PIH STHLS HPS+ +H S H S HP HP IHP IHPSIH S HP
Sbjct: 133 PIHPSVHSPIHLSTHLSIHPSVHSSIHSSIHSSIHPSTHPSIHPLIHPSIHLSIHP 188
Score = 161 bits (407), Expect = 1e-39
Identities = 81/142 (57%), Positives = 87/142 (61%), Gaps = 25/142 (17%)
Query: 130 THPSTHPSIHPFIHPPVHPPIHLHIHPP-------------IHPSVHPSTHPLIHPPIHP 176
+HPS HPSI+ FIHP +HP IH IHPP IHPS+HP THP IHP IHP
Sbjct: 12 SHPSIHPSINSFIHPSMHPSIHPFIHPPTIHSSTHPSIHPSIHPSIHPPTHPSIHPSIHP 71
Query: 177 SIHPPIHPSTHLSTHPSIRPP---------VHPSTHPSTHPLIHPPIHPPIHPSIHPSTH 227
IHP IHPS HLS H SI P +HPS HPS H I+PPIHP IH S H S H
Sbjct: 72 FIHPSIHPSIHLSIHQSIIHPLIYPLIYLSIHPSIHPSFHASIYPPIHPSIHLSTHLSIH 131
Query: 228 PPTHPPVPHP---STHPSIHPS 246
PP HP V P STH SIHPS
Sbjct: 132 PPIHPSVHSPIHLSTHLSIHPS 153
>gi|239746716 PREDICTED: hypothetical protein XP_002343819 [Homo
sapiens]
Length = 217
Score = 213 bits (543), Expect = 2e-55
Identities = 100/175 (57%), Positives = 114/175 (65%), Gaps = 17/175 (9%)
Query: 93 HPSIHLFIH--IHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPI 150
HPSI++FIH H HPSIHP IHP +HP + S+HP T+ S HPS+HP IHP +HP
Sbjct: 2 HPSIYIFIHPSTHIFIHPSIHPSIHPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIHPST 61
Query: 151 HLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLI 210
H HIHP IHPS+ PS HP IHP I PS + IHPSTH+S HPSI P +H HPSTH I
Sbjct: 62 HPHIHPSIHPSI-PSIHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFI 120
Query: 211 HPPI--------HPPIHPS-----IHPSTHPPTHPPVPHPSTHPSIHPSYMGCIE 252
HP I HP IHPS IHPS HP THPP+ HP HPSIHP +E
Sbjct: 121 HPSIHSSIHASTHPHIHPSIYPLFIHPSIHPSTHPPI-HPQIHPSIHPLLTNLVE 174
Score = 211 bits (536), Expect = 2e-54
Identities = 97/162 (59%), Positives = 109/162 (67%), Gaps = 4/162 (2%)
Query: 68 IHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVH 127
IHP H+ IHP IHPSIHP +H T+ SIH +SS HPS+HP IHPS+HPS HP +H
Sbjct: 9 IHPSTHIFIHPSIHPSIHPCIHPPTYSSIH--PPTYSSIHPSVHPHIHPSIHPSTHPHIH 66
Query: 128 PSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTH 187
PS HPS PSIHP IHP + P + IHP H S+HPS HP IH IHPS H IHPS H
Sbjct: 67 PSIHPSI-PSIHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFIHPSIH 125
Query: 188 LSTHPSIRPPVHPSTHP-STHPLIHPPIHPPIHPSIHPSTHP 228
S H S P +HPS +P HP IHP HPPIHP IHPS HP
Sbjct: 126 SSIHASTHPHIHPSIYPLFIHPSIHPSTHPPIHPQIHPSIHP 167
Score = 199 bits (507), Expect = 3e-51
Identities = 95/155 (61%), Positives = 104/155 (67%), Gaps = 8/155 (5%)
Query: 67 SIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSV 126
SIHP IH IHPP + SIHPP +SS HPS+H HIH S HPS HP IHPS+HPS
Sbjct: 20 SIHPSIHPCIHPPTYSSIHPPTYSSIHPSVH--PHIHPSIHPSTHPHIHPSIHPS----- 72
Query: 127 HPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPST 186
PS HPS HPSI P + +HP H+ IHP IHPS+H HP H IHPSIH IH ST
Sbjct: 73 IPSIHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFIHPSIHSSIHAST 132
Query: 187 HLSTHPSIRPP-VHPSTHPSTHPLIHPPIHPPIHP 220
H HPSI P +HPS HPSTHP IHP IHP IHP
Sbjct: 133 HPHIHPSIYPLFIHPSIHPSTHPPIHPQIHPSIHP 167
Score = 173 bits (438), Expect = 4e-43
Identities = 82/139 (58%), Positives = 91/139 (65%), Gaps = 10/139 (7%)
Query: 118 VHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPS 177
+HPS + +HPSTH HPSIHP IHP +HPP + IHPP + S+HPS HP IHP IHPS
Sbjct: 1 MHPSIYIFIHPSTHIFIHPSIHPSIHPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIHPS 60
Query: 178 IHPPIH-------PSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPT 230
HP IH PS H S HPSIRP + S HPSTH IHP IHP IH IHPSTH
Sbjct: 61 THPHIHPSIHPSIPSIHPSIHPSIRPSTYSSIHPSTHISIHPSIHPSIHLHIHPSTHIFI 120
Query: 231 HPPVP---HPSTHPSIHPS 246
HP + H STHP IHPS
Sbjct: 121 HPSIHSSIHASTHPHIHPS 139
Score = 127 bits (319), Expect = 2e-29
Identities = 71/154 (46%), Positives = 80/154 (51%), Gaps = 33/154 (21%)
Query: 40 HNGTHGPHSSGFQPHNRSGLRVNKGA---ASIHPPIHLHIHPPIHPSI------------ 84
H H P S P S + + SIHP H HIHP IHPSI
Sbjct: 26 HPCIHPPTYSSIHPPTYSSIHPSVHPHIHPSIHPSTHPHIHPSIHPSIPSIHPSIHPSIR 85
Query: 85 -------HPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
HP H S HPSIH IH+H HPS H FIHPS+ H S+H STHP HPS
Sbjct: 86 PSTYSSIHPSTHISIHPSIHPSIHLH--IHPSTHIFIHPSI----HSSIHASTHPHIHPS 139
Query: 138 IHP-FIHPPVHPPIHLHIHPPIHPSVHPSTHPLI 170
I+P FIHP +HP HPPIHP +HPS HPL+
Sbjct: 140 IYPLFIHPSIHP----STHPPIHPQIHPSIHPLL 169
>gi|239750721 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 230
Score = 211 bits (538), Expect = 9e-55
Identities = 114/225 (50%), Positives = 129/225 (57%), Gaps = 44/225 (19%)
Query: 67 SIHPPIHLHIHPPI----HPSIHPPMHSSTHPSIHLFIH--IHSSTHPSIHP----FIHP 116
SIHP IHL IHP I HP IHPP+ SS HPSIH IH IH S HP IHP IHP
Sbjct: 2 SIHPSIHLSIHPSIYPFIHPCIHPPICSSIHPSIHPSIHPSIHLSIHPCIHPPICSSIHP 61
Query: 117 SVHPSNHPSVHPSTHPSTHPSIH--PFIHPPVHPPIH------------------LHIHP 156
S+HPS + +H S HPS H SIH P IHP +HP IH +HIHP
Sbjct: 62 SIHPSTYLFIHLSMHPSIHASIHLHPSIHPSIHPSIHTYMHTSTYLFIHLSMHPSIHIHP 121
Query: 157 PIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP----VHPSTHPSTHPLIHP 212
I PS+HPS H IH IH S+HP H S H HPS+ P +HPS HPS H IHP
Sbjct: 122 SICPSIHPSIHSSIHASIHLSVHPSFHASIHPCIHPSMHPSTYLFIHPSMHPSIHASIHP 181
Query: 213 P---------IHPPIHPSIHPSTHPPTHPPVPHPSTHPSIHPSYM 248
P IHP ++PSIH S H HP + HPS HPSIH S++
Sbjct: 182 PICSSIFPLFIHPSLYPSIHASIHLSVHPSI-HPSIHPSIHLSFL 225
Score = 174 bits (442), Expect = 1e-43
Identities = 92/176 (52%), Positives = 107/176 (60%), Gaps = 10/176 (5%)
Query: 40 HNGTHGPHSSGFQP--HNRSGLRVNKGA-ASIHPPIHLH--IHPPIHPSIHPPMHSSTHP 94
H H P S P H + L ++ SIH IHLH IHP IHPSIH MH+ST+
Sbjct: 48 HPCIHPPICSSIHPSIHPSTYLFIHLSMHPSIHASIHLHPSIHPSIHPSIHTYMHTSTYL 107
Query: 95 SIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHI 154
IHL +H HPSI P IHPS+H S H S+H S HPS H SIHP IHP +HP +L I
Sbjct: 108 FIHLSMHPSIHIHPSICPSIHPSIHSSIHASIHLSVHPSFHASIHPCIHPSMHPSTYLFI 167
Query: 155 HPPIHPSVHPSTHPLIHPP-----IHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPS 205
HP +HPS+H S HP I IHPS++P IH S HLS HPSI P +HPS H S
Sbjct: 168 HPSMHPSIHASIHPPICSSIFPLFIHPSLYPSIHASIHLSVHPSIHPSIHPSIHLS 223
Score = 119 bits (297), Expect = 8e-27
Identities = 67/133 (50%), Positives = 74/133 (55%), Gaps = 25/133 (18%)
Query: 152 LHIHPPIHPSVHPS----THPLIHPP----IHPSIHPPIHPSTHLSTHPSIRPP----VH 199
L IHP IH S+HPS HP IHPP IHPSIHP IHPS HLS HP I PP +H
Sbjct: 1 LSIHPSIHLSIHPSIYPFIHPCIHPPICSSIHPSIHPSIHPSIHLSIHPCIHPPICSSIH 60
Query: 200 PSTHPSTHPLIHPPIHPPIHPSI--HPSTHPPTHPPVP-----------HPSTHPSIHPS 246
PS HPST+ IH +HP IH SI HPS HP HP + H S HPSIH
Sbjct: 61 PSIHPSTYLFIHLSMHPSIHASIHLHPSIHPSIHPSIHTYMHTSTYLFIHLSMHPSIHIH 120
Query: 247 YMGCIEVLRSMRS 259
C + S+ S
Sbjct: 121 PSICPSIHPSIHS 133
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/53 (47%), Positives = 31/53 (58%), Gaps = 9/53 (16%)
Query: 66 ASIHPPI---------HLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPS 109
ASIHPPI H ++P IH SIH +H S HPSIH IH+ ++PS
Sbjct: 177 ASIHPPICSSIFPLFIHPSLYPSIHASIHLSVHPSIHPSIHPSIHLSFLSYPS 229
Score = 45.8 bits (107), Expect = 8e-05
Identities = 20/39 (51%), Positives = 25/39 (64%)
Query: 68 IHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSST 106
IHP ++ IH IH S+HP +H S HPSIHL + ST
Sbjct: 192 IHPSLYPSIHASIHLSVHPSIHPSIHPSIHLSFLSYPST 230
>gi|224586793 src homology 2 domain-containing transforming protein
C3 [Homo sapiens]
Length = 594
Score = 173 bits (439), Expect = 3e-43
Identities = 96/182 (52%), Positives = 116/182 (63%), Gaps = 12/182 (6%)
Query: 300 PDHEEHLYVNTQGLD-------APEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPL 352
P E YVNTQ + E SP+KDLFDM+PFEDALK A+
Sbjct: 417 PTGEAPTYVNTQQIPPQAWPAAVSSAESSPRKDLFDMKPFEDALKNQPLGPVLSKAASV- 475
