Guide to the Human Genome
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Name: SHC2 Sequence: fasta or formatted (582aa) NCBI GI: 169790811
Description:

SHC (Src homology 2 domain containing) transforming protein 2

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            12.2         71           5
 C cysteine            2.1         12           2
 D aspartate           5.2         30           1
 E glutamate           5.8         34           2
 F phenylalanine       2.2         13           1
 G glycine             9.8         57           2
 H histidine           3.4         20           2
 I isoleucine          2.9         17           2
 K lysine              2.9         17           3
 L leucine             8.8         51           3
 M methionine          1.9         11           1
 N asparagine          1.9         11           1
 P proline            10.8         63           2
 Q glutamine           3.4         20           1
 R arginine            6.9         40           2
 S serine              6.9         40           1
 T threonine           3.8         22           2
 V valine              5.8         34           2
 W tryptophan          1.4          8           1
 Y tyrosine            1.9         11           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   SHC (Src homology 2 domain containing) transforming... 
SHC1                  0.407   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.407   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.390   SHC (Src homology 2 domain containing) transforming...
SHC1                  0.389   SHC (Src homology 2 domain containing) transforming ...
SHC3                  0.370   src homology 2 domain-containing transforming prote...
LOC100291393          0.345   PREDICTED: hypothetical protein XP_002347924 
SHC4                  0.296   rai-like protein 
FER                   0.040   fer (fps/fes related) tyrosine kinase 
BCAR3                 0.031   breast cancer antiestrogen resistance 3 
GULP1                 0.030   GULP, engulfment adaptor PTB domain containing 1 [Hom...
FES                   0.030   feline sarcoma oncogene isoform 2 
FES                   0.030   feline sarcoma oncogene isoform 1 
SH2B2                 0.029   SH2B adaptor protein 2 
SH2B1                 0.027   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.027   SH2B adaptor protein 1 isoform 3 
SH2B1                 0.027   SH2B adaptor protein 1 isoform 2 
SH2B1                 0.027   SH2B adaptor protein 1 isoform 1 
SH2B1                 0.027   SH2B adaptor protein 1 isoform 2 
SH2D3C                0.025   SH2 domain containing 3C isoform e 
SH2D3C                0.025   SH2 domain containing 3C isoform d 
SH2D3C                0.025   SH2 domain containing 3C isoform b 
SH2D3C                0.025   SH2 domain containing 3C isoform a 
SH2D3A                0.025   SH2 domain containing 3A 
GRB2                  0.022   growth factor receptor-bound protein 2 isoform 1 [Hom...
SH2B3                 0.022   SH2B adaptor protein 3 
ABL2                  0.021   arg tyrosine kinase isoform c 
ABL2                  0.021   arg tyrosine kinase isoform b 
ABL2                  0.021   arg tyrosine kinase isoform e 
ABL2                  0.021   arg tyrosine kinase isoform d 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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