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Search of human proteins with 11641275
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|11641275 potassium family, subfamily K, member 15 [Homo
sapiens]
(330 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens] 669 0.0
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens] 339 2e-93
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens] 330 1e-90
gi|205360983 potassium channel, subfamily K, member 16 isoform 3... 130 1e-30
gi|14589851 potassium channel, subfamily K, member 2 isoform b [... 130 2e-30
gi|126365795 potassium channel, subfamily K, member 2 isoform c ... 130 2e-30
gi|62912487 potassium channel, subfamily K, member 2 isoform a [... 130 2e-30
gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ... 129 3e-30
gi|205360973 potassium channel, subfamily K, member 16 isoform 4... 125 4e-29
gi|205360971 potassium channel, subfamily K, member 16 isoform 1... 125 4e-29
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ... 122 3e-28
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ... 122 3e-28
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ... 122 3e-28
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens] 118 8e-27
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi... 117 1e-26
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ... 116 2e-26
gi|15718767 TRAAK [Homo sapiens] 114 1e-25
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens] 114 1e-25
gi|205361107 potassium channel, subfamily K, member 17 isoform 2... 112 6e-25
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi... 105 6e-23
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens] 103 2e-22
gi|16118231 potassium channel, subfamily K, member 7 isoform A [... 89 5e-18
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H... 87 2e-17
gi|16118235 potassium channel, subfamily K, member 7 isoform B [... 87 2e-17
gi|16118233 potassium channel, subfamily K, member 7 isoform B [... 87 2e-17
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi... 67 2e-11
gi|13540549 potassium voltage-gated channel, subfamily H, member... 40 0.003
gi|4504859 intermediate conductance calcium-activated potassium ... 40 0.004
gi|27436984 potassium voltage-gated channel, Shal-related subfam... 40 0.004
gi|27436986 potassium voltage-gated channel, Shal-related subfam... 40 0.004
>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
Length = 330
Score = 669 bits (1727), Expect = 0.0
Identities = 330/330 (100%), Positives = 330/330 (100%)
Query: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR
Sbjct: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
Query: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL
Sbjct: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH
Sbjct: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
Query: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN
Sbjct: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
Query: 241 LVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCA 300
LVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCA
Sbjct: 241 LVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPARSVGSASVFCHVHKLERCA 300
Query: 301 RDNLGFSPPSSPGVVRGGQAPRPGARWKSI 330
RDNLGFSPPSSPGVVRGGQAPRPGARWKSI
Sbjct: 301 RDNLGFSPPSSPGVVRGGQAPRPGARWKSI 330
>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
Length = 374
Score = 339 bits (869), Expect = 2e-93
Identities = 175/283 (61%), Positives = 207/283 (73%), Gaps = 1/283 (0%)
Query: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
M+R +VR L++CT YLLVGAAVFDALES+ E + L + ++ K+ S+EDYR
Sbjct: 1 MKRQNVRTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYR 60
Query: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
+LE + LQ+EPHRAG QWKF GSFYFAITVITTIGYGHAAPGTD+GK FCMFYA+LGIPL
Sbjct: 61 QLELVILQSEPHRAGVQWKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVLGIPL 120
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
TLV FQSLGER+N VR LL K C G+R T VS EN+V G +C TL +GA AFS
