Guide to the Human Genome
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Search of human proteins with 239745376

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo
sapiens]
         (513 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]          1050   0.0  
gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo ...  1050   0.0  
gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo ...  1050   0.0  
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     56   7e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    50   6e-06
gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]               49   8e-06
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       46   7e-05
gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ...    45   1e-04
gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ...    45   1e-04
gi|116256464 hypothetical protein LOC343990 [Homo sapiens]             45   1e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    45   2e-04
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    45   2e-04
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      44   5e-04
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    44   5e-04
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    44   5e-04
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    44   5e-04
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    44   5e-04
gi|13540521 basic helix-loop-helix domain containing, class B, 3...    44   5e-04
gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo ...    43   6e-04
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]            43   6e-04
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]            43   6e-04
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               43   6e-04
gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]            43   8e-04
gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]            43   8e-04
gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]            43   8e-04
gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]            43   8e-04
gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]        42   0.001
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            42   0.002
gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo ...    42   0.002
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     42   0.002

>gi|239756433 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 513

 Score = 1050 bits (2714), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60
           MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR
Sbjct: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60

Query: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120
           HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR
Sbjct: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120

Query: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180
           RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA
Sbjct: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180

Query: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240
           EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP
Sbjct: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240

Query: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300
           QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL
Sbjct: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300

Query: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360
           PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL
Sbjct: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360

Query: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420
           AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV
Sbjct: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420

Query: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480
           HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP
Sbjct: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480

Query: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513
           GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV
Sbjct: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513


>gi|239750970 PREDICTED: hypothetical protein XP_002347634 [Homo
           sapiens]
          Length = 513

 Score = 1050 bits (2714), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60
           MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR
Sbjct: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60

Query: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120
           HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR
Sbjct: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120

Query: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180
           RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA
Sbjct: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180

Query: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240
           EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP
Sbjct: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240

Query: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300
           QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL
Sbjct: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300

Query: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360
           PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL
Sbjct: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360

Query: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420
           AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV
Sbjct: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420

Query: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480
           HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP
Sbjct: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480

Query: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513
           GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV
Sbjct: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513


>gi|239745376 PREDICTED: hypothetical protein XP_002343484 [Homo
           sapiens]
          Length = 513

 Score = 1050 bits (2714), Expect = 0.0
 Identities = 513/513 (100%), Positives = 513/513 (100%)

Query: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60
           MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR
Sbjct: 1   MVFRPQVAPRRMSVSRRSPTMTVRSGLMPYSWDTQSKMKRLGFPMMSAWRWAAISTARTR 60

Query: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120
           HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR
Sbjct: 61  HPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQR 120

Query: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180
           RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA
Sbjct: 121 RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA 180

Query: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240
           EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP
Sbjct: 181 EDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAP 240

Query: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300
           QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL
Sbjct: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300

Query: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360
           PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL
Sbjct: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360

Query: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420
           AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV
Sbjct: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420

Query: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480
           HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP
Sbjct: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480

Query: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513
           GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV
Sbjct: 481 GRREYAPQSFAKTRSRFLGGNTNQPLPGWGIRV 513


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 56.2 bits (134), Expect = 7e-08
 Identities = 100/363 (27%), Positives = 122/363 (33%), Gaps = 47/363 (12%)

Query: 135 GPHAHAGDAHGLQLRGQGWAAQHVGLG--RGGAGQALAQVERGAVG-RAEDLQAGA-GPR 190
           GP  + G+   +   G    +   GL   RG AG    + E+G  G R E    G  G R
Sbjct: 616 GPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLRGEIGNPGRDGAR 675

Query: 191 GAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQG----------LGRARHGGLPAP 240
           GA  A       VG+ G A   GD  +A AAG   P G          +G A   G   P
Sbjct: 676 GAPGA-------VGAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGP 728

Query: 241 QHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGAL 300
             A      +   G +            G V          PP  A  R        G  
Sbjct: 729 AGAAGQPGAKGERGAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSR------GDGGP 782

Query: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWL 360
           P      G A R   P     + PP PP   G      E  RG RGD     +GR G+  
Sbjct: 783 PGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGK-----EGLRGPRGDQ--GPVGRTGEVG 835

Query: 361 AGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAV 420
           A   P F  +    K   GE+     P  PG +G L     +   G     G+     AV
Sbjct: 836 AVGPPGFAGE----KGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVAGAV 891

Query: 421 HWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFP 480
             P  P G    +AG P  GA  P  AV  P   G   + G  R    G    P R   P
Sbjct: 892 GEP-GPLG----IAGPP--GARGPPGAVGSPGVNGAPGEAG--RDGNPGNDGPPGRDGQP 942

Query: 481 GRR 483
           G +
Sbjct: 943 GHK 945



 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 89/324 (27%), Positives = 105/324 (32%), Gaps = 40/324 (12%)

Query: 135 GPHAHAGDAHGLQLRGQGWAAQHVGLG--RGGAGQALAQVERGAVG-RAEDLQAG-AGPR 190
           GP   AG       RG+   A   G     G AGQ  A+ ERGA G + E+   G  GP 
Sbjct: 700 GPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVGPTGPV 759

Query: 191 GAAEAQAPQ-----LLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVA 245
           GAA    P          G  G   + G    A   G   P G+      G P P     
Sbjct: 760 GAAGPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS-----GPPGPPGPAG 814

Query: 246 VEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGA 305
            E  R   G Q   P+G       V   G          A    P      +G L APG 
Sbjct: 815 KEGLRGPRGDQG--PVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGI 872

Query: 306 LIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLP-ALGRPGDWLAGLQ 364
           L  P  R  R L       P      G   P+G A  G  G    P A+G PG  + G  
Sbjct: 873 LGLPGSRGERGL-------PGVAGAVGEPGPLGIA--GPPGARGPPGAVGSPG--VNGAP 921

Query: 365 PAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPV 424
              G     R    G      R   PG +G   +   +  +G           P  H PV
Sbjct: 922 GEAG-----RDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVG-------AAGAPGPHGPV 969

Query: 425 SPAGMGGALAGAPREGAGAPSSAV 448
            PAG  G        G   P+ AV
Sbjct: 970 GPAGKHGNRGETGPSGPVGPAGAV 993



 Score = 37.4 bits (85), Expect = 0.033
 Identities = 81/322 (25%), Positives = 102/322 (31%), Gaps = 58/322 (18%)

Query: 163 GGAGQALAQVERGAVGR-----AEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQ 217
           G  G A A   RG VG      ++      G  G+A  Q P     G +G     G   +
Sbjct: 331 GPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPP----GPSGEEGKRGPNGE 386

Query: 218 ALAAGSQRPQGL-GRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLR 276
           A +AG   P GL G     GLP       V           + P G++  +      G  
Sbjct: 387 AGSAGPPGPPGLRGSPGSRGLPGADGRAGV-----------MGPPGSRGASGPAGVRGPN 435

Query: 277 RRHRRPPAAAARRP---------LLAAARRGALPAPG-----ALIGPAPRARRPLACTFA 322
               RP       P         +  A + G +  PG       IGPA     P    F 
Sbjct: 436 GDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFP 495

Query: 323 NPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPG-DWLAGLQPAFGVKRSLRKCARGES 381
            P  P    G +   G A  G  G     A G PG D   G Q   G +    +  +GE 
Sbjct: 496 GPKGPTGDPGKNGDKGHA--GLAG-----ARGAPGPDGNNGAQGPPGPQGV--QGGKGEQ 546

Query: 382 SAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGA 441
                P F G  GP      V   G+  LHG             PAG  G        GA
Sbjct: 547 GPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGL-------PGPAGPRGERGPPGESGA 599

Query: 442 GAPSSAVPVPLCRGRARDTGPP 463
             P+  +      G    +GPP
Sbjct: 600 AGPTGPI------GSRGPSGPP 615



 Score = 36.2 bits (82), Expect = 0.073
 Identities = 89/336 (26%), Positives = 108/336 (32%), Gaps = 87/336 (25%)

Query: 173 ERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQG---- 228
           ERG VG         GP GA  +       VG  G A  +G        G+  P+G    
Sbjct: 221 ERGRVG-------APGPAGARGSDG----SVGPVGPAGPIGSAGPPGFPGAPGPKGEIGA 269

Query: 229 LGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAAR 288
           +G A   G   P+  V +      VG     P G  P A G+  TG +         AA 
Sbjct: 270 VGNAGPAGPAGPRGEVGLPGLSGPVG-----PPG-NPGANGL--TGAK--------GAAG 313

Query: 289 RPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDH 348
            P +A A    LP P  + GP   A    A      P P    G S   GE   G  G  
Sbjct: 314 LPGVAGAP--GLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEP--GSAGPQ 369

Query: 349 WLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDE 408
                G PG   +G +   G          GE+ +   P  PG RG         S G  
Sbjct: 370 -----GPPGP--SGEEGKRG--------PNGEAGSAGPPGPPGLRG---------SPGSR 405

Query: 409 ALHGV-----TRARPAVHWPVSPAGMGGALAGAPREG----------AGAPSSAVP---- 449
            L G          P       PAG+ G    A R G           G+P +  P    
Sbjct: 406 GLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKE 465

Query: 450 ----VPLCRGRARDTGPPRGSLTGQSREPARGSFPG 481
               +P   GR    GP      G   EP    FPG
Sbjct: 466 GPVGLPGIDGRPGPIGP-----AGARGEPGNIGFPG 496


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 49.7 bits (117), Expect = 6e-06
 Identities = 84/303 (27%), Positives = 103/303 (33%), Gaps = 41/303 (13%)

Query: 175 GAVGRAEDLQAGAGPRGAAE-AQAPQLLGVGSAGLAAVVGD-----EAQALAAGSQRPQG 228
           G+ G    + A A      E A A      G A LAA  G             G  +P G
Sbjct: 132 GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAG 191

Query: 229 LGRAR----HGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPP- 283
            G A+       L    HA A     V+ G   L PL  +P A G V        + PP 
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPL-PKPAAPGTVI-------QTPPF 243

Query: 284 AAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRG 343
             AA  P  AA    A PAP A    AP    P   T A PP  PAG  ++AP       
Sbjct: 244 VGAAAPPAPAAPSPPAAPAPAAPAA-APPPPPPAPATLARPPGHPAGPPTAAPAVPP--- 299

Query: 344 ERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVV 403
                  PA  + G   AG  PA            G+   GA    P         KRVV
Sbjct: 300 -------PAAAQNGG-SAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV 351

Query: 404 SLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPP 463
                A   +  + PA       +     + G   +GA    +AVP P        TG P
Sbjct: 352 QAAPPAAQTLAASGPA-------STAASMVIGPTMQGALPSPAAVPPP---APGTPTGLP 401

Query: 464 RGS 466
           +G+
Sbjct: 402 KGA 404



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 66/268 (24%), Positives = 84/268 (31%), Gaps = 31/268 (11%)

Query: 260 PLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALI---GPAPRARRP 316
           P GA        A G       PP A   RP     +R   P+P   +   GPAP A + 
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKL 126

Query: 317 LACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPA----LGRPGDWLAGLQPAFGVKRS 372
                   PPP    GS AP+  A     G    PA       P    A   P  G    
Sbjct: 127 R-------PPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP- 178

Query: 373 LRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRAR--PAVHWPV-SPAGM 429
                 G      +P  PG    L     +++    A   V+     PA   P+  PA  
Sbjct: 179 ----GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAP 234

Query: 430 GGALAGAPREGAGAPSS-------AVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGR 482
           G  +   P  GA AP +       A P P     A    PP  +    +R P   + P  
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATL--ARPPGHPAGPPT 292

Query: 483 REYAPQSFAKTRSRFLGGNTNQPLPGWG 510
              A    A  ++    G    P P  G
Sbjct: 293 AAPAVPPPAAAQNGGSAGAAPAPAPAAG 320



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 19/37 (51%), Positives = 19/37 (51%), Gaps = 3/37 (8%)

Query: 425 SPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTG 461
           SPAG  GA   AP EGA     A P P   GRAR  G
Sbjct: 66  SPAGAAGAGPAAPAEGA---PGAAPEPPPAGRARPGG 99


>gi|115392133 collagen, type XXIV, alpha 1 [Homo sapiens]
          Length = 1714

 Score = 49.3 bits (116), Expect = 8e-06
 Identities = 96/364 (26%), Positives = 132/364 (36%), Gaps = 63/364 (17%)

Query: 117  GLQRRVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGR--GGAGQALAQVER 174
            GLQ  V P  G + ++  GP    G++ GLQ  G+  A   VG     GG G+   + E 
Sbjct: 996  GLQGDVGP-PGEMGME--GPPGTEGES-GLQ--GEPGAKGDVGTAGSVGGTGEPGLRGEP 1049

Query: 175  GAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARH 234
            GA G  E LQ   G +G            G  GL    G++ +    G   P  LGR+  
Sbjct: 1050 GAPGE-EGLQGKDGLKGVP----------GGRGLPGEDGEKGEMGLPGIIGP--LGRSGQ 1096

Query: 235  GGLPAPQHAVAVEQQRVHVGQQ----RLCPLG--AQPHAAGVVATGLRRRHRRPPAAAAR 288
             GLP P+  V +  QR   G++    ++ P G        G +     +  R    A   
Sbjct: 1097 TGLPGPEGIVGIPGQRGRPGKKGDKGQIGPTGEVGSRGPPGKIGKSGPKGARGTRGAVGH 1156

Query: 289  RPLLAAARRGALPA-------PGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIG-EA 340
              L+       +P        PG    P P+  +      +    PP   G   P+G + 
Sbjct: 1157 LGLMGPDGEPGIPGYRGHQGQPGPSGLPGPKGEKGYPGEDSTVLGPPGPRGEPGPVGDQG 1216

Query: 341  RRGE------RGDHWLPAL----------GRPGDWLAGLQPAFGVKRSL-RKCARGESSA 383
             RGE      +G   +P L          G PGD   G Q   G + S   K  +G    
Sbjct: 1217 ERGEPGAEGYKGHVGVPGLRGATGQQGPPGEPGD--QGEQGLKGERGSEGNKGKKGAPGP 1274

Query: 384  GARPLFPGCRGPLTHWKRVVSLGDEALHGV--TRARPAVHWPVSPAGMGGALAGAPREG- 440
              +P  PG +G L         G +  HG       P    P    G+ G   G  R G 
Sbjct: 1275 SGKPGIPGLQGLLG------PKGIQGYHGADGISGNPGKIGPPGKQGLPGIRGGPGRTGL 1328

Query: 441  AGAP 444
            AGAP
Sbjct: 1329 AGAP 1332


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 99/410 (24%), Positives = 129/410 (31%), Gaps = 57/410 (13%)

Query: 112 HRAHVGLQR------------RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQ-GWAAQHV 158
           HR H GL+                P     A+  LGP    G+   L  +G  G    H 
Sbjct: 301 HRGHKGLEGPKGEVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHG 360

