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Search of human proteins with 11761629
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11761629 fibrinogen, alpha polypeptide isoform alpha
preproprotein [Homo sapiens]
(644 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11761629 fibrinogen, alpha polypeptide isoform alpha prepropr... 1322 0.0
gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E preprop... 1295 0.0
gi|57864582 hornerin [Homo sapiens] 72 2e-12
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 67 4e-11
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 67 4e-11
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 66 9e-11
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 66 9e-11
gi|195972866 keratin 10 [Homo sapiens] 66 1e-10
gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo ... 63 1e-09
gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo ... 63 1e-09
gi|62122917 filaggrin family member 2 [Homo sapiens] 61 3e-09
gi|167736355 mucin 4 isoform a [Homo sapiens] 59 1e-08
gi|60097902 filaggrin [Homo sapiens] 59 2e-08
gi|55956899 keratin 9 [Homo sapiens] 58 2e-08
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 58 2e-08
gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens] 57 4e-08
gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo ... 57 4e-08
gi|67782356 corneodesmosin precursor [Homo sapiens] 57 5e-08
gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo ... 57 7e-08
gi|47132620 keratin 2 [Homo sapiens] 56 9e-08
gi|161016767 mucin 21 [Homo sapiens] 56 1e-07
gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens] 56 1e-07
gi|119395750 keratin 1 [Homo sapiens] 54 3e-07
gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma... 53 1e-06
gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens] 52 1e-06
gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens] 52 1e-06
gi|239744589 PREDICTED: mucin 19 [Homo sapiens] 52 1e-06
gi|4504733 insulin receptor substrate 4 [Homo sapiens] 49 1e-05
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 49 1e-05
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 49 1e-05
>gi|11761629 fibrinogen, alpha polypeptide isoform alpha
preproprotein [Homo sapiens]
Length = 644
Score = 1322 bits (3422), Expect = 0.0
Identities = 644/644 (100%), Positives = 644/644 (100%)
Query: 1 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 60
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW
Sbjct: 1 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 60
Query: 61 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 120
NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA
Sbjct: 61 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 120
Query: 121 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 180
NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC
Sbjct: 121 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 180
Query: 181 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 240
RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ
Sbjct: 181 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 240
Query: 241 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 300
LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS
Sbjct: 241 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 300
Query: 301 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 360
GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW
Sbjct: 301 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 360
Query: 361 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 420
NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV
Sbjct: 361 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 420
Query: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
Query: 481 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 540
EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF
Sbjct: 481 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 540
Query: 541 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS
Sbjct: 541 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
Query: 601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPSLSP 644
YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPSLSP
Sbjct: 601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPSLSP 644
>gi|4503689 fibrinogen, alpha polypeptide isoform alpha-E
preproprotein [Homo sapiens]
Length = 866
Score = 1295 bits (3350), Expect = 0.0
Identities = 634/645 (98%), Positives = 635/645 (98%), Gaps = 4/645 (0%)
Query: 1 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 60
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW
Sbjct: 1 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW 60
Query: 61 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 120
NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA
Sbjct: 61 NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA 120
Query: 121 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 180
NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC
Sbjct: 121 NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC 180
Query: 181 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 240
RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ
Sbjct: 181 RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ 240
Query: 241 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 300
LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS
Sbjct: 241 LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS 300
Query: 301 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 360
GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW
Sbjct: 301 GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW 360
Query: 361 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 420
NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV
Sbjct: 361 NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 420
Query: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK
Sbjct: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
Query: 481 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 540
EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF
Sbjct: 481 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF 540
Query: 541 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS
Sbjct: 541 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
Query: 601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRG----IHTSPLGKPS 641
YKMADEAGSEADHEGTHSTKRGHAKSRPVR + T P G S
Sbjct: 601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQS 645
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 71.6 bits (174), Expect = 2e-12
Identities = 100/386 (25%), Positives = 139/386 (36%), Gaps = 32/386 (8%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
R G + YG+GS S R P +GS +S SG G +R+ SSG G +
Sbjct: 2423 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHS--SGLGHRESRSGQSSGYGQHGSSS 2480
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
SS G GS + SS G G + S G G+ + SS G G + +S G
Sbjct: 2481 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 2540
Query: 383 TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSG----NVSPGTRREYHTEKLVTSKG 438
G +S S+ GSG + + E SG S G Y S
Sbjct: 2541 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH---GSGS 2597
Query: 439 DKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG 498
G+ SG ++ R S + + + G G + GS ++ G
Sbjct: 2598 GHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGS-RQSSGHGRQGSGSGQSPSRG 2656
Query: 499 TL-SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLG--EFVSETESRGSESGIFT 555
SG+G H + S + G + LG + ES S +
Sbjct: 2657 RHGSGLG--------HSSSHGQHGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAY- 2707
Query: 556 NTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEG 615
S H G F S+G+ S S Q SST G ST +S SY S++ G
Sbjct: 2708 -----SQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSYGHRGSGSSQSSGYG 2760
Query: 616 THSTKRGHAKSRPVRGIHTSPLGKPS 641
H G + S G H S G+ S
Sbjct: 2761 RHGAGSGQSLS---HGRHGSGSGQSS 2783
Score = 69.7 bits (169), Expect = 8e-12
Identities = 100/391 (25%), Positives = 139/391 (35%), Gaps = 42/391 (10%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
R G + YG+GS S R P +GS S SSG G +R+ SSG G +
Sbjct: 1483 RHGSGSGQSSSYSPYGSGSGWSSSRGPYESGS--SHSSGLGHRESRSGQSSGYGQHGSSS 1540
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
SS G GS + SS G G + S G G+ + SS G G + +S G
Sbjct: 1541 GHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQ 1600
Query: 383 TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSG----NVSPGTRREYHTEKLVTSKG 438
G +S S+ GSG + + E SG S G Y S
Sbjct: 1601 RGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH---GSGS 1657
Query: 439 DKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG 498
G+ SG ++ R S + + + G G + GS ++ G
Sbjct: 1658 GHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGS-RQSSGHGRQGSGSGQSPSRG 1716
Query: 499 TL-SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNT 557
SG+G H + S + G + ESR S +F
Sbjct: 1717 RHGSGLG--------HSSSHGQHGSGSGRSSSRGPY-----------ESRSGHSSVFGQH 1757
Query: 558 KESSSHH-------PGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSE 610
+ S H G F S+G+ S S Q SST G ST +S S+ S+
Sbjct: 1758 ESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQ--SSTFDQEGSSTGQSSSHGQHGSGSSQ 1815
Query: 611 ADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
+ G + G + P RG H S G S
Sbjct: 1816 SSSYGQQGSGSGQS---PSRGRHGSGSGHSS 1843
Score = 65.1 bits (157), Expect = 2e-10
Identities = 96/409 (23%), Positives = 149/409 (36%), Gaps = 41/409 (10%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPG 324
G G +G GS R +GS +S S G +G+ SSG G+ + +
Sbjct: 1340 GSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSS 1399
Query: 325 SSGPGSTGSWNSG-----SSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
G + SW S SG+G + + R G + S GS+ + S
Sbjct: 1400 GFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSG 1459
Query: 380 S-GSTGQWHSESGSFRPDSP-------GSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S S G SGS + SP GSG + +P +G+ S + P H+
Sbjct: 1460 SRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP-YGSGSGWSSSRGPYESGSSHSS 1518
Query: 432 KLVTSKGDKELRTGKEK------VTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTS 485
L G +E R+G+ +SG ++T + S + + G G +
Sbjct: 1519 GL----GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS-GQSSSHG 1573
Query: 486 EDGSDCPEAMDLGTL-SGIGTLDGFRH-----RHPDEAAFFDTASTGKTFPGFFSPMLGE 539
+ GS ++ G SG G G R + S + G LGE
Sbjct: 1574 QHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGE 1633
Query: 540 F--VSETESRGSESGIFTNTKESSSHHPGIAEFPSR-GKSSSYSKQFTSSTSYNR----G 592
ES +S ++ S H G + SR G+SS + +SS S +R G
Sbjct: 1634 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHG 1693
Query: 593 DSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
+ +S + ++ G H + GH+ S G H S G+ S
Sbjct: 1694 SGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSS---HGQHGSGSGRSS 1739
Score = 64.7 bits (156), Expect = 3e-10
Identities = 101/415 (24%), Positives = 153/415 (36%), Gaps = 55/415 (13%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAG---------SWNSGSSGPGSTGNRNPGSSGT 315
G ++ + G G+G R+ S +G S + SS G G+ + SSG
Sbjct: 1812 GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 1871
Query: 316 G--GTATWKPGSSGPGSTGSWNSGS-------SGTGSTGNQNPGSPRPGSTGTWNPGSSE 366
G +++W+ +GS +S S SG S G Q+ GS S+ GS
Sbjct: 1872 GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQH-GSSSGSSSSYGQHGSGS 1930
Query: 367 RGSAGH-------WTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
R S GH S S G G +S S+ P GSG + P +E SG+
Sbjct: 1931 RQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYGSGSGWSSSRGP----YESGSGH 1986
Query: 420 VSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVT 479
S RE S+ + G+ +SG ++T + S + + G G
Sbjct: 1987 SSGLGHRE--------SRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASS-G 2037
Query: 480 KEVVTSEDGSDCPEAMDLGTL-SGIGTLDGFRH-----RHPDEAAFFDTASTGKTFPGFF 533
+ + GS ++ G SG G G R + S + G
Sbjct: 2038 QSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQH 2097
Query: 534 SPMLGEF--VSETESRGSESGIFTNTKESSSHHPGIAEFPSR-GKSSSYSKQFTSSTSYN 590
P LGE ES +S ++ S H G + SR G+SS + +SS S +
Sbjct: 2098 GPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSS 2157
Query: 591 R----GDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
R G + +S + + G H + GH+ S G H S G+ S
Sbjct: 2158 RYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSS---HGQHGSGSGRSS 2209
Score = 62.8 bits (151), Expect = 1e-09
Identities = 91/394 (23%), Positives = 144/394 (36%), Gaps = 36/394 (9%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
+ PG + G S +G SS+G + SGS G+ S + G
Sbjct: 422 QSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYT-- 479
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWT----SES 377
+ GS S+G GS S+ + GS S+ GS R S GH S
Sbjct: 480 QHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQ 539
Query: 378 SVSGSTGQWHS---ESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLV 434
S S S G+ S +S S+ P GSG + P +E SG+ S +E
Sbjct: 540 SPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGP----YESGSGHSSGLGHQE------- 588
Query: 435 TSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEA 494
S+ + G+ +SG ++T + S + + G G + + GS ++
Sbjct: 589 -SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGATS-GQSSSHGQHGSGSSQS 646
Query: 495 MDLGTLSGIGTLDGFRHRHPDE---AAFFDTASTGKTFPGFFSPMLGEFVSETESRGSES 551
G R RH + ++ + +G + P G ++ G +S
Sbjct: 647 SRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSSSNGPH-GSVSGQSSGFGHKS 705
Query: 552 GI-----FTNTKESSSHHPGIAEFPSRGKSSSYSKQFTS----STSYNR-GDSTFESKSY 601
G ++ SSH G + SR SS S+Q S S+SY + G + +S +
Sbjct: 706 GSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGH 765
Query: 602 KMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTS 635
+ H + GH+ S G TS
Sbjct: 766 GRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTS 799
Score = 62.8 bits (151), Expect = 1e-09
Identities = 94/401 (23%), Positives = 139/401 (34%), Gaps = 54/401 (13%)
Query: 265 GGNEITRGGSTSYGTG------SETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGT 318
G E G S+ YG S T +S S + G G S + + G G+G +
Sbjct: 1991 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSS 2050
Query: 319 ATWKPGSSGPGSTGSWNSGSSGTGST-----GNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
+ G G GS S G G+GS G GS R S+G PG E GH
Sbjct: 2051 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHH 2110
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVS-------GNVSPGTRR 426
S S S S Q SGS G +R G S G G+R+
Sbjct: 2111 ESSSGQSSSYSQ--HGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQ 2168
Query: 427 EYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGP----DGHKEVTKEV 482
+ + G R G+ SG +++ + S + + GP GH V +
Sbjct: 2169 SSGHGRQGSGSGHSPSR-GRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQ- 2226
Query: 483 VTSEDGSDCPEAMDL-GTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFV 541
E GS A G+ SG G +++ FD G
Sbjct: 2227 --HESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE--------------GSST 2270
Query: 542 SETESRGSESGIFTNTKESSSHHPGIAEFPSRGK-------SSSYSKQFT----SSTSYN 590
++ S G + + G + PSRG+ SSSY + + SS+S
Sbjct: 2271 GQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGR 2330
Query: 591 RGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRG 631
G + +S + + + ++ H + GH+ S G
Sbjct: 2331 HGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHG 2371
Score = 62.4 bits (150), Expect = 1e-09
Identities = 100/419 (23%), Positives = 147/419 (35%), Gaps = 59/419 (14%)
Query: 265 GGNEITRGGSTSYG---TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
G ++ + G S+SYG + S S R +GS S G +G+ S G G+ +
Sbjct: 855 GQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSG 914
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
+ SSG +GS S G S+ Q+ G + GS + + GS +S S G
Sbjct: 915 RSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHG 974
Query: 382 ST------------------GQWHSESGSFRPDSP-------GSGNARPNNP-----DW- 410
S+ G SGS + SP GSG + P W
Sbjct: 975 SSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWS 1034
Query: 411 ---GTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTK 467
G +E SG+ S RE S+ + G+ +SG ++T + S +
Sbjct: 1035 SSRGPYESGSGHSSGLGHRE--------SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQS 1086
Query: 468 TVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL-SGIGTLDGFRHRHPDEAAFFDTASTG 526
+ G G + + GS ++ G SG G G R + S G
Sbjct: 1087 SSCGQHGASS-GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSR---QSPSYG 1142
Query: 527 KTFPG----FFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQ 582
+ G S G + E+ G + S H G G+ S S Q
Sbjct: 1143 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 1202
Query: 583 FTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
SS G S+ S Y ++ G + GH+ P RG H S LG S
Sbjct: 1203 --SSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHS---PSRGRHGSGLGHSS 1256
Score = 60.8 bits (146), Expect = 4e-09
Identities = 101/390 (25%), Positives = 144/390 (36%), Gaps = 38/390 (9%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPG---SSGTGGTATWKPGSSGP 328
G S G G R S G SGS S+G G SSG G + SS
Sbjct: 1121 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSY 1180
Query: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
GS + SSG G G+++ S R G+ + SS G G + +SS G G
Sbjct: 1181 SQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSG 1240
Query: 389 ESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEK 448
S S G G++ ++ G+ S + P R H+ G E +G
Sbjct: 1241 HSPSRGRHGSGLGHS-SSHGQHGSGSGRSSSRGPYESRSGHSSVF----GQHESGSGHSS 1295
Query: 449 VTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL-SGIGTLD 507
S + + CS+ + G + ++GS ++ G SG
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSG--------QSSTFDQEGSSTGQSSSYGHRGSGSSQSS 1347
Query: 508 GF-RHRHPDEAAFFDTASTGKTFPGF-FSPMLGE------FVSETESRGSESGI---FTN 556
G+ RH A + S G+ G S G+ + S + GS SG F +
Sbjct: 1348 GYGRH----GAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1403
Query: 557 TKESSSHHPGIAEFPS-RGKSSSY----SKQFTSSTSYNRGDSTFESKSYKMADEAGSEA 611
+ SS G + S G SSSY S+ SS G S+ S SY ++
Sbjct: 1404 HESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 1463
Query: 612 DHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
G H + G + S P RG H S G+ S
Sbjct: 1464 LGHGQHGSGSGQSPS-PSRGRHGSGSGQSS 1492
Score = 60.5 bits (145), Expect = 5e-09
Identities = 95/414 (22%), Positives = 150/414 (36%), Gaps = 53/414 (12%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAG---------SWNSGSSGPGSTGNRNPGSSGT 315
G ++ + G G+G R+ S +G S + SS G G+ + SSG
Sbjct: 2282 GSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGF 2341
Query: 316 G--GTATWKPG-----SSGPGSTGSWNSGSSGTG-STGNQNPGSPRPGSTGTWNPGSSER 367
G +++W+ SG G + S+ S +G S+ + GS S+ GS R
Sbjct: 2342 GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 2401
Query: 368 GSAGH-------WTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV 420
S GH S S G G +S S+ P GSG + P +E SG+
Sbjct: 2402 QSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGP----YESGSGHS 2457
Query: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
S RE S+ + G+ +SG ++T + S + + G G +
Sbjct: 2458 SGLGHRE--------SRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS-GQ 2508
Query: 481 EVVTSEDGSDCPEAMDLGTL-SGIGTLDGFRH-----RHPDEAAFFDTASTGKTFPGFFS 534
+ GS ++ G SG G G R + S + G
Sbjct: 2509 SSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHG 2568
Query: 535 PMLGEF--VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYN-- 590
LGE ES +S ++ S H G + SR SS ++ SS+ +
Sbjct: 2569 SGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSH 2628
Query: 591 ---RGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
G + +S + ++ G H + GH+ S G H S G+ S
Sbjct: 2629 YGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSS---HGQHGSGSGRSS 2679
Score = 58.9 bits (141), Expect = 1e-08
Identities = 97/392 (24%), Positives = 140/392 (35%), Gaps = 29/392 (7%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
R G G G+GS +GS S SSG G SSG G +
Sbjct: 2057 RQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGE--SSGFGHHESSS 2114
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
SS GS + SSG G G+++ S R G+ + SS G G + +SS G
Sbjct: 2115 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGR 2174
Query: 383 TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL 442
G S S GSG++ ++ G+ S + P R H+ G E
Sbjct: 2175 QGSGSGHSPSRGRHGSGSGHS-SSHGQHGSGSGRSSSRGPYESRSGHSSVF----GQHES 2229
Query: 443 RTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDG-----HKEVTKEVVTSEDGSDCPEAMDL 497
+G S + + CS+ + G + + GS ++
Sbjct: 2230 GSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSY 2289
Query: 498 GTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGI---F 554
G R RH + ++S G+ G + S + GS SG F
Sbjct: 2290 GQQGSGSGQSPSRGRHGSGSG--HSSSYGQHGSG------SGWSSSSGRHGSGSGQSSGF 2341
Query: 555 TNTKESSSHHPGIAEFPS-RGKSSSY----SKQFTSSTSYNRGDSTFESKSYKMADEAGS 609
+ + SS G + S G SSSY S+ SS G S+ S SY
Sbjct: 2342 GHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSR 2401
Query: 610 EADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
++ G H + G + S P RG H S G+ S
Sbjct: 2402 QSLGHGQHGSGSGQSPS-PSRGRHGSGSGQSS 2432
Score = 58.5 bits (140), Expect = 2e-08
Identities = 110/438 (25%), Positives = 164/438 (37%), Gaps = 59/438 (13%)
Query: 235 GNFKSQLQKVPPEWKALTDMPQMRMELERP--GGNEITRGGSTSYG---TGSETESPRNP 289
G S + V K T+ R+ +R G + G S+SYG + S S R
Sbjct: 135 GENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYGEQNSDSHQSSGRGQ 194
Query: 290 SSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPG-----------SSGPGSTGSWNSGS 338
+GS S + G +G+ S+ T G+ + + SSG GS + S
Sbjct: 195 CGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS 254
Query: 339 SGTGSTGNQNPGSPR-------PGSTGTWNP-GSSERGSAGHWTSESSVSGSTGQWHSES 390
SG G G+++ S R GS+ ++ GS R S GH S S S
Sbjct: 255 SGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGS 314
Query: 391 GSFRPDSPGS-GNARPNNPDWGTFEEVSGNVS------PGTRREYHTEKLVTSKGDKELR 443
GS S G G+ + G +E SG S G+ + K + G +
Sbjct: 315 GSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQ 374
Query: 444 TGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGI 503
G+ TSG +++ + S + + G H+ ++ +S G SG
Sbjct: 375 -GQHGSTSGQASSSGQHGSSSRQSSSYGQ--HESASRH--SSGRGQHS---------SGS 420
Query: 504 GTLDGFRHRHPDEAAFFDTASTGKTFPGF-FSPMLGEFVSETESRGSESGIFTNTKESSS 562
G G R + S+G+ GF S G +VS G SG F + + SS
Sbjct: 421 GQSPGHGQRGSGSG---QSPSSGQHGTGFGRSSSSGPYVS---GSGYSSG-FGHHESSSE 473
Query: 563 HHPGIAEFPS-RGKSSSY----SKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTH 617
H G + S G SS + S+ SS +G S S SY ++ H
Sbjct: 474 HSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRH 533
Query: 618 STKRGHAKSRPVRGIHTS 635
+ G + S P RG H S
Sbjct: 534 GSGSGQSPS-PSRGRHES 550
Score = 58.5 bits (140), Expect = 2e-08
Identities = 92/390 (23%), Positives = 129/390 (33%), Gaps = 63/390 (16%)
Query: 265 GGNEITRGGSTSYGTG------SETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGT 318
G E G S+ YG S T +S S + G G S + + G G+G +
Sbjct: 1521 GHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSS 1580
Query: 319 ATWKPGSSGPGSTGSWNSGSSGTGST-----GNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
+ G G GS S G G+GS G GS R S+G G E GH
Sbjct: 1581 QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHH 1640
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKL 433
S S S S +S+ GS S G G + E + +R H
Sbjct: 1641 ESSSGQSSS----YSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGS 1696
Query: 434 VTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPE 493
S G G++ SG + + R S GH +S G
Sbjct: 1697 RQSSGH-----GRQGSGSGQSPSRGRHGSGL---------GH--------SSSHGQH--- 1731
Query: 494 AMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGI 553
G+ SG + G ++ F +G +S GS SG
Sbjct: 1732 ----GSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS-----------QHGSGSGH 1776
Query: 554 FTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADH 613
F + + S + F G S+ SS+ G + +S SY ++
Sbjct: 1777 FCSQGQHGSTSGQSSTFDQEGSSTG-----QSSSHGQHGSGSSQSSSYGQQGSGSGQSPS 1831
Query: 614 EGTHSTKRGHAKSRPVRGIHTSPLGKPSLS 643
G H + GH+ S G H S G S S
Sbjct: 1832 RGRHGSGSGHSSS---YGQHGSGSGWSSSS 1858
Score = 58.5 bits (140), Expect = 2e-08
Identities = 100/396 (25%), Positives = 142/396 (35%), Gaps = 43/396 (10%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSG---SSGPGSTGNRNPGSSGTGGT 318
+ PG + G S G SS+G SG SSG G + + SS
Sbjct: 1594 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 1653
Query: 319 ATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESS 378
+ SSG G GS + SS G+ + S R G G+ + SS G G + +S
Sbjct: 1654 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSP 1713
