Guide to the Human Genome
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Search of human proteins with 239748777

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
         (350 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]           725   0.0  
gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]           223   2e-58
gi|239754245 PREDICTED: hypothetical protein [Homo sapiens]           185   5e-47
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     62   6e-10
gi|158854042 hypothetical protein LOC222183 [Homo sapiens]             62   8e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    60   2e-09
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    60   4e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        60   4e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    59   6e-09
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     59   6e-09
gi|112421108 capicua homolog [Homo sapiens]                            59   8e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    57   2e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    57   2e-08
gi|91208420 bassoon protein [Homo sapiens]                             57   2e-08
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         57   2e-08
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]            57   2e-08
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]            57   2e-08
gi|163965366 nascent polypeptide-associated complex alpha subuni...    57   3e-08
gi|238908524 hypothetical protein LOC389333 [Homo sapiens]             56   5e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    55   7e-08
gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]     55   1e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is...    54   2e-07
gi|95147559 ankyrin repeat domain 43 [Homo sapiens]                    54   2e-07
gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]            54   2e-07
gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo ...    54   2e-07
gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo ...    54   2e-07
gi|14149696 SEC31 homolog B [Homo sapiens]                             54   2e-07
gi|18959210 WIRE protein [Homo sapiens]                                54   2e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens]                       53   4e-07
gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]         53   4e-07

>gi|239748777 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 350

 Score =  725 bits (1872), Expect = 0.0
 Identities = 350/350 (100%), Positives = 350/350 (100%)

Query: 1   MCREKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPP 60
           MCREKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPP
Sbjct: 1   MCREKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPP 60

Query: 61  SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW 120
           SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW
Sbjct: 61  SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW 120

Query: 121 RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG 180
           RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG
Sbjct: 121 RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG 180

Query: 181 EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240
           EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP
Sbjct: 181 EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240

Query: 241 CATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSG 300
           CATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSG
Sbjct: 241 CATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSG 300

Query: 301 TQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 350
           TQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS
Sbjct: 301 TQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 350


>gi|169169586 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 251

 Score =  223 bits (568), Expect = 2e-58
 Identities = 133/235 (56%), Positives = 139/235 (59%), Gaps = 17/235 (7%)

Query: 133 RSRHPHT-RYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGE---AGPPRGD 188
           + RH H+ R P     ATP R P       +  PG   SP PA    P     A P R  
Sbjct: 17  QGRHRHSSRAPGTRTPATPARSPRPPLCAPRPAPGRAQSPVPAAGAVPSPPAAAHPARPA 76

Query: 189 PRPRAPRPGDHPRRSPALRETPSLSPPSP-----GRRNGKRAAGKGTTPQPQP--PPPPC 241
            R   P PG   R +      PS+ PP       G   G+   GKG  P P    PP P 
Sbjct: 77  LRGETPAPGRRGRATTRGEVQPSVRPPLSHRPLRGGGMGRGRPGKGPPPNPSRRLPPAPP 136

Query: 242 ATRREEDMALRTRDRTSSRGT------VFRAADWGFGRSEQHLRGLTLIISCTLSHKPAS 295
             RR    AL T       G       VFRAADWGFGRSEQHLRGLTLIISCTLSHKPAS
Sbjct: 137 GGRRTWLSALATGPAAGGAGRRRRSPPVFRAADWGFGRSEQHLRGLTLIISCTLSHKPAS 196

Query: 296 LRRSGTQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 350
           LRRSGTQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS
Sbjct: 197 LRRSGTQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 251


>gi|239754245 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 160

 Score =  185 bits (470), Expect = 5e-47
 Identities = 89/98 (90%), Positives = 92/98 (93%)

Query: 253 TRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLPLR 312
           T+++      VFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLPLR
Sbjct: 63  TQNKLPRVAAVFRAADWGFGRSEQHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLPLR 122

Query: 313 ATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 350
           ATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS
Sbjct: 123 ATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHSSRS 160


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 62.4 bits (150), Expect = 6e-10
 Identities = 67/231 (29%), Positives = 91/231 (39%), Gaps = 21/231 (9%)

Query: 30  GSRAHPNPRSASSA--AAAASSSFPPPGF-------IHPPSSRAAVHSRLRAAPAAAPRL 80
           G  A P P +A++A  AAAASSS   P +       I    SR A     R       R+
Sbjct: 3   GPPALPPPETAAAATTAAAASSSAASPHYQEWILDTIDSLRSRKARPDLERIC-----RM 57

Query: 81  LPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRP---GPSPPLQPRS-RH 136
           + R     P RT A     ++  A      + +       R +P   G +PP  PR+ R 
Sbjct: 58  VRRRHGPEPERTRAELEKLIQQRAVLRVSYKGSISYRNAARVQPPRRGATPPAPPRAPRG 117

Query: 137 PHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRP 196
                  A P  TP  PPP   P A + P        A +  P   GP +  P PRA R 
Sbjct: 118 APAAAAAAAPPPTPAPPPPPA-PVAAAAPARAPRAAAAAATAPPSPGPAQ--PGPRAQRA 174

Query: 197 GDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREE 247
                  PA    P+++PP+  RR    A      P P PP PP   ++++
Sbjct: 175 APLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQ 225



 Score = 60.1 bits (144), Expect = 3e-09
 Identities = 58/173 (33%), Positives = 64/173 (36%), Gaps = 41/173 (23%)

Query: 76  AAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSR 135
           A P   PR   GAPA           AAAAA     A  PT       P P PP  P + 
Sbjct: 106 ATPPAPPRAPRGAPA-----------AAAAA-----APPPT-------PAPPPPPAPVAA 142

Query: 136 HPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPR 195
               R PRA   A    P PG            + P P   R    A PP     P A  
Sbjct: 143 AAPARAPRAAAAAATAPPSPGP-----------AQPGPRAQRAAPLAAPPPAPAAPPAVA 191

Query: 196 PGDHPRRSP----ALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATR 244
           P   PRR+P    A RE P   PP P     ++   +   PQPQPPP   A R
Sbjct: 192 PPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQ---QPPPPQPQPPPEGGAVR 241



 Score = 59.3 bits (142), Expect = 5e-09
 Identities = 54/168 (32%), Positives = 59/168 (35%), Gaps = 31/168 (18%)

Query: 89  PARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEA 148
           P R GA   +  RA   A     AAAP        P P PP  P +     R PRA   A
Sbjct: 101 PPRRGATPPAPPRAPRGAPAAAAAAAPPPT-----PAPPPPPAPVAAAAPARAPRAAAAA 155

Query: 149 TPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSP---- 204
               P PG            + P P   R    A PP     P A  P   PRR+P    
Sbjct: 156 ATAPPSPGP-----------AQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAV 204

Query: 205 ALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALR 252
           A RE P   PP P              PQ Q PPPP      E  A+R
Sbjct: 205 AAREPPLPPPPQPP-----------APPQQQQPPPPQPQPPPEGGAVR 241



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 60/178 (33%), Positives = 67/178 (37%), Gaps = 38/178 (21%)

Query: 17  AESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAA 76
           A  PA PR            PR A +AAAAA+   PPP    PP           AAPA 
Sbjct: 106 ATPPAPPRA-----------PRGAPAAAAAAA---PPPTPAPPPPPAPVA----AAAPAR 147

Query: 77  APRLLPRVLAGAPARTGALAGSRL-RAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSR 135
           APR         P+   A  G R  RAA  AA     AAP        P  +PP  PR  
Sbjct: 148 APRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAP--------PAVAPPAGPR-- 197

Query: 136 HPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPR--GDPRP 191
                  RA P A   R PP   P     P  +  P P + + P E G  R  G  RP
Sbjct: 198 -------RAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 49/163 (30%), Positives = 60/163 (36%), Gaps = 35/163 (21%)

Query: 5   KATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSA--------AAAASSSFPPPGF 56
           +A   A A    A  P  P         A P P +  +A        AAAA+++ PP   
Sbjct: 113 RAPRGAPAAAAAAAPPPTP---------APPPPPAPVAAAAPARAPRAAAAAATAPPSPG 163

Query: 57  IHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPT 116
              P  RA      RAAP AAP   P     AP      AG R RA   A   +E   P 
Sbjct: 164 PAQPGPRAQ-----RAAPLAAPPPAP----AAPPAVAPPAGPR-RAPPPAVAAREPPLP- 212

Query: 117 GRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRP 159
                  P P PP  P+ + P    P+  PE   +R     RP
Sbjct: 213 -------PPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARP 248



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 67/283 (23%), Positives = 90/283 (31%), Gaps = 68/283 (24%)

Query: 4   EKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSAS---------SAAAAASSSFPPP 54
           ++A   AA PP  A  PA   V    G R  P P  A+            A      PPP
Sbjct: 172 QRAAPLAAPPPAPAAPPA---VAPPAGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPP 228

Query: 55  GFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAA 114
               PP    AV +   A P +  R + R L G+    G L   R++        +E AA
Sbjct: 229 PQPQPPPEGGAVRAGGAARPVSL-REVVRYLGGSGGAGGRLTRGRVQGLL-----EEEAA 282

Query: 115 PTGRRWRRR-----------PGPSPPL--------------------------QPRSRHP 137
             GR  R R           PG +PP                           +      
Sbjct: 283 ARGRLERTRLGALALPRGDRPGRAPPAASARPSRSKRGGEERVLEKEEEEDDDEDEDEED 342

Query: 138 HTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPG 197
                  VPE+   RP      +     G +S+    +  TP   GP +G    R P PG
Sbjct: 343 DVSEGSEVPESD--RPAGAQHHQLNGERGPQSAKERVKEWTP--CGPHQGQDEGRGPAPG 398

Query: 198 DHPRRSPALRETPSLSPPSPGRRNGKRAAGKG-TTPQPQPPPP 239
              R+          S  +  +  G  +   G  +P P P PP
Sbjct: 399 SGTRQ--------VFSMAAMNKEGGTASVATGPDSPSPVPLPP 433


>gi|158854042 hypothetical protein LOC222183 [Homo sapiens]
          Length = 653

 Score = 62.0 bits (149), Expect = 8e-10
 Identities = 67/244 (27%), Positives = 90/244 (36%), Gaps = 46/244 (18%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAA 73
           PG A SP            + P+PR    AAAAA +  PP      PS R+A  S+ R  
Sbjct: 328 PGSAHSPP--------DKPSSPSPRVRDKAAAAAPT--PPARGKESPSPRSAPSSQGRGG 377

Query: 74  PAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPR 133
            AA                   AG R R        + +A+   RR RRRP P+PP   R
Sbjct: 378 RAAGG-----------------AGRRRRRRRRRRRSRSSASAPRRRGRRRPRPAPP---R 417

Query: 134 SRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRA 193
                    R+  ++   R  PG  P   S  G       A+ R      PPR  P   +
Sbjct: 418 GSSRSLSRARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKER------PPRARPASTS 471

Query: 194 PRPGDHPRRSPALRETPSLSPP----------SPGRRNGKRAAGKGTTPQPQPPPPPCAT 243
           P PG H RR     ++ S SP           SP +   + A  +  +P   P P    +
Sbjct: 472 PSPGAHGRRGGPEGKSSSRSPGPHPRSWSSSRSPSKSRSRSAEKRPHSPSRSPSPKKPLS 531

Query: 244 RREE 247
           R ++
Sbjct: 532 RDKD 535



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 68/238 (28%), Positives = 87/238 (36%), Gaps = 48/238 (20%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSASSAAAAAS-------------SSFPPPGFIHP- 59
           PG    P   R +   G RA   P  A  A+ + S             SS   PG  HP 
Sbjct: 439 PGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHGRRGGPEGKSSSRSPG-PHPR 497

Query: 60  --PSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTG 117
              SSR+   SR R+A        P   + +P+    L  SR +     A   EA A   
Sbjct: 498 SWSSSRSPSKSRSRSAEKR-----PHSPSRSPSPKKPL--SRDKDGEGRARHSEAEATRA 550

Query: 118 RRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSR 177
           RR  R    SP  + R   P    PR +  A   RP P  RP   S   C SS +  RS 
Sbjct: 551 RR--RSRSYSPIRKRRRDSPSFMEPRRITSARK-RPIPYYRPSPSSSSSCLSSDYSTRSH 607

Query: 178 TPGEAGPPRGDPRPRAPRP----GDHPRRSPALR---ETPSLSP-PSPGRRNGKRAAG 227
           +             R+P P    G +  RS   R    +PS +P PS   R+   + G
Sbjct: 608 S-------------RSPSPGHSHGSYSSRSHGTRSRTRSPSRTPSPSYHSRSSSESGG 652



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 34/175 (19%), Positives = 55/175 (31%), Gaps = 14/175 (8%)

Query: 93  GALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLR 152
           G+ +  R +  +   H ++ +    RR RR    S   + + ++   + P          
Sbjct: 194 GSSSPLRKKKKSVKKHRRDRSDSGSRRKRRHRSRSSKCKRKEKNKEKKRPHT-------- 245

Query: 153 PPPGTRPRAKSRPGCRSSPFPAR---SRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRET 209
             PG R    S     S    +    SR+P    P   D   +         RSP+    
Sbjct: 246 ESPGRRSHRHSSGSSHSPSLSSHYSDSRSPSRLSPKHRDEGRKTGSQRSSGSRSPSPSGG 305

Query: 210 PSLSPPSPGRRNGKRAAGKGTTP---QPQPPPPPCATRREEDMALRTRDRTSSRG 261
                P     +G+R+   G  P      P  P   + R  D A        +RG
Sbjct: 306 SGWGSPQRNGGSGQRSGAHGGRPGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARG 360



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 45/174 (25%), Positives = 58/174 (33%), Gaps = 12/174 (6%)

Query: 159 PRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDH-----PRRSPALRETPS-L 212
           P+     G RS     R   PG A  P   P   +PR  D      P      +E+PS  
Sbjct: 311 PQRNGGSGQRSGAHGGR---PGSAHSPPDKPSSPSPRVRDKAAAAAPTPPARGKESPSPR 367

Query: 213 SPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFG 272
           S PS   R G+ A G G   + +         R    A R R R   R    R +     
Sbjct: 368 SAPSSQGRGGRAAGGAGRRRRRRRRR---RRSRSSASAPRRRGRRRPRPAPPRGSSRSLS 424

Query: 273 RSEQHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLPLRATPESFKGSPDCTG 326
           R+       +   +     +P S R  G      +  P RA P S   SP   G
Sbjct: 425 RARSSSDSGSGRGAPGPGPEPGSERGHGGHGKRAKERPPRARPASTSPSPGAHG 478


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 60.5 bits (145), Expect = 2e-09
 Identities = 61/233 (26%), Positives = 80/233 (34%), Gaps = 30/233 (12%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSAS-------SAAAAASSSFPPPGFIHPPSSRAAV 66
           P V   PA P       ++  P P  ++       +AAA A+   P P     P+  AA+
Sbjct: 113 PLVPAGPAPP------AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166

Query: 67  HSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGP 126
            +R    P   P   P    G PA  GA     L  +AA  +   AAAP        P  
Sbjct: 167 AARAGPGPGPGPGPGPGPGPGKPAGPGA--AQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224

Query: 127 SPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPR 186
             PL           P+     T ++ PP     A   P   S P       P  A PP 
Sbjct: 225 LLPL-----------PKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPP 273

Query: 187 GDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPP 239
                   RP  HP   P     P++ PP+  +  G  +AG    P P    P
Sbjct: 274 PPAPATLARPPGHPAGPPT--AAPAVPPPAAAQNGG--SAGAAPAPAPAAGGP 322



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 71/238 (29%), Positives = 93/238 (39%), Gaps = 37/238 (15%)

Query: 11  AAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAA---AASSSFPPPGFIHPPSSRAAVH 67
           AAP  V ++P  P V    G+ A P P + S  AA   AA ++ PPP    PP + A + 
Sbjct: 232 AAPGTVIQTP--PFV----GAAAPPAPAAPSPPAAPAPAAPAAAPPP----PPPAPATL- 280

Query: 68  SRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPG-- 125
           +R    PA  P   P V   A A+ G  AG      AA A    A  P G   +  PG  
Sbjct: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAG------AAPAPAPAAGGPAGVSGQPGPGAA 334

Query: 126 ---PSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEA 182
              P+P ++  S       P+ V +A     PP  +  A S P   ++         G  
Sbjct: 335 AAAPAPGVKAES-------PKRVVQAA----PPAAQTLAASGPASTAASMVIGPTMQGAL 383

Query: 183 GPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240
             P   P P    P   P +  A   T SLS       +G RA    T   P+ P PP
Sbjct: 384 PSPAAVPPPAPGTPTGLP-KGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPP 440



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 71/282 (25%), Positives = 87/282 (30%), Gaps = 48/282 (17%)

Query: 6   ATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPP-PGFIHPPSSRA 64
           A   AA P      PA+P       +RA P P              P  PG     +  A
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSA 202

Query: 65  AV-HSRLRAAPAAA------PRLLPRVLAGAPA---RTGALAGSRLRAAAAAAHDQEAAA 114
           A+ +S   AAPA +        LLP     AP    +T    G+    A AA     A A
Sbjct: 203 ALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPA 262

Query: 115 PTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPA 174
           P        P P PP       P   +P   P A P  PPP       S  G   +P PA
Sbjct: 263 PAAPA--AAPPPPPPAPATLARP-PGHPAGPPTAAPAVPPPAAAQNGGSA-GAAPAPAPA 318

Query: 175 RSRTPGEAGPPRGDPRPRAPRPG---DHPRR----------------------------- 202
                G +G P       AP PG   + P+R                             
Sbjct: 319 AGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPT 378

Query: 203 -SPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCAT 243
              AL    ++ PP+PG   G      G   Q     P   T
Sbjct: 379 MQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATT 420



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 49/180 (27%), Positives = 61/180 (33%), Gaps = 27/180 (15%)

Query: 65  AVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRP 124
           ++ S+L A+ A    L PR      A  GAL    +  + A A     AAP        P
Sbjct: 28  SLESQLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAP 87