Query: 159 GLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLG--------VGSAGLAA 210
             G+ G    L             ++  AGP GA   + PQ           VGS GL  
Sbjct: 361 MPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPG 420

Query: 211 VVGDEAQALAAGSQRPQGL----GRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPH 266
            +G +    A G     G     G A   G P PQ +   +  R   G   +     +  
Sbjct: 421 AIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAG 480

Query: 267 AAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANP-- 324
             G       +    PP    +R        G    PG +  P P   R        P  
Sbjct: 481 PKGEPGPHGIQGPIGPPGEEGKR--------GPRGDPGTVGPPGPVGERGAPGNRGFPGS 532

Query: 325 ---PPPPAGCGSSAPIGEAR-RGERGDHWLPALGRPG-DWLAGLQPAFGVKRSLRKC--- 376
              P P    G   P+G +  +G +GD   P  G PG     GL    GV+    K    
Sbjct: 533 DGLPGPKGAQGERGPVGSSGPKGSQGDPGRP--GEPGLPGARGLTGNPGVQGPEGKLGPL 590

Query: 377 -ARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAG 435
            A GE      P   G RG      +  S+G     G +   P        AG+ G    
Sbjct: 591 GAPGEDGRPGPPGSIGIRG------QPGSMGLPGPKG-SSGDPGKPGEAGNAGVPGQRGA 643

Query: 436 APREGAGAPSSAVPVPLCRGRARDTGPPRGS----LTGQSREPARGSFPG 481
             ++G   PS  V  P   G   + GPP  +    L G    P  G  PG
Sbjct: 644 PGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLPGPPGPPGEGGKPG 693



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 103/416 (24%), Positives = 134/416 (32%), Gaps = 110/416 (26%)

Query: 149  RGQGWAAQHVGLG--RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSA 206
            RG+      VG    +G  GQ   + E G  G+  D     GP+G A +  P     G  
Sbjct: 836  RGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDA-GSPGPQGLAGSPGPH----GPN 890

Query: 207  GLAAVVGDEAQALAAGSQRPQGL----GRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLG 262
            G+  + G        G+Q P G     G A   G P P  A          G++    L 
Sbjct: 891  GVPGLKGGR------GTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEGPPGLR 944

Query: 263  AQPHAAGVVATGLRRRHRRPPAAAARR----------------PLLAAARRGALPAPG-- 304
              P + G V     R    PP     +                P     +RG +  PG  
Sbjct: 945  GDPGSHGRVGD---RGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQR 1001

Query: 305  ------ALIGPA--PRARRPLACTFANPPPPPAGC-GSSAPIGE---------------- 339
                   L GPA  P    P   T    PP P G  GS+ P+GE                
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061

Query: 340  ---ARRGERGDHW---LPA----------LGRPGDWLAGLQPAFGVKRSLRKCARGESSA 383
                 RG+RGD     LP           +G PGD  AG +   G +  +    R    A
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGD--AGQRGDPGSRGPIGPPGR----A 1115

Query: 384  GARPLFPGCRGPL----THWKRVVSLGDEALHGVT--------------RARPAVHWPVS 425
            G R L PG +GP      H  R    G +   G T              +    +  P  
Sbjct: 1116 GKRGL-PGPQGPRGDKGDHGDRG-DRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFG 1173

Query: 426  PAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPG 481
            P G  G +  + +EG   P   +  P  RG   + GP      G   EP     PG
Sbjct: 1174 PRGPPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGP-----EGPPGEPGPPGPPG 1224


>gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
           sapiens]
          Length = 594

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 67/257 (26%), Positives = 90/257 (35%), Gaps = 43/257 (16%)

Query: 93  VAQGLGELHVAEVRVK------AHHHRAHVGLQRRVQPVAGTLALQWLGPHAHAGDAHGL 146
           +A+GLG    A  RV         H RAH+  +   +   G  A Q              
Sbjct: 350 LAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQ-------------- 395

Query: 147 QLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQ-APQLLGVGS 205
            +R +GW A+    GRG  G+          G  +D      P  AA A+ A Q  G   
Sbjct: 396 -MRREGWGARAKLGGRGVCGKC-------GPGPWDDPARRRNPGAAARAKLAGQRAGRAR 447

Query: 206 AGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQP 265
           A   + VG   +    G+ R    GR    G+  P+            G +   P  ++ 
Sbjct: 448 ARTGSQVGSRGRGWGPGAGRVPSGGRR---GVGNPERW----------GGEAAAPRPSRV 494

Query: 266 HAAGVVATGLRRRHRRPPAAAARRPLLAA-ARRGALPAPGALIGPAPRARRPLACTFANP 324
               + A    R  RR P AAA+R  L     +G    P AL GP PR           P
Sbjct: 495 LLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP 554

Query: 325 PPPPAGCGSSAPIGEAR 341
           P PP      A +  AR
Sbjct: 555 PTPPPARALPAAVASAR 571



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 106/427 (24%), Positives = 142/427 (33%), Gaps = 64/427 (14%)

Query: 65  RTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQRRVQP 124
           R  + A V + + ++  G     AG L+ A  +    VAEV      HR  VGL+     
Sbjct: 171 RHGEPARVAEGQDLLEAGGRH-GAGQLEGALAVAAEQVAEVEAAGGQHRP-VGLEGLALD 228

Query: 125 VAGTLALQ-------WLGPHA--HAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERG 175
             G +A++           H     GD     LR  G AA  +G  RG A   L  +   
Sbjct: 229 HDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSA 288

Query: 176 AV--GRAEDLQ-AGAGPRGAAEAQAPQLL---------GVGSAGLAAVVGDEAQALAAGS 223
           A   GR   L+ AG  PR      A   +         G G+      + DE+       
Sbjct: 289 AAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQ 348

Query: 224 QRPQGLGRARHGGLPAPQHAVAVE-QQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRP 282
              +GLG +   G    +   AV   +R H+ ++     G      G  A  +RR     
Sbjct: 349 SLAEGLGVSPQAGARVGEAREAVTTHERAHLDRE-----GEARARLGQAAAQMRREGWGA 403

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARR 342
            A    R +      G    P     P   AR  LA   A       G         ++ 
Sbjct: 404 RAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTG---------SQV 454

Query: 343 GERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCAR-GESSAGARPLFPGCRGPLTHWKR 401
           G RG  W P  GR            G +R +    R G  +A  RP             R
Sbjct: 455 GSRGRGWGPGAGRVPS---------GGRRGVGNPERWGGEAAAPRP------------SR 493

Query: 402 VVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTG 461
           V+      L  V  AR     P   A     L G   +G GAP SA+P P  R  +   G
Sbjct: 494 VLL---PELPAVDPARDTRREP-DAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPG 549

Query: 462 PPRGSLT 468
            P G  T
Sbjct: 550 EPPGPPT 556


>gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo
           sapiens]
          Length = 594

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 67/257 (26%), Positives = 90/257 (35%), Gaps = 43/257 (16%)

Query: 93  VAQGLGELHVAEVRVK------AHHHRAHVGLQRRVQPVAGTLALQWLGPHAHAGDAHGL 146
           +A+GLG    A  RV         H RAH+  +   +   G  A Q              
Sbjct: 350 LAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQ-------------- 395

Query: 147 QLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQ-APQLLGVGS 205
            +R +GW A+    GRG  G+          G  +D      P  AA A+ A Q  G   
Sbjct: 396 -MRREGWGARAKLGGRGVCGKC-------GPGPWDDPARRRNPGAAARAKLAGQRAGRAR 447

Query: 206 AGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQP 265
           A   + VG   +    G+ R    GR    G+  P+            G +   P  ++ 
Sbjct: 448 ARTGSQVGSRGRGWGPGAGRVPSGGRR---GVGNPERW----------GGEAAAPRPSRV 494

Query: 266 HAAGVVATGLRRRHRRPPAAAARRPLLAA-ARRGALPAPGALIGPAPRARRPLACTFANP 324
               + A    R  RR P AAA+R  L     +G    P AL GP PR           P
Sbjct: 495 LLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP 554

Query: 325 PPPPAGCGSSAPIGEAR 341
           P PP      A +  AR
Sbjct: 555 PTPPPARALPAAVASAR 571



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 106/427 (24%), Positives = 142/427 (33%), Gaps = 64/427 (14%)

Query: 65  RTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQRRVQP 124
           R  + A V + + ++  G     AG L+ A  +    VAEV      HR  VGL+     
Sbjct: 171 RHGEPARVAEGQDLLEAGGRH-GAGQLEGALAVAAEQVAEVEAAGGQHRP-VGLEGLALD 228

Query: 125 VAGTLALQ-------WLGPHA--HAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERG 175
             G +A++           H     GD     LR  G AA  +G  RG A   L  +   
Sbjct: 229 HDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSA 288

Query: 176 AV--GRAEDLQ-AGAGPRGAAEAQAPQLL---------GVGSAGLAAVVGDEAQALAAGS 223
           A   GR   L+ AG  PR      A   +         G G+      + DE+       
Sbjct: 289 AAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQ 348

Query: 224 QRPQGLGRARHGGLPAPQHAVAVE-QQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRP 282
              +GLG +   G    +   AV   +R H+ ++     G      G  A  +RR     
Sbjct: 349 SLAEGLGVSPQAGARVGEAREAVTTHERAHLDRE-----GEARARLGQAAAQMRREGWGA 403

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARR 342
            A    R +      G    P     P   AR  LA   A       G         ++ 
Sbjct: 404 RAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTG---------SQV 454

Query: 343 GERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCAR-GESSAGARPLFPGCRGPLTHWKR 401
           G RG  W P  GR            G +R +    R G  +A  RP             R
Sbjct: 455 GSRGRGWGPGAGRVPS---------GGRRGVGNPERWGGEAAAPRP------------SR 493

Query: 402 VVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTG 461
           V+      L  V  AR     P   A     L G   +G GAP SA+P P  R  +   G
Sbjct: 494 VLL---PELPAVDPARDTRREP-DAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPG 549

Query: 462 PPRGSLT 468
            P G  T
Sbjct: 550 EPPGPPT 556


>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
          Length = 962

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 65/232 (28%), Positives = 88/232 (37%), Gaps = 33/232 (14%)

Query: 235 GGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRR--HRRPPAA----AAR 288
           G  P P+     E +R    +     +G +P  A   +    +     RP AA    AA 
Sbjct: 455 GPAPEPEREAETEPERGAGTEPER--IGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512

Query: 289 RPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDH 348
            PL AA      P PG+L   A    RP A        PPAG   +AP    R+ ERG  
Sbjct: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKA---ERAEAPPAGAERAAP---ERKAERGGA 566

Query: 349 WLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGD- 407
            L    +        +P  GV R L      E ++G  PL     GP+  W+   +L D 
Sbjct: 567 ELRGAKKFSVSSCRARPRPGVSRPL------ERASGRLPL--ARSGPV--WRSEAALDDL 616

Query: 408 EALHGVTRARP-----AVHWPVSPAGMGGALAG---APREGAGAPSSAVPVP 451
           + L     A+P     A   P        + AG   +P+E A AP +  P P
Sbjct: 617 QGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/373 (26%), Positives = 116/373 (31%), Gaps = 68/373 (18%)

Query: 150 GQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLG-----VG 204
           G  +AAQ  G     AG A   V +G +G         GP G A A  PQ         G
Sbjct: 176 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGP----MGPRGPPGPAGAPGPQGFQGNPGEPG 231

Query: 205 SAGLAAVVGDEAQALAAGSQRPQGL----GRARHGGLPAPQHA------VAVEQQRVHVG 254
             G++  +G        G     G     G+A   G P PQ A        +   + H G
Sbjct: 232 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 291

Query: 255 QQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARR----------PLLAAARRG--ALPA 302
              L     +  A GV            P     R          P  AA  RG    P 
Sbjct: 292 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 351

Query: 303 PGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIG----EARRGERGDHWLPALGRPGD 358
           P    GP   A  P        P  P   G + P G    E  +G RG+   P  G PG 
Sbjct: 352 PAGPPGPVGPAGGP------GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP--GSPGP 403

Query: 359 WLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT---- 414
             A   P        +  A     AGA P FPG RGP         LG +   G      
Sbjct: 404 AGASGNPGTDGIPGAKGSAGAPGIAGA-PGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG 462

Query: 415 -RARPAVHWPVSPAGMGGALAGAPREG----AGAPSSAVPVPLCRGRARDTGPPRGSLTG 469
            +          PAG  GA   A  EG     G P    P+          GPP     G
Sbjct: 463 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI----------GPP-----G 507

Query: 470 QSREPARGSFPGR 482
           +   P    FPG+
Sbjct: 508 ERGAPGNRGFPGQ 520



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 92/326 (28%), Positives = 109/326 (33%), Gaps = 83/326 (25%)

Query: 163  GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQ-APQLLGV----GSAGLAAVVGDEAQ 217
            G  G A A  E+G VG         GP G+A A+ AP   G     G AG A   G + Q
Sbjct: 792  GPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 844

Query: 218  ALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRR 277
              A G Q   G  +    G P PQ                  P GA         TG   
Sbjct: 845  PGAKGEQGEAG--QKGDAGAPGPQG-----------------PSGAPGPQGPTGVTG--- 882

Query: 278  RHRRPPAAAARRPLLAAARRGALPAPGA--LIGPAPRARRPLACTFANPPPPPAGCGSSA 335
                 P  A          RGA   PGA    G A R   P +     PP PP   G   
Sbjct: 883  -----PKGA----------RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG 927

Query: 336  PIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGP 395
            P     +G RGD   P  GR G+   GLQ   G      K   G+         PG +G 
Sbjct: 928  P-----KGARGDSGPP--GRAGE--PGLQGPAGPPG--EKGEPGDDGPSGAEGPPGPQG- 975

Query: 396  LTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRG 455
                      G   + G+   R    +P    G+ G      ++GA   S        RG
Sbjct: 976  --------LAGQRGIVGLPGQRGERGFP----GLPGPSGEPGKQGAPGASGD------RG 1017

Query: 456  RARDTGPPRGSLTGQSREPARGSFPG 481
                 GPP   LTG + EP R   PG
Sbjct: 1018 PPGPVGPP--GLTGPAGEPGREGSPG 1041



 Score = 36.6 bits (83), Expect = 0.056
 Identities = 92/353 (26%), Positives = 111/353 (31%), Gaps = 58/353 (16%)

Query: 163 GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGV----GSAGLAAVVGDEAQA 218
           G AG   A  ERG  G A    A   P    E   P   G+    G AG    VG     
Sbjct: 522 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 581

Query: 219 LAAGSQRPQGLGRARHG----GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATG 274
              G   P G   AR      G P P+ A     +    G++ L      P A G+   G
Sbjct: 582 GEDGRPGPPGPQGARGQPGVMGFPGPKGA---NGEPGKAGEKGL------PGAPGL--RG 630