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREY---HTEKLVT 435
G G S S GSG + P +E SG+ S + E H+
Sbjct: 1714 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGP----YESRSGHSSVFGQHESGSGHSSAYSQ 1769
Query: 436 --SKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPE 493
S G+ TSG ++T + S T + G + GS +
Sbjct: 1770 HGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHG--------------QHGSGSSQ 1815
Query: 494 AMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGI 553
+ G R RH + ++S G+ G + S + GS SG
Sbjct: 1816 SSSYGQQGSGSGQSPSRGRHGSGSG--HSSSYGQHGSG------SGWSSSSGRHGSGSGQ 1867
Query: 554 ---FTNTKESSSHHPGIAEFPS-RGKSSSY----SKQFTSSTSYNRGDSTFESKSYKMAD 605
F + + SS G + S G SSSY S+ SS G S+ S SY
Sbjct: 1868 SSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG 1927
Query: 606 EAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
++ G H + G + S P RG H S G+ S
Sbjct: 1928 SGSRQSLGHGQHGSGSGQSPS-PSRGRHGSGSGQSS 1962
Score = 57.8 bits (138), Expect = 3e-08
Identities = 94/394 (23%), Positives = 137/394 (34%), Gaps = 48/394 (12%)
Query: 272 GGSTSYG-----TGSETESPRNPSSAGSWNS-GSSGPGSTGNRNPGSSGTGGTATWK--- 322
G S+ YG +G + R+ SS+GS +S G G GS + G G+G +
Sbjct: 252 GHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVR 311
Query: 323 --PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
GS S G SGSS + S G+ GS + G GS + S S S
Sbjct: 312 HGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHS 371
Query: 381 GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDK 440
S GQ S SG S G++ + +G E S + S R H+ S G
Sbjct: 372 SSQGQHGSTSGQ-ASSSGQHGSSSRQSSSYGQHESASRHSS---GRGQHSSGSGQSPGHG 427
Query: 441 ELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL 500
+ +G + S T S + V G +SE S +
Sbjct: 428 QRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQH------ 481
Query: 501 SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKES 560
G+ G H + +S G+ G + S G +
Sbjct: 482 ---GSGSGHSSGHGQHGSRSGQSSRGE--------RQGSSAGSSSSYGQHGSGSRQSLGH 530
Query: 561 SSHHPGIAE--FPSRGKSSSYSKQFTSSTSYNRGDSTFESKS-YKMADEAGSEADHE--- 614
S H G + PSRG+ S S+Q +S + G S+ Y+ S H+
Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
Query: 615 -------GTHSTKRGHAKSRPVRGIHTSPLGKPS 641
G H + GH+ + G H S G+ S
Sbjct: 591 SGQSSGYGQHGSSSGHSST---HGQHGSTSGQSS 621
Score = 54.7 bits (130), Expect = 3e-07
Identities = 95/375 (25%), Positives = 136/375 (36%), Gaps = 53/375 (14%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
G S+ +G S + S GS +S SSG G+R+ SS + + SS G
Sbjct: 696 GQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQH 755
Query: 332 GSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391
GS + SSG G G+ + SP G+ + SS G G TS SS G ++
Sbjct: 756 GSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQAS 815
Query: 392 SFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTS 451
F GSG + SG+ S R S + +G+ +S
Sbjct: 816 GFGQHESGSGQG------YSQHGSASGHFSSQGRH--------GSTSGQSSSSGQHDSSS 861
Query: 452 GSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRH 511
G +++ + S + + G G P G+ SG G
Sbjct: 862 GQSSSYGQHESASHHASGRGRHG-----------SGSGQSPGHGQRGSGSGQSPSYG--- 907
Query: 512 RHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFP 571
RH + ++S+G+ G G SG K SS G +
Sbjct: 908 RHGSGSG--RSSSSGRHGSG---------------SGQSSGF--GHKSSSGQSSGYTQHG 948
Query: 572 S-RGKSSSY----SKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKS 626
S G SSSY S+ SS S G S+ S SY ++ G H + G + S
Sbjct: 949 SGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1008
Query: 627 RPVRGIHTSPLGKPS 641
P RG H S G+ S
Sbjct: 1009 -PSRGRHGSGSGQSS 1022
Score = 51.6 bits (122), Expect = 2e-06
Identities = 46/171 (26%), Positives = 68/171 (39%), Gaps = 15/171 (8%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
ER G + + +G+GS S +GS +S S G +G+ + S G G+ +
Sbjct: 2147 ERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHSSSHGQHGSGSG 2206
Query: 322 KPGSSGPGST--------GSWNSGSSGTGSTGNQNPGSPR---PGSTGTWNPGSSERGSA 370
+ S GP + G SGS + + GS G G+ + SS
Sbjct: 2207 RSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 2266
Query: 371 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVS 421
G T +SS G G S+S S+ GSG +P G SG+ S
Sbjct: 2267 GSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG----QSPSRGRHGSGSGHSS 2313
Score = 51.2 bits (121), Expect = 3e-06
Identities = 82/367 (22%), Positives = 119/367 (32%), Gaps = 65/367 (17%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
G + +G+GS S + + S + SSG + +R S G +A+ G S+G
Sbjct: 360 GYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSG 419
Query: 333 SWNS--------GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTG 384
S S GS + S+G G R S+G + GS GH ESS S+G
Sbjct: 420 SGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGH--HESSSEHSSG 477
Query: 385 QWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRT 444
SGS G +R G E G+ S G+ Y + + R
Sbjct: 478 YTQHGSGSGHSSGHGQHGSRSGQSSRG---ERQGS-SAGSSSSYGQHGSGSRQSLGHSRH 533
Query: 445 GKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIG 504
G S S + R S + + GP G+ + S P G SG+G
Sbjct: 534 GSGSGQSPSPSRGRHE-SGSRQSSSYGPHGYG-------SGRSSSRGPYESGSGHSSGLG 585
Query: 505 TLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHH 564
ESR +S + SS H
Sbjct: 586 --------------------------------------HQESRSGQSSGYGQHGSSSGHS 607
Query: 565 PGIAEFPSRGKSSSYSKQF-----TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHST 619
+ S SS Q SS+ G + +S Y ++ G H +
Sbjct: 608 STHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGS 667
Query: 620 KRGHAKS 626
GH+ S
Sbjct: 668 DFGHSSS 674
Score = 50.1 bits (118), Expect = 6e-06
Identities = 90/383 (23%), Positives = 141/383 (36%), Gaps = 58/383 (15%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAG---SWNSGSSGPGSTGNRNPGSSGTGGTATW 321
G + + G G+G R+ S G S SG G + +R P S +G ++ +
Sbjct: 1225 GSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVF 1284
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERG---SAGHWTSESS 378
SG G + +++ SG+G +Q G + T++ S G S GH S SS
Sbjct: 1285 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 1344
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRR----------EY 428
S G+ + SG P G+ ++ +G SG S R +
Sbjct: 1345 QSSGYGRHGAGSGQ-SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 1403
Query: 429 HTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDG 488
H S G + +G SG +++ + S++ G E G
Sbjct: 1404 HESSSWQSSGCTQHGSG-----SGHSSSYEQHGSRS------GQSSRGE--------RHG 1444
Query: 489 SDCPEAMDLGTLSGIGTLDGFRH-RHPDEAAFFDTASTGKTFPG-----FFSPMLGEFVS 542
S + G G G+ H +H + + S G+ G +SP G
Sbjct: 1445 SSSGSSSSYGQ-HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSP-YGSGSG 1502
Query: 543 ETESRGS-ESGIFTNTKESSSHHPGIAEFPSR-GKSSSY----SKQFTSSTSYNRGDSTF 596
+ SRG ESG SSH G+ SR G+SS Y S SST G ++
Sbjct: 1503 WSSSRGPYESG--------SSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
Query: 597 ESKSYKMADEAGSEADHEGTHST 619
+S S + ++ G H +
Sbjct: 1555 QSSSCGQHGASSGQSSSHGQHGS 1577
Score = 46.6 bits (109), Expect = 7e-05
Identities = 40/153 (26%), Positives = 59/153 (38%), Gaps = 11/153 (7%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
ER G + + +G+GS S +GS S S G +G + S G G+ +
Sbjct: 2617 ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSG 2676
Query: 322 KPGSSGPGST--------GSWNSGSSGTGSTGNQNPGSPR---PGSTGTWNPGSSERGSA 370
+ S GP + G SGS + + GS G G+ + SS
Sbjct: 2677 RSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQE 2736
Query: 371 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNA 403
G T +SS G G S+S + GSG +
Sbjct: 2737 GSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQS 2769
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 3/150 (2%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSG---SSGPGSTGNRNPGSSGTGGT 318
+ PG + G S G SS+G SG SSG G + + SS
Sbjct: 2534 QSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQH 2593
Query: 319 ATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESS 378
+ SSG G GS + SS G+ + S G G+ + SS G G + +S
Sbjct: 2594 GSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSP 2653
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNP 408
G G S S GSG + P
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSGSGRSSSRGP 2683
Score = 42.4 bits (98), Expect = 0.001
Identities = 39/136 (28%), Positives = 56/136 (41%), Gaps = 11/136 (8%)
Query: 277 YGTGSETESPRNPSSAGSWNSG-----SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
+G+GS S R P + +S SG G + + SG+G + S G +
Sbjct: 2671 HGSGSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQS 2730
Query: 332 GSWNSGSSGTG---STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
+++ S TG S G++ GS + G GS + S G S S S S GQ S
Sbjct: 2731 STFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGS 2790
Query: 389 ESG---SFRPDSPGSG 401
SG + GSG
Sbjct: 2791 GSGQSSGYSQHGSGSG 2806
Score = 41.6 bits (96), Expect = 0.002
Identities = 86/414 (20%), Positives = 140/414 (33%), Gaps = 71/414 (17%)
Query: 271 RGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGS 330
R GS+S + S + S + S SG G SG+G + +SG S
Sbjct: 780 RHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSASGHFS 839
Query: 331 TGSWNSGSSGTGSTGNQN--------------------PGSPRPGSTGTWNPGSSERGSA 370
+ + +SG S+ Q+ G R GS +PG +RGS
Sbjct: 840 SQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSG 899
Query: 371 -------GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPG 423
G S S S S+G+ S SG S G G+ + G + SG+
Sbjct: 900 SGQSPSYGRHGSGSGRSSSSGRHGSGSG----QSSGFGHKSSSGQSSGYTQHGSGSGHSS 955
Query: 424 TRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGH-KEVTKEV 482
+ ++ S+ + R+ + +SGS+++ + S + G G +
Sbjct: 956 SYEQH------GSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSP 1009
Query: 483 VTSEDGSDCPEAMDLGTL--------------SGIGTLDGFRHRHPDEAAFFDTASTGKT 528
GS ++ G SG G G HR E+ ++ G+
Sbjct: 1010 SRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHR---ESRSGQSSGYGQH 1066
Query: 529 FPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTS 588
G + + G + H + S G+ S S Q S+
Sbjct: 1067 ---------GSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQ---SSG 1114
Query: 589 YNR-GDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPS 641
Y R G + +S + ++ G H + G + S G H S LG+ S
Sbjct: 1115 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS---SGQHGSGLGESS 1165
Score = 38.5 bits (88), Expect = 0.019
Identities = 43/147 (29%), Positives = 60/147 (40%), Gaps = 18/147 (12%)
Query: 265 GGNEITRGGSTSY---GTGS-------ETESPRNPSSAGSWNSGSSGPGST-GNRNPGSS 313
G +E G S++Y G+GS + S SS S+G S+ G+R GSS
Sbjct: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSS 2754
Query: 314 GTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
+ G G G GS S + G G+GS Q+ + GS + G S+ GS
Sbjct: 2755 QSSGY-----GRHGAGSGQSLSHGRHGSGS--GQSSSYGQHGSGSGQSSGYSQHGSGSGQ 2807
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGS 400
S G + SGS+ P S
Sbjct: 2808 DGYSYCKGGSNHDGGSSGSYFLSFPSS 2834
Score = 36.2 bits (82), Expect = 0.096
Identities = 38/140 (27%), Positives = 57/140 (40%), Gaps = 18/140 (12%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNS-----GSSGPGSTGNRNPGSSGTGGTATWKPGSSG 327
G G+G + ++ S +G + S +SG ST ++ S+G + G G
Sbjct: 2695 GQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSY----GHRG 2750
Query: 328 PGSTGSWNSGSSGTG-----STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
GS+ S G G G S G GS + S G GS G + ++ S SG
Sbjct: 2751 SGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS---GQSSGYSQHGSGSGQ 2807
Query: 383 TGQWHSESGSFRPDSPGSGN 402
G + + GS D SG+
Sbjct: 2808 DGYSYCKGGS-NHDGGSSGS 2826
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 67.4 bits (163), Expect = 4e-11
Identities = 55/165 (33%), Positives = 78/165 (47%), Gaps = 13/165 (7%)
Query: 265 GGNEITRGGSTSYGT---GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
GGN GG ++GT G+ + A + N G + P +G+ GSS +GG +
Sbjct: 196 GGN----GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG-GSSNSGGGSGS 250
Query: 322 KPGSSGPGSTGSWNSGSS-GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
+ GSSG GS G N+GSS G S+G+ + GS S G+ RG +G +S S +
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310
Query: 381 GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEE--VSGNVSPG 423
GS+ H SG PG +P N G+ E + SPG
Sbjct: 311 GSSSGNHGGSGGGNGHKPGC--EKPGNEARGSGESGIQNSETSPG 353
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 31/150 (20%)
Query: 290 SSAGSWNSGSSGP--GSTGNRNPGSSGTG--------------------GTATWKPGSSG 327
+SAGS+ G G GN P + GT G P SG
Sbjct: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
Query: 328 PGSTGSW-----NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES----S 378
GS+ S SGSSG+GS G+ N GS GS+ + G S GS+G + S
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNP 408
SGS W S +GS + GSG + P
Sbjct: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Score = 54.3 bits (129), Expect = 3e-07
Identities = 52/141 (36%), Positives = 69/141 (48%), Gaps = 33/141 (23%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
GGS++ G GS ++S GSSG GS G+ N GSS G ++ GSS GS+
Sbjct: 239 GGSSNSGGGSGSQS------------GSSGSGSNGDNNNGSSSGGSSS----GSSSGGSS 282
Query: 332 GSWNSGSSGT--GSTGNQNPGSPRPGSTG--TWNPGSSERGSAGHWT------SESSVSG 381
G + GSSG GS G+ S STG + N G S G+ GH +E+ SG
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN-GHKPGCEKPGNEARGSG 341
Query: 382 STGQWHSESGSFRPDSPGSGN 402
+G +SE+ SPG N
Sbjct: 342 ESGIQNSET------SPGMFN 356
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/130 (31%), Positives = 56/130 (43%), Gaps = 13/130 (10%)
Query: 288 NPSSAGSWNSGSSGPGSTGNRNPGSSGTGG-----TATWKPGSSGPGSTGSWNSGSSGTG 342
NP A G+ GP + G G+ G + G + P +GS S+ G
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 343 STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
+G+Q+ GS GS G N GSS GS+ S SS GS+G SG +S GS
Sbjct: 247 GSGSQS-GSSGSGSNGDNNNGSSSGGSS----SGSSSGGSSG---GSSGGSSGNSGGSRG 298
Query: 403 ARPNNPDWGT 412
+ WG+
Sbjct: 299 DSGSESSWGS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 14/175 (8%)
Query: 264 PGGNEI--TRGGSTSYGT--GSETESPRNPSSAGS-WNSGSSG--PGSTGNRNPGSSGTG 316
PG N T GG +G+ G + NP G+ W G G GS G NP + G
Sbjct: 136 PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGAPWG 194
Query: 317 GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
P + G + G+ G+ NQN G P +G+ S+ G +G
Sbjct: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG----- 249
Query: 377 SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S SGS+G + + S GS + + G S S G+R + +E
Sbjct: 250 -SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 67.4 bits (163), Expect = 4e-11
Identities = 55/165 (33%), Positives = 78/165 (47%), Gaps = 13/165 (7%)
Query: 265 GGNEITRGGSTSYGT---GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
GGN GG ++GT G+ + A + N G + P +G+ GSS +GG +
Sbjct: 196 GGN----GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG-GSSNSGGGSGS 250
Query: 322 KPGSSGPGSTGSWNSGSS-GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
+ GSSG GS G N+GSS G S+G+ + GS S G+ RG +G +S S +
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310
Query: 381 GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEE--VSGNVSPG 423
GS+ H SG PG +P N G+ E + SPG
Sbjct: 311 GSSSGNHGGSGGGNGHKPGC--EKPGNEARGSGESGIQNSETSPG 353
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 31/150 (20%)
Query: 290 SSAGSWNSGSSGP--GSTGNRNPGSSGTG--------------------GTATWKPGSSG 327
+SAGS+ G G GN P + GT G P SG
Sbjct: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
Query: 328 PGSTGSW-----NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES----S 378
GS+ S SGSSG+GS G+ N GS GS+ + G S GS+G + S
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNP 408
SGS W S +GS + GSG + P
Sbjct: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Score = 54.3 bits (129), Expect = 3e-07
Identities = 52/141 (36%), Positives = 69/141 (48%), Gaps = 33/141 (23%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
GGS++ G GS ++S GSSG GS G+ N GSS G ++ GSS GS+
Sbjct: 239 GGSSNSGGGSGSQS------------GSSGSGSNGDNNNGSSSGGSSS----GSSSGGSS 282
Query: 332 GSWNSGSSGT--GSTGNQNPGSPRPGSTG--TWNPGSSERGSAGHWT------SESSVSG 381
G + GSSG GS G+ S STG + N G S G+ GH +E+ SG
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGN-GHKPGCEKPGNEARGSG 341
Query: 382 STGQWHSESGSFRPDSPGSGN 402
+G +SE+ SPG N
Sbjct: 342 ESGIQNSET------SPGMFN 356
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/130 (31%), Positives = 56/130 (43%), Gaps = 13/130 (10%)
Query: 288 NPSSAGSWNSGSSGPGSTGNRNPGSSGTGG-----TATWKPGSSGPGSTGSWNSGSSGTG 342
NP A G+ GP + G G+ G + G + P +GS S+ G
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 343 STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
+G+Q+ GS GS G N GSS GS+ S SS GS+G SG +S GS
Sbjct: 247 GSGSQS-GSSGSGSNGDNNNGSSSGGSS----SGSSSGGSSG---GSSGGSSGNSGGSRG 298
Query: 403 ARPNNPDWGT 412
+ WG+
Sbjct: 299 DSGSESSWGS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 14/175 (8%)
Query: 264 PGGNEI--TRGGSTSYGT--GSETESPRNPSSAGS-WNSGSSG--PGSTGNRNPGSSGTG 316
PG N T GG +G+ G + NP G+ W G G GS G NP + G
Sbjct: 136 PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGAPWG 194
Query: 317 GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
P + G + G+ G+ NQN G P +G+ S+ G +G
Sbjct: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG----- 249
Query: 377 SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S SGS+G + + S GS + + G S S G+R + +E
Sbjct: 250 -SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 66.2 bits (160), Expect = 9e-11
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 11/154 (7%)
Query: 265 GGNEITRGGSTSYGT---GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
GGN GG ++GT G+ + A + N G + P +G+ GSS +GG +
Sbjct: 196 GGN----GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG-GSSNSGGGSGS 250
Query: 322 KPGSSGPGSTGSWNSGSS-GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
+ GSSG GS G N+GSS G S+G+ + GS S G+ RG +G +S S +
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310
Query: 381 GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFE 414
GS+ H SG PG +P N G+ E
Sbjct: 311 GSSSGNHGGSGGGNGHKPGC--EKPGNEARGSGE 342
Score = 63.5 bits (153), Expect = 6e-10
Identities = 49/142 (34%), Positives = 67/142 (47%), Gaps = 16/142 (11%)
Query: 265 GGNEITRGGSTSY----GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
GG+ + GGS S G+GS ++ N SS+G +SGSS GS+G + GSSG G
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDN-NNGSSSGGSSSGSSSGGSSGGSSGGSSGNSG--- 294
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
G +GS +S S TGS+ + GS G PG + G+ + ES +
Sbjct: 295 -----GSRGDSGSESSWGSSTGSSSGNHGGS---GGGNGHKPGCEKPGNEARGSGESGIQ 346
Query: 381 GSTGQWHSESGSFRPDSPGSGN 402
G GQ S + SPG N
Sbjct: 347 GFRGQGVSSNMRNSETSPGMFN 368
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 31/150 (20%)
Query: 290 SSAGSWNSGSSGP--GSTGNRNPGSSGTG--------------------GTATWKPGSSG 327
+SAGS+ G G GN P + GT G P SG
Sbjct: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
Query: 328 PGSTGSW-----NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES----S 378
GS+ S SGSSG+GS G+ N GS GS+ + G S GS+G + S
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNP 408
SGS W S +GS + GSG + P
Sbjct: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/130 (31%), Positives = 56/130 (43%), Gaps = 13/130 (10%)
Query: 288 NPSSAGSWNSGSSGPGSTGNRNPGSSGTGG-----TATWKPGSSGPGSTGSWNSGSSGTG 342
NP A G+ GP + G G+ G + G + P +GS S+ G
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 343 STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
+G+Q+ GS GS G N GSS GS+ S SS GS+G SG +S GS
Sbjct: 247 GSGSQS-GSSGSGSNGDNNNGSSSGGSS----SGSSSGGSSG---GSSGGSSGNSGGSRG 298
Query: 403 ARPNNPDWGT 412
+ WG+
Sbjct: 299 DSGSESSWGS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 14/175 (8%)
Query: 264 PGGNEI--TRGGSTSYGT--GSETESPRNPSSAGS-WNSGSSG--PGSTGNRNPGSSGTG 316
PG N T GG +G+ G + NP G+ W G G GS G NP + G
Sbjct: 136 PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGAPWG 194
Query: 317 GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
P + G + G+ G+ NQN G P +G+ S+ G +G
Sbjct: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG----- 249
Query: 377 SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S SGS+G + + S GS + + G S S G+R + +E
Sbjct: 250 -SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 66.2 bits (160), Expect = 9e-11
Identities = 52/154 (33%), Positives = 74/154 (48%), Gaps = 11/154 (7%)
Query: 265 GGNEITRGGSTSYGT---GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
GGN GG ++GT G+ + A + N G + P +G+ GSS +GG +
Sbjct: 196 GGN----GGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGG-GSSNSGGGSGS 250
Query: 322 KPGSSGPGSTGSWNSGSS-GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
+ GSSG GS G N+GSS G S+G+ + GS S G+ RG +G +S S +
Sbjct: 251 QSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSST 310
Query: 381 GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFE 414
GS+ H SG PG +P N G+ E
Sbjct: 311 GSSSGNHGGSGGGNGHKPGC--EKPGNEARGSGE 342
Score = 60.1 bits (144), Expect = 6e-09
Identities = 44/125 (35%), Positives = 62/125 (49%), Gaps = 16/125 (12%)
Query: 265 GGNEITRGGSTSY----GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
GG+ + GGS S G+GS ++ N SS+G +SGSS GS+G + GSSG G +
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDN-NNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSR 297
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVS 380
G +GS +S S TGS+ + GS G PG + G+ + ES +
Sbjct: 298 --------GDSGSESSWGSSTGSSSGNHGGS---GGGNGHKPGCEKPGNEARGSGESGIQ 346
Query: 381 GSTGQ 385
G GQ
Sbjct: 347 GFRGQ 351
Score = 57.4 bits (137), Expect = 4e-08
Identities = 48/150 (32%), Positives = 61/150 (40%), Gaps = 31/150 (20%)
Query: 290 SSAGSWNSGSSGP--GSTGNRNPGSSGTG--------------------GTATWKPGSSG 327
+SAGS+ G G GN P + GT G P SG
Sbjct: 179 NSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSG 238
Query: 328 PGSTGSW-----NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES----S 378
GS+ S SGSSG+GS G+ N GS GS+ + G S GS+G + S
Sbjct: 239 GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRG 298
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNP 408
SGS W S +GS + GSG + P
Sbjct: 299 DSGSESSWGSSTGSSSGNHGGSGGGNGHKP 328
Score = 51.2 bits (121), Expect = 3e-06
Identities = 41/130 (31%), Positives = 56/130 (43%), Gaps = 13/130 (10%)
Query: 288 NPSSAGSWNSGSSGPGSTGNRNPGSSGTGG-----TATWKPGSSGPGSTGSWNSGSSGTG 342
NP A G+ GP + G G+ G + G + P +GS S+ G
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 343 STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
+G+Q+ GS GS G N GSS GS+ S SS GS+G SG +S GS
Sbjct: 247 GSGSQS-GSSGSGSNGDNNNGSSSGGSS----SGSSSGGSSG---GSSGGSSGNSGGSRG 298
Query: 403 ARPNNPDWGT 412
+ WG+
Sbjct: 299 DSGSESSWGS 308
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/175 (26%), Positives = 68/175 (38%), Gaps = 14/175 (8%)
Query: 264 PGGNEI--TRGGSTSYGT--GSETESPRNPSSAGS-WNSGSSG--PGSTGNRNPGSSGTG 316
PG N T GG +G+ G + NP G+ W G G GS G NP + G
Sbjct: 136 PGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFG-MNPQGAPWG 194
Query: 317 GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
P + G + G+ G+ NQN G P +G+ S+ G +G
Sbjct: 195 QGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSG----- 249
Query: 377 SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S SGS+G + + S GS + + G S S G+R + +E
Sbjct: 250 -SQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSE 303
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 65.9 bits (159), Expect = 1e-10
Identities = 86/343 (25%), Positives = 142/343 (41%), Gaps = 36/343 (10%)
Query: 70 MKGLIDEVN---QDFTNRINKLKNSLFEYQKNN----KDSHSLTTNIMEILRGDFSSANN 122
++ ++DE+ D +I L L +KN+ KD +++T + + + ++A
Sbjct: 255 LRRVLDELTLTKADLEMQIESLTEELAYLKKNHEEEMKDLRNVSTGDVNV---EMNAAPG 311
Query: 123 RDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKR---LEVDIDIKIRS 179
D T ++ ++RS+ E L + +K+ A + + E+D +I+ S
Sbjct: 312 VDLT--QLLNNMRSQYEQLAEQN----------RKDAEAWFNEKSKELTTEIDNNIEQIS 359
Query: 180 CRGSCSRALAREVDLKDYEDQ-QKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFK 238
S L R V + E Q Q L+Q + L + R + L +++ + +
Sbjct: 360 SYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGRYCVQLSQIQAQISAL----E 415
Query: 239 SQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSS-AGSWNS 297
QLQ++ E + Q ++++ NEI S G GS R S G +
Sbjct: 416 EQLQQIRAETECQNTEYQQLLDIKIRLENEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGG 475
Query: 298 GSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGST 357
GSSG GS+G + G G + GSSG GS+G G S +G G + G GS+
Sbjct: 476 GSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSS 535
Query: 358 GTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS 400
G G S G +S G S SG + S GS
Sbjct: 536 GGGGGGYGGGSSGGGSSSGGGYGGG-----SSSGGHKSSSSGS 573
