BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] (816 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 1654 0.0 gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 1629 0.0 gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 1031 0.0 gi|163965366 nascent polypeptide-associated complex alpha subuni... 212 1e-54 gi|116284392 mucin 2 precursor [Homo sapiens] 162 1e-39 gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 148 2e-35 gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 148 2e-35 gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 148 2e-35 gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 148 2e-35 gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 145 1e-34 gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 142 1e-33 gi|47132519 Ras association and pleckstrin homology domains 1 is... 142 1e-33 gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 140 5e-33 gi|112421108 capicua homolog [Homo sapiens] 139 1e-32 gi|110832843 TBP-associated factor 4 [Homo sapiens] 138 2e-32 gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 138 2e-32 gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 137 3e-32 gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 135 2e-31 gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 134 3e-31 gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 134 3e-31 gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 134 3e-31 gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 134 3e-31 gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 132 1e-30 gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapi... 128 2e-29 gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 126 7e-29 gi|55750053 atrophin-1 [Homo sapiens] 125 1e-28 gi|55750041 atrophin-1 [Homo sapiens] 125 1e-28 gi|150170670 piccolo isoform 2 [Homo sapiens] 124 3e-28 gi|150378539 piccolo isoform 1 [Homo sapiens] 124 3e-28 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 124 4e-28 >gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens] Length = 816 Score = 1654 bits (4284), Expect = 0.0 Identities = 816/816 (100%), Positives = 816/816 (100%) Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL Sbjct: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 120 Query: 121 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL Sbjct: 121 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 180 Query: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 Query: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300 Query: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA Sbjct: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360 Query: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP Sbjct: 361 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 Query: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA Sbjct: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480 Query: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA Sbjct: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPA 540 Query: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP Sbjct: 541 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTP 600 Query: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS Sbjct: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGS 660 Query: 661 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 720 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG Sbjct: 661 ADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 720 Query: 721 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLS 780 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLS Sbjct: 721 ALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLS 780 Query: 781 PLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 816 PLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH Sbjct: 781 PLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 816 >gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 855 Score = 1629 bits (4219), Expect = 0.0 Identities = 815/855 (95%), Positives = 816/855 (95%), Gaps = 39/855 (4%) Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 61 RAGGIGGATIPESAPRAGPTRT---------SRPPASGRGERAPPAKNTSPGPVSSPGRA 111 RAGGIGGATIPESAPRAGPTR+ SRPPASGRGERAPPAKNTSPGPVSSPGRA Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120 Query: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 171 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300 Query: 292 SSPLATPSPSA------------------------------PPSPSAPPSLQTLPSPPAT 321 SSPLATPSPSA PPSPSAPPSLQTLPSPPAT Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360 Query: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL Sbjct: 361 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 420 Query: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ Sbjct: 421 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 480 Query: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 501 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG Sbjct: 481 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPG 540 Query: 502 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 561 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG Sbjct: 541 QAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG 600 Query: 562 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 621 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD Sbjct: 601 PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPD 660 Query: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG Sbjct: 661 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 720 Query: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 741 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE Sbjct: 721 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAE 780 Query: 742 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 801 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA Sbjct: 781 GAAGGSGGGPGGAEGGGVTGGARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVA 840 Query: 802 SPQGDWTVVEVETFH 816 SPQGDWTVVEVETFH Sbjct: 841 SPQGDWTVVEVETFH 855 >gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens] Length = 1124 Score = 1031 bits (2667), Expect = 0.0 Identities = 583/894 (65%), Positives = 618/894 (69%), Gaps = 107/894 (11%) Query: 8 AKAGAAAR-TPAARAPGLLTPRPPGSPRP-------PPPVTPAALRVLGAAGAVGRKPLA 59 A++G +AR TP A P P P+P PP VTP A G + PLA Sbjct: 253 ARSGPSARGTPRA-------PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305 Query: 60 ---------------ERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGP 104 + A AT+P S P A P + P S APP+ T P P Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS-----APPSLQTLPSP 360 Query: 105 VSSP---GRASGTTRP---GPLGQKGLRISAEETVARGKATEAPKRSALSA-GARRDTSG 157 ++P S TT P P Q I ++ P ALS+ A Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420 Query: 158 PTPGTPSPAMARRSRAAGTEVGLP-RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216 PT + R + P RPA + PP + P +S ++ P+ + Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480 Query: 217 RRPSAGGGLQRPASRSLSSSATPLSS--------PARSGPSARGTPRAPAHPSQPKPKGL 268 P LQ +S + S PLSS + P + TP PA + P + L Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP--PASLTTPPLENL 538 Query: 269 QALRPPQVTPPRKDAAPALGP-LSSSPLATPSP-SAPPSPSAPPSLQTLPSPPATPPSQA 326 +L PP P + +AP P L + P P P APPSP P +T PS ATPP QA Sbjct: 539 PSLAPP---PLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPET-PSSIATPPPQA 594 Query: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386 +L SP LQ LPSPPLSPLATPPPQAPP LALPPLQAPPSPPASPPLSPLATPSP Sbjct: 595 PPALASPPLQG----LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650 Query: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 710 Query: 447 PASPPMSPSATPPPQAPPPLAAPPLQ---------------------------------- 472 PASPPMSPSATPPPQAPPPLAAPPLQ Sbjct: 711 PASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP 770 Query: 473 ----------LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ Sbjct: 771 SPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 830 Query: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 890 Query: 583 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 642 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF Sbjct: 891 TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 950 Query: 643 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 702 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA Sbjct: 951 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGA 1010 Query: 703 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 762 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG Sbjct: 1011 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 1070 Query: 763 ARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 816 ARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH Sbjct: 1071 ARAALSDAELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDWTVVEVETFH 1124 Score = 849 bits (2193), Expect = 0.0 Identities = 537/968 (55%), Positives = 563/968 (58%), Gaps = 220/968 (22%) Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE Sbjct: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 Query: 61 RAGGIGGATIPESAPRAGPTRT---------SRPPASGRGERAPPAKNTSPGPVSSPGRA 111 RAGGIGGATIPESAPRAGPTR+ SRPPASGRGERAPPAKNTSPGPVSSPGRA Sbjct: 61 RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRA 120 Query: 112 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 171 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS Sbjct: 121 SGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRS 180 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR Sbjct: 181 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 240 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS Sbjct: 241 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 300 Query: 292 SSPLATPSPS---------------------------------APPSPSAPPSLQTLPSP 318 SSPLATPSPS APPSPSAPPSLQTLPSP Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360 Query: 319 PATPPS----------------------------------------------QATTSLGS 332 PATPPS QATTSLGS Sbjct: 361 PATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGS 420 Query: 333 PTLQATHSFL-------------PSPPLS-PLATPPPQAPPAL-ALPPLQAPPSPPASPP 377 PTLQATHSFL PS P S P +PP QAP +L A PPLQ SP SP Sbjct: 421 PTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPL 480 Query: 378 LSPLATPSPQAPNALAVHLLQAPFS-------------PPPS------------------ 406 SPL QA ++LA H QAP S PPS Sbjct: 481 SSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPS 540 Query: 407 ---PPVQAPFSP---------------PASPPVSPSATPPSQAPPSLAAPPLQVPP---S 445 PP+Q +P P P SP TPP + P S+A PP Q PP S Sbjct: 541 LAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALAS 600 Query: 446 PP----ASPPMSPSATPPPQAPPPLAAPPLQ-------------LAKPPPQAPPALATPP 488 PP SPP+SP ATPPPQAPP LA PPLQ LA P PQAP ALA Sbjct: 601 PPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHL 660 Query: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 LQA SPP S P QAPFSP AS P+SP ATPP QAPP LAAP LQVPPSPPASP + Sbjct: 661 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 720 Query: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST--------LSGPDLAGHSSSATSTP 600 PP P + P L + P PP P SPS+T L+ P L S S P Sbjct: 721 TPPPQAPPPLAAPP---LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLP 777 Query: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG----APGAPLPWPP-A 655 A PPP A A P + P+PP +F G +P A LP P A Sbjct: 778 M-----------SPLAKPPPQAPPALATPPLQAL-PSPPASFPGQAPFSPSASLPMSPLA 825 Query: 656 TGPGSADGLCTIYETEGPESATPAPGAL------DPGPSPGTSGGKAAAGAGAG---ASS 706 T P A + + P S +P PGP SG + G S Sbjct: 826 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 885 Query: 707 RSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAA 766 RSP G + H S T + E G G GGA AA Sbjct: 886 RSPSSTLSG--------PDLAGHSSSAT---STPEELRGYDSGPEGGAAASPPPDAELAA 934 Query: 767 LSDAELGR 774 A R Sbjct: 935 CHPAAWSR 942 >gi|163965366 nascent polypeptide-associated complex alpha subunit isoform a [Homo sapiens] Length = 2078 Score = 212 bits (539), Expect = 1e-54 Identities = 216/681 (31%), Positives = 283/681 (41%), Gaps = 117/681 (17%) Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES-APRAGPTRTSRP 85 P P P P P AL + ++ R A + IP S +P+ PT + Sbjct: 894 PFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKG-------IPASPSPKGAPTPPAAT 946 Query: 86 PASGRGERAPPAKNTSPGP--VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143 P S +G A P+ +P P + P G P P G + + G AT +PK Sbjct: 947 PPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPK 1006 Query: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203 PTP +P + S AA P P ++ P T K +A Sbjct: 1007 ------------GAPTPPAVTPPSPKGSPAA-----TPFPKGASTPPAATPPSPKGSPAA 1049 Query: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263 + P+ A PS GG PA+ SL + TP PA + PS +G P P+ P Sbjct: 1050 TPLPKGAPTTPAATLPSPKGG---PATPSLKGAPTP---PAATPPSPKGGPATPSPKGAP 1103 Query: 264 KPKGLQALRPPQ-----VTPPRKDA--APALGPLS-SSPLATPSP-SAPPSPSAPPSLQT 314 P A PP TPP K A PA P S LATP P AP +P+A P Sbjct: 1104 MP---PAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP---- 1156 Query: 315 LPSPP---ATPPSQA--TTSLGSPTLQATHSFLPSP---PLSPLATPPPQAPPALALPPL 366 PSP ATPP + TT +P PSP P +P AT PP LA P Sbjct: 1157 -PSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-PPSPKGGLATPSP 1214 Query: 367 QAPPSPPASPPLSP---LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 423 + P+ PA+ P SP LATPSP+ AP +P +PP +P PA+PP Sbjct: 1215 KGAPTTPAATPPSPKGGLATPSPKG----------APTTPAATPP--SPKGGPATPPPKG 1262 Query: 424 SATPPSQAPPS----LAAPPLQVPPSP----PASPPMSPSATPPPQAP-PPLAAPPLQLA 474 + TPP+ PPS LA PP + P+P P SP P+ +PP AP PP A PP Sbjct: 1263 APTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKG 1322 Query: 475 K---PPPQ---APPALATPPLQALPSPPASFPGQ--APFSPSASL-PMSPLATPPPQAPP 525 PPP+ PPA+ P + P+ PA+ P P +PS+ P P ATP + P Sbjct: 1323 SPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGP 1382 Query: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585 + PPSP P + +P+ PT S + L+ P P +R ++T S Sbjct: 1383 AM------TPPSPKRGPAIPSPKGDPT-------SPAVIPLSPKKAPATPVTREGAATPS 1429 Query: 586 GPDLAGHSSSATSTPEELR--GYDSGPEGG-AAASPPPDAELAACHPAAWSRGPAPPLAF 642 DL + TP L+ S P+GG A S D L A P + PAP Sbjct: 1430 KGDL----TPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVA 1485 Query: 643 -----RGAPGAPLPWPPATGP 658 + AP P P T P Sbjct: 1486 TSSSPKKAPATPAPMGAPTLP 1506 Score = 196 bits (499), Expect = 6e-50 Identities = 218/786 (27%), Positives = 291/786 (37%), Gaps = 130/786 (16%) Query: 14 ARTPAARAPGLLTPRPPGSPRPP---PP--------------VTPAALRVLGAAGAVGRK 56 A TP + G TP P G+P PP PP TP A+ G+ Sbjct: 967 AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026 Query: 57 PLAERAGGIGGATIPE--------SAPRAGPTRTSRPPASGRGERAPPAKNTSPGP--VS 106 P + A AT P P+ PT + S +G A P+ +P P + Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAAT 1086 Query: 107 SPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 166 P G P P G + + G AT K + + A + TP P Sbjct: 1087 PPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPK 1146 Query: 167 MARRSRAA---GTEVGLPRPAPSARPRPPTEGPRKSVSS-ASEHSTTEPSPAARRRPSAG 222 A + AA + GL P P P P P A+ P+ A PS Sbjct: 1147 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1206 Query: 223 GGLQRPASRSLSSSATPLSSP-----ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-- 275 GGL P+ + + TP ++P + PS +G P PA + P PKG A PP+ Sbjct: 1207 GGLATPSPK--GAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGPATPPPKGA 1263 Query: 276 ---------------VTPPRKDA---------APALGPLSSSPLATPSPSA--PPSPSAP 309 TPP K A +P GP +S P P+P A PPSP Sbjct: 1264 PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGS 1323 Query: 310 PSL---QTLPSPPA-TPPSQATTSLGSPTLQATHSFL---PSPPLSPLATPPPQAPPALA 362 P + P+PPA TPPS G+PTL AT P+ P S PP A P+ Sbjct: 1324 PGTPPPKGAPTPPAVTPPSPK----GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHK 1379 Query: 363 LPPLQAPPSP------------PASP---PLSPLATPSPQAPNALAVHLLQAPFSPPPSP 407 P PPSP P SP PLSP P+ A + +PP Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439 Query: 408 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP--PPQAPPP 465 PV +P S P ATP S+ P+L A P PPA ++ S++P P P P Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499 Query: 466 LAAPPLQLAKP--PPQAPPALATPPLQALP-SPPASFPGQAPFSPSASLPMSPLATPPPQ 522 + AP L P P + P ATP + P +P A+ + +P+ P L P Sbjct: 1500 MGAPTLPAVIPSSPKEVP---ATPSSRRDPIAPTATLLSKK--TPATLAPKEALIPPAMT 1554 Query: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL------APGP---P 573 P P + P PA+P+ + PP P T P L +P P P Sbjct: 1555 VPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAP 1614 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS 633 PP+ +P S GP + TS P P A+ + ++ A P A Sbjct: 1615 TPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVT----CKMGATVPQASK 1670 Query: 634 RGPAP--PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE----SATPAPGALDPGP 687 PA P A + AP P + + T +GP+ SAT P DP Sbjct: 1671 GLPAKKGPTALKEVLVAPAP--------ESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722 Query: 688 SPGTSG 693 G+ G Sbjct: 1723 KNGSKG 1728 Score = 194 bits (494), Expect = 2e-49 Identities = 189/674 (28%), Positives = 255/674 (37%), Gaps = 65/674 (9%) Query: 13 AARTPAARAP----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIG 66 A TPAA P GL TP P G+P P P+ L G P A G Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230 Query: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS--PGRASGTTRPGPLGQKG 124 G P +P+ PT + P S +G A P +P P ++ P G P G Sbjct: 1231 GLATP--SPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288 Query: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184 + + G AT PK + A + +PGTP P + A T + P+ Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPP------KGAPTPPAVTPPS 1342 Query: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR----SLSSSATPL 240 P P P P + S P+P A GG P S ++ S Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDP 1402 Query: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS- 299 +SPA S + P P L PP VTP APA P ATPS Sbjct: 1403 TSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP-ATPSS 1461 Query: 300 ----------PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349 P +P P AP + T SP P + A +G+PTL A +PS P Sbjct: 1462 KGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP--MGAPTLPAV---IPSSPKEV 1516 Query: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409 ATP + P L + +P P L P+ P+ + P P +P Sbjct: 1517 PATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSS 1576 Query: 410 QAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP 469 + SPPA V+PS + +P L PP PSP + P P+ TPP P Sbjct: 1577 KEASSPPA---VTPSTYKGAPSPKELLIPPAVTSPSPKEA-PTPPAVTPPSPEKGPATPA 1632 Query: 470 PLQLAKPPPQAPPAL---ATPPLQALPSPPASFPGQAPFSPSASLPMS---PLATPPPQA 523 P PP P +L T P A+ P + P+ P + L P P++ Sbjct: 1633 PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPES 1692 Query: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 P++ AP + P + +S T +P P P GP T +AP P P + S T Sbjct: 1693 TPIITAPTRKGPQTKKSSAT--SPPICPDPSAKNGSKGPLST--VAPAPLLPVQKDSSKT 1748 Query: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAA---ASPPPDAELAACHPAAWSRGPAPPL 640 G D A HS P E + S P AA P P++ A+ S P+PP+ Sbjct: 1749 AKGKD-ASHSPKGPLAPPESKA--STPLTAAAFEKVLPKPES-------ASVSAAPSPPV 1798 Query: 641 AFRGAPGAPLPWPP 654 + AP +P+P P Sbjct: 1799 SLPLAP-SPVPTLP 1811 Score = 179 bits (455), Expect = 7e-45 Identities = 216/719 (30%), Positives = 272/719 (37%), Gaps = 111/719 (15%) Query: 72 ESAPRAGPT--RTSRPPASGRGERAPPAKNT--SPGPVSSPGRASGTTRPGPLGQKGLRI 127 ++AP+ P+ TS P A AK + P P+ P AS T P + I Sbjct: 564 QAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP--ASSMTSPLGVNSSASVI 621 Query: 128 SAEETVARGKATEAPKRSALSAGARR------DTSGPTPGTPSPAMARRSRAAGTEVGLP 181 + A K S ++ D +G P T + A+ G Sbjct: 622 KTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTV 681 Query: 182 RPAPSARP-RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 AP P + T V +ASE+ PSP P A + + P Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLA---------TLVLAPEIPK 732 Query: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQ---ALRPPQVTP---PRKDAAPALGPLSSSP 294 S P+ S P A GTP P K G+ AL P +P P +D+ + S Sbjct: 733 SVPSPSLPPA-GTP-----PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGT 786 Query: 295 LA----TPSP---SAPPSPSAPPSLQTLPSP---------PATP------PSQATTSLGS 332 L +PSP S P PP+ + P P +P P + + GS Sbjct: 787 LTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGS 846 Query: 333 PTLQAT-HSFLPSPPLSPLATPPPQA-----PPALALPPLQAP-PSPPASP-PLSPLATP 384 AT HS P+PP SP P P A P + LPP + P PS P P ATP Sbjct: 847 KDSPATTHS--PTPP-SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903 Query: 385 SPQAPNALAV--------HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436 +P+ AL++ AP P SP + +PPA+ P SP P + +P Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963 Query: 437 APPLQVPPSPPASPPMSPSATPPPQ-AP-PPLAAPPLQLAKPPPQAPPALATPPLQALPS 494 PP PPSP P ATP P+ AP PP A PP P +P TPP PS Sbjct: 964 TPPAATPPSPKGGP-----ATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPS 1018 Query: 495 PPASFPGQAPFSPSASLPM---------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 545 P S P PF AS P SP ATP P+ P A L P PA+P+L+ Sbjct: 1019 PKGS-PAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLK 1077 Query: 546 APRRPPTPGPDTSVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR 604 PP P + GP AP PP SP L+ P G ++ +TP Sbjct: 1078 GAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP---- 1133 Query: 605 GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664 P+GG A PP A PAA P LA GAP P AT P GL Sbjct: 1134 ---PSPKGGLATPPPKGAPTT---PAATPPSPKGGLATPPPKGAPTT-PAATPPSPKGGL 1186 Query: 665 CTIYETEGPESATPAPGALDPGPSPG--TSGGKAAAGAGAGASSRSPKQARLGELPLGA 721 T P+ A P A P P G T K A A A+ SPK P GA Sbjct: 1187 A----TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA-ATPPSPKGGLATPSPKGA 1240 Score = 142 bits (357), Expect = 2e-33 Identities = 188/674 (27%), Positives = 256/674 (37%), Gaps = 136/674 (20%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 K A TP + G T P G+P PP P+ G+ G P G Sbjct: 1284 KGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPS------PKGSPGTPP---PKGAPT 1334 Query: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126 + +P+ PT + P+S G P +K P ++P G P ++G Sbjct: 1335 PPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394 Query: 127 ISAEETVARGKAT--EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-P 183 I + + A +PK++ + R + P+ G +P A T V L + P Sbjct: 1395 IPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTP-------PAVTPVSLKKAP 1447 Query: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 A SA P GP A+ S +P+ A PS + PA + +++S++P +P Sbjct: 1448 ATSA----PKGGP------ATPSSKGDPTLPAVTPPSP---KEPPAPKQVATSSSPKKAP 1494 Query: 244 ARSGPSARGTPRAPA-HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS- 301 A P+ G P PA PS PK P + R AP LS AT +P Sbjct: 1495 AT--PAPMGAPTLPAVIPSSPKEV------PATPSSRRDPIAPTATLLSKKTPATLAPKE 1546 Query: 302 -------APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP---LSPLA 351 PSP P++ T PATP S+ +S + T +T+ PSP + P Sbjct: 1547 ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVT-PSTYKGAPSPKELLIPPAV 1605 Query: 352 TPPPQAPPALALPPLQAPPSP---PASP-----PLSPLATPS------------------ 385 T P +P PP PPSP PA+P P SP TPS Sbjct: 1606 TSP--SPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGA 1663 Query: 386 --PQAPNALAV--------HLLQAPFSPPPSPPVQAPF--------SPPASPPV--SPSA 425 PQA L +L AP +P +P + AP S SPP+ PSA Sbjct: 1664 TVPQASKGLPAKKGPTALKEVLVAP-APESTPIITAPTRKGPQTKKSSATSPPICPDPSA 1722 Query: 426 TPPSQAPPSLAAP----PLQVPPSPPAS------PPMSPSATPPPQAPPPLAAPPLQLAK 475 S+ P S AP P+Q S A P P A P +A PL A + Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVL 1782 Query: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP--LLQ 533 P P+ + + A PSPP S P L SP+ T PP+ + ++P +L+ Sbjct: 1783 PKPE------SASVSAAPSPPVSLP----------LAPSPVPTLPPKQQFLPSSPGLVLE 1826 Query: 534 VPPSP--PASPTLQAPRRPPTP----GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 587 P P PA P PP P P SV T A P P PS T + Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK 1886 Query: 588 DLAGHSSSATSTPE 601 S S S PE Sbjct: 1887 GSGTESDSDESVPE 1900 Score = 105 bits (263), Expect = 1e-22 Identities = 194/800 (24%), Positives = 281/800 (35%), Gaps = 139/800 (17%) Query: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 A + +T + P + P P G+P PP V+ + P+A G+ A+ Sbjct: 180 APSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCV--------TPMASIQSGV--AS 229 Query: 70 IPESAPR-----AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124 +P++ P A P +S P + GPVS P S +T+ P+ Sbjct: 230 LPQTTPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSS 289 Query: 125 LRISAEET-----VARGKATEAPKRSALSAGARRDTSGPT----PGTPSPAMARRSRAAG 175 + + T ++ G +S+ + +GP+ P + ++ S A Sbjct: 290 QKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGAS 349 Query: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235 PS R P R V A+ + +P+ + PS + S SL + Sbjct: 350 --------YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSL-N 400 Query: 236 SATPLSSPARSGPSARGTPRAPAHPS--QPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 AT S + + +P A H P P VT P AA + Sbjct: 401 VATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVA 460 Query: 294 PLATPSPSAPP----SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP---- 345 +P S+ P P++P +L P P P +Q T+L P LP P Sbjct: 461 TCVSPPMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPP----LPDPEDLK 516 Query: 346 --PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP 403 P S L P Q LQ P+ P SP + + L+QA +P Sbjct: 517 NLPSSVLVKFPTQ-------KDLQTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQA--AP 567 Query: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP-PLQVPPSPPASP---PMSPSATPP 459 SP Q+ S P P+SP AT A SL P P+ P S SP S S Sbjct: 568 KNSPSFQSTSSSP-EIPLSPEAT---LAKKSLGEPLPIGKPASSMTSPLGVNSSASVIKT 623 Query: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519 P +A PL +L TP + A P A G AP + + + A+P Sbjct: 624 DSYAGPDSAGPL--------LKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASP 675 Query: 520 --------PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 P+ PV L +P P AS P P P + + P TL LAP Sbjct: 676 FLEGTVSLAPKNHPVKEGTLTTLPLVPTASENC-----PVAPSPQNTCA-PLATLVLAPE 729 Query: 572 PP---PPPSRSPSSTLSGP---DLAGHSSS---ATSTPEELRGYDSGPEGGAAAS----- 617 P P PS P+ T G D H+S+ S+P+E DSG A++ Sbjct: 730 IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTY 789 Query: 618 ------------------PP-------PDAEL----AACHPAAWSRGPAPPLAFRGAPGA 648 PP PD + + P S P L+F+G+ + Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDS 849 Query: 649 PL----PWPPATGPGSADGLCTIYETEG---PESATPAPGALD-PGPSPGTSGGKAAAGA 700 P P PP+ T +G P TP P ++ P P G + Sbjct: 850 PATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAP 909 Query: 701 GAGASSRSPKQARLGELPLG 720 +S SPK+AR P G Sbjct: 910 ALSMTSSSPKKARATPAPKG 929 Score = 87.0 bits (214), Expect = 6e-17 Identities = 159/638 (24%), Positives = 231/638 (36%), Gaps = 131/638 (20%) Query: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 201 P SALS A GPT P ++ + P P+PS P E P S Sbjct: 27 PMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSS 86 Query: 202 SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261 S T P A P+ L P +S +A L+SP P+ +GTP + A Sbjct: 87 S----GTALPLGTAPEAPTFLPNLIGP---PISPAALALASP-MIAPTLKGTPSSSA--- 135 Query: 262 QPKPKGLQALRPPQVT-----PPRKDAAPALGPL--SSSPLATPSPSAPPSP-------- 306 P L AL P V PP +P + S S + +P AP P Sbjct: 136 ---PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP 192 Query: 307 -SAPPSLQTLPSPP---ATPPSQATTSLGSPTLQATHSFLP-SPPLSPLATPPPQ----- 356 P+ + PSPP +T P T + S +Q+ + LP + P + LA PQ Sbjct: 193 SEVVPNPKGTPSPPCIVSTVPYHCVTPMAS--IQSGVASLPQTTPTTTLAIASPQVKDTT 250 Query: 357 ------APPALALPPLQAPPSPPASPPLS----PLATPS---------PQAPNALAVHLL 397 +P L+ P SPPA+ LS P+ T S P P +L HL Sbjct: 251 ISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLA 310 Query: 398 ---QAPF--------------SPPPSPPVQAPFSPP-ASPPVSPSATPP-----SQAPPS 434 Q+ F S P + S AS P S PP P + Sbjct: 311 PLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPAT 370 Query: 435 LAAPPLQVP-----PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAP---PALAT 486 +AA P+ P PS +S SPS + L+ + K P A P +A Sbjct: 371 VAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQ 430 Query: 487 PPLQALPSPP--ASFPGQAPFSPSASLPMSPLATPPPQAPPV-----------LAAPLLQ 533 P+ ++ + P + P +P+ + ++ +PP + P+ + AP+ Sbjct: 431 MPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAPVAP 490 Query: 534 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP-------------GPPPPPSRSP 580 PS + TL+ P PP P P+ + P L P G P P+++ Sbjct: 491 KEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSPAQAG 550 Query: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640 +T P + +A + S PE P+A L A S G P+ Sbjct: 551 LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE----IPLSPEATL-----AKKSLGEPLPI 601 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678 G P + + P G S+ + GP+SA P Sbjct: 602 ---GKPASSMTSP--LGVNSSASVIKTDSYAGPDSAGP 634 Score = 79.3 bits (194), Expect = 1e-14 Identities = 103/370 (27%), Positives = 145/370 (39%), Gaps = 47/370 (12%) Query: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366 + P + Q LP P A +S S T P P L P +P PQ P A Sbjct: 8 TVPATEQELPQPQAETAVLPMSSALSVTAALGQ---PGPTLPPPCSPAPQQCPLSAAN-- 62 Query: 367 QAPPSP-PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPS 424 QA P P P++ +PL P PQ+ + A+ L AP +P P + P SP A SP Sbjct: 63 QASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM 122 Query: 425 ATPPSQAPPSLAAPPLQV---PPSPPASPPMSPS-ATPPPQAPPPLAAPPLQLAKP-PPQ 479 P + PS +AP V P S S P+ T PP + + L+ P P Sbjct: 123 IAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAPS 182 Query: 480 AP-------PALATPPLQALPSPPASFPGQAPF---SPSASL-----------PMSPLAT 518 P P+ P + PSPP P+ +P AS+ P + LA Sbjct: 183 EPKTNLNKVPSEVVPNPKGTPSPPC-IVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI 241 Query: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 PQ + +L + P P S +L+ P PP ++ S P +T + P P Sbjct: 242 ASPQVKDTTISSVL-ISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300 Query: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA- 637 P S G LA S+ + + L G G +A S P ++ H + + P+ Sbjct: 301 FPISL--GSHLAPLHQSSFGSVQLL-----GQTGPSALSDPTVKTISVDHSSTGASYPSQ 353 Query: 638 ----PPLAFR 643 PPL R Sbjct: 354 RSVIPPLPSR 363 >gi|116284392 mucin 2 precursor [Homo sapiens] Length = 5179 Score = 162 bits (410), Expect = 1e-39 Identities = 133/436 (30%), Positives = 170/436 (38%), Gaps = 65/436 (14%) Query: 155 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 214 T P TPSP + T P + P PPT P +++ TT P P Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTP-PPTTTPSPPITT-----TTTPPPT 1451 Query: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP 274 P P S + + T SP + PS T +P + P PP Sbjct: 1452 TTPSP--------PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP-------PP 1496 Query: 275 QVTPPRKDAAPALGPLSSS---PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG 331 TP P P S++ P TPSP + + PP+ T PSPP T P TS Sbjct: 1497 TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPT--TTPSPPTTTPITPPTS-- 1552 Query: 332 SPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA 391 + TL T + PSPP + TPPP P+ PP PSPP +P T +P P Sbjct: 1553 TTTLPPTTT--PSPPPTTTTTPPPTTTPS---PPTTTTPSPPTITTTTPPPTTTPSPPTT 1607 Query: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA--- 448 P + PSPP P +PP S P T PS P + PP PSPP Sbjct: 1608 TTT---TPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1664 Query: 449 -SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507 SPP++ + TPPP P + P+ PP + TP PS P + Sbjct: 1665 PSPPITTTTTPPPTTTP---SSPITTTPSPPTT--TMTTPSPTTTPSSPIT--------- 1710 Query: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567 + + P S PP P + P PSPP + T P T+ S P T Sbjct: 1711 TTTTPSSTTTPSPP--PTTMTTPSPTTTPSPPTTTM--------TTLPPTTTSSPLTTTP 1760 Query: 568 LAPGPPPPPSRSPSST 583 L P PP+ SP ST Sbjct: 1761 LPPS-ITPPTFSPFST 1775 Score = 157 bits (398), Expect = 3e-38 Identities = 128/439 (29%), Positives = 168/439 (38%), Gaps = 58/439 (13%) Query: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLP------RPAPSARPRPP 192 T P + S T+ P TPSP + + T P P P+ P PP Sbjct: 1414 TTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPP 1473 Query: 193 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 252 T P ++ S +TT +P PS + TP++ PA Sbjct: 1474 TTTPSPPTTTPSPPTTTTTTPPPTTTPS-------------PPTTTPITPPA-------S 1513 Query: 253 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-ATPSPSAPPSPSAPPS 311 T P + P PP TP P P S++ L T +PS PP+ + P Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPP 1573 Query: 312 LQTLPSPP-ATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 T PSPP T PS T + +P T PSPP + TPPP P+ PP P Sbjct: 1574 PTTTPSPPTTTTPSPPTITTTTPPPTTT----PSPPTTTTTTPPPTTTPS---PPTTTPI 1626 Query: 371 SPPAS-PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPS 429 +PP S L P TPSP +PPP+ P + SPP++ + TPP Sbjct: 1627 TPPTSTTTLPPTTTPSPPPTTTT---------TPPPTTTPSPPTTTTPSPPITTTTTPPP 1677 Query: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489 PS P+ PSPP + +PS T P +P P P P P + TP Sbjct: 1678 TTTPS---SPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSP-PPTTMTTPSP 1733 Query: 490 QALPSPP----ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 545 PSPP + P SP + P+ P TPP +P P P P + T Sbjct: 1734 TTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTP--TTPCVPLCNWTGW 1791 Query: 546 APRRPPT---PGPDTSVSG 561 P PG DT + G Sbjct: 1792 LDSGKPNFHKPGGDTELIG 1810 Score = 157 bits (397), Expect = 4e-38 Identities = 145/512 (28%), Positives = 191/512 (37%), Gaps = 73/512 (14%) Query: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287 P + +++ + P ++P S P T P + P P PP T P + P Sbjct: 1391 PMDKCITTPSPPTTTP--SPPPTSTTTLPPT--TTPSPPTTTTTTPPPTTTP---SPPIT 1443 Query: 288 GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH---SFLPS 344 + P TPSP + + PP+ T PSPP T PS TT+ PT T + PS Sbjct: 1444 TTTTPPPTTTPSPPISTTTTPPPT--TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPS 1501 Query: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 PP + TPP LPP P SPP + +P P + Sbjct: 1502 PPTTTPITPPASTT---TLPPTTTP-SPPTTTTTTP-------------------PPTTT 1538 Query: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA----SPPMSPSATPPP 460 PSPP P +PP S P T PS P + PP PSPP SPP + TPPP Sbjct: 1539 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPP 1598 Query: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520 P +PP PP P +PP +PP S P + + S P + TPP Sbjct: 1599 TTTP---SPPTTTTTTPP--PTTTPSPPTTTPITPPTSTTTLPP-TTTPSPPPTTTTTPP 1652 Query: 521 PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580 P P +P PSPP + T P P T+ P T P P PS SP Sbjct: 1653 PTTTP---SPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPS-SP 1708 Query: 581 SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640 +T + P S+T+TP + P SPP P Sbjct: 1709 ITTTTTP-------SSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTL------------PP 1749 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP----SPGTSGGKA 696 +P P PP+ P + T T G LD G PG Sbjct: 1750 TTTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELI 1809 Query: 697 AAGAGAG-ASSRSPKQARLGELPLGALQASVV 727 G G A++ S + ++P+G L +VV Sbjct: 1810 GDVCGPGWAANISCRATMYPDVPIGQLGQTVV 1841 Score = 137 bits (345), Expect = 4e-32 Identities = 115/446 (25%), Positives = 163/446 (36%), Gaps = 66/446 (14%) Query: 24 LLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83 + TP PP + PPP + T+P + + PT T+ Sbjct: 1396 ITTPSPPTTTPSPPPTSTT--------------------------TLPPTTTPSPPTTTT 1429 Query: 84 RPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK 143 P P T+P P ++P TT P T + T +P Sbjct: 1430 TTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP---------PTTTPSPPTTTPSPP 1480 Query: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203 + S T+ P TPSP + LP P+ P PPT Sbjct: 1481 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLP---PTTTPSPPTT--------- 1528 Query: 204 SEHSTTEPSPAARRRPSAGGGLQRPAS-RSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 262 +TT P P P + P S +L + TP P + T +P + Sbjct: 1529 ---TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585 Query: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP--SPPA 320 P P + PP T P + P + P TPSP + P S TLP + P+ Sbjct: 1586 PSPPTITTTTPPPTTTP---SPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPS 1642 Query: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP 380 PP+ TT + T + PSPP++ TPPP P+ P+ PSPP + +P Sbjct: 1643 PPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPS---SPITTTPSPPTTTMTTP 1699 Query: 381 LATPSPQAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 439 T +P +P + P S PSPP +P + SP T + PP+ + P Sbjct: 1700 SPTTTPSSP----ITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSP 1755 Query: 440 LQVPPSPPA--SPPMSPSATPPPQAP 463 L P PP+ P SP +T P P Sbjct: 1756 LTTTPLPPSITPPTFSPFSTTTPTTP 1781 Score = 104 bits (259), Expect = 4e-22 Identities = 143/717 (19%), Positives = 232/717 (32%), Gaps = 76/717 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3695 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3754 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3755 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3808 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3809 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3865 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3866 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3920 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3921 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3978 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3979 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 4037 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 4038 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 4097 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 4098 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4157 Query: 529 APLLQVPPSPPAS------PTLQAPRRPPTPGPDTSVSGPRLTLALAP------GPPPPP 576 + P+P + P PTP P + +GP + AP PPP Sbjct: 4158 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPE 4217 Query: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636 S +P ++ S S++ ST P ++ PP A + Sbjct: 4218 SSTPQTSRSTSSPLTESTTLLST--------LPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269 Query: 637 APPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSG 693 PP PG P TG SA T+ +T + TP P L T+G Sbjct: 4270 PPPSTTTSPPGTPTR-GTTTGSSSAPTPSTV-QTTTTSAWTPTPTPLSTPSIIRTTG 4324 Score = 98.2 bits (243), Expect = 3e-20 Identities = 99/391 (25%), Positives = 139/391 (35%), Gaps = 53/391 (13%) Query: 16 TPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73 T P TP PP + PPP TP+ P++ T P + Sbjct: 1427 TTTTTPPPTTTPSPPITTTTTPPPTTTPSP-------------PISTTT------TPPPT 1467 Query: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133 + PT T PP + P T+P P ++P + T P L + + Sbjct: 1468 TTPSPPTTTPSPPTTTPSP--PTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525 Query: 134 ARGKATEAPKRSALSAGARRDTSGPT-----PGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 T P + S + PT P T +P+ + P P + Sbjct: 1526 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTT 1585 Query: 189 PRPPT----EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS-LSSSATPLSSP 243 P PPT P + S +TT P P P + P S + L + TP P Sbjct: 1586 PSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPP 1645 Query: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS---PLATPSP 300 + T +P + P P PP T P P +++ P T +P Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP 1705 Query: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA 360 S+P + + PS T PSPP P+ TT SPT PSPP + + T PP Sbjct: 1706 SSPITTTTTPSSTTTPSPP---PTTMTTP--SPTT------TPSPPTTTMTT----LPPT 1750 Query: 361 LALPPLQAPPSPPA--SPPLSPLATPSPQAP 389 PL P PP+ P SP +T +P P Sbjct: 1751 TTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781 Score = 94.4 bits (233), Expect = 4e-19 Identities = 144/759 (18%), Positives = 236/759 (31%), Gaps = 89/759 (11%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3557 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3616 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3617 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3670 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3671 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3727 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3728 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3782 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3783 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3840 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3841 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3899 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3900 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3959 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 4019 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 4020 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4079 Query: 579 SPSST----------------LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA 622 +P++T P +++ T TP P G + P Sbjct: 4080 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPIT 4133 Query: 623 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 682 P G P + P T G+ T T + TP P Sbjct: 4134 TTTTVTPTPTPTGTQTPTTTPITTTTTVT-PTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4192 Query: 683 LDPGPSPGTSGGKAA--AGAGAGASSRSPKQARLGELPL 719 GP TS A + S +P+ +R PL Sbjct: 4193 TQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL 4231 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 1910 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1969 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 1970 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2029 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2030 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2083 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2084 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2140 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2141 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2195 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2196 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2253 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2254 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2312 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2313 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2372 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2432 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2433 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2492 Query: 579 SPSST 583 +P++T Sbjct: 2493 TPTTT 2497 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 1933 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 1992 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 1993 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2052 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2053 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2106 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2107 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2163 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2164 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2218 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2219 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2276 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2335 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2336 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2395 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2396 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2455 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2456 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2515 Query: 579 SPSST 583 +P++T Sbjct: 2516 TPTTT 2520 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2075 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2076 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2129 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2130 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2186 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2187 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2241 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2242 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2299 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2300 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2358 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2359 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2418 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2419 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2478 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2479 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2538 Query: 579 SPSST 583 +P++T Sbjct: 2539 TPTTT 2543 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2038 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2039 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2098 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2099 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2152 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2153 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2209 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2210 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2264 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2265 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2322 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2323 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2381 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2382 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2441 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2501 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2502 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2561 Query: 579 SPSST 583 +P++T Sbjct: 2562 TPTTT 2566 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2121 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2122 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2175 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2176 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2232 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2233 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2287 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2288 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2345 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2346 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2404 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2405 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2464 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2465 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2524 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2525 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2584 Query: 579 SPSST 583 +P++T Sbjct: 2585 TPTTT 2589 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2025 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2084 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2085 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2144 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2145 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2198 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2199 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2255 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2256 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2310 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2311 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2368 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2369 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2427 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2428 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2487 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2488 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2547 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2548 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2607 Query: 579 SPSST 583 +P++T Sbjct: 2608 TPTTT 2612 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2108 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2167 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2168 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2221 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2222 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2278 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2279 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2333 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2334 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2391 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2392 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2450 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2451 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2510 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2570 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2571 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2630 Query: 579 SPSST 583 +P++T Sbjct: 2631 TPTTT 2635 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2130 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2131 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2190 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2191 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2244 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2245 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2301 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2302 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2356 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2357 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2414 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2415 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2473 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2474 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2533 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2534 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2593 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2594 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2653 Query: 579 SPSST 583 +P++T Sbjct: 2654 TPTTT 2658 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2153 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2154 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2213 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2214 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2267 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2268 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2324 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2325 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2379 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2380 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2437 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2438 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2496 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2497 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2556 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2557 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2616 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2617 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2676 Query: 579 SPSST 583 +P++T Sbjct: 2677 TPTTT 2681 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2176 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2177 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2236 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2237 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2290 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2291 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2347 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2348 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2402 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2403 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2460 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2461 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2519 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2520 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2579 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2639 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2640 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2699 Query: 579 SPSST 583 +P++T Sbjct: 2700 TPTTT 2704 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2200 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2259 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2260 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2313 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2314 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2370 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2371 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2425 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2426 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2483 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2484 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2542 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2543 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2602 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2603 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2662 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2663 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2722 Query: 579 SPSST 583 +P++T Sbjct: 2723 TPTTT 2727 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2282 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2283 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2337 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2393 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2394 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2448 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2449 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2506 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2507 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2565 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2566 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2625 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2626 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2685 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2686 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2745 Query: 579 SPSST 583 +P++T Sbjct: 2746 TPTTT 2750 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2246 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2305 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2306 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2359 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2360 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2416 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2417 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2471 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2472 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2529 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2530 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2588 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2589 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2648 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2708 