Query: 275 LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
           L  +     AA    P   A  RG   APG      P   + L      PP PP   G  
Sbjct: 631 LPGKDGETGAAGPPGPAGPAGERGEQGAPG------PSGFQGLP----GPPGPPGEGGKP 680

Query: 335 APIGEARR-------GERGDHWLPA-LGRPGDWLAGLQPAFGVKRSLRKCARGESSAGAR 386
              G           G RG+   P   G PG    GLQ   G+  +        +S  A 
Sbjct: 681 GDQGVPGEAGAPGLVGPRGERGFPGERGSPG--AQGLQGPRGLPGTPGTDGPKGASGPAG 738

Query: 387 PL----------FPGCRG------PLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMG 430
           P            PG RG      P      V   G E   G    R  +  P+ P G  
Sbjct: 739 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR-GLTGPIGPPGPA 797

Query: 431 GALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRR 483
           GA       G   P+ +       G   +TGPP     G +  P     PG +
Sbjct: 798 GANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGPPGADGQPGAK 848



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 80/300 (26%), Positives = 107/300 (35%), Gaps = 53/300 (17%)

Query: 188  GPRGA-------AEAQAPQLLG-VGSAGLAAVVGDEAQALAAGSQRPQGL-GRARHGGLP 238
            GP+GA         A  P L G  G  G     GD+  + A G   PQGL G+    GLP
Sbjct: 927  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 986

Query: 239  APQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLA-AARR 297
                      QR   G   L     +P   G          R PP       L   A   
Sbjct: 987  G---------QRGERGFPGLPGPSGEPGKQGAPGAS---GDRGPPGPVGPPGLTGPAGEP 1034

Query: 298  GALPAPGALIGPAPR---------ARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDH 348
            G   +PGA  GP  R              A      P PP   G + P G  ++G+RG+ 
Sbjct: 1035 GREGSPGA-DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTG--KQGDRGE- 1090

Query: 349  WLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGP--LTHWKRVVS-- 404
               A G  G   +G   A G++    +  RG+      P   G +G    T  + +    
Sbjct: 1091 -AGAQGPMGP--SGPAGARGIQGP--QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1145

Query: 405  --LGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGP 462
               GD+   G     PA   P  P G  G +  + ++GA      +  P  RGR+ +TGP
Sbjct: 1146 GPSGDQGASG-----PA--GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP 1198



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 84/343 (24%), Positives = 109/343 (31%), Gaps = 59/343 (17%)

Query: 174 RGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGL-GRA 232
           +G  G   D++   GP+G    Q P     G  G     GD+ +  A G +   G  G  
Sbjct: 103 KGQKGEPGDIKDIVGPKGPPGPQGP----AGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 158

Query: 233 RHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLL 292
            + G P P                   P G   + A  +A G   +         + P+ 
Sbjct: 159 GNPGPPGPPGPPG--------------PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 204

Query: 293 AAARRGALPAPGALIGPA-----------PRARRPLACTFANPPPPPAGCGSSAPIGE-A 340
               RG  P P    GP            P    P+      PP PP   G     G+  
Sbjct: 205 PMGPRGP-PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR--GPPGPPGKPGDDGEAGKPG 261

Query: 341 RRGERGDHW------------LPAL----GRPG-DWLAGLQPAFGVKRSLRKCARGESSA 383
           + GERG               LP +    G PG D   G   A GVK          S  
Sbjct: 262 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG 321

Query: 384 GARPL-FPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAP-REGA 441
              P   PG RG         + G++   G   A P    PV PAG G    GAP  +G 
Sbjct: 322 PMGPRGLPGERGRTGPAGAAGARGNDGQPGP--AGPP--GPVGPAG-GPGFPGAPGAKGE 376

Query: 442 GAPSSAVPVPLCRGRARDTGPPRG-SLTGQSREPARGSFPGRR 483
             P+ A      +G   + G P      G S  P     PG +
Sbjct: 377 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 419


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 97/373 (26%), Positives = 116/373 (31%), Gaps = 68/373 (18%)

Query: 150 GQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLG-----VG 204
           G  +AAQ  G     AG A   V +G +G         GP G A A  PQ         G
Sbjct: 107 GGNFAAQMAGGFDEKAGGAQLGVMQGPMGP----MGPRGPPGPAGAPGPQGFQGNPGEPG 162

Query: 205 SAGLAAVVGDEAQALAAGSQRPQGL----GRARHGGLPAPQHA------VAVEQQRVHVG 254
             G++  +G        G     G     G+A   G P PQ A        +   + H G
Sbjct: 163 EPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQGARGFPGTPGLPGVKGHRG 222

Query: 255 QQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARR----------PLLAAARRG--ALPA 302
              L     +  A GV            P     R          P  AA  RG    P 
Sbjct: 223 YPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGERGRTGPAGAAGARGNDGQPG 282

Query: 303 PGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIG----EARRGERGDHWLPALGRPGD 358
           P    GP   A  P        P  P   G + P G    E  +G RG+   P  G PG 
Sbjct: 283 PAGPPGPVGPAGGP------GFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTP--GSPGP 334

Query: 359 WLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT---- 414
             A   P        +  A     AGA P FPG RGP         LG +   G      
Sbjct: 335 AGASGNPGTDGIPGAKGSAGAPGIAGA-PGFPGPRGPPGPQGATGPLGPKGQTGEPGIAG 393

Query: 415 -RARPAVHWPVSPAGMGGALAGAPREG----AGAPSSAVPVPLCRGRARDTGPPRGSLTG 469
            +          PAG  GA   A  EG     G P    P+          GPP     G
Sbjct: 394 FKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI----------GPP-----G 438

Query: 470 QSREPARGSFPGR 482
           +   P    FPG+
Sbjct: 439 ERGAPGNRGFPGQ 451



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 92/326 (28%), Positives = 109/326 (33%), Gaps = 83/326 (25%)

Query: 163 GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQ-APQLLGV----GSAGLAAVVGDEAQ 217
           G  G A A  E+G VG         GP G+A A+ AP   G     G AG A   G + Q
Sbjct: 723 GPPGPAGANGEKGEVGPP-------GPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQ 775

Query: 218 ALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRR 277
             A G Q   G  +    G P PQ                  P GA         TG   
Sbjct: 776 PGAKGEQGEAG--QKGDAGAPGPQG-----------------PSGAPGPQGPTGVTG--- 813

Query: 278 RHRRPPAAAARRPLLAAARRGALPAPGA--LIGPAPRARRPLACTFANPPPPPAGCGSSA 335
                P  A          RGA   PGA    G A R   P +     PP PP   G   
Sbjct: 814 -----PKGA----------RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDG 858

Query: 336 PIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGP 395
           P     +G RGD   P  GR G+   GLQ   G      K   G+         PG +G 
Sbjct: 859 P-----KGARGDSGPP--GRAGE--PGLQGPAGPPG--EKGEPGDDGPSGAEGPPGPQG- 906

Query: 396 LTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRG 455
                     G   + G+   R    +P    G+ G      ++GA   S        RG
Sbjct: 907 --------LAGQRGIVGLPGQRGERGFP----GLPGPSGEPGKQGAPGASGD------RG 948

Query: 456 RARDTGPPRGSLTGQSREPARGSFPG 481
                GPP   LTG + EP R   PG
Sbjct: 949 PPGPVGPP--GLTGPAGEPGREGSPG 972



 Score = 36.6 bits (83), Expect = 0.056
 Identities = 92/353 (26%), Positives = 111/353 (31%), Gaps = 58/353 (16%)

Query: 163 GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGV----GSAGLAAVVGDEAQA 218
           G AG   A  ERG  G A    A   P    E   P   G+    G AG    VG     
Sbjct: 453 GLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAP 512

Query: 219 LAAGSQRPQGLGRARHG----GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATG 274
              G   P G   AR      G P P+ A     +    G++ L      P A G+   G
Sbjct: 513 GEDGRPGPPGPQGARGQPGVMGFPGPKGA---NGEPGKAGEKGL------PGAPGL--RG 561

Query: 275 LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
           L  +     AA    P   A  RG   APG      P   + L      PP PP   G  
Sbjct: 562 LPGKDGETGAAGPPGPAGPAGERGEQGAPG------PSGFQGLP----GPPGPPGEGGKP 611

Query: 335 APIGEARR-------GERGDHWLPA-LGRPGDWLAGLQPAFGVKRSLRKCARGESSAGAR 386
              G           G RG+   P   G PG    GLQ   G+  +        +S  A 
Sbjct: 612 GDQGVPGEAGAPGLVGPRGERGFPGERGSPG--AQGLQGPRGLPGTPGTDGPKGASGPAG 669

Query: 387 PL----------FPGCRG------PLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMG 430
           P            PG RG      P      V   G E   G    R  +  P+ P G  
Sbjct: 670 PPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGR-GLTGPIGPPGPA 728

Query: 431 GALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRR 483
           GA       G   P+ +       G   +TGPP     G +  P     PG +
Sbjct: 729 GANGEKGEVGPPGPAGSAGARGAPGERGETGPP--GPAGFAGPPGADGQPGAK 779



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 80/300 (26%), Positives = 107/300 (35%), Gaps = 53/300 (17%)

Query: 188  GPRGA-------AEAQAPQLLG-VGSAGLAAVVGDEAQALAAGSQRPQGL-GRARHGGLP 238
            GP+GA         A  P L G  G  G     GD+  + A G   PQGL G+    GLP
Sbjct: 858  GPKGARGDSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLP 917

Query: 239  APQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLA-AARR 297
                      QR   G   L     +P   G          R PP       L   A   
Sbjct: 918  G---------QRGERGFPGLPGPSGEPGKQGAPGAS---GDRGPPGPVGPPGLTGPAGEP 965

Query: 298  GALPAPGALIGPAPR---------ARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDH 348
            G   +PGA  GP  R              A      P PP   G + P G  ++G+RG+ 
Sbjct: 966  GREGSPGA-DGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTG--KQGDRGE- 1021

Query: 349  WLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGP--LTHWKRVVS-- 404
               A G  G   +G   A G++    +  RG+      P   G +G    T  + +    
Sbjct: 1022 -AGAQGPMGP--SGPAGARGIQGP--QGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPP 1076

Query: 405  --LGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGP 462
               GD+   G     PA   P  P G  G +  + ++GA      +  P  RGR+ +TGP
Sbjct: 1077 GPSGDQGASG-----PA--GPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGP 1129



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 84/343 (24%), Positives = 109/343 (31%), Gaps = 59/343 (17%)

Query: 174 RGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGL-GRA 232
           +G  G   D++   GP+G    Q P     G  G     GD+ +  A G +   G  G  
Sbjct: 34  KGQKGEPGDIKDIVGPKGPPGPQGP----AGEQGPRGDRGDKGEKGAPGPRGRDGEPGTP 89

Query: 233 RHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLL 292
            + G P P                   P G   + A  +A G   +         + P+ 
Sbjct: 90  GNPGPPGPPGPPG--------------PPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMG 135

Query: 293 AAARRGALPAPGALIGPA-----------PRARRPLACTFANPPPPPAGCGSSAPIGE-A 340
               RG  P P    GP            P    P+      PP PP   G     G+  
Sbjct: 136 PMGPRGP-PGPAGAPGPQGFQGNPGEPGEPGVSGPMGPR--GPPGPPGKPGDDGEAGKPG 192

Query: 341 RRGERGDHW------------LPAL----GRPG-DWLAGLQPAFGVKRSLRKCARGESSA 383
           + GERG               LP +    G PG D   G   A GVK          S  
Sbjct: 193 KAGERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPG 252

Query: 384 GARPL-FPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAP-REGA 441
              P   PG RG         + G++   G   A P    PV PAG G    GAP  +G 
Sbjct: 253 PMGPRGLPGERGRTGPAGAAGARGNDGQPGP--AGPP--GPVGPAG-GPGFPGAPGAKGE 307

Query: 442 GAPSSAVPVPLCRGRARDTGPPRG-SLTGQSREPARGSFPGRR 483
             P+ A      +G   + G P      G S  P     PG +
Sbjct: 308 AGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAK 350


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 93/334 (27%), Positives = 115/334 (34%), Gaps = 59/334 (17%)

Query: 135  GPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRAEDLQAGAGPRGAAE 194
            GP   AG   G   RG+   A   G   G  G      E+G+ G         GP GA  
Sbjct: 896  GPPGPAGKEGGKGPRGETGPAGRPG-EVGPPGPPGPAGEKGSPG-------ADGPAGAPG 947

Query: 195  AQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGL-GRARHGGLPAPQHAVAVEQQRVHV 253
               PQ    G AG   VVG   Q    G +   GL G +   G   P  A         +
Sbjct: 948  TPGPQ----GIAGQRGVVGLPGQR---GERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 254  GQQRLC-PLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGAL--IGPA 310
            G   L  P G         A G   R   P A   R     A   GA  APGA   +GPA
Sbjct: 1001 GPPGLAGPPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPA 1060

Query: 311  PRARRPLACTFANPPPPPAGCGSSAPIG-EARRGERGDHWLPALGRPGDWLAGLQPAFGV 369
             ++        A P  P    G+  P G +  RG++G+      G  GD         G+
Sbjct: 1061 GKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGE-----TGEQGDR--------GI 1107

Query: 370  KRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGM 429
            K       RG S     P  PG            S G++   G +        P  P G 
Sbjct: 1108 KGH-----RGFSGLQGPPGPPG------------SPGEQGPSGASG-------PAGPRGP 1143

Query: 430  GGALAGAP-REGAGAPSSAVPVPLCRGRARDTGP 462
             G+ AGAP ++G       +  P  RGR  D GP
Sbjct: 1144 PGS-AGAPGKDGLNGLPGPIGPPGPRGRTGDAGP 1176



 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 87/335 (25%), Positives = 114/335 (34%), Gaps = 57/335 (17%)

Query: 173  ERGAVGRA--EDLQAGAGPRGAAEAQAPQ----LLG-VGSAGLAAVVGDEAQALAAGSQR 225
            ERGA G    +  +  AGP+GA  +        L G +G  G A   GD+ ++  +G   
Sbjct: 732  ERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAG 791

Query: 226  PQGL-GRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGA--QPHAAGVVATGLRRRHRRP 282
            P G  G     G P P                   P GA  QP A G       +    P
Sbjct: 792  PTGARGAPGDRGEPGPPGPAGFAG-----------PPGADGQPGAKGEPGDAGAKGDAGP 840

Query: 283  PAAAARR----PLL------AAARRGALPAPGA--LIGPAPRARRPLACTFANPPPPPAG 330
            P  A       P+       A   RG+   PGA    G A R   P     A PP PP  
Sbjct: 841  PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP 900

Query: 331  CGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFP 390
             G     G+  RGE G    PA GRPG+    + P      +  K + G       P  P
Sbjct: 901  AGKEG--GKGPRGETG----PA-GRPGE----VGPPGPPGPAGEKGSPGADGPAGAPGTP 949

