Guide to the Human Genome
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Search of human proteins with 239749791

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]
         (671 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]         1373   0.0  
gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]         1369   0.0  
gi|126091152 cubilin [Homo sapiens]                                   457   e-128
gi|222537750 ankyrin repeat domain 30B [Homo sapiens]                 241   2e-63
gi|115495445 ankyrin repeat domain 30A [Homo sapiens]                 198   2e-50
gi|239757619 PREDICTED: similar to hCG1644292 [Homo sapiens]          186   5e-47
gi|239752110 PREDICTED: hypothetical protein XP_002348113 [Homo ...   186   5e-47
gi|239743843 PREDICTED: hypothetical protein XP_002342968 [Homo ...   171   2e-42
gi|239743812 PREDICTED: similar to hCG1644292 [Homo sapiens]          171   2e-42
gi|239758143 PREDICTED: similar to hCG1644292 [Homo sapiens]          165   1e-40
gi|22547221 tolloid-like 1 [Homo sapiens]                             102   1e-21
gi|6912724 tolloid-like 2 [Homo sapiens]                               97   6e-20
gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Hom...    94   5e-19
gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Hom...    86   9e-17
gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Hom...    86   9e-17
gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]       82   2e-15
gi|72384339 CUB domain containing protein 2 [Homo sapiens]             79   2e-14
gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]       73   1e-12
gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]       72   2e-12
gi|239756223 PREDICTED: ankyrin repeat domain-containing protein...    68   3e-11
gi|169209369 PREDICTED: similar to Putative ankyrin repeat domai...    68   3e-11
gi|239745040 PREDICTED: ankyrin repeat domain-containing protein...    68   3e-11
gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3 pre...    67   5e-11
gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2 pre...    67   5e-11
gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]      62   2e-09
gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]      62   2e-09
gi|148539844 deleted in malignant brain tumors 1 isoform c precu...    62   2e-09
gi|148539842 deleted in malignant brain tumors 1 isoform b precu...    62   2e-09
gi|148539840 deleted in malignant brain tumors 1 isoform a precu...    62   2e-09
gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]            61   4e-09

>gi|239749791 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 671

 Score = 1373 bits (3554), Expect = 0.0
 Identities = 671/671 (100%), Positives = 671/671 (100%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
           MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC
Sbjct: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60

Query: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
           ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT
Sbjct: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120

Query: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
           FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR
Sbjct: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180

Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
           PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP
Sbjct: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240

Query: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
           NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF
Sbjct: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300

Query: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
           ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR
Sbjct: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360

Query: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
           HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR
Sbjct: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420

Query: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
           TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA
Sbjct: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480

Query: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
           AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD
Sbjct: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540

Query: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
           EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT
Sbjct: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600

Query: 601 AKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
           AKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS
Sbjct: 601 AKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660

Query: 661 TKASTNGKMLE 671
           TKASTNGKMLE
Sbjct: 661 TKASTNGKMLE 671


>gi|239755296 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 671

 Score = 1369 bits (3544), Expect = 0.0
 Identities = 669/671 (99%), Positives = 670/671 (99%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
           MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC
Sbjct: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60

Query: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
           ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT
Sbjct: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120

Query: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
           FSNLRLA HLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR
Sbjct: 121 FSNLRLATHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180

Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240
           PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP
Sbjct: 181 PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNP 240

Query: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300
           NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF
Sbjct: 241 NQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLF 300

Query: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360
           ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR
Sbjct: 301 ADGTGLRELLKGGGHGRRLQVHRVLLEHWDDLLHLQSHSFQALGVVLLQDVQLRLGQVWR 360

Query: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420
           HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR
Sbjct: 361 HMASLVQGIHQAPRRSSMVMTELWLVQARMWSLPLQETECRAVWPLSAAQGSVPFSSSYR 420

Query: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480
           TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA
Sbjct: 421 TFSTSLALVALALSPSFSSELHLFARATTPGAALRHTATSRVVVQWGLGPGGLLAREAHA 480

Query: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540
           AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD
Sbjct: 481 AAPVQTRSQRRRRGPSLARLADSALNTNPRPYPIFLHCLPALSQSHATEQPEGTSEGTPD 540

Query: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600
           EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT
Sbjct: 541 EAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRT 600

Query: 601 AKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660
           AKETS+KFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS
Sbjct: 601 AKETSKKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETS 660

Query: 661 TKASTNGKMLE 671
           TKASTNGKMLE
Sbjct: 661 TKASTNGKMLE 671


>gi|126091152 cubilin [Homo sapiens]
          Length = 3623

 Score =  457 bits (1176), Expect = e-128
 Identities = 241/333 (72%), Positives = 248/333 (74%), Gaps = 69/333 (20%)

Query: 1    MYLRFRSDNSPNHMGFK----------------------------------------GLS 20
            MYLRFRSDNSP H+GFK                                        GLS
Sbjct: 2312 MYLRFRSDNSPTHVGFKAKYSIAQCGGRVPGQSGVVESIGHPTLPYRDNLFCEWHLQGLS 2371

Query: 21   RHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVR-V 79
             HYLT SFEDFNLQNSSGCEKDFVEIWD HTSGNILGRYC NTIPDS DTSSNTAVVR V
Sbjct: 2372 GHYLTISFEDFNLQNSSGCEKDFVEIWDNHTSGNILGRYCGNTIPDSIDTSSNTAVVRFV 2431

Query: 80   WWGS---------------------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
              GS                     QGS GT TSPNYPN NPHGRI EWRITAPEGR+IT
Sbjct: 2432 TDGSVTASGFRLRFESSMEECGGDLQGSIGTFTSPNYPNPNPHGRICEWRITAPEGRRIT 2491

Query: 119  LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
            L F+NLRLA H SCN+EHVIVFNGIRSNSPQLEKLCSSVNVS+EIKSSGNTMKVIFFTDG
Sbjct: 2492 LMFNNLRLATHPSCNNEHVIVFNGIRSNSPQLEKLCSSVNVSNEIKSSGNTMKVIFFTDG 2551

Query: 179  SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
            SRPYGGFTAS+TSSEDA       +CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS
Sbjct: 2552 SRPYGGFTASYTSSEDA-------VCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 2604

Query: 239  NPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRV 271
            NPNQGNSSI IHFEDFYLESHQDCQFDVLEFRV
Sbjct: 2605 NPNQGNSSISIHFEDFYLESHQDCQFDVLEFRV 2637



 Score = 91.3 bits (225), Expect = 3e-18
 Identities = 72/279 (25%), Positives = 120/279 (43%), Gaps = 39/279 (13%)

Query: 7    SDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPD 66
            S+N   +   +  + + +  +F  F+L++   C  D++E++D       +GRYC   +P 
Sbjct: 1301 SENQHCNWTIRATTGNTVNYTFLAFDLEHHINCSTDYLELYD---GPRQMGRYCGVDLPP 1357

Query: 67   STDTSSNTAVVRV---------------WW----GSQ--GSAGTSTSPNYPNLNPHGRIY 105
               T+S+   V +               W+    G +  G+ G+ +SP +PN  P  +  
Sbjct: 1358 PGSTTSSKLQVLLLTDGVGRREKGFQMQWFVYGCGGELSGATGSFSSPGFPNRYPPNKEC 1417

Query: 106  EWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCS--SVNVSSEI 163
             W I    G  I LT  +  +  H  CN + + ++ G   +SP++ +LC+  S     ++
Sbjct: 1418 IWYIRTDPGSSIQLTIHDFDVEYHSRCNFDVLEIYGGPDFHSPRIAQLCTQRSPENPMQV 1477

Query: 164  KSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDG 223
             S+GN + + F TD S    GF AS      A   GC     G +   P G   SP Y  
Sbjct: 1478 SSTGNELAIRFKTDLSINGRGFNASW----QAVTGGC-----GGIFQAPSGEIHSPNYPS 1528

Query: 224  VRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
               Y  N +C W +      N  + ++F DF LE    C
Sbjct: 1529 --PYRSNTDCSWVIRVDR--NHRVLLNFTDFDLEPQDSC 1563



 Score = 88.6 bits (218), Expect = 2e-17
 Identities = 76/271 (28%), Positives = 117/271 (43%), Gaps = 40/271 (14%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVWW 81
            H +   FE F+L+    C  D++E++D  +  + LGRYC  +IP S  +S N+ ++    
Sbjct: 968  HLIHLMFETFHLEFHYNCTNDYLEVYDTDSETS-LGRYCGKSIPPSLTSSGNSLMLVFVT 1026

Query: 82   GSQ------------------------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQI 117
             S                            GT TSPN+PN  P+     +RIT   G+ I
Sbjct: 1027 DSDLAYEGFLINYEAISAATACLQDYTDDLGTFTSPNFPNNYPNNWECIYRITVRTGQLI 1086

Query: 118  TLTFSNLRLAMHL-SCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
             + F+N  L   + +  ++ + + +G    SP L     S N+   I S  N + + F +
Sbjct: 1087 AVHFTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGS-NLPPTIISHSNKLWLKFKS 1145

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWT 236
            D      GF+A    S           CGG+L  T  G F SP Y     Y  +  C W 
Sbjct: 1146 DQIDTRSGFSAYWDGSSTG--------CGGNL-TTSSGTFISPNYP--MPYYHSSECYWW 1194

Query: 237  LSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
            L + +   S+  + F+DF+LE H +C  D L
Sbjct: 1195 LKSSH--GSAFELEFKDFHLEHHPNCTLDYL 1223



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 76/267 (28%), Positives = 115/267 (43%), Gaps = 35/267 (13%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCAN-----------------TIPDSTD 69
           +F    LQ  S   ++++E+ D  T   +LG+ C N                  I  S +
Sbjct: 749 NFTHVELQCQSDSSQNYIEVRDGET---LLGKVCGNGTISHIKSITNSVWIRFKIDASVE 805

Query: 70  TSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAM 128
            +S  AV +V  G + +  G   SP +PN+ P  R   W I  P+ + I L F+   +  
Sbjct: 806 KASFRAVYQVACGDELTGEGVIRSPFFPNVYPGERTCRWTIHQPQSQVILLNFTVFEIGS 865

Query: 129 HLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTAS 188
              C +++V + +     SP+ +K C + ++ S I S  N + V F    S    GF A 
Sbjct: 866 SAHCETDYVEIGSSSILGSPENKKYCGT-DIPSFITSVYNFLYVTFVKSSSTENHGFMAK 924

Query: 189 HTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIY 248
             S+ED        L  G +     G   SPG+  V  Y   +NC W +    Q N  I+
Sbjct: 925 F-SAED--------LACGEILTESTGTIQSPGHPNV--YPHGINCTWHIL--VQPNHLIH 971

Query: 249 IHFEDFYLESHQDCQFDVLEFRVVASE 275
           + FE F+LE H +C  D LE     SE
Sbjct: 972 LMFETFHLEFHYNCTNDYLEVYDTDSE 998



 Score = 84.0 bits (206), Expect = 4e-16
 Identities = 63/269 (23%), Positives = 115/269 (42%), Gaps = 32/269 (11%)

Query: 27   SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIP-------------------DS 67
            SF  F L++S  C +DFVEI + + +G+++GRYC N+ P                     
Sbjct: 1779 SFISFQLEDSQDCSRDFVEIREGNATGHLVGRYCGNSFPLNYSSIVGHTLWVRFISDGSG 1838

Query: 68   TDTSSNTAVVRVWWGSQ--GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLR 125
            + T      ++++      G+ G   SP +P   PH   Y+W +       +      + 
Sbjct: 1839 SGTGFQATFMKIFGNDNIVGTHGKVASPFWPENYPHNSNYQWTVNVNASHVVHGRILEMD 1898

Query: 126  LAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGF 185
            +    +C  + + +++G   ++  +   C +   S    S+GN++   F++D S    GF
Sbjct: 1899 IEEIQNCYYDKLRIYDGPSIHARLIGAYCGTQTES--FSSTGNSLTFHFYSDSSISGKGF 1956