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2709 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2768 Query: 579 SPSST 583 +P++T Sbjct: 2769 TPTTT 2773 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2269 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2328 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2329 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2383 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2439 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2440 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2494 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2495 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2552 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2553 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2611 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2612 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2671 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2672 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2731 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2732 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2791 Query: 579 SPSST 583 +P++T Sbjct: 2792 TPTTT 2796 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2351 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2352 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2405 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2406 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2462 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2463 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2517 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2518 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2575 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2576 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2634 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2635 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2694 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2695 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2754 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2755 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2814 Query: 579 SPSST 583 +P++T Sbjct: 2815 TPTTT 2819 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2375 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2428 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2429 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2485 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2486 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2540 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2541 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2598 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2599 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2657 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2658 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2717 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2777 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2778 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2837 Query: 579 SPSST 583 +P++T Sbjct: 2838 TPTTT 2842 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2397 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2398 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2452 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2508 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2509 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2563 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2564 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2621 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2622 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2680 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2681 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2740 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2741 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2800 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2801 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2860 Query: 579 SPSST 583 +P++T Sbjct: 2861 TPTTT 2865 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2361 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2420 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2421 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2474 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2475 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2531 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2532 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2586 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2587 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2644 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2645 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2703 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2704 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2764 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2823 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2824 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2883 Query: 579 SPSST 583 +P++T Sbjct: 2884 TPTTT 2888 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2384 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2443 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2444 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2497 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2498 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2554 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2555 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2609 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2610 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2667 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2668 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2726 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2727 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2786 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2846 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2847 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2906 Query: 579 SPSST 583 +P++T Sbjct: 2907 TPTTT 2911 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2466 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2467 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2520 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2521 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2577 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2578 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2632 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2633 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2690 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2691 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2749 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2750 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2809 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2810 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2869 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2870 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2929 Query: 579 SPSST 583 +P++T Sbjct: 2930 TPTTT 2934 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2430 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2489 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2490 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2543 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2544 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2600 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2601 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2655 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2713 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2714 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2772 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2773 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2832 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2833 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2892 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2893 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2952 Query: 579 SPSST 583 +P++T Sbjct: 2953 TPTTT 2957 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2453 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2512 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2513 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2566 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2567 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2623 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2624 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2678 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2679 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2736 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2737 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2795 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2796 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2855 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2915 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2916 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2975 Query: 579 SPSST 583 +P++T Sbjct: 2976 TPTTT 2980 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2535 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2536 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2589 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2590 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2646 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2647 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2701 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2702 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2759 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2760 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2818 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2819 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2878 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2879 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2938 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2939 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2998 Query: 579 SPSST 583 +P++T Sbjct: 2999 TPTTT 3003 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2499 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2558 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2559 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2612 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2613 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2669 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2670 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2724 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2725 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2782 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2783 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2841 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2842 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2901 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2902 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2961 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2962 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3021 Query: 579 SPSST 583 +P++T Sbjct: 3022 TPTTT 3026 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2522 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2581 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2582 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2635 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2636 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2692 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2693 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2747 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2805 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2806 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2864 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2865 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2924 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 2984 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 2985 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3044 Query: 579 SPSST 583 +P++T Sbjct: 3045 TPTTT 3049 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2604 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2605 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2658 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2659 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2715 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2716 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2770 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2771 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2828 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2829 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2887 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2888 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2947 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2948 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3007 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3008 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3067 Query: 579 SPSST 583 +P++T Sbjct: 3068 TPTTT 3072 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2568 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2627 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2628 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2681 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2682 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2738 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2739 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2793 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2794 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2851 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2852 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2910 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2911 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2970 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2971 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3030 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3031 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3090 Query: 579 SPSST 583 +P++T Sbjct: 3091 TPTTT 3095 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2591 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2650 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2651 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2704 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2705 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2761 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2762 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2816 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2817 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2874 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2875 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2933 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2934 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2993 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3053 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3054 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3113 Query: 579 SPSST 583 +P++T Sbjct: 3114 TPTTT 3118 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2673 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2674 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2727 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2728 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2784 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2785 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2839 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2840 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2897 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2898 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2956 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2957 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3016 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3017 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3076 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3077 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3136 Query: 579 SPSST 583 +P++T Sbjct: 3137 TPTTT 3141 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2637 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2696 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2697 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2750 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2751 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2807 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2808 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2862 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2863 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2920 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2921 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 2979 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 2980 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3039 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3040 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3099 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3100 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3159 Query: 579 SPSST 583 +P++T Sbjct: 3160 TPTTT 3164 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2660 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2719 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2720 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2773 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2774 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2830 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2831 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2885 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2886 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2943 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2944 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3002 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3003 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3062 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3122 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3123 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3182 Query: 579 SPSST 583 +P++T Sbjct: 3183 TPTTT 3187 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2742 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2743 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2796 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2797 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2853 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2854 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2908 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2909 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2966 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2967 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3025 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3026 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3085 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3086 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3145 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3146 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3205 Query: 579 SPSST 583 +P++T Sbjct: 3206 TPTTT 3210 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2706 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2765 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2766 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2819 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2820 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2876 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2877 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2931 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2932 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 2989 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 2990 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3048 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3049 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3108 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3109 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3168 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3169 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3228 Query: 579 SPSST 583 +P++T Sbjct: 3229 TPTTT 3233 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2729 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2788 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2789 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2842 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2843 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2899 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2900 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2954 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2955 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3012 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3013 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3071 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3072 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3131 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3191 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3192 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3251 Query: 579 SPSST 583 +P++T Sbjct: 3252 TPTTT 3256 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2811 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2812 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2865 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2866 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2922 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2923 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 2977 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 2978 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3035 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3036 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3094 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3095 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3154 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3155 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3214 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3215 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3274 Query: 579 SPSST 583 +P++T Sbjct: 3275 TPTTT 3279 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2775 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2834 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2835 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2888 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2889 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2945 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2946 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3000 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3001 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3058 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3059 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3117 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3118 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3177 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3178 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3237 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3238 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3297 Query: 579 SPSST 583 +P++T Sbjct: 3298 TPTTT 3302 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2798 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2857 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2858 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2911 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2912 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2968 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2969 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3023 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3024 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3081 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3082 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3140 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3141 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3200 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3260 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3261 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3320 Query: 579 SPSST 583 +P++T Sbjct: 3321 TPTTT 3325 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2880 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2881 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2934 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2935 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 2991 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 2992 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3046 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3047 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3104 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3105 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3163 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3164 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3223 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3224 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3283 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3284 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3343 Query: 579 SPSST 583 +P++T Sbjct: 3344 TPTTT 3348 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2844 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2903 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2904 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2957 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2958 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3014 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3015 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3069 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3070 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3127 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3128 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3186 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3187 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3246 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3247 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3306 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3307 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3366 Query: 579 SPSST 583 +P++T Sbjct: 3367 TPTTT 3371 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2867 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2926 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2927 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2980 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 2981 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3037 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3038 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3092 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3093 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3150 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3151 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3209 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3210 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3269 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3329 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3330 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3389 Query: 579 SPSST 583 +P++T Sbjct: 3390 TPTTT 3394 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2949 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2950 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3003 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3004 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3060 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3061 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3115 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3116 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3173 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3174 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3232 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3233 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3293 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3352 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3353 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3412 Query: 579 SPSST 583 +P++T Sbjct: 3413 TPTTT 3417 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2913 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2972 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2973 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3026 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3027 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3083 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3084 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3138 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3139 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3196 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3197 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3255 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3256 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3315 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3316 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3375 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3376 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3435 Query: 579 SPSST 583 +P++T Sbjct: 3436 TPTTT 3440 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2936 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2995 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 2996 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3049 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3050 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3106 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3107 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3161 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3162 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3219 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3220 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3278 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3279 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3338 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3398 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3399 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3458 Query: 579 SPSST 583 +P++T Sbjct: 3459 TPTTT 3463 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3018 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3019 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3072 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3073 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3129 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3130 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3184 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3242 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3243 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3301 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3302 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3361 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3362 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3421 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3422 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3481 Query: 579 SPSST 583 +P++T Sbjct: 3482 TPTTT 3486 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 2982 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3041 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3042 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3095 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3096 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3152 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3153 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3207 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3208 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3265 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3266 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3324 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3325 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3384 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3385 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3444 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3445 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3504 Query: 579 SPSST 583 +P++T Sbjct: 3505 TPTTT 3509 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3005 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3064 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3065 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3118 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3119 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3175 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3176 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3230 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3231 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3288 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3289 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3347 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3348 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3407 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3467 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3468 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3527 Query: 579 SPSST 583 +P++T Sbjct: 3528 TPTTT 3532 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3087 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3088 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3141 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3142 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3198 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3199 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3253 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3254 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3311 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3312 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3370 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3371 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3430 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3431 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3490 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3491 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3550 Query: 579 SPSST 583 +P++T Sbjct: 3551 TPTTT 3555 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3051 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3110 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3111 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3164 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3165 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3221 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3222 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3276 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3334 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3335 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3393 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3394 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3453 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3454 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3513 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3514 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3573 Query: 579 SPSST 583 +P++T Sbjct: 3574 TPTTT 3578 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3074 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3133 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3134 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3187 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3188 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3244 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3245 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3299 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3300 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3357 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3358 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3416 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3417 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3476 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3536 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3537 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3596 Query: 579 SPSST 583 +P++T Sbjct: 3597 TPTTT 3601 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3156 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3157 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3210 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3211 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3267 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3268 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3322 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3323 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3380 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3381 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3439 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3440 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3499 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3500 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3559 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3560 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3619 Query: 579 SPSST 583 +P++T Sbjct: 3620 TPTTT 3624 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3120 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3179 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3180 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3233 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3234 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3290 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3291 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3345 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3346 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3403 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3404 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3462 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3463 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3522 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3523 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3582 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3583 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3642 Query: 579 SPSST 583 +P++T Sbjct: 3643 TPTTT 3647 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3143 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3202 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3203 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3256 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3257 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3313 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3314 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3368 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3369 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3426 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3427 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3485 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3486 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3545 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3605 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3606 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3665 Query: 579 SPSST 583 +P++T Sbjct: 3666 TPTTT 3670 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3166 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3225 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3226 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3279 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3280 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3336 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3337 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3391 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3392 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3449 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3450 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3508 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3509 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3568 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3569 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3628 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3629 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3688 Query: 579 SPSST 583 +P++T Sbjct: 3689 TPTTT 3693 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3189 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3248 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3249 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3302 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3303 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3359 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3360 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3414 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3415 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3472 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3473 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3531 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3532 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3591 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3592 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3651 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3652 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3711 Query: 579 SPSST 583 +P++T Sbjct: 3712 TPTTT 3716 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3212 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3271 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3272 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3325 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3326 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3382 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3383 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3437 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3438 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3495 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3496 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3554 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3555 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3614 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3674 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3675 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3734 Query: 579 SPSST 583 +P++T Sbjct: 3735 TPTTT 3739 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3294 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3295 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3348 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3349 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3405 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3406 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3460 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3461 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3518 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3519 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3577 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3578 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3637 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3638 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3697 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3698 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3757 Query: 579 SPSST 583 +P++T Sbjct: 3758 TPTTT 3762 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3258 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3317 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3318 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3371 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3372 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3428 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3429 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3483 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3484 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3541 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3542 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3600 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3601 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3660 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3661 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3720 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3721 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3780 Query: 579 SPSST 583 +P++T Sbjct: 3781 TPTTT 3785 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3281 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3340 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3341 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3394 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3395 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3451 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3452 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3506 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3507 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3564 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3565 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3623 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3624 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3683 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3743 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3744 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3803 Query: 579 SPSST 583 +P++T Sbjct: 3804 TPTTT 3808 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3363 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3364 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3417 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3418 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3474 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3475 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3529 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3530 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3587 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3588 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3646 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3647 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3706 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3707 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3766 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3767 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3826 Query: 579 SPSST 583 +P++T Sbjct: 3827 TPTTT 3831 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3327 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3386 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3387 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3440 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3441 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3497 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3498 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3552 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3553 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3610 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3611 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3669 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3670 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3729 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3730 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3789 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3790 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3849 Query: 579 SPSST 583 +P++T Sbjct: 3850 TPTTT 3854 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3409 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3410 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3463 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3464 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3520 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3521 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3575 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3576 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3633 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3634 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3692 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3693 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3752 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3812 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3813 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3872 Query: 579 SPSST 583 +P++T Sbjct: 3873 TPTTT 3877 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3373 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3432 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3433 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3486 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3487 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3543 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3544 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3598 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3599 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3656 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3657 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3715 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3716 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3775 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3776 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3835 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3836 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3895 Query: 579 SPSST 583 +P++T Sbjct: 3896 TPTTT 3900 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3396 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3455 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3456 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3509 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3510 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3566 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3567 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3621 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3622 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3679 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3680 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3738 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3739 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3798 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3799 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3858 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3859 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3918 Query: 579 SPSST 583 +P++T Sbjct: 3919 TPTTT 3923 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3419 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3478 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3479 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3532 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3533 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3589 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3590 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3644 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3645 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3702 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3703 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3761 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3762 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3881 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3882 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3941 Query: 579 SPSST 583 +P++T Sbjct: 3942 TPTTT 3946 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3501 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3502 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3555 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3556 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3612 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3613 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3667 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3668 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3725 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3726 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3784 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3785 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3844 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3845 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3904 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3905 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3964 Query: 579 SPSST 583 +P++T Sbjct: 3965 TPTTT 3969 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3465 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3524 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3525 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3578 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3579 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3635 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3636 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3690 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3691 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3748 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3749 