Query: 391  GCRGPLTHWKRVVSLGDEALHGVTRARPAVHWP--VSPAGMGGALAGAPREGAGAPSSAV 448
            G +G           G   + G+   R    +P    P+G  G    +   G   P   +
Sbjct: 950  GPQG---------IAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPM 1000

Query: 449  PVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRR 483
              P   G   ++G  R    G    P R   PG +
Sbjct: 1001 GPPGLAGPPGESG--REGAPGAEGSPGRDGSPGAK 1033



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 85/343 (24%), Positives = 111/343 (32%), Gaps = 57/343 (16%)

Query: 162 RGGAGQALAQVERGAVGRAEDLQAGAGPRGA-AEAQAPQLLGV-GSAGLAAVVGDEAQAL 219
           +G  G+A    E G  G A+ L    G  G   +   P   G  G  G     G   QA 
Sbjct: 520 KGSPGEAGRPGEAGLPG-AKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAG 578

Query: 220 AAGSQRPQGL----GRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGL 275
             G   P+G     G+A   G+P P  AV    +    G Q        P  AG      
Sbjct: 579 VMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQ------GPPGPAGPAG--- 629

Query: 276 RRRHRRPPAAAA--------RRPLLAAARRGALPAPGALIGPAPRARR-----PLACTFA 322
             R  + PA +           P   A + G    PG L  P P   R     P      
Sbjct: 630 -ERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQ 688

Query: 323 NPPPPPAGCGSS-APIGEARRGERGDHWLP-ALGRPGDWLAGLQPAFGVKRSLRKCARGE 380
            PP P    G++ AP  +  +G+ G    P + G PG  L G+               GE
Sbjct: 689 GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPG--LQGMP--------------GE 732

Query: 381 SSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREG 440
             A   P   G RG         S G + + G+T        P+ P G  GA       G
Sbjct: 733 RGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTG-------PIGPPGPAGAPGDKGESG 785

Query: 441 AGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRR 483
              P+         G   + GPP     G +  P     PG +
Sbjct: 786 PSGPAGPTGARGAPGDRGEPGPP--GPAGFAGPPGADGQPGAK 826



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 54/178 (30%), Positives = 59/178 (33%), Gaps = 22/178 (12%)

Query: 301 PAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEA----RRGERGDHW-LPALGR 355
           P P    GP      P A     P  PP   G +   GEA    R GERG      A G 
Sbjct: 196 PGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGL 255

Query: 356 PGDWLAGLQPAFGVKRSLRKCARGESSAG-----ARPLFPGCRGPLTHWKRVVSLGDEAL 410
           PG   AGL P     R        +  AG       P  PG  G          +G   L
Sbjct: 256 PG--TAGL-PGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENG------APGQMGPRGL 306

Query: 411 HGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGP--PRGS 466
            G  R RP    P    G  GA   A   G   P+     P   G   + GP  PRGS
Sbjct: 307 PG-ERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGS 363



 Score = 34.7 bits (78), Expect = 0.21
 Identities = 100/361 (27%), Positives = 116/361 (32%), Gaps = 74/361 (20%)

Query: 135 GPHAHAGDAHGLQLRGQGWAAQHVGLGRGGAGQALAQVERGAVGRA-EDLQAGA------ 187
           GP    G A  +   G   AA   G     AG+       GAVG A +D +AGA      
Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGK----AGERGVPGPPGAVGPAGKDGEAGAQGPPGP 624

Query: 188 -GPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAV 246
            GP G    Q P     GS G   + G       AG    QG+     G L AP  + A 
Sbjct: 625 AGPAGERGEQGP----AGSPGFQGLPGPAGPPGEAGKPGEQGVP----GDLGAPGPSGA- 675

Query: 247 EQQRVHVGQQRLC-------PLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGA 299
             +R   G++ +        P GA        A G       P +  A         RGA
Sbjct: 676 RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGA 735

Query: 300 LPAPGAL-----IGP-----APRARRPLACTFANPPPPPAGC----GSSAPIGEA----R 341
              PG        GP     +P        T    PP PAG     G S P G A     
Sbjct: 736 AGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGA 795

Query: 342 RGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKR 401
           RG  GD   P  G PG   AG     G        A G+  A   P   G +G       
Sbjct: 796 RGAPGDRGEP--GPPGP--AGFAGPPG--------ADGQPGAKGEPGDAGAKG------- 836

Query: 402 VVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTG 461
                D    G   A PA   P  P G  GA       G+  P  A   P   GR    G
Sbjct: 837 -----DAGPPGP--AGPA--GPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPG 887

Query: 462 P 462
           P
Sbjct: 888 P 888



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 52/185 (28%), Positives = 61/185 (32%), Gaps = 29/185 (15%)

Query: 163  GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQ-APQLLG----------VGSAGLAAV 211
            G  G   A+ +RG  G A       GP GA  A  AP  +G           G AG A  
Sbjct: 1025 GRDGSPGAKGDRGETGPA-------GPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGP 1077

Query: 212  VGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVV 271
            VG       AG Q P+G       G    Q    ++  R   G Q        P   G  
Sbjct: 1078 VGPVGARGPAGPQGPRG-----DKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPS 1132

Query: 272  ATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGC 331
                    R PP +A      A  + G    PG +  P PR R   A     PP PP   
Sbjct: 1133 GASGPAGPRGPPGSAG-----APGKDGLNGLPGPIGPPGPRGRTGDAGP-VGPPGPPGPP 1186

Query: 332  GSSAP 336
            G   P
Sbjct: 1187 GPPGP 1191



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 62/235 (26%), Positives = 74/235 (31%), Gaps = 60/235 (25%)

Query: 294 AARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIG-------EARRGERG 346
           A  RG   A GA   P P          A PP  P   G+    G       E  +G RG
Sbjct: 319 AGARGNDGATGAAGPPGPTGP-------AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRG 371

Query: 347 DHWLP----ALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRV 402
           +   P    A G  G+  A  QP         K A G       P FPG RGP       
Sbjct: 372 EPGPPGPAGAAGPAGNPGADGQPG-------AKGANGAPGIAGAPGFPGARGPSGPQGPG 424

Query: 403 VSLGDEALHGV-----------TRARP---AVHWPVSPAGMGG-----------ALAGAP 437
              G +   G             +  P    V  P  PAG  G            L G P
Sbjct: 425 GPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPP 484

Query: 438 REGAGAPSSAVP----VPLCRGRARDTGP-----PRGSLTGQSREPARGSFPGRR 483
            E  G  S   P    V   +G A + G      P+GS  G++  P     PG +
Sbjct: 485 GERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGS-PGEAGRPGEAGLPGAK 538


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 61/230 (26%), Positives = 82/230 (35%), Gaps = 30/230 (13%)

Query: 293 AAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAG---CGSSAPIGEARRGERGDHW 349
           AAAR  A  APG L    P + RP       PP  PA     G++  +G     ER    
Sbjct: 12  AAARTPAARAPGLLTPRPPGSPRP------PPPVTPAALRVLGAAGAVGRKPLAER---- 61

Query: 350 LPALGRPGDWLAGLQPAFGVKRSLRKCA--RGESSAGARPLFPG---CRGPLTHWKRVVS 404
             A G  G  +    P  G  R+ R  A  RGE +  A+   PG     G  +   R   
Sbjct: 62  --AGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGP 119

Query: 405 LGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRAR----DT 460
           LG + L  ++          + A    AL+   R     P+   P P    R+R    + 
Sbjct: 120 LGQKGLR-ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178

Query: 461 GPPRGSLTGQSREPARG-----SFPGRREYAPQSFAKTRSRFLGGNTNQP 505
           G PR + + + R P  G     S          S A  R    GG   +P
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRP 228


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 93/362 (25%), Positives = 122/362 (33%), Gaps = 48/362 (13%)

Query: 135  GPHAHAGDAHGLQLRGQGWAAQHVGL-GRGGA-GQALAQVERGAVGRAEDLQAGAGPRGA 192
            GP    G A     RG   +   +G  GR G  G   A  E+G  G    +    GP G 
Sbjct: 920  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI----GPTGR 975

Query: 193  AEAQAPQLLG--VGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQR 250
               Q P  L    G  G+A   GD+ +    G +  +G  +  HG    P     V Q  
Sbjct: 976  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG-NKGEHGPPGPPGPIGPVGQPG 1034

Query: 251  VHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPA 310
                       G Q H       G R  +  P     +     +  +G     G +  P 
Sbjct: 1035 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1094

Query: 311  PRARR-PLACTFANPPP-PPAGCGSSAPIGEARRGERGDHWLPAL-GRPGDWLAGLQPAF 367
            P   R P     A+ P  PP G G+  P GE  +GE G+   P + G PG  + G +   
Sbjct: 1095 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE--KGEPGESGSPGIQGEPG--VKGPRGER 1150

Query: 368  GVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT-----RARPAVHW 422
            G K        GES     P  PG +GP          GD+   G          P    
Sbjct: 1151 GEK--------GESGQPGEPGPPGPKGP---------TGDDGPKGNPGPVGFPGDPGPPG 1193

Query: 423  PVSPAGMGGALAGAPREG-AGAPSSAVPVPLCRGRARDTGP-----PRGSLTGQSREPAR 476
               P G  GA      +G  G P S  P     G     GP     P GS   + R+  +
Sbjct: 1194 EGGPRGQDGAKGDRGEDGEPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEGRQGGK 1249

Query: 477  GS 478
            G+
Sbjct: 1250 GA 1251



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 89/349 (25%), Positives = 111/349 (31%), Gaps = 71/349 (20%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAA 221
            RG +G++  + ERG  G     +   GPRGA      +    G++G     G   +    
Sbjct: 742  RGLSGKSGPRGERGPTGP----RGQRGPRGATGKSGAK----GTSGGDGPHGPPGERGLP 793

Query: 222  GSQRPQGL-GRARHGGLPAPQHAVAVEQQRVHVG-QQRLCPLG-----AQPHAAGVVATG 274
            G Q P G  G     G P          QR  VG Q +  P G         AAG     
Sbjct: 794  GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 853

Query: 275  LRRRHRRPPAAAARRPLLAAARR-------GALPAPGALIGPAPR----ARRPLACTFAN 323
              R H  PP     + L   A +       G   APG   GPA        R L  T   
Sbjct: 854  GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPAGLRGFPGERGLPGTAGG 912

Query: 324  P----------PPPPAG-------CGSSAPIGEARR-------GERGDHWLPA----LGR 355
            P          PP PAG        GS  PIG   R       G  G+  +P     +G 
Sbjct: 913  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972

Query: 356  PGDWLAGLQPAFGVKRSLRKCA-RGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT 414
             G    G+Q   G+          GE         PG +G         + G++  HG  
Sbjct: 973  TGR--DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG---------TKGNKGEHGP- 1020

Query: 415  RARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPP 463
               P    P+ P G  GA       GA  P          G     GPP
Sbjct: 1021 ---PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1066


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 93/362 (25%), Positives = 122/362 (33%), Gaps = 48/362 (13%)

Query: 135  GPHAHAGDAHGLQLRGQGWAAQHVGL-GRGGA-GQALAQVERGAVGRAEDLQAGAGPRGA 192
            GP    G A     RG   +   +G  GR G  G   A  E+G  G    +    GP G 
Sbjct: 899  GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI----GPTGR 954

Query: 193  AEAQAPQLLG--VGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQR 250
               Q P  L    G  G+A   GD+ +    G +  +G  +  HG    P     V Q  
Sbjct: 955  DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG-NKGEHGPPGPPGPIGPVGQPG 1013

Query: 251  VHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPA 310
                       G Q H       G R  +  P     +     +  +G     G +  P 
Sbjct: 1014 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1073

Query: 311  PRARR-PLACTFANPPP-PPAGCGSSAPIGEARRGERGDHWLPAL-GRPGDWLAGLQPAF 367
            P   R P     A+ P  PP G G+  P GE  +GE G+   P + G PG  + G +   
Sbjct: 1074 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE--KGEPGESGSPGIQGEPG--VKGPRGER 1129

Query: 368  GVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT-----RARPAVHW 422
            G K        GES     P  PG +GP          GD+   G          P    
Sbjct: 1130 GEK--------GESGQPGEPGPPGPKGP---------TGDDGPKGNPGPVGFPGDPGPPG 1172

Query: 423  PVSPAGMGGALAGAPREG-AGAPSSAVPVPLCRGRARDTGP-----PRGSLTGQSREPAR 476
               P G  GA      +G  G P S  P     G     GP     P GS   + R+  +
Sbjct: 1173 EGGPRGQDGAKGDRGEDGEPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEGRQGGK 1228

Query: 477  GS 478
            G+
Sbjct: 1229 GA 1230



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 89/349 (25%), Positives = 111/349 (31%), Gaps = 71/349 (20%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAA 221
            RG +G++  + ERG  G     +   GPRGA      +    G++G     G   +    
Sbjct: 721  RGLSGKSGPRGERGPTGP----RGQRGPRGATGKSGAK----GTSGGDGPHGPPGERGLP 772

Query: 222  GSQRPQGL-GRARHGGLPAPQHAVAVEQQRVHVG-QQRLCPLG-----AQPHAAGVVATG 274
            G Q P G  G     G P          QR  VG Q +  P G         AAG     
Sbjct: 773  GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 832

Query: 275  LRRRHRRPPAAAARRPLLAAARR-------GALPAPGALIGPAPR----ARRPLACTFAN 323
              R H  PP     + L   A +       G   APG   GPA        R L  T   
Sbjct: 833  GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPAGLRGFPGERGLPGTAGG 891

Query: 324  P----------PPPPAG-------CGSSAPIGEARR-------GERGDHWLPA----LGR 355
            P          PP PAG        GS  PIG   R       G  G+  +P     +G 
Sbjct: 892  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951

Query: 356  PGDWLAGLQPAFGVKRSLRKCA-RGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT 414
             G    G+Q   G+          GE         PG +G         + G++  HG  
Sbjct: 952  TGR--DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG---------TKGNKGEHGP- 999

Query: 415  RARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPP 463
               P    P+ P G  GA       GA  P          G     GPP
Sbjct: 1000 ---PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1045


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 93/362 (25%), Positives = 122/362 (33%), Gaps = 48/362 (13%)

Query: 135  GPHAHAGDAHGLQLRGQGWAAQHVGL-GRGGA-GQALAQVERGAVGRAEDLQAGAGPRGA 192
            GP    G A     RG   +   +G  GR G  G   A  E+G  G    +    GP G 
Sbjct: 1006 GPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPI----GPTGR 1061

Query: 193  AEAQAPQLLG--VGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQR 250
               Q P  L    G  G+A   GD+ +    G +  +G  +  HG    P     V Q  
Sbjct: 1062 DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKGTKG-NKGEHGPPGPPGPIGPVGQPG 1120

Query: 251  VHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPA 310
                       G Q H       G R  +  P     +     +  +G     G +  P 
Sbjct: 1121 AAGADGEPGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPG 1180