Sbjct: 121 TLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCIGAAAFSQ 180
Query: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
E W+FFHAYYYCFITLTTIGFGD+VALQ+ ALQ+K YVAFSF+YIL+GLTVIGAFLN
Sbjct: 181 CEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLTVIGAFLN 240
Query: 241 LVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPARS 283
LVVLRFL +++ ER G S + +P P S
Sbjct: 241 LVVLRFLTMNSE-DERRDAEERASLAGNRNSMVIHIPEEPRPS 282
>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
Length = 394
Score = 330 bits (846), Expect = 1e-90
Identities = 167/258 (64%), Positives = 199/258 (77%)
Query: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYR 60
M+R +VR L++CT YLLVGAAVFDALESE E ++ L ++ LR ++ S Y
Sbjct: 1 MKRQNVRTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYNLSQGGYE 60
Query: 61 ELERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
ELER+ L+ +PH+AG QW+F GSFYFAITVITTIGYGHAAP TD GKVFCMFYALLGIPL
Sbjct: 61 ELERVVLRLKPHKAGVQWRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLGIPL 120
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
TLV FQSLGER+N +VR LL AK LG+R VS N+V+ G +C +TL +GA AFSH
Sbjct: 121 TLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVLIGFFSCISTLCIGAAAFSH 180
Query: 181 FEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIGAFLN 240
+E WTFF AYYYCFITLTTIGFGD+VALQ +ALQ + YVAFSF+YIL GLTVIGAFLN
Sbjct: 181 YEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLTVIGAFLN 240
Query: 241 LVVLRFLVASADWPERAA 258
LVVLRF+ +A+ +R A
Sbjct: 241 LVVLRFMTMNAEDEKRDA 258
>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
[Homo sapiens]
Length = 294
Score = 130 bits (328), Expect = 1e-30
Identities = 98/292 (33%), Positives = 142/292 (48%), Gaps = 38/292 (13%)
Query: 7 RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65
R L+L +CYLL+GA +F LE +AE+ R + ++K L + ++
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117
++A + W F SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175
IPL ++ LG L A + + RW + V+ +L A L LG
Sbjct: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
Query: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYIL 229
+ FSH EGW+F +Y+ FITL+TIGFGD+V + + + Y + + ++IL
Sbjct: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWIL 241
Query: 230 LGLTVIGAFLNLVVLRFLVASADW--------PERAARPPS--PRPPGAPES 271
LGL + L L L W + AA PS PRP P S
Sbjct: 242 LGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPRPQKIPIS 293
>gi|14589851 potassium channel, subfamily K, member 2 isoform b
[Homo sapiens]
Length = 411
Score = 130 bits (326), Expect = 2e-30
Identities = 81/246 (32%), Positives = 129/246 (52%), Gaps = 17/246 (6%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAE-SGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
+ L + YL++GA VF ALE E S R +++QK+ + + ++ + EL + + A
Sbjct: 50 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 109
Query: 70 ---------EPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
W SF+FA TVITTIG+G+ +P T+ GK+FC+ YALLGIPL
Sbjct: 110 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 169
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTE----NLVVAGLLACAATLALGAV 176
+G++L + + + + ++W T+ + ++ L C +AL A+
Sbjct: 170 FGFLLAGVGDQLGTIFGKGIAKVEDTF-IKWNVSQTKIRIISTIIFILFGCVLFVALPAI 228
Query: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
F H EGW+ A Y+ ITLTTIGFGD+VA G ++ Y + +IL+GL
Sbjct: 229 IFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVWFWILVGLAYFA 286
Query: 237 AFLNLV 242
A L+++
Sbjct: 287 AVLSMI 292
>gi|126365795 potassium channel, subfamily K, member 2 isoform c
[Homo sapiens]
Length = 426
Score = 130 bits (326), Expect = 2e-30
Identities = 81/246 (32%), Positives = 129/246 (52%), Gaps = 17/246 (6%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAE-SGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
+ L + YL++GA VF ALE E S R +++QK+ + + ++ + EL + + A
Sbjct: 65 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 124
