Search of human proteins with 116325993

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
         (1700 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]        3448   0.0  
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]       3421   0.0  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...  3411   0.0  
gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...  3248   0.0  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...  3199   0.0  
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...  1743   0.0  
gi|53829385 leucine rich repeat containing 37B [Homo sapiens]         751   0.0  
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  106   2e-22
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   106   2e-22
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  106   2e-22
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  106   2e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    95   5e-19
gi|91982772 mucin 17 [Homo sapiens]                                    90   2e-17
gi|224458301 family with sequence similarity 186, member A [Homo...    89   4e-17
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              89   4e-17
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    87   1e-16
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             85   5e-16
gi|116284392 mucin 2 precursor [Homo sapiens]                          85   5e-16
gi|151301154 mucin 6, gastric [Homo sapiens]                           84   9e-16
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       84   1e-15
gi|110349719 titin isoform N2-A [Homo sapiens]                         81   1e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    80   2e-14
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit...    80   2e-14
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        79   3e-14
gi|146134388 YLP motif containing 1 [Homo sapiens]                     78   6e-14
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          77   1e-13
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          77   1e-13
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          76   3e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             75   5e-13
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        72   4e-12

>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 3448 bits (8941), Expect = 0.0
 Identities = 1700/1700 (100%), Positives = 1700/1700 (100%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
            MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440
            HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 3421 bits (8871), Expect = 0.0
 Identities = 1691/1700 (99%), Positives = 1693/1700 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
            MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+SW
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRT K
Sbjct: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380

Query: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440
            HFIE NNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKD+YKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDLYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 2 [Homo sapiens]
          Length = 1700

 Score = 3411 bits (8844), Expect = 0.0
 Identities = 1685/1700 (99%), Positives = 1687/1700 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+ W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440
            HFIE NNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 GIFRFLPWRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680
            GIFRFLP RGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL
Sbjct: 1621 GIFRFLPRRGCSSRRESQDGLSSFGQPLWFKDMYKPLSATRINNHAWKLHKKSSNEDKIL 1680

Query: 1681 NRDPGDSEAPTEEEESEALP 1700
            NRDPGDSEAPTEEEESEALP
Sbjct: 1681 NRDPGDSEAPTEEEESEALP 1700


>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 1 [Homo sapiens]
          Length = 1635

 Score = 3248 bits (8422), Expect = 0.0
 Identities = 1606/1620 (99%), Positives = 1608/1620 (99%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+ W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440
            HFIE NNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 19/31 (61%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 1670 HKKSSNEDKILNRDPGDSEAPTEEEESEALP 1700
            H++S  ED+       DSEAPTEEEESEALP
Sbjct: 1607 HRRSLQEDE--EGFSRDSEAPTEEEESEALP 1635


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
            sapiens]
          Length = 1634

 Score = 3199 bits (8294), Expect = 0.0
 Identities = 1580/1620 (97%), Positives = 1594/1620 (98%)

Query: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+ W
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI  QLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSES REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQ PDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI+
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140
            TSTELI+EPEEPSDSSGINLSGFGSEQLDTNDESD  STLSYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            FIKLPTTGNSLAKIQTVG+NRQR+ RVLMGPRSIQKRHFKEVGRQSIRREQGAQASVEN 
Sbjct: 1141 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPRE++QPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTN KTSKPIVH+RKKYRFHKTRS +THRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLML+NRLPFSAAKSLINSPSQGAFSSL DLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440
            HFIENNNTK TTARNAFEEN FMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQS+IPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKL+SRTGHLMKLLSGQQEVKASKIEWDTDQWK ENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLE  KE+PGYGYT KLILALIVTGILTILIIL CLI ICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR 1620


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 1743 bits (4514), Expect = 0.0
 Identities = 856/870 (98%), Positives = 858/870 (98%)

Query: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60
           MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+SW
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360

Query: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780

Query: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
          Length = 947

 Score =  751 bits (1940), Expect = 0.0
 Identities = 393/570 (68%), Positives = 440/570 (77%), Gaps = 32/570 (5%)

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            EL     E P  P +  + Q  +     NP   +D     +      QLL L   + P  
Sbjct: 240  ELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPS- 298

Query: 622  TTEVGHSTPPKRTIVS----PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT--PK 675
            T +   + PP+ ++ S    P + EVT+  P + Q  H +L + TV+P D+  T+T  PK
Sbjct: 299  TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQA-HYNLPKFTVKPADVEVTMTSEPK 357

Query: 676  SMTE---------------VEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
            + TE                EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+ATVQ
Sbjct: 358  NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQ 417

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDR 779
            PLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE  HSTALEKT AP PD+
Sbjct: 418  PLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQ 477

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDE 839
            VQTLHRSLTEVTGPPT+LE +QDSLVQSE        TAPEE KASTSTNICELCTCGDE
Sbjct: 478  VQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCTCGDE 529

Query: 840  MLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILREN 899
             LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLIL EN
Sbjct: 530  TLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSEN 589

Query: 900  NLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQA 959
             LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS GTFQA
Sbjct: 590  YLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQA 649

Query: 960  WHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI 1019
            WHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVELEKLI
Sbjct: 650  WHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLI 709

Query: 1020 LPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKN 1079
            LPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+ HCPEEASVGNPEGAFMK+LQARK 
Sbjct: 710  LPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQ 769