Query: 311  PRARR-PLACTFANPPP-PPAGCGSSAPIGEARRGERGDHWLPAL-GRPGDWLAGLQPAF 367
            P   R P     A+ P  PP G G+  P GE  +GE G+   P + G PG  + G +   
Sbjct: 1181 PPGPRGPAGPNGADGPQGPPGGVGNLGPPGE--KGEPGESGSPGIQGEPG--VKGPRGER 1236

Query: 368  GVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT-----RARPAVHW 422
            G K        GES     P  PG +GP          GD+   G          P    
Sbjct: 1237 GEK--------GESGQPGEPGPPGPKGP---------TGDDGPKGNPGPVGFPGDPGPPG 1279

Query: 423  PVSPAGMGGALAGAPREG-AGAPSSAVPVPLCRGRARDTGP-----PRGSLTGQSREPAR 476
               P G  GA      +G  G P S  P     G     GP     P GS   + R+  +
Sbjct: 1280 EGGPRGQDGAKGDRGEDGEPGQPGSPGPT----GENGPPGPLGKRGPAGSPGSEGRQGGK 1335

Query: 477  GS 478
            G+
Sbjct: 1336 GA 1337



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 89/349 (25%), Positives = 111/349 (31%), Gaps = 71/349 (20%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAA 221
            RG +G++  + ERG  G     +   GPRGA      +    G++G     G   +    
Sbjct: 828  RGLSGKSGPRGERGPTGP----RGQRGPRGATGKSGAK----GTSGGDGPHGPPGERGLP 879

Query: 222  GSQRPQGL-GRARHGGLPAPQHAVAVEQQRVHVG-QQRLCPLG-----AQPHAAGVVATG 274
            G Q P G  G     G P          QR  VG Q +  P G         AAG     
Sbjct: 880  GPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVGPQGAAGETGPM 939

Query: 275  LRRRHRRPPAAAARRPLLAAARR-------GALPAPGALIGPAPR----ARRPLACTFAN 323
              R H  PP     + L   A +       G   APG   GPA        R L  T   
Sbjct: 940  GERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGK-DGPAGLRGFPGERGLPGTAGG 998

Query: 324  P----------PPPPAG-------CGSSAPIGEARR-------GERGDHWLPA----LGR 355
            P          PP PAG        GS  PIG   R       G  G+  +P     +G 
Sbjct: 999  PGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058

Query: 356  PGDWLAGLQPAFGVKRSLRKCA-RGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVT 414
             G    G+Q   G+          GE         PG +G         + G++  HG  
Sbjct: 1059 TGR--DGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG---------TKGNKGEHGP- 1106

Query: 415  RARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPP 463
               P    P+ P G  GA       GA  P          G     GPP
Sbjct: 1107 ---PGPPGPIGPVGQPGAAGADGEPGARGPQGHFGAKGDEGTRGFNGPP 1152


>gi|13540521 basic helix-loop-helix domain containing, class B, 3
           [Homo sapiens]
          Length = 482

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 49/166 (29%), Positives = 66/166 (39%), Gaps = 24/166 (14%)

Query: 185 AGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAV 244
           +G GP G A A A  LLG   A  AA++  +A  L++      G      GG P PQ A 
Sbjct: 289 SGGGPGGGAAAAAAALLGPDPAAAAALLRPDAALLSSLVAFGGG------GGAPFPQPAA 342

Query: 245 AVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPG 304
           A       +    L P  A  +    +      ++  P AAAA  PLL       +PAP 
Sbjct: 343 AAAP--FCLPFCFLSPSAAAAYVQPFLDKSGLEKYLYPAAAAAPFPLLYP----GIPAPA 396

Query: 305 ALIGPAPRARR-----PLACTFANPPPPPAGCGSS-------APIG 338
           A    A  A       P   +  +PPP  AG  ++       AP+G
Sbjct: 397 AAAAAAAAAAAAAAAFPCLSSVLSPPPEKAGAAAATLLPHEVAPLG 442


>gi|239751352 PREDICTED: hypothetical protein XP_002347815 [Homo
           sapiens]
          Length = 697

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 64/206 (31%), Positives = 81/206 (39%), Gaps = 36/206 (17%)

Query: 152 GWAAQHVGLGRGGAGQALAQVERGAVGR---------AEDLQAGAGPRGAAEAQAPQLLG 202
           GW ++  G   GGAGQ + Q  RG  GR             QA A  RGAA  +A Q  G
Sbjct: 491 GWHSEAGGRRDGGAGQ-VVQGLRGPHGRRGPQVQAGWQAGRQAAALGRGAALRRAAQGAG 549

Query: 203 VGSAGLAAVVGDEAQALA----AGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRL 258
             S  L   VG   +  A       +R +G G AR G        VA   Q  HV ++++
Sbjct: 550 SASGLLGGAVGARGRRRAHKPVVVGERLRGRG-ARVGTWRRGGGRVAQRGQLAHVLRRQV 608

Query: 259 --CPLGAQPHAAGVVATGLRRRHR--RPPAAAARRPLLAAARRGAL----------PAPG 304
                G  PH   V+    ++     RP   AA  P+LA    G L          P PG
Sbjct: 609 EGAAAGLTPHVPPVLGAAPQQPVALIRPDGHAA--PVLAGVLEGVLHQHLHHRRREPEPG 666

Query: 305 ALIGPAPRARRPLACTFANPPPPPAG 330
               P+P    P  C+ A  PPP  G
Sbjct: 667 P---PSPARTAP--CSPALTPPPEKG 687


>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 122/482 (25%), Positives = 153/482 (31%), Gaps = 89/482 (18%)

Query: 81  VGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQRRVQPVAGTLALQWLGPHAHA 140
           +GA     GL  + +GL   H+       H  R            AG     WL      
Sbjct: 292 LGAAVGVRGLAGLQEGLDSRHLLHEAQPLHARRR-----------AGHAGSFWL-----R 335

Query: 141 GDAHGLQLRGQGWAAQHVGLGR---GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQA 197
           G    L+ RG G    H+G+     G  G+A    ERG  GR        G RG  +A  
Sbjct: 336 GGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGGRGRRRQ----QGRRGRRQA-G 389

Query: 198 PQLLGVGSAGLAAVVGDEAQALAA----GSQRPQGLGRARHGGLPAPQHAVAVEQQRVHV 253
           P L  V    LA  +G   Q +        Q  QG  R  H      Q A+     R H 
Sbjct: 390 PGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHG 449

Query: 254 GQQ-RLCPL-GAQPHAAGVVA---TGLRRR----HRRPPAAAARRPLLAAARRGALPAPG 304
            +  R+  L GA P  AG +A    GLR +       P   A    L+A    G     G
Sbjct: 450 RRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGV----G 505

Query: 305 ALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWLA--- 361
            L+G    A           P    GCG    +G   RG+R       +   G  LA   
Sbjct: 506 GLVGAGQGAVAAAGNAPERLPAGVQGCGEE--VGRGARGDRVAGGHVEVVPVGQQLAICM 563

Query: 362 -----GLQPAFGVKRSLRKCARGESSAGARPLFPGC----------RGPLTHWKRVVSLG 406
                G  P   V   L     G +   A P    C          R P          G
Sbjct: 564 LHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGG 623

Query: 407 DEAL------------HGVTRARPAVHWPVSPAGMGG----ALAGAPREGAGAPSSA--- 447
              L            HG     PA   P +  G  G         P+  AGAP  A   
Sbjct: 624 GPGLQDLLGGGHAGGAHGHVVVAPAAAAPTAREGRAGRHGHVAVVCPQVAAGAPVGADLD 683

Query: 448 VPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRREYAPQSFAKTRSRFLGGNTNQPLP 507
           V V L  G     G  RG+   ++   AR   P +  +          R  GG  ++PLP
Sbjct: 684 VSVVLWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFI--------QRGRGGLGHRPLP 735

Query: 508 GW 509
           GW
Sbjct: 736 GW 737



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 79/292 (27%), Positives = 100/292 (34%), Gaps = 56/292 (19%)

Query: 51  WAAISTARTRHPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAH 110
           W      R R  G  T+    V+   P    G   +AAG     Q  G       + +  
Sbjct: 333 WLRGGRDRLRRGGGHTKSHLGVVTIVP----GRRGRAAG----GQERGGRGRRRQQGRRG 384

Query: 111 HHRAHVGLQR-RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQH-VGLGRGGAGQA 168
             +A  GL +  V  +AG L L+W     HAG A G  L+GQ         L +     A
Sbjct: 385 RRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQA-GQPLQGQARGPHRPAALAQEALRAA 443

Query: 169 LAQVERGAVGRAEDLQAGAGPRGAAEAQAP----------------------QLLGVGSA 206
            A+       R   L+ GAGP GA     P                       L+ V + 
Sbjct: 444 AARPHGRRHYRVRGLR-GAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPAT 502

Query: 207 GLAAVVGDEAQALAAGSQRPQGL-----------GRARHGGLPAPQHAVAVEQQRVHVGQ 255
           G+  +VG    A+AA    P+ L           GR   G   A  H      + V VGQ
Sbjct: 503 GVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHV-----EVVPVGQ 557

Query: 256 Q-RLC----PLGAQPHA-AGVVATGLRRRHRRPPAAAARRPLLAAARRGALP 301
           Q  +C     LG  PHA    V  G         AA ARR   A  R G  P
Sbjct: 558 QLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWP 609



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 70/242 (28%), Positives = 85/242 (35%), Gaps = 42/242 (17%)

Query: 115 HVGLQRRVQPVAGTLALQWLGPHAHAGDAHGLQLRGQ----GWAAQHVGLGRGGAGQALA 170
           H+G  R         A +  GPH       G    G     GW  Q VG     + Q L 
Sbjct: 695 HLGRGRGAGRAEAARAAREGGPHQGVFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQVLG 754

Query: 171 QVERG-AVGRAEDLQA---GAGP---RGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGS 223
           +V R  AVG A   Q    G  P     AA       L  G   +A+V  + AQ   AG+
Sbjct: 755 RVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGAQVAWAGA 814

Query: 224 QRPQG-----LGRARHGGLPA--PQHAVAVE---QQRVHVGQQRL---CPLGAQPHAAGV 270
              QG      G AR GG  A  P     V+   Q+RV  G++R+       A    AG 
Sbjct: 815 VLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGA 874

Query: 271 VATGLRRRHRR------------------PPAAAARRPLLAAARRGALPAPGALIGPAPR 312
              G R RH                     PAAAA       A +G    PGA   P+ R
Sbjct: 875 GGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHR 934

Query: 313 AR 314
            R
Sbjct: 935 HR 936


>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 122/482 (25%), Positives = 153/482 (31%), Gaps = 89/482 (18%)

Query: 81  VGAHEQAAGLLQVAQGLGELHVAEVRVKAHHHRAHVGLQRRVQPVAGTLALQWLGPHAHA 140
           +GA     GL  + +GL   H+       H  R            AG     WL      
Sbjct: 292 LGAAVGVRGLAGLQEGLDSRHLLHEAQPLHARRR-----------AGHAGSFWL-----R 335

Query: 141 GDAHGLQLRGQGWAAQHVGLGR---GGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQA 197
           G    L+ RG G    H+G+     G  G+A    ERG  GR        G RG  +A  
Sbjct: 336 GGRDRLR-RGGGHTKSHLGVVTIVPGRRGRAAGGQERGGRGRRRQ----QGRRGRRQA-G 389

Query: 198 PQLLGVGSAGLAAVVGDEAQALAA----GSQRPQGLGRARHGGLPAPQHAVAVEQQRVHV 253
           P L  V    LA  +G   Q +        Q  QG  R  H      Q A+     R H 
Sbjct: 390 PGLAKVDVDVLAGALGLRWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHG 449

Query: 254 GQQ-RLCPL-GAQPHAAGVVA---TGLRRR----HRRPPAAAARRPLLAAARRGALPAPG 304
            +  R+  L GA P  AG +A    GLR +       P   A    L+A    G     G
Sbjct: 450 RRHYRVRGLRGAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGV----G 505

Query: 305 ALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWLA--- 361
            L+G    A           P    GCG    +G   RG+R       +   G  LA   
Sbjct: 506 GLVGAGQGAVAAAGNAPERLPAGVQGCGEE--VGRGARGDRVAGGHVEVVPVGQQLAICM 563

Query: 362 -----GLQPAFGVKRSLRKCARGESSAGARPLFPGC----------RGPLTHWKRVVSLG 406
                G  P   V   L     G +   A P    C          R P          G
Sbjct: 564 LHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGG 623

Query: 407 DEAL------------HGVTRARPAVHWPVSPAGMGG----ALAGAPREGAGAPSSA--- 447
              L            HG     PA   P +  G  G         P+  AGAP  A   
Sbjct: 624 GPGLQDLLGGGHAGGAHGHVVVAPAAAAPTAREGRAGRHGHVAVVCPQVAAGAPVGADLD 683

Query: 448 VPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGRREYAPQSFAKTRSRFLGGNTNQPLP 507
           V V L  G     G  RG+   ++   AR   P +  +          R  GG  ++PLP
Sbjct: 684 VSVVLWVGVVGHLGRGRGAGRAEAARAAREGGPHQGVFI--------QRGRGGLGHRPLP 735

Query: 508 GW 509
           GW
Sbjct: 736 GW 737



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 79/292 (27%), Positives = 100/292 (34%), Gaps = 56/292 (19%)

Query: 51  WAAISTARTRHPGARTRDEAAVLKRKPVVHVGAHEQAAGLLQVAQGLGELHVAEVRVKAH 110
           W      R R  G  T+    V+   P    G   +AAG     Q  G       + +  
Sbjct: 333 WLRGGRDRLRRGGGHTKSHLGVVTIVP----GRRGRAAG----GQERGGRGRRRQQGRRG 384

Query: 111 HHRAHVGLQR-RVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQH-VGLGRGGAGQA 168
             +A  GL +  V  +AG L L+W     HAG A G  L+GQ         L +     A
Sbjct: 385 RRQAGPGLAKVDVDVLAGALGLRWQWVLVHAGQA-GQPLQGQARGPHRPAALAQEALRAA 443

Query: 169 LAQVERGAVGRAEDLQAGAGPRGAAEAQAP----------------------QLLGVGSA 206
            A+       R   L+ GAGP GA     P                       L+ V + 
Sbjct: 444 AARPHGRRHYRVRGLR-GAGPEGAGRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPAT 502

Query: 207 GLAAVVGDEAQALAAGSQRPQGL-----------GRARHGGLPAPQHAVAVEQQRVHVGQ 255
           G+  +VG    A+AA    P+ L           GR   G   A  H      + V VGQ
Sbjct: 503 GVGGLVGAGQGAVAAAGNAPERLPAGVQGCGEEVGRGARGDRVAGGHV-----EVVPVGQ 557