Query: 70 ---------EPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
W SF+FA TVITTIG+G+ +P T+ GK+FC+ YALLGIPL
Sbjct: 125 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 184
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTE----NLVVAGLLACAATLALGAV 176
+G++L + + + + ++W T+ + ++ L C +AL A+
Sbjct: 185 FGFLLAGVGDQLGTIFGKGIAKVEDTF-IKWNVSQTKIRIISTIIFILFGCVLFVALPAI 243
Query: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
F H EGW+ A Y+ ITLTTIGFGD+VA G ++ Y + +IL+GL
Sbjct: 244 IFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVWFWILVGLAYFA 301
Query: 237 AFLNLV 242
A L+++
Sbjct: 302 AVLSMI 307
>gi|62912487 potassium channel, subfamily K, member 2 isoform a
[Homo sapiens]
Length = 422
Score = 130 bits (326), Expect = 2e-30
Identities = 81/246 (32%), Positives = 129/246 (52%), Gaps = 17/246 (6%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAE-SGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
+ L + YL++GA VF ALE E S R +++QK+ + + ++ + EL + + A
Sbjct: 61 IFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQIVAA 120
Query: 70 ---------EPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
W SF+FA TVITTIG+G+ +P T+ GK+FC+ YALLGIPL
Sbjct: 121 INAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLGIPL 180
Query: 121 TLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTE----NLVVAGLLACAATLALGAV 176
+G++L + + + + ++W T+ + ++ L C +AL A+
Sbjct: 181 FGFLLAGVGDQLGTIFGKGIAKVEDTF-IKWNVSQTKIRIISTIIFILFGCVLFVALPAI 239
Query: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
F H EGW+ A Y+ ITLTTIGFGD+VA G ++ Y + +IL+GL
Sbjct: 240 IFKHIEGWSALDAIYFVVITLTTIGFGDYVA--GGSDIEYLDFYKPVVWFWILVGLAYFA 297
Query: 237 AFLNLV 242
A L+++
Sbjct: 298 AVLSMI 303
>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
Length = 309
Score = 129 bits (325), Expect = 3e-30
Identities = 87/252 (34%), Positives = 130/252 (51%), Gaps = 28/252 (11%)
Query: 7 RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65
R L+L +CYLL+GA +F LE +AE+ R + ++K L + ++
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117
++A + W F SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175
IPL ++ LG L A + + RW + V+ +L A L LG
Sbjct: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
Query: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYIL 229
+ FSH EGW+F +Y+ FITL+TIGFGD+V + + + Y + + ++IL
Sbjct: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWIL 241
Query: 230 LGLTVIGAFLNL 241
LGL + L L
Sbjct: 242 LGLAWLALILPL 253
>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
[Homo sapiens]
Length = 262
Score = 125 bits (315), Expect = 4e-29
Identities = 79/217 (36%), Positives = 114/217 (52%), Gaps = 27/217 (12%)
Query: 7 RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65
R L+L +CYLL+GA +F LE +AE+ R + ++K L + ++
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117
++A + W F SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175
IPL ++ LG L A + + RW + V+ +L A L LG
Sbjct: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
Query: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFV 206
+ FSH EGW+F +Y+ FITL+TIGFGD+V
Sbjct: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
Score = 30.4 bits (67), Expect = 2.3
Identities = 12/29 (41%), Positives = 15/29 (51%)
Query: 78 WKFPGSFYFAITVITTIGYGHAAPGTDSG 106
W F FYFA ++TIG+G G G
Sbjct: 197 WSFSEGFYFAFITLSTIGFGDYVVGLRQG 225
>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
[Homo sapiens]
Length = 322
Score = 125 bits (315), Expect = 4e-29
Identities = 79/217 (36%), Positives = 114/217 (52%), Gaps = 27/217 (12%)
Query: 7 RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65
R L+L +CYLL+GA +F LE +AE+ R + ++K L + ++
Sbjct: 13 RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
Query: 66 ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117
++A + W F SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 73 IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
Query: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175
IPL ++ LG L A + + RW + V+ +L A L LG