Query: 353 PLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQY 412
+ SP + RAP A E+L+ E WY G MSR+ AE +L DGDFLVR S TNPG +
Sbjct: 476 ----ECISPVSPRAPDAKMLEELQAETWYQGEMSRKEAEGLLEKDGDFLVRKSTTNPGSF 531
Query: 413 VLTGMHAGQPKHLLLVDPEGVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVS 472
VLTGMH GQ KHLLLVDPEG +RTKD +F+SISHLI+HHL++ PIV+A SEL L+ V
Sbjct: 532 VLTGMHNGQAKHLLLVDPEGTIRTKDRVFDSISHLINHHLESSLPIVSAGSELCLQQPVE 591
Query: 473 RE 474
R+
Sbjct: 592 RK 593
Score = 54.3 bits (129), Expect = 2e-07
Identities = 31/58 (53%), Positives = 36/58 (62%), Gaps = 7/58 (12%)
Query: 224 PSTHPPTHPP--VPHPSTH---PSIH--PSYMGCIEVLRSMRSLDFNTRTQVTRDACS 274
P P PP PH S P + Y+GCIEVLRSMRSLDF+TRTQ+TR+A S
Sbjct: 129 PGDEPLPRPPRGAPHASDQVLGPGVTYVVKYLGCIEVLRSMRSLDFSTRTQITREAIS 186
>gi|194239668 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 4 [Homo sapiens]
Length = 473
Score = 164 bits (415), Expect = 2e-40
Identities = 99/220 (45%), Positives = 126/220 (57%), Gaps = 45/220 (20%)
Query: 276 PWDVGST---GTAPPGDGYVQADARGPPD------HEEHLYVNTQGLDA----------- 315
P +G+T G GD V+ PP ++ YVN Q LD
Sbjct: 277 PSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPP 336
Query: 316 -PEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQ 374
P S +DLFDM+PFEDAL++ PP + +A EQ
Sbjct: 337 NPAINGSAPRDLFDMKPFEDALRV---------------------PPPPQSVSMA---EQ 372
Query: 375 LRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV 434
LR EPW+HG++SRR AE +L+ +GDFLVR+S T PGQYVLTG+ +GQPKHLLLVDPEGVV
Sbjct: 373 LRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVV 432
Query: 435 RTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSRE 474
RTKD FES+SHLI +H+ N PI++A SEL L+ V R+
Sbjct: 433 RTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 472
Score = 53.9 bits (128), Expect = 3e-07
Identities = 24/29 (82%), Positives = 28/29 (96%)
Query: 247 YMGCIEVLRSMRSLDFNTRTQVTRDACSL 275
YMGC+EVL+SMR+LDFNTRTQVTR+A SL
Sbjct: 56 YMGCVEVLQSMRALDFNTRTQVTREAISL 84
>gi|194239662 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 1 [Homo sapiens]
Length = 583
Score = 164 bits (415), Expect = 2e-40
Identities = 99/220 (45%), Positives = 126/220 (57%), Gaps = 45/220 (20%)
Query: 276 PWDVGST---GTAPPGDGYVQADARGPPD------HEEHLYVNTQGLDA----------- 315
P +G+T G GD V+ PP ++ YVN Q LD
Sbjct: 387 PSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRELFDDPSYVNVQNLDKARQAVGGAGPP 446
Query: 316 -PEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQ 374
P S +DLFDM+PFEDAL++ PP + +A EQ
Sbjct: 447 NPAINGSAPRDLFDMKPFEDALRV---------------------PPPPQSVSMA---EQ 482
Query: 375 LRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGVV 434
LR EPW+HG++SRR AE +L+ +GDFLVR+S T PGQYVLTG+ +GQPKHLLLVDPEGVV
Sbjct: 483 LRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGVV 542
Query: 435 RTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSRE 474
RTKD FES+SHLI +H+ N PI++A SEL L+ V R+
Sbjct: 543 RTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 582
Score = 53.9 bits (128), Expect = 3e-07
Identities = 24/29 (82%), Positives = 28/29 (96%)
Query: 247 YMGCIEVLRSMRSLDFNTRTQVTRDACSL 275
YMGC+EVL+SMR+LDFNTRTQVTR+A SL
Sbjct: 166 YMGCVEVLQSMRALDFNTRTQVTREAISL 194
>gi|194239664 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 3 [Homo sapiens]
Length = 584
Score = 164 bits (414), Expect = 2e-40
Identities = 99/221 (44%), Positives = 126/221 (57%), Gaps = 46/221 (20%)
Query: 276 PWDVGST---GTAPPGDGYVQADARGPPD-------HEEHLYVNTQGLDA---------- 315
P +G+T G GD V+ PP ++ YVN Q LD
Sbjct: 387 PSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGP 446
Query: 316 --PEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEE 373
P S +DLFDM+PFEDAL++ PP + +A E
Sbjct: 447 PNPAINGSAPRDLFDMKPFEDALRV---------------------PPPPQSVSMA---E 482
Query: 374 QLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGV 433
QLR EPW+HG++SRR AE +L+ +GDFLVR+S T PGQYVLTG+ +GQPKHLLLVDPEGV
Sbjct: 483 QLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGV 542
Query: 434 VRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSRE 474
VRTKD FES+SHLI +H+ N PI++A SEL L+ V R+
Sbjct: 543 VRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 583
Score = 53.9 bits (128), Expect = 3e-07
Identities = 24/29 (82%), Positives = 28/29 (96%)
Query: 247 YMGCIEVLRSMRSLDFNTRTQVTRDACSL 275
YMGC+EVL+SMR+LDFNTRTQVTR+A SL
Sbjct: 166 YMGCVEVLQSMRALDFNTRTQVTREAISL 194
>gi|32261324 SHC (Src homology 2 domain containing) transforming
protein 1 isoform 2 [Homo sapiens]
Length = 474
Score = 164 bits (414), Expect = 2e-40
Identities = 99/221 (44%), Positives = 126/221 (57%), Gaps = 46/221 (20%)
Query: 276 PWDVGST---GTAPPGDGYVQADARGPPD-------HEEHLYVNTQGLDA---------- 315
P +G+T G GD V+ PP ++ YVN Q LD
Sbjct: 277 PSHLGATLPVGQPVGGDPEVRKQMPPPPPCPAGRELFDDPSYVNVQNLDKARQAVGGAGP 336
Query: 316 --PEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEE 373
P S +DLFDM+PFEDAL++ PP + +A E
Sbjct: 337 PNPAINGSAPRDLFDMKPFEDALRV---------------------PPPPQSVSMA---E 372
Query: 374 QLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPEGV 433
QLR EPW+HG++SRR AE +L+ +GDFLVR+S T PGQYVLTG+ +GQPKHLLLVDPEGV
Sbjct: 373 QLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEGV 432
Query: 434 VRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSRE 474
VRTKD FES+SHLI +H+ N PI++A SEL L+ V R+
Sbjct: 433 VRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 473
Score = 53.9 bits (128), Expect = 3e-07
Identities = 24/29 (82%), Positives = 28/29 (96%)
Query: 247 YMGCIEVLRSMRSLDFNTRTQVTRDACSL 275
YMGC+EVL+SMR+LDFNTRTQVTR+A SL
Sbjct: 56 YMGCVEVLQSMRALDFNTRTQVTREAISL 84
>gi|222446609 rai-like protein [Homo sapiens]
Length = 630
Score = 127 bits (318), Expect = 3e-29
Identities = 68/163 (41%), Positives = 97/163 (59%), Gaps = 13/163 (7%)
Query: 325 DLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQW-------------PSPPTRRAPVAPT 371
DLFD + + L +AG + PL W + P +
Sbjct: 458 DLFDDPCYINTQALQSTPGSAGNQRSAQPLGSPWHCGKAPETVQPGATAQPASSHSLPHI 517
Query: 372 EEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLLVDPE 431
++QL E YHG++SR+AAE +L DGDFLVR+S T+PGQYVL+G+ GQ KHLLLVDPE
Sbjct: 518 KQQLWSEECYHGKLSRKAAESLLVKDGDFLVRESATSPGQYVLSGLQGGQAKHLLLVDPE 577
Query: 432 GVVRTKDVLFESISHLIDHHLQNGQPIVAAESELHLRGVVSRE 474
G VRTKD +F+++ HLI +H+ N PI+++ SE+ L+ V ++
Sbjct: 578 GKVRTKDHVFDNVGHLIRYHMDNSLPIISSGSEVSLKQPVRKD 620
Score = 48.9 bits (115), Expect = 1e-05
Identities = 22/28 (78%), Positives = 25/28 (89%)
Query: 247 YMGCIEVLRSMRSLDFNTRTQVTRDACS 274
YMGC+EVL+SMRSLDF RTQVTR+A S
Sbjct: 196 YMGCVEVLQSMRSLDFGMRTQVTREAIS 223
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 95.1 bits (235), Expect = 1e-19
Identities = 74/191 (38%), Positives = 87/191 (45%), Gaps = 32/191 (16%)
Query: 61 VNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHP 120
V+ A+ +HPP +HPP P +HPP HP S HP P VHP
Sbjct: 294 VHPPASGVHPPAP-GVHPPA-PGVHPPA-PGVHPPT-------SGVHPPA-----PGVHP 338
Query: 121 SNHPSVHPSTHPSTHPSIHPFIHPP---VHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPS 177
P VHP P HP P +HPP VHPP +HP P VHP+ P +HP P
Sbjct: 339 PA-PGVHPPA-PGVHPPA-PGVHPPAPGVHPPPSAGVHPQA-PGVHPAA-PAVHPQA-PG 392
Query: 178 IHPP---IHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPV 234
+HPP +HP HP P VHPS P HP PP P +P +HP T P
Sbjct: 393 VHPPAPGMHPQAP-GVHPQ-PPGVHPSA-PGVHP--QPPGVHPSNPGVHPPTPMPPMLRP 447
Query: 235 PHPSTHPSIHP 245
P PS P P
Sbjct: 448 PLPSEGPGNIP 458
Score = 94.4 bits (233), Expect = 2e-19
Identities = 77/205 (37%), Positives = 92/205 (44%), Gaps = 58/205 (28%)
