Guide to the Human Genome
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Search of human proteins with 239745855

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
sapiens]
         (870 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...  1772   0.0  
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]       1747   0.0  
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]        1743   0.0  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...  1737   0.0  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...  1737   0.0  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...  1735   0.0  
gi|53829385 leucine rich repeat containing 37B [Homo sapiens]         481   e-135
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   99   2e-20
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    99   2e-20
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   97   8e-20
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   97   8e-20
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    93   9e-19
gi|224458301 family with sequence similarity 186, member A [Homo...    91   5e-18
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    88   4e-17
gi|91982772 mucin 17 [Homo sapiens]                                    87   5e-17
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             84   4e-16
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              83   1e-15
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       83   1e-15
gi|151301154 mucin 6, gastric [Homo sapiens]                           80   1e-14
gi|116284392 mucin 2 precursor [Homo sapiens]                          79   2e-14
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        76   1e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        75   2e-13
gi|27881494 zonadhesin isoform 6 [Homo sapiens]                        75   2e-13
gi|163965366 nascent polypeptide-associated complex alpha subuni...    74   6e-13
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    74   8e-13
gi|58530876 melanoma antigen family C, 1 [Homo sapiens]                73   1e-12
gi|110349719 titin isoform N2-A [Homo sapiens]                         71   5e-12
gi|226437579 NAC alpha domain containing [Homo sapiens]                70   1e-11
gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]     70   1e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             69   2e-11

>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 1772 bits (4589), Expect = 0.0
 Identities = 870/870 (100%), Positives = 870/870 (100%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM
Sbjct: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 1747 bits (4525), Expect = 0.0
 Identities = 858/870 (98%), Positives = 859/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 1743 bits (4514), Expect = 0.0
 Identities = 856/870 (98%), Positives = 858/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+SW
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 1 [Homo sapiens]
          Length = 1635

 Score = 1737 bits (4498), Expect = 0.0
 Identities = 853/870 (98%), Positives = 855/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1   MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular
           protein isoform 2 [Homo sapiens]
          Length = 1700

 Score = 1737 bits (4498), Expect = 0.0
 Identities = 853/870 (98%), Positives = 855/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1   MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
           sapiens]
          Length = 1634

 Score = 1735 bits (4494), Expect = 0.0
 Identities = 853/870 (98%), Positives = 855/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60
           M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1   MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI  QLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
           QQPVQPSESSREVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQ PDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
          Length = 947

 Score =  481 bits (1237), Expect = e-135
 Identities = 280/534 (52%), Positives = 322/534 (60%), Gaps = 71/534 (13%)

Query: 13  MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESWSSHSSHFPRESP 72
           MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPE WSS SSH P ESP
Sbjct: 1   MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60

Query: 73  HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
           HAP  PA P DFD+LGPSASS+M A PQE TENL PFL   DSAGE PL PE FLA+ QD
Sbjct: 61  HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120

Query: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
           L DK +P+ERLP     L +D        P  +W                          
Sbjct: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180

Query: 159 --------------------SLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPE 198
                               SL EI+GI  QLS PQ QKQTL ++Y S DT YP SLPPE
Sbjct: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240

Query: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
           LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E   S Q
Sbjct: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300

Query: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
           QEAPALPPESSMESL  T  NHEV+VQPPGEDQA+Y+LP  TVKPADVEVT+TSEP NET
Sbjct: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360

Query: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESS 376
           ES+QAQQE PIQ PEE EPS+T       PP  P          +  + PS+  +   S 
Sbjct: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHP----------EVTLPPSDKGQAQHSH 410

Query: 377 LTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQ 436
           LT  E   QP +      + P         +   S +PPD  L I  EP+ E+G S   +
Sbjct: 411 LT--EATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALE 468

Query: 437 EATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
           +  A        +     +  GPP   ESS+++    VQ ET+ +  +   + N
Sbjct: 469 KTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDS---LVQSETAPEEQKASTSTN 519



 Score =  341 bits (874), Expect = 2e-93
 Identities = 195/344 (56%), Positives = 231/344 (67%), Gaps = 40/344 (11%)

Query: 533 PPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQP---PKKVVPQLRVYQGVT 589
           PPE   L+Q  ++P        PE++ +++ S   +E P Q    P++V P  +      
Sbjct: 251 PPEQVGLSQFHLEPKSQN----PETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQQEAPAL 306

Query: 590 NPTPGQDQ-AQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHP 648
            P    +  AQ P++  VTVQ           P  +  H   PK T V P   EVT+   
Sbjct: 307 PPESSMESLAQTPLNHEVTVQ----------PPGEDQAHYNLPKFT-VKPADVEVTMTSE 355

Query: 649 DQVQTQHSHLTR-ATVQPLDLGFTITPKSMTEVEPS-TALMTTAPPPGHPEVTLPPSDKG 706
            + +T+ +   + A +QP +           E EPS TAL TT PPP HPEVTLPPSDKG
Sbjct: 356 PKNETESTQAQQEAPIQPPE-----------EAEPSSTALRTTDPPPEHPEVTLPPSDKG 404

Query: 707 QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHS 766
           QAQHSHLT+ATVQPLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHS
Sbjct: 405 QAQHSHLTEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHS 464

Query: 767 TALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKAST 826
           TALEKT APHPD+VQ+LHRSLTEVTGPPT+LE +QDSLVQSE        TAPEEQKAST
Sbjct: 465 TALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKAST 516

Query: 827 STNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           STNICELCTCGDE LSC+ L+P+QRLRQVPVPEP+T+NG FT L
Sbjct: 517 STNICELCTCGDETLSCVGLSPKQRLRQVPVPEPDTYNGIFTTL 560


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 179/762 (23%), Positives = 266/762 (34%), Gaps = 109/762 (14%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIAR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 148 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 202

Query: 183 EYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST     ++ P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 203 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 258

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 318

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP---------- 346
                     TI S PT   E +    ++    P+E  P+ T++ AP  P          
Sbjct: 319 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378

Query: 347 ---------PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP 397
                    P +P E   +  ++  P  P E +     +  ++ TP  P E    T  P 
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA----PTTPKEPTPTTPKEPAPTTKEPA 434

Query: 398 GHHQTHHLDSPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATARLSG 444
               T    +P+   K             P +   T   EPS    T+      T   S 
Sbjct: 435 --PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSA 489

Query: 445 SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEH 502
                EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  
Sbjct: 490 PTTTKEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-- 544

Query: 503 PQTAEEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESMT 559
           P T +E   + T + AP  TP+ P     +   P     LT  T + L       P   T
Sbjct: 545 PTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 560 EVELSPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGL 615
             EL+PT  E PT    + P    P+         P P   +   P +P           
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------- 653

Query: 616 TITPEPTT-EVGHSTAPKRTI-VSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTI 672
              P PTT +    T PK T   + K P  T P  P   +   +     T    D     
Sbjct: 654 --EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711

Query: 673 TPKSMTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK 730
           TPK      P     TT   P P  P+ T P + K  A     T     P +L  T T  
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 768

Query: 731 P--TTEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPHPDRVQSL 783
           P  TT  KP+PTT +    T+ + P       P PTT ET   T  E +T        ++
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828

Query: 784 HRSLTEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
           H+S  E T P    EP   +L  S        T+  A T PE
Sbjct: 829 HKSPDEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 164/729 (22%), Positives = 249/729 (34%), Gaps = 125/729 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 311

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVSPMEHELSISEQQQPVQPSESSREVESSL 377
            +E     P+E  P+A ++ AP  P    P +P E   + +++  P  P E +     S 
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489

Query: 378 ----------TQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
                     T +  P  P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 545

Query: 428 EVGTSLVHQEATARLSGSGNDVEPPAIQHGGPP------------LLPESSEEAGPLAVQ 475
                            +  +  P   +   P             L P + E+  P   +
Sbjct: 546 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 476 Q--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
           +   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P      P
Sbjct: 606 ELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APTTP 660

Query: 534 PEHSHLTQATVQPLDLG--FTITPESMTEVELSPTMKETPTQP----PKKVVPQLRVYQG 587
            E +  T     P  L      TP+     EL+PT  + PT      P    P+     G
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK-----G 715

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTIT-PEPTTEVGHSTAPKRTIVSPKHPEVTLP 646
               TP +     P  P+ T        T+  P PTT       PK+       P  T  
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKPAPKELAPTTTKG 768

Query: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSD 704
                  + +  T     P       TPK      P     TT   PPP   EV+ P   
Sbjct: 769 PTSTTSDKPAPTTPKETAPT------TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP--- 819

Query: 705 KGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE----P 759
                                T T +PTT  K P  +T E S +P    L   P+    P
Sbjct: 820 ---------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 858

Query: 760 TTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
           TT+T  +T  E TT       +   R+  E T    ++   +++   +E  T++K +TA 
Sbjct: 859 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITAT 915

Query: 820 EEQKASTST 828
             Q  ST+T
Sbjct: 916 TTQVTSTTT 924



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 178/818 (21%), Positives = 275/818 (33%), Gaps = 145/818 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 327  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 375

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGIARQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 376  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 421

Query: 180  LQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 422  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 479

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 480  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 540  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 595

Query: 338  TQQEAPIEP----PVSPMEHELSISEQQQPVQPSESS----REVESSLTQQETPGQPPEH 389
             ++ AP  P    P +P E   +  E+  P  P  ++    +E   +  ++  P  P E 
Sbjct: 596  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655

Query: 390  HEVT------VSPPGHHQTHHLD-SPSVSVKPPDVQL--TIAAEPSAEVGTSLVHQEATA 440
               T       +P G   T   + +P+   KP   +L  T   EP++             
Sbjct: 656  APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715

Query: 441  RLSGSGNDVEPPAIQHGGPPL----LPESSEEAGPLAVQQE-------TSFQSPEPINNE 489
                +  +  P   +   P       P + +E  P   ++        T+ + P    ++
Sbjct: 716  TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 775

Query: 490  NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDL 549
             P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T      
Sbjct: 776  KPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEPT 826

Query: 550  GFTITP-ESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV 608
                +P ES  E+   PT K     P +  VP        T  TP   +      P +T 
Sbjct: 827  TIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT- 871

Query: 609  QLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
                   T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q    
Sbjct: 872  -------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTST 922

Query: 669  G------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
                   F IT    T + P        +TT      PE T  P D+  A +S  T    
Sbjct: 923  TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPKP 980

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPD 778
            Q          KPT   K   +T++  T P        P P   T     L  T+     
Sbjct: 981  Q----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1030

Query: 779  RVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             +Q+  R          E+ P  +    +E  T +  L
Sbjct: 1031 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 95/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329

Query: 539 LTQATVQPLDLGFTITPES-MTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  +  T  E +PT  KE     PK+  P          PT  + 
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 386

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +T  + T  +PK P  T   P     +
Sbjct: 387 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 439

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 440 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 488

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 489 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 542

Query: 773 TAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICE 832
            AP   +  +   + T+   P T  EPA  +  ++   T  K LT    +K + +T    
Sbjct: 543 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 599

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 600 APTTPEELAPTTPEEPTPTTPEEPAP 625



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/257 (22%), Positives = 96/257 (37%), Gaps = 15/257 (5%)

Query: 576 KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---STAPK 632
           +++  +L+V     N T  +   + PV       L +    +T   T+   H   ST+PK
Sbjct: 151 RELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK 210

Query: 633 RTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTITPKSMTEVEPSTALMTT 689
            T   P +P  +LP P+   ++ + LT     TV+  +   T    S    E +T+   T
Sbjct: 211 ITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 269

Query: 690 APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPP 749
                     L P+ K  A+ +   + T +   L       PTT  +P+ TT +  T   
Sbjct: 270 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 329

Query: 750 DLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSES 809
                  P+    T   +A      P P        + T+   P T  EPA  +  +   
Sbjct: 330 IKSAPTTPKEPAPTTTKSAPTTPKEPAP--------TTTKEPAPTTPKEPAPTTTKEPAP 381

Query: 810 YTQNKALTAPEEQKAST 826
            T   A T P+E   +T
Sbjct: 382 TTTKSAPTTPKEPAPTT 398


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 98.6 bits (244), Expect = 2e-20
 Identities = 179/762 (23%), Positives = 266/762 (34%), Gaps = 109/762 (14%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIAR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 189 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 243

Query: 183 EYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST     ++ P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 244 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 299

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 359

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP---------- 346
                     TI S PT   E +    ++    P+E  P+ T++ AP  P          
Sbjct: 360 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419

Query: 347 ---------PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP 397
                    P +P E   +  ++  P  P E +     +  ++ TP  P E    T  P 
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA----PTTPKEPTPTTPKEPAPTTKEPA 475

Query: 398 GHHQTHHLDSPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATARLSG 444
               T    +P+   K             P +   T   EPS    T+      T   S 
Sbjct: 476 --PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSA 530

Query: 445 SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEH 502
                EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  
Sbjct: 531 PTTTKEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA-- 585

Query: 503 PQTAEEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESMT 559
           P T +E   + T + AP  TP+ P     +   P     LT  T + L       P   T
Sbjct: 586 PTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 560 EVELSPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGL 615
             EL+PT  E PT    + P    P+         P P   +   P +P           
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK---------- 694

Query: 616 TITPEPTT-EVGHSTAPKRTI-VSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTI 672
              P PTT +    T PK T   + K P  T P  P   +   +     T    D     
Sbjct: 695 --EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752

Query: 673 TPKSMTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK 730
           TPK      P     TT   P P  P+ T P + K  A     T     P +L  T T  
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 809

Query: 731 P--TTEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPHPDRVQSL 783
           P  TT  KP+PTT +    T+ + P       P PTT ET   T  E +T        ++
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869

Query: 784 HRSLTEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
           H+S  E T P    EP   +L  S        T+  A T PE
Sbjct: 870 HKSPDEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 164/729 (22%), Positives = 249/729 (34%), Gaps = 125/729 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 294 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 352

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 353 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 413 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVSPMEHELSISEQQQPVQPSESSREVESSL 377
            +E     P+E  P+A ++ AP  P    P +P E   + +++  P  P E +     S 
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530

Query: 378 ----------TQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
                     T +  P  P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 586

Query: 428 EVGTSLVHQEATARLSGSGNDVEPPAIQHGGPP------------LLPESSEEAGPLAVQ 475
                            +  +  P   +   P             L P + E+  P   +
Sbjct: 587 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 476 Q--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
           +   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P      P
Sbjct: 647 ELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APTTP 701

Query: 534 PEHSHLTQATVQPLDLG--FTITPESMTEVELSPTMKETPTQP----PKKVVPQLRVYQG 587
            E +  T     P  L      TP+     EL+PT  + PT      P    P+     G
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK-----G 756

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTIT-PEPTTEVGHSTAPKRTIVSPKHPEVTLP 646
               TP +     P  P+ T        T+  P PTT       PK+       P  T  
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKPAPKELAPTTTKG 809

Query: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSD 704
                  + +  T     P       TPK      P     TT   PPP   EV+ P   
Sbjct: 810 PTSTTSDKPAPTTPKETAPT------TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP--- 860

Query: 705 KGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE----P 759
                                T T +PTT  K P  +T E S +P    L   P+    P
Sbjct: 861 ---------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 899

Query: 760 TTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
           TT+T  +T  E TT       +   R+  E T    ++   +++   +E  T++K +TA 
Sbjct: 900 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITAT 956

Query: 820 EEQKASTST 828
             Q  ST+T
Sbjct: 957 TTQVTSTTT 965



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 178/818 (21%), Positives = 275/818 (33%), Gaps = 145/818 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 368  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 416

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGIARQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 417  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 462

Query: 180  LQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 463  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 520

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 521  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 581  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 636

Query: 338  TQQEAPIEP----PVSPMEHELSISEQQQPVQPSESS----REVESSLTQQETPGQPPEH 389
             ++ AP  P    P +P E   +  E+  P  P  ++    +E   +  ++  P  P E 
Sbjct: 637  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696

Query: 390  HEVT------VSPPGHHQTHHLD-SPSVSVKPPDVQL--TIAAEPSAEVGTSLVHQEATA 440
               T       +P G   T   + +P+   KP   +L  T   EP++             
Sbjct: 697  APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756

Query: 441  RLSGSGNDVEPPAIQHGGPPL----LPESSEEAGPLAVQQE-------TSFQSPEPINNE 489
                +  +  P   +   P       P + +E  P   ++        T+ + P    ++
Sbjct: 757  TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 816

Query: 490  NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDL 549
             P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T      
Sbjct: 817  KPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEPT 867

Query: 550  GFTITP-ESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV 608
                +P ES  E+   PT K     P +  VP        T  TP   +      P +T 
Sbjct: 868  TIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT- 912

Query: 609  QLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
                   T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q    
Sbjct: 913  -------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTST 963

Query: 669  G------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
                   F IT    T + P        +TT      PE T  P D+  A +S  T    
Sbjct: 964  TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPKP 1021

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPD 778
            Q          KPT   K   +T++  T P        P P   T     L  T+     
Sbjct: 1022 Q----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 1071

Query: 779  RVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             +Q+  R          E+ P  +    +E  T +  L
Sbjct: 1072 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 95/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 311 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370

Query: 539 LTQATVQPLDLGFTITPES-MTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  +  T  E +PT  KE     PK+  P          PT  + 
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 427

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +T  + T  +PK P  T   P     +
Sbjct: 428 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 480

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 481 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 529

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 530 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 583

Query: 773 TAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICE 832
            AP   +  +   + T+   P T  EPA  +  ++   T  K LT    +K + +T    
Sbjct: 584 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 640

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 641 APTTPEELAPTTPEEPTPTTPEEPAP 666



 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 59/257 (22%), Positives = 96/257 (37%), Gaps = 15/257 (5%)

Query: 576 KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---STAPK 632
           +++  +L+V     N T  +   + PV       L +    +T   T+   H   ST+PK
Sbjct: 192 RELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPK 251

Query: 633 RTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTITPKSMTEVEPSTALMTT 689
            T   P +P  +LP P+   ++ + LT     TV+  +   T    S    E +T+   T
Sbjct: 252 ITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKET 310

Query: 690 APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPP 749
                     L P+ K  A+ +   + T +   L       PTT  +P+ TT +  T   
Sbjct: 311 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 370

Query: 750 DLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSES 809
                  P+    T   +A      P P        + T+   P T  EPA  +  +   
Sbjct: 371 IKSAPTTPKEPAPTTTKSAPTTPKEPAP--------TTTKEPAPTTPKEPAPTTTKEPAP 422

Query: 810 YTQNKALTAPEEQKAST 826
            T   A T P+E   +T
Sbjct: 423 TTTKSAPTTPKEPAPTT 439


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 96.7 bits (239), Expect = 8e-20
 Identities = 171/716 (23%), Positives = 248/716 (34%), Gaps = 101/716 (14%)

Query: 169 QLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
           +++TP +   T Q+   ST     ++ P  +  +   PP  S+    +   +  ET   E
Sbjct: 98  KVTTPDTS--TTQHNKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVE 151

Query: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
           T E   ++        +     +E  S  +  A  L P S + +   P  E + + P   
Sbjct: 152 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 211

Query: 289 QAYYHLPNITVKPADVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
                 P    +PA          TI S PT   E +    ++    P+E  P+ T++ A
Sbjct: 212 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 271

Query: 343 PIEP-------------------PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETP 383
           P  P                   P +P E   +  ++  P  P E +     +  ++ TP
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA----PTTPKEPTP 327

Query: 384 GQPPEHHEVTVSPPGHHQTHHLDSPSVSVK-------------PPDVQLTIAAEPSAEVG 430
             P E    T  P     T    +P+   K             P +   T   EPS    
Sbjct: 328 TTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP--- 382

Query: 431 TSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINN 488
           T+      T   S      EP        P  P   +E  P   ++   T+ + P P   
Sbjct: 383 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTP 439

Query: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQ 545
           + P+PT  +  A  P T +E   + T + AP  TP+ P     +   P     LT  T +
Sbjct: 440 KKPAPTTPKEPA--PTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPE 496

Query: 546 PLDLGFTITPESMTEVELSPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
            L       P   T  EL+PT  E PT    + P    P+         P P   +   P
Sbjct: 497 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 556

Query: 602 VSPSVTVQLLDLGLTITPEPTT-EVGHSTAPKRTI-VSPKHPEVTLP-HPDQVQTQHSHL 658
            +P              P PTT +    T PK T   + K P  T P  P   +   +  
Sbjct: 557 TTPK------------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 604

Query: 659 TRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQA 716
              T    D     TPK      P     TT   P P  P+ T P + K  A     T  
Sbjct: 605 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPK 661

Query: 717 TVQPLDLELTITTKP--TTEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTAL 769
              P +L  T T  P  TT  KP+PTT +    T+ + P       P PTT ET   T  
Sbjct: 662 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 721

Query: 770 EKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
           E +T        ++H+S  E T P    EP   +L  S        T+  A T PE
Sbjct: 722 EVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 776



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 164/729 (22%), Positives = 249/729 (34%), Gaps = 125/729 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 218

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVSPMEHELSISEQQQPVQPSESSREVESSL 377
            +E     P+E  P+A ++ AP  P    P +P E   + +++  P  P E +     S 
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396

Query: 378 ----------TQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
                     T +  P  P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 452

Query: 428 EVGTSLVHQEATARLSGSGNDVEPPAIQHGGPP------------LLPESSEEAGPLAVQ 475
                            +  +  P   +   P             L P + E+  P   +
Sbjct: 453 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512

Query: 476 Q--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
           +   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P      P
Sbjct: 513 ELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APTTP 567

Query: 534 PEHSHLTQATVQPLDLG--FTITPESMTEVELSPTMKETPTQP----PKKVVPQLRVYQG 587
            E +  T     P  L      TP+     EL+PT  + PT      P    P+     G
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK-----G 622

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTIT-PEPTTEVGHSTAPKRTIVSPKHPEVTLP 646
               TP +     P  P+ T        T+  P PTT       PK+       P  T  
Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKPAPKELAPTTTKG 675

Query: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSD 704
                  + +  T     P       TPK      P     TT   PPP   EV+ P   
Sbjct: 676 PTSTTSDKPAPTTPKETAPT------TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP--- 726

Query: 705 KGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE----P 759
                                T T +PTT  K P  +T E S +P    L   P+    P
Sbjct: 727 ---------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 765

Query: 760 TTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
           TT+T  +T  E TT       +   R+  E T    ++   +++   +E  T++K +TA 
Sbjct: 766 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITAT 822

Query: 820 EEQKASTST 828
             Q  ST+T
Sbjct: 823 TTQVTSTTT 831



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 178/818 (21%), Positives = 275/818 (33%), Gaps = 145/818 (17%)

Query: 68  PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
           P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 234 PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 282

Query: 128 ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGIARQLSTPQSQKQT 179
             +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 328

Query: 180 LQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
              E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 386

Query: 240 QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
           + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 285 ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
              P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 502

Query: 338 TQQEAPIEP----PVSPMEHELSISEQQQPVQPSESS----REVESSLTQQETPGQPPEH 389
            ++ AP  P    P +P E   +  E+  P  P  ++    +E   +  ++  P  P E 
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562

Query: 390 HEVT------VSPPGHHQTHHLD-SPSVSVKPPDVQL--TIAAEPSAEVGTSLVHQEATA 440
              T       +P G   T   + +P+   KP   +L  T   EP++             
Sbjct: 563 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 622

Query: 441 RLSGSGNDVEPPAIQHGGPPL----LPESSEEAGPLAVQQE-------TSFQSPEPINNE 489
               +  +  P   +   P       P + +E  P   ++        T+ + P    ++
Sbjct: 623 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 682

Query: 490 NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDL 549
            P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T      
Sbjct: 683 KPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEPT 733

Query: 550 GFTITP-ESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV 608
               +P ES  E+   PT K     P +  VP        T  TP   +      P +T 
Sbjct: 734 TIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT- 778

Query: 609 QLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
                  T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q    
Sbjct: 779 -------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTST 829

Query: 669 G------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
                  F IT    T + P        +TT      PE T  P D+  A +S  T    
Sbjct: 830 TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPKP 887

Query: 719 QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPD 778
           Q          KPT   K   +T++  T P        P P   T     L  T+     
Sbjct: 888 Q----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 937

Query: 779 RVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
            +Q+  R          E+ P  +    +E  T +  L
Sbjct: 938 MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 95/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 236

Query: 539 LTQATVQPLDLGFTITPES-MTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  +  T  E +PT  KE     PK+  P          PT  + 
Sbjct: 237 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 293

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +T  + T  +PK P  T   P     +
Sbjct: 294 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 347 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 395

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 449

Query: 773 TAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICE 832
            AP   +  +   + T+   P T  EPA  +  ++   T  K LT    +K + +T    
Sbjct: 450 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 506

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAP 532



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 52/214 (24%), Positives = 82/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STAPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST+PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 159

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTG 792
           T  +P+ TT +  T          P+    T   +A      P P        + T+   
Sbjct: 220 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--------TTTKEPA 271

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEQKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 96.7 bits (239), Expect = 8e-20
 Identities = 171/716 (23%), Positives = 248/716 (34%), Gaps = 101/716 (14%)

Query: 169 QLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
           +++TP +   T Q+   ST     ++ P  +  +   PP  S+    +   +  ET   E
Sbjct: 139 KVTTPDTS--TTQHNKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVE 192

Query: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
           T E   ++        +     +E  S  +  A  L P S + +   P  E + + P   
Sbjct: 193 TKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALT 252

Query: 289 QAYYHLPNITVKPADVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
                 P    +PA          TI S PT   E +    ++    P+E  P+ T++ A
Sbjct: 253 TPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPA 312

Query: 343 PIEP-------------------PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETP 383
           P  P                   P +P E   +  ++  P  P E +     +  ++ TP
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA----PTTPKEPTP 368

Query: 384 GQPPEHHEVTVSPPGHHQTHHLDSPSVSVK-------------PPDVQLTIAAEPSAEVG 430
             P E    T  P     T    +P+   K             P +   T   EPS    
Sbjct: 369 TTPKEPAPTTKEPA--PTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP--- 423

Query: 431 TSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINN 488
           T+      T   S      EP        P  P   +E  P   ++   T+ + P P   
Sbjct: 424 TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTP 480

Query: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQ 545
           + P+PT  +  A  P T +E   + T + AP  TP+ P     +   P     LT  T +
Sbjct: 481 KKPAPTTPKEPA--PTTPKEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPE 537

Query: 546 PLDLGFTITPESMTEVELSPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
            L       P   T  EL+PT  E PT    + P    P+         P P   +   P
Sbjct: 538 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 597

Query: 602 VSPSVTVQLLDLGLTITPEPTT-EVGHSTAPKRTI-VSPKHPEVTLP-HPDQVQTQHSHL 658
            +P              P PTT +    T PK T   + K P  T P  P   +   +  
Sbjct: 598 TTPK------------EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 645

Query: 659 TRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQA 716
              T    D     TPK      P     TT   P P  P+ T P + K  A     T  
Sbjct: 646 KEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPK 702

Query: 717 TVQPLDLELTITTKP--TTEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETGHSTAL 769
              P +L  T T  P  TT  KP+PTT +    T+ + P       P PTT ET   T  
Sbjct: 703 KPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS 762

Query: 770 EKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
           E +T        ++H+S  E T P    EP   +L  S        T+  A T PE
Sbjct: 763 EVSTPTTTKEPTTIHKSPDEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 817



 Score = 95.1 bits (235), Expect = 2e-19
 Identities = 164/729 (22%), Positives = 249/729 (34%), Gaps = 125/729 (17%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 259

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVSPMEHELSISEQQQPVQPSESSREVESSL 377
            +E     P+E  P+A ++ AP  P    P +P E   + +++  P  P E +     S 
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437

Query: 378 ----------TQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
                     T +  P  P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 493

Query: 428 EVGTSLVHQEATARLSGSGNDVEPPAIQHGGPP------------LLPESSEEAGPLAVQ 475
                            +  +  P   +   P             L P + E+  P   +
Sbjct: 494 TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553

Query: 476 Q--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
           +   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P      P
Sbjct: 554 ELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APTTP 608

Query: 534 PEHSHLTQATVQPLDLG--FTITPESMTEVELSPTMKETPTQP----PKKVVPQLRVYQG 587
            E +  T     P  L      TP+     EL+PT  + PT      P    P+     G
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK-----G 663

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTIT-PEPTTEVGHSTAPKRTIVSPKHPEVTLP 646
               TP +     P  P+ T        T+  P PTT       PK+       P  T  
Sbjct: 664 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKPAPKELAPTTTKG 716

Query: 647 HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLPPSD 704
                  + +  T     P       TPK      P     TT   PPP   EV+ P   
Sbjct: 717 PTSTTSDKPAPTTPKETAPT------TPKEPAPTTPKKPAPTTPETPPPTTSEVSTP--- 767

Query: 705 KGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PSPTTEETSTQPPDLGLAIIPE----P 759
                                T T +PTT  K P  +T E S +P    L   P+    P
Sbjct: 768 ---------------------TTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP 806

Query: 760 TTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
           TT+T  +T  E TT       +   R+  E T    ++   +++   +E  T++K +TA 
Sbjct: 807 TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM--TKETATTTEKTTESK-ITAT 863

Query: 820 EEQKASTST 828
             Q  ST+T
Sbjct: 864 TTQVTSTTT 872



 Score = 92.8 bits (229), Expect = 1e-18
 Identities = 178/818 (21%), Positives = 275/818 (33%), Gaps = 145/818 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 275  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 323

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGIARQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 324  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 369

Query: 180  LQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 370  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 427

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 428  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 543

Query: 338  TQQEAPIEP----PVSPMEHELSISEQQQPVQPSESS----REVESSLTQQETPGQPPEH 389
             ++ AP  P    P +P E   +  E+  P  P  ++    +E   +  ++  P  P E 
Sbjct: 544  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603

Query: 390  HEVT------VSPPGHHQTHHLD-SPSVSVKPPDVQL--TIAAEPSAEVGTSLVHQEATA 440
               T       +P G   T   + +P+   KP   +L  T   EP++             
Sbjct: 604  APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 663

Query: 441  RLSGSGNDVEPPAIQHGGPPL----LPESSEEAGPLAVQQE-------TSFQSPEPINNE 489
                +  +  P   +   P       P + +E  P   ++        T+ + P    ++
Sbjct: 664  TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD 723

Query: 490  NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDL 549
             P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T      
Sbjct: 724  KPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEPT 774

Query: 550  GFTITP-ESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV 608
                +P ES  E+   PT K     P +  VP        T  TP   +      P +T 
Sbjct: 775  TIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT- 819

Query: 609  QLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
                   T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q    
Sbjct: 820  -------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTST 870