Query: 256 Q-RLC----PLGAQPHA-AGVVATGLRRRHRRPPAAAARRPLLAAARRGALP 301
           Q  +C     LG  PHA    V  G         AA ARR   A  R G  P
Sbjct: 558 QLAICMLHGQLGTAPHAHVPTVLGGALGGRAGLVAAPARRECPARRRGGCWP 609



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 70/242 (28%), Positives = 85/242 (35%), Gaps = 42/242 (17%)

Query: 115 HVGLQRRVQPVAGTLALQWLGPHAHAGDAHGLQLRGQ----GWAAQHVGLGRGGAGQALA 170
           H+G  R         A +  GPH       G    G     GW  Q VG     + Q L 
Sbjct: 695 HLGRGRGAGRAEAARAAREGGPHQGVFIQRGRGGLGHRPLPGWRGQGVGPLAQPSVQVLG 754

Query: 171 QVERG-AVGRAEDLQA---GAGP---RGAAEAQAPQLLGVGSAGLAAVVGDEAQALAAGS 223
           +V R  AVG A   Q    G  P     AA       L  G   +A+V  + AQ   AG+
Sbjct: 755 RVPRDPAVGAATVAQGPVHGHVPVELTAAAAVSGRGRLRDGLGRVASVAAEGAQVAWAGA 814

Query: 224 QRPQG-----LGRARHGGLPA--PQHAVAVE---QQRVHVGQQRL---CPLGAQPHAAGV 270
              QG      G AR GG  A  P     V+   Q+RV  G++R+       A    AG 
Sbjct: 815 VLVQGHEAGVAGGARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGA 874

Query: 271 VATGLRRRHRR------------------PPAAAARRPLLAAARRGALPAPGALIGPAPR 312
              G R RH                     PAAAA       A +G    PGA   P+ R
Sbjct: 875 GGGGRRVRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHR 934

Query: 313 AR 314
            R
Sbjct: 935 HR 936


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 86/330 (26%), Positives = 105/330 (31%), Gaps = 80/330 (24%)

Query: 189 PRGAAEAQAPQLLGVGSAGLAAVVGDEAQA---------LAAGSQRPQGLG----RARHG 235
           PRG   ++ P+ LG  S     VVG  A            A GS  P+       RAR G
Sbjct: 154 PRGIYASERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSSAERRARAG 213

Query: 236 GL--PAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRP--- 290
               P+P HAVA+   R         P G  P  +             P A  A RP   
Sbjct: 214 PFLTPSPLHAVAMRSPR---------PCGRPPTDS-------------PDAGGAGRPLDG 251

Query: 291 ----LLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEARRGERG 346
               LL   RR     P    G A    R        PP      GS+ P  E       
Sbjct: 252 YISALLRRRRRRGAGQPRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPARE------- 304

Query: 347 DHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLG 406
               P+L R G       P      S    +  ES A   P  P             S  
Sbjct: 305 ----PSLERVGG-----HPTSPAALSRAWASSWESEAAPEPAAP---------PAAPSPP 346

Query: 407 DEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGS 466
           D    G  R   A + P    G   A  G P    G  +   P PL RGR+ +  PPR  
Sbjct: 347 DSPAEG--RLVKAQYIP----GAQAATRGLP----GRAARRKPPPLTRGRSVEQSPPRER 396

Query: 467 LTGQSREPARGSFPGRREYAPQSFAKTRSR 496
                R        GRR  +P++   +RS+
Sbjct: 397 PRAAGRRGRMAEASGRRG-SPRARKASRSQ 425


>gi|169217315 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 92/371 (24%), Positives = 133/371 (35%), Gaps = 71/371 (19%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGL-AAVVGDEAQALA 220
            R GA +A+A            ++    P   A       +G+G A    A+  D +QA  
Sbjct: 765  RSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDRSQAGR 824

Query: 221  AGSQRPQGLGR--ARHG-GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAG---VVATG 274
            A +  P  L R  +R G G+  P  A+  ++  V   ++ + P     H  G     ATG
Sbjct: 825  AIAPTPSALFRVGSRVGTGIALPAGALHRDRSPV---RRAVAPTPGTLHCDGSRKCTATG 881

Query: 275  LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
                   P A    R   +   +   PAPGAL     RARR +A      P P   CG  
Sbjct: 882  -----STPGALPGDR---SGVSKATAPAPGALCSERSRARRSIA------PTPCLLCGDR 927

Query: 335  APIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRG 394
            + +G           +     PG  L G           RKC     + GA       RG
Sbjct: 928  SWVG-----------MGIAPTPGALLGG---------KSRKCRAIAITPGA------LRG 961

Query: 395  PLTHWKRVVSLGDEALHG--------VTRARPAVHWPVSPAGMG-----GALAG-APREG 440
              +  +RVV+   EALHG        +     A+H   SPA        GAL G  P   
Sbjct: 962  GRSQKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTSIIPSPGALHGDGPPAH 1021

Query: 441  AGAPSSAVPVPLCRGRAR-DTGPPRGSLTGQS------REPARGSFPGRREYAPQSFAKT 493
               PS+   +      A     P  G++ G S        P+ G+  G R +  ++ A T
Sbjct: 1022 MAFPSTPGTLHGDASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWKRKAIAST 1081

Query: 494  RSRFLGGNTNQ 504
                 G  +++
Sbjct: 1082 PGALHGNRSDR 1092



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 66/271 (24%), Positives = 83/271 (30%), Gaps = 70/271 (25%)

Query: 259 CPLGAQPHAAGV----VATGLRRRHRRPPAAAARRP-----LLAAARRGALPAPGALIGP 309
           CPL       G+    +A  LRR       A A  P       + AR    P PG L G 
Sbjct: 597 CPLCEIWSRVGIGIAPIADALRRDRSPVRRAIAPTPGTLSGYRSRARTAIAPTPGTLRGY 656

Query: 310 APRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGV 369
            PR+RR +A T A                   RGE+          PG            
Sbjct: 657 RPRSRRAIASTPA-----------------TLRGEKSRAHTSLAPAPG------------ 687

Query: 370 KRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPA-- 427
                   RG+ S   R + P        W RV          + R RP V   ++P   
Sbjct: 688 ------ALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIAPTPG 741

Query: 428 --------------GMGGALAGAPREGAGAPSSAVPVPLC--RGRARDTGPP-------R 464
                            GAL  + R GA    +  P  LC  R R R    P       +
Sbjct: 742 ALRCDRSRELTAIDPTPGALC-SDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGK 800

Query: 465 GSLTGQSREPARGSFPGRREYAPQSFAKTRS 495
           GS  G    P  G+    R  A ++ A T S
Sbjct: 801 GSQVGMGVAPTPGALRRDRSQAGRAIAPTPS 831



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 62/248 (25%), Positives = 83/248 (33%), Gaps = 37/248 (14%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFAN-PPPPPAGCGSSAPIGEAR 341
           P   A R   +AAR   +P PGAL     RAR  +A T         + C + AP   A 
Sbjct: 414 PTPGALRGDRSAARTAFVPTPGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGAL 473

Query: 342 RGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLF---PGCRGPLTH 398
           RG +          PG W  G +   G   +    A G + + AR      PG       
Sbjct: 474 RGYKSWARRAIAPNPGAW-RGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRS 532

Query: 399 WKRVVSLGDEALHGVTRARPAVHWPVSPAGMGG-------ALAGAP----REGAGAPSSA 447
           W R             R+R       +PA + G       +LA  P     +G+ A  + 
Sbjct: 533 WTRRAIAPTPGTLSSYRSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRGDGSRARRAI 592

Query: 448 VPV--PLCR--------------GRARDTGPPRGSLTGQSREPARGSFPGRREYAPQSFA 491
           VP   PLC                  RD  P R ++      P  G+  G R  A  + A
Sbjct: 593 VPTTCPLCEIWSRVGIGIAPIADALRRDRSPVRRAIA-----PTPGTLSGYRSRARTAIA 647

Query: 492 KTRSRFLG 499
            T     G
Sbjct: 648 PTPGTLRG 655



 Score = 33.1 bits (74), Expect = 0.62
 Identities = 59/230 (25%), Positives = 78/230 (33%), Gaps = 35/230 (15%)

Query: 278 RHRRPPAAAARRPLLAAARRGA----LPAPGALIGPAPRARRPLACTFANPPPPPAGCGS 333
           R + P A A     L   R GA     P PGA++    RARR +                
Sbjct: 171 RSQEPTAIAPTPGALPGDRSGAPRAIAPTPGAMLSGRSRARRAI---------------- 214

Query: 334 SAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCR 393
            AP   A RG R          PG   +    A       R    G  S   R + P   
Sbjct: 215 -APTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPK-P 272

Query: 394 GPLTHWKRVVSLGDEALHGVTR-ARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPL 452
           G L   +   S   +   G  R  R   H  ++P    G+L G      GA  +  P  L
Sbjct: 273 GSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPT--PGSLCGNRSRACGA-IALTPGVL 329

Query: 453 CRGRAR---DTGPPRGSLTG------QSREPARGSFPGRREYAPQSFAKT 493
           C  R+R   D  P  G+L G      ++  P  G+  G R  A  +  +T
Sbjct: 330 CGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAARTAVVRT 379



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 61/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFA-----------NPPPPPAG- 330
           P   ARR   + A R   P PG+L G   RA   +A T             +  P P   
Sbjct: 288 PTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIALTPGVLCGVRSRVPKDITPTPGAL 347

Query: 331 -------CGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSA 383
                  C + AP   A RG+R       +  PG        A     S     +G  S+
Sbjct: 348 RGYKSWVCRAIAPTPGALRGDRSAARTAVVRTPGALGRDRSRARSAIASTPGTLQGNRSS 407

Query: 384 GARPLFP---GCRGPLTHWKRVVSLGDEALH-GVTRARPAVHWPVSPAGMGGALAGAPRE 439
            ++ + P     RG  +  +        ALH   +RAR A+    +P  + G  + A + 
Sbjct: 408 VSKAIAPTPGALRGDRSAARTAFVPTPGALHRDRSRARSAI--ASTPGTLRGNTSSACKA 465

Query: 440 GAGAPSS--AVPVPLCRGRARDTGPPRG--SLTGQSREPARGSFPGRREYAPQSFAKTRS 495
            A  P +         R  A + G  RG  S TG +  P  G+  G R  A    A T  
Sbjct: 466 IAPTPGALRGYKSWARRAIAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPG 525

Query: 496 RFLG 499
              G
Sbjct: 526 ALRG 529



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 51/183 (27%), Positives = 68/183 (37%), Gaps = 28/183 (15%)

Query: 276 RRRHRRPPAA--AARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCG- 332
           R R RR  A+  A  R   + A     P PGAL G   RARR +  T        +  G 
Sbjct: 549 RSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRGDGSRARRAIVPTTCPLCEIWSRVGI 608

Query: 333 SSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGC 392
             API +A R +R          PG  L+G               R  +     P     
Sbjct: 609 GIAPIADALRRDRSPVRRAIAPTPGT-LSGY--------------RSRARTAIAPTPGTL 653

Query: 393 RGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPV-- 450
           RG     +R ++     L G    +   H  ++PA   GAL G   +G+ A  + VP   
Sbjct: 654 RGYRPRSRRAIASTPATLRG---EKSRAHTSLAPA--PGALRG---DGSRARRAIVPTTC 705

Query: 451 PLC 453
           PLC
Sbjct: 706 PLC 708


>gi|113430659 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2061

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 92/371 (24%), Positives = 133/371 (35%), Gaps = 71/371 (19%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGL-AAVVGDEAQALA 220
            R GA +A+A            ++    P   A       +G+G A    A+  D +QA  
Sbjct: 765  RSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDRSQAGR 824

Query: 221  AGSQRPQGLGR--ARHG-GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAG---VVATG 274
            A +  P  L R  +R G G+  P  A+  ++  V   ++ + P     H  G     ATG
Sbjct: 825  AIAPTPSALFRVGSRVGTGIALPAGALHRDRSPV---RRAVAPTPGTLHCDGSRKCTATG 881

Query: 275  LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
                   P A    R   +   +   PAPGAL     RARR +A      P P   CG  
Sbjct: 882  -----STPGALPGDR---SGVSKATAPAPGALCSERSRARRSIA------PTPCLLCGDR 927

Query: 335  APIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRG 394
            + +G           +     PG  L G           RKC     + GA       RG
Sbjct: 928  SWVG-----------MGIAPTPGALLGG---------KSRKCRAIAITPGA------LRG 961

Query: 395  PLTHWKRVVSLGDEALHG--------VTRARPAVHWPVSPAGMG-----GALAG-APREG 440
              +  +RVV+   EALHG        +     A+H   SPA        GAL G  P   
Sbjct: 962  GRSQKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTSIIPSPGALHGDGPPAH 1021

Query: 441  AGAPSSAVPVPLCRGRAR-DTGPPRGSLTGQS------REPARGSFPGRREYAPQSFAKT 493
               PS+   +      A     P  G++ G S        P+ G+  G R +  ++ A T
Sbjct: 1022 MAFPSTPGTLHGDASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWKRKAIAST 1081

Query: 494  RSRFLGGNTNQ 504
                 G  +++
Sbjct: 1082 PGALHGNRSDR 1092



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 63/248 (25%), Positives = 84/248 (33%), Gaps = 37/248 (14%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFAN-PPPPPAGCGSSAPIGEAR 341
           PA  A R   +AAR   +P PGAL     RAR  +A T         + C + AP   A 
Sbjct: 414 PAPGALRGDRSAARTAFVPTPGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGAL 473

Query: 342 RGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLF---PGCRGPLTH 398
           RG +          PG W  G +   G   +    A G + + AR      PG       
Sbjct: 474 RGYKSWARRAIAPNPGAW-RGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRS 532

Query: 399 WKRVVSLGDEALHGVTRARPAVHWPVSPAGMGG-------ALAGAP----REGAGAPSSA 447
           W R             R+R       +PA + G       +LA  P     +G+ A  + 
Sbjct: 533 WTRRAIAPTPGTLSSYRSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRGDGSRARRAI 592

Query: 448 VPV--PLCR--------------GRARDTGPPRGSLTGQSREPARGSFPGRREYAPQSFA 491
           VP   PLC                  RD  P R ++      P  G+  G R  A  + A
Sbjct: 593 VPTTCPLCEIWSRVGIGIAPIADALRRDRSPVRRAIA-----PTPGTLSGYRSRARTAIA 647

Query: 492 KTRSRFLG 499
            T     G
Sbjct: 648 PTPGTLRG 655



 Score = 33.9 bits (76), Expect = 0.36
 Identities = 66/271 (24%), Positives = 83/271 (30%), Gaps = 70/271 (25%)

Query: 259 CPLGAQPHAAGV----VATGLRRRHRRPPAAAARRP-----LLAAARRGALPAPGALIGP 309
           CPL       G+    +A  LRR       A A  P       + AR    P PG L G 
Sbjct: 597 CPLCEIWSRVGIGIAPIADALRRDRSPVRRAIAPTPGTLSGYRSRARTAIAPTPGTLRGY 656