Sbjct: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
Query: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFV 206
+ FSH EGW+F +Y+ FITL+TIGFGD+V
Sbjct: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV 219
Score = 29.3 bits (64), Expect = 5.1
Identities = 11/25 (44%), Positives = 14/25 (56%)
Query: 78 WKFPGSFYFAITVITTIGYGHAAPG 102
W F FYFA ++TIG+G G
Sbjct: 197 WSFSEGFYFAFITLSTIGFGDYVVG 221
>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
[Homo sapiens]
Length = 543
Score = 122 bits (307), Expect = 3e-28
Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 20/248 (8%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLL-VQKRGALRRKFGFSAEDYRELERLALQA 69
+ + + YL+ G VF ALE ES ++ + ++K LR S ++ L + AL A
Sbjct: 80 IFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDA 139
Query: 70 E---------PHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
+ W +F+FA TVITTIGYG+ AP T+ GK+FC+ YA+ GIPL
Sbjct: 140 DNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 199
Query: 121 TLVTFQSLGERLNAVVRRLL------LAAKCCLGLRWTCVSTENLVVAGLLACAATLALG 174
+G++L + + + K + +ST ++AG C + +
Sbjct: 200 FGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAG---CIVFVTIP 256
Query: 175 AVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTV 234
AV F + EGWT + Y+ +TLTT+GFGDFVA + + Y + +IL+GL
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAY 315
Query: 235 IGAFLNLV 242
A L+++
Sbjct: 316 FAAVLSMI 323
>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
[Homo sapiens]
Length = 543
Score = 122 bits (307), Expect = 3e-28
Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 20/248 (8%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLL-VQKRGALRRKFGFSAEDYRELERLALQA 69
+ + + YL+ G VF ALE ES ++ + ++K LR S ++ L + AL A
Sbjct: 80 IFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDA 139
Query: 70 E---------PHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
+ W +F+FA TVITTIGYG+ AP T+ GK+FC+ YA+ GIPL
Sbjct: 140 DNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 199
Query: 121 TLVTFQSLGERLNAVVRRLL------LAAKCCLGLRWTCVSTENLVVAGLLACAATLALG 174
+G++L + + + K + +ST ++AG C + +
Sbjct: 200 FGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAG---CIVFVTIP 256
Query: 175 AVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTV 234
AV F + EGWT + Y+ +TLTT+GFGDFVA + + Y + +IL+GL
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAY 315
Query: 235 IGAFLNLV 242
A L+++
Sbjct: 316 FAAVLSMI 323
>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
[Homo sapiens]
Length = 538
Score = 122 bits (307), Expect = 3e-28
Identities = 78/248 (31%), Positives = 123/248 (49%), Gaps = 20/248 (8%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLL-VQKRGALRRKFGFSAEDYRELERLALQA 69
+ + + YL+ G VF ALE ES ++ + ++K LR S ++ L + AL A
Sbjct: 75 IFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHALDA 134
Query: 70 E---------PHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
+ W +F+FA TVITTIGYG+ AP T+ GK+FC+ YA+ GIPL
Sbjct: 135 DNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFGIPL 194
Query: 121 TLVTFQSLGERLNAVVRRLL------LAAKCCLGLRWTCVSTENLVVAGLLACAATLALG 174
+G++L + + + K + +ST ++AG C + +
Sbjct: 195 FGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAG---CIVFVTIP 251
Query: 175 AVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTV 234
AV F + EGWT + Y+ +TLTT+GFGDFVA + + Y + +IL+GL
Sbjct: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVA-GGNAGINYREWYKPLVWFWILVGLAY 310
Query: 235 IGAFLNLV 242
A L+++
Sbjct: 311 FAAVLSMI 318
>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
Length = 499
Score = 118 bits (295), Expect = 8e-27
Identities = 86/251 (34%), Positives = 124/251 (49%), Gaps = 22/251 (8%)
Query: 11 LVLCTLCYLLVGAAVFDALESEA-ESGRQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
L + YL +GAA+F+ LE + ++ QK L+ F L+++ L+
Sbjct: 8 LTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKE---FPCLGQEGLDKI-LEV 63
Query: 70 EPHRAGR-----------QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGI 118
