Guide to the Human Genome
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Name: SHC1 Sequence: fasta or formatted (473aa) NCBI GI: 194239668
Description:

SHC (Src homology 2 domain containing) transforming protein 1 isoform 4

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Other entries for this name:
alt prot [583aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
alt prot [584aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
alt prot [474aa] SHC (Src homology 2 domain containing) transforming protein 1 iso...
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.4         35           2
 C cysteine            1.7          8           1
 D aspartate           5.1         24           2
 E glutamate           6.1         29           5
 F phenylalanine       3.0         14           1
 G glycine             9.5         45           4
 H histidine           3.0         14           2
 I isoleucine          2.7         13           2
 K lysine              3.8         18           1
 L leucine             8.9         42           3
 M methionine          2.7         13           1
 N asparagine          3.6         17           1
 P proline             9.9         47           5
 Q glutamine           4.9         23           2
 R arginine            7.0         33           3
 S serine              6.3         30           2
 T threonine           4.4         21           3
 V valine              7.0         33           2
 W tryptophan          0.8          4           1
 Y tyrosine            2.1         10           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SHC (Src homology 2 domain containing) transforming... 
SHC1                  1.000   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.996   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.996   SHC (Src homology 2 domain containing) transforming ...
SHC3                  0.483   src homology 2 domain-containing transforming prote...
SHC2                  0.483   SHC (Src homology 2 domain containing) transforming...
SHC4                  0.425   rai-like protein 
LOC100291393          0.146   PREDICTED: hypothetical protein XP_002347924 
FER                   0.044   fer (fps/fes related) tyrosine kinase 
SH2D3A                0.041   SH2 domain containing 3A 
SH2B1                 0.040   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.040   SH2B adaptor protein 1 isoform 3 
SH2B1                 0.040   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.040   SH2B adaptor protein 1 isoform 1 
SH2B1                 0.040   SH2B adaptor protein 1 isoform 2 
GULP1                 0.038   GULP, engulfment adaptor PTB domain containing 1 [Hom...
FES                   0.037   feline sarcoma oncogene isoform 2 
FES                   0.037   feline sarcoma oncogene isoform 1 
SH2D3C                0.037   SH2 domain containing 3C isoform a 
BCAR3                 0.037   breast cancer antiestrogen resistance 3 
SH2B3                 0.036   SH2B adaptor protein 3 
SH2B2                 0.035   SH2B adaptor protein 2 
SH2D3C                0.034   SH2 domain containing 3C isoform b 
SH2D3C                0.034   SH2 domain containing 3C isoform e 
SH2D3C                0.034   SH2 domain containing 3C isoform d 
SHD                   0.033   Src homology 2 domain containing transforming prote...
PLCG2                 0.029   phospholipase C, gamma 2 
NCK1                  0.029   NCK adaptor protein 1 
ABL2                  0.029   arg tyrosine kinase isoform c 
ABL2                  0.029   arg tyrosine kinase isoform b 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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