Score = 58.2 bits (139), Expect = 2e-08
Identities = 62/257 (24%), Positives = 106/257 (41%), Gaps = 23/257 (8%)
Query: 127 YNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKR---LEVDIDIKIRSCRGS 183
+N S++L + I+ ++ I L++NV+A ++++ L+ ++ + G
Sbjct: 340 FNEKSKELTTEIDNNIEQISSYKSEITELRRNVQALEIELQSQLALKQSLEASLAETEGR 399
Query: 184 -CSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQ 242
C + + + E+Q L+Q+ A+ + + Q L IK++ L+
Sbjct: 400 YCVQLSQIQAQISALEEQ---LQQIRAETECQNTEYQQLLDIKIR-------------LE 443
Query: 243 KVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESP---RNPSSAGSWNSGS 299
+++L + R GG+ G S G GS SS G + GS
Sbjct: 444 NEIQTYRSLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGS 503
Query: 300 SGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGT 359
SG GS+G G S +GG G G GS+G G G S G + G G + +
Sbjct: 504 SGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSS 563
Query: 360 WNPGSSERGSAGHWTSE 376
SS GS G +S+
Sbjct: 564 GGHKSSSSGSVGESSSK 580
Score = 45.1 bits (105), Expect = 2e-04
Identities = 42/122 (34%), Positives = 52/122 (42%), Gaps = 17/122 (13%)
Query: 290 SSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPG----------SSGPGSTGSWNSGSS 339
SS+ ++S SG G G G G GG ++ + SSG S GS++ GSS
Sbjct: 6 SSSKHYSSSRSGGGGGGG---GCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSS 62
Query: 340 GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPG 399
G G G + G G G G S RGS G + S GS G GSF S G
Sbjct: 63 GGGCFGGSSGGYGGLGGFG----GGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFG 118
Query: 400 SG 401
G
Sbjct: 119 GG 120
Score = 43.5 bits (101), Expect = 6e-04
Identities = 55/177 (31%), Positives = 65/177 (36%), Gaps = 29/177 (16%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGS 333
S Y + S R+ G G G G + R S G+ G SSG S GS
Sbjct: 2 SVRYSSSKHYSSSRSGGGGGGGGCGGGG-GVSSLRISSSKGSLGGGF----SSGGFSGGS 56
Query: 334 WNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSF 393
++ GSSG G G + G G G G S RGS G + S GS G GSF
Sbjct: 57 FSRGSSGGGCFGGSSGGYGGLGGFG----GGSFRGSYGSSSFGGSYGGSFG-----GGSF 107
Query: 394 RPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVT 450
S G G+ G F G G GD L +G EKVT
Sbjct: 108 GGGSFGGGSFGGGGFGGGGF---GGGFGGG------------FGGDGGLLSGNEKVT 149
Score = 43.1 bits (100), Expect = 8e-04
Identities = 41/111 (36%), Positives = 46/111 (41%), Gaps = 6/111 (5%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSG-SSGPGSTGNRNPGSSGTGGTATW 321
R GG GG G G S R SS GS G SSG S G+ + GSSG G
Sbjct: 15 RSGGG----GGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGS 70
Query: 322 KPGSSGPGSTGSWN-SGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAG 371
G G G G + GS G+ S G GS GS G + G G G
Sbjct: 71 SGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGG 121
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/93 (38%), Positives = 44/93 (47%), Gaps = 14/93 (15%)
Query: 266 GNEITRGGSTS--YGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
G + GGS+ YG GS + SS+G + GSSG G G GSSG G
Sbjct: 500 GGGSSGGGSSGGGYGGGS-SSGGHGGSSSGGYGGGSSG-GGGGGYGGGSSGGG------- 550
Query: 324 GSSGPGSTGSWNSG---SSGTGSTGNQNPGSPR 353
SSG G G +SG SS +GS G + PR
Sbjct: 551 SSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPR 583
Score = 29.6 bits (65), Expect = 9.0
Identities = 20/48 (41%), Positives = 22/48 (45%), Gaps = 2/48 (4%)
Query: 272 GGST--SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGG 317
GGS SYG+ S S GS+ GS G GS G G G GG
Sbjct: 82 GGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSFGGGGFGGGGFGG 129
>gi|148491080 trinucleotide repeat containing 6B isoform 2 [Homo
sapiens]
Length = 1723
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)
Query: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323
G+TS T + ++S R S GSW + + GP T G N G++G G +WK
Sbjct: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
Query: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366
G+S STGS W++ + TG + N P S G W P S+
Sbjct: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
Query: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
G W+ + + STG W ++ G P++ G+ A P WG +G+
Sbjct: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
Score = 53.1 bits (126), Expect = 8e-07
Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)
Query: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326
+G S TGS+ +S N S+ GSWN G S G N +SG +P S
Sbjct: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
Query: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378
G W N +S TG+ NQ G P P + G W SS GS
Sbjct: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
Query: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409
V G STG H ++GS + G + RP +PD
Sbjct: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
Score = 47.4 bits (111), Expect = 4e-05
Identities = 52/206 (25%), Positives = 73/206 (35%), Gaps = 40/206 (19%)
Query: 235 GNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGS 294
G+ SQ ++ W L+ + + G N+ S+++G G E + PSS
Sbjct: 667 GDAPSQSNQMKSGWGELSASTEWKDPKNTGGWNDYKNNNSSNWGGGRPDE--KTPSS--- 721
Query: 295 WNSG-SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPR 353
WN S G G R P W G +G G S+ S G
Sbjct: 722 WNENPSKDQGWGGGRQPNQG-------WSSGKNGWGEEVDQTKNSNWESSASKPVSGWGE 774
Query: 354 PGST--GTW-NPGSSERGSAGHWTS--ESSVSGSTGQ----WHSE--------------- 389
G GTW N G++ S G W S TG+ W+ +
Sbjct: 775 GGQNEIGTWGNGGNASLASKGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQP 834
Query: 390 --SGSFR-PDSPGSGNARPNNPDWGT 412
SGS+ P P GN RP+N W +
Sbjct: 835 EASGSWGGPPPPPPGNVRPSNSSWSS 860
Score = 37.0 bits (84), Expect = 0.056
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
G + GT + ++G W P + G + WK P +TG
Sbjct: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
Query: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390
WN + S N G P + +W NP + G ++ SG G W E
Sbjct: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
Query: 391 GSFRPDSPGSGNARPNNPDWG 411
+ + S ++P + WG
Sbjct: 754 DQTKNSNWESSASKPVS-GWG 773
Score = 35.8 bits (81), Expect = 0.13
Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)
Query: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336
TGS + + S G+W +S T + + +TW P G T N
Sbjct: 1417 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1476
Query: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392
S T PG P + W+ S+ S W ++ S S W S+ GS
Sbjct: 1477 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1533
Query: 393 FRP 395
RP
Sbjct: 1534 VRP 1536
Score = 34.7 bits (78), Expect = 0.28
Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)
Query: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335
S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N
Sbjct: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
Query: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365
S SS ST Q N P+ G+T + N P
Sbjct: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419
E + S ST +G + S GS G AR P+ D + + SGN
Sbjct: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
Score = 33.9 bits (76), Expect = 0.48
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)
Query: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298
++VPP ++ D + + P + + GG G T NP++A G+
Sbjct: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
Query: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334
SG ++ +TW G+S T S
Sbjct: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
Query: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391
++ SS +T N + + PGS + PGS+ +S+ SG + G W S+
Sbjct: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
Query: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424
+ S S + NN G + VSG + PG+
Sbjct: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
Score = 30.8 bits (68), Expect = 4.0
Identities = 38/164 (23%), Positives = 64/164 (39%), Gaps = 35/164 (21%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWN-------------------SGSSGPGST 305
GG + ++++G+G+ + + +P+ W+ + SS +T
Sbjct: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
Query: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSS 365
N + + G+ S+ PGST S + G GS Q+ S + G W
Sbjct: 217 DNNSASNPGS-------EKSTLPGSTTS----NKGKGSQ-CQSASSGNECNLGVWKSDPK 264
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSG--NARPNN 407
+ S S + + G W + SG R PGSG N PN+
Sbjct: 265 AK-SVQSSNSTTENNNGLGNWRNVSGQDR-IGPGSGFSNFNPNS 306
>gi|241982729 trinucleotide repeat containing 6B isoform 1 [Homo
sapiens]
Length = 1833
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/173 (28%), Positives = 75/173 (43%), Gaps = 32/173 (18%)
Query: 273 GSTSYGTGSETESP--RNPSSAGSWNSGSSGPGST----GNRNPGSSGTGGTA---TWKP 323
G+TS T + ++S R S GSW + + GP T G N G++G G +WK
Sbjct: 401 GNTSRSTDAPSQSTGDRKTGSVGSWGA-ARGPSGTDTVSGQSNSGNNGNNGKEREDSWK- 458
Query: 324 GSSGPGSTGS----WNSGSSGTGSTGNQNPGSPRPG------------STGTWN-PGSSE 366
G+S STGS W++ + TG + N P S G W P S+
Sbjct: 459 GASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGSD 518
Query: 367 RGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
G W+ + + STG W ++ G P++ G+ A P WG +G+
Sbjct: 519 ELKIGEWSGPNQPNSSTGAWDNQKGHPLPENQGNAQA----PCWGRSSSSTGS 567
Score = 53.1 bits (126), Expect = 8e-07
Identities = 50/152 (32%), Positives = 64/152 (42%), Gaps = 23/152 (15%)
Query: 271 RGGSTSYGTGSETES--PRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSS 326
+G S TGS+ +S N S+ GSWN G S G N +SG +P S
Sbjct: 458 KGASVQKSTGSKNDSWDNNNRSTGGSWNFGPQDSNDNKWGEGNKMTSGVSQGEWKQPTGS 517
Query: 327 GPGSTGSW---NSGSSGTGSTGNQNPGSPRPGSTGT-----WNPGSSERGSAGHWTSESS 378
G W N +S TG+ NQ G P P + G W SS GS
Sbjct: 518 DELKIGEWSGPNQPNSSTGAWDNQK-GHPLPENQGNAQAPCWGRSSSSTGS--------E 568
Query: 379 VSG-STGQWHSESGSFRPDSPGSGNARPNNPD 409
V G STG H ++GS + G + RP +PD
Sbjct: 569 VGGQSTGSNH-KAGSSDSHNSGRRSYRPTHPD 599
Score = 40.8 bits (94), Expect = 0.004
Identities = 34/127 (26%), Positives = 52/127 (40%), Gaps = 16/127 (12%)
Query: 265 GGNEITRGGSTSY-GTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-- 321
GG + +G S+ G G E + +N + S + SG G G G+ G GG A+
Sbjct: 734 GGRQPNQGWSSGKNGWGEEVDQTKNSNWESSASKPVSGWGEGGQNEIGTWGNGGNASLAS 793
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQN--------PGSPRPGSTGTWN-----PGSSERG 368
K G + +WN S Q+ P P+P ++G+W P + R
Sbjct: 794 KGGWEDCKRSPAWNETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP 853
Query: 369 SAGHWTS 375
S W+S
Sbjct: 854 SNSSWSS 860
Score = 37.0 bits (84), Expect = 0.056
Identities = 31/141 (21%), Positives = 49/141 (34%), Gaps = 13/141 (9%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
G + GT + ++G W P + G + WK P +TG
Sbjct: 644 GKSDKGTEGWESAATQTKNSGGWGDA---PSQSNQMKSGWGELSASTEWKD----PKNTG 696
Query: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTW--NPGSSERGSAGHWTSESSVSGSTGQWHSES 390
WN + S N G P + +W NP + G ++ SG G W E
Sbjct: 697 GWNDYKNNNSS--NWGGGRPDEKTPSSWNENPSKDQGWGGGRQPNQGWSSGKNG-WGEEV 753
Query: 391 GSFRPDSPGSGNARPNNPDWG 411
+ + S ++P + WG
Sbjct: 754 DQTKNSNWESSASKPVS-GWG 773
Score = 35.8 bits (81), Expect = 0.13
Identities = 31/123 (25%), Positives = 44/123 (35%), Gaps = 9/123 (7%)
Query: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNS-- 336
TGS + + S G+W +S T + + +TW P G T N
Sbjct: 1527 TGSNSSLNTSLPSPGAWPYSASDNSFTNVHSTSAKFPDYKSTWSPDPIGHNPTHLSNKMW 1586
Query: 337 ----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392
S T PG P + W+ S+ S W ++ S S W S+ GS
Sbjct: 1587 KNHISSRNTTPLPRPPPGLTNPKPSSPWS--STAPRSVRGWGTQDSRLASASTW-SDGGS 1643
Query: 393 FRP 395
RP
Sbjct: 1644 VRP 1646
Score = 34.7 bits (78), Expect = 0.28
Identities = 46/176 (26%), Positives = 65/176 (36%), Gaps = 37/176 (21%)
Query: 281 SETESPRNPSSAGSWNSGSS----GPGST-GNRNPGSSGTGGTATWKPGSSGPGSTGSWN 335
S + N + G+W + S GPGS N NP S+ + A + G+S G+ + N
Sbjct: 270 SSNSTTENNNGLGNWRNVSGQDRIGPGSGFSNFNPNSNPSAWPALVQEGTSRKGALETDN 329
Query: 336 SGSSGTGSTGNQ---------------------------NPGSPRPGSTGTWN---PGSS 365
S SS ST Q N P+ G+T + N P
Sbjct: 330 SNSSAQVSTVGQTSREQQSKMENAGVNFVVSGREQAQIHNTDGPKNGNTNSLNLSSPNPM 389
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGS-GNAR-PNNPDWGTFEEVSGN 419
E + S ST +G + S GS G AR P+ D + + SGN
Sbjct: 390 ENKGMPFGMGLGNTSRSTDAPSQSTGDRKTGSVGSWGAARGPSGTDTVSGQSNSGN 445
Score = 33.9 bits (76), Expect = 0.48
Identities = 47/215 (21%), Positives = 78/215 (36%), Gaps = 38/215 (17%)
Query: 242 QKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSA---GSWNSG 298
++VPP ++ D + + P + + GG G T NP++A G+
Sbjct: 89 REVPPRFRCQQDHKVLLKRGQPPPPSCMLLGGGA--GPPPCTAPGANPNNAQVTGALLQS 146
Query: 299 SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST------------------------GSW 334
SG ++ +TW G+S T S
Sbjct: 147 ESGTAPDSTLGGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASK 206
Query: 335 NSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG---STGQWHSESG 391
++ SS +T N + + PGS + PGS+ +S+ SG + G W S+
Sbjct: 207 DTESSSENTTDNNS--ASNPGSEKSTLPGSTTSNKGKGSQCQSASSGNECNLGVWKSDPK 264
Query: 392 SFRPDSPGSGNARPNNPDWGTFEEVSG--NVSPGT 424
+ S S + NN G + VSG + PG+
Sbjct: 265 AKSVQS--SNSTTENNNGLGNWRNVSGQDRIGPGS 297
Score = 32.7 bits (73), Expect = 1.1
Identities = 41/168 (24%), Positives = 58/168 (34%), Gaps = 32/168 (19%)
Query: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGT-GGTATWKPGSSGPGSTGSWNSGSSGTG 342
E+ R P+S + P P +SG+ GG PG+ P S SW+SG
Sbjct: 808 ETGRQPNSWNKQHQQQQPPQQPPPPQPEASGSWGGPPPPPPGNVRP-SNSSWSSGPQPAT 866
Query: 343 STGNQNPG--SPRPGS----------TGTW-NPGSSERGSAGHWTSESS----------- 378
+ G P P S T W +P S + W S
Sbjct: 867 PKDEEPSGWEEPSPQSISRKMDIDDGTSAWGDPNSYNYKNVNLWDKNSQGGPAPREPNLP 926
Query: 379 ---VSGSTGQWHSESGSFRPDSPGSGNARPN--NPDWGTFEEVSGNVS 421
S S W S+S PD+ S PN +P WG ++ + +
Sbjct: 927 TPMTSKSASVW-SKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTT 973
Score = 32.7 bits (73), Expect = 1.1
Identities = 32/123 (26%), Positives = 50/123 (40%), Gaps = 21/123 (17%)
Query: 285 SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSSGPGSTGSWNSGSS--GT 341
+PR P+ S S+ S +++ + GT+ W +P S PG ++G+S G
Sbjct: 919 APREPNLPTPMTSKSA---SVWSKSTPPAPDNGTSAWGEPNESSPGWGEMDDTGASTTGW 975
Query: 342 GSTGNQNPGSPRPGS--------------TGTWNPGSSERGSAGHWTSESSVSGSTGQWH 387
G+T P + +P S TG +P E G W + S GS +
Sbjct: 976 GNTPANAPNAMKPNSKSMQDGWGESDGPVTGARHPSWEEEEDGGVWNTTGS-QGSASSHN 1034
Query: 388 SES 390
S S
Sbjct: 1035 SAS 1037
Score = 30.8 bits (68), Expect = 4.0
Identities = 38/164 (23%), Positives = 64/164 (39%), Gaps = 35/164 (21%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWN-------------------SGSSGPGST 305
GG + ++++G+G+ + + +P+ W+ + SS +T
Sbjct: 157 GGAAASNYANSTWGSGASSNNGTSPNPIHIWDKVIVDGSDMEEWPCIASKDTESSSENTT 216
Query: 306 GNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSS 365
N + + G+ S+ PGST S + G GS Q+ S + G W
Sbjct: 217 DNNSASNPGS-------EKSTLPGSTTS----NKGKGSQ-CQSASSGNECNLGVWKSDPK 264
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSG--NARPNN 407
+ S S + + G W + SG R PGSG N PN+
Sbjct: 265 AK-SVQSSNSTTENNNGLGNWRNVSGQDR-IGPGSGFSNFNPNS 306
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 61.2 bits (147), Expect = 3e-09
Identities = 92/396 (23%), Positives = 143/396 (36%), Gaps = 62/396 (15%)
Query: 265 GGNEITRGGSTSYGTGS-------ETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGG 317
G G +GTGS + ES SS G SGSS G S T G
Sbjct: 1042 GSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSG 1101
Query: 318 TATWKPGSSGPGSTGSWNSGS----------SGTG---------------STGNQNPGSP 352
+PGS G + SGS SGTG S G GS
Sbjct: 1102 FGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSS 1161
Query: 353 RPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG-SFRPDSPGSGNARPNNPDWG 411
+ G GS S G S S S+GQ S+SG S GSG+ + G
Sbjct: 1162 QSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQG 1221
Query: 412 TFEEV-SGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVI 470
++V SG+ G + H + + T++ + + + S T R S S+ V
Sbjct: 1222 ESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVH 1281
Query: 471 GPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFP 530
H+ E + ++ GS P++ S + G H + + G++
Sbjct: 1282 SKVSHRH--SEHIHTQAGSHYPKSG-----STVRRRQGTTHGQRGDTTRHGHSGHGQS-- 1332
Query: 531 GFFSPMLGEFVSETESRGSESGIFTNTKESSSH-HPGIAEFPSRGKSSSYSKQFTSSTSY 589
++T SR S F+++ + S H G++ P + ++S+ + + +
Sbjct: 1333 -----------TQTGSRTSGRQRFSHSDATDSEVHSGVSHRP-HSQEQTHSQ---AGSQH 1377
Query: 590 NRGDSTFESK---SYKMADEAGSEADHEGTHSTKRG 622
+ST + +Y EA ST+RG
Sbjct: 1378 GESESTVHERHETTYGQTGEATGHGHSGHGQSTQRG 1413
Score = 53.9 bits (128), Expect = 4e-07
Identities = 44/141 (31%), Positives = 61/141 (43%), Gaps = 5/141 (3%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPG 324
G +E G S+ +G S N GS +S SSG G G+ + ++G G +
Sbjct: 975 GQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQ 1034
Query: 325 SSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGS--SERGSAGHWTSESSVSGS 382
SG G GS + SSG G G GS + G + S S G G +S+SS G
Sbjct: 1035 YSGFGQHGSGSDQSSGFGQHGT---GSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQ 1091
Query: 383 TGQWHSESGSFRPDSPGSGNA 403
G ++ F PGSG +
Sbjct: 1092 HGSNSGQTSGFGQHRPGSGQS 1112
Score = 53.1 bits (126), Expect = 8e-07
Identities = 93/367 (25%), Positives = 136/367 (37%), Gaps = 40/367 (10%)
Query: 265 GGNEITRGGSTSYGT-GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
G +E T S Y GS + GS + SSG G G+ + SSG G +
Sbjct: 454 GQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSG 513
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTS-ESSVSGS 382
SSG G GS + SSG G Q+ R S G GSS+ G + S E+S G
Sbjct: 514 QSSGFGQHGSVSGQSSGFG----QHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQ 569
Query: 383 TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL 442
G +S F GSG + +G SG S G E
Sbjct: 570 HGLGSGQSTGFGQYGSGSG----QSSGFGQHGSGSGQSS--------------GFGQHES 611
Query: 443 RTGKEKV---TSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGT 499
R+G+ +SGS+ ++ + + G G ++ + GS ++ G
Sbjct: 612 RSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGS-SQSTGFGQYGSGSGQSSGFGQ 670
Query: 500 -LSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTK 558
+SG G GF +H + +S G+ GF S + S G SG F +
Sbjct: 671 HVSGSGQSSGF-GQHESRSGH---SSYGQ--HGFGSSQSSGYGQHGSSSGQTSG-FGQHE 723
Query: 559 ESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESK----SYKMADEAGSEADHE 614
SS + S SS Q S + + G ES+ SY S++
Sbjct: 724 LSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGY 783
Query: 615 GTHSTKR 621
G H +++
Sbjct: 784 GQHGSRQ 790
Score = 50.8 bits (120), Expect = 4e-06
Identities = 83/370 (22%), Positives = 125/370 (33%), Gaps = 36/370 (9%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
GS Y + ES + SS G SGSS G S T G + GS G
Sbjct: 903 GSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFG 962
Query: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGS 392
SGS + G GS + G SS+ H + S SG + + GS
Sbjct: 963 QHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG-----YGQHGS 1017
Query: 393 FRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVT-- 450
+ G G R ++ + F + + H S G + + + +
Sbjct: 1018 SSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYG 1077
Query: 451 ---SGSTTTTRRSCSKTVTKTVIGPDGHKEVT-KEVVTSEDGSDCPEAMDLGTL-SGIGT 505
SGS+ ++ + + G H+ + + + GS ++ G SG G
Sbjct: 1078 QHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGK 1137
Query: 506 LDGF-RHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHH 564
GF +H + + + TG S++ G T H
Sbjct: 1138 SSGFAQHEYRSGQSSYGQHGTGS--------------SQSSGCGQHESGSGPTTSFGQHV 1183
Query: 565 PGIAEFPSRGKSSSYSKQFTSSTSY--NRGDSTFESKSYKMADEAGS------EADHEGT 616
G F S G+ S S Q T Y G ST + E+GS E H T
Sbjct: 1184 SGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQT 1243
Query: 617 HSTKRGHAKS 626
+T R H++S
Sbjct: 1244 INTTR-HSQS 1252
Score = 48.1 bits (113), Expect = 2e-05
Identities = 92/371 (24%), Positives = 128/371 (34%), Gaps = 28/371 (7%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGS 325
G + G TS G G S SS G SGS G GS + G +
Sbjct: 707 GQHGSSSGQTS-GFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHE-SR 764
Query: 326 SGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQ 385
SG S G +SGSS + G GS + G GSS+ G + S S S GQ
Sbjct: 765 SGQSSYGQHSSGSSQSSGYGQH--GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQ 822
Query: 386 WHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTS-----KGDK 440
SGS + G +R + +G + SG+ ++ + TS +
Sbjct: 823 --HGSGSGQSSGFGQHESRSHQSSYG--QHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSS 878
Query: 441 ELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL 500
+G + SGS ++ T + G H+ + + + GS ++ G
Sbjct: 879 GQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQH 938
Query: 501 -SGIGTLDGF-RHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTK 558
S G GF +HR S+G G S F G SG
Sbjct: 939 GSSSGQTFGFGQHRSG------SGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGF--GQH 990
Query: 559 ESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS--YKMADEAGSEADHE-- 614
ES S + S SS Q SS+ G S S Y + GS +D
Sbjct: 991 ESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSG 1050
Query: 615 -GTHSTKRGHA 624
G H T G +
Sbjct: 1051 FGQHGTGSGQS 1061
Score = 48.1 bits (113), Expect = 2e-05
Identities = 93/422 (22%), Positives = 143/422 (33%), Gaps = 68/422 (16%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG-----G 317
RPG + + G G+G + ++ S G + + +G + G GTG G
Sbjct: 1106 RPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSG 1165
Query: 318 TATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES 377
+ GS S G SGS S+G S + G + GS + G S+
Sbjct: 1166 CGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQ 1225
Query: 378 SVSGST---------GQW-----HSESGSFRPDSPGS--GNARPNNPDWGTFEEVSGNVS 421
SGST GQ HS+SG + GS R ++ + EV VS
Sbjct: 1226 VESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVS 1285
Query: 422 PGTRREYHTEKLVTSKGDKELRTGK-------------------------EKVTSGSTTT 456
H+E + T G ++G + +GS T+
Sbjct: 1286 -----HRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTS 1340
Query: 457 TRR--SCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDL------GTLSGIGTLDG 508
R+ S S V H+ ++E S+ GS E+ T G G
Sbjct: 1341 GRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATG 1400
Query: 509 FRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSH-HPGI 567
H ++ + +TG+ G E V S +S T+ + S H G
Sbjct: 1401 HGHSGHGQSTQRGSRTTGRRGSGHSESSDSE-VHSGGSHRPQSQEQTHGQAGSQHGESGS 1459
Query: 568 AEFPSRGKSSSYSKQFTSSTSYN------RGDSTFESKSYKMADEAGSEADHEGTHSTKR 621
G + + T Y+ RG ST + ++ + SE G+H T
Sbjct: 1460 TVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSH-THS 1518
Query: 622 GH 623
GH
Sbjct: 1519 GH 1520
Score = 47.8 bits (112), Expect = 3e-05
Identities = 86/376 (22%), Positives = 127/376 (33%), Gaps = 27/376 (7%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSG---SSGPGSTGNRNPGSSGTGGTATW 321
G + G S G G ES SS G G SSG G G+ + +SG G
Sbjct: 667 GFGQHVSGSGQSSGFGQH-ESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELS 725
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGN---------QNPGSPRPGSTGTWNPGSSERGSAG- 371
SS G GS + SSG G G+ Q+ S G + GSS+ G
Sbjct: 726 SGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQ 785
Query: 372 HWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
H + ++S G G S+S F GSG + + SG +R +
Sbjct: 786 HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSY 845
Query: 432 KLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDC 491
S + G+ +SG T+ + S + + G G + +
Sbjct: 846 GQHGSGSSQSSGYGQHGSSSGQTSGFGQHRSSSGQYSGFGQHGSG-------SGQSSGFG 898
Query: 492 PEAMDLGTLSGIGTLDGFRHRHP-DEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSE 550
G SG G + H+ + + S+G G S F G
Sbjct: 899 QHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQS 958
Query: 551 SGIFTNTKESSSHHPGIAEFPS-RGKSSSYSKQFTSSTSYN---RGDSTFESKSYKMADE 606
SG F S G + S GKSS + + + S+ N G + +S Y
Sbjct: 959 SG-FGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGS 1017
Query: 607 AGSEADHEGTHSTKRG 622
+ + G H + G
Sbjct: 1018 SSGQTTGFGQHRSSSG 1033
Score = 47.4 bits (111), Expect = 4e-05
Identities = 80/342 (23%), Positives = 118/342 (34%), Gaps = 44/342 (12%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGS 325
G + G T+ G G S S G SGS G GS + G ++ S
Sbjct: 1013 GQHGSSSGQTT-GFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRS 1071
Query: 326 --SGPGSTGSWNSGSSGTGSTGN----------QNPGSPRPGSTGTWNPGSSERGSAGHW 373
S G GS +S SSG G G+ PGS + G + GS + G
Sbjct: 1072 RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQH 1131
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKL 433
S + S Q SG G+G+++ + G E SG P T H
Sbjct: 1132 GSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSG--CGQHESGSG---PTTSFGQH---- 1182
Query: 434 VTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPE 493
S D +G+ SG +T + S + T +G ++V E GS
Sbjct: 1183 -VSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQGESQQV-------ESGSTVHG 1234