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3807 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3808 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3867 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3868 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3927 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3928 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 3987 Query: 579 SPSST 583 +P++T Sbjct: 3988 TPTTT 3992 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3488 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3547 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3548 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3601 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3602 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3658 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3659 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3713 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3771 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3772 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3830 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3831 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3890 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3950 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3951 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4010 Query: 579 SPSST 583 +P++T Sbjct: 4011 TPTTT 4015 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3511 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3570 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3571 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3624 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3625 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3681 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3682 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3736 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3737 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3794 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3795 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3853 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3854 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3914 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3973 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3974 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4033 Query: 579 SPSST 583 +P++T Sbjct: 4034 TPTTT 4038 Score = 92.4 bits (228), Expect = 1e-18 Identities = 116/605 (19%), Positives = 197/605 (32%), Gaps = 64/605 (10%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3534 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3593 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3594 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 3647 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 3648 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 3704 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPP 310 P P G Q P TP P P P++++ TP+P+ P+ + P Sbjct: 3705 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTP 3759 Query: 311 SLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367 + + + P+ T +PT + T + P+P +P T P P + Sbjct: 3760 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVT 3817 Query: 368 APPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFS 414 P+P P + P++ T +P Q P + +P P+P Q P + Sbjct: 3818 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTT 3876 Query: 415 PP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PL 471 P + V+P+ TP P+ +P +P + + T P P P Sbjct: 3877 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3936 Query: 472 QLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLA 528 P P T + P+P + P P + + ++ +P T P P+ Sbjct: 3937 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 3996 Query: 529 APLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSR 578 + P+P P + T P G T + P T + P P P ++ Sbjct: 3997 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 4056 Query: 579 SPSST 583 +P++T Sbjct: 4057 TPTTT 4061 Score = 90.9 bits (224), Expect = 4e-18 Identities = 109/560 (19%), Positives = 188/560 (33%), Gaps = 64/560 (11%) Query: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130 P P T T+ P + P + P ++P + T P P + Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 1968 Query: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 T P + + T TP+P GT+ P + Sbjct: 1969 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTV 2022 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG--- 247 PT P + + + TT + P+ G Q P + ++++ T +P +G Sbjct: 2023 TPTPTPTGTQTPTTTPITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQT 2079 Query: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPL 295 P+ P P G Q P TP P P P++++ Sbjct: 2080 PTTTPITTTTTVTPTPTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2136 Query: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLAT 352 TP+P+ P+ + P+ + + P+ T +PT + T + P+P +P T Sbjct: 2137 VTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGT 2192 Query: 353 PPPQAPPALALPPLQAPPSP-----PASPPLSPLATPSP-------QAPNALAVHLLQAP 400 P P + P+P P + P++ T +P Q P + Sbjct: 2193 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTT 2251 Query: 401 FSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457 +P P+P Q P + P + V+P+ TP P+ +P +P + + T Sbjct: 2252 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2311 Query: 458 PPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSP 515 P P P P P T + P+P + P P + + ++ +P Sbjct: 2312 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2371 Query: 516 L--ATPPPQAPPVLAAPLLQVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-R 563 T P P+ + P+P P + T P G T + P Sbjct: 2372 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT 2431 Query: 564 LTLALAPGPPPPPSRSPSST 583 T + P P P +++P++T Sbjct: 2432 TTTTVTPTPTPTGTQTPTTT 2451 Score = 87.4 bits (215), Expect = 5e-17 Identities = 98/481 (20%), Positives = 169/481 (35%), Gaps = 63/481 (13%) Query: 155 TSGPTPGTPSPAMARRS-----RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 209 T PTP T +P + GT+ P + PT P + + + TT Sbjct: 1890 TENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT 1949 Query: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQPKPK 266 + P+ G Q P + ++++ T +P +G P+ P P Sbjct: 1950 TTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006 Query: 267 GLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQT 314 G Q P TP P P P++++ TP+P+ P+ + P+ Sbjct: 2007 GTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTP 2061 Query: 315 LPSPPATPPSQATTSLGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371 + + P+ T +PT + T + P+P +P T P P + P+ Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPT 2119 Query: 372 P-----PASPPLSPLATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP-- 416 P P + P++ T +P Q P + +P P+P Q P + P Sbjct: 2120 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPIT 2178 Query: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAK 475 + V+P+ TP P+ +P +P + + T P P P Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2238 Query: 476 PPPQAPPALATPPLQALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLL 532 P P T + P+P + P P + + ++ +P T P P+ + Sbjct: 2239 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2298 Query: 533 QVPPSP---------PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSS 582 P+P P + T P G T + P T + P P P +++P++ Sbjct: 2299 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2358 Query: 583 T 583 T Sbjct: 2359 T 2359 Score = 86.7 bits (213), Expect = 8e-17 Identities = 106/526 (20%), Positives = 181/526 (34%), Gaps = 69/526 (13%) Query: 105 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 164 V+ P + TT P I+ TV T P + + T TP+ Sbjct: 1879 VTQPTTMTTTTTENPTPPTTTPITTTTTV-----TPTPTPTGTQTPTTTPITTTTTVTPT 1933 Query: 165 PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224 P GT+ P + PT P + + + TT + P+ G Sbjct: 1934 PT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT---G 1984 Query: 225 LQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQPKPKGLQALRPPQVTP--- 278 Q P + ++++ T +P +G P+ P P G Q P TP Sbjct: 1985 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT---PTTTPITT 2041 Query: 279 ---------PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 P P P++++ TP+P+ P+ + P+ + + P+ T Sbjct: 2042 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTG 2099 Query: 330 LGSPT---LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP-----PASPPLSPL 381 +PT + T + P+P +P T P P + P+P P + P++ Sbjct: 2100 TQTPTTTPITTTTTVTPTP--TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTT 2157 Query: 382 ATPSP-------QAPNALAVHLLQAPFSPPPSPP-VQAPFSPP--ASPPVSPSATPPSQA 431 T +P Q P + +P P+P Q P + P + V+P+ TP Sbjct: 2158 TTVTPTPTPTGTQTPTTTPI-TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2216 Query: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQ 490 P+ +P +P + + T P P P P P T + Sbjct: 2217 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2276 Query: 491 ALPSPPAS-FPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSP--------- 538 P+P + P P + + ++ +P T P P+ + P+P Sbjct: 2277 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2336 Query: 539 PASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPGPPPPPSRSPSST 583 P + T P G T + P T + P P P +++P++T Sbjct: 2337 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2382 Score = 80.5 bits (197), Expect = 6e-15 Identities = 118/582 (20%), Positives = 181/582 (31%), Gaps = 83/582 (14%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 3984 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 3985 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4038 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 4039 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4095 Query: 263 PKPKGLQALRPPQVTP------------PRKDAAPALGPLSSSPLATPSPS--APPSPSA 308 P P G Q P TP P P P++++ TP+P+ +P+ Sbjct: 4096 PTPTGTQT---PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 4152 Query: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-Q 367 P T P P+ T +P + T + P+P + T PP + L Sbjct: 4153 TPITTTTTVTPTPTPTGTQTPTTTP-ITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTT 4211 Query: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATP 427 + P P +S P + +T SP + + L P ++ + P S P +P+ T Sbjct: 4212 SNPPPESSTPQTSRSTSSPLTESTTLLSTL--------PPAIEMTSTAPPSTPTAPTTTS 4263 Query: 428 PSQAPPSLAAPPLQVPPSPPASPPMSP--------SATPPPQAPPPLAAPPLQLAKPPPQ 479 L PPS SPP +P S+ P P P Sbjct: 4264 GGHT--------LSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLS 4315 Query: 480 APPALATPPLQALPS---------PPASFPGQAPF-------------SPSASLPM---S 514 P + T L+ PS PG+ + S S +L S Sbjct: 4316 TPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSCTLEFYNWS 4375 Query: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556 +TP P P + P P S P+ PT P P PD Sbjct: 4376 CPSTPSPTPTPSKSTPTPSKPSSTPSKPT---PGTKPPECPD 4414 Score = 77.4 bits (189), Expect = 5e-14 Identities = 101/477 (21%), Positives = 157/477 (32%), Gaps = 54/477 (11%) Query: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85 TP P G+ P V G + P P T T+ P Sbjct: 3957 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016 Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 + P + P ++P + T P P + T P + Sbjct: 4017 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4076 Query: 146 ALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE 205 + T TP+P GT+ P + PT P + + + Sbjct: 4077 GTQTPTTTPITTTTTVTPTPT------PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 4130 Query: 206 HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG---PSARGTPRAPAHPSQ 262 TT + P+ G Q P + ++++ T +P +G P+ Sbjct: 4131 PITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4187 Query: 263 PKPKGLQALRPPQVT-----------PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311 P P G Q P + PP + + P +SSPL + S + PP+ Sbjct: 4188 PTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPL---TESTTLLSTLPPA 4244 Query: 312 LQ-TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPP 370 ++ T +PP+TP + TTS G TL S SPP +P + A +Q Sbjct: 4245 IEMTSTAPPSTPTAPTTTS-GGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTT 4303 Query: 371 SPPASPPLSPLATPS--------PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA----- 417 + +P +PL+TPS P + L +L + P + Sbjct: 4304 TSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNC 4363 Query: 418 -----------SPPVSPSATP-PSQAPPSLAAPP-LQVPPSPPASPPMSPSATPPPQ 461 S P +PS TP PS++ P+ + P P+P PP P PP Q Sbjct: 4364 SLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPPRQ 4420 >gi|189181724 proteoglycan 4 isoform D [Homo sapiens] Length = 1270 Score = 148 bits (373), Expect = 2e-35 Identities = 177/688 (25%), Positives = 248/688 (36%), Gaps = 97/688 (14%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 K + G A TP P TP+ P S P P TP ++ +A ++P Sbjct: 200 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 247 Query: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 T +SAP T + PA + P P P ++ A TT+ P K Sbjct: 248 ---APTTTKSAPT-----TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 299 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 182 T + A PK A + PTP TP PA + A T Sbjct: 300 ----EPAPTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPAPTTP---KE 347 Query: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 PAP+A +P P++ + + EP+P + PS + PA + S+ T Sbjct: 348 PAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTP-KEPAPTTTKSAPTTTKE 402 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 PA + T AP P +P P + P TP K+ AP P +P TP A Sbjct: 403 PAPTT-----TKSAPTTPKEPSPTTTK--EPAPTTP--KEPAPTT-PKKPAP-TTPKEPA 451 Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 P +P P T P TP A T+ P+ P T P + PA Sbjct: 452 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK--PAPT 509 Query: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 P AP +P P +P P+P P A A + + P P +P AP +P P + Sbjct: 510 TPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPTT 566 Query: 423 PSATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479 P T P+ P+ P P PA ++P+ T P + KP P Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT--------CDKPAPT 618 Query: 480 APPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 P A T P + P+ P AP +P + P + L P P P A ++ P+ Sbjct: 619 TPKGTAPTTPKEPAPTTPKE---PAPTTPKGTAPTT-LKEPAPTTPKKPAPK--ELAPTT 672 Query: 539 PASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 PT +P PT +T+ + P+ P P P +P++ + P S+ T Sbjct: 673 TKGPTSTTSDKPAPTTPKETAPTTPK-----EPAPTTPKKPAPTTPETPPPTTSEVSTPT 727 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 +T E + S E S P P A P PG P PA Sbjct: 728 TTKEPTTIHKSPDESTPELSAEPT-------PKALENSPK-------EPGVPTTKTPAAT 773 Query: 658 PGSADGLCTIYETE-----GPESATPAP 680 TE PE+ T AP Sbjct: 774 KPEMTTTAKDKTTERDLRTTPETTTAAP 801 Score = 147 bits (372), Expect = 3e-35 Identities = 171/671 (25%), Positives = 243/671 (36%), Gaps = 66/671 (9%) Query: 55 RKPLAERAG-GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG 113 + P+ + AG G+ + P T+ ++ S + AK +P P P S Sbjct: 81 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS---PKITTAKPINPRPSLPPN--SD 135 Query: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173 T++ + L ++ E TV + T K+++ G + TS T S Sbjct: 136 TSK-----ETSLTVNKETTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDL 187 Query: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 A T L +P P A T+GP ++++ E + T P A P + P ++ Sbjct: 188 APTSKVLAKPTPKAETT--TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTI 237 Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S+ T PA + T AP P +P P + P TP K+ AP + Sbjct: 238 KSAPTTPKEPAPTT-----TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAPT---TTKE 285 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 P T + SAP +P P P TP A T+ PT P+ P P T Sbjct: 286 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--------PTTPKEPAPTT 337 Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 AP P AP P + P P TP AP P P P+ AP Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 397 Query: 413 FS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLA 467 + P + S TP +P + P P P + P P+ T P + P P Sbjct: 398 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 457 Query: 468 APPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APP 525 P KP P P A T P + P+ P P + + P P T P + AP Sbjct: 458 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 517 Query: 526 VLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 P P P P +P AP P P P T+ P T P P P +P +T Sbjct: 518 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTP 575 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFR 643 G A +TP++ P+ A + PA + +G AP Sbjct: 576 KGTAPTTLKEPAPTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630 Query: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGA 700 AP P P T G+A T+ E PAP L P + G T+ K A Sbjct: 631 PAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 688 Query: 701 GAGASSRSPKQ 711 + +PK+ Sbjct: 689 PKETAPTTPKE 699 Score = 146 bits (369), Expect = 7e-35 Identities = 165/612 (26%), Positives = 225/612 (36%), Gaps = 86/612 (14%) Query: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 ET +G A PK + ++ + TP P+P + + E PAP+ Sbjct: 202 ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTPKE-----PAPTTTKS 254 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 PT P++ + +T EP+P + P A + PA + S+ T PA + P Sbjct: 255 APTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPK- 307 Query: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-------TPSPSAP 303 + P P P+ PK P + P K+ AP P +P A TP AP Sbjct: 308 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPKKPAPTTPKEPAP 366 Query: 304 PSPSAPPSLQTLPSPPATPPSQA-TTSLGSPTLQ-----ATHSFLPSPPLSPLATPPPQA 357 +P P T P TP A TT+ +PT T P+ P P +P Sbjct: 367 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTK 424 Query: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 PA P AP +P P +P P+P P A + P P +P AP +P Sbjct: 425 EPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKE 481 Query: 418 SPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPL 471 + P +P TP AP + P P + P P+ T P + P P AA P Sbjct: 482 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 541 Query: 472 QLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 +P P P PA TP A +P + P + +L TP AP LA Sbjct: 542 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601 Query: 530 PLLQVPPSP------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 + P S P +P AP P P P T P P P +P+ T Sbjct: 602 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-T 651 Query: 584 LSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPL 640 L P ++ P+EL + GP + P P E A P + PAP Sbjct: 652 LKEP---APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT- 703 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE-------------SATPAPGALDPGP 687 P P P P T P + + T T+ P SA P P AL+ P Sbjct: 704 ----TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 759 Query: 688 -SPGTSGGKAAA 698 PG K A Sbjct: 760 KEPGVPTTKTPA 771 Score = 96.7 bits (239), Expect = 8e-20 Identities = 142/603 (23%), Positives = 204/603 (33%), Gaps = 68/603 (11%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 K A + PA AP P P P P P PA + ++P A Sbjct: 338 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-APTTTKSA 396 Query: 67 GATIPESAP---RAGPTRTSRPPASGRGERAP-----PAKNTSPGPV-SSPGRASGTT-- 115 T E AP ++ PT P + E AP PA T P ++P + TT Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP---TPGTPS-PAMARRS 171 P P K T + A PK +A + + + P P TP PA Sbjct: 457 EPAPTTTK----KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 A T P P P P T +A+ ++ EP+P + P A + PA Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTP------KAAAPNTPKEPAPTTPKEP-APTTPKEPAPT 565 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 + +A ++P + P+ P AP P +P PK L + T D P Sbjct: 566 TPKETAP--TTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 622 Query: 292 SSPLAT--PSPSAP--PSPSAPPSLQ--TLPSP-PATPPSQATTSLGSPTLQ---ATHSF 341 ++P P+P+ P P+P+ P TL P P TP A L T + +T S Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682 Query: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 P+P P PA P AP +P PP + + +H Sbjct: 683 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 742 Query: 402 SPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPP 451 +P S P +A + P P V + TP + P + P + A+P Sbjct: 743 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 802 Query: 452 MSP--SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--- 506 M+ + T + A Q+ Q L+ P + + Sbjct: 803 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 862 Query: 507 ----------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGP 555 P S TP PQ P AP P + P ++ P+ PTP Sbjct: 863 IMNKPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920 Query: 556 DTS 558 TS Sbjct: 921 MTS 923 >gi|189181722 proteoglycan 4 isoform C [Homo sapiens] Length = 1311 Score = 148 bits (373), Expect = 2e-35 Identities = 177/688 (25%), Positives = 248/688 (36%), Gaps = 97/688 (14%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 K + G A TP P TP+ P S P P TP ++ +A ++P Sbjct: 241 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 288 Query: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 T +SAP T + PA + P P P ++ A TT+ P K Sbjct: 289 ---APTTTKSAPT-----TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 340 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 182 T + A PK A + PTP TP PA + A T Sbjct: 341 ----EPAPTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPAPTTP---KE 388 Query: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 PAP+A +P P++ + + EP+P + PS + PA + S+ T Sbjct: 389 PAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTP-KEPAPTTTKSAPTTTKE 443 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 PA + T AP P +P P + P TP K+ AP P +P TP A Sbjct: 444 PAPTT-----TKSAPTTPKEPSPTTTK--EPAPTTP--KEPAPTT-PKKPAP-TTPKEPA 492 Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 P +P P T P TP A T+ P+ P T P + PA Sbjct: 493 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK--PAPT 550 Query: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 P AP +P P +P P+P P A A + + P P +P AP +P P + Sbjct: 551 TPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPTT 607 Query: 423 PSATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479 P T P+ P+ P P PA ++P+ T P + KP P Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT--------CDKPAPT 659 Query: 480 APPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 P A T P + P+ P AP +P + P + L P P P A ++ P+ Sbjct: 660 TPKGTAPTTPKEPAPTTPKE---PAPTTPKGTAPTT-LKEPAPTTPKKPAPK--ELAPTT 713 Query: 539 PASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 PT +P PT +T+ + P+ P P P +P++ + P S+ T Sbjct: 714 TKGPTSTTSDKPAPTTPKETAPTTPK-----EPAPTTPKKPAPTTPETPPPTTSEVSTPT 768 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 +T E + S E S P P A P PG P PA Sbjct: 769 TTKEPTTIHKSPDESTPELSAEPT-------PKALENSPK-------EPGVPTTKTPAAT 814 Query: 658 PGSADGLCTIYETE-----GPESATPAP 680 TE PE+ T AP Sbjct: 815 KPEMTTTAKDKTTERDLRTTPETTTAAP 842 Score = 147 bits (372), Expect = 3e-35 Identities = 171/671 (25%), Positives = 243/671 (36%), Gaps = 66/671 (9%) Query: 55 RKPLAERAG-GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG 113 + P+ + AG G+ + P T+ ++ S + AK +P P P S Sbjct: 122 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS---PKITTAKPINPRPSLPPN--SD 176 Query: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173 T++ + L ++ E TV + T K+++ G + TS T S Sbjct: 177 TSK-----ETSLTVNKETTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDL 228 Query: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 A T L +P P A T+GP ++++ E + T P A P + P ++ Sbjct: 229 APTSKVLAKPTPKAETT--TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTI 278 Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S+ T PA + T AP P +P P + P TP K+ AP + Sbjct: 279 KSAPTTPKEPAPTT-----TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAPT---TTKE 326 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 P T + SAP +P P P TP A T+ PT P+ P P T Sbjct: 327 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--------PTTPKEPAPTT 378 Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 AP P AP P + P P TP AP P P P+ AP Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 438 Query: 413 FS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLA 467 + P + S TP +P + P P P + P P+ T P + P P Sbjct: 439 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 498 Query: 468 APPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APP 525 P KP P P A T P + P+ P P + + P P T P + AP Sbjct: 499 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 558 Query: 526 VLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 P P P P +P AP P P P T+ P T P P P +P +T Sbjct: 559 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTP 616 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFR 643 G A +TP++ P+ A + PA + +G AP Sbjct: 617 KGTAPTTLKEPAPTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671 Query: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGA 700 AP P P T G+A T+ E PAP L P + G T+ K A Sbjct: 672 PAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 729 Query: 701 GAGASSRSPKQ 711 + +PK+ Sbjct: 730 PKETAPTTPKE 740 Score = 146 bits (369), Expect = 7e-35 Identities = 165/612 (26%), Positives = 225/612 (36%), Gaps = 86/612 (14%) Query: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 ET +G A PK + ++ + TP P+P + + E PAP+ Sbjct: 243 ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTPKE-----PAPTTTKS 295 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 PT P++ + +T EP+P + P A + PA + S+ T PA + P Sbjct: 296 APTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPK- 348 Query: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-------TPSPSAP 303 + P P P+ PK P + P K+ AP P +P A TP AP Sbjct: 349 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPKKPAPTTPKEPAP 407 Query: 304 PSPSAPPSLQTLPSPPATPPSQA-TTSLGSPTLQ-----ATHSFLPSPPLSPLATPPPQA 357 +P P T P TP A TT+ +PT T P+ P P +P Sbjct: 408 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTK 465 Query: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 PA P AP +P P +P P+P P A + P P +P AP +P Sbjct: 466 EPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKE 522 Query: 418 SPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPL 471 + P +P TP AP + P P + P P+ T P + P P AA P Sbjct: 523 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 582 Query: 472 QLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 +P P P PA TP A +P + P + +L TP AP LA Sbjct: 583 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642 Query: 530 PLLQVPPSP------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 + P S P +P AP P P P T P P P +P+ T Sbjct: 643 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-T 692 Query: 584 LSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPL 640 L P ++ P+EL + GP + P P E A P + PAP Sbjct: 693 LKEP---APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT- 744 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE-------------SATPAPGALDPGP 687 P P P P T P + + T T+ P SA P P AL+ P Sbjct: 745 ----TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 800 Query: 688 -SPGTSGGKAAA 698 PG K A Sbjct: 801 KEPGVPTTKTPA 812 Score = 96.7 bits (239), Expect = 8e-20 Identities = 142/603 (23%), Positives = 204/603 (33%), Gaps = 68/603 (11%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 K A + PA AP P P P P P PA + ++P A Sbjct: 379 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-APTTTKSA 437 Query: 67 GATIPESAP---RAGPTRTSRPPASGRGERAP-----PAKNTSPGPV-SSPGRASGTT-- 115 T E AP ++ PT P + E AP PA T P ++P + TT Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP---TPGTPS-PAMARRS 171 P P K T + A PK +A + + + P P TP PA Sbjct: 498 EPAPTTTK----KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 A T P P P P T +A+ ++ EP+P + P A + PA Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTP------KAAAPNTPKEPAPTTPKEP-APTTPKEPAPT 606 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 + +A ++P + P+ P AP P +P PK L + T D P Sbjct: 607 TPKETAP--TTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 663 Query: 292 SSPLAT--PSPSAP--PSPSAPPSLQ--TLPSP-PATPPSQATTSLGSPTLQ---ATHSF 341 ++P P+P+ P P+P+ P TL P P TP A L T + +T S Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723 Query: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 P+P P PA P AP +P PP + + +H Sbjct: 724 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 783 Query: 402 SPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPP 451 +P S P +A + P P V + TP + P + P + A+P Sbjct: 784 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 843 Query: 452 MSP--SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--- 506 M+ + T + A Q+ Q L+ P + + Sbjct: 844 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 903 Query: 507 ----------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGP 555 P S TP PQ P AP P + P ++ P+ PTP Sbjct: 904 IMNKPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961 Query: 556 DTS 558 TS Sbjct: 962 MTS 964 >gi|189181720 proteoglycan 4 isoform B [Homo sapiens] Length = 1363 Score = 148 bits (373), Expect = 2e-35 Identities = 177/688 (25%), Positives = 248/688 (36%), Gaps = 97/688 (14%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 K + G A TP P TP+ P S P P TP ++ +A ++P Sbjct: 293 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 340 Query: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 T +SAP T + PA + P P P ++ A TT+ P K Sbjct: 341 ---APTTTKSAPT-----TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 392 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 182 T + A PK A + PTP TP PA + A T Sbjct: 393 ----EPAPTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPAPTTP---KE 440 Query: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 PAP+A +P P++ + + EP+P + PS + PA + S+ T Sbjct: 441 PAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTP-KEPAPTTTKSAPTTTKE 495 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 PA + T AP P +P P + P TP K+ AP P +P TP A Sbjct: 496 PAPTT-----TKSAPTTPKEPSPTTTK--EPAPTTP--KEPAPTT-PKKPAP-TTPKEPA 544 Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 P +P P T P TP A T+ P+ P T P + PA Sbjct: 545 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK--PAPT 602 Query: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 P AP +P P +P P+P P A A + + P P +P AP +P P + Sbjct: 603 TPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPTT 659 Query: 423 PSATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479 P T P+ P+ P P PA ++P+ T P + KP P Sbjct: 660 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT--------CDKPAPT 711 Query: 480 APPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 P A T P + P+ P AP +P + P + L P P P A ++ P+ Sbjct: 712 TPKGTAPTTPKEPAPTTPKE---PAPTTPKGTAPTT-LKEPAPTTPKKPAPK--ELAPTT 765 Query: 539 PASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 PT +P PT +T+ + P+ P P P +P++ + P S+ T Sbjct: 766 TKGPTSTTSDKPAPTTPKETAPTTPK-----EPAPTTPKKPAPTTPETPPPTTSEVSTPT 820 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 +T E + S E S P P A P PG P PA Sbjct: 821 TTKEPTTIHKSPDESTPELSAEPT-------PKALENSPK-------EPGVPTTKTPAAT 866 Query: 658 PGSADGLCTIYETE-----GPESATPAP 680 TE PE+ T AP Sbjct: 867 KPEMTTTAKDKTTERDLRTTPETTTAAP 894 Score = 147 bits (372), Expect = 3e-35 Identities = 171/671 (25%), Positives = 243/671 (36%), Gaps = 66/671 (9%) Query: 55 RKPLAERAG-GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG 113 + P+ + AG G+ + P T+ ++ S + AK +P P P S Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS---PKITTAKPINPRPSLPPN--SD 228 Query: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173 T++ + L ++ E TV + T K+++ G + TS T S Sbjct: 229 TSK-----ETSLTVNKETTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDL 280 Query: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 A T L +P P A T+GP ++++ E + T P A P + P ++ Sbjct: 281 APTSKVLAKPTPKAETT--TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTI 330 Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S+ T PA + T AP P +P P + P TP K+ AP + Sbjct: 331 KSAPTTPKEPAPTT-----TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAPT---TTKE 378 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 P T + SAP +P P P TP A T+ PT P+ P P T Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--------PTTPKEPAPTT 430 Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 AP P AP P + P P TP AP P P P+ AP Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 490 Query: 413 FS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLA 467 + P + S TP +P + P P P + P P+ T P + P P Sbjct: 491 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 550 Query: 468 APPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APP 525 P KP P P A T P + P+ P P + + P P T P + AP Sbjct: 551 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 610 Query: 526 VLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 P P P P +P AP P P P T+ P T P P P +P +T Sbjct: 611 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTP 668 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFR 643 G A +TP++ P+ A + PA + +G AP Sbjct: 669 KGTAPTTLKEPAPTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723 Query: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGA 700 AP P P T G+A T+ E PAP L P + G T+ K A Sbjct: 724 PAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 781 Query: 701 GAGASSRSPKQ 711 + +PK+ Sbjct: 782 PKETAPTTPKE 792 Score = 146 bits (369), Expect = 7e-35 Identities = 165/612 (26%), Positives = 225/612 (36%), Gaps = 86/612 (14%) Query: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 ET +G A PK + ++ + TP P+P + + E PAP+ Sbjct: 295 ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTPKE-----PAPTTTKS 347 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 PT P++ + +T EP+P + P A + PA + S+ T PA + P Sbjct: 348 APTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPK- 400 Query: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-------TPSPSAP 303 + P P P+ PK P + P K+ AP P +P A TP AP Sbjct: 401 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPKKPAPTTPKEPAP 459 Query: 304 PSPSAPPSLQTLPSPPATPPSQA-TTSLGSPTLQ-----ATHSFLPSPPLSPLATPPPQA 357 +P P T P TP A TT+ +PT T P+ P P +P Sbjct: 460 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTK 517 Query: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 PA P AP +P P +P P+P P A + P P +P AP +P Sbjct: 518 EPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKE 574 Query: 418 SPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPL 471 + P +P TP AP + P P + P P+ T P + P P AA P Sbjct: 575 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 634 Query: 472 QLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 +P P P PA TP A +P + P + +L TP AP LA Sbjct: 635 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694 Query: 530 PLLQVPPSP------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 + P S P +P AP P P P T P P P +P+ T Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-T 744 Query: 584 LSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPL 640 L P ++ P+EL + GP + P P E A P + PAP Sbjct: 745 LKEP---APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT- 796 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE-------------SATPAPGALDPGP 687 P P P P T P + + T T+ P SA P P AL+ P Sbjct: 797 ----TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 852 Query: 688 -SPGTSGGKAAA 698 PG K A Sbjct: 853 KEPGVPTTKTPA 864 Score = 114 bits (284), Expect = 5e-25 Identities = 121/543 (22%), Positives = 183/543 (33%), Gaps = 55/543 (10%) Query: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR----------PSAGGGLQ 226 EV P PS++ PP G +++ S ++ S P+ ++ S + Sbjct: 65 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 124 Query: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286 +S S SSS++ + S SA + K +P P +A Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 184 Query: 287 L-----------------GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 L +S+SP T + P PS PP+ T T + T Sbjct: 185 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 244 Query: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389 T + + A ++ + +P LA P+P+A Sbjct: 245 TKETTTTNKQTSTDG---------KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 295 Query: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 L P P P+ P + P ++ P P+ T AP + P S P + Sbjct: 296 TTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351 Query: 450 P-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 P +P+ T P P P +P P + T P + P+ P P P+ Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411 Query: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLA 567 + P P T P + P P P P P +P AP P P P T+ P T Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP-TTPKEPAPTTT 470 Query: 568 LAPGPPPPPSRSPSSTLSGPDLAGH-----SSSATSTPEE------LRGYDSGPEGGAAA 616 P P P +P++T S P + SA +TP+E + P+ A Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530 Query: 617 SPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 675 +P A PA + + PAP + AP P P T +A PE Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 590 Query: 676 ATP 678 P Sbjct: 591 LAP 593 Score = 96.7 bits (239), Expect = 8e-20 Identities = 142/603 (23%), Positives = 204/603 (33%), Gaps = 68/603 (11%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 K A + PA AP P P P P P PA + ++P A Sbjct: 431 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-APTTTKSA 489 Query: 67 GATIPESAP---RAGPTRTSRPPASGRGERAP-----PAKNTSPGPV-SSPGRASGTT-- 115 T E AP ++ PT P + E AP PA T P ++P + TT Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP---TPGTPS-PAMARRS 171 P P K T + A PK +A + + + P P TP PA Sbjct: 550 EPAPTTTK----KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 A T P P P P T +A+ ++ EP+P + P A + PA Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTP------KAAAPNTPKEPAPTTPKEP-APTTPKEPAPT 658 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 + +A ++P + P+ P AP P +P PK L + T D P Sbjct: 659 TPKETAP--TTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715 Query: 292 SSPLAT--PSPSAP--PSPSAPPSLQ--TLPSP-PATPPSQATTSLGSPTLQ---ATHSF 341 ++P P+P+ P P+P+ P TL P P TP A L T + +T S Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775 Query: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 P+P P PA P AP +P PP + + +H Sbjct: 776 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 835 Query: 402 SPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPP 451 +P S P +A + P P V + TP + P + P + A+P Sbjct: 836 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 895 Query: 452 MSP--SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--- 506 M+ + T + A Q+ Q L+ P + + Sbjct: 896 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 955 Query: 507 ----------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGP 555 P S TP PQ P AP P + P ++ P+ PTP Sbjct: 956 IMNKPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013 Query: 556 DTS 558 TS Sbjct: 1014 MTS 1016 >gi|67190163 proteoglycan 4 isoform A [Homo sapiens] Length = 1404 Score = 148 bits (373), Expect = 2e-35 Identities = 177/688 (25%), Positives = 248/688 (36%), Gaps = 97/688 (14%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 K + G A TP P TP+ P S P P TP ++ +A ++P Sbjct: 334 KAETTTKGPALTTPKEPTP--TTPKEPASTTPKEP-TPTTIK---SAPTTPKEP------ 381 Query: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 T +SAP T + PA + P P P ++ A TT+ P K Sbjct: 382 ---APTTTKSAPT-----TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPK 433 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPR 182 T + A PK A + PTP TP PA + A T Sbjct: 434 ----EPAPTTPKKPAPTTPKEPAPTTPKE-----PTPTTPKEPAPTTKEPAPTTP---KE 481 Query: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 PAP+A +P P++ + + EP+P + PS + PA + S+ T Sbjct: 482 PAPTAPKKPAPTTPKEPAPTTPK----EPAPTTTKEPSPTTP-KEPAPTTTKSAPTTTKE 536 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 PA + T AP P +P P + P TP K+ AP P +P TP A Sbjct: 537 PAPTT-----TKSAPTTPKEPSPTTTK--EPAPTTP--KEPAPTT-PKKPAP-TTPKEPA 585 Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362 P +P P T P TP A T+ P+ P T P + PA Sbjct: 586 PTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK--PAPT 643 Query: 363 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 P AP +P P +P P+P P A A + + P P +P AP +P P + Sbjct: 644 TPEELAPTTPEEPTPTTP-EEPAPTTPKAAAPNTPKEP--APTTPKEPAPTTPKEPAPTT 700 Query: 423 PSATPPSQ---APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479 P T P+ P+ P P PA ++P+ T P + KP P Sbjct: 701 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT--------CDKPAPT 752 Query: 480 APPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 P A T P + P+ P AP +P + P + L P P P A ++ P+ Sbjct: 753 TPKGTAPTTPKEPAPTTPKE---PAPTTPKGTAPTT-LKEPAPTTPKKPAPK--ELAPTT 806 Query: 539 PASPTLQAPRRP-PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 PT +P PT +T+ + P+ P P P +P++ + P S+ T Sbjct: 807 TKGPTSTTSDKPAPTTPKETAPTTPK-----EPAPTTPKKPAPTTPETPPPTTSEVSTPT 861 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 657 +T E + S E S P P A P PG P PA Sbjct: 862 TTKEPTTIHKSPDESTPELSAEPT-------PKALENSPK-------EPGVPTTKTPAAT 907 Query: 658 PGSADGLCTIYETE-----GPESATPAP 680 TE PE+ T AP Sbjct: 908 KPEMTTTAKDKTTERDLRTTPETTTAAP 935 Score = 147 bits (372), Expect = 3e-35 Identities = 171/671 (25%), Positives = 243/671 (36%), Gaps = 66/671 (9%) Query: 55 RKPLAERAG-GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASG 113 + P+ + AG G+ + P T+ ++ S + AK +P P P S Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTS---PKITTAKPINPRPSLPPN--SD 269 Query: 114 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 173 T++ + L ++ E TV + T K+++ G + TS T S Sbjct: 270 TSK-----ETSLTVNKETTVETKETTTTNKQTSTD-GKEKTTSAKE--TQSIEKTSAKDL 321 Query: 174 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 A T L +P P A T+GP ++++ E + T P A P + P ++ Sbjct: 322 APTSKVLAKPTPKAETT--TKGP--ALTTPKEPTPTTPKEPASTTP------KEPTPTTI 371 Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S+ T PA + T AP P +P P + P TP K+ AP + Sbjct: 372 KSAPTTPKEPAPTT-----TKSAPTTPKEPAPTTTK--EPAPTTP--KEPAPT---TTKE 419 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 P T + SAP +P P P TP A T+ PT P+ P P T Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPT--------PTTPKEPAPTT 471 Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPL-ATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 412 AP P AP P + P P TP AP P P P+ AP Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAP 531 Query: 413 FS---PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLA 467 + P + S TP +P + P P P + P P+ T P + P P Sbjct: 532 TTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKE 591 Query: 468 APPLQLAKPPPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ-APP 525 P KP P P A T P + P+ P P + + P P T P + AP Sbjct: 592 PAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPT 651 Query: 526 VLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 P P P P +P AP P P P T+ P T P P P +P +T Sbjct: 652 TPEEPTPTTPEEPAPTTPKAAAPNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAP-TTP 709 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFR 643 G A +TP++ P+ A + PA + +G AP Sbjct: 710 KGTAPTTLKEPAPTTPKK-----PAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764 Query: 644 GAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG---TSGGKAAAGA 700 AP P P T G+A T+ E PAP L P + G T+ K A Sbjct: 765 PAPTTPKEPAPTTPKGTAP--TTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT 822 Query: 701 GAGASSRSPKQ 711 + +PK+ Sbjct: 823 PKETAPTTPKE 833 Score = 146 bits (369), Expect = 7e-35 Identities = 165/612 (26%), Positives = 225/612 (36%), Gaps = 86/612 (14%) Query: 131 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 190 ET +G A PK + ++ + TP P+P + + E PAP+ Sbjct: 336 ETTTKGPALTTPKEPTPTTP--KEPASTTPKEPTPTTIKSAPTTPKE-----PAPTTTKS 388 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 250 PT P++ + +T EP+P + P A + PA + S+ T PA + P Sbjct: 389 APTT-PKEPAPT----TTKEPAPTTPKEP-APTTTKEPAPTTTKSAPTTPKEPAPTTPK- 441 Query: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-------TPSPSAP 303 + P P P+ PK P + P K+ AP P +P A TP AP Sbjct: 442 KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT-PKEPAPTAPKKPAPTTPKEPAP 500 Query: 304 PSPSAPPSLQTLPSPPATPPSQA-TTSLGSPTLQ-----ATHSFLPSPPLSPLATPPPQA 357 +P P T P TP A TT+ +PT T P+ P P +P Sbjct: 501 TTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP--SPTTTK 558 Query: 358 PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA 417 PA P AP +P P +P P+P P A + P P +P AP +P Sbjct: 559 EPAPTTPKEPAPTTPKKPAPTTP-KEPAPTTPKEPAPTTTKKP--APTTPKEPAPTTPKE 615 Query: 418 SPPVSPS----ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP--PLAAPPL 471 + P +P TP AP + P P + P P+ T P + P P AA P Sbjct: 616 TAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPN 675 Query: 472 QLAKPPPQAP--PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529 +P P P PA TP A +P + P + +L TP AP LA Sbjct: 676 TPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735 Query: 530 PLLQVPPSP------PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 + P S P +P AP P P P T P P P +P+ T Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKE---------PAPTTPKGTAPT-T 785 Query: 584 LSGPDLAGHSSSATSTPEELRGYDS-GPEGGAAASPPPDA--ELAACHPAAWSRGPAPPL 640 L P ++ P+EL + GP + P P E A P + PAP Sbjct: 786 LKEP---APTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTP----KEPAPT- 837 Query: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPE-------------SATPAPGALDPGP 687 P P P P T P + + T T+ P SA P P AL+ P Sbjct: 838 ----TPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSP 893 Query: 688 -SPGTSGGKAAA 698 PG K A Sbjct: 894 KEPGVPTTKTPA 905 Score = 114 bits (284), Expect = 5e-25 Identities = 121/543 (22%), Positives = 183/543 (33%), Gaps = 55/543 (10%) Query: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR----------PSAGGGLQ 226 EV P PS++ PP G +++ S ++ S P+ ++ S + Sbjct: 106 EVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQE 165 Query: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286 +S S SSS++ + S SA + K +P P +A Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSG 225 Query: 287 L-----------------GPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 L +S+SP T + P PS PP+ T T + T Sbjct: 226 LDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVE 285 Query: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389 T + + A ++ + +P LA P+P+A Sbjct: 286 TKETTTTNKQTSTDG---------KEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 336 Query: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 L P P P+ P + P ++ P P+ T AP + P S P + Sbjct: 337 TTTKGPALTTPKEPTPTTPKE----PASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 392 Query: 450 P-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 P +P+ T P P P +P P + T P + P+ P P P+ Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452 Query: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSP-PASPTLQAPRRPPTPGPDTSVSGPRLTLA 567 + P P T P + P P P P P +P AP P P P T+ P T Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP-TTPKEPAPTTT 511 Query: 568 LAPGPPPPPSRSPSSTLSGPDLAGH-----SSSATSTPEE------LRGYDSGPEGGAAA 616 P P P +P++T S P + SA +TP+E + P+ A Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571 Query: 617 SPPPDAELAACHPAAWS-RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 675 +P A PA + + PAP + AP P P T +A PE Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 631 Query: 676 ATP 678 P Sbjct: 632 LAP 634 Score = 96.7 bits (239), Expect = 8e-20 Identities = 142/603 (23%), Positives = 204/603 (33%), Gaps = 68/603 (11%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 K A + PA AP P P P P P PA + ++P A Sbjct: 472 KEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEP-APTTTKSA 530 Query: 67 GATIPESAP---RAGPTRTSRPPASGRGERAP-----PAKNTSPGPV-SSPGRASGTT-- 115 T E AP ++ PT P + E AP PA T P ++P + TT Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP---TPGTPS-PAMARRS 171 P P K T + A PK +A + + + P P TP PA Sbjct: 591 EPAPTTTK----KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646 Query: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231 A T P P P P T +A+ ++ EP+P + P A + PA Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTP------KAAAPNTPKEPAPTTPKEP-APTTPKEPAPT 699 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291 + +A ++P + P+ P AP P +P PK L + T D P Sbjct: 700 TPKETAP--TTPKGTAPTTLKEP-APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756 Query: 292 SSPLAT--PSPSAP--PSPSAPPSLQ--TLPSP-PATPPSQATTSLGSPTLQ---ATHSF 341 ++P P+P+ P P+P+ P TL P P TP A L T + +T S Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816 Query: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 P+P P PA P AP +P PP + + +H Sbjct: 817 KPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDES 876 Query: 402 SPPPS--PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV--------PPSPPASPP 451 +P S P +A + P P V + TP + P + P + A+P Sbjct: 877 TPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK 936 Query: 452 MSP--SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--- 506 M+ + T + A Q+ Q L+ P + + Sbjct: 937 MTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTE 996 Query: 507 ----------PSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-PTLQAPRRPPTPGP 555 P S TP PQ P AP P + P ++ P+ PTP Sbjct: 997 IMNKPEETAKPKDRATNSKATTPKPQKPT--KAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054 Query: 556 DTS 558 TS Sbjct: 1055 MTS 1057 >gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo sapiens] Length = 5537 Score = 145 bits (367), Expect = 1e-34 Identities = 209/797 (26%), Positives = 275/797 (34%), Gaps = 122/797 (15%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK---------- 56 KA+ G R+ A + + + P P P P AL V G Sbjct: 351 KAQGGQTIRSVAEQHTPVCSRFSPPEPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPG 410 Query: 57 PLAERAGGIGGATIPESAPRAGPTRTSRP--PASGRGERAPPAKNTSPGPVSSPGRASGT 114 PL A +G A + P P P +PP + + P R S Sbjct: 411 PLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPP 470 Query: 115 TRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAA 174 P + + + P+ S LS P P + + S + Sbjct: 471 PEELPASPLPEALHLSRPLEESPLSPPPEESPLS---------PPPESSPFSPLEESPLS 521 Query: 175 GTEVGLPRPAPSARPRPPTEGPRKS-------VSSASEHSTTEPSPAARRRPSAGGGLQR 227 E P PA PP E S +S E T P P A R L Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASR-------LSP 574 Query: 228 PASRSLSSSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQ---VTPPRKDA 283 P S S P SP P A R P P P P+ PP+ ++PP +D Sbjct: 575 PPEES-PMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPED- 632 Query: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLP---SPPATPPSQATTSLGSPTLQATHS 340 +P P SP++ P + SP S + P SP + PP ++ T SP +A+ Sbjct: 633 SPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPT---SPPPEASR- 688 Query: 341 FLPSPPLSPLATPP---PQAPP----ALALPPLQAPPSP-PASPPLSPLATPSPQAPNAL 392 P P SP + PP P +PP ++LP ++P P P P L P + +P Sbjct: 689 LSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPE 748 Query: 393 AVHLLQAPFSPPPSPPVQAP-FSP----------PASPPVSPSATPPSQAP--------P 433 HL P P SP + P SP P P +SP A P +P P Sbjct: 749 EPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSP 808 Query: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 P L P P P + PQ+ P +P P L PPL P Sbjct: 809 QTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSP----RPEESHLSPELEKPPLSPRP 864 Query: 494 SPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551 P PGQ P LP+ P PP P P+L P L P PP SP P Sbjct: 865 EKPPEEPGQCP--APEELPLFP---PPGEPSLSPLLGEPALSEPGEPPLSPL-------P 912 Query: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611 P + P L+ L P P PP SP T + P A P +G DS PE Sbjct: 913 EELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPP-ALSPLGELEYPFGAKG-DSDPE 970 Query: 612 GGAAA-------SPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL---------PWPPA 655 AA SPPP+A P PP+ +PG+P+ P PP Sbjct: 971 SPLAAPILETPISPPPEANCT-------DPEPVPPMILPPSPGSPVGPASPILMEPLPPQ 1023 Query: 656 TGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715 P L + + P +P P PSP + GK G A + ++ Sbjct: 1024 CSPLLQHSL--VPQNSPPSQCSP-PALPLSVPSPLSPIGK-VVGVSDEAELHEMETEKVS 1079 Query: 716 ELPLGALQASVVQHLLS 732 E AL+ S L S Sbjct: 1080 EPECPALEPSATSPLPS 1096 Score = 131 bits (329), Expect = 3e-30 Identities = 194/724 (26%), Positives = 242/724 (33%), Gaps = 144/724 (19%) Query: 16 TPAARAPGLLTPRPPGSPRPPP----PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 +PA P L+P P SP PP P++P P Sbjct: 529 SPALETP--LSPPPEASPLSPPFEESPLSPP----------------------------P 558 Query: 72 ESAPRAGPTRTSR--PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129 E P + P SR PP E +P + P+S P AS P + L Sbjct: 559 EELPTSPPPEASRLSPPP----EESPMSPPPEESPMSPPPEASRLFPP--FEESPLSPPP 612 Query: 130 EETVARGKATEAPKRSALSAGARRDTSGP----TPGTPSPAMARRSRAAGTEVGLPRPAP 185 EE+ + P+ S LS P +P +P P ++R S P P Sbjct: 613 EES----PLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEE 668 Query: 186 SARPRPPTEGPRKSVSSAS------EHSTTEP----SPAARRRPSAGGGLQRPASRSLSS 235 S PP E P AS E S T P SPA+ + L S L Sbjct: 669 SPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLPL 728 Query: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGL--QALRP---PQVTPPRKDAAPA---L 287 P P GP P P +P+ L QA P PQ P A P L Sbjct: 729 PEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHL 788 Query: 288 GPLSSSPLATPSPSAPP-SPSAP-PSLQTLPSPPATPPSQATTSLG--------SPTLQA 337 P + P +P P SP P L +P P P + L SP + Sbjct: 789 SPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEE 848 Query: 338 THSF--LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395 +H L PPLSP PP+ P P PP P LSPL L Sbjct: 849 SHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPL----------LGEP 898 Query: 396 LLQAPFSPPPSP-PVQAPFSPPASPPVSPSATPPSQAPPSL------AAPPL-------- 440 L P PP SP P + P SP P +SP PP PP L AAPP Sbjct: 899 ALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGELE 958 Query: 441 --------QVPPSPPASPPMSPSATPPPQAP-------PPLAAPPLQLAKPPPQAPPALA 485 P SP A+P + +PPP+A PP+ PP + P +P + Sbjct: 959 YPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME 1018 Query: 486 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP--PVLA----APLLQVPP--- 536 P Q P S Q S P PL+ P P +P V+ A L ++ Sbjct: 1019 PLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKV 1078 Query: 537 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS-----RSPSSTLSGPDLAG 591 S P P L+ P P P +S P AP P P ++ L G D G Sbjct: 1079 SEPECPALEPSATSPLPSPMGDLSCP------APSPAPALDDFSGLGEDTAPLDGIDAPG 1132 Query: 592 HSSSATSTP----EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 647 TP EL+G + A P C A P AP Sbjct: 1133 SQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYPECKQTAGQGSPCEEQEEPRAPV 1192 Query: 648 APLP 651 AP P Sbjct: 1193 APTP 1196 Score = 113 bits (283), Expect = 6e-25 Identities = 219/848 (25%), Positives = 295/848 (34%), Gaps = 125/848 (14%) Query: 48 GAAGAVGRKPLAERA---GGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGP 104 G G G + +R GG+ +P S+P + P ER + PG Sbjct: 1910 GTPGLEGSRTPLQRPFLQGGLPLGNLPSSSPMDSYPGLCQSPFLDSRERGG-FFSPEPGE 1968 Query: 105 VSSPGRASGTTRPG----PLGQ---KGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157 SP SG T P P + GL + K E + S +S + + Sbjct: 1969 PDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQRWEKDEELGQLSTISPVLYANINF 2028 Query: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217 P P + R + + L R P+A P + + + ++ + + + + Sbjct: 2029 PNLKQDYPDWSSRCKQI---MKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQAESQIN 2085 Query: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-----SQPKPKGLQA-- 270 + + G + R R A L P + P A G+P A P S P GL