Query: 125 GPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGP 184
            P P  + R      + P       PL P     P AK RP                  P
Sbjct: 88  EPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP------------------P 129

Query: 185 PRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRA----AGKGTTPQPQPPPPP 240
           P G     AP P      + A+   P  +P  P +  G  A    AG G  P P P P P
Sbjct: 130 PEGSAGSCAPVPA-----AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGP 184


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 61/215 (28%), Positives = 76/215 (35%), Gaps = 24/215 (11%)

Query: 30  GSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAP 89
           G       RSA SA A   +S P PG    PS   A  SR        PR  P      P
Sbjct: 136 GKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192

Query: 90  ARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQ-PRSRHPHTRYPRAVPEA 148
                  G R   ++A+ H     +P  RR   RP     LQ P SR   +        A
Sbjct: 193 TE-----GPRKSVSSASEHSTTEPSPAARR---RPSAGGGLQRPASRSLSS-------SA 237

Query: 149 TPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRE 208
           TPL  P  + P A+  P   + P   + +      PP+  P  +   P   P  S  L  
Sbjct: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 297

Query: 209 TPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCAT 243
               +PPSP      +     T P P   PP  AT
Sbjct: 298 PSPSAPPSPSAPPSLQ-----TLPSPPATPPSQAT 327



 Score = 55.1 bits (131), Expect = 9e-08
 Identities = 74/271 (27%), Positives = 95/271 (35%), Gaps = 48/271 (17%)

Query: 3   REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
           R+   E A    G     + PR      SR   + R   +  A  +S    PG   P SS
Sbjct: 55  RKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTS----PG---PVSS 107

Query: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
                   R  P     L  R+ A      G    +  R+A +A   ++ + PT      
Sbjct: 108 PGRASGTTRPGPLGQKGL--RISAEETVARGKATEAPKRSALSAGARRDTSGPT------ 159

Query: 123 RPG-PSPPLQPRSRHPHTRY--PRAVPEATPLRPPPGTRPRAKS-RPGCRSSPFPARSRT 178
            PG PSP +  RSR   T    PR  P A P  P  G R    S      + P PA  R 
Sbjct: 160 -PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218

Query: 179 PGEAG-------------------PPRGDPRPR-APRPGDHPRRSPALRETPSLSPP--S 216
           P   G                   P R  P  R  PR   HP + P  +   +L PP  +
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKGLQALRPPQVT 277

Query: 217 PGRRNGKRAAGKGT-----TPQPQPPPPPCA 242
           P R++   A G  +     TP P  PP P A
Sbjct: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSA 308



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 70/278 (25%), Positives = 97/278 (34%), Gaps = 53/278 (19%)

Query: 6   ATEEAAAPPGVA----ESPARPRVNEQWGSRAHPNPRSASSAAA-AASSSFPPPGFIHPP 60
           AT    APP +A    ++P  P  +      A P+P++ ++ A     + F PP     P
Sbjct: 351 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-----P 405

Query: 61  SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW 120
           S            P  AP   P   A  P    A   S+   + AA   Q   +P     
Sbjct: 406 SP-----------PVQAPFSPP---ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--- 448

Query: 121 RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG 180
                 SPP+ P +  P    P        L  PP   P A + P  ++ P P  S  PG
Sbjct: 449 ------SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPG 501

Query: 181 EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ----- 235
           +A        P +P     P+  P L       PPSP      +A  +  TP P      
Sbjct: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561

Query: 236 ----------PPPP----PCATRREEDMALRTRDRTSS 259
                     PPPP    P +T    D+A  +   TS+
Sbjct: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 599



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 77/283 (27%), Positives = 100/283 (35%), Gaps = 57/283 (20%)

Query: 5   KATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASS---SFP-----PPGF 56
           K+   A+       SPA  R     G    P  RS SS+A   SS   S P     P   
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257

Query: 57  IHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPT 116
            HP   +      LR      P++ P     APA  G L+ S L   + +A    +A P+
Sbjct: 258 AHPSQPKPKGLQALRP-----PQVTPPRKDAAPA-LGPLSSSPLATPSPSAPPSPSAPPS 311

Query: 117 GRRWRRRPGPSPPLQ-------PRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRS 169
            +     P  +PP Q       P  +  H+  P   P  +PL  PP   P A + P  ++
Sbjct: 312 LQTLPSPPA-TPPSQATTSLGSPTLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQA 368

Query: 170 SPFPARS------RTPGEAGP-------------PRGDPRPRAP-----RPGDHPRRSPA 205
            P P  S       TP    P             P   P  +AP      P   P  +P 
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428

Query: 206 LRETPSLS------PPSPGRRNGKRAAGKGTTPQPQPPPPPCA 242
            +  PSL+      PPSP             TP PQ PPP  A
Sbjct: 429 SQAPPSLAAPPLQVPPSP---PASPPMSPSATPPPQAPPPLAA 468



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 70/298 (23%), Positives = 92/298 (30%), Gaps = 79/298 (26%)

Query: 6   ATEEAAAPPGVAESPAR----PRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHP-- 59
           AT  + APP +A  P +    P  +      A P P++    AA       PP    P  
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484

Query: 60  --------PSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQE 111
                   PS  A+   +   +P+A+  + P  LA  P +   +    L A         
Sbjct: 485 ATPPLQALPSPPASFPGQAPFSPSASLPMSP--LATPPPQAPPV----LAAPLLQVPPSP 538

Query: 112 AAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPG----- 166
            A+PT +  RR P P P             PR      P  PPP +R  + +  G     
Sbjct: 539 PASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591

Query: 167 ----CRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPR---RSPA------------LR 207
                 S+P   R    G  G     P P A     HP    R PA            L 
Sbjct: 592 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 651

Query: 208 ETPSLSP----------------------------PSPGRRNGKRAAGKGTTPQPQPP 237
             P+  P                            PSPG   GK AAG G     + P
Sbjct: 652 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 59.7 bits (143), Expect = 4e-09
 Identities = 89/356 (25%), Positives = 132/356 (37%), Gaps = 71/356 (19%)

Query: 3    REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
            +E   + +A+P   +ES + P    +  +      RS SS    + S       + P  S
Sbjct: 1543 QELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR------LSPRRS 1596

Query: 63   RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
            R+     ++  P AAPR          A++G+ +    +A A  A  + + + +  + R 
Sbjct: 1597 RSGSSPEVKDKPRAAPR----------AQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR- 1645

Query: 123  RPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFP-ARSRTPGE 181
              GPSP     +            E++P  PP        +R G RSSP P  +SRTP  
Sbjct: 1646 --GPSPEGSSST------------ESSPEHPPKSRT----ARRGSRSSPEPKTKSRTPPR 1687

Query: 182  AGPPRGDP------------RPRAPRPGDHPRRSPALRETPSLSPPSPGRRNG------- 222
                R  P            R  +  P    R  P  R +PS+S P P  ++        
Sbjct: 1688 RRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRS 1747

Query: 223  ------KRAAGKGTTPQPQP---PPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFGR 273
                  K  + +G +P P+P         +RRE+    R RDR+ S  +  R       R
Sbjct: 1748 ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR 1807

Query: 274  SE--QHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLPLRATPESFKGSPDCTGP 327
            S   +  RG     S   S  PA    S T +   RG   R  P S K S   T P
Sbjct: 1808 SRVTRRRRG----GSGYHSRSPARQESSRTSSRRRRGRS-RTPPTSRKRSRSRTSP 1858



 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 94/363 (25%), Positives = 140/363 (38%), Gaps = 40/363 (11%)

Query: 3    REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
            RE+++  A++P      P  P    + GS   P  R  S   +  S S   PG    P +
Sbjct: 1416 RERSSS-ASSPEMKDGLPRTPSRRSRSGSS--PGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472

Query: 63   RAAVHSRLRAAPAA-----APRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTG 117
             +   S   ++P        PR   R  +        L   R R+ + ++ DQ+  A T 
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532

Query: 118  RRWRRRPGPS------PPLQPRSRHPHTRYPRAVPEA-TPL--RPPPGTRPRAKSRPGCR 168
               R R G S      P   P+ R      P +  +  TPL  R   G+ P   S+   R
Sbjct: 1533 LGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSK--SR 1590

Query: 169  SSPFPARS-RTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAG 227
             SP  +RS  +P     PR  PR ++        ++PA R  P  S      R+G  + G
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS------RSGSSSKG 1644

Query: 228  KGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISC 287
            +G       P P  ++  E       + RT+ RG+  R++     +S    R  +   S 
Sbjct: 1645 RG-------PSPEGSSSTESSPEHPPKSRTARRGS--RSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 288  TLSHKPASLRRSGTQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSLERRPAHS 347
             L+ K    RRS + +  P       TP   + SP  + PE     E  RSS  RR A S
Sbjct: 1696 ELTRKARLSRRSRSASSSPE--TRSRTPPRHRRSPSVSSPE---PAEKSRSSRRRRSASS 1750

Query: 348  SRS 350
             R+
Sbjct: 1751 PRT 1753



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 68/249 (27%), Positives = 94/249 (37%), Gaps = 29/249 (11%)

Query: 22  RPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA---APAAAP 78
           R R  ++WG       RS S      S S   PG+    +++    SR      + + +P
Sbjct: 515 RSRSAQRWG-------RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSP 567

Query: 79  RLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRP----GPSPPLQPRS 134
               R  +  PAR G     R R+   A     +  PT RR R R     G S    P  
Sbjct: 568 ATRGRSRSRTPARRG-----RSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPAR 622

Query: 135 RHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAP 194
           R   TR P  V   +  R P     R++SR   R     +RSRTP   G  R   R  A 
Sbjct: 623 RRSRTRSP--VRRRSRSRSPARRSGRSRSRTPARRGR--SRSRTPARRGRSRS--RTPAR 676

Query: 195 RPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKG----TTPQPQPPPPPCATRREEDMA 250
           R G    R+PA R       P  GR   +    +G     TPQ +      + R+ +   
Sbjct: 677 RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRT 736

Query: 251 LRTRDRTSS 259
            + R R++S
Sbjct: 737 SQRRSRSNS 745



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 71/265 (26%), Positives = 96/265 (36%), Gaps = 42/265 (15%)

Query: 10   AAAPPGV----AESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSR-- 63
            A AP  V      +P  P VN      A     +A +A +   S  PP    +P SSR  
Sbjct: 2276 AVAPSAVNLADPRTPTAPAVN-----LAGARTPAALAALSLTGSGTPPTAANYPSSSRTP 2330

Query: 64   -AAVHSRL---RAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRR 119
             A   + L   R+A A AP  +      A     +L  +R+  A + A+      P    
Sbjct: 2331 QAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAY 2390

Query: 120  WRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTP 179
             R     SPPL  R+R   +R P + P  + +     T  RA S P  R    P++S  P
Sbjct: 2391 ERVSGRTSPPLLDRAR---SRTPPSAPSQSRM-----TSERAPS-PSSRMGQAPSQSLLP 2441

Query: 180  GEAGPPRGDPRPRA-------------PRPGDHPRRSPALRETPSLSPPSPGRRNGKRAA 226
                 PR  P P A             P  G     S A+  T S    S G  NG  + 
Sbjct: 2442 PAQDQPR-SPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS----SAGDHNGMLSV 2496

Query: 227  GKGTTPQPQPPPPPCATRREEDMAL 251
                 P      PP +T  ++  AL
Sbjct: 2497 PAPGVPHSDVGEPPASTGAQQPSAL 2521



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 75/310 (24%), Positives = 108/310 (34%), Gaps = 61/310 (19%)

Query: 74  PAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAA--APTGRRWRRRPGPSPPLQ 131
           PA   R   R  +   A +   + SR R+AAA  H    A  +P+    RR  G +P  +
Sbjct: 253 PAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSE 312

Query: 132 PRSRHPHTRYPRAVPEAT--PLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPR--- 186
           P +    T+ P +   AT  P  P        K +   R SP P RS T  E   P    
Sbjct: 313 PGTTS--TQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLL 370

Query: 187 -----GDPRPRAPRPGDHPRRSPALRETPSL-------------------SPPSPG-RRN 221
                G P+P A  P      +P    +P+                    SPPSP   + 
Sbjct: 371 AERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKV 430

Query: 222 GKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGL 281
            + A+    +P+P P P    + RE   +  +++R+  R            R + H    
Sbjct: 431 SRHASSSPESPKPAPAP---GSHREISSSPTSKNRSHGRAK----------RDKSH---- 473

Query: 282 TLIISCTLSHKPA-SLRRSGTQAWGPRGLPLRATPESFKGSPDCTGPEIGFDMELLRSSL 340
                   SH P+  + RS + A   RG     TP   +G      P+        R   
Sbjct: 474 --------SHTPSRRMGRSRSPATAKRGRSRSRTPTK-RGHSRSRSPQWRRSRSAQRWGR 524

Query: 341 ERRPAHSSRS 350
            R P    RS
Sbjct: 525 SRSPQRRGRS 534



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 56/242 (23%), Positives = 94/242 (38%), Gaps = 20/242 (8%)

Query: 6    ATEEAAAPPGVAE-SPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRA 64
            A+  A  P  +A   PA+ R +    S +  +  S+SS+++++SSS          S   
Sbjct: 2511 ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPV 2570

Query: 65   AVHSRLRAAPAAAPRLLPRVLAGAP--------ARTGALAGSRLRAAAAAAHDQEAAAPT 116
                 L+  P+  P     V  G P         R  + + S   ++++++    +++ +
Sbjct: 2571 QPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSS 2630

Query: 117  GRRWRRRPGPSPPLQPRSRHPHTRYPRAVPE-ATPLRPPPG-TRPRAKSRPGCRSSPFPA 174
                      S      S  P    P+A+P+ A+P +PPPG  R R+  +P        +
Sbjct: 2631 SSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRS 2690

Query: 175  RSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQP 234
             S +P E   P   P PR  +     R S   +   S SP    RR          TP P
Sbjct: 2691 LSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRE---------TPSP 2741

Query: 235  QP 236
            +P
Sbjct: 2742 RP 2743



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 78/321 (24%), Positives = 107/321 (33%), Gaps = 54/321 (16%)

Query: 7   TEEAAAPPGVAESPAR-----------PRVNEQWGSRAHPNPRSASSAAAAASSS---FP 52
           ++E   PP  A SP R           P+ +    S   P P   S  A+++  S    P
Sbjct: 387 SQEPVNPPSEA-SPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAP 445

Query: 53  PPG----FIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAH 108
            PG        P+S+   H R +   + +     R+       T     SR R      H
Sbjct: 446 APGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505

Query: 109 DQEAA-----APTGRRWRRRPGPS------PPLQP---RSRHPHTR-YPRAVPEATPLRP 153
            +  +     + + +RW R   P        P +P   RSR+   R   R+         
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565

Query: 154 PPGTRPRAKSRPGCRS--------------SPFPARSRTPGEAGPPRGDPRPRAPRPGDH 199
            P TR R++SR   R               S  P R R+       RG  R R P     
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625

Query: 200 PRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSS 259
             RSP  R + S    SP RR+G+    +  TP  +         R      RT  R S 
Sbjct: 626 RTRSPVRRRSRS---RSPARRSGR---SRSRTPARRGRSRSRTPARRGRSRSRTPARRSG 679

Query: 260 RGTVFRAADWGFGRSEQHLRG 280
           R      A  G  RS    RG
Sbjct: 680 RSRSRTPARRGRSRSRTPRRG 700



 Score = 42.4 bits (98), Expect = 6e-04
 Identities = 68/250 (27%), Positives = 100/250 (40%), Gaps = 40/250 (16%)

Query: 23  PRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRL-L 81
           P+   + GS +    +S +S   + S+S P        S R+   S  R+   A  RL L
Sbjct: 718 PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSK--AKSRLSL 775

Query: 82  PRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTR- 140
            R L+G+       + +  R + + +   +A + T  R R R   SPP + +S+ P  + 
Sbjct: 776 RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-RSRSSSSPPPKQKSKTPSRQS 834

Query: 141 ------YPRAVPEATPLRPPPGTRPRAKS------RPGC-RSSPFPA-RSRTPGE----- 181
                 +P+ V   TP R    T P+A        R  C  SSP P  +SRTP       
Sbjct: 835 HSSSSPHPK-VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSG 893

Query: 182 --------AGPPRGDP-RPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTP 232
                   + PPR  P R  +P+P      SP  R     S PSP R   +      TTP
Sbjct: 894 SSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSR------TTP 947

Query: 233 QPQPPPPPCA 242
           +      PC+
Sbjct: 948 RRSRSVSPCS 957



 Score = 40.8 bits (94), Expect = 0.002
 Identities = 89/353 (25%), Positives = 125/353 (35%), Gaps = 42/353 (11%)

Query: 33   AHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVH--SRLRAAPAAAPRLLPRVLAGAPA 90
            A P P  +++  AA  S  P P  +    +  A +  SR+ AA AAA  L        P 
Sbjct: 2193 ARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPT 2252

Query: 91   RTGALAGSRLRAAAAA---AHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPE 147
                LA SR  AAAAA   A  + A AP+         P  P  P       R P A+  
Sbjct: 2253 AVN-LADSRTPAAAAAMNLASPRTAVAPSA---VNLADPRTPTAPAVNLAGARTPAAL-- 2306

Query: 148  ATPLRPPPGTRPRAKSRPGCRSSP-FPARSRTPGEAGPPRGDP---------RPRAPRPG 197
            A       GT P A + P    +P  PA +   G        P            AP   
Sbjct: 2307 AALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366

Query: 198  DHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTP------QPQPPPPPCATRREEDMAL 251
               R +PAL      SP  P     +R +G+ + P         PP  P  +R   + A 
Sbjct: 2367 TSARMAPALSGANLTSPRVP-LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAP 2425

Query: 252  RTRDR---TSSRGTVFRAADW-------GFGRSEQHLRGLTLIISCTLSHKPASLRRSGT 301
                R     S+  +  A D         F    + L   T  ++ + S    ++  + +
Sbjct: 2426 SPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS 2485