Query: 186  TASHTSSEDADKV---GCCKLCGGSLPNTPEGNFT-SPGYDGVRNYSRNLNCEWTLSNPN 241
                 + +  D V        CGG L       F  SPG+    +YS  ++C W +  P 
Sbjct: 1957 LLEWFAVDAPDGVLPTIAPGACGGFLRTGDAPVFLFSPGWPD--SYSNRVDCTWLIQAP- 2013

Query: 242  QGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
              +S++ ++     +ESH+ C +D L  R
Sbjct: 2014 --DSTVELNILSLDIESHRTCAYDSLVIR 2040



 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 64/267 (23%), Positives = 113/267 (42%), Gaps = 35/267 (13%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWDYHTSGNI-LGRYCANTIPDSTDTSSNTAVVRVW----- 80
           +F  F L++   C  +F++++D  +S    LGR+C +++P    +S N     ++     
Sbjct: 515 TFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGSSLPHELLSSDNALYFHLYSEHLR 574

Query: 81  --------WGSQ---------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
                   W +Q         G  G+  SP YP   P GR   W +       +T TF  
Sbjct: 575 NGRGFTVRWETQQPECGGILTGPYGSIKSPGYPGNYPPGRDCVWIVVTSPDLLVTFTFGT 634

Query: 124 LRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
           L L  H  CN +++ + +G     P L K C++ +V   ++++G   ++ F +D      
Sbjct: 635 LSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSV-PPLQTTGPFARIHFHSDSQISDQ 693

Query: 184 GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
           GF  ++ +S    +      CGG+  + PEG    P   G   ++R   C + +  P   
Sbjct: 694 GFHITYLTSPSDLR------CGGNYTD-PEGELFLPELSGPFTHTR--QCVYMMKQPQ-- 742

Query: 244 NSSIYIHFEDFYLESHQDCQFDVLEFR 270
              I I+F    L+   D   + +E R
Sbjct: 743 GEQIQINFTHVELQCQSDSSQNYIEVR 769



 Score = 81.6 bits (200), Expect = 2e-15
 Identities = 69/258 (26%), Positives = 106/258 (41%), Gaps = 45/258 (17%)

Query: 27   SFEDFNLQNSSGCEKDFVEIWDYHTSGNILG-----RYCANTIPDSTDTSSNTAVVRVWW 81
            +F  F + +S+ CE D+VEI     S +ILG     +YC   IP    +  N   V    
Sbjct: 857  NFTVFEIGSSAHCETDYVEIG----SSSILGSPENKKYCGTDIPSFITSVYNFLYVTFVK 912

Query: 82   GSQG----------------------SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITL 119
             S                        S GT  SP +PN+ PHG    W I       I L
Sbjct: 913  SSSTENHGFMAKFSAEDLACGEILTESTGTIQSPGHPNVYPHGINCTWHILVQPNHLIHL 972

Query: 120  TFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGS 179
             F    L  H +C ++++ V++    +   L + C   ++   + SSGN++ ++F TD  
Sbjct: 973  MFETFHLEFHYNCTNDYLEVYD--TDSETSLGRYCGK-SIPPSLTSSGNSLMLVFVTDSD 1029

Query: 180  RPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
              Y GF  ++ +   A    C +     L     G FTSP +    NY  N  C + ++ 
Sbjct: 1030 LAYEGFLINYEAISAA--TACLQDYTDDL-----GTFTSPNFP--NNYPNNWECIYRIT- 1079

Query: 240  PNQGNSSIYIHFEDFYLE 257
              +    I +HF +F LE
Sbjct: 1080 -VRTGQLIAVHFTNFSLE 1096



 Score = 80.5 bits (197), Expect = 5e-15
 Identities = 71/249 (28%), Positives = 109/249 (43%), Gaps = 39/249 (15%)

Query: 9    NSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCAN---TIP 65
            ++PN  G   +S H     FEDF L++   C+ D +E       G ++ R C     T+P
Sbjct: 2604 SNPNQ-GNSSISIH-----FEDFYLESHQDCQFDVLEFRVGDADGPLMWRLCGPSKPTLP 2657

Query: 66   DSTDTS-------SNTAVVRVWWGSQ-----------GSAGTSTSPNYPNLNPHGRIYEW 107
                 S       +N  V  + + ++           G +G  TSPNYPN          
Sbjct: 2658 LVIPYSQVWIHFVTNERVEHIGFHAKYSFTDCGGIQIGDSGVITSPNYPNAYDSLTHCSS 2717

Query: 108  RITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSG 167
             + AP+G  ITLTFS+  +  H +C  + V V NG    SP + + C + N  + I+S  
Sbjct: 2718 LLEAPQGHTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRT-IQSGS 2776

Query: 168  NTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNY 227
            N + V F +D S   GGF A+     +   +GC     G + ++  G   SP +   +N+
Sbjct: 2777 NQLVVTFNSDHSLQGGGFYATW----NTQTLGC-----GGIFHSDNGTIRSPHWP--QNF 2825

Query: 228  SRNLNCEWT 236
              N  C WT
Sbjct: 2826 PENSRCSWT 2834



 Score = 79.0 bits (193), Expect = 1e-14
 Identities = 67/264 (25%), Positives = 114/264 (43%), Gaps = 43/264 (16%)

Query: 28   FEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVWW--GSQ 84
            F+DF+L++   C  D++ ++D  +S + +L + C +  P    +S ++  +++    G Q
Sbjct: 1207 FKDFHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGDEKPPLIRSSGDSMFIKLRTDEGQQ 1266

Query: 85   GSA-------------------GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLR 125
            G                     G   S  YPN     +   W I A  G  +  TF    
Sbjct: 1267 GRGFKAEYRQTCENVVIVNQTYGILESIGYPNPYSENQHCNWTIRATTGNTVNYTFLAFD 1326

Query: 126  LAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG-SRPYGG 184
            L  H++C+++++ +++G R    Q+ + C  V++     ++ + ++V+  TDG  R   G
Sbjct: 1327 LEHHINCSTDYLELYDGPR----QMGRYCG-VDLPPPGSTTSSKLQVLLLTDGVGRREKG 1381

Query: 185  FTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGN 244
            F                  CGG L     G+F+SPG+     Y  N  C W +       
Sbjct: 1382 FQMQWFVYG----------CGGELSGAT-GSFSSPGFPN--RYPPNKECIWYIRT--DPG 1426

Query: 245  SSIYIHFEDFYLESHQDCQFDVLE 268
            SSI +   DF +E H  C FDVLE
Sbjct: 1427 SSIQLTIHDFDVEYHSRCNFDVLE 1450



 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 56/187 (29%), Positives = 91/187 (48%), Gaps = 13/187 (6%)

Query: 86   SAGTSTSPNYPNLN-PHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIR 144
            S+G  TSP Y   + P+     + IT  + + I L FS+  +    SC+ +++ +++G  
Sbjct: 3044 SSGIITSPAYSYADYPNDMHCLYTITVSDDKVIELKFSDFDVVPSTSCSHDYLAIYDGAN 3103

Query: 145  SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
            ++ P L K C S      +KSS N+M ++F TD  +   G+  S   +     +G  + C
Sbjct: 3104 TSDPLLGKFCGSKR-PPNVKSSNNSMLLVFKTDSFQTAKGWKMSFRQT-----LGPQQGC 3157

Query: 205  GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLE---SHQD 261
            GG L  +    F SP  D    Y +NLNC W +  P   N  I++ F  F LE   + Q 
Sbjct: 3158 GGYLTGS-NNTFASPDSDSNGMYDKNLNCVWIIIAP--VNKVIHLTFNTFALEAASTRQR 3214

Query: 262  CQFDVLE 268
            C +D ++
Sbjct: 3215 CLYDYVK 3221



 Score = 77.8 bits (190), Expect = 3e-14
 Identities = 82/305 (26%), Positives = 125/305 (40%), Gaps = 39/305 (12%)

Query: 28   FEDFNLQNSSG-CEKDFVEIWDY-HTSGNILGRYCANTIPDSTDTSSNTAVVRV------ 79
            F +F+L+ + G    DF+EI D  +    +LG +  + +P +  + SN   ++       
Sbjct: 1090 FTNFSLEEAIGNYYTDFLEIRDGGYEKSPLLGIFYGSNLPPTIISHSNKLWLKFKSDQID 1149

Query: 80   --------WWGSQG--------SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
                    W GS          S+GT  SPNYP    H     W + +  G    L F +
Sbjct: 1150 TRSGFSAYWDGSSTGCGGNLTTSSGTFISPNYPMPYYHSSECYWWLKSSHGSAFELEFKD 1209

Query: 124  LRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
              L  H +C  +++ V++G  SNS  L +LC        I+SSG++M +   TD  +   
Sbjct: 1210 FHLEHHPNCTLDYLAVYDGPSSNSHLLTQLCGD-EKPPLIRSSGDSMFIKLRTDEGQQGR 1268

Query: 184  GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
            GF A +  +        C+     + N   G   S GY     YS N +C WT+     G
Sbjct: 1269 GFKAEYRQT--------CE--NVVIVNQTYGILESIGYP--NPYSENQHCNWTI-RATTG 1315

Query: 244  NSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSGWSECSLERNLFADG 303
            N+  Y  F  F LE H +C  D LE      +  +     +      +   L+  L  DG
Sbjct: 1316 NTVNYT-FLAFDLEHHINCSTDYLELYDGPRQMGRYCGVDLPPPGSTTSSKLQVLLLTDG 1374

Query: 304  TGLRE 308
             G RE
Sbjct: 1375 VGRRE 1379



 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 72/274 (26%), Positives = 115/274 (41%), Gaps = 49/274 (17%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDY-HTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
            +++T SF  F L+ S+ C +DFVEI D  H    + GRYC   +P    + S+   +R  
Sbjct: 1658 NHITLSFTHFELERSTTCARDFVEILDGGHEDAPLRGRYCGTDMPHPITSFSSALTLRFV 1717

Query: 81   WGSQGSAG----------------------TSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
              S  SAG                         SP YP++ P      W I +  G ++ 
Sbjct: 1718 SDSSISAGGFHTTVTASVSACGGTFYMAEGIFNSPGYPDIYPPNVECVWNIVSSPGNRLQ 1777

Query: 119  LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS---VNVSSEIKSSGNTMKVIFF 175
            L+F + +L     C+ + V +  G  +    + + C +   +N SS +   G+T+ V F 
Sbjct: 1778 LSFISFQLEDSQDCSRDFVEIREG-NATGHLVGRYCGNSFPLNYSSIV---GHTLWVRFI 1833

Query: 176  TDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 235
            +DGS    GF A+             K+ G        G   SP +    NY  N N +W
Sbjct: 1834 SDGSGSGTGFQATF-----------MKIFGNDNIVGTHGKVASPFWP--ENYPHNSNYQW 1880

Query: 236  TLSNPNQGNSSIYIH--FEDFYLESHQDCQFDVL 267
            T++     N+S  +H    +  +E  Q+C +D L
Sbjct: 1881 TVN----VNASHVVHGRILEMDIEEIQNCYYDKL 1910



 Score = 77.0 bits (188), Expect = 5e-14
 Identities = 62/186 (33%), Positives = 93/186 (50%), Gaps = 20/186 (10%)

Query: 86   SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLAMHLSCNSEHVIVFNGIR 144
            SAG  TSPN+P+  P      W + AP   +I L F +   + +  +C S ++ + +G+ 
Sbjct: 2228 SAGYVTSPNHPHNYPPHADCIWILAAPPETRIQLQFEDRFDIEVTPNCTSNYLELRDGVD 2287

Query: 145  SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
            S++P L K C +   SS+  SSG  M + F +D S  + GF A ++ ++          C
Sbjct: 2288 SDAPILSKFCGTSLPSSQ-WSSGEVMYLRFRSDNSPTHVGFKAKYSIAQ----------C 2336

Query: 205  GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIY--IHFEDFYLESHQDC 262
            GG +P    G   S G+  +  Y  NL CEW L    QG S  Y  I FEDF L++   C
Sbjct: 2337 GGRVPG-QSGVVESIGHPTL-PYRDNLFCEWHL----QGLSGHYLTISFEDFNLQNSSGC 2390