Query: 669  G------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
                   F IT    T + P        +TT      PE T  P D+  A +S  T    
Sbjct: 871  TTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPKP 928

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPD 778
            Q          KPT   K   +T++  T P        P P   T     L  T+     
Sbjct: 929  Q----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEA 978

Query: 779  RVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             +Q+  R          E+ P  +    +E  T +  L
Sbjct: 979  MLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016



 Score = 64.7 bits (156), Expect = 4e-10
 Identities = 95/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 277

Query: 539 LTQATVQPLDLGFTITPES-MTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  +  T  E +PT  KE     PK+  P          PT  + 
Sbjct: 278 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 334

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +T  + T  +PK P  T   P     +
Sbjct: 335 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 388 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 436

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 490

Query: 773 TAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICE 832
            AP   +  +   + T+   P T  EPA  +  ++   T  K LT    +K + +T    
Sbjct: 491 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 547

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAP 573



 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 52/214 (24%), Positives = 82/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STAPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST+PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 200

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTG 792
           T  +P+ TT +  T          P+    T   +A      P P        + T+   
Sbjct: 261 TPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAP--------TTTKEPA 312

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEQKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 93.2 bits (230), Expect = 9e-19
 Identities = 163/655 (24%), Positives = 242/655 (36%), Gaps = 105/655 (16%)

Query: 52   NPLGPP--ESWSSHSSHFPRESPHAPTLPADPW-DFDHLG-PSASSEMPAPPQESTENLV 107
            +PL PP  ES +S      R SP    LPA P  +  HL  P   S +  PP+ES  +  
Sbjct: 447  SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 108  PFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQ-ERLPVSPKKLKKDPAQRWSLAEIIGI 166
            P    +    E PL P +       L+  LSP  E  P+SP   ++ P            
Sbjct: 507  PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESP------------ 553

Query: 167  ARQLSTPQSQKQTLQNEYSSTDTPYPSSLP--PELRVKSDEPPGPSEQVGPSQFHLEPET 224
               LS P  +  T     +S  +P P   P  P        PP  + ++ P  F   P +
Sbjct: 554  ---LSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRLFPP-FEESPLS 609

Query: 225  QNPETL------EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNH 278
              PE        E  + S   +++P   P   EE P S   E   L P   +  L+ P  
Sbjct: 610  PPPEESPLSPPPEASRLSPPPEDSPMSPPP--EESPMSPPPEVSRLSPLPVVSRLSPPPE 667

Query: 279  EVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSAT 338
            E  + PP E+      P  +      E + TS P  ++ +S   +++ +  P E  P   
Sbjct: 668  ESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLL- 726

Query: 339  QQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLT-QQETPGQPPEHHE--VTVS 395
                P EP + P      +S   +P +P  S R  E  L+ Q E P   P+  E  +   
Sbjct: 727  --PLPEEPQLCPRSEGPHLS--PRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAV 782

Query: 396  PPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEP---- 451
            P   H +   + P +S +P ++ L+   E   E   S V +E         + + P    
Sbjct: 783  PEEPHLSPQAEGPHLSPQPEELHLSPQTE---EPHLSPVPEEPCLSPQPEESHLSPQSEE 839

Query: 452  ------PAIQH-----GGPPLLP---ESSEEAGPLAVQQETSFQSP-----------EPI 486
                  P   H       PPL P   +  EE G     +E     P           EP 
Sbjct: 840  PCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPSLSPLLGEPA 899

Query: 487  NNENPSPTQQEAAAEHPQTAEEGESSLTHQ---EAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             +E   P       E P  +  GE SL+ Q     P   P  P +  A PP  S L +  
Sbjct: 900  LSEPGEPPLSPLPEELP-LSPSGEPSLSPQLMPPDPLPPPLSPIITAAAPPALSPLGE-- 956

Query: 544  VQPLDLGFTITPESMTEVELSPTMKETPTQPPKKV-------VPQLRVYQGVTNPTPGQD 596
               L+  F    +S  E  L+  + ETP  PP +        VP +     +  P+PG  
Sbjct: 957  ---LEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPM-----ILPPSPGS- 1007

Query: 597  QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKR---TIVSPKHPEVTLPHP 648
                PV P+  + +  L     P+ +  + HS  P+    +  SP    +++P P
Sbjct: 1008 ----PVGPASPILMEPL----PPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSP 1054



 Score = 81.6 bits (200), Expect = 3e-15
 Identities = 168/672 (25%), Positives = 242/672 (36%), Gaps = 153/672 (22%)

Query: 183 EYSSTDTPYPSSL-------PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
           E   T T  P +L       P    V S +P  P    GP Q   +P  +    LE    
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP----GPLQCEAKPLGKAGVQLEPQLE 431

Query: 236 SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS-VQPPGEDQAYYHL 294
           + L +E P   P           +E+P  PP    ES T P  E S + PP E+     L
Sbjct: 432 APLNEEMPLLPPP----------EESPLSPPPE--ESPTSPPPEASRLSPPPEELPASPL 479

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHE 354
           P         E    S P  E+  S   +E+P+  P E  P +  +E+P+ PP       
Sbjct: 480 P---------EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPP------- 523

Query: 355 LSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKP 414
                ++ P  P+             ETP  PP      +SPP        +SP   + P
Sbjct: 524 -----EESPPSPA------------LETPLSPPPEAS-PLSPPFE------ESP---LSP 556

Query: 415 PDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAV 474
           P  +L  +  P A            +RLS       PP      PP  PE S    P++ 
Sbjct: 557 PPEELPTSPPPEA------------SRLS------PPPEESPMSPP--PEES----PMSP 592

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP--EFPNVVVAQ 532
             E S   P P      SP  +E+    P   E    S   +++P   P  E P   ++ 
Sbjct: 593 PPEASRLFP-PFEESPLSPPPEESPLSPP--PEASRLSPPPEDSPMSPPPEESP---MSP 646

Query: 533 PPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP---KKVVPQLRVYQGVT 589
           PPE S L+     PL +   ++P    E  LSP  +E+PT PP    ++ P        T
Sbjct: 647 PPEVSRLS-----PLPVVSRLSPPP-EESPLSPPPEESPTSPPPEASRLSPPPE--DSPT 698

Query: 590 NPTPGQDQAQHPVSPS-VTVQLLDLGLTITPE-----PTTEVGH-STAPKRTIVSPKHPE 642
           +P P    A  P   S +++ L +  L   PE     P +E  H S  P+   +SP+  E
Sbjct: 699 SPPPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEE 758

Query: 643 VTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE-----PSTALMTTAPPPGHPE 697
              PH    Q +  HL+    +P        P    + E     P    +  +P    P 
Sbjct: 759 ---PHLSP-QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPH 814

Query: 698 VTLPPSD---KGQAQHSHLTQATVQP----------LDLELTITTKPTTEVKPSPTTEET 744
           ++  P +     Q + SHL+  + +P          L  EL    KP    +P    EE 
Sbjct: 815 LSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPEL---EKPPLSPRPEKPPEEP 871

Query: 745 STQPPDLGLAIIPEP--------TTETGHSTALEKTTAPHPDRV---QSLHRSLTEVTGP 793
              P    L + P P          E   S   E   +P P+ +    S   SL+    P
Sbjct: 872 GQCPAPEELPLFPPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMP 931

Query: 794 PTELEPAQDSLV 805
           P  L P    ++
Sbjct: 932 PDPLPPPLSPII 943



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 144/685 (21%), Positives = 224/685 (32%), Gaps = 131/685 (19%)

Query: 87   LGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LEPEQFLASQQDLKDKLSPQ---ER 142
            LGP     MP  P      LV  L      G Q  L P Q    QQ     L PQ    +
Sbjct: 3769 LGPKPQGLMP--PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQ 3826

Query: 143  LPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVK 202
            + ++  ++   P        ++G   +L T Q Q+Q  Q++   +     S L   L   
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMG--HRLVTAQQQQQQQQHQQQGSMAGL-SHLQQSLMSH 3883

Query: 203  SDEPPGPSEQVGP---------------------SQFHLEPETQNPETLEDIQSSSLQQE 241
            S +P   ++ +G                       Q   + + Q  +  +  Q   LQQ+
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 242  APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHL--PNITV 299
               QL Q  ++     QQ+      +   + + L N   ++  P + Q       P +  
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003

Query: 300  KPAD---------------------VEVTITSEPTNETESSQAQQETPIQFPEEVEPSAT 338
            KP                       V+  ++SE    TE     Q  P+      E  AT
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSE---ATEGPSTHQGGPLAIGTTPESMAT 4060

Query: 339  QQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEV--TVSP 396
             +   ++P +S     L +  Q QP QP  SS +++  L     PGQ  +   +  T   
Sbjct: 4061 -EPGEVKPSLSGDSQLLLV--QPQP-QPQPSSLQLQPPL---RLPGQQQQQVSLLHTAGG 4113

Query: 397  PGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGND-VEPPAIQ 455
              H Q     S   S  P      + A+PS  +G        T  L G     +E P   
Sbjct: 4114 GSHGQLGSGSSSEASSVP-----HLLAQPSVSLGDQ--PGSMTQNLLGPQQPMLERPMQN 4166

Query: 456  HGGP------PLLPESS--------EEAGPLAVQQETSFQSPEPINNENPSPTQQEAA-- 499
            + GP      P+L               G L  Q +        + + +P   QQ  A  
Sbjct: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226

Query: 500  -AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPES- 557
                 Q ++    +  +QE   QT     ++  QP               LG    P++ 
Sbjct: 4227 MQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQP--------------QLGGFPGPQTG 4272

Query: 558  -MTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
             + E+   P  +  P  P            G  +PTP     Q P  PS   QL      
Sbjct: 4273 PLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPS---QL------ 4323

Query: 617  ITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
              P P++++     P    + P HP    P    ++     ++ A  Q  D   T+  K 
Sbjct: 4324 --PSPSSQL-----PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD---TLFSKG 4373

Query: 677  MTEVEPSTALMTTAPP------PGH 695
            +   +P   L  T  P      PGH
Sbjct: 4374 LGPWDPPDNLAETQKPEQSSLVPGH 4398



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 70/286 (24%), Positives = 100/286 (34%), Gaps = 36/286 (12%)

Query: 503  PQTAEEGESSLTHQEAPAQT--PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTE 560
            PQ   +  S      APA    P FP      PP  S  T A  QP  LG +  P +   
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-TGAPAQPPMLGASSRPGAGQP 2223

Query: 561  VELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             E   T   TP   P    P L+         P  D    P SP V        L ++P 
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNLAVPESPGVGGGKASEPL-LSPP 2276

Query: 621  PTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHS--HLTRATVQPLDL-GFTITPKSM 677
            P  E   +   K+  +    P    P+   V +  S  HL    ++  D+    +TP++ 
Sbjct: 2277 PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA- 2335

Query: 678  TEVEPSTALMTTAP------------PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL 725
            ++VEP +  +   P            PP HP++  P S         LT     P     
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 726  ------TITTKPTTEVKPSPTTEETSTQP----PDLGLAIIPEPTT 761
                  ++ + P + V  SP ++ +S  P    P    A  P P T
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 65/276 (23%), Positives = 98/276 (35%), Gaps = 33/276 (11%)

Query: 215  PSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEE--EPSSMQQEAPALPPESSMES 272
            P   HL P+ Q       +Q    Q +A  Q P   E   + S +Q      P       
Sbjct: 4209 PQLRHLSPQQQQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPG 4268

Query: 273  -LTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET--PIQF 329
              T P  E+   P  +       P +   P  +       P + T    + QE   P Q 
Sbjct: 4269 PQTGPLQELGAGPRPQGP-----PRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQL 4323

Query: 330  PEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEH 389
            P       T+ + P   P +P     ++      V P+ +++  ++  ++   P  PP++
Sbjct: 4324 PSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPA-AAQLADTLFSKGLGPWDPPDN 4382

Query: 390  HEVTVSP------PGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAE---VGTSLVHQEATA 440
               T  P      PGH     LD  +  V P   QL+I  EP  E   +G   V +EA  
Sbjct: 4383 LAETQKPEQSSLVPGH-----LDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANG 4437

Query: 441  RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
               G+     P    H    LL     EAG L +Q+
Sbjct: 4438 EPIGA-----PGTSNH---LLLAGPRSEAGHLLLQK 4465



 Score = 37.7 bits (86), Expect = 0.047
 Identities = 86/397 (21%), Positives = 129/397 (32%), Gaps = 26/397 (6%)

Query: 53   PLGP-PESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLD 111
            PL P PE      S  P  SP    +P DP     L P  ++  P       E   PF  
Sbjct: 907  PLSPLPEELPLSPSGEPSLSPQL--MPPDPLP-PPLSPIITAAAPPALSPLGELEYPFGA 963

Query: 112  TWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLS 171
              DS  E PL     L +      + +  +  PV P  L   P      A  I +     
Sbjct: 964  KGDSDPESPLAAP-ILETPISPPPEANCTDPEPVPPMILPPSPGSPVGPASPILME---P 1019

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
             P      LQ+     ++P     PP L +    P  P  +V       E      E + 
Sbjct: 1020 LPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVS 1079

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
            + +  +L+  A + LP  + +        APAL   S +   T P   +           
Sbjct: 1080 EPECPALEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDA--------- 1130

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
               P    +P     ++ SE          ++  P+  P EV P   Q      P     
Sbjct: 1131 ---PGSQPEPGQTPGSLASELKGSPVLLDPEELAPVT-PMEVYPECKQTAGQGSPCEEQE 1186

Query: 352  EHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP---GHHQTHHLD-S 407
            E    ++     +  S+   E+ S+L+Q +     P    +  SP    G   +  L  S
Sbjct: 1187 EPRAPVAPTPPTLIKSDIVNEI-SNLSQGDASASFPGSEPLLGSPDPEGGGSLSMELGVS 1245

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSG 444
              VS    +  L +  +   E   SL+    TA   G
Sbjct: 1246 TDVSPARDEGSLRLCTDSLPETDDSLLCDAGTAISGG 1282



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 112/608 (18%), Positives = 211/608 (34%), Gaps = 106/608 (17%)

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ----EAPALPPESSMESLTLP 276
            + + Q  +  +  Q S++   +P+Q P+LL + P  +      + P  PP      L L 
Sbjct: 3599 QQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658

Query: 277  NHEVSV--QPPG--------EDQAYYHL--------PNITVKPADVEVTITSEPTNETES 318
               +++  QP G        + Q   H         P+    P ++ +      +   + 
Sbjct: 3659 PGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718

Query: 319  SQAQ-QETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREV---- 373
             Q Q Q+  +Q  ++++    QQ+         +  +++I +QQQ     ++++ +    
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQ-----QHLLGQVAIQQQQQQGPGVQTNQALGPKP 3773

Query: 374  ---------ESSLTQQETPGQPP----------------EHHEVTVSPPGHHQTHHLDSP 408
                     +  L QQ +P QPP                + H   + P G H+   +   
Sbjct: 3774 QGLMPPSSHQGLLVQQLSP-QPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQVLMTQS 3832

Query: 409  SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSG---NDVEPPAIQHGGPPLLPES 465
             V   P   Q          V      Q+   +  GS    + ++   + H G P L  S
Sbjct: 3833 RVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL--S 3890

Query: 466  SEEAGPL-AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPE 524
            ++  G L  +QQ+   Q  + +  +     QQ+   +  Q  ++ +     Q+   Q  +
Sbjct: 3891 AQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQLQQ 3950

Query: 525  FPNVVVAQPPEHSHLTQATVQPLDLGF------TITP--ESMTEVELSPTMKETPTQ--- 573
                +  Q  +     Q   Q   +G        ++P  +   +V L P M   P Q   
Sbjct: 3951 QQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQHFS 4010

Query: 574  PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH----ST 629
             P  + P L +            + Q+ V P+V+ +        T  P+T  G      T
Sbjct: 4011 SPGALGPTLLL----------TGKEQNTVDPAVSSE-------ATEGPSTHQGGPLAIGT 4053

Query: 630  APKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP--KSMTEVEPSTALM 687
             P+     P   + +L    Q+      L +   QP      + P  +   + +   +L+
Sbjct: 4054 TPESMATEPGEVKPSLSGDSQLL-----LVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLL 4108

Query: 688  TTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK---PTTEVKPSPTTEET 744
             TA    H ++    S +  +    L Q +V   D   ++T     P   +   P    T
Sbjct: 4109 HTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNT 4168

Query: 745  STQPPDLG 752
              QPP  G
Sbjct: 4169 GPQPPKPG 4176



 Score = 34.3 bits (77), Expect = 0.52
 Identities = 108/499 (21%), Positives = 172/499 (34%), Gaps = 118/499 (23%)

Query: 114  DSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTP 173
            D+A  +PL P+         K      +RL  S KKL+K+   R S A +  + ++LS  
Sbjct: 4511 DAAARKPLTPKP--------KRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL 4562

Query: 174  QSQKQTLQNEYSSTDTPYPSSLP----PELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
               +  +   +S    P+ S  P     +LR        P+     SQ   +    NP T
Sbjct: 4563 PLTEPAITANFSLF-APFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPP---- 285
                         P+ LP      P S+QQ+         M +   P+ E+   P     
Sbjct: 4622 ------------PPSSLPPT---PPPSVQQK---------MVNGVTPSEELGEHPKDAAS 4657

Query: 286  GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQ-----Q 340
              D          VK  D+   + + P N+TE  + + +     P+ + P+++      +
Sbjct: 4658 ARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717

Query: 341  EAPIEP---------------PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQ 385
            EAP  P               PV P+    SI     PV P              E PG+
Sbjct: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASI-----PVFPDTK----PYGALGLEVPGK 4768

Query: 386  PPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSL--VHQEATARLS 443
             P    VT    G           VS     V LT++A  +  +   +  V +  + ++ 
Sbjct: 4769 LP----VTTWEKG-------KGSEVS-----VMLTVSAAAAKNLNGVMVAVAELLSMKIP 4812

Query: 444  GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHP 503
             S   + P +    G    P+  E  GP   ++    +SP+      P   +Q  A    
Sbjct: 4813 NSYEVLFPESPARAGTE--PKKGEAEGPGGKEKGLEGKSPD----TGPDWLKQFDAVLPG 4866

Query: 504  QTAEEGES--SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEV 561
             T +      SL  QE+PA  P         P +HS             +T    ++   
Sbjct: 4867 YTLKSQLDILSLLKQESPAPEP---------PTQHS-------------YTYNVSNLDVR 4904

Query: 562  ELSPTMKETPTQPPKKVVP 580
            +LS    E P+ PP  + P
Sbjct: 4905 QLSAPPPEEPSPPPSPLAP 4923



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 16/117 (13%)

Query: 159  SLAEIIGIARQLST---PQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGP 215
            S  +I+ + +Q S    P +Q     N  S+ D    S+ PPE      EP  P   + P
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYN-VSNLDVRQLSAPPPE------EPSPPPSPLAP 4923

Query: 216  SQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMES 272
            S     P +   E L ++ +  L  E P   P  L   P S + +  A PPE   +S
Sbjct: 4924 S-----PASPPTEPLVELPTEPLA-EPPVPSPLPLASSPESARPKPRARPPEEGEDS 4974



 Score = 31.2 bits (69), Expect = 4.4
 Identities = 33/175 (18%), Positives = 63/175 (36%), Gaps = 33/175 (18%)

Query: 228  ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287
            + L+ ++SS +  E P  +  LLE E   +Q++                     +QP  +
Sbjct: 3231 DELDKMESSLVASELPLLIEDLLEHEKKELQKKQQL---------------SAQLQPAQQ 3275

Query: 288  DQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
             Q      ++   P   +        +    + +QQ+  +      +P   Q   P +PP
Sbjct: 3276 QQQQQQQHSLLSAPGPAQAMSLPHEGSSPSLAGSQQQLSLGLAGARQPGLPQPLMPTQPP 3335

Query: 348  VSPMEHELS-----ISEQ----------QQPVQPSESSREVESSLTQQETPGQPP 387
               ++  L+     +S Q          Q  + P +SS+ V   L+Q+     PP
Sbjct: 3336 AHALQQRLAPSMAMVSNQGHMLSGQHGGQAGLVPQQSSQPV---LSQKPMGTMPP 3387


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 175/759 (23%), Positives = 286/759 (37%), Gaps = 141/759 (18%)

Query: 86   HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
            HLGP    E       P+   E+L   + T D    +  +P++         +K+  Q  
Sbjct: 955  HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006

Query: 143  LPVSP--KKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPS---SLPP 197
            + +SP  K + KD  + +   E     + L     +K+ +      + TP PS   SLP 
Sbjct: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPI------SITPPPSLQYSLPG 1060

Query: 198  ELRVKSDEPPGPSEQVGPSQFHLEPETQNPE-------TLEDIQSSSLQQEAPAQLPQLL 250
             L + S +P      + P Q      T  P+       TL   Q+  L      Q  Q L
Sbjct: 1061 ALPI-SGQPLTKCIHLTPQQAQEVGITLTPQQAQAQGITLTLQQAQELGIPLTPQQAQAL 1119

Query: 251  EEEPSSMQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVT 307
            E   +  Q +A   P  P ++ ++ +TL         P +DQA    P I++        
Sbjct: 1120 EILFTPQQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------- 1159

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPME-HELSISEQQQPVQP 366
                      ++Q  Q+  I       P   QQ   +  P++P +  EL I     P+ P
Sbjct: 1160 ----------TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTP 1197

Query: 367  SESSREVESSLTQQETP--GQP--PEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIA 422
             ++ + +  SLT Q+    G P  P+  +         Q   L  P    +   + +T+ 
Sbjct: 1198 QQA-QALRVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLT 1256

Query: 423  AEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQ 481
             +   E+G  L  Q+A A     G  + P   Q  G PL P+ ++  G PL  +Q  +  
Sbjct: 1257 PKQVQELGIPLTPQQAQAL----GITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALG 1312

Query: 482  SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEH 536
             P       P   Q       PQ A+  E +LT Q+A     P  T +   + +   P+H
Sbjct: 1313 IPF-----TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQH 1367

Query: 537  SH---LTQATVQPLDLGFTITPESMTEVELSPTMKE--------TPTQPPKKVVPQLRVY 585
            +    +   T Q  +LG  +TP+    + +  T ++        TP Q  +  +P     
Sbjct: 1368 AQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQ 1427

Query: 586  QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRT------IVSPK 639
                  T    QAQ    P    Q  +LG+T+TP+   E+G    P++       ++ P+
Sbjct: 1428 AQAQEITLTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQ 1487

Query: 640  HPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVT 699
              E+ +P   Q Q Q   +     Q  +LG  +TP      + + AL     PP   E+ 
Sbjct: 1488 AQELGIPLTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELG 1540

Query: 700  LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGL 753
            +P           LT   VQ L + L        E+  +P   +      T  Q  +LG+
Sbjct: 1541 IP-----------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGI 1589

Query: 754  AIIPEPTTETGHSTALEKTTAP----HPDRVQSLHRSLT 788
             + P+   E G     ++  A      P + Q+L  SLT
Sbjct: 1590 PLTPQQAQELGIPLTPQQAQAQGIPLTPQQAQALGISLT 1628



 Score = 60.8 bits (146), Expect = 5e-09
 Identities = 136/626 (21%), Positives = 239/626 (38%), Gaps = 117/626 (18%)

Query: 32   LLVKEAQPLEWVKDPLQLTSN--PLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGP 89
            L  ++AQ LE +  P Q  +   PL P ++     +  P++   AP +         LG 
Sbjct: 1111 LTPQQAQALEILFTPQQAQALGIPLTPQQTQVQGITLTPQQD-QAPGISLTTQQAQKLG- 1168

Query: 90   SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK 149
                 +P  PQ++    +P           PL P+Q  A +  L  + + +  +P++P++
Sbjct: 1169 -----IPLTPQQAQALGIPLTPQQAQELGIPLTPQQAQALRVSLTPQQAQELGIPLTPQQ 1223

Query: 150  LKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGP 209
                 AQ   +   +  A+QL  P + +Q        T TP                   
Sbjct: 1224 -----AQALGITLTLQQAQQLGIPLTPQQA--QALGITLTP------------------- 1257

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
             +QV      L P  Q  + L    +    QE    L       P   Q     L P+ +
Sbjct: 1258 -KQVQELGIPLTP--QQAQALGITLTPKQAQELGIPL------NPQQAQTLGIPLTPKQA 1308

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETE---SSQAQQETP 326
             ++L +P      Q  G       +P    +    E+T+T +         ++Q  QE  
Sbjct: 1309 -QALGIPFTPQQAQALG-------IPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELG 1360

Query: 327  IQF-PEEVE----PSATQQEAPIEPPVSPMEHE-----LSISEQQQ---PVQPSESSREV 373
            I   P+  +    P  TQQ   +  P++P + +     L+  + Q+   P+ P ++ +E+
Sbjct: 1361 IPLTPQHAQALGMPLTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQA-QEL 1419

Query: 374  ESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSL 433
                T Q+   Q     E+T++P    Q   L  P  + +  ++ +T+  + + E+G  L
Sbjct: 1420 GIPFTPQQAQAQ-----EITLTP---QQAQALGMPLTAQQAQELGITLTPQQAQELGIPL 1471

Query: 434  VHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
              Q+A A     G  + PP  Q  G PL P+ ++  G L +  +   +   P+    P  
Sbjct: 1472 TPQQAQAL----GIPLIPPQAQELGIPLTPQQAQALGILLIPPQAQ-ELGIPLT---PQQ 1523

Query: 494  TQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
             Q       P  A+E    LT Q+      P   P+   + +   P+ +           
Sbjct: 1524 AQALGIPLIPPQAQELGIPLTPQQVQALGIPLIPPQAQELEIPLTPQQAQA--------- 1574

Query: 549  LGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH-PVSPSVT 607
            LG  +TP+   E+ +  T    P Q  +  +P           TP Q QAQ  P++P   
Sbjct: 1575 LGIPLTPQQAQELGIPLT----PQQAQELGIPL----------TPQQAQAQGIPLTPQ-- 1618

Query: 608  VQLLDLGLTITPEPTTEVGHSTAPKR 633
             Q   LG+++TP+     G +  P++
Sbjct: 1619 -QAQALGISLTPQQAQAQGITLTPQQ 1643


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 193/902 (21%), Positives = 320/902 (35%), Gaps = 136/902 (15%)

Query: 61   SSHSSHFPRESPHAPTLPADPWDF-DHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQ 119
            + H    P  + +    PA+P +  +      ++  PA P E+ E       T      +
Sbjct: 421  TEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPV--E 478

Query: 120  PLEPEQFLASQQDLKDKLSPQE---RLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQ 176
            P E  +  A+++       P E   R P + +K     A+     E   +A + +TP   
Sbjct: 479  PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 538

Query: 177  KQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN----PETLED 232
            + T   E ++ +   PS  P E     D  P  +E+  PS   L   T+N    P   E 
Sbjct: 539  EPTENRERTANEKTTPS--PAEPTENGDRTPLANEKTTPS---LAEPTENGQRTPFANEK 593

Query: 233  IQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYY 292
              SSS +     +   L  E  +     +PA P E+  E     N   S   P E++   
Sbjct: 594  TTSSSAEPTEHEERTPLANENTTP----SPAEPTENR-ERTANENTTPSPAGPTENREMT 648

Query: 293  HLPNITVKPADVEVTITSEPTNETESSQAQQET--PIQFPEEVEPSATQQEAPIEPPVSP 350
                 T+ PA        EPT   E +  ++ T  P +  E  + +    E        P
Sbjct: 649  ANEKTTLFPA--------EPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEP 700

Query: 351  MEH--ELSISEQQQPVQPSESSREVESSLTQQETP--GQPPEHHEVTVS----PPGHHQT 402
             EH     ++ +   + P+E +   E +  ++ TP   +P E+ E T +    P     T
Sbjct: 701  TEHGERTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPT 760

Query: 403  HHLDSPSVSVKPPDVQLTIAAEPSAE-VGTSLVHQEATARLSGSGNDVEPPAIQHGGPPL 461
             + D   ++ +     L   AEP+     T   +++ T+  +      E   + +     
Sbjct: 761  ENGDRTPLANEKTTPSL---AEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTS 817

Query: 462  LP-ESSEEAGPLAVQQETSF-----QSPEPINNENPSPTQQEAAAEHPQTAEEGES---- 511
             P E +E     A ++ T F     ++ E   NE  +P   E       TA E  +    
Sbjct: 818  SPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPA 877

Query: 512  -SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVE---LSPTM 567
                H+E      E   +  A+P E+   T  T +        TP S    E    +P  
Sbjct: 878  EPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKT------TPSSAEPTEHGERTPLA 931

Query: 568  KETPTQPPKKVVPQL---RVYQGVTNPTP------GQDQAQHPVSPSVT--------VQL 610
             E  T  P +  P     R+      P+P      G+       +PS            L
Sbjct: 932  NEITT--PSRAEPTEHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPL 989

Query: 611  LDLGLTITPEPTTEVGHSTAPKRTIVSPKHP-----------EVTLPHPDQVQTQHSHLT 659
             +   T +P  +TE G  TA ++T  SP  P           E T+P P +  T+H  +T
Sbjct: 990  ANENTTTSPTESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAK-PTEHEEMT 1048

Query: 660  RATVQPLDLGFTITPKSMTEVEPSTAL----MTTAP--PPGHPEVTLPPSDK---GQAQH 710
             +  +      T +P   TE    T L    +T +P  P  H   T   ++K     A+ 
Sbjct: 1049 PSANE----NTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKP 1104

Query: 711  SHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALE 770
            +   + T  P D ++T +   +TE +   T+    T  P   +      T      T + 
Sbjct: 1105 TEHGERTTSPND-KITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVT 1163

Query: 771  KTTAPHPDRVQSLHRSLTEVTGPPTEL---------------EPAQDSLVQSESYTQN-- 813
            + +  HP++  S     T     PT                 E   ++L  +   T+   
Sbjct: 1164 EKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIK 1223

Query: 814  ---KALTAPEEQKASTSTNICELCTCGDEMLSCID--LNPEQRLRQVPVPEPNTHNGTFT 868
               K+   PE+  A T T    +   GD+ L+     LN  +   QVP        G+FT
Sbjct: 1224 APVKSTENPEKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKTEVTHQVP-------TGSFT 1276

Query: 869  IL 870
            ++
Sbjct: 1277 LI 1278



 Score = 77.4 bits (189), Expect = 5e-14
 Identities = 170/762 (22%), Positives = 264/762 (34%), Gaps = 108/762 (14%)

Query: 88   GPSASSEM---------PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
            GP+ + EM         PA P E  E       T   A  +P E  +  A++        
Sbjct: 341  GPTENREMTANENTTLFPAEPTEHGERTANENTTPSPA--EPTEHGERTANENTTPSPAE 398