Query: 1080 YTSTELIVEPEEPSDSSGINLSGFGSEQLD 1109
            + ST+L +E E PSDSSGINLSGFG +QL+
Sbjct: 770  HMSTQLTIESEAPSDSSGINLSGFGGDQLE 799



 Score =  479 bits (1233), Expect = e-134
 Identities = 283/539 (52%), Positives = 327/539 (60%), Gaps = 81/539 (15%)

Query: 13  MSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSWSSHSSHFPRESP 72
           MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPP+ WSS SSH P ESP
Sbjct: 1   MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60

Query: 73  HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQD 132
           HAP  PA P DFD+LGPSASS+M A PQE TENL PFL   DSAGE PL PE FLA+ QD
Sbjct: 61  HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120

Query: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
           L DK +P+ERLP     L +D        P  +W                          
Sbjct: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180

Query: 159 --------------------SLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
                               SL EI+GI  QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240

Query: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
           LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E   S Q
Sbjct: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300

Query: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
           QEAPALPPESSMESL  T  NHEV+VQPPGEDQA+Y+LP  TVKPADVEVT+TSEP NET
Sbjct: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360

Query: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP-----VQPSESPR 371
           ES+QAQQE PIQ PEE EPS+T       PP  P E  L  S++ Q       + +  P 
Sbjct: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHP-EVTLPPSDKGQAQHSHLTEATVQPL 419

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGT 431
           ++E S T + T        EV  SP          +   S +PPD  L I  EP+ E+G 
Sbjct: 420 DLELSITTEPTT-------EVKPSP---------TTEETSAQPPDPGLAITPEPTTEIGH 463

Query: 432 SLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
           S   ++           +     +  GPP   ESS+++    VQ ET+ +  +   + N
Sbjct: 464 STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDS---LVQSETAPEEQKASTSTN 519



 Score =  173 bits (438), Expect = 1e-42
 Identities = 89/144 (61%), Positives = 112/144 (77%), Gaps = 1/144 (0%)

Query: 1470 GDQFEIQLTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLS 1529
            GDQ EIQLT+QL+SLIPN +VR+ ++HVIRTLKM+CS  HVQ +CAKL+ RTG LMKLLS
Sbjct: 795  GDQLEIQLTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLS 854

Query: 1530 GQQEVKASKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVT 1589
             QQE KA  +EWDTDQ K  NYINE+ E   ++++KS EL KEVPG  Y +KLI A+ VT
Sbjct: 855  EQQEAKALNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVT 913

Query: 1590 GILTILIILFCLIVICCHRRSLQE 1613
             IL ILII+FCLI +  H+R+ ++
Sbjct: 914  VILIILIIIFCLIEVNSHKRASEK 937



 Score =  116 bits (290), Expect = 2e-25
 Identities = 97/286 (33%), Positives = 124/286 (43%), Gaps = 54/286 (18%)

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
           N  EPP     GPP      E+ G      E   Q+PE + +   S  Q+EA A+  Q  
Sbjct: 244 NADEPP-----GPP------EQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP 292

Query: 507 EEGESSLTHQEAPAQTPE----------FPNVVVAQPP----EHSHLTQATVQPLDLGFT 552
           +E E S T QEAPA  PE            + V  QPP     H +L + TV+P D+  T
Sbjct: 293 QEVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVT 351

Query: 553 ITPESKTEVELSPTMKETPTQPPKKVVPQ---LRV------YQGVTNPTPGQDQAQHPVS 603
           +T E K E E +   +E P QPP++  P    LR       +  VT P   + QAQH   
Sbjct: 352 MTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHL 411

Query: 604 PSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL------------------ 645
              TVQ LDL L+IT EPTTEV  S   + T   P  P + +                  
Sbjct: 412 TEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTR 471

Query: 646 -PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA 690
            PHPDQVQT H  LT  T  P  L  +      +E  P     +T+
Sbjct: 472 APHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTS 517


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  106 bits (265), Expect = 2e-22
 Identities = 182/758 (24%), Positives = 266/758 (35%), Gaps = 101/758 (13%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 148 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 202

Query: 183 EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST      + P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 203 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 258

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 259 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 318

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE 354
                     TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E
Sbjct: 319 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 378

Query: 355 -LSISEQQQPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ 401
               + +  P  P E            +P+E   +  ++ TP  P E    T  P     
Sbjct: 379 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PT 436

Query: 402 THHLASPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND 448
           T    +P+   K             P +   T   EPS    T+      TT  S     
Sbjct: 437 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTT 493

Query: 449 VEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
            EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T 
Sbjct: 494 KEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTP 548

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
           +E   + T + AP  TP+ P     +   P     LT  T + L       P   T  EL
Sbjct: 549 KEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 607

Query: 564 SPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
           +PT  E PT    + P    P+         P P   +   P +P              P
Sbjct: 608 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EP 655

Query: 620 EPTT--EVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
            PTT  E   +TP      + K P  T P  P   +   +     T    D     TPK 
Sbjct: 656 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 715

Query: 677 MTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--T 732
                P     TT   P P  P+ T P + K  A     T     P +L  T T  P  T
Sbjct: 716 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTST 772

Query: 733 TEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETRHSTALEKTTAPRPDRVQTLHRSL 787
           T  KP+PTT +    T+ + P       P PTT ET   T  E +T        T+H+S 
Sbjct: 773 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 832

Query: 788 TEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
            E T P    EP   +L  S        T+  A T PE
Sbjct: 833 DEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 869