Sbjct: 2086 KQTKVGDIARKTDRP----ALHLRIPPQ--PGALGSPPPAAAPTIFIGSPTTPAGLSTSA 2139 Query: 271 ---LRPPQVTPPRKDA-----------APALGPLSSSP--LATPSPSAPPSPSAPPSLQT 314 L+PP + P D+ PA P S P LA P P P+APP+ Sbjct: 2140 DGFLKPPAGSVPGPDSPGELFLKLPPQVPAQVP-SQDPFGLAPAYPLEPRFPTAPPTYPP 2198 Query: 315 LPSP---PATPPSQATTSL-GSPTLQATHSFLPSPPLSPLATPPPQAPPAL-ALPPLQAP 369 PSP PA PP +S G+ H+ P P +TP P P +L L P Sbjct: 2199 YPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVP 2258 Query: 370 PSPPAS--PPLSPLATPSPQAPNALAVHLLQAPF---SPPPSPPVQAPFSPPAS------ 418 SP PL +P P + A+ + + SP PP P+S Sbjct: 2259 ESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGG 2318 Query: 419 ----------PPVSPSATPPSQAPPSLAAPPLQVPPSPPA--SPPMSPSATPPPQAPPPL 466 P++P A+ P L P + PP+ SPP P P P Sbjct: 2319 LELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPY 2378 Query: 467 AAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV 526 A PPL P PQ P PP PP S P PFS + P S ++ P P Sbjct: 2379 AQPPL---TPRPQPP-----PPESCCALPPRSLPSD-PFSRVPASPQSQSSSQSPLTPRP 2429 Query: 527 LAAPLLQVPPSPPASPTLQAP---RRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583 L+A PS P +P Q+P RPP S P+ AP PP + P Sbjct: 2430 LSAEAF--CPS-PVTPRFQSPDPYSRPP--------SRPQSRDPFAPLHKPPRPQPPEVA 2478 Query: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP-PLAF 642 LA S A P L +G S P + + A+ P+P F Sbjct: 2479 FKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTF 2538 Query: 643 RGAPGAPLPWPPATGPG--SADGLCTIY---ETEG-PESA--TPAPGALDPGPSP-GTSG 693 A G P PP PG G+ + + T G P+S T A G P SP G S Sbjct: 2539 PQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSS 2598 Query: 694 GKAAAGAGAG---ASSRSPKQARLGELPL---GALQASVVQHLLSRTLLLAAAEGAAGGS 747 G G S P A G LP GA Q S + T + E G Sbjct: 2599 GSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGI------TSPVEKREDPGTGM 2652 Query: 748 GGGPGGAEGGGVTGGARAALSDAEL------GRWAELLSPLDESRASI--TSVTSFSPDD 799 G AE G + LS EL R ELL R ++ T+ + Sbjct: 2653 GSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAG 2712 Query: 800 VASPQGDW 807 P G W Sbjct: 2713 AVGPPGSW 2720 Score = 87.0 bits (214), Expect = 6e-17 Identities = 199/788 (25%), Positives = 261/788 (33%), Gaps = 121/788 (15%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE-----R 61 + K G AR A L P PG+ PPP + + G A+ Sbjct: 2087 QTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSADGFLKPP 2146 Query: 62 AGGIGG--------ATIPESAPRAGPTR-----TSRPPASGRGERAPPAKNTSPGPVSSP 108 AG + G +P P P++ P R APP P P +P Sbjct: 2147 AGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSPTGAP 2206 Query: 109 GR---ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSP 165 + ++RPG GQ G T G P R P + Sbjct: 2207 AQPPMLGASSRPG-AGQPG----EFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNL 2255 Query: 166 AMARRSRAAGTEVGLP--RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG- 222 A+ G + P P P R E +K AS S P+ PS+G Sbjct: 2256 AVPESPGVGGGKASEPLLSPPPFGESRKALE-VKKEELGASSPSYGPPNLGFVDSPSSGT 2314 Query: 223 --GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRP-PQVTPP 279 GGL+ + TP +S +P P +P P QAL P P P Sbjct: 2315 HLGGLELKTPDVFKAPLTPRASQVEP-----QSPGLGLRPQEPPP--AQALAPSPPSHPD 2367 Query: 280 RKDAAPALGPLSSSPLATPSPSAPPSPSA---PPSLQTLPSP-----PATPPSQATT-SL 330 P + PL TP P PP S PP ++LPS PA+P SQ+++ S Sbjct: 2368 IFRPGSYTDPYAQPPL-TPRPQPPPPESCCALPP--RSLPSDPFSRVPASPQSQSSSQSP 2424 Query: 331 GSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS-PPLSPL-ATPSPQA 388 +P + +F PSP TP Q+P P PPS P S P +PL P PQ Sbjct: 2425 LTPRPLSAEAFCPSP-----VTPRFQSP-----DPYSRPPSRPQSRDPFAPLHKPPRPQP 2474 Query: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP----LQVPP 444 P V + P + PA P A PS PP+ P P Sbjct: 2475 PE---VAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTP 2531 Query: 445 SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA-------PPALATPPLQALPSPPA 497 SP P A P PP+ P L PPP P L P Sbjct: 2532 SPMRF--TFPQAVGEPSLKPPVPQPGL----PPPHGINSHFGPGPTLGKPQSTNYTVATG 2585 Query: 498 SF-PGQAPFSPSA-----SLPMSPLATP---PPQAPPVLAAPLLQVPPSPPASPTLQAPR 548 +F P +P PS+ S +SPL P PP AP + P L S + T + Sbjct: 2586 NFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG-SLPYLSHGASQRSGITSPVEK 2644 Query: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608 R P T + G L A PG P S T ++++ Sbjct: 2645 R---EDPGTGM-GSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTL 2700 Query: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 668 E AA+ A A P +W P+ P AF P+ S GL Sbjct: 2701 RQEKETAAA----AAGAVGPPGSWGAEPSSP-AFEQLSRGQTPFAGTQDKSSLVGL-PPS 2754 Query: 669 ETEGP---ESATPAPGALDPGPSPGTS-----GGKAAAGAGAGASSRSPKQARLGELPLG 720 + GP + P+ L P P T + G R+P G LPL Sbjct: 2755 KLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP---GSLPLQ 2811 Query: 721 ALQASVVQ 728 Q + Q Sbjct: 2812 QQQQQLWQ 2819 Score = 69.7 bits (169), Expect = 1e-11 Identities = 153/656 (23%), Positives = 217/656 (33%), Gaps = 121/656 (18%) Query: 75 PRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 134 PRA P R + PPA+ +P P S P + P Q L + Sbjct: 2333 PRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPP 2392 Query: 135 RGKATEAPKR------SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 P+ S + A + +S +P TP P A + P P +R Sbjct: 2393 ESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSR 2452 Query: 189 P--RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246 P RP + P A H P P P A SL + P + PA Sbjct: 2453 PPSRPQSRDP-----FAPLHKPPRPQP-----PEVAFKAGSLAHTSLGAGGFPAALPA-- 2500 Query: 247 GPSARGTPRAPAH--PSQPKPKGLQAL----RPPQVTPPRKDAAPALGPLSSSPLATPSP 300 GP+ + P+ P+ + G A P + T P+ P+L P P P P Sbjct: 2501 GPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQP-GLPPP 2559 Query: 301 SAPPSPSAPPSLQTLPSPPATPPSQATTSL---GSPTLQATHSFLPSPPLSPLATP---P 354 S P TL P +T + AT + GSP ++ S S LSPL P P Sbjct: 2560 HGINSHFGPGP--TLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLP 2617 Query: 355 PQAPPALALPPLQAPPSPPA--SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ-- 410 P AP +LP L S + + P+ P ++LA L P S Q Sbjct: 2618 PPAPDG-SLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTE 2676 Query: 411 -------------------------------APFSPPASPPVSPSATPPSQAPPSLA--- 436 A + PP S A P S A L+ Sbjct: 2677 LEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQ 2736 Query: 437 ---------APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATP 487 + + +PPS + P + P + P +L++PPP A P+ Sbjct: 2737 TPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDD----------RLSRPPPPATPSSMDV 2786 Query: 488 PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP--PASPTLQ 545 + L +F +AP+ SLP+ Q AA ++ S P++P + Sbjct: 2787 NSRQLVGGSQAFYQRAPY--PGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPE 2844 Query: 546 APRR----------PPTPGPDTSVSGP-----------RLTLALAPGPPPPPSRSPSSTL 584 R+ PGP V GP + L PG P P + P Sbjct: 2845 LGRQALGSPLAGISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRP 2904 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL-AACHPAAWSRGPAPP 639 ++ PE LRG S PP EL + HP ++GP P Sbjct: 2905 RFYPVS--EDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958 Score = 69.7 bits (169), Expect = 1e-11 Identities = 131/542 (24%), Positives = 174/542 (32%), Gaps = 98/542 (18%) Query: 17 PAARAPGLLTPRPPGSP--RPPPPVTPAALRVLGAAG----AVGRKPLAERAGGIGGATI 70 P +R P R P +P +PP P P G+ G P A AG G + Sbjct: 2449 PYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAG--EL 2506 Query: 71 PESAPRAGPTRTSRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPG----------- 118 P P R P +G P P + T P V P +PG Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHF 2566 Query: 119 -PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP---------GTPSPAMA 168 P G S TVA G + S+G+ ++ G +P P ++ Sbjct: 2567 GPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLP 2626 Query: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 S A G+ P + P G S+++A T +P + + QR Sbjct: 2627 YLSHGASQRSGITSPVE--KREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQ 2684 Query: 229 ASRSL----SSSATPLSSPARSGPSARGTPRAP----AHPSQPKPKGLQALRPPQV---- 276 R L L + +A G P A PS P + L + P Sbjct: 2685 RLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQD 2744 Query: 277 ------TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL---------------QTL 315 PP K + P LGP S P + S PP P+ P S+ Q Sbjct: 2745 KSSLVGLPPSKLSGPILGP-GSFP-SDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRA 2802 Query: 316 PSPPATPPSQATTSLGSP-----------TLQATHSFLPSPPLSPLATPPPQAPPALALP 364 P P + P Q L + A P P L A P A + LP Sbjct: 2803 PYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLAGISTRLP 2862 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP-PVQAPFSPPASPPVSP 423 P PA P A H +Q P +P P Q P P PVS Sbjct: 2863 GPGEPVPGPAGP-----------AQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSE 2911 Query: 424 SATPPSQAPPSL-----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 P AP L + P Q P +PPA P ++ S P P P L+L PP Sbjct: 2912 D--PHRLAPEGLRGLAVSGLPPQKPSAPPA-PELNNSLHPTPHTKGPTLPTGLELVNRPP 2968 Query: 479 QA 480 + Sbjct: 2969 SS 2970 Score = 67.0 bits (162), Expect = 7e-11 Identities = 103/387 (26%), Positives = 137/387 (35%), Gaps = 64/387 (16%) Query: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGT-PRAPA------HPS-------------- 261 G Q ++SS AT S + GP A GT P + A PS Sbjct: 4023 GKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQP 4082 Query: 262 QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT 321 QP+P LQ L+PP P ++ +L L ++ + S S S+ L + P+ Sbjct: 4083 QPQPSSLQ-LQPPLRLPGQQQQQVSL--LHTAGGGSHGQLGSGSSSEASSVPHLLAQPSV 4139 Query: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381 S+ L L P + PP+ P L Q P P + L Sbjct: 4140 SLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSG--QGLPGVGIMPTVGQL 4197 Query: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-PASPPVSPSATPPSQAPPSLAAP-- 438 Q LA + SP +QA + TPP Q P + +P Sbjct: 4198 RA---QLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQ 4254 Query: 439 -------PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 491 L P P P A P PQ PP L APP L+ P P Sbjct: 4255 GLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGP---------V 4305 Query: 492 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551 P+PP S P Q P PS LP SP + P +A Q+PP+ P +P Q P P Sbjct: 4306 HPTPPPSSP-QEPKRPS-QLP-SPSSQLPTEA---------QLPPTHPGTPKPQGPTLEP 4353 Query: 552 TPG----PDTSVSGPRLTLALAPGPPP 574 PG ++ + L P PP Sbjct: 4354 PPGRVSPAAAQLADTLFSKGLGPWDPP 4380 Score = 66.6 bits (161), Expect = 9e-11 Identities = 150/672 (22%), Positives = 221/672 (32%), Gaps = 135/672 (20%) Query: 16 TPAARAP--GLLTPRPPGSPRP------PPP--VTPAALRVLGAAGAVGRKP------LA 59 +P+++ P L P PG+P+P PPP V+PAA ++ + G P LA Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384 Query: 60 E------------RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS 107 E + G +PE++ + P + + N P+ + Sbjct: 4385 ETQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGE--PIGA 4442 Query: 108 PGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAM 167 PG ++ GP + G + + + R K + S G R + +G Sbjct: 4443 PGTSNHLLLAGPRSEAGHLLL--QKLLRAKNVQLSTGRG-SEGLRAEINGHID------- 4492 Query: 168 ARRSRAAGTE---VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224 S+ AG E G P A R P K V AS+ S + R G Sbjct: 4493 ---SKLAGLEQKLQGTPSNKEDAAARKPLTPKPKRVQKASDRLV---SSRKKLRKEDGVR 4546 Query: 225 LQRPASRSLSS--SATPLSSPARSGPSARGTPRAPAHP--SQPKPKGLQALRPPQVTPPR 280 + L S PL+ PA + + P P Q + +G P Sbjct: 4547 ASEALLKQLKQELSLLPLTEPAITANFSLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDY 4606 Query: 281 KDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATP-------PSQATTSLGSP 333 LS+ P TP S PP+P PPS+Q TP P A ++ S Sbjct: 4607 YSQLLTKNNLSNPP--TPPSSLPPTP--PPSVQQKMVNGVTPSEELGEHPKDAASARDSE 4662 Query: 334 -TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP----PASPPLSPLATPSPQA 388 L+ T L+ L TPP + + + SP PAS P S L +P+ Sbjct: 4663 RALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPRF 4722 Query: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 448 P+ + Q + P P+ S P P P + P L + Sbjct: 4723 PHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEV 4782 Query: 449 SPPMSPSATPPPQAPPPL-AAPPLQLAKPP-------PQAPPALATPPLQALPSPP---- 496 S ++ SA + A L K P P++P T P + P Sbjct: 4783 SVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKE 4842 Query: 497 -------------------ASFPG-----------------QAPFSPS--------ASLP 512 A PG AP P+ ++L Sbjct: 4843 KGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLD 4902 Query: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAP----RRPPTPGPDTSVSGPRLTLAL 568 + L+ PPP+ P +PL P SPP P ++ P PP P P S P Sbjct: 4903 VRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPE----- 4957 Query: 569 APGPPPPPSRSP 580 P P +R P Sbjct: 4958 -SARPKPRARPP 4968 Score = 61.6 bits (148), Expect = 3e-09 Identities = 139/564 (24%), Positives = 189/564 (33%), Gaps = 120/564 (21%) Query: 117 PGPLGQKGLRISAEETVA----RGKATEAPKR---SALSAGARRDTSGPTPGTPSPAMAR 169 PG LG L E+ +ATE P L+ G ++ PG P+++ Sbjct: 4012 PGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSG 4071 Query: 170 RSRAAGTEVGLPRPAPSA-RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 S+ + P+P PS+ + +PP P + S T AGGG Sbjct: 4072 DSQLLLVQPQ-PQPQPSSLQLQPPLRLPGQQQQQVSLLHT------------AGGGSHGQ 4118 Query: 229 ASRSLSSSATP----LSSPARSGPSARGTPR----APAHPSQPKP-KGLQALRPPQVTP- 278 SS A+ L+ P+ S G+ P P +P + +PP+ P Sbjct: 4119 LGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPV 4178 Query: 279 -------PRKDAAPALGPLSSS---PLATPSPSAPPSPSAPPSLQTL------------- 315 P P +G L + LA SP LQ L Sbjct: 4179 LQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVR 4238 Query: 316 PSPPATPPSQATTSL-GSPTLQATHSFLPSPPLSPL----ATPPPQAPPALALPPLQAPP 370 +PP P T+ L G Q P P PL A P PQ PP L P Sbjct: 4239 QTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRL--------P 4290 Query: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ 430 +PP + P+ P VH +PPPS P + P P PS P SQ Sbjct: 4291 APPGALSTGPVLGP---------VHP-----TPPPSSPQE-----PKRPSQLPS--PSSQ 4329 Query: 431 APPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL 489 P Q+PP+ P +P P P+ PPP P AA Q L + L Sbjct: 4330 LPTE-----AQLPPTHPGTPKPQGPTLEPPPGRVSPAAA----------QLADTLFSKGL 4374 Query: 490 QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR 549 P Q P S+ +P P + Q P P + Q+ +R Sbjct: 4375 GPWDPPDNLAETQKP-EQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKR 4433 Query: 550 ----PPTPGPDTS----VSGPR------LTLALAPGPPPPPSRSPSSTLSGPDLAGH-SS 594 P P TS ++GPR L L S S ++ GH S Sbjct: 4434 EANGEPIGAPGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDS 4493 Query: 595 SATSTPEELRGYDSGPEGGAAASP 618 ++L+G S E AA P Sbjct: 4494 KLAGLEQKLQGTPSNKEDAAARKP 4517 Score = 54.3 bits (129), Expect = 4e-07 Identities = 73/311 (23%), Positives = 111/311 (35%), Gaps = 37/311 (11%) Query: 101 SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE---APKRSALSAGARRDTSG 157 S G + S + ++ P L Q + + + G T+ P++ L + +T G Sbjct: 4115 SHGQLGSGSSSEASSVPHLLAQPSVSLGDQP----GSMTQNLLGPQQPMLERPMQNNT-G 4169 Query: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP---TEGPRKSVSSASEHSTTEPSPA 214 P P P P + G VG+ R + + P+ S + + Sbjct: 4170 PQPPKPGPVLQSGQGLPG--VGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227 Query: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-----PKPKGLQ 269 R+ + Q P + + +PL P G P P Q P+P+G Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQG-- 4285 Query: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS 329 PPR A P G LS+ P+ P P+ PPS P P+ PS ++ Sbjct: 4286 --------PPRLPAPP--GALSTGPVL-----GPVHPTPPPSSPQEPKRPSQLPSPSSQL 4330 Query: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALA--LPPLQAPPSPPASPPLSPLATPSPQ 387 L TH P P L PP + PA A L + P PP + T P+ Sbjct: 4331 PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPE 4390 Query: 388 APNALAVHLLQ 398 + + HL Q Sbjct: 4391 QSSLVPGHLDQ 4401 Score = 53.9 bits (128), Expect = 6e-07 Identities = 109/429 (25%), Positives = 144/429 (33%), Gaps = 74/429 (17%) Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA----- 357 P P+ P LQ SP A P+ T T+ P +S AT P Sbjct: 3999 PGMPAKP--LQHFSSPGALGPTLLLTGKEQNTVD--------PAVSSEATEGPSTHQGGP 4048 Query: 358 ------PPALALPPLQAPPSPPASPPLSPLATPSPQA-PNALAVHLLQAPFSPPPSPPVQ 410 P ++A P + PS L L P PQ P++L LQ P P Q Sbjct: 4049 LAIGTTPESMATEPGEVKPSLSGDSQLL-LVQPQPQPQPSSLQ---LQPPLRLPGQQQQQ 4104 Query: 411 APFSPPASPPV-----SPSATPPSQAPPSLAAPPLQVPPSPPASP-----PMSPSATPPP 460 A S S++ S P LA P + + P + P P P Sbjct: 4105 VSLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPM 4164 Query: 461 Q----APPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPMSP 515 Q PP P LQ + P L+A L A P SP + Sbjct: 4165 QNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQA 4224 Query: 516 LA-------------TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP 562 L TPP Q P +PL + P PGP T GP Sbjct: 4225 LLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGF--------PGPQT---GP 4273 Query: 563 RLTLALAPGPPPPPS--RSPSSTLSGPDLAG-HSSSATSTPEELRGYDSGPEGGAAASPP 619 L P P PP P + +GP L H + S+P+E + P ++ P Sbjct: 4274 LQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPS--PSSQLP 4331 Query: 620 PDAELAACHPAAWS-RGPA---PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPES 675 +A+L HP +GP PP A + G G D + ET+ PE Sbjct: 4332 TEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQ 4391 Query: 676 ATPAPGALD 684 ++ PG LD Sbjct: 4392 SSLVPGHLD 4400 Score = 53.9 bits (128), Expect = 6e-07 Identities = 35/96 (36%), Positives = 43/96 (44%), Gaps = 17/96 (17%) Query: 383 TPSPQAPNA---------LAVHLLQAPF----SPPPSPPVQAPFSPPASP----PVSPSA 425 +P+P+ P L V L AP SPPPSP +P SPP P P P A Sbjct: 4883 SPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLA 4942 Query: 426 TPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 PP +P LA+ P P P A PP + PP+ Sbjct: 4943 EPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPR 4978 Score = 47.0 bits (110), Expect = 7e-05 Identities = 168/743 (22%), Positives = 227/743 (30%), Gaps = 139/743 (18%) Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86 PRP G PR P P P AL G V P P S+P+ P R S+ P Sbjct: 4281 PRPQGPPRLPAP--PGALSTGPVLGPVHPTP-------------PPSSPQE-PKRPSQLP 4324 Query: 87 ASGRG----ERAPPAKNTSPGPVSS-----PGRASGTTRP--GPLGQKGLRI-SAEETVA 134 + + PP +P P PGR S L KGL + +A Sbjct: 4325 SPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA 4384 Query: 135 RGKATEAPKRSALSAGARRDTSGPT-PGTPSPAMARRSR----AAGTEV------GLPRP 183 T+ P++S+L G +G P ++ + R A G + G P Sbjct: 4385 E---TQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANGEPIG 4441 Query: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 AP GPR GL+ + + S L Sbjct: 4442 APGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQK 4501 Query: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRK-------DAAPAL-----GPLS 291 + PS + A P PKPK +Q V+ +K A+ AL LS Sbjct: 4502 LQGTPSNK-EDAAARKPLTPKPKRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELS 4560 Query: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351 PL P+ +A S AP P SQ + GS L Sbjct: 4561 LLPLTEPAITANFSLFAPFG----SGCPVNGQSQLRGAFGS---------------GALP 4601 Query: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNA------LAVHLLQAPFSPPP 405 T P L L PP+PP+S P +P + + N L H A + Sbjct: 4602 TGPDYYSQLLTKNNLSNPPTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDS 4661 Query: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQ 461 ++ + ++ TPP + + SP PAS P S P+ Sbjct: 4662 ERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGEEAPR 4721 Query: 462 AP---------PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP----- 507 P A P+ P P T P AL PG+ P + Sbjct: 4722 FPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGAL---GLEVPGKLPVTTWEKGK 4778 Query: 508 ----SASLPMSPLATPPPQAPPVLAAPLLQV----------PPSPPASPTLQAPRRPPTP 553 S L +S A V A LL + P SP + T P++ Sbjct: 4779 GSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGT--EPKKGEAE 4836 Query: 554 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGH--------SSSATSTPEELRG 605 GP G +P P + + L G L S P Sbjct: 4837 GPGGKEKGLE---GKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHS 4893 Query: 606 YD---SGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSAD 662 Y S + ++PPP+ P A S P P PL PP P Sbjct: 4894 YTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP---- 4949 Query: 663 GLCTIYETEGPESATPAPGALDP 685 + PESA P P A P Sbjct: 4950 ----LPLASSPESARPKPRARPP 4968 Score = 39.7 bits (91), Expect = 0.011 Identities = 105/458 (22%), Positives = 139/458 (30%), Gaps = 117/458 (25%) Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVT--PAALRVLGAAGAV--GRKPLAERAGGIG 66 G + P PGL P S P P P + A G PL +G G Sbjct: 2543 GEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTG 2602 Query: 67 GA----------TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRAS---- 112 + +P AP S + G +P K PG A+ Sbjct: 2603 ESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662 Query: 113 GTTRPGPLG------------QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTP 160 GT PG G Q+ + + + R + + +A +AGA Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722 Query: 161 GTPSPAMARRSRA----AGTE-----VGLP---------------------RPAPSARPR 190 SPA + SR AGT+ VGLP RP P A P Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPS 2782 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAA------------RRRPSAGGGLQRPASRSLSSSAT 238 R+ V + P P + +++ +A ++ S S+ Sbjct: 2783 SMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPG 2842 Query: 239 P-LSSPARSGPSARGTPRAPAHPSQPKP----------------KGL-------QALRPP 274 P L A P A + R P P +P P KGL PP Sbjct: 2843 PELGRQALGSPLAGISTRLPG-PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPP 2901 Query: 275 Q-------VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Q P + A L L+ S L PSAPP+P SL P Sbjct: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTK-------- 2953 Query: 328 TSLGSPTLQATHSFLPSPPLS-PLATPPPQAPPALALP 364 PTL + PP S L P P A A LP Sbjct: 2954 ----GPTLPTGLELVNRPPSSTELGRPNPLALEAGKLP 2987 Score = 37.7 bits (86), Expect = 0.043 Identities = 73/298 (24%), Positives = 96/298 (32%), Gaps = 51/298 (17%) Query: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP-LQLAKPP 477 P VS AT + P + PL + +P + AT P + P L+ L L +P Sbjct: 4031 PAVSSEAT---EGPSTHQGGPLAIGTTPESM------ATEPGEVKPSLSGDSQLLLVQPQ 4081 Query: 478 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM---------SPLATPPPQAPPVLA 528 PQ P+ LQ PP PGQ S S ++ P +LA Sbjct: 4082 PQPQPS----SLQL--QPPLRLPGQQQQQVSLLHTAGGGSHGQLGSGSSSEASSVPHLLA 4135 Query: 529 APLLQVPPSP---------PASPTLQAPRR------PPTPGPDTSVSGPRLTLALAPGPP 573 P + + P P P L+ P + PP PGP + + P Sbjct: 4136 QPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVG 4195 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA-CHPAAW 632 ++ P L S + L + A PP E P Sbjct: 4196 QLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQG 4255 Query: 633 SRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690 G P L G PG P TGP G +GP PGAL GP G Sbjct: 4256 LLGCQPQLG--GFPG------PQTGPLQELGAGP--RPQGPPRLPAPPGALSTGPVLG 4303 Score = 35.8 bits (81), Expect = 0.16 Identities = 62/274 (22%), Positives = 88/274 (32%), Gaps = 50/274 (18%) Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRP-------------GPLGQKGLRISAEET 132 P S GE AP + G RA P P G GL + + Sbjct: 4711 PESILGEEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVFPDTKPYGALGLEVPGKLP 4770 Query: 133 VA---RGKATEAPKRSALSAGARRDTSG------------------------PTPGTPSP 165 V +GK +E +SA A ++ +G P P Sbjct: 4771 VTTWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEP 4830 Query: 166 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL 225 G E GL +P P + + S + P+ Sbjct: 4831 KKGEAEGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPT 4890 Query: 226 QRPASRSLSS-SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAA 284 Q + ++S+ LS+P PS +P AP+ S P ++ P PP Sbjct: 4891 QHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPP----V 4946 Query: 285 PALGPLSSSP-LATPSPSAPP----SPSAPPSLQ 313 P+ PL+SSP A P P A P S PP L+ Sbjct: 4947 PSPLPLASSPESARPKPRARPPEEGEDSRPPRLK 4980 Score = 32.7 bits (73), Expect = 1.4 Identities = 28/83 (33%), Positives = 34/83 (40%), Gaps = 8/83 (9%) Query: 282 DAAPALGPLSSSPLATPSPSAPPSPSAPPS--LQTLPSPP-ATPPSQATTSLGSPTLQAT 338 D P P PSP AP SP++PP+ L LP+ P A PP + L S + Sbjct: 4902 DVRQLSAPPPEEPSPPPSPLAP-SPASPPTEPLVELPTEPLAEPPVPSPLPLAS----SP 4956 Query: 339 HSFLPSPPLSPLATPPPQAPPAL 361 S P P P PP L Sbjct: 4957 ESARPKPRARPPEEGEDSRPPRL 4979 Score = 32.7 bits (73), Expect = 1.4 Identities = 27/80 (33%), Positives = 35/80 (43%), Gaps = 9/80 (11%) Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER--AGGIGGATIPESAPRAG 78 AP P PP SP P P +P ++ + +PLAE + A+ PES A Sbjct: 4908 APPPEEPSPPPSPLAPSPASPPTEPLV----ELPTEPLAEPPVPSPLPLASSPES---AR 4960 Query: 79 PTRTSRPPASGRGERAPPAK 98 P +RPP G R P K Sbjct: 4961 PKPRARPPEEGEDSRPPRLK 4980 >gi|112734870 hypothetical protein LOC57648 [Homo sapiens] Length = 1094 Score = 142 bits (359), Expect = 1e-33 Identities = 195/733 (26%), Positives = 277/733 (37%), Gaps = 97/733 (13%) Query: 34 RPPPPVTPAALRVLGAAGAVG-RKPLAERAGGIGGAT-IPESAPRAGPTRTSRPPASGRG 91 R PP P +L V G G G +PL+ AT + + P A T A GR Sbjct: 313 RAPPLTRPMSLAVPGLTGGAGPAEPLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRC 372 Query: 92 ERAPPAK----NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147 ++ + SP V S GR S + P P + S+ +T + ++++ + + Sbjct: 373 SLRTLSRCSLHSASPASVRSLGRFSSVSSPQPRSRHPS--SSSDTWSHSQSSD----TIV 426 Query: 148 SAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHS 207 S G+ + G + G P + A S + G R +PS S+ S+ + S Sbjct: 427 SDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTL-SIRSSGQLS 485 Query: 208 TTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKG 267 S +RP P R+ S L+ P GP G P P QP Sbjct: 486 GRSVSLRKLKRPPP------PPRRTHSLHQRGLAVP--DGPL--GLPPKPERKQQP---- 531 Query: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQAT 327 Q RPP T + A A P +P + P P S P P +P S + Sbjct: 532 -QLPRPP--TTGGSEGAGA-APCPPNPANSWVPGLSPGGSRRPPRS--PERTLSPSSGYS 585 Query: 328 TSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ 387 + G+PTL L PP SP PP+ +L ++P + +S S ++ S Sbjct: 586 SQSGTPTLPPKG--LAGPPASPGKAQPPKPERVTSL---RSPGASVSSSLTSLCSSSSDP 640 Query: 388 APNALAVHLLQAP----FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443 AP+ + + P F PP P V APFSPP S P SP+ P+ A P++ P+ Sbjct: 641 APSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTT 700 Query: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503 + P SPP + P Q P ++ PPP PP+ PP PP P Sbjct: 701 DASPQSPPTPQTTLTPLQESPVISKD----QSPPPSPPPSYHPPP------PPTKKPEVV 750 Query: 504 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563 +PSA S A P Q P PP PP +P Q P P+ + Sbjct: 751 VEAPSA----SETAEEPLQDP--------NWPPPPPPAPEEQDLSMADFPPPEEAF---- 794 Query: 564 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 623 ++A P PS SP +S P A SSSAT+ + G + PPP Sbjct: 795 --FSVASPEPAGPSGSP-ELVSSP--AASSSSATALQIQPPG---------SPDPPP--- 837 Query: 624 LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 P P APG P G + G E G TP+ + Sbjct: 838 -----------APPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQM 886 Query: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQARLGEL-PLGALQASVVQHLLSRTLLLAAAEG 742 S G GG G A + ++A G P+ A + + + + LAA+EG Sbjct: 887 VRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEG 946 Query: 743 AAGGSGGGPGGAE 755 + GP AE Sbjct: 947 LSSAQPNGPPEAE 959 Score = 106 bits (264), Expect = 1e-22 Identities = 165/615 (26%), Positives = 218/615 (35%), Gaps = 105/615 (17%) Query: 13 AARTPAARAPGLLTPRPPGS---PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGAT 69 A+ T + R+ G L+ R RPPPP P L G LA G +G Sbjct: 472 ASDTLSIRSSGQLSGRSVSLRKLKRPPPP--PRRTHSLHQRG------LAVPDGPLG--- 520 Query: 70 IPESAPRAGPTRTSRPPASGRGERA-----PPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124 +P R + RPP +G E A PP S P SPG G+ RP ++ Sbjct: 521 LPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPG---GSRRPPRSPERT 577 Query: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 182 L S+ + G T PK A G P P + RS A L Sbjct: 578 LSPSSGYSSQSGTPTLPPKGLA---GPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLC 634 Query: 183 -----PAPSARPRPPTEGPRKSVSSASEHSTT----EPSPAARRRPSAGGGLQRPASRSL 233 PAPS R P P H P P+ R P+ PA+ +L Sbjct: 635 SSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPN-------PAAPAL 687 Query: 234 SSSAT---PLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 290 ++ A P+S+ S P + TP+ P Q P + PP PP P P Sbjct: 688 AAPAVVPGPVSTTDAS-PQSPPTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPP--PT 744 Query: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS--PTLQATHSFLPSPPLS 348 + +PSA + P P PP P + S+ P +A S P Sbjct: 745 KKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAG 804 Query: 349 PLATPPPQAPPALALPPLQA----PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS-- 402 P +P + PA + A PP P PP P P+ AP +A + P Sbjct: 805 PSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCS 864 Query: 403 ---PPPSPPVQAPFSPPASPPV-------SPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452 PP V AP P+ + +P P PS PL+ S ASP Sbjct: 865 KGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVP 924 Query: 453 SPS----ATPPPQAPPPLAAPPLQLAKP--PPQAPPALATPPLQALPSPPASF------- 499 +PS A +A A+ L A+P PP+A P PP P+ ASF Sbjct: 925 APSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPR---PPQS--PASTASFIFSKGSR 979 Query: 500 --PGQAPFSPSASLPM---------SPLATPPPQAP--------PVLAAPLLQVPP-SPP 539 + P SP + S PPQAP PV P + VPP + P Sbjct: 980 KLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP 1039 Query: 540 ASPTLQAPRRPPTPG 554 + P + PPT G Sbjct: 1040 SYPRAEPLTAPPTNG 1054 Score = 92.8 bits (229), Expect = 1e-18 Identities = 128/513 (24%), Positives = 172/513 (33%), Gaps = 110/513 (21%) Query: 16 TPAARAPGLL-TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA 74 TP GL P PG +PP P +LR GA+ + L + P + Sbjct: 590 TPTLPPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSD------PAPS 643 Query: 75 PRAGPT-------RTSRPPASGRGE--RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGL 125 R+GP R PP PP+K SP P ++P A+ PGP+ Sbjct: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNP-AAPALAAPAVVPGPVS---- 698 Query: 126 RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185 T+A +S PTP T + + + P P P Sbjct: 699 ------------TTDASPQSP-----------PTPQTTLTPLQESPVISKDQSPPPSPPP 735 Query: 186 SARPRPP-TEGPRKSVSSASEHSTTE-----------PSPAARRRPSAGGGLQRPASRSL 233 S P PP T+ P V + S T E P PA + + P Sbjct: 736 SYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFF 795 Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S ++SP +GPS G+P + P+ P +P A PA P SS+ Sbjct: 796 S-----VASPEPAGPS--GSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSA 848 Query: 294 P-----LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT---SLGSPTLQATHSFLPSP 345 P L P PP + + +P TP S+G+P T + PS Sbjct: 849 PGHVAKLPQKEPVGCSKGGGPPR-EDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSA 907 Query: 346 PLSPL-------ATPPPQ-----------------APPALALPPLQAPPSPPASPPLSPL 381 P PL A+P P A L+ PP PP SP Sbjct: 908 PQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPA 967 Query: 382 ATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF----------SPPASPPVSPSATPPSQA 431 +T S L+ P SP +Q PP +P SP A PP Sbjct: 968 STASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVAR 1027 Query: 432 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464 PS+ P PP+ P+ P P PP P Sbjct: 1028 KPSVGVP----PPASPSYPRAEPLTAPPTNGLP 1056 >gi|47132519 Ras association and pleckstrin homology domains 1 isoform 1 [Homo sapiens] Length = 1250 Score = 142 bits (358), Expect = 1e-33 Identities = 175/645 (27%), Positives = 234/645 (36%), Gaps = 83/645 (12%) Query: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA-EETVARGKATEAPKRSA 146 SG + P ++ S G S T G + + + S E RG E ++ Sbjct: 536 SGSSSSSIPESQSNHSNQSDSG-VSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKAR 594 Query: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS-VSSASE 205 + + R TS P +P P + A+ LP P P P PP P + S S Sbjct: 595 MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSA 654 Query: 206 HSTTEPSPA---------ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 S +P + G L +P + + S + P P P Sbjct: 655 PSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV--KPQILVPPNGVVPPP 712 Query: 257 PAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315 P P P P A L+P P + PL + + APP+P PP + Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPA- 771 Query: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375 P PP PP T + +PT +T + P + TP P PPA P A PP S Sbjct: 772 PLPPQAPPKPLVT-IPAPT--STKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP-S 827 Query: 376 PPLSPLATPSPQAP--NALAVHLLQAPFSPPPS--PPVQAPFSPPASPPVSPS------- 424 PP P+ P P P + +P SP PS + + F PP +PP S Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887 Query: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA----PPPLAAPPLQLAKPPPQA 480 A Q+PP++ A P P S P P P PPP++ PPP PP + PPP Sbjct: 888 ANVAPQSPPAVKAKPKWQPSSIPVPSPDFP--PPPPESSLVFPPP---PPSPVPAPPPPP 942 Query: 481 PP-ALATPPLQALP--------SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531 PP A TP P SP P P S+ S P P+ P V + Sbjct: 943 PPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVS 1002 Query: 532 LQVPPSPPASP---TLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588 PP+ SP TL P PP PG ++SG L L G + P Sbjct: 1003 KFTPPAESGSPSKETLPPPAAPPKPG-KLNLSGVNLPGVLQQG---------CVSAKAPV 1052 Query: 589 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH---PAAWSRGPAPPLAFRGA 645 L+G + + + S P PPP+ EL PA +S +P +A Sbjct: 1053 LSGRGK------DSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAV--V 1104 Query: 646 PGAPLPW--------PPATGPGSADG--LCTIYETEGPESATPAP 680 P W PP T P D L +E P AT P Sbjct: 1105 NPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVP 1149 Score = 120 bits (302), Expect = 4e-27 Identities = 137/501 (27%), Positives = 170/501 (33%), Gaps = 91/501 (18%) Query: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ-------VTPPRKDAAPALGPLSSS 293 SS +SG S+ P + ++ S G+ +P V+ +A L S Sbjct: 531 SSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP 353 A P S P L P P P A+ PSPPL P P Sbjct: 591 SKARMESMNRPYTSLVPPLS--PQPKIVTPYTASQ--------------PSPPLPP---P 631 Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413 PP PP PP PP PP PPL + PS + + V S A F Sbjct: 632 PPPPPP----PP---PPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF 684 Query: 414 SPPASPPV--SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP--PPLAAP 469 PP +PPV S S P PP+ PP PP PP P P AP P +AP Sbjct: 685 KPP-TPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP 743 Query: 470 P-----------LQLAKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLA 517 P Q+A P P PP + P P QA P P + P AP S P+ A Sbjct: 744 PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP--APTSTKTVAPVVTQA 801 Query: 518 TPPPQAPPVLAAPLLQVPPSP--PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 PP PPV PP+ PA P P PPTP P P PP Sbjct: 802 APPTPTPPV--------PPAKKQPAFPASYIPPSPPTP----------------PVPVPP 837 Query: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635 P+ + S S +++ P PP E P + Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPP------TPPAMESQPLKPVPANVA 891 Query: 636 PAPPLAFRGAP-----GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPG 690 P P A + P P+P P P L P A P P P+P Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPD 951 Query: 691 TSG--GKAAAGAGAGASSRSP 709 SG GK + + + P Sbjct: 952 KSGSPGKKTSKTSSPGGKKPP 972 Score = 120 bits (300), Expect = 7e-27 Identities = 164/671 (24%), Positives = 230/671 (34%), Gaps = 113/671 (16%) Query: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK-------PLAERAGGIG 66 A P+ P P PP P PPPP P + +AG+ + A Sbjct: 621 ASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHS 680 Query: 67 GATIPESAPRAGPTRTSRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQ 122 GA P +++ +P P +G PP P P +PG A +P P Sbjct: 681 GALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPP-----PPPPPTPGSAMAQLKPAPCAP 735 Query: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR 182 + SA P + PTP P P A A + + Sbjct: 736 SLPQFSA----------PPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTI 785 Query: 183 PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSS 242 PAP++ T+ V+ A+ + T P P A+++P+ P+ + P + Sbjct: 786 PAPTS-----TKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTL 840 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302 P + A+ P +P P K + + PP TPP ++ P L P+ ++ P+ Sbjct: 841 PKQQSFCAK-PPPSPLSPVPSVVKQIASQFPPPPTPPAMESQP-LKPVPANVAPQSPPAV 898 Query: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP-AL 361 P PS +PSP PP ++ + P PP SP+ PPP PP A Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLV-----------FPPPPPSPVPAPPPPPPPTAS 947 Query: 362 ALPPLQAPPSPPASPPLSPLATPSPQAP--NALAVHLLQAPFSPPPSPPVQ---APFSPP 416 P P S SP P P N+ A P P V + F+PP Sbjct: 948 PTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007 Query: 417 A-SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPP------PQAPPPLAAP 469 A S S PP APP L P SA P + +P Sbjct: 1008 AESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP 1067 Query: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASL---------PMSPLATPP 520 P PPP L PP++ PA F G SP ++ MS PP Sbjct: 1068 PSDSDFPPPPPETELPLPPIEI----PAVFSGNT--SPKVAVVNPQPQQWSKMSVKKAPP 1121 Query: 521 PQAP----------------PVLAAPLLQVPPSPPASPTLQ--------------APRRP 550 P P P +A + QVP SP +S ++Q + R Sbjct: 1122 PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRH 1181 Query: 551 PTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGP 610 + S + P T+ PPPPP LS AG+ S + GY + Sbjct: 1182 GSLSSRMSRAEPTATMDDMALPPPPP-----ELLSDQQKAGYGGS------HISGYATLR 1230 Query: 611 EGGAAASPPPD 621 G A P D Sbjct: 1231 RGPPPAPPKRD 1241 >gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo sapiens] Length = 1560 Score = 140 bits (353), Expect = 5e-33 Identities = 187/716 (26%), Positives = 259/716 (36%), Gaps = 126/716 (17%) Query: 15 RTPAARAPGLLTPRPPGSPRPPPPV----------------TPAALRVL--GAAGAVGRK 56 + P A G P+PPG+ P V P + L GA + Sbjct: 425 KQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQ 484 Query: 57 PLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 116 L+ +GG + +AP G + P + + P S GPV +P Sbjct: 485 QLSALPANVGGQILAAAAPHTGGQLIANPILTNQNLAGP----LSLGPVLAPHS------ 534 Query: 117 PGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGT 176 G I + + G+ +L+AG+ S P P P+ + Sbjct: 535 ----GAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPP 590 Query: 177 EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--GGGLQRPASRSLS 234 P +P T P + A+ T +P+P A S GLQ+P ++ Sbjct: 591 SAVAMLNTPDGLVQPAT--PAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPP 648 Query: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP---RKDAAPALGPLS 291 + TP + + P TP+ P+ P+ + +PP TP +D+ P Sbjct: 649 QAPTPQA----AAPPQATTPQ-PSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQE 703 Query: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA 351 S P + P S P S+ PPA P+ AT P + +P Sbjct: 704 RS--QQPLSAEGPHLSVPASVIVSAPPPAQDPAPAT-----PVAKGAGLGPQAPDSQASP 756 Query: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411 P PQ P A PL+ P P+S P P P +P+ + H + P PP P Q+ Sbjct: 757 APAPQIP---AAAPLKGP--GPSSSPSLPHQAPLGDSPHLPSPHPTRPPSRPPSRP--QS 809 Query: 412 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471 PP+ PP+ P PP QAPP+L P + V + PP P++ P P AP P PPL Sbjct: 810 VSRPPSEPPLHP--CPPPQAPPTL--PGIFVIQNQLGVPP--PASNPAPTAPGP-PQPPL 862 Query: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531 + PP+ PL P P S A S S + P TP Sbjct: 863 RPQSQPPEG-------PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQ-------- 907 Query: 532 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP---GPPPPPSRS--------- 579 LQ PPS Q P + PTP P TL L P PPPPP R+ Sbjct: 908 LQFPPS-------QGPHKSPTPPP---------TLHLVPEPAAPPPPPPRTFQMVTTPFP 951 Query: 580 ----PSSTL-------SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 P + L SG L + A + P+ GP AAS + + Sbjct: 952 ALPQPKALLERFHQVPSGIILQNKAGGAPAAPQ--TSTSLGPLTSPAASVLVSGQAPSGT 1009 Query: 629 PAAWSRGPAP-PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 P A S PAP P+A G P P PA A L T+ + S P L Sbjct: 1010 PTAPSHAPAPAPMAATGLP----PLLPAENKAFASNLPTLNVAKAASSGPGKPSGL 1061 Score = 139 bits (349), Expect = 1e-32 Identities = 215/805 (26%), Positives = 301/805 (37%), Gaps = 162/805 (20%) Query: 20 RAPGLLTPRPPGSPRP------PPPVTPAA--LRVLGAAGAVGRKPLAER-----AGGIG 66 R P + P+P G P P P PA L + G GA+ ++P A + A G Sbjct: 346 RTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQGEPGALPQQPKAPQNLTFMAAGKA 405 Query: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126 G + S A P + PPA T P PG S L Q Sbjct: 406 GQNVVLSGFPA-------PALQANVFKQPPATTTGAAPPQPPGALSKPMSVHLLNQGSSI 458 Query: 127 ISAEETVARGK---------ATEAPKR-SALSA---GARRDTSGPTPG---TPSPAMARR 170 + + + G+ A + P++ SAL A G + P G +P + + Sbjct: 459 VIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGGQILAAAAPHTGGQLIANPILTNQ 518 Query: 171 SRAAGTEVGLPRPAP----------SARP----RPPTEGPRKSVSSASEHSTTEPSPAAR 216 + A +G P AP SA P +P S+++ S + ++P+PA Sbjct: 519 NLAGPLSLG-PVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGP 577 Query: 217 RRPSAGGGLQRPASR--------SLSSSATPLSSPARSGP--SARGTPRAPAHPSQPKPK 266 + G+ P S L ATP ++ + P + + P+AP S P P Sbjct: 578 AATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPL 637 Query: 267 GLQ---ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPP 323 GLQ A +PPQ P+ A P TP PS P ++ P L PP+ P Sbjct: 638 GLQQPQAQQPPQAPTPQAAAPPQA--------TTPQPS--PGLASSPEKIVLGQPPSATP 687 Query: 324 SQATTSLGSPTLQATHSFLPSP----PLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 379 + T + FLP PLS A P + PA + + APP P + Sbjct: 688 TAILTQ------DSLQMFLPQERSQQPLS--AEGPHLSVPASVI--VSAPPPAQDPAPAT 737 Query: 380 PLATPS---PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436 P+A + PQAP++ QA +P P P AP P P SPS P QAP Sbjct: 738 PVAKGAGLGPQAPDS------QASPAPAPQIPAAAPLKGPG-PSSSPSL--PHQAP---- 784 Query: 437 APPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496 L P P SP T PP PP + P +++PP + PPL P P Sbjct: 785 ---LGDSPHLP-----SPHPTRPPSRPP---SRPQSVSRPPSE-------PPLHPCPPPQ 826 Query: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556 A P P + + L PPP + P AP PP PP P Q P P Sbjct: 827 A-----PPTLPGIFVIQNQLGVPPPASNP---APTAPGPPQPPLRPQSQPPEGP------ 872 Query: 557 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS-GPEGGAA 615 L P P PPS + S+ S + + + T + +L+ S GP + Sbjct: 873 -----------LPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDFQLQFPPSQGPH--KS 919 Query: 616 ASPPPDAELAACHPAAWSRGPAPPLAFR--GAPGAPLPWPPA---TGPGSADGLCTIYET 670 +PPP L P + P PP F+ P LP P A G+ + Sbjct: 920 PTPPPTLHLV---PEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKA 976 Query: 671 EGPESATPAPGALDPGPSPGTS---GGKAAAGAGAGASSRSPKQARLGELPLGALQASVV 727 G +A +L P SP S G+A +G A S +P A + L L + Sbjct: 977 GGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPT-APSHAPAPAPMAATGLPPLLPAEN 1035 Query: 728 QHLLSRTLLLAAAEGAAGGSGGGPG 752 + S L A+ A+ G G G Sbjct: 1036 KAFASNLPTLNVAKAASSGPGKPSG 1060 Score = 85.1 bits (209), Expect = 2e-16 Identities = 195/799 (24%), Positives = 262/799 (32%), Gaps = 117/799 (14%) Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77 +A P L P PPP PA + +G + +A IP +AP Sbjct: 710 SAEGPHLSVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLK 769 Query: 78 GPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137 GP +S P + SP P P +RP Q R +E + Sbjct: 770 GPGPSSSPSLPHQAPLGDSPHLPSPHPTRPP------SRPPSRPQSVSRPPSEPPLHPCP 823 Query: 138 ATEAPK--------RSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSAR 188 +AP ++ L PT PG P P + +S+ P P A Sbjct: 824 PPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPGPPQPPLRPQSQPP------EGPLPPA- 876 Query: 189 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGP 248 P P +V+S+SE S+ P+P + LQ P S+ S TP P Sbjct: 877 PHLPPSSTSSAVASSSETSSRLPAPT-----PSDFQLQFPPSQGPHKSPTP-------PP 924 Query: 249 SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA--------------------APALG 288 + P PA P P P+ Q + P P+ A APA Sbjct: 925 TLHLVPE-PAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAP 983 Query: 289 PLSSS--PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH----SFL 342 S+S PL +P+ S S AP T PS P A T L P L A + S L Sbjct: 984 QTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMAATGL-PPLLPAENKAFASNL 1042 Query: 343 PSPPLSPLATPPPQAPPAL----ALPPLQAPPSPPASPP--------------LSP-LAT 383 P+ ++ A+ P P L L L+ PP+ S L P T Sbjct: 1043 PTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSKEACFLEHLHKHQGSVLHPDYKT 1102 Query: 384 PSPQAPNA----LAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAP 438 P +A L H+ Q SP V F ++ + + ++ L Sbjct: 1103 AFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEEFETVSTQLLKRTQAMLNKYRLLLLEE 1162 Query: 439 PLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP----QAPPALATPPLQALPS 494 +V P S M Q A QLAK P + +L P A S Sbjct: 1163 SRRVSP----SAEMVMIDRMFIQEEKTTLALDKQLAKEKPDEYVSSSRSLGLP--IAASS 1216 Query: 495 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 554 PG P S SA P A+ P PP L L+ SP++ R + Sbjct: 1217 EGHRLPGHGPLSSSA-----PGASTQP--PPHLPTKLVIRHGGAGGSPSVTWARASSSLS 1269 Query: 555 PDTSVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 613 +S S +L A GP P +R P T G + + Sbjct: 1270 SSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDP 1329 Query: 614 AAASPPPDAELAACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEG 672 PPP A L P P PP G P P P P C Sbjct: 1330 VHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHC----PRL 1385 Query: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQ--ASVVQHL 730 P T PG GT G+A G S +P A++ E G ++ A+V L Sbjct: 1386 PLRKTYRENVGGPGAPEGTPAGRARGG------SPAPLPAKVDEATSGLIRELAAVEDEL 1439 Query: 731 LSRTLLLAAAEGAAGGSGG 749 R L E AA + G Sbjct: 1440 YQRMLKGPPPEPAASAAQG 1458 Score = 77.8 bits (190), Expect = 4e-14 Identities = 100/358 (27%), Positives = 131/358 (36%), Gaps = 56/358 (15%) Query: 13 AARTPAARAPGLLTPRPPGSPRP-PPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA--- 68 A TP A+ GL P P P P PAA + G + P +G + Sbjct: 734 APATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPS--SSPSLPHQAPLGDSPHL 791 Query: 69 -----TIPESAPRAGPTRTSRPPASGRGERAPP--AKNTSPG--------PVSSPGRASG 113 T P S P + P SRPP+ PP A T PG V P Sbjct: 792 PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPA 851 Query: 114 TTRPGPLGQKGLRISAEETVARGKATEAP------KRSALSAGARRDTSGPTPGTPSPAM 167 T PGP Q LR ++ G AP SA+++ + + P P TPS Sbjct: 852 PTAPGP-PQPPLRPQSQP--PEGPLPPAPHLPPSSTSSAVASSSETSSRLPAP-TPSDFQ 907 Query: 168 ARRSRAAGTEVGLPRPAPS----ARPRPPTEGPRKSVSSASEHSTTEPSPAA-----RRR 218 + + G P P P+ P P P ++ + P P A + Sbjct: 908 LQFPPSQGPHKS-PTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQV 966 Query: 219 PS-------AGGGLQRPASRSLSSSATPLSSPAR----SGPSARGTPRAPAHPSQPKPKG 267 PS AGG PA+ S+S PL+SPA SG + GTP AP+H P P Sbjct: 967 PSGIILQNKAGGA---PAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHAPAPAPMA 1023 Query: 268 LQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325 L PP + K A L L+ + A+ P P L L PP PS+ Sbjct: 1024 ATGL-PPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTLQPSK 1080 Score = 67.8 bits (164), Expect = 4e-11 Identities = 162/725 (22%), Positives = 228/725 (31%), Gaps = 110/725 (15%) Query: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73 A PA APG P+PP P+ PP P P + + + ++ S Sbjct: 847 ASNPAPTAPG--PPQPPLRPQSQPPEGPLP--------PAPHLPPSSTSSAVASSSETSS 896 Query: 74 ---APRAGPTRTSRPPASG--RGERAPPAKNTSPGPVSSPGRASGT----TRPGP-LGQK 123 AP + PP+ G + PP + P P + P T T P P L Q Sbjct: 897 RLPAPTPSDFQLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQMVTTPFPALPQP 956 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG---L 180 + V G + A +A + GP + + +GT Sbjct: 957 KALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAASVLVSGQAPSGTPTAPSHA 1016 Query: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP---------SAGGGLQRPASR 231 P PAP A P P ++ + AS T + AA P S GL++P + Sbjct: 1017 PAPAPMAATGLPPLLPAENKAFASNLPTLNVAKAASSGPGKPSGLQYESKLSGLKKPPTL 1076 Query: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPS-----------------QPKPKGLQALRPP 274 S A L + S A PS P P + Sbjct: 1077 QPSKEACFLEHLHKHQGSVLHPDYKTAFPSFEDALHRLLPYHVYQGALPSPSDYHKVDEE 1136 Query: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL----------------QTLPSP 318 T + L+ L S SPSA + + L Sbjct: 1137 FETVSTQLLKRTQAMLNKYRLLLLEESRRVSPSAEMVMIDRMFIQEEKTTLALDKQLAKE 1196 Query: 319 PATPPSQATTSLGSPTLQAT--HSFLPSPPLSPLAT-----PPPQAPPALALPPLQAPPS 371 ++ SLG P ++ H PLS A PPP P L + A S Sbjct: 1197 KPDEYVSSSRSLGLPIAASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGS 1256 Query: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS---PPVQA--PFSPPASPPVSPSAT 426 P + + + S + ++ A L P PS PP++ S Sbjct: 1257 PSVTWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEA 1316 Query: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486 S+ + A P+ PP PPA+ ++ PP PPP + PPP AP Sbjct: 1317 GLSKVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAP---ER 1373 Query: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546 PL P P P + + + P +P TP +A APL P+ T Sbjct: 1374 KPLGTAPHCP-RLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPL----PAKVDEATSGL 1428 Query: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 606 R + + L + GPPP P+ S + PD A P R Sbjct: 1429 IR-------ELAAVEDELYQRMLKGPPPEPAASAAQGTGDPDW-----EAPGLPPAKRRK 1476 Query: 607 DSGPEGGAAA----SPPPDAELAACHPA---------AWSRGPAPPLAFRGAPGAPLPWP 653 P+ A+ SP D A A R PAP + G P P Sbjct: 1477 SESPDVDQASFSSDSPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPP 1536 Query: 654 PATGP 658 P P Sbjct: 1537 PLHRP 1541 Score = 56.6 bits (135), Expect = 9e-08 Identities = 96/364 (26%), Positives = 130/364 (35%), Gaps = 104/364 (28%) Query: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSP-----AARRRPSAGGG--- 224 ++ +GLP A S R P GP +SS++ ++T+P P R AGG Sbjct: 1203 SSSRSLGLPIAASSEGHRLPGHGP---LSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSV 1259 Query: 225 LQRPASRSLSSSATPLSS------------PARSGPSAR--------------------- 251 AS SLSSS++ S+ P+R+ P + Sbjct: 1260 TWARASSSLSSSSSSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLS 1319 Query: 252 ----GTPRAPAHPSQPKPKGLQALRPPQVTPP--------------RKDAAPALGPLSSS 293 T P H P P L+ PP PP AAP PL ++ Sbjct: 1320 KVVHNTALDPVHQPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTA 1379 Query: 294 PLATPSP---------SAPPSPSAPPSLQTLPSPPATPPS---QATT----SLGSPTLQA 337 P P P +P P+ + PA P+ +AT+ L + + Sbjct: 1380 PHCPRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDEL 1439 Query: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA------SPPL--SPLATPSPQAP 389 L PP P A+ A P +AP PPA SP + + ++ SPQ Sbjct: 1440 YQRMLKGPPPEPAAS----AAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQ-D 1494 Query: 390 NALAVH----------LLQAP-FSPPPSPPVQAPFSPPASPPV--SPSATPPSQAPPSLA 436 + L H L QAP +P PS P A PASPP P A PPS L Sbjct: 1495 DTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHNGGLG 1554 Query: 437 APPL 440 A L Sbjct: 1555 ARTL 1558 Score = 53.9 bits (128), Expect = 6e-07 Identities = 132/504 (26%), Positives = 175/504 (34%), Gaps = 68/504 (13%) Query: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--------GLQALRPPQV 276 L+ A L P PA G G A A + P+ GLQ PP V Sbjct: 118 LEAEAELDLGPFQLPTLQPADGGAGPTGAGGAAAVAAGPQALFPGSTDLLGLQG--PPTV 175 Query: 277 ------TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSL 330 PP+ AL S P P + P LQ LP+ +P +L Sbjct: 176 LTHQALVPPQDVVNKAL---SVQPFLQPVGLGNVTLQPIPGLQGLPN--GSPGGATAATL 230 Query: 331 GSPTLQATHSFLPSPPLSPLATPPPQA-PPALALPPLQAPPSPPASPPLSPLATPSPQAP 389 G +Q P+ L TP Q + + A + P+ P A SPQ Sbjct: 231 GLAPIQVV-----GQPVMALNTPTSQLLAKQVPVSGYLASAAGPSEPVTLASAGVSPQGA 285 Query: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 + L A + + + AS +P+ TP Q P AP L P PA Sbjct: 286 GLVIQKNLSAAVATTLNGNSVFGGAGAAS---APTGTPSGQ--PLAVAPGLGSSPLVPA- 339 Query: 450 PPMSPSATPPPQAPPPLAA-PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 P + TP P P P PP P PA AT +Q PG P P Sbjct: 340 PNVILHRTPTPIQPKPAGVLPPKLYQLTPKPFAPAGATLTIQ-------GEPGALPQQPK 392 Query: 509 ASLPMSPLATPPPQAPPVLA---APLLQ--VPPSPPASPTLQAPRRPPTPGPDTSVSGPR 563 A ++ +A VL+ AP LQ V PPA+ T AP +PP ++S P Sbjct: 393 APQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPPATTTGAAPPQPP-----GALSKPM 447 Query: 564 LTLALAPGPP---PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG--AAASP 618 L G P P + A P++L + G AAA+P Sbjct: 448 SVHLLNQGSSIVIPAQHMLPGQN----QFLLPGAPAVQLPQQLSALPANVGGQILAAAAP 503 Query: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678 +L A +P ++ A PL+ G L P +G SA L G + Sbjct: 504 HTGGQLIA-NPILTNQNLAGPLSL----GPVL--APHSGAHSAHILSAAPIQVGQPALFQ 556 Query: 679 APGALDPGPSPGTSGGKAAAGAGA 702 P +L G P T A AG A Sbjct: 557 MPVSLAAGSLP-TQSQPAPAGPAA 579 Score = 48.1 bits (113), Expect = 3e-05 Identities = 88/368 (23%), Positives = 125/368 (33%), Gaps = 67/368 (18%) Query: 13 AARTPAARAPGL--LTPRPPGSPRPPPPVTPAALRVL-GAAGAVGRKPLAERAGGIGGAT 69 AA + R PG L+ PG+ PPP P L + G AG A + + ++ Sbjct: 1213 AASSEGHRLPGHGPLSSSAPGASTQPPPHLPTKLVIRHGGAGGSPSVTWARASSSLSSSS 1272 Query: 70 IPESAPRA------GPTRT-SRPPASGRGERA---------------PPAKNTSPGPVSS 107 SA + GP + +RPP R+ NT+ PV Sbjct: 1273 SSSSAASSLDADEDGPMPSRNRPPIKTYEARSRIGLKLKIKQEAGLSKVVHNTALDPVHQ 1332 Query: 108 PGRASGTTR-----------PGPLGQKGLRI-----SAEETVARGKATEAPKRSALSAGA 151 P T + P P GQ + +A E G A P R L Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCP-RLPLRKTY 1391 Query: 152 RRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP 211 R + GP G P A R+R G P P P A+ T G + +++ + Sbjct: 1392 RENVGGP--GAPEGTPAGRARG-----GSPAPLP-AKVDEATSGLIRELAAVEDELYQRM 1443 Query: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271 L+ P +S+A P P R + + Sbjct: 1444 -------------LKGPPPEPAASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSD 1490 Query: 272 RPPQ--VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA--PPSLQTLPSPPATPPSQAT 327 P +T + A ++ L +P TP+PS P + SA P S L P A PPS Sbjct: 1491 SPQDDTLTEHLQSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPPLHRPEAYPPSSHN 1550 Query: 328 TSLGSPTL 335 LG+ TL Sbjct: 1551 GGLGARTL 1558 >gi|112421108 capicua homolog [Homo sapiens] Length = 1608 Score = 139 bits (349), Expect = 1e-32 Identities = 203/828 (24%), Positives = 277/828 (33%), Gaps = 152/828 (18%) Query: 25 LTPRPPGSPRPPPPVTP--AALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR- 81 L P PPG P PP + A+ A + +G T G T Sbjct: 510 LDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAG 569 Query: 82 TSRPPASGRGERAPPAKNTSPGPV-------SSPGRASGTTRPGPLGQKGLRISAEETVA 134 RPP G G A P+K T P+ P G PGP + A Sbjct: 570 PLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAPPSG 623 Query: 135 RGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP---RP 183 G + P + G R S P P G P+ ++R + T V P P Sbjct: 624 GGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTP 683 Query: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 P A PT G ++ + + + TE +R + G+ S S++AT + Sbjct: 684 VPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPH 743 Query: 244 ARSGPSARGTPRAPAHPSQ----------PKPKGLQAL---RPPQVTPPRKDAAPALGPL 290 +GP +APA + P P +Q + P T A GP Sbjct: 744 LVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPN 803 Query: 291 SSSPLATPSPSAPPS-----------PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 339 PL P A P+ P LQ P+P P ++A G + Sbjct: 804 GPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIR 863 Query: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLL 397 LP P S P +P LQ+ PS PP + +SP+ P P L + Sbjct: 864 FTLP-PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKV 922 Query: 398 QAPFSPP-----------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446 P + P P P V SPP S PV A PPS+ + P+ V Sbjct: 923 LVPLAAPSMSVRGGGAGQPLPLV----SPPFSVPVQNGAQPPSKI---IQLTPVPVSTPS 975 Query: 447 PASPPMSPSATPPPQAPPPLA-----------------APPLQLAKPPPQAPPALATPPL 489 PP+SP+ P P + P A PL + QA + P Sbjct: 976 GLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPT 1035 Query: 490 QAL--------PSPPASF-----PGQAPFSPSASLPMSPLATPPPQAPPVLAA---PLLQ 533 ++ PS PA GQAP + +SP+ P PQ PP AA P++ Sbjct: 1036 SSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPV--PSPQLPPACAAPGGPVIT 1093 Query: 534 VPPSPPASPTLQAPRRPPTPGPD-------TSVSGPRLTLALAPGPPPPPSRSPSSTLSG 586 S +PT AP P+ P TS + P T+ L GPP P + +P+ T Sbjct: 1094 AFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATI-LPKGPPAPATATPAPTSPF 1152 Query: 587 PD-LAGHSSSATSTPEELRGYDSGP---------------EGGAAASPPPDAELAACHPA 630 P AG + + P+ R P E GA+ P P A P Sbjct: 1153 PSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP-APRQPLEPG 1211 Query: 631 AWSRGPAPPLAFRGAPGAPLP------W-----------PPATGPGSADG---LCTIYET 670 AP G P P P W PPA SA G + + + + Sbjct: 1212 PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPS 1271 Query: 671 EGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718 + P G + G P A G SS S G+ P Sbjct: 1272 SSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAAGDTP 1319 Score = 138 bits (347), Expect = 2e-32 Identities = 212/773 (27%), Positives = 272/773 (35%), Gaps = 152/773 (19%) Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATI 70 G AR P+A AP L P P PAA V V P+ I Sbjct: 642 GGGARVPSAPAPSLAYGAPAA-----PLSRPAATMVTNVVRPVSSTPVP-----IASKPF 691 Query: 71 PESA-PRAGPTRTSRPPAS-GRGERAP---------------PAKNTSPGPVSSPGRASG 113 P S A P T+ G G R P A TSP P G G Sbjct: 692 PTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLG 751 Query: 114 TTRPGPLGQKGLRIS----------AEETVARGKATEAPKRSALSAGARRDTSGPTP-GT 162 T P L + A + +A+G A + AGA +GP P G Sbjct: 752 TVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQG-APGGGTTAGSGAGAGSGPNGPVPLGI 810 Query: 163 PSP-AMARRSRAAGTEVGLP------RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 215 P A+ + + LP + AP+ P P T+ S P+P Sbjct: 811 LQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPS----------GPAPTT 860 Query: 216 RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 275 R + G +++ TP G P + PS P PK Q++ P Q Sbjct: 861 SIRFTLPPGTSTNGKVLAATAPTP------------GIPILQSVPSAPPPKA-QSVSPVQ 907 Query: 276 VTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTL 335 PP A G + PLA PS S + P L SPP + P Q S + Sbjct: 908 APPPGGSAQLLPGKVLV-PLAAPSMSVRGGGAGQPL--PLVSPPFSVPVQNGAQPPSKII 964 Query: 336 QATHSFLPSP-----PLSPLATPPPQAPPALALPPLQ------------APP--SPPASP 376 Q T + +P PLSP P P + P L P A P + PAS Sbjct: 965 QLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASS 1024 Query: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV----QAPFSPPASPPVSPSATPPSQAP 432 + + P + AL L P P P+ QAP P VSP +P Q P Sbjct: 1025 QAGTVTSYGPTSSVALGFTSL-GPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP--QLP 1081 Query: 433 PSLAAPPLQV-------PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-----PQA 480 P+ AAP V P+P +S P++ P QAPP L PP P+ Sbjct: 1082 PACAAPGGPVITAFYSGSPAPTSSAPLAQ----PSQAPPSLVYTVATSTTPPAATILPKG 1137 Query: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP----P 536 PPA AT A P+P + FP S + SL P P+AP + A + +P Sbjct: 1138 PPAPAT----ATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFE 1193 Query: 537 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA 596 + + APR+P PGP + P L P PP PP + T + SS Sbjct: 1194 AGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPT-----ARSSPP 1248 Query: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 P E R GPE A+ P ++ W R P L RG P P P PA Sbjct: 1249 LPPPAEERTSAKGPETMASKFPSSSSD--------W-RVPGQGLENRGEP--PTPPSPAP 1297 Query: 657 GPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709 P A G G ++ A D T K AAG G R P Sbjct: 1298 APAVAPG--------GSSESSSGRAAGD------TPERKEAAGTGKKVKVRPP 1336 Score = 127 bits (319), Expect = 4e-29 Identities = 177/732 (24%), Positives = 252/732 (34%), Gaps = 98/732 (13%) Query: 28 RPPGSPRPPPPVTPAALRVLG--------AAGAVGRKPLAERAGGIGGATIPESAPRAGP 79 RPP P PP P P G A+ A + +G T G Sbjct: 507 RPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGS 566 Query: 80 TRTS-RPPASGRGERAPPAKNTSPGPVSS-------PGRASGTTRPGPLGQKGLRISAEE 131 T RPP G G A P+K T P+ P G PGP + A Sbjct: 567 TAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGP------SVIAAP 620 Query: 132 TVARGKATEA----PKRSALSAGARRDTSGPTP----GTPSPAMARRSRAAGTEVGLP-- 181 G + P + G R S P P G P+ ++R + T V P Sbjct: 621 PSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVS 680 Query: 182 -RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 P P A PT G ++ + + + TE +R + G+ S S++AT Sbjct: 681 STPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP 740 Query: 241 SSPARSGPSARGTPRAPAHPSQ----------PKPKGLQALR---PPQVTPPRKDAAPAL 287 + +GP +APA + P P +Q + P T A Sbjct: 741 APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGS 800 Query: 288 GPLSSSPLATPSPSAPPS-----------PSAPPSLQTLPSPPATPPSQATTSLGSPTLQ 336 GP PL P A P+ P LQ P+P P ++A G Sbjct: 801 GPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTT 860 Query: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAV 394 + LP P S P +P LQ+ PS PP + +SP+ P P L Sbjct: 861 SIRFTLP-PGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLP 919 Query: 395 HLLQAPFSPP-----------PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP 443 + P + P P P V SPP S PV A PPS+ + P+ V Sbjct: 920 GKVLVPLAAPSMSVRGGGAGQPLPLV----SPPFSVPVQNGAQPPSKI---IQLTPVPVS 972 Query: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQA 503 PP+SP+ P P + P P Q+ A P L + PAS Sbjct: 973 TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALP----LGTSPASSQAGT 1028 Query: 504 --PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG--PDTSV 559 + P++S+ + + P + P PLL +P +P P+P P + Sbjct: 1029 VTSYGPTSSVALGFTSLGP--SGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAA 1086 Query: 560 SGPRLTLALAPGPPPPPSRSPSSTLS-GPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618 G + A G P P S +P + S P ++ + ++TP GP A A+P Sbjct: 1087 PGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATP 1146 Query: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 678 P + + + + P A R +P AP A + E S P Sbjct: 1147 APTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS------IPVGSFEAGASGRP 1200 Query: 679 APG---ALDPGP 687 P L+PGP Sbjct: 1201 GPAPRQPLEPGP 1212 Score = 97.4 bits (241), Expect = 5e-20 Identities = 139/555 (25%), Positives = 198/555 (35%), Gaps = 55/555 (9%) Query: 8 AKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG 67 A A A + A APG T G+ P P L +L GA+G+ AGGI Sbjct: 772 APAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGIL-QPGALGK------AGGITQ 824 Query: 68 AT-IPESAPRAGPTRTSRPPASGRGERAP--PAKNTS-----PGPVSSPGRASGTTRPGP 119 I + P+ + PA G AP PA TS P S+ G+ T P P Sbjct: 825 VQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPTP 884 Query: 120 LGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT-----PSPAMARRSRAA 174 I ++V +A S + A ++ PG +P+M+ R A Sbjct: 885 ------GIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGA 938 Query: 175 GTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234 G + L P S + + P K + +T P+ G + L Sbjct: 939 GQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLL 998 Query: 235 SSATPLSSPARSGPSARGTPRAPAH----------PSQPKPKGLQALRP--PQVTPPRKD 282 S+T ++ +G A +PA P+ G +L P P P Sbjct: 999 PSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLS 1058 Query: 283 A--APALGPLSSSPLATPSPSAPPSPSAP--PSLQTLPSPPATPPSQATTSLGS---PTL 335 A AP L P PSP PP+ +AP P + S P S A + S P+L Sbjct: 1059 AGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSL 1118 Query: 336 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 395 T + +PP + + P AP P PS A L P Q P+ A Sbjct: 1119 VYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQ 1178 Query: 396 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 455 ++A + P +A S P P P+ L+ P+PPA PP+ + Sbjct: 1179 KVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPET 1238 Query: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 515 TP ++ PPL PP + + P A P +S + P + P Sbjct: 1239 WTPTARSSPPL--------PPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPP 1290 Query: 516 LATPPPQAPPVLAAP 530 TPP AP AP Sbjct: 1291 --TPPSPAPAPAVAP 1303 Score = 91.3 bits (225), Expect = 3e-18 Identities = 193/821 (23%), Positives = 278/821 (33%), Gaps = 191/821 (23%) Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRS 145 PAS G + P + +PGP ++PG G R S + A T +R Sbjct: 383 PASYSGPK-PSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDEERM 441 Query: 146 AL----------------------------SAGARRDTSGPTP----GTPSPAMARRSRA 173 + + D+SG P G + R+ Sbjct: 442 VICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGNKGFGRKVFSPVIRS 501 Query: 174 AGTEVGLP-RPAPSARPRPPTEGPR--KSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230 + T P P P P PP + S S+S S S +A S G G + Sbjct: 502 SFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQE 561 Query: 231 RSLSSSATPL-------SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPP--------- 274 S+A PL PA + R P PA + +P+ + L PP Sbjct: 562 SGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPP 621 Query: 275 ---------QVTPPRKDAAPALGP-LSSSPLATPSPSAPPSPSAPPS----------LQT 314 V PP K+ G + S+P + + AP +P + P+ + + Sbjct: 622 SGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSS 681 Query: 315 LPSPPATPP--------SQATTSLGSPTLQATHSFLP-----------SPPLSPLATPPP 355 P P A+ P + + G+ T T S +P S S AT P Sbjct: 682 TPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSP- 740 Query: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-------------APFS 402 AP +A P L PA+ + TP AP AV + A Sbjct: 741 -APHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAG 799 Query: 403 PPPSPPV-----------------QAPFSPPASPPVSPSATPPSQAPPSLAAPP------ 439 P+ PV Q + P P A P+ AP + AA P Sbjct: 800 SGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPT 859 Query: 440 ----LQVPPSPPASPPMSPSATPPPQAP----PPLAAPPLQLAKPPPQAPPALATPPLQA 491 +PP + + + P P P P A PP + P QAPP + Q Sbjct: 860 TSIRFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGS--AQL 917 Query: 492 LPSP---PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA----PLLQVPPSPPASPT- 543 LP P + P + A P+ PL +PP P A ++Q+ P P ++P+ Sbjct: 918 LPGKVLVPLAAPSMSVRGGGAGQPL-PLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSG 976 Query: 544 LQAPRRPPT-PGPDTS------VSGPRLTL-------ALAPGPPPPPSRSPSSTLSGPDL 589 L P P T PGP + S R+T AL G P S++ + T GP Sbjct: 977 LVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTS 1036 Query: 590 A---GHSSSATSTP---EELRGYDSGP---EGGAAASPPPDAELAACHPAAWSRGPAPPL 640 + G +S S P + L P G SP P +L PA + G Sbjct: 1037 SVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLP---PACAAPGGPVIT 1093 Query: 641 AFRGAPGAPLPWPPATGPGSADG--LCTIYETEGPESAT------PAPGALDPGPS---- 688 AF AP P P A + T+ + P +AT PAP P P+ Sbjct: 1094 AFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFP 1153 Query: 689 PGTSGGKAAAGAGAGASSRSPK-----QARLGELPLGALQA 724 T+G + A SPK +A + +P+G+ +A Sbjct: 1154 SATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEA 1194 Score = 67.4 bits (163), Expect = 5e-11 Identities = 137/560 (24%), Positives = 183/560 (32%), Gaps = 141/560 (25%) Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVL-----GAAGAVGRKPLAERAGGIGGATIPESAP 75 APG + P SP+ PP V+ G+ PLA+ + + Sbjct: 1066 APGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATS 1125 Query: 76 RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGR------ASGTTRPGPLGQKGLR--- 126 P T P A PA TSP P ++ G A RP P + ++ Sbjct: 1126 TTPPAATILPKGPPAPATATPAP-TSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAI 1184 Query: 127 ----ISAEETVARGKATEAPKRSALSAGARRDTSG-------PTPGTPSPAMARRSRAAG 175 + + E A G+ AP++ R T+ PTP P P + A Sbjct: 1185 ASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTAR 1244 Query: 176 TEVGLPRPAPSARPRPPTEGPRKSVSSASEHST----------------TEPSPAARRRP 219 + LP P A R +GP S S+ T PSPA Sbjct: 1245 SSPPLP---PPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAV 1301 Query: 220 SAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS---------------QPK 264 + GG + + R+ TP A +G + R P + + Sbjct: 1302 APGGSSESSSGRAAGD--TPERKEA-AGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEER 1358 Query: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLA------------TPSPSAPPSPSAPPSL 312 L RP +V P +P L L++SP A T SAP P++P Sbjct: 1359 FAELPEFRPEEVLP-----SPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRK 1413 Query: 313 Q----TLPSPPATPPS---------------QATTSLGS--------PTLQAT------- 338 + S P TP S +A LG +L+ T Sbjct: 1414 MRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRAL 1473 Query: 339 -------HSFLPSPPLSPLATPPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQA 388 H F PS AT QA A P LQ + ATP+ Q Sbjct: 1474 VMQLFQDHGFFPSAQ----ATAAFQARYADIFPSKVCLQLKIRE-VRQKIMQAATPTEQP 1528 Query: 389 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQ-APPSLAAPPLQVPPSPP 447 P A +AP PP A +P SP P T PS + + AAPPL P PP Sbjct: 1529 PGA------EAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPL---PPPP 1579 Query: 448 ASPPMSPS--ATPPPQAPPP 465 S P P P P PPP Sbjct: 1580 ESGPGQPGWEGAPQPSPPPP 1599 Score = 65.5 bits (158), Expect = 2e-10 Identities = 103/382 (26%), Positives = 135/382 (35%), Gaps = 56/382 (14%) Query: 406 SPPVQAPFS---PPASPPVSPSATPP-------SQAPPSLAAPPLQVPPSPPASPPMSPS 455 SP +++ F+ PP P PP AP S A+ P S S + Sbjct: 496 SPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSG 555 Query: 456 ATPPPQAPPPLAAPPLQLAKPPPQAP-PALATPPLQALPSPPASFPGQAPFSPSASLPMS 514 ++ A PL+ PPP A PA + + LP PA+F + P S P Sbjct: 556 TFKAQESGQGSTAGPLR--PPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPG 613 Query: 515 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGP 572 P APP +LQ PP + R P P P +LA G Sbjct: 614 PSVIA---APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP-----------SLAYGA 659 Query: 573 PPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAW 632 P P P++T+ + +STP + P G A + P D A Sbjct: 660 PAAPLSRPAATM----VTNVVRPVSSTPVPIASKPF-PTSGRAEASPNDTAGARTEMGTG 714 Query: 633 SRGPA-PPLAF------RGAPGAPLPWPP-ATGP-----GSADGLCTIYETEGPESATPA 679 SR P PL + + A P P GP G A T P PA Sbjct: 715 SRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPA 774 Query: 680 PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL-------QASVVQHLLS 732 P A+ + G GG AG+GAGA S LG L GAL Q + L Sbjct: 775 PPAVQ-FIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLP 833 Query: 733 RTLLLAAAEGAAGGS-GGGPGG 753 + L +A A A G+ P G Sbjct: 834 QQLQVAPAPAPAPGTKAAAPSG 855 Score = 58.2 bits (139), Expect = 3e-08 Identities = 158/693 (22%), Positives = 215/693 (31%), Gaps = 142/693 (20%) Query: 16 TPAARAPGLLTPRPPGSPRPPPPVT-PAALRVL------GAAGAVGRKPLAERAGGIGGA 68 TP+ P L PG P V P++ R+ G A +G P + +AG + Sbjct: 973 TPSGLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSY 1032 Query: 69 TIPESAPRAGPTRTSRPPASGRGERAP----PAKNTSPGPVSSPGRASGTTRPGPLGQKG 124 GPT + + G P P + P+ +PG+ + P P Sbjct: 1033 ---------GPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSP----- 1078 Query: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184 + A P +A +G+ TS PS A T P Sbjct: 1079 ------QLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAAT 1132 Query: 185 --PSARPRPPTE--GPRKSVSSASEHSTT---------EPSPAARRRPSAG--------- 222 P P P T P SA+ S T PSP A ++ A Sbjct: 1133 ILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSF 1192 Query: 223 ----GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278 G PA R P+ P G P PA P P+ A P + P Sbjct: 1193 EAGASGRPGPAPRQPLEPG-PVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPP 1251 Query: 279 PRKDAAPALGP--------LSSSPLATPS------------PSAPPSPSAPPSLQTLPSP 318 P ++ A GP SSS P PS P+P+ P + S Sbjct: 1252 PAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSS 1311 Query: 319 PA----TPPSQATTSLGS------PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368 TP + G P L+ T + + LS + A P Sbjct: 1312 GRAAGDTPERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEV-----DFEERFAELPEFR 1366 Query: 369 PPSPPASPPLSPLATPSPQA-------PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV 421 P SP L LAT SP+A + L AP P S +S P Sbjct: 1367 PEEVLPSPTLQSLAT-SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPN 1425 Query: 422 SPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL---AAPPLQLAKPPP 478 +P + ++ + + + P L A +QL + Sbjct: 1426 TPKS---AKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHG 1482 Query: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPP 536 P A AT QA + FP + + A P + PP APL P Sbjct: 1483 FFPSAQATAAFQARYAD--IFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPL----P 1536 Query: 537 SPPASPTLQAPRRPPTP--GPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 593 PP + T AP P+P GPD TS S T AP PPPP P Sbjct: 1537 VPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP---------- 1586 Query: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAA 626 G++ P+ + PPP AA Sbjct: 1587 -----------GWEGAPQ---PSPPPPGPSTAA 1605 Score = 38.5 bits (88), Expect = 0.025 Identities = 48/188 (25%), Positives = 72/188 (38%), Gaps = 26/188 (13%) Query: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337 P A+ LG + + S + P S P L P+ PS+A Sbjct: 10 PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQ---------- 59 Query: 338 THSFLPSPPLSPLATPPPQAPPALALPPLQAPP--SPPASPPLSPLAT----PSPQAPNA 391 P P+A+ + P A + PP + A P P AT P P P+ Sbjct: 60 ------QPASHPVASNQSKEPAESAAVAHERPPGGTGSADPERPPGATCPESPGPGPPHP 113 Query: 392 LAVHLLQAPFSPPPSPPVQAPFSPPASPPV-SPSATPPSQAPPSLAAPPLQVPPSPPASP 450 L V +++ PPP+ +A PP P + S + + A S+ +P +Q+P P Sbjct: 114 LGV--VESGKGPPPTTEEEAS-GPPGEPRLDSETESDHDDAFLSIMSPEIQLPLPPGKRR 170 Query: 451 PMSPSATP 458 S SA P Sbjct: 171 TQSLSALP 178 Score = 38.5 bits (88), Expect = 0.025 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 15/108 (13%) Query: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA 286 R + + +ATP P P A A P P G A P TP Sbjct: 1512 REVRQKIMQAATPTEQP----------PGAEAPLPVPPPTGTAAAPAP--TPSPAGGPDP 1559 Query: 287 LGPLSSSPLATPSPSAPPSPSA---PPSLQTLPSPPATPPSQATTSLG 331 P S S A +P PP P + P + P P PP +T + G Sbjct: 1560 TSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQPSPPPPGPSTAATG 1607 Score = 37.7 bits (86), Expect = 0.043 Identities = 41/139 (29%), Positives = 53/139 (38%), Gaps = 13/139 (9%) Query: 389 PNALAV---HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445 P ++AV H L PF P P S P P A+ S+ P AA + PP Sbjct: 29 PRSVAVFPWHSL-VPFLAPSQPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPG 87 Query: 446 PPASP-PMSPSATPPPQAPPPLAAPPLQLAK----PPPQAPPALATPPLQ-ALPSPPASF 499 S P P P++P P PL + + PPP + PP + L S S Sbjct: 88 GTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGEPRLDSETESD 147 Query: 500 PGQA---PFSPSASLPMSP 515 A SP LP+ P Sbjct: 148 HDDAFLSIMSPEIQLPLPP 166 Score = 33.5 bits (75), Expect = 0.82 Identities = 40/165 (24%), Positives = 52/165 (31%), Gaps = 46/165 (27%) Query: 182 RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241 +P PS +P + V+S E + A RP G G SA P Sbjct: 48 QPDPSVQPSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTG-----------SADPER 96 Query: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPS 301 P + P + G P HP LG + S P P+ Sbjct: 97 PPGATCPESPGP--GPPHP--------------------------LGVVESG--KGPPPT 126 Query: 302 APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346 S PP L S + A S+ SP +Q LP PP Sbjct: 127 TEEEASGPPGEPRLDSETESDHDDAFLSIMSPEIQ-----LPLPP 166 Score = 31.2 bits (69), Expect = 4.1 Identities = 22/93 (23%), Positives = 28/93 (30%), Gaps = 7/93 (7%) Query: 80 TRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 139 T T +PP + PP T+ P +P A G P G T Sbjct: 1523 TPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSG-------TAQAAPPL 1575 Query: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 172 P S P+P P P+ A R Sbjct: 1576 PPPPESGPGQPGWEGAPQPSPPPPGPSTAATGR 1608 Score = 30.4 bits (67), Expect = 6.9 Identities = 39/149 (26%), Positives = 51/149 (34%), Gaps = 24/149 (16%) Query: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT-PGPDTS 558 P AP P S+ P +A + P+ PA A RPP G Sbjct: 42 PFLAPSQPDPSVQ-------PSEAQQPASHPVASNQSKEPAESAAVAHERPPGGTGSADP 94 Query: 559 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 618 P T +PGP PP + GP +T EE SGP G P Sbjct: 95 ERPPGATCPESPGPGPPHPLGVVESGKGP--------PPTTEEEA----SGPPG----EP 138 Query: 619 PPDAELAACHPAAWSRGPAPPLAFRGAPG 647 D+E + H A+ +P + PG Sbjct: 139 RLDSETESDHDDAFLSIMSPEIQLPLPPG 167 >gi|110832843 TBP-associated factor 4 [Homo sapiens] Length = 1085 Score = 138 bits (347), Expect = 2e-32 Identities = 163/567 (28%), Positives = 211/567 (37%), Gaps = 66/567 (11%) Query: 160 PGTPSPAMARRSRAAGTEV--GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217 P TP A + A G V G P A A P P EG + + EP PA R Sbjct: 45 PRTPE-VRAAAAGALGNHVVSGSPAGAAGAGPAAPAEG--------APGAAPEPPPAGRA 95 Query: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277 RP GGG QRP S P + PA R P A P P P+ Sbjct: 96 RPG-GGGPQRPGPPSPRRPLVP-AGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPA 153 Query: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQA 337 P A PA GP + + A P P P P P P PA P + T + + L + Sbjct: 154 PAGP-AKPA-GPAALAARAGPGPGPGPGPGPGPG----PGKPAGPGAAQTLNGSAALLNS 207 Query: 338 THSFLPSP------PLSPLATPPPQAP-PALALPPLQAPPSPPASPPLSPLATPSPQAPN 390 H+ P+ P + L P P AP + PP +PPA SP A P+P AP Sbjct: 208 HHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA 267 Query: 391 ALAVHLLQAPFSPPPSPPVQA-PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 A AP PPP+P A P PA PP + A PP A + + P+P A Sbjct: 268 A-------APPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG 320 Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 P S P P A AP ++ P +QA P + P S +A Sbjct: 321 GPAGVSGQPGPGAAAAAPAPGVKAESP---------KRVVQAAPPAAQTLAASGPASTAA 371 Query: 510 SLPMSPL---ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL 566 S+ + P A P P A P A P A Q+ R PT + SG R TL Sbjct: 372 SMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPT----ATTSGIRATL 427 Query: 567 ---ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-GYDSGPEGGAAASPPPDA 622 LAP P PP ++P++ + G + + L + + A A P Sbjct: 428 TPTVLAPRLPQPP-QNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQT 486 Query: 623 ELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGA 682 +A PA + P ++ APG P+ T TI + T P A Sbjct: 487 TMAP-RPATPTSAPPVQISTVQAPGTPIIARQVTP-------TTIIKQVSQAQTTVQPSA 538 Query: 683 L---DPGPSPGTSGGKAAAGAGAGASS 706 PG P G AA A G ++ Sbjct: 539 TLQRSPGVQPQLVLGGAAQTASLGTAT 565 Score = 113 bits (282), Expect = 8e-25 Identities = 152/521 (29%), Positives = 192/521 (36%), Gaps = 63/521 (12%) Query: 8 AKAGAAARTPAARA-PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 A A PA RA PG P+ PG P P P+ PA A A +P E + G Sbjct: 82 APGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAG----PAPPAAKLRPPPEGSAGSC 137 Query: 67 GATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 126 +A AGP PA G A A+ PGP PG G PGP G Sbjct: 138 APVPAAAAVAAGPEPAPAGPAKPAGPAALAAR-AGPGPGPGPGPGPG---PGPGKPAGP- 192 Query: 127 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE--VGLPRPA 184 A +T+ G A A + +GP P P A T VG P Sbjct: 193 -GAAQTL-NGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250 Query: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 244 A P PP P + +A+ P+PA RP PA ++ A P + A Sbjct: 251 APAAPSPPA-APAPAAPAAAP-PPPPPAPATLARPPG-----HPAGPPTAAPAVPPPAAA 303 Query: 245 RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP 304 ++G SA P APA P+ P G+ Q P AAPA G + SP Sbjct: 304 QNGGSAGAAP-APA-PAAGGPAGVSG----QPGPGAAAAAPAPGVKAESPKRVVQ----- 352 Query: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364 +APP+ QTL + + P S A + + PT+Q LPSP A PP AP Sbjct: 353 --AAPPAAQTLAA--SGPASTAASMVIGPTMQGA---LPSP-----AAVPPPAPGTPTGL 400 Query: 365 PLQAPPSPPASPPLSPLATPS----PQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420 P A + S +P AT S P LA L Q P +P Q P Sbjct: 401 PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLP-------- 452 Query: 421 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 480 P L P Q A P T P+ P +APP+Q++ Sbjct: 453 --PGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPG 510 Query: 481 PPALATPPLQALPSPPASFPGQA--PFSPSASLPMSPLATP 519 P +A Q P+ QA PSA+L SP P Sbjct: 511 TPIIAR---QVTPTTIIKQVSQAQTTVQPSATLQRSPGVQP 548 Score = 108 bits (269), Expect = 3e-23 Identities = 110/371 (29%), Positives = 139/371 (37%), Gaps = 24/371 (6%) Query: 354 PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413 P A A P + P PP + A P P + P P P A Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126 Query: 414 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 PP A P+ A + P P+ PA P + P P P P Sbjct: 127 RPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGP 186 Query: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMSPLATPPP--QAPPVL-- 527 KP L S A+ P + + P+A LP+ A P Q PP + Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA 246 Query: 528 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG-PPPPPSRSPSSTLSG 586 AAP PSPPA+P AP P P P TLA PG P PP+ +P+ Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-----TLARPPGHPAGPPTAAPAVPPPA 301 Query: 587 PDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 646 G S+ A P G GP G + P P A AA PA + +P + AP Sbjct: 302 AAQNGGSAGAAPAPAPAAG---GP-AGVSGQPGPGA--AAAAPAPGVKAESPKRVVQAAP 355 Query: 647 GAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGA 704 A A+GP S I T + A P+P A+ P P+PGT G K AAGA + Sbjct: 356 PAAQTL-AASGPASTAASMVIGPT--MQGALPSPAAVPP-PAPGTPTGLPKGAAGAVTQS 411 Query: 705 SSRSPKQARLG 715 SR+P G Sbjct: 412 LSRTPTATTSG 422 Score = 80.9 bits (198), Expect = 4e-15 Identities = 96/339 (28%), Positives = 122/339 (35%), Gaps = 49/339 (14%) Query: 443 PPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP---PQ--APPALATPPLQALPSPPA 497 P + P +P+ P AP P PP A+P PQ PP+ P + A P+PPA Sbjct: 67 PAGAAGAGPAAPAEGAPGAAPEP---PPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPA 123 Query: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSPPASPTLQAPRRPPTPGPD 556 + P + S P P A V A P P+ PA P A R P PGP Sbjct: 124 AKLRPPPEGSAGS------CAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG 177 Query: 557 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE----- 611 GP PGP P + TL+G +S A + L ++GP Sbjct: 178 PG-PGP------GPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSL--VNNGPAALLPL 228 Query: 612 ------GGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLC 665 G +PP A PAA P+PP A AP AP PP P A Sbjct: 229 PKPAAPGTVIQTPPFVGAAAPPAPAA----PSPPAA--PAPAAPAAAPPPPPPAPATLAR 282 Query: 666 TIYETEGPESATPA---PGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722 GP +A PA P A G S G + A A G S P P + Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGV 342 Query: 723 QASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTG 761 +A + ++ AA A + GP V G Sbjct: 343 KAESPKRVVQ-----AAPPAAQTLAASGPASTAASMVIG 376 Score = 69.7 bits (169), Expect = 1e-11 Identities = 91/320 (28%), Positives = 107/320 (33%), Gaps = 40/320 (12%) Query: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519 P+ P AA L PA A A P+ A PG AP P A P Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGA--PGAAPEPPPAGRARPGGGGP 102 Query: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579 PP PL+ P+PPA A RPP G S + A+A GP P P+ Sbjct: 103 QRPGPPSPRRPLVPAGPAPPA-----AKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPA-G 156 Query: 580 PSSTLSGPDLAGHSSSATST-----PEELRGYDSGPEGGAAASPPPDAELAACHPAAW-- 632 P+ LA + P G +GP GAA + A L H AA Sbjct: 157 PAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGP--GAAQTLNGSAALLNSHHAAAPA 214 Query: 633 ----SRGPAP--PLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG 686 + GPA PL APG + PP G + P A PA P Sbjct: 215 VSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPP 274 Query: 687 PSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGG 746 P+P T AG P A P A Q A A A Sbjct: 275 PAPATLARPPGHPAG-------PPTAAPAVPPPAAAQNGGS----------AGAAPAPAP 317 Query: 747 SGGGPGGAEGGGVTGGARAA 766 + GGP G G G A AA Sbjct: 318 AAGGPAGVSGQPGPGAAAAA 337 Score = 59.7 bits (143), Expect = 1e-08 Identities = 128/582 (21%), Positives = 179/582 (30%), Gaps = 137/582 (23%) Query: 10 AGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGA--AGAVGRKPL-AERAGGIG 66 A AAA P AP L RPPG P PP PA A G+ G P A AGG Sbjct: 265 APAAAPPPPPPAPATLA-RPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA 323 Query: 67 GAT-----------------------IPESAPRAGPTRTSRPPASGRGERA--PPAKNTS 101 G + + ++AP A T + PAS P + Sbjct: 324 GVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL 383 Query: 102 PGPVSSPGRASGTTRPGPLGQ----------------KGLRISAEETVARGKATEAPKRS 145 P P + P A GT P G G+R + TV + + P+ Sbjct: 384 PSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNP 443 Query: 146 ALSAGAR--------RDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197 + R +G P A+A+ A + P+ + RP PT P Sbjct: 444 TNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQ---PQTTMAPRPATPTSAPP 500 Query: 198 KSVSS----------------------ASEHSTTEPSPAARRRPSAG-----GGLQRPAS 230 +S+ + +T +PS +R P GG + AS Sbjct: 501 VQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560 Query: 231 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK--------------GLQALRPP-- 274 +++A +P R+ P A T A + K G Q+ Sbjct: 561 LG-TATAVQTGTPQRTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAAN 619 Query: 275 ------QVTPPRKDAAPALGPLSSSPLATPSPSAPP------------SPSAPPSLQTLP 316 + + +A L ++P P P +P + +Q Sbjct: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSAAFIQQSQ 679 Query: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALAL-PPLQAPPSPPAS 375 P P SQATT+L + L + S + + PP L+L P Q Sbjct: 680 QQPPPPTSQATTALTAVVLSS--SVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQ 737 Query: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435 P +PL P P AL PP Q P P T P Q + Sbjct: 738 P--TPLVIQQPPKPGAL--------IRPPQVTLTQTPMVALRQPHNRIMLTTPQQ----I 783 Query: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477 PLQ P P P + P AA K P Sbjct: 784 QLNPLQ--PVPVVKPAVLPGTKALSAVSAQAAAAQKNKLKEP 823 Score = 48.9 bits (115), Expect = 2e-05 Identities = 59/184 (32%), Positives = 64/184 (34%), Gaps = 33/184 (17%) Query: 590 AGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAP 649 A H A TPE +R +G G S P A GPA P GAPGA Sbjct: 38 AHHHHLAPRTPE-VRAAAAGALGNHVVSGSPAGAAGA--------GPAAPA--EGAPGAA 86 Query: 650 LPWPPATGPGSADGLCTIYETEGPES-------ATPAPGALDPGPSPGTSGGKAAAGAGA 702 P PP G G + GP S A PAP A P P S G A A Sbjct: 87 -PEPPPAGRARPGGGGP--QRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAA 143 Query: 703 GASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGG 762 A + P+ A G A LAA G G G GPG G G G Sbjct: 144 AAVAAGPEPAPAGPAKPAGPAA------------LAARAGPGPGPGPGPGPGPGPGKPAG 191 Query: 763 ARAA 766 AA Sbjct: 192 PGAA 195 >gi|122937496 WAS/WASL interacting protein family, member 3 [Homo sapiens] Length = 483 Score = 138 bits (347), Expect = 2e-32 Identities = 134/432 (31%), Positives = 179/432 (41%), Gaps = 49/432 (11%) Query: 180 LPRPAP--SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSA 237 LP P P A P PP P S ++S +A G R ++ SA Sbjct: 11 LPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSA 70 Query: 238 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP-RKDAAPALGPLSSSPLA 296 + S + G+ + P L A P + P ++D A G P + Sbjct: 71 PQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG--GKTGQGPGS 128 Query: 297 -TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355 PSP P + P + PPA+P LG+ T +A + +PP + PPP Sbjct: 129 RAPSPRLPNKTISGPLI-----PPASP------RLGN-TSEAHGAARTAPPRPNVPAPPP 176 Query: 356 QAPPALALPPLQAPPSPPASPPLSPLATP-SPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414 PP PP PP P +SP +PL +P P L V P +PPP PP Sbjct: 177 PTPPPP--PPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPP---- 230 Query: 415 PPASPPVSPSATPPSQA-PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473 PP PP+ P++ +A P LA PL +PP PP P + P P +A P A P Q Sbjct: 231 PPTPPPLPPASVLSDKAVKPQLA--PLHLPPIPPPLPLLPPCGYPGLKAEP---ASPAQD 285 Query: 474 AK----PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA- 528 A+ PPP PP + P +LP+PP PG S S + P P +P QAPP A Sbjct: 286 AQEPPAPPPPLPPYASCSPRASLPAPP--LPGVN--SSSETPPPLPPKSPSFQAPPQKAG 341 Query: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 588 A L PP+PP S +R PG P PP PP+RSP++ LS Sbjct: 342 AQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNP---------PPAPPARSPTTELSSKS 392 Query: 589 LAGHSSSATSTP 600 + + T P Sbjct: 393 QQATAWTPTQQP 404 Score = 110 bits (274), Expect = 7e-24 Identities = 134/451 (29%), Positives = 165/451 (36%), Gaps = 85/451 (18%) Query: 17 PAARAPGLLTPRPP-GSPRPPPPVTPAA---LRVLGAAGAVGRKP-LAERAGGIGGATIP 71 P P L P PP G+P PPPP P L A GR LA+ G + Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVT 63 Query: 72 ESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 131 + R+ P S + G + + S P A G P GQ+ Sbjct: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQR-------- 115 Query: 132 TVARGKATEAPKRSALSAGARRDT-SGPTPGTPSPAMARRSRAAG-TEVGLPRPAPSARP 189 VA GK + P A S T SGP SP + S A G PRP A P Sbjct: 116 DVAGGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPA-P 174 Query: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249 PPT P P P PS+ S TPL SP GP Sbjct: 175 PPPTPPP-------------PPPPLPPPLPSS------------SPIKTPLVSP--PGPL 207 Query: 250 ARG-----TPRAPAHPSQPKPKGLQALRPPQVTPP---------RKDAAPALGPLSSSPL 295 +G P P P P P PP TPP K P L PL P+ Sbjct: 208 TKGNLPVVAPPVPCAPPPPPP-------PPPPTPPPLPPASVLSDKAVKPQLAPLHLPPI 260 Query: 296 ATPSPSAPP--------SPSAP-PSLQTLPSPPATPPSQAT----TSLGSPTLQATHSFL 342 P P PP P++P Q P+PP P A+ SL +P L +S Sbjct: 261 PPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSS 320 Query: 343 PSPPLSPLATPPPQAPPALA-LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 401 +PP P +P QAPP A L APP+PP S P L P A L Sbjct: 321 ETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF--LQKKRHGRPGAGGGKL----- 373 Query: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAP 432 +PPP+PP ++P + +S +A P+Q P Sbjct: 374 NPPPAPPARSPTTELSSKSQQATAWTPTQQP 404 Score = 104 bits (259), Expect = 4e-22 Identities = 114/401 (28%), Positives = 146/401 (36%), Gaps = 101/401 (25%) Query: 342 LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ--- 398 +P PP P PPP PP L PP P +PP S S L P+ +AL + Q Sbjct: 1 MPVPPPPPPPLPPP--PPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTR 58 Query: 399 ----------------------------APFSPPPSPPVQAPFSPPASPPVSPSAT---- 426 A +PP P + P+ Sbjct: 59 LRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVA 118 Query: 427 -------PPSQAP-PSLAAPPLQVPPSPPASPPMSPSA-------TPPPQAPPPLAAPPL 471 P S+AP P L + P PPASP + ++ T PP+ P PP Sbjct: 119 GGKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPT 178 Query: 472 QLAKPPPQAPPALATPPLQA-LPSPP-----ASFPGQAPFSPSASLPMSPLATPPPQAPP 525 PPP PP ++ P++ L SPP + P AP P A P P PPP PP Sbjct: 179 PPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCA--PPPPPPPPPPTPPP 236 Query: 526 VLAAPL------------LQVPPSPPASPTLQAPRRPPT--PGPDTSVSGPRLTLALAPG 571 + A + L +PP PP P L PP PG + P P Sbjct: 237 LPPASVLSDKAVKPQLAPLHLPPIPPPLPLL-----PPCGYPGLKAEPASPAQDAQEPPA 291 Query: 572 PPPP----PSRSPSSTLSGPDLAGHSSSATS---TPEELRGYDSGPE-GGAAASPPPDAE 623 PPPP S SP ++L P L G +SS+ + P + + + P+ GA A P P Sbjct: 292 PPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAP--- 348 Query: 624 LAACHPAAWSRGPAPPLAFRGAPGA------PLPWPPATGP 658 PA P G PGA P P PPA P Sbjct: 349 -----PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSP 384 Score = 70.1 bits (170), Expect = 8e-12 Identities = 97/389 (24%), Positives = 126/389 (32%), Gaps = 111/389 (28%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG 63 +RD A G + P +RAP +PR P P + PA+ R Sbjct: 114 QRDVA-GGKTGQGPGSRAP---SPRLPNKTISGPLIPPASPR------------------ 151 Query: 64 GIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123 +G + A R P R + P PP P P SSP + + PGPL + Sbjct: 152 -LGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKG 210 Query: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183 L + A P P P P P P Sbjct: 211 NLPVVAP---------------------------PVPCAPPPPP-------------PPP 230 Query: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 P+ P PP +S +P A P L PL P Sbjct: 231 PPTPPPLPP--------ASVLSDKAVKPQLAPLHLPPIPPPL-------------PLLPP 269 Query: 244 ARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303 P + P +PA +Q P PP PP +P +S A P P Sbjct: 270 C-GYPGLKAEPASPAQDAQEPP------APPPPLPPYASCSP-----RASLPAPPLPGVN 317 Query: 304 PSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ----APP 359 S PP P PP +P QA P +A LP+PP P + P Q P Sbjct: 318 SSSETPP-----PLPPKSPSFQA------PPQKAGAQALPAPPAPPGSQPFLQKKRHGRP 366 Query: 360 ALALPPLQAPPSPPASPPLSPLATPSPQA 388 L PP+PPA P + L++ S QA Sbjct: 367 GAGGGKLNPPPAPPARSPTTELSSKSQQA 395 Score = 62.4 bits (150), Expect = 2e-09 Identities = 106/416 (25%), Positives = 138/416 (33%), Gaps = 131/416 (31%) Query: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL---------- 484 + PP PP PP PP+ PPP A PP++ L + P+ AL Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSA-PPVSTDTSSLRRADPKGRSALLADIQQGTRL 59 Query: 485 ---------ATPPLQA----------------LPSPP-------ASFP------------ 500 + P +++ +PP FP Sbjct: 60 RKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119 Query: 501 ---GQAPFS--PSASLPMSPLATP--PPQAPPV-----------LAAPLLQVPPSPPASP 542 GQ P S PS LP ++ P PP +P + A P VP PP +P Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179 Query: 543 TLQAPRRPP--------------TPGPDTS----VSGPRLTLALAPGPPPPPSR----SP 580 P PP PGP T V P + A P PPPPP P Sbjct: 180 PPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPP 239 Query: 581 SSTLSG----PDLAGHSSSATSTPEEL------RGYDSGPEGGA------AASPPPDAEL 624 +S LS P LA P L G + P A A PPP Sbjct: 240 ASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPY 299 Query: 625 AACHPAAWSRGPAPPL-AFRGAPGAPLPWPPAT----GPGSADGLCTIYETEGPESATP- 678 A+C P A PAPPL + P P PP + P G + P + P Sbjct: 300 ASCSPRA--SLPAPPLPGVNSSSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPF 357 Query: 679 -------APGA----LDPGPS-PGTSGGKAAAGAGAGASSRSPKQARLGELPLGAL 722 PGA L+P P+ P S + A++ +P Q G+L G+L Sbjct: 358 LQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAWTPTQQPGGQLRNGSL 413 >gi|146219843 Snf2-related CBP activator protein [Homo sapiens] Length = 3230 Score = 137 bits (346), Expect = 3e-32 Identities = 189/603 (31%), Positives = 239/603 (39%), Gaps = 84/603 (13%) Query: 13 AARTPAARAPGLLTPRPPGSP-RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 A R P++ P +L PRP +P R P P A + V +PL + + Sbjct: 1330 APRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLV--RPLLKLVHS-PSPEVS 1386 Query: 72 ESAPRAGPTRTSRP---PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 SAP A P S P P+S G + P + P++SP +T PL L IS Sbjct: 1387 ASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASP---VSSTVSVPL-SSSLPIS 1442 Query: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTP-SPAMARRSRAAGTEVGLPRPAPSA 187 T+ AP +SA SGP T +P +A P A Sbjct: 1443 VPTTLP--APASAPLTIPISAPLTVSASGPALLTSVTPPLA--------------PVVPA 1486 Query: 188 RPRPPTEGPRKSVSSASEHS---TTEPSPAARRRPSAGGGLQRPASR--SLSSSATPLSS 242 P PP+ P + SAS + T PS ++ + P L +S L+S+ P S Sbjct: 1487 APGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACS 1546 Query: 243 PARSGPSARGTPRAPAHPSQPKPKGLQA--LRPPQ------VTPPRKDAAP---ALGPLS 291 P SA +P PS P P QA L P TP AAP L P Sbjct: 1547 PVLVPASALASP----FPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSP 1602 Query: 292 SSPLATPSPSAPPSPSAPPSLQT--LPSPPATPPSQATTSLGS--------PTL--QATH 339 + PLA P P PSP A P L + P P P S TSL S P L +T Sbjct: 1603 APPLA-PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQ 1661 Query: 340 SFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS-PLATPSPQAPNALAVHLLQ 398 + LP+P SPL P P + LAL P AP +SP + L T +PQ P L Sbjct: 1662 TMLPAPVPSPL--PSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT 1719 Query: 399 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 458 S P+P +P PP+ P+ T S AP APPL P SP P Sbjct: 1720 PASSLVPTPAQTLSLAP--GPPLGPTQT-LSLAP----APPL-APASPVGPAPAHTLTLA 1771 Query: 459 PPQAPPPLAAP-PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 P + L AP +Q P P L Q L PAS Q+P S ++SL +S Sbjct: 1772 PASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAS--TQSPASQASSLVVSASG 1829 Query: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577 P PV L V P + TL++ P P TS GPR PPPP Sbjct: 1830 AAP---LPVTMVSRLPVSKDEPDTLTLRS-GPPSPPSTATSFGGPR-----PRRQPPPPP 1880 Query: 578 RSP 580 RSP Sbjct: 1881 RSP 1883 Score = 130 bits (327), Expect = 5e-30 Identities = 208/704 (29%), Positives = 271/704 (38%), Gaps = 105/704 (14%) Query: 31 GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGR 90 G PRP V+ A G+ L + + A I AP GPT S P+S Sbjct: 1229 GQPRP------LQRNVVHLVSAGGQHHLISQPAHV--ALIQAVAPTPGPTPVSVLPSS-- 1278 Query: 91 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAG 150 P+ +P +S P A+ P + G+ R T P L+ Sbjct: 1279 ----TPSTTPAPTGLSLP-LAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPP---LAPA 1330 Query: 151 ARRDTSG-PTPGTPSPAMARRSRAAGT--EVGLPRPAPS-ARPRPP---TEGPRKSVSSA 203 R +SG P P P + T P P P+ RP + P S S+ Sbjct: 1331 PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAP 1390 Query: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLS-SSATPLSSPARSGPSARGTPRAPAHPSQ 262 T SP PS+ L PAS + +++PL+SP S T P S Sbjct: 1391 GAAPLTISSPL--HVPSS---LPGPASSPMPIPNSSPLASPVSS------TVSVPLSSSL 1439 Query: 263 PKPKGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPSPSAPP-----SPSAPPSLQT 314 P ++ P APA PL+ S+PL T S S P +P P + Sbjct: 1440 P------------ISVPTTLPAPASAPLTIPISAPL-TVSASGPALLTSVTPPLAPVVPA 1486 Query: 315 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ---APPALALPPLQAPPS 371 P PP+ PS A+ S + TL +P LS TP AP + +P L + + Sbjct: 1487 APGPPSLAPSGASPSASALTL----GLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVA 1542 Query: 372 PPASP---PLSPLATPSPQAPN-ALAVHLLQAPFSPPPSPPVQAPFSPPASPP---VSPS 424 P SP P S LA+P P APN A A L AP S S + P +P A+P ++PS Sbjct: 1543 PACSPVLVPASALASPFPSAPNPAPAQASLLAPAS-SASQALATPLAPMAAPQTAILAPS 1601 Query: 425 ATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATP--------PPQAPPPLAAPPLQL 473 PP P LA P P S P M+PS+TP P AP P+ AP Sbjct: 1602 PAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQ 1661 Query: 474 AKPPPQAPPALATP-PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532 P P L +P Q L PA P SPS +L L T PQ P L Sbjct: 1662 TMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTL---SLGTGNPQGP--FPTQTL 1716 Query: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR----SPSSTLSGPD 588 + P+ PT A PGP GP TL+LAP PP P+ +P+ TL+ Sbjct: 1717 SLTPASSLVPT-PAQTLSLAPGPPL---GPTQTLSLAPAPPLAPASPVGPAPAHTLT--- 1769 Query: 589 LAGHSSSAT-STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS-RGPAPPLAFRGAP 646 LA SSSA+ P ++ P P LA + S A L + Sbjct: 1770 LAPASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASG 1829 Query: 647 GAPLPWPPATG-PGSADGLCTIYETEGPESATPAPGALDPGPSP 689 APLP + P S D T+ GP S P+ GP P Sbjct: 1830 AAPLPVTMVSRLPVSKDEPDTLTLRSGPPS-PPSTATSFGGPRP 1872 Score = 117 bits (294), Expect = 3e-26 Identities = 174/650 (26%), Positives = 234/650 (36%), Gaps = 149/650 (22%) Query: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217 PTPG P P + S P P++RP P P +S S PSP Sbjct: 1036 PTPG-PVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVL-PSPLG-- 1091 Query: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277 G RP + +LS + TP AP S P G +L P Sbjct: 1092 ---VLSGTSRPPTPTLS---------------LKPTPPAPVRLSPAPPPGSSSLLKPLTV 1133 Query: 278 PPRKDAAPALGPLSSSPLATPSPSAPPSPS-APPSLQTLPSPPATPPSQATTSLGSPT-- 334 PP PA +S+ AT + +A P+P+ AP L P A PS S+G Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASL 1193 Query: 335 -----------------LQATHSFLPSPPLSPLATPPPQ--------------------A 357 +Q L + LA P+ Sbjct: 1194 AQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQ 1253 Query: 358 PPALALPPLQAPPSPPASPPLSPLATPS-PQAPNALAVHLLQAPFSPPPSPPV------- 409 P +AL AP P + P +TPS AP L++ P + PP Sbjct: 1254 PAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSL-----PLAANQVPPTMVNNTGV 1308 Query: 410 ------QAPFSP-PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462 QAP PP++P+ PPS P++ P + P +P + + P P Sbjct: 1309 VKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMP-- 1366 Query: 463 PPPLAAPPLQLAKPP--------PQAPPALATPPL---QALPSP-------PASFPGQAP 504 P L P L+L P P A P + PL +LP P P S P +P Sbjct: 1367 TPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASP 1426 Query: 505 FSPSASLPMS-------PLATPPPQAPPV---LAAPL--------LQVPPSPPASPTLQA 546 S + S+P+S P P P + P+ ++APL L +PP +P + A Sbjct: 1427 VSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPA 1486 Query: 547 PRRPPTPGPD-TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 605 PP+ P S S LTL LA P S++P L + H ST Sbjct: 1487 APGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACS 1546 Query: 606 YDSGPEGGAAASP------PPDAELAACHPA-AWSRGPAPPLAFRGAPG----APLPWPP 654 P A ASP P A+ + PA + S+ A PLA AP AP P PP Sbjct: 1547 PVLVP-ASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPP 1605 Query: 655 -------ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697 A PG+A L + S TP P + P +PGTS A+ Sbjct: 1606 LAPLPVLAPSPGAAPVLAS--------SQTPVP-VMAPSSTPGTSLASAS 1646 Score = 90.1 bits (222), Expect = 7e-18 Identities = 123/439 (28%), Positives = 159/439 (36%), Gaps = 78/439 (17%) Query: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP---PSP 372 P P T S+ + T A H+ + S + T PP+ PA P AP P+P Sbjct: 2388 PERPGTRVSERLRGARAETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTP 2447 Query: 373 PASPPLSPLATPSP-------QAPNA---LAVHLLQAPFSPPPS--PPVQAPFSPPASPP 420 ++P P P P APN L VH+L +P PPPS PP SP +PP Sbjct: 2448 ASAPAAIPALVPVPVSAPVPISAPNPITILPVHILPSP--PPPSQIPPCS---SPACTPP 2502 Query: 421 VSPSATPPSQAPPSLAAPPLQVPPSP----PASPPMSPSATPPPQAPPP--------LAA 468 P+ TPP P A L P SP P S P+S S T P P LA+ Sbjct: 2503 --PACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALAS 2560 Query: 469 P-PLQLAKPPPQAPPALA-TPPLQALPSPPASFP------GQAPFSPSASLPMSPLATPP 520 P L+LA +L+ PP LP P P +PS +L + Sbjct: 2561 PESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQ 2620 Query: 521 PQAPPVLA-------------APL-------LQVPPSPPASPTLQAPRRPPTPGPD---- 556 Q P A PL L++PPS + LQ P + Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEA 2680 Query: 557 -TSVSGPRLTLALAPGPPPPPSRSPSSTLS--GPDLAGHSSSATSTPEELRGYDSG---- 609 T S P L PS S S+T S GP A TS E+RG +G Sbjct: 2681 KTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQ 2740 Query: 610 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 669 P G P + R RGA +P T ++ G ++ Sbjct: 2741 PPGPKVLRKLPGRLVTVVEEKELVRRRRQQ---RGAASTLVPGVSET--SASPGSPSVRS 2795 Query: 670 TEGPESATPAPGALDPGPS 688 GPES+ P G + PS Sbjct: 2796 MSGPESSPPIGGPCEAAPS 2814 Score = 87.4 bits (215), Expect = 5e-17 Identities = 167/664 (25%), Positives = 232/664 (34%), Gaps = 151/664 (22%) Query: 209 TEPSPAARRRP--SAGGGLQRPASRSLSSSATPLSSP-ARSGPSARGTPRAPAHPSQPKP 265 T P P R +P + +P + + +++P A GP P P +QP P Sbjct: 979 TAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAPLGPVPVRPPPGPELSAQPTP 1038 Query: 266 KGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQ 325 + + P + A P L P S P P P+ + P Q LPSP Sbjct: 1039 GPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLP--QVLPSPLGV--LS 1094 Query: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS---PPASPPLS--- 379 T+ +PTL S P+PP +P P + L PL PP PPA+ + Sbjct: 1095 GTSRPPTPTL----SLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTT 1150 Query: 380 ---------PLATPSPQ----APNALA-------------VHLLQAPF-----SPPPSPP 408 P TP+PQ +P+ A L Q P S P + Sbjct: 1151 TATATTTAVPAPTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQ 1210 Query: 409 VQA-------------------PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 +Q P VS + P+ A V P+P + Sbjct: 1211 IQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPT 1270 Query: 450 P-PMSPSATPPPQAPPPLAAPPLQLAKPPP--------------QAPPALAT--PPLQAL 492 P + PS+TP P + PL + PP QAP T PPL Sbjct: 1271 PVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPA 1330 Query: 493 PSPPAS-FPGQAPFSPSASLPMSPLATP------PPQAPPVLAAPLLQVPPSPPASPTLQ 545 P PP+S P A +P +L L TP P P L PLL++ SP + Sbjct: 1331 PRPPSSGLP--AVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSAS 1388 Query: 546 APRRPPTPGPDTSVSGPRLTLALAPGPP----PPPSRSP-----SSTLSGPDLAGHSSSA 596 AP P ++S P + PGP P P+ SP SST+S P SS Sbjct: 1389 APGAAP-----LTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVP---LSSSLP 1440 Query: 597 TSTPEELRGYDSGPEGGAAASP---------------PPDAELAACHPAAWSRGP----- 636 S P L S P ++P PP A + P S P Sbjct: 1441 ISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASP 1500 Query: 637 -----------APPLAFRGAPGAPLPWPPATG--PG---SADGLCTIYETEGPESATPAP 680 AP L+ PG PL P + PG + C+ A+P P Sbjct: 1501 SASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFP 1560 Query: 681 GALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAA 740 A +P P+ + A++ + A A+ +P A P A+ A L+ +LA + Sbjct: 1561 SAPNPAPAQASLLAPASSASQALATPLAPMAA-----PQTAILAPSPAPPLAPLPVLAPS 1615 Query: 741 EGAA 744 GAA Sbjct: 1616 PGAA 1619 Score = 78.2 bits (191), Expect = 3e-14 Identities = 146/569 (25%), Positives = 195/569 (34%), Gaps = 106/569 (18%) Query: 12 AAARTPAARAPGLLTP-RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLA-ERAGGIGGAT 69 +A T +A P LLT PP +P P P +L GA+ + L A + + Sbjct: 1460 SAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQ 1519 Query: 70 IPESAPRAGPTRTSRP---------------PASGRGERAPPAKNTSPG------PVSSP 108 P PT + P PAS P A N +P P SS Sbjct: 1520 TPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSA 1579 Query: 109 GRASGTT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGP------TPG 161 +A T P Q + + AP A A T P TPG Sbjct: 1580 SQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG 1639 Query: 162 T------PSPAMARRSRAAGTEVGLPRPAPSARPRP---------PTEGPRKSVSSASEH 206 T P PA + T+ LP P PS P P P P SS S+ Sbjct: 1640 TSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQT 1699 Query: 207 ------STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP 260 + P P + L +++LS + P P ++ A P APA P Sbjct: 1700 LSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASP 1759 Query: 261 SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA-TPSPSAPPSPSAPPSLQTLPSPP 319 P P L P +A L P S L +P+P P+A +L P+ Sbjct: 1760 VGPAPAHTLTLAPAS------SSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPAST 1813 Query: 320 ATPPSQATTSL----GSPTLQATH-SFLP----SPPLSPLATPPPQAPPALALP-----P 365 +P SQA++ + G+ L T S LP P L + PP +PP+ A P Sbjct: 1814 QSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPP-SPPSTATSFGGPRP 1872 Query: 366 LQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQ--------AP--------FSPPPSPP 408 + PP PP SP L L + + + Q AP F P P Sbjct: 1873 RRQPPPPPRSPFYLDSLEEKRKRQRSERLERIFQLSEAHGALAPVYGTEVLDFCTLPQP- 1931 Query: 409 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ--------------VPPSPPASPPMSP 454 V +P P + P P+ ++A P Q V P A PP Sbjct: 1932 VASPIGPRSPGPSHPTFWTYTEAAHRAVLFPQQRLDQLSEIIERFIFVMPPVEAPPPSLH 1991 Query: 455 SATPPPQAPPPLAAPPLQLAKPP-PQAPP 482 + PPP P AA QLA P+A P Sbjct: 1992 ACHPPPWLAPRQAAFQEQLASELWPRARP 2020 Score = 77.8 bits (190), Expect = 4e-14 Identities = 183/797 (22%), Positives = 245/797 (30%), Gaps = 183/797 (22%) Query: 27 PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86 PRP PRP P PAA+ L P+ + +P + P + PP Sbjct: 2437 PRPAPRPRPTPASAPAAIPALVPVPVSAPVPI---SAPNPITILPVHILPSPPPPSQIPP 2493 Query: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP--LGQKGLRISAE----------ETVA 134 S PPA P P + T P LG + ISA E Sbjct: 2494 CSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAEL 2553 Query: 135 RGKATEAPKRSALSAGARRDTS-------------------------GPTPGTPSPAMAR 169 +A +P+ L++ A +TS TP PS + Sbjct: 2554 CAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEA 2613 Query: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP- 228 S G E P A EG + + + P AA P LQ P Sbjct: 2614 GSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEP-----LQEPL 2668 Query: 229 ----ASRSLSSSATPLSSPAR----------------------SGPSARGTPR------- 255 S L+ + TP SSP + GPS PR Sbjct: 2669 EADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRRTSADV 2728 Query: 256 -----APAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309 P QP PK L+ L VT + +T P + ++P Sbjct: 2729 EIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASP 2788 Query: 310 --PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP------------------ 349 PS++++ P ++PP +G P A S LP+PP P Sbjct: 2789 GSPSVRSMSGPESSPP------IGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPE 2842 Query: 350 ------LATPPPQAPPALALPPLQAPPSPPA-----SPPLSPL------ATPSPQAPNAL 392 LA PP PP + A P S L A P P P L Sbjct: 2843 NGDGALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVP-GPETL 2901 Query: 393 AV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS-PPAS 449 V +L+ P P P P P +P +SP PP A L +P + A Sbjct: 2902 IVADPVLEPQLIPGPQPLGPQPVHRP-NPLLSPVEKRRRGRPPK--ARDLPIPGTISSAG 2958 Query: 450 PPMSPSATPPPQAPPPLA-APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPS 508 S S T PP P PL PPL + P A A + SPP G+ P +P Sbjct: 2959 DGNSESRTQPPPHPSPLTPLPPLLVC---PTATVANTVTTVTISTSPPKRKRGRPPKNP- 3014 Query: 509 ASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568 +P P PVL V S Q + + G + G R Sbjct: 3015 --------PSPRPSQLPVLDRDSTSVLESCGLGRRRQPQGQGESEGSSSDEDGSR----- 3061 Query: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATST----PEELRGYDSGPEG------------ 612 P +R L + G S + ++L DSGP G Sbjct: 3062 ------PLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADSGPGGLELTPPVVSLTP 3115 Query: 613 --------GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664 + PP + E A G +P LA RG P P P ++ Sbjct: 3116 KLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQPPSPLGPEGSVEESEAE 3175 Query: 665 CTIYETEGPESATPAPG 681 + E EG + PG Sbjct: 3176 ASGEEEEGDGTPRRRPG 3192 Score = 74.7 bits (182), Expect = 3e-13 Identities = 108/456 (23%), Positives = 152/456 (33%), Gaps = 65/456 (14%) Query: 340 SFLPSPPLS-------PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392 +FLP LS A PP P + + + P + + +P+AP Sbjct: 962 TFLPRHRLSRRVLLEVATAPDPPPRPKPVKMKVNRMLQPVPKQEGRTVVVVNNPRAP--- 1018 Query: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452 L P PPP P + A +P P V P++ S +P P PP P PP+ Sbjct: 1019 ---LGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPL 1075 Query: 453 SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP 512 P++ PQ P ++PP TP L P+PPA P +S Sbjct: 1076 QPNSGSLPQVLPSPLGVLSGTSRPP--------TPTLSLKPTPPAPVRLSPAPPPGSSSL 1127 Query: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 + PL PP P AA + + + A PTP P + P + L G Sbjct: 1128 LKPLTVPPGYTFPPAAATTTSTTTATATTTAVPA----PTPAPQRLILSPDMQARLPSGE 1183 Query: 573 PPPPSRSPSSTLSGPDLAGHS---------SSATSTPEELRGYDSG-------------P 610 + S AG S + T T ++R G Sbjct: 1184 VVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQRNVVHLVS 1243 Query: 611 EGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG-PGSAD------- 662 GG A +A A + GP P + + P P P +A+ Sbjct: 1244 AGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMV 1303 Query: 663 ---GLCTIYETEGP-ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718 G+ I + P + TP P L P P P +SG A + RL Sbjct: 1304 NNTGVVKIVVRQAPRDGLTPVP-PLAPAPRPPSSGLPAVLNPRPTLT-----PGRLPTPT 1357 Query: 719 LGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGA 754 LG +A + L R LL + S PG A Sbjct: 1358 LGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAA 1393 Score = 62.0 bits (149), Expect = 2e-09 Identities = 174/720 (24%), Positives = 228/720 (31%), Gaps = 178/720 (24%) Query: 93 RAPPAKNTSPGP--VSSPGRASGTTRPGPLGQK----GLRISAEETVARGKATEAPKRSA 146 R P + PG SS G GT R + G R+S AR + A Sbjct: 2355 RLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPV 2414 Query: 147 LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206 +SA R T+ TP SPA R +PRPAP RPRP ++ + Sbjct: 2415 ISAHQTRSTT--TPPRCSPARER----------VPRPAP--RPRPTPASAPAAIPALVPV 2460 Query: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-- 264 + P P + P + S S P SSPA + P A P PAH