Query: 64 GAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHP---SVHP 120
G A PP + PP P +HPP P +HP VHP
Sbjct: 268 GPAPSGPPGPPQLPPPA-PGVHPPA-----------------------PVVHPPASGVHP 303
Query: 121 SNHPSVHPSTHPSTHPSIHPFIHPP---VHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPS 177
P VHP P HP P +HPP VHPP +HPP P VHP P +HPP P
Sbjct: 304 P-APGVHPPA-PGVHPPA-PGVHPPTSGVHPPAP-GVHPPA-PGVHPPA-PGVHPPA-PG 356
Query: 178 IHPP---IHPSTHLSTHPSIRPPVHPSTHPSTHPL---IHPP---IHP------PIHPSI 222
+HPP +HP HP P VHP+ P+ HP +HPP +HP P P +
Sbjct: 357 VHPPAPGVHPPPSAGVHPQ-APGVHPAA-PAVHPQAPGVHPPAPGMHPQAPGVHPQPPGV 414
Query: 223 HPSTHPPTHPPVP--HPSTHPSIHP 245
HPS P HP P HPS +P +HP
Sbjct: 415 HPSA-PGVHPQPPGVHPS-NPGVHP 437
Score = 62.0 bits (149), Expect = 1e-09
Identities = 47/137 (34%), Positives = 58/137 (42%), Gaps = 26/137 (18%)
Query: 136 PSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPP---IHPSTHLSTH- 191
P + + PP + L PP P+ P PP P +HPP +HP H
Sbjct: 245 PPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPPAS-GVHP 303
Query: 192 --PSIRPP---VHPSTHPSTHPL---IHPP---IHPPIHPSIH---PSTHPP---THPPV 234
P + PP VHP P HP +HPP +HPP P +H P HPP HPP
Sbjct: 304 PAPGVHPPAPGVHPPA-PGVHPPTSGVHPPAPGVHPPA-PGVHPPAPGVHPPAPGVHPPA 361
Query: 235 P--HPSTHPSIHPSYMG 249
P HP +HP G
Sbjct: 362 PGVHPPPSAGVHPQAPG 378
Score = 52.4 bits (124), Expect = 9e-07
Identities = 43/134 (32%), Positives = 54/134 (40%), Gaps = 37/134 (27%)
Query: 145 PVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSI------------HPPIHPSTHLSTHP 192
P PP PP+ + P PP+ S+ PP P+ P
Sbjct: 224 PAGPPGVKRPPPPLMNGLPP------RPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGP 277
Query: 193 SIRPPVHPSTHPSTHPLIHPP---IHPP---IH---PSIH---PSTHPPT---HPPVP-- 235
PP P HP P++HPP +HPP +H P +H P HPPT HPP P
Sbjct: 278 PQLPPPAPGVHPPA-PVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPPAPGV 336
Query: 236 HPSTHPSIHPSYMG 249
HP P +HP G
Sbjct: 337 HPPA-PGVHPPAPG 349
>gi|169211436 PREDICTED: hypothetical protein [Homo sapiens]
Length = 280
Score = 78.2 bits (191), Expect = 2e-14
Identities = 51/172 (29%), Positives = 83/172 (48%), Gaps = 9/172 (5%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + P P + S P++ S+ P++ P P++ PS+ P++ PS+ P+ PS
Sbjct: 76 PTLTPCSTPTLTPSNTPTLT------PSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 129
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P + PS P+ P P + PS P + PS+ + PS RP
Sbjct: 130 STPTLTPSSTPTLTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI 189
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP---PTHPPVPHPSTHPSIHPS 246
+ S+ P+ P P + P P++ PS P P+ P PS+ P++ PS
Sbjct: 190 LTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPS 241
Score = 72.4 bits (176), Expect = 8e-13
Identities = 49/172 (28%), Positives = 82/172 (47%), Gaps = 9/172 (5%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ S+ P++ P P++ PS+ P++ S+ P+ PS
Sbjct: 100 PTLTPSSTPTLTPSSTPTLT------PSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPS 153
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P + PS P+ P P + S P + PS+ + PS P
Sbjct: 154 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPT 213
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPP---THPPVPHPSTHPSIHPS 246
+ PS P+ P P + P P++ PS+ P + P PS+ P++ PS
Sbjct: 214 LTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPTLTRSSTPTLTPSSTPTLTPS 265
Score = 72.0 bits (175), Expect = 1e-12
Identities = 47/155 (30%), Positives = 76/155 (49%), Gaps = 6/155 (3%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ SST P++ P P++ PS+ P++ PS+ P+ PS
Sbjct: 124 PTLTPSSTPTLTPSSTPTL-----TRSST-PTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 177
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P + PS P+ P P + PS P + PS+ + PS P
Sbjct: 178 STPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPT 237
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHP 232
+ PS+ P+ P + P P++ PS+ P P
Sbjct: 238 LTPSSRPTLTRSSTPTLTPSSTPTLTPSSTPTLTP 272
Score = 70.9 bits (172), Expect = 2e-12
Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 25/176 (14%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S P++ + P++ P P++ PSN P++ PS+ P+ PS
Sbjct: 52 PTLTPSSPPTLTPSNTPTLT------PCSTPTLTPCSTPTLTPSNTPTLTPSSTPTLTPS 105
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P ++ PS+ P + P P++ P P+ S+ P++ P
Sbjct: 106 STPTLTPSSTP------------TLTPSSTPTLTPSSTPTLTPSSTPTLTRSSTPTLTPS 153
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHP-------PVPHPSTHPSIHPS 246
P+ PS+ P + P P + PS P+ P + P P PS+ P++ PS
Sbjct: 154 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 209
Score = 67.8 bits (164), Expect = 2e-11
Identities = 43/149 (28%), Positives = 73/149 (48%), Gaps = 6/149 (4%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ S+ P++ P P++ PS+ P++ PS+ P+ PS
Sbjct: 132 PTLTPSSTPTLTRSSTPTLT------PSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPS 185
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P + P + PS P+ P P + PS P + PS+ + PS RP
Sbjct: 186 SRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSNTPTLIPSSTPTLTPSSTPTLTPSSRPT 245
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPST 226
+ S+ P+ P P + P P++ PS+
Sbjct: 246 LTRSSTPTLTPSSTPTLTPSSTPTLTPSS 274
>gi|239751395 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 77.8 bits (190), Expect = 2e-14
Identities = 50/176 (28%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ + S+ P++ P P++ PSN P++ PS P+ PS
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P P++ PS+ P++ P++ P P S+ P++ P
Sbjct: 124 NTPTLTPSSTPT----LTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHP-------STHPPTHPPVPHPSTHPSIHPS 246
P+ PS+ P + P P + PS P T P+ P+ PS+ P++ PS
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPS 235
Score = 71.2 bits (173), Expect = 2e-12
Identities = 49/172 (28%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S P++ S P++ P P++ PS+ P++ PS+ P+ PS
Sbjct: 94 PTLTPSSPPTLTPSNTPTLT------PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 147
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P + P + S P+ P P + PS P + PS+ + PS RP
Sbjct: 148 SRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI 207
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP---PTHPPVPHPSTHPSIHPS 246
+ S+ P+ P P + P P++ PS+ P + P PS+ P++ PS
Sbjct: 208 LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 259
Score = 71.2 bits (173), Expect = 2e-12
Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 17/180 (9%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHP----S 133
P + PS P + S+ P++ S+ P++ P P + S+ P++ PS+ P S
Sbjct: 118 PTLTPSNTPTLTPSSTPTLT------PSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRS 171
Query: 134 THPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLI----HPPIHPSIHPPIHPSTHLS 189
+ P++ P P + P + P P++ PS+ P++ P + PS P + PS+ +
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231
Query: 190 THPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP---PTHPPVPHPSTHPSIHPS 246
PS RP + S+ P+ P P + P P++ PS P P++ P PS+ P++ PS
Sbjct: 232 LTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPS 291
Score = 68.9 bits (167), Expect = 9e-12
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 15/171 (8%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIH--IHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTH 135
P + PS P + S+ P++ + S+ P++ P P++ PS+ P++ PS+ P+
Sbjct: 142 PTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201
Query: 136 PSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIR 195
PS P + P++ PS+ P++ P P++ P P S+ P++