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 176/766 (22%), Positives = 264/766 (34%), Gaps = 130/766 (16%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 253 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 311

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 312 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 371

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 372 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 545

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 546 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 603

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 658

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 659 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 718

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLL---------------DLGLTIT----------PE 620
                P P   +   P +P  T                   +L  T T          P 
Sbjct: 719 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 778

Query: 621 PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFT---ITPK 675
           PTT  E   +TP +    +PK P  T P      T        T +P  +  +    TP+
Sbjct: 779 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 838

Query: 676 SMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEV 735
              E  P  AL  +   PG P    P + K +         T +    E  + T P T  
Sbjct: 839 LSAEPTPK-ALENSPKEPGVPTTKTPAATKPEMT------TTAKDKTTERDLRTTPETTT 891

Query: 736 KPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE---------KTTAPRPDRVQTLHRS 786
                T+ET+T       + I   TT+   +T  +         KTT   P +V T  ++
Sbjct: 892 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP-KVTTTKKT 950

Query: 787 L--TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKASTST 828
           +  TE+   P E    +D    S++ T    K   AP   K  TST
Sbjct: 951 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP---KKPTST 993



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 327  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 375

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 376  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 421

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 422  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 479

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 480  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 540  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 595

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 596  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 655

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 656  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 714

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 715  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 775  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 825

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 826  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 871

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 872  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 921

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 922  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 979

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 980  PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1029

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 1030 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 167/760 (21%), Positives = 257/760 (33%), Gaps = 116/760 (15%)

Query: 144 PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT---------------LQNEYSSTD 188
           P SP   KK P    +   I   T++   P ++K+T                +N+ SS+ 
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 128

Query: 189 TPYPGSLPPELRVKSDEPPGPSEQV--------GPSQFHLEPETQNPETLEDIQS----- 235
           +    S     ++KS +    + ++               +  T  P  +++  S     
Sbjct: 129 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 188

Query: 236 ---------SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES--SMESLTLPNHEVSVQP 284
                    S+ Q    +  P++   +P + +   P+LPP S  S E+    N E +V+ 
Sbjct: 189 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR---PSLPPNSDTSKETSLTVNKETTVET 245

Query: 285 PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQ---------------ETPIQF 329
                      N        E T +++ T   E + A+                ET  + 
Sbjct: 246 KETTTT-----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 300

Query: 330 PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE-SPREVESSPT--QQETPGQP 386
           P    P       P EP     +     + +  P  P E +P   +S+PT  ++  P   
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360

Query: 387 PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG 446
            E    T   P    T   A  +    P   +      P     T+      TT    + 
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 420

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
              + PA     P   P + +E  P      T+ + P P   + P+PT  +  A  P T 
Sbjct: 421 TTPKEPAPTTKEP--APTTPKEPAP------TAPKKPAPTTPKEPAPTTPKEPA--PTTT 470

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
           +E   +   + AP  T   P       P  +     T +      T  P   T  E +PT
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 530

Query: 567 --MKETPTQP--PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT-ITPE- 620
              K  PT P  P    P+         P P   +   P +P  T       LT  TPE 
Sbjct: 531 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 590

Query: 621 --PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
             PTT  +   +TP +    +P+ P  T P      T  +       +P        P +
Sbjct: 591 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP-------APTT 643

Query: 677 MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA-----QHSHLTQATVQPLDLELTITTKP 731
             E  P+T      P P  P+ T P + KG A     + +  T     P +L  T T +P
Sbjct: 644 PKEPAPTT---PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 700

Query: 732 TTEV--KPSPTTEE--TSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSL 787
           T+    KP+PTT +    T P +      P PTT    +    K TAP      TL    
Sbjct: 701 TSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAP-----TTLKEPA 749

Query: 788 TEVTGPPTELEPAQDSLVQSESYTQNK-ALTAPEEHKAST 826
                 P   E A  +     S T +K A T P+E   +T
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 789



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 128/617 (20%), Positives = 220/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 124

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 171

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 172 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 231

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 232 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 395

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 396 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 447

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 448 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 497

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT  + +    K  AP   +  
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 552 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 609 PTTPEEPTPTTPEEPAP 625



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 811  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 871  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 919


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  106 bits (265), Expect = 2e-22
 Identities = 182/758 (24%), Positives = 266/758 (35%), Gaps = 101/758 (13%)

Query: 128 ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITR-----QLSTPQSQKQTLQN 182
           A+ ++L+ KL  ++       + KK P  +  + +  G        +++TP +   T Q+
Sbjct: 189 AANRELQKKLKVKDN---KKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTS--TTQH 243

Query: 183 EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
              ST      + P  +  +   PP  S+    +   +  ET   ET E   ++      
Sbjct: 244 NKVSTSPKITTAKP--INPRPSLPPN-SDTSKETSLTVNKET-TVETKETTTTNKQTSTD 299

Query: 243 PAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA 302
             +     +E  S  +  A  L P S + +   P  E + + P         P    +PA
Sbjct: 300 GKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA 359

Query: 303 DVE------VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE 354
                     TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E
Sbjct: 360 STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKE 419

Query: 355 -LSISEQQQPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ 401
               + +  P  P E            +P+E   +  ++ TP  P E    T  P     
Sbjct: 420 PAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PT 477

Query: 402 THHLASPSVSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND 448
           T    +P+   K             P +   T   EPS    T+      TT  S     
Sbjct: 478 TPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTT 534