Query: 302  QAWGPRGL---PLRATPESFKGSPDC-TGPEIGFDMELLRSSLERRPAHSSRS 350
             A    G+   P    P S  G P   TG +    +  L+ + ERR + SS S
Sbjct: 2486 SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSS 2538



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 67/280 (23%), Positives = 94/280 (33%), Gaps = 47/280 (16%)

Query: 13   PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
            PP    SP+         SR+    RSASS     +S     G    P  R    SR R+
Sbjct: 1721 PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR---RGRSPSPKPRGLQRSRSRS 1777

Query: 73   APAAAPRLLPRVLAGAPARTGAL---------------AGSRLRAAAAAAHDQEAAAPTG 117
                      R  +G+   T                   GS   + + A  +    +   
Sbjct: 1778 RREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRR 1837

Query: 118  RRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSR 177
            RR R R  P+   + RSR     + R+   A+     P T  R++SR     +P  +R R
Sbjct: 1838 RRGRSRTPPTSRKRSRSRTSPAPWKRSRSRAS-----PATHRRSRSR-----TPLISRRR 1887

Query: 178  TPGEAGP---PRGDPRPRAPRPGDHPRRSP-ALRETPSLSPPSPGRRNGKRAAGKGTTPQ 233
            +     P    R   R    R     R SP + R + S +PP   RR+  R        +
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947

Query: 234  PQPPP----------PPCATRREEDMA-----LRTRDRTS 258
             + PP          PP   RR           R+R RTS
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS 1987



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 24/73 (32%), Positives = 32/73 (43%), Gaps = 6/73 (8%)

Query: 173  PARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRE---TP---SLSPPSPGRRNGKRAA 226
            P+R R+   + P   D  PR P        SP LR+   TP   SLS  SPG ++  R  
Sbjct: 1414 PSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP 1473

Query: 227  GKGTTPQPQPPPP 239
             +G +     P P
Sbjct: 1474 SRGRSECDSSPEP 1486



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 53/218 (24%), Positives = 74/218 (33%), Gaps = 24/218 (11%)

Query: 17   AESPARPRVNEQWGSRAHP----NPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
            + S A P    +  SR  P      RS +      S S  PP       SR    +R R+
Sbjct: 1911 SRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRS 1970

Query: 73   APAAAP--------RLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRP 124
                +P        R  P     + +RT  +   R R+  +    + + + T    RRR 
Sbjct: 1971 RSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRS 2030

Query: 125  GPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGP 184
                PL PR R   +R P A+   +  R P   R +   R   RS P   R    G +  
Sbjct: 2031 RSRTPLLPRKR-SRSRSPLAIRRRSRSRTPRTARGK---RSLTRSPPAIRRRSASGSSSD 2086

Query: 185  PRGDPRPRAPRPGDHPRRSPALRET--------PSLSP 214
                  P A R     R  P    +        PS+SP
Sbjct: 2087 RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSP 2124



 Score = 31.2 bits (69), Expect = 1.4
 Identities = 47/231 (20%), Positives = 79/231 (34%), Gaps = 45/231 (19%)

Query: 39   SASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGA-PA---RTGA 94
            S+ + A   SS+    G +  P+     HS +   PA+     P  LA   PA   R+ +
Sbjct: 2476 SSGAVATTTSSAGDHNGMLSVPAP-GVPHSDVGEPPASTGAQQPSALAALQPAKERRSSS 2534

Query: 95   LAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPP 154
             + S   ++++++    +++ +G       G S P+QP              E    R P
Sbjct: 2535 SSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQP--------------EVALKRVP 2580

Query: 155  PGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSP 214
                           SP PA      E  PP   P  R  R       S +   + S S 
Sbjct: 2581 ---------------SPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSS 2625

Query: 215  PSPGRRNGKRAAGKGTT-----------PQPQPPPPPCATRREEDMALRTR 254
             S    +   ++   ++           P PQ  P P + ++      R+R
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSR 2676



 Score = 30.0 bits (66), Expect = 3.2
 Identities = 34/141 (24%), Positives = 54/141 (38%), Gaps = 34/141 (24%)

Query: 6    ATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAA 65
            ++  +++    + SPA+P      G +A P P         AS   PPPG     S R  
Sbjct: 2637 SSSSSSSSSSSSPSPAKP------GPQALPKP---------ASPKKPPPGERRSRSPRKP 2681

Query: 66   VHS-----RLRAAPAA----APRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPT 116
            + S      L  +P      +P+  PR    + +  G+  G R           ++ +P+
Sbjct: 2682 IDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQR----------GDSRSPS 2731

Query: 117  GRRWRRRPGPSPPLQPRSRHP 137
             +R R  P P P     SR P
Sbjct: 2732 HKRRRETPSPRPMRHRSSRSP 2752


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 62/221 (28%), Positives = 80/221 (36%), Gaps = 26/221 (11%)

Query: 30  GSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAP 89
           G       RSA SA A   +S P PG    PS   A  SR        PR  P      P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 90  ARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQ-PRSRHPHTRYPRAVPEA 148
                  G R   ++A+ H     +P  RR   RP     LQ P SR   +        A
Sbjct: 202 TE-----GPRKSVSSASEHSTTEPSPAARR---RPSAGGGLQRPASRSLSS-------SA 246

Query: 149 TPLRPPPGTRPRAKSRPGCRSSPFPARSR-----TPGEAGPPRGDPRPRAPRPGDHPRRS 203
           TPL  P  + P A+  P   + P   + +      P +  PPR D  P        P  +
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 204 PA-LRETPSLSPPS-PGRRNGKRAAGKGTTPQPQPPPPPCA 242
           P+      S +PP+ P   +      +  TP P  PP P A
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 70/278 (25%), Positives = 97/278 (34%), Gaps = 53/278 (19%)

Query: 6   ATEEAAAPPGVA----ESPARPRVNEQWGSRAHPNPRSASSAAA-AASSSFPPPGFIHPP 60
           AT    APP +A    ++P  P  +      A P+P++ ++ A     + F PP     P
Sbjct: 390 ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP-----P 444

Query: 61  SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW 120
           S            P  AP   P   A  P    A   S+   + AA   Q   +P     
Sbjct: 445 SP-----------PVQAPFSPP---ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--- 487

Query: 121 RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG 180
                 SPP+ P +  P    P        L  PP   P A + P  ++ P P  S  PG
Sbjct: 488 ------SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPAS-FPG 540

Query: 181 EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ----- 235
           +A        P +P     P+  P L       PPSP      +A  +  TP P      
Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600

Query: 236 ----------PPPP----PCATRREEDMALRTRDRTSS 259
                     PPPP    P +T    D+A  +   TS+
Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 72/272 (26%), Positives = 96/272 (35%), Gaps = 66/272 (24%)

Query: 40  ASSAAAAASSSFPPPGFI--HPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPA------- 90
           A + AAA + +   PG +   PP S        R  P   P  L RVL  A A       
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPPGSP-------RPPPPVTPAAL-RVLGAAGAVGRKPLA 59

Query: 91  -RTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRS-RHPHTRYPRAVPEA 148
            R G + G+ +  +A  A    +A  + R     P   PP   R  R P  +     P +
Sbjct: 60  ERAGGIGGATIPESAPRAGPTRSAGTSSRN----PASRPPASGRGERAPPAKNTSPGPVS 115

Query: 149 TPLRPPPGTRPRAKSRPGCRSS----------------------------------PFPA 174
           +P R    TRP    + G R S                                  P PA
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175

Query: 175 ---RSRTPG-EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGT 230
              RSR  G E G PR  P  R   P + PR+S +     S + PSP  R  + +AG G 
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGL 234

Query: 231 TPQPQPPPPPCATRREEDMALRTRDRTSSRGT 262
               Q P     +     ++   R   S+RGT
Sbjct: 235 ----QRPASRSLSSSATPLSSPARSGPSARGT 262



 Score = 45.8 bits (107), Expect = 6e-05
 Identities = 65/260 (25%), Positives = 85/260 (32%), Gaps = 53/260 (20%)

Query: 31  SRAHPNPRSASSAAAAASSSFP-------PPGFIHPPSSRAAVHSRLRAAPAAAPRLLPR 83
           +R+ P+ R    A A  S   P       PP    P    A     L ++P A P     
Sbjct: 253 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAA 312

Query: 84  VLAGAPARTGALAGSRLRAAAAAAH----DQEAAAPTGRRWRRRPGPSPPLQ-------P 132
           + + AP    A   S       A          +AP   +    P  +PP Q       P
Sbjct: 313 LQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 372

Query: 133 RSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARS------RTPGEAGP-- 184
             +  H+  P   P  +PL  PP   P A + P  ++ P P  S       TP    P  
Sbjct: 373 TLQATHSFLPS--PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 430

Query: 185 -----------PRGDPRPRAP-----RPGDHPRRSPALRETPSLS------PPSPGRRNG 222
                      P   P  +AP      P   P  +P  +  PSL+      PPSP     
Sbjct: 431 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP---PA 487

Query: 223 KRAAGKGTTPQPQPPPPPCA 242
                   TP PQ PPP  A
Sbjct: 488 SPPMSPSATPPPQAPPPLAA 507



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 70/298 (23%), Positives = 92/298 (30%), Gaps = 79/298 (26%)

Query: 6   ATEEAAAPPGVAESPAR----PRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHP-- 59
           AT  + APP +A  P +    P  +      A P P++    AA       PP    P  
Sbjct: 464 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 523

Query: 60  --------PSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQE 111
                   PS  A+   +   +P+A+  + P  LA  P +   +    L A         
Sbjct: 524 ATPPLQALPSPPASFPGQAPFSPSASLPMSP--LATPPPQAPPV----LAAPLLQVPPSP 577

Query: 112 AAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPG----- 166
            A+PT +  RR P P P             PR      P  PPP +R  + +  G     
Sbjct: 578 PASPTLQAPRRPPTPGPDTSVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630

Query: 167 ----CRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPR---RSPA------------LR 207
                 S+P   R    G  G     P P A     HP    R PA            L 
Sbjct: 631 HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLP 690

Query: 208 ETPSLSP----------------------------PSPGRRNGKRAAGKGTTPQPQPP 237
             P+  P                            PSPG   GK AAG G     + P
Sbjct: 691 WPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 748


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 58.9 bits (141), Expect = 6e-09
 Identities = 62/251 (24%), Positives = 89/251 (35%), Gaps = 25/251 (9%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
           PPG  + P     N+   SR+ P                PPP    PP        +   
Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP----PPGKPQGPPPQGGN 210

Query: 73  APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
            P   P        G P        ++ ++A +     +   P G    + P P PP +P
Sbjct: 211 KPQGPPP------PGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP-PPPPGKP 263

Query: 133 RSRHPH--TRYPRAVPEATPLRPPP--GTRPRA-KSRPGCRSSPFPARSRTPGEAGPPRG 187
           +   P    +     P   P  PPP  G++ R+ +S PG    P P     P    PP G
Sbjct: 264 QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323

Query: 188 DPRPRAPRPGDHPRRSPALRETPSLSPPSPGR--RNGKRAAGKGTTP------QPQPPPP 239
            P+   P+ G+ P+  P   + P   PP  G   R+ +   GK   P       PQ PPP
Sbjct: 324 KPQGPPPQGGNKPQGPPPPGK-PQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382

Query: 240 PCATRREEDMA 250
           P     ++  A
Sbjct: 383 PAGGNPQQPQA 393



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 59/244 (24%), Positives = 83/244 (34%), Gaps = 31/244 (12%)

Query: 12  APPGVAESPARPRVNEQWGSRAHPN-PRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRL 70
           +PPG  + P     N+  G    P  P+             PPPG    P  +    SR 
Sbjct: 113 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS 172

Query: 71  RAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPL 130
             +P   P+       G P +     G++ +         +   P G    +  GP PP 
Sbjct: 173 SRSPPGKPQ-------GPPPQ----GGNQPQGPPPPPGKPQGPPPQGGN--KPQGPPPPG 219

Query: 131 QPRSRHP---HTRYPRAVPEATPLRPPP--GTRPRAKSRPGCRSSPFPARSRTPGEAGPP 185
           +P+   P   +       P   P  PPP  G +P+    P  +    P +     +  PP
Sbjct: 220 KPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP 279

Query: 186 RGDPRPRAPRPGDHPRRS-----------PALRETPSLSPPSPGRRNGKRAAGKGTTPQP 234
            G P+   P+ G   R S           P     P   PP PG+  G    G G  PQ 
Sbjct: 280 PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG-GNKPQG 338

Query: 235 QPPP 238
            PPP
Sbjct: 339 PPPP 342



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 48/182 (26%), Positives = 69/182 (37%), Gaps = 35/182 (19%)

Query: 82  PRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPH--T 139
           P ++AG P       G++ +   +     +   P G    + P P PP +P+   P    
Sbjct: 29  PSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP-PPPPGKPQGPPPQGGN 87

Query: 140 RYPRAVPEATPLRPPP-GTRPRA-KSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPG 197
           +     P   P  PPP G + R+ +S PG    P P     P    PP G P+   P+ G
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147

Query: 198 DHPRRSPALRETPSLSPPSPGR------------RNGKRAAGKGTTPQPQ-------PPP 238
           + P+            PP PG+            R+ +   GK   P PQ       PPP
Sbjct: 148 NKPQ-----------GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP 196

Query: 239 PP 240
           PP
Sbjct: 197 PP 198



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 43/130 (33%), Positives = 54/130 (41%), Gaps = 18/130 (13%)

Query: 125 GPSPPLQPRSRHPH---TRYPRAVPEATPLRPPP--GTRPRAKSRP-GCRSSPFPARSRT 178
           GP PP +P+   P    +R PR+ P   P  PPP  G +P+    P G    P P     
Sbjct: 91  GPPPPGKPQGPPPQGDKSRSPRS-PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 149

Query: 179 PG--------EAGPPRGDPRPRAPR--PGDHPRRSPALRETPSLSPPSPGRRNGKRAAGK 228
           P         +  PP+GD + R+ R  PG      P     P   PP PG+  G    G 
Sbjct: 150 PQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG- 208

Query: 229 GTTPQPQPPP 238
           G  PQ  PPP
Sbjct: 209 GNKPQGPPPP 218



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 54/247 (21%), Positives = 81/247 (32%), Gaps = 18/247 (7%)

Query: 4   EKATEEAAAPPGVAESPARPRVNEQWGSRAHPN-PRSASSAAAAASSSFPPPGFIHPPSS 62
           +  +  + +PPG  + P     N+  G    P  P+             PPPG    P  
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 226

Query: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
           +    S+   +P   P+  P      P       G          +  +   P G+    
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--- 283

Query: 123 RPGPSPPLQPRSRHPHTRYPRAVPEATPLR--------PPPGTRPRAKSRPGCRSSPFPA 174
                PP Q  S+   +R P   P+  P +        PPP  +P+     G      P 
Sbjct: 284 ---QGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 340

Query: 175 RSRTPGEAGPPRGDPRPRAPR-PGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQ 233
               P +  PP+G  + R+ R P   P+  P         PP P   N ++        Q
Sbjct: 341 PPGKP-QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAP-PAGQ 398

Query: 234 PQPPPPP 240
           PQ PP P
Sbjct: 399 PQGPPRP 405



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 35/124 (28%), Positives = 49/124 (39%), Gaps = 9/124 (7%)

Query: 121 RRRPGPSPPLQPRSRHPHT-RYPRAVPE--ATPLRPPP--GTRPRAKSRPGCRSSPFPAR 175
           + R   SPP +P+   P     P+  P     P  PPP  G +P+    PG    P P  
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG 166

Query: 176 SRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ 235
                 +  P G P+   P+ G+ P+  P     P   P  P  + G +  G     +PQ
Sbjct: 167 DNKSRSSRSPPGKPQGPPPQGGNQPQGPP----PPPGKPQGPPPQGGNKPQGPPPPGKPQ 222

Query: 236 PPPP 239
            PPP
Sbjct: 223 GPPP 226



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 50/209 (23%), Positives = 70/209 (33%), Gaps = 17/209 (8%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
           PPG  + P     N+   +R+ P                PPP    PP        +   
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP----PPGKPQGPPPQGGN 272

Query: 73  APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
            P   P        G P       GS+ R++ +     +   P G    + P P PP +P
Sbjct: 273 KPQGPPP------PGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP-PPPPGKP 325

Query: 133 RSRHPHT-RYPRAVPEATPLRPPPGTRPRAKSRP-GCRSSPFPARSRTPGEAGPPRGDPR 190
           +   P     P+  P   P   P G  P+  S+    RS P   +     E   P+G P 
Sbjct: 326 QGPPPQGGNKPQGPP---PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382

Query: 191 PRAPRPGDHPRRSPALRETPSLSPPSPGR 219
           P    P   P+  PA +      PP  GR
Sbjct: 383 PAGGNP-QQPQAPPAGQPQGPPRPPQGGR 410



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 44/189 (23%), Positives = 60/189 (31%), Gaps = 30/189 (15%)

Query: 4   EKATEEAAAPPGVAESPARPRVNEQWGSRAHPN-PRSASSAAAAASSSFPPPGFIHPPSS 62
           +  ++ A +PPG  + P     N+  G    P  P+             PPPG    P  
Sbjct: 229 DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP 288

Query: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTG----- 117
           +    SR   +P   P+  P      P       G          +  +   P G     
Sbjct: 289 QGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGP 348

Query: 118 --------RRWRRRPG-PSPPLQPRSRHP---------HTRYPRAVPEATPL---RPPPG 156
                   R  R  PG P  P Q    +P         + + P+A P   P    RPP G
Sbjct: 349 PPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQG 408

Query: 157 TRPRAKSRP 165
            RP   SRP
Sbjct: 409 GRP---SRP 414


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 58.5 bits (140), Expect = 8e-09
 Identities = 62/232 (26%), Positives = 86/232 (37%), Gaps = 22/232 (9%)