Sbjct: 202 PSSRPI------------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLT 249
Query: 196 PPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTHPSIHPS 246
P P+ PS P + P P + PS P T P+ P PS+ P++ PS
Sbjct: 250 PSSTPTLTPSNTPTLTPSNTPTLTPSNTP-TLTPSSTPTLTPSSTPTLTPS 299
Score = 67.0 bits (162), Expect = 4e-11
Identities = 45/144 (31%), Positives = 69/144 (47%), Gaps = 3/144 (2%)
Query: 105 STHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHP 164
S P++ P P++ PS+ P++ PS+ P S P + P P + P + PS P
Sbjct: 5 SNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 64
Query: 165 STHPLIHPPIHPSIHPPIHPSTHL--STHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSI 222
+ P P + PS P + P L S+ P++ P P+ PS P + P P + PS
Sbjct: 65 TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124
Query: 223 HPSTHPPTHPPVPHPSTHPSIHPS 246
P T P+ P PS+ P++ PS
Sbjct: 125 TP-TLTPSSTPTLTPSSTPTLTPS 147
Score = 65.9 bits (159), Expect = 8e-11
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 9/136 (6%)
Query: 120 PSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIH 179
PSN P++ PS+ P+ PS P + P P + P + PS P+ P P + PS
Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63
Query: 180 PPIHPSTHLSTHPSIRPPVHP------STHPSTHPLIHPPIHPPIHPSIHPSTHP---PT 230
P + PS+ + PS P + P S+ P+ P P + P P++ PS P P+
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 231 HPPVPHPSTHPSIHPS 246
+ P PS+ P++ PS
Sbjct: 124 NTPTLTPSSTPTLTPS 139
Score = 62.8 bits (151), Expect = 7e-10
Identities = 42/149 (28%), Positives = 68/149 (45%), Gaps = 6/149 (4%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ S+ P++ P P++ PS+ P++ PS+ P S
Sbjct: 158 PTLTPSSRPILTRSSTPTLT------PSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRS 211
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P + PS P P + PS P + PS + PS P
Sbjct: 212 STPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPST 226
+ PS P+ P P + P P++ PS+
Sbjct: 272 LTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300
>gi|239745904 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 306
Score = 77.8 bits (190), Expect = 2e-14
Identities = 50/176 (28%), Positives = 85/176 (48%), Gaps = 11/176 (6%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ + S+ P++ P P++ PSN P++ PS P+ PS
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P P++ PS+ P++ P++ P P S+ P++ P
Sbjct: 124 NTPTLTPSSTPT----LTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPS 179
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHP-------STHPPTHPPVPHPSTHPSIHPS 246
P+ PS+ P + P P + PS P T P+ P+ PS+ P++ PS
Sbjct: 180 STPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPTLTPS 235
Score = 71.2 bits (173), Expect = 2e-12
Identities = 49/172 (28%), Positives = 81/172 (47%), Gaps = 9/172 (5%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S P++ S P++ P P++ PS+ P++ PS+ P+ PS
Sbjct: 94 PTLTPSSPPTLTPSNTPTLT------PSNTPTLTPSNTPTLTPSSTPTLTPSSTPTLTPS 147
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P + P + S P+ P P + PS P + PS+ + PS RP
Sbjct: 148 SRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPI 207
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP---PTHPPVPHPSTHPSIHPS 246
+ S+ P+ P P + P P++ PS+ P + P PS+ P++ PS
Sbjct: 208 LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPS 259
Score = 71.2 bits (173), Expect = 2e-12
Identities = 51/180 (28%), Positives = 89/180 (49%), Gaps = 17/180 (9%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHP----S 133
P + PS P + S+ P++ S+ P++ P P + S+ P++ PS+ P S
Sbjct: 118 PTLTPSNTPTLTPSSTPTLT------PSSTPTLTPSSRPILTRSSTPTLTPSSRPILTRS 171
Query: 134 THPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLI----HPPIHPSIHPPIHPSTHLS 189
+ P++ P P + P + P P++ PS+ P++ P + PS P + PS+ +
Sbjct: 172 STPTLTPSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRSSTPTLTPSSRPILTPSSTPT 231
Query: 190 THPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHP---PTHPPVPHPSTHPSIHPS 246
PS RP + S+ P+ P P + P P++ PS P P++ P PS+ P++ PS
Sbjct: 232 LTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPTLTPSNTPTLTPSSTPTLTPS 291
Score = 68.9 bits (167), Expect = 9e-12
Identities = 47/171 (27%), Positives = 81/171 (47%), Gaps = 15/171 (8%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIH--IHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTH 135
P + PS P + S+ P++ + S+ P++ P P++ PS+ P++ PS+ P+
Sbjct: 142 PTLTPSSRPILTRSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSSTPTLTPSSTPTLT 201
Query: 136 PSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIR 195
PS P + P++ PS+ P++ P P++ P P S+ P++
Sbjct: 202 PSSRPI------------LTRSSTPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLT 249
Query: 196 PPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTHPSIHPS 246
P P+ PS P + P P + PS P T P+ P PS+ P++ PS
Sbjct: 250 PSSTPTLTPSNTPTLTPSNTPTLTPSNTP-TLTPSSTPTLTPSSTPTLTPS 299
Score = 67.0 bits (162), Expect = 4e-11
Identities = 45/144 (31%), Positives = 69/144 (47%), Gaps = 3/144 (2%)
Query: 105 STHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHP 164
S P++ P P++ PS+ P++ PS+ P S P + P P + P + PS P
Sbjct: 5 SNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTP 64
Query: 165 STHPLIHPPIHPSIHPPIHPSTHL--STHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSI 222
+ P P + PS P + P L S+ P++ P P+ PS P + P P + PS
Sbjct: 65 TLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPSN 124
Query: 223 HPSTHPPTHPPVPHPSTHPSIHPS 246
P T P+ P PS+ P++ PS
Sbjct: 125 TP-TLTPSSTPTLTPSSTPTLTPS 147
Score = 65.9 bits (159), Expect = 8e-11
Identities = 43/136 (31%), Positives = 66/136 (48%), Gaps = 9/136 (6%)
Query: 120 PSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIH 179
PSN P++ PS+ P+ PS P + P P + P + PS P+ P P + PS
Sbjct: 4 PSNTPTLTPSSPPTLTPSSTPTLTPSSQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNT 63
Query: 180 PPIHPSTHLSTHPSIRPPVHP------STHPSTHPLIHPPIHPPIHPSIHPSTHP---PT 230
P + PS+ + PS P + P S+ P+ P P + P P++ PS P P+
Sbjct: 64 PTLTPSSTPTLTPSSTPTLTPQPILTRSSTPTLTPSSPPTLTPSNTPTLTPSNTPTLTPS 123
Query: 231 HPPVPHPSTHPSIHPS 246
+ P PS+ P++ PS
Sbjct: 124 NTPTLTPSSTPTLTPS 139
Score = 62.8 bits (151), Expect = 7e-10
Identities = 42/149 (28%), Positives = 68/149 (45%), Gaps = 6/149 (4%)
Query: 78 PPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPS 137
P + PS P + S+ P++ S+ P++ P P++ PS+ P++ PS+ P S
Sbjct: 158 PTLTPSSRPILTRSSTPTLT------PSSTPTLTPSSTPTLTPSSTPTLTPSSRPILTRS 211
Query: 138 IHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPP 197
P + P P + P + PS P P + PS P + PS + PS P
Sbjct: 212 STPTLTPSSRPILTPSSTPTLTPSSRPILTRSSTPTLTPSSTPTLTPSNTPTLTPSNTPT 271
Query: 198 VHPSTHPSTHPLIHPPIHPPIHPSIHPST 226
+ PS P+ P P + P P++ PS+
Sbjct: 272 LTPSNTPTLTPSSTPTLTPSSTPTLTPSS 300
>gi|169166365 PREDICTED: hypothetical protein [Homo sapiens]
Length = 232
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/148 (32%), Positives = 69/148 (46%), Gaps = 8/148 (5%)
Query: 72 IHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTH 131
IHL+IH IH +H T IH++IH+++ IH +IH H H V T+
Sbjct: 17 IHLYIHVYTCVCIHLYIHVYTCVCIHIYIHVYTCV--CIHTYIHVHTHTYMHTHVCTHTY 74
Query: 132 PSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTH 191
TH H +IH V+ ++ HIH IH VH T+ H H IH ++ + H
Sbjct: 75 MYTHVCTHTYIH--VYTCVYTHIHTCIHMCVHTHTYMYTHVCTHTYIH--VYTCVYTHIH 130
Query: 192 PSIRPPVHPSTHPSTHPLIHPPIHPPIH 219
I VH T+ + I+ +H IH
Sbjct: 131 TCIHMCVH--TYVCMYIYIYICVHVYIH 156
Score = 69.3 bits (168), Expect = 7e-12
Identities = 48/162 (29%), Positives = 74/162 (45%), Gaps = 10/162 (6%)