Query: 449 VEPPAIQHGGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
            EP        P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T 
Sbjct: 535 KEPAPTTTKSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTP 589

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
           +E   + T + AP  TP+ P     +   P     LT  T + L       P   T  EL
Sbjct: 590 KEPAPTTTKKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEEL 648

Query: 564 SPTMKETPT----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
           +PT  E PT    + P    P+         P P   +   P +P              P
Sbjct: 649 APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EP 696

Query: 620 EPTT--EVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
            PTT  E   +TP      + K P  T P  P   +   +     T    D     TPK 
Sbjct: 697 APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKG 756

Query: 677 MTEVEPSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--T 732
                P     TT   P P  P+ T P + K  A     T     P +L  T T  P  T
Sbjct: 757 TAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTST 813

Query: 733 TEVKPSPTTEE----TSTQPPDLGLAIIPEPTT-ETRHSTALEKTTAPRPDRVQTLHRSL 787
           T  KP+PTT +    T+ + P       P PTT ET   T  E +T        T+H+S 
Sbjct: 814 TSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSP 873

Query: 788 TEVTGPPTELEPAQDSLVQSES-----YTQNKALTAPE 820
            E T P    EP   +L  S        T+  A T PE
Sbjct: 874 DEST-PELSAEPTPKALENSPKEPGVPTTKTPAATKPE 910



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 176/766 (22%), Positives = 264/766 (34%), Gaps = 130/766 (16%)

Query: 168  RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
            +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 294  KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 352

Query: 228  ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
             T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 353  TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 412

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
            +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 413  APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470

Query: 322  QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
             +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 471  TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530

Query: 377  PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
            PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 531  PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 586

Query: 428  EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
               T       TT+        EP P       P             L P + E+  P  
Sbjct: 587  T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 644

Query: 474  VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
             ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 645  PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 699

Query: 532  QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
             P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 700  TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 759

Query: 586  QGVTNPTPGQDQAQHPVSPSVTVQLL---------------DLGLTIT----------PE 620
                 P P   +   P +P  T                   +L  T T          P 
Sbjct: 760  TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 819

Query: 621  PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFT---ITPK 675
            PTT  E   +TP +    +PK P  T P      T        T +P  +  +    TP+
Sbjct: 820  PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 879

Query: 676  SMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEV 735
               E  P  AL  +   PG P    P + K +         T +    E  + T P T  
Sbjct: 880  LSAEPTPK-ALENSPKEPGVPTTKTPAATKPEMT------TTAKDKTTERDLRTTPETTT 932

Query: 736  KPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE---------KTTAPRPDRVQTLHRS 786
                 T+ET+T       + I   TT+   +T  +         KTT   P +V T  ++
Sbjct: 933  AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP-KVTTTKKT 991

Query: 787  L--TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKASTST 828
            +  TE+   P E    +D    S++ T    K   AP   K  TST
Sbjct: 992  ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP---KKPTST 1034



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 368  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 416

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 417  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 462

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 463  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 520

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 521  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 581  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 636

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 637  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 696

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 697  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 755

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 756  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 816  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 866

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 867  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 912

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 913  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 962

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 963  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 1020

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 1021 PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 1070

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 1071 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 167/760 (21%), Positives = 257/760 (33%), Gaps = 116/760 (15%)

Query: 144 PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT---------------LQNEYSSTD 188
           P SP   KK P    +   I   T++   P ++K+T                +N+ SS+ 
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSS 169

Query: 189 TPYPGSLPPELRVKSDEPPGPSEQV--------GPSQFHLEPETQNPETLEDIQS----- 235
           +    S     ++KS +    + ++               +  T  P  +++  S     
Sbjct: 170 SSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNG 229

Query: 236 ---------SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES--SMESLTLPNHEVSVQP 284
                    S+ Q    +  P++   +P + +   P+LPP S  S E+    N E +V+ 
Sbjct: 230 DFKVTTPDTSTTQHNKVSTSPKITTAKPINPR---PSLPPNSDTSKETSLTVNKETTVET 286

Query: 285 PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQ---------------ETPIQF 329
                      N        E T +++ T   E + A+                ET  + 
Sbjct: 287 KETTTT-----NKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKG 341

Query: 330 PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE-SPREVESSPT--QQETPGQP 386
           P    P       P EP     +     + +  P  P E +P   +S+PT  ++  P   
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401

Query: 387 PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG 446
            E    T   P    T   A  +    P   +      P     T+      TT    + 
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTP 461

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
              + PA     P   P + +E  P      T+ + P P   + P+PT  +  A  P T 
Sbjct: 462 TTPKEPAPTTKEP--APTTPKEPAP------TAPKKPAPTTPKEPAPTTPKEPA--PTTT 511

Query: 507 EEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
           +E   +   + AP  T   P       P  +     T +      T  P   T  E +PT
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPT 571

Query: 567 --MKETPTQP--PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT-ITPE- 620
              K  PT P  P    P+         P P   +   P +P  T       LT  TPE 
Sbjct: 572 TPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEK 631

Query: 621 --PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKS 676
             PTT  +   +TP +    +P+ P  T P      T  +       +P        P +
Sbjct: 632 LAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP-------APTT 684

Query: 677 MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQA-----QHSHLTQATVQPLDLELTITTKP 731
             E  P+T      P P  P+ T P + KG A     + +  T     P +L  T T +P
Sbjct: 685 PKEPAPTT---PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEP 741

