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Search of human proteins with 10863961
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
(538 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 1067 0.0
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 1043 0.0
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 1043 0.0
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 478 e-135
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 478 e-135
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 478 e-135
gi|15718767 TRAAK [Homo sapiens] 315 7e-86
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 199 5e-51
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 199 5e-51
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 179 6e-45
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 179 7e-45
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 178 1e-44
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 153 3e-37
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 151 1e-36
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 130 2e-30
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 129 7e-30
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 124 2e-28
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 124 2e-28
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 122 6e-28
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 112 1e-24
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 110 2e-24
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 110 2e-24
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 110 2e-24
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 108 2e-23
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 104 2e-22
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 76 9e-14
gi|4504831 potassium voltage-gated channel, subfamily H, member ... 42 0.001
gi|27437001 potassium voltage-gated channel, subfamily H, member... 42 0.001
gi|27436981 potassium voltage-gated channel, Shal-related subfam... 42 0.001
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 41 0.002
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 1067 bits (2760), Expect = 0.0
Identities = 538/538 (100%), Positives = 538/538 (100%)
Query: 1 MFFLYTDFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQ 60
MFFLYTDFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQ
Sbjct: 1 MFFLYTDFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQ 60
Query: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVS 120
GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVS
Sbjct: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVS 120
Query: 121 PQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGG 180
PQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGG
Sbjct: 121 PQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGG 180
Query: 181 KIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFI 240
KIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFI
Sbjct: 181 KIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFI 240
Query: 241 LAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLV 300
LAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLV
Sbjct: 241 LAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLV 300
Query: 301 WFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSV 360
WFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSV
Sbjct: 301 WFWILVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSV 360
Query: 361 EIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRP 420
EIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRP
Sbjct: 361 EIHDKLQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRP 420
Query: 421 NNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYS 480
NNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYS
Sbjct: 421 NNLRLKGPEQLNKHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYS 480
Query: 481 LDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 538
LDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN
Sbjct: 481 LDEEKKEEETEKMCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 538
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 1043 bits (2697), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 13 VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV 72
VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV
Sbjct: 18 VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV 77
Query: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 132
VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 137
Query: 133 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI 192
DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI
Sbjct: 138 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI 197
Query: 193 PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA 252
PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA
Sbjct: 198 PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA 257
Query: 253 VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA 312
VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA
Sbjct: 258 VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA 317
Query: 313 AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI 372
AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI
Sbjct: 318 AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI 377
Query: 373 RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN 432
RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN
Sbjct: 378 RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN 437
Query: 433 KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK 492
KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK
Sbjct: 438 KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK 497
Query: 493 MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 538
MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN
Sbjct: 498 MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 543
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 1043 bits (2697), Expect = 0.0
Identities = 526/526 (100%), Positives = 526/526 (100%)
Query: 13 VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV 72
VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV
Sbjct: 18 VAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVARMEGTSQGGLQTVMKWKTV 77
Query: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 132
VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL
Sbjct: 78 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 137
Query: 133 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI 192
DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI
Sbjct: 138 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGI 197
Query: 193 PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA 252
PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA
Sbjct: 198 PLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPA 257
Query: 253 VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA 312
VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA
Sbjct: 258 VIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFA 317
Query: 313 AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI 372
AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI
Sbjct: 318 AVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATI 377
Query: 373 RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN 432
RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN
Sbjct: 378 RSMERRRLGLDQRAHSLDMLSPEKRSVFAALDTGRFKASSQESINNRPNNLRLKGPEQLN 437
Query: 433 KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK 492
KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK
Sbjct: 438 KHGQGASEDNIINKFGSTSRLTKRKNKDLKKTLPEDVQKIYKTFRNYSLDEEKKEEETEK 497
Query: 493 MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 538
MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN
Sbjct: 498 MCNSDNSSTAMLTDCIQQHAELENGMIPTDTKDREPENNSLLEDRN 543
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 478 bits (1231), Expect = e-135
Identities = 247/394 (62%), Positives = 305/394 (77%), Gaps = 23/394 (5%)
Query: 7 DFFLSLVAVPAAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQT 65
DF+L AA + PKSA A PRLS S++ TV+A R+E +
Sbjct: 9 DFYL------AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---IN 51
Query: 66 VMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELE 125
VMKWKTV IF+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+
Sbjct: 52 VMKWKTVSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELD 111
Query: 126 TLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCI 185
LIQ + A NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI
Sbjct: 112 ELIQQIVAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCI 171
Query: 186 LYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCI 245
+YA+ GIPLFGFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC+
Sbjct: 172 IYALLGIPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCV 231
Query: 246 VFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWIL 305
+FV +PA+IFK+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWIL
Sbjct: 232 LFVALPAIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWIL 290
Query: 306 VGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDK 365
VGLAYFAAVLSMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK
Sbjct: 291 VGLAYFAAVLSMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDK 350
Query: 366 LQRAATIRSMERRRLGLDQRAHSLDMLSPEKRSV 399
QRA +I +R+L + + L+P +R++
Sbjct: 351 FQRATSI----KRKLSAELAGNHNQELTPCRRTL 380
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 478 bits (1229), Expect = e-135
Identities = 244/384 (63%), Positives = 301/384 (78%), Gaps = 17/384 (4%)
Query: 17 AAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQTVMKWKTVVAI 75
AA + PKSA A PRLS S++ TV+A R+E + VMKWKTV I