Query: 310 APRARRPLACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGV 369
            PR+RR +A T A                   RGE+          PG            
Sbjct: 657 RPRSRRAIASTPA-----------------TLRGEKSRAHTSLAPAPG------------ 687

Query: 370 KRSLRKCARGESSAGARPLFPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPA-- 427
                   RG+ S   R + P        W RV          + R RP V   ++P   
Sbjct: 688 ------ALRGDGSRARRAIVPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIAPTPG 741

Query: 428 --------------GMGGALAGAPREGAGAPSSAVPVPLC--RGRARDTGPP-------R 464
                            GAL  + R GA    +  P  LC  R R R    P       +
Sbjct: 742 ALRCDRSRELTAIDPTPGALC-SDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGK 800

Query: 465 GSLTGQSREPARGSFPGRREYAPQSFAKTRS 495
           GS  G    P  G+    R  A ++ A T S
Sbjct: 801 GSQVGMGVAPTPGALRRDRSQAGRAIAPTPS 831



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 59/230 (25%), Positives = 78/230 (33%), Gaps = 35/230 (15%)

Query: 278 RHRRPPAAAARRPLLAAARRGA----LPAPGALIGPAPRARRPLACTFANPPPPPAGCGS 333
           R + P A A     L   R GA     P PGA++    RARR +                
Sbjct: 171 RSQEPTAIAPTPGALPGDRSGAPRAIAPTPGAMLSGRSRARRAI---------------- 214

Query: 334 SAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCR 393
            AP   A RG R          PG   +    A       R    G  S   R + P   
Sbjct: 215 -APTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPK-P 272

Query: 394 GPLTHWKRVVSLGDEALHGVTR-ARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPL 452
           G L   +   S   +   G  R  R   H  ++P    G+L G      GA  +  P  L
Sbjct: 273 GSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPT--PGSLCGNRSRACGA-IALTPGVL 329

Query: 453 CRGRAR---DTGPPRGSLTG------QSREPARGSFPGRREYAPQSFAKT 493
           C  R+R   D  P  G+L G      ++  P  G+  G R  A  +  +T
Sbjct: 330 CGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRT 379



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 61/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFA-----------NPPPPPAG- 330
           P   ARR   + A R   P PG+L G   RA   +A T             +  P P   
Sbjct: 288 PTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIALTPGVLCGVRSRVPKDITPTPGAL 347

Query: 331 -------CGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSA 383
                  C + AP   A RG+R       +  PG        A     S     +G  S+
Sbjct: 348 RGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGALGRDRSRARSAIASTPGTLQGNRSS 407

Query: 384 GARPLFP---GCRGPLTHWKRVVSLGDEALH-GVTRARPAVHWPVSPAGMGGALAGAPRE 439
            ++ + P     RG  +  +        ALH   +RAR A+    +P  + G  + A + 
Sbjct: 408 VSKAIAPAPGALRGDRSAARTAFVPTPGALHRDRSRARSAI--ASTPGTLRGNTSSACKA 465

Query: 440 GAGAPSS--AVPVPLCRGRARDTGPPRG--SLTGQSREPARGSFPGRREYAPQSFAKTRS 495
            A  P +         R  A + G  RG  S TG +  P  G+  G R  A    A T  
Sbjct: 466 IAPTPGALRGYKSWARRAIAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPG 525

Query: 496 RFLG 499
              G
Sbjct: 526 ALRG 529



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 51/183 (27%), Positives = 68/183 (37%), Gaps = 28/183 (15%)

Query: 276 RRRHRRPPAA--AARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCG- 332
           R R RR  A+  A  R   + A     P PGAL G   RARR +  T        +  G 
Sbjct: 549 RSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRGDGSRARRAIVPTTCPLCEIWSRVGI 608

Query: 333 SSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGC 392
             API +A R +R          PG  L+G               R  +     P     
Sbjct: 609 GIAPIADALRRDRSPVRRAIAPTPGT-LSGY--------------RSRARTAIAPTPGTL 653

Query: 393 RGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPV-- 450
           RG     +R ++     L G    +   H  ++PA   GAL G   +G+ A  + VP   
Sbjct: 654 RGYRPRSRRAIASTPATLRG---EKSRAHTSLAPA--PGALRG---DGSRARRAIVPTTC 705

Query: 451 PLC 453
           PLC
Sbjct: 706 PLC 708



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 22/66 (33%), Positives = 24/66 (36%), Gaps = 5/66 (7%)

Query: 282  PPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEAR 341
            P A    R   +  R+   P PGA     PR  R  AC    P P   G  SS  I    
Sbjct: 1232 PGALLGNRSDRSRKRKAIAPTPGA-----PRIDRSPACRAIAPTPGALGDDSSTAIAPTP 1286

Query: 342  RGERGD 347
               RGD
Sbjct: 1287 GTPRGD 1292


>gi|113430177 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 2028

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 92/371 (24%), Positives = 133/371 (35%), Gaps = 71/371 (19%)

Query: 162  RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGL-AAVVGDEAQALA 220
            R GA +A+A            ++    P   A       +G+G A    A+  D +QA  
Sbjct: 733  RSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDRSQAGR 792

Query: 221  AGSQRPQGLGR--ARHG-GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAG---VVATG 274
            A +  P  L R  +R G G+  P  A+  ++  V   ++ + P     H  G     ATG
Sbjct: 793  AIAPTPSALFRVGSRVGTGIALPAGALHRDRSPV---RRAVAPTPGTLHCDGSRKCTATG 849

Query: 275  LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
                   P A    R   +   +   PAPGAL     RARR +A      P P   CG  
Sbjct: 850  -----STPGALPGDR---SGVSKATAPAPGALCSERSRARRSIA------PTPCLLCGDR 895

Query: 335  APIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRG 394
            + +G           +     PG  L G           RKC     + GA       RG
Sbjct: 896  SWVG-----------MGIAPTPGALLGG---------KSRKCRAIAITPGA------LRG 929

Query: 395  PLTHWKRVVSLGDEALHG--------VTRARPAVHWPVSPAGMG-----GALAG-APREG 440
              +  +RVV+   EALHG        +     A+H   SPA        GAL G  P   
Sbjct: 930  GRSQKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTSIIPSPGALHGDGPPAH 989

Query: 441  AGAPSSAVPVPLCRGRAR-DTGPPRGSLTGQS------REPARGSFPGRREYAPQSFAKT 493
               PS+   +      A     P  G++ G S        P+ G+  G R +  ++ A T
Sbjct: 990  MAFPSTPGTLHGDASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWKRKAIAST 1049

Query: 494  RSRFLGGNTNQ 504
                 G  +++
Sbjct: 1050 PGALHGNRSDR 1060



 Score = 38.9 bits (89), Expect = 0.011
 Identities = 59/223 (26%), Positives = 78/223 (34%), Gaps = 19/223 (8%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFAN-PPPPPAGCGSSAPIGEAR 341
           PA  A R   +AAR   +P PGAL     RAR  +A T         + C + AP   A 
Sbjct: 414 PAPGALRGDRSAARTAFVPTPGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGAL 473

Query: 342 RGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLF---PGCRGPLTH 398
           RG +          PG W  G +   G   +    A G + + AR      PG       
Sbjct: 474 RGYKSWARRAIAPNPGAW-RGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRS 532

Query: 399 WKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVP--LCRGR 456
           W R             R+R       +PA + G       E + A +S  P P  L    
Sbjct: 533 WTRRAIAPTPGTLSSYRSRSRRTIASTPATLRG-------EKSRAHTSLAPTPGALRDAL 585

Query: 457 ARDTGPPRGSLTGQSREPARGSFPGRREYAPQSFAKTRSRFLG 499
            RD  P R ++      P  G+  G R  A  + A T     G
Sbjct: 586 RRDRSPVRRAIA-----PTPGTLSGYRSRARTAIAPTPGTLRG 623



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 59/230 (25%), Positives = 78/230 (33%), Gaps = 35/230 (15%)

Query: 278 RHRRPPAAAARRPLLAAARRGA----LPAPGALIGPAPRARRPLACTFANPPPPPAGCGS 333
           R + P A A     L   R GA     P PGA++    RARR +                
Sbjct: 171 RSQEPTAIAPTPGALPGDRSGAPRAIAPTPGAMLSGRSRARRAI---------------- 214

Query: 334 SAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCR 393
            AP   A RG R          PG   +    A       R    G  S   R + P   
Sbjct: 215 -APTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPK-P 272

Query: 394 GPLTHWKRVVSLGDEALHGVTR-ARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPL 452
           G L   +   S   +   G  R  R   H  ++P    G+L G      GA  +  P  L
Sbjct: 273 GSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPT--PGSLCGNRSRACGA-IALTPGVL 329

Query: 453 CRGRAR---DTGPPRGSLTG------QSREPARGSFPGRREYAPQSFAKT 493
           C  R+R   D  P  G+L G      ++  P  G+  G R  A  +  +T
Sbjct: 330 CGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRT 379



 Score = 32.7 bits (73), Expect = 0.81
 Identities = 63/252 (25%), Positives = 78/252 (30%), Gaps = 33/252 (13%)

Query: 276 RRRHRRPPAA--AARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGS 333
           R R RR  A+  A  R   + A     P PGAL     R R P+    A  P   +G  S
Sbjct: 549 RSRSRRTIASTPATLRGEKSRAHTSLAPTPGALRDALRRDRSPVRRAIAPTPGTLSGYRS 608

Query: 334 S-----APIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPL 388
                 AP     RG R          P         A           RG+ S   R +
Sbjct: 609 RARTAIAPTPGTLRGYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRGDGSRARRAI 668

Query: 389 FPGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPA----------------GMGGA 432
            P        W RV          + R RP V   ++P                    GA
Sbjct: 669 VPTTCPLCEIWSRVGIGIAPIADALRRDRPPVRRAIAPTPGALRCDRSRELTAIDPTPGA 728

Query: 433 LAGAPREGAGAPSSAVPVPLC--RGRARDTGPP-------RGSLTGQSREPARGSFPGRR 483
           L  + R GA    +  P  LC  R R R    P       +GS  G    P  G+    R
Sbjct: 729 LC-SDRSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDR 787

Query: 484 EYAPQSFAKTRS 495
             A ++ A T S
Sbjct: 788 SQAGRAIAPTPS 799



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 61/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFA-----------NPPPPPAG- 330
           P   ARR   + A R   P PG+L G   RA   +A T             +  P P   
Sbjct: 288 PTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIALTPGVLCGVRSRVPKDITPTPGAL 347

Query: 331 -------CGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSA 383
                  C + AP   A RG+R       +  PG        A     S     +G  S+
Sbjct: 348 RGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGALGRDRSRARSAIASTPGTLQGNRSS 407

Query: 384 GARPLFP---GCRGPLTHWKRVVSLGDEALH-GVTRARPAVHWPVSPAGMGGALAGAPRE 439
            ++ + P     RG  +  +        ALH   +RAR A+    +P  + G  + A + 
Sbjct: 408 VSKAIAPAPGALRGDRSAARTAFVPTPGALHRDRSRARSAI--ASTPGTLRGNTSSACKA 465

Query: 440 GAGAPSS--AVPVPLCRGRARDTGPPRG--SLTGQSREPARGSFPGRREYAPQSFAKTRS 495
            A  P +         R  A + G  RG  S TG +  P  G+  G R  A    A T  
Sbjct: 466 IAPTPGALRGYKSWARRAIAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPG 525

Query: 496 RFLG 499
              G
Sbjct: 526 ALRG 529



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 274 GLRRRHRRPPAA--AARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGC 331
           G R R RR  A+  A  R   + A     PAPGAL G   RARR +  T        +  
Sbjct: 623 GYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRV 682

Query: 332 G-SSAPIGEARRGER 345
           G   API +A R +R
Sbjct: 683 GIGIAPIADALRRDR 697



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 22/66 (33%), Positives = 24/66 (36%), Gaps = 5/66 (7%)

Query: 282  PPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEAR 341
            P A    R   +  R+   P PGA     PR  R  AC    P P   G  SS  I    
Sbjct: 1200 PGALLGNRSDRSRKRKAIAPTPGA-----PRIDRSPACRAIAPTPGALGDDSSTAIAPTP 1254

Query: 342  RGERGD 347
               RGD
Sbjct: 1255 GTPRGD 1260


>gi|113430175 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1934

 Score = 42.7 bits (99), Expect = 8e-04
 Identities = 92/371 (24%), Positives = 133/371 (35%), Gaps = 71/371 (19%)

Query: 162 RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGL-AAVVGDEAQALA 220
           R GA +A+A            ++    P   A       +G+G A    A+  D +QA  
Sbjct: 639 RSGASRAIAPTPGTLCSERSRVRRAIAPTPCALCGKGSQVGMGVAPTPGALRRDRSQAGR 698

Query: 221 AGSQRPQGLGR--ARHG-GLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAG---VVATG 274
           A +  P  L R  +R G G+  P  A+  ++  V   ++ + P     H  G     ATG
Sbjct: 699 AIAPTPSALFRVGSRVGTGIALPAGALHRDRSPV---RRAVAPTPGTLHCDGSRKCTATG 755

Query: 275 LRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSS 334
                  P A    R   +   +   PAPGAL     RARR +A      P P   CG  
Sbjct: 756 -----STPGALPGDR---SGVSKATAPAPGALCSERSRARRSIA------PTPCLLCGDR 801

Query: 335 APIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCRG 394
           + +G           +     PG  L G           RKC     + GA       RG
Sbjct: 802 SWVG-----------MGIAPTPGALLGG---------KSRKCRAIAITPGA------LRG 835

Query: 395 PLTHWKRVVSLGDEALHG--------VTRARPAVHWPVSPAGMG-----GALAG-APREG 440
             +  +RVV+   EALHG        +     A+H   SPA        GAL G  P   
Sbjct: 836 GRSQKRRVVAPTPEALHGDGSWTYMAIAPTPGALHGDSSPAHTSIIPSPGALHGDGPPAH 895

Query: 441 AGAPSSAVPVPLCRGRAR-DTGPPRGSLTGQS------REPARGSFPGRREYAPQSFAKT 493
              PS+   +      A     P  G++ G S        P+ G+  G R +  ++ A T
Sbjct: 896 MAFPSTPGTLHGDASHAHMAIAPTPGTMRGDSSTARTATAPSPGALRGDRSWKRKAIAST 955

Query: 494 RSRFLGGNTNQ 504
                G  +++
Sbjct: 956 PGALHGNRSDR 966



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 52/178 (29%), Positives = 71/178 (39%), Gaps = 16/178 (8%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFAN-PPPPPAGCGSSAPIGEAR 341
           PA  A R   +AAR   +P PGAL     RAR  +A T         + C + AP   A 
Sbjct: 414 PAPGALRGDRSAARTAFVPTPGALHRDRSRARSAIASTPGTLRGNTSSACKAIAPTPGAL 473