Query: 10   AAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSR 69
            +  PP     P  P       + A P P S   +A A S ++     + P + R +  + 
Sbjct: 1125 STTPPAATILPKGPPAP----ATATPAPTSPFPSATAGSMTY---SLVAPKAQRPSPKAP 1177

Query: 70   LRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPP 129
             +   A A   +    AGA  R G      L         +E  AP      +   P+PP
Sbjct: 1178 QKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPV----REPTAPESELEGQPTPPAPP 1233

Query: 130  LQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARS---RTPGEAGPPR 186
              P +  P  R       + PL PP   R  AK  P   +S FP+ S   R PG+    R
Sbjct: 1234 PLPETWTPTAR------SSPPLPPPAEERTSAKG-PETMASKFPSSSSDWRVPGQGLENR 1286

Query: 187  GDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPP 238
            G+P P  P P   P  +P      S    +      K AAG G   + +PPP
Sbjct: 1287 GEP-PTPPSPAPAPAVAPGGSSESSSGRAAGDTPERKEAAGTGKKVKVRPPP 1337



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 60/244 (24%), Positives = 83/244 (34%), Gaps = 47/244 (19%)

Query: 13   PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
            PP  A +P  P +   +      +P   SSA  A  S  PP          + V++   +
Sbjct: 1081 PPACA-APGGPVITAFYSG----SPAPTSSAPLAQPSQAPP----------SLVYTVATS 1125

Query: 73   APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
                A  +LP+    APA       S   +A A +      AP  +R      PSP    
Sbjct: 1126 TTPPAATILPKG-PPAPATATPAPTSPFPSATAGSMTYSLVAPKAQR------PSPKAPQ 1178

Query: 133  RSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPR 192
            + +      P    EA      PG  PR    PG    P    S   G+  PP   P P 
Sbjct: 1179 KVKAAIASIPVGSFEAGA-SGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPE 1237

Query: 193  APRPGDHPRRSPALRETPSLSPPSPGRRNGK----------------RAAGKGTTPQPQP 236
                      +P  R +P L PP+  R + K                R  G+G   + +P
Sbjct: 1238 T--------WTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEP 1289

Query: 237  PPPP 240
            P PP
Sbjct: 1290 PTPP 1293



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 30/105 (28%), Positives = 37/105 (35%), Gaps = 26/105 (24%)

Query: 139  TRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGD 198
            T  P       P+ PP GT           ++P P  S        P G P P +P    
Sbjct: 1525 TEQPPGAEAPLPVPPPTGT----------AAAPAPTPS--------PAGGPDPTSPSSD- 1565

Query: 199  HPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCAT 243
                S   +  P L PP     +G    G    PQP PPPP  +T
Sbjct: 1566 ----SGTAQAAPPLPPPP---ESGPGQPGWEGAPQPSPPPPGPST 1603



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 29/95 (30%), Positives = 35/95 (36%), Gaps = 12/95 (12%)

Query: 148  ATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALR 207
            ATP   PPG        P   ++  PA   TP  AG P  DP   +   G   + +P L 
Sbjct: 1522 ATPTEQPPGAEAPLPVPPPTGTAAAPAP--TPSPAGGP--DPTSPSSDSGT-AQAAPPLP 1576

Query: 208  ETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCA 242
              P   P  PG     +       P P PP P  A
Sbjct: 1577 PPPESGPGQPGWEGAPQ-------PSPPPPGPSTA 1604



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 31/113 (27%), Positives = 42/113 (37%), Gaps = 16/113 (14%)

Query: 122 RRPGPSPPLQPRSRHP-------HTRYPRAVPEATPLRPPPGTRPRAKSRPG-------C 167
           ++P   P    +S+ P       H R P     A P RPP  T P +   PG        
Sbjct: 59  QQPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPG-PGPPHPLGVV 117

Query: 168 RSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRR 220
            S   P  + T  EA  P G+PR  +    DH     ++       P  PG+R
Sbjct: 118 ESGKGPPPT-TEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKR 169



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 22/71 (30%), Positives = 26/71 (36%), Gaps = 1/71 (1%)

Query: 59   PPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGR 118
            PP + A +        AAAP   P   AG P  T   + S    AA        + P   
Sbjct: 1528 PPGAEAPLPVPPPTGTAAAPAPTPSP-AGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP 1586

Query: 119  RWRRRPGPSPP 129
             W   P PSPP
Sbjct: 1587 GWEGAPQPSPP 1597


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 74/277 (26%), Positives = 96/277 (34%), Gaps = 61/277 (22%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSR---- 69
           PG    P  P+ N        P PR       +   S PPP    P   +++ H+R    
Sbjct: 155 PGHRSGPPEPQRNRM------PPPRPD---VGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205

Query: 70  -----LRAAPAAAPRLLP----RVLAGAPARTGALAGSR-------LRAAAAAAHDQEAA 113
                 + +P   P   P      L G   R   L+ S        L    + A D +  
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 114 AP---TGRR---WRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPP---GTRPRAKSR 164
            P    G R    R    P PP   +   P T  P A  +A P  PPP   G  P   S 
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 165 PGCRSSP-FPARSRTPGEAGPPRGDPR---PRAPRPGDHPRRSPALRETPS----LSPPS 216
            G   +P  P R+ +   + PP   P    P  P P + P   P +R+ P     L PP 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP--PPPVRDPPGRSGPLPPPP 383

Query: 217 PGRRNGKRAAGKGTTPQ-------------PQPPPPP 240
           P  RNG  +     TPQ             P+PP PP
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 62/212 (29%), Positives = 73/212 (34%), Gaps = 41/212 (19%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
           PP V   P+  R         +  P   S+   +ASS  PPP    PP SR         
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP---PPPSRPG------- 317

Query: 73  APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
                P  LP      P+ +G     RL     +        P+  R     GP PP   
Sbjct: 318 -----PPPLP------PSSSGNDETPRLPQRNLSLSSSTPPLPSPGR----SGPLPPPPS 362

Query: 133 RSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG--PPRGDPR 190
               P  R P     + PL PPP       SR G  S   PA  + P  +G   PR  PR
Sbjct: 363 ERPPPPVRDPPG--RSGPLPPPPPV-----SRNGSTSRALPATPQLPSRSGVDSPRSGPR 415

Query: 191 PRAPRPGDHPRRSPALRETPSLSPPSPGRRNG 222
           P  P P D P         P   PPS   RNG
Sbjct: 416 P--PLPPDRPSAG-----APPPPPPSTSIRNG 440



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 42/126 (33%), Positives = 46/126 (36%), Gaps = 17/126 (13%)

Query: 124 PGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG 183
           P PS P +P    PH R    VP   P +P PG  P           PFP    T    G
Sbjct: 186 PVPSTP-RPIQSSPHNRGSPPVPGG-PRQPSPGPTP----------PPFPGNRGTALGGG 233

Query: 184 PPRGDP----RPRAPRPGDHPRRSPALRETPSLSPPSPGRRNG-KRAAGKGTTPQPQPPP 238
             R  P     P + RP   P  S AL + P   PP  G R    R A     PQ   PP
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293

Query: 239 PPCATR 244
            P   R
Sbjct: 294 VPSTPR 299



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 53/199 (26%), Positives = 68/199 (34%), Gaps = 30/199 (15%)

Query: 87  GAPARTGAL--AGS-RLRAAAAAAHDQEAAAPT-----GRRWRRRPGPSPPLQPRSRHPH 138
           G P   G L  AG  +LR+ A   +D   + P      GR    +P   P    R   P 
Sbjct: 95  GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154

Query: 139 TRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGD 198
             +    PE    R PP        RP   S P       P    P +  P  R   P  
Sbjct: 155 PGHRSGPPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP 207

Query: 199 HPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQP----------QPPPPPCATRREED 248
              R P+   TP   PP PG R    A G G+  Q           +PP PP  +R  +D
Sbjct: 208 GGPRQPSPGPTP---PPFPGNRG--TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262

Query: 249 MALRTRDRTSSRGTVFRAA 267
                     +R ++ R A
Sbjct: 263 KPPPPPPPVGNRPSIHREA 281


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 74/277 (26%), Positives = 96/277 (34%), Gaps = 61/277 (22%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSR---- 69
           PG    P  P+ N        P PR       +   S PPP    P   +++ H+R    
Sbjct: 155 PGHRSGPPEPQRNRM------PPPRPD---VGSKPDSIPPPVPSTPRPIQSSPHNRGSPP 205

Query: 70  -----LRAAPAAAPRLLP----RVLAGAPARTGALAGSR-------LRAAAAAAHDQEAA 113
                 + +P   P   P      L G   R   L+ S        L    + A D +  
Sbjct: 206 VPGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPP 265

Query: 114 AP---TGRR---WRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPP---GTRPRAKSR 164
            P    G R    R    P PP   +   P T  P A  +A P  PPP   G  P   S 
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 165 PGCRSSP-FPARSRTPGEAGPPRGDPR---PRAPRPGDHPRRSPALRETPS----LSPPS 216
            G   +P  P R+ +   + PP   P    P  P P + P   P +R+ P     L PP 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERP--PPPVRDPPGRSGPLPPPP 383

Query: 217 PGRRNGKRAAGKGTTPQ-------------PQPPPPP 240
           P  RNG  +     TPQ             P+PP PP
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPP 420



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 62/212 (29%), Positives = 73/212 (34%), Gaps = 41/212 (19%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
           PP V   P+  R         +  P   S+   +ASS  PPP    PP SR         
Sbjct: 268 PPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPP---PPPSRPG------- 317

Query: 73  APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
                P  LP      P+ +G     RL     +        P+  R     GP PP   
Sbjct: 318 -----PPPLP------PSSSGNDETPRLPQRNLSLSSSTPPLPSPGR----SGPLPPPPS 362

Query: 133 RSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG--PPRGDPR 190
               P  R P     + PL PPP       SR G  S   PA  + P  +G   PR  PR
Sbjct: 363 ERPPPPVRDPPG--RSGPLPPPPPV-----SRNGSTSRALPATPQLPSRSGVDSPRSGPR 415

Query: 191 PRAPRPGDHPRRSPALRETPSLSPPSPGRRNG 222
           P  P P D P         P   PPS   RNG
Sbjct: 416 P--PLPPDRPSAG-----APPPPPPSTSIRNG 440



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 42/126 (33%), Positives = 46/126 (36%), Gaps = 17/126 (13%)

Query: 124 PGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG 183
           P PS P +P    PH R    VP   P +P PG  P           PFP    T    G
Sbjct: 186 PVPSTP-RPIQSSPHNRGSPPVPGG-PRQPSPGPTP----------PPFPGNRGTALGGG 233

Query: 184 PPRGDP----RPRAPRPGDHPRRSPALRETPSLSPPSPGRRNG-KRAAGKGTTPQPQPPP 238
             R  P     P + RP   P  S AL + P   PP  G R    R A     PQ   PP
Sbjct: 234 SIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPP 293

Query: 239 PPCATR 244
            P   R
Sbjct: 294 VPSTPR 299



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 53/199 (26%), Positives = 68/199 (34%), Gaps = 30/199 (15%)

Query: 87  GAPARTGAL--AGS-RLRAAAAAAHDQEAAAPT-----GRRWRRRPGPSPPLQPRSRHPH 138
           G P   G L  AG  +LR+ A   +D   + P      GR    +P   P    R   P 
Sbjct: 95  GGPPGLGGLFQAGMPKLRSTANRDNDSGGSRPPLLPPGGRSTSAKPFSPPSGPGRFPVPS 154

Query: 139 TRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGD 198
             +    PE    R PP        RP   S P       P    P +  P  R   P  
Sbjct: 155 PGHRSGPPEPQRNRMPP-------PRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVP 207

Query: 199 HPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQP----------QPPPPPCATRREED 248
              R P+   TP   PP PG R    A G G+  Q           +PP PP  +R  +D
Sbjct: 208 GGPRQPSPGPTP---PPFPGNRG--TALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDD 262

Query: 249 MALRTRDRTSSRGTVFRAA 267
                     +R ++ R A
Sbjct: 263 KPPPPPPPVGNRPSIHREA 281


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 61/236 (25%), Positives = 93/236 (39%), Gaps = 21/236 (8%)

Query: 3    REKATEEAAAPPGVAESPARPRVNEQW--GSRAHPNPRSASSAAAAASSSFPPPGFIHPP 60
            R+    EA      + +PA P+  +     S  +  P  ASSA   AS S    G     
Sbjct: 3672 RDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDS--KKGSRQAH 3729

Query: 61   SSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRW 120
            S  AA+ S+  A P A P+L  R  A  P ++ + +  ++ + AA+   Q      G   
Sbjct: 3730 SGPAALQSK--AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGL-- 3785

Query: 121  RRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPG 180
                G  PP Q  ++    R  +     T    P  ++P  K +PG      P+ +  P 
Sbjct: 3786 ----GLQPPQQALTQ---ARLQQQSQPTTRGSAPAASQPAGKPQPG------PSTATGPQ 3832

Query: 181  EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQP 236
             AGPPR +    +      P++  A +  P+  P   G + G R  G    P  QP
Sbjct: 3833 PAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888



 Score = 44.3 bits (103), Expect = 2e-04
 Identities = 79/333 (23%), Positives = 113/333 (33%), Gaps = 41/333 (12%)

Query: 3   REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
           R+  T  A + PG A++ A P V      R  P P   +  + A      PP    P  S
Sbjct: 277 RQAETARATSVPGPAQAAAPPEVG-----RVSPQPPQPTKPSTAEPR---PPAGEAPAKS 328

Query: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
             AV + L A          +   G   +   L  S L  A+     Q  A   G+    
Sbjct: 329 ATAVPAGLGATE--------QTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPS 380

Query: 123 RPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFP---ARSRTP 179
           +  P       S+        A P+     P PG  P AK+ PG R  P     A  +T 
Sbjct: 381 KGTPKIVFNDASKE-------AGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTG 433

Query: 180 GEAGPPRGDPRPR-----APRPGDHPRR---SPALRETPSLSPPSPGRRNGKRAAGKGTT 231
           G   P  G    +     A +P   P+     P  +   ++   SP   N          
Sbjct: 434 GTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVC 493

Query: 232 PQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSH 291
                 P P    + E + L  + +    G++          S+Q   G     S T   
Sbjct: 494 NLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT--- 550

Query: 292 KPASLRRSGTQAWG-PRG-LPLRATPESFKGSP 322
             + L++ G Q  G P G LP +A+P S K SP
Sbjct: 551 --SPLKQKGPQGLGQPSGPLPAKASPLSTKASP 581



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 70/269 (26%), Positives = 96/269 (35%), Gaps = 39/269 (14%)

Query: 8    EEAAAPPGVAESPARPR-VNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHP------- 59
            +E   P  +  SPA P   +++ G      P + ++ A A   +  P G++ P       
Sbjct: 1348 KETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSE 1407

Query: 60   --PSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPT- 116
              PS  +  HS   +   A        L  AP+   A AG   R    +A D E   P  
Sbjct: 1408 RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAA-AGRAAREKPLSASDGEGGTPQP 1466

Query: 117  GRRWRRRPGPSPPLQPRSRH------PHTRYPRAVPE---ATPLRPPPGTRPRAKSRPGC 167
             R +      SPPL P S        P    PRA  E    TP   P    PR+   P  
Sbjct: 1467 SRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAP-- 1524

Query: 168  RSSPFPAR-SRTPGEAGPPR---GDPRPRAP-----RPGDHPRRSPALRETPSLSP-PSP 217
              SP  A+ ++TP     PR    +    AP        D   ++  +  + S SP  SP
Sbjct: 1525 TPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSP 1584

Query: 218  GRRNGKRAAGKGTTP------QPQPPPPP 240
                        TTP       P+PP PP
Sbjct: 1585 TETQPTTHGYSQTTPPSVSQLPPEPPGPP 1613



 Score = 37.0 bits (84), Expect = 0.026
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 13/111 (11%)

Query: 127 SPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCR--SSPFPARSRTPGEAGP 184
           SP L P   H   + P   P+    R P G +P ++     R  S P PA++  P E G 
Sbjct: 244 SPALSPA--HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVG- 300

Query: 185 PRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ 235
            R  P+P  P         P   E P+ S  +         AG G T Q Q
Sbjct: 301 -RVSPQPPQPTKPSTAEPRPPAGEAPAKSATAV-------PAGLGATEQTQ 343



 Score = 36.6 bits (83), Expect = 0.035
 Identities = 39/132 (29%), Positives = 49/132 (37%), Gaps = 22/132 (16%)

Query: 157 TRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPR------PRAPRPGDHPRRSPALRETP 210
           T PR+KS+    S   PA S     A  P G P       P  P+PG   R++   R T 
Sbjct: 232 TAPRSKSQQQLHS---PALSPAHSPAKQPLGKPDQERSRGPGGPQPGS--RQAETARAT- 285

Query: 211 SLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWG 270
             S P P +       G+ +   PQP  P  A  R        +  T        A   G
Sbjct: 286 --SVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSAT--------AVPAG 335

Query: 271 FGRSEQHLRGLT 282
            G +EQ   GLT
Sbjct: 336 LGATEQTQEGLT 347



 Score = 34.7 bits (78), Expect = 0.13
 Identities = 47/215 (21%), Positives = 73/215 (33%), Gaps = 34/215 (15%)

Query: 7    TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAV 66
            +E + +P   A S         +GS+    P++ S  AAA  ++   P            
Sbjct: 1406 SERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQ 1465

Query: 67   HSRLRA-APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPG 125
             SR  +   +++P L P   + +P  +    G R  A  +      A A    R    P 
Sbjct: 1466 PSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPT 1525

Query: 126  PSPPLQPRSRHPH------------------------------TRYPRAVPEATPLRPPP 155
            PSP +   ++ PH                              TR   A    +PL  P 
Sbjct: 1526 PSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPT 1585

Query: 156  GTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPR 190
             T+P   +  G   +  P+ S+ P E   P G PR
Sbjct: 1586 ETQP---TTHGYSQTTPPSVSQLPPEPPGPPGFPR 1617



 Score = 32.3 bits (72), Expect = 0.65
 Identities = 38/164 (23%), Positives = 60/164 (36%), Gaps = 43/164 (26%)