Query: 263  QFDVLE 268
            + D +E
Sbjct: 2391 EKDFVE 2396



 Score = 73.9 bits (180), Expect = 4e-13
 Identities = 53/175 (30%), Positives = 81/175 (46%), Gaps = 14/175 (8%)

Query: 88   GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNS 147
            G   SP +P+   + +     +TAP+   I+L F +L +   + C ++ + V NG  SNS
Sbjct: 3404 GNLRSPGWPDNYDNDKDCTVTLTAPQNHTISLFFHSLGIENSVECRNDFLEVRNGSNSNS 3463

Query: 148  PQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGS 207
            P L K C ++ + + + S  N + + F +D      G+    TSS           CGG+
Sbjct: 3464 PLLGKYCGTL-LPNPVFSQNNELYLRFKSDSVTSDRGYEIIWTSSPSG--------CGGT 3514

Query: 208  LPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
            L     G+FTSPGY G   Y  N  CEW L  P      + I+F    ++   DC
Sbjct: 3515 LYG-DRGSFTSPGYPG--TYPNNTYCEWVLVAP--AGRLVTINFYFISIDDPGDC 3564



 Score = 73.2 bits (178), Expect = 7e-13
 Identities = 45/187 (24%), Positives = 80/187 (42%), Gaps = 23/187 (12%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVR-- 78
            H ++  F    ++NS  C  DF+E+ +   S + +LG+YC   +P+   + +N   +R  
Sbjct: 3431 HTISLFFHSLGIENSVECRNDFLEVRNGSNSNSPLLGKYCGTLLPNPVFSQNNELYLRFK 3490

Query: 79   ------------VWWGSQ--------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
                        +W  S         G  G+ TSP YP   P+    EW + AP GR +T
Sbjct: 3491 SDSVTSDRGYEIIWTSSPSGCGGTLYGDRGSFTSPGYPGTYPNNTYCEWVLVAPAGRLVT 3550

Query: 119  LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
            + F  + +     C   ++ +++G  ++SP     C      +   +S N + + F  D 
Sbjct: 3551 INFYFISIDDPGDCVQNYLTLYDGPNASSPSSGPYCGGDTSIAPFVASSNQVFIKFHADY 3610

Query: 179  SRPYGGF 185
            +R    F
Sbjct: 3611 ARRPSAF 3617



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 65/270 (24%), Positives = 106/270 (39%), Gaps = 48/270 (17%)

Query: 27   SFEDFNLQNSSGCEKDFVEIW---DYHTSGNILGRYCANTIPDS---------------- 67
            +  DF+++  S C  D +EI+   D+H+    + + C    P++                
Sbjct: 1432 TIHDFDVEYHSRCNFDVLEIYGGPDFHSPR--IAQLCTQRSPENPMQVSSTGNELAIRFK 1489

Query: 68   TDTSSNTAVVRVWWGS---------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
            TD S N       W +         Q  +G   SPNYP+         W I      ++ 
Sbjct: 1490 TDLSINGRGFNASWQAVTGGCGGIFQAPSGEIHSPNYPSPYRSNTDCSWVIRVDRNHRVL 1549

Query: 119  LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
            L F++  L    SC    ++ ++G+ S   +L + C    +++ I SSGN++ + F +  
Sbjct: 1550 LNFTDFDLEPQDSC----IMAYDGLSSTMSRLARTCGREQLANPIVSSGNSLFLRFQSGP 1605

Query: 179  SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
            SR   GF A    +           CGG +  +     +SP +    NY  N NC W + 
Sbjct: 1606 SRQNRGFRAQFRQA-----------CGGHILTSSFDTVSSPRFPA--NYPNNQNCSWIIQ 1652

Query: 239  NPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
                 N  I + F  F LE    C  D +E
Sbjct: 1653 AQPPLN-HITLSFTHFELERSTTCARDFVE 1681



 Score = 65.9 bits (159), Expect = 1e-10
 Identities = 50/165 (30%), Positives = 77/165 (46%), Gaps = 16/165 (9%)

Query: 107 WRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSS 166
           W I    G+ + +TF+  RL    +C  E + V++G  S++ QL + C S ++  E+ SS
Sbjct: 502 WVIKTEMGKVLRITFTFFRLESMDNCPHEFLQVYDGDSSSAFQLGRFCGS-SLPHELLSS 560

Query: 167 GNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRN 226
            N +    +++  R   GFT    + +          CGG L   P G+  SPGY G  N
Sbjct: 561 DNALYFHLYSEHLRNGRGFTVRWETQQPE--------CGGILTG-PYGSIKSPGYPG--N 609

Query: 227 YSRNLNCEW-TLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
           Y    +C W  +++P   +  +   F    LE H DC  D LE R
Sbjct: 610 YPPGRDCVWIVVTSP---DLLVTFTFGTLSLEHHDDCNKDYLEIR 651



 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 66/264 (25%), Positives = 107/264 (40%), Gaps = 46/264 (17%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVR-- 78
            H +T +F DF+++  + C  D V + +  +  + I+G+YC N+ P +  + SN  VV   
Sbjct: 2725 HTITLTFSDFDIEPHTTCAWDSVTVRNGGSPESPIIGQYCGNSNPRTIQSGSNQLVVTFN 2784

Query: 79   -----------VWWGSQ---------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
                         W +Q            GT  SP++P   P      W     + + + 
Sbjct: 2785 SDHSLQGGGFYATWNTQTLGCGGIFHSDNGTIRSPHWPQNFPENSRCSWTAITHKSKHLE 2844

Query: 119  LTFSN--LRLAMHLSCNSEHVIVFNGIRS-NSPQLEKLCSSVNVSSEIKSSGNTMKVIFF 175
            ++F N  L  +    C +  V V+ G    +   L   C +V     I  S NT   +F 
Sbjct: 2845 ISFDNNFLIPSGDGQCQNSFVKVWAGTEEVDKALLATGCGNVAPGPVITPS-NTFTAVFQ 2903

Query: 176  TDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEW 235
            +    P  GF+AS  S            CG +    P G   SP Y   + Y  N+NC +
Sbjct: 2904 SQ-EAPAQGFSASFVSR-----------CGSNFTG-PSGYIISPNYP--KQYDNNMNCTY 2948

Query: 236  TL-SNPNQGNSSIYIHFEDFYLES 258
             + +NP    S + + F  F+LE+
Sbjct: 2949 VIEANP---LSVVLLTFVSFHLEA 2969



 Score = 61.2 bits (147), Expect = 3e-09
 Identities = 48/161 (29%), Positives = 72/161 (44%), Gaps = 18/161 (11%)

Query: 92   SPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLE 151
            SP +P+   +     W I AP+   + L   +L +  H +C  + +++ +G  + + QL 
Sbjct: 1993 SPGWPDSYSNRVDCTWLIQAPDST-VELNILSLDIESHRTCAYDSLVIRDGDNNLAQQLA 2051

Query: 152  KLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNT 211
             LC    +   I+S+G  M + F +D S    GF AS   S           CGG L + 
Sbjct: 2052 VLCGR-EIPGPIRSTGEYMFIRFTSDSSVTRAGFNASFHKS-----------CGGYL-HA 2098

Query: 212  PEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFE 252
              G  TSP Y     Y  NLNC W +    Q   +I +HFE
Sbjct: 2099 DRGIITSPKYP--ETYPSNLNCSWHVL--VQSGLTIAVHFE 2135



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 72/292 (24%), Positives = 119/292 (40%), Gaps = 48/292 (16%)

Query: 28   FEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPDSTDTSSNTAVV--------- 77
            F DF++  S+ C  D++ I+D  +TS  +LG++C +  P +  +S+N+ ++         
Sbjct: 3080 FSDFDVVPSTSCSHDYLAIYDGANTSDPLLGKFCGSKRPPNVKSSNNSMLLVFKTDSFQT 3139

Query: 78   -RVWWGS--------QGSAGTSTSPNYPNLNP---HGRIYE------WRITAPEGRQITL 119
             + W  S        QG  G  T  N    +P      +Y+      W I AP  + I L
Sbjct: 3140 AKGWKMSFRQTLGPQQGCGGYLTGSNNTFASPDSDSNGMYDKNLNCVWIIIAPVNKVIHL 3199

Query: 120  TFSNLRL---AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            TF+   L   +    C  ++V +++G   N+      C S  V +   SSGN + V F +
Sbjct: 3200 TFNTFALEAASTRQRCLYDYVKLYDGDSENANLAGTFCGS-TVPAPFISSGNFLTVQFIS 3258

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNT-PEGNFTSP-GYDGVRNYSRNLNCE 234
            D +    GF A++T  +          CGG+   T    N +SP   D    +S    C 
Sbjct: 3259 DLTLEREGFNATYTIMD--------MPCGGTYNATWTPQNISSPNSSDPDVPFS---ICT 3307

Query: 235  WTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISR 286
            W + +P      I +        + QDC  + L+ +     H    F    R
Sbjct: 3308 WVIDSPPHQQVKITVWALQL---TSQDCTQNYLQLQDSPQGHGNSRFQFCGR 3356



 Score = 59.7 bits (143), Expect = 9e-09
 Identities = 67/270 (24%), Positives = 107/270 (39%), Gaps = 47/270 (17%)

Query: 24  LTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVWWG 82
           +T +F   +L++   C KD++EI D     + +LG++C         T+   A +     
Sbjct: 628 VTFTFGTLSLEHHDDCNKDYLEIRDGPLYQDPLLGKFCTTFSVPPLQTTGPFARIHFHSD 687

Query: 83  SQGS-----------------AGTSTSPN----YPNLN---PHGRIYEWRITAPEGRQIT 118
           SQ S                  G  T P      P L+    H R   + +  P+G QI 
Sbjct: 688 SQISDQGFHITYLTSPSDLRCGGNYTDPEGELFLPELSGPFTHTRQCVYMMKQPQGEQIQ 747

Query: 119 LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
           + F++    + L C S+    +  +R     L K+C +  + S IKS  N++ + F  D 
Sbjct: 748 INFTH----VELQCQSDSSQNYIEVRDGETLLGKVCGNGTI-SHIKSITNSVWIRFKIDA 802

Query: 179 SRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLS 238
           S     F A +  +           CG  L  T EG   SP +  V  Y     C WT+ 
Sbjct: 803 SVEKASFRAVYQVA-----------CGDEL--TGEGVIRSPFFPNV--YPGERTCRWTIH 847

Query: 239 NPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
            P   +  I ++F  F + S   C+ D +E
Sbjct: 848 QPQ--SQVILLNFTVFEIGSSAHCETDYVE 875



 Score = 54.3 bits (129), Expect = 4e-07
 Identities = 56/196 (28%), Positives = 82/196 (41%), Gaps = 26/196 (13%)

Query: 88   GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMH--LSCN-SEHVIVFNGIR 144
            G  TSP YP   P      W +    G  I + F       +   SCN  +++++ NG  
Sbjct: 2101 GIITSPKYPETYPSNLNCSWHVLVQSGLTIAVHFEQPFQIPNGDSSCNQGDYLVLRNGPD 2160

Query: 145  SNSPQL------EKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKV 198
              SP L         C S + SS + +S N M V F +D S    GF   + +   A   
Sbjct: 2161 ICSPPLGPPGGNGHFCGS-HASSTLFTSDNQMFVQFISDHSNEGQGFKIKYEAKSLA--- 2216

Query: 199  GCCKLCGGSL---PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFED-F 254
                 CGG++        G  TSP +    NY  + +C W L+ P +  + I + FED F
Sbjct: 2217 -----CGGNVYIHDADSAGYVTSPNHP--HNYPPHADCIWILAAPPE--TRIQLQFEDRF 2267

Query: 255  YLESHQDCQFDVLEFR 270
             +E   +C  + LE R
Sbjct: 2268 DIEVTPNCTSNYLELR 2283



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 20/187 (10%)

Query: 88   GTSTSPNYPNLNPHGRIY--EWRITAPE--GRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
            G  TSP Y  +  + R    EW ++ P      I++ F +  L  H  C  + V+ F   
Sbjct: 2580 GNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSISIHFEDFYLESHQDCQFD-VLEFRVG 2638