Query: 732 TTEV--KPSPTTEE--TSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSL 787
           T+    KP+PTT +    T P +      P PTT    +    K TAP      TL    
Sbjct: 742 TSTTCDKPAPTTPKGTAPTTPKE------PAPTTPKEPAPTTPKGTAP-----TTLKEPA 790

Query: 788 TEVTGPPTELEPAQDSLVQSESYTQNK-ALTAPEEHKAST 826
                 P   E A  +     S T +K A T P+E   +T
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTT 830



 Score = 72.0 bits (175), Expect = 5e-12
 Identities = 128/617 (20%), Positives = 220/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 165

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 212

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 213 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 272

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 273 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 436

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 437 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 488

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 489 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 538

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT  + +    K  AP   +  
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 593 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 650 PTTPEEPTPTTPEEPAP 666



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 852  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 912  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 960


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 351

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 409 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 463

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 464 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 570

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 746

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPE 776



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 176/766 (22%), Positives = 264/766 (34%), Gaps = 130/766 (16%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 218

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 219 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 278

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 279 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 452

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 453 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 510

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 565

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 566 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 625

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLL---------------DLGLTIT----------PE 620
                P P   +   P +P  T                   +L  T T          P 
Sbjct: 626 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 685

Query: 621 PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFT---ITPK 675
           PTT  E   +TP +    +PK P  T P      T        T +P  +  +    TP+
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 745

Query: 676 SMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEV 735
              E  P  AL  +   PG P    P + K +         T +    E  + T P T  
Sbjct: 746 LSAEPTPK-ALENSPKEPGVPTTKTPAATKPEMT------TTAKDKTTERDLRTTPETTT 798

Query: 736 KPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE---------KTTAPRPDRVQTLHRS 786
                T+ET+T       + I   TT+   +T  +         KTT   P +V T  ++
Sbjct: 799 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP-KVTTTKKT 857

Query: 787 L--TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKASTST 828
           +  TE+   P E    +D    S++ T    K   AP   K  TST
Sbjct: 858 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP---KKPTST 900



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68  PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
           P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 234 PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 282

Query: 128 ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
             +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 328

Query: 180 LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
              E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 386

Query: 240 QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
           + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 285 ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
              P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 447 PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 502

Query: 338 TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
            ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 503 PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 562

Query: 384 GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                      +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 563 APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 621

Query: 444 GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
           G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 622 GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 489 ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
           + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 682 DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 732

Query: 549 LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 733 TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 778

Query: 608 VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                   T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 779 --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 828

Query: 668 LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                   F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 829 TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 886

Query: 718 VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRP 777
            Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 887 PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 936

Query: 778 DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             +QT  R          E+ P  +    +E  T +  L
Sbjct: 937 AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 96/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 236

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 237 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 293

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 294 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 347 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 395

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETRHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT  + +    K 
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 449

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 450 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 506

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAP 532



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 159

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 220 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 271

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 718  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 778  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 826


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 392

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 450 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 504

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 505 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 611

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 787

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPE 817



 Score = 98.6 bits (244), Expect = 5e-20
 Identities = 176/766 (22%), Positives = 264/766 (34%), Gaps = 130/766 (16%)

Query: 168 RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
           +Q ST   +K T   E  S +      L P  +V + +P   +E          P+   P
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA-KPTPKAETTTKGPALTTPKEPTP 259

Query: 228 ETLEDIQSSSLQQEAPAQLPQL-------------------LEEEPSSMQQEAPALPPES 268
            T ++  S++ ++  P  +                       E  P++ ++ AP  P E 
Sbjct: 260 TTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEP 319

Query: 269 SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPA-----DVEVTITSEPTNET--ESSQA 321
           +  +   P    +   P   +     P    KPA     +   T   EPT  T  E +  
Sbjct: 320 APTTTKEPAPTTTKSAPTTPKE--PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPSE-SPREVESS 376
            +E     P+E  P+A ++ AP  P    P  P E   + +++  P  P E +P   +S+
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437

Query: 377 PTQQETPGQ---------PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
           PT  + P           P E    T   P    T    +P+   KP     T   EP+ 
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAP-TTPKEPAPTTPKKPAP---TTPKEPAP 493

Query: 428 EVGTSLVHQEATTRLSGSGNDVEP-PAIQHGGPP-------------LLPESSEEAGPLA 473
              T       TT+        EP P       P             L P + E+  P  
Sbjct: 494 T--TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTT 551

Query: 474 VQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
            ++   T+ + P P   E P+PT  +AAA  P T +E   +   + AP  TP+ P     
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPAPTTPKEPAPT-TPKEP--APT 606

Query: 532 QPPEHSHLTQATVQPLDLG--FTITPESKTEVELSPTMKETPTQP----PKKVVPQLRVY 585
            P E +  T     P  L      TP+     EL+PT  + PT      P    P+    
Sbjct: 607 TPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAP 666

Query: 586 QGVTNPTPGQDQAQHPVSPSVTVQLL---------------DLGLTIT----------PE 620
                P P   +   P +P  T                   +L  T T          P 
Sbjct: 667 TTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPA 726

Query: 621 PTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFT---ITPK 675
           PTT  E   +TP +    +PK P  T P      T        T +P  +  +    TP+
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPE 786

Query: 676 SMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEV 735
              E  P  AL  +   PG P    P + K +         T +    E  + T P T  
Sbjct: 787 LSAEPTPK-ALENSPKEPGVPTTKTPAATKPEMT------TTAKDKTTERDLRTTPETTT 839

