Guide to the Human Genome
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Name: SHC3 Sequence: fasta or formatted (594aa) NCBI GI: 224586793
Description:

src homology 2 domain-containing transforming protein C3

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.3         55           3
 C cysteine            1.5          9           2
 D aspartate           5.7         34           2
 E glutamate           5.1         30           3
 F phenylalanine       2.5         15           1
 G glycine             8.1         48           4
 H histidine           3.0         18           2
 I isoleucine          3.5         21           2
 K lysine              5.4         32           2
 L leucine             9.3         55           3
 M methionine          2.0         12           1
 N asparagine          2.0         12           1
 P proline             8.8         52           3
 Q glutamine           4.2         25           2
 R arginine            6.2         37           2
 S serine             10.6         63           3
 T threonine           4.9         29           2
 V valine              4.9         29           2
 W tryptophan          0.7          4           1
 Y tyrosine            2.4         14           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   src homology 2 domain-containing transforming prote... 
SHC1                  0.405   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.404   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.391   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.391   SHC (Src homology 2 domain containing) transforming ...
SHC2                  0.371   SHC (Src homology 2 domain containing) transforming...
SHC4                  0.364   rai-like protein 
LOC100291393          0.126   PREDICTED: hypothetical protein XP_002347924 
FER                   0.035   fer (fps/fes related) tyrosine kinase 
BCAR3                 0.031   breast cancer antiestrogen resistance 3 
SH2B2                 0.026   SH2B adaptor protein 2 
SH2D3A                0.026   SH2 domain containing 3A 
SH2B1                 0.025   SH2B adaptor protein 1 isoform 2 
VAV1                  0.025   vav 1 guanine nucleotide exchange factor 
SH2B1                 0.025   SH2B adaptor protein 1 isoform 3 
SH2B1                 0.025   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.025   SH2B adaptor protein 1 isoform 1 
SH2B1                 0.025   SH2B adaptor protein 1 isoform 2 
FRK                   0.024   fyn-related kinase 
SH2D3C                0.024   SH2 domain containing 3C isoform e 
SH2D3C                0.024   SH2 domain containing 3C isoform d 
SH2D3C                0.024   SH2 domain containing 3C isoform b 
SH2D3C                0.024   SH2 domain containing 3C isoform a 
PTPN11                0.023   protein tyrosine phosphatase, non-receptor type 11 [...
ANKS1B                0.023   cajalin 2 isoform b 
ANKS1B                0.023   cajalin 2 isoform a 
ANKS1B                0.023   cajalin 2 isoform c 
PIK3R3                0.022   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.022   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
FES                   0.021   feline sarcoma oncogene isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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