P Sbjct: 2461 PVSAPVPISAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPP--PAHTPPPAQT 2518 Query: 265 ----PKGLQALRPPQVT-------------PPRKDAAPALGPLSSSPLATPSPSAPPSPS 307 P L PP V P + A AL S LA+ + S S S Sbjct: 2519 CLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESLELASVASSETSSLS 2578 Query: 308 APPSLQTLP-SPPATPPSQATTSL--GSPTLQATHSFLPS-----PPLSPLATPPPQAPP 359 P LP + P S+ SL +P+L +P+ P S T P Sbjct: 2579 LVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPE 2638 Query: 360 ALALP-------PLQAPPSPPASPPLS-PLA--------------TPSPQAPNALAVHLL 397 LP L+ PPS + PL PL T SP+ P L + Sbjct: 2639 GEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEV 2698 Query: 398 QAPF---SPPPSPPVQAPFSP------------------PASPP---------------- 420 AP S SP +P P P PP Sbjct: 2699 AAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTVV 2758 Query: 421 -----------------------VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 457 SA+P S + S++ P P P S S Sbjct: 2759 EEKELVRRRRQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLP 2818 Query: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 PPQ P +A ++L +P L P G+ P Sbjct: 2819 TPPQ-QPFIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPP------------- 2864 Query: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT-SVSGPRLTLALAPGPP--- 573 ++P + + P S T A P PGP+T V+ P L L PGP Sbjct: 2865 -KKNRSPADAGRGVDEAPSSTLKGKTNGA---DPVPGPETLIVADPVLEPQLIPGPQPLG 2920 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS---PPPDAELAACHPA 630 P P P+ LS + + + G S G + S PPP HP+ Sbjct: 2921 PQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPP-------HPS 2973 Query: 631 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTI-YETEGPESATPAPGALDPGPSP 689 + P PPL L P AT A+ + T+ T P+ P P P P Sbjct: 2974 PLT--PLPPL---------LVCPTAT---VANTVTTVTISTSPPKRKRGRPPKNPPSPRP 3019 >gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] Length = 1003 Score = 135 bits (339), Expect = 2e-31 Identities = 225/779 (28%), Positives = 267/779 (34%), Gaps = 150/779 (19%) Query: 17 PAARAPGLLTPRPP-----GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIP 71 P+AR P + P P GS P PP A L G + LA+ GG++ P Sbjct: 143 PSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPVPS-GGSSSP 201 Query: 72 ESAPRAGPTRTSRPPASGRGERA--------------------PPAKNTSPGPVSSPG-- 109 PR + PP A PPA + S P S P Sbjct: 202 RFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLF 261 Query: 110 RASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL--------SAGARRDTSGPTPG 161 S P PL S G A++ P SA G G PG Sbjct: 262 HCSDALTPPPLPP-----SNNLPAHPGPASQPPVSSATMHLPLVLGPLGGAPTVEG--PG 314 Query: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221 P + AA P P PS PR SAS S+ PS RRP Sbjct: 315 APPFLASSLLSAAAKAQHPPLPPPSTL---QGRRPRAQAPSASHSSSLRPSQRRPRRP-- 369 Query: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARG---TPRAPAHPSQP-KPKGLQALRPPQVT 277 P L P +P RS P A P + PSQP P L L P Sbjct: 370 ------PTVFRLLEGRGP-QTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLSLLGLPTPG 422 Query: 278 PPRKDAAPAL--------GPLSSSPLATPSPSAPPSPSAP----PSLQTLPSPPATPPSQ 325 P D + L P + S + P P P PS P SL ++P PA P + Sbjct: 423 PSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPGAPAPPAAS 482 Query: 326 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPS 385 + SP LQ+ PS L A PA LPPL + P P LA Sbjct: 483 KAPVVPSPVLQS-----PSEGLG------MGAGPACPLPPLAGGEAFPFPSPEQGLALSG 531 Query: 386 PQAPNALAVHLLQAPFS---PPPSPPVQAPF-----SPPASPPVSPSATPPSQAPPSLAA 437 P L L P S PPPSP + PP P PP P LA Sbjct: 532 AGFPGMLGA--LPLPLSLGQPPPSPLLNHSLFGVLTGGGGQPPPEPLLPPPGGPGPPLA- 588 Query: 438 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPA---LATPPLQAL-- 492 P P P + ++ PP PP L PPP APP+ + PL AL Sbjct: 589 ------PGEPEGPSLLVASLLPP--------PPSDLL-PPPSAPPSNLLASFLPLLALGP 633 Query: 493 -------PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA---PLLQV---PPS-- 537 + A P PFS L SPL PP APP L A LL PPS Sbjct: 634 TAGDGEGSAEGAGGPSGEPFSGLGDL--SPLLFPPLSAPPTLIALNSALLAATLDPPSGT 691 Query: 538 PPASPTLQAPR-RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS---GPDLAGHS 593 PP L AP+ PPT T+ + P A + G P S P LS G L G Sbjct: 692 PPQPCVLSAPQPGPPTSSVTTATTDPG---ASSLGKAPSNSGRPPQLLSPLLGASLLGDL 748 Query: 594 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWP 653 SS TS+P L P G S +L G PPL+ +P A L Sbjct: 749 SSLTSSPGALPSLLQPP--GPLLSGQLGLQLLP------GGGAPPPLSEASSPLACLLQS 800 Query: 654 PATGPGSADGLCTIYETEG----PESATPAPGAL-DPGPSPGTSGGKAAAGAGAGASSR 707 P + C E+ PE A P AL P SP + G G+G R Sbjct: 801 LQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSGKRGR 859 Score = 98.6 bits (244), Expect = 2e-20 Identities = 141/483 (29%), Positives = 179/483 (37%), Gaps = 84/483 (17%) Query: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPPPQAPPALALPPLQAPPSPP 373 P A+P T S G P+ + P+ PL+ P + PP + A P L P Sbjct: 126 PGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPTLAGPGG-- 183 Query: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-----ATPP 428 PP LA P P ++ F P + P AP PPA +PS A Sbjct: 184 LFPP--RLADPVPSGGSS------SPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRS 235 Query: 429 SQAPPSLAAPPL-QVPPSPPASPPM---SPSATPPPQAPP-PLAAPPLQLAKPPPQAPPA 483 S P L +PP SPP+ PP+ S + TPPP P L A P ++PP + A Sbjct: 236 SLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLPAHPGPASQPPVSS--A 293 Query: 484 LATPPLQALP---SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL---AAPLLQVPPS 537 PL P +P PG PF S+ L + A PP PP P Q P + Sbjct: 294 TMHLPLVLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLPPPSTLQGRRPRAQAPSA 353 Query: 538 PPAS---PTLQAPRRPPT-------PGPDTSVSGPRLTLALAPGPPPPPSRSPS------ 581 +S P+ + PRRPPT GP T PR + AP P P P P Sbjct: 354 SHSSSLRPSQRRPRRPPTVFRLLEGRGPQT----PRRSRPRAPAPVPQPFSLPEPSQPIL 409 Query: 582 -STLSGPDLAGHSSSATSTPEELRGYDS----GPEGGAAASPPPDAELAACHPAAWS--- 633 S LS L S + L G D+ P + + P P + P S Sbjct: 410 PSVLSLLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSL 469 Query: 634 ----RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689 PAPP A + AP P P + G G GP P + P P Sbjct: 470 SSVPGAPAPPAASK-APVVPSPVLQSPSEGLGMG-------AGPACPLPPLAGGEAFPFP 521 Query: 690 GTSGGKAAAGAGAGASSRSPKQARLGELPLG-ALQASVVQHLLSRTLLLAAAEGAAGGSG 748 G A +GAG LG LPL +L LL+ +L G G G Sbjct: 522 SPEQGLALSGAGF--------PGMLGALPLPLSLGQPPPSPLLNHSLF-----GVLTGGG 568 Query: 749 GGP 751 G P Sbjct: 569 GQP 571 Score = 44.3 bits (103), Expect = 5e-04 Identities = 70/271 (25%), Positives = 94/271 (34%), Gaps = 61/271 (22%) Query: 21 APGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG----GATIPESAPR 76 +PG L P +PP P+ L + G PL+E + + IP P Sbjct: 754 SPGAL----PSLLQPPGPLLSGQLGLQLLPGGGAPPPLSEASSPLACLLQSLQIPPEQPE 809 Query: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSP---------GRASGTTRPGPLGQKGLR- 126 A P ++ E A P + P SP GR SG + G G GLR Sbjct: 810 APCLPPESPASALEPEPARPPLSALAPPHGSPDPPVPELLTGRGSG--KRGRRGGGGLRG 867 Query: 127 ISAEETVARGK---ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL--- 180 I+ E ARG+ + P R AL G R +G +P + E G Sbjct: 868 INGEARPARGRKPGSRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPK 927 Query: 181 --PRPAP--------------SARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG 224 P P P S R R P ++ +S+ + T EPSP AR Sbjct: 928 DPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSNSSRQDITLEPSPTAR-------- 979 Query: 225 LQRPASRSLSSSATPLSSPARSGPSARGTPR 255 +A PL AR G A+ R Sbjct: 980 -----------AAVPLPPRARPGRPAKNKRR 999 Score = 30.8 bits (68), Expect = 5.3 Identities = 38/149 (25%), Positives = 50/149 (33%), Gaps = 12/149 (8%) Query: 568 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD---SGPEGGAAASPPPDAEL 624 LAP P P+S L H A + R + S G ASP + Sbjct: 79 LAPVTPGGAGVGPASEEDMTKLCNHRRKAVAMATLYRSMETTCSHSSPGEGASPQMFHTV 138 Query: 625 AACHPAAWSRGPAPPLA-FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 + P+A PP G PG+ P PP+ GP P P Sbjct: 139 SPGPPSARPPCRVPPTTPLNGGPGSLPPEPPSVSQAFPT-------LAGPGGLFP-PRLA 190 Query: 684 DPGPSPGTSGGKAAAGAGAGASSRSPKQA 712 DP PS G+S + A + + P A Sbjct: 191 DPVPSGGSSSPRFLPRGNAPSPAPPPPPA 219 >gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] Length = 1682 Score = 134 bits (337), Expect = 3e-31 Identities = 198/726 (27%), Positives = 249/726 (34%), Gaps = 132/726 (18%) Query: 22 PGLLTPRPPGSPRPPPPVTPAALR-------------VLGAAGAVGRKPLAERAGGIGGA 68 P L P PP P PPPP+ A + G A RK A Sbjct: 248 PPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRH 307 Query: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 ++P P P T+ PP APP P S G T PG LR Sbjct: 308 SLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATRPPG----SDLR-- 361 Query: 129 AEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPS 186 E V R + + +A +A S P PGT + + + S G P P Sbjct: 362 -ESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGI- 419 Query: 187 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATP-LSSPAR 245 P + + S H PS + R+P G + +ATP LS P Sbjct: 420 ----PGADHYQTPALEVSHHGRLGPSAHSSRKPFLG-----------APAATPHLSLPP- 463 Query: 246 SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305 GPS+ P P P P L+ P R+D L L P P+ PP Sbjct: 464 -GPSSPPPPPCPRLLRPPPPPAW--LKGPACRAAREDGE-ILEELFFGTEGPPRPAPPPL 519 Query: 306 PS-----APP----SLQTLPS-PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355 P PP S+ T S P TPP+ T+S S + +HS S P P++ PPP Sbjct: 520 PHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNS--GSHS---SSPAGPVSFPPP 574 Query: 356 QAPPALA--LPPLQAPPSP---PASPPLSPLATPSPQAPNALAVHLLQAPFSPP--PSPP 408 P LA + PL PPSP P PPL PL P AP + F P P P Sbjct: 575 ---PYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPR 631 Query: 409 VQAPFSPPASP--PVSPSATPPSQAPPSLAAPPLQVP---PSPPASPPMSPSATPPPQ-- 461 V P +P P P P + P PP + P + P PP P+ P + Sbjct: 632 VSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPT--PLEDQFEEPAEFK 689 Query: 462 -APPPLAAPPLQL----AKPPPQAPPALATPPLQALPSPPASFPGQAPF----SPSASLP 512 P LA L K Q P L P AS Q+PF +P+ + P Sbjct: 690 ILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASL--QSPFPTDTAPTTTAP 747 Query: 513 MSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGP 572 + T A + P P P + PP P P P Sbjct: 748 AVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQ-------------PPP 794 Query: 573 PPPPS-----RSPSSTLSGPDLA----GHSSSATSTPEELRGYDSGPEGGAAASPPPDAE 623 PPPPS +S +S L G G + S P Y GP GA A PP A Sbjct: 795 PPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA- 853 Query: 624 LAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL 683 AP A G+P P ++ S G E E P PG + Sbjct: 854 -------------AP-----SAQGSPQPSASSSSQFSTSGGPWARERRAGEE--PVPGPM 893 Query: 684 DPGPSP 689 P P Sbjct: 894 TPTQPP 899 Score = 107 bits (266), Expect = 6e-23 Identities = 176/681 (25%), Positives = 232/681 (34%), Gaps = 131/681 (19%) Query: 137 KATEAPKRSALSAGARRDTSGPTPGTPSPAMAR--RSRAAGTEVGLPRPA----PSARPR 190 +A E P + A SG +P R S G GLP P P P Sbjct: 199 RAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPP 258 Query: 191 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGG-------GLQRPASRSLSSSATPLSSP 243 PP P ++++ T+P + A G +R R P +P Sbjct: 259 PPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPHPYPYPAP 318 Query: 244 ARSG--PSARGTPRAPAHPSQPKPKG------LQALRPPQVTPPRKDAAPALGPLSSSPL 295 A + P R P AP P P+P G L A RPP + S SP Sbjct: 319 AYTAHPPGHRLVPAAPPGPG-PRPPGAESHGCLPATRPPGSDLRESRVQRSRMDSSVSPA 377 Query: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG--------------SPTLQATHSF 341 AT + P +PS PP L + ++ S T G +P L+ +H Sbjct: 378 AT-TACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHG 436 Query: 342 LPSPPLSPLATP---PPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA----PNALAV 394 P P P A P L+LPP + P PP P L L P P A P A Sbjct: 437 RLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRL--LRPPPPPAWLKGPACRAA 494 Query: 395 ----HLLQAPF---------SPPPSPPVQAPFSPPAS-----------PPVSPSATPPSQ 430 +L+ F +PPP P + PPAS PP P+ T S Sbjct: 495 REDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSS 554 Query: 431 -----APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQLAKPPPQAPPA 483 + S A P+ PP P + + P PP A P P PL LA PP Sbjct: 555 NSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPP------ 608 Query: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 PP + SF P S P +P P P P+ AP VPP P Sbjct: 609 --APPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP-QPVPPGVGELPA 665 Query: 544 LQAPRR---PPTPGPDTSVSGPRLTLALAPG-------------------------PPPP 575 + PR PPTP D P L G P P Sbjct: 666 -RGPRLFDFPPTPLED-QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQP 723 Query: 576 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 635 P + P ++L P ++ T+ P + A+ + + P Sbjct: 724 PLKEPFASLQSP-FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALP------ 776 Query: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYET-EGPE---SATPAPGALDPGPSPGT 691 P PPLA P P P PP P A L ++ EG + T A + PGP P T Sbjct: 777 PPPPLAKFPPPSQPQP-PPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT 835 Query: 692 SGGKAAAGAGAGASSRSPKQA 712 + + G +GA++ P A Sbjct: 836 ---QYSPGPPSGATALPPTSA 853 Score = 89.7 bits (221), Expect = 1e-17 Identities = 187/707 (26%), Positives = 233/707 (32%), Gaps = 102/707 (14%) Query: 11 GAAARTP-AARAPGLLTPRPPGSP---RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66 GA A TP + PG +P PP P RPPPP PA L K A RA Sbjct: 451 GAPAATPHLSLPPGPSSPPPPPCPRLLRPPPP--PAWL-----------KGPACRAARED 497 Query: 67 GATIPE-SAPRAGPTRTSRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124 G + E GP R + PP R G PPA S G S + T P P Sbjct: 498 GEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDS---HTPPTPPTPTTSSS 554 Query: 125 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184 S + + P L+ + P P PSPA + V L Sbjct: 555 NSNSGSHSSSPAGPVSFPPPPYLAR-----SIDPLPRPPSPAQNPQDPPL---VPLTLAL 606 Query: 185 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL---- 240 P P PP+ + + S + P + + P G G P LS + P+ Sbjct: 607 P---PAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPG---PPPGPLSKAPQPVPPGV 660 Query: 241 -SSPARSGPSARGTPRAP-----AHPSQPK--PKGL---QALRPPQVTPPRKDAAPALGP 289 PAR GP P P P++ K P GL + + + G Sbjct: 661 GELPAR-GPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGV 719 Query: 290 LSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSP 349 PL P S +P T P+ A + TT+ + T AT P P Sbjct: 720 APQPPLKEPFASL----QSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKP---P 772 Query: 350 LATPPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406 A PPP PP PP Q PP PP SP + S A S P Sbjct: 773 PALPPP--PPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPG 830 Query: 407 PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 466 P +SP PP +A PP+ AAP Q P P AS S + P A Sbjct: 831 PLPTTQYSP--GPPSGATALPPTS-----AAPSAQGSPQPSASSSSQFSTSGGPWARERR 883 Query: 467 AA-PPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-----FSPSASLPMSPLAT-- 518 A P+ P Q PP L+ PP ++ SA+ P P+ T Sbjct: 884 AGEEPVPGPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAE 943 Query: 519 ----------PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLAL 568 PP QA Q R SV G R Sbjct: 944 PADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSV-GRRPREGR 1002 Query: 569 APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPE-GGAAASPPPDAELAA 626 A P L DL EE++G + S P+ GGA+ + PP A Sbjct: 1003 AKAKAKVPKEKSRRVLGNLDLQS---------EEIQGREKSRPDLGGASKAKPPTAPAPP 1053 Query: 627 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGP 673 PA S P PP A A P G AD L +EGP Sbjct: 1054 SAPAP-SAQPTPPSASVPGKKAREEAPGPPGVSRADMLKLRSLSEGP 1099 Score = 88.2 bits (217), Expect = 3e-17 Identities = 133/528 (25%), Positives = 163/528 (30%), Gaps = 99/528 (18%) Query: 245 RSGPSARGTPRAPAHPSQPK-----PKGLQALRPP----QVTPPRKDAAPALGPLSSSPL 295 R GP + P P P G + L P + + P PL PL Sbjct: 192 RGGPPVKRAAEPPVVQPVPPAALSGPSGEEGLSPGGKRRRGCNSEQTGLPPGLPLPPPPL 251 Query: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS-----------PTLQATHSFLPS 344 P P PP P P L T P T P +T G P Q LP Sbjct: 252 PPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQRHSLPH 311 Query: 345 PPLSPLATPPPQA-PPALALPPLQAPPSPPASPP------LSPLATP------------- 384 P P P A PP L P APP P PP P P Sbjct: 312 P--YPYPAPAYTAHPPGHRLVP-AAPPGPGPRPPGAESHGCLPATRPPGSDLRESRVQRS 368 Query: 385 ---SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS---LAAP 438 S +P A + AP PP P S +S P+ P P Sbjct: 369 RMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADHYQTP 428 Query: 439 PLQVPPSPPASPPMSPSATP---PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495 L+V P S P P A P L+ PP + PPP P L PP A Sbjct: 429 ALEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKG 488 Query: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 555 PA + L P P PP+ PP+ S Q PPT Sbjct: 489 PACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPT--- 545 Query: 556 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 615 PP P+ S S++ SG HSSS G Sbjct: 546 -----------------PPTPTTSSSNSNSG----SHSSS---------------PAGPV 569 Query: 616 ASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPL-----PWPPATGPGSADGLCTIYET 670 + PPP + P R P+P + P PL P PP++ + G E+ Sbjct: 570 SFPPPPYLARSIDPL--PRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPES 627 Query: 671 EGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELP 718 P + P + PGP PG KA G + RL + P Sbjct: 628 PRPRVSFPKTPEVGPGPPPGPL-SKAPQPVPPGVGELPARGPRLFDFP 674 Score = 53.5 bits (127), Expect = 8e-07 Identities = 129/559 (23%), Positives = 179/559 (32%), Gaps = 105/559 (18%) Query: 27 PRPPGSPRPP--PPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84 PRPP + P PP+ P L + A P S+ + + R Sbjct: 585 PRPPSPAQNPQDPPLVPLTLALPPA---------------------PPSSCHQNTSGSFR 623 Query: 85 PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG-KATEAPK 143 P S R + P K GP PG S +P P G E ARG + + P Sbjct: 624 RPESPRPRVSFP-KTPEVGPGPPPGPLSKAPQPVPPG-------VGELPARGPRLFDFPP 675 Query: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203 P + M + E + P+PP + P S+ S Sbjct: 676 TPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSP 735 Query: 204 --SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS 261 ++ + T +PA + A++ P P P A+ P + P Sbjct: 736 FPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPP--PLAKFPPPSQPQPP 793 Query: 262 QPKP-------KGLQALRPPQVTPPRKDAAPAL---GPLSSSPLATPSPS---APPSPSA 308 P P K L ++ Q R A GPL ++ + PS A P SA Sbjct: 794 PPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSA 853 Query: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP-PLSPLATPPPQA-PPAL----- 361 PS Q P P A+ SQ +TS G + P P P++P PPP + PPA Sbjct: 854 APSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESEV 913 Query: 362 ------ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415 A L A+ P P+ T P ++ LL PP QA Sbjct: 914 LEEISRACETLVERVGRSATDPADPVDTAEPA--DSGTERLL---------PPAQAKEEA 962 Query: 416 PASPPVSPSATPPSQ------------APPSLAAPPLQVPPSPPASPPMSPSA------- 456 VS S + S+ P + A P S Sbjct: 963 GGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLD 1022 Query: 457 -----------TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPA--SFPGQA 503 + P A PP A P AP A TPP ++P A PG Sbjct: 1023 LQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPP 1082 Query: 504 PFSPSASLPMSPLATPPPQ 522 S + L + L+ PP+ Sbjct: 1083 GVSRADMLKLRSLSEGPPK 1101 >gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] Length = 1012 Score = 134 bits (337), Expect = 3e-31 Identities = 181/640 (28%), Positives = 230/640 (35%), Gaps = 140/640 (21%) Query: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115 KP+ E G+ G + G T R SGR ++ P + + P++ R+SG Sbjct: 3 KPVKEEDDGLSGKHSMRTRRSRGSMSTLR---SGR-KKQPASPDGRTSPINEDIRSSGRN 58 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPAMARRSR 172 P SA T + E K+SA + + S P + Sbjct: 59 SP----------SAASTSSNDSKAETVKKSAKKV--KEEASSPLKSNKRQREKVASDTEE 106 Query: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH-----------------STTEPSPAA 215 A T + +RP P+EG +S S S + S + PSP Sbjct: 107 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 166 Query: 216 RRRPSAGGGLQR-----PASRSLSSSATPLSSPARSG----PSARGTPRAPAHPSQPKPK 266 S Q+ P + + TP S A G P+ TP A A P Q P Sbjct: 167 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 226 Query: 267 GLQALRPPQV-TPP----RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL------ 315 QA PQ T P APAL P PSP PP PS P LQ L Sbjct: 227 ASQAPNQPQAPTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSAGQ 281 Query: 316 PSPP--ATPPSQATTSLGSPTLQATHSFL-PSPPL------------SPLATPPPQA--- 357 PS P A PP G +LQA P PP +PL T P A Sbjct: 282 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 341 Query: 358 -----------------------PPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393 PPA LA+P ++ PP+ P P L P+PQA Sbjct: 342 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI-PQL-----PAPQAHKHPP 395 Query: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASP 450 +PFS + P PPA P+S +T PPS PP L P P PS PA P Sbjct: 396 HLSGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 450 Query: 451 P-MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 P ++ S P PPP + PP L + PQ P A Q PF P Sbjct: 451 PGLTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGG 489 Query: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569 P++P P PP Q P S A+ P P + L A Sbjct: 490 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 549 Query: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608 P PPPP RSPS + D H+S + + L RGY+S Sbjct: 550 PESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 589 Score = 124 bits (312), Expect = 3e-28 Identities = 157/559 (28%), Positives = 204/559 (36%), Gaps = 75/559 (13%) Query: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 RRSR + + + R A P T + + S+ +S + S ++ S +++ Sbjct: 21 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 78 Query: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR---KDAAP 285 A + +++PL S R S K K + RP + D+ Sbjct: 79 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 138 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345 SS P + SPS P S Q S + Q P LQA P+P Sbjct: 139 VNDEGSSDPKDIDQDNRSTSPSIP-SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 197 Query: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA--VHLLQAPFSP 403 +P TP P P A PP P + A PQAP A H+ QAP Sbjct: 198 SSAPPGTPQLPTPG----PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 253 Query: 404 PPSPPV-QAPFSPPASPPVSP---SATPPSQAPPSLAAPPL--QVPPSP---PASPPMSP 454 P PP P P PP+ P SA PS PS A PPL Q PP P A P + Sbjct: 254 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA--PSHAQPPLHGQGPPGPHSLQAGPLLQH 311 Query: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPM 513 P P PP A+ + P PA A P LP+ ++ Q P LP Sbjct: 312 PGPPQPFGLPPQASQ----GQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-PREQPLPP 366 Query: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 +PLA P + PP P L P QA + PP +SGP ++ P Sbjct: 367 APLAMPHIKPPPTTPIPQLPAP---------QAHKHPP------HLSGPS-PFSMNANLP 410 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------AC 627 PPP+ P S+LS H SA P +L S P + A PP + A Sbjct: 411 PPPALKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPAS 465 Query: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687 HP AP F P P PP T P P ++TP G Sbjct: 466 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG------ 507 Query: 688 SPGTSGGKAAAGAGAGASS 706 PGTS +GA A S Sbjct: 508 -PGTSAQPPCSGAAASGGS 525 Score = 104 bits (260), Expect = 3e-22 Identities = 135/520 (25%), Positives = 191/520 (36%), Gaps = 115/520 (22%) Query: 68 ATIPESAPRAGPTRT-----SRP--PASGRGERAPPAK-----NTSPGPVSSPGRASGTT 115 A+ E A R +T SRP P+ G GE + ++ P + R++ + Sbjct: 101 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 160 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175 P P + S ++ A+ + +A + AL A PT TP+P+ A G Sbjct: 161 IPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----PPG 203 Query: 176 T-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS---- 230 T ++ P P PSA PP P S + + T P P + + QRP S Sbjct: 204 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 263 Query: 231 ---------RSLSSSATPLSSPARSGPSARGT-PRAP---------AHPSQPKPKGLQAL 271 + L+ SA S+P+ + P G P P HP P+P GL Sbjct: 264 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL--- 320 Query: 272 RPPQVTPPRKD--AAPALG--------PLSSSPLATPSPSA----PPSPSA-----PPSL 312 PPQ + + +PA P S S L + P PP+P A PP Sbjct: 321 -PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 379 Query: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQAPPS 371 +P PA + L P+ + ++ LP PP L PL++ PP+ PPLQ P Sbjct: 380 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 439 Query: 372 P---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATP 427 P+SP P T S P A H P PP Q PF P PP++P P Sbjct: 440 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP 499 Query: 428 PSQAPP-------------------------SLAAPPLQVP---------PSPPASPPMS 453 + PP S P +Q+ P P PP S Sbjct: 500 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 559 Query: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 PS P P A+ + K + + A L +P Sbjct: 560 PSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 599 Score = 93.2 bits (230), Expect = 9e-19 Identities = 127/444 (28%), Positives = 163/444 (36%), Gaps = 71/444 (15%) Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 A+ PA +AP +TP PPG+P+ P P TP+A V P A +A Sbjct: 182 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-----SPTASQAPN---- 232 Query: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 AP A T A + PP+ + P P P T G GQ Sbjct: 233 --QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT---GSAGQPSAPSH 287 Query: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSA 187 A+ + G+ P +L AG GP P A + +A GT Sbjct: 288 AQPPL-HGQGPPGP--HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS---------- 334 Query: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247 P P S+ + S + R +P PA ++ P ++P Sbjct: 335 ---PAAAYPHTSLQLPASQSALQSQQPPREQPLP------PAPLAMPHIKPPPTTPIPQL 385 Query: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307 P+ + + P H S P P + A PP PAL PLSS P + PP Sbjct: 386 PAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKPLSSLSTHHPPSAHPPPLQ 435 Query: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPP 365 P Q LPS PA PP T S P A+H P L +A PP Q P PP Sbjct: 436 LMPQSQPLPSSPAQPPG-LTQSQNLPPPPASH---PPTGLHQVAPQPPFAQHPFVPGGPP 491 Query: 366 LQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ----------APF 413 PP+ P ++PP P + P A A A S P P VQ P Sbjct: 492 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 551 Query: 414 SPPASPPVSPSATPPSQAPPSLAA 437 SPP PP SPS P PS A+ Sbjct: 552 SPP-PPPRSPSPEPTVVDTPSHAS 574 Score = 43.9 bits (102), Expect = 6e-04 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%) Query: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 551 PS P+ ++ SA M P QAP V AP +PP +P L P Sbjct: 159 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 208 Query: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611 TPGP S + A+ P P S++P+ + H+ + P+ Sbjct: 209 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 255 Query: 612 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 666 + PPP HP+ P PPL G P AP PP G G Sbjct: 256 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 298 Query: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 726 GP S P PGP P G P QA G+ PLG A+ Sbjct: 299 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 338 Query: 727 VQHLLSRTLLLAAAEGA 743 H +L L A++ A Sbjct: 339 YPH---TSLQLPASQSA 352 Score = 40.4 bits (93), Expect = 0.007 Identities = 144/644 (22%), Positives = 201/644 (31%), Gaps = 86/644 (13%) Query: 25 LTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83 L P P P PPP TP + L A A P + G + P S P + Sbjct: 364 LPPAPLAMPHIKPPPTTP--IPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 414 Query: 84 RPPASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 P S PP+ + P P S P +S PG + L G Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474 Query: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200 AP+ A GP P TP + + AG P +PP G S Sbjct: 475 APQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAG---------PGTSAQPPCSGAAASG 523 Query: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLSSPARSGPSARGTPR 255 S + S+ P P + + A + P S RS S T + +P+ + SAR Sbjct: 524 GSIAGGSSC-PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 582 Query: 256 APAHPSQPKPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313 + L L ++ R++A + A + Sbjct: 583 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK-AKREAEQKAREEREREKEKEKERERE 641 Query: 314 TLPSPPATPPSQATTS-----LGSPTLQATHSFLPS---PPLSPLATPPPQAPPALALPP 365 A ++A++S L P L PS PP + A PP P AL Sbjct: 642 REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 701 Query: 366 LQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 L P P + P P LA H+ ++ P+ + Sbjct: 702 LSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM-PGLYNVDPTIRERELREREIREREI 760 Query: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAA-----PPL 471 + P P ++ P PA+ PM S PP P P A+ PL Sbjct: 761 RERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPL 820 Query: 472 Q---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528 + LA PQ P ++ P A A P A L M + Q + + Sbjct: 821 ERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHS 880 Query: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP- 587 L P Q P P D +GP L P PP P+ L P Sbjct: 881 HLHLH-----QQDPLHQGSAGPVHPLVDPLTAGPHLARF-----PYPPGTLPNPLLGQPP 930 Query: 588 ---DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 ++ H T P +L G A PPP ++A H Sbjct: 931 HEHEMLRHPVFGTPYPRDLPG----------AIPPP---MSAAH 961 >gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 134 bits (337), Expect = 3e-31 Identities = 181/640 (28%), Positives = 230/640 (35%), Gaps = 140/640 (21%) Query: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115 KP+ E G+ G + G T R SGR ++ P + + P++ R+SG Sbjct: 557 KPVKEEDDGLSGKHSMRTRRSRGSMSTLR---SGR-KKQPASPDGRTSPINEDIRSSGRN 612 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPAMARRSR 172 P SA T + E K+SA + + S P + Sbjct: 613 SP----------SAASTSSNDSKAETVKKSAKKV--KEEASSPLKSNKRQREKVASDTEE 660 Query: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH-----------------STTEPSPAA 215 A T + +RP P+EG +S S S + S + PSP Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720 Query: 216 RRRPSAGGGLQR-----PASRSLSSSATPLSSPARSG----PSARGTPRAPAHPSQPKPK 266 S Q+ P + + TP S A G P+ TP A A P Q P Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780 Query: 267 GLQALRPPQV-TPP----RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL------ 315 QA PQ T P APAL P PSP PP PS P LQ L Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSAGQ 835 Query: 316 PSPP--ATPPSQATTSLGSPTLQATHSFL-PSPPL------------SPLATPPPQA--- 357 PS P A PP G +LQA P PP +PL T P A Sbjct: 836 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 895 Query: 358 -----------------------PPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393 PPA LA+P ++ PP+ P P L P+PQA Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI-PQL-----PAPQAHKHPP 949 Query: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASP 450 +PFS + P PPA P+S +T PPS PP L P P PS PA P Sbjct: 950 HLSGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004 Query: 451 P-MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 P ++ S P PPP + PP L + PQ P A Q PF P Sbjct: 1005 PGLTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGG 1043 Query: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569 P++P P PP Q P S A+ P P + L A Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103 Query: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608 P PPPP RSPS + D H+S + + L RGY+S Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143 Score = 124 bits (312), Expect = 3e-28 Identities = 157/559 (28%), Positives = 204/559 (36%), Gaps = 75/559 (13%) Query: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 RRSR + + + R A P T + + S+ +S + S ++ S +++ Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 632 Query: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR---KDAAP 285 A + +++PL S R S K K + RP + D+ Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 692 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345 SS P + SPS P S Q S + Q P LQA P+P Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIP-SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 751 Query: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA--VHLLQAPFSP 403 +P TP P P A PP P + A PQAP A H+ QAP Sbjct: 752 SSAPPGTPQLPTPG----PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807 Query: 404 PPSPPV-QAPFSPPASPPVSP---SATPPSQAPPSLAAPPL--QVPPSP---PASPPMSP 454 P PP P P PP+ P SA PS PS A PPL Q PP P A P + Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA--PSHAQPPLHGQGPPGPHSLQAGPLLQH 865 Query: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPM 513 P P PP A+ + P PA A P LP+ ++ Q P LP Sbjct: 866 PGPPQPFGLPPQASQ----GQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-PREQPLPP 920 Query: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 +PLA P + PP P L P QA + PP +SGP ++ P Sbjct: 921 APLAMPHIKPPPTTPIPQLPAP---------QAHKHPP------HLSGPS-PFSMNANLP 964 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------AC 627 PPP+ P S+LS H SA P +L S P + A PP + A Sbjct: 965 PPPALKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPAS 1019 Query: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687 HP AP F P P PP T P P ++TP G Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG------ 1061 Query: 688 SPGTSGGKAAAGAGAGASS 706 PGTS +GA A S Sbjct: 1062 -PGTSAQPPCSGAAASGGS 1079 Score = 104 bits (260), Expect = 3e-22 Identities = 135/520 (25%), Positives = 191/520 (36%), Gaps = 115/520 (22%) Query: 68 ATIPESAPRAGPTRT-----SRP--PASGRGERAPPAK-----NTSPGPVSSPGRASGTT 115 A+ E A R +T SRP P+ G GE + ++ P + R++ + Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 714 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175 P P + S ++ A+ + +A + AL A PT TP+P+ A G Sbjct: 715 IPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----PPG 757 Query: 176 T-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS---- 230 T ++ P P PSA PP P S + + T P P + + QRP S Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817 Query: 231 ---------RSLSSSATPLSSPARSGPSARGT-PRAP---------AHPSQPKPKGLQAL 271 + L+ SA S+P+ + P G P P HP P+P GL Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL--- 874 Query: 272 RPPQVTPPRKD--AAPALG--------PLSSSPLATPSPSA----PPSPSA-----PPSL 312 PPQ + + +PA P S S L + P PP+P A PP Sbjct: 875 -PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQAPPS 371 +P PA + L P+ + ++ LP PP L PL++ PP+ PPLQ P Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 372 P---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATP 427 P+SP P T S P A H P PP Q PF P PP++P P Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053 Query: 428 PSQAPP-------------------------SLAAPPLQVP---------PSPPASPPMS 453 + PP S P +Q+ P P PP S Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113 Query: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 PS P P A+ + K + + A L +P Sbjct: 1114 PSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 1153 Score = 93.2 bits (230), Expect = 9e-19 Identities = 127/444 (28%), Positives = 163/444 (36%), Gaps = 71/444 (15%) Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 A+ PA +AP +TP PPG+P+ P P TP+A V P A +A Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-----SPTASQAPN---- 786 Query: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 AP A T A + PP+ + P P P T G GQ Sbjct: 787 --QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT---GSAGQPSAPSH 841 Query: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSA 187 A+ + G+ P +L AG GP P A + +A GT Sbjct: 842 AQPPL-HGQGPPGP--HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS---------- 888 Query: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247 P P S+ + S + R +P PA ++ P ++P Sbjct: 889 ---PAAAYPHTSLQLPASQSALQSQQPPREQPLP------PAPLAMPHIKPPPTTPIPQL 939 Query: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307 P+ + + P H S P P + A PP PAL PLSS P + PP Sbjct: 940 PAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKPLSSLSTHHPPSAHPPPLQ 989 Query: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPP 365 P Q LPS PA PP T S P A+H P L +A PP Q P PP Sbjct: 990 LMPQSQPLPSSPAQPPG-LTQSQNLPPPPASH---PPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 366 LQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ----------APF 413 PP+ P ++PP P + P A A A S P P VQ P Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105 Query: 414 SPPASPPVSPSATPPSQAPPSLAA 437 SPP PP SPS P PS A+ Sbjct: 1106 SPP-PPPRSPSPEPTVVDTPSHAS 1128 Score = 43.9 bits (102), Expect = 6e-04 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%) Query: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 551 PS P+ ++ SA M P QAP V AP +PP +P L P Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762 Query: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611 TPGP S + A+ P P S++P+ + H+ + P+ Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809 Query: 612 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 666 + PPP HP+ P PPL G P AP PP G G Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852 Query: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 726 GP S P PGP P G P QA G+ PLG A+ Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892 Query: 727 VQHLLSRTLLLAAAEGA 743 H +L L A++ A Sbjct: 893 YPH---TSLQLPASQSA 906 Score = 40.4 bits (93), Expect = 0.007 Identities = 144/644 (22%), Positives = 201/644 (31%), Gaps = 86/644 (13%) Query: 25 LTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83 L P P P PPP TP + L A A P + G + P S P + Sbjct: 918 LPPAPLAMPHIKPPPTTP--IPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 968 Query: 84 RPPASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 P S PP+ + P P S P +S PG + L G Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028 Query: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200 AP+ A GP P TP + + AG P +PP G S Sbjct: 1029 APQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAG---------PGTSAQPPCSGAAASG 1077 Query: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLSSPARSGPSARGTPR 255 S + S+ P P + + A + P S RS S T + +P+ + SAR Sbjct: 1078 GSIAGGSSC-PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 1136 Query: 256 APAHPSQPKPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313 + L L ++ R++A + A + Sbjct: 1137 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK-AKREAEQKAREEREREKEKEKERERE 1195 Query: 314 TLPSPPATPPSQATTS-----LGSPTLQATHSFLPS---PPLSPLATPPPQAPPALALPP 365 A ++A++S L P L PS PP + A PP P AL Sbjct: 1196 REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 1255 Query: 366 LQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 L P P + P P LA H+ ++ P+ + Sbjct: 1256 LSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM-PGLYNVDPTIRERELREREIREREI 1314 Query: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAA-----PPL 471 + P P ++ P PA+ PM S PP P P A+ PL Sbjct: 1315 RERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPL 1374 Query: 472 Q---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528 + LA PQ P ++ P A A P A L M + Q + + Sbjct: 1375 ERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHS 1434 Query: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP- 587 L P Q P P D +GP L P PP P+ L P Sbjct: 1435 HLHLH-----QQDPLHQGSAGPVHPLVDPLTAGPHLARF-----PYPPGTLPNPLLGQPP 1484 Query: 588 ---DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 ++ H T P +L G A PPP ++A H Sbjct: 1485 HEHEMLRHPVFGTPYPRDLPG----------AIPPP---MSAAH 1515 >gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] Length = 1566 Score = 134 bits (337), Expect = 3e-31 Identities = 181/640 (28%), Positives = 230/640 (35%), Gaps = 140/640 (21%) Query: 56 KPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 115 KP+ E G+ G + G T R SGR ++ P + + P++ R+SG Sbjct: 557 KPVKEEDDGLSGKHSMRTRRSRGSMSTLR---SGR-KKQPASPDGRTSPINEDIRSSGRN 612 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP---SPAMARRSR 172 P SA T + E K+SA + + S P + Sbjct: 613 SP----------SAASTSSNDSKAETVKKSAKKV--KEEASSPLKSNKRQREKVASDTEE 660 Query: 173 AAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH-----------------STTEPSPAA 215 A T + +RP P+EG +S S S + S + PSP Sbjct: 661 ADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQD 720 Query: 216 RRRPSAGGGLQR-----PASRSLSSSATPLSSPARSG----PSARGTPRAPAHPSQPKPK 266 S Q+ P + + TP S A G P+ TP A A P Q P Sbjct: 721 NESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT 780 Query: 267 GLQALRPPQV-TPP----RKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL------ 315 QA PQ T P APAL P PSP PP PS P LQ L Sbjct: 781 ASQAPNQPQAPTAPVPHTHIQQAPAL-----HPQRPPSPHPPPHPSPHPPLQPLTGSAGQ 835 Query: 316 PSPP--ATPPSQATTSLGSPTLQATHSFL-PSPPL------------SPLATPPPQA--- 357 PS P A PP G +LQA P PP +PL T P A Sbjct: 836 PSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPH 895 Query: 358 -----------------------PPA-LALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393 PPA LA+P ++ PP+ P P L P+PQA Sbjct: 896 TSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPI-PQL-----PAPQAHKHPP 949 Query: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPSLAAPPLQVP-PSPPASP 450 +PFS + P PPA P+S +T PPS PP L P P PS PA P Sbjct: 950 HLSGPSPFSMNANLP-----PPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQP 1004 Query: 451 P-MSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 P ++ S P PPP + PP L + PQ P A Q PF P Sbjct: 1005 PGLTQSQNLP---PPPASHPPTGLHQVAPQPPFA------------------QHPFVPGG 1043 Query: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALA 569 P++P P PP Q P S A+ P P + L A Sbjct: 1044 PPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEE 1103 Query: 570 PGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608 P PPPP RSPS + D H+S + + L RGY+S Sbjct: 1104 PESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNS 1143 Score = 124 bits (312), Expect = 3e-28 Identities = 157/559 (28%), Positives = 204/559 (36%), Gaps = 75/559 (13%) Query: 169 RRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 RRSR + + + R A P T + + S+ +S + S ++ S +++ Sbjct: 575 RRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSN--DSKAETVKKS 632 Query: 229 ASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR---KDAAP 285 A + +++PL S R S K K + RP + D+ Sbjct: 633 AKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRS 692 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345 SS P + SPS P S Q S + Q P LQA P+P Sbjct: 693 VNDEGSSDPKDIDQDNRSTSPSIP-SPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP 751 Query: 346 PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA--VHLLQAPFSP 403 +P TP P P A PP P + A PQAP A H+ QAP Sbjct: 752 SSAPPGTPQLPTPG----PTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH 807 Query: 404 PPSPPV-QAPFSPPASPPVSP---SATPPSQAPPSLAAPPL--QVPPSP---PASPPMSP 454 P PP P P PP+ P SA PS PS A PPL Q PP P A P + Sbjct: 808 PQRPPSPHPPPHPSPHPPLQPLTGSAGQPSA--PSHAQPPLHGQGPPGPHSLQAGPLLQH 865 Query: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA-LPSPPASFPGQAPFSPSASLPM 513 P P PP A+ + P PA A P LP+ ++ Q P LP Sbjct: 866 PGPPQPFGLPPQASQ----GQAPLGTSPAAAYPHTSLQLPASQSALQSQQP-PREQPLPP 920 Query: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP 573 +PLA P + PP P L P QA + PP +SGP ++ P Sbjct: 921 APLAMPHIKPPPTTPIPQLPAP---------QAHKHPP------HLSGPS-PFSMNANLP 964 Query: 574 PPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELA------AC 627 PPP+ P S+LS H SA P +L S P + A PP + A Sbjct: 965 PPPALKPLSSLS----THHPPSAHPPPLQLMP-QSQPLPSSPAQPPGLTQSQNLPPPPAS 1019 Query: 628 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 687 HP AP F P P PP T P P ++TP G Sbjct: 1020 HPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTC------------PSTSTPPAG------ 1061 Query: 688 SPGTSGGKAAAGAGAGASS 706 PGTS +GA A S Sbjct: 1062 -PGTSAQPPCSGAAASGGS 1079 Score = 104 bits (260), Expect = 3e-22 Identities = 135/520 (25%), Positives = 191/520 (36%), Gaps = 115/520 (22%) Query: 68 ATIPESAPRAGPTRT-----SRP--PASGRGERAPPAK-----NTSPGPVSSPGRASGTT 115 A+ E A R +T SRP P+ G GE + ++ P + R++ + Sbjct: 655 ASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPS 714 Query: 116 RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAG 175 P P + S ++ A+ + +A + AL A PT TP+P+ A G Sbjct: 715 IPSPQDNE----SDSDSSAQQQMLQA-QPPALQA--------PTGVTPAPSSA----PPG 757 Query: 176 T-EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS---- 230 T ++ P P PSA PP P S + + T P P + + QRP S Sbjct: 758 TPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPP 817 Query: 231 ---------RSLSSSATPLSSPARSGPSARGT-PRAP---------AHPSQPKPKGLQAL 271 + L+ SA S+P+ + P G P P HP P+P GL Sbjct: 818 PHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGL--- 874 Query: 272 RPPQVTPPRKD--AAPALG--------PLSSSPLATPSPSA----PPSPSA-----PPSL 312 PPQ + + +PA P S S L + P PP+P A PP Sbjct: 875 -PPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPT 933 Query: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-LSPLATPPPQAPPALALPPLQAPPS 371 +P PA + L P+ + ++ LP PP L PL++ PP+ PPLQ P Sbjct: 934 TPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ 993 Query: 372 P---PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP-VQAPFSPPASPPVSPSATP 427 P+SP P T S P A H P PP Q PF P PP++P P Sbjct: 994 SQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCP 1053 Query: 428 PSQAPP-------------------------SLAAPPLQVP---------PSPPASPPMS 453 + PP S P +Q+ P P PP S Sbjct: 1054 STSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRS 1113 Query: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 PS P P A+ + K + + A L +P Sbjct: 1114 PSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMP 1153 Score = 93.2 bits (230), Expect = 9e-19 Identities = 127/444 (28%), Positives = 163/444 (36%), Gaps = 71/444 (15%) Query: 14 ARTPAARAPGLLTP----RPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGA 68 A+ PA +AP +TP PPG+P+ P P TP+A V P A +A Sbjct: 736 AQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQG-----SPTASQAPN---- 786 Query: 69 TIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS 128 AP A T A + PP+ + P P P T G GQ Sbjct: 787 --QPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLT---GSAGQPSAPSH 841 Query: 129 AEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGLPRPAPSA 187 A+ + G+ P +L AG GP P A + +A GT Sbjct: 842 AQPPL-HGQGPPGP--HSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTS---------- 888 Query: 188 RPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 247 P P S+ + S + R +P PA ++ P ++P Sbjct: 889 ---PAAAYPHTSLQLPASQSALQSQQPPREQPLP------PAPLAMPHIKPPPTTPIPQL 939 Query: 248 PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS 307 P+ + + P H S P P + A PP PAL PLSS P + PP Sbjct: 940 PAPQ-AHKHPPHLSGPSPFSMNANLPP---------PPALKPLSSLSTHHPPSAHPPPLQ 989 Query: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP--QAPPALALPP 365 P Q LPS PA PP T S P A+H P L +A PP Q P PP Sbjct: 990 LMPQSQPLPSSPAQPPG-LTQSQNLPPPPASH---PPTGLHQVAPQPPFAQHPFVPGGPP 1045 Query: 366 LQAPPSPP--ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQ----------APF 413 PP+ P ++PP P + P A A A S P P VQ P Sbjct: 1046 PITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPE 1105 Query: 414 SPPASPPVSPSATPPSQAPPSLAA 437 SPP PP SPS P PS A+ Sbjct: 1106 SPP-PPPRSPSPEPTVVDTPSHAS 1128 Score = 43.9 bits (102), Expect = 6e-04 Identities = 69/257 (26%), Positives = 90/257 (35%), Gaps = 69/257 (26%) Query: 493 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPP-VLAAPLLQVPPSPPASPTLQAPRRPP 551 PS P+ ++ SA M P QAP V AP +PP +P L P Sbjct: 713 PSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAP----SSAPPGTPQL------P 762 Query: 552 TPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611 TPGP S + A+ P P S++P+ + H+ + P+ Sbjct: 763 TPGPTPSAT------AVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALH-------PQ 809 Query: 612 GGAAASPPPDAELAACHPAAWSRGPAPPL----AFRGAPGAPL-PWPPATGPGSADGLCT 666 + PPP HP+ P PPL G P AP PP G G Sbjct: 810 RPPSPHPPP-------HPS-----PHPPLQPLTGSAGQPSAPSHAQPPLHGQGPP----- 852 Query: 667 IYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASV 726 GP S P PGP P G P QA G+ PLG A+ Sbjct: 853 -----GPHSLQAGPLLQHPGP-PQPFG--------------LPPQASQGQAPLGTSPAAA 892 Query: 727 VQHLLSRTLLLAAAEGA 743 H +L L A++ A Sbjct: 893 YPH---TSLQLPASQSA 906 Score = 40.4 bits (93), Expect = 0.007 Identities = 144/644 (22%), Positives = 201/644 (31%), Gaps = 86/644 (13%) Query: 25 LTPRPPGSPR-PPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTS 83 L P P P PPP TP + L A A P + G + P S P + Sbjct: 918 LPPAPLAMPHIKPPPTTP--IPQLPAPQAHKHPP------HLSGPS-PFSMNANLPPPPA 968 Query: 84 RPPASGRGERAPPAKNTSP---GPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 P S PP+ + P P S P +S PG + L G Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 1028 Query: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200 AP+ A GP P TP + + AG P +PP G S Sbjct: 1029 APQPPF--AQHPFVPGGPPPITPPTCPSTSTPPAG---------PGTSAQPPCSGAAASG 1077 Query: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPAS-----RSLSSSATPLSSPARSGPSARGTPR 255 S + S+ P P + + A + P S RS S T + +P+ + SAR Sbjct: 1078 GSIAGGSSC-PLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKH 1136 Query: 256 APAHPSQPKPKGL--QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313 + L L ++ R++A + A + Sbjct: 1137 LDRGYNSCARTDLYFMPLAGSKLAKKREEAIEK-AKREAEQKAREEREREKEKEKERERE 1195 Query: 314 TLPSPPATPPSQATTS-----LGSPTLQATHSFLPS---PPLSPLATPPPQAPPALALPP 365 A ++A++S L P L PS PP + A PP P AL Sbjct: 1196 REREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRT 1255 Query: 366 LQAPPSPPASPPLS---PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 422 L P P + P P LA H+ ++ P+ + Sbjct: 1256 LSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHM-PGLYNVDPTIRERELREREIREREI 1314 Query: 423 PSATPPSQAPPSLAAPPLQVPPSPPASPPM------SPSATPPPQAPPPLAA-----PPL 471 + P P ++ P PA+ PM S PP P P A+ PL Sbjct: 1315 RERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPL 1374 Query: 472 Q---LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLA 528 + LA PQ P ++ P A A P A L M + Q + + Sbjct: 1375 ERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHS 1434 Query: 529 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP- 587 L P Q P P D +GP L P PP P+ L P Sbjct: 1435 HLHLH-----QQDPLHQGSAGPVHPLVDPLTAGPHLARF-----PYPPGTLPNPLLGQPP 1484 Query: 588 ---DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628 ++ H T P +L G A PPP ++A H Sbjct: 1485 HEHEMLRHPVFGTPYPRDLPG----------AIPPP---MSAAH 1515 >gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] Length = 2217 Score = 132 bits (332), Expect = 1e-30 Identities = 147/510 (28%), Positives = 175/510 (34%), Gaps = 107/510 (20%) Query: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 240 P PA P +EGP S PS A ++P+A GL Sbjct: 645 PSPAQCVCSPPVSEGPVLPQSL--------PSLGAYQQPTAAPGL--------------- 681 Query: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 300 P S P+ P H P L PP P PA PLA P+P Sbjct: 682 --PVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTP 739 Query: 301 SAPPSPSAP-PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359 P AP P + P PP PP A S Q +P PL PLA PPQ PP Sbjct: 740 L--PQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPP 797 Query: 360 ALALPPLQA-------PPS---------PPASPP--------LSPLATPSPQAPNALAVH 395 +PP+ PP+ PP PP L LA P P A AL + Sbjct: 798 IPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQ 857 Query: 396 LLQAPFSPP-----------PSPPVQAPFSPPASP-----------------PVSPSATP 427 ++ P P P+ P P A P PV P+A P Sbjct: 858 AVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFP 917 Query: 428 ---PSQAPPS--------LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 P+ PPS A PP P P PP P P P PP PP P Sbjct: 918 QMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQ-PVLPPQPTLPPQPVLPPQPTRPP 976 Query: 477 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPP 536 P PP PP LP PA P P +P ATP Q +L P Sbjct: 977 QPVLPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAATPGSQ--------ILLGHP 1028 Query: 537 SPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS--TLSGPDLAGHSS 594 +P A A + P P P +V P L L P P + PSS T+S + + Sbjct: 1029 APYAVDV--AAQVPTVPVPPAAVLSPPLPEVLLPAAPELLPQFPSSLATVSASVQSVPTQ 1086 Query: 595 SATSTPEELRGYDSGPEGGAAASPPPDAEL 624 +AT P GP ASP P +L Sbjct: 1087 TATLLPPANPPLPGGP---GIASPCPTVQL 1113 Score = 128 bits (322), Expect = 2e-29 Identities = 158/544 (29%), Positives = 208/544 (38%), Gaps = 76/544 (13%) Query: 210 EPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ 269 +P P P A L P +L +SAT L+S + T + + SQ L Sbjct: 583 QPGPPEPEEPEADQHLLPP---TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVM-LG 638 Query: 270 ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP-PATPPSQATT 328 +L +P + +P + P + PS A P+A P L P PA PP Sbjct: 639 SLADAAPSPAQCVCSPPVSEGPVLPQSLPSLGAYQQPTAAPGLPVGSVPAPACPP----- 693 Query: 329 SLGSPTLQATHSFLP--SPPLSPLAT------PPPQAPPALA----LPPLQAP----PSP 372 SL SF P PP +P+ T PP Q PP LA LP + AP P Sbjct: 694 SLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQ 753 Query: 373 PASPPLSPLATPSPQ--APNAL-AVHLLQAPFS-----PPPSPPVQAPFSPPASP----- 419 P P L P P+ Q AP L + + QAP PP PP+ P PP +P Sbjct: 754 PVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPI--PVVPPITPLAGID 811 Query: 420 ------PVSPSATPPSQAPPSLAAPPLQVP----PSPPASPPMSPSATPPPQAP-PPLAA 468 P P+AT P PP +P + +P P PPASP + A P P PLA Sbjct: 812 GLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAM 871 Query: 469 PPLQLAKPPPQAPPALATPP----LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAP 524 P + P P LA P ++ S A PGQ P P+A M+P PP +P Sbjct: 872 PCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQ-PVYPAAFPQMAPTDVPP--SP 928 Query: 525 PVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTL 584 + PP P P P +P P T P+ L P PP P P L Sbjct: 929 HHTVQNMRATPPQPALPPQPTLPPQPVLPPQPT--LPPQPVLPPQPTRPPQPVLPPQPML 986 Query: 585 SGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWS--------RGP 636 + + PE L+ + PE A A+ P +++ HPA ++ P Sbjct: 987 PPQPVLPPQPALPVRPEPLQPH--LPEQAAPAA-TPGSQILLGHPAPYAVDVAAQVPTVP 1043 Query: 637 APPLAFRG--APGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG 694 PP A P LP P P L T+ + +S L P +P GG Sbjct: 1044 VPPAAVLSPPLPEVLLPAAPELLPQFPSSLATV--SASVQSVPTQTATLLPPANPPLPGG 1101 Query: 695 KAAA 698 A Sbjct: 1102 PGIA 1105 Score = 94.0 bits (232), Expect = 5e-19 Identities = 162/600 (27%), Positives = 216/600 (36%), Gaps = 118/600 (19%) Query: 2 DNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAER 61 D++ + + AA +P PP S P V P +L LGA ++P A Sbjct: 627 DSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGP---VLPQSLPSLGAY----QQPTA-- 677 Query: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKN---TSPGPVSSPGRASGTTRPG 118 A G+ ++P A + PA PP T PG + PG+ +P Sbjct: 678 APGLPVGSVPAPACPPSLQQHFPDPAMSFAPVLPPPSTPMPTGPGQPAPPGQ-----QPP 732 Query: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178 PL Q T P+ A P P P +A S+ Sbjct: 733 PLAQP---------------TPLPQVLAPQPVVPLQ---PVPPHLPPYLAPASQVGAPAQ 774 Query: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR-RPSAGGGLQRPASRSLSSSA 237 P P A +P + P + P P P AG PA L ++ Sbjct: 775 LKPLQMPQAPLQPLAQVPPQM----------PPIPVVPPITPLAGIDGLPPALPDLPTAT 824 Query: 238 TP------LSSPARSGPSARGT--PRAPAHPSQ----PKPKGLQALRPPQVTPPRKDAAP 285 P SPA PS P +PA P Q P P G P + P AP Sbjct: 825 VPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRTIVPN---AP 881 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLG-SP--TLQATHSFL 342 A PL + +A P +A SA L P PA P A T + SP T+Q + Sbjct: 882 ATIPLLA--VAPPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATP 939 Query: 343 PSPPLSPLATPPPQA--PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400 P P L P T PPQ PP LPP P P PP P+ P P P Q Sbjct: 940 PQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPP-QPVLPPQPMLPP-------QPV 991 Query: 401 FSPPPSPPVQA-PFSPPASPPVSPSATPPSQ------APPSL----AAPPLQVPPSPPAS 