Query: 736 KPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE---------KTTAPRPDRVQTLHRS 786
                T+ET+T       + I   TT+   +T  +         KTT   P +V T  ++
Sbjct: 840 AAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAP-KVTTTKKT 898

Query: 787 L--TEVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKASTST 828
           +  TE+   P E    +D    S++ T    K   AP   K  TST
Sbjct: 899 ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAP---KKPTST 941



 Score = 96.3 bits (238), Expect = 2e-19
 Identities = 181/819 (22%), Positives = 275/819 (33%), Gaps = 147/819 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P     APT P +P       P+ +   P  P+E          T + A   P EP    
Sbjct: 275  PTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT-----TKEPAPTTPKEPAPTT 323

Query: 128  ASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
              +       S    P+E  P +PKK      K+PA               +TP+    T
Sbjct: 324  TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP--------------TTPKEPTPT 369

Query: 180  LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
               E + T      + P E    + + P P+    P+     P+   P T ++   ++ +
Sbjct: 370  TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPKEPAPTTTKEPSPTTPK 427

Query: 240  QEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP------------ 284
            + AP      P   +E   +  + AP  P E S  +   P      +P            
Sbjct: 428  EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 285  ---PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQAQQETPIQFPEEVEPSA 337
               P         P  T KPA    T   EP      ET  +  ++ TP   PE++ P+ 
Sbjct: 488  PKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTPKKLTPTT-PEKLAPTT 543

Query: 338  TQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV------ESSPTQQETP 383
             ++ AP  P    P  P E   +  E+  P  P      +P+E       E +PT  + P
Sbjct: 544  PEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP 603

Query: 384  GQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLS 443
                       +P G   T  L  P+ +         +A   + E  ++   + A T   
Sbjct: 604  APTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPK 662

Query: 444  GSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-------TSFQSPEPINN 488
            G+      EP P       P  P+ +     +E  P   ++        T+ + P    +
Sbjct: 663  GTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLD 548
            + P+PT  +  A  P T +E   +   + AP  TPE P      PP  S ++  T     
Sbjct: 723  DKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------PPTTSEVSTPTTTKEP 773

Query: 549  LGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVT 607
                 +P+  T E+   PT K     P +  VP        T  TP   +      P +T
Sbjct: 774  TTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTKTPAATK------PEMT 819

Query: 608  VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    T   + TTE    T P+ T  +PK  + T    ++  T  S +T  T Q   
Sbjct: 820  --------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK--TTESKITATTTQVTS 869

Query: 668  LG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                    F IT    T + P        +TT      PE T  P D+  A +S  T   
Sbjct: 870  TTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDR--ATNSKATTPK 927

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRP 777
             Q          KPT   K   +T++  T P        P P   T     L  T+    
Sbjct: 928  PQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAE 977

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
              +QT  R          E+ P  +    +E  T +  L
Sbjct: 978  AMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 96/386 (24%), Positives = 139/386 (36%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 277

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 278 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 334

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 335 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 388 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 436

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETRHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT  + +    K 
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 490

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 491 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 547

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAP 573



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 200

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 261 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 312

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 759  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 819  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 867


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 95.1 bits (235), Expect = 5e-19
 Identities = 184/793 (23%), Positives = 266/793 (33%), Gaps = 123/793 (15%)

Query: 52   NPLGPP--DSWSSHSSHFPRESPHAPTLPADPW-DFDHLG-PSASSEMPAPPQESTENLV 107
            +PL PP  +S +S      R SP    LPA P  +  HL  P   S +  PP+ES  +  
Sbjct: 447  SPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSPP 506

Query: 108  PFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQ-ERLPVSPKKLKKDPAQRWSLAEIIGI 166
            P    +    E PL P +       L+  LSP  E  P+SP   ++ P            
Sbjct: 507  PESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESP------------ 553

Query: 167  TRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
               LS P  +               P S PPE    S  P        P +  + P  + 
Sbjct: 554  ---LSPPPEE--------------LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
                   + S L            EE P S   EA  L P      ++ P  E  + PP 
Sbjct: 597  SRLFPPFEESPLSPPP--------EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIE 345
            E      LP ++      E +  S P  E+ +S   + + +  P E  P S   +++P  
Sbjct: 649  EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708

Query: 346  PPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP-PEHHEVTVSPPGHHQTHH 404
            P  PP +  +S+  ++ P+ P   P E +  P  +     P PE   ++  P   H +  
Sbjct: 709  P--PPEDSLMSLPLEESPLLP--LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQ 764

Query: 405  LASPSVSVKPPDVQLTIAAE-----PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP 459
               P +S +P +  L    E     P AE G  L  Q     LS    +          P
Sbjct: 765  AEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEE----------P 813

Query: 460  PLLPESSEEA-GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
             L P   E    P   +   S QS EP  +  P  +      E P  +   E      E 
Sbjct: 814  HLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP---PEE 870

Query: 519  PAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKV 578
            P Q P    + +  PP    L+    +P             E  LSP  +E P  P  + 
Sbjct: 871  PGQCPAPEELPLFPPPGEPSLSPLLGEP-------ALSEPGEPPLSPLPEELPLSPSGE- 922

Query: 579  VPQLRVYQGVTNPTPGQDQAQHPVSPSVTV----QLLDLGLTITP-----EPTTEVGHST 629
             P L       +P P       P+SP +T      L  LG    P     +   E   + 
Sbjct: 923  -PSLSPQLMPPDPLP------PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAA 975