Query: 139  PQE---RLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSL 195
            P E   R P +  K     A+     E   +A + +TP   + T   E ++ +   PS  
Sbjct: 399  PTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPA 458

Query: 196  -PPELRVKSDEPPGPSEQVGPSQFHL----EPETQNP-ETLEDIQSSSLQQE----APAQ 245
             P E R  +         V P++       E  T +P E  E+ Q +    E    + A+
Sbjct: 459  GPTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAE 518

Query: 246  LPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKPAD 303
              +  E  P + +   P+ P E +       N + +  P  P E+     L N    P+ 
Sbjct: 519  PTEHGERTPLANENTTPS-PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSL 577

Query: 304  VEVTITSEPT---NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
             E T   + T   NE  +S + + T     EE  P A +   P   P  P E+    + +
Sbjct: 578  AEPTENGQRTPFANEKTTSSSAEPTE---HEERTPLANENTTP--SPAEPTENRERTANE 632

Query: 361  QQPVQPSESSREVESSLTQQET--PGQPPEH-----HEVTVSPPGHHQTHHLDSPSVSVK 413
                 P+  +   E +  ++ T  P +P E+     +E T S P     +   +P  + K
Sbjct: 633  NTTPSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEK 692

Query: 414  PPD--VQLTIAAE--PSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEA 469
                  + T   E  P A   T+L   E T     + N+   P          P    E 
Sbjct: 693  TTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTANEKTTP---------FPAEPTEN 743

Query: 470  GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVV 529
                  + T+    +P  N + +P   E     P  AE  E+      A  +T       
Sbjct: 744  RERTANENTTPSPAQPTENGDRTPLANEKTT--PSLAEPTENGKRTPFANEKTTSSS--- 798

Query: 530  VAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVT 589
             A+P EH+  T    +      T +P   TE     T  E  TQ P +            
Sbjct: 799  -AEPTEHAERTPLANE----NTTSSPAEPTE-NRERTANEKTTQFPAE------------ 840

Query: 590  NPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPD 649
             PT  ++   +  +            T  P   TE    TA + T +SP  P     H +
Sbjct: 841  -PTENRESTANEKT------------TPFPAEPTENREWTANENTTLSPAEPT---EHEE 884

Query: 650  QVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT--APPPGHPEVTLP----PS 703
                 +   T +  +P + G   TP +  +  PS+A  T      P   E+T P    P+
Sbjct: 885  MTPLANEKTTLSPAEPTENGER-TPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPT 943

Query: 704  DKGQA-QHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTE 762
            + G+   +   T +  +P +   T   + TT     PT     T   +      P  +TE
Sbjct: 944  EHGERIANEKATPSPAKPTEHGETTVNEDTTPSSAEPTENGERTPLANENTTTSPTESTE 1003

Query: 763  TGHSTALEKTT------APHPDRVQSLHRSLTEVTGPPTELE 798
             G  TA EKTT        H +R  S +         PTE E
Sbjct: 1004 HGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKPTEHE 1045



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 145/697 (20%), Positives = 234/697 (33%), Gaps = 89/697 (12%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           R L    S           T T + +S   + + KS   P        + +      +  
Sbjct: 187 RPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEES 246

Query: 228 ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287
           E  ED +++    +   +  + ++E  S+ +       P          N+  S   P E
Sbjct: 247 EKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTE 306

Query: 288 DQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
           ++      N T+ PA        EP    E +  +   P           T  E     P
Sbjct: 307 NRERTANENTTLSPA--------EPIENRERTANENTAPFPAGPTENREMTANENTTLFP 358

Query: 348 VSPMEHELSISEQQQPVQPSESSREVESSLTQQET--PGQPPEH-------HEVTVSPPG 398
             P EH    + +     P+E +   E +  +  T  P +P EH       ++ T S   
Sbjct: 359 AEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 418

Query: 399 HHQTHHLDSP--SVSVKPPDVQLTIAAEPSAEVGTS------LVHQEATARLSGSGNDVE 450
               H   +P  + +  P   + T   E +A   T+        ++E TA    + + VE
Sbjct: 419 ESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 478

Query: 451 P------PAIQHGGP-PLLPESSEEAGPLAVQQETSFQSP-------EPINNENPSPTQQ 496
           P       A +   P P  P  + +  P A ++ TS  +         P+ NEN +P+  
Sbjct: 479 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 538

Query: 497 EAAAEHPQTAEE--GESSLTHQEAPAQTP---EFPNVVVAQPPEHSHLTQATVQPLDLGF 551
           E      +TA E    S     E   +TP   E     +A+P E+    Q T    +   
Sbjct: 539 EPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENG---QRTPFANEKTT 595

Query: 552 TITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL- 610
           + + E     E +P   E  T  P +   + R      N TP       P  P+   ++ 
Sbjct: 596 SSSAEPTEHEERTPLANENTTPSPAEPT-ENRERTANENTTPS------PAGPTENREMT 648

Query: 611 LDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLG- 669
            +   T+ P   TE    TA ++T  SP  P     +  +    +   T ++ +P + G 
Sbjct: 649 ANEKTTLFPAEPTENRERTANEKTTSSPAEP---TENGQRTPFANEKTTSSSAEPTEHGE 705

Query: 670 --------FTITPKSMTEVEPSTALMTTAPPPGHP---------EVTLP----PSDKGQ- 707
                    T++P   TE    TA   T P P  P         E T P    P++ G  
Sbjct: 706 RTPLANENTTLSPAEPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDR 765

Query: 708 --AQHSHLTQATVQPLD--LELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET 763
               +   T +  +P +         + TT     PT     T   +      P   TE 
Sbjct: 766 TPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTEN 825

Query: 764 GHSTALEKTT----APHPDRVQSLHRSLTEVTGPPTE 796
              TA EKTT     P  +R  + +   T     PTE
Sbjct: 826 RERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTE 862



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 116/520 (22%), Positives = 191/520 (36%), Gaps = 76/520 (14%)

Query: 50   TSNPLGPPESWSSHSSHFPRESPHAPT-------------LPADPWDFDHLGPSASSEMP 96
            T  P  P E+  S ++      P  PT              PA+P + + + P A+ +  
Sbjct: 835  TQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLANEKTT 894

Query: 97   APPQESTEN--LVPFLD--TWDSAGEQPLEPEQF-LASQQDLKDKLSPQER-LPVSPKKL 150
              P E TEN    PF +  T  S+ E     E+  LA++     +  P E    ++ +K 
Sbjct: 895  LSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEITTPSRAEPTEHGERIANEKA 954

Query: 151  KKDPAQRWSLAEIIGIARQLSTPQSQKQT-------LQNEYSSTDTPYPSSLPPELRVKS 203
               PA+     E      + +TP S + T       L NE ++T +P  S+   E     
Sbjct: 955  TPSPAKPTEHGET--TVNEDTTPSSAEPTENGERTPLANE-NTTTSPTESTEHGERTANE 1011

Query: 204  DEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPA 263
               P P+E   P++      + N +T+           +PA+  +  E  PS+ +   P+
Sbjct: 1012 KTTPSPAE---PTEHGERTPSANEKTI----------PSPAKPTEHEEMTPSANENTTPS 1058

Query: 264  -LPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKPADVEVTITSEPT---NETE 317
             + P    E  TL N ++++ P  P E  A     N  + P+  + T   E T   N+  
Sbjct: 1059 PVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITPSLAKPTEHGERTTSPNDKI 1118

Query: 318  SSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEH----ELSISEQQQPVQPSESSREV 373
            +S A + T      E    AT        P  P++H     L+  +  Q  + S    E 
Sbjct: 1119 TSSAAEST------EHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEK 1172

Query: 374  ESSLTQQ--ETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPD--VQLTIAAEPSAEV 429
             +S T++   TP +P  + E T+   G        +  V  KP +     T+  E     
Sbjct: 1173 TTSTTEKTTRTPEKPTLYSEKTICTKG-------KNTPVPEKPTENLGNTTLTTETIKAP 1225

Query: 430  GTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
              S  + E TA ++        P+++  G   L  +S       V  +    S   I + 
Sbjct: 1226 VKSTENPEKTAAVT----KTIKPSVKVTGDKSLTTTSSHLNKTEVTHQVPTGSFTLITSR 1281

Query: 490  NP-SPTQQEAAA--EHPQTAEEGESSLTHQEAPAQTPEFP 526
               S    EA     HP   ++G     H     +   FP
Sbjct: 1282 TKLSSITSEATGNESHPYLNKDGSQKGIHAGQMGENDSFP 1321



 Score = 41.2 bits (95), Expect = 0.004
 Identities = 69/332 (20%), Positives = 115/332 (34%), Gaps = 49/332 (14%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +             
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGK------------- 155

Query: 535 EHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG 594
              H+T A            P+S      S T K T T+   K    L       + T  
Sbjct: 156 --KHITPA------------PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTST 201

Query: 595 QDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH--STAPKRTIVSPKHPEVTLPHPDQVQ 652
                   S   T    + G + T + +T      + A K T  +   PE +    D   
Sbjct: 202 S-------SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRT 254

Query: 653 TQHSH--LTRATVQPLDLGFTITPKSMTE--VEPSTALMTTAPPPGHPEVTLPPSDKGQA 708
           T  S   LT+ T    ++  TI+   +T+   EP+     TA     P    P  ++ + 
Sbjct: 255 TVASDKLLTKTT---KNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERT 311

Query: 709 QHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTA 768
            + + T +  +P++       + T      PT  E      +    + P   TE G  TA
Sbjct: 312 ANENTTLSPAEPIENRERTANENTAPFPAGPT--ENREMTANENTTLFPAEPTEHGERTA 369

Query: 769 LEKTTAPHPDRVQSLHRSLTEVTGP----PTE 796
            E TT    +  +   R+  E T P    PTE
Sbjct: 370 NENTTPSPAEPTEHGERTANENTTPSPAEPTE 401



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 17/182 (9%)

Query: 638 PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE--PSTALMTTAPPPGH 695
           P+ P+ T  H  +     +  ++ T +P     TI  KS T+    P T+   ++     
Sbjct: 72  PELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKD 131

Query: 696 PEV----TLPPSD-----KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE--ET 744
           P +    ++ P+D     K  A   H+T A    ++   + T K T   K   T    E 
Sbjct: 132 PMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEK 191

Query: 745 STQPPDLGLAIIPEPTTE---TGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQ 801
           S    D       + TT    +G+S   +K+T+  P+++ +  ++  + TG P E E  +
Sbjct: 192 SMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS-FPEKITAASKTTYKTTGTPEESEKTE 250

Query: 802 DS 803
           DS
Sbjct: 251 DS 252


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 87.4 bits (215), Expect = 5e-17
 Identities = 171/797 (21%), Positives = 286/797 (35%), Gaps = 92/797 (11%)

Query: 58  ESWSSHSSHFPR--ESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDS 115
           ES S  ++ FP   E   +PT P                M  P +ES  + + F+ T   
Sbjct: 120 ESTSDSTTLFPSSTEDTSSPTTPE----------GTDVPMSTPSEESISSTMAFVST--- 166

Query: 116 AGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQS 175
           A     E    L  + D+   L+   +   SP   +     + + +E  G     S P S
Sbjct: 167 APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSE--GSTPLTSMPAS 224

Query: 176 QKQTLQNE-YSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPE------TQNPE 228
             +   +E  +   TP   S P  +  ++   P  +E  GPS  +  P       T+ P 
Sbjct: 225 TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE--GPSLSNSAPSGGSTPLTRMPL 282

Query: 229 TLEDIQSSSLQQ----EAPAQLPQLLEEEPSSMQQ--EAPALPPESSMESLT-LPNHEVS 281
           ++  + SS         A   +P +   E SS     E  ++P  +  E  T L +   S
Sbjct: 283 SVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAS 342

Query: 282 VQPPGEDQAYYHLPNITVKPADVE--VTITSEPTNETESSQAQQETPIQFPEEVEPSATQ 339
             P    +    +  +++ P D    VT ++EP++   +++A         E   P    
Sbjct: 343 TMPVATSE----MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM 398

Query: 340 QEAPIEPPVSPMEHELSISEQQQPV-----QPSESSREVESSLTQQETPGQ---PPEHHE 391
             + I    S      +I    +       + S S    E +     TP +   P     
Sbjct: 399 PVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAEDTSIATSTPSEGSTPLTSMP 458

Query: 392 VTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEP 451
           V+ +P    +  +L +  V  K    Q+T + E S+   T+ V+   T+  S     +  
Sbjct: 459 VSTTPVASSEASNLSTTPVDSK---TQVTTSTEASSSPPTAEVNSMPTSTPSEGSTPLTS 515

Query: 452 PAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGES 511
            ++       +P +S EA  L         S  P++   P  T  EA++    T  EG S
Sbjct: 516 MSVS-----TMPVASSEASTL---------STTPVDTSTPVTTSSEASSS--STTPEGTS 559

Query: 512 SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETP 571
             T   +   TP     V  +    S  +  +  P D    +T  S  E   S T  E  
Sbjct: 560 IPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSS--EASSSSTTAEGT 617

Query: 572 TQPPKK------VVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEV 625
           + P          +  + V   +   +     +  PV  +  V         T   TT  
Sbjct: 618 SMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTT---STEATSSSTTAE 674

Query: 626 GHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA 685
           G S  P  T      P  ++P    +       T +T  P+D    +T  +     P+TA
Sbjct: 675 GTSM-PTSTYTEGSTPLTSMPVNTTLVASSEASTLSTT-PVDTSTPVTTSTEASSSPTTA 732

Query: 686 ----LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTT 741
               + T+ P  G   +T  P  K     S  +  +  PLD    ITT  +TE   SPTT
Sbjct: 733 DGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT--STEASCSPTT 790

Query: 742 EETSTQP---PDLGLAIIPE-PTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTEL 797
            E ++ P   P  G  ++   P + T  ++    T +  P    S   + TEV+  PT  
Sbjct: 791 TEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSSPT-- 848

Query: 798 EPAQDSLVQSESYTQNK 814
            PA+ + + + +Y++ +
Sbjct: 849 -PAEGTSMPTSTYSEGR 864



 Score = 84.0 bits (206), Expect = 6e-16
 Identities = 166/802 (20%), Positives = 270/802 (33%), Gaps = 74/802 (9%)

Query: 71   SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQ 130
            S  +P L + P     +    +S +   P +S   ++    T       P+  E      
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVI----TSTEVSSSPIPTEGTSMQT 2153

Query: 131  QDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSS--TD 188
                D+ +P   +PVS   +        S   +       ++ +++     +E +S  T 
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 2213

Query: 189  TPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEP-ETQNPETLEDIQSSSLQQEAPAQLP 247
            TP   S P      S  P   SE    S     P +T  P T     +SS        +P
Sbjct: 2214 TPSEGSTPFTSMPVSTMPVVTSEA---STLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 248  QLLEEEPSSMQQEAPA---LPPESSMESL-TLP---------NHEVSVQPPGEDQAYYHL 294
                 E ++     P    L   S + +L T P         + E S  PP  +     +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT--SM 2328

Query: 295  PNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
            P  T    +  +T        + S  T+   ++ A   TP+    +   S T  +    P
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 347  PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLD 406
              +  E    ++       P  SS     S T  +T        E + SP     T    
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448

Query: 407  SPSVSVKPPDVQLTIAAEP--SAEVGT-----------SLVHQEATARLSGSGNDVEPPA 453
            SP      P   + ++  P  S+E GT                EA++  + + + V P +
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508

Query: 454  IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513
                G  LL        P+A   E S  S  P+++ +P  T  E ++    T+ EG S  
Sbjct: 2509 TASEGSTLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTSMP 2565

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQ 573
            T   +   TP     V  +P   S  +  +  P+D    +T  + TE   SPT  +  + 
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT--TSTETSSSPTTAKDTSM 2623

Query: 574  P---PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTA 630
            P   P +V   L      T P    + +    +P  T  L+      +  PTT  G S+ 
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEG-SSM 2682

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA----L 686
            P  T      P   +     +       T +T  P+D    +T  +     P+TA    +
Sbjct: 2683 PTSTPGERSTPLTNILVSTTLLANSEASTLSTT-PVDTSTPVTTSAEASSSPTTAEGTSM 2741

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETST 746
              + P  G   +T           S  +  +   +D  + +TT  +TE   SPTT E ++
Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT--STEASSSPTTAEVTS 2799

Query: 747  QPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQ 806
             P            T T   T+   T+ P      +   + T  T P     P   S   
Sbjct: 2800 MP------------TSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKA 2847

Query: 807  SESYTQNKALTAPEEQKASTST 828
            S S T  + +  P    +  ST
Sbjct: 2848 SSSPTTAEGIVVPISTASEGST 2869



 Score = 80.5 bits (197), Expect = 6e-15
 Identities = 139/699 (19%), Positives = 235/699 (33%), Gaps = 61/699 (8%)

Query: 165  GIARQLSTPQSQKQTLQNEYSST------------DTPYPSSLPPELRVKSDEPPGPSEQ 212
            G +  +STP  ++  L +   ST             TP  +S P     ++   P  +E 
Sbjct: 2974 GTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAEG 3033

Query: 213  VGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMES 272
             G     +   ++    L  I  S+     P  +P+      + +   +P +   + + S
Sbjct: 3034 TG---IPISTPSEGSTPLTSIPVST----TPVAIPEASTLSTTPVDSNSPVVT-STEVSS 3085

Query: 273  LTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEE 332
               P    S+      +    L  + V    V    TS   +   ++     TP+    E
Sbjct: 3086 SPTPAEGTSMPISTYSEGSTPLTGVPVSTTPV----TSSAISTLSTTPVDTSTPVTTSTE 3141

Query: 333  VEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEV 392
               S T  E    P  +P E    ++          SS +   S T  +T        E 
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201

Query: 393  TVSPPGHHQTHHLDSPSVSVKP----PDVQLTIAAEPSAEVGTSLVHQEATARLSGSGND 448
            T S      +    +PS  + P    P     +A+  ++ + T+ V        S   + 
Sbjct: 3202 TSSTTAEGTSIPTSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTSTEASS 3261

Query: 449  VEPPAIQHGGPPLLPESSEEAGPL---------AVQQETSFQSPEPINNENPSPTQQEAA 499
              P A     P   P  SE + PL             ETS  S  P +   P  T  +A+
Sbjct: 3262 SPPTAEGTSMPTSTP--SEGSTPLTSMPVSTTTVASSETSTLSTTPADTSTPVTTYSQAS 3319

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMT 559
            +  P    +G S  T   +   TP         P   S  +  +  P+D    +T  + T
Sbjct: 3320 SSPP--IADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLSTTPVDTSTPVT--TST 3375

Query: 560  EVELSPTMKE---TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
            E  LSPT  E    PT  P +    L      T P    +      +P  +  L+     
Sbjct: 3376 EASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTTPVVSSEVNTLSTTPVDSNTLVTTSTE 3435

Query: 617  ITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
             +  PT   G ++ P  T      P   +P         S  +  +  P+D    +T  S
Sbjct: 3436 ASSSPTIAEG-TSLPTSTTSEGSTPLSIMP-LSTTPVASSEASTLSTTPVDTSTPVTTSS 3493

Query: 677  MTEVEPSTALMTTAPP----PGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
             T   P+TA +T+ P      G   +T  P        S  +  +  P+D    +T+  +
Sbjct: 3494 PTNSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEASTLSTTPVDSNTFVTS--S 3551

Query: 733  TEVKPSPTTEETST---QPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTE 789
            ++   SP T + +T     P  G + +      + + T+ E +T   P    S+ RS   
Sbjct: 3552 SQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTP----SVDRSTPV 3607

Query: 790  VTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTST 828
             T   +   P    ++     T ++  T       ST++
Sbjct: 3608 TTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTS 3646



 Score = 77.8 bits (190), Expect = 4e-14
 Identities = 164/680 (24%), Positives = 232/680 (34%), Gaps = 78/680 (11%)

Query: 165  GIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G + Q STP  +   L     ST     S    E    S  P     QV  S      E 
Sbjct: 2031 GTSIQTSTPSERTTPLAGMPVSTTLVVSS----EGNTLSTTPVDSKTQVTNST-----EA 2081

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLT--------LP 276
             +  T E    SS+   AP++   LL   P S     P   PE+S  S T        + 
Sbjct: 2082 SSSATAE---GSSMTISAPSEGSPLLTSIPLST---TPVASPEASTLSTTPVDSNSPVIT 2135

Query: 277  NHEVSVQP-PGEDQAYYHLPNITVKPADVEVTITSEPTNET----------ESSQAQQET 325
            + EVS  P P E  +       T   +D    +TS P + T           ++     T
Sbjct: 2136 STEVSSSPIPTEGTSMQ-----TSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTST 2190

Query: 326  PIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQ 385
            P+    E   S T  E    P  +P E     +       P  +S     S T  +T   
Sbjct: 2191 PVTNSTEARSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMPVVTSEASTLSATPVDTSTP 2250

Query: 386  PPEHHEVTVSPPGHH----QTHHLDSPSVSVKPPDVQLTIAAEPSAEVGT-SLVHQEATA 440
                 E T SP         T  L   +  +    V  T+ A  ++EV T S    ++  
Sbjct: 2251 VTTSTEATSSPTTAEGTSIPTSTLSEGTTPLTSIPVSHTLVA--NSEVSTLSTTPVDSNT 2308

Query: 441  RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPL---------AVQQETSFQSPEPINNENP 491
              + S     PP    G       SSE   PL             ETS  S  P +   P
Sbjct: 2309 PFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTP 2368

Query: 492  SPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF 551
              T  +A +  P TA++  S  T   +   TP     V   P   S  +  +  P+D   
Sbjct: 2369 VTTYSQAGSS-PTTADD-TSMPTSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTST 2426

Query: 552  TITPESMTEVELSPTMKE---TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV 608
             +T  + TE   SPT  E    PT PP +    L      T P    +      +P  T 
Sbjct: 2427 PVT--TSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTS 2484

Query: 609  QLLDLGLTITPEPTTE----VGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ 664
              +      +  PTT     V  STA + + +    P  T P      +  S     +  
Sbjct: 2485 TPMTTSTEASSSPTTAEDIVVPISTASEGSTLLTSIPVSTTPVASPEASTLSTTPVDSNS 2544

Query: 665  PLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
            P+     I+  S T  E ++   +T      P  ++P S K  A     T +T  P+D  
Sbjct: 2545 PVVTSTEIS-SSATSAEGTSMPTSTYSEGSTPLRSMPVSTKPLASSEASTLSTT-PVDTS 2602

Query: 725  LTITTKPTTEVKPSPTTEETSTQP------PDLGLAIIPEPTTETGHSTALEKTTAPHPD 778
            + +TT  +TE   SPTT + ++ P          L  I   T     S A   +T P   
Sbjct: 2603 IPVTT--STETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDT 2660

Query: 779  RVQSLHRSLTEVTGPPTELE 798
            R  +L  + T  +  PT  E
Sbjct: 2661 R--TLVTTSTGTSSSPTTAE 2678



 Score = 75.1 bits (183), Expect = 3e-13
 Identities = 152/718 (21%), Positives = 239/718 (33%), Gaps = 74/718 (10%)

Query: 170  LSTPQSQKQTL--QNEYSSTDTP-----YPSSLPPELRVKSDEPPGPSEQVGPSQFHLEP 222
            L+TP   K  +   NE SS+ TP      P+S   E R      P  +  V  S   +  
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILS 1358

Query: 223  ET----QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAP-ALPPESSMESLTLPN 277
             T      P T      SS        +P     E ++     P +  P  S E+ TL  
Sbjct: 1359 TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSA 1418

Query: 278  HEVSVQPPGEDQAYYHLPNITVK--------PADVEVTITSEPTNETESSQAQQETPIQF 329
              V    PG   A       T +        P++ +  + S P + T  + ++  T    
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478

Query: 330  PEEVEPSATQQEAPIEPPVSPMEHELSISEQQQ--------PVQPSE-SSREVESSLTQQ 380
            P +         A    P       ++IS   +        PV  +  +S E+ S  T  
Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTP 1538

Query: 381  ETPGQPPEHHEVTVSPPG-------HHQTHHLDSPSVSVKPPDVQLTIAAEP-------- 425
                 P   +    S P           T+   S  ++  P    L +++E         
Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598

Query: 426  -SAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
             S    T+     ++    GS   +  P+    G PLL        P+A   E S  S  
Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPS---EGSPLLTSIPVSTTPVA-SPEASTLSTT 1654

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            P+++ +P  T  E ++    T  EG S  T      +TP     V   P   S ++  + 
Sbjct: 1655 PVDSNSPVITSTEVSSS--PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 545  QPLDLGFTITPESMTEVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             P+D    +T  + TE   SPT  E  + P   P +    L      T P    + +   
Sbjct: 1713 TPVDNSTPVT--TSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRA 661
             +P  T   +      T  PTT  G S  P  T+     P  + P        +S  +  
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSI-PTSTLSEGMTPLTSTP-VSHTLVANSEASTL 1828

Query: 662  TVQPLDLGFTITPKSMTEVEPSTALMTT-APPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P+D        S + V  STA+ ++  P  G    T  PS+   A  S     T   
Sbjct: 1829 STTPVD--------SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA 1880

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGH---STALEKTTAPHP 777
                 T++T P     P  T  + S+ P     + +P  T   G    ++    TT    
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940

Query: 778  DRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCT 835
              + +L  +L +   P T    A  S   ++      ++  P   + ST      L T
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSSPTTAD----GTSMPTPAYSEGSTPLTSMPLST 1994



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 140/709 (19%), Positives = 232/709 (32%), Gaps = 84/709 (11%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            +TP +  +      +  D+  P     E+   +    G S           P    P + 
Sbjct: 2524 TTPVASPEASTLSTTPVDSNSPVVTSTEISSSATSAEGTSMPTSTYSEGSTPLRSMPVST 2583

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSME-------SLTLPNHEVSVQ 283
            + + SS     +   +   +    S+    +P    ++SM        S +L +  VS  
Sbjct: 2584 KPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAKDTSMPISTPSEVSTSLTSILVSTM 2643

Query: 284  PPGEDQAYYHLPNITVKPADVEVTIT-SEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
            P    +A      ++  P D    +T S  T+ + ++      P   P E     T    
Sbjct: 2644 PVASSEA----STLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTSTPGERSTPLTN--- 2696

Query: 343  PIEPPVSPMEHELSISEQQQPVQ---PSESSREVESSLTQQE-------TPGQ---PPEH 389
             I    + + +  + +    PV    P  +S E  SS T  E       TP     P   
Sbjct: 2697 -ILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSMRISTPSDGSTPLTS 2755

Query: 390  HEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDV 449
              V+  P    +   + + +V    P   +T + E S+   T+ V    T+  S +   +
Sbjct: 2756 ILVSTLPVASSEASTVSTTAVDTSIP---VTTSTEASSSPTTAEVTSMPTSTPSETSTPL 2812

Query: 450  EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEG 509
                + H      P +S EAG L+     +          + SPT  E       TA EG
Sbjct: 2813 TSMPVNH-----TPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAEGIVVPISTASEG 2867

Query: 510  ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKE 569
             + LT    P  T          P   S  +  +  P+D    +T  + TE   SPT  E
Sbjct: 2868 STLLT--SIPVST---------TPVASSEASTLSTTPVDTSIPVT--TSTEGSSSPTTAE 2914

Query: 570  TPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVG 626
              + P   P +V   L      T P  G + +    +P  T   +      +  PTT  G
Sbjct: 2915 GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVTTSAEASSSPTTAEG 2974

Query: 627  HSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA- 685
              T+   +    +   +T      +    S  +  +  P D    +T  +     P+TA 
Sbjct: 2975 --TSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPTTAE 3032

Query: 686  ---LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE 742
               +  + P  G   +T  P           +  +  P+D    + T  +TEV  SPT  
Sbjct: 3033 GTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVT--STEVSSSPTPA 3090

Query: 743  ETSTQP---------PDLGLAIIPEPTTETGHS--------------TALEKTTAPHPDR 779
            E ++ P         P  G+ +   P T +  S              T+ E  ++P    
Sbjct: 3091 EGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTPVDTSTPVTTSTEAHSSPTTSE 3150

Query: 780  VQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTST 828
              S+  S       P    P    LV S   +   A         +TST
Sbjct: 3151 GTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTST 3199



 Score = 63.9 bits (154), Expect = 6e-10
 Identities = 124/584 (21%), Positives = 202/584 (34%), Gaps = 69/584 (11%)

Query: 267  ESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETP 326
            E+S    T     + +  P E       P +T  P  +   +TS   +   ++     +P
Sbjct: 783  EASCSPTTTEGTSMPISTPSEGS-----PLLTSIPVSI-TPVTSPEASTLSTTPVDSNSP 836

Query: 327  IQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQ---------------PSESSR 371
            +    EV  S T  E    P  +  E    ++    PV                P ++S 
Sbjct: 837  VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSM--PVSTTLVATSAISTLSTTPVDTST 894

Query: 372  EVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQL-TIAAEPSAEVG 430
             V +S   + +P    E   +  S PG   T     P  +      +  T++A P     
Sbjct: 895  PVTNSTEARSSP-TTSEGTSMPTSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPVDTST 953

Query: 431  TSLVHQEATAR-LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
                  EAT+   +  G  +       G  PL   S+  +  L    E S  S  P+++ 
Sbjct: 954  PVTTSTEATSSPTTAEGTSIPTSTPSEGTTPLT--STPVSHTLVANSEASTLSTTPVDSN 1011

Query: 490  NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDL 549
             P  T  EA++  P    EG S  T   +   TP                   T  P+  
Sbjct: 1012 TPLTTSTEASS--PPPTAEGTSMPTSTPSEGSTP------------------LTRMPVST 1051

Query: 550  GFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-----VSP 604
                + E+ T +  +P    TP     +         G + PT    +   P     VS 
Sbjct: 1052 TMVASSETST-LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVST 1110

Query: 605  SVTVQLLDLGLTITPEPTT-EVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
             + V      L+ TP  T+  V  ST    +  + +   +    P +  T  + +  +T 
Sbjct: 1111 RLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLASMPVSTT 1170

Query: 664  QPLDLGFTITPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
              L +       S T V+  T + T+    +PPP     ++P S  G+ + + LT   V+
Sbjct: 1171 --LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE-RSTPLTSMPVR 1227

Query: 720  PLDLEL----TITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
               +      T++T P     P  T+ ETS+ P       +P  TT  G ST L  T+ P
Sbjct: 1228 HTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG-STLL--TSIP 1284