Query: 144  RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
             ++ P + +LC     +  +    + + + F T+    + GF A ++ ++          
Sbjct: 2639 DADGPLMWRLCGPSKPTLPLVIPYSQVWIHFVTNERVEHIGFHAKYSFTD---------- 2688

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG +     G  TSP Y     Y    +C   L  P QG++ I + F DF +E H  C 
Sbjct: 2689 CGG-IQIGDSGVITSPNYPNA--YDSLTHCSSLLEAP-QGHT-ITLTFSDFDIEPHTTCA 2743

Query: 264  FDVLEFR 270
            +D +  R
Sbjct: 2744 WDSVTVR 2750


>gi|222537750 ankyrin repeat domain 30B [Homo sapiens]
          Length = 1392

 Score =  241 bits (614), Expect = 2e-63
 Identities = 119/145 (82%), Positives = 127/145 (87%)

Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVEGTADKIQCLGKA 581
           L ++     PEGTS GTPDEAAPLAERTPD AESL+EK PDEAA LVEGT+ KIQCLGKA
Sbjct: 264 LPKNPQNTNPEGTSTGTPDEAAPLAERTPDTAESLLEKTPDEAARLVEGTSAKIQCLGKA 323

Query: 582 TSGKFEQSAEETPKKIMRTAKETSEKFAWPAKERPRKITWEEKETSVKTECVAGVIPNKT 641
           TSGKFEQS EETP+KI+R  KETSEKF+WPAKER RKITWEEKETSVKTECVAGV PNKT
Sbjct: 324 TSGKFEQSTEETPRKILRPTKETSEKFSWPAKERSRKITWEEKETSVKTECVAGVTPNKT 383

Query: 642 EVLEKGTSEMLTCPTKETSTKASTN 666
           EVLEKGTS M+ CPTKETSTKASTN
Sbjct: 384 EVLEKGTSNMIACPTKETSTKASTN 408


>gi|115495445 ankyrin repeat domain 30A [Homo sapiens]
          Length = 1341

 Score =  198 bits (503), Expect = 2e-50
 Identities = 113/201 (56%), Positives = 123/201 (61%), Gaps = 56/201 (27%)

Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDEAAPLVE------------ 569
           LS++H    PEGTS GTPDEAAPLAERTPD AESLVEK PDEAAPLVE            
Sbjct: 208 LSKNHQNTNPEGTSAGTPDEAAPLAERTPDTAESLVEKTPDEAAPLVERTPDTAESLVEK 267

Query: 570 ----------GTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP-------- 611
                     GT+DKIQCL KATSGKFEQSAEETP++I   AKETSEKF WP        
Sbjct: 268 TPDEAASLVEGTSDKIQCLEKATSGKFEQSAEETPREITSPAKETSEKFTWPAKGRPRKI 327

Query: 612 --------------------------AKERPRKITWEEKETSVKTECVAGVIPNKTEVLE 645
                                     AK RPRKI WE+KET VKT CVA V  NKT+VLE
Sbjct: 328 AWEKKEDTPREIMSPAKETSEKFTWAAKGRPRKIAWEKKETPVKTGCVARVTSNKTKVLE 387

Query: 646 KGTSEMLTCPTKETSTKASTN 666
           KG S+M+ CPTKE+STKAS N
Sbjct: 388 KGRSKMIACPTKESSTKASAN 408


>gi|239757619 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 118

 Score =  186 bits (473), Expect = 5e-47
 Identities = 94/120 (78%), Positives = 105/120 (87%), Gaps = 2/120 (1%)

Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP 611
           MAESLVE+ PDEAAPLVEGT+D++QCLGK  SGK EQSA ETP+KI R  KETSEKFAWP
Sbjct: 1   MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKTEQSARETPRKITRPVKETSEKFAWP 60

Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTKASTNGKMLE 671
            +ERP K TWEEKETSVKTECVAGV  NK EVLE+GT++M+TCPTK T+TKASTNGKMLE
Sbjct: 61  -QERPTKTTWEEKETSVKTECVAGVTSNKIEVLEEGTAKMITCPTK-TATKASTNGKMLE 118


>gi|239752110 PREDICTED: hypothetical protein XP_002348113 [Homo
           sapiens]
          Length = 118

 Score =  186 bits (473), Expect = 5e-47
 Identities = 94/120 (78%), Positives = 105/120 (87%), Gaps = 2/120 (1%)

Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP 611
           MAESLVE+ PDEAAPLVEGT+D++QCLGK  SGK EQSA ETP+KI R  KETSEKFAWP
Sbjct: 1   MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKTEQSARETPRKITRPVKETSEKFAWP 60

Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTKASTNGKMLE 671
            +ERP K TWEEKETSVKTECVAGV  NK EVLE+GT++M+TCPTK T+TKASTNGKMLE
Sbjct: 61  -QERPTKTTWEEKETSVKTECVAGVTSNKIEVLEEGTAKMITCPTK-TATKASTNGKMLE 118


>gi|239743843 PREDICTED: hypothetical protein XP_002342968 [Homo
           sapiens]
          Length = 139

 Score =  171 bits (433), Expect = 2e-42
 Identities = 84/111 (75%), Positives = 95/111 (85%), Gaps = 1/111 (0%)

Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP 611
           MAESLVE+ PDEAAPLVEGT+D++QCLGK  SGK E+SA ETP+KI R  KETSEKFAWP
Sbjct: 1   MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60

Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
            +ERP K TWEEKETSVKTECVAGV  NKTEVLE+GTS+M+TCPTK+   K
Sbjct: 61  -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110


>gi|239743812 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 139

 Score =  171 bits (433), Expect = 2e-42
 Identities = 84/111 (75%), Positives = 95/111 (85%), Gaps = 1/111 (0%)

Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP 611
           MAESLVE+ PDEAAPLVEGT+D++QCLGK  SGK E+SA ETP+KI R  KETSEKFAWP
Sbjct: 1   MAESLVERTPDEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60

Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
            +ERP K TWEEKETSVKTECVAGV  NKTEVLE+GTS+M+TCPTK+   K
Sbjct: 61  -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110


>gi|239758143 PREDICTED: similar to hCG1644292 [Homo sapiens]
          Length = 115

 Score =  165 bits (418), Expect = 1e-40
 Identities = 82/111 (73%), Positives = 93/111 (83%), Gaps = 1/111 (0%)

Query: 552 MAESLVEKPPDEAAPLVEGTADKIQCLGKATSGKFEQSAEETPKKIMRTAKETSEKFAWP 611
           MAESLVE+   EAAPLVEGT+D++QCLGK  SGK E+SA ETP+KI R  KETSEKFAWP
Sbjct: 1   MAESLVERTQHEAAPLVEGTSDEVQCLGKTISGKIEESAGETPRKITRPVKETSEKFAWP 60

Query: 612 AKERPRKITWEEKETSVKTECVAGVIPNKTEVLEKGTSEMLTCPTKETSTK 662
            +ERP K TWEEKETSVKTECVAGV  NKTEVLE+GTS+M+TCPTK+   K
Sbjct: 61  -QERPTKTTWEEKETSVKTECVAGVTSNKTEVLEEGTSKMITCPTKKQLQK 110


>gi|22547221 tolloid-like 1 [Homo sapiens]
          Length = 1013

 Score =  102 bits (253), Expect = 1e-21
 Identities = 76/272 (27%), Positives = 123/272 (45%), Gaps = 33/272 (12%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRY- 59
           M + F+SDN+ +  GFK    H+ ++  +D   +++ GC+ + V         N +G Y 
Sbjct: 708 MRIEFKSDNTVSKKGFKA---HFFSD--KDECSKDNGGCQHECV---------NTMGSYM 753

Query: 60  --CANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQI 117
             C N      D   +             +G  TSPN+P+  P  +   W I+A  G +I
Sbjct: 754 CQCRNGFV-LHDNKHDCKEAECEQKIHSPSGLITSPNWPDKYPSRKECTWEISATPGHRI 812

Query: 118 TLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
            L FS   +  H  C  +H+ VF+G    SP L +LC +  +   + ++GN M V F +D
Sbjct: 813 KLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGN-KIPDPLVATGNKMFVRFVSD 871

Query: 178 GSRPYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWT 236
            S    GF A+H++            CGG L   +   +  S    G  NY   ++CEW 
Sbjct: 872 ASVQRKGFQATHSTE-----------CGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWL 920

Query: 237 LSNPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
           L   ++  S + + F+ F +E   DC +D +E
Sbjct: 921 L--VSERGSRLELSFQTFEVEEEADCGYDYVE 950



 Score =  101 bits (252), Expect = 2e-21
 Identities = 82/293 (27%), Positives = 129/293 (44%), Gaps = 56/293 (19%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSN- 73
           +F   +L  SS C  D++E+ D Y     +LGR+C + +P+   STD+        SSN 
Sbjct: 390 NFTTMDLYKSSLCWYDYIEVRDGYWRKSPLLGRFCGDKLPEVLTSTDSRMWIEFRSSSNW 449

Query: 74  -----TAVVRVWWGSQ--GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
                 AV     G +   + G   SPNYP+     +   W+IT  E   + LTF +  +
Sbjct: 450 VGKGFAAVYEAICGGEIRKNEGQIQSPNYPDDYRPMKECVWKITVSESYHVGLTFQSFEI 509

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
             H +C  +++ V +G   NSP + + C   +   +I+S+ NT+ + F +DG+    GF 
Sbjct: 510 ERHDNCAYDYLEVRDGTSENSPLIGRFCG-YDKPEDIRSTSNTLWMKFVSDGTVNKAGFA 568

Query: 187 ASHTSSED----ADKVGC---------------------------CKLCGGSLPNTPEGN 215
           A+    ED     D+ GC                           C+   G L     G 
Sbjct: 569 ANFFKEEDECAKPDRGGCEQRCLNTLGSYQCACEPGYELGPDRRSCEAACGGLLTKLNGT 628

Query: 216 FTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
            T+PG+   + Y  N NC W +  P Q    I + FE F LE ++ C++D +E
Sbjct: 629 ITTPGWP--KEYPPNKNCVWQVVAPTQ--YRISVKFEFFELEGNEVCKYDYVE 677



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 61/233 (26%), Positives = 95/233 (40%), Gaps = 40/233 (17%)

Query: 88  GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNS 147
           GT T+P +P   P  +   W++ AP   +I++ F    L  +  C  ++V +++G+ S S
Sbjct: 627 GTITTPGWPKEYPPNKNCVWQVVAPTQYRISVKFEFFELEGNEVCKYDYVEIWSGLSSES 686

Query: 148 PQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSED---ADKVGCCKLC 204
               K C +  V   I S  N M++ F +D +    GF A   S +D    D  GC   C
Sbjct: 687 KLHGKFCGA-EVPEVITSQFNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHEC 745

Query: 205 GGSLP----------------------------NTPEGNFTSPGYDGVRNYSRNLNCEWT 236
             ++                             ++P G  TSP +     Y     C W 
Sbjct: 746 VNTMGSYMCQCRNGFVLHDNKHDCKEAECEQKIHSPSGLITSPNWPD--KYPSRKECTWE 803

Query: 237 LSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFRVVASEHWKVPFSLISRLSG 289
           +S        I + F +F +E HQ+C +D LE  V   E  K P  ++ RL G
Sbjct: 804 IS--ATPGHRIKLAFSEFEIEQHQECAYDHLE--VFDGETEKSP--ILGRLCG 850



 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 54/209 (25%), Positives = 90/209 (43%), Gaps = 21/209 (10%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           Q S G  +SP +PN  P      WR++   G +I L F+ + L     C  +++ V +G 
Sbjct: 354 QESNGNLSSPGFPNGYPSYTHCIWRVSVTPGEKIVLNFTTMDLYKSSLCWYDYIEVRDGY 413

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
              SP L + C    +   + S+ + M + F +  +    GF A + +           +
Sbjct: 414 WRKSPLLGRFCGD-KLPEVLTSTDSRMWIEFRSSSNWVGKGFAAVYEA-----------I 461