Query: 494 AMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGI 553
+ T G T++ RH + T S + ++S S+S +
Sbjct: 1235 RQE--TTHG-QTINTTRHSQSGQGQSTQTGS-----------RVTRRRRSSQSENSDSEV 1280
Query: 554 FTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDST 595
+ S H KS S ++ +T RGD+T
Sbjct: 1281 HSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTT 1322
Score = 47.0 bits (110), Expect = 5e-05
Identities = 84/376 (22%), Positives = 132/376 (35%), Gaps = 25/376 (6%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
G S+ +G + GS +S SSG G G+R G G GS
Sbjct: 526 GQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGL-----GSGQSTGF 580
Query: 332 GSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESG 391
G + SGS + G GS + G + S + S G +S SS S GQ H
Sbjct: 581 GQYGSGSGQSSGFGQHGSGSGQSSGFGQ-HESRSGQSSYGQHSSGSSQSSGYGQ-HGSRQ 638
Query: 392 SFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTS 451
+ GSG+++ + +G + SG S G + + G E R+G
Sbjct: 639 TSGFGQHGSGSSQ--STGFGQYGSGSGQ-SSGFGQHVSGSGQSSGFGQHESRSGHSSYGQ 695
Query: 452 ---GSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVT-SEDGSDCPEAMDLGTL-SGIGTL 506
GS+ ++ + + G H+ + + + + GS ++ G SG G
Sbjct: 696 HGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQS 755
Query: 507 DGF-RHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHP 565
GF +H + + S+G + + S GS S T + S
Sbjct: 756 SGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSG 815
Query: 566 GIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAK 625
A F G S S+ + + +S SY S++ G H + G
Sbjct: 816 QSAGFGQHGSGSG------QSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTS 869
Query: 626 SRPVRGIHTSPLGKPS 641
G H S G+ S
Sbjct: 870 G---FGQHRSSSGQYS 882
Score = 43.9 bits (102), Expect = 5e-04
Identities = 87/373 (23%), Positives = 133/373 (35%), Gaps = 35/373 (9%)
Query: 268 EITRGGSTSYG----TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS-GTGGTATWK 322
+ T G S+G TGS T R S S S S GP + + G + G G+ +
Sbjct: 1928 DTTEHGHPSHGQTIQTGSRTTGRRG--SGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPE 1985
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPG-SPRPGS--TGTWNPGSSERG-SAGH----WT 374
GSS G+ + ++ T G+ G S + GS TG G SE S GH T
Sbjct: 1986 SGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHT 2045
Query: 375 SESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLV 434
G G H ESGS + G+ + + + + G+R
Sbjct: 2046 HSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGH 2105
Query: 435 TSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEA 494
+ D E+ +G SG T RS + G G T T +
Sbjct: 2106 SESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQG----TIHGQTGDTTRHGQSG 2161
Query: 495 MDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIF 554
T +G T R H + + D+ + P G S+ SR +SG
Sbjct: 2162 HGQSTQTGSRTTGRQRSSHSESS---DSEVHSEASP----THSGHTHSQAGSRHGQSGSS 2214
Query: 555 TNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHE 614
+ ++ ++H G +R Y + S RG T + ++ + SE
Sbjct: 2215 GHGRQGTTH--GQTGDTTRHAHYGYGQ------STQRGSRTTGRRGSGHSESSDSEVHSW 2266
Query: 615 GTHSTKRGHAKSR 627
G+H T GH + +
Sbjct: 2267 GSH-THSGHIQGQ 2278
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/351 (23%), Positives = 119/351 (33%), Gaps = 67/351 (19%)
Query: 275 TSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP------ 328
T+YG +T +G S G +TG R G S + + GS P
Sbjct: 1390 TTYG---QTGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQT 1446
Query: 329 --------GSTGSWNSGSSGT--GSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESS 378
G +GS G GT G TG+ + T GSS G G SESS
Sbjct: 1447 HGQAGSQHGESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQR-GSSTTGRRGSGHSESS 1505
Query: 379 VS-----GS---TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
S GS +G H +SGS +S + R G TR Y
Sbjct: 1506 DSEVHSGGSHTHSGHTHGQSGSQHGESESIIHDR--------HRITHGQTGDTTRHSYSG 1557
Query: 431 EKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSD 490
+ T G + TG++ R S S++ V H+ ++E + GS
Sbjct: 1558 HEQTTQTGSR--TTGRQ----------RTSHSESTDSEVHSGGSHRPHSREHTYGQAGSQ 1605
Query: 491 CPEAMDL-----GTLSG-IGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSET 544
E GT G IG G H ++ + +TG+ +
Sbjct: 1606 HEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTTGRQ-------------RSS 1652
Query: 545 ESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDST 595
S S+S + + + + H G+S S + +T GD+T
Sbjct: 1653 HSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDTT 1703
Score = 41.6 bits (96), Expect = 0.002
Identities = 91/408 (22%), Positives = 139/408 (34%), Gaps = 69/408 (16%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNP--GSSGTGGTA 319
ER G ++ G TS + T+S GS SGS G +G R+ G S + G
Sbjct: 233 ERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGS---GDSGRRSHACGYSNSSGCG 289
Query: 320 TWKPGSS--------GPGSTGSWNSGSSGTGSTGNQNPGSPRPGS-TGTWNPGS------ 364
+ SS G G+ S+ +G G Q G G +G P S
Sbjct: 290 RPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCVSGGQPSGCGQPESNPCSQS 349
Query: 365 -SERG-----------SAGHWTSESSVSGSTGQWHS------ESGSFRPDSPGSGNARPN 406
S+RG G W + SS S GQ+ S +G S G + +
Sbjct: 350 YSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSS 409
Query: 407 NPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVT 466
+ ++ ++ S T E H L S G ++ G + +T+ +S
Sbjct: 410 SNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQS------ 463
Query: 467 KTVIGPDGHKEVT-KEVVTSEDGSDCPEAMDLGTL-SGIGTLDGFRHR---HPDEAAFFD 521
+G D H + K + GS ++ G SG G GF + F
Sbjct: 464 ---LGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQ 520
Query: 522 TASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSR-----GKS 576
S GF + ESR +S + SS G ++ SR G+
Sbjct: 521 HGSVSGQSSGF---------GQHESRSRQSS-YGQHGSGSSQSSGYGQYGSRETSGFGQH 570
Query: 577 SSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHA 624
S Q T Y G +S + ++ G H ++ G +
Sbjct: 571 GLGSGQSTGFGQYGSGSG--QSSGFGQHGSGSGQSSGFGQHESRSGQS 616
Score = 39.3 bits (90), Expect = 0.011
Identities = 46/213 (21%), Positives = 71/213 (33%), Gaps = 15/213 (7%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
R G + + G G+G + ++ S +G + + N G G+G + +
Sbjct: 952 RSGSGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSG 1011
Query: 323 PGSSGPGS-----TGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES 377
G G S G S S G GS + G GS + G + S S
Sbjct: 1012 YGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRS 1071
Query: 378 SVS--GSTGQWHSES------GSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYH 429
S G G S+S GS + G G RP + F + + H
Sbjct: 1072 RQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQH 1131
Query: 430 TEKLVTSKG--DKELRTGKEKVTSGSTTTTRRS 460
S G E R+G+ T +++ S
Sbjct: 1132 GSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSS 1164
Score = 38.5 bits (88), Expect = 0.019
Identities = 43/153 (28%), Positives = 60/153 (39%), Gaps = 11/153 (7%)
Query: 262 ERPGGNEITRGGSTSYG-TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
ER G G +T + +G + R +AG SG S S + G S T T
Sbjct: 2067 ERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHS-ESSDSEVHSGVSHTHSGHT 2125
Query: 321 WKPGSSGPGSTGSWNSGSSGT--GSTGNQ-------NPGSPRPGSTGTWNPGSSERGSAG 371
+ S G +GS G GT G TG+ + S + GS T SS S+
Sbjct: 2126 YGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQRSSHSESSD 2185
Query: 372 HWTSESSVSGSTGQWHSESGSFRPDSPGSGNAR 404
+ +G HS++GS S SG+ R
Sbjct: 2186 SEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGR 2218
Score = 38.5 bits (88), Expect = 0.019
Identities = 40/147 (27%), Positives = 60/147 (40%), Gaps = 21/147 (14%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGS-----SGPGSTGNRNPGSSGTGGTA 319
G + T+ GS + G S + S SW S + G + R PGS+ G
Sbjct: 2236 GYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLE 2295
Query: 320 --------TWKPGSSGPG---STGSWNSGSS--GTGSTGNQNPGSPRPGSTGTWNPGSSE 366
T + G SG G TGS +S +S + S+ Q GS + G++ P +
Sbjct: 2296 TTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSSQVWKHGSYGPAEYD 2355
Query: 367 RGSAGHWT---SESSVSGSTGQWHSES 390
G G+ S S+S S W ++S
Sbjct: 2356 YGHTGYGPSGGSRKSISNSHLSWSTDS 2382
Score = 35.8 bits (81), Expect = 0.13
Identities = 96/448 (21%), Positives = 146/448 (32%), Gaps = 89/448 (19%)
Query: 262 ERPGGNEITRGGSTSY-------------GTGSETESPRNPSSAGSWNSGSSGPGSTGNR 308
+RP T G + S T +T S +G S SG +TG R
Sbjct: 1817 QRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRR 1876
Query: 309 NPGSSGTGGTATWKPGS-SGPGSTGSWNSGSSGT-------------GSTGNQNP-GSPR 353
G S + + GS + G T S G G TG+ G P
Sbjct: 1877 RSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPS 1936
Query: 354 PGSTGTWNPGSSERGSAGH--WTSESSVSG----STGQWHSESGSFRPDSPGSGNARPNN 407
G T ++ R +GH ++ SG +G H ++GS P+S S + R
Sbjct: 1937 HGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGT 1996
Query: 408 PDWGTFEEV------------SGNVSPGTRREYHTE---------KLVTSKGDKELRTGK 446
T + G+ + G R H+E T G + G
Sbjct: 1997 THGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGS 2056
Query: 447 EKVTSGSTTTTRRSCS--KTVTKTVIGPDGHKEVTK--EVVTSEDGSDCPEAMDLGTLSG 502
+ SGS+ R + +T T GH + T+ GS E+ D SG
Sbjct: 2057 QHGESGSSVHERHGTTHGQTGDTTRHAHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSG 2116
Query: 503 IG------TLDGFRHRHPDEAAFF------------DTASTGKTFPGFFSPMLGEFVSET 544
+ T R +H + + DT G++ G +
Sbjct: 2117 VSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGDTTRHGQSGHGQSTQTGSRTTGRQ 2176
Query: 545 ESRGSESGIFTNTKESSSHHPGIAEFPS---RGKSSSYSKQFTSSTSYNRGDSTFESKSY 601
S SES E+S H G + G+S S +T GD+T
Sbjct: 2177 RSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTT------ 2230
Query: 602 KMADEAGSEADHEGTHSTKR---GHAKS 626
+ A ++ G+ +T R GH++S
Sbjct: 2231 RHAHYGYGQSTQRGSRTTGRRGSGHSES 2258
Score = 33.5 bits (75), Expect = 0.62
Identities = 95/392 (24%), Positives = 133/392 (33%), Gaps = 91/392 (23%)
Query: 272 GGSTSYGTGSETESPRNPS-SAGSWNSGSSG----PGSTGNRNPGSSGTG---------- 316
G S TGS T R+ S S + G SG P S G+ + G +G+
Sbjct: 1784 GHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPHSRGHTH-GQAGSQHGESESIVDE 1842
Query: 317 --GTATWKPG-SSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
GT + G +SG +G S SG+ +TG + G SE S G
Sbjct: 1843 RHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRRSGHS--------ESSDSEVHSGGSH 1894
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVS-GNVSPGTRREYHTEK 432
T +G HS++ S +S + + R T + G+ S G
Sbjct: 1895 T-------HSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSHG--------- 1938
Query: 433 LVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCP 492
+ + +GS TT RR + GP G + GS P
Sbjct: 1939 --------------QTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGHTHGQAGSHYP 1984
Query: 493 EAMDL-----GTLSGIGTLDGFRHRHPDEAAFFDTAS--TGKTFPGF--FSPMLGEF-VS 542
E+ GT G T D RH H S TG+ G +S G VS
Sbjct: 1985 ESGSSVHERHGTTHG-QTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVS 2043
Query: 543 ETE---------SRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSY--SKQFTSSTSYNR 591
T S+ ESG + + ++H G +R S + S Q S T+ R
Sbjct: 2044 HTHSGHAHGQAGSQHGESGSSVHERHGTTH--GQTGDTTRHAHSGHGQSTQRGSRTAGRR 2101
Query: 592 GDSTFESKSYKMADEAGSEADHEGTHSTKRGH 623
G ES ++ H G T GH
Sbjct: 2102 GSGHSESSDSEV---------HSGVSHTHSGH 2124
Score = 31.2 bits (69), Expect = 3.1
Identities = 27/96 (28%), Positives = 39/96 (40%), Gaps = 8/96 (8%)
Query: 258 RMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGG 317
R+E + TR G + YG ++T S S A + S SS G+ G+ G
Sbjct: 2293 RLETTHGQTGDTTRHGHSGYGQSTQTGS--RSSRASHFQSHSSERQRHGSSQVWKHGSYG 2350
Query: 318 TATWKPGSSGPGSTGSWNSGSS------GTGSTGNQ 347
A + G +G G +G S T ST N+
Sbjct: 2351 PAEYDYGHTGYGPSGGSRKSISNSHLSWSTDSTANK 2386
Score = 30.4 bits (67), Expect = 5.3
Identities = 32/135 (23%), Positives = 48/135 (35%), Gaps = 6/135 (4%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGS 333
S S +G E ES S + SW G S G G + + G +GS
Sbjct: 214 SPSRESGEEYESG---SGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGS 270
Query: 334 WNSG--SSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG-STGQWHSES 390
+SG S G + + G P+ S+ + +G+ + SG GQ H
Sbjct: 271 GDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCV 330
Query: 391 GSFRPDSPGSGNARP 405
+P G + P
Sbjct: 331 SGGQPSGCGQPESNP 345
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 58.9 bits (141), Expect = 1e-08
Identities = 101/419 (24%), Positives = 152/419 (36%), Gaps = 61/419 (14%)
Query: 264 PGGNEITRGGSTSYGTGSE-TESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
P G + STS T + T + + S+ S + +S P S+G+R + GTAT
Sbjct: 751 PEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPASSGSRTTSA----GTAT-- 804
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
P SSG ++G+ SGS G ++G S P ++E SA S ++ S
Sbjct: 805 PSSSG--ASGTTPSGSEGISTSGETTRFSSNPSRDSHTTQSTTELLSAS--ASHGAIPVS 860
Query: 383 TGQWHS-ESGSFRPD-SPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDK 440
TG S G+F P S S RP T S + R T++ TS+G
Sbjct: 861 TGMASSIVPGTFHPTLSEASTAGRPTGQSSPTSPSASPQETAAISRMAQTQRTRTSRGSD 920
Query: 441 ELRTGKEKVTSGST--------TTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCP 492
+ + + ST T+T + +T T T+ K T ++++
Sbjct: 921 TISLASQATDTFSTVPPTPPSITSTGLTSPQTETHTLSPSGSGKTFTTALISNATPLPVT 980
Query: 493 EAMDLGT----------LSGIGTLDGFRHRHPDEAAFFDTASTGKTFP-----------G 531
A T S + T H P + STG T P G
Sbjct: 981 YASSASTGHTTPLHVTDASSVST----GHATPLPVTSPSSVSTGHTTPLPVTDTSSESTG 1036
Query: 532 FFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTS-STSYN 590
+P+ S + S T+T +S+ H + P SS+ + T +
Sbjct: 1037 HVTPLPVTSFSSASTGDSTPLPVTDTSSASTGH--VTPLPVTSLSSASTGDTTPLPVTDT 1094
Query: 591 RGDSTFESKSYKMADEAGSEADH------EGTHSTKRGHAKSRPVRGI------HTSPL 637
ST + S + D + H T S GHA S PV HT+PL
Sbjct: 1095 SSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPL 1153
Score = 40.4 bits (93), Expect = 0.005
Identities = 83/412 (20%), Positives = 138/412 (33%), Gaps = 60/412 (14%)
Query: 268 EITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRN---PGSSGTGGTATWKPG 324
+I+ T G+ET P S++ G S T + P S + G TW
Sbjct: 446 KISTAFHTQQSEGAETTG--RPHERSSFSPGVSQEIFTLHETTTWPSSFSSKGHTTWSQT 503
Query: 325 SSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTS--ESSVSGS 382
STG+ +G STG P + H T+ +++ +G+
Sbjct: 504 ELPSTSTGAATRLVTGNPSTGTAGTIPRVPSKVSAIGEPGEPTTYSSHSTTLPKTTGAGA 563
Query: 383 TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGT--RREYHTEKLVTSKGDK 440
QW E+G+ +G A ++P + + + SP + + HT + +T+
Sbjct: 564 QTQWTQETGT-------TGEALLSSPSYSVTQMIKTATSPSSSPMLDRHTSQQITTAPST 616
Query: 441 ELRT-------------------GKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKE 481
T + T+ + TTR T TKTV P +
Sbjct: 617 NHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSVSPMTDTKTVTTPGSSFTASGH 676
Query: 482 VVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFV 541
+ D P T + T DG + P A +S T P G +
Sbjct: 677 SPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQAAPSSHDAT----LGPSGGTSL 732
Query: 542 SET----------ESRGSESGIFTNTKESSS--------HHPGIAEFPSRGKSSSYSKQF 583
S+T + G G +T+ S+S H + G++ +
Sbjct: 733 SKTGALTLANSVVSTPGGPEGQWTSASASTSPDTAAAMTHTHQAESTEASGQTQTSEPAS 792
Query: 584 TSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTS 635
+ S + + G +T S +GSE +T+ S P R HT+
Sbjct: 793 SGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTR---FSSNPSRDSHTT 841
Score = 39.7 bits (91), Expect = 0.009
Identities = 78/352 (22%), Positives = 128/352 (36%), Gaps = 27/352 (7%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSG 314
P L+R +IT ST++ T T + S A S + P +T S
Sbjct: 596 PSSSPMLDRHTSQQITTAPSTNHSTIHSTSTSPQESPAVSQRGHTQAPQTTQESQTTRSV 655
Query: 315 TGGTATWKPGSSGPGSTGSWNSGS----SGTGSTGNQNPGSPRPGSTGTWNPGSSERGSA 370
+ T T + G T S +S S + +P P G + A
Sbjct: 656 SPMTDTKTVTTPGSSFTASGHSPSEIVPQDAPTISAATTFAPAPTGDGHTTQAPTTALQA 715
Query: 371 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREY-H 429
+ ++++ S G S++G+ S + P P+ G + S + SP T H
Sbjct: 716 APSSHDATLGPSGGTSLSKTGAL--TLANSVVSTPGGPE-GQWTSASASTSPDTAAAMTH 772
Query: 430 TEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVT-KTVIGPDGHKEVTKEVVTSEDG 488
T + +++ + +T E +SGS TT+ + + + + + P G + ++ T+
Sbjct: 773 THQAESTEASGQTQT-SEPASSGSRTTSAGTATPSSSGASGTTPSGSEGISTSGETTRFS 831
Query: 489 SDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRG 548
S+ + D T L H A T PG F P L SE + G
Sbjct: 832 SN--PSRDSHTTQSTTELLSASASH--GAIPVSTGMASSIVPGTFHPTL----SEASTAG 883
Query: 549 SESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
+G + T S+S P + S Q T T +RG T S
Sbjct: 884 RPTGQSSPTSPSAS--------PQETAAISRMAQ-TQRTRTSRGSDTISLAS 926
Score = 38.1 bits (87), Expect = 0.025
Identities = 106/404 (26%), Positives = 144/404 (35%), Gaps = 80/404 (19%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGP--------GSTGNRNP-----GSSGTGGTAT 320
++S TG T P SS+ S SG + P STG+ P SS + G AT
Sbjct: 2358 ASSVSTGDTTPLPVTSSSSAS--SGHTTPLPVTDASSASTGDTTPLPVTDTSSASTGHAT 2415
Query: 321 WKP----GSSGPGSTGSWNSGSSGTGSTGNQNP---GSPRPGSTGTWNP---GSSERGSA 370
P S+ G T + + STG+ P S STG P + S
Sbjct: 2416 HLPVTGLSSASTGDTTRLPVTNVSSASTGHATPLPVTSTSSASTGDTTPLPGTDTSSVST 2475
Query: 371 GHWT-----SESSVS-GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGT 424
GH T SSVS G T + S P S +G+ P P T +G+ +P
Sbjct: 2476 GHTTPLLVTDASSVSTGDTTRLPVTS----PSSASTGHTTPL-PVTDTPSASTGDTTPLP 2530
Query: 425 RREYHTEKLVTSKGDKELRTGKE-KVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVV 483
VT+ R VTS S+ +T + S VT T GH T V
Sbjct: 2531 ---------VTNASSLSTRHATSLHVTSPSSASTGHATSLPVTDTSAASTGH--ATPLPV 2579
Query: 484 TSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSE 543
TS + + L G P +ASTG T P L +
Sbjct: 2580 TSTSSASTGDTTPLPVTDTYSASTG--QATPLPVTDTSSASTGDTTP------LPVTDTS 2631
Query: 544 TESRGSESGI-FTNTKESSSHHPGIAEFPSRGKSS---SYSKQFTSSTSYNRGDSTFESK 599
+ S G + + TNT S+ H S +S + T ++S + G +T
Sbjct: 2632 SASTGHATPLPVTNTSSVSTGHATPLHVTSPSSASTGHTTPLPVTDASSVSTGHAT---- 2687
Query: 600 SYKMADEAGSEADHEGTHSTKRGHAKSRPV------RGIHTSPL 637
S + D + S GHA S PV HT+PL
Sbjct: 2688 SLPVTDAS----------SVFTGHATSLPVTIPSSASSGHTTPL 2721
Score = 31.2 bits (69), Expect = 3.1
Identities = 65/255 (25%), Positives = 90/255 (35%), Gaps = 32/255 (12%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGS 333
++S TG T P +S+ S + P ++ P S+ TG S+ STG
Sbjct: 3862 TSSVSTGHATPLPVTSTSSVSTGHATPLPVTS----PSSASTGHATPVPVTSTSSASTGD 3917
Query: 334 W------NSGSSGTGSTGN---QNPGSPRPGSTGTWNPGSSERGSAGH-----WTSESSV 379
N+ S TG +P S G T T + S GH TS SSV
Sbjct: 3918 TTPLPVTNASSLSTGHATPLHVTSPSSASRGDTSTLPVTDASSASTGHATPLPLTSLSSV 3977
Query: 380 S-GSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP------GTRREYHTEK 432
S G T S S +G A P P +G+ +P + HT
Sbjct: 3978 STGDTTPLPVTDTS----SASTGQATPL-PVTSLSSVSTGDTTPLPVTIPSSASSGHTTS 4032
Query: 433 L-VTSKGDKELRTGKE-KVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSD 490
L VT G VTS S+ +T + VT T GH TS +
Sbjct: 4033 LPVTDASSVSTGHGTPLPVTSTSSASTGDTTPLPVTDTSSASTGHATPLPVTDTSSASTG 4092
Query: 491 CPEAMDLGTLSGIGT 505
+ + +LS + T
Sbjct: 4093 HATPLPVTSLSSVST 4107
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 58.5 bits (140), Expect = 2e-08
Identities = 99/383 (25%), Positives = 154/383 (40%), Gaps = 74/383 (19%)
Query: 271 RGGSTSYGTGSETESPRNPSSAGSWNSGSSGPG------STGNRNPGSSGTGGTATWKP- 323
RG S S + SE S + + + S + G +GP ST R+ G SG G+ ++
Sbjct: 3657 RGSSGSQASDSEGHSEDSDTQSVSAH-GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVS 3715
Query: 324 ---------GSSGPGSTG------------SWNSGSSGTGSTGNQNPGSPRPGSTGTWNP 362
G +GP + G S +S S T +PGS R G G+++
Sbjct: 3716 THEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHE 3775
Query: 363 GSSER-GSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVS 421
S +R G +G S ++ G + H +SGS S + N EE SG+ S
Sbjct: 3776 QSVDRSGHSGSHHSHTTSQGRSDASHGQSGS------RSASRETRN------EEQSGDGS 3823
Query: 422 PGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKE 481
+ +H E + + ++G+ + ++GS + R+ S + D E E
Sbjct: 3824 RHSGSRHH-EASTQADSSRHSQSGQGE-SAGSRRSRRQGSS-------VSQDSDSEAYPE 3874
Query: 482 VVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFV 541
SE S+ G+ S + DG RH ++ DTAS ++ P V
Sbjct: 3875 --DSERRSESASRNHHGS-SREQSRDGSRH---PGSSHRDTASHVQSSP----------V 3918
Query: 542 SETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDS--TFESK 599
S E G F++ + S++H GI S SSSY Q + T +G S +
Sbjct: 3919 QSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQ-SEGTERQKGQSGLVWRHG 3977
Query: 600 SYKMAD----EAGSEADHEGTHS 618
SY AD E+G G+ S
Sbjct: 3978 SYGSADYDYGESGFRHSQHGSVS 4000
Score = 47.0 bits (110), Expect = 5e-05
Identities = 86/381 (22%), Positives = 137/381 (35%), Gaps = 61/381 (16%)
Query: 275 TSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSW 334
+S+ T PS+ G S +R+ S T PGSS G GS+
Sbjct: 1446 SSHEQSESTHGQTAPSTGGRQGSRHE-QARNSSRHSASQDGQDTIRGHPGSSRGGRQGSY 1504
Query: 335 N------SGSSG---------TGSTGNQNPGSPRPGSTGTWN-----PGSSERGSAGHWT 374
+ SG SG S + PR S T N GS GS H
Sbjct: 1505 HEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEP 1564
Query: 375 SE---SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
S SS GQ S +GS GS ++ + + G E+ +R Y +
Sbjct: 1565 STRAGSSRHSQVGQGES-AGSKTSRRQGSSVSQDRDSE-GHSEDSERRSESASRNHYGSA 1622
Query: 432 KLVTSKGDKELRTGKE-KVTSGSTTTTRRSCSKTVTKTVIGPD--GHKEVTKEVVTSEDG 488
+ + G + R+ +E + + G + + R +T G +E + G
Sbjct: 1623 REQSRHGSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHG 1682
Query: 489 SDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRG 548
S ++ D T SG G R D + D+ + G + G S++E
Sbjct: 1683 SRHQQSADSSTDSGTG-------RRQDSSVVGDSGNRGSS---------GSQASDSEGHS 1726
Query: 549 SESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS--YKMADE 606
ES +T+ S+H G++ + + ST G+ + S S Y+++
Sbjct: 1727 EES----DTQSVSAH----------GQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTH 1772
Query: 607 AGSEADHEGTHSTKRGHAKSR 627
SE+ H T + G +SR
Sbjct: 1773 EQSESAHGRTGPSTGGRQRSR 1793
Score = 46.6 bits (109), Expect = 7e-05
Identities = 90/390 (23%), Positives = 143/390 (36%), Gaps = 34/390 (8%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW 321
E+ G+ +R +S S++E + S S ++ + GS+ ++ S G
Sbjct: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQE 1314
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGN-----------QNPGSPRPGSTGTWNPGSSERGSA 370
S G + S SG+ T S+ + +PG R GS + SS
Sbjct: 1315 DRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGE-RHGSRHQQSADSSRHSGI 1373
Query: 371 GHWTSESSV-----SGSTGQWHSESGSFRPDS-----PGSGNARPNNPDWGTFEEVSGNV 420
GH + S+V GS+G + S DS G A P+
Sbjct: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGE 1433
Query: 421 SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK 480
S G R + + V+S E G+ ++G +R ++ ++ DG +
Sbjct: 1434 SSGRSRSFLYQ--VSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRG 1491
Query: 481 EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPML-GE 539
+S G SG G+ H H D AS G++ P S E
Sbjct: 1492 HPGSSRGGRQGSYHEQSVDRSG---HSGYHHSHTTPQGRSD-ASHGQSGPRSASRQTRNE 1547
Query: 540 FVSETESRGSESGIF-TNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFES 598
S SR S S +T+ SS H + + S G S S++ SS S +R DS S
Sbjct: 1548 EQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAG--SKTSRRQGSSVSQDR-DSEGHS 1604
Query: 599 KSYKMADEAGSEADHEGTHSTKRGHAKSRP 628
+ + E+ S +H G+ + H P
Sbjct: 1605 EDSERRSESASR-NHYGSAREQSRHGSRNP 1633
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/383 (22%), Positives = 141/383 (36%), Gaps = 39/383 (10%)
Query: 266 GNEITRG--GSTSYGT-GSETESPRNPSS-AGSWNSGSSGPG-STGNRNPGSSGTGGTAT 320
G + RG GS+ G GS E + S +GS +S ++ G S +R S + T
Sbjct: 3430 GQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQT 3489
Query: 321 WKPGSSGPGSTGSWN----SGSSGTGSTGNQNPGSPRPGSTGTWNPGSS---ERGSAGHW 373
SG GS SW+ + + S +Q+ G + N GSS + S GH
Sbjct: 3490 RNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHS 3549
Query: 374 TSESSVSGSTGQWH-------SESGSFRP-----DSPGSGNARPNNPDWGTFEEVSGNVS 421
SGS + H S GS P D G G++ ++ GT + N S
Sbjct: 3550 EDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHH--AENSS 3607
Query: 422 PGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKE 481
G H E+ +S G+ R G S + ++ + + GH+ +
Sbjct: 3608 GGQAASSH-EQARSSAGE---RHGSHHQQS-ADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662
Query: 482 VVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFV 541
+ +G E D ++S G + H + +G++ + E
Sbjct: 3663 QASDSEGHS--EDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE-- 3718
Query: 542 SETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSY 601
++ES +G T ++ S H A SR +S + +R S
Sbjct: 3719 -QSESAHGRAGPSTGGRQGSRHEQ--ARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHE 3775
Query: 602 KMADEAGSEADHEGTHSTKRGHA 624
+ D +G H +H+T +G +
Sbjct: 3776 QSVDRSGHSGSHH-SHTTSQGRS 3797
Score = 44.7 bits (104), Expect = 3e-04
Identities = 87/378 (23%), Positives = 137/378 (36%), Gaps = 63/378 (16%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT-WKPGSSGPGST 331
G T TG S + S +S S T + +PGSS G + ++ G +