449 P P+ PV+ P P +P+ATP SQ AP ++ P + VPP+ S Sbjct: 992 LPPQPALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLS 1051 Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT--PPLQALPSPPASFPGQAPFSP 507 PP+ P AAP L PQ P +LAT +Q++P+ A+ Sbjct: 1052 PPLPEVLLP--------AAPELL-----PQFPSSLATVSASVQSVPTQTAT--------- 1089 Query: 508 SASLPMSPLATPPPQAPPVLAA--PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLT 565 + P A PP P +A+ P +Q+ P + P P S G +T Sbjct: 1090 -----LLPPANPPLPGGPGIASPCPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVT 1144 Score = 71.6 bits (174), Expect = 3e-12 Identities = 104/406 (25%), Positives = 141/406 (34%), Gaps = 64/406 (15%) Query: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS----SPLATPSPSAPPSPSAPPS 311 AP P P L +L PP+ + +D+AP LSS S LA+ + PS PP Sbjct: 1323 APEAPESSPPLPLSSL-PPEAS---QDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378 Query: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP-PQAPPAL------ALP 364 P P++PP A G+ +T +P P + P P L + P Sbjct: 1379 APPAPLAPSSPPVTALPQDGAAPATST---MPEPASGTASQAGGPGTPQGLTSELETSQP 1435 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPASPPVSP 423 + +P A PL P AP A + AP P PP P +P S P + Sbjct: 1436 LAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQ 1495 Query: 424 SAT--PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP-QAPPPLAAPPLQLAKPPPQA 480 A P + SLA L PP P PP PSA + PPP K + Sbjct: 1496 PAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDGEGPPPRVGFVDSTIKSLDEK 1555 Query: 481 PPALATPPLQALPSPPASFP---GQAPFS--------PSASLPMSPLATPPPQAPPVLAA 529 L S A P G F+ P + + LA PP P + Sbjct: 1556 LRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGDQPRSEVCGGDLALPP--VPKEAVS 1613 Query: 530 PLLQVP----PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585 +Q+P +PT A T T+ S PR L Sbjct: 1614 GRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGY--------------DRD 1659 Query: 586 GPDLAGHSSSATSTPEELRGY-----------DSGPEGGAAASPPP 620 G +A S S P+++ + D G G ++A PPP Sbjct: 1660 GRQVASDSHVVPSVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPP 1705 Score = 62.8 bits (151), Expect = 1e-09 Identities = 152/617 (24%), Positives = 205/617 (33%), Gaps = 98/617 (15%) Query: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPES 73 A PA AP P P S P A + ++ +++ G + P Sbjct: 1319 AEHPAPEAPESSPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPG 1378 Query: 74 APRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133 AP A +S P + + A PA +T P P S +G GP +GL E + Sbjct: 1379 APPAPLAPSSPPVTALPQDGAAPATSTMPEPASGTASQAG----GPGTPQGLTSELETSQ 1434 Query: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193 + EAP + G P TP+P A A+ LP PAP P T Sbjct: 1435 PLAETHEAP------LAVQPLVVGLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGT 1488 Query: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 253 P + +P+P P+A G + SL++S P SP Sbjct: 1489 PQP----------ALGQPAPLL---PAAVGAV------SLATSQLP--SP---------- 1517 Query: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQ 313 P P P QP AL PP P +G + S+ S L+ Sbjct: 1518 PLGPTVPPQPP----SALESDGEGPP-----PRVGFVDST-----------IKSLDEKLR 1557 Query: 314 TLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA---LALPPLQAPP 370 TL P S A S G+P F L PL P++ LALPP+ Sbjct: 1558 TLLYQEHVPTSSA--SAGTPVEVGDRDF----TLEPLRGDQPRSEVCGGDLALPPVPKEA 1611 Query: 371 SPPASPPLSPLATPSPQAPNALAV--HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 428 PL S AP AV + + SP + S S P Sbjct: 1612 VSGRVQLPQPLVEKSELAPTRGAVMEQGTSSSMTAESSPRSMLGYDRDGRQVASDSHVVP 1671 Query: 429 S--QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALAT 486 S Q P+ P P SA PPP + Q + P AL + Sbjct: 1672 SVPQDVPAFVRPARVEPTDRDGGEAGESSAEPPPSDMGTVGG---QASHPQTLGARALGS 1728 Query: 487 P---PLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543 P P Q S PA G+ FS ++ LA+ P + A P + + +P + Sbjct: 1729 PRKRPEQQDVSSPAKTVGR--FSVVSTQDEWTLAS--PHSLRYSAPPDVYLDEAPSSPDV 1784 Query: 544 LQAPRRPPTPG--------PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595 A RR T P +S SG P PP + S +SG Sbjct: 1785 KLAVRRAQTASSIEVGVGEPVSSDSGDE-----GPRARPPVQKQASLPVSGSVAGDFVKK 1839 Query: 596 ATS-TPEELRGYDSGPE 611 AT+ R GPE Sbjct: 1840 ATAFLQRPSRAGSLGPE 1856 Score = 62.0 bits (149), Expect = 2e-09 Identities = 94/347 (27%), Positives = 113/347 (32%), Gaps = 54/347 (15%) Query: 345 PPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPP 404 P L P +P PP+ P P+ P A HLL PP Sbjct: 548 PALQPKEQQDVGSPDKARGPPVPLQVQVTYHAQAGQPGPPEPEEPEA-DQHLL-----PP 601 Query: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSL----------AAP-PLQVPPSPPASP-PM 452 P + ++ +T S + S AAP P Q SPP S P+ Sbjct: 602 TLPTSATSLASDSTFDSGQGSTVYSDSQSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPV 661 Query: 453 SPSATPPPQA-PPPLAAPPLQLAK-PPPQAPPALATPPLQALPSPPASF-----PGQAPF 505 P + P A P AAP L + P P PP+L Q P P SF P P Sbjct: 662 LPQSLPSLGAYQQPTAAPGLPVGSVPAPACPPSLQ----QHFPDPAMSFAPVLPPPSTPM 717 Query: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR-- 563 P P PPP A P +L P P P P PP P + V P Sbjct: 718 PTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPLQPV--PPHLPPYLAPASQVGAPAQL 775 Query: 564 --LTLALAPGPP---PPPSRSPSSTLSG-PDLAGHSSSATSTPEELRGYDSGPEGGAAAS 617 L + AP P PP P + LAG + P+ P Sbjct: 776 KPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDL-------PTATVPPV 828 Query: 618 PPPD--------AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 PPP LAA P A P + PGAPL P T Sbjct: 829 PPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCRT 875 Score = 53.5 bits (127), Expect = 8e-07 Identities = 103/424 (24%), Positives = 154/424 (36%), Gaps = 54/424 (12%) Query: 11 GAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERA-GGIGGAT 69 G A TPA A P P PPP P+ PL A G + AT Sbjct: 1452 GLAPCTPAPEAASTRDASAPREPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLAT 1511 Query: 70 IPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 129 +P GPT +PP++ ++ GP G T + L +K + Sbjct: 1512 SQLPSPPLGPTVPPQPPSA--------LESDGEGPPPRVGFVDSTIK--SLDEKLRTLLY 1561 Query: 130 EETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189 +E V A+ + + G R T P G RS G ++ LP P P Sbjct: 1562 QEHVPTSSASAG---TPVEVGDRDFTLEPLRGDQP-----RSEVCGGDLALP-PVPKEAV 1612 Query: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249 + P+ V E S A P+ G +++ S S+++ ++P S Sbjct: 1613 SGRVQLPQPLV---------EKSELA---PTRGAVMEQGTSSSMTAESSPRSMLGYDRDG 1660 Query: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309 + + PS P+ +RP +V P +D A G S+ P + + S P Sbjct: 1661 RQVASDSHVVPSVPQDVP-AFVRPARVEPTDRDGGEA-GESSAEPPPSDMGTVGGQASHP 1718 Query: 310 PSL--QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP---QAPPALALP 364 +L + L SP P Q +S S + + LA+P APP + L Sbjct: 1719 QTLGARALGSPRKRPEQQDVSSPAKTV--GRFSVVSTQDEWTLASPHSLRYSAPPDVYLD 1776 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS------PPPSPPVQAPFSPPAS 418 +AP SP LA Q +++ V + + S P PPVQ S P S Sbjct: 1777 --EAPSSPDVK-----LAVRRAQTASSIEVGVGEPVSSDSGDEGPRARPPVQKQASLPVS 1829 Query: 419 PPVS 422 V+ Sbjct: 1830 GSVA 1833 Score = 53.1 bits (126), Expect = 1e-06 Identities = 72/245 (29%), Positives = 95/245 (38%), Gaps = 39/245 (15%) Query: 458 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 517 P P+AP ++PPL L+ PP+A A P L S Q F S L Sbjct: 1322 PAPEAPE--SSPPLPLSSLPPEASQDSA-PYKDQLSSKE-----QPSFLASQQLLSQAGP 1373 Query: 518 TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPS 577 + PP APP APL P SPP + Q P T SG T + A GP P Sbjct: 1374 SNPPGAPP---APL--APSSPPVTALPQDGAAPATSTMPEPASG---TASQAGGPGTPQG 1425 Query: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 637 + S P H + P + G A +P P+A A+ A+ R P Sbjct: 1426 LTSELETSQPLAETHEAPLAVQPLVV--------GLAPCTPAPEA--ASTRDASAPREPL 1475 Query: 638 PPLAFRGAPGAPLPWP----PATGPGSADGLCTIYETE------GPESATPAPGALD--- 684 PP A +P + P P PA +A G ++ ++ GP P AL+ Sbjct: 1476 PPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSALESDG 1535 Query: 685 PGPSP 689 GP P Sbjct: 1536 EGPPP 1540 Score = 46.6 bits (109), Expect = 9e-05 Identities = 69/237 (29%), Positives = 89/237 (37%), Gaps = 46/237 (19%) Query: 476 PPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 P P+AP + +PPL PP + AP+ S P Q L Q Sbjct: 1322 PAPEAPES--SPPLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQL-------LSQAG 1372 Query: 536 PS-PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594 PS PP +P AP P +P P T++ P+ A A P P+ +S GP + Sbjct: 1373 PSNPPGAPP--APLAPSSP-PVTAL--PQDGAAPATSTMPEPASGTASQAGGPGTPQGLT 1427 Query: 595 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 654 S T + L P A P LA C PA A AP PLP PP Sbjct: 1428 SELETSQPLAETHEAP----LAVQPLVVGLAPCTPAP----EAASTRDASAPREPLP-PP 1478 Query: 655 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGG--KAAAGAGAGASSRSP 709 A PE P+P + P P+ G AA GA + A+S+ P Sbjct: 1479 A-----------------PE---PSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLP 1515 Score = 37.4 bits (85), Expect = 0.057 Identities = 32/120 (26%), Positives = 42/120 (35%), Gaps = 9/120 (7%) Query: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALR 272 P P G G PA A P + AR GP R R+ Q +P GL+A Sbjct: 11 PGTLMEPGRGAG---PAGM-----AEPRAKAARPGPQ-RFLRRSVVESDQEEPPGLEAAE 61 Query: 273 PPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGS 332 P PP+ L + L P+ AP +L P P P +G+ Sbjct: 62 APGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGT 121 Score = 36.6 bits (83), Expect = 0.096 Identities = 28/97 (28%), Positives = 41/97 (42%), Gaps = 4/97 (4%) Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 P + + P PQ P PL L L K P P+ + PG AP +P+ Sbjct: 55 PGLEAAEAPGPQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPG-APGAPAD 113 Query: 510 SLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 546 + P P+ T P P+ AA ++ P+P P +A Sbjct: 114 AGP-EPVGTQEPGPDPIAAA--VETAPAPDGGPREEA 147 Score = 36.2 bits (82), Expect = 0.13 Identities = 49/170 (28%), Positives = 61/170 (35%), Gaps = 29/170 (17%) Query: 62 AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 121 AG G A A R GP R R + PP + P P P PL Sbjct: 21 AGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQP--------PQPLQ 72 Query: 122 QKGL------RISAEETVARGKATEAPKRSALSA-----GARRDTSGPTP-GTPSPAMAR 169 ++ L R+ AE ARG+ AP +AL A GA D +GP P GT P Sbjct: 73 RRVLLLCKTRRLIAER--ARGRPA-APAPAALVAQPGAPGAPAD-AGPEPVGTQEPGPDP 128 Query: 170 RSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP 219 + A T PAP PR + + + EP R P Sbjct: 129 IAAAVET-----APAPDGGPREEAAATVRKEDEGAAEAKPEPGRTRRDEP 173 Score = 32.3 bits (72), Expect = 1.8 Identities = 44/166 (26%), Positives = 51/166 (30%), Gaps = 18/166 (10%) Query: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV------SGPRLTLALAPGPPPPPS 577 P L P P+ A P +A R P SV P L A APGP PP Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQP 70 Query: 578 RSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP--PDAELAACHPAAWSRG 635 L + E RG + P A + P P A A ++ Sbjct: 71 LQRRVLLL-------CKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQE 123 Query: 636 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 P P AP P GP E EG A P PG Sbjct: 124 PGPDPIAAAVETAP---APDGGPREEAAATVRKEDEGAAEAKPEPG 166 Score = 32.0 bits (71), Expect = 2.4 Identities = 72/301 (23%), Positives = 104/301 (34%), Gaps = 36/301 (11%) Query: 145 SALSAGARRDTSGPT--PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSS 202 +A G RR TS G + R+ + + G A S+R PP + P ++ Sbjct: 1939 TAPPTGRRRKTSKSKLKAGKLLNPLVRQLKVVASSTG--HLADSSRG-PPAKDPAQASVG 1995 Query: 203 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHP-- 260 + ST A + Q+P S S S+ S A G ARG HP Sbjct: 1996 LTADSTGLSGKAVQT--------QQPCSVRASLSSDICSGLASDGGGARGQGWTVYHPTS 2047 Query: 261 ------SQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSL-- 312 S KP+ P V+ LG SS +T S + P P P+L Sbjct: 2048 ERVTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPALHV 2107 Query: 313 QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSP 372 Q + T L + T + + L P Q L ++A Sbjct: 2108 QAQVNNSNNKKGTFTDDLHKLVDEWTSKTVGAAQLKPTLN---QLKQTQKLQDMEAQAGW 2164 Query: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQA 431 A P A +P+A + P PP P+ P A+P +S P+ P S+ Sbjct: 2165 AA--PGEARAMTAPRAGVGM-------PRLPPAPGPLSTTVIPGAAPTLSVPTPDPESEK 2215 Query: 432 P 432 P Sbjct: 2216 P 2216 Score = 30.4 bits (67), Expect = 6.9 Identities = 39/155 (25%), Positives = 56/155 (36%), Gaps = 30/155 (19%) Query: 102 PGPVSSPGRASG----------TTRPGPLGQKGLRISAEETVARG----KATEAP----- 142 PG + PGR +G RPGP Q+ LR S E+ +A EAP Sbjct: 11 PGTLMEPGRGAGPAGMAEPRAKAARPGP--QRFLRRSVVESDQEEPPGLEAAEAPGPQPP 68 Query: 143 ----KRSALSAGARR---DTSGPTPGTPSPA-MARRSRAAGTEVGL-PRPAPSARPRPPT 193 +R L RR + + P P+PA + + A G P P + P P Sbjct: 69 QPLQRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDP 128 Query: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228 + A + E + A R+ G +P Sbjct: 129 IAAAVETAPAPDGGPREEAAATVRKEDEGAAEAKP 163 >gi|239508790 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 490 Score = 128 bits (321), Expect = 2e-29 Identities = 137/458 (29%), Positives = 184/458 (40%), Gaps = 57/458 (12%) Query: 228 PASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL 287 P L S PL SP S + HP P L + P ++P +P Sbjct: 25 PPHHPLVSLHHPLVSPHFPLVSPHHPLVSLHHPVSPHFP-LVSPHHPLMSPHYSLVSPQY 83 Query: 288 GPLSSS-PLATPSPS--APPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPS 344 P+S PL +P S +P P P L +PSPP+ PS S +PS Sbjct: 84 SPVSPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLL-------------SGVPS 130 Query: 345 PPLSPLATPPPQAPPALALPP--LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402 P S +++PP P L+ P L PSPP+ P P PSP + + + +P S Sbjct: 131 LP-SDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPSPPSDVPSPPSDVPSLLSGVPSPPS 189 Query: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAP--PSLAAPPLQVPPSPPASPPMSPSATPPP 460 PSPP P P P +S +PPS P + +PP VP P P +S +PP Sbjct: 190 DVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPSLSGVPSPPS 249 Query: 461 QAPPPLA---APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP--MSP 515 P L+ +PP ++ PP P L+ P +LPS S P SP + +P +S Sbjct: 250 DVPSLLSGVPSPPSDIS-PPSDVPSLLSDVP--SLPSDVPSLLSGVP-SPPSDVPSLLSD 305 Query: 516 LATPPPQAP-PVLAAPLLQVPPSPPA---SPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 + +PP P P PLL PSPP+ SP P P + V P + L G Sbjct: 306 VPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSG 365 Query: 572 PPPPPSRSPSSTLS------------GPDLAGHSSSATSTPEELRGYDSGPEGGAAASPP 619 P PPS PS +S P S + P L G S P G S P Sbjct: 366 VPSPPSDVPSLLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSG--VPSLP 423 Query: 620 PDAELAACHPAAWSRGPAPPLAFRGAPGAPLP-WPPAT 656 + + P+ S P+P G P+ W P T Sbjct: 424 SGVPILSGVPSLPSGVPSP-------SGVPITLWCPLT 454 Score = 100 bits (248), Expect = 7e-21 Identities = 110/366 (30%), Positives = 143/366 (39%), Gaps = 48/366 (13%) Query: 337 ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP--PLSPLATP-SPQAPNALA 393 +TH + SP PL PP P PL +P P SP PL L P SP P Sbjct: 11 STHYSVVSPHC-PLV--PPHHPLVSLHHPLVSPHFPLVSPHHPLVSLHHPVSPHFPLVSP 67 Query: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 453 H L +P SP +P SP P VSP + S P L +P L PSPP+ P Sbjct: 68 HHPLMSPHYSLVSPQY-SPVSPHC-PLVSPHYSLVSPHRP-LVSPLLSGVPSPPSDVPSL 124 Query: 454 PSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAPFSPSASL 511 S P + P ++ PP P L+ P L +PSPP+ P Sbjct: 125 LSGVP---------SLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPSDVPS---------- 165 Query: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 571 P S + +PP P +L+ + PPS SP P P + V P + L Sbjct: 166 PPSDVPSPPSDVPSLLSG--VPSPPSDVPSPPSDVPSPPSDVPLLSDVPSPPSDVPLLSD 223 Query: 572 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDA--------E 623 P PPS PS P L+G S + P L G S P SPP D Sbjct: 224 VPSPPSDVPSLPSDVPSLSGVPSPPSDVPSLLSGVPSPPSD---ISPPSDVPSLLSDVPS 280 Query: 624 LAACHPAAWSRGPAPPLAFRGAPG--APLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 L + P+ S P+PP P + +P PP+ P + + P S P+P Sbjct: 281 LPSDVPSLLSGVPSPP---SDVPSLLSDVPSPPSDVPSPPSDIPLLSGVPSPPSDVPSPP 337 Query: 682 ALDPGP 687 + P P Sbjct: 338 SDVPSP 343 Score = 99.0 bits (245), Expect = 2e-20 Identities = 112/373 (30%), Positives = 142/373 (38%), Gaps = 72/373 (19%) Query: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSP--PLSPLATP-PPQAPPALALPPLQAPPSP 372 P P PP SL P L + H L SP PL L P P P PL +P Sbjct: 19 PHCPLVPPHHPLVSLHHP-LVSPHFPLVSPHHPLVSLHHPVSPHFPLVSPHHPLMSPHYS 77 Query: 373 PASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPV---------SP 423 SP SP+ SP P + L +P P SP + SPP+ P S Sbjct: 78 LVSPQYSPV---SPHCPLVSPHYSLVSPHRPLVSPLLSGVPSPPSDVPSLLSGVPSLPSD 134 Query: 424 SATPPSQAP------PSLAA----PPLQVPPSPPASPPMSPSATPP-----PQAPPPLAA 468 ++PPS P PSL + PP VP SPP+ P PS P P P + + Sbjct: 135 VSSPPSDVPSLLSDVPSLLSGVPSPPSDVP-SPPSDVPSPPSDVPSLLSGVPSPPSDVPS 193 Query: 469 PPLQLAKPPPQAP-------PALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP 521 PP + PP P P P L +PSPP+ P PS +S + +PP Sbjct: 194 PPSDVPSPPSDVPLLSDVPSPPSDVPLLSDVPSPPSDVPSLPSDVPS----LSGVPSPPS 249 Query: 522 QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL---TLALAPGPPPPPSR 578 P +L+ PSPP+ + PP+ P P L +L G P PPS Sbjct: 250 DVPSLLSG-----VPSPPSDIS------PPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSD 298 Query: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638 PS D+ S S P ++ P SPP D P+ S P+P Sbjct: 299 VPSLL---SDVPSPPSDVPSPPSDI------PLLSGVPSPPSDV------PSPPSDVPSP 343 Query: 639 PLAFRGAPGAPLP 651 P G P P Sbjct: 344 PSDVPLLSGVPSP 356 Score = 90.1 bits (222), Expect = 7e-18 Identities = 106/372 (28%), Positives = 138/372 (37%), Gaps = 55/372 (14%) Query: 180 LPRPAPSARPRPPTEGPR--KSVSSASEHSTTEPSPAARRR---PSAGGGLQRPASRSLS 234 L P S P PP++ P V S ++ PS PS G+ P S + Sbjct: 106 LVSPLLSGVPSPPSDVPSLLSGVPSLPSDVSSPPSDVPSLLSDVPSLLSGVPSPPS-DVP 164 Query: 235 SSATPLSSPARSGPSA-RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S + + SP PS G P P+ P P V P D PL S Sbjct: 165 SPPSDVPSPPSDVPSLLSGVPSPPSDVPSP---------PSDVPSPPSDV-----PLLSD 210 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP------L 347 PSP PS P L +PSPP+ PS P+ + S +PSPP L Sbjct: 211 ---VPSP-----PSDVPLLSDVPSPPSDVPS-------LPSDVPSLSGVPSPPSDVPSLL 255 Query: 348 SPLATPPPQAPPALALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 406 S + +PP P +P L + PS P+ P PSP + + + +P S PS Sbjct: 256 SGVPSPPSDISPPSDVPSLLSDVPSLPSDVPSLLSGVPSPPSDVPSLLSDVPSPPSDVPS 315 Query: 407 PPVQAPFSPPASPPVSPSATPPSQAP-PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465 PP P P S +PPS P P P L PSP + P+ PP P Sbjct: 316 PPSDIPLLSGVPSPPSDVPSPPSDVPSPPSDVPLLSGVPSPLSDVPLLSGVPSPPSDVPS 375 Query: 466 LAAPP-------LQLAKPPPQAPPALATPP---LQALPSPPASFPGQAPFSPSAS-LPMS 514 L P L P P+L + L +PS P+ P P S +P Sbjct: 376 LLMSPHRLLMSHYSLVSPHRLDVPSLLSDVPSLLSGVPSSPSGVPSLPSGVPILSGVPSL 435 Query: 515 PLATPPPQAPPV 526 P P P P+ Sbjct: 436 PSGVPSPSGVPI 447 >gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens] Length = 2161 Score = 126 bits (317), Expect = 7e-29 Identities = 226/877 (25%), Positives = 300/877 (34%), Gaps = 150/877 (17%) Query: 22 PGLLTPRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPT 80 P +P P SP+PPP V P+ + + + P +G + E+ P P Sbjct: 1127 PPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPE 1186 Query: 81 RTSRPPASGRGERAPPAKNT---SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGK 137 T G PA + SP PV +P SG Q G + G Sbjct: 1187 PTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPASPSGPATLDFTSQFGAALVGAARREGGW 1246 Query: 138 ATEAPKRSAL--SAGARRDTSGPTP-GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194 EA +RS L S A + G GT + R + + G+ P R Sbjct: 1247 QNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPGPRLRHSKSIDEGMFSAEPYLR------ 1300 Query: 195 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ--------RPASRSLSSSATPLSSPARS 246 + SA + A R GGG RP L+ A +SP Sbjct: 1301 -----LESAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGL 1355 Query: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP------ 300 +AR RA S+ G A +PP P + AP P SP A P Sbjct: 1356 ALAAR--ERALKESSE----GGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWG 1409 Query: 301 SAPPSPS-------APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP-----LS 348 ++PP P+ A Q S PA+PP+ + L H P+ P L Sbjct: 1410 ASPPDPARRELGYRAGLGSQE-KSLPASPPAARRSLL--------HRLPPTAPGVGPLLL 1460 Query: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSP--LATPSPQAP--NALAVHLLQAPFSPP 404 L T PP P ++ P A P P PL L P+AP + P PP Sbjct: 1461 QLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPP 1520 Query: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP-----------LQVPPSPPA----- 448 PSP P SP SP A+ + P + PP L V P PP Sbjct: 1521 PSPRRSVPPSP-----TSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSN 1575 Query: 449 --SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP--LQALPSPPASFPGQAP 504 P SP PP P AP L PP PPA+A P L + S S+ + Sbjct: 1576 SFEKPESPLTPGPPHPLPDTPAPATPL---PPVPPPAVAAAPPTLDSTASSLTSYDSEV- 1631 Query: 505 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 564 A+L A P PP P PA+P AP+ P P P T SG Sbjct: 1632 ----ATLTQGASAAPGDPHPP---------GPPAPAAPAPAAPQPGPDPPPGTD-SGIEE 1677 Query: 565 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSA---------TSTPEELRGYDSGPEG--- 612 + + P + S +STLS G S+ S PE L Y + +G Sbjct: 1678 VDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAF 1737 Query: 613 GAAASPPPDAELAACHP---------AAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADG 663 G +++P P P A+ P P R P TG G+ DG Sbjct: 1738 GGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGT-DG 1796 Query: 664 LCTIYETEGPESATPAPGAL------DPGPSPGTSGGKAAA-----GAGAGASSRSPKQA 712 L + GP +A A G + P P P S G G A Sbjct: 1797 LLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEEGPGPPPPPLPGPLA 1856 Query: 713 RLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVT--GGARAALSDA 770 + L ++AS++ L S+ + A G GG+ GGG + GGA Sbjct: 1857 QPQASALATVKASIISELSSKLQQFGGSSAAGGALPWARGGSGGGGDSHHGGASYV---- 1912 Query: 771 ELGRWAELLSPLDESRASITSVTSFSPDDVASPQGDW 807 E S L R S S +S V+S +W Sbjct: 1913 -----PERTSSLQRQRLSDDSQSSLLSKPVSSLFQNW 1944 Score = 90.5 bits (223), Expect = 6e-18 Identities = 193/742 (26%), Positives = 240/742 (32%), Gaps = 201/742 (27%) Query: 166 AMARRSRA---AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP----------S 212 A+A R RA + G P+P P P P E P + S H+ EP Sbjct: 1356 ALAARERALKESSEGGGAPQPPPRP-PSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPD 1414 Query: 213 PAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT----------PRAPAHPSQ 262 PA R G + S S A S R P+A G P AP HP Sbjct: 1415 PARRELGYRAGLGSQEKSLPASPPAARRSLLHRLPPTAPGVGPLLLQLGTEPPAP-HPGV 1473 Query: 263 PKPKGLQALRPPQVTP----------PRKDAAPALGPLSSSPLATPSPS----APPSPSA 308 KP A P+ P PR GP S P PS PPSP++ Sbjct: 1474 SKPWRSAAPEEPERLPLHVRFLENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTS 1533 Query: 309 PPS-----LQTLPSPPATPPSQATTSLG------SPTLQATHSFLPSPPLSPLATPPPQA 357 P + L L PP P P L+ ++SF P SPL PP Sbjct: 1534 PRASEENGLPLLVLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSF--EKPESPLTPGPPHP 1591 Query: 358 PPALALPPLQAPPSPP----ASPPLSPLATPSPQAPNALAVHLLQ----APFSP-PPSPP 408 P P PP PP A+PP S + ++ L Q AP P PP PP Sbjct: 1592 LPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPP 1651 Query: 409 VQAPFSP-PASPPVSPSATPPSQA------PPSLAAPPLQVPPSPPASPPMSP----SAT 457 AP +P PA+P P P + + S + PL+ S +S SA Sbjct: 1652 --APAAPAPAAPQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAG 1709 Query: 458 PPPQAPPPLAAPPLQL---------------AKPPPQAPPALATPPL---QALPSPPASF 499 A +A+ P L + P P PP L TP +AL + Sbjct: 1710 GGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLR 1769 Query: 500 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS-----PTLQAPRRPPTPG 554 PG + P SP + L A L+ PP + P P PP P Sbjct: 1770 PGPSGGLRDPVTPTSPTVSVTGAGTDGLLA--LRACSGPPTAGVAGGPVAVEPEVPPVPL 1827 Query: 555 PDTSVSGPRLTLAL--APGPPPPPSRSPSSTLSGPDLA-----------------GHSSS 595 P T+ S PR L PGPPPPP P + LA G SS+ Sbjct: 1828 P-TASSLPRKLLPWEEGPGPPPPPLPGPLAQPQASALATVKASIISELSSKLQQFGGSSA 1886 Query: 596 ATSTPEELRGYDSGP----EGGAAASPPPDAELAA------------CHPAA-----WSR 634 A RG G GGA+ P + L P + W + Sbjct: 1887 AGGALPWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQSSLLSKPVSSLFQNWPK 1946 Query: 635 GPAPPLAF-RGAPGAPLPWPPATGPGSADGLCTIYETEGPE------------------- 674 P PPL G P AT P ++ + +G E Sbjct: 1947 PPLPPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPA 2006 Query: 675 ---SATPAP----------GALDPG-------------------------PSPGTSGGKA 696 +PAP G L PG P PG SGG Sbjct: 2007 SEHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLG 2066 Query: 697 AAGAGAGASSRSPKQARLGELP 718 A +GA SRS RL LP Sbjct: 2067 GALSGA---SRSLSPTRLLSLP 2085 Score = 87.4 bits (215), Expect = 5e-17 Identities = 214/855 (25%), Positives = 272/855 (31%), Gaps = 179/855 (20%) Query: 17 PAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76 P + G LTP P G P P P L A G P R G + +S Sbjct: 937 PVPSSSGRLTPSPRGGPFNPGSGGP--LPASSPASFDGPSPPDTRVG-----SREKSLYH 989 Query: 77 AGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136 +GP PPA PP + P P P + G G Sbjct: 990 SGPL----PPA----HHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETG-----------G 1030 Query: 137 KATEAPKRSALS-----AGARRDTSGPTPGTPSPA-MARRSRAAGTEVG-------LPRP 183 + P R AL G R PTPG PSP+ G+ G LP Sbjct: 1031 SPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPR 1090 Query: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243 A SA P R + + E P GGGL P + S +S A+P P Sbjct: 1091 AASAAMYVPARSGRGRKGPLVKQTKVE------GEPQKGGGL--PPAPSPTSPASPQPPP 1142 Query: 244 ARSGPSARGT-------PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296 A + PS + + +AP+ S + + T P G S SP Sbjct: 1143 AVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAP 1202 Query: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356 SP PPSPS P+ PA+P AT T Q + + + + Sbjct: 1203 AMSP-VPPSPSPVPT-------PASPSGPATLDF---TSQFGAALVGAARREGGWQNEAR 1251 Query: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS-- 414 L L A L A P P+ ++ ++ + FS P +++ S Sbjct: 1252 RRSTLFL-STDAGDEDGGDGGLGTGAAPGPRLRHSKSID--EGMFSAEPYLRLESAGSGA 1308 Query: 415 --------PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP------------PMSP 454 A S+ S PP PL PASP S Sbjct: 1309 GYGGYGAGSRAYGGGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESS 1368 Query: 455 SATPPPQAPPPLAAPPLQLAKPPP--QAPPALATPPLQAL-PSPPASFPGQAPF-----S 506 PQ PP +P + P P +P A P L+ SPP + + S Sbjct: 1369 EGGGAPQPPPRPPSPRYEAPPPTPHHHSPHAHHEPVLRLWGASPPDPARRELGYRAGLGS 1428 Query: 507 PSASLPMSPLATP-------PPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTP----- 553 SLP SP A PP AP V LLQ+ PPA P + P R P Sbjct: 1429 QEKSLPASPPAARRSLLHRLPPTAPGV-GPLLLQLGTEPPAPHPGVSKPWRSAAPEEPER 1487 Query: 554 --------------GPDTSVSGPRLTLALAPG-PPPPPSRS-PSSTLSGPDLAGHSSSAT 597 P TS GP PG PPP P RS P S S + Sbjct: 1488 LPLHVRFLENCQPRAPVTSGRGP--PSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLL 1545 Query: 598 STPEELRGYDSGPEGGAAASP-PPDAELAACH---PAAWSRGPAPPLAFRGAPGAPLPWP 653 P D P PP E + + + GP PL AP PLP Sbjct: 1546 VLPPPAPSVDVEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPV 1605 Query: 654 P----ATGPGSADGLC---TIYETE-------------------GPESATPAPGALDPGP 687 P A P + D T Y++E P A PAP A PGP Sbjct: 1606 PPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGP 1665 Query: 688 SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGS 747 P + +SS P + +S L++ GGS Sbjct: 1666 DPPPGTDSGIEEVDSRSSSDHPLET------------------ISSASTLSSLSAEGGGS 1707 Query: 748 GGGPGGAEGGGVTGG 762 GG GGA G GV G Sbjct: 1708 AGGGGGA-GAGVASG 1721 Score = 74.7 bits (182), Expect = 3e-13 Identities = 148/582 (25%), Positives = 197/582 (33%), Gaps = 86/582 (14%) Query: 166 AMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPS---AG 222 A A+++ +A G A + RP +G + SS H +PS RPS G Sbjct: 827 AAAQQTISASESPGPGGLASLGKHRP--KGFFATESSFDPHHRAQPS---YERPSFLPPG 881 Query: 223 GGLQRPASRSLSSSATPLSSPARSGPSARGTPR--APAHPSQPKPKGLQALRPPQVTPP- 279 GL R S A P + P+ + + P P P PP TPP Sbjct: 882 PGLML---RQKSIGAAEDDRPYLAPPAMKFSRSLSVPGSEDIPPPPTTSPPEPPYSTPPV 938 Query: 280 -----RKDAAPALGPL---SSSPLATPSPSAPPSPSAPPS---------LQTLPSPPA-- 320 R +P GP S PL SP++ PS P + + P PPA Sbjct: 939 PSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHH 998 Query: 321 TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA-------PPSPP 373 PP P H+ P PP P PP LAL P + PSP Sbjct: 999 HPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPT 1058 Query: 374 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433 P SP S + F PP A + P S P Sbjct: 1059 PGAP-SPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARS---GRGRKGPLVKQT 1114 Query: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493 + P + PPA P SP++ PQ PP +AAP + + P P + Sbjct: 1115 KVEGEPQKGGGLPPAPSPTSPAS---PQPPPAVAAPSEKNSIPIPTI----------IIK 1161 Query: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQ-------APPVLAAPLLQVPPSPPASPTLQA 546 +P S G++ S +S P P P + P A + VPPSP PT + Sbjct: 1162 APSTSSSGRS--SQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSPVPTPAS 1219 Query: 547 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPS----STLSGPDLAGHSSSATSTP-- 600 P P T + + A G +R S ST +G + G T Sbjct: 1220 PSGPATLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGDGGLGTGAAPG 1279 Query: 601 EELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA----------PL 650 LR S EG +A P E +A A + A A+ G G+ PL Sbjct: 1280 PRLRHSKSIDEGMFSAEPYLRLE-SAGSGAGYGGYGAGSRAYGGGGGSSAFTSFLPPRPL 1338 Query: 651 PWP---PATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689 P A P S GL + ++ GA P P P Sbjct: 1339 VHPLTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRP 1380 Score = 66.6 bits (161), Expect = 9e-11 Identities = 153/622 (24%), Positives = 212/622 (34%), Gaps = 76/622 (12%) Query: 1 MDNKRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAE 60 ++N + +A + P+ PG+ P P S PP P +P A G V P Sbjct: 1495 LENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSV-PPSPTSPRASEENGLPLLVLPPPAPS 1553 Query: 61 RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGP 119 G E P PP P +PGP P + T P Sbjct: 1554 VDVEDGEFLFVEPLP---------PPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPP 1604 Query: 120 LGQKGLRISAE--ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177 + + + ++ A + + + L+ GA P P P PA A + AA Sbjct: 1605 VPPPAVAAAPPTLDSTASSLTSYDSEVATLTQGASAAPGDPHPPGP-PAPAAPAPAA--- 1660 Query: 178 VGLPRPAPSARP-----------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226 P+P P P R ++ P +++SSAS T S +A SAGGG Sbjct: 1661 ---PQPGPDPPPGTDSGIEEVDSRSSSDHPLETISSAS----TLSSLSAEGGGSAGGGGG 1713 Query: 227 RPAS-----RSLSSSATPLSSPARSGPSARGTPRAP--AHPSQPKPKGLQA---LRPPQV 276 A L + L A G S G P P PS+ + + L A LRP Sbjct: 1714 AGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLMTPSKLRGRALGASGGLRPGPS 1773 Query: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP----PATPPSQATTSLGS 332 R P +S + T A + S PP+ P P PP T+ Sbjct: 1774 GGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSL 1833 Query: 333 PTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392 P P PP PL P Q P A AL ++A S L S A AL Sbjct: 1834 PRKLLPWEEGPGPPPPPLPGPLAQ-PQASALATVKASIISELSSKLQQFG-GSSAAGGAL 1891 Query: 393 A-----------VHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ 441 H A + P + +Q S S + P S + PPL Sbjct: 1892 PWARGGSGGGGDSHHGGASYVPERTSSLQRQRLSDDSQS-SLLSKPVSSLFQNWPKPPL- 1949 Query: 442 VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP---PAS 498 P P +SP+A P A P A+ + + P L+ PSP PAS Sbjct: 1950 --PPLPTGTGVSPTAAAAPGATSPSASSSSTSTRHLQGVEFEMRPPLLRRAPSPSLLPAS 2007 Query: 499 FPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-PPASPTLQAPRRPPTPGPDT 557 +P +SLP+ P P + +P S P +P P + G Sbjct: 2008 EHKVSPAPRPSSLPILPSGPLYPGLFDIRGSPTGGAGGSADPFAPVFVPPHPGISGGLGG 2067 Query: 558 SVSG------PRLTLALAPGPP 573 ++SG P L+L P P Sbjct: 2068 ALSGASRSLSPTRLLSLPPDKP 2089 Score = 63.9 bits (154), Expect = 6e-10 Identities = 151/600 (25%), Positives = 196/600 (32%), Gaps = 135/600 (22%) Query: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324 P+ + L PP ++ K L + P PS + Sbjct: 771 PQQAKRLPPPTISLRSKSMTSELEEMEYEQQPAPVPSMEKKRTVYQMALNKLDEILAAAQ 830 Query: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSP---- 380 Q ++ SP S P AT P A P + P P P L Sbjct: 831 QTISASESPGPGGLASLGKHRPKGFFATESSFDPHHRAQPSYERPSFLPPGPGLMLRQKS 890 Query: 381 ----------LATPSPQAPNALAVHLLQAPFSPP-PSPPVQAPFSPPAS-PPVSPSA--- 425 LA P+ + +L+V P S P PP +P PP S PPV S+ Sbjct: 891 IGAAEDDRPYLAPPAMKFSRSLSV-----PGSEDIPPPPTTSPPEPPYSTPPVPSSSGRL 945 Query: 426 ---------TPPSQAPPSLAAPPLQVPPSPP------------ASPPMSPSATPPP---- 460 P S P ++P PSPP S P+ P+ PP Sbjct: 946 TPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGPLPPAHHHPPHHHH 1005 Query: 461 -QAPPPL-----AAPP----LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510 APPP A PP ++ P PP LA P +L P P +PS S Sbjct: 1006 HHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRGGGPSPTPGAPSPS 1065 Query: 511 LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRP--PTPGP---DTSVSG-PRL 564 S P L Q+PP AS + P R GP T V G P+ Sbjct: 1066 HHGSAGGGGGSSQGPALR--YFQLPPR-AASAAMYVPARSGRGRKGPLVKQTKVEGEPQK 1122 Query: 565 TLALAPGP---------PPPPSRSPSSTLSGP-----------DLAGHSSSATSTPEE-- 602 L P P PPP +PS S P +G SS +ST E Sbjct: 1123 GGGLPPAPSPTSPASPQPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPP 1182 Query: 603 LRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA-TGPGSA 661 + +G GG +SP P A + P PP +P+P P + +GP + Sbjct: 1183 TQPEPTGGGGGGGSSPSP----------APAMSPVPP------SPSPVPTPASPSGPATL 1226 Query: 662 D-----GLCTI--------YETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 708 D G + ++ E +T + D G G GG G GA R Sbjct: 1227 DFTSQFGAALVGAARREGGWQNEARRRSTLFL-STDAGDEDGGDGG---LGTGAAPGPRL 1282 Query: 709 PKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGARAALS 768 + E G A L S A GA G G A GGG GG+ A S Sbjct: 1283 RHSKSIDE---GMFSAEPYLRLES------AGSGAGYGGYGAGSRAYGGG--GGSSAFTS 1331 Score = 40.0 bits (92), Expect = 0.009 Identities = 48/155 (30%), Positives = 62/155 (40%), Gaps = 41/155 (26%) Query: 643 RGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALD---PGPSPG--------- 690 RG PG L PPA ++D + + APGA PGP+ G Sbjct: 421 RGPPGTGLTVPPALLRANSDTSMALPDW----MVFSAPGAASSGAPGPTSGSQGQSQPSA 476 Query: 691 -----TSGGKAAAGAGAGASSRSPKQARLGE----LPLGALQASVVQHLLSRTLLLAAAE 741 +SG +A + GA +RSP + R E P G +S E Sbjct: 477 PTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRPSSSGTPR-----------E 525 Query: 742 GAAGGSG--GGPGGAEGGGVTGGARAALSDAELGR 774 G AGG+G GGPGG+ G + G R L A GR Sbjct: 526 GPAGGTGGSGGPGGSLG---SRGRRRKLYSAVPGR 557 Score = 33.5 bits (75), Expect = 0.82 Identities = 25/80 (31%), Positives = 33/80 (41%), Gaps = 6/80 (7%) Query: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAG----GGLQRPASRSLS 234 G P P ++ + P +SS + S + P A R PS G ++P R S Sbjct: 460 GAPGPTSGSQGQSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGRP-S 518 Query: 235 SSATPLSSPARSGPSARGTP 254 SS TP PA G G P Sbjct: 519 SSGTPREGPA-GGTGGSGGP 537 >gi|55750053 atrophin-1 [Homo sapiens] Length = 1190 Score = 125 bits (315), Expect = 1e-28 Identities = 176/702 (25%), Positives = 240/702 (34%), Gaps = 164/702 (23%) Query: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194 R K P+ S G R + G + S A +SR + R ++ P+ + Sbjct: 16 RKKEAPGPREELRSRG--RASPGGVSTSSSDGKAEKSRQTAKKA---RVEEASTPKVNKQ 70 Query: 195 GPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLS---------------S 235 G + +S + T P RP + L RSL+ S Sbjct: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130 Query: 236 SATPLSSPA---RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292 ++ + SP S+ G + PA P P P L PP PP D+ P S Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP-----LFPPSPQPP--DSTPRQPEASF 183 Query: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352 P + +P+ +P PP+ + +PP PP G T L PP+ P Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG-----TGGVLSGPPMGPKGG 238 Query: 353 ---------------PPPQAPPALALPPLQAPPSPPASPPLSPLATPS-PQAPNALAVHL 396 PPP P +++ A +PP PP +P+ + P AP Sbjct: 239 GAASSVGGPNGGKQHPPPTTP--ISVSSSGASGAPPTKPPTTPVGGGNLPSAP------- 289 Query: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPS 455 PP + P P PP PP S +PP L A PL PSP A Sbjct: 290 ------PPANFPHVTPNLPP--PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341 Query: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ------------ALPSPPASFPGQA 503 P P+ P LA P L P A + PP++ A S +S + Sbjct: 342 LPPGPEKGPTLAPSPHSL----PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397 Query: 504 PFSPSASLPMSPLATPPPQA------PPVLAAPLL-------QVPPSPPASPTLQAPRR- 549 PF S +LP P + PPP + PP P L Q PP PP L A Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457 Query: 550 -----PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPS 581 PP+ G ++ P T PPPP P Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH 517 Query: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AAC 627 G H + + + LR Y GP A PPP +++ ++ Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 628 HPAAWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGAL 683 ++ S+G P P +G GAP P+PP T S+ L T+ T S A Sbjct: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTAS 632 Query: 684 DPGPSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 718 PGP P GK A GA G SP R G P Sbjct: 633 PPGPPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671 Score = 116 bits (291), Expect = 7e-26 Identities = 166/655 (25%), Positives = 225/655 (34%), Gaps = 109/655 (16%) Query: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP--PA 87 P P PPP+ P + + + R+P A E P PT P P Sbjct: 155 PARPYHPPPLFPPSPQ---PPDSTPRQPEASF----------EPHPSVTPTGYHAPMEPP 201 Query: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147 + R +APP P P PG G P+G KG ++ G P + + Sbjct: 202 TSRMFQAPPGA-PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI 260 Query: 148 SAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206 S + + P P+ P +A P P+ P PP P + S++ Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPP-PPALRPLNNASASPPG 319 Query: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA--PAHPSQPK 264 +P P P+ ++ L GP+ +P + PA S P Sbjct: 320 LGAQPLPG-----------HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368 Query: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS------APPSLQTLPSP 318 P +R P + AA + SSS A+P P++ PS P SL P Sbjct: 369 PP----MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424 Query: 319 PA----TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA------ 368 P + PSQA S G P L + P PP + A PP+ Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484 Query: 369 ------------------------PPSPPASP-PL----SPLATPSPQAPN--ALAVHLL 397 PP P A P PL S A P +P+ +L + Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544 Query: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--------PSLAAPPLQVP-PSPPA 448 PPP V + P PPVS S+ S PS + P P P PP Sbjct: 545 GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604 Query: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP-----------ALATPPLQALPSPPA 497 + SAT ++P PP PP ATPP SPP+ Sbjct: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPS 664 Query: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557 G P S P P T P +P V PL P P P+L P P GP Sbjct: 665 FRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPL 721 Query: 558 SVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608 S + + A P P PP+RSPS D+ H+S + + L RG++S Sbjct: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776 Score = 112 bits (281), Expect = 1e-24 Identities = 148/525 (28%), Positives = 189/525 (36%), Gaps = 78/525 (14%) Query: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG------GATIPESAPRAGPTRT 82 P G + PPP TP ++ GA+GA KP GG A P P P Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306 Query: 83 SRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138 RP AS G A P P P + G+ G PGP +KG T+A Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAPSPH 357 Query: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198 + P S+ A R + + S A A S ++ + P PA A P P P Sbjct: 358 SLPPASSSAPAPPMRFPYSSS--SSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP 415 Query: 199 SVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSS-ATPLSSPARSGPSARGTPR 255 + S S T+PS ++ S G P R L++S A P P +G + P Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475 Query: 256 APAHPSQPKPKGLQALRPPQVT-----------PPRKDAAPALGPLSSSPLATP---SPS 301 H + + Q + Q PP A P SS A P SPS Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535 Query: 302 APPSPSAPPSLQTLPSP----------PATPPSQATTSLGSPTLQATHSFL-PSPPLSPL 350 PP LP P P PP ++++ S T Q ++ PSP P Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQ 595 Query: 351 ATPPPQAP----------------PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394 P P P + P SPP PP A PSP A Sbjct: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKTAT- 653 Query: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454 P P SPP +PP SP A P + P S P + P PPA P P Sbjct: 654 ----PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPGPLPPAGPSGLP 706 Query: 455 SATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496 S PPP AP PPL+A ++ P PP ++ PSPP Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-PSPP 750 >gi|55750041 atrophin-1 [Homo sapiens] Length = 1190 Score = 125 bits (315), Expect = 1e-28 Identities = 176/702 (25%), Positives = 240/702 (34%), Gaps = 164/702 (23%) Query: 135 RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE 194 R K P+ S G R + G + S A +SR + R ++ P+ + Sbjct: 16 RKKEAPGPREELRSRG--RASPGGVSTSSSDGKAEKSRQTAKKA---RVEEASTPKVNKQ 70 Query: 195 GPRKSVSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLS---------------S 235 G + +S + T P RP + L RSL+ S Sbjct: 71 GRSEEISESESEETNAPKKTKTEQELPRPQSPSDLDSLDGRSLNDDGSSDPRDIDQDNRS 130 Query: 236 SATPLSSPA---RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 292 ++ + SP S+ G + PA P P P L PP PP D+ P S Sbjct: 131 TSPSIYSPGSVENDSDSSSGLSQGPARPYHPPP-----LFPPSPQPP--DSTPRQPEASF 183 Query: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352 P + +P+ +P PP+ + +PP PP G T L PP+ P Sbjct: 184 EPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPPHPQLYPGG-----TGGVLSGPPMGPKGG 238 Query: 353 ---------------PPPQAPPALALPPLQAPPSPPASPPLSPLATPS-PQAPNALAVHL 396 PPP P +++ A +PP PP +P+ + P AP Sbjct: 239 GAASSVGGPNGGKQHPPPTTP--ISVSSSGASGAPPTKPPTTPVGGGNLPSAP------- 289 Query: 397 LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASPPMSPS 455 PP + P P PP PP S +PP L A PL PSP A Sbjct: 290 ------PPANFPHVTPNLPP--PPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGG 341 Query: 456 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQ------------ALPSPPASFPGQA 503 P P+ P LA P L P A + PP++ A S +S + Sbjct: 342 LPPGPEKGPTLAPSPHSL----PPASSSAPAPPMRFPYSSSSSSSAAASSSSSSSSSSAS 397 Query: 504 PFSPSASLPMSPLATPPPQA------PPVLAAPLL-------QVPPSPPASPTLQAPRR- 549 PF S +LP P + PPP + PP P L Q PP PP L A Sbjct: 398 PFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNA 457 Query: 550 -----PPTPGPDTSVSGPRLT-----------------------LALAPGPPPPPSRSPS 581 PP+ G ++ P T PPPP P Sbjct: 458 HPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPH 517 Query: 582 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAEL--------------AAC 627 G H + + + LR Y GP A PPP +++ ++ Sbjct: 518 PLEGGSSHHAHPYAMSPSLGSLRPYPPGP----AHLPPPHSQVSYSQAGPNGPPVSSSSN 573 Query: 628 HPAAWSRGPAP---PLAFRGAPGAPLPWPPA-TGPGSADGLCTIYETEGPESATPAPGAL 683 ++ S+G P P +G GAP P+PP T S+ L T+ T S A Sbjct: 574 SSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLSTVIATVA-SSPAGYKTAS 632 Query: 684 DPGPSPGTSGGKAAAGAGA-------GASSRSPKQARLGELP 718 PGP P GK A GA G SP R G P Sbjct: 633 PPGPPP---YGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPP 671 Score = 116 bits (291), Expect = 7e-26 Identities = 166/655 (25%), Positives = 225/655 (34%), Gaps = 109/655 (16%) Query: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP--PA 87 P P PPP+ P + + + R+P A E P PT P P Sbjct: 155 PARPYHPPPLFPPSPQ---PPDSTPRQPEASF----------EPHPSVTPTGYHAPMEPP 201 Query: 88 SGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSAL 147 + R +APP P P PG G P+G KG ++ G P + + Sbjct: 202 TSRMFQAPPGA-PPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPI 260 Query: 148 SAGARRDTSGPTPGTPS-PAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEH 206 S + + P P+ P +A P P+ P PP P + S++ Sbjct: 261 SVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPP-PPALRPLNNASASPPG 319 Query: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA--PAHPSQPK 264 +P P P+ ++ L GP+ +P + PA S P Sbjct: 320 LGAQPLPG-----------HLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA 368 Query: 265 PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS------APPSLQTLPSP 318 P +R P + AA + SSS A+P P++ PS P SL P Sbjct: 369 PP----MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424 Query: 319 PA----TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA------ 368 P + PSQA S G P L + P PP + A PP+ Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484 Query: 369 ------------------------PPSPPASP-PL----SPLATPSPQAPN--ALAVHLL 397 PP P A P PL S A P +P+ +L + Sbjct: 485 QQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPP 544 Query: 398 QAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAP--------PSLAAPPLQVP-PSPPA 448 PPP V + P PPVS S+ S PS + P P P PP Sbjct: 545 GPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPV 604 Query: 449 SPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPP-----------ALATPPLQALPSPPA 497 + SAT ++P PP PP ATPP SPP+ Sbjct: 605 PTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPS 664 Query: 498 SFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557 G P S P P T P +P V PL P P P+L P P GP Sbjct: 665 FRTGTPPGYRGTSPPAGP-GTFKPGSPTVGPGPL--PPAGPSGLPSLPPPPAAPASGPPL 721 Query: 558 SVSGPRLTLA---LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL-RGYDS 608 S + + A P P PP+RSPS D+ H+S + + L RG++S Sbjct: 722 SATQIKQEPAEEYETPESPVPPARSPSPPPKVVDVPSHASQSARFNKHLDRGFNS 776 Score = 112 bits (281), Expect = 1e-24 Identities = 148/525 (28%), Positives = 189/525 (36%), Gaps = 78/525 (14%) Query: 29 PPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG------GATIPESAPRAGPTRT 82 P G + PPP TP ++ GA+GA KP GG A P P P Sbjct: 247 PNGGKQHPPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSAPPPANFPHVTPNLPPPPA 306 Query: 83 SRP----PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 138 RP AS G A P P P + G+ G PGP +KG T+A Sbjct: 307 LRPLNNASASPPGLGAQPLPGHLPSP-HAMGQGMGGLPPGP--EKG------PTLAPSPH 357 Query: 139 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRK 198 + P S+ A R + + S A A S ++ + P PA A P P P Sbjct: 358 SLPPASSSAPAPPMRFPYSSS--SSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPP 415 Query: 199 SVSSASEHST--TEPSPAARRRPSAGGGLQRPASRSLSSS-ATPLSSPARSGPSARGTPR 255 + S S T+PS ++ S G P R L++S A P P +G + P Sbjct: 416 TSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPP 475 Query: 256 APAHPSQPKPKGLQALRPPQVT-----------PPRKDAAPALGPLSSSPLATP---SPS 301 H + + Q + Q PP A P SS A P SPS Sbjct: 476 VSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPS 535 Query: 302 APPSPSAPPSLQTLPSP----------PATPPSQATTSLGSPTLQATHSFL-PSPPLSPL 350 PP LP P P PP ++++ S T Q ++ PSP P Sbjct: 536 LGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPSQGPQ 595 Query: 351 ATPPPQAP----------------PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394 P P P + P SPP PP A PSP A Sbjct: 596 GAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRA-PSPGAYKTAT- 653 Query: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454 P P SPP +PP SP A P + P S P + P PPA P P Sbjct: 654 ----PPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGS---PTVGPGPLPPAGPSGLP 706 Query: 455 SATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496 S PPP AP PPL+A ++ P PP ++ PSPP Sbjct: 707 SLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-PSPP 750 >gi|150170670 piccolo isoform 2 [Homo sapiens] Length = 4935 Score = 124 bits (312), Expect = 3e-28 Identities = 155/606 (25%), Positives = 222/606 (36%), Gaps = 97/606 (16%) Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAG-------- 78 G+ P PA + L R+ +A RA G+ ++P +A + Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87 Query: 79 -----PTRTSRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 128 P ++ RPP GR + +K+ + S PGR+ T + + L+ Sbjct: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147 Query: 129 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 182 + ++ G +E SA+S+ + D + + ++ + E G P Sbjct: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206 Query: 183 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 P P + + P P + + S+ +P + P G +Q P Sbjct: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266 Query: 234 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAP 285 + A PL A + RG P+ PS KP Q +PP P + + P Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT--PPSQATTSLGSPTLQATHSFLP 343 GP + P A PS P P +++ PP T PP+Q P Q T S P Sbjct: 327 --GP--AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKP 381 Query: 344 SPPLSPLATPPPQA---PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400 S P P+A PP + P Q P PA PP + TP P A +AP Sbjct: 382 SSE-----QPGPKALAQPPGVGKTPAQQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460 P PVQ P P P QA P + P PP+ P A PPP Sbjct: 435 --GPTKTPVQQP---------GPGKIPAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPPP 481 Query: 461 QAPPPLAAPPLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518 Q P P PP Q AKPP Q P + PP Q P+ P+ P P +T Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS--------------PQQPGST 527 Query: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 PP P A P Q P PA P+ Q +P + T P ++P PPS+ Sbjct: 528 KPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTGSGKPLQPPTVSPSAKQPPSQ 582 Query: 579 SPSSTL 584 T+ Sbjct: 583 GLPKTI 588 Score = 113 bits (282), Expect = 8e-25 Identities = 176/718 (24%), Positives = 256/718 (35%), Gaps = 126/718 (17%) Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62 RD + ++ +++ P + +PPG+ +P P TP +P ++A Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286 Query: 63 GGIGGATI------PESAPRAGPTRTSRPPA-------SGRGERAPPAKNTS-------- 101 + G ++ P P PT +PPA S G PPA+ + Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345 Query: 102 PGPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 159 PG V P + GTT+P PLG + A++T + ++E P AL A+ G T Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKT 400 Query: 160 PGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218 P P PA + +VG P+P +P + P K+ ++ +P P Sbjct: 401 PAQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPA 451 Query: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278 AG G + + L PA+ P G + P P QP + +P P Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKP 509 Query: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338 P + PA P P +T PS P SA PS Q PSP A P +Q +T S T + Sbjct: 510 PPQQPGPAK-PSPQQPGSTKPPSQQPG-SAKPSAQQ-PSP-AKPSAQQSTKPVSQT--GS 563 Query: 339 HSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLAT-------------- 383 L P +SP A PP Q P P P + T Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF 623 Query: 384 -PSPQAP--------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434 P+P N L +P PS P + P + + S + P Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ----- 678 Query: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPPQ-------AP 481 P Q P A+P S P P+ PPPL P AK PP+ AP Sbjct: 679 ----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAP 734 Query: 482 PALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 P + P + +P A + P P+ L S AT P P + +PP Sbjct: 735 PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP 794 Query: 540 ASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 P + PPT G +++ + P P S S + GP S Sbjct: 795 LKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP---SSESKGQ 843 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655 + ++ + + SP PDA+ P P +G+P P P P A Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPTPPGPRPTA 885 Score = 108 bits (270), Expect = 2e-23 Identities = 178/746 (23%), Positives = 268/746 (35%), Gaps = 154/746 (20%) Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65 P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+ Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397 Query: 66 GGATIPESAPRAGPTR---TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PL 120 G + P PT+ T +P A G ++P +PGP +P + G PG P Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK---APGPTKTPVQQPG---PGKIPA 451 Query: 121 GQKGL-RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179 Q G + SA++T T+ P S L A+ P P P P ++ + G Sbjct: 452 QQAGPGKTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 180 LPRPAPS----ARP--------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 227 +P P A+P +PP++ P + SA + S +PS +P + G + Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Query: 228 PASRSLSSSATPLSSPARSGPSARGTPRA---------------------PAHPSQPKPK 266 P P SP+ P ++G P+ Q Sbjct: 566 PLQ-------PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618 Query: 267 GLQALRP-PQVTPPRK--------------DAAPALGP----LSSSPLATPSPSAPPSPS 307 L P P +T ++ D AP L ++P+ T S S S Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS---AVSKS 675 Query: 308 APPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364 +P QT P A P S+A P L + SP S A PP+A +L+ P Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP--SAKAKQPPEA-DSLSKP 732 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPAS 418 PS P+ +P+A P+ P + V A P PS VQ+ + Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 PP+ + PSQ+ PP+ P A P P + + + P P Sbjct: 793 PPLKTDSAKPSQS----------FPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSS 838 Query: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 ++ P+Q P + Q SP P +P P P P Sbjct: 839 ESKGQKQVDPVQKKEEPKKA---QTKMSPKPDAKPMPKGSPTPPG------------PRP 883 Query: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSA 596 A T+ P++ P P + R +L L P S+ +P T++G L G +S Sbjct: 884 TAGQTVPTPQQSPKPQEQSR----RFSLNLGSITDAPKSQPTTPQETVTG-KLFGFGASI 938 Query: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 S L A P P ++ P + P+ P +G P + PPA Sbjct: 939 FSQASNLI--------STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA- 989 Query: 657 GPGSADGLCTIYETEGPESATPAPGA 682 A + ET+ P + P A Sbjct: 990 ---PAKSIPVKKETKAPAAEKLEPKA 1012 Score = 108 bits (269), Expect = 3e-23 Identities = 188/766 (24%), Positives = 264/766 (34%), Gaps = 132/766 (17%) Query: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT-SRPP 86 +PP +PP P+ GR PL + P+S P + S+PP Sbjct: 208 KPPLQQQPPKPIPKQQ--------GPGRDPLQQDG-------TPKSISSQQPEKIKSQPP 252 Query: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEET-VARGKATEAPKR 144 +G+ P+ P + T PL + R ++ + RG++ + Sbjct: 253 GTGK-------------PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV----K 295 Query: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA-----PSARPRPPTEGPRKS 199 +L + ++ PTPG P ++ G E P PA PS +P + P Sbjct: 296 PSLPSPSKPPIQQPTPGKPP------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349 Query: 200 VSSASEHSTTEP--SPAARRRPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 TT+P P +P A G ++P+S A L+ P P TP Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQP----PGVGKTPAQ 403 Query: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP 316 P++P + + +P P + A A GP + +P+ P P P+ A P + Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP-TKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376 T P P Q P P A PP Q P + PP Q P+ P+ Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS-- 520 Query: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPP-VSPSA-TPP 428 P P +T P A Q P PS P Q P PP VSPSA PP Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580 Query: 429 SQAPPSLAAP-------PLQVPPSPPASPPMSPSAT--------PPPQAP---------- 463 SQ P P L VP + T P P Sbjct: 581 SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640 Query: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA-SLPMSPL--ATPP 