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG +    EG   SP Y    +Y     C W ++     +  + + F+ F +E H +C 
Sbjct: 462 CGGEIRKN-EGQIQSPNYPD--DYRPMKECVWKITVSE--SYHVGLTFQSFEIERHDNCA 516

Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
           +D LE R   SE+      LI R  G+ +
Sbjct: 517 YDYLEVRDGTSEN----SPLIGRFCGYDK 541



 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 48/194 (24%), Positives = 83/194 (42%), Gaps = 25/194 (12%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGN-ILGRYCANTIPDSTDTSSNTAVVRVW 80
            H +  +F +F ++    C  D +E++D  T  + ILGR C N IPD    + N   VR  
Sbjct: 810  HRIKLAFSEFEIEQHQECAYDHLEVFDGETEKSPILGRLCGNKIPDPLVATGNKMFVRFV 869

Query: 81   W-------GSQGSAGTS---------------TSPNYPNLNPHGRI-YEWRITAPEGRQI 117
                    G Q +  T                +   + + N  G++  EW + +  G ++
Sbjct: 870  SDASVQRKGFQATHSTECGGRLKAESKPRDLYSHAQFGDNNYPGQVDCEWLLVSERGSRL 929

Query: 118  TLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
             L+F    +     C  ++V +F+G+ S +  L + C S     EI S G+++ + F TD
Sbjct: 930  ELSFQTFEVEEEADCGYDYVELFDGLDSTAVGLGRFCGS-GPPEEIYSIGDSVLIHFHTD 988

Query: 178  GSRPYGGFTASHTS 191
             +    GF   + S
Sbjct: 989  DTINKKGFHIRYKS 1002


>gi|6912724 tolloid-like 2 [Homo sapiens]
          Length = 1015

 Score = 96.7 bits (239), Expect = 6e-20
 Identities = 84/296 (28%), Positives = 124/296 (41%), Gaps = 58/296 (19%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT-------SSNTA 75
           +F   +L  S  C  D+VE+ D Y     +LGR+C + IP+   STD+       SS+  
Sbjct: 392 NFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPLVSTDSRLWVEFRSSSNI 451

Query: 76  VVRVWWGSQGS---------AGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
           + + ++ +  +         AG   SPNYP+     +   WRIT  EG  + LTF    +
Sbjct: 452 LGKGFFAAYEATCGGDMNKDAGQIQSPNYPDDYRPSKECVWRITVSEGFHVGLTFQAFEI 511

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
             H SC  +++ V +G    S  +   C       ++KSS N + + F +DGS    GF 
Sbjct: 512 ERHDSCAYDYLEVRDGPTEESALIGHFC-GYEKPEDVKSSSNRLWMKFVSDGSINKAGFA 570

Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
           A+     D                                ADK  C   CGG +     G
Sbjct: 571 ANFFKEVDECSWPDHGGCEHRCVNTLGSYKCACDPGYELAADKKMCEVACGGFITKL-NG 629

Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
             TSPG+   + Y  N NC W +  P Q    I + FE F LE +  C++D +E R
Sbjct: 630 TITSPGWP--KEYPTNKNCVWQVVAPAQ--YRISLQFEVFELEGNDVCKYDFVEVR 681



 Score = 88.2 bits (217), Expect = 2e-17
 Identities = 65/269 (24%), Positives = 116/269 (43%), Gaps = 27/269 (10%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
           M + F+SDN+ +  GF+    H+ ++  +D   +++ GC+ + V  +  +      G + 
Sbjct: 710 MRVEFKSDNTVSKRGFRA---HFFSD--KDECAKDNGGCQHECVNTFGSYLCRCRNGYWL 764

Query: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
                D  +      +  V        GT  SPN+P+  P  R   W I++  G ++ LT
Sbjct: 765 HENGHDCKEAGCAHKISSV-------EGTLASPNWPDKYPSRRECTWNISSTAGHRVKLT 817

Query: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
           F+   +  H  C  +H+ +++G  S +P L + C S      + +SG++M + F++D S 
Sbjct: 818 FNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTV-ASGSSMFLRFYSDASV 876

Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
              GF A H++            CGG L          S    G  NY     C+W +  
Sbjct: 877 QRKGFQAVHSTE-----------CGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVI-- 923

Query: 240 PNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
             +    + + F  F +E   DC +D +E
Sbjct: 924 VAEDGYGVELTFRTFEVEEEADCGYDYME 952



 Score = 70.1 bits (170), Expect = 6e-12
 Identities = 73/301 (24%), Positives = 115/301 (38%), Gaps = 52/301 (17%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
           ++++F SD S N  GF            ++ +  +  GCE         H   N LG Y 
Sbjct: 554 LWMKFVSDGSINKAGFAA----NFFKEVDECSWPDHGGCE---------HRCVNTLGSYK 600

Query: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSA--GTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
               P   + +++  +  V  G   +   GT TSP +P   P  +   W++ AP   +I+
Sbjct: 601 CACDP-GYELAADKKMCEVACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRIS 659

Query: 119 LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
           L F    L  +  C  + V V +G+  ++    + C S      I S  N M+V F +D 
Sbjct: 660 LQFEVFELEGNDVCKYDFVEVRSGLSPDAKLHGRFCGS-ETPEVITSQSNNMRVEFKSDN 718

Query: 179 SRPYGGFTASHTSSED---ADKVGC---------------------------CKLCG-GS 207
           +    GF A   S +D    D  GC                           CK  G   
Sbjct: 719 TVSKRGFRAHFFSDKDECAKDNGGCQHECVNTFGSYLCRCRNGYWLHENGHDCKEAGCAH 778

Query: 208 LPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
             ++ EG   SP +     Y     C W +S  +     + + F +F +E HQ+C +D L
Sbjct: 779 KISSVEGTLASPNWPD--KYPSRRECTWNIS--STAGHRVKLTFNEFEIEQHQECAYDHL 834

Query: 268 E 268
           E
Sbjct: 835 E 835



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 25/199 (12%)

Query: 22   HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCANTIPDSTDTSSNTAVVRVW 80
            H +  +F +F ++    C  D +E++D   S   ILGR+C +  PD T  S ++  +R +
Sbjct: 812  HRVKLTFNEFEIEQHQECAYDHLEMYDGPDSLAPILGRFCGSKKPDPTVASGSSMFLRFY 871

Query: 81   -----------------WGSQGSAGTSTSPNYP------NLNPHGRIYEWRITAPEGRQI 117
                              G +  A   T   Y       N  P     +W I A +G  +
Sbjct: 872  SDASVQRKGFQAVHSTECGGRLKAEVQTKELYSHAQFGDNNYPSEARCDWVIVAEDGYGV 931

Query: 118  TLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
             LTF    +     C  +++  ++G  S++P+L + C S     EI S+G+++ + F TD
Sbjct: 932  ELTFRTFEVEEEADCGYDYMEAYDGYDSSAPRLGRFCGS-GPLEEIYSAGDSLMIRFRTD 990

Query: 178  GSRPYGGFTASHTSSEDAD 196
             +    GF A +TS++  D
Sbjct: 991  DTINKKGFHARYTSTKFQD 1009



 Score = 63.5 bits (153), Expect = 6e-10
 Identities = 47/187 (25%), Positives = 82/187 (43%), Gaps = 17/187 (9%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           Q + G  ++P +PN  P      WRI+   G +I L F+++ L     C  ++V V +G 
Sbjct: 356 QDTTGNFSAPGFPNGYPSYSHCVWRISVTPGEKIVLNFTSMDLFKSRLCWYDYVEVRDGY 415

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
              +P L + C    +   + S+ + + V F +  +    GF A++ ++           
Sbjct: 416 WRKAPLLGRFCGD-KIPEPLVSTDSRLWVEFRSSSNILGKGFFAAYEAT----------- 463

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG + N   G   SP Y    +Y  +  C W ++        + + F+ F +E H  C 
Sbjct: 464 CGGDM-NKDAGQIQSPNYPD--DYRPSKECVWRITVSE--GFHVGLTFQAFEIERHDSCA 518

Query: 264 FDVLEFR 270
           +D LE R
Sbjct: 519 YDYLEVR 525


>gi|5453579 bone morphogenetic protein 1 isoform 3 precursor [Homo
           sapiens]
          Length = 986

 Score = 93.6 bits (231), Expect = 5e-19
 Identities = 67/269 (24%), Positives = 123/269 (45%), Gaps = 27/269 (10%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYC 60
           M + F+SDN+ +  GFK    H+ ++  +D   +++ GC++D V  +  +      G   
Sbjct: 681 MRVEFKSDNTVSKKGFKA---HFFSD--KDECSKDNGGCQQDCVNTFGSYECQCRSGFVL 735

Query: 61  ANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLT 120
            +   D  +   +  V         ++GT TSPN+P+  P  +   W I++  G ++ LT
Sbjct: 736 HDNKHDCKEAGCDHKVT-------STSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLT 788

Query: 121 FSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSR 180
           F  + +     C  +H+ VF+G  + +P L + C S      + ++G+ M + F++D S 
Sbjct: 789 FMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGS-KKPEPVLATGSRMFLRFYSDNSV 847

Query: 181 PYGGFTASHTSSEDADKVGCCKLCGGSL-PNTPEGNFTSPGYDGVRNYSRNLNCEWTLSN 239
              GF ASH +            CGG +  +    +  S    G  NY   ++CEW +  
Sbjct: 848 QRKGFQASHATE-----------CGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVI-- 894

Query: 240 PNQGNSSIYIHFEDFYLESHQDCQFDVLE 268
             +    + + F+ F +E   DC +D +E
Sbjct: 895 VAEEGYGVELVFQTFEVEEETDCGYDYME 923



 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
           +F   +L  S  C  D+VE+ D +     + GR+C + +P+   STD+        SSN 
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422

Query: 75  ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
                 AV     G   +   G   SPNYP+     ++  WRI   EG  + LTF +  +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
             H SC  +++ V +G   +S  + + C       +IKS+ + + + F +DGS    GF 
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541

Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
            +     D                                 DK  C   CGG L     G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600

Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
           + TSPG+   + Y  N NC W L  P Q    I + F+ F  E +  C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652



 Score = 62.4 bits (150), Expect = 1e-09
 Identities = 47/199 (23%), Positives = 86/199 (43%), Gaps = 25/199 (12%)

Query: 22  HYLTNSFEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCANTIPDSTDTSSNTAVVRVW 80
           H +  +F + ++++   C  D +E++D   +   +LGR+C +  P+    + +   +R +
Sbjct: 783 HRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFY 842

Query: 81  -----------------WGSQGSAGTSTSPNYP------NLNPHGRIYEWRITAPEGRQI 117
                             G Q  A   T   Y       N  P G   EW I A EG  +
Sbjct: 843 SDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGV 902

Query: 118 TLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTD 177
            L F    +     C  +++ +F+G  S +P+L + C S     E+ S+G+++ V F +D
Sbjct: 903 ELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGS-GPPEEVYSAGDSVLVKFHSD 961

Query: 178 GSRPYGGFTASHTSSEDAD 196
            +    GF   +TS++  D
Sbjct: 962 DTITKKGFHLRYTSTKFQD 980



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           Q S G  +SP YPN         WRI+   G +I L F++L L     C  ++V V +G 
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
              +P   + C S  +   I S+ + + V F +  +    GF A + +           +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG +     G+  SP Y    +Y  +  C W +         + + F+ F +E H  C 
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489

Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
           +D LE R   SE      +LI R  G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514



 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 73/303 (24%), Positives = 109/303 (35%), Gaps = 56/303 (18%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
           ++L+F SD S N  GF         N F++ +     N  GCE+  +         N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568

Query: 58  RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            Y  +  P                G      G+ TSP +P   P  +   W++ AP   +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628

Query: 117 ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
           I+L F       +  C  + V V +G+ ++S    K C S      I S  N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687

Query: 177 DGSRPYGGFTASHTSSED---ADKVGC---------------------------CKLCG- 205
           D +    GF A   S +D    D  GC                           CK  G 
Sbjct: 688 DNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGC 747