Query: 776  HPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
                + +   + T +T P     P   S   S S T  +  + P
Sbjct: 1285 VSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 75/352 (21%), Positives = 129/352 (36%), Gaps = 38/352 (10%)

Query: 477 ETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
           E+S  S  P +++   +PT+    +E    +     S T   +   TPE  +V ++ P E
Sbjct: 95  ESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE 154

Query: 536 HS-HLTQATVQPLDL-------GFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQG 587
            S   T A V    L         T   +  T +  S     +PT P    +P+    +G
Sbjct: 155 ESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEG 214

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPH 647
            T P      +   V+ S  + LL   + I+   T     S++P     + + P ++   
Sbjct: 215 ST-PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSP----TTAEGPSLSNSA 269

Query: 648 PDQVQTQ------------HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
           P    T              S  +  +  P      +   +     P+TA  T+ P   +
Sbjct: 270 PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTY 329

Query: 696 PEVTLP----PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
            E + P    P+       S ++  ++ P+D    +TT  +TE    PTT E ++     
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTT--STEPSSLPTTAEATSMLTST 387

Query: 752 GLAIIPEPTTETGHSTAL-----EKTTAPHPDRVQSLHRSLTEVTGPPTELE 798
            L+    P T    ST L       TT+  P   ++   + +E +  PT  E
Sbjct: 388 -LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 135/631 (21%), Positives = 210/631 (33%), Gaps = 93/631 (14%)

Query: 260  EAPALPPESSMESLT-LPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETES 318
            E  ++P  ++ E  T L N  VS  P    +A      ++  P D    +TS       S
Sbjct: 3503 EVTSMPTSTAGEGSTPLTNMPVSTTPVASSEA----STLSTTPVDSNTFVTS-------S 3551

Query: 319  SQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSI-----SEQQQPVQPSESSREV 373
            SQA        P  ++ +  +   P E   S     LS      SE   P  PS      
Sbjct: 3552 SQASSS-----PATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSEASTPSTPSVDRSTP 3606

Query: 374  ESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSP----SVSVKPPDVQLTIAAEPSAEV 429
             ++ TQ  +   PPE   + +S P    T     P    SV++       T+  + S  V
Sbjct: 3607 VTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPV 3666

Query: 430  GTSLVHQEATARLSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSPEPIN 487
             TS     +     G+   +  P+   G  PL  +P S+          E S  S   + 
Sbjct: 3667 ITSTQVSSSPVTPEGTTMPIWTPS--EGSTPLTTMPVSTTRV----TSSEGSTLSTPSVV 3720

Query: 488  NENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
               P  T  EA +         +S+      P +       ++      +   +++   +
Sbjct: 3721 TSTPVTTSTEAISSSATL----DSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSI 3776

Query: 548  DLGFT-ITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSV 606
               +T ++  + +E   SPT  E  T  P     +          +P    +    S   
Sbjct: 3777 PSVYTSMSMTTASEGSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPSEASTLS 3836

Query: 607  TVQLLDLGLTITPEPT-TEVGHSTAPKR------TIVSPKH-PEVTLPHPDQVQTQHSHL 658
            T      G T TP  T T+ G  + P        +I S +  P  TL     + T     
Sbjct: 3837 TPP----GDTSTPLLTSTKAGSFSIPAEVTTIRISITSERSTPLTTLLVSTTLPTSFPGA 3892

Query: 659  TRATVQPLDLGFTITPKSMTEVEP--------STALMTTAPPPG------HPEVTLPPSD 704
            + A+  PLD   T TP + T   P        S +++T    PG         VT   +D
Sbjct: 3893 SIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTAD 3952

Query: 705  KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQPPDLGLAIIPEPT 760
               A    ++   +   +L    T+  +T    S T E T    +T  P   + +   P+
Sbjct: 3953 VFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPS 4012

Query: 761  TE-------TGHSTALEKTTAPH-----------PDRVQSLHRSLTEVTGPPTELEPAQD 802
            T        T  ++ L  T+ PH           P    S   ++T  T PPT   PA  
Sbjct: 4013 TPRTTSRGCTTSASTLSATSTPHTSTSVTTRPVTPSSESSRPSTITSHTIPPT-FPPAHS 4071

Query: 803  SL-----VQSESYTQNKALTAPEEQKASTST 828
            S        S +       T     K ST T
Sbjct: 4072 STPPTTSASSTTVNPEAVTTMTTRTKPSTRT 4102


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 84.3 bits (207), Expect = 4e-16
 Identities = 99/425 (23%), Positives = 149/425 (35%), Gaps = 57/425 (13%)

Query: 382  TPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATAR 441
            +PG PP           H  T     P    +PP    T  A P+   G S         
Sbjct: 969  SPGSPPTLRV-------HGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS--------- 1012

Query: 442  LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP--TQQEAA 499
               S     P         L P S+  +   +   +TS  +P+P +  NP    T  + A
Sbjct: 1013 --ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFA 1070

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMT 559
               P ++     +LT + +P   P  P  + + P   S +T  +          T E + 
Sbjct: 1071 LSTPDSSVV--PALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSP---------TSEQVP 1119

Query: 560  EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
            E + +P +  TP          +  Y    +P+P       P        +  L  T+TP
Sbjct: 1120 ESDTTPDLDTTPYSST------VSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTP 1173

Query: 620  EPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE 679
               T    +T P  T ++       +P P       + +T +T+ P     T TP+  T 
Sbjct: 1174 HFPTTPHPTTTPHPTTITHS---TMIPDPTTTPQPFTTITHSTMIPDP---TTTPQPFTT 1227

Query: 680  VEPSTALMTTAPPPG---HPEV----TLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
            ++P+T   +T P P    HP      T+ P      Q     Q T  P     T T  PT
Sbjct: 1228 MQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMP---HPTTTPHPT 1284

Query: 733  TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTG 792
            T   P+ T   T+T  P +     P+PTT    +T  + TT PHP         +     
Sbjct: 1285 TTPHPTTTPHPTTTPHPTM----TPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTVS 1340

Query: 793  PPTEL 797
             PT L
Sbjct: 1341 LPTSL 1345



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 129/567 (22%), Positives = 190/567 (33%), Gaps = 80/567 (14%)

Query: 165  GIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G  R   +P + +  +  +  S   P+P   PP        PP PS     S     P  
Sbjct: 965  GTTRSPGSPPTLR--VHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPAL 1022

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV--SV 282
             +  + E    S+L  EA +  P      P    +  P L   S   +L+ P+  V  ++
Sbjct: 1023 TSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPAL 1082

Query: 283  QPPGEDQAYYHLP-NITVKPAD----VEVTITSEPTNETESSQAQQETPIQFPEEVEPSA 337
             P         LP  +T  P+       ++ TSE   E++++     TP         S+
Sbjct: 1083 TPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPY--------SS 1134

Query: 338  TQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP 397
            T  E    P  SP  H  +  +      P        ++L    TP  P   H  T +P 
Sbjct: 1135 TVSEYSRSPDPSPSPHPTTTPDPTMAPDPI-------TTLNPTVTPHFPTTPHP-TTTPH 1186

Query: 398  GHHQTHHLDSPSVSVKPPD----VQLTIAAEPSAEVGTSLVHQEATARLSGSGNDV---E 450
                TH    P  +  P         T+  +P+         Q  T   S + +      
Sbjct: 1187 PTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPH 1246

Query: 451  PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGE 510
            P  I H    ++P+ +    P    Q T+   P P    +P+ T       HP T     
Sbjct: 1247 PTTITHS--TMIPDPTTTPQPFTTMQPTTM--PHPTTTPHPTTTPHPTTTPHPTTTPHP- 1301

Query: 511  SSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKET 570
               T    P  TP +P      P    H T        +  T++  +    ELS     +
Sbjct: 1302 ---TMTPDPTTTP-YP-TTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELS-----S 1351

Query: 571  PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTA 630
            PT  P  V P L      T P P    +Q P              T+ P P  E   S +
Sbjct: 1352 PTLAP-TVKPSLHPQLTFTAPAPHTSTSQIP--------------TLEPSPALESSPSRS 1396

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE--VEPSTALMT 688
               T + P   E   P     ++Q  +LT           T TP S ++  V P   L  
Sbjct: 1397 STATSMDPLSTEDFKP----PRSQSPNLTPPP--------THTPHSASDLTVSPDPLLSP 1444

Query: 689  TAPPPGHP---EVTLPPSDKGQAQHSH 712
            TA P  HP    +TL P+  GQ+   H
Sbjct: 1445 TAHPLDHPPLDPLTLGPT-PGQSPGPH 1470



 Score = 54.7 bits (130), Expect = 4e-07
 Identities = 118/585 (20%), Positives = 183/585 (31%), Gaps = 115/585 (19%)

Query: 56   PPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPP--QESTENLVPFLD-- 111
            P + W       P  +  AP  P+        GPSAS   P P    +S+  L P     
Sbjct: 985  PRKPWPERRPPRPAATRTAPPTPSP-------GPSASPGPPGPALTSDSSRELTPHSALT 1037

Query: 112  ---TWDSAGEQPLEPEQFLASQQDL----------------KDKLSPQER---LPVSPKK 149
               T D+    P  P+    +  DL                   L+P+     LP  PK+
Sbjct: 1038 SEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKE 1097

Query: 150  LKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGP 209
            L  DP+    +  +   + Q+    +        YSST + Y  S  P         P P
Sbjct: 1098 LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP------SPSPHP 1151

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
            +    P+       T NP       ++      P          P+++        P ++
Sbjct: 1152 TTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTP---------HPTTITHSTMIPDPTTT 1202

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
             +  T   H   +  P         P  T++P     + T  PT     +     T I  
Sbjct: 1203 PQPFTTITHSTMIPDPTTTPQ----PFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPD 1258

Query: 330  PEEV-EPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPE 388
            P    +P  T Q   +  P +             P      +     + T   T    P 
Sbjct: 1259 PTTTPQPFTTMQPTTMPHPTT----------TPHPTTTPHPTTTPHPTTTPHPTMTPDPT 1308

Query: 389  HHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGND 448
                  + P    T H  +P  S  P    +T  + P++ +GT L               
Sbjct: 1309 TTPYPTTTPDPTTTPHPTTPDPSSTP---VITTVSLPTS-LGTEL--------------- 1349

Query: 449  VEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEE 508
                      P L P       P     + +F +P P  + +  PT + + A     +  
Sbjct: 1350 --------SSPTLAPTVKPSLHP-----QLTFTAPAPHTSTSQIPTLEPSPA---LESSP 1393

Query: 509  GESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMK 568
              SS      P  T +F        P  S     T  P     T TP S +++ +SP   
Sbjct: 1394 SRSSTATSMDPLSTEDF-------KPPRSQSPNLTPPP-----THTPHSASDLTVSPDPL 1441

Query: 569  ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP--VSPSVTVQLL 611
             +PT  P    P   +  G   PTPGQ    H   V+P+  V+++
Sbjct: 1442 LSPTAHPLDHPPLDPLTLG---PTPGQSPGPHGPCVAPTPPVRVM 1483


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 141/594 (23%), Positives = 201/594 (33%), Gaps = 80/594 (13%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
            P  +  T T  PT    S+Q+   TPI     V P+ T       P  +P+    +++  
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 1371

Query: 361  QQPV---QPSESSREVESSLTQQETP--GQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPP 415
              P     P+ +     +++T   TP   Q P    +T +           + + +  P 
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTTTPI 1431

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQ 475
                T+   P+   GT      A    S       P   Q   P   P ++         
Sbjct: 1432 TTTTTVTPTPT-PTGTQAPTPTAITTTSTVTPTPTPTGTQ--TPTTTPITT--------- 1479

Query: 476  QETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
              T   +P P   + P+PT     A    T      + T  + P  TP      V   P 
Sbjct: 1480 TTTVTPTPTPTGTQTPTPT-----AITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPT 1534

Query: 536  HSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
             +     T  P+    T+TP        +PT  +TPT  P               PTP  
Sbjct: 1535 PTGTQTPTPTPISTTTTVTPTP------TPTGTQTPTTTPITTTT-------TVTPTPTP 1581

Query: 596  DQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTL---PHPDQVQ 652
               Q P     T  L+    T+TP PT      T+ K T V+P     T+   P P   Q
Sbjct: 1582 TGTQTP-----TTVLITTTTTMTPTPT-----PTSTKSTTVTPITTTTTVTATPTPTGTQ 1631

Query: 653  TQH----SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA 708
            T      S  T  T  P     +  P + T   P   L T+ PP   PE + P + +  +
Sbjct: 1632 TPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP---PESSTPQTSRSTS 1688

Query: 709  QHSHLTQAT----VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETG 764
              S LT++T      P  +E+T T  P+T   P+ T+   +  PP       P  T   G
Sbjct: 1689 --SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-STTTSPPGTPTRG 1745

Query: 765  HSTALEKTTAPHPDRVQSLHRSLTEVTGPP---------TELEPAQDSLVQSESYTQNKA 815
             +T    ++AP P  VQ+   S    T  P         T L P   S++       N  
Sbjct: 1746 TTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--ICCVLNDT 1801

Query: 816  LTAP-EEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
              AP EE    T  + C    C    LSC            P P P     T T
Sbjct: 1802 YYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCPSTPSPTPTPSKSTPT 1852



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 95/389 (24%), Positives = 127/389 (32%), Gaps = 61/389 (15%)

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQ 573
            T  E P  TP      V   P  +     T  P+    T+TP        +PT  +TPT 
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP------TPTGTQTPTT 1359

Query: 574  PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKR 633
             P               PTP     Q P +  +T        T+TP P T  G  T P  
Sbjct: 1360 TPITTTT-------TVTPTPTPTGTQTPTTTPITTT-----TTVTPTP-TPTGTQT-PTS 1405

Query: 634  TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP---KSMTEVEPSTALMTTA 690
            T ++        P P   QT        T  P+    T+TP    + T+    TA+ TT+
Sbjct: 1406 TPITTTTTVTPTPTPTGTQT-------PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTS 1458

Query: 691  -------PPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE 743
                   P       T P +       +     T  P    +T TT  T    P+ T   
Sbjct: 1459 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP 1518

Query: 744  TSTQPPDLGLAIIPEPT-------TETGHSTALEKTTAPHPDRVQSLH----RSLTEVTG 792
            TST P      + P PT       T T  ST    T  P P   Q+       + T VT 
Sbjct: 1519 TST-PITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1577

Query: 793  PPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCT-------CGDEMLSCID 845
             PT       + V   + T       P   K++T T I    T        G +  + I 
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637

Query: 846  LNPEQRLRQVPVPE-----PNTHNGTFTI 869
            ++    +   P P      P TH  T  I
Sbjct: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPI 1666



 Score = 39.7 bits (91), Expect = 0.012
 Identities = 94/494 (19%), Positives = 150/494 (30%), Gaps = 98/494 (19%)

Query: 165  GIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G     +TP +   T+    + T T  P+S P          P P+    P+     P T
Sbjct: 1376 GTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT---TPIT 1432

Query: 225  QNPETLEDIQSSSLQQEAPAQLP--QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV 282
                       +  Q   P  +     +   P+    + P   P ++  ++T        
Sbjct: 1433 TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1492

Query: 283  QPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
            Q P               P  +  T T  PT     +Q    TPI     V P+ T    
Sbjct: 1493 QTP--------------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1538

Query: 343  PIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSP---PGH 399
                P +P+    +++    P              T  +TP   P     TV+P   P  
Sbjct: 1539 QTPTP-TPISTTTTVTPTPTP--------------TGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 400  HQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGP 459
             QT     P+  +      +T    P++   T++     T  ++ +     P       P
Sbjct: 1584 TQT-----PTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT-----PTPTGTQTP 1633

Query: 460  PLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAP 519
             ++P S+           T   +P P       PT       H  TA   E + ++    
Sbjct: 1634 TMIPIST---------TTTVTPTPTPTTGSTGPPT-------HTSTAPIAELTTSNPPPE 1677

Query: 520  AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVV 579
            + TP+               +++T  PL    T+         L P ++ T T PP    
Sbjct: 1678 SSTPQ--------------TSRSTSSPLTESTTLLS------TLPPAIEMTSTAPPS--- 1714

Query: 580  PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPK 639
                     T   P      H +SP  +      G   TP   T  G S+AP  + V   
Sbjct: 1715 ---------TPTAPTTTSGGHTLSPPPSTTTSPPG---TPTRGTTTGSSSAPTPSTVQTT 1762

Query: 640  HPEVTLPHPDQVQT 653
                  P P  + T
Sbjct: 1763 TTSAWTPTPTPLST 1776



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 54/249 (21%), Positives = 82/249 (32%), Gaps = 14/249 (5%)

Query: 298  TVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQ--QEAP----IEPPVSPM 351
            T  P  +  T T  PT     +Q    TPI     V P+ T    + P    I    +  
Sbjct: 1540 TPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTVLITTTTTMT 1599

Query: 352  EHELSISEQQQPVQPSESSREVESSLTQ--QETPGQPPEHHEVTVSPPGHHQTHHLDSPS 409
                  S +   V P  ++  V ++ T    +TP   P     TV+P     T     P+
Sbjct: 1600 PTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIPISTTTTVTPTPTPTTGSTGPPT 1659

Query: 410  VSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGN--DVEPPAIQ--HGGPPLLPES 465
             +   P  +LT  + P  E  T    +  ++ L+ S       PPAI+     PP  P +
Sbjct: 1660 HTSTAPIAELT-TSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTA 1718

Query: 466  SEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL-THQEAPAQTPE 524
                            +  P        T   ++A  P T +   +S  T    P  TP 
Sbjct: 1719 PTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPS 1778

Query: 525  FPNVVVAQP 533
                   +P
Sbjct: 1779 IIRTTGLRP 1787



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 46/199 (23%), Positives = 65/199 (32%), Gaps = 24/199 (12%)

Query: 681  EPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
            +P+T   TT   P    +T   +       +     T  P+    T+T  PT     +PT
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358

Query: 741  TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTE 789
            T   +T        + P PT   T+T  +T +  TT     P P   Q+       + T 
Sbjct: 1359 TTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413

Query: 790  VTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPE 849
            VT  PT       +     + T       P   +A T T I    T        +   P 
Sbjct: 1414 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST--------VTPTPT 1465

Query: 850  QRLRQVPVPEPNTHNGTFT 868
                Q P   P T   T T
Sbjct: 1466 PTGTQTPTTTPITTTTTVT 1484


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 82.8 bits (203), Expect = 1e-15
 Identities = 177/751 (23%), Positives = 279/751 (37%), Gaps = 141/751 (18%)

Query: 118 EQPLEPEQFLASQQD----LKDKLSPQERLPVSPK-KLKKDPAQRWSLAEIIGIARQLST 172
           E+ + PE+  A  ++    L + +   E  P  P  +LK D +Q+ S     G    ++ 
Sbjct: 89  EETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRT---GYWTMMNI 145

Query: 173 PQSQK-QTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGP----SQFHLEPETQNP 227
           P  +K    Q  Y S       S P     KS E     +  G          +P T + 
Sbjct: 146 PPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSN 205

Query: 228 ETL--EDIQSSSLQQEAPAQLPQLLEEEPSS-----MQQEAPALPPESSMESLTLPNHE- 279
           E +  ++I  +S  QE     P LLE+E        + QE  A+   +S E +  P+ E 
Sbjct: 206 EEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE-IEPPSTEK 264

Query: 280 --VSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPI--QFPEEVEP 335
               +QPP  ++A         +   V+V  ++E T + E++ A  E  +  Q P   E 
Sbjct: 265 FPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEA 324

Query: 336 SATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQ---PPEHHEV 392
              +  A I+PP +     + +  +  P    ES  E        E P +   PP     
Sbjct: 325 PLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE--------EPPAEILPPPAEKSP 376

Query: 393 TVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPP 452
           +V   G      + SPS    P +VQ  + AE + E        EA A+       VEPP
Sbjct: 377 SVELLGE-----IRSPSAQKAPIEVQ-PLPAEGALE--------EAPAK-------VEPP 415

Query: 453 AIQH---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEG 509
            ++       PLLPE +       +Q  T+ ++P        +PT+ ++      TAEE 
Sbjct: 416 TVEETLADVQPLLPEEAPREEARELQLSTAMETPA-----EEAPTEFQSPLPKETTAEEA 470

Query: 510 ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKE 569
            +            E   +   +PP      +A   PL    T   E+  EV+ SP  +E
Sbjct: 471 SA------------EIQLLAATEPPADETPAEAR-SPLSEE-TSAEEAHAEVQ-SPLAEE 515

Query: 570 TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
           T  +     +  L   +   + TP +  AQ P+S   + +          E   EV    
Sbjct: 516 TTAEEASAEIQLLAAIEAPADETPAE--AQSPLSEETSAE----------EAPAEV---Q 560

Query: 630 APKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT 689
           +P    VS +   + L  P   +T     + A +Q L        ++  EV+P  A    
Sbjct: 561 SPSAKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATEASAEEAPAEVQPPPAEEAP 619

Query: 690 A---PPPGHP---EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE- 742
           A   PPP      EV  PP+++  A+        VQP   E     +   EV+P P  E 
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAE--------VQPPPAE-----EAPAEVQPPPAEEA 666

Query: 743 ETSTQPP---DLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSL------------ 787
               QPP   +    +   P  ET     L    +P  D V +   S+            
Sbjct: 667 PAEVQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLT 726

Query: 788 ---------TEVTGPPTELEPAQDSLVQSES 809
                     EV+ PP+E  P  ++LV++ S
Sbjct: 727 EEFPIGEASAEVSPPPSEQTPEDEALVENVS 757



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 85/336 (25%), Positives = 129/336 (38%), Gaps = 53/336 (15%)

Query: 92  SSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
           S+ M  P +E+       L    +A E   E  Q LA+ +   D+   + R P+S +   
Sbjct: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEI-QLLAATEPPADETPAEARSPLSEETSA 501

Query: 152 KD-------PAQRWSLAEIIGIARQL---------STPQSQKQTLQNEYSSTDTPYPSSL 195
           ++       P    + AE      QL          TP   +  L  E S+ + P     
Sbjct: 502 EEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561

Query: 196 PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL-PQLLEEEP 254
           P    V  +E P   +     +   E  +   + L   ++S+  +EAPA++ P   EE P
Sbjct: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA--EEAPAEVQPPPAEEAP 619

Query: 255 SSMQ----QEAPA--LPP---ESSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPAD 303
           + +Q    +EAPA   PP   E+  E    P  E    VQPP  ++A          PA+
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA----------PAE 669

Query: 304 VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE--------PPVS-PMEHE 354
           V+     E   E +S  A +ETPI+       S    + P E        PP    +  E
Sbjct: 670 VQPPPAEEAPAEVQSLPA-EETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEE 728

Query: 355 LSISEQQQPVQ--PSESSREVESSLTQQETPGQPPE 388
             I E    V   PSE + E E+ +    T  Q P+
Sbjct: 729 FPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 79.7 bits (195), Expect = 1e-14
 Identities = 146/639 (22%), Positives = 223/639 (34%), Gaps = 119/639 (18%)

Query: 194  SLPPELRVKSD-----EPPGPSEQVGPSQFHLEPET-QNPETLEDIQSSSLQQEAPAQLP 247
            ++PP   +K+       PP      G SQ H    T + P +L    SS+   E      
Sbjct: 1483 TIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTST 1542

Query: 248  QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVT 307
              +   P+S +   P     S+  S   P       P G        P  +  P    +T
Sbjct: 1543 TTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS------PFSSTGP----MT 1592

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPS 367
             TS  T  T  + +  +T +  P  V P +T         V+P  H +        + P+
Sbjct: 1593 ATSFKTTTTYPTPSHPQTTL--PTHVPPFSTSL-------VTPSTHTV--------ITPT 1635

Query: 368  ESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
             +     +S+    T   PP     T+   G   T    +P++++        +++  +A
Sbjct: 1636 HAQMATSASIHSMPTGTIPPP---TTLKATGSTHT----APTMTLTTSGTSQALSSLNTA 1688

Query: 428  EVGTSLV-------HQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            +  TSL        H EAT   S S  ++ P     G PP+   +S  +     Q  +SF
Sbjct: 1689 KTSTSLHSHTSSTHHAEAT---STSTTNITPNPTSTGTPPMTVTTSGTS-----QSRSSF 1740

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSH 538
             + +     + S     ++  HP+      +S+T  H     +TP             +H
Sbjct: 1741 STAKT----STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV------------AH 1784

Query: 539  LTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN-PTPGQDQ 597
             T AT   L   FT          +S T   T T            +Q  T  PTP    
Sbjct: 1785 TTSATSSRLPTPFTTHSPPTGTTPISSTGPVTATS-----------FQTTTTYPTPSHPH 1833

Query: 598  AQHPVS-PSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVS-PKHPEVTLPHPDQVQTQH 655
               P   PS +  L      +TP   T +  +     T  S    P  T+P P  ++   
Sbjct: 1834 TTLPTHVPSFSTSL------VTPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATG 1887

Query: 656  SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
            S  T   + P   G + +P S +  + ST+L        HPEVT  P+        H + 
Sbjct: 1888 STHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTNITPKHTST 1945

Query: 716  ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALE---KT 772
             T  P    +  TT  ++   P+P T    T  P  G      P + TG  TA      T
Sbjct: 1946 GTRTP----VAHTTSASSSRLPTPFT----THSPPTG----SSPFSSTGPMTATSFQTTT 1993

Query: 773  TAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYT 811
            T P P   Q         T  PT + P   SLV   ++T
Sbjct: 1994 TYPTPSHPQ---------TTLPTHVPPFSTSLVTPSTHT 2023



 Score = 64.3 bits (155), Expect = 5e-10
 Identities = 112/555 (20%), Positives = 178/555 (32%), Gaps = 103/555 (18%)

Query: 325  TPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPG 384
            T I       PS +    P  P  +P+      S +  P   S       +++T Q T G
Sbjct: 1228 TTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSK--PTASSGEPPRPTTAVTPQATSG 1285

Query: 385  QPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSG 444
             PP                     S + KP   Q T  A  S     +    ++T R + 
Sbjct: 1286 LPPT----------------ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTM 1329

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
            +     P     G  P LP+S+ +  P     +T+   P P            A+   P 
Sbjct: 1330 T----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTP------------ASTTGPT 1373

Query: 505  TAEEG--------ESSLTHQEAPAQTPEFPNVVVAQP----------------------- 533
            T + G        E++ T       TP+ P+   + P                       
Sbjct: 1374 TPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433

Query: 534  --PEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P H   T  T  P      +TP   T   ++PT  +  T       P   +    T  
Sbjct: 1434 PTPSHPETTLPTHVPPFSTSLVTPS--THTVITPTHAQMATSASNHSAPTGTIPPPTTLK 1491

Query: 592  TPGQDQAQHPVSPSVT-VQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQ 650
              G      P++P+ +         +    PT+   H+++     V+P       P+P  
Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 651  VQTQH--SHLTRATVQPLDLGFTI-------TPKSMTEVEPSTALMTTA--PPPGHPEVT 699
             +T+   +H   AT       FT        +P S T    +T+  TT   P P HP+ T
Sbjct: 1552 TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 700  LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEP 759
            LP                V P    L +T    T + P+     TS     +    IP P
Sbjct: 1612 LP--------------THVPPFSTSL-VTPSTHTVITPTHAQMATSASIHSMPTGTIPPP 1656

Query: 760  TT-----ETGHSTALEKTTAPHPDRVQSLH--RSLTEVTGPPTELEPAQDSLVQSESYTQ 812
            TT      T  +  +  TT+     + SL+  ++ T +    +    A+ +   + + T 
Sbjct: 1657 TTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITP 1716

Query: 813  NKALTAPEEQKASTS 827
            N   T       +TS
Sbjct: 1717 NPTSTGTPPMTVTTS 1731



 Score = 59.7 bits (143), Expect = 1e-08
 Identities = 127/654 (19%), Positives = 221/654 (33%), Gaps = 95/654 (14%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            S+P S    +      T T YP+   P+  + +  PP  +  V PS   +      P   
Sbjct: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI----TPTHA 1637

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN---HEVSVQPPGE 287
            +   S+S+       +P     + +     AP +   +S  S  L +    + S      
Sbjct: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697

Query: 288  DQAYYHLP-------NITVKPADV---EVTITSEPTNETESSQAQQETPIQFPE------ 331
              + +H         NIT  P       +T+T+  T+++ SS +  +T            
Sbjct: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757

Query: 332  --EVEPSATQQEAPIEPPV---SPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQP 386
              EV  ++T    P        +P+ H  S +  + P   +  S    ++      P   
Sbjct: 1758 HPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817

Query: 387  PEHHEVTVSP-PGHHQTH---HLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARL 442
                  T  P P H  T    H+ S S S+  P     I    +    ++ +H   T  +
Sbjct: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877

Query: 443  SGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH 502
                  ++     H  PP+ P +S  +     Q  +SF + +     + S     ++  H
Sbjct: 1878 PPP-TTIKATGSTHTAPPMTPTTSGTS-----QSPSSFSTAKT----STSLPYHTSSTHH 1927

Query: 503  PQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTE 560
            P+      +++T  H     +TP             +H T A+   L   FT        
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPV------------AHTTSASSSRLPTPFTTHSPPTGS 1975

Query: 561  VELSPTMKETPTQPPKKVVPQLRVYQGVTN-PTPGQDQAQHP--VSPSVTVQLLDLGLTI 617
               S T   T T            +Q  T  PTP   Q   P  V P  T  +     T+
Sbjct: 1976 SPFSSTGPMTATS-----------FQTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV 2024

Query: 618  TPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSM 677
                 T++  S +   T      P  T+P P  ++   S  T   +     G + T  S 
Sbjct: 2025 IITTHTQMATSASIHST------PTGTVPPPTTLKATGSTHTAPPMTVTTSGTSQTHSSF 2078

Query: 678  TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
            +    S++ ++++        + PPS     Q  HL+ AT       ++ T + ++   P
Sbjct: 2079 STATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT-----PVSTTNQLSSSFSP 2133

Query: 738  SPTTEET------------STQPPDLGL--AIIPEPTTETGHSTALEKTTAPHP 777
            SP+   T             T  P +G   + +  P   T  S+    + + HP
Sbjct: 2134 SPSAPSTVSSYVPSSHSSPQTSSPSVGTSSSFVSAPVHSTTLSSGSHSSLSTHP 2187


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 78.6 bits (192), Expect = 2e-14
 Identities = 160/731 (21%), Positives = 236/731 (32%), Gaps = 101/731 (13%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3784

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3785 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3828

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 3829 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3879

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3939

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3940 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3995 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4054

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 4055 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 4108

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 4109 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 4154