520 A LA P P L T P+ + S P SP + P L A P Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700 Query: 521 PQAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 + PP++ P L PS PP + +L P P P SV + +A P Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP----SVPSEQDKAPVADDKPKQ 756 Query: 576 PSR--------SPSSTLSGPDLAG---HSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624 P S SS + PD+ S + T L+ + P + S PP E Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP----SQSFPPTGEK 812 Query: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA----TPAP 680 + + PA PG P + G D + + E P+ A +P P Sbjct: 813 VSPFDSKAIPRPASDSKIISHPG---PSSESKGQKQVD---PVQKKEEPKKAQTKMSPKP 866 Query: 681 GALD-PGPSPGTSGGKAAAGAGAGASSRSPK---QARLGELPLGAL 722 A P SP G + AG +SPK Q+R L LG++ Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912 Score = 105 bits (262), Expect = 2e-22 Identities = 108/408 (26%), Positives = 146/408 (35%), Gaps = 49/408 (12%) Query: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258 S S AS+ TT+ ++ G+ +P + P + P +G R P Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPGRDPL 230 Query: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318 PK + + +P ++ K P G P TP P LQ S Sbjct: 231 Q-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLP-----LQRDASR 280 Query: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378 P T QA G ++ LPSP P+ P P PPA ++ P P A PP Sbjct: 281 PQT--KQADIVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPA 333 Query: 379 SP--LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436 P L P Q P + + + PP+ P+ P PPA S + P +LA Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALA 392 Query: 437 APPLQVPPSP-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPP 488 PP V +P PA PP TP P A P P + P P Q P P Sbjct: 393 QPP-GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451 Query: 489 LQALPS-----------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537 QA P PP+ PG A P P P P A P P PP Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511 Query: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585 P +P++P + P + G A P P P ++ + +S Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559 Score = 99.4 bits (246), Expect = 1e-20 Identities = 141/590 (23%), Positives = 192/590 (32%), Gaps = 82/590 (13%) Query: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226 +A + A G G P+ +A P G +S SE + + R G Sbjct: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71 Query: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 283 PA+ S + P G P P P+QP K + R Q P R Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128 Query: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343 +P+ L S T S P L + + A + + S Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188 Query: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ--APNALAVHLLQAPF 401 + + P + PPLQ P P P P Q P +++ + Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIK 248 Query: 402 SPPPSP--PVQAPFSPP----ASPPVSPSATPPSQAP-------------PSLAAPPLQ- 441 S PP P+Q P P A P+ A+ P PS + PP+Q Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308 Query: 442 -VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP---------PPQAPPALATPPLQA 491 P PPA P + P P PP A P L KP PP PP PP Q Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPP---AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP 365 Query: 492 L--PSPPASFPGQAPFSPSASLPMSPLATPPP-------QAPPVLAAPLLQV-PPSPPAS 541 L PPA G PS+ P PP Q P P QV P P A Sbjct: 366 LGPAKPPAQQTGSE--KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 542 -PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-LAGHSSSATST 599 P LQ+P + P GP T PGP P++ +GP + + T Sbjct: 424 QPGLQSPAKAP---------GPTKTPVQQPGPGKIPAQQ-----AGPGKTSAQQTGPTKP 469 Query: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 P +L G P + PP + + P + G P + P P P P + Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS--- 526 Query: 660 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709 T ++ P SA P+ P K + G+G + P Sbjct: 527 ------TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 80.5 bits (197), Expect = 6e-15 Identities = 135/617 (21%), Positives = 206/617 (33%), Gaps = 86/617 (13%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP----PVTPAALRVLGA--AGAVGRKP 57 K + G+ P P +P+ PGS +PP P+A + A + KP Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 58 LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117 +++ G P P P+ +PP+ G + P NT+ + P +A+ T Sbjct: 558 VSQTGSG-----KPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT-- 609 Query: 118 GPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPSPAM 167 + TV TE + L+ +R G P P +P P + Sbjct: 610 --------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661 Query: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSAGGG 224 + V P P P++ +S A E P P PSA Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA-KA 720 Query: 225 LQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQV-- 276 Q P + SLS A P + S P A P+ P P+ A P + Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780 Query: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPS--APPSLQTLPSPPA-----TPPSQATTS 329 + + A P + A PS S PP+ +P + +P P + + P ++ S Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840 Query: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389 G + +P P A P +P + P+PP P + P+PQ Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKP---MP--KGSPTPPGPRPTAGQTVPTPQ-- 893 Query: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 Q+P S P S TP L + AS Sbjct: 894 --------QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI--FSQAS 943 Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL---QALPSPPASFPGQAPFS 506 +S + P P + AP Q P P PP PP QA P+P S P + Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001 Query: 507 PSASLPMSPLATPPP---------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557 A+ + P A P + PP+ + L P PT + +P P++ Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT----KLEKSPKPES 1057 Query: 558 SVSGPRLTLALAPGPPP 574 + + L + PP Sbjct: 1058 TCPLCKTELNIGSKDPP 1074 Score = 61.6 bits (148), Expect = 3e-09 Identities = 80/310 (25%), Positives = 117/310 (37%), Gaps = 49/310 (15%) Query: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365 PS PS+ +LP+ P P ++SL S P PP P PPP PP Sbjct: 2377 PSGSPSVSSLPAKPR--PFFRSSSLDI-------SAQPPPPPPPPPPPPPPPPP------ 2421 Query: 366 LQAPPSPPASPPLSPLATPSPQ------APNALAVHLLQAPFSPPPSPPVQAPFSP---- 415 PP PP PP SP T P+ +P A L A + + +++ P Sbjct: 2422 ---PPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI 2478 Query: 416 --PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQ 472 A PPV P PS P L P PP +P P+ P Q P + P Sbjct: 2479 CTTAPPPVPPK---PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535 Query: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532 L+ L T LPSP +P SP ++ + P + + ++ Sbjct: 2536 LSLTSSMT-LNLVTSADYKLPSP------TSPLSPHSN------KSSPRFSKSLTETYVV 2582 Query: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLA 590 PS P +PT + + T P S S +++ + PP P S+ ++ Sbjct: 2583 ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYIS 2642 Query: 591 GHSSSATSTP 600 G + ++TP Sbjct: 2643 GALQTFSATP 2652 Score = 59.7 bits (143), Expect = 1e-08 Identities = 62/211 (29%), Positives = 79/211 (37%), Gaps = 30/211 (14%) Query: 416 PAS--PPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472 PAS P SPS + P++ P + L + PP PP P PPP PPP PP Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 473 LAKPP--PQAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLAT--PPPQAPPVL 527 KP P+ +A+P A P A + S LP++ + T PPP P Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 Query: 528 AAPLLQV------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG---------- 571 + P V P PP +P P+ P T T + L+L Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551 Query: 572 ---PPPPPSRSPSSTLSGPDLAGHSSSATST 599 P P SP S S P S S T T Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRF---SKSLTET 2579 Score = 59.3 bits (142), Expect = 1e-08 Identities = 85/361 (23%), Positives = 129/361 (35%), Gaps = 68/361 (18%) Query: 224 GLQRPASRSLSSSATPLSSPARSGP---------SARGTPRAPAHPSQPKPKGLQALRPP 274 G ++PAS+ S S + S PA+ P SA+ P P P P P PP Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---PPPPPP 2424 Query: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334 PP P + P +A+P +A P A +L+T T L S Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET------------TAVLRSNG 2472 Query: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAP---- 389 L T +PP P+ P P L P PP +P P+ P + Q P Sbjct: 2473 LPVTRICTTAPP--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530 Query: 390 ---------NALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSAT--------PPSQA 431 +++ ++L+ + PSP +P S +SP S S T P Sbjct: 2531 PKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG 2590 Query: 432 PPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP----------QA 480 P+ ++ + P SP S P PP+ A + ++ A Sbjct: 2591 TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSA 2650 Query: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPP 539 P A QA P+ F + + + ++ AP V L++ + +PP P Sbjct: 2651 TPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703 Query: 540 A 540 A Sbjct: 2704 A 2704 Score = 53.5 bits (127), Expect = 8e-07 Identities = 81/339 (23%), Positives = 114/339 (33%), Gaps = 61/339 (17%) Query: 243 PARSGPSARGTPRAPAHPSQPKP------KGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296 PA PS G+P + P++P+P + A PP PP Sbjct: 2372 PASQLPS--GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP----------------- 2412 Query: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356 P P PP P PP L SP T + ++ SP AT F L A Sbjct: 2413 -PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSN 2471 Query: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416 P + PP PP P + PS L P PS P P Sbjct: 2472 GLPVTRICTTAPPPVPP-----KPSSIPSG----------LVFTHRPEPSKP------PI 2510 Query: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 A PV P +Q P + P + S +S ++ + + P P + K Sbjct: 2511 APKPVIPQLPTTTQKPTDIHPKPTGL--SLTSSMTLNLVTSADYKLPSPTSPLSPHSNKS 2568 Query: 477 PPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 P+ +L T + LPS P + S S ++ PL +P + L+ V Sbjct: 2569 SPRFSKSLTETYVVITLPSEPGT---PTDSSASQAITSWPLGSP--------SKDLVSVE 2617 Query: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 P P + A P + +SG T + P P Sbjct: 2618 PVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656 Score = 44.3 bits (103), Expect = 5e-04 Identities = 80/349 (22%), Positives = 115/349 (32%), Gaps = 54/349 (15%) Query: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 211 P P P S + P P P P PP P + + + T Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446 Query: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271 SP P + L S+ P++ + P P P PS P GL Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500 Query: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS----APPSLQTLPSPPATPPSQAT 327 P+ + P P++ P+ P+ P+ P L S + A Sbjct: 2501 HRPEPSKP---------PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551 Query: 328 TSLGSPTLQ-ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386 L SPT + HS SP S T + + LP + P P S T P Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRFSKSLT---ETYVVITLP---SEPGTPTDSSASQAITSWP 2605 Query: 387 QAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSP-----SATPPSQAPPSLAAPP- 439 + + ++ FS PP V+ P S + +S SATP + AP S A P Sbjct: 2606 LGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT-APSSFQAAPT 2664 Query: 440 ------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 +V + +P + S+ P PLA + L KP Sbjct: 2665 SVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKP 2713 Score = 41.2 bits (95), Expect = 0.004 Identities = 39/126 (30%), Positives = 48/126 (38%), Gaps = 42/126 (33%) Query: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534 KP Q P +P + +LP+ P PF S+SL +S A PPP PP Sbjct: 2371 KPASQLPSG--SPSVSSLPAKPR------PFFRSSSLDIS--AQPPPPPPP--------- 2411 Query: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594 PP PP PP P P P P PPP+ + L L S Sbjct: 2412 PPPPPP---------PPPPPP--------------PPPLPPPTSPKPTILPKKKLTVASP 2448 Query: 595 SATSTP 600 T+TP Sbjct: 2449 VTTATP 2454 Score = 38.1 bits (87), Expect = 0.033 Identities = 84/363 (23%), Positives = 117/363 (32%), Gaps = 62/363 (17%) Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77 +A+ P P PP P PPPP P + K A + AT A Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461 Query: 78 GPT----RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133 T R++ P + APP P P S P T RP P Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPP--VPPKPSSIPSGLVFTHRPEP-------------- 2505 Query: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGLPRPAPSA 187 K APK + T PT P P + + + LP P Sbjct: 2506 --SKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPL 2561 Query: 188 RPRPPTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246 P PR S S + T PS G +S S + ++ PL SP++ Sbjct: 2562 SPHSNKSSPRFSKSLTETYVVITLPSEP---------GTPTDSSASQAITSWPLGSPSKD 2612 Query: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306 S P P + A+ P + + AL S++P+ PS Sbjct: 2613 LVSVE-----PVFSVVPP---VTAVEIPISSEQTFYISGALQTFSATPVTAPS------- 2657 Query: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366 + + P + TT + + AT S PS LS ++ P P AL L Sbjct: 2658 -------SFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHL 2710 Query: 367 QAP 369 + P Sbjct: 2711 EKP 2713 Score = 34.7 bits (78), Expect = 0.37 Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%) Query: 367 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 421 Q+P A+ P P+P + + A +Q SPP SP V +P SP + Sbjct: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635 Query: 422 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 SA P + P P +P + P PPASP + P PL+ + ++ Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695 Query: 477 PPQAPPALATPPLQALPSPPA 497 P Q T Q + S A Sbjct: 3696 PFQYTEGYTTKGSQTMTSSGA 3716 Score = 33.5 bits (75), Expect = 0.82 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%) Query: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 S SP + SPP P+ + A +Q+ PSPP SP + S P Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631 Query: 462 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519 L + + KP P +P + P + +P S S P+SP A Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691 Query: 520 PPQAP 524 +AP Sbjct: 3692 SSRAP 3696 Score = 32.0 bits (71), Expect = 2.4 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 12/132 (9%) Query: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364 S + P + SPP +G S L + LA PP++P L P Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPTPLEIGYS------SHLRADSTVQLAPSPPKSPKVLYSP 3626 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP----VQAPFSPPASPP 420 P P P P + V PP SP +Q S P P Sbjct: 3627 ISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP--KP 3684 Query: 421 VSPSATPPSQAP 432 +SP+A S+AP Sbjct: 3685 LSPTADESSRAP 3696 >gi|150378539 piccolo isoform 1 [Homo sapiens] Length = 5142 Score = 124 bits (312), Expect = 3e-28 Identities = 155/606 (25%), Positives = 222/606 (36%), Gaps = 97/606 (16%) Query: 31 GSPRPPPPVTPAALRV-LGAAGAVGRKPLA---ERAGGIGGATIPESAPRAG-------- 78 G+ P PA + L R+ +A RA G+ ++P +A + Sbjct: 28 GAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQEL 87 Query: 79 -----PTRTSRPPASGRGERAPPAKNTSPGPVSS----PGRASGT-TRPGPLGQKGLRIS 128 P ++ RPP GR + +K+ + S PGR+ T + + L+ Sbjct: 88 DSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEE 147 Query: 129 AEETVARGKATEAPKRSALSAGARR----DTSGPTPGTPSPAMARRSRAAGTEVGLPR-- 182 + ++ G +E SA+S+ + D + + ++ + E G P Sbjct: 148 HKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEET-TKKQKVVQKEQGKPEGI 206 Query: 183 ---------PAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 233 P P + + P P + + S+ +P + P G +Q P Sbjct: 207 IKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQ 266 Query: 234 SSSAT-PLSSPA-----RSGPSARGTPRAPAHPSQPKPKGLQAL--RPPQVTPPRKDAAP 285 + A PL A + RG P+ PS KP Q +PP P + + P Sbjct: 267 TDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQP 326 Query: 286 ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPAT--PPSQATTSLGSPTLQATHSFLP 343 GP + P A PS P P +++ PP T PP+Q P Q T S P Sbjct: 327 --GP--AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGP-AKPPAQQTGSEKP 381 Query: 344 SPPLSPLATPPPQA---PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400 S P P+A PP + P Q P PA PP + TP P A +AP Sbjct: 382 SSE-----QPGPKALAQPPGVGKTPAQQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKAP 434 Query: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460 P PVQ P P P QA P + P PP+ P A PPP Sbjct: 435 --GPTKTPVQQP---------GPGKIPAQQAGPGKTSAQQTGPTKPPSQLP--GPAKPPP 481 Query: 461 QAPPPLAAPPLQ--LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 518 Q P P PP Q AKPP Q P + PP Q P+ P+ P P +T Sbjct: 482 QQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS--------------PQQPGST 527 Query: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578 PP P A P Q P PA P+ Q +P + T P ++P PPS+ Sbjct: 528 KPPSQQPGSAKPSAQQPS--PAKPSAQQSTKPVS---QTGSGKPLQPPTVSPSAKQPPSQ 582 Query: 579 SPSSTL 584 T+ Sbjct: 583 GLPKTI 588 Score = 113 bits (282), Expect = 8e-25 Identities = 176/718 (24%), Positives = 256/718 (35%), Gaps = 126/718 (17%) Query: 5 RDKAKAGAAARTPAARAPGLLTPRPPGSPRP--PPPVTPAALRVLGAAGAVGRKPLAERA 62 RD + ++ +++ P + +PPG+ +P P TP +P ++A Sbjct: 227 RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQA 286 Query: 63 GGIGGATI------PESAPRAGPTRTSRPPA-------SGRGERAPPAKNTS-------- 101 + G ++ P P PT +PPA S G PPA+ + Sbjct: 287 DIVRGESVKPSLPSPSKPPIQQPT-PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQ 345 Query: 102 PGPVSSPGRASGTTRPG--PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT 159 PG V P + GTT+P PLG + A++T + ++E P AL A+ G T Sbjct: 346 PGTVKPPVQPPGTTKPPAQPLGPA--KPPAQQTGSEKPSSEQPGPKAL---AQPPGVGKT 400 Query: 160 PGT-PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 218 P P PA + +VG P+P +P + P K+ ++ +P P Sbjct: 401 PAQQPGPA-----KPPTQQVGTPKPLAQ---QPGLQSPAKA-PGPTKTPVQQPGPGKIPA 451 Query: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTP 278 AG G + + L PA+ P G + P P QP + +P P Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPP--PQQPGSAKPPSQQPGSTKP 509 Query: 279 PRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQAT 338 P + PA P P +T PS P SA PS Q PSP A P +Q +T S T + Sbjct: 510 PPQQPGPAK-PSPQQPGSTKPPSQQPG-SAKPSAQQ-PSP-AKPSAQQSTKPVSQT--GS 563 Query: 339 HSFLPSPPLSPLATPPP-QAPPALALPPLQAPPSPPASPPLSPLAT-------------- 383 L P +SP A PP Q P P P + T Sbjct: 564 GKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGF 623 Query: 384 -PSPQAP--------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPS 434 P+P N L +P PS P + P + + S + P Sbjct: 624 NPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQ----- 678 Query: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLA------APPLQLAKPPPQ-------AP 481 P Q P A+P S P P+ PPPL P AK PP+ AP Sbjct: 679 ----PQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAP 734 Query: 482 PALATPPLQALPSPPASFPGQAP--FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPP 539 P + P + +P A + P P+ L S AT P P + +PP Sbjct: 735 PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPP 794 Query: 540 ASPTLQAPRR--PPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSAT 597 P + PPT G +++ + P P S S + GP S Sbjct: 795 LKTDSAKPSQSFPPT--------GEKVSPFDSKAIPRPASDSKIISHPGP---SSESKGQ 843 Query: 598 STPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPA 655 + ++ + + SP PDA+ P P +G+P P P P A Sbjct: 844 KQVDPVQKKEEPKKAQTKMSPKPDAK------------PMP----KGSPTPPGPRPTA 885 Score = 108 bits (270), Expect = 2e-23 Identities = 178/746 (23%), Positives = 268/746 (35%), Gaps = 154/746 (20%) Query: 17 PAARAPGLLTP--RPPGSPRPPP-PVTPAALRVLGAAGAVGRKPLAERAG--------GI 65 P A+ PG + P +PPG+ +PP P+ PA A KP +E+ G G+ Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPP---AQQTGSEKPSSEQPGPKALAQPPGV 397 Query: 66 GGATIPESAPRAGPTR---TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG--PL 120 G + P PT+ T +P A G ++P +PGP +P + G PG P Sbjct: 398 GKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK---APGPTKTPVQQPG---PGKIPA 451 Query: 121 GQKGL-RISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 179 Q G + SA++T T+ P S L A+ P P P P ++ + G Sbjct: 452 QQAGPGKTSAQQT----GPTKPP--SQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505 Query: 180 LPRPAPS----ARP--------RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR 227 +P P A+P +PP++ P + SA + S +PS +P + G + Sbjct: 506 STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGK 565 Query: 228 PASRSLSSSATPLSSPARSGPSARGTPRA---------------------PAHPSQPKPK 266 P P SP+ P ++G P+ Q Sbjct: 566 PLQ-------PPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVC 618 Query: 267 GLQALRP-PQVTPPRK--------------DAAPALGP----LSSSPLATPSPSAPPSPS 307 L P P +T ++ D AP L ++P+ T S S S Sbjct: 619 SLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTS---AVSKS 675 Query: 308 APPSLQTLPSPPATPP---SQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364 +P QT P A P S+A P L + SP S A PP+A +L+ P Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSP--SAKAKQPPEA-DSLSKP 732 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNAL-----AVHLLQAPFSPP-PSPPVQAPFSPPAS 418 PS P+ +P+A P+ P + V A P PS VQ+ + Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792 Query: 419 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPP 478 PP+ + PSQ+ PP+ P A P P + + + P P Sbjct: 793 PPLKTDSAKPSQS----------FPPTGEKVSPFDSKAIPRPASDSKIISHP----GPSS 838 Query: 479 QAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSP 538 ++ P+Q P + Q SP P +P P P P Sbjct: 839 ESKGQKQVDPVQKKEEPKKA---QTKMSPKPDAKPMPKGSPTPPG------------PRP 883 Query: 539 PASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR--SPSSTLSGPDLAGHSSSA 596 A T+ P++ P P + R +L L P S+ +P T++G L G +S Sbjct: 884 TAGQTVPTPQQSPKPQEQSR----RFSLNLGSITDAPKSQPTTPQETVTG-KLFGFGASI 938 Query: 597 TSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPAT 656 S L A P P ++ P + P+ P +G P + PPA Sbjct: 939 FSQASNLI--------STAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPA- 989 Query: 657 GPGSADGLCTIYETEGPESATPAPGA 682 A + ET+ P + P A Sbjct: 990 ---PAKSIPVKKETKAPAAEKLEPKA 1012 Score = 108 bits (269), Expect = 3e-23 Identities = 188/766 (24%), Positives = 264/766 (34%), Gaps = 132/766 (17%) Query: 28 RPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT-SRPP 86 +PP +PP P+ GR PL + P+S P + S+PP Sbjct: 208 KPPLQQQPPKPIPKQQ--------GPGRDPLQQDG-------TPKSISSQQPEKIKSQPP 252 Query: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQKGLRISAEET-VARGKATEAPKR 144 +G+ P+ P + T PL + R ++ + RG++ + Sbjct: 253 GTGK-------------PIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV----K 295 Query: 145 SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA-----PSARPRPPTEGPRKS 199 +L + ++ PTPG P ++ G E P PA PS +P + P Sbjct: 296 PSLPSPSKPPIQQPTPGKPP------AQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTV 349 Query: 200 VSSASEHSTTEP--SPAARRRPSAGG-GLQRPASRSLSSSATPLSSPARSGPSARGTPRA 256 TT+P P +P A G ++P+S A L+ P P TP Sbjct: 350 KPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKA--LAQP----PGVGKTPAQ 403 Query: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLP 316 P++P + + +P P + A A GP + +P+ P P P+ A P + Sbjct: 404 QPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGP-TKTPVQQPGPGKIPAQQAGPGKTSAQ 462 Query: 317 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 376 T P P Q P P A PP Q P + PP Q P+ P+ Sbjct: 463 QTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS-- 520 Query: 377 PLSPLATPSPQAPNALAVHLLQAPFSPPPS------PPVQAPFSPPASPP-VSPSA-TPP 428 P P +T P A Q P PS P Q P PP VSPSA PP Sbjct: 521 PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580 Query: 429 SQAPPSLAAP-------PLQVPPSPPASPPMSPSAT--------PPPQAP---------- 463 SQ P P L VP + T P P Sbjct: 581 SQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC 640 Query: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA-SLPMSPL--ATPP 520 A LA P P L T P+ + S P SP + P L A P Sbjct: 641 QMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEP 700 Query: 521 PQAPPVLAAPLLQVPPS-----PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 575 + PP++ P L PS PP + +L P P P SV + +A P Sbjct: 701 KKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEP----SVPSEQDKAPVADDKPKQ 756 Query: 576 PSR--------SPSSTLSGPDLAG---HSSSATSTPEELRGYDSGPEGGAAASPPPDAEL 624 P S SS + PD+ S + T L+ + P + S PP E Sbjct: 757 PKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP----SQSFPPTGEK 812 Query: 625 AACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA----TPAP 680 + + PA PG P + G D + + E P+ A +P P Sbjct: 813 VSPFDSKAIPRPASDSKIISHPG---PSSESKGQKQVD---PVQKKEEPKKAQTKMSPKP 866 Query: 681 GALD-PGPSPGTSGGKAAAGAGAGASSRSPK---QARLGELPLGAL 722 A P SP G + AG +SPK Q+R L LG++ Sbjct: 867 DAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912 Score = 105 bits (262), Expect = 2e-22 Identities = 108/408 (26%), Positives = 146/408 (35%), Gaps = 49/408 (12%) Query: 199 SVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPA 258 S S AS+ TT+ ++ G+ +P + P + P +G R P Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQ---------QPPKPIPKQQGPGRDPL 230 Query: 259 HPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSP 318 PK + + +P ++ K P G P TP P LQ S Sbjct: 231 Q-QDGTPKSISSQQPEKI----KSQPPGTGKPIQGPTQTPQTDHAKLP-----LQRDASR 280 Query: 319 PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPL 378 P T QA G ++ LPSP P+ P P PPA ++ P P A PP Sbjct: 281 PQT--KQADIVRG----ESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGP-AKPPA 333 Query: 379 SP--LATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA 436 P L P Q P + + + PP+ P+ P PPA S + P +LA Sbjct: 334 QPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPL-GPAKPPAQQTGSEKPSSEQPGPKALA 392 Query: 437 APPLQVPPSP-----PASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALATPP 488 PP V +P PA PP TP P A P P + P P Q P P Sbjct: 393 QPP-GVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPA 451 Query: 489 LQALPS-----------PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS 537 QA P PP+ PG A P P P P A P P PP Sbjct: 452 QQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPP 511 Query: 538 PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585 P +P++P + P + G A P P P ++ + +S Sbjct: 512 QQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVS 559 Score = 99.4 bits (246), Expect = 1e-20 Identities = 141/590 (23%), Positives = 192/590 (32%), Gaps = 82/590 (13%) Query: 167 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 226 +A + A G G P+ +A P G +S SE + + R G Sbjct: 16 LAAAAAAGGGASGAGSPSHTAIPA----GMEADLSQLSEEERRQIAAVMSRAQGLPKGSV 71 Query: 227 RPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP---KPKGLQALRPPQVTPPRKDA 283 PA+ S + P G P P P+QP K + R Q P R Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGR--- 128 Query: 284 APALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLP 343 +P+ L S T S P L + + A + + S Sbjct: 129 SPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEASQEE 188 Query: 344 SPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ--APNALAVHLLQAPF 401 + + P + PPLQ P P P P Q P +++ + Sbjct: 189 TTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIK 248 Query: 402 SPPPSP--PVQAPFSPP----ASPPVSPSATPPSQAP-------------PSLAAPPLQ- 441 S PP P+Q P P A P+ A+ P PS + PP+Q Sbjct: 249 SQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQ 308 Query: 442 -VPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP---------PPQAPPALATPPLQA 491 P PPA P + P P PP A P L KP PP PP PP Q Sbjct: 309 PTPGKPPAQQPGHEKSQPGPAKPP---AQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQP 365 Query: 492 L--PSPPASFPGQAPFSPSASLPMSPLATPPP-------QAPPVLAAPLLQV-PPSPPAS 541 L PPA G PS+ P PP Q P P QV P P A Sbjct: 366 LGPAKPPAQQTGSE--KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQ 423 Query: 542 -PTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD-LAGHSSSATST 599 P LQ+P + P GP T PGP P++ +GP + + T Sbjct: 424 QPGLQSPAKAP---------GPTKTPVQQPGPGKIPAQQ-----AGPGKTSAQQTGPTKP 469 Query: 600 PEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG 659 P +L G P + PP + + P + G P + P P P P + Sbjct: 470 PSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGS--- 526 Query: 660 SADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSP 709 T ++ P SA P+ P K + G+G + P Sbjct: 527 ------TKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPP 570 Score = 80.5 bits (197), Expect = 6e-15 Identities = 135/617 (21%), Positives = 206/617 (33%), Gaps = 86/617 (13%) Query: 4 KRDKAKAGAAARTPAARAPGLLTPRPPGSPRPPP----PVTPAALRVLGA--AGAVGRKP 57 K + G+ P P +P+ PGS +PP P+A + A + KP Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557 Query: 58 LAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRP 117 +++ G P P P+ +PP+ G + P NT+ + P +A+ T Sbjct: 558 VSQTGSG-----KPLQPPTVSPS-AKQPPSQGLPKTICPLCNTTELLLHVPEKANFNT-- 609 Query: 118 GPLGQKGLRISAEETVA-------RGKATEAPKRSALSAGARRDTSG---PTPGTPSPAM 167 + TV TE + L+ +R G P P +P P + Sbjct: 610 --------CTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661 Query: 168 ARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEP---SPAARRRPSAGGG 224 + V P P P++ +S A E P P PSA Sbjct: 662 KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA-KA 720 Query: 225 LQRPASRSLSSSATP----LSSPARSGPSARGTPRAP--AHPSQPKPKGLQALRPPQV-- 276 Q P + SLS A P + S P A P+ P P+ A P + Sbjct: 721 KQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPS 780 Query: 277 TPPRKDAAPALGPLSSSPLATPSPSAPPSPS--APPSLQTLPSPPA-----TPPSQATTS 329 + + A P + A PS S PP+ +P + +P P + + P ++ S Sbjct: 781 SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSES 840 Query: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389 G + +P P A P +P + P+PP P + P+PQ Sbjct: 841 KGQKQVDPVQKKEEPKKAQTKMSPKPDAKP---MP--KGSPTPPGPRPTAGQTVPTPQ-- 893 Query: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449 Q+P S P S TP L + AS Sbjct: 894 --------QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASI--FSQAS 943 Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPL---QALPSPPASFPGQAPFS 506 +S + P P + AP Q P P PP PP QA P+P S P + Sbjct: 944 NLISTAGQPGPHSQSGPGAPMKQ--APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK 1001 Query: 507 PSASLPMSPLATPPP---------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT 557 A+ + P A P + PP+ + L P PT + +P P++ Sbjct: 1002 APAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVLPT----KLEKSPKPES 1057 Query: 558 SVSGPRLTLALAPGPPP 574 + + L + PP Sbjct: 1058 TCPLCKTELNIGSKDPP 1074 Score = 61.6 bits (148), Expect = 3e-09 Identities = 80/310 (25%), Positives = 117/310 (37%), Gaps = 49/310 (15%) Query: 306 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365 PS PS+ +LP+ P P ++SL S P PP P PPP PP Sbjct: 2377 PSGSPSVSSLPAKPR--PFFRSSSLDI-------SAQPPPPPPPPPPPPPPPPP------ 2421 Query: 366 LQAPPSPPASPPLSPLATPSPQ------APNALAVHLLQAPFSPPPSPPVQAPFSP---- 415 PP PP PP SP T P+ +P A L A + + +++ P Sbjct: 2422 ---PPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRI 2478 Query: 416 --PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAPPPLAAPPLQ 472 A PPV P PS P L P PP +P P+ P Q P + P Sbjct: 2479 CTTAPPPVPPK---PSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTG 2535 Query: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL 532 L+ L T LPSP +P SP ++ + P + + ++ Sbjct: 2536 LSLTSSMT-LNLVTSADYKLPSP------TSPLSPHSN------KSSPRFSKSLTETYVV 2582 Query: 533 QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLA 590 PS P +PT + + T P S S +++ + PP P S+ ++ Sbjct: 2583 ITLPSEPGTPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYIS 2642 Query: 591 GHSSSATSTP 600 G + ++TP Sbjct: 2643 GALQTFSATP 2652 Score = 59.7 bits (143), Expect = 1e-08 Identities = 62/211 (29%), Positives = 79/211 (37%), Gaps = 30/211 (14%) Query: 416 PAS--PPVSPSATP-PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQ 472 PAS P SPS + P++ P + L + PP PP P PPP PPP PP Sbjct: 2372 PASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPT 2431 Query: 473 LAKPP--PQAPPALATPPLQALPSPPA-SFPGQAPFSPSASLPMSPLAT--PPPQAPPVL 527 KP P+ +A+P A P A + S LP++ + T PPP P Sbjct: 2432 SPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPS 2491 Query: 528 AAPLLQV------PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG---------- 571 + P V P PP +P P+ P T T + L+L Sbjct: 2492 SIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551 Query: 572 ---PPPPPSRSPSSTLSGPDLAGHSSSATST 599 P P SP S S P S S T T Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRF---SKSLTET 2579 Score = 59.3 bits (142), Expect = 1e-08 Identities = 85/361 (23%), Positives = 129/361 (35%), Gaps = 68/361 (18%) Query: 224 GLQRPASRSLSSSATPLSSPARSGP---------SARGTPRAPAHPSQPKPKGLQALRPP 274 G ++PAS+ S S + S PA+ P SA+ P P P P P PP Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPP---PPPPPP 2424 Query: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334 PP P + P +A+P +A P A +L+T T L S Sbjct: 2425 PPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLET------------TAVLRSNG 2472 Query: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP-PLSPLATPSPQAP---- 389 L T +PP P+ P P L P PP +P P+ P + Q P Sbjct: 2473 LPVTRICTTAPP--PVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIH 2530 Query: 390 ---------NALAVHLLQAPFSPPPSPPVQ-APFSPPASPPVSPSAT--------PPSQA 431 +++ ++L+ + PSP +P S +SP S S T P Sbjct: 2531 PKPTGLSLTSSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPG 2590 Query: 432 PPSLAAPPLQVPPSPPASPPMS-PSATPPPQAPPPLAAPPLQLAKPPP----------QA 480 P+ ++ + P SP S P PP+ A + ++ A Sbjct: 2591 TPTDSSASQAITSWPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSA 2650 Query: 481 PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPV-LAAPLLQVPPSPP 539 P A QA P+ F + + + ++ AP V L++ + +PP P Sbjct: 2651 TPVTAPSSFQAAPTSVTQF-------LTTEVSKTEVSATRSTAPSVGLSSISITIPPEPL 2703 Query: 540 A 540 A Sbjct: 2704 A 2704 Score = 53.5 bits (127), Expect = 8e-07 Identities = 81/339 (23%), Positives = 114/339 (33%), Gaps = 61/339 (17%) Query: 243 PARSGPSARGTPRAPAHPSQPKP------KGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296 PA PS G+P + P++P+P + A PP PP Sbjct: 2372 PASQLPS--GSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP----------------- 2412 Query: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQ 356 P P PP P PP L SP T + ++ SP AT F L A Sbjct: 2413 -PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSN 2471 Query: 357 APPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPP 416 P + PP PP P + PS L P PS P P Sbjct: 2472 GLPVTRICTTAPPPVPP-----KPSSIPSG----------LVFTHRPEPSKP------PI 2510 Query: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 A PV P +Q P + P + S +S ++ + + P P + K Sbjct: 2511 APKPVIPQLPTTTQKPTDIHPKPTGL--SLTSSMTLNLVTSADYKLPSPTSPLSPHSNKS 2568 Query: 477 PPQAPPALA-TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 535 P+ +L T + LPS P + S S ++ PL +P + L+ V Sbjct: 2569 SPRFSKSLTETYVVITLPSEPGT---PTDSSASQAITSWPLGSP--------SKDLVSVE 2617 Query: 536 PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574 P P + A P + +SG T + P P Sbjct: 2618 PVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAP 2656 Score = 44.3 bits (103), Expect = 5e-04 Identities = 80/349 (22%), Positives = 115/349 (32%), Gaps = 54/349 (15%) Query: 160 PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS--------EHSTTEP 211 P P P S + P P P P PP P + + + T Sbjct: 2387 PAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVA 2446 Query: 212 SPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL 271 SP P + L S+ P++ + P P P PS P GL Sbjct: 2447 SPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP-----PPVPPKPSS-IPSGLVFT 2500 Query: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS----APPSLQTLPSPPATPPSQAT 327 P+ + P P++ P+ P+ P+ P L S + A Sbjct: 2501 HRPEPSKP---------PIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSAD 2551 Query: 328 TSLGSPTLQ-ATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386 L SPT + HS SP S T + + LP + P P S T P Sbjct: 2552 YKLPSPTSPLSPHSNKSSPRFSKSLT---ETYVVITLP---SEPGTPTDSSASQAITSWP 2605 Query: 387 QAPNALAVHLLQAPFS-PPPSPPVQAPFSPPASPPVSP-----SATPPSQAPPSLAAPP- 439 + + ++ FS PP V+ P S + +S SATP + AP S A P Sbjct: 2606 LGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVT-APSSFQAAPT 2664 Query: 440 ------------LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 +V + +P + S+ P PLA + L KP Sbjct: 2665 SVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHLEKP 2713 Score = 41.2 bits (95), Expect = 0.004 Identities = 39/126 (30%), Positives = 48/126 (38%), Gaps = 42/126 (33%) Query: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534 KP Q P +P + +LP+ P PF S+SL +S A PPP PP Sbjct: 2371 KPASQLPSG--SPSVSSLPAKPR------PFFRSSSLDIS--AQPPPPPPP--------- 2411 Query: 535 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 594 PP PP PP P P P P PPP+ + L L S Sbjct: 2412 PPPPPP---------PPPPPP--------------PPPLPPPTSPKPTILPKKKLTVASP 2448 Query: 595 SATSTP 600 T+TP Sbjct: 2449 VTTATP 2454 Score = 38.1 bits (87), Expect = 0.033 Identities = 84/363 (23%), Positives = 117/363 (32%), Gaps = 62/363 (17%) Query: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77 +A+ P P PP P PPPP P + K A + AT A Sbjct: 2402 SAQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTT 2461 Query: 78 GPT----RTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133 T R++ P + APP P P S P T RP P Sbjct: 2462 LETTAVLRSNGLPVTRICTTAPPP--VPPKPSSIPSGLVFTHRPEP-------------- 2505 Query: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSP------AMARRSRAAGTEVGLPRPAPSA 187 K APK + T PT P P + + + LP P Sbjct: 2506 --SKPPIAPK--PVIPQLPTTTQKPTDIHPKPTGLSLTSSMTLNLVTSADYKLPSPTSPL 2561 Query: 188 RPRPPTEGPRKSVSSASEHST-TEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARS 246 P PR S S + T PS G +S S + ++ PL SP++ Sbjct: 2562 SPHSNKSSPRFSKSLTETYVVITLPSEP---------GTPTDSSASQAITSWPLGSPSKD 2612 Query: 247 GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSP 306 S P P + A+ P + + AL S++P+ PS Sbjct: 2613 LVSVE-----PVFSVVPP---VTAVEIPISSEQTFYISGALQTFSATPVTAPS------- 2657 Query: 307 SAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL 366 + + P + TT + + AT S PS LS ++ P P AL L Sbjct: 2658 -------SFQAAPTSVTQFLTTEVSKTEVSATRSTAPSVGLSSISITIPPEPLALDNIHL 2710 Query: 367 QAP 369 + P Sbjct: 2711 EKP 2713 Score = 34.7 bits (78), Expect = 0.37 Identities = 38/141 (26%), Positives = 55/141 (39%), Gaps = 10/141 (7%) Query: 367 QAPPSPPASPPLSPLATPSP----QAPNALAVHLLQAPFSPPPSPPV-QAPFSPPASPPV 421 Q+P A+ P P+P + + A +Q SPP SP V +P SP + Sbjct: 3576 QSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLSPGKA 3635 Query: 422 SPSATPPSQAP-PSLAAPPLQVPPS----PPASPPMSPSATPPPQAPPPLAAPPLQLAKP 476 SA P + P P +P + P PPASP + P PL+ + ++ Sbjct: 3636 LESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRA 3695 Query: 477 PPQAPPALATPPLQALPSPPA 497 P Q T Q + S A Sbjct: 3696 PFQYTEGYTTKGSQTMTSSGA 3716 Score = 33.5 bits (75), Expect = 0.82 Identities = 32/125 (25%), Positives = 46/125 (36%), Gaps = 3/125 (2%) Query: 402 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 461 S SP + SPP P+ + A +Q+ PSPP SP + S P Sbjct: 3573 SDTQSPQYLSATSPPKDKK-RPTPLEIGYSSHLRADSTVQLAPSPPKSPKVLYSPISPLS 3631 Query: 462 APPPLAAPPLQLAKPPPQ--APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519 L + + KP P +P + P + +P S S P+SP A Sbjct: 3632 PGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADE 3691 Query: 520 PPQAP 524 +AP Sbjct: 3692 SSRAP 3696 Score = 32.0 bits (71), Expect = 2.4 Identities = 34/132 (25%), Positives = 45/132 (34%), Gaps = 12/132 (9%) Query: 305 SPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 364 S + P + SPP +G S L + LA PP++P L P Sbjct: 3573 SDTQSPQYLSATSPPKDKKRPTPLEIGYS------SHLRADSTVQLAPSPPKSPKVLYSP 3626 Query: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP----VQAPFSPPASPP 420 P P P P + V PP SP +Q S P P Sbjct: 3627 ISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDP--KP 3684 Query: 421 VSPSATPPSQAP 432 +SP+A S+AP Sbjct: 3685 LSPTADESSRAP 3696 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 124 bits (311), Expect = 4e-28 Identities = 207/833 (24%), Positives = 258/833 (30%), Gaps = 157/833 (18%) Query: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPV-----------------TPAALRVLGA 49 + AG R PGL P PPG P PP P + + V G Sbjct: 123 RGPAGPPGRDGIPGQPGL--PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGP 180 Query: 50 AGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASG----RGERAPPAKNTSPGPV 105 G G + L G GA P+ + P P ASG RG PP KN G Sbjct: 181 MGPSGPRGLP----GPPGAPGPQGF-QGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEA 235 Query: 106 SSPGRASGTTRPGPLGQKGLRISAEETVARG----KATEAPKRSALSAGARRDTSGP--- 158 PGR PGP G +GL +A +G + K A AG + + P Sbjct: 236 GKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGEN 295 Query: 159 ----------------TPGTPSPAMARRSRAAGTEVGLPRP-----------APSARPRP 191 PG P PA AR + A G P P A A+ Sbjct: 296 GAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEA 355 Query: 192 PTEGPRKSVSSASEHSTT-EPSPAARRRPSAGGGLQ-RPASRSLSSSATPLSSPARSGPS 249 +GPR S P PA P+ G +P ++ + + +P G Sbjct: 356 GPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAP 309 P+ P P P PKG P K A G P+ P P Sbjct: 416 GPSGPQGPGGP--PGPKGNSG---EPGAPGSKGDTGAKG--EPGPVGVQGPPGPAGEEGK 468 Query: 310 PSLQTLPSPPAT--PPSQ--ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA----- 360 + P P PP + S G P P P +P P P Sbjct: 469 RGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAG--PKGPAGERGSPGPAGPKGSPGEA 526 Query: 361 -----LALPPLQAPPSPPASP-PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414 LP + P SP P P P + PP P + Sbjct: 527 GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRP--------GPPGPPGARGQAG 578 Query: 415 PPASPPVSPSATPPSQA-------PPSLAAPP-------LQVPPSP--PASP--PMSPSA 456 P +A P +A PP P Q PP P PA P+ Sbjct: 579 VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG 638 Query: 457 TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFS--PSASLPMS 514 +P Q P A PP + KP Q P P + FPG+ P + P Sbjct: 639 SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRG 698 Query: 515 PLATP----------PPQAPPVLAAPLLQVPPSPPASPTLQAPR----------RPPTPG 554 P P AP AP LQ P + L P+ +PG Sbjct: 699 ANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPG 758 Query: 555 PD--TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612 D ++GP GPP P SGP + A P + RG + GP G Sbjct: 759 KDGVRGLTGP-------IGPPGPAGAPGDKGESGPSGPAGPTGARGAPGD-RG-EPGPPG 809 Query: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG-----SADGLCTI 667 A + PP A+ P A +G +G G P P PA PG A G Sbjct: 810 PAGFAGPPGAD---GQPGA--KGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGA 864 Query: 668 YETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLG 720 + GP AT PGA PG SG G A K R P G Sbjct: 865 RGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAG 917 Score = 118 bits (295), Expect = 3e-26 Identities = 213/812 (26%), Positives = 256/812 (31%), Gaps = 143/812 (17%) Query: 21 APGLLTPRP-PGSPRPPPPVTPAALR----VLGAAGAVGRKPLAERAGGIGGATIPESAP 75 APG + PR PG P PA R GAAG G A G G A Sbjct: 297 APGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG 356 Query: 76 RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVAR 135 GP R S P RGE PP + GP +PG G G G+ + AR Sbjct: 357 PQGP-RGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGAR 415 Query: 136 GKA-------TEAPKRSALSAGA---RRDTSG---PTP----GTPSPAMARRSRAAGTE- 177 G + PK ++ GA + DT P P G P PA R A E Sbjct: 416 GPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEP 475 Query: 178 --VGLPRP-----APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 230 GLP P P +R P +G A E + P PA + G RP Sbjct: 476 GPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS--PGPAGPKGSPGEAG--RPGE 531 Query: 231 RSLSSSATPLSSPARSGPSARGTPRAPA----HPSQPKPKGLQALRPPQVTPPRKDAAP- 285 L + SP GP + P PA P P P G + P K AA Sbjct: 532 AGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGE 591 Query: 286 --------------ALGPLSSSPLA----TPSPSAPPS------PSAPPSLQTLPSPPAT 321 A+GP A P P+ P P+ P Q LP P A Sbjct: 592 PGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGP-AG 650 Query: 322 PPSQATT--------SLGSPTLQATHSFLPSPPLSPLATPP------------------- 354 PP +A LG+P P + PP Sbjct: 651 PPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKG 710 Query: 355 ----PQAPPALALPPLQAPPSPPASP----PLSPLATPSPQ----APNALAVHLLQAPFS 402 P AP + P LQ P + P P+ +P V L P Sbjct: 711 DAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG 770 Query: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 462 PP P AP S P P+ ++ P P P+ A PP + P Sbjct: 771 PPG--PAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQ--PGAK 826 Query: 463 PPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQ 522 P A A PP A PA P+ + +P A + P A+ P Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPP 886 Query: 523 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS 582 P A P PP P + PR P GP PGPP P S Sbjct: 887 GPSGNAGP--PGPPGPAGKEGGKGPRGETGPAGRPGEVGP-------PGPPGPAGEKGSP 937 Query: 583 TLSGPDLAGHSSSATSTPEELRGYDS-----GPEG--GAAASPPPDAELAACHP--AAWS 633 GP AG + T P+ + G G G G P P E P A+ Sbjct: 938 GADGP--AG--APGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993 Query: 634 RGPAPPLA------------FRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681 RGP P+ GAPGA P G A G GP A APG Sbjct: 994 RGPPGPMGPPGLAGPPGESGREGAPGAEGS-PGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052 Query: 682 ALDPGPSPGTSGGKAAAGAGAGASSRSPKQAR 713 A P G SG + G A P AR Sbjct: 1053 APGPVGPAGKSGDRGETGPAGPAGPVGPVGAR 1084 Score = 104 bits (260), Expect = 3e-22 Identities = 195/757 (25%), Positives = 234/757 (30%), Gaps = 118/757 (15%) Query: 27 PRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAG-PTRTSR 84 P P G P PP P + GA G G K A G G A S AG P Sbjct: 475 PGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL 534 Query: 85 PPASGR----GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 140 P A G G P K PGP GR PG GQ G+ A G+ + Sbjct: 535 PGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGK 594 Query: 141 APKRSALS-----AGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG 195 A +R A +D G P PA R E G P +P + P G Sbjct: 595 AGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERG---EQG-PAGSPGFQGLPGPAG 650 Query: 196 PRKSVSSASEHSTTEPSPAARRRPSAGGGLQR-PASRSLSSSATPLSSPARSGP----SA 250 P E P PS G + P R + P +G A Sbjct: 651 PPGEAGKPGEQGV--PGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGA 708 Query: 251 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS----------- 299 +G AP P GLQ + P + AA GP A P Sbjct: 709 KGDAGAPGAPGSQGAPGLQGM------PGERGAAGLPGPKGDRGDAGPKGADGSPGKDGV 762 Query: 300 -----PSAPPSPSAPPSL--QTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352 P PP P+ P ++ PS PA P T + G+P + P PP Sbjct: 763 RGLTGPIGPPGPAGAPGDKGESGPSGPAGP----TGARGAPGDRGE----PGPPGPAGFA 814 Query: 353 PPPQAP--PALALPPLQAPPSPPASPP--LSPLATPSP----QAPNALAVHLLQAPFSPP 404 PP A P P A A PP P P P AP A P Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGAT 874 Query: 405 PSPPVQAPFSPP-----ASPPVSPSAT-------PPSQAPPSLAAPPLQV-PPSPP--AS 449 P PP A PP P P + P A P +V PP PP A Sbjct: 875 GFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP--AGRPGEVGPPGPPGPAG 932 Query: 450 PPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSA 509 SP A P AP + + P LP P Q P S Sbjct: 933 EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASG 992 Query: 510 SL-PMSPLATPPPQAPPVLA----APLLQVPPSPPASPTLQAPRRPPTP-GPDTSVSGPR 563 P P+ P PP + AP + P SP + R P GP + P Sbjct: 993 ERGPPGPMGPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPG 1052 Query: 564 LTLALAPGPPPPPSRSPSSTLSGP-----DLAGHSSSATSTPEELRGYDSGPEG------ 612 APGP P +S +GP + + + P+ RG D G G Sbjct: 1053 -----APGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRG-DKGETGEQGDRG 1106 Query: 613 --------GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGL 664 G P P P+ S GPA P G+ GAP G +GL Sbjct: 1107 IKGHRGFSGLQGPPGPPGSPGEQGPSGAS-GPAGPRGPPGSAGAP-------GKDGLNGL 1158 Query: 665 CTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 701 GP T G + P PG G AG Sbjct: 1159 PGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSAG 1195 Score = 96.3 bits (238), Expect = 1e-19 Identities = 179/731 (24%), Positives = 214/731 (29%), Gaps = 185/731 (25%) Query: 11 GAAARTPAARAPGLLTPRPPGSP-----RPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65 GA T + +PG P P RP PP P A G G G K A G Sbjct: 536 GAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKA 595 Query: 66 GGATIPESAPRAGPTRTSRP-----------PASGRGERAP---PAKNTSPGPVSSPGRA 111 G +P GP PA RGE+ P P PGP PG A Sbjct: 596 GERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEA 655 Query: 112 SGTTR---------PGPLGQKGLRISAEETVARGKATEAPKRSALSA----GARRDTSGP 158 PGP G +G R E +G A R A A GA+ D P Sbjct: 656 GKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAP 715 Query: 159 -TPGTPSPAMARRSRAAGTEVGLPRPAPS---ARPRPPTEGPRKSVSSASEHSTTEPSPA 214 PG+ + GLP P A P+ P K P PA Sbjct: 716 GAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPA 775 Query: 215 ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS-ARGTPRAPAHPSQPKPKGLQALRP 273 G PA GP+ ARG P P P P G Sbjct: 776 GAPGDKGESGPSGPA-----------------GPTGARGAPGDRGEPGPPGPAGFAG--- 815 Query: 274 PQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSP 333 PP D P P + + PP P+ PA PP ++G+P Sbjct: 816 ----PPGADGQPGAK-------GEPGDAGAKGDAGPPG----PAGPAGPPGPIG-NVGAP 859 Query: 334 TLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALA 393 + P AT P A + P PP P P + P Sbjct: 860 GAKGARGSAGPPG----ATGFPGAAGRVGPPGPSGNAGPPGPP--GPAGKEGGKGPRGET 913 Query: 394 VHLLQAPFSPPPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAA--------------- 437 + PP PP P SP P+ P + P +A Sbjct: 914 GPAGRPGEVGPPGPP--GPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERG 971 Query: 438 -PPLQVPPSPPASPPMSPSA----TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 492 P L P P S ++ P P PP LA PP + + AP A +P Sbjct: 972 FPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREG--APGAEGSPGRDGS 1029 Query: 493 PSP--------PASFPGQAPFSPSASLPMSPLATPP------PQAPPVLAAPL------- 531 P PA PG AP +P A P+ P P P P+ Sbjct: 1030 PGAKGDRGETGPAGPPG-APGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG 1088 Query: 532 ---------------------------LQVPPSPPASPTLQ---------APRRPP---- 551 LQ PP PP SP Q PR PP Sbjct: 1089 PQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAG 1148 Query: 552 TPGPD--------TSVSGPRLTLALA-----PGPPPPPSRSPSSTLSGPDLAGHSSSATS 598 PG D GPR A PGPP PP GP AG S Sbjct: 1149 APGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGP------PGPPSAGFDFSFLP 1202 Query: 599 TPEELRGYDSG 609 P + + +D G Sbjct: 1203 QPPQEKAHDGG 1213 Score = 90.5 bits (223), Expect = 6e-18 Identities = 192/805 (23%), Positives = 235/805 (29%), Gaps = 165/805 (20%) Query: 86 PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG-----LRISAEETVARGKATE 140 P RG PP ++ PG PG PGP G G L +E G + Sbjct: 119 PRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVP 178 Query: 141 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSV 200 P + R GP PG P P + + E G P + PR P P K+ Sbjct: 179 GP----MGPSGPRGLPGP-PGAPGP---QGFQGPPGEPGEPGASGPMGPRGPPGPPGKNG 230 Query: 201 SSASEHSTTEPSPAARRRPSAGGGLQRPA----------------SRSLSSSATPLSSPA 244 P P GL A ++ + A P P Sbjct: 231 DDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPG 290 Query: 245 RSGPSA-------RGTPRAPAHPSQPKPKGLQ-------ALRPPQVTPPRKDAAPALGPL 290 G + RG P P P P G + A PP T P A P P Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGP---AGPPGFPG 347 Query: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350 + P P P ++ P PP P+ A G+P P + Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPPG--PAGAAGPAGNPGAD-------GQPGAKG 398 Query: 351 ATPPPQAPPALALPPLQAPPSP--PASPPLSPLATPSPQAPNALAVHLLQAPFSP----- 403 A P A P + P P P PP + P AP + + P Sbjct: 399 ANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQG 458 Query: 404 PPSPPVQ----------APFSPPASP-------------------PVSPSATPPSQAPPS 434 PP P + P P P P P+ S P Sbjct: 459 PPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAG 518 Query: 435 LAAPPLQVPPSPPASPPMSPSATPPPQAPPP-----LAAPPLQLAKPPPQAPP-ALATPP 488 P + A P + T P +P P P Q +P P PP A Sbjct: 519 PKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578 Query: 489 LQALPSP--PASFPGQA-----PFSPSASLPMSPLATPPPQAPPVLAAPL----LQVPPS 537 + P P A PG+A P P A P Q PP A P Q P Sbjct: 579 VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAG 638 Query: 538 PPASPTLQAPRRPP----------------TPGPDTSVSGPRLTLAL-----APGPPPPP 576 P L P PP PGP SG R GPP P Sbjct: 639 SPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGP----SGARGERGFPGERGVQGPPGPA 694 Query: 577 SRSPSSTLSGPDLAGHSSSATSTP--EELRGYDSGP-EGGAAASPPPDAELAACHPAAWS 633 ++ G D A + A P + G P E GAA P P + P Sbjct: 695 GPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGAD 754 Query: 634 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGAL-DPGP----- 687 P RG G P PA PG G GP A APG +PGP Sbjct: 755 GSPGKD-GVRGLTGPIGPPGPAGAPGD-KGESGPSGPAGPTGARGAPGDRGEPGPPGPAG 812 Query: 688 ---------SPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLA 738 PG G AGA A P P+G + A + Sbjct: 813 FAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAK---------- 862 Query: 739 AAEGAAG--GSGGGPGGAEGGGVTG 761 A G+AG G+ G PG A G G Sbjct: 863 GARGSAGPPGATGFPGAAGRVGPPG 887 Score = 87.4 bits (215), Expect = 5e-17 Identities = 128/505 (25%), Positives = 158/505 (31%), Gaps = 88/505 (17%) Query: 234 SSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSS 293 S S T + GP PR P P+ PP +D P L Sbjct: 99 SESPTDQETTGVEGPKGDTGPRGPRGPA---------------GPPGRDGIPGQPGL--- 140 Query: 294 PLATPSPSAPPSPSAPPSLQTLPSPPAT----PPSQATTSLGSPTLQATHSFLPSPPLSP 349 P P PP P PP L +P + S S+ P + LP PP +P Sbjct: 141 ----PGPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAP 196 Query: 350 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409 P PP + P P AS P+ P P P N P P Sbjct: 197 -------GPQGFQGPPGE-PGEPGASGPMGPRGPPGPPGKNG-----DDGEAGKPGRPGE 243 Query: 410 QAPFSPPASPPVSPSATPPS----QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465 + P P + + +A P + L P+ P P SP P P Sbjct: 244 RGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGP 303 Query: 466 LAAPPLQLAKPPPQAP---------PALATPPLQALPSPPASFPGQAPFSPSASLPMSPL 516 P + +P P A PP P+ P FPG A P P Sbjct: 304 RGLPG-ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAG-PQGPR 361 Query: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPP 576 + PQ ++ P PP P P G +A P P Sbjct: 362 GSEGPQG--------VRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPG 413 Query: 577 SRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGP 636 +R P SGP G E S + GA P P GP Sbjct: 414 ARGP----SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVG-------VQGPPGP 462 Query: 637 APPLAFRGAPGAP----LPWPPAT--GPGS-----ADGLCTIYETEGPESATPAPGALDP 685 A RGA G P LP PP GPGS ADG + +GP +PG P Sbjct: 463 AGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADG---VAGPKGPAGERGSPGPAGP 519 Query: 686 GPSPGTSGGKAAAG-AGAGASSRSP 709 SPG +G AG GA + SP Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSP 544 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.307 0.127 0.388 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 55,582,195 Number of Sequences: 37866 Number of extensions: 4871262 Number of successful extensions: 182942 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 2044 Number of HSP's successfully gapped in prelim test: 3569 Number of HSP's that attempted gapping in prelim test: 24567 Number of HSP's gapped (non-prelim): 54145 length of query: 816 length of database: 18,247,518 effective HSP length: 111 effective length of query: 705 effective length of database: 14,044,392 effective search space: 9901296360 effective search space used: 9901296360 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (22.0 bits) S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.