AG+ W +P + FA TVITTIGYG+ AP T +G++FC+FY L G+
Sbjct: 64 VSDAAGQGVAITGNQTFNNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGV 123
Query: 119 PLTLVTFQSLGERLNAVVRRL-LLAAKCCLGLRWTCVS-TENLVVAGLLACAATLALGAV 176
PL L +LG+ +RL K + LR ++ T +V G+L L +
Sbjct: 124 PLCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVL---VHLVIPPF 180
Query: 177 AFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVIG 236
F EGW + YY FIT++TIGFGDFVA + A L Y F L+I LGL +
Sbjct: 181 VFMVTEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHAL-YRYFVELWIYLGLAWLS 239
Query: 237 AFLNLVVLRFL 247
F+N V F+
Sbjct: 240 LFVNWKVSMFV 250
>gi|16306555 potassium channel, subfamily K, member 13 [Homo
sapiens]
Length = 408
Score = 117 bits (294), Expect = 1e-26
Identities = 90/311 (28%), Positives = 146/311 (46%), Gaps = 36/311 (11%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED-------YRELE 63
L + YLL GAAVF ALE E ++ ++ R S ++ Y E
Sbjct: 23 LAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHNLSRDELRGFLRHYEEAT 82
Query: 64 RLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLV 123
R ++ + R +W F G+FYF TV++TIG+G P T GK+F +FY L+G T++
Sbjct: 83 RAGIRVDNVRP--RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVGCSSTIL 140
Query: 124 TFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAG------------------LL 165
F ERL ++ ++ + R + E+L AG L+
Sbjct: 141 FFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSVYYVMLI 200
Query: 166 ACAATLALGAVA---FSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVA 222
C A++ + A ++ EGW++F + Y+CF+ +TIGFGD V+ Q+ + L Y
Sbjct: 201 LCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLVSSQNAHYESQGL-YRF 259
Query: 223 FSFLYILLGLTVIGAFLNLVVLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRPAR 282
+F++IL+G+ I + N++ + + S +W R + S P RGL RR
Sbjct: 260 ANFVFILMGVCCIYSLFNVISI-LIKQSLNWILR--KMDSGCCPQC--QRGLLRSRRNVV 314
Query: 283 SVGSASVFCHV 293
GS C++
Sbjct: 315 MPGSVRNRCNI 325
>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
[Homo sapiens]
Length = 332
Score = 116 bits (291), Expect = 2e-26
Identities = 79/248 (31%), Positives = 123/248 (49%), Gaps = 23/248 (9%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFG-FSAEDYRELERLALQA 69
L+L L YL +G VF LE A R + + L + F L R +QA
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 70 EPHRAGR--------QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLT 121
+ A +W+ GSF+F+++ ITTIGYG+ +P T + ++FC+F+AL+GIPL
Sbjct: 85 YKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLN 144
Query: 122 LVTFQSLGERLNAVVRRLLLAAKCCLGLRW------TCVSTENLVVAGLLACAATLALGA 175
LV LG + V LG W ++ +++GLL L L
Sbjct: 145 LVVLNRLGHLMQQGVNHWASR----LGGTWQDPDKARWLAGSGALLSGLL---LFLLLPP 197
Query: 176 VAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGLTVI 235
+ FSH EGW++ +Y+ FITL+T+GFGD+V + + + L Y L+IL G+ +
Sbjct: 198 LLFSHMEGWSYTEGFYFAFITLSTVGFGDYV-IGMNPSQRYPLWYKNMVSLWILFGMAWL 256
Query: 236 GAFLNLVV 243
+ L++
Sbjct: 257 ALIIKLIL 264
>gi|15718767 TRAAK [Homo sapiens]
Length = 393
Score = 114 bits (285), Expect = 1e-25
Identities = 96/316 (30%), Positives = 144/316 (45%), Gaps = 38/316 (12%)
Query: 5 SVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAEDYREL-- 62
S L+ L YL+ GA VF ALE E QR L + R R ++ L
Sbjct: 3 STTLLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLI 62
Query: 63 ----ERLALQAEP------HRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMF 112
+ L A+P + + W +F+F+ T+ITTIGYG+ A TD+G++FC+F
Sbjct: 63 KEVADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIF 122
Query: 113 YALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRW----TCVSTENLVVAGLLACA 168
YAL+GIPL + +G+RL + +R + + + L+W V + ++ L+ C
Sbjct: 123 YALVGIPLFGILLAGVGDRLGSSLRHGIGHIE-AIFLKWHVPPELVRVLSAMLFLLIGCL 181
Query: 169 ATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYI 228
+ F + E W+ A Y+ +TLTT+GFGD+VA + Q Y + +I
Sbjct: 182 LFVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVA--GADPRQDSPAYQPLVWFWI 239
Query: 229 LLG-------LTVIGAFLNLVVLR-------FLVASADW----PERAARPPSP-RPPGAP 269