Query: 636  VSPKHPEVTLPHPDQVQTQHSH----LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
            ++        P P   QT  +      T  T  P   G    P + T   P   L T+ P
Sbjct: 4155 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNP 4214

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQ----PLDLELTITTKPTTEVKPSPTTEETSTQ 747
            PP   E + P + +  +  S LT++T      P  +E+T T  P+T   P+ T+   +  
Sbjct: 4215 PP---ESSTPQTSRSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269

Query: 748  PPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPP---------TELE 798
            PP       P  T   G +T    ++AP P  VQ+   S    T  P         T L 
Sbjct: 4270 PPP-STTTSPPGTPTRGTTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLR 4326

Query: 799  PAQDSLVQSESYTQNKALTAP-EEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPV 857
            P   S++       N    AP EE    T  + C    C    LSC            P 
Sbjct: 4327 PYPSSVL--ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCPSTPS 4381

Query: 858  PEPNTHNGTFT 868
            P P     T T
Sbjct: 4382 PTPTPSKSTPT 4392



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 92/372 (24%), Positives = 120/372 (32%), Gaps = 35/372 (9%)

Query: 459  PPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
            PP  P S+    P       +  +  P     PSP         P T      S T    
Sbjct: 1408 PP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 519  PAQTPEFPNVVVAQP---PEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKET---PT 572
            P  TP  P    + P   P     T  T  P     T TP   T   ++P    T   PT
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP-----TTTPSPPTTTPITPPASTTTLPPT 1520

Query: 573  QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---ST 629
              P             T P+P       P++P  +   L    T +P PTT       +T
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 630  APKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT- 688
                T  +P  P +T   P    T     T  T  P     T +P + T + P T+  T 
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTL 1635

Query: 689  ---TAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
               T P P     T PP     +  +     T  P     T TT P T    SP T  T+
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPT-----TTTPSPPITTTTTPPPTTTPSSPIT--TT 1688

Query: 746  TQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLV 805
              PP   +   P PTT    S+ +  TT P      S   +      P T   P   ++ 
Sbjct: 1689 PSPPTTTMTT-PSPTTTP--SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745

Query: 806  QSESYTQNKALT 817
                 T +  LT
Sbjct: 1746 TLPPTTTSSPLT 1757



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 111/431 (25%), Positives = 134/431 (31%), Gaps = 63/431 (14%)

Query: 387  PEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTI---AAEPSAEVGTSLVHQEATARLS 443
            P     T SPP    T     P+ +  PP    T       PS  + T+      T    
Sbjct: 1399 PSPPTTTPSPPPTSTTTL--PPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSP 1456

Query: 444  GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQ-----EA 498
                   PP      PP    S     P      T+  +P P    +P  T         
Sbjct: 1457 PISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTT--TPPPTTTPSPPTTTPITPPAST 1514

Query: 499  AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESM 558
                P T     ++ T    P  TP  P      PP  +     T  P     T T    
Sbjct: 1515 TTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPP 1574

Query: 559  TEVELSPTMKE------TPTQPPKKVVPQLRVYQGVTNP--TPGQDQAQHPVSPSVTVQL 610
            T     PT         T T PP    P        T P  T        P++P  +   
Sbjct: 1575 TTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTT 1634

Query: 611  LDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
            L    T +P PTT    +T P  T  SP  P  T P P         +T  T  P     
Sbjct: 1635 LPPTTTPSPPPTTT---TTPPPTTTPSP--PTTTTPSPP--------ITTTTTPPP---- 1677

Query: 671  TITPKS--MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTIT 728
            T TP S   T   P T  MTT      P  T  PS       S +T  T        T +
Sbjct: 1678 TTTPSSPITTTPSPPTTTMTT------PSPTTTPS-------SPITTTTTP--SSTTTPS 1722

Query: 729  TKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLT 788
              PTT   PSPT   T+  PP   +  +P PTT     T+   TT P P  +     S  
Sbjct: 1723 PPPTTMTTPSPT---TTPSPPTTTMTTLP-PTT-----TSSPLTTTPLPPSITPPTFSPF 1773

Query: 789  EVTGPPTELEP 799
              T P T   P
Sbjct: 1774 STTTPTTPCVP 1784



 Score = 72.4 bits (176), Expect = 2e-12
 Identities = 102/448 (22%), Positives = 131/448 (29%), Gaps = 65/448 (14%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
            P D  +T  S PT           T    P    PS         PP +     ++ +  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTT---LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 361  QQPV---QPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVS------ 411
              P     P  S+       T    P   P     T SPP    T    + + S      
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 412  VKPPDVQLTI--AAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEA 469
            + PP    T+     PS    T+      T     +   + PP      PP    S    
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP-- 1565

Query: 470  GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVV 529
             P          +P P     PSP         P T     ++ T    P  TP  P   
Sbjct: 1566 -PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTT 1624

Query: 530  VAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVT 589
               PP     T  T  P     T TP        SP    T T PP             T
Sbjct: 1625 PITPP-----TSTTTLPP----TTTP--------SPPPTTTTTPPP------------TT 1655

Query: 590  NPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPD 649
             P+P          P+ T     +  T TP PTT     T       +P  P  T+  P 
Sbjct: 1656 TPSP----------PTTTTPSPPITTTTTPPPTT-----TPSSPITTTPSPPTTTMTTPS 1700

Query: 650  QVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQ 709
               T  S +T  T        +  P +MT   P+    TT  PP     TLPP+      
Sbjct: 1701 PTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT----TTPSPPTTTMTTLPPTTTSSPL 1756

Query: 710  HSHLTQATVQPLDLELTITTKPTTEVKP 737
             +     ++ P       TT PTT   P
Sbjct: 1757 TTTPLPPSITPPTFSPFSTTTPTTPCVP 1784



 Score = 71.6 bits (174), Expect = 3e-12
 Identities = 151/695 (21%), Positives = 219/695 (31%), Gaps = 109/695 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3715

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3716 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3759

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 3760 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3810

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3870

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3871 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3926 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3985

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3986 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 4039

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 4040 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 4085

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 4086 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 4135

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAI 755
              VT  P+  G          T  P    +T TT  T    P+PT  +T T  P      
Sbjct: 4136 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 4183

Query: 756  IPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVT--GPPTELEPAQDSLVQSESYTQN 813
            +    T TG  T     T+  P         + E+T   PP E    Q S   S   T++
Sbjct: 4184 VTPTPTPTGTQTGPPTHTSTAP---------IAELTTSNPPPESSTPQTSRSTSSPLTES 4234

Query: 814  KALTA---PEEQKAST---STNICELCTCGDEMLS 842
              L +   P  +  ST   ST      T G   LS
Sbjct: 4235 TTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269



 Score = 71.2 bits (173), Expect = 4e-12
 Identities = 83/315 (26%), Positives = 99/315 (31%), Gaps = 59/315 (18%)

Query: 491  PSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG 550
            PSP         P T     ++ T    P  TP  P      PP                
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP--------------- 1450

Query: 551  FTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL 610
             T TP        +P    TP+ P     P        T  T        P  P+ T   
Sbjct: 1451 -TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTT--- 1506

Query: 611  LDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGF 670
                  ITP  +T    +T P  T  SP     T P P    T  S  T   + P     
Sbjct: 1507 -----PITPPAST----TTLPPTTTPSPPTTTTTTPPPT---TTPSPPTTTPITPPTSTT 1554

Query: 671  TITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK 730
            T+ P +     P+T   TT PPP     T  PS             T  P    +T TT 
Sbjct: 1555 TLPPTTTPSPPPTT---TTTPPP-----TTTPSPP----------TTTTPSPPTITTTTP 1596

Query: 731  PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETG-----HSTALEKTTAPHPDRVQSLHR 785
            P T   PSP T  T+T PP       P P T T       +T L  TT P P    +   
Sbjct: 1597 PPTTT-PSPPTTTTTTPPP----TTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP 1651

Query: 786  SLTEVTGPPTELEPA 800
              T    PPT   P+
Sbjct: 1652 PPTTTPSPPTTTTPS 1666



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2059

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2060 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2103

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2104 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2154

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2214

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2215 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2329

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2330 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2383

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2384 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 2429

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 2430 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2479

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 2480 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 2527

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 2528 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2587

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 2588 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 2639

Query: 864  NGTFT 868
              T T
Sbjct: 2640 TTTVT 2644



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2174

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2175 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2218

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2219 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2269

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2329

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2330 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2444

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2445 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2498

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2499 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 2544

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 2545 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2594

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 2595 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 2642

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 2643 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 2754

Query: 864  NGTFT 868
              T T
Sbjct: 2755 TTTVT 2759



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2289

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2290 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2333

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2334 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2384

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2444

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2445 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2613

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2614 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 2659

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 2660 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2709

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 2710 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 2757

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 2758 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2817

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 2818 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 2869

Query: 864  NGTFT 868
              T T
Sbjct: 2870 TTTVT 2874



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2404

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2405 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2448

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2449 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2499

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2559

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2560 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2674

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2675 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2728

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2729 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 2774

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 2775 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2824

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 2825 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 2872

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 2873 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2932

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 2933 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 2984

Query: 864  NGTFT 868
              T T
Sbjct: 2985 TTTVT 2989



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2519

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2520 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2563

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2564 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2614

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2674

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2675 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2843

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2844 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 2889

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 2890 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 2939

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 2940 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 2987

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 2988 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3047

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3048 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3099

Query: 864  NGTFT 868
              T T
Sbjct: 3100 TTTVT 3104



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2634

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2635 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2678

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2679 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2729

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2789

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2790 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 2958

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 2959 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3004

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3005 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3054

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3055 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3102

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3103 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3162

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3163 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3214

Query: 864  NGTFT 868
              T T
Sbjct: 3215 TTTVT 3219



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2749

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2750 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2793

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2794 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2844

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2904

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 2905 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 3073

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 3074 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3119

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3120 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3169

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3170 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3217

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3218 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3277

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3278 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3329

Query: 864  NGTFT 868
              T T
Sbjct: 3330 TTTVT 3334



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2864

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2865 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2908

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2909 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2959

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3019

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3020 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 3188

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 3189 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3234

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3235 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3284

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3285 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3332

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3333 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3392

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3444

Query: 864  NGTFT 868
              T T
Sbjct: 3445 TTTVT 3449



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2979

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2980 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3023

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 3024 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3074

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3134

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3135 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3249

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 3303

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 3304 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3349

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3350 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3399

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3400 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3447

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3448 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3507

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3508 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3559

Query: 864  NGTFT 868
              T T
Sbjct: 3560 TTTVT 3564



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3094

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3095 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3138

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 3139 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3189

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3249

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3250 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3364

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3365 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 3418

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 3419 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3464

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3465 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3514

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3515 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3562

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3563 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3622

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3623 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3674

Query: 864  NGTFT 868
              T T
Sbjct: 3675 TTTVT 3679



 Score = 68.2 bits (165), Expect = 3e-11
 Identities = 155/725 (21%), Positives = 227/725 (31%), Gaps = 112/725 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3209

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3210 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3253

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 3254 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3304

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3364

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGG--PPLLP- 463
            + + +  P     T+   P+   GT    Q  T     +   V P     G   P   P 
Sbjct: 3365 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419

Query: 464  ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---TH 515
             ++    P      T   +  PI         P+PT  +     P T     +     T 
Sbjct: 3420 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3479

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPP 575
             + P  TP      V   P  +     T  P+    T+TP        +PT  +TPT  P
Sbjct: 3480 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTP 3533

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI 635
                  +        PTP     Q P +  +T        T+TP PT   G  T P  T 
Sbjct: 3534 ITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTP 3579

Query: 636  VSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
            ++        P P   QT        T  P+    T+TP   T     T   TT P    
Sbjct: 3580 ITTTTTVTPTPTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTT 3629

Query: 696  PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLA 754
              VT  P+  G          T  P    +T TT  T    P+PT  +T +T P      
Sbjct: 3630 TTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTT 3677

Query: 755  IIPEPT---TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDS 803
            + P PT   T+T  +T +  TT     P P   Q+       + T VT  PT       +
Sbjct: 3678 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3737

Query: 804  LVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
                 + T       P   +  T+T I    T        +   P     Q P   P T 
Sbjct: 3738 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITT 3789

Query: 864  NGTFT 868
              T T
Sbjct: 3790 TTTVT 3794



 Score = 66.6 bits (161), Expect = 9e-11
 Identities = 151/714 (21%), Positives = 222/714 (31%), Gaps = 113/714 (15%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P+  P   +  +  P   +  V P+       TQ P T  
Sbjct: 1912 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 1967

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 1968 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2011

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+
Sbjct: 2012 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2062

Query: 352  EHELSISEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLD 406
                +++    P     P+ +     +++T   TP   Q P    +T +           
Sbjct: 2063 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2122

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESS 466
            + + +  P     T+   P+   GT    Q  T     +   V P     G        +
Sbjct: 2123 TQTPTTTPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTG------TQT 2171

Query: 467  EEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP 526
                P+     T   +P P   + P+ T          T        T  + P  TP   
Sbjct: 2172 PTTTPITTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITT 2225

Query: 527  NVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
               V   P  +     T  P+    T+TP        +PT  +TPT  P      +    
Sbjct: 2226 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTPITTTTTV---- 2275

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLP 646
                PTP     Q P +  +T        T+TP PT   G  T P  T ++        P
Sbjct: 2276 ---TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTPITTTTTVTPTP 2325

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
             P   QT        T  P+    T+TP   T     T   TT P      VT  P+  G
Sbjct: 2326 TPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTG 2375

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLAIIPEPT---TE 762
                      T  P    +T TT  T    P+PT  +T +T P      + P PT   T+
Sbjct: 2376 ----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2423

Query: 763  TGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDSLVQSESYTQNK 814
            T  +T +  TT     P P   Q+       + T VT  PT       +     + T   
Sbjct: 2424 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2483

Query: 815  ALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
                P   +  T+T I    T        +   P     Q P   P T   T T
Sbjct: 2484 PTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2529



 Score = 66.2 bits (160), Expect = 1e-10
 Identities = 176/836 (21%), Positives = 242/836 (28%), Gaps = 152/836 (18%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
            PS  +  P+PP  ST  L P              P     S         P    P  P 
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458

Query: 149  KLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPG 208
                 P    + +         +TP     T     ++T TP P++ P         PP 
Sbjct: 1459 STTTTPPPTTTPSP------PTTTPSPPTTTPSPPTTTTTTPPPTTTP--------SPPT 1504

Query: 209  PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             +    P+     P T  P       +++     P   P      P +       LPP +
Sbjct: 1505 TTPITPPASTTTLPPTTTPSP----PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTT 1560

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQ 328
            +      P    +  PP    +    P  T  P+   +T T+ P   T S      T   
Sbjct: 1561 TPSP---PPTTTTTPPPTTTPS----PPTTTTPSPPTITTTTPPPTTTPSPPTTTTT--- 1610

Query: 329  FPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPE 388
                  P  T    P   P++P               P+ +     ++L    TP  PP 
Sbjct: 1611 ----TPPPTTTPSPPTTTPITP---------------PTST-----TTLPPTTTPSPPP- 1645

Query: 389  HHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGND 448
                T +PP          P+ +  PP         PS  + T+      T   S     
Sbjct: 1646 --TTTTTPP----------PTTTPSPP-----TTTTPSPPITTTTTPPPTTTPSSPITTT 1688

Query: 449  VEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEE 508
              PP      P      S           T+  SP P     PSPT        P T   
Sbjct: 1689 PSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPT----TTPSPPTTTM 1744

Query: 509  GESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQP-----------LD--------- 548
                 T   +P  T   P  +   PP  S  +  T              LD         
Sbjct: 1745 TTLPPTTTSSPLTTTPLPPSIT--PPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKP 1802

Query: 549  ------LGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPV 602
                  +G    P     +    TM   P  P  ++   +     V      +DQ    V
Sbjct: 1803 GGDTELIGDVCGPGWAANISCRATM--YPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGV 1860

Query: 603  SP-------SVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQH 655
             P        + VQ  +     T   TT   + T P  T ++        P P   QT  
Sbjct: 1861 IPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQT-- 1918

Query: 656  SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSH--- 712
                  T  P+    T+TP   T     T   TT P      VT  P+  G    +    
Sbjct: 1919 -----PTTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1970

Query: 713  LTQATVQPLDLEL---TITTKP---TTEVKPSPT---TEETSTQPPDLGLAIIPEPT--- 760
             T  TV P        T TT P   TT V P+PT   T+  +T P      + P PT   
Sbjct: 1971 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2030

Query: 761  TETGHSTALEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDSLVQSESYTQ 812
            T+T  +T +  TT     P P   Q+       + T VT  PT       +     + T 
Sbjct: 2031 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2090

Query: 813  NKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
                  P   +  T+T I    T        +   P     Q P   P T   T T
Sbjct: 2091 VTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2138



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 81/286 (28%), Positives = 96/286 (33%), Gaps = 41/286 (14%)

Query: 553  ITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLD 612
            IT  S      SP    T T PP             T P+P       P  P  T     
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPP------------TTTPSPPTTTTTTP--PPTTTPSPP 1441

Query: 613  LGLTITPEPTTE----VGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
            +  T TP PTT     +  +T P  T  +   P  T P P          T  T  P   
Sbjct: 1442 ITTTTTPPPTTTPSPPISTTTTPPPT--TTPSPPTTTPSPPTTTPSPPTTTTTTPPPTT- 1498

Query: 669  GFTITPKSMTEVEP----STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
              T +P + T + P    +T   TT P P     T PP        S  T   + P    
Sbjct: 1499 --TPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPP---TTTPSPPTTTPITP--PT 1551

Query: 725  LTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLH 784
             T T  PTT   P PTT  T+T PP       P P T T  S     TT P P    S  
Sbjct: 1552 STTTLPPTTTPSPPPTT--TTTPPP----TTTPSPPTTTTPSPPTITTTTPPPTTTPS-P 1604

Query: 785  RSLTEVTGPPTEL--EPAQDSLVQSESYTQNKALTAPEEQKASTST 828
             + T  T PPT     P    +    S T     T P     +T+T
Sbjct: 1605 PTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTT 1650



 Score = 63.5 bits (153), Expect = 8e-10
 Identities = 131/588 (22%), Positives = 187/588 (31%), Gaps = 87/588 (14%)

Query: 298  TVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSI 357
            T  P     T+T  PT     +Q    TPI     V P+ T       P  +P+    ++
Sbjct: 1897 TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTV 1953

Query: 358  SEQQQPV---QPSESSREVESSLTQQETPG--QPPEHHEVTVSPPGHHQTHHLDSPSVSV 412
            +    P     P+ +     +++T   TP   Q P    +T +           + + + 
Sbjct: 1954 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2013

Query: 413  KPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPL 472
             P     T+   P+   GT    Q  T     +   V P     G        +    P+
Sbjct: 2014 TPITTTTTVTPTPTP-TGT----QTPTTTPITTTTTVTPTPTPTG------TQTPTTTPI 2062

Query: 473  AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ 532
                 T   +P P   + P+ T          T        T  + P  TP      V  
Sbjct: 2063 TTTT-TVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITTTTTVTP 2116

Query: 533  PPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPT 592
             P  +     T  P+    T+TP        +PT  +TPT  P      +        PT
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTPITTTTTV-------TPT 2163

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQ 652
            P     Q P +  +T        T+TP PT   G  T P  T ++        P P   Q
Sbjct: 2164 PTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTPITTTTTVTPTPTPTGTQ 2216

Query: 653  TQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSH 712
            T        T  P+    T+TP   T     T   TT P      VT  P+  G      
Sbjct: 2217 TP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTG------ 2260

Query: 713  LTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLAIIPEPT---TETGHSTA 768
                T  P    +T TT  T    P+PT  +T +T P      + P PT   T+T  +T 
Sbjct: 2261 ----TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314

Query: 769  LEKTT----APHPDRVQSLH----RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPE 820
            +  TT     P P   Q+       + T VT  PT       +     + T       P 
Sbjct: 2315 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2374

Query: 821  EQKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
              +  T+T I    T        +   P     Q P   P T   T T
Sbjct: 2375 GTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2414



 Score = 53.9 bits (128), Expect = 6e-07
 Identities = 86/341 (25%), Positives = 114/341 (33%), Gaps = 62/341 (18%)

Query: 540  TQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQ 599
            T  T  P+    T+TP        +PT  +TPT  P      +        PTP     Q
Sbjct: 1894 TPPTTTPITTTTTVTPTP------TPTGTQTPTTTPITTTTTV-------TPTPTPTGTQ 1940

Query: 600  HPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLT 659
             P +  +T        T+TP PT   G  T P  T ++        P P   QT      
Sbjct: 1941 TPTTTPITTTT-----TVTPTPTP-TGTQT-PTTTPITTTTTVTPTPTPTGTQTP----- 1988

Query: 660  RATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
              T  P+    T+TP   T     T   TT P      VT  P+  G          T  
Sbjct: 1989 --TTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTG----------TQT 2033

Query: 720  PLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLAIIPEPT---TETGHSTALEKTT-- 773
            P    +T TT  T    P+PT  +T +T P      + P PT   T+T  +T +  TT  
Sbjct: 2034 PTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2091

Query: 774  --APHPDRVQSLH----RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTS 827
               P P   Q+       + T VT  PT       +     + T       P   +  T+
Sbjct: 2092 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2151

Query: 828  TNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
            T I    T        +   P     Q P   P T   T T
Sbjct: 2152 TPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2184



 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 48/177 (27%), Positives = 57/177 (32%), Gaps = 20/177 (11%)

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA 690
            P    ++   P  T P P    T     T     P     T TP   T   P     TT 
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTT--TTTPPPTTTPSPPITTTTTP 1448

Query: 691  PPPGHPE------VTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTT--- 741
            PP   P        T PP+       +  +  T  P     T TT P T     PTT   
Sbjct: 1449 PPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508

Query: 742  ---EETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPT 795
                 T+T PP       P P T T  +T    TT P P     +    +  T PPT
Sbjct: 1509 TPPASTTTLPP----TTTPSPPTTT--TTTPPPTTTPSPPTTTPITPPTSTTTLPPT 1559


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 76.3 bits (186), Expect = 1e-13
 Identities = 159/757 (21%), Positives = 270/757 (35%), Gaps = 120/757 (15%)

Query: 206  PPGPSEQVGPSQFHLEPETQN--PETLEDI--QSSSLQQEAPAQLPQLLEEEPSSMQQE- 260
            P   +E+VGP +  LE ET+   PE   D+  +    + +   +  QLL  +    + + 
Sbjct: 817  PKETAERVGPERGPLERETEKLLPERQTDVTGEEELTKGKQDREQKQLLARDTQRQESDK 876

Query: 261  -APALPPESSMESLTLPNH------EVSVQPPG------EDQAYYHLPNITVKPADVEVT 307
               +  PE   ESL +         E  VQ         E +    + N    PA++E  
Sbjct: 877  NGESASPERDRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVANRECDPAELEEK 936

Query: 308  ITS------------EPTNETESSQAQQETP--------IQFPEEVEPSATQQEAPIEPP 347
            +              E  ++ +  QA   TP        +  P      +  Q      P
Sbjct: 937  VPKVILERDTQRGEPEGGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSP 996

Query: 348  VSPMEHELSISEQQQPVQPSESSREVES----SLTQQETPGQ--PPEHHEVTVSPP---- 397
            VSP  H+  +   + P  P+E +  + +    S   QE+P    PP   E    P     
Sbjct: 997  VSPRRHQKGLLNCKMP--PAEKASRIRAAEKVSRGDQESPDACLPPTVPEAPAPPQKPLN 1054

Query: 398  GHHQTHHLDSPSVSVKPPDVQLTIAAE--------PSAEVGTSL--------VHQEATAR 441
               Q H    P +S   P ++ T+           P A + + L        +    ++R
Sbjct: 1055 SQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSR 1114

Query: 442  LS---GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEA 498
            ++    +    EP        P+ P+ + +A      + +S ++PEP+    P   Q   
Sbjct: 1115 MTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNR-SSVKTPEPVVPTAPE-LQPST 1172

Query: 499  AAEHPQTAEEGESSLTH---QEAPAQTPEF---------PNVVVAQPPEHSHLTQATVQP 546
            + + P T+E   S +T      +  +TPE          P+    +P      +QAT   
Sbjct: 1173 STDQPVTSEP-TSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATRGR 1231

Query: 547  LDLGFTITPESM--TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP 604
             +     TPE +  T  EL P+   T T  P    P  +  +G  N +    +   PV P
Sbjct: 1232 KNRSSVKTPEPVVPTAPELQPS---TSTDQPVTSEPTYQATRGRKNRS--SVKTPEPVVP 1286

Query: 605  SVTV--QLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSH----- 657
            +             +TP+PT+    +T  +  + S K PE  +P   ++Q   S      
Sbjct: 1287 TAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVT 1343

Query: 658  ---LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
                +R T    ++     P+S   + P     T+   P  PE T   +   + + S  T
Sbjct: 1344 PKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKT 1403

Query: 715  QATVQPLDLELTITTKPTTEVKPSPTTEET-------STQPPDLGLAIIPE--PTTETGH 765
              T+ P   +L  +T     V P PT++ T       S + P+  +   PE  P+T T  
Sbjct: 1404 PETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAPELQPSTSTDQ 1463

Query: 766  STALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKAS 825
                E T+     R        + V  P T +  A +  +Q+ + T     + P  +   
Sbjct: 1464 PVTPEPTSQATRGRTDR-----SSVKTPETVVPTAPE--LQASASTDQPVTSEPTSRTTR 1516

Query: 826  TSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNT 862
               N   + T    + +  +L P     Q   PEP +
Sbjct: 1517 GRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTS 1553



 Score = 74.7 bits (182), Expect = 3e-13
 Identities = 178/827 (21%), Positives = 283/827 (34%), Gaps = 97/827 (11%)

Query: 46   PLQLTSNPLGPPESWSSHSS-HFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            P  +   P  P +  +S S  H       +P LP+            S E P  P  S  
Sbjct: 1039 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSS-- 1096

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
             L PF         +      F A+    +   S     PV+PK   +    R + + + 
Sbjct: 1097 ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV- 1155

Query: 165  GIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRV----KSDEPPGPSEQVGPSQFHL 220
                   TP+    T      ST T  P +  P  +V    KS       E V P+   L
Sbjct: 1156 ------KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALEL 1209

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
            +P T    T   + S    Q    +  +   + P  +   AP L P +S +         
Sbjct: 1210 QPSTS---TDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 281  SVQPPGEDQAYYHLPNITVKPA-------DVEVTITSEPTNETESSQAQQETPIQFPEEV 333
                  ++++    P   V  A         +  +T +PT+ T  S+    + ++ PE V
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSS-VKTPETV 1325

Query: 334  EPSA------TQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPP 387
             P+A      T  + P+ P   P             V+  ES+  +   L    +  QP 
Sbjct: 1326 VPTAPELQISTSTDQPVTP--KPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPV 1383

Query: 388  EHHEVTVSPPGHHQTHHLDSPS--VSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGS 445
                 + +  G        +P   V   P     T   +P     TS   +  T R S  
Sbjct: 1384 TPEPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVK 1443

Query: 446  GNDVEPPAIQHGGP------PLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
              +   P      P      P+ PE + +A        +S ++PE +    P   Q  A+
Sbjct: 1444 TPETVVPTAPELQPSTSTDQPVTPEPTSQA-TRGRTDRSSVKTPETVVPTAPE-LQASAS 1501

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMT 559
             + P T+E   S  T       + + P  VV   PE    T +T QP      +TPE  +
Sbjct: 1502 TDQPVTSEP-TSRTTRGRKNRSSVKTPETVVPAAPELQPST-STDQP------VTPEPTS 1553

Query: 560  EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTI-T 618
                  T + +  + P+ +VP     Q    P+  ++Q   P   S   +      ++ T
Sbjct: 1554 RATRGRTNRSS-VKTPESIVPIAPELQ----PSTSRNQLVTPEPTSRATRCRTNRSSVKT 1608

Query: 619  PEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPL--DLG-FT---- 671
            PEP         P  +   P  P++T     +   + S  T   V+P   DL  FT    
Sbjct: 1609 PEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPVEPAASDLEPFTPTDQ 1668

Query: 672  -ITPKSMTEVEPSTALMTTA----PPPGHPEVTLPPSDKGQAQHSHLTQ--------ATV 718
             +TP+++ +   S  L ++     P P  PE   P +         +TQ        A  
Sbjct: 1669 SVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAG 1728

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDL-----GLAIIPEPTT----ETG-HSTA 768
             P  L   I  KP +     P ++ +  Q          L  IPEP +    ET  H++ 
Sbjct: 1729 NPGSLAAPIDHKPCS-APLEPKSQASRNQRWGAVRAAESLTAIPEPASPQLLETPIHASQ 1787

Query: 769  LEK---------TTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQ 806
            ++K         T    P   QS  RSL  +  PP + +P +  + Q
Sbjct: 1788 IQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEVSQ 1834



 Score = 35.4 bits (80), Expect = 0.23
 Identities = 86/460 (18%), Positives = 164/460 (35%), Gaps = 89/460 (19%)

Query: 46   PLQLTSNPLGPPESWSSHSSHFPRESPHAP--TLPADPWDFDHLGPSASSEMPAPPQEST 103
            P   T  P+ P  +  +      R S   P   +P  P     L  SAS++ P   + ++
Sbjct: 1457 PSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAP----ELQASASTDQPVTSEPTS 1512

Query: 104  ---------------ENLVPFLDTWD--SAGEQPLEPEQFLASQQDLKDKLS---PQERL 143
                           E +VP        ++ +QP+ PE    + +   ++ S   P+  +
Sbjct: 1513 RTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIV 1572

Query: 144  PVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSS-----LPPE 198
            P++P+        +    E    A +  T +S  +T +    +   P+P++     + P+
Sbjct: 1573 PIAPELQPSTSRNQLVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPK 1632

Query: 199  LRVK---------SDEPPGPSEQVGPSQFHLEPETQNPETL------EDIQSSSLQQEAP 243
            L  +         S + P P E   P+   LEP T   +++      +  QS +L+    
Sbjct: 1633 LTSRATRRKTNRSSVKTPKPVE---PAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTV 1689

Query: 244  AQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLP-NITVKP- 301
              +P     E  S       + PE   +   +     +  P        H P +  ++P 
Sbjct: 1690 RAMPVPTTPEFQSPVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPK 1749

Query: 302  -------------ADVEVTITSEPTNETESSQAQQETPIQFPE--EVEPSATQQEAPIEP 346
                         A   +T   EP     +S    ETPI   +  +VEP+   +  P   
Sbjct: 1750 SQASRNQRWGAVRAAESLTAIPEP-----ASPQLLETPIHASQIQKVEPAGRSRFTPELQ 1804