Query: 68 IHPPIHLH----IHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPF--IHPSVHPS 121
IH IH++ IH IH H MH TH H +++ H TH IH + ++ +H
Sbjct: 41 IHIYIHVYTCVCIHTYIHVHTHTYMH--THVCTHTYMYTHVCTHTYIHVYTCVYTHIHTC 98
Query: 122 NHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPP 181
H VH T+ TH H +IH V+ ++ HIH IH VH I+ I ++
Sbjct: 99 IHMCVHTHTYMYTHVCTHTYIH--VYTCVYTHIHTCIHMCVHTYVCMYIYIYICVHVYIH 156
Query: 182 IHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIH 223
IH + T+ + +H + + IH ++ IH I+
Sbjct: 157 IHMCACIYTYTYVYVYIHTHIYVYMYIYIHIYVYVYIHIHIY 198
Score = 48.5 bits (114), Expect = 1e-05
Identities = 42/164 (25%), Positives = 61/164 (37%), Gaps = 19/164 (11%)
Query: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHP 160
+IH+ H + IH +H +H H T IH +IH IH +IH H
Sbjct: 6 YIHACIHICV--CIHLYIHVYTCVCIHLYIHVYTCVCIHIYIHVYTCVCIHTYIHVHTHT 63
Query: 161 SVHPS--------THPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHP 212
+H TH H IH ++ ++ H H + + TH TH IH
Sbjct: 64 YMHTHVCTHTYMYTHVCTHTYIH--VYTCVYTHIHTCIHMCVHTHTYMYTHVCTHTYIH- 120
Query: 213 PIHPPIHPSIHPSTHPPTHPPV-----PHPSTHPSIHPSYMGCI 251
++ ++ IH H H V + H IH CI
Sbjct: 121 -VYTCVYTHIHTCIHMCVHTYVCMYIYIYICVHVYIHIHMCACI 163
Score = 45.1 bits (105), Expect = 1e-04
Identities = 31/129 (24%), Positives = 59/129 (45%), Gaps = 14/129 (10%)
Query: 68 IHPPIHLHIHPPIHPSIHPPMHSST--HPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPS 125
IH +H H + H H +H T + IH IH+ T+ ++ +I+ VH H
Sbjct: 99 IHMCVHTHTYMYTHVCTHTYIHVYTCVYTHIHTCIHMCVHTYVCMYIYIYICVHVYIH-- 156
Query: 126 VHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPS 185
+H T+ ++ +IH ++ ++++IH ++ +H IH ++ IH
Sbjct: 157 IHMCACIYTYTYVYVYIHTHIYVYMYIYIHIYVYVYIH----------IHIYVYVYIHIH 206
Query: 186 THLSTHPSI 194
TH+ + I
Sbjct: 207 THICRNSDI 215
>gi|119964721 fer (fps/fes related) tyrosine kinase [Homo sapiens]
Length = 822
Score = 71.6 bits (174), Expect = 1e-12
Identities = 34/91 (37%), Positives = 54/91 (59%)
Query: 368 VAPTEEQLRQEPWYHGRMSRRAAERMLRADGDFLVRDSVTNPGQYVLTGMHAGQPKHLLL 427
++ +E+ L ++ WYHG + R A+ +L+ GDFLVR+S PG+YVL+ GQ +H ++
Sbjct: 448 ISISEKPLAEQDWYHGAIPRIEAQELLKKQGDFLVRESHGKPGEYVLSVYSDGQRRHFII 507
Query: 428 VDPEGVVRTKDVLFESISHLIDHHLQNGQPI 458
+ + R + F +I LIDHH Q I
Sbjct: 508 QYVDNMYRFEGTGFSNIPQLIDHHYTTKQVI 538
>gi|169166886 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 202
Score = 71.2 bits (173), Expect = 2e-12
Identities = 42/156 (26%), Positives = 75/156 (48%), Gaps = 4/156 (2%)
Query: 68 IHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVH 127
I+ IH+H++ + IH +++ TH I+++ HIH T+ SIH I+ +H + +H
Sbjct: 23 IYTYIHIHLYTYTYTYIHIRLYTYTHIYIYVYTHIHIYTYTSIHVCIYTHIHVCVYTHIH 82
Query: 128 PSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTH 187
+ H ++ IH V+ IH+ ++ IH V+ H ++ IH H +
Sbjct: 83 VCVYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHTCMCIH--THTCMY 140
Query: 188 LSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIH 223
+ T+ I ++ TH + IH I+ H IH
Sbjct: 141 IHTYMYIHTYIYVYTHICIYTYIHICIY--THMYIH 174
Score = 67.4 bits (163), Expect = 3e-11
Identities = 41/165 (24%), Positives = 75/165 (45%), Gaps = 8/165 (4%)
Query: 69 HPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF------IHIHSSTHPSIHPFIHPSVHPSN 122
H I+++++ IH +H T+ IHL+ IHI T+ I+ +++ +H
Sbjct: 2 HIHIYIYVYTHIHIYTRTSIHIYTYIHIHLYTYTYTYIHIRLYTYTHIYIYVYTHIHIYT 61
Query: 123 HPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPI 182
+ S+H + H ++ IH V+ IH+ ++ IH V+ H ++ IH ++ I
Sbjct: 62 YTSIHVCIYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHI 121
Query: 183 HPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTH 227
H + TH + H + T+ IH I+ H I+ H
Sbjct: 122 HVCVY--THTCMCIHTHTCMYIHTYMYIHTYIYVYTHICIYTYIH 164
Score = 54.3 bits (129), Expect = 2e-07
Identities = 34/125 (27%), Positives = 58/125 (46%), Gaps = 14/125 (11%)
Query: 67 SIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSV 126
SIH I+ HIH ++ IH ++ TH + ++ HIH + IH ++ +H + +
Sbjct: 64 SIHVCIYTHIHVCVYTHIHVCVY--THIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHI 121
Query: 127 HPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPST 186
H + T IH H +++H + IH ++ TH I+ IH I+ T
Sbjct: 122 HVCVYTHTCMCIH------THTCMYIHTYMYIHTYIYVYTHICIYTYIHICIY------T 169
Query: 187 HLSTH 191
H+ H
Sbjct: 170 HMYIH 174
Score = 47.8 bits (112), Expect = 2e-05
Identities = 29/139 (20%), Positives = 56/139 (40%), Gaps = 20/139 (14%)
Query: 93 HPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHL 152
H I+++ HIH T SIH + + +H ++ T+ H ++ + H ++ H+
Sbjct: 4 HIYIYVYTHIHIYTRTSIHIYTYIHIH------LYTYTYTYIHIRLYTYTHIYIYVYTHI 57
Query: 153 HIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHP 212
HI+ + IH I+ IH + H + +H + H ++
Sbjct: 58 HIYT--------------YTSIHVCIYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYT 103
Query: 213 PIHPPIHPSIHPSTHPPTH 231
IH ++ IH + H
Sbjct: 104 HIHVCVYTHIHVCVYTHIH 122
Score = 37.4 bits (85), Expect = 0.030
Identities = 27/117 (23%), Positives = 51/117 (43%), Gaps = 5/117 (4%)
Query: 130 THPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLS 189
TH + ++ IH IH++ + IH ++ T+ IH ++ H I+ TH+
Sbjct: 1 THIHIYIYVYTHIHIYTRTSIHIYTY--IHIHLYTYTYTYIHIRLYTYTHIYIYVYTHIH 58
Query: 190 --THPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTHPPTHPPVPHPSTHPSIH 244
T+ SI ++ H + IH ++ IH ++ H + + H + IH
Sbjct: 59 IYTYTSIHVCIYTHIHVCVYTHIHVCVYTHIHVCVYTHIHVCVYTHI-HVCVYTHIH 114
>gi|124249376 proline rich 21 [Homo sapiens]
Length = 389
Score = 68.6 bits (166), Expect = 1e-11
Identities = 67/233 (28%), Positives = 101/233 (43%), Gaps = 42/233 (18%)
Query: 43 THGPHSSGFQPHNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPP--MHSSTHPSIHLFI 100
THGP S P V+ + + PP L H P +HP +H+S+ ++ +
Sbjct: 112 THGPSSMPLHPRPF----VHASSPTALPPC-LFTHGPSSMPLHPRPFLHASSPTALPPCL 166
Query: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPS--THPSTHPSIHP--FIH---PPVHPPIHLH 153
H + +HP P VH S+ ++ P TH + +HP F+H P PP L
Sbjct: 167 FTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPC-LF 223
Query: 154 IHPPIHPSVHPSTHPLIHPPIHPSIHPPI--HPSTHLSTHPSIRPPVHPSTHPSTHPLI- 210
H P +HP P +H ++ P + H + + HP RP +H S+ + P +
Sbjct: 224 THGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHASSPTALRPCLF 279
Query: 211 -HPPIHPPIHPS--IHPS----------THPPT----HP-PVPHPSTHPSIHP 245
H P P+HP +H S TH P+ HP P H S+ S+HP
Sbjct: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSSTSLHP 332
Score = 62.8 bits (151), Expect = 7e-10
Identities = 64/226 (28%), Positives = 97/226 (42%), Gaps = 47/226 (20%)
Query: 65 AASIHPPIHLHIHPPIHPSIHPPM--HSSTHPSIHLFIHIHSSTHPSIHP--FIH----- 115
+ ++HP +H P+ ++HP + H + ++H H S+ S+HP F H
Sbjct: 33 STALHPWPFIHGSSPM--ALHPRLFTHGPSSTALHPCPFTHGSSPMSLHPRLFTHSPSSM 90
Query: 116 -----PSVHPSNHPSVHPS--THPSTHPSIH--PFIH---PPVHPPIHLHIHPPIHPSVH 163
P VH S+ ++ P TH + +H PF+H P PP L H P +H
Sbjct: 91 PLHPRPFVHASSPTALRPCLFTHGPSSMPLHPRPFVHASSPTALPPC-LFTHGPSSMPLH 149
Query: 164 PSTHPLIHPPIHPSIHPP---IHPSTHLSTHPSIRPPVHPSTHPSTHPLI--HPPIHPPI 218
P P +H P+ PP H + + HP RP VH S+ + P + H P P+
Sbjct: 150 P--RPFLHAS-SPTALPPCLFTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPL 204
Query: 219 HPS--IHPS----------THPPTHPPV-PHPSTHPSIHPSYMGCI 251
HP +H S TH P+ P+ P P H S + C+
Sbjct: 205 HPRPFVHASSPTALPPCLFTHGPSSMPLHPRPFVHASSPTALRPCL 250
Score = 58.9 bits (141), Expect = 1e-08
Identities = 52/192 (27%), Positives = 79/192 (41%), Gaps = 41/192 (21%)
Query: 43 THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99
THGP S P + S + H P + +HP P +H+S+ ++