Query: 206 GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFD 265
                +  G  TSP +     Y     C W +S  +     + + F +  +ES  +C +D
Sbjct: 748 DHKVTSTSGTITSPNWPD--KYPSKKECTWAIS--STPGHRVKLTFMEMDIESQPECAYD 803

Query: 266 VLE 268
            LE
Sbjct: 804 HLE 806


>gi|4502421 bone morphogenetic protein 1 isoform 1 precursor [Homo
           sapiens]
          Length = 730

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
           +F   +L  S  C  D+VE+ D +     + GR+C + +P+   STD+        SSN 
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422

Query: 75  ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
                 AV     G   +   G   SPNYP+     ++  WRI   EG  + LTF +  +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
             H SC  +++ V +G   +S  + + C       +IKS+ + + + F +DGS    GF 
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541

Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
            +     D                                 DK  C   CGG L     G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600

Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
           + TSPG+   + Y  N NC W L  P Q    I + F+ F  E +  C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           Q S G  +SP YPN         WRI+   G +I L F++L L     C  ++V V +G 
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
              +P   + C S  +   I S+ + + V F +  +    GF A + +           +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG +     G+  SP Y    +Y  +  C W +         + + F+ F +E H  C 
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489

Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
           +D LE R   SE      +LI R  G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514



 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 53/197 (26%), Positives = 78/197 (39%), Gaps = 22/197 (11%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
           ++L+F SD S N  GF         N F++ +     N  GCE+  +         N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568

Query: 58  RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            Y  +  P                G      G+ TSP +P   P  +   W++ AP   +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628

Query: 117 ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
           I+L F       +  C  + V V +G+ ++S    K C S      I S  N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687

Query: 177 DGSRPYGGFTASHTSSE 193
           D +    GF A H  SE
Sbjct: 688 DNTVSKKGFKA-HFFSE 703


>gi|5902808 bone morphogenetic protein 1 isoform 2 precursor [Homo
           sapiens]
          Length = 823

 Score = 86.3 bits (212), Expect = 9e-17
 Identities = 80/296 (27%), Positives = 121/296 (40%), Gaps = 58/296 (19%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPD---STDT--------SSNT 74
           +F   +L  S  C  D+VE+ D +     + GR+C + +P+   STD+        SSN 
Sbjct: 363 NFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNW 422

Query: 75  ------AVVRVWWGS--QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL 126
                 AV     G   +   G   SPNYP+     ++  WRI   EG  + LTF +  +
Sbjct: 423 VGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEI 482

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
             H SC  +++ V +G   +S  + + C       +IKS+ + + + F +DGS    GF 
Sbjct: 483 ERHDSCAYDYLEVRDGHSESSTLIGRYC-GYEKPDDIKSTSSRLWLKFVSDGSINKAGFA 541

Query: 187 ASHTSSED--------------------------------ADKVGCCKLCGGSLPNTPEG 214
            +     D                                 DK  C   CGG L     G
Sbjct: 542 VNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKL-NG 600

Query: 215 NFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVLEFR 270
           + TSPG+   + Y  N NC W L  P Q    I + F+ F  E +  C++D +E R
Sbjct: 601 SITSPGWP--KEYPPNKNCIWQLVAPTQ--YRISLQFDFFETEGNDVCKYDFVEVR 652



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 56/209 (26%), Positives = 88/209 (42%), Gaps = 21/209 (10%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           Q S G  +SP YPN         WRI+   G +I L F++L L     C  ++V V +G 
Sbjct: 327 QDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGF 386

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
              +P   + C S  +   I S+ + + V F +  +    GF A + +           +
Sbjct: 387 WRKAPLRGRFCGS-KLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEA-----------I 434

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG +     G+  SP Y    +Y  +  C W +         + + F+ F +E H  C 
Sbjct: 435 CGGDVKKD-YGHIQSPNYPD--DYRPSKVCIWRIQVSE--GFHVGLTFQSFEIERHDSCA 489

Query: 264 FDVLEFRVVASEHWKVPFSLISRLSGWSE 292
           +D LE R   SE      +LI R  G+ +
Sbjct: 490 YDYLEVRDGHSE----SSTLIGRYCGYEK 514



 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 50/191 (26%), Positives = 75/191 (39%), Gaps = 21/191 (10%)

Query: 1   MYLRFRSDNSPNHMGFKGLSRHYLTNSFEDFN---LQNSSGCEKDFVEIWDYHTSGNILG 57
           ++L+F SD S N  GF         N F++ +     N  GCE+  +         N LG
Sbjct: 525 LWLKFVSDGSINKAGFA-------VNFFKEVDECSRPNRGGCEQRCL---------NTLG 568

Query: 58  RYCANTIPDSTDTSSNTAVVRVWWGSQGSA-GTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            Y  +  P                G      G+ TSP +P   P  +   W++ AP   +
Sbjct: 569 SYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR 628

Query: 117 ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
           I+L F       +  C  + V V +G+ ++S    K C S      I S  N M+V F +
Sbjct: 629 ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGS-EKPEVITSQYNNMRVEFKS 687

Query: 177 DGSRPYGGFTA 187
           D +    GF A
Sbjct: 688 DNTVSKKGFKA 698


>gi|7019483 procollagen C-endopeptidase enhancer 2 [Homo sapiens]
          Length = 415

 Score = 82.0 bits (201), Expect = 2e-15
 Identities = 53/181 (29%), Positives = 88/181 (48%), Gaps = 8/181 (4%)

Query: 85  GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIR 144
           G +G   S  +P + P      W+IT PEG+ + L F  + L     C  + V V+NG  
Sbjct: 39  GESGFIGSEGFPGVYPPNSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNG-H 97

Query: 145 SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLC 204
           +N  ++ + C +    + + SSGN M V   +D +    GF A  +++E  ++    + C
Sbjct: 98  ANGQRIGRFCGTFRPGA-LVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGD--QYC 154

Query: 205 GGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQF 264
           GG L + P G+F +P +   R+Y   + C W +  P   N  I + FE F +E    C++
Sbjct: 155 GGLL-DRPSGSFKTPNWPD-RDYPAGVTCVWHIVAPK--NQLIELKFEKFDVERDNYCRY 210

Query: 265 D 265
           D
Sbjct: 211 D 211



 Score = 58.9 bits (141), Expect = 1e-08
 Identities = 45/189 (23%), Positives = 83/189 (43%), Gaps = 31/189 (16%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQGS 86
           +F   +L++ + C  DFV++++ H +G  +GR+C    P +  +S N  +V++   +  +
Sbjct: 74  NFRFIDLESDNLCRYDFVDVYNGHANGQRIGRFCGTFRPGALVSSGNKMMVQMISDANTA 133

Query: 87  ----------------------------AGTSTSPNYPNLN-PHGRIYEWRITAPEGRQI 117
                                       +G+  +PN+P+ + P G    W I AP+ + I
Sbjct: 134 GNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRDYPAGVTCVWHIVAPKNQLI 193

Query: 118 TLTFSNLRLAMHLSCNSEHVIVFNGIRSN-SPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            L F    +     C  ++V VFNG   N + ++ K C   +  + I S  N + + F +
Sbjct: 194 ELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGD-SPPAPIVSERNELLIQFLS 252

Query: 177 DGSRPYGGF 185
           D S    GF
Sbjct: 253 DLSLTADGF 261


>gi|72384339 CUB domain containing protein 2 [Homo sapiens]
          Length = 449

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 52/180 (28%), Positives = 81/180 (45%), Gaps = 17/180 (9%)

Query: 87  AGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSN 146
           +G  +SPN+P L P+     W I   EG  + LTF    L  H +C+ + + ++NG   +
Sbjct: 38  SGNFSSPNFPRLYPYNTECSWLIVVAEGSSVLLTFHAFDLEYHDTCSFDFLEIYNGASPD 97

Query: 147 SPQ-LEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCG 205
               L + C  V       SS + M VIF +D      GF+A +             +CG
Sbjct: 98  KGNLLGRFCGKV-PPPPFTSSWHVMSVIFHSDKHVASHGFSAGYQKD----------VCG 146

Query: 206 GSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFD 265
           G L     G  TSP Y    NY  ++ C W +     G + + + F DF +E +++C +D
Sbjct: 147 GVLTGL-SGVLTSPEYP--NNYPNSMECHWVIR--AAGPAHVKLVFVDFQVEGNEECTYD 201



 Score = 72.4 bits (176), Expect = 1e-12
 Identities = 72/276 (26%), Positives = 114/276 (41%), Gaps = 46/276 (16%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWDYHT--SGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQ 84
           +F  F+L+    C  DF+EI++  +   GN+LGR+C   +P    TSS   +  ++   +
Sbjct: 71  TFHAFDLEYHDTCSFDFLEIYNGASPDKGNLLGRFCGK-VPPPPFTSSWHVMSVIFHSDK 129

Query: 85  ---------------------GSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN 123
                                G +G  TSP YPN  P+     W I A     + L F +
Sbjct: 130 HVASHGFSAGYQKDVCGGVLTGLSGVLTSPEYPNNYPNSMECHWVIRAAGPAHVKLVFVD 189

Query: 124 LRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYG 183
            ++  +  C  ++V V  G      +    C S    + + S G+ ++V+F +D +    
Sbjct: 190 FQVEGNEECTYDYVAVLGG--PGPTRGHHYCGSTRPPT-LVSLGHELQVVFKSDFNIGGR 246

Query: 184 GFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQG 243
           GF A + S E       C+     +     GNF+SP Y    +Y  N+ C WT+  P   
Sbjct: 247 GFKAYYFSGE-------CQ----EVYMAMRGNFSSPQYPS--SYPNNIRCHWTIRLP--P 291

Query: 244 NSSIYIHFEDFYLES----HQDCQFDVLEFRVVASE 275
              + + F D  LE      + C FD L     ASE
Sbjct: 292 GYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASE 327



 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 54/242 (22%), Positives = 96/242 (39%), Gaps = 43/242 (17%)

Query: 8   DNSPN----HMGFKGLSRHYLTNSFEDFNLQNSSGCEKDFVEIWDYH--TSGNILGRYCA 61
           +N PN    H   +     ++   F DF ++ +  C  D+V +      T G+    YC 
Sbjct: 163 NNYPNSMECHWVIRAAGPAHVKLVFVDFQVEGNEECTYDYVAVLGGPGPTRGH---HYCG 219

Query: 62  NTIPDS-------------TDTSSNTAVVRVWWGS-------QGSAGTSTSPNYPNLNPH 101
           +T P +             +D +      + ++ S           G  +SP YP+  P+
Sbjct: 220 STRPPTLVSLGHELQVVFKSDFNIGGRGFKAYYFSGECQEVYMAMRGNFSSPQYPSSYPN 279

Query: 102 GRIYEWRITAPEGRQITLTFSNLRL----AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSV 157
                W I  P G Q+ + F +L L    ++  +C+ +H+  F+G    +P L   C   
Sbjct: 280 NIRCHWTIRLPPGYQVKVFFLDLDLEEPNSLTKTCDFDHLAAFDGASEEAPLLGNWCGH- 338

Query: 158 NVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFT 217
           ++   + SS N + ++  TD S    GF+ ++   +    +GC     GS     EG   
Sbjct: 339 HLPPPVTSSHNQLLLLLHTDRSTTRRGFSVAYIGGQ----LGC-----GSGSTEGEGEAL 389

Query: 218 SP 219
            P
Sbjct: 390 QP 391



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 27/65 (41%), Positives = 33/65 (50%), Gaps = 5/65 (7%)

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG L + P GNF+SP +   R Y  N  C W +       SS+ + F  F LE H  C 
Sbjct: 30  CGGVL-SAPSGNFSSPNFP--RLYPYNTECSWLIVVAE--GSSVLLTFHAFDLEYHDTCS 84

Query: 264 FDVLE 268
           FD LE
Sbjct: 85  FDFLE 89


>gi|157653329 procollagen C-endopeptidase enhancer [Homo sapiens]
          Length = 449

 Score = 72.8 bits (177), Expect = 1e-12
 Identities = 58/194 (29%), Positives = 82/194 (42%), Gaps = 32/194 (16%)