Sbjct: 2 AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---INVMKWKTVSTI 50
Query: 76 FVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDAD 135
F+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+ LIQ + A
Sbjct: 51 FLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAI 110
Query: 136 NAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLF 195
NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI+YA+ GIPLF
Sbjct: 111 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 170
Query: 196 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIF 255
GFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC++FV +PA+IF
Sbjct: 171 GFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIF 230
Query: 256 KYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 315
K+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWILVGLAYFAAVL
Sbjct: 231 KHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVL 289
Query: 316 SMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSM 375
SMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK QRA +I
Sbjct: 290 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSI--- 346
Query: 376 ERRRLGLDQRAHSLDMLSPEKRSV 399
+R+L + + L+P +R++
Sbjct: 347 -KRKLSAELAGNHNQELTPCRRTL 369
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 478 bits (1229), Expect = e-135
Identities = 244/384 (63%), Positives = 301/384 (78%), Gaps = 17/384 (4%)
Query: 17 AAAPVCQPKSATNGQPPAPAPTPTPRLSISSRATVVA-RMEGTSQGGLQTVMKWKTVVAI 75
AA + PKSA A PRLS S++ TV+A R+E + VMKWKTV I
Sbjct: 17 AAPDLLDPKSA--------AQNSKPRLSFSTKPTVLASRVESDTT---INVMKWKTVSTI 65
Query: 76 FVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDAD 135
F+VVV+YL+ G VF+ALEQP E SQ+ TI ++K F+ H CV+ EL+ LIQ + A
Sbjct: 66 FLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAAI 125
Query: 136 NAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLF 195
NAG+ P+GN+SN SHWDLGS+FFFAGTVITTIG+GNI+P TEGGKIFCI+YA+ GIPLF
Sbjct: 126 NAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPLF 185
Query: 196 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIF 255
GFLLAG+GDQLGTIFGK IA+VE F K VSQTKIR+ISTI+FIL GC++FV +PA+IF
Sbjct: 186 GFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALPAIIF 245
Query: 256 KYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 315
K+IEGW+AL++IYFVV+TLTT+GFGD+VAGG + I Y ++YKP+VWFWILVGLAYFAAVL
Sbjct: 246 KHIEGWSALDAIYFVVITLTTIGFGDYVAGG-SDIEYLDFYKPVVWFWILVGLAYFAAVL 304
Query: 316 SMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRRRLSVEIHDKLQRAATIRSM 375
SMIGDWLRV+SKKTKEEVGE +AHAAEW ANVTAEF+ETRRRLSVEI+DK QRA +I
Sbjct: 305 SMIGDWLRVISKKTKEEVGEFRAHAAEWTANVTAEFKETRRRLSVEIYDKFQRATSI--- 361
Query: 376 ERRRLGLDQRAHSLDMLSPEKRSV 399
+R+L + + L+P +R++
Sbjct: 362 -KRKLSAELAGNHNQELTPCRRTL 384
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 315 bits (807), Expect = 7e-86
Identities = 157/292 (53%), Positives = 210/292 (71%), Gaps = 5/292 (1%)
Query: 67 MKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELET 126
M+ T++A+ +V++YLV+G LVFRALEQP E + + + +FLR H CVS QEL
Sbjct: 1 MRSTTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGL 60
Query: 127 LIQHALDADNAGVSPIGNSSNNSSH--WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFC 184
LI+ DA G P NS++NSSH WDLGSAFFF+GT+ITTIGYGN+A T+ G++FC
Sbjct: 61 LIKEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFC 120
Query: 185 ILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGC 244
I YA+ GIPLFG LLAG+GD+LG+ I +E +F K V +RV+S +LF+L GC
Sbjct: 121 IFYALVGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPPELVRVLSAMLFLLIGC 180
Query: 245 IVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWI 304
++FV P +F Y+E W+ LE+IYFV+VTLTTVGFGD+VAG + + Y+PLVWFWI
Sbjct: 181 LLFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADPRQD-SPAYQPLVWFWI 239
Query: 305 LVGLAYFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAAEWKANVTAEFRETRR 356
L+GLAYFA+VL+ IG+WLRV+S++T+ E+G + A AA W VTA R T+R
Sbjct: 240 LLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTA--RVTQR 289
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 199 bits (506), Expect = 5e-51
Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)
Query: 72 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 311
++F ++EGW+ E YF +TL+T+GFGD+V G + +Y Y+ L WIL+GLA+
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
Query: 312 AAVLSM 317
A +L +
Sbjct: 248 ALILPL 253
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 199 bits (506), Expect = 5e-51
Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)
Query: 72 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 311
++F ++EGW+ E YF +TL+T+GFGD+V G + +Y Y+ L WIL+GLA+
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
Query: 312 AAVLSM 317
A +L +
Sbjct: 248 ALILPL 253
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 179 bits (454), Expect = 6e-45
Identities = 89/218 (40%), Positives = 137/218 (62%), Gaps = 6/218 (2%)