Query: 347  PVSPMEHELSIS------EQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHH 400
            P +    + S++       Q+QP +   S + V     +++T  +P +  +V    PG  
Sbjct: 1805 PKASQSRKRSLATMDSPPHQKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPGKR 1864

Query: 401  QTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATA 440
            +    +     +            PS  +  + ++QE+TA
Sbjct: 1865 KRDQAEEEPNRI------------PSRSLRRTKLNQESTA 1892


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 116/509 (22%), Positives = 193/509 (37%), Gaps = 60/509 (11%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSS 194
            +K S     P  PK+    P ++ +      I+ +  T  S+K  + +E  +  +  P+ 
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPAL----------PPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPAD 303
            P S+  E P +           P  S E  T+P  + ++  P E       P     P +
Sbjct: 689  P-SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI--PTEKSTI--SPEKPTTPTE 743

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQP 363
                 T +PT   E      E P   PE++     +   P E P  P E + +IS ++  
Sbjct: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE-KPTISTEEPT 802

Query: 364  VQPSESSREVESSLTQQETPGQPPEH-----HEVTVSPPGHHQTHHLDSPSVSVKPPDVQ 418
                E++   E      E P  P E       E T+S      T  ++ P++S + P   
Sbjct: 803  TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST--EKLTIPMEKPTISTEKP--- 857

Query: 419  LTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
             TI  E       ++  ++ T          E P I       + E++     L +  E 
Sbjct: 858  -TIPTEK-----PTISPEKLTIPTEKLTIPTEKPTIP------IEETTISTEKLTIPTEK 905

Query: 479  SFQSPE--PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEH 536
               SPE   I+ E P+   ++      +T    E      E P  +PE   +   +P   
Sbjct: 906  PTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP--- 962

Query: 537  SHLTQATVQPLDLGFTITPESMTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
               T +T +P     TI  E +T     PT+  E PT P +K+   LR        T   
Sbjct: 963  ---TISTEKP-----TIPTEKLTIPTEKPTIPTEKPTIPTEKLT-ALRPPHPSPTATGLA 1013

Query: 596  DQAQHPVSPSVTVQLLDLGLTITPEPTTE 624
                 P +PS  +  + LG T T   +TE
Sbjct: 1014 ALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 119/500 (23%), Positives = 179/500 (35%), Gaps = 68/500 (13%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAA 423
              PSE         T    P + P       + P    T   + P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESMTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE +T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSP-KHPEV-----TLP------HP 648
               PS+ ++   L    T E TT V  +T     +  P + P +     T+P       P
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP 868

Query: 649  DQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL 700
            +++      LT  T +P        +       P     + P    ++T  P    E   
Sbjct: 869  EKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928

Query: 701  PPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAIIP 757
             P+++       LT  T +P     +LTI T KPT   +      E  T P +       
Sbjct: 929  IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTE 988

Query: 758  EPTTETGHSTALEKTTAPHP 777
            +PT  T   TAL     PHP
Sbjct: 989  KPTIPTEKLTALR---PPHP 1005



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 92/409 (22%), Positives = 156/409 (38%), Gaps = 56/409 (13%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPE--SWSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P E  +  S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQESTENLV--PFLDTWDSA--GEQPLEP--------EQFLA 128
                   P+  +E P  P E T   +  P + T   +   E+P  P        E+ + 
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 129 SQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGIARQLSTPQSQKQTLQNEYSST 187
           S +  K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T
Sbjct: 706 STE--KPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 188 DTPYPSSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
            T  P+  P +L + +++P  P+E+       P+    EP T   ET    +  S+  E 
Sbjct: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 243 PAQLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHL 294
           P  LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++     
Sbjct: 822 PT-LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPT 875

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPME-- 352
             +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E  
Sbjct: 876 EKLTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934

Query: 353 ----HELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP 397
                +L+I  ++  + P + +   E      E P  P E   +    P
Sbjct: 935 TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKP 983



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESMTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHSTAP-KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEQKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 79/341 (23%), Positives = 119/341 (34%), Gaps = 48/341 (14%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFT-ITPESMTEVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F  I   +   V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQA--QHPV----SPSVTVQLLDLGLTITPEPTTEVGHSTAP- 631
           +P+L     V++  P +     ++P      P+V+++   +    T +PT      T P 
Sbjct: 539 LPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSV---TTEKPTVPKEKPTIPT 595

Query: 632 --------KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPS 683
                   K TI S K P +    P     + + LT     P +     + K     E  
Sbjct: 596 EKPTISTEKPTIPSEK-PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKP 654

Query: 684 TALMTTAPPPGHPEVT-----LPPSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEV 735
           T        P     T     + P++K        +  T +P + +E TI  T KPT   
Sbjct: 655 TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 736 KPSPTTEETSTQPPDLGLAIIPEPTTETGHST--------ALEKTTAPHPDRVQSLHRSL 787
           +      E  T P +       +PTT T   T        + EK T P  ++       L
Sbjct: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKL 773

Query: 788 TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEQKAST 826
           T  T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 774 TIPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


>gi|27881494 zonadhesin isoform 6 [Homo sapiens]
          Length = 2721

 Score = 75.5 bits (184), Expect = 2e-13
 Identities = 116/509 (22%), Positives = 193/509 (37%), Gaps = 60/509 (11%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSS 194
            +K S     P  PK+    P ++ +      I+ +  T  S+K  + +E  +  +  P+ 
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPAL----------PPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPAD 303
            P S+  E P +           P  S E  T+P  + ++  P E       P     P +
Sbjct: 689  P-SIPTEKPTISMEETIISTEKPTISPEKPTIPTEKPTI--PTEKSTI--SPEKPTTPTE 743

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQP 363
                 T +PT   E      E P   PE++     +   P E P  P E + +IS ++  
Sbjct: 744  KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKPTIPTE-KPTISTEEPT 802

Query: 364  VQPSESSREVESSLTQQETPGQPPEH-----HEVTVSPPGHHQTHHLDSPSVSVKPPDVQ 418
                E++   E      E P  P E       E T+S      T  ++ P++S + P   
Sbjct: 803  TPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST--EKLTIPMEKPTISTEKP--- 857

Query: 419  LTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
             TI  E       ++  ++ T          E P I       + E++     L +  E 
Sbjct: 858  -TIPTEK-----PTISPEKLTIPTEKLTIPTEKPTIP------IEETTISTEKLTIPTEK 905

Query: 479  SFQSPE--PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEH 536
               SPE   I+ E P+   ++      +T    E      E P  +PE   +   +P   
Sbjct: 906  PTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKP--- 962

Query: 537  SHLTQATVQPLDLGFTITPESMTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
               T +T +P     TI  E +T     PT+  E PT P +K+   LR        T   
Sbjct: 963  ---TISTEKP-----TIPTEKLTIPTEKPTIPTEKPTIPTEKLT-ALRPPHPSPTATGLA 1013

Query: 596  DQAQHPVSPSVTVQLLDLGLTITPEPTTE 624
                 P +PS  +  + LG T T   +TE
Sbjct: 1014 ALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 68.9 bits (167), Expect = 2e-11
 Identities = 119/500 (23%), Positives = 179/500 (35%), Gaps = 68/500 (13%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAA 423
              PSE         T    P + P       + P    T   + P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESMTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE +T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSP-KHPEV-----TLP------HP 648
               PS+ ++   L    T E TT V  +T     +  P + P +     T+P       P
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP 868

Query: 649  DQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL 700
            +++      LT  T +P        +       P     + P    ++T  P    E   
Sbjct: 869  EKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPT 928

Query: 701  PPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAIIP 757
             P+++       LT  T +P     +LTI T KPT   +      E  T P +       
Sbjct: 929  IPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTE 988

Query: 758  EPTTETGHSTALEKTTAPHP 777
            +PT  T   TAL     PHP
Sbjct: 989  KPTIPTEKLTALR---PPHP 1005



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 92/409 (22%), Positives = 156/409 (38%), Gaps = 56/409 (13%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPE--SWSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P E  +  S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQESTENLV--PFLDTWDSA--GEQPLEP--------EQFLA 128
                   P+  +E P  P E T   +  P + T   +   E+P  P        E+ + 
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 129 SQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGIARQLSTPQSQKQTLQNEYSST 187
           S +  K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T
Sbjct: 706 STE--KPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 188 DTPYPSSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
            T  P+  P +L + +++P  P+E+       P+    EP T   ET    +  S+  E 
Sbjct: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 243 PAQLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHL 294
           P  LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++     
Sbjct: 822 PT-LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPT 875

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPME-- 352
             +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E  
Sbjct: 876 EKLTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEET 934

Query: 353 ----HELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPP 397
                +L+I  ++  + P + +   E      E P  P E   +    P
Sbjct: 935 TISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKP 983



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESMTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHSTAP-KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEQKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 30.8 bits (68), Expect = 5.7
 Identities = 79/341 (23%), Positives = 119/341 (34%), Gaps = 48/341 (14%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFT-ITPESMTEVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F  I   +   V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQA--QHPV----SPSVTVQLLDLGLTITPEPTTEVGHSTAP- 631
           +P+L     V++  P +     ++P      P+V+++   +    T +PT      T P 
Sbjct: 539 LPELPPVSPVSSTGPSETTGLTENPTISTKKPTVSIEKPSV---TTEKPTVPKEKPTIPT 595

Query: 632 --------KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPS 683
                   K TI S K P +    P     + + LT     P +     + K     E  
Sbjct: 596 EKPTISTEKPTIPSEK-PNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKP 654

Query: 684 TALMTTAPPPGHPEVT-----LPPSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEV 735
           T        P     T     + P++K        +  T +P + +E TI  T KPT   
Sbjct: 655 TVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISP 714

Query: 736 KPSPTTEETSTQPPDLGLAIIPEPTTETGHST--------ALEKTTAPHPDRVQSLHRSL 787
           +      E  T P +       +PTT T   T        + EK T P  ++       L
Sbjct: 715 EKPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKL 773

Query: 788 TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEQKAST 826
           T  T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 774 TIPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 73.9 bits (180), Expect = 6e-13
 Identities = 151/643 (23%), Positives = 205/643 (31%), Gaps = 76/643 (11%)

Query: 192  PSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
            PS L   +  ++  PP      GP      P       +  +++S L + + +   Q  +
Sbjct: 794  PSPLGVSVSPQTKRPPTKKGSAGPDT----PIGNLSSPVSPVEASFLPENSLSF--QGSK 847

Query: 252  EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSE 311
            + P++     P  P  +   S   P     V  P ++      P++   P   E   T  
Sbjct: 848  DSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETP---TPSVVNLPFPKEGPATPA 904

Query: 312  PTN----ETESSQAQQETPIQFPEEVEPSATQQEAPIEP---PVSPMEHELSISEQQQPV 364
            P         SS  ++      P+ +  S + + AP  P   P SP     + S +  P 
Sbjct: 905  PKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964

Query: 365  QPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAE 424
             P+ +    +         G P        SP G   T    SP  +  PP      A  
Sbjct: 965  PPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT---PSPKGAPTPP------AVT 1015

Query: 425  PSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P +  G+      AT    G+     PPA      P  P+ S  A PL     T+  +  
Sbjct: 1016 PPSPKGSPA----ATPFPKGAST---PPA----ATPPSPKGSPAATPLPKGAPTTPAATL 1064

Query: 485  PINNENPS-------PTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP-EH 536
            P     P+       PT   A    P+      S       PA TP  P   +A PP + 
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKG 1124

Query: 537  SHLTQATVQPLDLGFTITP----ESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPT 592
            +  T A   P   G   TP       T     P+ K     PP K  P        T P+
Sbjct: 1125 APTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAP---TTPAATPPS 1181

Query: 593  PGQDQAQ-----HPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPH 647
            P    A       P +P+ T      GL  TP P    G  T P  T  SPK    T P 
Sbjct: 1182 PKGGLATPSPKGAPTTPAATPPSPKGGLA-TPSPK---GAPTTPAATPPSPKGGLAT-PS 1236

Query: 648  PDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL-------MTTAPPPG--HPEV 698
            P    T     T A   P   G   TP       P  A        + T P  G  +P V
Sbjct: 1237 PKGAPT-----TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAV 1291

Query: 699  TLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPE 758
              PPS KG    S    A   P     +    P T       T    T P   G   +P 
Sbjct: 1292 VTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351

Query: 759  PT-TETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPA 800
             T +  G  T       P P      H+    +T P  +  PA
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA 1394



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 192/821 (23%), Positives = 262/821 (31%), Gaps = 112/821 (13%)

Query: 56   PPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDS 115
            P  S +S S    R +P    +PA P       P A++  P  P+       P       
Sbjct: 909  PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAAT--PPSPKGGPATPSPKWAPTPP 966

Query: 116  AGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQS 175
            A   P  P+   A+    K   +P    P SPK     P+ + +            TP S
Sbjct: 967  AATPP-SPKGGPATPSP-KGAPTPPAATPPSPKGGPATPSPKGAPTP------PAVTPPS 1018

Query: 176  QKQTLQNEYSSTDTPYP--SSLPPELRVKSDEPPG-PSEQVGPSQFHLEPETQNPETLED 232
             K       S   TP+P  +S PP     S  P G P+    P      P    P     
Sbjct: 1019 PKG------SPAATPFPKGASTPPAATPPS--PKGSPAATPLPKGAPTTPAATLPSPKGG 1070

Query: 233  IQSSSLQ--QEAPAQLPQLLEEEPSSMQQEAPALPPESSMES----LTLPNHEVSVQPPG 286
              + SL+     PA  P   +  P++   +   +PP ++  S    L  P H+ +   P 
Sbjct: 1071 PATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
                       T  P     T  + P     S +    TP        P+AT        
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPAATPP----SPKGGLATPPPKGAPTTPAAT-------- 1178

Query: 347  PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQP---------PEHHEVTVSPP 397
            P SP     + S +  P  P+ +    +  L      G P         P+    T SP 
Sbjct: 1179 PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPK 1238

Query: 398  GHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGND--VEPPAIQ 455
            G   T     PS    P       A  P A    SL    AT    G+ N   V PP+ +
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPK 1298

Query: 456  HGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTH 515
             GGP   P       P A           P     P+P     A   P  + +G  +L  
Sbjct: 1299 -GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPP----AVTPP--SPKGTPTL-- 1349

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQP- 574
               PA TP           +      A       G  +TP S       P+ K  PT P 
Sbjct: 1350 ---PATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 575  -----PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPE--PTT--EV 625
                 PKK        +G   P+ G D     V+P   V L     T  P+  P T    
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKG-DLTPPAVTP---VSLKKAPATSAPKGGPATPSSK 1462

Query: 626  GHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA 685
            G  T P  T  SPK P    P P QV T  S   +A   P  +G    P     V PS+ 
Sbjct: 1463 GDPTLPAVTPPSPKEP----PAPKQVATSSSP-KKAPATPAPMGAPTLPA----VIPSSP 1513

Query: 686  LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL----ELTITTKPTTEVKPSP-- 739
                A P    +   P +       S  T AT+ P +      +T+ +   T   P+P  
Sbjct: 1514 KEVPATPSSRRDPIAPTA----TLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKE 1569

Query: 740  -----TTEETSTQP----------PDLGLAIIPEPTTETGHSTALEK--TTAPHPDRVQS 782
                 +++E S+ P          P     +IP   T      A      T P P++  +
Sbjct: 1570 APATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPA 1629

Query: 783  LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQK 823
                    T PP      +DS     S T     T P+  K
Sbjct: 1630 TPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASK 1670



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 130/623 (20%), Positives = 217/623 (34%), Gaps = 97/623 (15%)

Query: 56   PPESWSSHSSHFPRESPHAPTLPADPWDFDHLGPS--ASSEMPAPPQESTENLVPFLDTW 113
            PP+   +  +  P      PTLPA        GP+  +S E P PP  +  +        
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATT-PSSKGGPTTPSSKEGPTPPAATPSHK------- 1379

Query: 114  DSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII--GIARQLS 171
                  P  P++  A      D  SP   +P+SPKK    P  R   A      +     
Sbjct: 1380 GGPAMTPPSPKRGPAIPSPKGDPTSPAV-IPLSPKKAPATPVTREGAATPSKGDLTPPAV 1438

Query: 172  TPQSQKQTLQNEYSSTDTPYPSS-----LPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
            TP S K+             PSS     LP        EPP P +    S     P T  
Sbjct: 1439 TPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
            P     +         PA +P   +E P++       + P +++ S   P          
Sbjct: 1499 PMGAPTL---------PAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP---------- 1539

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
                      +  K A +   +T     +T +        I  P+E   + + +EA   P
Sbjct: 1540 --------ATLAPKEALIPPAMTVPSPKKTPA--------IPTPKEAPATPSSKEASSPP 1583

Query: 347  PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHL- 405
             V+P  ++ + S ++  + P+ +S   + + T        PE    T +P G   +  + 
Sbjct: 1584 AVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVT 1643

Query: 406  -----DSP----SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQH 456
                 DSP    SV+ K        +    A+ G + + +   A    S   +  P  + 
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRK- 1702

Query: 457  GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPS---PTQQEAA--AEHPQTAEEGES 511
               P   +SS  + P+         S  P++   P+   P Q++++  A+    +   + 
Sbjct: 1703 --GPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKG 1760

Query: 512  SLTHQEAPAQTPEFPNVV--VAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKE 569
             L   E+ A TP        V   PE + ++ A   P+ L    +P              
Sbjct: 1761 PLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSP-------------- 1806

Query: 570  TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
             PT PPK+    L    G+   +P +     P++P+   +LL L   I PEP +      
Sbjct: 1807 VPTLPPKQQF--LPSSPGLVLESPSK-----PLAPADEDELLPL---IPPEPISGGVPFQ 1856

Query: 630  APKRTIVSPKHPEVTLPHPDQVQ 652
            +    + +PK   + +P P   Q
Sbjct: 1857 SVLVNMPTPKSAGIPVPTPSAKQ 1879



 Score = 50.1 bits (118), Expect = 9e-06
 Identities = 115/545 (21%), Positives = 183/545 (33%), Gaps = 79/545 (14%)

Query: 312 PTNETESSQAQQET---PIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQ----PV 364
           P  E E  Q Q ET   P+     V  +  Q    + PP SP   +  +S   Q    P 
Sbjct: 10  PATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPS 69

Query: 365 QPSESSREVESSLTQQE--------TPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPD 416
             + +S  +E    Q          T  + P      + PP       +   ++++  P 
Sbjct: 70  PSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPP-------ISPAALALASPM 122

Query: 417 VQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
           +  T+   PS+    +LV   A A  S   +   PP +    P +    S     L+   
Sbjct: 123 IAPTLKGTPSSSAPLALV---ALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPI 179

Query: 477 ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEH 536
             S    EP  N N  P++                       P  TP  P  +V+  P H
Sbjct: 180 APS----EPKTNLNKVPSEVVPN-------------------PKGTPS-PPCIVSTVPYH 215

Query: 537 SHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
                A++Q        T  + T    SP +K+T T     + PQ           PG  
Sbjct: 216 CVTPMASIQSGVASLPQTTPTTTLAIASPQVKDT-TISSVLISPQ----------NPGSL 264

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTI-----VSPKHPEVTLPHPDQV 651
             + PVSP   + L    L +        G +T P   I     ++P H           
Sbjct: 265 SLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLG 324

Query: 652 QTQHSHLTRATVQPLDLGFTIT------PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDK 705
           QT  S L+  TV+ + +  + T       +S+    PS   +  A     P V  P  DK
Sbjct: 325 QTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFP-VVAPSVDK 383

Query: 706 GQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGH 765
           G +  S +T +    L++  + +  PTT +    +   T   P    + +    TT    
Sbjct: 384 GPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPLVAQMPVSSVGTTPLVV 443

Query: 766 STALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKAS 825
           +       AP      +   S    +GP + +EP   + +         A  AP+E    
Sbjct: 444 TNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALV-------MAPVAPKEPSTQ 496

Query: 826 TSTNI 830
            +T +
Sbjct: 497 VATTL 501



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 145/695 (20%), Positives = 224/695 (32%), Gaps = 161/695 (23%)

Query: 178 QTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSE-QVGPSQFHLEPET-----QNPETLE 231
           +T+  ++SST   YPS        +S  PP PS  +V P+     P       + P T+ 
Sbjct: 337 KTISVDHSSTGASYPSQ-------RSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTIS 389

Query: 232 DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPA--LPPESSMESLTLPNHEVSVQPPGEDQ 289
            I  S                 PS     A +  L P +S+   + PN            
Sbjct: 390 SITCS-----------------PSGSLNVATSFSLSPTTSLILKSSPN------------ 420

Query: 290 AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP-PV 348
           A YH P +   P     T     TN    + A        P      AT    P+   P+
Sbjct: 421 ATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAA--------PTTTFEVATCVSPPMSSGPI 472

Query: 349 SPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQP-PEH-----HEVTVSPPGHH-- 400
           S +E     +    PV P E S +V ++L    +P  P PE        V V  P     
Sbjct: 473 SNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDL 532

Query: 401 QTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQH---- 456
           QT           P    LT   +P+         + + +  S S +   P + +     
Sbjct: 533 QTVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAK 592

Query: 457 ---GGP-PLLPESSEEAGPLAVQQET------SFQSPE------------------PINN 488
              G P P+   +S    PL V          S+  P+                  P+ +
Sbjct: 593 KSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLES 652

Query: 489 ENP---SPTQQEAAAEHPQTAE---EGESSLTHQEAPAQ------TPEFP----NVVVAQ 532
            +P   +PT  +  + +  TA    EG  SL  +  P +       P  P    N  VA 
Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAP 712

Query: 533 PPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN-- 590
            P+++    AT+        + PE        P    +P+ PP    P  +   G+++  
Sbjct: 713 SPQNTCAPLATL-------VLAPE-------IPKSVPSPSLPPAGTPPGTKKVDGISHTS 758

Query: 591 ------------PTPGQDQAQHPVSPSVTVQLLD----LGLTITPE------------PT 622
                       PT     +    S      L D    LG++++P+            P 
Sbjct: 759 ALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD 818

Query: 623 TEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
           T +G+ ++P   + +   PE +L    Q        T +   P   G   TP ++T + P
Sbjct: 819 TPIGNLSSPVSPVEASFLPENSLSF--QGSKDSPATTHSPTPPSPKG-APTPSAVTPLSP 875

Query: 683 STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE 742
               +     P    V LP   +G A     T A  Q   L +T ++       P+P   
Sbjct: 876 KGVTLPPKETPTPSVVNLPFPKEGPA-----TPAPKQAPALSMTSSSPKKARATPAPKGI 930

Query: 743 ETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHP 777
             S  P          P +  G         AP P
Sbjct: 931 PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 71/334 (21%), Positives = 119/334 (35%), Gaps = 24/334 (7%)

Query: 44   KDPLQLTSN-PLGPPESWSSHSSHFPRESPHAPTLPADPWDFDHLGP--SASSEMPAPPQ 100
            K PL   +  PL P +  SS ++   +++ H+P  P  P +     P  +A+ E   P  
Sbjct: 1727 KGPLSTVAPAPLLPVQKDSSKTAK-GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKP 1785

Query: 101  ESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSL 160
            ES            S    P  P     +   +      Q+ LP SP  + + P++  + 
Sbjct: 1786 ESA-----------SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAP 1834

Query: 161  AEIIGIARQLST-PQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFH 219
            A+   +   +   P S     Q+   +  TP  + +P  +   S + P      G S   
Sbjct: 1835 ADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIP--VPTPSAKQPVTKNNKG-SGTE 1891

Query: 220  LEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEP-SSMQQEAPALPPESSMESLTLPN- 277
             + +   PE  E   + +  Q+A       ++EEP S  +Q         +M  L L   
Sbjct: 1892 SDSDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQV 1951

Query: 278  ---HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVE 334
                 V+++           P++   PA     +  E   E  S QAQ     +F  + E
Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGE 2011

Query: 335  PSATQQEAPIEPPVSPMEHELSISEQQQPVQPSE 368
              +  QE    P V     E  + E    V+  E
Sbjct: 2012 AVSNIQENTQTPTVQEESEEEEVDETGVEVKDIE 2045


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 73.6 bits (179), Expect = 8e-13
 Identities = 146/697 (20%), Positives = 235/697 (33%), Gaps = 89/697 (12%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           R L    S           T T + +S   + + KS   P        + +      +  
Sbjct: 249 RPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEES 308

Query: 228 ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287
           E  ED +++    +   +  + ++E  S+ +       P          N+  S   P E
Sbjct: 309 EKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTE 368

Query: 288 DQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
           ++      N T+ PA        EPT   E +  +   P           T  E     P
Sbjct: 369 NRERTANENTTLSPA--------EPTENRERTANENTAPFPAGPTENREMTANENTTLFP 420

Query: 348 VSPMEHELSISEQQQPVQPSESSREVESSLTQQET--PGQPPEH-------HEVTVSPPG 398
             P EH    + +     P+E +   E +  +  T  P +P EH       ++ T S   
Sbjct: 421 AEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTSSSA 480

Query: 399 HHQTHHLDSP--SVSVKPPDVQLTIAAEPSAEVGTS------LVHQEATARLSGSGNDVE 450
               H   +P  + +  P   + T   E +A   T+        ++E TA    + + VE
Sbjct: 481 ESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLSPVE 540

Query: 451 P------PAIQHGGP-PLLPESSEEAGPLAVQQETSFQSP-------EPINNENPSPTQQ 496
           P       A +   P P  P  + +  P A ++ TS  +         P+ NEN +P+  
Sbjct: 541 PTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPA 600

Query: 497 EAAAEHPQTAEE--GESSLTHQEAPAQTP---EFPNVVVAQPPEHSHLTQATVQPLDLGF 551
           E      +TA E    S     E   +TP   E     +A+P E+    Q T    +   
Sbjct: 601 EPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENG---QRTPFANEKTT 657

Query: 552 TITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQL- 610
           + + E     E +P   E  T  P +   + R      N TP       P  P+   ++ 
Sbjct: 658 SSSAEPTEHEERTPLANENTTPSPAEPT-ENRERTANENTTPS------PAGPTENREMT 710

Query: 611 LDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLG- 669
            +   T+ P   TE    TA ++T  SP  P     +  +    +   T ++ +P + G 
Sbjct: 711 ANEKTTLFPAEPTENRERTANEKTTSSPAEP---TENGQRTPFANEKTTSSSAEPTEHGE 767

Query: 670 --------FTITPKSMTEVEPSTALMTTAPPPGHP---------EVTLP----PSDKGQ- 707
                    T++P   TE    TA   T P P  P         E T P    P++ G  
Sbjct: 768 RTPLANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDR 827

Query: 708 --AQHSHLTQATVQPLD--LELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET 763
               +   T +  +P +         + TT     PT     T   +      P   TE 
Sbjct: 828 TPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTEN 887

Query: 764 GHSTALEKTT----APHPDRVQSLHRSLTEVTGPPTE 796
              TA EKTT     P  +R  + +   T     PTE
Sbjct: 888 RERTANEKTTQFPAEPTENRESTANEKTTPFPAEPTE 924



 Score = 65.1 bits (157), Expect = 3e-10
 Identities = 190/976 (19%), Positives = 318/976 (32%), Gaps = 181/976 (18%)

Query: 50   TSNPLGPPESWSSHSSHFPRESPHAPT-------------LPADPWDFDHLGPSASSEM- 95
            T +P  P E+    ++     SP  PT              PA P +   +  + ++ + 
Sbjct: 360  TPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLF 419

Query: 96   PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQE---RLPVSPKKLKK 152
            PA P E  E       T   A  +P E  +  A++        P E   R P +  K   
Sbjct: 420  PAEPTEHGERTANENTTPSPA--EPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTS 477

Query: 153  DPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSL-PPELRVKSDEPPGPSE 211
              A+     E   +A + +TP   + T   E ++ +   PS   P E R  +        
Sbjct: 478  SSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENRETTANEKTTLS 537

Query: 212  QVGPSQFH----LEPETQNP-ETLEDIQSSSLQQE----APAQLPQLLEEEPSSMQQEAP 262
             V P++       E  T +P E  E+ Q +    E    + A+  +  E  P + +   P
Sbjct: 538  PVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTP 597

Query: 263  ALPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKPADVEVTITSEPT------- 313
            + P E +       N + +  P  P E+     L N    P+  E T   + T       
Sbjct: 598  S-PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEKT 656

Query: 314  --NETESSQAQQETPI----QFPEEVEPS----ATQQEAPIEPPVSPMEHELSISEQQQP 363
              +  E ++ ++ TP+      P   EP+     T  E     P  P E+    + ++  
Sbjct: 657  TSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKTT 716

Query: 364  VQPSESSREVESSLTQQET--PGQPPEHHEVT-----------VSPPGHHQTHHLDSPSV 410
            + P+E +   E +  ++ T  P +P E+ + T             P  H +   L + + 
Sbjct: 717  LFPAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENT 776

Query: 411  SVKPP-----------DVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGP 459
            ++ P            +      AEP+     +       +    + N    P       
Sbjct: 777  TLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTT 836

Query: 460  PLLPESSE--EAGPLAVQQETSFQSP-------EPINNENPSPTQQEAAAEHPQTAEEGE 510
            P L E +E  +  P A ++ TS  +         P+ NEN + +  E      +TA E  
Sbjct: 837  PSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKT 896

Query: 511  SSL-------THQEAPAQTPEFP---------------NVVVAQPPEHSHLTQATV---- 544
            +             A  +T  FP                +  A+P EH  +T   V    
Sbjct: 897  TQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDENL 956

Query: 545  -----------QPLDLGFTIT----PESMTEVEL--------SPTMKETPTQPPKKVV-- 579
                       +P D+  T+      ES T  E+        S T   T +    ++   
Sbjct: 957  QAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEITMS 1016

Query: 580  -----------PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE---- 624
                         +R    V+ P      A        TV       T+T  PTT     
Sbjct: 1017 SAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTASTSG 1076

Query: 625  VGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
              ++TA + T+       +T      V TQ S +   +V            + T  + +T
Sbjct: 1077 SKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVP--------HTATKTPTDTTT 1128

Query: 685  ALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT----------- 733
            A ++   P  +    +  +       +  T  T        TIT+ PTT           
Sbjct: 1129 ASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTSKITAG 1188

Query: 734  -EVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTG 792
             E+  + TT+  +T           E    T   T  E TTA  P        + T  TG
Sbjct: 1189 SEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVP--------TTTSTTG 1240

Query: 793  PPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEMLSCIDLNPEQRL 852
                      S+  +   T +++ T  E  +ASTS    E+ T    M + +    E  +
Sbjct: 1241 SENTGHHTVSSVPTTVFATASESSTGSETTRASTSAT--EVTTA---MTTAMTTGSETAV 1295