Query: 124 PGPSPPLQPRSRHPHTRYPRAVPEATPLRP--------PPGTRPRAKSRPGCRSSPFPAR 175
           P P PP  P S+ P    P      +PL+         P G  P   S    ++SP P++
Sbjct: 528 PTPLPP--PTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK 585

Query: 176 -------------SRTPGEAG------PPRGDPRPRAPRPGDHPRRSPALRETPSLSPPS 216
                        S+TP          P + +P P+ P     P  +P        +P +
Sbjct: 586 ASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPP-----PETTP--------TPAT 632

Query: 217 PGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSR 260
           P  ++G R A +  TP  +  P        ED+  +   + +SR
Sbjct: 633 PKVKSGVRRA-EPATPVVKAVPEAPKGGEAEDLVGKPYSQDASR 675



 Score = 32.0 bits (71), Expect = 0.85
 Identities = 26/83 (31%), Positives = 30/83 (36%), Gaps = 5/83 (6%)

Query: 166 GCRSSPFPARSRTPGEA---GPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNG 222
           G    P P     PG     GP  G P P AP  G     + A R T     P PG   G
Sbjct: 10  GAGDGPLPPGGAGPGPGPGPGPGAGKP-PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPG 68

Query: 223 KRAAGKGTTPQPQPPPPPCATRR 245
               G G+T +   P  P   +R
Sbjct: 69  P-GPGPGSTSRRLDPKEPLGNQR 90



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 37/140 (26%), Positives = 45/140 (32%), Gaps = 20/140 (14%)

Query: 124 PGPS---PPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRS----------- 169
           PGP    PP  P           A   A P  P PG  P     PG  S           
Sbjct: 29  PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGN 88

Query: 170 ----SPFP--ARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGK 223
               SP P  A + TPG   P     +  A +  D PRR+  +      S  SP     +
Sbjct: 89  QRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDR 148

Query: 224 RAAGKGTTPQPQPPPPPCAT 243
            +        PQ  P P +T
Sbjct: 149 GSTPTSPYSVPQIAPLPSST 168



 Score = 31.6 bits (70), Expect = 1.1
 Identities = 27/91 (29%), Positives = 38/91 (41%), Gaps = 9/91 (9%)

Query: 153  PPPGTRPRAKSRPGCRSSPF---PARSRTPGEAGPPRGDPRPRAPRPGDHPRRSP-ALRE 208
            P P   P A S P      +   PA ++ PG  GP R +    A R    P  +P A++E
Sbjct: 2262 PAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKE 2321

Query: 209  TPSLSPPSP--GRRNGKRAA---GKGTTPQP 234
                  P+P  G++    AA   G G   +P
Sbjct: 2322 AAGAPAPAPLAGQKPPADAAPGGGSGALSRP 2352



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 25/89 (28%), Positives = 34/89 (38%), Gaps = 3/89 (3%)

Query: 99  RLRAAAAAAHDQEAAAPTGRRWRRRP-GPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGT 157
           +L + A +     A  P G+  + R  GP  P QP SR   T    +VP       PP  
Sbjct: 241 QLHSPALSPAHSPAKQPLGKPDQERSRGPGGP-QPGSRQAETARATSVPGPAQAAAPPEV 299

Query: 158 RPRAKSRPGCRSSPFPARSRTPGEAGPPR 186
             R   +P   + P  A  R P    P +
Sbjct: 300 -GRVSPQPPQPTKPSTAEPRPPAGEAPAK 327


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 73/269 (27%), Positives = 103/269 (38%), Gaps = 59/269 (21%)

Query: 3   REKATEEAAAPPGVAESPARP---RVNEQWGSRAHPNPRSASSAAAAASSSFPPP----G 55
           R + +   A PP    +P  P   R       R  P+PR  S       S  PPP     
Sbjct: 556 RRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTA 615

Query: 56  FIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAP 115
              PP  R       RA+P+  P+   RV    P +  +   ++ R+ + ++  ++ ++P
Sbjct: 616 SPPPPPKR-------RASPSPPPKR--RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSP 666

Query: 116 TGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPAR 175
           + R  R    P    QP  RH  +  PRA   ++    PP  R  A S P  R SP P+ 
Sbjct: 667 S-RSTREARSP----QPNKRHSPSPRPRAPQTSSS---PPPVRRGASSSPQRRQSPSPST 718

Query: 176 ------SRTPG-----EAGPPR--------------GDPRPRAPRPGDHPRRSPALRETP 210
                 SRTP      +A  P               G P P A +P   P  SP   ++P
Sbjct: 719 RPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPP--SPVQSQSP 776

Query: 211 SL--SPPSPGRRNGKRAAGKGTTPQPQPP 237
           S   SP  P ++       K  TP P PP
Sbjct: 777 STNWSPAVPVKK------AKSPTPSPSPP 799



 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 67/245 (27%), Positives = 85/245 (34%), Gaps = 20/245 (8%)

Query: 3   REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAA--------AASSSFPPP 54
           R + +  A  PP    SP   + N    SR   +P   S             + S  P P
Sbjct: 398 RHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP 457

Query: 55  GFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAA 114
             +    S      ++ AA +   R   R      +     + S        +H +    
Sbjct: 458 RKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN--G 515

Query: 115 PTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPA 174
             GRR R  P  S    PR R   T  PR     +P  PPP  R R+ S      +P P 
Sbjct: 516 EVGRRRRHSPSRSASPSPRKRQKETS-PRGRRRRSP-SPPPTRRRRSPS-----PAPPPR 568

Query: 175 RSRTPGEAGPPRGDPRPRAPRPGDHPRR-SPALRETPSLSPPSPGRRNGKRAAGKGTTPQ 233
           R RTP    P R  P P   R    PRR SP ++   S SPP P RR             
Sbjct: 569 RRRTP-TPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP-PKRRTASPPPPPKRRAS 626

Query: 234 PQPPP 238
           P PPP
Sbjct: 627 PSPPP 631



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 62/258 (24%), Positives = 87/258 (33%), Gaps = 31/258 (12%)

Query: 7   TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAV 66
           T+  +  P   +    P + E       P+ + A+S +       P P  I  P   +  
Sbjct: 205 TKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEP--IPEPKEPSPE 262

Query: 67  HSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGP 126
            +  +       R   R  + + +RT + + S  R          + +P     RRRP P
Sbjct: 263 KNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSP-----RRRPSP 317

Query: 127 SPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPR 186
                PR R P  R P          P    R  + S  G  SS   +RSR+P +  P R
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377

Query: 187 GDPRPRAPR---PGDHPRRSPALRETPSLSPP---------------------SPGRRNG 222
               PR  R   P   P R       P+  PP                     SPGR +G
Sbjct: 378 TSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSG 437

Query: 223 KRAAGKGTTPQPQPPPPP 240
           K    KGT  +  P P P
Sbjct: 438 KVTKHKGTEKRESPSPAP 455



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 72/287 (25%), Positives = 107/287 (37%), Gaps = 41/287 (14%)

Query: 36  NPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGAL 95
           N +S+S + +++SS    P   H  +       R   + +A+P    R    +P      
Sbjct: 489 NQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPR----- 543

Query: 96  AGSRLRAAA---AAAHDQEAAAPTGRRWR------RRPGPSPPLQPRSRHPHTRYPRAVP 146
            G R R+ +          + AP  RR R      RR  PSPP + RS  P    P    
Sbjct: 544 -GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQR 602

Query: 147 EATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRP----RAP------RP 196
             +P  PP          P  R+SP P   R    + PP+    P    R+P      R 
Sbjct: 603 RYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK 662

Query: 197 GDHPRRS--------PALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREED 248
           G  P RS        P  R +PS  P +P   +      +G +  PQ    P  + R   
Sbjct: 663 GSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTR--- 719

Query: 249 MALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLIISCTLSHKPAS 295
             +R   RT     + +AA      S Q +R ++   S + S +PA+
Sbjct: 720 -PIRRVSRTPEPKKIKKAA----SPSPQSVRRVSSSRSVSGSPEPAA 761



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 54/219 (24%), Positives = 82/219 (37%), Gaps = 26/219 (11%)

Query: 5   KATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPP---PGFIHPPS 61
           K  +    P     SP +    E+   +  P  RS S + +   S  P    P   H   
Sbjct: 246 KVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR 305

Query: 62  SRAAVHSRL---RAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGR 118
           SR+    R    R  P+   R  PR +   P    + +  R R  ++A+    +++ +  
Sbjct: 306 SRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSS 365

Query: 119 RWRRRPGPSPPLQP--RSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARS 176
           R R     SPP +P  R+  P  +  R  P A+P R      P A   P  R SP P +S
Sbjct: 366 RSR-----SPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQS 420

Query: 177 -------------RTPGEAGPPRGDPRPRAPRPGDHPRR 202
                        RT G+    +G  +  +P P   PR+
Sbjct: 421 NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRK 459



 Score = 45.1 bits (105), Expect = 1e-04
 Identities = 42/139 (30%), Positives = 54/139 (38%), Gaps = 28/139 (20%)

Query: 124 PGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG 183
           P P P  +P+   P     +        +    TRPR++SR   RS     RSR+P    
Sbjct: 248 PKPEPIPEPKEPSPEKNSKKE-------KEKEKTRPRSRSRSKSRSR---TRSRSPSHTR 297

Query: 184 PPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCAT 243
           P R   R R+      PRR P+ R  PS     P RR          TP  + PPPP   
Sbjct: 298 PRR---RHRSRSRSYSPRRRPSPRRRPS-----PRRR----------TPPRRMPPPPRHR 339

Query: 244 RREEDMALRTRDRTSSRGT 262
           R    +  R R   S  G+
Sbjct: 340 RSRSPVRRRRRSSASLSGS 358



 Score = 37.7 bits (86), Expect = 0.015
 Identities = 43/160 (26%), Positives = 64/160 (40%), Gaps = 27/160 (16%)

Query: 160 RAKSR---PGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPR-RSPALRETPSLSPP 215
           R KSR   P  RSSP   R R    +  PR   + R+P P    + ++P L E PS+   
Sbjct: 174 RRKSRSPSPRRRSSPV-RRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPE-PSVKVK 231

Query: 216 SPGRRNGKRAAGKGTTPQPQP-----PPPPCATRREEDMALRTRDRTSSRGTVFRAADWG 270
            P  +     +     P+P+P      P P    ++E    +TR R+ SR    ++    
Sbjct: 232 EPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRS---KSRSRT 288

Query: 271 FGRSEQHLRGLTLIISCTLSHKPASLRRSGTQAWGPRGLP 310
             RS  H R             P    RS ++++ PR  P
Sbjct: 289 RSRSPSHTR-------------PRRRHRSRSRSYSPRRRP 315



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 44/161 (27%), Positives = 67/161 (41%), Gaps = 28/161 (17%)

Query: 5   KATEEAAAP-PGVAESPA-RPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
           ++T EA +P P    SP+ RPR   Q  S   P  R ASS+     S  P    I   S 
Sbjct: 668 RSTREARSPQPNKRHSPSPRPRA-PQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVS- 725

Query: 63  RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
           R     +++ A + +P+ + RV     + + +++GS   AA                  +
Sbjct: 726 RTPEPKKIKKAASPSPQSVRRV-----SSSRSVSGSPEPAA------------------K 762

Query: 123 RPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKS 163
           +P P+PP   +S+ P T +  AVP      P P   P   S
Sbjct: 763 KP-PAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNS 802


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 67/206 (32%), Positives = 77/206 (37%), Gaps = 27/206 (13%)

Query: 82  PRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRY 141
           PR LAG      A A     A +  A ++ AA    + WRR  G      P S  P  R 
Sbjct: 7   PRRLAGLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS--PLYRV 64

Query: 142 PRAVPEATPLRPPPG-----TRPRAKSRPGCRSSPFPARSRT-----PGEAGPPRGDPRP 191
             A P A P  PPPG      RPRA  RPG   SP P   R       G AG  R     
Sbjct: 65  -SAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAA 123

Query: 192 RAPRPGDHPRRS---PALR--ETPSLSPP--SPGRRNGKRAAGKG------TTPQPQPPP 238
            +      P R+   PALR       SPP  SPG R G  A G+         P    PP
Sbjct: 124 LSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGRPGSEARGRSGAECARRVPLHHGPP 183

Query: 239 PPCATRREEDMALRTRDRTSSRGTVF 264
                  E D   +   +T +RG  F
Sbjct: 184 GASGVGSERDRKFQLH-QTPARGPPF 208



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 65/196 (33%), Positives = 76/196 (38%), Gaps = 33/196 (16%)

Query: 30  GSRAHPNPRSASSAAAAASS----SFPPPGFIHPPSSRAAVHS-RLRAAPAAAPRLLPRV 84
           GS+    PR A SA A  S     S PPP    PP       S R RA       + P  
Sbjct: 41  GSKLWRRPRGAVSAGAPGSPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGP 100

Query: 85  LAGAPARTGALAGS--RLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYP 142
           L G  A     AGS  RLR +AAA    +   P       R    P L+  S  P     
Sbjct: 101 L-GRRASCSGRAGSAGRLRCSAAALSAAQRGGPA------RAQVPPALRTFSPGP----- 148

Query: 143 RAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRR 202
                A+P R  PG RP +++R   RS    AR R P   GPP       A   G    R
Sbjct: 149 -----ASPPRASPGGRPGSEARG--RSGAECAR-RVPLHHGPPG------ASGVGSERDR 194

Query: 203 SPALRETPSLSPPSPG 218
              L +TP+  PP PG
Sbjct: 195 KFQLHQTPARGPPFPG 210



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 58/203 (28%), Positives = 71/203 (34%), Gaps = 41/203 (20%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNP--RSASSAAAAAS------SSFPPPGFIHPPSSRA 64
           PPG      RPR   + G+   P P  R AS +  A S      S+           +RA
Sbjct: 76  PPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARA 135

Query: 65  AVHSRLRA---APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWR 121
            V   LR     PA+ PR  P    G+ AR    +G+         H    A+  G    
Sbjct: 136 QVPPALRTFSPGPASPPRASPGGRPGSEAR--GRSGAECARRVPLHHGPPGASGVGSERD 193

Query: 122 RR------PGPSPPLQPRSRHPHTRYPRAVPEAT-PLRPPPGTRPRAKSRPGCRSSPFPA 174
           R+      P   PP    S    TR P  +       R PPG  P               
Sbjct: 194 RKFQLHQTPARGPPFPGIS--GMTRGPVVLSGVNRQHRWPPGASP--------------- 236

Query: 175 RSRTPGEAG---PPRGDPRPRAP 194
            SR+ GEAG   P R   RPRAP
Sbjct: 237 -SRSLGEAGGERPARALRRPRAP 258


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 57.0 bits (136), Expect = 2e-08
 Identities = 67/206 (32%), Positives = 77/206 (37%), Gaps = 27/206 (13%)

Query: 82  PRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRY 141
           PR LAG      A A     A +  A ++ AA    + WRR  G      P S  P  R 
Sbjct: 7   PRRLAGLQRTPAAYANEAALAISGRADEEGAAGAGSKLWRRPRGAVSAGAPGS--PLYRV 64

Query: 142 PRAVPEATPLRPPPG-----TRPRAKSRPGCRSSPFPARSRT-----PGEAGPPRGDPRP 191
             A P A P  PPPG      RPRA  RPG   SP P   R       G AG  R     
Sbjct: 65  -SAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAA 123

Query: 192 RAPRPGDHPRRS---PALR--ETPSLSPP--SPGRRNGKRAAGKG------TTPQPQPPP 238
            +      P R+   PALR       SPP  SPG R G  A G+         P    PP
Sbjct: 124 LSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGRPGSEARGRSGAECARRVPLHHGPP 183

Query: 239 PPCATRREEDMALRTRDRTSSRGTVF 264
                  E D   +   +T +RG  F
Sbjct: 184 GASGVGSERDRKFQLH-QTPARGPPF 208



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 65/196 (33%), Positives = 76/196 (38%), Gaps = 33/196 (16%)

Query: 30  GSRAHPNPRSASSAAAAASS----SFPPPGFIHPPSSRAAVHS-RLRAAPAAAPRLLPRV 84
           GS+    PR A SA A  S     S PPP    PP       S R RA       + P  
Sbjct: 41  GSKLWRRPRGAVSAGAPGSPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGP 100

Query: 85  LAGAPARTGALAGS--RLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYP 142
           L G  A     AGS  RLR +AAA    +   P       R    P L+  S  P     
Sbjct: 101 L-GRRASCSGRAGSAGRLRCSAAALSAAQRGGPA------RAQVPPALRTFSPGP----- 148

Query: 143 RAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRR 202
                A+P R  PG RP +++R   RS    AR R P   GPP       A   G    R
Sbjct: 149 -----ASPPRASPGGRPGSEARG--RSGAECAR-RVPLHHGPPG------ASGVGSERDR 194

Query: 203 SPALRETPSLSPPSPG 218
              L +TP+  PP PG
Sbjct: 195 KFQLHQTPARGPPFPG 210



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 58/203 (28%), Positives = 71/203 (34%), Gaps = 41/203 (20%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNP--RSASSAAAAAS------SSFPPPGFIHPPSSRA 64
           PPG      RPR   + G+   P P  R AS +  A S      S+           +RA
Sbjct: 76  PPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARA 135

Query: 65  AVHSRLRA---APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWR 121
            V   LR     PA+ PR  P    G+ AR    +G+         H    A+  G    
Sbjct: 136 QVPPALRTFSPGPASPPRASPGGRPGSEAR--GRSGAECARRVPLHHGPPGASGVGSERD 193

Query: 122 RR------PGPSPPLQPRSRHPHTRYPRAVPEAT-PLRPPPGTRPRAKSRPGCRSSPFPA 174
           R+      P   PP    S    TR P  +       R PPG  P               
Sbjct: 194 RKFQLHQTPARGPPFPGIS--GMTRGPVVLSGVNRQHRWPPGASP--------------- 236