Query: 72 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAG 289
++F ++EGW+ E YF +TL+T+GFGD+V G G
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGLRQG 225
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 179 bits (453), Expect = 7e-45
Identities = 88/214 (41%), Positives = 136/214 (63%), Gaps = 6/214 (2%)
Query: 72 VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131
V+ + + V YL+ G +F+ LE+ E+ ++ LEK FL ++ C+ +E +Q
Sbjct: 14 VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
Query: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
++A GV+P GNS+N S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 74 MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251
IPL L + LGT +A +E+ + + SQ ++V+ LF+ G +V + P
Sbjct: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
Query: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAG 285
++F ++EGW+ E YF +TL+T+GFGD+V G
Sbjct: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 178 bits (452), Expect = 1e-44
Identities = 89/243 (36%), Positives = 138/243 (56%), Gaps = 10/243 (4%)
Query: 79 VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAG 138
++ YL G +F LE+P K +K L++ C+ + L+ +++ DA G
Sbjct: 12 IIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVSDAAGQG 71
Query: 139 VSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFL 198
V+ GN + N+ +W +A FA TVITTIGYGN+AP T G++FC+ Y +FG+PL
Sbjct: 72 VAITGNQTFNNWNWP--NAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVPLCLTW 129
Query: 199 LAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYI 258
++ LG FG R+ + K+ VS K ++ T++FI+ G +V + IP +F
Sbjct: 130 ISA----LGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMVT 185
Query: 259 EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVLSMI 318
EGW +E +Y+ +T++T+GFGDFVAG N NY Y+ V WI +GLA+ LS+
Sbjct: 186 EGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAW----LSLF 241
Query: 319 GDW 321
+W
Sbjct: 242 VNW 244
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 153 bits (387), Expect = 3e-37
Identities = 81/248 (32%), Positives = 137/248 (55%), Gaps = 5/248 (2%)
Query: 71 TVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQH 130
+ V + + + YL G VF LE + +K E L++ C+ L++LI+
Sbjct: 21 STVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRD 80
Query: 131 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 190
+ A G S + N+++ W+L +FFF+ + ITTIGYGN++P+T ++FCI +A+
Sbjct: 81 VVQAYKNGASLLSNTTS-MGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139
Query: 191 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 250
GIPL +L ++LG + + + K R ++ +L+G ++F+ +
Sbjct: 140 GIPLNLVVL----NRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLL 195
Query: 251 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAY 310
P ++F ++EGW+ E YF +TL+TVGFGD+V G N Y WYK +V WIL G+A+
Sbjct: 196 PPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKNMVSLWILFGMAW 255
Query: 311 FAAVLSMI 318
A ++ +I
Sbjct: 256 LALIIKLI 263
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 151 bits (382), Expect = 1e-36
Identities = 84/239 (35%), Positives = 132/239 (55%), Gaps = 8/239 (3%)
Query: 80 VVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGV 139
++YLV G +VF ++E P+E + + K FL +H C+S Q+LE + L+A N GV
Sbjct: 31 LLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEASNYGV 90
Query: 140 SPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLL 199
S + N+S N + WD SA FFA TV++T GYG+ P ++GGK FCI+Y++ GIP L
Sbjct: 91 SVLSNASGNWN-WDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFTLLFL 149
Query: 200 AGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--FILAGCIVFVTIPAVIFKY 257
+ ++ + + + S+ + ++ +L F+ C F IPA +F
Sbjct: 150 TAVVQRITVHVTRRPVLYFHI--RWGFSKQVVAIVHAVLLGFVTVSCFFF--IPAAVFSV 205
Query: 258 IE-GWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAVL 315
+E W LES YF ++L+T+G GD+V G +RE YK + ++L+GL VL
Sbjct: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 130 bits (328), Expect = 2e-30
Identities = 85/264 (32%), Positives = 137/264 (51%), Gaps = 22/264 (8%)
Query: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP---QELETLIQ 129
+A+ V YL+ G VF ALE E ++ + L + E LR +S +ELE ++
Sbjct: 9 LALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQE-LRARYNLSQGGYEELERVVL 67
Query: 130 HALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAI 189
L AGV W +F+FA TVITTIGYG+ APST+GGK+FC+ YA+
Sbjct: 68 R-LKPHKAGVQ-----------WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYAL 115
Query: 190 FGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVT 249
GIPL + +G+++ T+ + R +K ++ + + + +L CI +
Sbjct: 116 LGIPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRAD---VSMANMVLIGFFSCISTLC 172
Query: 250 IPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGL 308
I A F + E WT ++ Y+ +TLTT+GFGD+VA + + + Y + +IL GL
Sbjct: 173 IGAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGL 232