Sbjct: 2429 GRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHS 2488
Query: 332 GSWNSGSSGTG-STGNQNPGSPRPGSTGTWN-----PGSSERGSAGHWTS---ESSVSGS 382
GS +S ++ G S + R S T N GS GS H S +SS
Sbjct: 2489 GSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQ 2548
Query: 383 TGQWHSE--------SGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLV 434
GQ SE SF DS G++ + E SG+ S R + + +
Sbjct: 2549 VGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDS-------ERWSGSAS---RNHHGSAQEQ 2598
Query: 435 TSKGDKELRTGKE-KVTSGSTTTTRRSCSKTVTKTVIGPD--GHKEVTKEVVTSEDGSDC 491
G + R+ +E + G + + R T+T G E + GS
Sbjct: 2599 LRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHH 2658
Query: 492 PEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSES 551
++ D SGIG +A D+ G + G S+ E +S
Sbjct: 2659 QQSADSSRHSGIG-------HGQASSAVRDSGHRGYS---------GSQASDNEGHSEDS 2702
Query: 552 GIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS--YKMADEAGS 609
+T+ S+H G++ S+ + S G+++ S S Y+++ S
Sbjct: 2703 ----DTQSVSAH----------GQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQS 2748
Query: 610 EADHEGTHSTKRGHAKSR 627
E+ H T + RG SR
Sbjct: 2749 ESSHGWTGPSTRGRQGSR 2766
Score = 43.9 bits (102), Expect = 5e-04
Identities = 85/357 (23%), Positives = 130/357 (36%), Gaps = 29/357 (8%)
Query: 280 GSETESPRNPSSAGSWNSGSSGPGST-GNRNPGSSGTGGTATWKPGSSG--PGSTGSWNS 336
G +S R+ SA + GS+ S G+R+P S + S G+ + S
Sbjct: 305 GHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETS 364
Query: 337 GSSGTGSTGNQNPGSP--RPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFR 394
T S+ Q SP R GS + SS + G + S+VS + SGS
Sbjct: 365 SRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRGQASSAVSDRGHR--GSSGSQA 422
Query: 395 PDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGST 454
DS G N D + VSG+ G R++ H E G++ R+G +
Sbjct: 423 SDSEGHSE----NSDT---QSVSGHGKAGLRQQSHQESTRGRSGERSGRSGSSLYQVSTH 475
Query: 455 TTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHP 514
+ +T T T H E ++ + + + S G G H
Sbjct: 476 EQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQS 535
Query: 515 -DEAAFFDTASTGKTFPGFFSPMLGEFVSETESR--GSESGIFTNTKESSSHHPGIAEFP 571
+ + + + T G G+ S + SR +E T+ S S H E
Sbjct: 536 VNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRH---HEAS 592
Query: 572 SRGKSSSYSK--QFTSS---TSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGH 623
S+ SS +S+ Q SS TS N+G S + + SE + S R H
Sbjct: 593 SQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSD----SQGHSEDSERWSGSASRNH 645
Score = 43.9 bits (102), Expect = 5e-04
Identities = 83/393 (21%), Positives = 132/393 (33%), Gaps = 54/393 (13%)
Query: 279 TGSETESPRNPS---SAGSWNSGSSGPG-------STGNRNPGSSGTGGTATWKPGSSG- 327
+G + P S SA W+ G SG ST ++ + G T+T + S
Sbjct: 1087 SGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHH 1146
Query: 328 -PGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGS----------------A 370
S +S S T +PGS R G G+ + S +R A
Sbjct: 1147 EQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDA 1206
Query: 371 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
H S S + + +SG S + + D +V S G+R H
Sbjct: 1207 SHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQ 1266
Query: 431 EKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKT-VIGPDGHKEVTKEVVTSED-- 487
V+ D E + + SGS + S+ ++ P H+E S D
Sbjct: 1267 GSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSS 1326
Query: 488 ---GSDCPEAMDLG--------TLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPM 536
G+ E+ G S G G RH+ ++ G
Sbjct: 1327 RQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQ---------SADSSRHSGIGHRQ 1377
Query: 537 LGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTF 596
V ++ RGS TN+ E S + G++ + + S G+S+
Sbjct: 1378 ASSAVRDSGHRGSSGSQVTNS-EGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSG 1436
Query: 597 ESKS--YKMADEAGSEADHEGTHSTKRGHAKSR 627
S+S Y+++ SE+ H T + G SR
Sbjct: 1437 RSRSFLYQVSSHEQSESTHGQTAPSTGGRQGSR 1469
Score = 43.9 bits (102), Expect = 5e-04
Identities = 86/373 (23%), Positives = 132/373 (35%), Gaps = 27/373 (7%)
Query: 281 SETESPRNPSSAGSWNSGSS-GPGSTGNRNPGSSG-TGGTATWKPGSSGPGSTGSWNSGS 338
S ES R S S +SGS ST ++ S G TG + + GS + S +
Sbjct: 2719 SHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA 2778
Query: 339 SGTGS-TGNQNPGSPRPGSTGTWNPGSSER-GSAG----HWTSESSVSGSTGQWHSESGS 392
S G T +PGS R G G + S + G +G H TS+ S GQ S S S
Sbjct: 2779 SQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 2838
Query: 393 F-----RPDSPGSGNARPNNPDWGTFEEVSGNV------SPGTRREYHTEKLVTSKGDKE 441
GS ++ + + T ++S + S G+RR V+ D E
Sbjct: 2839 RTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE 2898
Query: 442 LRTGKEKVTSGSTTTTRR-SCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL 500
+ + SGS + S + + P H+E S D S T
Sbjct: 2899 GHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS 2958
Query: 501 SGIGTLDGFRHRHPD----EAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTN 556
SG + ++ G V ++ RG SG +
Sbjct: 2959 SGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG-YSGSQAS 3017
Query: 557 TKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS--YKMADEAGSEADHE 614
E S + G++ S+ + S G+++ S S Y+++ SE+ H
Sbjct: 3018 DNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHG 3077
Query: 615 GTHSTKRGHAKSR 627
T + RG SR
Sbjct: 3078 WTGPSTRGRQGSR 3090
Score = 41.2 bits (95), Expect = 0.003
Identities = 80/375 (21%), Positives = 133/375 (35%), Gaps = 34/375 (9%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGST 331
G S S T +N SS + +S S G R+ + + +G G
Sbjct: 671 GHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQA 730
Query: 332 GSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGH--WTSESSVSGSTGQWHSE 389
S S GS+G+Q S S + S G AGH + + S +G+
Sbjct: 731 SSAVRDSGHRGSSGSQATDS-EGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRR 789
Query: 390 SGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKV 449
SGSF + ++ G S G R+ H E+ + + G++ +
Sbjct: 790 SGSFLYQVSTHKQSESSHGWTGP--------STGVRQGSHHEQARDNSRHSASQDGQDTI 841
Query: 450 TSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTL--- 506
G ++RR + + + GH TS+ SD G+ S T
Sbjct: 842 -RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQS-GSRSASRTTRNE 899
Query: 507 ----DGFRH---RHPDEAAFFD-----TASTGKTFPGFFSPMLGEFVS-ETESRGSESGI 553
DG RH RH + ++ D A G++ S G VS +++S G
Sbjct: 900 EQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDS 959
Query: 554 FTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADH 613
+ +S +H G A+ SR + + S +R + S + + +E
Sbjct: 960 ERWSGSASRNHRGSAQEQSR-----HGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSS 1014
Query: 614 EGTHSTKRGHAKSRP 628
G ++ A+S P
Sbjct: 1015 GGQAASSHEQARSSP 1029
Score = 37.7 bits (86), Expect = 0.033
Identities = 94/415 (22%), Positives = 137/415 (33%), Gaps = 64/415 (15%)
Query: 262 ERPGG-NEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGN------RNPGSSG 314
ER G ++ + ST GTG +S S +SGS S G+ ++ + G
Sbjct: 1679 ERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVSAHG 1738
Query: 315 TGGTATWKPGSSGPGSTG--SWNSGS------------SGTGSTGNQNPGSPRP------ 354
G S G +G S SGS S G TG G R
Sbjct: 1739 QAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQAR 1798
Query: 355 -----------GSTGTWNPGSSERGSAG-HWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
T +PGSS G G H+ SG +G HS + S G
Sbjct: 1799 DSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQ 1858
Query: 403 ARPNNPDWGT-FEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSC 461
+ + T E+ SG+ S + +H +S+ D + + S T+R
Sbjct: 1859 SGSRSVSRQTRNEKQSGDGSRHSGSRHHE---ASSRADSSRHSQVGQGQSSGPRTSRNQG 1915
Query: 462 SKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRH---RHPDEAA 518
S + GH E SE S LG+ + + DG RH H D A
Sbjct: 1916 SSVSQDS--DSQGHSE------DSERWSGSASRNHLGS-AWEQSRDGSRHPGSHHEDRAG 1966
Query: 519 FFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSS 578
+A + S G +E+ SRG + + S+ G SS
Sbjct: 1967 HGHSADS--------SRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSR 2018
Query: 579 YSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIH 633
+S S DS S A ++ ++ T S K+ P + H
Sbjct: 2019 HSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS-AQGKAGPHQQSH 2072
Score = 37.4 bits (85), Expect = 0.043
Identities = 80/372 (21%), Positives = 124/372 (33%), Gaps = 32/372 (8%)
Query: 271 RGGSTSYGTGSETESPRNPSSAGSWNSGSSGP----GSTGNRNPGS-----SGTGGTATW 321
+G S S + SE S + +GS + G G+R+P S +G G +A
Sbjct: 3211 QGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADR 3270
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
S + S ++ + +PG R GS + SS + S+V
Sbjct: 3271 SRQSGTRHAETSSGGQAASSHEQARSSPGE-RHGSRHQQSADSSRHSGIPRGQASSAVRD 3329
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
S W S SGS DS G + VSG+ G ++ H E G +
Sbjct: 3330 SR-HWGS-SGSQASDSEGHSEESDT-------QSVSGHGQAGPHQQSHQESARDRSGGRS 3380
Query: 442 LRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEV---VTSEDGSDCPEAMDLG 498
R+G + + + +T T T H E ++ S++G D
Sbjct: 3381 GRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHP-- 3438
Query: 499 TLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESR----GSESGIF 554
S G + D + + + T G G+ S + SR +SG
Sbjct: 3439 GSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDG 3498
Query: 555 TNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHE 614
+ S H SR S + TS N+G S + + SE
Sbjct: 3499 SRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDSD----SQGHSEDSER 3554
Query: 615 GTHSTKRGHAKS 626
+ S R H S
Sbjct: 3555 WSGSASRNHRGS 3566
Score = 35.8 bits (81), Expect = 0.13
Identities = 83/386 (21%), Positives = 138/386 (35%), Gaps = 35/386 (9%)
Query: 270 TRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG--GTATW--KPGS 325
+R + G + + RN S+ S +S S G R GS+ G+A + GS
Sbjct: 3516 SRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGS 3575
Query: 326 SGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSE--RGSAG-----HWTSESS 378
P S +G + + Q+ S+G S E R SAG H +
Sbjct: 3576 RHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSAD 3635
Query: 379 VSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEE------VSGNVSPGTRREYHTEK 432
S +G H ++ S DS G++ D E VS + G ++ H E
Sbjct: 3636 SSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQE- 3694
Query: 433 LVTSKGDKELRTGKEK--VTSGSTTTTRRSCSKTVTKTVIGPDG--HKEV--TKEVVTSE 486
+++G R+G+ + ST S + G G H++ + S+
Sbjct: 3695 --STRGRSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQ 3752
Query: 487 DGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSET-- 544
+G D G+ G G + + D + + + T G G+ S +
Sbjct: 3753 EGQDTIRGHP-GSRRG-GRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 3810
Query: 545 -ESRGSESGIFTNTKESSSHHPGIAEF-PSRGKSSSYSKQFTSSTSYNRGDST---FESK 599
E+R E + S HH + SR S + S S +G S +S+
Sbjct: 3811 RETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSE 3870
Query: 600 SYKMADEAGSEADHEGTHSTKRGHAK 625
+Y E SE+ H + R ++
Sbjct: 3871 AYPEDSERRSESASRNHHGSSREQSR 3896
Score = 34.3 bits (77), Expect = 0.37
Identities = 90/436 (20%), Positives = 143/436 (32%), Gaps = 96/436 (22%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGS-SGPGST 331
G T TG S + S +S S T +PGSS G + S + G +
Sbjct: 483 GRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHS 542
Query: 332 GSWNS------------GSSGTGSTGNQNPGSPRPG------------------------ 355
GS +S G SG+ S Q + G
Sbjct: 543 GSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQ 602
Query: 356 -----STG---TWNPGSS---ERGSAGHWTSESSVSGSTGQWH-------SESGSFRP-- 395
S+G + N GSS + S GH SGS + H S GS P
Sbjct: 603 VGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRS 662
Query: 396 ---DSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSG 452
D G G++ ++ GT + N S G H E+ +S G+ R G
Sbjct: 663 HHEDRAGHGHSADSSRKSGT--RHTQNSSSGQAASSH-EQARSSAGE---RHGSRHQLQS 716
Query: 453 STTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHR 512
+ ++ + + GH+ + T +G E D ++SG G +
Sbjct: 717 ADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHS--EDSDTQSVSGHGQAGHHQQS 774
Query: 513 HPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSH--------- 563
H + A D + G F + ++ES +G T ++ S H
Sbjct: 775 HQESAR--DRSGERSRRSGSFLYQVSTH-KQSESSHGWTGPSTGVRQGSHHEQARDNSRH 831
Query: 564 ------------HPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEA 611
HPG + RG+ S+ +Q + ++ G + S +D + ++
Sbjct: 832 SASQDGQDTIRGHPGSSR---RGRQGSHHEQSVDRSGHS-GSHHSHTTSQGRSDASRGQS 887
Query: 612 DHEGTHSTKRGHAKSR 627
T R +SR
Sbjct: 888 GSRSASRTTRNEEQSR 903
Score = 33.9 bits (76), Expect = 0.48
Identities = 79/352 (22%), Positives = 124/352 (35%), Gaps = 58/352 (16%)
Query: 271 RGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGST----GNRNPGS-----SGTGGTATW 321
+G S S + SE S + +GS + G G+R+P S +G G +A
Sbjct: 2887 QGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRHPRSHQEDRAGHGHSAD- 2945
Query: 322 KPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
SG T + + G + + ++ R GS + SS GH + S+V
Sbjct: 2946 SSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRD 3005
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
S + +S GS D+ G ++ D T + VS + G+ ++ H E G+
Sbjct: 3006 SGHRGYS--GSQASDNEG------HSEDSDT-QSVSAHGQAGSHQQSHQESARGRSGETS 3056
Query: 442 LRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL- 500
+G + ST S + G G + + + S + G
Sbjct: 3057 GHSGSF-LYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPG 3115
Query: 501 SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKES 560
S G G+ H H + S+G + G S T S+G
Sbjct: 3116 SSRGGRQGYHHEHSVD-------SSGHS---------GSHHSHTTSQGRSDA-------- 3151
Query: 561 SSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEAD 612
SRG+S S S T+ GDS+ S S EA + AD
Sbjct: 3152 -----------SRGQSGSRSASRTTRNEEQSGDSSRHSVS--RHHEASTHAD 3190
Score = 33.9 bits (76), Expect = 0.48
Identities = 53/198 (26%), Positives = 76/198 (38%), Gaps = 19/198 (9%)
Query: 281 SETESPRNPSSAGSWNSGSS-GPGSTGNRNPGSSG-TGGTATWKPGSSGPGSTGSWNSGS 338
S ES R S S +SGS ST ++ S G TG + + GS + S +
Sbjct: 3043 SHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHSA 3102
Query: 339 SGTGS-TGNQNPGSPRPGSTGTWNPGSSER-GSAG----HWTSESSVSGSTGQWHSESGS 392
S G T +PGS R G G + S + G +G H TS+ S GQ S S S
Sbjct: 3103 SQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 3162
Query: 393 --FRPDSPGSGNARPN---------NPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
R + ++R + + D + S G+RR V+ D E
Sbjct: 3163 RTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSE 3222
Query: 442 LRTGKEKVTSGSTTTTRR 459
+ + SGS + R
Sbjct: 3223 GHSEDSERWSGSASRNHR 3240
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 58.2 bits (139), Expect = 2e-08
Identities = 87/357 (24%), Positives = 140/357 (39%), Gaps = 37/357 (10%)
Query: 80 DFTNRINKLKNSLFEYQKNNKDSHS-LTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRI 138
D + L+ L +KN+K+ S LT + + + A +D T + D+R
Sbjct: 273 DLEMQYETLQEELMALKKNHKEEMSQLTGQNSGDVNVEINVAPGKDLT--KTLNDMRQEY 330
Query: 139 EVL---KRKVIEKVQHIQLLQ---------KNVRAQLVDMKRLEVDIDIKIRSCRGSCSR 186
E L RK IE Q+ Q + V++ ++ +L + + S+
Sbjct: 331 EQLIAKNRKDIENQYETQITQIEHEVSSSGQEVQSSAKEVTQLRHGVQELEIELQSQLSK 390
Query: 187 ALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPP 246
A E L+D +++ Q+I ++ + + + Q + D+ + +++
Sbjct: 391 KAALEKSLEDTKNRYCGQLQMI-QEQISNLEAQ---------ITDV-----RQEIECQNQ 435
Query: 247 EWKALTDMPQMRMELERPGGNEITRGGSTSY---GTGSETESPRNPSSAGSWNSGSSGPG 303
E+ L + +MR+E E + + GG + G G R S GS+ GS G G
Sbjct: 436 EYSLLLSI-KMRLEKEIETYHNLLEGGQEDFESSGAGKIGLGGRG-GSGGSYGRGSRG-G 492
Query: 304 STGNRNPGSSGTG-GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNP 362
S G+ G SG G G + G SG G SG G G + G GS G +
Sbjct: 493 SGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSG 552
Query: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGN 419
GS G + S G G S GS GSG + +G EE SG+
Sbjct: 553 GSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Score = 53.9 bits (128), Expect = 4e-07
Identities = 42/119 (35%), Positives = 53/119 (44%), Gaps = 8/119 (6%)
Query: 265 GGNEITRGGST-SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
GG +RGGS SYG GS + S G + GS G S G+ S G+GG
Sbjct: 507 GGGSGSRGGSGGSYGGGSGS----GGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS 562
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPG--STGTWNPGSSERGSAGHWTSESSVS 380
GS G GS G + GS G +G + G G S G++ G GS G + S S
Sbjct: 563 GSGG-GSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGGYGGGSGKS 620
Score = 45.1 bits (105), Expect = 2e-04
Identities = 46/144 (31%), Positives = 54/144 (37%), Gaps = 15/144 (10%)
Query: 261 LERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
L R GG GG G+G S + S SSG G G R SSG GG ++
Sbjct: 11 LSRSGG-----GGGGGLGSGGSIRSSYSRFS-------SSGGGGGGGRFSSSSGYGGGSS 58
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGST---GTWNPGSSERGSAGHWTSES 377
G G GS G G SG G + + G GS G G S G G
Sbjct: 59 RVCGRGGGGSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGG 118
Query: 378 SVSGSTGQWHSESGSFRPDSPGSG 401
S G G + S G F G+G
Sbjct: 119 SGGGFGGGYGSGFGGFGGFGGGAG 142
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/107 (26%), Positives = 37/107 (34%), Gaps = 1/107 (0%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPG 324
GG S+ YG GS R + ++ G G + G G GG + G
Sbjct: 41 GGGGGRFSSSSGYGGGSSRVCGRGGGGSFGYSYGGGSGGGFSASSLGG-GFGGGSRGFGG 99
Query: 325 SSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAG 371
+SG G + S G G +G G G G G G G
Sbjct: 100 ASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGFGGFGGFGGGAGGGDG 146
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 58.2 bits (139), Expect = 2e-08
Identities = 71/362 (19%), Positives = 134/362 (37%), Gaps = 11/362 (3%)
Query: 267 NEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSS 326
N + G SY + ++ S G+ + S T N + +G G S
Sbjct: 483 NNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDS 542
Query: 327 GPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQW 386
G G + S +S SS + ++ + + S S SS+ S+ +S+SS S S+
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSN---SSSDSDSSDSDSSDSSDSDSSDSS 599
Query: 387 HSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGK 446
+S S DS S ++ ++ + + S + ++ + D
Sbjct: 600 NSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSD----NSD 655
Query: 447 EKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTL 506
+S S+ ++ S S + + D + + S D S+ E+ D S +
Sbjct: 656 SSDSSNSSNSSDSSDSSDSSDSSSSSDSSN--SSDSSDSSDSSNSSESSDSSDSSDSDSS 713
Query: 507 DGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKES--SSHH 564
D + + + + S+ + S S S S+S +N+ +S SS
Sbjct: 714 DSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDS 773
Query: 565 PGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHA 624
++ + S+ S SS S N DS+ S S +D + S++ + S +
Sbjct: 774 SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSS 833
Query: 625 KS 626
S
Sbjct: 834 DS 835
Score = 54.7 bits (130), Expect = 3e-07
Identities = 71/369 (19%), Positives = 133/369 (36%), Gaps = 32/369 (8%)
Query: 253 DMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAG--SWNSGSSGPGSTGNRNP 310
D M+ + P ++ + G + +ES N SS G S+NS S G+ +
Sbjct: 454 DFDDKSMQGDDPNSSDESNGNDDA-----NSESDNNSSSRGDASYNSDESKDNGNGSDSK 508
Query: 311 GSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSA 370
G+ +T + + NS S+G G+ GN + G + + S S+
Sbjct: 509 GAEDDDSDST----------SDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSS 558
Query: 371 GHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
S S + +S S S DS S ++ ++ D + S + +
Sbjct: 559 NSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSD--- 615
Query: 431 EKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSD 490
S + ++ K S S+ + +S S + + + S D SD
Sbjct: 616 -----SSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSD 670
Query: 491 CPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSE 550
++ D + S D + D++++ ++ S S S +
Sbjct: 671 SSDSSDSSSSSD-------SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNS 723
Query: 551 SGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSE 610
S ++ SS ++ SS+ S SS S N DS+ S S +D + S
Sbjct: 724 SDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSS 783
Query: 611 ADHEGTHST 619
++ ++S+
Sbjct: 784 DSNDSSNSS 792
Score = 52.8 bits (125), Expect = 1e-06
Identities = 66/351 (18%), Positives = 139/351 (39%), Gaps = 19/351 (5%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGS 333
S+ S+++S + SS+ S +S S S+ + + SS + ++ S S+ S
Sbjct: 560 SSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDS 619
Query: 334 WNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSF 393
+S S + S + + + S+ + + SS+ + ++ S+ S S+ S S
Sbjct: 620 SDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSS 679
Query: 394 RPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGS 453
DS S ++ ++ + E + S + ++ ++ D + + +S S
Sbjct: 680 SSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSD--SSDS 737
Query: 454 TTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRH 513
+ ++ S S + + D + + S D SD ++ D S +
Sbjct: 738 SNSSDSSDSSDSSNSSDSSD-----SSDSSNSSDSSDSSDSSDSSDSSNSSDSN------ 786
Query: 514 PDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSR 573
D + D++ + + S + ++S S S +N+ +SS + S
Sbjct: 787 -DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD-----SSNSSD 840
Query: 574 GKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHA 624
SS S + S S NR DS+ S S +D + S + + S + ++
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNS 891
Score = 48.9 bits (115), Expect = 1e-05
Identities = 66/350 (18%), Positives = 119/350 (34%), Gaps = 3/350 (0%)
Query: 267 NEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSS 326
+E + S + S S + SS S NS S S + + SS + + + +S
Sbjct: 924 SESSNSSDNSNSSDSSNSSDSSDSSDSS-NSSDSSNSSDSSNSSDSSDSNSSDSSDSSNS 982
Query: 327 GPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQW 386
S S +S SS + + N + S S+ + N S S +S+SS S +
Sbjct: 983 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDS 1042
Query: 387 HSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGK 446
S S + + ++ D + S + E ++ D +
Sbjct: 1043 SDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDS 1102
Query: 447 EKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTL 506
+ S ++ S + + + + S D SD E+ D S
Sbjct: 1103 SDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDS 1162
Query: 507 DGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESS--SHH 564
+ + S+ + S S S S+S +++ +SS S
Sbjct: 1163 SDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDS 1222
Query: 565 PGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHE 614
++ +SS S SS S N DS+ S S ++ E+D +
Sbjct: 1223 SDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQ 1272
Score = 46.6 bits (109), Expect = 7e-05
Identities = 74/370 (20%), Positives = 138/370 (37%), Gaps = 11/370 (2%)
Query: 260 ELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTA 319
E N + S S + ++S + S+ S +S +S S N + S + +
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Query: 320 TWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
+ S S S +S SS + + + + S S+ + + +S S +S+SS
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 380 SG----STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEV----SGNVSPGTRREYHTE 431
S S+ +S S DS S ++ ++ + E S N S + ++
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD 1104
Query: 432 KLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEV-TKEVVTSEDGSD 490
+S + +S S+ ++ S S + + D + + + S D SD
Sbjct: 1105 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSD 1164
Query: 491 CPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSE 550
++ D S + + S+ + S S S S+
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Query: 551 SGIFTNTKESS-SHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADE-AG 608
S +++ ESS S + S SS S + STS + +S +SKS + +
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSD 1284
Query: 609 SEADHEGTHS 618
S++D EG+ S
Sbjct: 1285 SDSDSEGSDS 1294
Score = 45.4 bits (106), Expect = 2e-04
Identities = 73/382 (19%), Positives = 134/382 (35%), Gaps = 41/382 (10%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGS---------------SGPGSTGNRNP 310
GN T+G + + P N G N+GS S G N +
Sbjct: 412 GNVKTQGEVVNIEGPGQKSEPGN--KVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSD 469
Query: 311 GSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSP-----------RPGSTGT 359
S+G + +S S+NS S G+ + G+ S G
Sbjct: 470 ESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGN 529
Query: 360 WNPGS--SERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVS 417
N G+ +++ +G S+SS S S+ +S S DS S + ++ D S
Sbjct: 530 GNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSD-------S 582
Query: 418 GNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKE 477
+ + + S + + S ++ ++ SK+ + + D +
Sbjct: 583 SDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDS---SDSDSK 639