LLG LT IG +L +V R +A W R + P PP
Sbjct: 240 LLGLAYFASVLTTIGNWLRVVSRRTRAEMGGLTAQAASWTGTVTARVTQRAGPAAPPPEK 299
Query: 270 ESRGLWLPRRPARSVG 285
E L P PA+ +G
Sbjct: 300 EQPLLPPPPCPAQPLG 315
>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
Length = 336
Score = 114 bits (285), Expect = 1e-25
Identities = 77/233 (33%), Positives = 116/233 (49%), Gaps = 12/233 (5%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESG-RQRLLVQKRGALRRKFGFSAEDYRELERLALQA 69
LVL L YL+ GA VF ++E E RQ L KR L S + + L+A
Sbjct: 26 LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85
Query: 70 EPH--------RAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLT 121
+ W F + +FA TV++T GYGH P +D GK FC+ Y+++GIP T
Sbjct: 86 SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145
Query: 122 LVTFQSLGERLNA-VVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGAVAFSH 180
L+ ++ +R+ V RR +L G V+ + V+ G + + + A FS
Sbjct: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205
Query: 181 FE-GWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYILLGL 232
E W F ++Y+CFI+L+TIG GD+V + R+L + + Y+LLGL
Sbjct: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGIT-CYLLLGL 257
>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
[Homo sapiens]
Length = 271
Score = 112 bits (279), Expect = 6e-25
Identities = 72/211 (34%), Positives = 107/211 (50%), Gaps = 22/211 (10%)
Query: 11 LVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFG-FSAEDYRELERLALQA 69
L+L L YL +G VF LE A R + + L + F L R +QA
Sbjct: 25 LLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCLDRPALDSLIRDVVQA 84
Query: 70 EPHRAGR--------QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLT 121
+ A +W+ GSF+F+++ ITTIGYG+ +P T + ++FC+F+AL+GIPL
Sbjct: 85 YKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAARLFCIFFALVGIPLN 144
Query: 122 LVTFQSLGERLNAVVRRLLLAAKCCLGLRW------TCVSTENLVVAGLLACAATLALGA 175
LV LG + V LG W ++ +++GLL L L
Sbjct: 145 LVVLNRLGHLMQQGVNHWASR----LGGTWQDPDKARWLAGSGALLSGLL---LFLLLPP 197
Query: 176 VAFSHFEGWTFFHAYYYCFITLTTIGFGDFV 206
+ FSH EGW++ +Y+ FITL+T+GFGD+V
Sbjct: 198 LLFSHMEGWSYTEGFYFAFITLSTVGFGDYV 228
>gi|11545761 potassium channel, subfamily K, member 12 [Homo
sapiens]
Length = 430
Score = 105 bits (262), Expect = 6e-23
Identities = 95/306 (31%), Positives = 138/306 (45%), Gaps = 52/306 (16%)
Query: 18 YLLVGAAVFDALESEAESGRQRLLVQKRGALRRKF----GFSAEDYRELER-----LALQ 68
YL+ GA VF ALES E+ + + GA R F G + + R R LA
Sbjct: 49 YLVAGATVFSALESPGEAEARA----RWGATLRNFSAAHGVAEPELRAFLRHYEAALAAG 104
Query: 69 AEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSL 128
+W FPG+FYF TV++TIG+G P T GK F + Y L G T++ F
Sbjct: 105 VRADALRPRWDFPGAFYFVGTVVSTIGFGMTTPATVGGKAFLIAYGLFGCAGTILFFNLF 164
Query: 129 GERLNAVV-------------RRLLLAAKCCLGLR---------WTCVSTENLVVAGLLA 166
ER+ +++ R LL A G W L++ GL A
Sbjct: 165 LERIISLLAFIMRACRERQLRRSGLLPATFRRGSALSEADSLAGWKPSVYHVLLILGLFA 224
Query: 167 CAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFL 226
+ A+ ++ EGW + + Y+CF+T +TIGFGD V+ Q A + + Y +FL
Sbjct: 225 VLLSCCASAM-YTSVEGWDYVDSLYFCFVTFSTIGFGDLVSSQHA-AYRNQGLYRLGNFL 282
Query: 227 YILLGLTVIGAFLNLV------VLRFLVASADWPERAARPPSPRPPGAPESRGLWLPRRP 280
+ILLG+ I + N++ VL +++ A P+ PGAP L RR
Sbjct: 283 FILLGVCCIYSLFNVISILIKQVLNWMLRKLSCRCCARCCPA---PGAP------LARRN 333
Query: 281 ARSVGS 286
A + GS
Sbjct: 334 AITPGS 339
>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
Length = 313
Score = 103 bits (257), Expect = 2e-22
Identities = 77/254 (30%), Positives = 124/254 (48%), Gaps = 24/254 (9%)
Query: 1 MRRPSVRAAGLVLCTLCYLLVGAAVFDALE--------SEAESGRQRLLVQKRGALRRKF 52
MRR ++ AG + YL++GA + LE +E E+ R +LL +
Sbjct: 1 MRRGAL-LAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPAL 59
Query: 53 GFSAEDYRELERLALQAEPHRAGRQ------WKFPGSFYFAITVITTIGYGHAAPGTDSG 106
E RL + +G W F + +FA T+ITT+GYG+ P TD+G
Sbjct: 60 DAFVERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAG 119
Query: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRW----TCVSTENLVVA 162