Query: 853  RQVPVPEPNTHNGTFT 868
                 P   T +G  T
Sbjct: 1296 VSTKAPVTTTQSGFST 1311



 Score = 55.8 bits (133), Expect = 2e-07
 Identities = 160/806 (19%), Positives = 282/806 (34%), Gaps = 133/806 (16%)

Query: 50   TSNPLGPPESWSSHSSHFPRESPHAPTLPADPWDF-DHLGPSASSEMPAPPQESTENLVP 108
            TS+   P E    H    P  + +    PA+P +  +      ++  PA P E+ E    
Sbjct: 657  TSSSAEPTE----HEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTAN 712

Query: 109  FLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQE---RLPVSPKKLKKDPAQRWSLAEIIG 165
               T   A  +P E  +  A+++       P E   R P + +K     A+     E   
Sbjct: 713  EKTTLFPA--EPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTP 770

Query: 166  IARQLST--PQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
            +A + +T  P    +  +   +   TP+P+         ++E   PS    P+Q   E  
Sbjct: 771  LANENTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPS----PAQ-PTENG 825

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQ 283
             + P   E    S  +     +      E+ +S   E     P    E   L N   +  
Sbjct: 826  DRTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAE-----PTEHAERTPLANENTTSS 880

Query: 284  P--PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQE 341
            P  P E++        T  PA        EPT   ES+  ++ TP  FP E         
Sbjct: 881  PAEPTENRERTANEKTTQFPA--------EPTENRESTANEKTTP--FPAE--------- 921

Query: 342  APIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQ 401
                                    P+E +RE  ++     +P +P EH E+T      + 
Sbjct: 922  ------------------------PTE-NREWTANENTTLSPAEPTEHEEMTPLMVDENL 956

Query: 402  THHLDSPSVSVKPPDVQLTIAAEPSAEVGT-------SLVHQEATARLSGSGNDVEPPAI 454
                   S + +P D+  T+A+   +E  T       S +   ATA  + S    E   +
Sbjct: 957  QAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASE-ITM 1015

Query: 455  QHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
                 P+   + E      ++  T+   P   +      T       +  T+    S++T
Sbjct: 1016 SSAAIPVSSTAYE-----TIRFSTAVSEPVTASILALESTLAFTTVSNTTTS----STVT 1066

Query: 515  HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQP 574
                 A T    N    +    + +++ T+  +      T  + T V  + ++  T T+ 
Sbjct: 1067 SVPTTASTSGSKNTTACE----ATMSETTIAAITASEDTTVSTQTSVIAAESVPHTATKT 1122

Query: 575  P--------KKVVPQLRVYQGVTN-PTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEV 625
            P           VP+      +T+ P+   + A   ++   T        TIT  PTT  
Sbjct: 1123 PTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMT---TASKTTTTSTITSLPTTVF 1179

Query: 626  GHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE---- 681
               T   +     + P  T    D   T  S  T+A+   ++   +  P +  E      
Sbjct: 1180 ---TTTSKITAGSEIP--TASTTDSATTAIS--TKASGTTVESAPSTAPPTPAETTTASV 1232

Query: 682  PSTALMTTAPPPGHPEVTLPPSD-----KGQAQHSHLTQATVQPLDLELTITTKPTTEVK 736
            P+T   T +   GH  V+  P+         +  S  T+A+    ++   +TT  TT  +
Sbjct: 1233 PTTTSTTGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSATEVTTAMTTAMTTGSE 1292

Query: 737  PSPTTEE---TSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGP 793
             +  + +   T+TQ       ++P  TT    ST    +T  + + + S+ +S+      
Sbjct: 1293 TAVVSTKAPVTTTQSGFSTATVMPAKTTTASVSTT--ASTTLYQNTIDSVAKSV------ 1344

Query: 794  PTELEPAQDSLVQSESYTQNKALTAP 819
                 P  DS + S+S T +K ++ P
Sbjct: 1345 -----PTMDSTIASKSTTLSKIVSVP 1365



 Score = 40.0 bits (92), Expect = 0.009
 Identities = 69/332 (20%), Positives = 114/332 (34%), Gaps = 49/332 (14%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +             
Sbjct: 171 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGK------------- 217

Query: 535 EHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG 594
              H+T A            P+S      S T K T T+   K    L       + T  
Sbjct: 218 --KHITPA------------PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTST 263

Query: 595 QDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH--STAPKRTIVSPKHPEVTLPHPDQVQ 652
                   S   T    + G + T + +T      + A K T  +   PE +    D   
Sbjct: 264 S-------SHKTTTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRT 316

Query: 653 TQHSH--LTRATVQPLDLGFTITPKSMTE--VEPSTALMTTAPPPGHPEVTLPPSDKGQA 708
           T  S   LT+ T    ++  TI+   +T+   EP+     TA     P    P  ++ + 
Sbjct: 317 TVASDKLLTKTT---KNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRERT 373

Query: 709 QHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTA 768
            + + T +  +P +       + T      PT  E      +    + P   TE G  TA
Sbjct: 374 ANENTTLSPAEPTENRERTANENTAPFPAGPT--ENREMTANENTTLFPAEPTEHGERTA 431

Query: 769 LEKTTAPHPDRVQSLHRSLTEVTGP----PTE 796
            E TT    +  +   R+  E T P    PTE
Sbjct: 432 NENTTPSPAEPTEHGERTANENTTPSPAEPTE 463



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 43/182 (23%), Positives = 76/182 (41%), Gaps = 17/182 (9%)

Query: 638 PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE--PSTALMTTAPPPGH 695
           P+ P+ T  H  +     +  ++ T +P     TI  KS T+    P T+   ++     
Sbjct: 134 PELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKD 193

Query: 696 PEV----TLPPSD-----KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE--ET 744
           P +    ++ P+D     K  A   H+T A    ++   + T K T   K   T    E 
Sbjct: 194 PMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEK 253

Query: 745 STQPPDLGLAIIPEPTTE---TGHSTALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQ 801
           S    D       + TT    +G+S   +K+T+  P+++ +  ++  + TG P E E  +
Sbjct: 254 SMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS-FPEKITAASKTTYKTTGTPEESEKTE 312

Query: 802 DS 803
           DS
Sbjct: 313 DS 314


>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
          Length = 1142

 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 100/381 (26%), Positives = 139/381 (36%), Gaps = 74/381 (19%)

Query: 44  KDPLQLTSNPLGPPESWSSHS-------------SHFPRESPHAPTLPADPWDFDHLGPS 90
           + PLQ+   P  PPE  ++HS             S  P   P +P     P   D L P 
Sbjct: 511 QSPLQI---PQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSP-----PQGEDSLSPH 562

Query: 91  ASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKL 150
                P  P +  ++L P        GE  L P  F  S    +D +SP    P SP + 
Sbjct: 563 Y---FPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPL-YFPQSPLQG 618

Query: 151 KKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPS 210
           ++  +   S   I   +   S PQS              P  S  PPE  V+S   P  S
Sbjct: 619 EEFQSSLQSPVSICSSSTPSSLPQS-------------FPESSQSPPEGPVQS---PLHS 662

Query: 211 EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQL-LEEEPSSMQQEAPALPPESS 269
            Q  P   H +   Q+PE+  + + S     +P Q+PQ  LE E S      P  PPE  
Sbjct: 663 PQSPPEGMHSQSPLQSPESAPEGEDSL----SPLQIPQSPLEGEDSLSSLHFPQSPPE-- 716

Query: 270 MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
            E    P H     P GED        +++  +   +++   P +  ES Q+  E P Q 
Sbjct: 717 WEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSL---PQSFPESPQSPPEGPAQS 773

Query: 330 PEEVEPSA-----------TQQEAPIEPPVSPMEHEL------------SISEQQQPVQP 366
           P +   S+           +  E+P  PP  P +  L            S   Q  PV  
Sbjct: 774 PLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSPVSS 833

Query: 367 SESSREVESSLTQQETPGQPP 387
             SS     S +  E+P Q P
Sbjct: 834 FPSSTSSSLSKSSPESPLQSP 854



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 98/443 (22%), Positives = 156/443 (35%), Gaps = 84/443 (18%)

Query: 216 SQFHLEPETQNPETLEDIQSSSLQ----QEAPAQLPQLLEEEPSSMQQ------EAPALP 265
           S F   PE  +  T E    S LQ        + L  +L+  P S Q       ++P   
Sbjct: 387 SLFQSSPERTH-STFEGFPQSPLQIPMTSSFSSTLLSILQSSPESAQSAFEGFPQSPLQI 445

Query: 266 PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQE- 324
           P SS  S TL    +S+     ++ +         P  + V+ +S  +      Q+  E 
Sbjct: 446 PVSSSFSYTL----LSLFQSSPERTHSTFEGFPQSPLQIPVSSSSSSSTLLSLFQSSPEC 501

Query: 325 ----------TPIQFPE------------EVEPSATQQEAPIEP---PVSPMEHELSISE 359
                     +P+Q P+            ++ PS  + E  + P   P SP + E S+S 
Sbjct: 502 TQSTFEGFPQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSP 561

Query: 360 QQQPVQPSESSREVESSLTQQETPGQPP-EHHEVTVSPP-GHHQTHHLDSPSVSVKPPDV 417
              P  P +    +      Q   G+     H    SPP G      L  P   ++  + 
Sbjct: 562 HYFPQSPPQGEDSLSPHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQGEEF 621

Query: 418 QLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQE 477
           Q ++ +  S    ++     ++   S   +   PP     GP   P  S ++ P  +  +
Sbjct: 622 QSSLQSPVSICSSST----PSSLPQSFPESSQSPPE----GPVQSPLHSPQSPPEGMHSQ 673

Query: 478 TSFQSPE--PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEF-----PNVVV 530
           +  QSPE  P   ++ SP Q       PQ+  EGE SL+    P   PE+     P    
Sbjct: 674 SPLQSPESAPEGEDSLSPLQI------PQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFP 727

Query: 531 AQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN 590
             PP+      +   P+ +       S T + L  +  E+P  PP+              
Sbjct: 728 QFPPQGEDFQSSLQSPVSI-----CSSSTSLSLPQSFPESPQSPPE-------------- 768

Query: 591 PTPGQDQAQHPVSPSVTVQLLDL 613
             P Q   Q PVS   +  L  L
Sbjct: 769 -GPAQSPLQRPVSSFFSYTLASL 790



 Score = 50.4 bits (119), Expect = 7e-06
 Identities = 93/370 (25%), Positives = 130/370 (35%), Gaps = 61/370 (16%)

Query: 173 PQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDE---------PPGPSEQVGPSQFHLEPE 223
           PQS  Q  Q+     +T  P  + P L    D          PP   + + P  F     
Sbjct: 510 PQSPLQIPQSPPEGENTHSPLQIVPSLPEWEDSLSPHYFPQSPPQGEDSLSPHYF----- 564

Query: 224 TQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP--ESSMESLTLPNHEVS 281
            Q+P   ED  S       P   PQ  + E S      P  PP  E SM  L  P   + 
Sbjct: 565 PQSPPQGEDSLS-------PHYFPQSPQGEDSLSPHYFPQSPPQGEDSMSPLYFPQSPLQ 617

Query: 282 VQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQE 341
            +   E Q+    P      +    T +S P +  ESSQ+  E P+Q             
Sbjct: 618 GE---EFQSSLQSPVSICSSS----TPSSLPQSFPESSQSPPEGPVQ------------- 657

Query: 342 APIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVS------ 395
           +P+  P SP E   S    Q P+Q  ES+ E E SL+  + P  P E  +   S      
Sbjct: 658 SPLHSPQSPPEGMHS----QSPLQSPESAPEGEDSLSPLQIPQSPLEGEDSLSSLHFPQS 713

Query: 396 -PPGHHQTHHLDSPSVSVKPPDVQLTIAAEPS-AEVGTSLVHQEATARLSGSGNDVEPPA 453
            P        L  P    +  D Q ++ +  S     TSL   ++      S     PP 
Sbjct: 714 PPEWEDSLSPLHFPQFPPQGEDFQSSLQSPVSICSSSTSLSLPQSFPESPQS-----PPE 768

Query: 454 IQHGGPPLLPESSEEAGPLAVQQETSFQSPE-PINNENPSPTQQEAAAEHPQTAEEGESS 512
                P   P SS  +  LA   ++S +SP+ P      SP Q   ++    T+     S
Sbjct: 769 GPAQSPLQRPVSSFFSYTLASLLQSSHESPQSPPEGPAQSPLQSPVSSFPSSTSSSLSQS 828

Query: 513 LTHQEAPAQT 522
                 P+ T
Sbjct: 829 SPVSSFPSST 838



 Score = 40.4 bits (93), Expect = 0.007
 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 13/129 (10%)

Query: 266 PESSMESLTLPNHEVSVQ-PPGED-QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQ 323
           P + M SL   + E     P GED Q+   +P  + +  D    + S P + +E   +  
Sbjct: 7   PTAGMPSLLQSSSESPQSCPEGEDSQSPLQIPQSSPESDDTLYPLQS-PQSRSEGEDSSD 65

Query: 324 ETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETP 383
             P+Q P    P     ++P++ P S  E +    + Q P+Q S+SS E + SL+  E  
Sbjct: 66  --PLQRP----PEGKDSQSPLQIPQSSPEGD----DTQSPLQNSQSSPEGKDSLSPLEIS 115

Query: 384 GQPPEHHEV 392
             PPE  +V
Sbjct: 116 QSPPEGEDV 124



 Score = 37.4 bits (85), Expect = 0.061
 Identities = 62/281 (22%), Positives = 108/281 (38%), Gaps = 34/281 (12%)

Query: 459 PPLLPESSEEAGPLAVQQE-TSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQE 517
           P    E  + + PL    E    QSP  I   +P     ++  ++ Q++ EG+ SL+  E
Sbjct: 54  PQSRSEGEDSSDPLQRPPEGKDSQSPLQIPQSSPEGDDTQSPLQNSQSSPEGKDSLSPLE 113

Query: 518 APAQTPEFPNV-VVAQPPEHSHLT-------QATVQPLDLGFTITPESMTEVELSPTMKE 569
                PE  +V    Q P  S  +       Q++ +     F   P+S+ ++ +S     
Sbjct: 114 ISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIPVSAASSS 173

Query: 570 TPTQPPKKVVPQLRVYQGVTNPTPG------QDQAQHPVSPSVTVQLLDLGLTITPEPT- 622
           T           + ++Q     T        Q   Q PVS S +  LL +    +PE T 
Sbjct: 174 T----------LVSIFQSSPESTQSPFEGFPQSPLQIPVSRSFSSTLLSI-FQSSPERTQ 222

Query: 623 -TEVGHSTAPKRTIVSPKHPEVTL----PHPDQVQTQHSHLTRATVQ-PLDLGFTITPKS 676
            T  G + +P +  VSP      L       ++ Q+      ++++Q P+   F+ T  S
Sbjct: 223 STFEGFAQSPLQIPVSPSSSSTLLSLFQSFSERTQSTFEGFAQSSLQIPVSPSFSSTLVS 282

Query: 677 MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
           + +  P     T    P  P + +P S    +    L Q++
Sbjct: 283 LFQSSPERTQSTFEGFPQSP-LQIPVSSSSSSTLLSLFQSS 322



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 55/245 (22%), Positives = 87/245 (35%), Gaps = 43/245 (17%)

Query: 457 GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQ 516
           G P LL  SSE   P +  +    QSP  I   +P         + PQ+  EGE S    
Sbjct: 10  GMPSLLQSSSES--PQSCPEGEDSQSPLQIPQSSPESDDTLYPLQSPQSRSEGEDS---- 63

Query: 517 EAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVE--LSPTMKETPTQP 574
             P Q          +PPE     + +  PL +     P+S  E +   SP      +  
Sbjct: 64  SDPLQ----------RPPE----GKDSQSPLQI-----PQSSPEGDDTQSPLQNSQSSPE 104

Query: 575 PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTIT----------PEPTTE 624
            K  +  L + Q        Q   Q+P S   +  LL +  +            P+   +
Sbjct: 105 GKDSLSPLEISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQ 164

Query: 625 VGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ-PLDLGFTITPKSMTEVEPS 683
           +  S A   T+VS     +    P+  Q+      ++ +Q P+   F+ T  S+ +  P 
Sbjct: 165 IPVSAASSSTLVS-----IFQSSPESTQSPFEGFPQSPLQIPVSRSFSSTLLSIFQSSPE 219

Query: 684 TALMT 688
               T
Sbjct: 220 RTQST 224



 Score = 31.6 bits (70), Expect = 3.3
 Identities = 47/215 (21%), Positives = 85/215 (39%), Gaps = 35/215 (16%)

Query: 493 PTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFT 552
           P+  ++++E PQ+  EGE S +  + P  +PE               +  T+ PL     
Sbjct: 12  PSLLQSSSESPQSCPEGEDSQSPLQIPQSSPE---------------SDDTLYPLQ---- 52

Query: 553 ITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPV-----SPSVT 607
            +P+S +E E S    + P +      P L++ Q     +P  D  Q P+     SP   
Sbjct: 53  -SPQSRSEGEDSSDPLQRPPEGKDSQSP-LQIPQS----SPEGDDTQSPLQNSQSSPEGK 106

Query: 608 VQLLDLGLTITPEPTTEVGHSTA-PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ-P 665
             L  L ++ +P    +V      P  +  S     +    P+  Q+      ++ +Q P
Sbjct: 107 DSLSPLEISQSPPEGEDVQSPLQNPASSFFSSALLSIFQSSPESTQSPFEGFPQSVLQIP 166

Query: 666 LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTL 700
           +    + T  S+ +  P +   T +P  G P+  L
Sbjct: 167 VSAASSSTLVSIFQSSPES---TQSPFEGFPQSPL 198


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 70.9 bits (172), Expect = 5e-12
 Identities = 131/665 (19%), Positives = 231/665 (34%), Gaps = 102/665 (15%)

Query: 132   DLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPY 191
             ++ +K+ P ++ P      K+ PA+   + + I +  ++  P+  +           T  
Sbjct: 10444 EISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP--------PTKV 10495

Query: 192   PSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
             P  LPP+  V   + P P  +        +PE   P+  E  +    +++ P   P+  E
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAK--------KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 252   EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV--EVTIT 309
               P+ + +   A  PE  +     P  E    PP         P +   P +V  E  + 
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPE---SPP---------PEVPEAPKEVVPEKKVP 10595

Query: 310   SEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISE---------- 359
             + P  + E       TP++ PE  +    +++ P+ PP  P      + E          
Sbjct: 10596 AAPPKKPEV------TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649

Query: 360   -----QQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSP----PGHHQTHHLDSPSV 410
                    +P  P     E    +  +E P +  E  E    P    P         +P+V
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709

Query: 411   SVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPE------ 464
               K P++      E   EV    V ++    +     +  P  +      ++PE      
Sbjct: 10710 VAKKPELPPVKVPEVPKEV----VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 465   SSEEAGPLAVQQETSFQSPEPINNENPS-PTQQEAAAEHPQTAEEGESSLTHQE-APAQT 522
                E  P  V +       +P+  E P+ P  + A +  P+  EE E     +E AP + 
Sbjct: 10766 KKPEVPPAKVPEVPK----KPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821

Query: 523   PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQL 582
                P   VA+  E      A  +         P+ +   +  P +K+    PPK+  P+ 
Sbjct: 10822 KPVP---VAEEEEPEVPPPAVPE--------EPKKIIPEKKVPVIKKPEAPPPKEPEPEK 10870

Query: 583   RVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHP- 641
              + +    P P       P  P   V+     L   P+           K  +   K P 
Sbjct: 10871 VIEKPKLKPRP---PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPG 10927

Query: 642   ---EVTLPHPDQVQTQHSHLTRATV---QPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
                +V    P++       +   +V   +P +    + PK + +V+   A+    PP   
Sbjct: 10928 GEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVK-KPAVPEPPPPKPV 10986

Query: 696   PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAI 755
              EV +P   K + +    T+       + L     P  E KP P  E  + +PP     +
Sbjct: 10987 EEVEVPTVTKRERKIPEPTKVPEIKPAIPL-----PAPEPKPKPEAEVKTIKPP----PV 11037

Query: 756   IPEPT 760
              PEPT
Sbjct: 11038 EPEPT 11042



 Score = 67.0 bits (162), Expect = 7e-11
 Identities = 173/834 (20%), Positives = 278/834 (33%), Gaps = 162/834 (19%)

Query: 89    PSASSEMPAPPQESTENLVPFLDTWDSAG--EQPLEP--------------EQFLASQQD 132
             P+   E+P  P+E    L+P  +    A   E P +P              E   A   +
Sbjct: 9975  PAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE 10034

Query: 133   LKDKLSPQERLPV-SPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPY 191
             +  K  P++++PV +PKK++  PA+                P+  K+ +  E   T  P 
Sbjct: 10035 VPKKPVPEKKVPVPAPKKVEAPPAK---------------VPEVPKKLIPEEKKPTPVPK 10079

Query: 192   PSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
                 PP    K  EP      +   +  L  E   PE           +E   +  ++L 
Sbjct: 10080 KVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPE-----------EEVLPEEEEVLP 10128

Query: 252   EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE--DQAYYHLPNITVKPADVEVTIT 309
             EE   + +E   LP E       +P  E  V P  E   +    +P   V P        
Sbjct: 10129 EEEEVLPEEEEVLPEEEE-----IPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPV 10183

Query: 310   SEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSES 369
               P  E +    +++  I   EE  P A   E P       +E +  I  +++ V P E 
Sbjct: 10184 PAPVPEIKKKVTEKKVVIPKKEEAPP-AKVPEVP-----KKVEEKRIILPKEEEVLPVEV 10237

Query: 370   SREVESS-LTQQETPGQPPEHHEV-TVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSA 427
             + E E   ++++E P +PP   EV  V+PP   +   +   +V   P  V   + A P A
Sbjct: 10238 TEEPEEEPISEEEIPEEPPSIEEVEEVAPP---RVPEVIKKAVPEAPTPVPKKVEA-PPA 10293

Query: 428   EVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESS------------------EEA 469
             +V   +  ++    +        PPA     P  +PE                    EE 
Sbjct: 10294 KVSKKIPEEKVPVPVQ---KKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKGRTVLEEK 10350

Query: 470   GPLAVQQETSFQSP---EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQ---------- 516
               +A +QE   +     E +  E     ++E   E  +  EEGE     +          
Sbjct: 10351 VSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVE 10410

Query: 517   --------------------------EAPAQTPEFPNVVVAQPPEHSHLTQATVQPL--- 547
                                       +AP + PE    ++      + +      P    
Sbjct: 10411 EEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVP 10470

Query: 548   DLGFTITPESMTEVELSPTMKETPTQ---PPKKVVPQLRV----YQGVTNPTPGQDQAQH 600
             ++   I  E    V   P +  T      PPK+VVP+ +V     +    P P   +A  
Sbjct: 10471 EVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPK 10530

Query: 601   PVSPSVTVQL-----LDLGLTITPE-PTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQ 654
              V P   V +      ++  T  PE P   V     P+     P+ P   +P   +    
Sbjct: 10531 EVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVP 10590

Query: 655   HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
                +  A  +  ++     P++  EV P   +    PPP  PEV  PP            
Sbjct: 10591 EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKV--PVPPPKKPEV--PP------------ 10634

Query: 715   QATVQPLDLELTITTKPTTEV---KPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEK 771
               T  P   ++ +  K   E    KP     E   +P ++ L   P    E     A  +
Sbjct: 10635 --TKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQ 10692

Query: 772   TTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKA-LTAPEEQKA 824
              T P    V    +    V     EL P +   V  E   + K  L  P++ +A
Sbjct: 10693 VTVPPKKPVP--EKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEA 10744



 Score = 61.2 bits (147), Expect = 4e-09
 Identities = 158/792 (19%), Positives = 270/792 (34%), Gaps = 99/792 (12%)

Query: 122   EPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQ 181
             E E+F+  ++ L + + P+  +P    ++KK   ++      + I ++   P ++   + 
Sbjct: 10163 EEEEFVPEEEVLPE-VKPKVPVPAPVPEIKKKVTEKK-----VVIPKKEEAPPAKVPEVP 10216

Query: 182   NEYSSTDTPYPSS---LPPELRVKSDEPPGPSEQVG--PSQFHLEPETQNPETLEDIQSS 236
              +        P     LP E+  + +E P   E++   P       E   P   E I+ +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276

Query: 237   SLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPN 296
                 EAP  +P+ +E  P+ + ++ P       ++    P  +V   P    +    +P 
Sbjct: 10277 V--PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK 10334

Query: 297   ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIEPPVSPME--- 352
                 P     T+  E      S   +QE  ++   E+E   A  +E P E     +E   
Sbjct: 10335 KEAVPPAKGRTVLEEKV----SVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390

Query: 353   -----HELS--ISEQQQPVQPSESSREVE--------SSLTQQETPGQPPEHHEVT--VS 395
                  HE+   I  +Q  V+      +V           +   E P  PP+  E++  + 
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKII 10450

Query: 396   PPGHHQTHHLDSPSVSVKPPDVQLTIAAE-----------PSAEVGTSLVHQEATARLSG 444
             PP    T  +       K P+V   I  E           P  +V   L  +E       
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV 10510

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA-AEHP 503
                 V P       PP +PE+ +E  P     E     P P   E P     E   A  P
Sbjct: 10511 P---VPPAKKPEAPPPKVPEAPKEVVP-----EKKVPVPPPKKPEVPPTKVPEVPKAAVP 10562

Query: 504   QTAEEGESSLTHQEAPAQTPEFPNVVV------AQPPEHSHLTQATVQPLDLGFTITPES 557
             +           +  P + PE P  VV      A PP+   +T   V   +    + PE 
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVP--EAPKEVVPEK 10620

Query: 558   MTEVELSPTMKETPT---QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS-VTVQLLDL 613
                V      +  PT   + PK  VP+ +V + +  P P     +    P  V ++    
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPA 10679

Query: 614   GLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTI- 672
              +   PEP      +  PK+ +   K P V    P+    +   + +  V    +   + 
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739

Query: 673   ---------TPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
                       P+   EV P   +        PP   PEV   P  + +       +A   
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESP 10799

Query: 720   PLDL-ELTITTKPTTEV-----KPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTT 773
             P ++ E      P  E+     KP P  EE   + P   +   P+          ++K  
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859

Query: 774   AP---HPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL---TAPEEQKASTS 827
             AP    P+  + + +   +   PP    P ++ +   E   Q KA+     PE+ +    
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV--KEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 828   TNICELCTCGDE 839
               +  L   G E
Sbjct: 10918 VELTPLKVPGGE 10929



 Score = 58.9 bits (141), Expect = 2e-08
 Identities = 145/723 (20%), Positives = 253/723 (34%), Gaps = 102/723 (14%)

Query: 123   PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQT-LQ 181
             PE+ + +    K+K+ P    P  P++ KK   ++    ++I +   L    +++   + 
Sbjct: 9589  PEKKVPAPVPKKEKVPP----PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQIT 9644

Query: 182   NEYSSTDTPYPSSLPPELRVKSDEPPG-PSEQVGPSQFHLEP--ETQNPETLEDIQSSSL 238
              E            PP+ RV  +     P E+V      L+P  E + P  + + +   +
Sbjct: 9645  QEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV----LKLKPKREEEPPAKVTEFRKRVV 9700

Query: 239   QQE-----APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
             ++E     AP + PQ ++E     ++E           + TL    VSVQ   E + Y  
Sbjct: 9701  KEEKVSIEAPKREPQPIKEVTIMEEKE----------RAYTLEEEAVSVQREEEYEEY-- 9748

Query: 294   LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEH 353
                   +  D +     EPT E +  +  +E   +  EE E   T+ E PI  PV P   
Sbjct: 9749  ------EEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPI--PVKP--- 9797

Query: 354   ELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVK 413
                + E+  P +P     +V      +E    P         P    +   +    + + 
Sbjct: 9798  ---VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRIS 9854

Query: 414   PPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA 473
                 +     EP+A+V        A  ++     +V PP         +PE  +E  P  
Sbjct: 9855  ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPV-------RVPEVPKELEP-- 9905

Query: 474   VQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA----PAQTPEFPNVV 529
               +E +F+       E  +  ++    E  +   E E  +T +E     P + PE P   
Sbjct: 9906  --EEVAFE------EEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKP 9957

Query: 530   VAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVT 589
             V +  +   + +    P        P  + EV   P  K     P K+  P  +V +   
Sbjct: 9958  VPEEKKPVPVPKKKEAP--------PAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPK 10009

Query: 590   NPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPD 649
              P P +++   PV   V            P    EV     P++ +  P   +V  P P 
Sbjct: 10010 KPVP-EEKVPVPVPKKVEA---------PPAKVPEVPKKPVPEKKVPVPAPKKVEAP-PA 10058

Query: 650   QVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQ 709
             +V      L     +P     T  PK + E  P        P P    V LP  ++   +
Sbjct: 10059 KVPEVPKKLIPEEKKP-----TPVPKKV-EAPPPKVPKKREPVP--VPVALPQEEEVLFE 10110

Query: 710   HSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGL----AIIPEPTTETGH 765
                + +  V P + E+    +     +     EE    P +  +      +PE       
Sbjct: 10111 EEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPEEEEFVPE 10170

Query: 766   STALE--KTTAPHPDRVQSLHRSLTE---VTGPPTELEPAQDSLVQSESYTQNKALTAPE 820
                L   K   P P  V  + + +TE   V     E  PA+   V  +   + K +  P+
Sbjct: 10171 EEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKK--VEEKRIILPK 10228

Query: 821   EQK 823
             E++
Sbjct: 10229 EEE 10231



 Score = 43.1 bits (100), Expect = 0.001
 Identities = 158/834 (18%), Positives = 278/834 (33%), Gaps = 152/834 (18%)

Query: 72    PHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQ 131
             P  P LP  P   + + P    +   PP       VP     +     P+  ++  A  +
Sbjct: 9286  PKVPELPEKPAP-EEVAPVPIPKKVEPPAPKVPE-VPKKPVPEEKKPVPVPKKEPAAPPK 9343

Query: 132   --DLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDT 189
               ++  K  P+E++PV   K K+ P  +               P+ QK  +  E  +  T
Sbjct: 9344  VPEVPKKPVPEEKIPVPVAKKKEAPPAK--------------VPEVQKGVVTEEKITIVT 9389

Query: 190   PYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQL 249
                 S PP +      P  P ++V             PE  + +     +   P ++P L
Sbjct: 9390  QREESPPPAV------PEIPKKKV-------------PEERKPVPRKEEEVPPPPKVPAL 9430