Query: 478 VTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPML 537
S D SD ++ D S + D ++ D++++ + S
Sbjct: 640 SDSSDSNSSDSSDNSDSSDSSNSSN-SSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNS 698
Query: 538 GEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFE 597
E ++S S+S +++ S+S + SS+ S SS S N DS+
Sbjct: 699 SESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDS 758
Query: 598 SKSYKMADEAGSEADHEGTHST 619
S S +D + S + + S+
Sbjct: 759 SDSSNSSDSSDSSDSSDSSDSS 780
Score = 35.8 bits (81), Expect = 0.13
Identities = 63/313 (20%), Positives = 118/313 (37%), Gaps = 33/313 (10%)
Query: 314 GTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
GTG A P G+ G+G ++ G+ + S + + G
Sbjct: 232 GTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDEEAGNGKDSSNNSKGQEGQDHGKEDDH 291
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV--SPGTRREYHTE 431
S + + +++ G P + G+ + EE S + G++R T+
Sbjct: 292 DSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKS------EENSAGIPEDNGSQRIEDTQ 345
Query: 432 KLVTSKGDKELRTGKEKVTSGSTT-TTRRSCSKTVTKTVIGP-DGHKEVTKEVVTSEDGS 489
KL +E + + ++T S T +S K + + GP G++ +TKEV +G
Sbjct: 346 KL----NHRESKRVENRITKESETHAVGKSQDKGI--EIKGPSSGNRNITKEVGKGNEGK 399
Query: 490 DCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGS 549
+ + G + G G + + + G+ S++ S G
Sbjct: 400 E--DKGQHGMILGKGNV-------KTQGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGY 450
Query: 550 ESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYK----MAD 605
+S F + K P ++ S G + S+ +S+S RGD+++ S K +D
Sbjct: 451 DSYDF-DDKSMQGDDPNSSD-ESNGNDDANSESDNNSSS--RGDASYNSDESKDNGNGSD 506
Query: 606 EAGSEADHEGTHS 618
G+E D + S
Sbjct: 507 SKGAEDDDSDSTS 519
>gi|239755776 PREDICTED: similar to Mucin-19 [Homo sapiens]
Length = 1950
Score = 57.4 bits (137), Expect = 4e-08
Identities = 89/340 (26%), Positives = 132/340 (38%), Gaps = 41/340 (12%)
Query: 265 GGNEITRGGSTSYGTGSETESPR----NPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
GG + G+ S T +PR P+ G G +GPG+T + + G S G+ T
Sbjct: 1593 GGVDAATTGAASENTSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVS--AGSIT 1650
Query: 321 WKPGSSGPGSTGSWNSGSSG------TGSTGNQNPGSPRPGSTG-TWNPGSSERGSAGHW 373
PG+S S S SG++G TG+T ++ S G +G T S GS
Sbjct: 1651 ASPGASATSSESS-KSGTTGPSVGGKTGATSSEATSS--EGMSGVTGQSLGSTAGSDSEI 1707
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGS-GNARPNNPDWGTFEEVSGNVSPGTRREYHTEK 432
T+++S +GS S G SPGS G+ +WG + G E +
Sbjct: 1708 TAKTSFTGS-----SPPGKLTRPSPGSPGHFSGGTTEWGNV------ATTGAAGENTSGA 1756
Query: 433 LVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCP 492
L +++G E T SG+T T + T + G V+ GS P
Sbjct: 1757 LGSTEGSVEATT---SAGSGNTAGTSGTGDTGPGNTAV--SGTPVVSPGATPGAPGSSTP 1811
Query: 493 EAMDLGTLS-GIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSES 551
D+G S G G AF T SP+ T++ + +
Sbjct: 1812 GEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPV----SKHTDAASATA 1867
Query: 552 GIFTNTKESSSHHPGIAEFPSRGK-SSSYSKQFTSSTSYN 590
+ +K + PG A S GK +S +S TS+ S N
Sbjct: 1868 VTISGSKPGTPGTPGGA--TSGGKITSGWSSSGTSTGSSN 1905
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSG 314
P ++ PG GG+T +G + T + +S ++ S +T + ++G
Sbjct: 1718 PPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAG 1777
Query: 315 TGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGH 372
T GT +GPG+T + G+T PGS PG N + G +GH
Sbjct: 1778 TSGTG-----DTGPGNTAVSGTPVVSPGATPGA-PGSSTPGEADIGNTSFGKSGKSGH 1829
Score = 41.6 bits (96), Expect = 0.002
Identities = 56/212 (26%), Positives = 79/212 (37%), Gaps = 26/212 (12%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313
P +E PG E G+ ++P AG + + SS G + P S
Sbjct: 35 PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 89
Query: 314 --GTGGTATWKPGSSGPGST--------GSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362
G G A K G S + G + GSS +G + + P S G+TG
Sbjct: 90 GLGAPGKAEDKSGDSQDAGSSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 149
Query: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422
S ER AG+ SE S + ST + S SG + WG +E VS
Sbjct: 150 KSRERWDAGNSRSEDSPADSTNTRYGAGFS------SSGASLDVGFGWGISDEKGLEVSK 203
Query: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGST 454
RE S G + + G + V +GS+
Sbjct: 204 ADGRETRGS---GSAGGETIVFGPDAVGTGSS 232
Score = 37.7 bits (86), Expect = 0.033
Identities = 52/223 (23%), Positives = 78/223 (34%), Gaps = 34/223 (15%)
Query: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346
+SGS+ G GN + G G G ++ + G SSG GSS TG
Sbjct: 453 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 512
Query: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPN 406
S P G +PGS S G+ S S SG G+ E G G+
Sbjct: 513 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG------VGASGLNEF 566
Query: 407 NPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRT---GKEKVTSGSTTTTRRSCSK 463
+ E ++ T + T ++ E+ T G K +G SC
Sbjct: 567 GETGLSGSEKGSHIPEATPKYSETNAII-----GEISTWSKGAYKSFNGRIFFFESSCPY 621
Query: 464 TVTKTVIGPDG-----------HKEVTKEVVTSEDGSDCPEAM 495
T + I G +++ + + S+ DCP A+
Sbjct: 622 TFCRHCIESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAV 664
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338
TG + +P AG+ + GS S GN SG+GG G G SG
Sbjct: 510 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 563
Query: 339 SGTGSTG--NQNPGSPRPGSTGTWNPGSSERGSAGHWT 374
+ G TG GS P +T ++ ++ G W+
Sbjct: 564 NEFGETGLSGSEKGSHIPEATPKYSETNAIIGEISTWS 601
Score = 29.6 bits (65), Expect = 9.0
Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSG---PGSTGNRNPGSSGTGG-TATWKPGSSGPG 329
+T YG G + G S G + G GS GG T + P + G G
Sbjct: 171 NTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGTG 230
Query: 330 STGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES--SVSGSTGQWH 387
S+G G + G + S G TG S + G+ TS S SVS G
Sbjct: 231 SSGLKLGAGKGDAAFGFEVSDSNSFGDTGI-----SSKTVEGNQTSSSGGSVSIDLG--- 282
Query: 388 SESGSFRPDSP----GSGNARPNNPDWGT----FEEVSGNVSPGT 424
SFR ++ GS N+ N D G E+ GN G+
Sbjct: 283 --DTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS 325
>gi|239750277 PREDICTED: hypothetical protein XP_002347351 [Homo
sapiens]
Length = 2134
Score = 57.4 bits (137), Expect = 4e-08
Identities = 89/340 (26%), Positives = 132/340 (38%), Gaps = 41/340 (12%)
Query: 265 GGNEITRGGSTSYGTGSETESPR----NPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
GG + G+ S T +PR P+ G G +GPG+T + + G S G+ T
Sbjct: 1777 GGVDAATTGAASENTSERAGTPRVSGATPAVGGGSTPGEAGPGATVSGSTGVS--AGSIT 1834
Query: 321 WKPGSSGPGSTGSWNSGSSG------TGSTGNQNPGSPRPGSTG-TWNPGSSERGSAGHW 373
PG+S S S SG++G TG+T ++ S G +G T S GS
Sbjct: 1835 ASPGASATSSESS-KSGTTGPSVGGKTGATSSEATSS--EGMSGVTGQSLGSTAGSDSEI 1891
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGS-GNARPNNPDWGTFEEVSGNVSPGTRREYHTEK 432
T+++S +GS S G SPGS G+ +WG + G E +
Sbjct: 1892 TAKTSFTGS-----SPPGKLTRPSPGSPGHFSGGTTEWGNV------ATTGAAGENTSGA 1940
Query: 433 LVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCP 492
L +++G E T SG+T T + T + G V+ GS P
Sbjct: 1941 LGSTEGSVEATT---SAGSGNTAGTSGTGDTGPGNTAV--SGTPVVSPGATPGAPGSSTP 1995
Query: 493 EAMDLGTLS-GIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSES 551
D+G S G G AF T SP+ T++ + +
Sbjct: 1996 GEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPV----SKHTDAASATA 2051
Query: 552 GIFTNTKESSSHHPGIAEFPSRGK-SSSYSKQFTSSTSYN 590
+ +K + PG A S GK +S +S TS+ S N
Sbjct: 2052 VTISGSKPGTPGTPGGA--TSGGKITSGWSSSGTSTGSSN 2089
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSG 314
P ++ PG GG+T +G + T + +S ++ S +T + ++G
Sbjct: 1902 PPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAG 1961
Query: 315 TGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGH 372
T GT +GPG+T + G+T PGS PG N + G +GH
Sbjct: 1962 TSGTG-----DTGPGNTAVSGTPVVSPGATPGA-PGSSTPGEADIGNTSFGKSGKSGH 2013
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/212 (26%), Positives = 78/212 (36%), Gaps = 26/212 (12%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313
P +E PG E G+ ++P AG + + SS G + P S
Sbjct: 46 PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 100
Query: 314 --GTGGTATWKPGSSGPGS--------TGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362
G G A K G S G + GSS +G + + P S G+TG
Sbjct: 101 GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 160
Query: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422
S ER AG+ SE S + ST + S SG + WG +E VS
Sbjct: 161 KSRERWDAGNSRSEDSPADSTNTRYGAGFS------SSGASLDVGFGWGISDEKGLEVSK 214
Query: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGST 454
RE S G + + G + V +GS+
Sbjct: 215 ADGRETRGS---GSAGGETIVFGPDAVGTGSS 243
Score = 37.7 bits (86), Expect = 0.033
Identities = 52/223 (23%), Positives = 78/223 (34%), Gaps = 34/223 (15%)
Query: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346
+SGS+ G GN + G G G ++ + G SSG GSS TG
Sbjct: 464 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 523
Query: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPN 406
S P G +PGS S G+ S S SG G+ E G G+
Sbjct: 524 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG------VGASGLNEF 577
Query: 407 NPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRT---GKEKVTSGSTTTTRRSCSK 463
+ E ++ T + T ++ E+ T G K +G SC
Sbjct: 578 GETGLSGSEKGSHIPEATPKYSETNAII-----GEISTWSKGAYKSFNGRIFFFESSCPY 632
Query: 464 TVTKTVIGPDG-----------HKEVTKEVVTSEDGSDCPEAM 495
T + I G +++ + + S+ DCP A+
Sbjct: 633 TFCRHCIESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAV 675
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338
TG + +P AG+ + GS S GN SG+GG G G SG
Sbjct: 521 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 574
Query: 339 SGTGSTG--NQNPGSPRPGSTGTWNPGSSERGSAGHWT 374
+ G TG GS P +T ++ ++ G W+
Sbjct: 575 NEFGETGLSGSEKGSHIPEATPKYSETNAIIGEISTWS 612
Score = 29.6 bits (65), Expect = 9.0
Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSG---PGSTGNRNPGSSGTGG-TATWKPGSSGPG 329
+T YG G + G S G + G GS GG T + P + G G
Sbjct: 182 NTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGTG 241
Query: 330 STGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES--SVSGSTGQWH 387
S+G G + G + S G TG S + G+ TS S SVS G
Sbjct: 242 SSGLKLGAGKGDAAFGFEVSDSNSFGDTGI-----SSKTVEGNQTSSSGGSVSIDLG--- 293
Query: 388 SESGSFRPDSP----GSGNARPNNPDWGT----FEEVSGNVSPGT 424
SFR ++ GS N+ N D G E+ GN G+
Sbjct: 294 --DTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS 336
>gi|67782356 corneodesmosin precursor [Homo sapiens]
Length = 529
Score = 57.0 bits (136), Expect = 5e-08
Identities = 62/194 (31%), Positives = 87/194 (44%), Gaps = 31/194 (15%)
Query: 275 TSYGTGSETESPRNPSSAGSWNSG--SSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTG 332
T G S S SS+GS S SSG GS+G+ + S GG+A GS PG+
Sbjct: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSA----GSFKPGTGY 112
Query: 333 SWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAG-HWTSESSVSGSTGQWHSESG 391
S S SSG+GS+ GS + GS+ SS GS+G H S SS S S+ + S
Sbjct: 113 SQVSYSSGSGSSLQGASGSSQLGSS------SSHSGSSGSHSGSSSSHSSSSSSFQFSSS 166
Query: 392 SFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTS 451
SF+ G+G+A P N + ++ + PG V+S G
Sbjct: 167 SFQ---VGNGSALPTNDN--SYRGILNPSQPGQSSSSSQTFGVSSSGQ------------ 209
Query: 452 GSTTTTRRSCSKTV 465
S ++ +R CS +
Sbjct: 210 -SVSSNQRPCSSDI 222
Score = 44.3 bits (103), Expect = 4e-04
Identities = 49/164 (29%), Positives = 74/164 (45%), Gaps = 20/164 (12%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGP------GSTGNRNPGSSGTGGTA 319
G + G S+ G+ S S + S+G +SGSS GS G+ PG+ + +
Sbjct: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
Query: 320 TWKPGSSGPGSTGSWNSGSSG--TGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW---- 373
+ GSS G++GS GSS +GS+G+ + S S+ + SS G+
Sbjct: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
Query: 374 TSESSVSG-----STGQWHSESGSFRPDSPG---SGNARPNNPD 409
T+++S G GQ S S +F S G S N RP + D
Sbjct: 178 TNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD 221
Score = 35.0 bits (79), Expect = 0.21
Identities = 57/180 (31%), Positives = 67/180 (37%), Gaps = 42/180 (23%)
Query: 266 GNEITRGGST--------------SYGTGSETESPRNPSSAGSWN--SGSSGPGSTGNRN 309
G+ I +GGS S G+GS + S GS + SGSSG S
Sbjct: 94 GSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS----- 148
Query: 310 PGSSGTGGTATWKPGSSGPGSTGSWNSGSS----GTGSTGNQNPGSPRPGSTGTWNPGSS 365
GSS SS S+ S+ SS G GS N S R G PG S
Sbjct: 149 -GSS-----------SSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR-GILNPSQPGQS 195
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTR 425
S S S S S+ Q S PDSP SG P G + S +VS G R
Sbjct: 196 SSSSQTFGVSSSGQSVSSNQ--RPCSSDIPDSPCSGG--PIVSHSGPYIPSSHSVSGGQR 251
Score = 32.3 bits (72), Expect = 1.4
Identities = 36/119 (30%), Positives = 46/119 (38%), Gaps = 16/119 (13%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSA-------------GSWNSGSSGPGSTGN-RNP 310
GG ++ GGST S R PSS+ GS + P TG+ +
Sbjct: 375 GGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSS 434
Query: 311 GSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPG-STGTWNPGSSERG 368
SS + G +P S S+G S TG + GSP P S G GSS G
Sbjct: 435 SSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPD-GSPHPDPSAGAKPCGSSSAG 492
Score = 30.4 bits (67), Expect = 5.3
Identities = 36/122 (29%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNP----GSSGTGGTAT 320
G +++ S S +GS + S + SS+ S SS GN + +S G
Sbjct: 130 GSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNP 189
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
+PG S S+ ++ SSG + NQ P S P S + P S G + S SV
Sbjct: 190 SQPGQSS-SSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGP--YIPSSHSV 246
Query: 380 SG 381
SG
Sbjct: 247 SG 248
>gi|239744587 PREDICTED: hypothetical protein XP_002343203 [Homo
sapiens]
Length = 2134
Score = 56.6 bits (135), Expect = 7e-08
Identities = 68/249 (27%), Positives = 100/249 (40%), Gaps = 33/249 (13%)
Query: 265 GGNEITRGGSTSYGTGSETESPR----NPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
GG + G+ S T +PR P+ G G +GPG+T + + G S G+ T
Sbjct: 1777 GGVDAATTGAASENTSERAGTPRVSGETPAVGGGSTPGEAGPGATVSGSTGVS--AGSIT 1834
Query: 321 WKPGSSGPGSTGSWNSGSSG------TGSTGNQNPGSPRPGSTG-TWNPGSSERGSAGHW 373
PG+S S S SG++G TG+T ++ S G +G T S GS
Sbjct: 1835 ASPGASATSSESS-KSGTTGPSVGGKTGATSSEATSS--EGMSGVTGQSLGSTAGSDSEI 1891
Query: 374 TSESSVSGSTGQWHSESGSFRPDSPGS-GNARPNNPDWGTFEEVSGNVSPGTRREYHTEK 432
T+++S +GS S G SPGS G+ +WG + G E +
Sbjct: 1892 TAKTSFTGS-----SPPGKLTRPSPGSPGHFSGGTTEWGNV------ATTGAAGENTSGA 1940
Query: 433 LVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCP 492
L +++G E T SG+T T + T + G V+ GS P
Sbjct: 1941 LGSTEGSVEATT---SAGSGNTAGTSGTGDTGPGNTAV--SGTPVVSPGATPGAPGSSTP 1995
Query: 493 EAMDLGTLS 501
D+G S
Sbjct: 1996 GEADIGNTS 2004
Score = 49.3 bits (116), Expect = 1e-05
Identities = 66/242 (27%), Positives = 96/242 (39%), Gaps = 32/242 (13%)
Query: 273 GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSG--TGGTATW----KPGSS 326
G T GS S ++ S+ +GSS PG +PGS G +GGT W G++
Sbjct: 1875 GVTGQSLGSTAGSDSEITAKTSF-TGSSPPGKLTRPSPGSPGHFSGGTTEWGNVATTGAA 1933
Query: 327 GPGSTGSWNS--------------GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGH 372
G ++G+ S ++GT TG+ PG+ T +PG++ G+ G
Sbjct: 1934 GENTSGALGSTEGSVEATTSAGSGNTAGTSGTGDTGPGNTAVSGTPVVSPGATP-GAPGS 1992
Query: 373 WTSESSVSGSTGQWHSESGSFRPDSPGSGNAR--PNNPDWGTFEEVSGNVSPGTRREYHT 430
T + G+T +SG DS N P S VS T + +
Sbjct: 1993 STPGEADIGNTS--FGKSGKSGHDSLTVLNPAFLRRTPTVSAASTTSSPVSKHT--DAAS 2048
Query: 431 EKLVTSKGDKELRTGKE-KVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGS 489
VT G K G TSG T+ S S T T P E++K + ++GS
Sbjct: 2049 ATAVTISGSKPGTPGTPGGATSGGKITSGWSSSGTSTGASNTPG---EISKALKGHKNGS 2105
Query: 490 DC 491
C
Sbjct: 2106 QC 2107
Score = 42.0 bits (97), Expect = 0.002
Identities = 30/118 (25%), Positives = 49/118 (41%), Gaps = 6/118 (5%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSG 314
P ++ PG GG+T +G + T + +S ++ S +T + ++G
Sbjct: 1902 PPGKLTRPSPGSPGHFSGGTTEWGNVATTGAAGENTSGALGSTEGSVEATTSAGSGNTAG 1961
Query: 315 TGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGH 372
T GT +GPG+T + G+T PGS PG N + G +GH
Sbjct: 1962 TSGTG-----DTGPGNTAVSGTPVVSPGATPGA-PGSSTPGEADIGNTSFGKSGKSGH 2013
Score = 40.8 bits (94), Expect = 0.004
Identities = 56/212 (26%), Positives = 78/212 (36%), Gaps = 26/212 (12%)
Query: 255 PQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS- 313
P +E PG E G+ ++P AG + + SS G + P S
Sbjct: 46 PLFSLEFGSPGETEDKSRQRQDAGSPKSEDTP-----AGGFFNSSSSSGDSDRTKPFFSL 100
Query: 314 --GTGGTATWKPGSSGPGS--------TGSWNSGSSGTGSTGNQNP-GSPRPGSTGTWNP 362
G G A K G S G + GSS +G + + P S G+TG
Sbjct: 101 GLGAPGKAEDKSGDSQDAGGSKSEDTPPGGFFYGSSSSGDSDKKKPLFSFEFGATGEDED 160
Query: 363 GSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSP 422
S ER AG+ SE S + ST + S SG + WG +E VS
Sbjct: 161 KSRERWDAGNSRSEDSPADSTNTRYGAGFS------SSGASLDVGFGWGISDEKGLEVSK 214
Query: 423 GTRREYHTEKLVTSKGDKELRTGKEKVTSGST 454
RE S G + + G + V +GS+
Sbjct: 215 ADGRETRGS---GSAGGETIVFGPDAVGTGSS 243
Score = 37.7 bits (86), Expect = 0.033
Identities = 52/223 (23%), Positives = 78/223 (34%), Gaps = 34/223 (15%)
Query: 296 NSGSSGPGSTGNRNPGSSGTG-GTATWKPG---SSGPGSTGSWNSGSSGT-----GSTGN 346
+SGS+ G GN + G G G ++ + G SSG GSS TG
Sbjct: 464 DSGSNQSGDNGNSSKDFDGNGVGDSSARNGFENSSGISEDSGVILGSSDQHEVELSRTGG 523
Query: 347 QNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPN 406
S P G +PGS S G+ S S SG G+ E G G+
Sbjct: 524 NRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGGGGKSADELG------VGASGLNEF 577
Query: 407 NPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRT---GKEKVTSGSTTTTRRSCSK 463
+ E ++ T + T ++ E+ T G K +G SC
Sbjct: 578 GETGLSGSEKGSHIPEATPKYSETNAII-----GEISTWSKGAYKSFNGRIFFFESSCPY 632
Query: 464 TVTKTVIGPDG-----------HKEVTKEVVTSEDGSDCPEAM 495
T + I G +++ + + S+ DCP A+
Sbjct: 633 TFCRHCIESGGDFNIEIKRNNDRQDINEHIANSKIPGDCPNAV 675
Score = 35.0 bits (79), Expect = 0.21
Identities = 27/98 (27%), Positives = 39/98 (39%), Gaps = 8/98 (8%)
Query: 279 TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338
TG + +P AG+ + GS S GN SG+GG G G SG
Sbjct: 521 TGGNRKRSSDPDEAGNLSPGSDVSDSGGNTWSSDSGSGG------GGKSADELGVGASGL 574
Query: 339 SGTGSTG--NQNPGSPRPGSTGTWNPGSSERGSAGHWT 374
+ G TG GS P +T ++ ++ G W+
Sbjct: 575 NEFGETGLSGSEKGSHIPEATPKYSETNAIIGEISTWS 612
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/120 (23%), Positives = 48/120 (40%), Gaps = 10/120 (8%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGS 325
G + G+T GS T + + SG SG S NP T + +
Sbjct: 1977 GTPVVSPGATPGAPGSSTPGEADIGNTSFGKSGKSGHDSLTVLNPAFLRRTPTVSAASTT 2036
Query: 326 SGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGS--AGHWTSESSVSGST 383
S P S + + ++ +G+ +PG+ GT PG + G W+S + +G++
Sbjct: 2037 SSPVSKHTDAASATAVTISGS------KPGTPGT--PGGATSGGKITSGWSSSGTSTGAS 2088
Score = 29.6 bits (65), Expect = 9.0
Identities = 46/165 (27%), Positives = 61/165 (36%), Gaps = 24/165 (14%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSG---PGSTGNRNPGSSGTGG-TATWKPGSSGPG 329
+T YG G + G S G + G GS GG T + P + G G
Sbjct: 182 NTRYGAGFSSSGASLDVGFGWGISDEKGLEVSKADGRETRGSGSAGGETIVFGPDAVGTG 241
Query: 330 STGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES--SVSGSTGQWH 387
S+G G + G + S G TG S + G+ TS S SVS G
Sbjct: 242 SSGLKLGAGKGDAAFGFEVSDSNSFGDTGI-----SSKTVEGNQTSSSGGSVSIDLG--- 293
Query: 388 SESGSFRPDSP----GSGNARPNNPDWGT----FEEVSGNVSPGT 424
SFR ++ GS N+ N D G E+ GN G+
Sbjct: 294 --DTSFRSENQFVGGGSLNSISNLWDSGQEGFGINEIGGNGMSGS 336
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 56.2 bits (134), Expect = 9e-08
Identities = 68/289 (23%), Positives = 118/289 (40%), Gaps = 30/289 (10%)
Query: 127 YNRVSEDLRSRIEVLKRKVIEKVQ-----HIQLLQKNVRAQLVDMKRLEVDIDIKIRSCR 181
Y +++ + E L E++Q H L K ++ ++ ++ R+ + +I +
Sbjct: 356 YEEIAQRSKEEAEALYHSKYEELQVTVGRHGDSL-KEIKIEISELNRVIQRLQGEIAHVK 414
Query: 182 GSCSRALAREVD--------LKDYEDQQKQLEQVI--AKDLLPSRDRQHLPLIKMKPVPD 231
C D LKD ++ LE+ + AK+ L R + L+ +K D
Sbjct: 415 KQCKNVQDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALD 474
Query: 232 LVPGNFKSQLQ----KVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPR 287
+ ++ L+ ++ + + + + ++ GGS G+ S
Sbjct: 475 VEIATYRKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSS 534
Query: 288 NPSSAGSWN--SGS-SGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGST 344
SS GS SGS G G G+ + G G+GG + + GS G GS + G G+G
Sbjct: 535 GSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGG 594
Query: 345 GNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSF 393
+ + G R GS+ GS GS SSV GS+G+ S +F
Sbjct: 595 KHSSGGGSRGGSSSGGGYGSGGGGS-------SSVKGSSGEAFGSSVTF 636
Score = 36.2 bits (82), Expect = 0.096
Identities = 29/92 (31%), Positives = 37/92 (40%), Gaps = 5/92 (5%)
Query: 314 GTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
G+GG + G GS+ S+ SG +GS G G G GS R +G
Sbjct: 520 GSGGRGSSSGGGYSSGSS-SYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGG 578
Query: 374 TSESSVS----GSTGQWHSESGSFRPDSPGSG 401
+ S+S GS G HS G R S G
Sbjct: 579 SKGGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610
Score = 31.2 bits (69), Expect = 3.1
Identities = 37/123 (30%), Positives = 44/123 (35%), Gaps = 8/123 (6%)
Query: 261 LERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTAT 320
L R GG GG +G+ S S + S G G G+ G G GG
Sbjct: 43 LSRHGGGGGGFGGG-GFGSRSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGG--- 98
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGST-GTWNPGSSERGSAGHWTSESSV 379
GSS G +G G G G G + G PG G PG G E SV
Sbjct: 99 ---GSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSV 155
Query: 380 SGS 382
+ S
Sbjct: 156 NQS 158
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 55.8 bits (133), Expect = 1e-07
Identities = 80/365 (21%), Positives = 125/365 (34%), Gaps = 32/365 (8%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGS- 330
G ST+ + S T S ++ S +S +S ST + S+ + G +T S S
Sbjct: 131 GASTATNSDSSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSS 190
Query: 331 -----TGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG--ST 383
T S +S +S ST + GT S S+G T+ +S S S+
Sbjct: 191 RASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSS 250
Query: 384 GQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELR 443
G + + S G+G A + S VS G ++E S G
Sbjct: 251 GAGTATNSESSTTSSGAGTATNSE---------SSTVSSGISTVTNSESSTPSSGANTAT 301
Query: 444 TGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGI 503
+ TS T S S T + + T TS S + T SG
Sbjct: 302 NSESSTTSSGANTATNSDSSTTSSGASTATNSESST----TSSGASTATNSESSTTSSGA 357
Query: 504 GTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSH 563
T T S T S + +ES + SG T T SS
Sbjct: 358 STATNSGSSTTSSGTSTATNSESSTVSSGAST-----ATTSESSTTSSGASTATNSESS- 411
Query: 564 HPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGH 623
S +++ S+ T+S+ N ++ S + + A H +HS
Sbjct: 412 -----TVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAV 466
Query: 624 AKSRP 628
++++P
Sbjct: 467 SEAKP 471
Score = 55.8 bits (133), Expect = 1e-07
Identities = 70/311 (22%), Positives = 120/311 (38%), Gaps = 27/311 (8%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGS 333
+TS G G+ T S + +S+G+ ++ ++ ST + G++ ++T G+ G +
Sbjct: 217 TTSNGAGTATNSESSTTSSGA-STATNSESSTPSSGAGTATNSESSTTSSGA-GTATNSE 274
Query: 334 WNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES----SVSGSTGQWHSE 389
++ SSG + N +P G+ N SS S + + S + SG++ +SE
Sbjct: 275 SSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTATNSE 334
Query: 390 SGSFRPDSPGSGNARPNNPDWGTFEEV---SGNVSPGTRREYHTEKLVTSKGDKELRTGK 446
S + + + N+ + G S S GT ++E S G T +
Sbjct: 335 SSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGASTATTSE 394
Query: 447 EKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGT- 505
TS +T S S TV+ + T TS + + T +G GT
Sbjct: 395 SSTTSSGASTATNSESSTVSSGASTATNSESST----TSSGANTATNSGSSVTSAGSGTA 450
Query: 506 -LDGFR-HRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIF--------- 554
L G H A + G P + L VS + G +G+F
Sbjct: 451 ALTGMHTTSHSASTAVSEAKPGGSLVP--WEIFLITLVSVVAAVGLFAGLFFCVRNSLSL 508
Query: 555 TNTKESSSHHP 565
NT ++ +HP
Sbjct: 509 RNTFNTAVYHP 519
Score = 54.7 bits (130), Expect = 3e-07
Identities = 86/387 (22%), Positives = 138/387 (35%), Gaps = 35/387 (9%)
Query: 274 STSYGTGSETESPRNPSSAG------SWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSG 327
+TS G + T S + S+G S +S +S ST + S+ + G +T S
Sbjct: 82 TTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSS 141
Query: 328 PGSTGS---WNSGSSGTGS-----TGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
S+G+ NS SS T S T +++ + ST T + S+ A T+ S
Sbjct: 142 TTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESS 201
Query: 380 SGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGD 439
+ S+G + + R S G+G A + S S G ++E S G
Sbjct: 202 TTSSGASTATNSESRTTSNGAGTATNSE---------SSTTSSGASTATNSESSTPSSGA 252
Query: 440 KELRTGKEKVTSGSTTTTRRSCSKTVT---KTVIGPD-------GHKEVTKEVVTSEDGS 489