Query: 27  SFEDFNLQNSSGCEKDFVEIW-DYHTSGNILGRYCANTIPDSTDTSSNTAVVRV------ 79
           SF  F+L+    C  D +E++    TSG  LGR+C    P       N   +R+      
Sbjct: 78  SFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPLVAPGNQVTLRMTTDEGT 137

Query: 80  -------WWGSQGSAGTS---------------TSPNYPNLN-PHGRIYEWRITAPEGRQ 116
                  W+  + ++GT                T+PN+P  + P G    W I AP  + 
Sbjct: 138 GGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDYPPGISCSWHIIAPPDQV 197

Query: 117 ITLTFSNLRLAMHLSCNSEHVIVFNG-IRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFF 175
           I LTF    L     C  + V VFNG +  +S +L K C    V   I S GN + V F 
Sbjct: 198 IALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDA-VPGSISSEGNELLVQFV 256

Query: 176 TDGSRPYGGFTASH 189
           +D S    GF+AS+
Sbjct: 257 SDLSVTADGFSASY 270



 Score = 70.9 bits (172), Expect = 4e-12
 Identities = 48/182 (26%), Positives = 85/182 (46%), Gaps = 7/182 (3%)

Query: 84  QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGI 143
           +G +G   S  +PNL P  +   W IT PEG+ ++L+F    L +H +C  + + VF G 
Sbjct: 42  KGESGYVASEGFPNLYPPNKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGS 101

Query: 144 RSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVGCCKL 203
            ++  +L + C +    + + + GN + +   TD      GF   ++    +      + 
Sbjct: 102 GTSGQRLGRFCGTFR-PAPLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEH--QF 158

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG L    +G  T+P +    +Y   ++C W +  P   +  I + FE F LE    C+
Sbjct: 159 CGGRLEKA-QGTLTTPNWP-ESDYPPGISCSWHIIAP--PDQVIALTFEKFDLEPDTYCR 214

Query: 264 FD 265
           +D
Sbjct: 215 YD 216



 Score = 38.1 bits (87), Expect = 0.027
 Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 5/66 (7%)

Query: 203 LCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDC 262
           LCGG +     G   S G+  +  Y  N  C WT++ P     ++ + F  F LE H  C
Sbjct: 36  LCGGDVKGE-SGYVASEGFPNL--YPPNKECIWTITVPE--GQTVSLSFRVFDLELHPAC 90

Query: 263 QFDVLE 268
           ++D LE
Sbjct: 91  RYDALE 96


>gi|30520377 CUB and zona pellucida-like domains 1 [Homo sapiens]
          Length = 607

 Score = 72.0 bits (175), Expect = 2e-12
 Identities = 51/167 (30%), Positives = 83/167 (49%), Gaps = 20/167 (11%)

Query: 107 WRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSS 166
           W I  PE + I + FS ++L    SC SE++ VF+G  SN P L ++CS  +     +SS
Sbjct: 60  WTIERPENKSIRIIFSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESS 119

Query: 167 GNTMKVIFFTDGSR------PYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPG 220
            +T+     TD +R       +  F + + S  +         CGG L +T EG+FTSP 
Sbjct: 120 SSTLTFQIVTDSARIQRTVFVFYYFFSPNISIPN---------CGGYL-DTLEGSFTSPN 169

Query: 221 YDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQFDVL 267
           Y   + +     C W +    + +  I ++F++ +LE  + C+FD L
Sbjct: 170 YP--KPHPELAYCVWHIQ--VEKDYKIKLNFKEIFLEIDKQCKFDFL 212



 Score = 65.5 bits (158), Expect = 2e-10
 Identities = 49/193 (25%), Positives = 85/193 (44%), Gaps = 31/193 (16%)

Query: 28  FEDFNLQNSSGCEKDFVEIWDYHTS-GNILGRYCA-NTIPDSTDTSSNTAVVRVWWGS-- 83
           F    L     CE + ++++D  +S G +LG+ C+ N      ++SS+T   ++   S  
Sbjct: 74  FSYVQLDPDGSCESENIKVFDGTSSNGPLLGQVCSKNDYVPVFESSSSTLTFQIVTDSAR 133

Query: 84  -------------------------QGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQIT 118
                                        G+ TSPNYP  +P      W I   +  +I 
Sbjct: 134 IQRTVFVFYYFFSPNISIPNCGGYLDTLEGSFTSPNYPKPHPELAYCVWHIQVEKDYKIK 193

Query: 119 LTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDG 178
           L F  + L +   C  + + +++G  +NS  + ++C  V  + E  SS N++ V+  TD 
Sbjct: 194 LNFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFE--SSSNSLTVVLSTDY 251

Query: 179 SRPYGGFTASHTS 191
           +  Y GF+AS+TS
Sbjct: 252 ANSYRGFSASYTS 264



 Score = 30.0 bits (66), Expect = 7.2
 Identities = 45/175 (25%), Positives = 73/175 (41%), Gaps = 29/175 (16%)

Query: 27  SFEDFNLQNSSGCEKDFVEIWD-YHTSGNILGRYCANTIPDSTDTSSNTAVVRVWWGSQG 85
           +F++  L+    C+ DF+ I+D   T+  ++G+ C    P    +S++  VV     +  
Sbjct: 195 NFKEIFLEIDKQCKFDFLAIYDGPSTNSGLIGQVCGRVTPTFESSSNSLTVVLSTDYANS 254

Query: 86  SAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRS 145
             G S S        +  IY   I        +LT S+ R+ + +S    ++  FN    
Sbjct: 255 YRGFSAS--------YTSIYAENINT-----TSLTCSSDRMRVIIS--KSYLEAFNS-NG 298

Query: 146 NSPQLE------KLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGG---FTASHTS 191
           N+ QL+      KL + V  S  +   G   KV    D S  Y     F+AS TS
Sbjct: 299 NNLQLKDPTCRPKLSNVVEFSVPLNGCGTIRKV---EDQSITYTNIITFSASSTS 350


>gi|239756223 PREDICTED: ankyrin repeat domain-containing protein
           ENSP00000383090-like [Homo sapiens]
          Length = 270

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/42 (73%), Positives = 35/42 (83%)

Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
           +S++     PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 229 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270


>gi|169209369 PREDICTED: similar to Putative ankyrin repeat
           domain-containing protein ENSP00000383090 [Homo sapiens]
          Length = 193

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/42 (73%), Positives = 35/42 (83%)

Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
           +S++     PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 152 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 193


>gi|239745040 PREDICTED: ankyrin repeat domain-containing protein
           ENSP00000383090-like [Homo sapiens]
          Length = 270

 Score = 67.8 bits (164), Expect = 3e-11
 Identities = 31/42 (73%), Positives = 35/42 (83%)

Query: 522 LSQSHATEQPEGTSEGTPDEAAPLAERTPDMAESLVEKPPDE 563
           +S++     PEGTSEGTPDEAAPL ERTPDMAESLVE+ PDE
Sbjct: 229 ISKNSQNSNPEGTSEGTPDEAAPLVERTPDMAESLVERTPDE 270


>gi|20373181 neuropilin- and tolloid-like protein 1 isoform 3
           precursor [Homo sapiens]
          Length = 533

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 20/195 (10%)

Query: 81  WGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLAMHLSCNSEHVIV 139
           W      G  TSPNYP+  P  R   + I A   + I L F     +     C  +H+ V
Sbjct: 44  WTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEV 103

Query: 140 FNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVG 199
            +G    SP + + C   N    IKSSG  + + FF DG     GF+A +  + D D   
Sbjct: 104 RDGPFGFSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD 162

Query: 200 CCKLCGGSLPNTPEGNFTSPGYDGV-----------RNYSRNLNCEWTLSNPNQGNSSIY 248
                 G+L   P   F   G +G+              S  ++C+W +  P +  S IY
Sbjct: 163 L-----GALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPR--SKIY 215

Query: 249 IHFEDFYLESHQDCQ 263
           + F D+ +++  +C+
Sbjct: 216 LRFLDYEMQNSNECK 230



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 15/53 (28%), Positives = 30/53 (56%)

Query: 28  FEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
           F D+ +QNS+ C+++FV ++D  +S   L     +T+ +     +   V+R+W
Sbjct: 218 FLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMW 270



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 172 VIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNL 231
           +I    G+   G  T   T+SE    V C    G    +   G FTSP Y     Y  + 
Sbjct: 15  IILHLSGATKKG--TEKQTTSETQKSVQC----GTWTKHAEGGIFTSPNYPS--KYPPDR 66

Query: 232 NCEWTL-SNPNQGNSSIYIHFEDFY-LESHQDCQFDVLEFR 270
            C + + + P Q    I ++F++ Y +E   +C+FD +E R
Sbjct: 67  ECIYIIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVR 104


>gi|23510396 neuropilin- and tolloid-like protein 1 isoform 2
           precursor [Homo sapiens]
          Length = 532

 Score = 67.0 bits (162), Expect = 5e-11
 Identities = 53/195 (27%), Positives = 82/195 (42%), Gaps = 20/195 (10%)

Query: 81  WGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSN-LRLAMHLSCNSEHVIV 139
           W      G  TSPNYP+  P  R   + I A   + I L F     +     C  +H+ V
Sbjct: 43  WTKHAEGGIFTSPNYPSKYPPDRECIYIIEAAPRQCIELYFDEKYSIEPSWECKFDHIEV 102

Query: 140 FNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTSSEDADKVG 199
            +G    SP + + C   N    IKSSG  + + FF DG     GF+A +  + D D   
Sbjct: 103 RDGPFGFSPIIGRFCGQQN-PPVIKSSGRFLWIKFFADGELESMGFSARYNFTPDPDFKD 161

Query: 200 CCKLCGGSLPNTPEGNFTSPGYDGV-----------RNYSRNLNCEWTLSNPNQGNSSIY 248
                 G+L   P   F   G +G+              S  ++C+W +  P +  S IY
Sbjct: 162 L-----GALKPLPACEFEMGGSEGIVESIQIMKEGKATASEAVDCKWYIRAPPR--SKIY 214

Query: 249 IHFEDFYLESHQDCQ 263
           + F D+ +++  +C+
Sbjct: 215 LRFLDYEMQNSNECK 229



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 15/53 (28%), Positives = 30/53 (56%)

Query: 28  FEDFNLQNSSGCEKDFVEIWDYHTSGNILGRYCANTIPDSTDTSSNTAVVRVW 80
           F D+ +QNS+ C+++FV ++D  +S   L     +T+ +     +   V+R+W
Sbjct: 217 FLDYEMQNSNECKRNFVAVYDGSSSVEDLKAKFCSTVANDVMLRTGLGVIRMW 269



 Score = 30.4 bits (67), Expect = 5.5
 Identities = 29/101 (28%), Positives = 45/101 (44%), Gaps = 13/101 (12%)

Query: 172 VIFFTDGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPNTPEGNFTSPGYDGVRNYSRNL 231
           +I    G+   G  T   T+SE    V C    G    +   G FTSP Y     Y  + 
Sbjct: 14  IILHLSGATKKG--TEKQTTSETQKSVQC----GTWTKHAEGGIFTSPNYPS--KYPPDR 65

Query: 232 NCEWTL-SNPNQGNSSIYIHFEDFY-LESHQDCQFDVLEFR 270
            C + + + P Q    I ++F++ Y +E   +C+FD +E R
Sbjct: 66  ECIYIIEAAPRQ---CIELYFDEKYSIEPSWECKFDHIEVR 103


>gi|239755390 PREDICTED: similar to DMBT1 isoform 1 [Homo sapiens]
          Length = 1662

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 47   WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
            W  H  G+    G  C+ T  +ST T     + T   R      G    ++GT +SP+YP
Sbjct: 973  WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1032

Query: 97   NLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
               P+     W I    G +I L FSNL+L  H +C+ ++V +F+G  ++S  L K+C+ 
Sbjct: 1033 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1091

Query: 157  VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
             +      SS N M + F +D S    GF A + S
Sbjct: 1092 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1125



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 57   GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            G + +   P    T  NT      + SQ S G  +SP YP   P+     W I      +
Sbjct: 1236 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1294