Query: 342 RGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGAR----PLFPGCRGPLT 397
           RG +          PG W  G +   G   +    A G + + AR    P     RG   
Sbjct: 474 RGYKSWARRAIAPNPGAW-RGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPGALRGYRP 532

Query: 398 HWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPV--PLC 453
             +R ++     L G    +   H  ++PA   GAL G   +G+ A  + VP   PLC
Sbjct: 533 RSRRAIASTPATLRG---EKSRAHTSLAPA--PGALRG---DGSRARRAIVPTTCPLC 582



 Score = 33.5 bits (75), Expect = 0.48
 Identities = 59/230 (25%), Positives = 78/230 (33%), Gaps = 35/230 (15%)

Query: 278 RHRRPPAAAARRPLLAAARRGA----LPAPGALIGPAPRARRPLACTFANPPPPPAGCGS 333
           R + P A A     L   R GA     P PGA++    RARR +                
Sbjct: 171 RSQEPTAIAPTPGALPGDRSGAPRAIAPTPGAMLSGRSRARRAI---------------- 214

Query: 334 SAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAGARPLFPGCR 393
            AP   A RG R          PG   +    A       R    G  S   R + P   
Sbjct: 215 -APTPSALRGYRSWAHRAIAPTPGCLYSDRSRAHRAIAPARGTKHGGRSWACRSIAPK-P 272

Query: 394 GPLTHWKRVVSLGDEALHGVTR-ARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVPVPL 452
           G L   +   S   +   G  R  R   H  ++P    G+L G      GA  +  P  L
Sbjct: 273 GSLCGDRSQASRAIDPTLGARRGGRSRAHRAIAPT--PGSLCGNRSRACGA-IALTPGVL 329

Query: 453 CRGRAR---DTGPPRGSLTG------QSREPARGSFPGRREYAPQSFAKT 493
           C  R+R   D  P  G+L G      ++  P  G+  G R  A  +  +T
Sbjct: 330 CGVRSRVPKDITPTPGALRGYKSWVCRAIAPTPGALRGDRSAARTAIVRT 379



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 61/244 (25%), Positives = 85/244 (34%), Gaps = 29/244 (11%)

Query: 283 PAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFA-----------NPPPPPAG- 330
           P   ARR   + A R   P PG+L G   RA   +A T             +  P P   
Sbjct: 288 PTLGARRGGRSRAHRAIAPTPGSLCGNRSRACGAIALTPGVLCGVRSRVPKDITPTPGAL 347

Query: 331 -------CGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSA 383
                  C + AP   A RG+R       +  PG        A     S     +G  S+
Sbjct: 348 RGYKSWVCRAIAPTPGALRGDRSAARTAIVRTPGALGRDRSRARSAIASTPGTLQGNRSS 407

Query: 384 GARPLFP---GCRGPLTHWKRVVSLGDEALH-GVTRARPAVHWPVSPAGMGGALAGAPRE 439
            ++ + P     RG  +  +        ALH   +RAR A+    +P  + G  + A + 
Sbjct: 408 VSKAIAPAPGALRGDRSAARTAFVPTPGALHRDRSRARSAI--ASTPGTLRGNTSSACKA 465

Query: 440 GAGAPSS--AVPVPLCRGRARDTGPPRG--SLTGQSREPARGSFPGRREYAPQSFAKTRS 495
            A  P +         R  A + G  RG  S TG +  P  G+  G R  A    A T  
Sbjct: 466 IAPTPGALRGYKSWARRAIAPNPGAWRGYRSTTGTAIAPNLGALGGNRSAARTDIAPTPG 525

Query: 496 RFLG 499
              G
Sbjct: 526 ALRG 529



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 28/75 (37%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 274 GLRRRHRRPPAA--AARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGC 331
           G R R RR  A+  A  R   + A     PAPGAL G   RARR +  T        +  
Sbjct: 529 GYRPRSRRAIASTPATLRGEKSRAHTSLAPAPGALRGDGSRARRAIVPTTCPLCEIWSRV 588

Query: 332 G-SSAPIGEARRGER 345
           G   API +A R +R
Sbjct: 589 GIGIAPIADALRRDR 603



 Score = 29.6 bits (65), Expect = 6.9
 Identities = 22/66 (33%), Positives = 24/66 (36%), Gaps = 5/66 (7%)

Query: 282  PPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPIGEAR 341
            P A    R   +  R+   P PGA     PR  R  AC    P P   G  SS  I    
Sbjct: 1106 PGALLGNRSDRSRKRKAIAPTPGA-----PRIDRSPACRAIAPTPGALGDDSSTAIAPTP 1160

Query: 342  RGERGD 347
               RGD
Sbjct: 1161 GTPRGD 1166


>gi|30179900 SRY (sex determining region Y)-box 1 [Homo sapiens]
          Length = 391

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 96/323 (29%), Positives = 120/323 (37%), Gaps = 68/323 (21%)

Query: 106 RVKAHHHRAHVGLQRRVQPVAGTLALQWLGPHAHAGDAHGLQLRGQGWAAQHVGLGRG-G 164
           R++A H + H   + R  P   T  L     ++ AG   GL   G G     V +G G G
Sbjct: 106 RLRALHMKEHPDYKYR--PRRKTKTLLKKDKYSLAG---GLLAAGAGGGGAAVAMGVGVG 160

Query: 165 AGQALAQVERGAVGRAEDLQAGAGPRGAAE----AQAPQLLGVGSAGLAAVVGDEAQALA 220
            G A       AVG+  +   GA   G A     A       V +A  AA +  EAQ LA
Sbjct: 161 VGAA-------AVGQRLESPGGAAGGGYAHVNGWANGAYPGSVAAAAAAAAMMQEAQ-LA 212

Query: 221 AGSQRPQGLGRAR---HGGLPAPQHAVA-----VEQQRVHVGQQRLCPL----------- 261
            G Q P G G A    H   P P H  A         R  +G  +  P+           
Sbjct: 213 YG-QHP-GAGGAHPHAHPAHPHPHHPHAHPHNPQPMHRYDMGALQYSPISNSQGYMSASP 270

Query: 262 ---GAQPH-AAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPL 317
              G  P+ AA   A      H+    AAA     AAA  GAL A G+L+   P      
Sbjct: 271 SGYGGLPYGAAAAAAAAAGGAHQNSAVAAAAAA--AAASSGALGALGSLVKSEP------ 322

Query: 318 ACTFANPPPPPAGCGSSAPIGEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCA 377
               +  PP PA   +  P G+ R  E    +LPA G  GD  A    A   +  L    
Sbjct: 323 ----SGSPPAPAHSRAPCP-GDLR--EMISMYLPA-GEGGDPAAA--AAAAAQSRLHSLP 372

Query: 378 RGESSAGARPLFPGCRG--PLTH 398
           +    AGA     G  G  PLTH
Sbjct: 373 QHYQGAGA-----GVNGTVPLTH 390


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 58/209 (27%), Positives = 73/209 (34%), Gaps = 24/209 (11%)

Query: 146 LQLRGQGWAAQHVGLGRGGA--GQALAQVERGAVGRAEDLQAGAGP-----RGAA---EA 195
           LQ +G  W  Q   LG  GA  G +   V   A   +++     GP     R AA    A
Sbjct: 30  LQRKGLFWRYQKT-LGPAGARRGHSPPTVAPAASAGSQEHPGAGGPLCFPARSAAWGPPA 88

Query: 196 QAPQLLG--VGSAGLAAVVGDEAQALAAGSQRPQGLGRARHGGLPAPQHAVAVEQQRVHV 253
           +A +  G   G AG         +A A       G  R    G+     A A        
Sbjct: 89  RASRAAGRRAGPAGPPCRAPGRGRAAATRRSPAPGTARGSPAGVERAGGATAASSAGTRS 148

Query: 254 GQQRLCPLGAQPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAP-- 311
              R  P    P   G       R  RRP +AA  R   ++ R  A+P PGA    AP  
Sbjct: 149 VPARRLP----PPCGGTSLGAGSRALRRPGSAALPRSPSSSRRWAAMPGPGAPRPGAPGT 204

Query: 312 -----RARRPLACTFANPPPPPAGCGSSA 335
                    P A   +  PPPPA  G+ A
Sbjct: 205 WPVGFAVAAPPAAAASVAPPPPAVAGAPA 233


>gi|239751471 PREDICTED: hypothetical protein XP_002347846 [Homo
           sapiens]
          Length = 870

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 100/357 (28%), Positives = 123/357 (34%), Gaps = 40/357 (11%)

Query: 162 RGGAGQALAQVERGA-----VGRAEDLQAGAG-PRGAAEAQAPQLLGVGSAGLAAVVGDE 215
           RGG G+A A++ RG      VG       GA  P G  E +A   L V  AG   +    
Sbjct: 489 RGGTGRAPARLRRGRGMPGRVGNGVGEGRGASEPEGEPEPRARADLEVLQAGFERLQSLP 548

Query: 216 AQALAAGSQRPQGLGRARHGGLP-APQHAVAVEQQRVHVGQQRLCPLGAQPHAAG---VV 271
             A   G + P   G+  HG L  A   A A        G QR   L A         VV
Sbjct: 549 ELAERLGGRCP---GQVAHGVLARAGLLAAAARPGLAGSGVQRALALAAAQLGGWTTCVV 605

Query: 272 ATGLRRRHRRPPAAAARRPLLAAARRGALPAPG-ALIGPAPRARRPLACTFANPPPPPAG 330
           +  LRR  RR      R     +A   AL   G    G    A+ P + T   P    + 
Sbjct: 606 SPNLRRGSRRAGNHRVREIEFGSALLAALNTLGPGSFGAGLGAQGPRSSTPECPVVNGSE 665

Query: 331 CGSSAPIGEARRGERGDHWLPALGR-PGDWLAGLQPAFGVKRSLRKCARGESSAGARPLF 389
            G +AP+      ERG    PA  R PG  L G  P  G       C RG        L 
Sbjct: 666 WGLAAPLSP----ERGSPGRPAFLRSPG--LCGPGPVPGGLSVPTPCGRGAGDFSEADLA 719

Query: 390 PGCRGPLTHWKRVVSLGDEALHGVTRARPAVHWPVSPAGMGGALAGAPREGAGAPSSAVP 449
                     +     G   + G  R R    W  + A       GAPRE   A  +A P
Sbjct: 720 D---------RAFPVRGAGPIAGRRRRRG---WTFAAA----LRKGAPREQPPASPAASP 763

Query: 450 VPLCRGRARDTGPP--RGSLTGQSREPARGSFPGRREYAPQSFAKTRSRFLGGNTNQ 504
               R   ++T  P  RG  T  +  P   + PG            RSR LG  + Q
Sbjct: 764 CQAPRAPEKETEAPRLRGRATAVAPRPLPAA-PGFSGLCVLQPFPARSRGLGVPSQQ 819


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 37/88 (42%), Positives = 40/88 (45%), Gaps = 9/88 (10%)

Query: 260 PLGAQPHAAGVVATGLRRRHRRPPA-----AAARRPLLAAARRGALPAPGALIGPAPRAR 314
           P GA P AA   A         PPA     A AR P  AAA   A P+PG    P PRA+
Sbjct: 115 PRGA-PAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAPPSPGPA-QPGPRAQ 172

Query: 315 RPLACTFANPPPPPAGCGSSAPIGEARR 342
           R  A   A PPP PA   + AP    RR
Sbjct: 173 R--AAPLAAPPPAPAAPPAVAPPAGPRR 198



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 57/232 (24%), Positives = 72/232 (31%), Gaps = 45/232 (19%)

Query: 281 RPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPPAGCGSSAPI--- 337
           +PP   A  P    A RGA PA  A   P P            PPPPPA   ++AP    
Sbjct: 100 QPPRRGATPPAPPRAPRGA-PAAAAAAAPPPTPA---------PPPPPAPVAAAAPARAP 149

Query: 338 -------------GEARRGERGDHWLPALGRPGDWLAGLQPAFGVKRSLRKCARGESSAG 384
                        G A+ G R     P    P        PA       R+      +A 
Sbjct: 150 RAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPP--APAAPPAVAPPAGPRRAPPPAVAAR 207

Query: 385 ARPLFPGCRGPLTHWKR--------------VVSLGDEALHGVTRARPAVHWPVSPAGMG 430
             PL P  + P    ++               V  G  A       R  V +     G G
Sbjct: 208 EPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAA--RPVSLREVVRYLGGSGGAG 265

Query: 431 GALAGAPREGAGAPSSAVPVPLCRGRARDTGPPRGSLTGQSREPARGSFPGR 482
           G L     +G     +A    L R R      PRG   G++  PA  + P R
Sbjct: 266 GRLTRGRVQGLLEEEAAARGRLERTRLGALALPRGDRPGRA-PPAASARPSR 316



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 47/167 (28%), Positives = 54/167 (32%), Gaps = 41/167 (24%)

Query: 162 RGGAGQALAQVERGAVGRAEDLQAGAGPRGAAEAQAPQLLGVGSAGLAAVVGDEAQALAA 221
           RG    A  +  RGA   A    A A P   A    P  +       AA      +A AA
Sbjct: 104 RGATPPAPPRAPRGAPAAAA---AAAPPPTPAPPPPPAPVA------AAAPARAPRAAAA 154

Query: 222 GSQRPQGLGRARHGGLPAPQHAVAVEQQRVHVGQQRLCPLGAQPHAAGVVATGLRRRHRR 281
            +  P   G A+    P P+              QR  PL A P A              
Sbjct: 155 AATAPPSPGPAQ----PGPR-------------AQRAAPLAAPPPAPAA----------- 186

Query: 282 PPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFANPPPPP 328
           PPA A      A  RR   PA  A   P P   +P A      PPPP
Sbjct: 187 PPAVAPP----AGPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPP 229



 Score = 30.4 bits (67), Expect = 4.0
 Identities = 25/73 (34%), Positives = 26/73 (35%), Gaps = 3/73 (4%)

Query: 264 QPHAAGVVATGLRRRHRRPPAAAARRPLLAAARRGALPAPGALIGPAPRARRPLACTFAN 323
           QP   G       R  R  PAAAA     A     A P P A +  A  AR P A   A 
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAA---APPPTPAPPPPPAPVAAAAPARAPRAAAAAA 156

Query: 324 PPPPPAGCGSSAP 336
             PP  G     P
Sbjct: 157 TAPPSPGPAQPGP 169


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.135    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,378,989
Number of Sequences: 37866
Number of extensions: 1504671
Number of successful extensions: 9543
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 700
Number of HSP's that attempted gapping in prelim test: 8046
Number of HSP's gapped (non-prelim): 1899
length of query: 513
length of database: 18,247,518
effective HSP length: 107
effective length of query: 406
effective length of database: 14,195,856
effective search space: 5763517536
effective search space used: 5763517536
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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