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP------- 682
            P   T +SP  PE     P+ V           + P   G  + P S   +EP       
Sbjct: 976  PILETPISPP-PEANCTDPEPVPPM--------ILPPSPGSPVGPASPILMEPLPPQCSP 1026

Query: 683  ---STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
                + +   +PP       LP S                  +L    T K +    P+ 
Sbjct: 1027 LLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPAL 1086

Query: 740  TTEETSTQPPDLG--LAIIPEPTTETRHSTALEKTTAP---------RPDRVQTLHRSLT 788
                TS  P  +G      P P       + L + TAP         +P+  QT     +
Sbjct: 1087 EPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLAS 1146

Query: 789  EVTGPPTELEPAQ 801
            E+ G P  L+P +
Sbjct: 1147 ELKGSPVLLDPEE 1159



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 152/613 (24%), Positives = 233/613 (38%), Gaps = 93/613 (15%)

Query: 183 EYSSTDTPYPGSL-------PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
           E   T T  P +L       P    V S +P  P    GP Q   +P  +    LE    
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP----GPLQCEAKPLGKAGVQLEPQLE 431

Query: 236 SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS-VQPPGEDQAYYHL 294
           + L +E P   P           +E+P  PP    ES T P  E S + PP E+     L
Sbjct: 432 APLNEEMPLLPPP----------EESPLSPPPE--ESPTSPPPEASRLSPPPEELPASPL 479

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-----EPPVP 349
           P         E    S P  E+  S   +E+P+  P E  P +  +E+P+      PP P
Sbjct: 480 P---------EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530

Query: 350 PMEHELSISEQQQPVQP--SESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +E  LS   +  P+ P   ESP     SP  +E P  PP        PP   ++     
Sbjct: 531 ALETPLSPPPEASPLSPPFEESP----LSPPPEELPTSPPPEASRLSPPP--EESPMSPP 584

Query: 408 PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
           P  S   P  + +    P  E   S   +E+        + + PP       P+ P   E
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP---EDSPMSPPPEE 641

Query: 468 EAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA------EEGESSLTHQEAPAQ 521
              P++   E S  SP P+ +    P ++   +  P+ +      E    S   +++P  
Sbjct: 642 --SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699

Query: 522 TPEFPNVVVAQPPEHS----HLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKK 577
            P   +   + PPE S     L ++ + PL     + P S+    LSP  +E P   P+ 
Sbjct: 700 PPP-EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPRPEE-PHLSPRP 756

Query: 578 VVPQLRVYQGVTNPTPGQDQ---AQHPVSPSVTVQLLDLGLTITPE-----PTTEVGHST 629
             P L       + +P  ++      P  P ++ Q     L+  PE     P TE  H +
Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816

Query: 630 P-PKRTIVSPKHPEVTL-PHPDQ----VQTQHSHLTRATVQPLDLGFTITPKSMTEVE-- 681
           P P+   +SP+  E  L P  ++     + + SHL+    +P      ++P+     E  
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-----PLSPRPEKPPEEP 871

Query: 682 ---PSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPS 738
              P+   +   PPPG P  +L P   G+   S   +  + PL  EL ++  P+ E   S
Sbjct: 872 GQCPAPEELPLFPPPGEP--SLSPL-LGEPALSEPGEPPLSPLPEELPLS--PSGEPSLS 926

Query: 739 PTTEETSTQPPDL 751
           P        PP L
Sbjct: 927 PQLMPPDPLPPPL 939



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 99/427 (23%), Positives = 149/427 (34%), Gaps = 78/427 (18%)

Query: 356 SISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTV--SPPGHHQTHHLASPSVSVK 413
           S++EQ  PV    SP      P   +TP   P+   V     P G H T      S+  K
Sbjct: 360 SVAEQHTPVCSRFSP------PEPGDTPTDEPDALYVACQGQPKGGHVT------SMQPK 407

Query: 414 PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA 473
            P   L   A+P  + G  L  Q            +E P  +    PLLP   E   PL+
Sbjct: 408 EPG-PLQCEAKPLGKAGVQLEPQ------------LEAPLNEE--MPLLPPPEE--SPLS 450

Query: 474 VQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP--EFPNVVVA 531
              E S  SP P  +    P ++  A+  P+       S   +E+P   P  E P   ++
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLEESPLSPPPEESP---LS 504

Query: 532 QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PPE S  +     PL       P    E  LSP  + +P  PP +  P         +P
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP--------LSP 556

Query: 592 TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            P     + P SP      L                S PP+ + +SP   E  +  P + 
Sbjct: 557 PP----EELPTSPPPEASRL----------------SPPPEESPMSPPPEESPMSPPPEA 596

Query: 652 QTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHS 711
                    + + P        P   + + P       +PPP    ++ PP +   +   
Sbjct: 597 SRLFPPFEESPLSP--------PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 712 HLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEK 771
            +++ +  P+   L   + P  E   SP  EE+ T PP     + P P          + 
Sbjct: 649 EVSRLSPLPVVSRL---SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705

Query: 772 TTAPRPD 778
             +P P+
Sbjct: 706 PASPPPE 712



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 140/674 (20%), Positives = 216/674 (32%), Gaps = 109/674 (16%)

Query: 87   LGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LEPEQFLASQQDLKDKLSPQ---ER 142
            LGP     MP  P      LV  L      G Q  L P Q    QQ     L PQ    +
Sbjct: 3769 LGPKPQGLMP--PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQ 3826