+ TS T S S TV+ TV + + E T+ G+
Sbjct: 253 GTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGA 312
Query: 490 DCPEAMDLGTL-SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRG 548
+ D T SG T A T S T S S T S
Sbjct: 313 NTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSSGT 372
Query: 549 SESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAG 608
S + ++ SS S S + + + S++ + G ST +
Sbjct: 373 STATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGA 432
Query: 609 SEADHEGTHSTKRGHAKSRPVRGIHTS 635
+ A + G+ T G + + + G+HT+
Sbjct: 433 NTATNSGSSVTSAG-SGTAALTGMHTT 458
Score = 51.6 bits (122), Expect = 2e-06
Identities = 84/349 (24%), Positives = 128/349 (36%), Gaps = 35/349 (10%)
Query: 273 GSTSYGTGSE--TESPRNPSSAGSWNSGSSGPGSTGNR---------NPGSSG--TGGTA 319
GS+ +G+ T S + +S+G + SG T N + SSG T +
Sbjct: 34 GSSVISSGASTATNSGSSVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNS 93
Query: 320 TWKPGSSGPG-STGSWNS-GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES 377
+ SSG +T S +S SSG + N +P G++ N SS S+G T+ +
Sbjct: 94 EFSTVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTT-SSGASTATN 152
Query: 378 SVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTF--------EEVSGNVSPGTRREYH 429
S S +T S + + + SG + N + T S S G +
Sbjct: 153 SDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTATN 212
Query: 430 TEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGS 489
+E TS G + TS +T S S T + G ++ TS
Sbjct: 213 SESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGA----GTATNSESSTTSSGAG 268
Query: 490 DCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGS 549
+ SGI T+ P A T S T + + ++S +
Sbjct: 269 TATNSESSTVSSGISTVTNSESSTPSSGANTATNSESST-----TSSGANTATNSDSSTT 323
Query: 550 ESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFES 598
SG T T SS A + +SS+ S +ST+ N G ST S
Sbjct: 324 SSGASTATNSESSTTSSGASTATNSESSTTSS--GASTATNSGSSTTSS 370
Score = 48.5 bits (114), Expect = 2e-05
Identities = 60/223 (26%), Positives = 87/223 (39%), Gaps = 29/223 (13%)
Query: 270 TRGGSTSYGTGSETESPRNPSSAGS---WNSGSSGPGSTGNR------NPGSSGTGGTAT 320
+ +TS G G+ T S + S+G NS SS P S N + SSG
Sbjct: 258 SESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATN 317
Query: 321 WKPGSSGPGSTGSWNSGSSGTGSTG----NQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
++ G++ + NS SS T S N + G++ N GSS S+G T+
Sbjct: 318 SDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTT-SSGTSTAT 376
Query: 377 SSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTS 436
+S S + S + + + SG + N + S VS G ++E TS
Sbjct: 377 NSESSTVSSGASTATTSESSTTSSGASTATNSE-------SSTVSSGASTATNSESSTTS 429
Query: 437 KGDKELRTGKEKVTS-GSTT-------TTRRSCSKTVTKTVIG 471
G VTS GS T TT S S V++ G
Sbjct: 430 SGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVSEAKPG 472
Score = 47.4 bits (111), Expect = 4e-05
Identities = 78/350 (22%), Positives = 129/350 (36%), Gaps = 40/350 (11%)
Query: 283 TESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTG 342
T S +SA + +S S ST + S + G +T ++ GS+ + N S T
Sbjct: 22 TNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVST----ATISGSSVTSNGVSIVTN 77
Query: 343 STGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGN 402
S + + ++ SS A + S ++ SG++ +SES +P SG
Sbjct: 78 SEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSES-----STPSSGA 132
Query: 403 ARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCS 462
+ N D S S G +++ TS + TS +T S S
Sbjct: 133 STATNSD-------SSTTSSGASTATNSDSSTTSSEASTATNSESSTTSSGASTATNSES 185
Query: 463 KTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDT 522
TV+ + T TS S + T +G GT A T
Sbjct: 186 STVSSRASTATNSESST----TSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTAT 241
Query: 523 ASTGKTFPGFFSPMLGEFV---SETESRGSESGIFTNTKESSSHHPGI-------AEFPS 572
S T P G SE+ + S +G TN+ ESS+ GI + PS
Sbjct: 242 NSESST------PSSGAGTATNSESSTTSSGAGTATNS-ESSTVSSGISTVTNSESSTPS 294
Query: 573 RGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRG 622
G +++ + + ++++S G +T + S A + + +T G
Sbjct: 295 SGANTATNSESSTTSS---GANTATNSDSSTTSSGASTATNSESSTTSSG 341
Score = 42.0 bits (97), Expect = 0.002
Identities = 36/141 (25%), Positives = 59/141 (41%), Gaps = 3/141 (2%)
Query: 265 GGNEITRGGS--TSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
G N T S TS G + T S + +S+G+ + +S +T + ++ +G + T
Sbjct: 311 GANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNSGSSTTSS 370
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGS 382
S+ S S S + T +T + S + + G++ SESS + S
Sbjct: 371 GTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSS 430
Query: 383 TGQWHSESGSFRPDSPGSGNA 403
+ SGS S GSG A
Sbjct: 431 GANTATNSGS-SVTSAGSGTA 450
>gi|110618248 mucin and cadherin-like isoform 1 [Homo sapiens]
Length = 845
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/192 (28%), Positives = 82/192 (42%), Gaps = 30/192 (15%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSG-------PGSTGNRNPGSSGTGG------T 318
GG+T T + +E PR P + ++ SSG P T R P SS GG +
Sbjct: 468 GGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPPGAENS 527
Query: 319 ATWKPGSSGPGSTGSWNSGSS-----GTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHW 373
+ +P + G + + G+S G G++ + P +P G+ T PG+S+
Sbjct: 528 TSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMG 587
Query: 374 TSES----SVSGSTGQWHSESGSFRPDSPGSGNA---RPNNPDWGTFEEVSGNVSPGTRR 426
TS S + G T Q E+G+ +P PG G + +P P GT + PGT +
Sbjct: 588 TSTSHQPATPGGGTAQ-TPEAGTSQPMPPGMGTSTSHQPTTPGGGTAQ----TPEPGTSQ 642
Query: 427 EYHTEKLVTSKG 438
K S G
Sbjct: 643 PMPLSKSTPSSG 654
Score = 32.3 bits (72), Expect = 1.4
Identities = 32/107 (29%), Positives = 45/107 (42%), Gaps = 9/107 (8%)
Query: 278 GTGSETE-SPRNPS--SAGSWNSGSSGP-----GSTGNRNPGSSGTGGTATWKPGSSGPG 329
G G+ T P PS +A + G+S P G++ + P + G G T + G+S P
Sbjct: 554 GVGTSTSHQPATPSGGTAQTPEPGTSQPMPPSMGTSTSHQPATPGGGTAQTPEAGTSQPM 613
Query: 330 STGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSE 376
G S S + G +P PG T P S S+G SE
Sbjct: 614 PPGMGTSTSHQPTTPGGGTAQTPEPG-TSQPMPLSKSTPSSGGGPSE 659
Score = 31.2 bits (69), Expect = 3.1
Identities = 29/120 (24%), Positives = 44/120 (36%), Gaps = 22/120 (18%)
Query: 323 PGSSGPGSTGSWNSGSS----------GTGSTGNQNPGSPRPGSTGTWNPGSSER----- 367
P G+TG W S +S G +T + P P S T P +S
Sbjct: 463 PSPEAGGTTGPWTSTTSEVPRPPEPSQGPSTTSSGGGTGPHPPSGTTLRPPTSSTPGGPP 522
Query: 368 GSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNA---RPNNPDWGTFEEVSGNVSPGT 424
G+ + + + G + G+ +P PG G + +P P GT + PGT
Sbjct: 523 GAENSTSHQPATPGGDTAQTPKPGTSQPMPPGVGTSTSHQPATPSGGTAQ----TPEPGT 578
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 54.3 bits (129), Expect = 3e-07
Identities = 67/276 (24%), Positives = 97/276 (35%), Gaps = 58/276 (21%)
Query: 128 NRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRA 187
NRV + LRS I+ +K+++ Q I ++ L D K
Sbjct: 402 NRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKN------------------- 442
Query: 188 LAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPE 247
L D ED +Q ++ +A+ L R + L+ K DL +++ L+
Sbjct: 443 -----KLNDLEDALQQAKEDLARLL-----RDYQELMNTKLALDLEIATYRTLLE----- 487
Query: 248 WKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGN 307
G E G + + S G GS G G G
Sbjct: 488 ------------------GEESRMSGECAPNVSVSVSTSHTTISGG----GSRGGGGGGY 525
Query: 308 RNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSER 367
+ GSS G ++ G G G GS+ SG S GS G G G++ GSS
Sbjct: 526 GSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSG 585
Query: 368 GSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNA 403
G G S GS+G S GS G G++
Sbjct: 586 GYRG--GSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619
Score = 43.5 bits (101), Expect = 6e-04
Identities = 31/85 (36%), Positives = 38/85 (44%), Gaps = 2/85 (2%)
Query: 265 GGNEITRGGSTSYGTGSETE-SPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
GG G +SYG+G + S GS+ SGSS G G G G+ G
Sbjct: 547 GGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGG 606
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQN 348
GSSG GS G S S G S+G +
Sbjct: 607 GSSG-GSIGGRGSSSGGVKSSGGSS 630
Score = 35.0 bits (79), Expect = 0.21
Identities = 25/87 (28%), Positives = 27/87 (31%), Gaps = 3/87 (3%)
Query: 269 ITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328
+ GGS S R G + G G G G G G GG G G
Sbjct: 68 VNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGF---GGFGS 124
Query: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPG 355
G G G G G G P P G
Sbjct: 125 GGGGFGGGGFGGGGYGGGYGPVCPPGG 151
Score = 30.8 bits (68), Expect = 4.0
Identities = 28/94 (29%), Positives = 31/94 (32%), Gaps = 7/94 (7%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWN-------SGSSGPGSTGNRNPGSSGTGGTATWKPG 324
GG S+G G S + GS + G G G G G G GG G
Sbjct: 51 GGGGSFGAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG 110
Query: 325 SSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTG 358
G G G GS G G G G G G
Sbjct: 111 GGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYG 144
>gi|4826734 fusion (involved in t(12;16) in malignant liposarcoma)
[Homo sapiens]
Length = 526
Score = 52.8 bits (125), Expect = 1e-06
Identities = 42/162 (25%), Positives = 59/162 (36%), Gaps = 12/162 (7%)
Query: 274 STSYGTGSETESPRNPSSAGSWNS-----GSSGPGSTGNRNPGSSGTGGTATWKPGSSGP 328
S+SYG + PS G S + P G +N +S +GG G G
Sbjct: 119 SSSYGQPQSGSYSQQPSYGGQQQSYGQQQSYNPPQGYGQQNQYNSSSGGGG----GGGGG 174
Query: 329 GSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
G+ G S S G +G + G G+ G +RG G S G G ++
Sbjct: 175 GNYGQDQSSMSSGGGSGGGYGNQDQSGGGGSGGYGQQDRGGRGRGGSGGGGGGGGGGYNR 234
Query: 389 ESGSFRPDSPG---SGNARPNNPDWGTFEEVSGNVSPGTRRE 427
SG + P G G D G F + G G+R +
Sbjct: 235 SSGGYEPRGRGGGRGGRGGMGGSDRGGFNKFGGPRDQGSRHD 276
Score = 38.1 bits (87), Expect = 0.025
Identities = 30/108 (27%), Positives = 36/108 (33%), Gaps = 8/108 (7%)
Query: 268 EITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGG---TATWK-P 323
+ RGG G G P G + G SG G G G G GG WK P
Sbjct: 374 DFNRGG----GNGRGGRGRGGPMGRGGYGGGGSGGGGRGGFPSGGGGGGGQQRAGDWKCP 429
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAG 371
+ SW + + + PG GS N G RG G
Sbjct: 430 NPTCENMNFSWRNECNQCKAPKPDGPGGGPGGSHMGGNYGDDRRGGRG 477
Score = 37.0 bits (84), Expect = 0.056
Identities = 34/127 (26%), Positives = 44/127 (34%), Gaps = 19/127 (14%)
Query: 284 ESPRNPSSAGSWNSGSSGPG-----STGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGS 338
+ P + +A W G G S R + GG G GP G + G
Sbjct: 342 DDPPSAKAAIDWFDGKEFSGNPIKVSFATRRADFNRGGGNGRGGRGRGGPMGRGGYGGGG 401
Query: 339 SGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSES-SVSGSTGQWHSESGSF---R 394
SG G G G P G G G +R AG W + + W +E +
Sbjct: 402 SGGGGRG----GFPSGGGGG----GGQQR--AGDWKCPNPTCENMNFSWRNECNQCKAPK 451
Query: 395 PDSPGSG 401
PD PG G
Sbjct: 452 PDGPGGG 458
>gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 52.4 bits (124), Expect = 1e-06
Identities = 87/315 (27%), Positives = 121/315 (38%), Gaps = 64/315 (20%)
Query: 310 PGSSGTGGTATWKPGSSGPGSTGSWNSG---SSGTGSTGNQNPGSPRPGSTGT------- 359
PGSSGT T PGSS G+T + S TG+TG + PGS+ T
Sbjct: 17 PGSSGTISHTTVAPGSSVTGTTTGASDDQVTGSKTGTTGVALSTTVAPGSSSTEATTSTG 76
Query: 360 --------WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWG 411
G++ RGSA T S++ +T SFR G+G + + G
Sbjct: 77 VHRTTVVGQKTGATTRGSAKQGT-RSTIEATT--------SFR----GTGTT-GSGMNTG 122
Query: 412 TFEEVSGN-VSPGTRREYHTEKLVTSKGDKELRTGKEKVTSG--STTTTRRSCSKTVTKT 468
T VSGN +SP + ++TE TS + G E T+G S TT S T T
Sbjct: 123 TTGVVSGNTISPSS---FNTE--ATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATT 177
Query: 469 VIGPDGHKEVTKEVVTS-----------EDGSDCPEAMDLGTLSGIGTLDGF------RH 511
+G G E ++VT+ + + D+G +G+G G R
Sbjct: 178 SLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRS 237
Query: 512 RHPDEAAFFDTASTGKT-FPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEF 570
+ + +G T PG F G T S+ G T SS GI E
Sbjct: 238 QPTGSKTGYTVTGSGTTALPGGF--RTGNTPGSTGVTSSQEG----TTVVSSGITGIPET 291
Query: 571 PSRGKSSSYSKQFTS 585
G S S + T+
Sbjct: 292 SISGPSKEASDKTTA 306
Score = 49.7 bits (117), Expect = 8e-06
Identities = 74/255 (29%), Positives = 105/255 (41%), Gaps = 32/255 (12%)
Query: 276 SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTA---TWKPGSSGPGSTG 332
S GT S T S G+ +G+S TG++ +GT G A T PGSS +T
Sbjct: 19 SSGTISHTTVAPGSSVTGT-TTGASDDQVTGSK----TGTTGVALSTTVAPGSSSTEATT 73
Query: 333 SWNSGSSGT----GSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
S +G T TG GS + G+ T +S RG+ T +G+TG
Sbjct: 74 S--TGVHRTTVVGQKTGATTRGSAKQGTRSTIEATTSFRGTG--TTGSGMNTGTTGVVSG 129
Query: 389 ES---GSFRPDSPGSGNARPN-NPDWGTFEEVSG-NVSPGTRREYHTEKL----VTSKGD 439
+ SF ++ + RPN + GT VSG V+PG+ T L T G
Sbjct: 130 NTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATTSLGNGGTTEAGS 189
Query: 440 KELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG- 498
K + TG +T+G+T +K T T +G + + G P G
Sbjct: 190 KIVTTG---ITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRSQPTGSKTGY 246
Query: 499 TLSGIGTL---DGFR 510
T++G GT GFR
Sbjct: 247 TVTGSGTTALPGGFR 261
Score = 34.3 bits (77), Expect = 0.37
Identities = 56/201 (27%), Positives = 81/201 (40%), Gaps = 30/201 (14%)
Query: 273 GSTSYG--TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS-GTGGTA---TWKPGSS 326
G+T G TG+ N S S+N+ ++ G++ NPGS GT G T PGSS
Sbjct: 113 GTTGSGMNTGTTGVVSGNTISPSSFNTEATS-GTSERPNPGSEIGTTGIVSGTTVAPGSS 171
Query: 327 GPGSTGS-WNSGSSGTGS----TGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
+T S N G++ GS TG + PGS T S++ G A + V
Sbjct: 172 NTEATTSLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVA------TGVGM 225
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
+TG + SG +P +G V+G+ + + T S G
Sbjct: 226 ATGITNIISGRSQPTGSKTGYT------------VTGSGTTALPGGFRTGNTPGSTGVTS 273
Query: 442 LRTGKEKVTSGSTTTTRRSCS 462
+ G V+SG T S S
Sbjct: 274 SQEGTTVVSSGITGIPETSIS 294
Score = 29.6 bits (65), Expect = 9.0
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS--GPGSTGNRNPGSSGTGGTATWKP 323
G +T G+T+ G T + + S G++ G TG SG A+ K
Sbjct: 245 GYTVTGSGTTALPGGFRTGNTPGSTGVTSSQEGTTVVSSGITGIPETSISGPSKEASDKT 304
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQ 347
+ GP +T + ++G T TG Q
Sbjct: 305 TAPGPPTTVTASTGVKETSETGVQ 328
>gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens]
Length = 598
Score = 52.4 bits (124), Expect = 1e-06
Identities = 87/315 (27%), Positives = 121/315 (38%), Gaps = 64/315 (20%)
Query: 310 PGSSGTGGTATWKPGSSGPGSTGSWNSG---SSGTGSTGNQNPGSPRPGSTGT------- 359
PGSSGT T PGSS G+T + S TG+TG + PGS+ T
Sbjct: 17 PGSSGTISHTTVAPGSSVTGTTTGASDDQVTGSKTGTTGVALSTTVAPGSSSTEATTSTG 76
Query: 360 --------WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWG 411
G++ RGSA T S++ +T SFR G+G + + G
Sbjct: 77 VHRTTVVGQKTGATTRGSAKQGT-RSTIEATT--------SFR----GTGTT-GSGMNTG 122
Query: 412 TFEEVSGN-VSPGTRREYHTEKLVTSKGDKELRTGKEKVTSG--STTTTRRSCSKTVTKT 468
T VSGN +SP + ++TE TS + G E T+G S TT S T T
Sbjct: 123 TTGVVSGNTISPSS---FNTE--ATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATT 177
Query: 469 VIGPDGHKEVTKEVVTS-----------EDGSDCPEAMDLGTLSGIGTLDGF------RH 511
+G G E ++VT+ + + D+G +G+G G R
Sbjct: 178 SLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRS 237
Query: 512 RHPDEAAFFDTASTGKT-FPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEF 570
+ + +G T PG F G T S+ G T SS GI E
Sbjct: 238 QPTGSKTGYTVTGSGTTALPGGF--RTGNTPGSTGVTSSQEG----TTVVSSGITGIPET 291
Query: 571 PSRGKSSSYSKQFTS 585
G S S + T+
Sbjct: 292 SISGPSKEASDKTTA 306
Score = 49.7 bits (117), Expect = 8e-06
Identities = 74/255 (29%), Positives = 105/255 (41%), Gaps = 32/255 (12%)
Query: 276 SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTA---TWKPGSSGPGSTG 332
S GT S T S G+ +G+S TG++ +GT G A T PGSS +T
Sbjct: 19 SSGTISHTTVAPGSSVTGT-TTGASDDQVTGSK----TGTTGVALSTTVAPGSSSTEATT 73
Query: 333 SWNSGSSGT----GSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
S +G T TG GS + G+ T +S RG+ T +G+TG
Sbjct: 74 S--TGVHRTTVVGQKTGATTRGSAKQGTRSTIEATTSFRGTG--TTGSGMNTGTTGVVSG 129
Query: 389 ES---GSFRPDSPGSGNARPN-NPDWGTFEEVSG-NVSPGTRREYHTEKL----VTSKGD 439
+ SF ++ + RPN + GT VSG V+PG+ T L T G
Sbjct: 130 NTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATTSLGNGGTTEAGS 189
Query: 440 KELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG- 498
K + TG +T+G+T +K T T +G + + G P G
Sbjct: 190 KIVTTG---ITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRSQPTGSKTGY 246
Query: 499 TLSGIGTL---DGFR 510
T++G GT GFR
Sbjct: 247 TVTGSGTTALPGGFR 261
Score = 34.3 bits (77), Expect = 0.37
Identities = 56/201 (27%), Positives = 81/201 (40%), Gaps = 30/201 (14%)
Query: 273 GSTSYG--TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS-GTGGTA---TWKPGSS 326
G+T G TG+ N S S+N+ ++ G++ NPGS GT G T PGSS
Sbjct: 113 GTTGSGMNTGTTGVVSGNTISPSSFNTEATS-GTSERPNPGSEIGTTGIVSGTTVAPGSS 171
Query: 327 GPGSTGS-WNSGSSGTGS----TGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
+T S N G++ GS TG + PGS T S++ G A + V
Sbjct: 172 NTEATTSLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVA------TGVGM 225
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
+TG + SG +P +G V+G+ + + T S G
Sbjct: 226 ATGITNIISGRSQPTGSKTGYT------------VTGSGTTALPGGFRTGNTPGSTGVTS 273
Query: 442 LRTGKEKVTSGSTTTTRRSCS 462
+ G V+SG T S S
Sbjct: 274 SQEGTTVVSSGITGIPETSIS 294
Score = 29.6 bits (65), Expect = 9.0
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS--GPGSTGNRNPGSSGTGGTATWKP 323
G +T G+T+ G T + + S G++ G TG SG A+ K
Sbjct: 245 GYTVTGSGTTALPGGFRTGNTPGSTGVTSSQEGTTVVSSGITGIPETSISGPSKEASDKT 304
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQ 347
+ GP +T + ++G T TG Q
Sbjct: 305 TAPGPPTTVTASTGVKETSETGVQ 328
>gi|239744589 PREDICTED: mucin 19 [Homo sapiens]
Length = 598
Score = 52.4 bits (124), Expect = 1e-06
Identities = 87/315 (27%), Positives = 121/315 (38%), Gaps = 64/315 (20%)
Query: 310 PGSSGTGGTATWKPGSSGPGSTGSWNSG---SSGTGSTGNQNPGSPRPGSTGT------- 359
PGSSGT T PGSS G+T + S TG+TG + PGS+ T
Sbjct: 17 PGSSGTISHTTVAPGSSVTGTTTGASDDQVTGSKTGTTGVALSTTVAPGSSSTEATTSTG 76
Query: 360 --------WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWG 411
G++ RGSA T S++ +T SFR G+G + + G
Sbjct: 77 VHRTTVVGQKTGATTRGSAKQGT-RSTIEATT--------SFR----GTGTT-GSGMNTG 122
Query: 412 TFEEVSGN-VSPGTRREYHTEKLVTSKGDKELRTGKEKVTSG--STTTTRRSCSKTVTKT 468
T VSGN +SP + ++TE TS + G E T+G S TT S T T
Sbjct: 123 TTGVVSGNTISPSS---FNTE--ATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATT 177
Query: 469 VIGPDGHKEVTKEVVTS-----------EDGSDCPEAMDLGTLSGIGTLDGF------RH 511
+G G E ++VT+ + + D+G +G+G G R
Sbjct: 178 SLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRS 237
Query: 512 RHPDEAAFFDTASTGKT-FPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEF 570
+ + +G T PG F G T S+ G T SS GI E
Sbjct: 238 QPTGSKTGYTVTGSGTTALPGGF--RTGNTPGSTGVTSSQEG----TTVVSSGITGIPET 291
Query: 571 PSRGKSSSYSKQFTS 585
G S S + T+
Sbjct: 292 SISGPSKEASDKTTA 306
Score = 49.7 bits (117), Expect = 8e-06
Identities = 74/255 (29%), Positives = 105/255 (41%), Gaps = 32/255 (12%)
Query: 276 SYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTA---TWKPGSSGPGSTG 332
S GT S T S G+ +G+S TG++ +GT G A T PGSS +T
Sbjct: 19 SSGTISHTTVAPGSSVTGT-TTGASDDQVTGSK----TGTTGVALSTTVAPGSSSTEATT 73
Query: 333 SWNSGSSGT----GSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHS 388
S +G T TG GS + G+ T +S RG+ T +G+TG
Sbjct: 74 S--TGVHRTTVVGQKTGATTRGSAKQGTRSTIEATTSFRGTG--TTGSGMNTGTTGVVSG 129
Query: 389 ES---GSFRPDSPGSGNARPN-NPDWGTFEEVSG-NVSPGTRREYHTEKL----VTSKGD 439
+ SF ++ + RPN + GT VSG V+PG+ T L T G
Sbjct: 130 NTISPSSFNTEATSGTSERPNPGSEIGTTGIVSGTTVAPGSSNTEATTSLGNGGTTEAGS 189
Query: 440 KELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG- 498
K + TG +T+G+T +K T T +G + + G P G
Sbjct: 190 KIVTTG---ITTGTTIVPGSFNTKATTSTDVGVATGVGMATGITNIISGRSQPTGSKTGY 246
Query: 499 TLSGIGTL---DGFR 510
T++G GT GFR
Sbjct: 247 TVTGSGTTALPGGFR 261
Score = 34.3 bits (77), Expect = 0.37
Identities = 56/201 (27%), Positives = 81/201 (40%), Gaps = 30/201 (14%)
Query: 273 GSTSYG--TGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSS-GTGGTA---TWKPGSS 326
G+T G TG+ N S S+N+ ++ G++ NPGS GT G T PGSS
Sbjct: 113 GTTGSGMNTGTTGVVSGNTISPSSFNTEATS-GTSERPNPGSEIGTTGIVSGTTVAPGSS 171
Query: 327 GPGSTGS-WNSGSSGTGS----TGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSG 381
+T S N G++ GS TG + PGS T S++ G A + V
Sbjct: 172 NTEATTSLGNGGTTEAGSKIVTTGITTGTTIVPGSFNTKATTSTDVGVA------TGVGM 225
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKE 441
+TG + SG +P +G V+G+ + + T S G
Sbjct: 226 ATGITNIISGRSQPTGSKTGYT------------VTGSGTTALPGGFRTGNTPGSTGVTS 273
Query: 442 LRTGKEKVTSGSTTTTRRSCS 462
+ G V+SG T S S
Sbjct: 274 SQEGTTVVSSGITGIPETSIS 294
Score = 29.6 bits (65), Expect = 9.0
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 266 GNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS--GPGSTGNRNPGSSGTGGTATWKP 323
G +T G+T+ G T + + S G++ G TG SG A+ K
Sbjct: 245 GYTVTGSGTTALPGGFRTGNTPGSTGVTSSQEGTTVVSSGITGIPETSISGPSKEASDKT 304
Query: 324 GSSGPGSTGSWNSGSSGTGSTGNQ 347
+ GP +T + ++G T TG Q
Sbjct: 305 TAPGPPTTVTASTGVKETSETGVQ 328
>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
Length = 1257
Score = 49.3 bits (116), Expect = 1e-05
Identities = 51/191 (26%), Positives = 75/191 (39%), Gaps = 29/191 (15%)
Query: 216 RDRQHLPLIKMKPVPDLVPGNFKSQLQKVPPEWKALTDMPQMRMELERPGGNEITRGGST 275
R R HLP + VP +F +L P + + P L +E++ GS
Sbjct: 411 RGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLS----SEVSGSGSG 466
Query: 276 SYGTGSETESPRNPSSAG-------SWNSG----------SSGPGSTGNRNPGS--SGTG 316
++G + + +G +W SG S+G GS+ + + G+ SG G
Sbjct: 467 NFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEG 526
Query: 317 GTATWKPGSSGPGSTGSWNS-----GSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAG 371
+ GS+G GS G+ S + G GS G Q PG GS G PG G
Sbjct: 527 QGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGH-GSGGGQGPGDGHGSGGG 585
Query: 372 HWTSESSVSGS 382
+ SGS
Sbjct: 586 KNSGGGKGSGS 596
Score = 49.3 bits (116), Expect = 1e-05
Identities = 36/111 (32%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 265 GGNEITRG-GSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNR----NPGSSGTGGTA 319
GG + + G GS+S+ +G S S G GS+G GS GN+ G++G G+
Sbjct: 502 GGGQGSNGQGSSSHSSGGNQCSGEGQGSRGG--QGSNGQGSGGNQCSRDGQGTAGGHGSG 559
Query: 320 TWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSA 370
+ G GS G G G GS G +N G + +G + G ERG +
Sbjct: 560 GGQRPGGGHGSGGGQGPGD-GHGSGGGKNSGGGKGSGSGKGSDGDGERGKS 609
Score = 45.4 bits (106), Expect = 2e-04
Identities = 39/129 (30%), Positives = 53/129 (41%), Gaps = 17/129 (13%)
Query: 255 PQMRMELERPGGNEIT-------RGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGN 307
PQ + + E GG+ + G + G GS + + SS G+ SG G GS G
Sbjct: 474 PQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGE-GQGSRGG 532
Query: 308 RNPGSSGTGGTATWKPGSSGPGSTGSWNSG-----SSGTGSTGNQNPGSPRPGSTGTWNP 362
+ G+GG + G G+ G SG G GS G Q PG GS G N
Sbjct: 533 QGSNGQGSGGNQCSRDGQ---GTAGGHGSGGGQRPGGGHGSGGGQGPGDGH-GSGGGKNS 588
Query: 363 GSSERGSAG 371
G + +G
Sbjct: 589 GGGKGSGSG 597
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/138 (30%), Positives = 51/138 (36%), Gaps = 16/138 (11%)
Query: 284 ESPRNPSSAGSW--NSGSSGPGSTGNRNPGSSGTGGTATWKP--------GSSGPGSTGS 333
E+P N + S SGS G GN G + P G G GS
Sbjct: 448 EAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGS 507
Query: 334 WNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSF 393
GSS S GNQ G + GS G GS+ +GS G+ S + G H G
Sbjct: 508 NGQGSSSHSSGGNQCSGEGQ-GSRG--GQGSNGQGSGGNQCSRDGQGTAGG--HGSGGGQ 562
Query: 394 RPDSPGSGNARPNNPDWG 411
RP G G+ P G
Sbjct: 563 RPGG-GHGSGGGQGPGDG 579
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 48.9 bits (115), Expect = 1e-05
Identities = 39/127 (30%), Positives = 51/127 (40%), Gaps = 26/127 (20%)
Query: 272 GGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG-GTATWKPGSSGPGS 330
GG++ G P N SSAGSW+ S G++ GS TG G G S PG
Sbjct: 1616 GGASGQDVGGSRPGPTNQSSAGSWD-------SPGSQVSGSCWTGAGAVDQAGGCSKPGF 1668
Query: 331 TGSWNSGSSGTGSTGNQNPGSPRPGS------TGTW-----------NPGSSERGSAGHW 373
G G+ G+Q G RPGS G+W PG +++ S G W
Sbjct: 1669 EDQAIGGGFWPGA-GDQTGGGSRPGSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSW 1727
Query: 374 TSESSVS 380
+ S
Sbjct: 1728 AGTGNQS 1734
Score = 46.2 bits (108), Expect = 9e-05
Identities = 45/166 (27%), Positives = 62/166 (37%), Gaps = 25/166 (15%)
Query: 273 GSTSYGTGSETES-----PRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATW-KPGSS 326
G + GTG + P + ++ GSW G+SG G+R PG + +W PGS
Sbjct: 1588 GDSWAGTGDQASGWFCVCPGSQTNGGSWG-GASGQDVGGSR-PGPTNQSSAGSWDSPGSQ 1645
Query: 327 GPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSVSGSTGQW 386
GS W + + G PG G + PG+ ++ G S G W
Sbjct: 1646 VSGSC--WTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRPGSEDQSSGIGSW 1703
Query: 387 HSESGSFRPDSPGSGNARPNNPD------W-GTFEEVSGN--VSPG 423