K F + +ALLG+P T++ + +RL+ ++ + L+ L +RW + +LV
Sbjct: 120 KAFSIAFALLGVPTTMLLLTASAQRLSLLLTHVPLS---WLSMRWGWDPRRAACWHLVAL 176
Query: 163 GLLACAATLALGAVAFSHF-EGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYV 221
+ + AV F+H E W+F A+Y+CFI+L+TIG GD+V ++ R L Y
Sbjct: 177 LGVVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRAL-YK 235
Query: 222 AFSFLYILLGLTVI 235
+Y+ LGL +
Sbjct: 236 VLVTVYLFLGLVAM 249
>gi|16118231 potassium channel, subfamily K, member 7 isoform A
[Homo sapiens]
Length = 307
Score = 89.0 bits (219), Expect = 5e-18
Identities = 80/253 (31%), Positives = 112/253 (44%), Gaps = 34/253 (13%)
Query: 3 RPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED---- 58
RP R LV+ L L +GA VF ALE RL + R L F AE
Sbjct: 5 RPWSRYGLLVVAHLLALGLGAVVFQALEGPPAC---RLQAELRAELA---AFQAEHRACL 58
Query: 59 ----YRELERLALQAEPHRA--------GRQWKFPGSFYFAITVITTIGYGHAAPGTDSG 106
EL AL + H GR W P + FA +++TT GYGH AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
Query: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTC----VSTENLVVA 162
K FCM YA LG+P +L +L L V+ R + + + W + V
Sbjct: 119 KAFCMVYAALGLPASLALVATLRHCLLPVLSR----PRAWVAVHWQLSPARAALLQAVAL 174
Query: 163 GLLACAATLALGAVAFSHFEG-WTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYV 221
GLL ++ + L A+ +G + A Y+CF +L+TIG D + G +L + ++
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLLP-GRGRSLHPVIYHL 233
Query: 222 AFSFL--YILLGL 232
L Y+LLGL
Sbjct: 234 GQLALLGYLLLGL 246
>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
sapiens]
Length = 257
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/225 (32%), Positives = 99/225 (44%), Gaps = 31/225 (13%)
Query: 3 RPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED---- 58
RP R LV+ L L +GA VF ALE RL + R L F AE
Sbjct: 5 RPWSRYGLLVVAHLLALGLGAVVFQALEGPPAC---RLQAELRAELA---AFQAEHRACL 58
Query: 59 ----YRELERLALQAEPHRA--------GRQWKFPGSFYFAITVITTIGYGHAAPGTDSG 106
EL AL + H GR W P + FA +++TT GYGH AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
Query: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTC----VSTENLVVA 162
K FCM YA LG+P +L +L L V+ R + + + W + V
Sbjct: 119 KAFCMVYAALGLPASLALVATLRHCLLPVLSR----PRAWVAVHWQLSPARAALLQAVAL 174
Query: 163 GLLACAATLALGAVAFSHFEG-WTFFHAYYYCFITLTTIGFGDFV 206
GLL ++ + L A+ +G + A Y+CF +L+TIG D +
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219
>gi|16118235 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/225 (32%), Positives = 99/225 (44%), Gaps = 31/225 (13%)
Query: 3 RPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED---- 58
RP R LV+ L L +GA VF ALE RL + R L F AE
Sbjct: 5 RPWSRYGLLVVAHLLALGLGAVVFQALEGPPAC---RLQAELRAELA---AFQAEHRACL 58
Query: 59 ----YRELERLALQAEPHRA--------GRQWKFPGSFYFAITVITTIGYGHAAPGTDSG 106
EL AL + H GR W P + FA +++TT GYGH AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
Query: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTC----VSTENLVVA 162
K FCM YA LG+P +L +L L V+ R + + + W + V
Sbjct: 119 KAFCMVYAALGLPASLALVATLRHCLLPVLSR----PRAWVAVHWQLSPARAALLQAVAL 174
Query: 163 GLLACAATLALGAVAFSHFEG-WTFFHAYYYCFITLTTIGFGDFV 206
GLL ++ + L A+ +G + A Y+CF +L+TIG D +
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219
>gi|16118233 potassium channel, subfamily K, member 7 isoform B
[Homo sapiens]
Length = 252
Score = 87.4 bits (215), Expect = 2e-17
Identities = 72/225 (32%), Positives = 99/225 (44%), Gaps = 31/225 (13%)
Query: 3 RPSVRAAGLVLCTLCYLLVGAAVFDALESEAESGRQRLLVQKRGALRRKFGFSAED---- 58
RP R LV+ L L +GA VF ALE RL + R L F AE
Sbjct: 5 RPWSRYGLLVVAHLLALGLGAVVFQALEGPPAC---RLQAELRAELA---AFQAEHRACL 58
Query: 59 ----YRELERLALQAEPHRA--------GRQWKFPGSFYFAITVITTIGYGHAAPGTDSG 106
EL AL + H GR W P + FA +++TT GYGH AP + G
Sbjct: 59 PPGALEELLGTALATQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGG 118
Query: 107 KVFCMFYALLGIPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTC----VSTENLVVA 162
K FCM YA LG+P +L +L L V+ R + + + W + V
Sbjct: 119 KAFCMVYAALGLPASLALVATLRHCLLPVLSR----PRAWVAVHWQLSPARAALLQAVAL 174