Query: 250   LEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK-PADVEVTI 308
                 P     E     P    +    P  EVS +   E++ +     ++   P  VEVT 
Sbjct: 9431  ----PKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVT- 9485

Query: 309   TSEPTNETESSQAQQETPIQFP--------EEVEPSATQQEAPIEPPVSPMEHELSISEQ 360
               E + E E S +++E  +           EE E   T+ E   EP    +E +L I  +
Sbjct: 9486  RHEVSAEEEWSYSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISK 9545

Query: 361   QQPVQPSESSREVESSLT---------QQETPGQPPE---------------HHEVTVSP 396
             +   +P+E +   E  +          ++  P + PE                 +  V P
Sbjct: 9546  RVEAEPAEVTERQEKKIVLKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPP 9605

Query: 397   PGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPPA-IQ 455
             P   +      P   V P  +++              + QE    ++ +  +  P A + 
Sbjct: 9606  PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVP 9665

Query: 456   HGGPPLLPESS--------EEAGPLAV---------QQETSFQSPEPINNENPSPTQQEA 498
                   +PE          EE  P  V         +++ S ++P+      P P ++  
Sbjct: 9666  EEPKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKVSIEAPK----REPQPIKEVT 9721

Query: 499   AAEHPQ---TAEEGESSLTHQEAPAQTPEF---------PNVVVAQPPEHSHLTQATVQP 546
               E  +   T EE   S+  +E   +  E+         P     Q  E+        + 
Sbjct: 9722  IMEEKERAYTLEEEAVSVQREEEYEEYEEYDYKEFEEYEPTEEYDQYEEYEEREYERYEE 9781

Query: 547   LDLGFTITPESMTEVELSP--TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP 604
              +  +   PE    V+  P   +   P  PP KV+ +    + V  P P + +   P  P
Sbjct: 9782  HE-EYITEPEKPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVP 9840

Query: 605   SVTVQLLD--LGLTITPEPTTEVGHSTA-----PKRTIVSPKHP----EVTLP------- 646
                 ++ +  + ++IT     +V    A     PKR +   K P    EV  P       
Sbjct: 9841  EEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVP 9900

Query: 647   ---HPDQVQTQH---SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP-----PPGH 695
                 P++V  +    +H+    V+  +       + +TE E    +    P     P   
Sbjct: 9901  KELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPE 9960

Query: 696   PEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK-------PTTEVKPSPTTEETSTQP 748
              +  +P   K +A  + + +   +P +    +  K          EV   P  EE    P
Sbjct: 9961  EKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020

Query: 749   PDLGLAIIPEPTTETGHSTALE-KTTAPHPDRVQSLHRSLTEVTGPPTELEPAQ 801
                 +   P    E       E K   P P +V++    + EV   P +L P +
Sbjct: 10021 VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEV---PKKLIPEE 10071



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 72/355 (20%), Positives = 126/355 (35%), Gaps = 59/355 (16%)

Query: 44    KDPLQLTSNPLGPPESWSSHSSHF-PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
             K PL +   P  PP           P +    P  P  P       P+   E+P  P   
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP-------PAKVPEVPKKPVLE 10785

Query: 103   TENLVPFLDTWDSAG----EQPLE--PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQ 156
              +  VP  +  +S      E+P E  PE+ +A +++    ++ +E   V P  + ++P +
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845

Query: 157   RWSLAEIIGIARQLSTPQSQ---KQTLQNEYSSTDTPYPSSLPPELRVKS---------- 203
                  ++  I +  + P  +   ++ ++        P P   PP+  VK           
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905

Query: 204   ----DEP-------------PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
                 ++P             PG  ++V       +PE +    L+ +     ++E P   
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 10965

Query: 247   PQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEV 306
             P+ LE+       E P   P   +E  T+   E  +  P +      +P I  KPA    
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK------VPEI--KPAIPLP 11017

Query: 307   TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQ 361
                 +P  E E    +       P  VEP  T   AP+  PV   + E    +++
Sbjct: 11018 APEPKPKPEAEVKTIK-------PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEE 11065



 Score = 36.2 bits (82), Expect = 0.14
 Identities = 83/408 (20%), Positives = 144/408 (35%), Gaps = 32/408 (7%)

Query: 333 VEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEV 392
           ++ +A QQ     PP  P +      + + P  PS +++   + L +Q++P   P  H  
Sbjct: 241 IDGAAGQQLPHKTPPRIPPK-----PKSRSPTPPSIAAK---AQLARQQSPS--PIRHSP 290

Query: 393 TVSPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATARLSGSGNDVEPP 452
           +   P  H      SP  SV P      I+  P   V + L+ ++  A    +G +V PP
Sbjct: 291 S---PVRHVRAPTPSPVRSVSPA---ARISTSPIRSVRSPLLMRKTQASTVATGPEVPPP 344

Query: 453 AIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
             Q G       SS EA        TS Q       E     Q++        A    S+
Sbjct: 345 WKQEG----YVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAAASVSA 400

Query: 513 LTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITP--ESMTEVELSPTMKET 570
                A A         V Q  + S      V  +D+     P   ++ +     T    
Sbjct: 401 SASYAAEAVATGAKE--VKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRTTTTAV 458

Query: 571 PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL---GLTITPEPTTEVGH 627
             QP ++ V +      VT      D+A+     S T +++      + +T E   +   
Sbjct: 459 HIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQIRKETE 518

Query: 628 ST-APKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
            T  PK  I + K  E      +++  +   +T+  ++  +   T     +     ST L
Sbjct: 519 KTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQ-ETEITAASMVVVATAKSTKL 577

Query: 687 MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTE 734
            T    PG  E T    D+    +  + + T + +  ++ + T    E
Sbjct: 578 ETV---PGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKE 622


>gi|226437579 NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 178/782 (22%), Positives = 275/782 (35%), Gaps = 109/782 (13%)

Query: 89  PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
           PS+ S + A    S      F D  D     P+ P   L  Q  L  ++   E  P+SP+
Sbjct: 274 PSSESSLSADSSSSWGQEGHFFDL-DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPE 332

Query: 149 KLKKDP-AQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPP 207
           + +++  A      ++ G   + ST  S  Q+L      +D      +      + D   
Sbjct: 333 EEEEEAVADPDPGGDLAGEGEEDSTSASFLQSL------SDLSITEGMDEAFAFRDDTSA 386

Query: 208 GPSEQVGPSQFHLEPE---TQNPETLEDIQSSSLQ--QEAPAQLPQLLEEEPSSMQQEAP 262
             S+    S    + E   +  P     +   S+Q  +E      + L+ +  ++     
Sbjct: 387 ASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVE 446

Query: 263 ALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQ 322
           A P  S   +      E+  +   E  A       TV P  ++V     P  + E   A 
Sbjct: 447 AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVA----PGLQVEV--AT 500

Query: 323 QETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQET 382
           + TP    EE + +A Q+ A +  P              QP Q   S    + S+T ++ 
Sbjct: 501 RVTPQAGEEETDSTAGQESAAMAMP--------------QPSQEGISEILGQESVTAEKL 546

Query: 383 PGQPPEHHEVTV---SPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
           P  P E   +T+   SP    +   LD PS   + P    TI    + E  T       T
Sbjct: 547 P-TPQEETSLTLCPDSPQNLKEEGGLDLPSG--RKPVAAATIVPRQAKEDLTLPQDSAMT 603

Query: 440 ARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
             L     D+           ++ + +EE   L + Q++    P P+ +   S   +  A
Sbjct: 604 PPLPLQDTDLSSAPKPVAAATIVSQQAEEG--LTLPQDSVMTPPLPLQDTELSSAPKPVA 661

Query: 500 AEHPQTAEEGESSLTHQEAPAQTPEFP--NVVVAQPPEHSHLTQATVQPLDLGFTITPES 557
           A     +++ E  LT  +  A TP  P  +  ++  P+         Q  + G T+  +S
Sbjct: 662 AA-TLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720

Query: 558 MTEVELSPTMKETPTQPPKKVVPQLRVYQ------------GVTNPTPGQD----QAQHP 601
                L P      +  PK V     V Q             +T P P QD     A  P
Sbjct: 721 AMTPPL-PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 779

Query: 602 VSPSVTV-QLLDLGLTIT-------PEPTTEVGHSTAPK----RTIVSPKHPE-VTLPHP 648
           V+ +  V Q  + GLT+        P P  +   S+APK     TIVS +  E +TLP  
Sbjct: 780 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 839

Query: 649 DQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA 708
                       A   PL L  T     ++      A  T         +TLP       
Sbjct: 840 S-----------AMTPPLPLQDT----DLSSAPKPVAAATPVSQQAEEGLTLP------- 877

Query: 709 QHSHLTQATVQPL-DLELTITTKPTTEVKP-SPTTEETSTQPPDLGLAIIPEPTTETGHS 766
           Q S +T     PL D +L+   KP     P S   EE  T P D  +   P P  +TG +
Sbjct: 878 QDSAMTPPL--PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA-PLPLQDTGPT 934

Query: 767 TALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKAST 826
           +  E      P  +Q+         G     EP   ++ Q E         APEE+ A+ 
Sbjct: 935 SGPEPLAVATPQTLQA-------EAGCAPGTEPVA-TMAQQEVGEALGPRPAPEEKNAAL 986

Query: 827 ST 828
            T
Sbjct: 987 PT 988



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 174/820 (21%), Positives = 269/820 (32%), Gaps = 176/820 (21%)

Query: 90   SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK 149
            SA+  MP P QE    ++         G++ +  E+    Q++    L P      SP+ 
Sbjct: 519  SAAMAMPQPSQEGISEIL---------GQESVTAEKLPTPQEETSLTLCPD-----SPQN 564

Query: 150  LKKD-----PAQRWSLAEIIGIARQ----LSTPQSQKQTLQNEYSSTD---TPYPSSLPP 197
            LK++     P+ R  +A    + RQ    L+ PQ    T       TD    P P +   
Sbjct: 565  LKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624

Query: 198  ELRVKSDEP---PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEP 254
             +  +++E    P  S    P        +  P+ +      S Q E    LPQ     P
Sbjct: 625  IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 684

Query: 255  SSMQQE-----------APALPPESSMESLTLPNHEVSVQP-PGEDQAYYHLPNITVKPA 302
                Q+           A  L  + + E LTLP       P P +D      P    KP 
Sbjct: 685  PLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP----KPV 740

Query: 303  DVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQ 362
                 +         S QA++   +     + P    Q+  +     P+     +S+Q +
Sbjct: 741  AAATLV---------SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 791

Query: 363  P--VQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
                 P +S+      L   +    P      T+      +   L   S    P  +Q T
Sbjct: 792  EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 851

Query: 421  -IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETS 479
             +++ P      + V Q+A   L+                  LP+ S    PL +Q    
Sbjct: 852  DLSSAPKPVAAATPVSQQAEEGLT------------------LPQDSAMTPPLPLQDTDL 893

Query: 480  FQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
              +P+P+           AA    Q AEEG   LT  +  A T   P            L
Sbjct: 894  SSAPKPV----------AAATPVSQQAEEG---LTLPQDSAMTAPLPLQDTGPTSGPEPL 940

Query: 540  TQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQ 599
              AT Q L            E   +P  +   T   ++V   L        P P +  A 
Sbjct: 941  AVATPQTL----------QAEAGCAPGTEPVATMAQQEVGEALG-----PRPAPEEKNAA 985

Query: 600  HPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPE-VTLPHP-----DQVQT 653
             P  P      LD      P+P  E G   A +    S    E ++LP P     +++  
Sbjct: 986  LPTVPEPAA--LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAE 1043

Query: 654  QHSHLTR-----ATVQPLDLGFTITPKSMT-EVE---------------PSTAL-----M 687
              S   R     A     D     +P+  T EVE               P +AL     +
Sbjct: 1044 ALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREV 1103

Query: 688  TTAPPPGHPEVT----LPPS--DKGQAQHSHLTQATVQPLDLELTITTKPTTEV------ 735
              APP   PEV+    L P+  ++G +  S         +  E ++ + P + V      
Sbjct: 1104 PDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSL 1163

Query: 736  ------KPSPTTEETSTQP-PDLGLAII-----------------PEPTTETGHSTALEK 771
                   P+PT+  TS QP P LGL  +                 PE   +   ST +++
Sbjct: 1164 DRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDR 1223

Query: 772  TTAPHPDRVQSLHRSLTEVTGPPTEL---EPAQDSLVQSE 808
               P P    +L  +      PP      +P +DS+   E
Sbjct: 1224 PLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEE 1263



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 73/330 (22%), Positives = 112/330 (33%), Gaps = 51/330 (15%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQE---RLPV 145
            PS   + P  P  S         T   A   PLEP      Q   +D +  +E    L +
Sbjct: 1217 PSTPVDRPLGPDPSAPG------TLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGL 1270

Query: 146  SPKKLKKDPAQRWSLAEIIGIARQLSTP-----QSQKQTLQNEYSSTDTPY-------PS 193
             P +    PA     A + G  + L T            L  + +S D          P 
Sbjct: 1271 PPPQAGVQPAA----AAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPC 1326

Query: 194  SLPPELRVKSDEPPGPSEQVGPSQFHLEP--ETQNPETLEDIQSSSLQQEAPAQL----- 246
             +PP    +S  P GP     P Q   E   E  +P  L   Q S    E+ A+L     
Sbjct: 1327 QVPPPSGPQS--PAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI 1384

Query: 247  --PQLLE---EEPSSMQQEAPALPPES--------SMESLTLPNHE----VSVQPPGEDQ 289
              PQ ++   + P+   +E  A   +S        +M  L L   +    +++Q      
Sbjct: 1385 LAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNIL 1444

Query: 290  AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVS 349
                 P++   PA     +  E   E  S Q  +    +F    EPSA   E+   P V 
Sbjct: 1445 FVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVR 1504

Query: 350  PMEHELSISEQQQPVQPSESSREVESSLTQ 379
                E    E+++  +     R++E  + Q
Sbjct: 1505 LECKEEEEEEEEEVDEAGLELRDIELVMAQ 1534



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 73/341 (21%), Positives = 122/341 (35%), Gaps = 63/341 (18%)

Query: 86   HLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPV 145
            H G  A    P  PQ+ T  +       ++  E  L+P   LA +   +  L     +P 
Sbjct: 1059 HTGDGAK---PDSPQKETLEV-------ENQQEGGLKP---LAQEHGPRSALGGAREVPD 1105

Query: 146  SPKKLKKDPAQRWSLAEIIGIARQ------LSTPQSQKQTLQNEYSSTDTPYPSSLPPEL 199
            +P     + +Q    A ++  AR+       STP+    +     +S D+   SS+    
Sbjct: 1106 APPAACPEVSQ----ARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVS 1161

Query: 200  RVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ 259
             +    P  P+    P+       +Q PE +  + S     E P+ L   L + P ++ +
Sbjct: 1162 SLDRGCPDAPAPTSAPT-------SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAK 1214

Query: 260  EAPALPPE----------SSMESLTLPNHEVSV----QPPGEDQAY---------YHLPN 296
              P+ P +           ++    LP  E       Q P ED               P 
Sbjct: 1215 GQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1274

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP--VSPMEHE 354
              V+PA   V+ T++P            +P+  P+     A      I PP  V P    
Sbjct: 1275 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGP 1334

Query: 355  LSISEQQQPVQPSESSREVESSLTQQETP-----GQPPEHH 390
             S +  Q    P +  +E E SL ++++P     GQ  + H
Sbjct: 1335 QSPAGPQGLSAPEQ--QEDEDSL-EEDSPRALGSGQHSDSH 1372


>gi|239743134 PREDICTED: NAC alpha domain containing [Homo sapiens]
          Length = 1562

 Score = 69.7 bits (169), Expect = 1e-11
 Identities = 178/782 (22%), Positives = 275/782 (35%), Gaps = 109/782 (13%)

Query: 89  PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
           PS+ S + A    S      F D  D     P+ P   L  Q  L  ++   E  P+SP+
Sbjct: 274 PSSESSLSADSSSSWGQEGHFFDL-DFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPE 332

Query: 149 KLKKDP-AQRWSLAEIIGIARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPP 207
           + +++  A      ++ G   + ST  S  Q+L      +D      +      + D   
Sbjct: 333 EEEEEAVADPDPGGDLAGEGEEDSTSASFLQSL------SDLSITEGMDEAFAFRDDTSA 386

Query: 208 GPSEQVGPSQFHLEPE---TQNPETLEDIQSSSLQ--QEAPAQLPQLLEEEPSSMQQEAP 262
             S+    S    + E   +  P     +   S+Q  +E      + L+ +  ++     
Sbjct: 387 ASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVE 446

Query: 263 ALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQ 322
           A P  S   +      E+  +   E  A       TV P  ++V     P  + E   A 
Sbjct: 447 AAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVA----PGLQVEV--AT 500

Query: 323 QETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQPVQPSESSREVESSLTQQET 382
           + TP    EE + +A Q+ A +  P              QP Q   S    + S+T ++ 
Sbjct: 501 RVTPQAGEEETDSTAGQESAAMAMP--------------QPSQEGISEILGQESVTAEKL 546

Query: 383 PGQPPEHHEVTV---SPPGHHQTHHLDSPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
           P  P E   +T+   SP    +   LD PS   + P    TI    + E  T       T
Sbjct: 547 P-TPQEETSLTLCPDSPQNLKEEGGLDLPSG--RKPVAAATIVPRQAKEDLTLPQDSAMT 603

Query: 440 ARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
             L     D+           ++ + +EE   L + Q++    P P+ +   S   +  A
Sbjct: 604 PPLPLQDTDLSSAPKPVAAATIVSQQAEEG--LTLPQDSVMTPPLPLQDTELSSAPKPVA 661

Query: 500 AEHPQTAEEGESSLTHQEAPAQTPEFP--NVVVAQPPEHSHLTQATVQPLDLGFTITPES 557
           A     +++ E  LT  +  A TP  P  +  ++  P+         Q  + G T+  +S
Sbjct: 662 AA-TLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDS 720

Query: 558 MTEVELSPTMKETPTQPPKKVVPQLRVYQ------------GVTNPTPGQD----QAQHP 601
                L P      +  PK V     V Q             +T P P QD     A  P
Sbjct: 721 AMTPPL-PLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKP 779

Query: 602 VSPSVTV-QLLDLGLTIT-------PEPTTEVGHSTAPK----RTIVSPKHPE-VTLPHP 648
           V+ +  V Q  + GLT+        P P  +   S+APK     TIVS +  E +TLP  
Sbjct: 780 VAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQD 839

Query: 649 DQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA 708
                       A   PL L  T     ++      A  T         +TLP       
Sbjct: 840 S-----------AMTPPLPLQDT----DLSSAPKPVAAATPVSQQAEEGLTLP------- 877

Query: 709 QHSHLTQATVQPL-DLELTITTKPTTEVKP-SPTTEETSTQPPDLGLAIIPEPTTETGHS 766
           Q S +T     PL D +L+   KP     P S   EE  T P D  +   P P  +TG +
Sbjct: 878 QDSAMTPPL--PLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTA-PLPLQDTGPT 934

Query: 767 TALEKTTAPHPDRVQSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKAST 826
           +  E      P  +Q+         G     EP   ++ Q E         APEE+ A+ 
Sbjct: 935 SGPEPLAVATPQTLQA-------EAGCAPGTEPVA-TMAQQEVGEALGPRPAPEEKNAAL 986

Query: 827 ST 828
            T
Sbjct: 987 PT 988



 Score = 51.6 bits (122), Expect = 3e-06
 Identities = 174/820 (21%), Positives = 269/820 (32%), Gaps = 176/820 (21%)

Query: 90   SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK 149
            SA+  MP P QE    ++         G++ +  E+    Q++    L P      SP+ 
Sbjct: 519  SAAMAMPQPSQEGISEIL---------GQESVTAEKLPTPQEETSLTLCPD-----SPQN 564

Query: 150  LKKD-----PAQRWSLAEIIGIARQ----LSTPQSQKQTLQNEYSSTD---TPYPSSLPP 197
            LK++     P+ R  +A    + RQ    L+ PQ    T       TD    P P +   
Sbjct: 565  LKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAAT 624

Query: 198  ELRVKSDEP---PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEP 254
             +  +++E    P  S    P        +  P+ +      S Q E    LPQ     P
Sbjct: 625  IVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTP 684

Query: 255  SSMQQE-----------APALPPESSMESLTLPNHEVSVQP-PGEDQAYYHLPNITVKPA 302
                Q+           A  L  + + E LTLP       P P +D      P    KP 
Sbjct: 685  PLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAP----KPV 740

Query: 303  DVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQQQ 362
                 +         S QA++   +     + P    Q+  +     P+     +S+Q +
Sbjct: 741  AAATLV---------SQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAE 791

Query: 363  P--VQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420
                 P +S+      L   +    P      T+      +   L   S    P  +Q T
Sbjct: 792  EGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDT 851

Query: 421  -IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETS 479
             +++ P      + V Q+A   L+                  LP+ S    PL +Q    
Sbjct: 852  DLSSAPKPVAAATPVSQQAEEGLT------------------LPQDSAMTPPLPLQDTDL 893

Query: 480  FQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
              +P+P+           AA    Q AEEG   LT  +  A T   P            L
Sbjct: 894  SSAPKPV----------AAATPVSQQAEEG---LTLPQDSAMTAPLPLQDTGPTSGPEPL 940

Query: 540  TQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQ 599
              AT Q L            E   +P  +   T   ++V   L        P P +  A 
Sbjct: 941  AVATPQTL----------QAEAGCAPGTEPVATMAQQEVGEALG-----PRPAPEEKNAA 985

Query: 600  HPVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPE-VTLPHP-----DQVQT 653
             P  P      LD      P+P  E G   A +    S    E ++LP P     +++  
Sbjct: 986  LPTVPEPAA--LDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAE 1043

Query: 654  QHSHLTR-----ATVQPLDLGFTITPKSMT-EVE---------------PSTAL-----M 687
              S   R     A     D     +P+  T EVE               P +AL     +
Sbjct: 1044 ALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREV 1103

Query: 688  TTAPPPGHPEVT----LPPS--DKGQAQHSHLTQATVQPLDLELTITTKPTTEV------ 735
              APP   PEV+    L P+  ++G +  S         +  E ++ + P + V      
Sbjct: 1104 PDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSL 1163

Query: 736  ------KPSPTTEETSTQP-PDLGLAII-----------------PEPTTETGHSTALEK 771
                   P+PT+  TS QP P LGL  +                 PE   +   ST +++
Sbjct: 1164 DRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDR 1223

Query: 772  TTAPHPDRVQSLHRSLTEVTGPPTEL---EPAQDSLVQSE 808
               P P    +L  +      PP      +P +DS+   E
Sbjct: 1224 PLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEE 1263



 Score = 33.5 bits (75), Expect = 0.88
 Identities = 73/330 (22%), Positives = 112/330 (33%), Gaps = 51/330 (15%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQE---RLPV 145
            PS   + P  P  S         T   A   PLEP      Q   +D +  +E    L +
Sbjct: 1217 PSTPVDRPLGPDPSAPG------TLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGL 1270

Query: 146  SPKKLKKDPAQRWSLAEIIGIARQLSTP-----QSQKQTLQNEYSSTDTPY-------PS 193
             P +    PA     A + G  + L T            L  + +S D          P 
Sbjct: 1271 PPPQAGVQPAA----AAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPC 1326

Query: 194  SLPPELRVKSDEPPGPSEQVGPSQFHLEP--ETQNPETLEDIQSSSLQQEAPAQL----- 246
             +PP    +S  P GP     P Q   E   E  +P  L   Q S    E+ A+L     
Sbjct: 1327 QVPPPSGPQS--PAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDI 1384

Query: 247  --PQLLE---EEPSSMQQEAPALPPES--------SMESLTLPNHE----VSVQPPGEDQ 289
              PQ ++   + P+   +E  A   +S        +M  L L   +    +++Q      
Sbjct: 1385 LAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNIL 1444

Query: 290  AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVS 349
                 P++   PA     +  E   E  S Q  +    +F    EPSA   E+   P V 
Sbjct: 1445 FVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVR 1504

Query: 350  PMEHELSISEQQQPVQPSESSREVESSLTQ 379
                E    E+++  +     R++E  + Q
Sbjct: 1505 LECKEEEEEEEEEVDEAGLELRDIELVMAQ 1534



 Score = 30.4 bits (67), Expect = 7.4
 Identities = 73/341 (21%), Positives = 122/341 (35%), Gaps = 63/341 (18%)

Query: 86   HLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPV 145
            H G  A    P  PQ+ T  +       ++  E  L+P   LA +   +  L     +P 
Sbjct: 1059 HTGDGAK---PDSPQKETLEV-------ENQQEGGLKP---LAQEHGPRSALGGAREVPD 1105

Query: 146  SPKKLKKDPAQRWSLAEIIGIARQ------LSTPQSQKQTLQNEYSSTDTPYPSSLPPEL 199
            +P     + +Q    A ++  AR+       STP+    +     +S D+   SS+    
Sbjct: 1106 APPAACPEVSQ----ARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVS 1161

Query: 200  RVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ 259
             +    P  P+    P+       +Q PE +  + S     E P+ L   L + P ++ +
Sbjct: 1162 SLDRGCPDAPAPTSAPT-------SQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAK 1214

Query: 260  EAPALPPE----------SSMESLTLPNHEVSV----QPPGEDQAY---------YHLPN 296
              P+ P +           ++    LP  E       Q P ED               P 
Sbjct: 1215 GQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQ 1274

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP--VSPMEHE 354
              V+PA   V+ T++P            +P+  P+     A      I PP  V P    
Sbjct: 1275 AGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGP 1334

Query: 355  LSISEQQQPVQPSESSREVESSLTQQETP-----GQPPEHH 390
             S +  Q    P +  +E E SL ++++P     GQ  + H
Sbjct: 1335 QSPAGPQGLSAPEQ--QEDEDSL-EEDSPRALGSGQHSDSH 1372


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 68.6 bits (166), Expect = 2e-11
 Identities = 140/629 (22%), Positives = 216/629 (34%), Gaps = 89/629 (14%)

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
            D Q++ L+ +APA   +     P  + Q+     PES + SL L   E+ + P G +   
Sbjct: 725  DYQATLLEDQAPAHFHRNF---PEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVE--- 778

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIE---PPV 348
                  TV     E+ + S    E E   +     I FPE+    A   E  +E   P +
Sbjct: 779  ------TVNDTKPELNVASSEGGEMERRDSDSFLNI-FPEKQVTKAGNTEPVLEEWIPVL 831

Query: 349  SPMEHELSISEQQQPVQPSESSREVESSLTQQETPG--------QPPEHHEVTVSPPGHH 400
                   ++   +  +  +  S E  +S+     P          P  H ++ V+     
Sbjct: 832  QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSL 891

Query: 401  QTHHLDS-----------PSVSVKPPDVQLTIAA----EPSAEVGTSLVHQEATARLSGS 445
            +   + +           P+V+V  P+    +AA    E +A    + + QE  + ++G 
Sbjct: 892  EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951

Query: 446  GNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHPQ 504
              +    AI     P+  E     GP  V   T+  +P EP        T +E A+  P 
Sbjct: 952  SPEWAALAIT---VPITEEDGTPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPAS--PA 1004

Query: 505  TAEEGESSLTHQEAPAQTPEFP-NVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVEL 563
             A       T   A   TPE P +   A PP     + A   P       TPE  T    
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-------TPEEPTSPAA 1057

Query: 564  SPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP-EP 621
            +    E PT P   V  P+         PTP     + P SP+  V         TP EP
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVP--------TPEEP 1104

Query: 622  TTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
            T+       P+     P  P   +P P++  +       A   P +  F        E  
Sbjct: 1105 TSPAAAVPTPE----EPASPAAAVPTPEEPASP----AAAVPTPEEPAFPAPAVPTPEES 1156

Query: 682  PSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK----PTTEVKP 737
             S A+    P          P+    A  + +     +P     ++ T      T E   
Sbjct: 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFT 1216

Query: 738  SPTTE-ETSTQPPDLGLAII--PEPTTETGHSTALEKTTAPHPDRVQSLHRSLTEVTGPP 794
            SP     TS +P  L  A+    EPT+       LE+ T+     V +     +     P
Sbjct: 1217 SPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTS-SAAAVLTPEELSSPAASVP 1275

Query: 795  TELEPAQDSLVQS---ESYTQNKALTAPE 820
            T  EPA  +   S   E  +   A+  PE
Sbjct: 1276 TPEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 94/394 (23%), Positives = 134/394 (34%), Gaps = 66/394 (16%)

Query: 167  ARQLSTPQSQKQTLQNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
            A ++STP+          ++  TP   + P       +EP  P+  V P +    P    
Sbjct: 991  AVRVSTPEEPASPA----AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAV 1046

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
            P T E+  S +     P        EEP+S     P  P E +  +  +P  E    P  
Sbjct: 1047 P-TPEEPTSPAAAVPTP--------EEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPA- 1095

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
               A    P     PA       + PT E  +S A     +  PEE    A     P EP
Sbjct: 1096 ---AAVPTPEEPTSPA------AAVPTPEEPASPA---AAVPTPEEPASPAAAVPTPEEP 1143

Query: 347  ----PVSPMEHELSISEQQQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQT 402
                P  P   E + +    P  P ES+    S      TP +      V  +       
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPT-PEESA----SPAAAVPTPAESASFAAVVAT------L 1192

Query: 403  HHLDSPSVSVKPPDVQLTIAAE---PSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGP 459
                SP+ SV  P   +    E   P+A V TS    E  A L+ + ++ E P       
Sbjct: 1193 EEPTSPAASVPTPAAMVATLEEFTSPAASVPTS----EEPASLAAAVSNPEEPTSPAAAV 1248

Query: 460  PLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAP 519
            P L E +  A  +   +E S            SP       E P +     S+L    +P
Sbjct: 1249 PTLEEPTSSAAAVLTPEELS------------SPAASVPTPEEPASPAAAVSNLEEPASP 1296

Query: 520  A---QTPEFPNVVVAQ--PPEHSHLTQATVQPLD 548
            A    TPE   +  A    PE   +  A V P++
Sbjct: 1297 AAAVPTPEVAAIPAASVPTPEVPAIPAAAVPPME 1330


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.306    0.124    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,842,678
Number of Sequences: 37866
Number of extensions: 2807913
Number of successful extensions: 15444
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 108
Number of HSP's successfully gapped in prelim test: 1112
Number of HSP's that attempted gapping in prelim test: 9284
Number of HSP's gapped (non-prelim): 4031
length of query: 870
length of database: 18,247,518
effective HSP length: 111
effective length of query: 759
effective length of database: 14,044,392
effective search space: 10659693528
effective search space used: 10659693528
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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