Sbjct: 168 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP------RPFVHASSPTALPPC 221
Query: 100 IHIHSSTHPSIHPFIHPSVHPSNHPSVHPS--THPSTHPSIHP--FIHPP---------- 145
+ H + +HP P VH S+ ++ P TH + +HP F+H
Sbjct: 222 LFTHGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHPRPFLHASSPTALRPCLF 279
Query: 146 VHPPIHLHIHPPIHPSVHPSTHPLIHP----------PIHPSIHPPIHPSTHLSTHPSIR 195
H P + +HP P VH S+ + P P+HP P +H S+ S HP R
Sbjct: 280 THGPSSMPLHP--RPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--R 333
Query: 196 PPVHPSTHPSTH 207
P +H S+ S H
Sbjct: 334 PFIHASSSKSLH 345
Score = 56.2 bits (134), Expect = 6e-08
Identities = 61/195 (31%), Positives = 84/195 (43%), Gaps = 32/195 (16%)
Query: 80 IHPSIHPPMHSSTHPSI--HLFIHIHSST-HPSIHPFIHPSVHPSNHP----------SV 126
+HP P +H + + LF H S+ HP PFIH S + HP ++
Sbjct: 9 LHP--RPFIHGFSFTTFLQQLFPHGSSTALHP--WPFIHGSSPMALHPRLFTHGPSSTAL 64
Query: 127 HPS--THPSTHPSIHP--FIHPPVHPPIHLHIHPPIHPSVHPSTHPLI--HPPIHPSIHP 180
HP TH S+ S+HP F H P P LH P +H S + P + H P +HP
Sbjct: 65 HPCPFTHGSSPMSLHPRLFTHSPSSMP--LHPRPFVHASSPTALRPCLFTHGPSSMPLHP 122
Query: 181 PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPS---THPPTHPPV-PH 236
P H S+ P+ PP + PS+ PL P P+ P TH P+ P+ P
Sbjct: 123 --RPFVHASS-PTALPPCLFTHGPSSMPLHPRPFLHASSPTALPPCLFTHGPSSMPLHPR 179
Query: 237 PSTHPSIHPSYMGCI 251
P H S + C+
Sbjct: 180 PFVHASSPTALRPCL 194
Score = 42.4 bits (98), Expect = 0.001
Identities = 38/133 (28%), Positives = 50/133 (37%), Gaps = 29/133 (21%)
Query: 43 THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99
THGP S P + S + H P + +HP P +H ++ P LF
Sbjct: 224 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFLHASSPTALRPC--LF 279
Query: 100 IHIHSSTHPSIHPFIHPS------------------VHPSNHPSVHPSTHPSTHPSIHPF 141
H SS PF+H S +HP P VH S+ S HP PF
Sbjct: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--RPF 335
Query: 142 IHPPVHPPIHLHI 154
IH +HL +
Sbjct: 336 IHASSSKSLHLRL 348
Score = 32.7 bits (73), Expect = 0.74
Identities = 24/78 (30%), Positives = 31/78 (39%), Gaps = 7/78 (8%)
Query: 43 THGPHSSGFQPH---NRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLF 99
THGP S P + S + H P + +HP P +H +S HP F
Sbjct: 280 THGPSSMPLHPRPFVHASSPTALRPCLFTHGPSSMPLHP--RPFVHASSSTSLHP--RPF 335
Query: 100 IHIHSSTHPSIHPFIHPS 117
IH SS + F H S
Sbjct: 336 IHASSSKSLHLRLFSHSS 353
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 64.7 bits (156), Expect = 2e-10
Identities = 45/158 (28%), Positives = 57/158 (36%), Gaps = 19/158 (12%)
Query: 108 PSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTH 167
P H P++HP PS HP HPS HP + P P H PP+H P H
Sbjct: 242 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH 301
Query: 168 PLIHPPI--HPSIHPPIHPSTHLS--------------THPSIRPPVHPSTHPSTHPLIH 211
L P+ HP P S H S++ P S S P
Sbjct: 302 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 361
Query: 212 PPIHPPIHPSIHPSTHPPTHPPVPH-PSTHPSIHPSYM 248
P+ P P P PP P+P P+ HP ++
Sbjct: 362 QPLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 397
Score = 59.7 bits (143), Expect = 6e-09
Identities = 56/191 (29%), Positives = 65/191 (34%), Gaps = 48/191 (25%)
Query: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPST----HPSIHPFIHPPVH--------- 147
H H P++HP PS HP HPS HP P T PS PP+H
Sbjct: 243 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 302
Query: 148 ---PPIHLHIHPP----IHPSVHPSTHPLIHPPI----HPSIHPPIHPSTHLSTHPSIRP 196
P+ H PP + P PL P H S+ P S S P
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
Query: 197 PVHPSTHPSTHPLIHPPIHPPIHPSIHPSTH--------------------PPTHPPVPH 236
P+ P+ P P I PP PI P H PP P+
Sbjct: 363 PLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
Query: 237 PSTH--PSIHP 245
STH PS HP
Sbjct: 421 LSTHHPPSAHP 431
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 4/157 (2%)
Query: 82 PSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPF 141
PSI P + + + + P++ + PS+ P P P+ P+
Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQL-PTPGPTPSAT 217
Query: 142 IHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPS 201
PP P P P + P H P++HP PS H HPS PP+ P
Sbjct: 218 AVPPQGSPTASQA--PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 275
Query: 202 THPSTHPLIHPPIHPPIHPSIHPSTHP-PTHPPVPHP 237
T + P PP+H P H P + HP
Sbjct: 276 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 312
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/204 (25%), Positives = 65/204 (31%), Gaps = 18/204 (8%)
Query: 46 PHSSGFQPHNRSG---LRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHI 102
P G P G L + AA H + L S PP P+ HI
Sbjct: 315 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 374
Query: 103 HSSTHPSIHPFIHPSVHPSNHPSVHPSTHP-STHPSIHPFIHPPVHPPIH---LHIHPPI 158
I P H HP P S + ++ P PP P+ H P
Sbjct: 375 KPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSA 429
Query: 159 HP---SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIH 215
HP + P + PL P P P + S +L P+ PP P P
Sbjct: 430 HPPPLQLMPQSQPLPSSPAQP---PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 486
Query: 216 PPIHPSIHPSTHPPTHPPVPHPST 239
P P I P T P T P P T
Sbjct: 487 PGGPPPITPPTCPSTSTPPAGPGT 510
Score = 40.4 bits (93), Expect = 0.004
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 66/222 (29%)
Query: 76 IHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPF--IHPSVHPSNH-------PSV 126
+ PP +HP + H + H + I + P HPF HP ++P P +
Sbjct: 775 VKPPELDPLHPAANPMEHFARHSALTIPPTAGP--HPFASFHPGLNPLERERLALAGPQL 832
Query: 127 HPS-----------THPSTHPSI---------------HPFIHPPVHPPIHLHIHPPIHP 160
P H S+ H H +H +HLH P+H
Sbjct: 833 RPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQ 892
Query: 161 SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHP 220
HPL+ P+ HL+ R P P T P +PL+ P
Sbjct: 893 GSAGPVHPLV---------DPLTAGPHLA-----RFPYPPGTLP--NPLLGQP------- 929
Query: 221 SIHPSTHPPTHPPV---PHPSTHPSIHPSYMGCIEVLRSMRS 259
P H PV P+P P P M L++M +
Sbjct: 930 ---PHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHA 968
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 64.7 bits (156), Expect = 2e-10
Identities = 45/158 (28%), Positives = 57/158 (36%), Gaps = 19/158 (12%)
Query: 108 PSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTH 167
P H P++HP PS HP HPS HP + P P H PP+H P H
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH 855
Query: 168 PLIHPPI--HPSIHPPIHPSTHLS--------------THPSIRPPVHPSTHPSTHPLIH 211
L P+ HP P S H S++ P S S P
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915
Query: 212 PPIHPPIHPSIHPSTHPPTHPPVPH-PSTHPSIHPSYM 248
P+ P P P PP P+P P+ HP ++
Sbjct: 916 QPLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 951
Score = 59.7 bits (143), Expect = 6e-09
Identities = 56/191 (29%), Positives = 65/191 (34%), Gaps = 48/191 (25%)
Query: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPST----HPSIHPFIHPPVH--------- 147
H H P++HP PS HP HPS HP P T PS PP+H
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 856
Query: 148 ---PPIHLHIHPP----IHPSVHPSTHPLIHPPI----HPSIHPPIHPSTHLSTHPSIRP 196
P+ H PP + P PL P H S+ P S S P
Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916
Query: 197 PVHPSTHPSTHPLIHPPIHPPIHPSIHPSTH--------------------PPTHPPVPH 236
P+ P+ P P I PP PI P H PP P+
Sbjct: 917 PLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974
Query: 237 PSTH--PSIHP 245
STH PS HP
Sbjct: 975 LSTHHPPSAHP 985
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 4/157 (2%)
Query: 82 PSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPF 141
PSI P + + + + P++ + PS+ P P P+ P+
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQL-PTPGPTPSAT 771