Query: 175 RSRTPGEAG---PPRGDPRPRAP 194
            SR+ GEAG   P R   RPRAP
Sbjct: 237 -SRSLGEAGGERPARALRRPRAP 258


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 63/242 (26%), Positives = 85/242 (35%), Gaps = 33/242 (13%)

Query: 12   APPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLR 71
            AP   A +P  P+     G  A P+P+ A +  AA   S P  G   PP   A       
Sbjct: 1217 APTTPAATPPSPK-----GGLATPSPKGAPTTPAATPPS-PKGGPATPPPKGAPT----- 1265

Query: 72   AAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQ 131
              PAA P  L   LA  P +     G+   A       +   A +  +    P  + P  
Sbjct: 1266 -PPAATPPSLKGGLATPPHK-----GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS 1319

Query: 132  PRSRHPHTRYPRAVPEATPLRPP--------PGTRPRAKSRPGCRSS---PFPARSRTPG 180
            P+   P T  P+  P    + PP        P T P +K  P   SS   P P  +    
Sbjct: 1320 PKGS-PGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH 1378

Query: 181  EAGPPRGDPRPRA----PRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQP 236
            + GP    P P+     P P   P     +  +P  +P +P  R G     KG    P  
Sbjct: 1379 KGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 237  PP 238
             P
Sbjct: 1439 TP 1440



 Score = 56.2 bits (134), Expect = 4e-08
 Identities = 73/252 (28%), Positives = 97/252 (38%), Gaps = 44/252 (17%)

Query: 12   APPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLR 71
            AP   A +P  P+     G  A P P+ A +  AA   S  P G +  PS + A      
Sbjct: 1148 APTTPAATPPSPK-----GGLATPPPKGAPTTPAATPPS--PKGGLATPSPKGA-----P 1195

Query: 72   AAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQ 131
              PAA P   P+     P+  GA       AA   +     A P+ +     P  +PP  
Sbjct: 1196 TTPAATPP-SPKGGLATPSPKGA---PTTPAATPPSPKGGLATPSPKGAPTTPAATPP-S 1250

Query: 132  PRSRHPHTRYPRAVPEATPLRPPPGTRPRAK---SRPGCRSSPFPARSRTPGEAG----- 183
            P+   P T  P+  P      PP  T P  K   + P  + +P PA    P   G     
Sbjct: 1251 PKG-GPATPPPKGAP-----TPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATS 1304

Query: 184  PPRGDPRPRAPRPGDHPRRSP------ALRETPSLSPPSPG-----RRNGKRAAGKGTTP 232
            PP+G P P A  P   P+ SP           P+++PPSP            + G  TTP
Sbjct: 1305 PPKGAPTPPAATP-PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTP 1363

Query: 233  -QPQPPPPPCAT 243
               + P PP AT
Sbjct: 1364 SSKEGPTPPAAT 1375



 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 65/246 (26%), Positives = 84/246 (34%), Gaps = 24/246 (9%)

Query: 12   APPGVA----ESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVH 67
            +P GV     E+P    VN  +       P    + A + +SS P      P        
Sbjct: 874  SPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPAS 933

Query: 68   SRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPS 127
               + AP   P   P    G PA           AA   +     A P+ +     P  +
Sbjct: 934  PSPKGAPTP-PAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAAT 992

Query: 128  PPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRG 187
            PP  P+   P T  P+  P      PP  T P  K  P   ++PFP  + TP  A PP  
Sbjct: 993  PP-SPKGG-PATPSPKGAPT-----PPAVTPPSPKGSPA--ATPFPKGASTPPAATPPSP 1043

Query: 188  DPRPRA-PRPGDHPRRSPALRETPSLSP--------PSPGRRNGKRAAGKGTTPQPQ-PP 237
               P A P P   P    A   +P   P        P+P         G   TP P+  P
Sbjct: 1044 KGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103

Query: 238  PPPCAT 243
             PP AT
Sbjct: 1104 MPPAAT 1109



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 58/243 (23%), Positives = 83/243 (34%), Gaps = 12/243 (4%)

Query: 6    ATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAA 65
            AT  +  PP    +P  P        +    P   +   +  +  FP  G   P   +A 
Sbjct: 851  ATTHSPTPPSPKGAPT-PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909

Query: 66   VHSRLRAAPAAAPRL-LPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRP 124
              S   ++P  A     P+ +  +P+  GA        AA     +   A    +W   P
Sbjct: 910  ALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP----AATPPSPKGGPATPSPKWAPTP 965

Query: 125  GPSPPLQPRSRHPHTRYPRAVPEATPLRPP-PGTRPRAKSRPGCRSSPF---PARSRTPG 180
              + P  P+   P T  P+  P      PP P   P   S  G  + P    P+   +P 
Sbjct: 966  PAATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 181  EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240
                P+G   P A  P   P+ SPA    P  +P +P         G  T      P PP
Sbjct: 1025 ATPFPKGASTPPAATPPS-PKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPP 1083

Query: 241  CAT 243
             AT
Sbjct: 1084 AAT 1086



 Score = 52.8 bits (125), Expect = 5e-07
 Identities = 74/279 (26%), Positives = 99/279 (35%), Gaps = 64/279 (22%)

Query: 9    EAAAPPGVAESPARPRVNEQWGSRAHPNP-RSASSAAAAASSSFPPPG---FIHPPSSRA 64
            ++ +P GV+ SP   R   + GS     P  + SS  +   +SF P     F     S A
Sbjct: 792  DSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPA 851

Query: 65   AVHSRLRAAPAAAPR------LLPRVLAGAPART-------------------------- 92
              HS    +P  AP       L P+ +   P  T                          
Sbjct: 852  TTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPAL 911

Query: 93   GALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLR 152
               + S  +A A  A     A+P+ +     P  +PP  P+   P T  P+  P      
Sbjct: 912  SMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPP-SPKGG-PATPSPKWAPT----- 964

Query: 153  PPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSL 212
            PP  T P  K  P   ++P P  + TP  A PP     P  P P   P         P++
Sbjct: 965  PPAATPPSPKGGP---ATPSPKGAPTPPAATPPSPKGGPATPSPKGAP-------TPPAV 1014

Query: 213  SPPSPGRRNGKRAA-----GKGTTPQPQPPPP---PCAT 243
            +PPSP    G  AA     G  T P   PP P   P AT
Sbjct: 1015 TPPSP---KGSPAATPFPKGASTPPAATPPSPKGSPAAT 1050



 Score = 52.4 bits (124), Expect = 6e-07
 Identities = 62/248 (25%), Positives = 84/248 (33%), Gaps = 24/248 (9%)

Query: 8    EEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVH 67
            +E  A P   ++PA    +     +A   P      A+ +    P P    PPS +    
Sbjct: 897  KEGPATPAPKQAPALSMTSSS-PKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPA 955

Query: 68   SRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPS 127
            +         P   P    G PA           AA   +     A P+ +     P  +
Sbjct: 956  TPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT 1015

Query: 128  PPLQPRSRHPHTRYPRAV---PEATPLRPP--PGTRPRAKSRPGCRSSPFPARSRTPGEA 182
            PP  P+     T +P+     P ATP  P   P   P  K  P   ++  P  S   G A
Sbjct: 1016 PP-SPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLP--SPKGGPA 1072

Query: 183  GPP-RGDPRPRAPRPGDHPRRSPALRET------PSLSPPSPGRRNGKRAAGKGTTPQPQ 235
             P  +G P P A  P   P+  PA          P+ +PPSP         G  T P   
Sbjct: 1073 TPSLKGAPTPPAATPPS-PKGGPATPSPKGAPMPPAATPPSP-------KGGLATPPHKG 1124

Query: 236  PPPPPCAT 243
             P  P AT
Sbjct: 1125 APTTPAAT 1132



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 61/242 (25%), Positives = 79/242 (32%), Gaps = 34/242 (14%)

Query: 7    TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAV 66
            T  AA  P     PA P +       A   P      A  +    P P    PPS +  +
Sbjct: 1058 TTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGL 1117

Query: 67   ----HSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR 122
                H      PAA P          P+  G LA    + A        A  P+ +    
Sbjct: 1118 ATPPHKGAPTTPAATP----------PSPKGGLATPPPKGAPTT---PAATPPSPKGGLA 1164

Query: 123  RPGP-SPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGE 181
             P P   P  P +  P  +   A P        P   P   S  G  ++P P  + T   
Sbjct: 1165 TPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP--PSPKGGLATPSPKGAPTTPA 1222

Query: 182  AGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPC 241
            A P    P P+       P+ +P    TP+ +PPSP         G  T P    P PP 
Sbjct: 1223 ATP----PSPKGGLATPSPKGAPT---TPAATPPSP-------KGGPATPPPKGAPTPPA 1268

Query: 242  AT 243
            AT
Sbjct: 1269 AT 1270



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 62/247 (25%), Positives = 86/247 (34%), Gaps = 33/247 (13%)

Query: 7    TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSR-AA 65
            T  A  P  + ++PA         S     P + SS       +  PP    PP+ +  A
Sbjct: 1434 TPPAVTPVSLKKAPAT--------SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485

Query: 66   VHSRLRAAPAAAPRL----LPRVLAGAPARTGALAGSRLRAAAAAAH-----------DQ 110
              S  + APA    +    LP V+  +P    A   SR    A  A             +
Sbjct: 1486 TSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPK 1545

Query: 111  EAAAP---TGRRWRRRPG-PSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPG 166
            EA  P   T    ++ P  P+P   P +  P ++   + P  TP        P+    P 
Sbjct: 1546 EALIPPAMTVPSPKKTPAIPTPKEAPAT--PSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603

Query: 167  CRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAA 226
              +SP P  + TP    PP  +  P  P P   P   P    +   SP SP     K  A
Sbjct: 1604 AVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663

Query: 227  GKGTTPQ 233
               T PQ
Sbjct: 1664 ---TVPQ 1667



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 60/256 (23%), Positives = 82/256 (32%), Gaps = 23/256 (8%)

Query: 7    TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSR--- 63
            T  AA PP     PA P         A   P      A       P P  + PPS +   
Sbjct: 1242 TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGP 1301

Query: 64   AAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQ-EAAAPTGRRWRR 122
            A    +    P AA    P+   G P   GA     +   +        A  P+ +    
Sbjct: 1302 ATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361

Query: 123  RP----GPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRT 178
             P    GP+PP    S           P+  P  P P   P + +         PA   T
Sbjct: 1362 TPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVT 1421

Query: 179  -PGEAGPPRGDPRPRAPRP--------GDHPRRSPALRET------PSLSPPSPGRRNGK 223
              G A P +GD  P A  P           P+  PA   +      P+++PPSP      
Sbjct: 1422 REGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAP 1481

Query: 224  RAAGKGTTPQPQPPPP 239
            +     ++P+  P  P
Sbjct: 1482 KQVATSSSPKKAPATP 1497



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 55/248 (22%), Positives = 89/248 (35%), Gaps = 34/248 (13%)

Query: 3    REKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSS 62
            +E  T  A  PP   + PA P             P+   ++     SS         P+S
Sbjct: 1611 KEAPTPPAVTPPSPEKGPATPA------------PKGTPTSPPVTPSSLK-----DSPTS 1653

Query: 63   RAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPT--GRRW 120
             A+V  ++ A        +P+   G PA+ G  A   +  A A        APT  G + 
Sbjct: 1654 PASVTCKMGAT-------VPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQT 1706

Query: 121  RRRPGPSPPLQP-RSRHPHTRYPRAVPEATPLRP-PPGTRPRAKSRPGCRS-----SPFP 173
            ++    SPP+ P  S    ++ P +     PL P    +   AK +    S     +P  
Sbjct: 1707 KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPE 1766

Query: 174  ARSRTPGEAGP-PRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTP 232
            +++ TP  A    +  P+P +      P    +L   PS  P  P ++    ++      
Sbjct: 1767 SKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826

Query: 233  QPQPPPPP 240
             P  P  P
Sbjct: 1827 SPSKPLAP 1834



 Score = 33.9 bits (76), Expect = 0.22
 Identities = 47/171 (27%), Positives = 59/171 (34%), Gaps = 30/171 (17%)

Query: 35  PNPRSASSAAAAASSSFPPPGFIHP-------PSSRAAVHSRLRAAPAAAPRLLPRVLAG 87
           P P+    +AA  +S FP P  I         P S +     L  AP  AP  LP  L G
Sbjct: 51  PAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP-EAPTFLPN-LIG 108

Query: 88  APARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPE 147
            P    ALA +               APT    +  P  S PL   +  PH+    +   
Sbjct: 109 PPISPAALALA-----------SPMIAPT---LKGTPSSSAPLALVALAPHSVQKSSAFP 154

Query: 148 ATPLRPPPGTRPRAK------SRPGCRSSPFPARSRTPGEAGP-PRGDPRP 191
              L  PP             S P   S P    ++ P E  P P+G P P
Sbjct: 155 PNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSP 205


>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
          Length = 1015

 Score = 55.8 bits (133), Expect = 5e-08
 Identities = 81/281 (28%), Positives = 100/281 (35%), Gaps = 55/281 (19%)

Query: 2   CREKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPS 61
           C E A EE AAP       ARPR   +      P P+S   AA A     P P  +    
Sbjct: 188 CVEVALEEGAAP-------ARPRTVPKRQIELRPRPQSPPRAAGA-----PRPRLLLRTG 235

Query: 62  SRAAVHSRLRAAPAAAPRLLPRVLA-GAPARTGALAGS------RLRAAAAAAH------ 108
           S       L+AA       L R L+  APA + A  GS        R  A + H      
Sbjct: 236 SLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKA 295

Query: 109 --------DQEAAAPTGRRWR-------RRPGPSP---PLQPRSRHPHTRYPRAVPEAT- 149
                   D  A A   R W        RR  P+P   PL P S     +    + EA  
Sbjct: 296 KSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARK 355

Query: 150 ---PLRPPPGTRPRAKSRP-GCR-SSPFPARSRTPGEAGPPRGDPR-----PRAPRPGD- 198
              P   P  T  RA+S P  CR  S  P+R+  P    PPR  P      PR P P + 
Sbjct: 356 TRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNL 415

Query: 199 HPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPP 239
            P      R +  L P +      +  A + T  +  P PP
Sbjct: 416 SPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPP 456



 Score = 35.0 bits (79), Expect = 0.10
 Identities = 55/206 (26%), Positives = 71/206 (34%), Gaps = 30/206 (14%)

Query: 63  RAAVHSRLRA-APAAAPRLLP--RVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRR 119
           R  V SR+RA  P    R +   R++     RT  L G+R  +  +        +P    
Sbjct: 744 RPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGS 803

Query: 120 WRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPP--------GTRPRAKSRP---GCR 168
            + +  PSP + P+ + P T    A     PL   P          +PRA S P      
Sbjct: 804 PQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSP 863

Query: 169 SSPFPARSRTPGEA--GPPRGDPRPRAPRPGDHPRRSPALRE-------------TPSLS 213
            SP     R PG A  G    DP        + PR+ P LR               P  S
Sbjct: 864 QSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQ-PRLRVLFDPESGQYVEVLLPPSS 922

Query: 214 PPSPGRRNGKRAAGKGTTPQPQPPPP 239
           P  P R     A G G  P    P P
Sbjct: 923 PGPPHRVYTPLALGLGLYPPAYGPIP 948


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 55.5 bits (132), Expect = 7e-08
 Identities = 75/297 (25%), Positives = 105/297 (35%), Gaps = 47/297 (15%)

Query: 6   ATEEAAAPPGVA----ESPARPRVNEQWGSRAHPNPRSASSAAA---AASSSFPPPGFIH 58
           AT    APP +A    ++P  P  +      A P+P++ ++ A     A  S PP   + 
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ 674

Query: 59  PPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGR 118
            P S  A  S   +  A  P   P  LA  P +      +    + +A    +A  P   
Sbjct: 675 APFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 732

Query: 119 RWRRRPGPSPPLQPRSRHPHTRYPRAVP-----------------EATPLRPPPGTRPRA 161
              + P PSPP  P      T  PR  P                   +PL  PP   P A
Sbjct: 733 PPLQVP-PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791

Query: 162 KSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRN 221
            + P  ++ P P  S  PG+A        P +P     P+  P L       PPSP    
Sbjct: 792 LATPPLQALPSPPAS-FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASP 850

Query: 222 GKRAAGKGTTPQPQ---------------PPPP----PCATRREEDMALRTRDRTSS 259
             +A  +  TP P                PPPP    P +T    D+A  +   TS+
Sbjct: 851 TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 907



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 67/253 (26%), Positives = 83/253 (32%), Gaps = 41/253 (16%)

Query: 30  GSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAP 89
           G       RSA SA A   +S P PG    PS   A  SR        PR  P      P
Sbjct: 145 GKATEAPKRSALSAGARRDTSGPTPG---TPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201

Query: 90  ARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR------------------------RPG 125
                  G R   ++A+ H     +P  RR                           R G
Sbjct: 202 TE-----GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256

Query: 126 PSPPLQPRS-RHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGC---RSSPFPARSRTPGE 181
           PS    PR+  HP    P+ +     LRPP  T PR  + P      SSP    S +  +
Sbjct: 257 PSARGTPRAPAHPSQPKPKGLQA---LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 182 AGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAA-GKGTTPQPQPPPPP 240
           A P         P P   P   P     P L+PPSP      +       TP  Q PP  
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLP-LAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 241 CATRREEDMALRT 253
                +   +L+T
Sbjct: 373 TTPPMQAPPSLQT 385



 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 64/251 (25%), Positives = 84/251 (33%), Gaps = 66/251 (26%)

Query: 6   ATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAA 65
           AT    APP +A  P +   +      A P P++             PP    PP     
Sbjct: 588 ATPPPQAPPALASPPLQGLPSPPLSPLATPPPQA-------------PPXLALPPLQAPP 634

Query: 66  VHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPG 125
                  +P A+P L P +   +P    ALA   L+A  +                  P 
Sbjct: 635 -------SPPASPPLSP-LATPSPQAPNALAVHLLQAPFS------------------PP 668