Query: 309 AYFAAVLSMIGDWLRVLSKKTKEE 332
A L+++ LR ++ ++E
Sbjct: 233 TVIGAFLNLV--VLRFMTMNAEDE 254
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 129 bits (324), Expect = 7e-30
Identities = 80/241 (33%), Positives = 122/241 (50%), Gaps = 11/241 (4%)
Query: 82 YLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNAGVSP 141
YLV G L+ LE P E+ + + +A+ L+ CV+ L+ ++ L A G
Sbjct: 17 YLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFVERVLAAGRLGRVV 76
Query: 142 IGNSSNNSSH----WDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGF 197
+ N+S +++ WD SA FFA T+ITT+GYG P T+ GK F I +A+ G+P
Sbjct: 77 LANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTML 136
Query: 198 LLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFV--TIPAVIF 255
LL +L + + V + + R L L G +V V +PAVIF
Sbjct: 137 LLTASAQRLSLL----LTHVPLSWLSMRWGWDPRRAACWHLVALLGVVVTVCFLVPAVIF 192
Query: 256 KYI-EGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYFAAV 314
++ E W+ L++ YF ++L+T+G GD+V G G YR YK LV ++ +GL V
Sbjct: 193 AHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLVTVYLFLGLVAMVLV 252
Query: 315 L 315
L
Sbjct: 253 L 253
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 124 bits (312), Expect = 2e-28
Identities = 85/301 (28%), Positives = 145/301 (48%), Gaps = 26/301 (8%)
Query: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSP--QELETLIQH 130
+++ V YL+ G VF ALE E ++ + E+ + S ++LE +I
Sbjct: 9 LSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVILQ 68
Query: 131 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 190
+ + AGV W +F+FA TVITTIGYG+ AP T+ GK FC+ YA+
Sbjct: 69 S-EPHRAGVQ-----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116
Query: 191 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 250
GIPL + +G+++ T + R++K + + +++ F C+ + I
Sbjct: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFF---SCMGTLCI 173
Query: 251 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAG-INYREWYKPLVWFWILVGLA 309
A F E W+ + Y+ +TLTT+GFGD+VA G + + Y + +ILVGL
Sbjct: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233
Query: 310 YFAAVLSMIGDWLRVLSKKTKEEVGEIKAHAA------EWKANVTAEFRETRRRLSVEIH 363
A L+++ LR L+ +++E + + A+ ++ E R +R R ++
Sbjct: 234 VIGAFLNLV--VLRFLTMNSEDERRDAEERASLAGNRNSMVIHIPEEPRPSRPRYKADVP 291
Query: 364 D 364
D
Sbjct: 292 D 292
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 124 bits (311), Expect = 2e-28
Identities = 67/213 (31%), Positives = 117/213 (54%), Gaps = 5/213 (2%)
Query: 71 TVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQH 130
+ V + + + YL G VF LE + +K E L++ C+ L++LI+
Sbjct: 21 STVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRD 80
Query: 131 ALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIF 190
+ A G S + N+++ W+L +FFF+ + ITTIGYGN++P+T ++FCI +A+
Sbjct: 81 VVQAYKNGASLLSNTTS-MGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALV 139
Query: 191 GIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTI 250
GIPL +L ++LG + + + K R ++ +L+G ++F+ +
Sbjct: 140 GIPLNLVVL----NRLGHLMQQGVNHWASRLGGTWQDPDKARWLAGSGALLSGLLLFLLL 195
Query: 251 PAVIFKYIEGWTALESIYFVVVTLTTVGFGDFV 283
P ++F ++EGW+ E YF +TL+TVGFGD+V
Sbjct: 196 PPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 122 bits (307), Expect = 6e-28
Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 20/248 (8%)
Query: 75 IFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDA 134
+ + + YL+ G VF ALE ES ++ + ++K LR S ++ L + AL A
Sbjct: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLL-VQKRGALRRKFGFSAEDYRELERLALQA 69
Query: 135 DNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 194
+ W +F+FA TVITTIGYG+ AP T+ GK+FC+ YA+ GIPL
Sbjct: 70 E---------PHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
Query: 195 FGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAG---CIVFVTIP 251
+G++L + + + K + +ST ++AG C + +
Sbjct: 121 TLVTFQSLGERLNAVVRRLL------LAAKCCLGLRWTCVSTENLVVAGLLACAATLALG 174
Query: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAY 310
AV F + EGWT + Y+ +TLTT+GFGDFVA + + Y + +IL+GL
Sbjct: 175 AVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTV 234
Query: 311 FAAVLSMI 318
A L+++
Sbjct: 235 IGAFLNLV 242
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 112 bits (279), Expect = 1e-24
Identities = 88/289 (30%), Positives = 141/289 (48%), Gaps = 20/289 (6%)
Query: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 119
GGL+ W + V ++ L G +VF+ALE P + + E A F +H C+
Sbjct: 2 GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
Query: 120 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 179
P LE L+ AL GVS +GNSS + WDL SA FA +++TT GYG++AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
Query: 180 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 239
GK FC++YA G+P L+A + L + + A V + Q+S + ++ +
Sbjct: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
Query: 240 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAGGNAGIN---YREW 295