Query: 163 GLLACAATLALGAVAFSHFEG-WTFFHAYYYCFITLTTIGFGDFV 206
GLL ++ + L A+ +G + A Y+CF +L+TIG D +
Sbjct: 175 GLLVASSFVLLPALVLWGLQGDCSLLGAVYFCFSSLSTIGLEDLL 219
>gi|32469495 potassium channel, subfamily K, member 18 [Homo
sapiens]
Length = 384
Score = 67.4 bits (163), Expect = 2e-11
Identities = 45/136 (33%), Positives = 65/136 (47%), Gaps = 12/136 (8%)
Query: 13 LCTLCYL----LVGAAVFDALES-----EAESGRQRLLVQKRGALRRKFGFSAEDYRE-L 62
LC LC+L LVGA VF A+E A+ G +++ + ED ++ L
Sbjct: 24 LCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEKFLEELCRILNCSETVVEDRKQDL 83
Query: 63 ERLALQAEPHRAGR--QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPL 120
+ + +P R W F S +F TV +T+GYG+ P T GK CM YAL GIPL
Sbjct: 84 QGHLQKVKPQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLCMLYALFGIPL 143
Query: 121 TLVTFQSLGERLNAVV 136
+ G+ L ++
Sbjct: 144 MFLVLTDTGDILATIL 159
Score = 45.1 bits (105), Expect = 9e-05
Identities = 30/89 (33%), Positives = 48/89 (53%), Gaps = 13/89 (14%)
Query: 159 LVVAGLLACAATLALGAVAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKL 218
L+V ++CAA + FE +A+Y+CF+TLTTIGFGD V L+
Sbjct: 288 LIVFAYISCAAAILPFWETQLDFE-----NAFYFCFVTLTTIGFGDTV-------LEHPN 335
Query: 219 PYVAFSFLYILLGLTVIGAFLNLVVLRFL 247
++ FS +YI++G+ ++ LV R +
Sbjct: 336 FFLFFS-IYIIVGMEIVFIAFKLVQNRLI 363
Score = 38.1 bits (87), Expect = 0.011
Identities = 17/65 (26%), Positives = 33/65 (50%)
Query: 77 QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVV 136
Q F +FYF +TTIG+G + +F Y ++G+ + + F+ + RL +
Sbjct: 307 QLDFENAFYFCFVTLTTIGFGDTVLEHPNFFLFFSIYIIVGMEIVFIAFKLVQNRLIDIY 366
Query: 137 RRLLL 141
+ ++L
Sbjct: 367 KNVML 371
>gi|13540549 potassium voltage-gated channel, subfamily H, member 6
isoform 1 [Homo sapiens]
Length = 994
Score = 40.0 bits (92), Expect = 0.003
Identities = 19/63 (30%), Positives = 39/63 (61%), Gaps = 4/63 (6%)
Query: 77 QWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTLVTFQSLGERLNAVV 136
Q K+ + YF + +T++G+G+ +P T+S KVF + L+G + + S+ ++A++
Sbjct: 460 QDKYVTALYFTFSSLTSVGFGNVSPNTNSEKVFSICVMLIG----SLMYASIFGNVSAII 515
Query: 137 RRL 139
+RL
Sbjct: 516 QRL 518
>gi|4504859 intermediate conductance calcium-activated potassium
channel protein 1 [Homo sapiens]
Length = 427
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/70 (31%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 63 ERLALQAEPHRAGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGIPLTL 122
ER A+ A H + W P +F TIGYG PGT GK+ C+ ++G+ T
Sbjct: 227 ERQAVNATGHLSDTLWLIPITFL-------TIGYGDVVPGTMWGKIVCLCTGVMGVCCTA 279
Query: 123 VTFQSLGERL 132
+ + +L
Sbjct: 280 LLVAVVARKL 289
>gi|27436984 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 1 [Homo sapiens]
Length = 655
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 74 AGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGI 118
A + P SF++ I +TT+GYG P T +GK+F +L G+
Sbjct: 348 ASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGV 392
>gi|27436986 potassium voltage-gated channel, Shal-related
subfamily, member 3 isoform 2 [Homo sapiens]
Length = 636
Score = 39.7 bits (91), Expect = 0.004
Identities = 17/45 (37%), Positives = 26/45 (57%)
Query: 74 AGRQWKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLGI 118
A + P SF++ I +TT+GYG P T +GK+F +L G+
Sbjct: 348 ASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGV 392
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.141 0.449
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,711,456
Number of Sequences: 37866
Number of extensions: 641514
Number of successful extensions: 4860
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 110
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 4543
Number of HSP's gapped (non-prelim): 276
length of query: 330
length of database: 18,247,518
effective HSP length: 103
effective length of query: 227
effective length of database: 14,347,320
effective search space: 3256841640
effective search space used: 3256841640
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.