Query: 126 PSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARS--RTPGEAG 183
           PSPP+Q     P +  P A P  +P   PP   P + + P  +  P P  S   +P    
Sbjct: 669 PSPPVQA----PFS--PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 722

Query: 184 PPRGDP----------------RPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAG 227
           PP+  P                 P +P     PR  P L   P   PPSP          
Sbjct: 723 PPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA 782

Query: 228 KGTTPQPQPPP 238
           K   P PQ PP
Sbjct: 783 K---PPPQAPP 790



 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 72/272 (26%), Positives = 96/272 (35%), Gaps = 66/272 (24%)

Query: 40  ASSAAAAASSSFPPPGFI--HPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPA------- 90
           A + AAA + +   PG +   PP S        R  P   P  L RVL  A A       
Sbjct: 8   AKAGAAARTPAARAPGLLTPRPPGSP-------RPPPPVTPAAL-RVLGAAGAVGRKPLA 59

Query: 91  -RTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRS-RHPHTRYPRAVPEA 148
            R G + G+ +  +A  A    +A  + R     P   PP   R  R P  +     P +
Sbjct: 60  ERAGGIGGATIPESAPRAGPTRSAGTSSRN----PASRPPASGRGERAPPAKNTSPGPVS 115

Query: 149 TPLRPPPGTRPRAKSRPGCRSS----------------------------------PFPA 174
           +P R    TRP    + G R S                                  P PA
Sbjct: 116 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175

Query: 175 ---RSRTPG-EAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGT 230
              RSR  G E G PR  P  R   P + PR+S +     S + PSP  R  + +AG G 
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGL 234

Query: 231 TPQPQPPPPPCATRREEDMALRTRDRTSSRGT 262
               Q P     +     ++   R   S+RGT
Sbjct: 235 ----QRPASRSLSSSATPLSSPARSGPSARGT 262



 Score = 39.7 bits (91), Expect = 0.004
 Identities = 64/279 (22%), Positives = 84/279 (30%), Gaps = 75/279 (26%)

Query: 11   AAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRL 70
            AAPP   + P  P  +      A P P++  + A     + P P    P  +  +  + L
Sbjct: 762  AAPP--LQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL 819

Query: 71   RAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPL 130
              +P A P          P     LA   L+   +       A+PT +  RR P P P  
Sbjct: 820  PMSPLATP---------PPQAPPVLAAPLLQVPPSPP-----ASPTLQAPRRPPTPGPDT 865

Query: 131  QPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPG---------CRSSPFPARSRTPGE 181
                       PR      P  PPP +R  + +  G           S+P   R    G 
Sbjct: 866  SVSG-------PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 918

Query: 182  AGPPRGDPRPRAPRPGDHPR---RSPA------------LRETPSLSP------------ 214
             G     P P A     HP    R PA            L   P+  P            
Sbjct: 919  EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET 978

Query: 215  ----------------PSPGRRNGKRAAGKGTTPQPQPP 237
                            PSPG   GK AAG G     + P
Sbjct: 979  EGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 1017



 Score = 35.8 bits (81), Expect = 0.059
 Identities = 62/239 (25%), Positives = 83/239 (34%), Gaps = 36/239 (15%)

Query: 20  PARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAA-- 77
           P  P +       A P  +++ S A +  SS   P  IHP  + +++ S    AP ++  
Sbjct: 452 PDSPPLQAPLSLPASPPLQTSLSPAVSPLSS---PLTIHPLQALSSLASHSPQAPLSSLI 508

Query: 78  -------PRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSP-P 129
                    L P  L   PA         L + A       +A  T       P P+P P
Sbjct: 509 MPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 130 LQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGP---PR 186
           LQ            A P  +PL  PP   P + + P  ++ P  A     G   P   P 
Sbjct: 569 LQ------------APP--SPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPL 614

Query: 187 GDPRPRAP-----RPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240
             P P+AP      P   P   PA      L+ PSP   N   A      P   PP PP
Sbjct: 615 ATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNA-LAVHLLQAPFSPPPSPP 672


>gi|14790190 spen homolog, transcriptional regulator [Homo sapiens]
          Length = 3664

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 61/245 (24%), Positives = 87/245 (35%), Gaps = 32/245 (13%)

Query: 7    TEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAV 66
            +E+  A  GV + P   +  +Q G  A   P      A AA +  P P  +  P      
Sbjct: 3207 SEQPRAADGVVKVPPASKAPQQPGKEAAKTPD-----AKAAPTPTPAPVPVPVPLP---- 3257

Query: 67   HSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRR-RPG 125
                  APA AP    R+L   P+    L G  L       H  +    +G  ++  R G
Sbjct: 3258 ------APAPAPHGEARILTVTPSNQ--LQGLPLTPPVVVTHGVQIVHSSGELFQEYRYG 3309

Query: 126  PSPPLQPRSRHPHTRYPRAVPEATPLR-------PPPGTRPRAKSRPGCRSSPF-PARSR 177
                  P ++  HT++P A     P R       PPP   P    +P   + P  PA   
Sbjct: 3310 DIRTYHPPAQLTHTQFPAASSVGLPSRTKTAAQGPPPEGEPLQPPQPVQSTQPAQPAPPC 3369

Query: 178  TPGEAGPPRGDPRPRAPRPGDHPR------RSPALRETPSLSPPSPGRRNGKRAAGKGTT 231
             P + G P   P  + P+     +        P L   P+  PP P  +  +  A  G T
Sbjct: 3370 PPSQLGQPGQPPSSKMPQVSQEAKGTQTGVEQPRLPAGPANRPPEPHTQVQRAQAETGPT 3429

Query: 232  PQPQP 236
              P P
Sbjct: 3430 SFPSP 3434



 Score = 33.1 bits (74), Expect = 0.38
 Identities = 64/277 (23%), Positives = 95/277 (34%), Gaps = 50/277 (18%)

Query: 6    ATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAA 65
            A  +A AP G+A     P   ++   +A     +A+  +     S  P  F  PP     
Sbjct: 2188 AAYKADAPEGLA-----PEDRDKPAHQASETELAAAIGSIINDISGEPENFPAPPPYPGE 2242

Query: 66   VHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPG 125
              + L+              AGA A   +  G     A +   + EAA  + R     P 
Sbjct: 2243 SQTDLQPP------------AGAQALQPSEEGMETDEAVSGILETEAATESSRPPVNAPD 2290

Query: 126  PS--PPLQPRSRHPHTRYPRAVPEA--------TPLRPPPGTRPRAKSRPGCRSSP---F 172
            PS  P     +R   +    +VPEA        T +R   G +   +SR    ++     
Sbjct: 2291 PSAGPTDTKEARGNSSETSHSVPEAKGSKEVEVTLVRKDKGRQKTTRSRRKRNTNKKVVA 2350

Query: 173  PARSRTPGEAGPPRGDP----------RPRAP---RPGDHPRRSPA------LRETPSLS 213
            P  S  P E+   +G+            P AP   +  + P  +P       L + PS  
Sbjct: 2351 PVESHVP-ESNQAQGESPAANEGTTVQHPEAPQEEKQSEKPHSTPPQSCTSDLSKIPSTE 2409

Query: 214  PPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMA 250
              S      +R   K + P   PPPP  A   EE  A
Sbjct: 2410 NSSQEISVEERTPTKASVPPDLPPPPQPAPVDEEPQA 2446



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 51/235 (21%), Positives = 80/235 (34%), Gaps = 21/235 (8%)

Query: 4    EKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSR 63
            E+  +EAAA P        PR      +R   +    + A   A +  PP G+  P S +
Sbjct: 1935 ERELQEAAAVP------TTPRRGRPPKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQK 1988

Query: 64   AAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRR 123
             A     +         +      A    G   G +  +    A ++EA +   +R R+ 
Sbjct: 1989 TAAGGGPQGKKGKNEPKVDATRPEATTEVGPQIGVKESSMEPKAAEEEAGSEQ-KRDRKD 2047

Query: 124  PGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAG 183
             G         ++P    P  V E  P         R +SR    +    A  +    A 
Sbjct: 2048 AG-------TDKNPPETAPVEVVEKKPAPEKNSKSKRGRSRNSRLAVDKSASLKNVDAAV 2100

Query: 184  PPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPP 238
             PRG     A + G+  R S  +  +P  S  SP + +G  +  K     P   P
Sbjct: 2101 SPRG----AAAQAGE--RESGVVAVSPEKS-ESPQKEDGLSSQLKSDPVDPDKEP 2148



 Score = 29.3 bits (64), Expect = 5.5
 Identities = 45/173 (26%), Positives = 69/173 (39%), Gaps = 17/173 (9%)

Query: 74   PAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPR 133
            P A P  LP  +   P+     A   +   AAA  D  +  P+G      PGPS    PR
Sbjct: 2987 PPALPSKLPTEVNHVPSGPSIPADRTVSHLAAAKLDAHSPRPSG------PGPSS--FPR 3038

Query: 134  SRHPHTRYPRAV-PEATPLRPPPGTRPRAKSRPGCRSS---PFPARSRTPGEAGPPRGDP 189
            + HP +    A+   AT +       P+  S      S   P  + ++T   +   +G+ 
Sbjct: 3039 ASHPSSTASTALSTNATVMLAAGIPVPQFISSIHPEQSVIMPPHSITQTVSLSHLSQGEV 3098

Query: 190  RPRAPRPGDHPRRSPALRETPSLSPPSP--GRRNGKRAAGKGTTPQPQPPPPP 240
            R   P     P  + ++R     SP +P   ++   RA  + +TPQP P   P
Sbjct: 3099 RMNTP---TLPSITYSIRPEALHSPRAPLQPQQIEVRAPQRASTPQPAPAGVP 3148



 Score = 28.5 bits (62), Expect = 9.4
 Identities = 38/134 (28%), Positives = 49/134 (36%), Gaps = 21/134 (15%)

Query: 124  PGPSPPLQPRSRHPHTRYPRAV--------PEATPLRPPPGTRPRAKSRPGCRSSPFPAR 175
            P PS PL  R+R  + R   A         P   P+  P  TR R + R    ++  P  
Sbjct: 1890 PEPSLPLS-RTRRRNVRSVYATMGDHENRSPVKEPVEQPRVTRKRLE-RELQEAAAVPTT 1947

Query: 176  SRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGR--RNGKRAAGKGTTPQ 233
                    P RG P P+  R  D    + A     +L PP   R  R+ K AAG G   +
Sbjct: 1948 --------PRRGRP-PKTRRRADEEEENEAKEPAETLKPPEGWRSPRSQKTAAGGGPQGK 1998

Query: 234  PQPPPPPCATRREE 247
                 P     R E
Sbjct: 1999 KGKNEPKVDATRPE 2012


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 65/255 (25%), Positives = 86/255 (33%), Gaps = 36/255 (14%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRA 72
           P GV   P  P      GS       +  + +    S+ PPP  IH       V      
Sbjct: 705 PNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPP 764

Query: 73  APAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQP 132
            P   P  LP      P  T     S    A       +AA PT         P+PP+ P
Sbjct: 765 PPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVT---QAAPPT---------PTPPVPP 812

Query: 133 RSRHPH--TRYPRAVPEATPLRPPPGTRPRAKS----RPGCRSSPFPA-----RSRTPGE 181
             + P     Y    P   P+  PP T P+ +S     P    SP P+      S+ P  
Sbjct: 813 AKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP 872

Query: 182 AGPPRGDPRPRAPRPGD-HPRRSPALRE------------TPSLSPPSPGRRNGKRAAGK 228
             PP  + +P  P P +  P+  PA++             +P   PP P           
Sbjct: 873 PTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPP 932

Query: 229 GTTPQPQPPPPPCAT 243
              P P PPPPP A+
Sbjct: 933 SPVPAPPPPPPPTAS 947



 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 56/238 (23%), Positives = 84/238 (35%), Gaps = 53/238 (22%)

Query: 13   PPGVAESPARPRVNEQWGSRAHPNPRS-ASSAAAAASSSFPPPGFIHPPSSRAAVHSRLR 71
            PP     P  P+  + + ++  P+P S   S     +S FPPP     P+  A     L+
Sbjct: 831  PPVPVPPPTLPK-QQSFCAKPPPSPLSPVPSVVKQIASQFPPP-----PTPPAMESQPLK 884

Query: 72   AAPA-AAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPL 130
              PA  AP+  P V A    +  ++                            P PSP  
Sbjct: 885  PVPANVAPQSPPAVKAKPKWQPSSI----------------------------PVPSPDF 916

Query: 131  QPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPR 190
             P        +P   P   P  PPP         P   +SP P +S +PG+       P 
Sbjct: 917  PPPPPESSLVFPPPPPSPVPAPPPP---------PPPTASPTPDKSGSPGKKTSKTSSPG 967

Query: 191  PRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGT------TPQPQPPPPPCA 242
             + P P   P+R+ +++ +     P P R +      K T      +P  +  PPP A
Sbjct: 968  GKKPPP--TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAA 1023



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 51/211 (24%), Positives = 77/211 (36%), Gaps = 32/211 (15%)

Query: 39  SASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGS 98
           S+S  + ++SSS P     H   S + V     A    +  ++  V + A  R     G+
Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKR-----GT 585

Query: 99  RLRAAAAAAHDQEAAAPTGRRWRRRPGPS--PPLQPRSRHPHTRYPRAVPEATPLRPPPG 156
           +L  ++ A  +             RP  S  PPL P+   P    P    + +P  PPP 
Sbjct: 586 QLEESSKARMES----------MNRPYTSLVPPLSPQ---PKIVTPYTASQPSPPLPPPP 632

Query: 157 TRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSL-SPP 215
             P     P     P P     P ++ P  G   P   +     R   A + + +L  PP
Sbjct: 633 PPPPPPPPP-----PPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPP 687

Query: 216 SPGRRNGKRAAGK------GTTPQPQPPPPP 240
           +P     +    +      G  P P PPPPP
Sbjct: 688 TPPVMQSQSVKPQILVPPNGVVPPPPPPPPP 718


>gi|95147559 ankyrin repeat domain 43 [Homo sapiens]
          Length = 549

 Score = 54.3 bits (129), Expect = 2e-07
 Identities = 69/225 (30%), Positives = 82/225 (36%), Gaps = 37/225 (16%)

Query: 13  PPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFP----PPGFIHPPSSRAAVHS 68
           PPG A  P++P             PRSAS+  A      P    PPG +  P+       
Sbjct: 95  PPGAAAQPSKPTSTVL--------PRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPG 146

Query: 69  RLRAAPA-------AAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWR 121
              + PA       A P L    LA A  R  A A    RA +      EAA+P      
Sbjct: 147 GPASEPAQPPGERSADPPLPALELAQATERPSADAAPPPRAPS------EAASPCSDPPD 200

Query: 122 RRPGPSPPLQPRSRHPHTRYPRAVPEATPLR---PPPGTRPRAKSRPGCRSSPFPARSRT 178
             PGP     P  + P     R VP    LR     PG R +    P  RSSP   R  +
Sbjct: 201 AEPGPGAAKGPPQQKPCMLPVRCVPAPATLRLRAEEPGLRRQLSEEPSPRSSPLLLRRLS 260

Query: 179 PGEA------GPPRGDPRPRAPRPGDHPR-RSPALRETPSLSPPS 216
             E+      GP R     R  R G  PR  SP   E P+  PPS
Sbjct: 261 VEESGLGLGLGPGRSPHLRRLSRAG--PRLLSPDAEELPAAPPPS 303



 Score = 32.0 bits (71), Expect = 0.85
 Identities = 56/210 (26%), Positives = 66/210 (31%), Gaps = 34/210 (16%)

Query: 126 PSPPLQPRSRH-----PHTRYPRAVPE-------ATPLRPPPGTRPRAKSRPGCRSS--P 171
           P+  + PRS       P  R PR V           P   P G        PG RS+  P
Sbjct: 105 PTSTVLPRSASAPGAPPLVRVPRPVEPPGDLGLPTEPQDTPGGPASEPAQPPGERSADPP 164

Query: 172 FPA------RSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRA 225
            PA        R   +A PP     PRAP     P   P   E      P PG   G   
Sbjct: 165 LPALELAQATERPSADAAPP-----PRAPSEAASPCSDPPDAE------PGPGAAKGPPQ 213

Query: 226 AGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGFGRSEQHLRGLTLII 285
                 P    P P     R E+  LR   R  S     R++     R      GL L +
Sbjct: 214 QKPCMLPVRCVPAPATLRLRAEEPGLR---RQLSEEPSPRSSPLLLRRLSVEESGLGLGL 270

Query: 286 SCTLSHKPASLRRSGTQAWGPRGLPLRATP 315
               S     L R+G +   P    L A P
Sbjct: 271 GPGRSPHLRRLSRAGPRLLSPDAEELPAAP 300



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 23/80 (28%), Positives = 27/80 (33%), Gaps = 4/80 (5%)

Query: 160 RAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSP-G 218
           R K RP     P PA    PG A  P        PR    P   P +R    + PP   G
Sbjct: 80  RKKPRP---PEPEPAPFGPPGAAAQPSKPTSTVLPRSASAPGAPPLVRVPRPVEPPGDLG 136

Query: 219 RRNGKRAAGKGTTPQPQPPP 238
                +    G   +P  PP
Sbjct: 137 LPTEPQDTPGGPASEPAQPP 156


>gi|239754458 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 180

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/179 (31%), Positives = 67/179 (37%), Gaps = 40/179 (22%)

Query: 41  SSAAAAASSSFPP------PGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGA 94
           ++A+  + S FPP      PG    PS RAA    L+  P  AP  L R     P   G 
Sbjct: 8   NAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRP---KPVSRGP 64

Query: 95  LAGSRLRAAAAAAHDQEAAAPTGRRWRR---RPGP-SPPLQPRSRHPHTRYPRAVPEATP 150
            AG R                    W +   RPGP   PLQ R+   H     + P ATP
Sbjct: 65  RAGLR-------------------EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 151 L------RPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRA--PRPGDHPR 201
                  RPP  T  R    PG  +    +R   P +  PP  D  PR   PRP   PR
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR 164