Query: 117  ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            +T+ F +++L     CN +++ VF+G   +SP + ++C     S    SS N M + F +
Sbjct: 1295 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1350

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
            D S    GF A + SS   D      LC   LPN
Sbjct: 1351 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1379



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L + P G+F+SP Y G  NY  N  C W +    Q N  + + F D  LE    C 
Sbjct: 1257 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1309

Query: 264  FDVLE 268
            +D +E
Sbjct: 1310 YDYIE 1314



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L     G F+SP Y     Y  N  C W +   N G   I + F +  LE+H +C 
Sbjct: 1015 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1069

Query: 264  FDVLE 268
            FD +E
Sbjct: 1070 FDYVE 1074


>gi|239755388 PREDICTED: similar to DMBT1 isoform 2 [Homo sapiens]
          Length = 1788

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 47   WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
            W  H  G+    G  C+ T  +ST T     + T   R      G    ++GT +SP+YP
Sbjct: 1099 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1158

Query: 97   NLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
               P+     W I    G +I L FSNL+L  H +C+ ++V +F+G  ++S  L K+C+ 
Sbjct: 1159 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1217

Query: 157  VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
             +      SS N M + F +D S    GF A + S
Sbjct: 1218 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1251



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 57   GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            G + +   P    T  NT      + SQ S G  +SP YP   P+     W I      +
Sbjct: 1362 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1420

Query: 117  ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            +T+ F +++L     CN +++ VF+G   +SP + ++C     S    SS N M + F +
Sbjct: 1421 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1476

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
            D S    GF A + SS   D      LC   LPN
Sbjct: 1477 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1505



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L + P G+F+SP Y G  NY  N  C W +    Q N  + + F D  LE    C 
Sbjct: 1383 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1435

Query: 264  FDVLE 268
            +D +E
Sbjct: 1436 YDYIE 1440



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L     G F+SP Y     Y  N  C W +   N G   I + F +  LE+H +C 
Sbjct: 1141 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1195

Query: 264  FDVLE 268
            FD +E
Sbjct: 1196 FDYVE 1200


>gi|148539844 deleted in malignant brain tumors 1 isoform c precursor
            [Homo sapiens]
          Length = 2403

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 47   WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
            W  H  G+    G  C+ T  +ST T     + T   R      G    ++GT +SP+YP
Sbjct: 1714 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1773

Query: 97   NLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
               P+     W I    G +I L FSNL+L  H +C+ ++V +F+G  ++S  L K+C+ 
Sbjct: 1774 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1832

Query: 157  VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
             +      SS N M + F +D S    GF A + S
Sbjct: 1833 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1866



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 57   GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            G + +   P    T  NT      + SQ S G  +SP YP   P+     W I      +
Sbjct: 1977 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 2035

Query: 117  ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            +T+ F +++L     CN +++ VF+G   +SP + ++C     S    SS N M + F +
Sbjct: 2036 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 2091

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
            D S    GF A + SS   D      LC   LPN
Sbjct: 2092 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 2120



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L + P G+F+SP Y G  NY  N  C W +    Q N  + + F D  LE    C 
Sbjct: 1998 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 2050

Query: 264  FDVLE 268
            +D +E
Sbjct: 2051 YDYIE 2055



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L     G F+SP Y     Y  N  C W +   N G   I + F +  LE+H +C 
Sbjct: 1756 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1810

Query: 264  FDVLE 268
            FD +E
Sbjct: 1811 FDYVE 1815


>gi|148539842 deleted in malignant brain tumors 1 isoform b precursor
            [Homo sapiens]
          Length = 2413

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 47   WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
            W  H  G+    G  C+ T  +ST T     + T   R      G    ++GT +SP+YP
Sbjct: 1724 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1783

Query: 97   NLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
               P+     W I    G +I L FSNL+L  H +C+ ++V +F+G  ++S  L K+C+ 
Sbjct: 1784 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1842

Query: 157  VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
             +      SS N M + F +D S    GF A + S
Sbjct: 1843 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1876



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 57   GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            G + +   P    T  NT      + SQ S G  +SP YP   P+     W I      +
Sbjct: 1987 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 2045

Query: 117  ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            +T+ F +++L     CN +++ VF+G   +SP + ++C     S    SS N M + F +
Sbjct: 2046 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 2101

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
            D S    GF A + SS   D      LC   LPN
Sbjct: 2102 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 2130



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L + P G+F+SP Y G  NY  N  C W +    Q N  + + F D  LE    C 
Sbjct: 2008 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 2060

Query: 264  FDVLE 268
            +D +E
Sbjct: 2061 YDYIE 2065



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L     G F+SP Y     Y  N  C W +   N G   I + F +  LE+H +C 
Sbjct: 1766 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1820

Query: 264  FDVLE 268
            FD +E
Sbjct: 1821 FDYVE 1825


>gi|148539840 deleted in malignant brain tumors 1 isoform a precursor
            [Homo sapiens]
          Length = 1785

 Score = 62.0 bits (149), Expect = 2e-09
 Identities = 49/155 (31%), Positives = 74/155 (47%), Gaps = 12/155 (7%)

Query: 47   WDYHTSGNI--LGRYCANTIPDSTDTS----SNTAVVRVWWGSQG----SAGTSTSPNYP 96
            W  H  G+    G  C+ T  +ST T     + T   R      G    ++GT +SP+YP
Sbjct: 1096 WLTHNCGHHEDAGVICSATQINSTTTDWWHPTTTTTARPSSNCGGFLFYASGTFSSPSYP 1155

Query: 97   NLNPHGRIYEWRITAPEGRQITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSS 156
               P+     W I    G +I L FSNL+L  H +C+ ++V +F+G  ++S  L K+C+ 
Sbjct: 1156 AYYPNNAKCVWEIEVNSGYRINLGFSNLKLEAHHNCSFDYVEIFDGSLNSSLLLGKICN- 1214

Query: 157  VNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASHTS 191
             +      SS N M + F +D S    GF A + S
Sbjct: 1215 -DTRQIFTSSYNRMTIHFRSDISFQNTGFLAWYNS 1248



 Score = 53.1 bits (126), Expect = 8e-07
 Identities = 46/154 (29%), Positives = 68/154 (44%), Gaps = 10/154 (6%)

Query: 57   GRYCANTIPDSTDTSSNTAVVRVWWGSQGSAGTSTSPNYPNLNPHGRIYEWRITAPEGRQ 116
            G + +   P    T  NT      + SQ S G  +SP YP   P+     W I      +
Sbjct: 1359 GNHLSTPAPFLNITRPNTDYSCGGFLSQPS-GDFSSPFYPGNYPNNAKCVWDIEVQNNYR 1417

Query: 117  ITLTFSNLRLAMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFT 176
            +T+ F +++L     CN +++ VF+G   +SP + ++C     S    SS N M + F +
Sbjct: 1418 VTVIFRDVQLEG--GCNYDYIEVFDGPYRSSPLIARVCDGARGS--FTSSSNFMSIRFIS 1473

Query: 177  DGSRPYGGFTASHTSSEDADKVGCCKLCGGSLPN 210
            D S    GF A + SS   D      LC   LPN
Sbjct: 1474 DHSITRRGFRAEYYSSPSNDSTNL--LC---LPN 1502



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 25/65 (38%), Positives = 33/65 (50%), Gaps = 7/65 (10%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L + P G+F+SP Y G  NY  N  C W +    Q N  + + F D  LE    C 
Sbjct: 1380 CGGFL-SQPSGDFSSPFYPG--NYPNNAKCVWDIE--VQNNYRVTVIFRDVQLEG--GCN 1432

Query: 264  FDVLE 268
            +D +E
Sbjct: 1433 YDYIE 1437



 Score = 37.7 bits (86), Expect = 0.035
 Identities = 24/65 (36%), Positives = 31/65 (47%), Gaps = 5/65 (7%)

Query: 204  CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
            CGG L     G F+SP Y     Y  N  C W +   N G   I + F +  LE+H +C 
Sbjct: 1138 CGGFLFYA-SGTFSSPSYPAY--YPNNAKCVWEIE-VNSGYR-INLGFSNLKLEAHHNCS 1192

Query: 264  FDVLE 268
            FD +E
Sbjct: 1193 FDYVE 1197


>gi|41872572 neuropilin 2 isoform 3 precursor [Homo sapiens]
          Length = 909

 Score = 60.8 bits (146), Expect = 4e-09
 Identities = 58/195 (29%), Positives = 87/195 (44%), Gaps = 30/195 (15%)

Query: 87  AGTSTSPNYPNLNPHGRIYEWRITAPEGRQ-ITLTFS-NLRLAMHLSCNSEHVIVFNGIR 144
           AG  TSP YP   P  +  EW + APE  Q I L F+ +  +  H  C  + + + +G  
Sbjct: 37  AGYITSPGYPQDYPSHQNCEWIVYAPEPNQKIVLNFNPHFEIEKH-DCKYDFIEIRDGDS 95

Query: 145 SNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFTASH----TSSEDADKVGC 200
            ++  L K C ++     I SSG+ + + F +D +R   GF+  +    T SED  K   
Sbjct: 96  ESADLLGKHCGNI-APPTIISSGSMLYIKFTSDYARQGAGFSLRYEIFKTGSEDCSKNF- 153

Query: 201 CKLCGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWT-LSNPNQGNSSIYIHFEDFYLE-- 257
                     +P G   SPG+     Y  NL+C +T L+ P      I + F  F LE  
Sbjct: 154 ---------TSPNGTIESPGFP--EKYPHNLDCTFTILAKPKM---EIILQFLIFDLEHD 199

Query: 258 ----SHQDCQFDVLE 268
                  DC++D L+
Sbjct: 200 PLQVGEGDCKYDWLD 214



 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 3/72 (4%)

Query: 204 CGGSLPNTPEGNFTSPGYDGVRNYSRNLNCEWTLSNPNQGNSSIYIHFEDFYLESHQDCQ 263
           CGG L +   G  TSPGY   ++Y  + NCEW +  P + N  I ++F   +     DC+
Sbjct: 28  CGGRLNSKDAGYITSPGYP--QDYPSHQNCEWIVYAP-EPNQKIVLNFNPHFEIEKHDCK 84

Query: 264 FDVLEFRVVASE 275
           +D +E R   SE
Sbjct: 85  YDFIEIRDGDSE 96



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 44/183 (24%), Positives = 75/183 (40%), Gaps = 33/183 (18%)

Query: 39  CEKDFVEIWDYHT-SGNILGRYCANTIPDSTDTSSNTAVVRVW--WGSQGSA-------- 87
           C+ DF+EI D  + S ++LG++C N  P +  +S +   ++    +  QG+         
Sbjct: 83  CKYDFIEIRDGDSESADLLGKHCGNIAPPTIISSGSMLYIKFTSDYARQGAGFSLRYEIF 142

Query: 88  ---------------GTSTSPNYPNLNPHGRIYEWRITAPEGRQITLTFSNLRL------ 126
                          GT  SP +P   PH     + I A    +I L F    L      
Sbjct: 143 KTGSEDCSKNFTSPNGTIESPGFPEKYPHNLDCTFTILAKPKMEIILQFLIFDLEHDPLQ 202

Query: 127 AMHLSCNSEHVIVFNGIRSNSPQLEKLCSSVNVSSEIKSSGNTMKVIFFTDGSRPYGGFT 186
                C  + + +++GI    P + K C +    SE++SS   + + F TD +    GF+
Sbjct: 203 VGEGDCKYDWLDIWDGIPHVGPLIGKYCGT-KTPSELRSSTGILSLTFHTDMAVAKDGFS 261

Query: 187 ASH 189
           A +
Sbjct: 262 ARY 264


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.130    0.397 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,027,088
Number of Sequences: 37866
Number of extensions: 1367546
Number of successful extensions: 4933
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 70
Number of HSP's successfully gapped in prelim test: 68
Number of HSP's that attempted gapping in prelim test: 4265
Number of HSP's gapped (non-prelim): 500
length of query: 671
length of database: 18,247,518
effective HSP length: 109
effective length of query: 562
effective length of database: 14,120,124
effective search space: 7935509688
effective search space used: 7935509688
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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