L FV +PA++ ++G + L ++YF +L+T+G D + G ++ Y
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLG 234
Query: 296 YKPLVWFWILVGLAYFAAV--------LSMIGDWLRVLSKKTKEEVGEI 336
L+ + +L LA AV + +G + R T E+ G I
Sbjct: 235 QLALLGYLLLGLLAMLLAVETFSELPQVRAMGKFFRPSGPVTAEDQGGI 283
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 110 bits (276), Expect = 2e-24
Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)
Query: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 119
GGL+ W + V ++ L G +VF+ALE P + + E A F +H C+
Sbjct: 2 GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
Query: 120 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 179
P LE L+ AL GVS +GNSS + WDL SA FA +++TT GYG++AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
Query: 180 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 239
GK FC++YA G+P L+A + L + + A V + Q+S + ++ +
Sbjct: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
Query: 240 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 285
L FV +PA++ ++G + L ++YF +L+T+G D + G
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 110 bits (276), Expect = 2e-24
Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)
Query: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 119
GGL+ W + V ++ L G +VF+ALE P + + E A F +H C+
Sbjct: 2 GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
Query: 120 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 179
P LE L+ AL GVS +GNSS + WDL SA FA +++TT GYG++AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
Query: 180 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 239
GK FC++YA G+P L+A + L + + A V + Q+S + ++ +
Sbjct: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
Query: 240 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 285
L FV +PA++ ++G + L ++YF +L+T+G D + G
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 110 bits (276), Expect = 2e-24
Identities = 75/227 (33%), Positives = 119/227 (52%), Gaps = 9/227 (3%)
Query: 61 GGLQTVMKWKTVVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDH-VCV 119
GGL+ W + V ++ L G +VF+ALE P + + E A F +H C+
Sbjct: 2 GGLRP---WSRYGLLVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACL 58
Query: 120 SPQELETLIQHALDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEG 179
P LE L+ AL GVS +GNSS + WDL SA FA +++TT GYG++AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRT-WDLPSALLFAASILTTTGYGHMAPLSPG 117
Query: 180 GKIFCILYAIFGIPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILF 239
GK FC++YA G+P L+A + L + + A V + Q+S + ++ +
Sbjct: 118 GKAFCMVYAALGLPASLALVATLRHCLLPVLSRPRAWVAVHW---QLSPARAALLQAVAL 174
Query: 240 ILAGCIVFVTIPAVIFKYIEG-WTALESIYFVVVTLTTVGFGDFVAG 285
L FV +PA++ ++G + L ++YF +L+T+G D + G
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPG 221
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 108 bits (269), Expect = 2e-23
Identities = 80/267 (29%), Positives = 124/267 (46%), Gaps = 39/267 (14%)
Query: 78 VVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDADNA 137
++V+YL+ G VF ALE E K A F R H +S EL ++H +A A
Sbjct: 26 LIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRHYEEATRA 84
Query: 138 GVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG----IP 193
G+ N WD AF+F GTV++TIG+G P+T GGKIF I Y + G I
Sbjct: 85 GI----RVDNVRPRWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
Query: 194 LFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQT----------------------KI 231
F L ++L TI IA + K ++Q+ + K
Sbjct: 141 FFNLFL----ERLITI----IAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKP 192
Query: 232 RVISTILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGIN 291
V +L + I+ + ++ IEGW+ +S+YF V +T+GFGD V+ NA
Sbjct: 193 SVYYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYE 252
Query: 292 YREWYKPLVWFWILVGLAYFAAVLSMI 318
+ Y+ + +IL+G+ ++ ++I
Sbjct: 253 SQGLYRFANFVFILMGVCCIYSLFNVI 279
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 104 bits (259), Expect = 2e-22
Identities = 71/264 (26%), Positives = 120/264 (45%), Gaps = 23/264 (8%)
Query: 73 VAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHAL 132
V + ++ +YLV G VF ALE P E+ + F H P EL ++H
Sbjct: 40 VLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNFSAAHGVAEP-ELRAFLRHYE 98
Query: 133 DADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG- 191
A AGV + WD AF+F GTV++TIG+G P+T GGK F I Y +FG
Sbjct: 99 AALAAGV----RADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGC 154
Query: 192 --------------IPLFGFLLAGIGD---QLGTIFGKSIARVEKVFRKKQVSQTKIRVI 234
I L F++ + + + + R + ++ K V
Sbjct: 155 AGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVY 214
Query: 235 STILFILAGCIVFVTIPAVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYRE 294
+L + ++ + ++ +EGW ++S+YF VT +T+GFGD V+ +A +
Sbjct: 215 HVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHAAYRNQG 274
Query: 295 WYKPLVWFWILVGLAYFAAVLSMI 318
Y+ + +IL+G+ ++ ++I