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 28/96 (29%), Positives = 34/96 (35%), Gaps = 6/96 (6%)

Query: 154 PPGTRPRAKSR---PGCRSSPFPARSRTPGEAGPPRGDPRP--RAPRPGDHPRRSPALRE 208
           PP  R R       P  R++  P   + P  A    G P+P  R PR G         R 
Sbjct: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78

Query: 209 TPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATR 244
            P L  P   R       G  + P   P PP C+ R
Sbjct: 79  GP-LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113


>gi|239749008 PREDICTED: hypothetical protein XP_002346879 [Homo
           sapiens]
          Length = 180

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/179 (31%), Positives = 67/179 (37%), Gaps = 40/179 (22%)

Query: 41  SSAAAAASSSFPP------PGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGA 94
           ++A+  + S FPP      PG    PS RAA    L+  P  AP  L R     P   G 
Sbjct: 8   NAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRP---KPVSRGP 64

Query: 95  LAGSRLRAAAAAAHDQEAAAPTGRRWRR---RPGP-SPPLQPRSRHPHTRYPRAVPEATP 150
            AG R                    W +   RPGP   PLQ R+   H     + P ATP
Sbjct: 65  RAGLR-------------------EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 151 L------RPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRA--PRPGDHPR 201
                  RPP  T  R    PG  +    +R   P +  PP  D  PR   PRP   PR
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR 164



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 28/96 (29%), Positives = 34/96 (35%), Gaps = 6/96 (6%)

Query: 154 PPGTRPRAKSR---PGCRSSPFPARSRTPGEAGPPRGDPRP--RAPRPGDHPRRSPALRE 208
           PP  R R       P  R++  P   + P  A    G P+P  R PR G         R 
Sbjct: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78

Query: 209 TPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATR 244
            P L  P   R       G  + P   P PP C+ R
Sbjct: 79  GP-LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113


>gi|239743028 PREDICTED: hypothetical protein XP_002342721 [Homo
           sapiens]
          Length = 180

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 56/179 (31%), Positives = 67/179 (37%), Gaps = 40/179 (22%)

Query: 41  SSAAAAASSSFPP------PGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGA 94
           ++A+  + S FPP      PG    PS RAA    L+  P  AP  L R     P   G 
Sbjct: 8   NAASCRSGSHFPPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRP---KPVSRGP 64

Query: 95  LAGSRLRAAAAAAHDQEAAAPTGRRWRR---RPGP-SPPLQPRSRHPHTRYPRAVPEATP 150
            AG R                    W +   RPGP   PLQ R+   H     + P ATP
Sbjct: 65  RAGLR-------------------EWPQQPWRPGPLGAPLQDRAPSAHVPGSASRPTATP 105

Query: 151 L------RPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRA--PRPGDHPR 201
                  RPP  T  R    PG  +    +R   P +  PP  D  PR   PRP   PR
Sbjct: 106 APPRCSRRPPTTTVSRVAPSPGRPAGLHRSREPRPQDGTPPPVDTPPRTARPRPAFTPR 164



 Score = 35.4 bits (80), Expect = 0.077
 Identities = 28/96 (29%), Positives = 34/96 (35%), Gaps = 6/96 (6%)

Query: 154 PPGTRPRAKSR---PGCRSSPFPARSRTPGEAGPPRGDPRP--RAPRPGDHPRRSPALRE 208
           PP  R R       P  R++  P   + P  A    G P+P  R PR G         R 
Sbjct: 19  PPAARGRLPGETLSPSPRAAALPPLQQRPPGAPGALGRPKPVSRGPRAGLREWPQQPWRP 78

Query: 209 TPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATR 244
            P L  P   R       G  + P   P PP C+ R
Sbjct: 79  GP-LGAPLQDRAPSAHVPGSASRPTATPAPPRCSRR 113


>gi|14149696 SEC31 homolog B [Homo sapiens]
          Length = 1179

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 69/257 (26%), Positives = 100/257 (38%), Gaps = 37/257 (14%)

Query: 1   MCREKATEEAAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPP 60
           M   ++ E+   P GV+  PA      Q+ +        A+  + A + SF P     PP
Sbjct: 719 MVLNRSLEQLRGPHGVSPGPATTYRVTQYANLL------AAQGSLATAMSFLPRDCAQPP 772

Query: 61  SSRAAVHSRLRAAPAAA-------PRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAA 113
             +  +  RL  A  +A       P   PR++ GA   +   +  RL   +  +H     
Sbjct: 773 VQQ--LRDRLFHAQGSAVLGQQSPPFPFPRIVVGATLHSKETSSYRL--GSQPSHQVPTP 828

Query: 114 APTGRRWRRRPGPSPPLQPRSRHPH--------TRYPRAVPEAT-PLRPPPGTRPRAKSR 164
           +P  R +  +  P+ PL P    P+        + Y    P+A  PL   PG RP A S+
Sbjct: 829 SPRPRVFTPQSSPAMPLAPSHPSPYQGPRTQNISDYRAPGPQAIQPLPLSPGVRP-ASSQ 887

Query: 165 PGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHPR----RSPALRETPSLSPPSPGRR 220
           P         R + P   G P   P P +P P   P      S +L ETP L P  P R 
Sbjct: 888 PQLLGGQ---RVQVPNPVGFPGTWPLPGSPLPMACPGIMRPGSTSLPETPRLFPLLPLRP 944

Query: 221 NGKRAAGKGTTPQPQPP 237
            G    G+  +  P PP
Sbjct: 945 LG---PGRMVSHTPAPP 958


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 78/284 (27%), Positives = 99/284 (34%), Gaps = 81/284 (28%)

Query: 7   TEEAAAP-PGVAESPARPRVNEQWGSRAHPN--------------PRSASSAAAAASSSF 51
           +  AAAP P V+ +  RP+ +      + P               P + SS     SSS 
Sbjct: 117 SSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHSSSA 176

Query: 52  PPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQE 111
           PPP    PP  R     R  A P   P                     + ++ A A+++E
Sbjct: 177 PPP----PPPGR-----RANAPPTPLP---------------------MHSSKAPAYNRE 206

Query: 112 AAAPTGRRWRRRPG-PSPPLQPRSRHPHTRY--------PRAVPEATPLRPPPGTRPRAK 162
              P     R  PG   PP  P  + P +              P   P R PPG  P   
Sbjct: 207 KPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGV-PNGP 265

Query: 163 SRPGCRSSP-FPARS-----RTPGEAGPPRG--DPRPRAPRPGDHPRRSPA-LRETPSLS 213
           S P   S+P  P R      +TPG   P RG   P P +  P     R P   R+ PS  
Sbjct: 266 SSPTNESAPELPQRHNSLHRKTPG---PVRGLAPPPPTSASPSLLSNRPPPPARDPPSRG 322

Query: 214 ----PPSPGRRNGKRAA----------GKGTTPQPQPPPPPCAT 243
               PP P  RNG R A          G     + +PPPPP  T
Sbjct: 323 AAPPPPPPVIRNGARDAPPPPPPYRMHGSEPPSRGKPPPPPSRT 366



 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 42/129 (32%), Positives = 52/129 (40%), Gaps = 13/129 (10%)

Query: 122 RRPGPSPPLQPRSRHPH--TRYPRA-VPEATPL-RP--PPGTRPRAKSRPGCRSSPFPAR 175
           R   P PP+   S  P   T   RA +PE   + RP  P  +RP   S  G + S     
Sbjct: 119 RAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTTSSTGMKHS----- 173

Query: 176 SRTPGEAGPPRGDPRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQ 235
           S  P    P R    P  P P  H  ++PA      L PP+PG+R      G    P  +
Sbjct: 174 SSAPPPPPPGRRANAPPTPLPM-HSSKAPAYNREKPL-PPTPGQRLHPGREGPPAPPPVK 231

Query: 236 PPPPPCATR 244
           PPP P   R
Sbjct: 232 PPPSPVNIR 240



 Score = 40.0 bits (92), Expect = 0.003
 Identities = 48/178 (26%), Positives = 63/178 (35%), Gaps = 19/178 (10%)

Query: 14  PGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAA 73
           PG    PA P V      +  P+P +  +  +  S + PPP +  PP       S    +
Sbjct: 219 PGREGPPAPPPV------KPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNES 272

Query: 74  PAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPR 133
               P+    +    P     LA     +A+ +        P      R   P PP  P 
Sbjct: 273 APELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPP-PPV 331

Query: 134 SRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRP 191
            R+          +A P  PPP  R    S P  R  P P  SRTP  AGPP   P P
Sbjct: 332 IRN-------GARDAPP--PPPPYRMHG-SEPPSRGKPPPPPSRTP--AGPPPPPPPP 377


>gi|19924099 synapsin I isoform Ia [Homo sapiens]
          Length = 705

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 60/227 (26%), Positives = 81/227 (35%), Gaps = 35/227 (15%)

Query: 52  PPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAPARTGALAGSRLRAAAAAAHDQE 111
           PP G   P    +   +  + A  AAP    +     P   G  A    R  A+ +  ++
Sbjct: 498 PPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASPSPQRQ 557

Query: 112 AAAPTGRRWRRRPGPSPPLQPRSRHPHTRYPRAVPEATPLRPPPGTRPRAKSRPGCRSSP 171
           A  P   R     GP+PP    S  P    P       P + PPG  P   +R   ++ P
Sbjct: 558 AGPPQATRQTSVSGPAPP--KASGAP----PGGQQRQGPPQKPPG--PAGPTRQASQAGP 609

Query: 172 FPARSRTPGEAGPPRGD-PRPRAPRPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGT 230
            P         GPP    PRP  P P   P+  P L + PS   P P       AAG   
Sbjct: 610 VP-------RTGPPTTQQPRPSGPGPAGRPK--PQLAQKPSQDVPPP----ATAAAGGPP 656

Query: 231 TPQ-------------PQPPPPPCATRREEDMALRTRDRTSSRGTVF 264
            PQ             P+P PP  +  ++E  A   R    S  ++F
Sbjct: 657 HPQLNKSQSLTNAFNLPEPAPPRPSLSQDEVKAETIRSLRKSFASLF 703



 Score = 49.7 bits (117), Expect = 4e-06
 Identities = 61/228 (26%), Positives = 77/228 (33%), Gaps = 21/228 (9%)

Query: 30  GSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSRLRAAPAAAPRLLPRVLAGAP 89
           G  +H    S  +      +S  P G   PP+ +          P   P+     L   P
Sbjct: 429 GRGSHGQTPSPGALPLGRQTSQQPAG---PPAQQRPPPQGGPPQPGPGPQRQGPPLQQRP 485

Query: 90  ARTGALAGSRLRAAAAAAHDQEAAAPTGRRWRRRPGPSPPLQPRSRH--PHTRYPRAVPE 147
              G    S L   A +   Q   +PT    +     +PP Q + R   P    P A P 
Sbjct: 486 PPQGQQHLSGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPA 545

Query: 148 ATPLRPPPGTR---PRAKSRPGCRSSPFP--ARSRTPG---EAGPPRGDPRPRAP----- 194
           A P   P   R   P   +R    S P P  A    PG     GPP+  P P  P     
Sbjct: 546 ARPPASPSPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQAS 605

Query: 195 RPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCA 242
           + G  PR  P   + P  S P P  R   + A K   P    PPP  A
Sbjct: 606 QAGPVPRTGPPTTQQPRPSGPGPAGRPKPQLAQK---PSQDVPPPATA 650



 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 14/176 (7%)

Query: 87  GAPARTGALA-GSRLRAAAAAAHDQEAAAPTGRRWRRRPGPS---PPLQPR-----SRHP 137
           G     GAL  G +     A    Q+   P G   +  PGP    PPLQ R      +H 
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQRPPPQGQQHL 493

Query: 138 HTRYPRA---VPEATPLRPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAP 194
               P A   +P+  P       +P +++ P  +     +R    G   PP   P P +P
Sbjct: 494 SGLGPPAGSPLPQRLPSPTSAPQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARP-PASP 552

Query: 195 RPGDHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMA 250
            P        A R+T S+S P+P + +G    G+     PQ PP P    R+   A
Sbjct: 553 SPQRQAGPPQATRQT-SVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQA 607



 Score = 34.3 bits (77), Expect = 0.17
 Identities = 34/121 (28%), Positives = 49/121 (40%), Gaps = 17/121 (14%)

Query: 153 PPPGTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPRPRAPRPGDHP-RRSPALRETPS 211
           P PG  P  +      + P PA+ R P     P+G P    P+PG  P R+ P L++   
Sbjct: 437 PSPGALPLGRQTSQQPAGP-PAQQRPP-----PQGGP----PQPGPGPQRQGPPLQQ--- 483

Query: 212 LSPPSPGRRNGKRAAGKGTTPQPQPPPPPCATRREEDMALRTRDRTSSRGTVFRAADWGF 271
             PP  G+++         +P PQ  P P  T   +  A +    T  +G   R    G 
Sbjct: 484 -RPPPQGQQHLSGLGPPAGSPLPQRLPSP--TSAPQQPASQAAPPTQGQGRQSRPVAGGP 540

Query: 272 G 272
           G
Sbjct: 541 G 541


>gi|126723060 zinc finger CCCH-type containing 4 [Homo sapiens]
          Length = 1303

 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 67/239 (28%), Positives = 96/239 (40%), Gaps = 35/239 (14%)

Query: 10   AAAPPGVAESPARPRVNEQWGSRAHPNPRSASSAAAAASSSFPPPGFIHPPSSRAAVHSR 69
            ++A PG ++ P+ PRV      +A  +PR      + ASS    PG    PS  A+    
Sbjct: 1058 SSAAPGSSDKPSDPRVR-----KAPTDPRLQKPTDSTASSRAAKPGPAEAPSPTASPSG- 1111

Query: 70   LRAAPAAAPRLLPRVLA-------GAPARTGALAGSRL---RAAAAAAHDQEAAAPTGRR 119
              A+P A     PRVLA       G   ++  L+G  L   R   A     E AA TG +
Sbjct: 1112 -DASPPATAPYDPRVLAAGGLGQGGGGGQSSVLSGISLYDPRTPNAGGKATEPAADTGAQ 1170

Query: 120  WRRRPGPSPPLQPRSRHPHTRYPRAV--PEATPLRPPPGT---RPRAKSRPGCRSSPFP- 173
             +   G       +++ P      A+  PE        GT   R  + +RP  +++  P 
Sbjct: 1171 PKGAEGNGKSSASKAKEPPFVRKSALEQPETGKAGADGGTPTDRYNSYNRPRPKAAAAPA 1230

Query: 174  ARSRTPGEAGPPRGDPRPRAPRPGDHPRRSPAL----RETPSLSPPSPGRRNGKRAAGK 228
            A + TP    PP G P    P+PG H    P L    ++TP     SP   N     G+
Sbjct: 1231 ATTATP----PPEGAP----PQPGVHNLPVPTLFGTVKQTPKTGSGSPFAGNSPAREGE 1281



 Score = 30.4 bits (67), Expect = 2.5
 Identities = 20/57 (35%), Positives = 24/57 (42%), Gaps = 13/57 (22%)

Query: 188 DPRPRAPRPG----DHPRRSPALRETPSLSPPSPGRRNGKRAAGKGTTPQPQPPPPP 240
           +P P+ P PG      P R P         P +P   NG+   G    P P PPPPP
Sbjct: 505 NPLPKPP-PGVGLLPTPPRPPG--------PQAPTSPNGRPMQGGPPPPPPPPPPPP 552



 Score = 29.6 bits (65), Expect = 4.2
 Identities = 44/198 (22%), Positives = 60/198 (30%), Gaps = 42/198 (21%)

Query: 110 QEAAAPTGRRWRRRPGPSP------------------PLQPRSRHPHTRYPRAVPEATPL 151
           Q   +P GR  +  P P P                  PL P+       Y + +P    +
Sbjct: 527 QAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVHEPLSPQQLQQQDMYNKKIPSLFEI 586

Query: 152 RPPPGTRPRAKSRPGCRSSPFPARSRTPGEAGP--------PRGDPRPRAPRPGDHPRRS 203
              P    +   + G R   FP     PG  GP        P G P      P  HP   
Sbjct: 587 VVRP--TGQLAEKLGVR---FPGPGGPPGPMGPGPNMGPPGPMGGPMHPDMHPDMHPDMH 641

Query: 204 PALRET--------PSLSPPSPGRRNG--KRAAGKGTTPQP-QPPPPPCATRREEDMALR 252
           P +           P ++P  P    G      G G +P     PP P A    E+   +
Sbjct: 642 PDMHADMHADMPMGPGMNPGPPMGPGGPPMMPYGPGDSPHSGMMPPIPPAQNFYENFYQQ 701

Query: 253 TRDRTSSRGTVFRAADWG 270
                   G +  A D+G
Sbjct: 702 QEGMEMEPGLLGDAEDYG 719



 Score = 28.9 bits (63), Expect = 7.2
 Identities = 21/65 (32%), Positives = 21/65 (32%), Gaps = 3/65 (4%)

Query: 156 GTRPRAKSRPGCRSSPFPARSRTPGEAGPPRGDPR---PRAPRPGDHPRRSPALRETPSL 212
           G  P  K  PG    P P R   P     P G P    P  P P   P   P     P  
Sbjct: 503 GINPLPKPPPGVGLLPTPPRPPGPQAPTSPNGRPMQGGPPPPPPPPPPPPGPPQMPMPVH 562

Query: 213 SPPSP 217
            P SP
Sbjct: 563 EPLSP 567


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,118,530
Number of Sequences: 37866
Number of extensions: 1613947
Number of successful extensions: 25874
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 482
Number of HSP's successfully gapped in prelim test: 2404
Number of HSP's that attempted gapping in prelim test: 12336
Number of HSP's gapped (non-prelim): 10597
length of query: 350
length of database: 18,247,518
effective HSP length: 103
effective length of query: 247
effective length of database: 14,347,320
effective search space: 3543788040
effective search space used: 3543788040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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