Query: 142 IHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPS 201
PP P P P + P H P++HP PS H HPS PP+ P
Sbjct: 772 AVPPQGSPTASQA--PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829
Query: 202 THPSTHPLIHPPIHPPIHPSIHPSTHP-PTHPPVPHP 237
T + P PP+H P H P + HP
Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/204 (25%), Positives = 65/204 (31%), Gaps = 18/204 (8%)
Query: 46 PHSSGFQPHNRSG---LRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHI 102
P G P G L + AA H + L S PP P+ HI
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 103 HSSTHPSIHPFIHPSVHPSNHPSVHPSTHP-STHPSIHPFIHPPVHPPIH---LHIHPPI 158
I P H HP P S + ++ P PP P+ H P
Sbjct: 929 KPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSA 983
Query: 159 HP---SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIH 215
HP + P + PL P P P + S +L P+ PP P P
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQP---PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 216 PPIHPSIHPSTHPPTHPPVPHPST 239
P P I P T P T P P T
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGT 1064
Score = 40.4 bits (93), Expect = 0.004
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 66/222 (29%)
Query: 76 IHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPF--IHPSVHPSNH-------PSV 126
+ PP +HP + H + H + I + P HPF HP ++P P +
Sbjct: 1329 VKPPELDPLHPAANPMEHFARHSALTIPPTAGP--HPFASFHPGLNPLERERLALAGPQL 1386
Query: 127 HPS-----------THPSTHPSI---------------HPFIHPPVHPPIHLHIHPPIHP 160
P H S+ H H +H +HLH P+H
Sbjct: 1387 RPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQ 1446
Query: 161 SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHP 220
HPL+ P+ HL+ R P P T P +PL+ P
Sbjct: 1447 GSAGPVHPLV---------DPLTAGPHLA-----RFPYPPGTLP--NPLLGQP------- 1483
Query: 221 SIHPSTHPPTHPPV---PHPSTHPSIHPSYMGCIEVLRSMRS 259
P H PV P+P P P M L++M +
Sbjct: 1484 ---PHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHA 1522
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 64.7 bits (156), Expect = 2e-10
Identities = 45/158 (28%), Positives = 57/158 (36%), Gaps = 19/158 (12%)
Query: 108 PSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTH 167
P H P++HP PS HP HPS HP + P P H PP+H P H
Sbjct: 796 PHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPH 855
Query: 168 PLIHPPI--HPSIHPPIHPSTHLS--------------THPSIRPPVHPSTHPSTHPLIH 211
L P+ HP P S H S++ P S S P
Sbjct: 856 SLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPRE 915
Query: 212 PPIHPPIHPSIHPSTHPPTHPPVPH-PSTHPSIHPSYM 248
P+ P P P PP P+P P+ HP ++
Sbjct: 916 QPLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHL 951
Score = 59.7 bits (143), Expect = 6e-09
Identities = 56/191 (29%), Positives = 65/191 (34%), Gaps = 48/191 (25%)
Query: 101 HIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPST----HPSIHPFIHPPVH--------- 147
H H P++HP PS HP HPS HP P T PS PP+H
Sbjct: 797 HTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 856
Query: 148 ---PPIHLHIHPP----IHPSVHPSTHPLIHPPI----HPSIHPPIHPSTHLSTHPSIRP 196
P+ H PP + P PL P H S+ P S S P
Sbjct: 857 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 916
Query: 197 PVHPSTHPSTHPLIHPPIHPPIHPSIHPSTH--------------------PPTHPPVPH 236
P+ P+ P P I PP PI P H PP P+
Sbjct: 917 PLPPA--PLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 974
Query: 237 PSTH--PSIHP 245
STH PS HP
Sbjct: 975 LSTHHPPSAHP 985
Score = 47.8 bits (112), Expect = 2e-05
Identities = 40/157 (25%), Positives = 57/157 (36%), Gaps = 4/157 (2%)
Query: 82 PSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPF 141
PSI P + + + + P++ + PS+ P P P+ P+
Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQL-PTPGPTPSAT 771
Query: 142 IHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPS 201
PP P P P + P H P++HP PS H HPS PP+ P
Sbjct: 772 AVPPQGSPTASQA--PNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPL 829
Query: 202 THPSTHPLIHPPIHPPIHPSIHPSTHP-PTHPPVPHP 237
T + P PP+H P H P + HP
Sbjct: 830 TGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHP 866
Score = 43.5 bits (101), Expect = 4e-04
Identities = 53/204 (25%), Positives = 65/204 (31%), Gaps = 18/204 (8%)
Query: 46 PHSSGFQPHNRSG---LRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHI 102
P G P G L + AA H + L S PP P+ HI
Sbjct: 869 PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHI 928
Query: 103 HSSTHPSIHPFIHPSVHPSNHPSVHPSTHP-STHPSIHPFIHPPVHPPIH---LHIHPPI 158
I P H HP P S + ++ P PP P+ H P
Sbjct: 929 KPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPP---PPALKPLSSLSTHHPPSA 983
Query: 159 HP---SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIH 215
HP + P + PL P P P + S +L P+ PP P P
Sbjct: 984 HPPPLQLMPQSQPLPSSPAQP---PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFV 1040
Query: 216 PPIHPSIHPSTHPPTHPPVPHPST 239
P P I P T P T P P T
Sbjct: 1041 PGGPPPITPPTCPSTSTPPAGPGT 1064
Score = 40.4 bits (93), Expect = 0.004
Identities = 51/222 (22%), Positives = 73/222 (32%), Gaps = 66/222 (29%)
Query: 76 IHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPF--IHPSVHPSNH-------PSV 126
+ PP +HP + H + H + I + P HPF HP ++P P +
Sbjct: 1329 VKPPELDPLHPAANPMEHFARHSALTIPPTAGP--HPFASFHPGLNPLERERLALAGPQL 1386
Query: 127 HPS-----------THPSTHPSI---------------HPFIHPPVHPPIHLHIHPPIHP 160
P H S+ H H +H +HLH P+H
Sbjct: 1387 RPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQ 1446
Query: 161 SVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHP 220
HPL+ P+ HL+ R P P T P +PL+ P
Sbjct: 1447 GSAGPVHPLV---------DPLTAGPHLA-----RFPYPPGTLP--NPLLGQP------- 1483
Query: 221 SIHPSTHPPTHPPV---PHPSTHPSIHPSYMGCIEVLRSMRS 259
P H PV P+P P P M L++M +
Sbjct: 1484 ---PHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHA 1522
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 63.2 bits (152), Expect = 5e-10
Identities = 64/222 (28%), Positives = 94/222 (42%), Gaps = 32/222 (14%)
Query: 43 THGPHSSGFQPHNRSG-LRVNKGAASIHPPIH------LHIHPPIHPS-IH--PPM-HSS 91
TH P P +R L G A P+ + I PP HP+ +H PP+ H
Sbjct: 361 THPPLPPAHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRP 420
Query: 92 THPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIH 151
P ++ S+T + + S+ S+ + PS + ++ P PP H P H
Sbjct: 421 PPPPPSSYMTGMSTTSSYMSGEGYQSLQ-----SMMKTEGPS-YGALPPAYGPPAHLPYH 474
Query: 152 LHIHPPIHPSVHPSTHPLIHPPIHPSIHPPI--HPSTHLSTHPSIRPPVHPSTHPSTHPL 209
H++PP P P PP P+I PP +P + +P+ PP P P TH +
Sbjct: 475 PHVYPPNPPPPPVPPPPASFPP--PAIPPPTPGYPPPPPTYNPNFPPP--PPRLPPTHAV 530
Query: 210 IHPPIHPPIHPSIHPSTHPPT------HPPVPHPSTHPSIHP 245
P HPP + P+++PP PPVP P P + P
Sbjct: 531 ---PPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPPGMPP 569
Score = 60.1 bits (144), Expect = 4e-09
Identities = 49/167 (29%), Positives = 68/167 (40%), Gaps = 14/167 (8%)
Query: 66 ASIHPPIHL-HIHPPIHPSIHPPMHSST--------HPSIHLFIHIHSSTHPSIHPFIHP 116
A +H P L H PP PS + S+T + S+ + ++ ++ P P
Sbjct: 408 APVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGP 467
Query: 117 SVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHP 176
H HP V+P P P PP P +PP P+ +P+ P PP P
Sbjct: 468 PAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPP--PPPRLP 525
Query: 177 SIHP-PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSI 222
H P HP L P+ PP P+ P P + PPI PP P +
Sbjct: 526 PTHAVPPHPPPGLGLPPASYPP--PAVPPGGQPPVPPPIPPPGMPPV 570
Score = 45.1 bits (105), Expect = 1e-04
Identities = 43/153 (28%), Positives = 56/153 (36%), Gaps = 43/153 (28%)
Query: 133 STHPSIHPFIHPPVH--PPI-------------------HLHIHPPIHPSVHPSTHPLIH 171
+THP + P HPP PP+ + I PP HP+ PL H