Sbjct: 275 LYRLGNFLFILLGVCCIYSLFNVI 298
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 75.9 bits (185), Expect = 9e-14
Identities = 51/146 (34%), Positives = 72/146 (49%), Gaps = 12/146 (8%)
Query: 79 VVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLR--DHVCVSPQELETLIQHA---LD 133
+V Y + G +VF A+E + +A + EF + + +C ET+++ L
Sbjct: 30 LVTYALVGAVVFSAIEDG-----QVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDLQ 84
Query: 134 ADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIP 193
V P N ++HW S+ FF TV +T+GYG I P T GK C+LYA+FGIP
Sbjct: 85 GHLQKVKP--QWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIP 142
Query: 194 LFGFLLAGIGDQLGTIFGKSIARVEK 219
L +L GD L TI S R K
Sbjct: 143 LMFLVLTDTGDILATILSTSYNRFRK 168
Score = 34.3 bits (77), Expect = 0.30
Identities = 24/79 (30%), Positives = 39/79 (49%), Gaps = 7/79 (8%)
Query: 206 LGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIPAVIFKYIEGWTALE 265
LG + I+ +++V ++ + + +I+ I+F C A I + E E
Sbjct: 258 LGRLSYSIISNLDEVGQQVERLDIPLPIIALIVFAYISCA------AAILPFWETQLDFE 311
Query: 266 S-IYFVVVTLTTVGFGDFV 283
+ YF VTLTT+GFGD V
Sbjct: 312 NAFYFCFVTLTTIGFGDTV 330
>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
isoform 2 [Homo sapiens]
Length = 962
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 140 SPIGNSSNNSSHWDLG--------SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
+P + + S W+ G S+ +F T +T++G+GNIAPST+ KIF + + G
Sbjct: 401 TPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIG 460
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEK 219
L A I + TIF + A +
Sbjct: 461 ----SLLYATIFGNVTTIFQQMYANTNR 484
>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
isoform 1 [Homo sapiens]
Length = 989
Score = 42.4 bits (98), Expect = 0.001
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 12/88 (13%)
Query: 140 SPIGNSSNNSSHWDLG--------SAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191
+P + + S W+ G S+ +F T +T++G+GNIAPST+ KIF + + G
Sbjct: 428 TPYQFNGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIG 487
Query: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEK 219
L A I + TIF + A +
Sbjct: 488 ----SLLYATIFGNVTTIFQQMYANTNR 511
>gi|27436981 potassium voltage-gated channel, Shal-related
subfamily, member 1 [Homo sapiens]
Length = 647
Score = 42.0 bits (97), Expect = 0.001
Identities = 23/88 (26%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Query: 146 SNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQ 205
+N ++ + +AF++ +TT+GYG++ PST GKIF + ++ G+ + + I
Sbjct: 351 TNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAGKIFGSICSLSGVLVIALPVPVIVSN 410
Query: 206 LGTIFGKSIARVEKVFRKKQVSQTKIRV 233
I+ ++ R +K +++V +IR+
Sbjct: 411 FSRIYHQN-QRADKRRAQQKVRLARIRL 437
Score = 32.7 bits (73), Expect = 0.86
Identities = 28/109 (25%), Positives = 51/109 (46%), Gaps = 16/109 (14%)
Query: 196 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--------FILAGCIVF 247
G L+ D G + RV ++F+ + SQ +R++ L F+L +
Sbjct: 278 GLLVPKNDDVSGAFVTLRVFRVFRIFKFSRHSQG-LRILGYTLKSCASELGFLLFSLTMA 336
Query: 248 VTIPAVIFKYIE------GWTALESIY-FVVVTLTTVGFGDFVAGGNAG 289
+ I A + Y E +T++ + + + +VT+TT+G+GD V AG
Sbjct: 337 IIIFATVMFYAEKGTNKTNFTSIPAAFWYTIVTMTTLGYGDMVPSTIAG 385
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 41.2 bits (95), Expect = 0.002
Identities = 24/91 (26%), Positives = 47/91 (51%), Gaps = 1/91 (1%)
Query: 146 SNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPLFGFLLAGIGDQ 205
S+ S + ++F++ +TT+GYG++ P T GKIF + ++ G+ + + I
Sbjct: 346 SSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVLVIALPVPVIVSN 405
Query: 206 LGTIFGKSIARVEKVFRKKQVSQTKIRVIST 236
I+ ++ R +K +K+ +IRV T
Sbjct: 406 FSRIYHQN-QRADKRRAQKKARLARIRVAKT 435
Score = 33.1 bits (74), Expect = 0.66
Identities = 27/109 (24%), Positives = 49/109 (44%), Gaps = 16/109 (14%)
Query: 196 GFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTIL--------FILAGCIVF 247
G ++ D G + RV ++F+ + SQ +R++ L F+L +
Sbjct: 273 GLVMTNNEDVSGAFVTLRVFRVFRIFKFSRHSQG-LRILGYTLKSCASELGFLLFSLTMA 331
Query: 248 VTIPAVIFKYIEGWTALE-------SIYFVVVTLTTVGFGDFVAGGNAG 289
+ I A + Y E ++ S ++ +VT+TT+G+GD V AG
Sbjct: 332 IIIFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAG 380
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.393
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,375,815
Number of Sequences: 37866
Number of extensions: 878334
Number of successful extensions: 6920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 122
Number of HSP's successfully gapped in prelim test: 70
Number of HSP's that attempted gapping in prelim test: 6471
Number of HSP's gapped (non-prelim): 431
length of query: 538
length of database: 18,247,518
effective HSP length: 107
effective length of query: 431
effective length of database: 14,195,856
effective search space: 6118413936
effective search space used: 6118413936
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.