G G ARP D W GT + SG + PG
Sbjct: 1704 GVAGGQV------LGGARPGPADQSSGGSWAGTGNQSSGRSWIGPG 1743
Score = 40.4 bits (93), Expect = 0.005
Identities = 48/189 (25%), Positives = 64/189 (33%), Gaps = 38/189 (20%)
Query: 272 GGSTSYGT-------GSETESPRNPSSAGSWN------------SGSSGPGS-TGNRNPG 311
GG TS GT G N +S GSW +G + GS G + G
Sbjct: 1286 GGQTSEGTWAGDKASGGAWTGAENQASGGSWALAGNQAIGELWAAGQASDGSWPGGQASG 1345
Query: 312 SSGTGGTA---TWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERG 368
S G A +W G+ S GSW +G S+ + G G+W S + G
Sbjct: 1346 VSWVGEEAIGGSWT-GAENQASEGSWAGAGAGNMSSVSYWAGVVDQAGGGSWAGTSDQSG 1404
Query: 369 SAGHWTSESSVSGSTGQWHSESGS------FRPDSPGSGNARPNNPD-------WGTFEE 415
E SG G W G P+ SG + + D G ++
Sbjct: 1405 GGSKPRFEDQASGE-GSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQ 1463
Query: 416 VSGNVSPGT 424
SG GT
Sbjct: 1464 SSGGAWAGT 1472
Score = 38.9 bits (89), Expect = 0.015
Identities = 36/145 (24%), Positives = 50/145 (34%), Gaps = 34/145 (23%)
Query: 266 GNEITRGGSTSYGT------GSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG--- 316
G+E G S+G G P + SS GSW TGN++ G S G
Sbjct: 1692 GSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSW-------AGTGNQSSGRSWIGPGD 1744
Query: 317 ---------------GTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWN 361
G +W G+ S SW G + G GS + G+W
Sbjct: 1745 QAVDCSKPEFEDQACGGGSWA-GAGSQASGESWAGSRPGNEAIGGSRMGSEDQATGGSW- 1802
Query: 362 PGSSERGSAGHWTSESSVSGSTGQW 386
SE ++G + V + G W
Sbjct: 1803 -ARSEDQASGRFQVSFEVEANEGFW 1826
Score = 37.7 bits (86), Expect = 0.033
Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 14/116 (12%)
Query: 270 TRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPG----SSGTG---GTATWK 322
+R G T+ + +SP + S W + + G PG + G G G
Sbjct: 1626 SRPGPTNQSSAGSWDSPGSQVSGSCWTGAGAVDQAGGCSKPGFEDQAIGGGFWPGAGDQT 1685
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPG-----STGTWNPGSSERGSAGHW 373
G S PGS +SG G G Q G RPG S G+W G+ + S W
Sbjct: 1686 GGGSRPGSEDQ-SSGIGSWGVAGGQVLGGARPGPADQSSGGSW-AGTGNQSSGRSW 1739
Score = 35.8 bits (81), Expect = 0.13
Identities = 91/390 (23%), Positives = 135/390 (34%), Gaps = 43/390 (11%)
Query: 262 ERPGGNEITRGGSTSYGTGSETESPRNPSSAGSW---NSGSSGPGSTGNRNPGSSGT-GG 317
E E + G+ +G P + SS SW +SG G+ + S G G
Sbjct: 1412 EDQASGEGSWAGAGGQASGGSMLGPEDQSSGRSWADTADQASGGSRLGHVDQSSGGAWAG 1471
Query: 318 TATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGS---PRPGSTGTWNPGSSERGSAGHWT 374
T G S P S G+ G GS P S+G S ++ S G
Sbjct: 1472 TLDQSGGGSKPRFENQTTEEGSWAGAGGQAGGGSKVGPEDQSSGRSWANSGDQISGGFLV 1531
Query: 375 S--ESSVSGS-TGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTE 431
+ + GS TG H S +P + R + D E+V G+ G R +
Sbjct: 1532 GIVDQANGGSWTGAGHPASVGPKPIFEDQVSGRGSWAD--AREQVVGDSRLGLRDQ---- 1585
Query: 432 KLVTSKGDKELRTGKEK-----VTSGSTT---TTRRSCSKTVTKTVIGPDGHKEVTKEVV 483
S GD TG + V GS T + + + V + GP
Sbjct: 1586 ----SSGDSWAGTGDQASGWFCVCPGSQTNGGSWGGASGQDVGGSRPGPTNQ-------- 1633
Query: 484 TSEDGSDCPEAMDLGTL-SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLG--EF 540
+S D P + G+ +G G +D + + F D A G +PG G
Sbjct: 1634 SSAGSWDSPGSQVSGSCWTGAGAVD--QAGGCSKPGFEDQAIGGGFWPGAGDQTGGGSRP 1691
Query: 541 VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
SE +S G S + PG A+ S G + Q + + GD +
Sbjct: 1692 GSEDQSSGIGSWGVAGGQVLGGARPGPADQSSGGSWAGTGNQSSGRSWIGPGDQAVDCSK 1751
Query: 601 YKMADEA--GSEADHEGTHSTKRGHAKSRP 628
+ D+A G G+ ++ A SRP
Sbjct: 1752 PEFEDQACGGGSWAGAGSQASGESWAGSRP 1781
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 48.9 bits (115), Expect = 1e-05
Identities = 87/337 (25%), Positives = 123/337 (36%), Gaps = 48/337 (14%)
Query: 264 PGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
PG + T +++ +GS ES + SS+GS ++ S PGST + G T T P
Sbjct: 3669 PGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALS-PGSTTALSFGQEST--TFHSSP 3725
Query: 324 GSSG----PGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
GS+ P ST S SG + + + GSPR T +P SS TS
Sbjct: 3726 GSTHTTLFPDSTTS--SGIVEASTRVHSSTGSPRT----TLSPASS--------TSPGLQ 3771
Query: 380 SGSTG-QWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKG 438
ST Q H S P P + A E + + SPG+ H T+ G
Sbjct: 3772 GESTAFQTHPASTHTTPSPPSTATAPVE-------ESTTYHRSPGSTPTTHFPASSTTSG 3824
Query: 439 DKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG 498
E T S TT + S T G E T ++ P + ++
Sbjct: 3825 HSEKSTIFHSSPDASGTTPSSAHSTT--------SGRGESTTSRIS-------PGSTEIT 3869
Query: 499 TLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTK 558
TL G T G + S T LG T SR +
Sbjct: 3870 TLPGSTTTPGL--SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 3927
Query: 559 ESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDST 595
+S+ PG++E + SSS T +T + R +T
Sbjct: 3928 PASTTTPGLSEESTTVYSSSPGS--TETTVFPRSTTT 3962
Score = 48.5 bits (114), Expect = 2e-05
Identities = 101/413 (24%), Positives = 151/413 (36%), Gaps = 71/413 (17%)
Query: 263 RPGGNEITR--GGSTSYGTGSE-TESPRNPSSA------GSWNSGSSGPGSTG-NRNPGS 312
RPG T G +T G E T S +P S GS + S GP ST + PGS
Sbjct: 3282 RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGS 3341
Query: 313 SGT-----GGTATWKPGSSGP--GSTGSWNSGSSGTGSTGNQNPGS------------PR 353
+ T TA+ +S P STGS ++ S GST Q + P
Sbjct: 3342 TETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPA 3401
Query: 354 PGST-------GTWNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPN 406
P +T T + GS H+++ S+ G SE + SP + P+
Sbjct: 3402 PPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLG-----RSEESTTVHSSPVATATTPS 3456
Query: 407 ---NPDWGTFEE-VSGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCS 462
+ G EE + + SPG+ + H + T+ G G+E TS S+TT S +
Sbjct: 3457 PARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSG-----RGEESTTSHSSTTHTISSA 3511
Query: 463 KTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDT 522
+ T ++ E +S + D T SG H D
Sbjct: 3512 PSTTSALV------EEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 3565
Query: 523 ASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQ 582
+ T S +LGE + S GS + T S+ PG++E + SS S
Sbjct: 3566 PARSTT-----SVLLGESTTSPISSGS---METTALPGSTTTPGLSEKSTTFHSSPRSPA 3617
Query: 583 FTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTS 635
T S + E + S + TH+T + + P H++
Sbjct: 3618 TTLSPASTTSSGVSE-------ESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663
Score = 47.4 bits (111), Expect = 4e-05
Identities = 93/366 (25%), Positives = 125/366 (34%), Gaps = 66/366 (18%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG------------GTATW 321
ST+Y + + +P SA S G S +T + +PG++GT G T
Sbjct: 4247 STTYHS-RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 4305
Query: 322 KPGSSG-------PGSTGSWNSGSSGTGSTGNQNPGSPRP--GSTGTWNPGSSERGSAGH 372
P SSG PGST + +G S +T +P SP T + G SE + H
Sbjct: 4306 SPISSGSTETTALPGSTTT--AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 4363
Query: 373 -------------WTSESSVSGSTGQWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSG 418
T+ VS + HS GS SPGS A P+ TF
Sbjct: 4364 SRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--- 4420
Query: 419 NVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEV 478
SPG+ T+ G E T T TT + S T G
Sbjct: 4421 --SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT-------RQGESTT 4471
Query: 479 TKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLG 538
+ S+D + P T S L H P +ST T S LG
Sbjct: 4472 FQSWPNSKDTTPAPPT----TTSAFVELSTTSHGSP--------SSTPTTHFSASSTTLG 4519
Query: 539 EFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQF----TSSTSYNRGDS 594
T S T + S G+ E + SS S Q S+T+ RG+
Sbjct: 4520 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEE 4579
Query: 595 TFESKS 600
+ S S
Sbjct: 4580 STTSHS 4585
Score = 47.0 bits (110), Expect = 5e-05
Identities = 95/393 (24%), Positives = 143/393 (36%), Gaps = 69/393 (17%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG------------GTATW 321
ST+Y + + +P SA S G S +T + +PG++GT G T
Sbjct: 1607 STTYHS-RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 1665
Query: 322 KPGSSG-------PGSTGSWNSGSSGTGSTGNQNPGSP---------------RPGSTGT 359
P SSG PGST + +G S +T +P SP +T
Sbjct: 1666 SPISSGSTETTALPGSTTT--AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 1723
Query: 360 WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSG 418
PGS+ + T+ VS + HS GS SPGS A P+ TF
Sbjct: 1724 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--- 1780
Query: 419 NVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEV 478
SPG+ T+ G E T T TT + S T G
Sbjct: 1781 --SPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT-------RQGESTT 1831
Query: 479 TKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDE--AAFFDTAST----GKTFPGF 532
+ +S+D P T S L H P F +ST +
Sbjct: 1832 FQSWPSSKDTMPAPPT----TTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTV 1887
Query: 533 FSPMLGEFVSETESRGSESGIFTNTKESSSHH--PGIAE---FPSRGKSSSYSKQF-TSS 586
S + + + +R + SG+ +ES+++H PG + FP +S S++ TS
Sbjct: 1888 HSSPVATATTPSPARSTTSGL---VEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSH 1944
Query: 587 TSYNRGDSTFESKSYKMADEAGSEADHEGTHST 619
+S S+ S + + +E S G+ +T
Sbjct: 1945 SSTTHTISSPPSTTSALVEEPTSYHSSPGSTAT 1977
Score = 46.2 bits (108), Expect = 9e-05
Identities = 87/348 (25%), Positives = 127/348 (36%), Gaps = 53/348 (15%)
Query: 264 PGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKP 323
PG + T +++ +G ES + SS+GS ++ S PGST + G T T P
Sbjct: 1029 PGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALS-PGSTTALSFGQEST--TFHSNP 1085
Query: 324 GSSG----PGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSSERGSAGHWTSESSV 379
GS+ P ST S SG + + + GSPR T +P SS TS
Sbjct: 1086 GSTHTTLFPDSTTS--SGIVEASTRVHSSTGSPRT----TLSPASS--------TSPGLQ 1131
Query: 380 SGSTG-QWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKG 438
ST Q H S P P + A E + + SPG+ H T+ G
Sbjct: 1132 GESTAFQTHPASTHTTPSPPSTATAPVE-------ESTTYHRSPGSTPTTHFPASSTTSG 1184
Query: 439 DKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG 498
E T S TT + S T G E T ++ P + ++
Sbjct: 1185 HSEKSTIFHSSPDASGTTPSSAHSTT--------SGRGESTTSRIS-------PGSTEIT 1229
Query: 499 TLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSETESRGSESGIFTNTK 558
TL G T G + S T LG T SR +
Sbjct: 1230 TLPGSTTTPGL--SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVS 1287
Query: 559 ESSSHHPGIAE------FPSRGKSSSYSKQFTSSTS-YNRGDSTFESK 599
+S+ PG++E SRG + + +++TS + +TF S+
Sbjct: 1288 PASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSR 1335
Score = 45.8 bits (107), Expect = 1e-04
Identities = 96/357 (26%), Positives = 130/357 (36%), Gaps = 56/357 (15%)
Query: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSG----PGSTGSWNSGSS 339
ES +P S+GS + ++ PGST PG S T P S P ST S SG S
Sbjct: 3577 ESTTSPISSGSMET-TALPGST--TTPGLSEKSTTFHSSPRSPATTLSPASTTS--SGVS 3631
Query: 340 GTGSTGNQNPGSPR----PGSTGT-----------WNPGSSERGSAGHWTSESSVSGSTG 384
+T + PGS P ST T +PGS++ T+ S S +
Sbjct: 3632 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQEST 3691
Query: 385 QWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELR 443
HS SGS SPGS A + TF SPG+ TS G E
Sbjct: 3692 TSHSSSGSTDTALSPGSTTALSFGQESTTFHS-----SPGSTHTTLFPDSTTSSGIVEAS 3746
Query: 444 TGKEKVTSGSTTTTRRSCSKT--------------VTKTVIGPDGHKEVTKEVVTSEDGS 489
T + ++GS TT S T T P T V S
Sbjct: 3747 T-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 3805
Query: 490 DCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTA--STGKTFPGFFSPMLGEFVSETESR 547
P + T G H +++ F ++ ++G T S G S T SR
Sbjct: 3806 RSPGSTPTTHFPASSTTSG----HSEKSTIFHSSPDASGTTPSSAHSTTSGRGES-TTSR 3860
Query: 548 GSESGIFTNTKESSSHHPGIAE----FPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
S T S+ PG++E F S +S + + S TS G+ + S+S
Sbjct: 3861 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 3917
Score = 45.4 bits (106), Expect = 2e-04
Identities = 100/396 (25%), Positives = 151/396 (38%), Gaps = 58/396 (14%)
Query: 263 RPGGNEITR--GGSTSYGTGSE-TESPRNPS------SAGSWNSGSSGPG-STGNRNPGS 312
RPG T G +T G E T S +P S GS + S GP +T + PGS
Sbjct: 670 RPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGS 729
Query: 313 SGT-----GGTATWKPGSSGP--GSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWNPGSS 365
+ T TA+ +S P ST S ++ S GST Q + + +W P S
Sbjct: 730 TETTLLPDNTTASGLLEASMPVHSSTRSPHTTLSPAGSTTRQGEST----TFHSW-PSSK 784
Query: 366 ERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEE-VSGNVSPGT 424
+ A T+ + V ST + GS P S + + + G EE + + SPG+
Sbjct: 785 DTRPAPPTTTSAFVEPST----TSHGS--PSSIPTTHISARSTTSGLVEESTTYHSSPGS 838
Query: 425 RREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVT 484
+ H + T+ G G+E TS S+TT S + + T ++ E +
Sbjct: 839 TQTMHFPESDTTSG-----RGEESTTSHSSTTHTISSAPSTTSALV------EEPTSYHS 887
Query: 485 SEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEFVSET 544
S + D T SG H D + T S +LGE +
Sbjct: 888 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTT-----SVLLGESTTSP 942
Query: 545 ESRGSESGIFTNTKESSSHHPGIAE----FPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
S GS + T S+ PG++E F S +S + + S+TS + + S+S
Sbjct: 943 ISSGS---METTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRS 999
Query: 601 YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSP 636
+ + D T R S H+SP
Sbjct: 1000 RPGSTHTTAFPDSTTTPGLSRHSTTS------HSSP 1029
Score = 45.4 bits (106), Expect = 2e-04
Identities = 91/366 (24%), Positives = 123/366 (33%), Gaps = 66/366 (18%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTG------------GTATW 321
ST+Y + + +P SA S G S +T + +PG++GT G T
Sbjct: 3164 STTYHS-RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTT 3222
Query: 322 KPGSSG-------PGSTGSWNSGSSGTGSTGNQNPGSP---------------RPGSTGT 359
P SSG PGST + +G S +T +P SP +T
Sbjct: 3223 SPISSGSTETTALPGSTTT--AGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSH 3280
Query: 360 WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSG 418
PGS+ + T+ VS + HS GS SPGS A P+ TF
Sbjct: 3281 SRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS--- 3337
Query: 419 NVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEV 478
PG+ T+ G E T T TT + S T G
Sbjct: 3338 --GPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTT-------RQGESTT 3388
Query: 479 TKEVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLG 538
+ S+D + P T S L H P +ST T S LG
Sbjct: 3389 FQSWPNSKDTTPAPPT----TTSAFVELSTTSHGSP--------SSTPTTHFSASSTTLG 3436
Query: 539 EFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQF----TSSTSYNRGDS 594
T S T + S G+ E + SS S Q S T+ RG+
Sbjct: 3437 RSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496
Query: 595 TFESKS 600
+ S S
Sbjct: 3497 STTSHS 3502
Score = 44.3 bits (103), Expect = 4e-04
Identities = 107/451 (23%), Positives = 162/451 (35%), Gaps = 102/451 (22%)
Query: 265 GGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSG-------PGSTGNRN--PGSSGT 315
G ++IT G + + G T S PSS+ + + S GST ++ S+ +
Sbjct: 160 GFSQIT-GSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVSVTFITGSTATKHFLDSSTNS 218
Query: 316 GGTATWKPGSSGPGSTGSWNSGSSGTGS-----------TGNQNPGSPRPGSTGT----- 359
G + SGPG+TG+ S S T + PGST T
Sbjct: 219 GHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSE 278
Query: 360 ------WNPGSSERGSAGHWTSESSVSGSTGQWHSESGSFR----PDS------------ 397
+P S +R + T+ S VS + HS G PDS
Sbjct: 279 KSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDSTTMPGVSQESTA 338
Query: 398 ----PGS-------GNARPNN--PDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELRT 444
PGS G P++ P+ TF SPG + T+ G E T
Sbjct: 339 SHSIPGSTDTTLSPGTTTPSSLGPESTTFHS-----SPGYTKTTRLPDNTTTSGLLEAST 393
Query: 445 GKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGIG 504
T TT S S T +G + +S+D S P GT S
Sbjct: 394 PVHSSTGSPHTTLSPSSSTT-------HEGEPTTFQSWPSSKDTSPAPS----GTTSAFV 442
Query: 505 TLDGFRHRHPDE--AAFFDTAST-----GKTFPGFFSPMLGEFVSETESRGSESGIFTNT 557
L H P F +ST ++ P SP + + +R + SG +
Sbjct: 443 KLSTTYHSSPSSTPTTHFSASSTTLGHSEESTPVHSSP-VATATTPPPARSATSG---HV 498
Query: 558 KESSSHH--PGIAE---FPSRGKSSSYSKQ---FTSSTSYNRGDSTFESKSYKMADEAGS 609
+ES+++H PG + FP +S +S++ F ST++ + + + + S
Sbjct: 499 EESTAYHRSPGSTQTMHFPESSTTSGHSEESATFHGSTTHTKSSTPSTTAALAHTSYHSS 558
Query: 610 EADHEGTH----STKRGHAKSRPVRGIHTSP 636
E TH ST G +S + H+SP
Sbjct: 559 LGSTETTHFRDSSTISG--RSEESKASHSSP 587
Score = 44.3 bits (103), Expect = 4e-04
Identities = 95/357 (26%), Positives = 129/357 (36%), Gaps = 56/357 (15%)
Query: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSG----PGSTGSWNSGSS 339
ES +P S+GS + ++ PGST PG S T P S P ST S SG S
Sbjct: 937 ESTTSPISSGSMET-TALPGST--TTPGLSERSTTFHSSPRSPATTLSPASTTS--SGVS 991
Query: 340 GTGSTGNQNPGSPR----PGSTGT-----------WNPGSSERGSAGHWTSESSVSGSTG 384
+T PGS P ST T +PGS++ T+ S S +
Sbjct: 992 EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 1051
Query: 385 QWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELR 443
HS SGS SPGS A + TF +PG+ TS G E
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHS-----NPGSTHTTLFPDSTTSSGIVEAS 1106
Query: 444 TGKEKVTSGSTTTTRRSCSKT--------------VTKTVIGPDGHKEVTKEVVTSEDGS 489
T + ++GS TT S T T P T V S
Sbjct: 1107 T-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 1165
Query: 490 DCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTA--STGKTFPGFFSPMLGEFVSETESR 547
P + T G H +++ F ++ ++G T S G S T SR
Sbjct: 1166 RSPGSTPTTHFPASSTTSG----HSEKSTIFHSSPDASGTTPSSAHSTTSGRGES-TTSR 1220
Query: 548 GSESGIFTNTKESSSHHPGIAE----FPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
S T S+ PG++E F S +S + + S TS G+ + S+S
Sbjct: 1221 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 1277
Score = 43.9 bits (102), Expect = 5e-04
Identities = 95/357 (26%), Positives = 129/357 (36%), Gaps = 56/357 (15%)
Query: 284 ESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWKPGSSG----PGSTGSWNSGSS 339
ES +P S+GS + ++ PGST PG S T P S P ST S SG S
Sbjct: 2020 ESTTSPISSGSMET-TALPGST--TTPGLSEKSTTFHSSPRSPATTLSPASTTS--SGVS 2074
Query: 340 GTGSTGNQNPGSPR----PGSTGT-----------WNPGSSERGSAGHWTSESSVSGSTG 384
+T + PGS P ST T +PGS++ T+ S S +
Sbjct: 2075 EESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 2134
Query: 385 QWHSESGSFRPD-SPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKELR 443
HS GS SPGS A + TF SPG+ TS G E
Sbjct: 2135 TSHSSPGSTDTALSPGSTTALSFGQESTTFHS-----SPGSTHTTLFPDSTTSSGIVEAS 2189
Query: 444 TGKEKVTSGSTTTTRRSCSKT--------------VTKTVIGPDGHKEVTKEVVTSEDGS 489
T + ++GS TT S T T P T V S
Sbjct: 2190 T-RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYH 2248
Query: 490 DCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTA--STGKTFPGFFSPMLGEFVSETESR 547
P + T G H +++ F ++ ++G T S G S T SR
Sbjct: 2249 RSPGSTPTTHFPASSTTSG----HSEKSTIFHSSPDASGTTPSSAHSTTSGRGES-TTSR 2303
Query: 548 GSESGIFTNTKESSSHHPGIAE----FPSRGKSSSYSKQFTSSTSYNRGDSTFESKS 600
S T S+ PG++E F S +S + + S TS G+ + S+S
Sbjct: 2304 ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRS 2360
Score = 41.6 bits (96), Expect = 0.002
Identities = 93/379 (24%), Positives = 128/379 (33%), Gaps = 48/379 (12%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
RP T S +G ES P S S +G +T + G +T
Sbjct: 2418 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-------LGEESTTF 2470
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWN-PGSSERGSAGHWTSESSVSG 381
P SSG T + S+ +G G P P ST T PGS S SE S +
Sbjct: 2471 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS----LSEKSTTF 2526
Query: 382 STGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVS-PGTRREYHTEKLVTSKGDK 440
T P SP + + G EE S + S PG+ T+ G
Sbjct: 2527 YTS----------PRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLS 2576
Query: 441 ELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLGTL 500
T + GST TT S T + GP ++E TS P + D
Sbjct: 2577 RHSTTSHS-SPGSTDTTLLPASTTTS----GP------SQESTTSHSS---PGSTDTALS 2622
Query: 501 SGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFF---SPMLGEFVSETESRGSESGIFTNT 557
G T F E+ F +S G T F + G + T S T
Sbjct: 2623 PGSTTALSF----GQESTTFH-SSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTL 2677
Query: 558 KESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKSYKMADEAGSEADHEGTH 617
+SS PG+ + ++ S T S ES +Y + + H
Sbjct: 2678 SPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRS-PGSTPTTHFPAS 2736
Query: 618 STKRGHAKSRPVRGIHTSP 636
ST GH++ + H+SP
Sbjct: 2737 STTSGHSEKSTI--FHSSP 2753
Score = 41.6 bits (96), Expect = 0.002
Identities = 87/367 (23%), Positives = 132/367 (35%), Gaps = 56/367 (15%)
Query: 274 STSYGTGSETESPRNPSSAGSWNSGS------SGPGSTGNR----NPGSSGTGGTATWKP 323
+TS+ + T++ +P S + + G S PGST + SSG +T
Sbjct: 2608 TTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVH 2667
Query: 324 GSSGPGST-----GSWNSGSSGTGSTGNQNPGS----PRPGSTGTW--NPGSSERGSAGH 372
S+G T S + G G +T +P S P P ST T ++ S G
Sbjct: 2668 SSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGS 2727
Query: 373 WTSESSVSGSTGQWHSESGSF---RPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYH 429
+ + ST HSE + PD+ G+ + ++ G E + +SPG+
Sbjct: 2728 TPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITT 2787
Query: 430 TEKLVTSKGDKELRT-------------GKEKVTS---GSTTTTRR----SCSKTVTKTV 469
T+ G E T +TS G +TT R S TV+
Sbjct: 2788 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPAS 2847
Query: 470 IGPDGHKEVTKEVVTSEDGSDCPEAMDLGTLSGI-GTLDGFRHRHP--DEAAFF--DTAS 524
G E + V +S GS T + + G H P F D+ +
Sbjct: 2848 TTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTT 2907
Query: 525 TGKT-----FPGFFSPMLGEFVSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSY 579
+G T FPG SP + ++ G + T SSS G P+R +S
Sbjct: 2908 SGLTEESTAFPG--SPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGL 2965
Query: 580 SKQFTSS 586
+ T S
Sbjct: 2966 VGESTPS 2972
Score = 37.0 bits (84), Expect = 0.056
Identities = 53/211 (25%), Positives = 76/211 (36%), Gaps = 24/211 (11%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
RP T S +G ES P S S +G +T + G +T
Sbjct: 1335 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-------LGEESTTF 1387
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWN-PGS------SERGSAGHWTS 375
P SSG T + S+ +G G P P ST T PGS SE+ + + +
Sbjct: 1388 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 1447
Query: 376 ES-----SVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
S S + +T SE S PGS + PD T ++S + + T
Sbjct: 1448 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA-FPDSTTTSDLSQEPTTSHSSQGST 1506
Query: 431 EKLVTSKGDKELRTGKEKVT----SGSTTTT 457
E ++ G++ T G T TT
Sbjct: 1507 EATLSPGSTTASSLGQQSTTFHSSPGDTETT 1537
Score = 35.4 bits (80), Expect = 0.16
Identities = 53/211 (25%), Positives = 75/211 (35%), Gaps = 24/211 (11%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
RP T S +G ES P S S +G +T + G +T
Sbjct: 2892 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-------LGEESTTF 2944
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWN-PGS------SERGSAGHWTS 375
P SSG T + S+ +G G P P ST T PGS SE+ + + +
Sbjct: 2945 PSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 3004
Query: 376 ES-----SVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
S S + +T SE S PGS + PD T +S + + T
Sbjct: 3005 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA-FPDSTTTSGLSQEPTASHSSQGST 3063
Query: 431 EKLVTSKGDKELRTGKEKVT----SGSTTTT 457
E ++ G++ T G T TT
Sbjct: 3064 EATLSPGSTTASSLGQQSTTFHSSPGDTETT 3094
Score = 35.4 bits (80), Expect = 0.16
Identities = 53/211 (25%), Positives = 75/211 (35%), Gaps = 24/211 (11%)
Query: 263 RPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSSGPGSTGNRNPGSSGTGGTATWK 322
RP T S +G ES P S S +G +T + G +T
Sbjct: 3975 RPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTAD-------LGEESTTF 4027
Query: 323 PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTWN-PGS------SERGSAGHWTS 375
P SSG T + S+ +G G P P ST T PGS SE+ + + +
Sbjct: 4028 PSSSGSTGTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSP 4087
Query: 376 ES-----SVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNVSPGTRREYHT 430
S S + +T SE S PGS + PD T +S + + T
Sbjct: 4088 RSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTA-FPDSTTTSGLSQEPTTSHSSQGST 4146
Query: 431 EKLVTSKGDKELRTGKEKVT----SGSTTTT 457
E ++ G++ T G T TT
Sbjct: 4147 EATLSPGSTTASSLGQQSTTFHSSPGDTETT 4177
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.379
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,239,722
Number of Sequences: 37866
Number of extensions: 1651538
Number of successful extensions: 13376
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 157
Number of HSP's successfully gapped in prelim test: 677
Number of HSP's that attempted gapping in prelim test: 7541
Number of HSP's gapped (non-prelim): 3139
length of query: 644
length of database: 18,247,518
effective HSP length: 109
effective length of query: 535
effective length of database: 14,120,124
effective search space: 7554266340
effective search space used: 7554266340
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.