Sbjct: 360 TTHPPLPP-AHPPPDRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPH 418
Query: 172 PPIHPSIHPPIHPSTHLSTHPSIRP---------------PVHPSTHPSTHPLIHPPIHP 216
P P PP T +ST S P + + P+ P H P HP
Sbjct: 419 RPPPP---PPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHP 475
Query: 217 PIHPSIHPSTHPPTHPPVPHPSTHPSIHPSYMG 249
++P P+ PP PP P P+I P G
Sbjct: 476 HVYP---PNPPPPPVPPPPASFPPPAIPPPTPG 505
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 62.8 bits (151), Expect = 7e-10
Identities = 55/201 (27%), Positives = 72/201 (35%), Gaps = 15/201 (7%)
Query: 71 PIHLHIHPPIHPSIHPP--MHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHP 128
P HL + P PP + +S+HP + P+ + V P P V P
Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERP-VRP 530
Query: 129 STHPSTHPSIHPFIHP------PVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPI 182
+ P I F P P PP + P P + T P + P+HP + PP
Sbjct: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPH 590
Query: 183 HPSTHLSTHPSIRPPVHPSTHPSTH--PLIH--PPIHPPIHPSIHPSTHPPTHPPVPHPS 238
P PP H H H P H PP HPP HP H H H VP P
Sbjct: 591 QPQPQQPQQQP--PPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPP 648
Query: 239 THPSIHPSYMGCIEVLRSMRS 259
P P + ++ + S
Sbjct: 649 LMPMSQPQFRPHVQTAQPQAS 669
Score = 35.4 bits (80), Expect = 0.11
Identities = 51/206 (24%), Positives = 68/206 (33%), Gaps = 29/206 (14%)
Query: 63 KGAASIHPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSN 122
+G H P L PP+ P PP I S P + P HP +
Sbjct: 298 RGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQ-----PIRSLFQPQPLQPLLPVQHP-H 351
Query: 123 HPSVHPSTH--PSTHPSIHPFIHPPVHP--PIHLHIHPPIHPS-VHPSTHPLIHPPI--H 175
HPS H P PPV P P ++HI+P + V P PL+ P
Sbjct: 352 HPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPR 411
Query: 176 PSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIH-------PPIHPPIHPSIHPSTHP 228
P++ P P + P + + P PL P P +
Sbjct: 412 PAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRF 471
Query: 229 PTH---------PPVPHPSTHPSIHP 245
P+H PP P P+ S HP
Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHP 497
Score = 35.4 bits (80), Expect = 0.11
Identities = 19/52 (36%), Positives = 20/52 (38%), Gaps = 5/52 (9%)
Query: 69 HPPIHLHIHPPIHPSIHPPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHP 120
H P H PP HP HPP H H HL S P + P P P
Sbjct: 613 HQPPPQHQPPPQHPPQHPPQHQHHHHHHHL-----SVPPPPLMPMSQPQFRP 659
Score = 33.9 bits (76), Expect = 0.33
Identities = 23/63 (36%), Positives = 26/63 (41%), Gaps = 9/63 (14%)
Query: 70 PPIHLHIHPPIH--PSIH--PPMHSSTHPSIHLFIHIHSSTHPSIHPFIHPSVHPSNHPS 125
PP H H P H P H PP H HP H H H H S+ P P + P + P
Sbjct: 602 PPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQ--HHHHHHHLSVPP---PPLMPMSQPQ 656
Query: 126 VHP 128
P
Sbjct: 657 FRP 659
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 62.8 bits (151), Expect = 7e-10
Identities = 69/256 (26%), Positives = 86/256 (33%), Gaps = 43/256 (16%)
Query: 25 SSEALGTVRCHCWCPHNGTHGPHSSGFQPHNRSGLRVN-----KGAASIHPPIHLHIHPP 79
SS A T H H +HG G P +S L+ +G PP P
Sbjct: 1232 SSSASSTHHHHHHHHHGHSHG--GLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPS 1289
Query: 80 IHP------------SIHPPMHSSTHPSIHLFIHIHSSTH-PSIHPFIHPSVHPSNHPSV 126
+ P SI PP S+ H H H P + P P
Sbjct: 1290 LPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGG 1349
Query: 127 HPSTHPSTHPSIH------PFIHP-PVHPPIH--------LHIHPPIHPSVHPSTHPLIH 171
HP P +H P P P HPP H HP + P+ + P
Sbjct: 1350 HPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSR 1409
Query: 172 PPIHPSIHP-----PIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIHPST 226
PP HP P+ P + + HPS P PS H PL H P+H S P T
Sbjct: 1410 PPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPTSPHGPLHASGPPGT 1469
Query: 227 HPPTHPPVPHPSTHPS 242
+PP +P PS
Sbjct: 1470 ---ANPPSANPKAKPS 1482
>gi|59938776 cAMP responsive element binding protein 5 isoform delta
[Homo sapiens]
Length = 369
Score = 61.6 bits (148), Expect = 1e-09
Identities = 50/164 (30%), Positives = 70/164 (42%), Gaps = 22/164 (13%)
Query: 42 GTHGPHSSG------FQP-HNRSGLRVNKGAASIHPPIHLHIHPPIHPSIHPPMHSSTHP 94
G GP+ S QP H+ + +R+ K A + HP + + + M S
Sbjct: 71 GMQGPNLSNPCASPQVQPMHSEAKMRL-KAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQ 129
Query: 95 SIHLFIHIHSSTHPSIHPFIHPSVHPSNHPSVHPSTHPSTHPSIHPFIHPPVHPPIHLHI 154
+ H +H H H ++ P HP H HP+ HP HP H H HP H HLH
Sbjct: 130 TPHHHMHSHPHQHQTLPPH-HPYPHQHQHPAHHP--HPQPH---HQQNHPHHHSHSHLHA 183
Query: 155 HPPIHPSVHPSTHPLIHPPIHPSIHPPIHPST-HLSTHPSIRPP 197
HP H T P HPP+H + P+T + +I+PP
Sbjct: 184 HP-----AHHQTSP--HPPLHTGNQAQVSPATQQMQPTQTIQPP 220
Score = 59.7 bits (143), Expect = 6e-09
Identities = 48/166 (28%), Positives = 66/166 (39%), Gaps = 29/166 (17%)
Query: 77 HPPIHPSIHPPMHSSTHPSIHLFIHIHSS--THPSIHPFIHPSVHPSNHPSVHPSTHPST 134
+P P + P MHS + + H + ++ +++ H + P H +
Sbjct: 79 NPCASPQVQP-MHSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHS 137
Query: 135 HPSIHPFIHPPVHPPIHLHIHPPIHPSVHPSTHPLIHPPIHPSIHPPIHPSTHLSTHPSI 194
HP H + PP HP H H HP HP HP H H HP H +HL HP+
Sbjct: 138 HPHQHQTL-PPHHPYPHQHQHPAHHP--HPQPH-------HQQNHPHHHSHSHLHAHPA- 186
Query: 195 RPPVHPSTHPSTHPLIHPPIHPPIHPSIHPSTH--PPT---HPPVP 235
H T P HPP+H + P+T PT PP P
Sbjct: 187 ----HHQTSP------HPPLHTGNQAQVSPATQQMQPTQTIQPPQP 222
Score = 52.4 bits (124), Expect = 9e-07
Identities = 42/132 (31%), Positives = 53/132 (40%), Gaps = 17/132 (12%)
Query: 3 HVELGWRRVAVMEGFPHKMPGGSSEALGTVRCHCWCPHNGT--HGPHSSGFQPHNRSGLR 60
H E R A + P M G+ +G + + T H HS PH L
Sbjct: 90 HSEAKMRLKAALTHHPAAMSNGNMNTMGHMMEMMGSRQDQTPHHHMHS---HPHQHQTLP 146
Query: 61 VNKGAASIHPPIHLHIHPPIHPSIHP-PMHSSTHPSIHLFIHIHSSTHPSIHPFI-HPSV 118
+ HP H H HP HP HP P H HP H H+H+ HP+ H HP +
Sbjct: 147 PH------HPYPHQHQHPAHHP--HPQPHHQQNHPHHHSHSHLHA--HPAHHQTSPHPPL 196
Query: 119 HPSNHPSVHPST 130
H N V P+T
Sbjct: 197 HTGNQAQVSPAT 208
Score = 49.3 bits (116), Expect = 8e-06
Identities = 28/77 (36%), Positives = 31/77 (40%), Gaps = 10/77 (12%)
Query: 164 PSTHPLIHPPIHPSIHPPIHPSTHLSTHPSIRPPVHPSTHPSTHPLIHPPIHPPIHPSIH 223
P H HP H ++ PP HP H HP+ P HP H H HP H H
Sbjct: 131 PHHHMHSHPHQHQTL-PPHHPYPHQHQHPAHHP------HPQPH---HQQNHPHHHSHSH 180
Query: 224 PSTHPPTHPPVPHPSTH 240
HP H PHP H
Sbjct: 181 LHAHPAHHQTSPHPPLH 197
Score = 48.9 bits (115), Expect = 1e-05
Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 6/67 (8%)
Query: 184 PSTHLSTHP---SIRPPVHPSTHPSTHPLIHP---PIHPPIHPSIHPSTHPPTHPPVPHP 237
P H+ +HP PP HP H HP HP P H HP H +H HP
Sbjct: 131 PHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHPHPQPHHQQNHPHHHSHSHLHAHPAHHQT 190
Query: 238 STHPSIH 244
S HP +H
Sbjct: 191 SPHPPLH 197
Score = 31.6 bits (70), Expect = 1.6
Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 2/32 (6%)
Query: 216 PPIHPSIHPSTHP--PTHPPVPHPSTHPSIHP 245
P H HP H P H P PH HP+ HP
Sbjct: 131 PHHHMHSHPHQHQTLPPHHPYPHQHQHPAHHP 162
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.137 0.459
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,720,253
Number of Sequences: 37866
Number of extensions: 1731121
Number of successful extensions: 20463
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 262
Number of HSP's successfully gapped in prelim test: 634
Number of HSP's that attempted gapping in prelim test: 9021
Number of HSP's gapped (non-prelim): 4838
length of query: 475
length of database: 18,247,518
effective HSP length: 106
effective length of query: 369
effective length of database: 14,233,722
effective search space: 5252243418
effective search space used: 5252243418
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.