Query: 143  LPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVK 202
            + ++  ++   P        ++G   +L T Q Q+Q  Q++   +       L   L   
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMG--HRLVTAQQQQQQQQHQQQGSMAGL-SHLQQSLMSH 3883

Query: 203  SDEPPGPSEQVGP---------------------SQFHLEPETQNPETLEDIQSSSLQQE 241
            S +P   ++ +G                       Q   + + Q  +  +  Q   LQQ+
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 242  APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHL--PNITV 299
               QL Q  ++     QQ+      +   + + L N   ++  P + Q       P +  
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003

Query: 300  KPAD-VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-------EPPVPPM 351
            KP           PT      +     P    E  E  +T Q  P+            P 
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPG 4063

Query: 352  EHELSISEQQQPV----QPSESPREVESSPTQQETPGQPPEHHEV--TVSPPGHHQTHHL 405
            E + S+S   Q +    QP   P  ++  P  +  PGQ  +   +  T     H Q    
Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLR-LPGQQQQQVSLLHTAGGGSHGQLGSG 4122

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND-VEPPAIQHGGP----- 459
            +S   S  P      + A+PS  +G        T  L G     +E P   + GP     
Sbjct: 4123 SSSEASSVP-----HLLAQPSVSLGDQ--PGSMTQNLLGPQQPMLERPMQNNTGPQPPKP 4175

Query: 460  -PLLPESS--------EEAGPLAVQQETSFQSPEPINNENPSPTQQEAA---AEHPQTAE 507
             P+L               G L  Q +        + + +P   QQ  A       Q ++
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235

Query: 508  EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM 567
                +  +QE   QT     ++  QP         T    +LG    P+    +   P  
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295

Query: 568  KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH 627
              T         P L    G  +PTP     Q P  PS   QL        P P++++  
Sbjct: 4296 LSTG--------PVL----GPVHPTPPPSSPQEPKRPS---QL--------PSPSSQL-- 4330

Query: 628  STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               P    + P HP    P    ++     ++ A  Q  D   T+  K +   +P   L 
Sbjct: 4331 ---PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD---TLFSKGLGPWDPPDNLA 4384

Query: 688  TTAPP------PGH 695
             T  P      PGH
Sbjct: 4385 ETQKPEQSSLVPGH 4398



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 175/803 (21%), Positives = 249/803 (31%), Gaps = 138/803 (17%)

Query: 81   PWDFDHLGPSASSEMPAPPQESTENLVPFLDTW----------DSAGEQPLEPEQFLASQ 130
            P +F    P      P+ P    +   P LD              A E  L P  F  S+
Sbjct: 2223 PGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESR 2282

Query: 131  QDLKDKLSPQERLPVS-----PKKLK--KDPAQRWSLAEIIGITRQLSTPQSQKQTLQNE 183
            + L+ K   +E L  S     P  L     P+    L  +     +L TP   K  L   
Sbjct: 2283 KALEVK---KEELGASSPSYGPPNLGFVDSPSSGTHLGGL-----ELKTPDVFKAPLTPR 2334

Query: 184  YSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAP 243
             S  +   PG     L ++  EPP P++ + PS          P +  DI       +  
Sbjct: 2335 ASQVEPQSPG-----LGLRPQEPP-PAQALAPS----------PPSHPDIFRPGSYTDPY 2378

Query: 244  AQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPAD 303
            AQ P     +P    +   ALPP S      LP+   S  P            +T +P  
Sbjct: 2379 AQPPLTPRPQPPP-PESCCALPPRS------LPSDPFSRVPASPQSQSSSQSPLTPRPLS 2431

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS----- 358
             E    S  T   +S       P +      P +    AP+  P  P   E++       
Sbjct: 2432 AEAFCPSPVTPRFQSPDPYSRPPSR------PQSRDPFAPLHKPPRPQPPEVAFKAGSLA 2485

Query: 359  -------------------EQQQPVQPSESPREVES----------SPTQQETP---GQP 386
                               E    V   + P  V S          SP +   P   G+P
Sbjct: 2486 HTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEP 2545

Query: 387  PEHHEVTVS--PPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
                 V     PP H    H        KP     T+A       G+ L     +T  S 
Sbjct: 2546 SLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESY 2605

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHP 503
              + + PP++    PP  P+ S         Q +   SP E   +         A AE P
Sbjct: 2606 GLSPLRPPSVL---PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELP 2662

Query: 504  QTAEEGESSL--THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
             T + G S L  T  E   Q      +++ Q  + + L Q           + P      
Sbjct: 2663 GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGA 2722

Query: 562  E-LSPTMK-----ETP---TQPPKKVV--PQLRVYQGVTNP--TPGQDQAQHPVSPSVTV 608
            E  SP  +     +TP   TQ    +V  P  ++   +  P   P  D+   P  P  T 
Sbjct: 2723 EPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRP-PPPATP 2781

Query: 609  QLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ--PL 666
              +D+           VG S    +   +P    + L    Q   Q    T AT     +
Sbjct: 2782 SSMDV------NSRQLVGGSQAFYQR--APYPGSLPLQQQQQQLWQQQQATAATSMRFAM 2833

Query: 667  DLGFTITP----KSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLD 722
               F  TP           P   + T  P PG P     P   G AQ   L     + L 
Sbjct: 2834 SARFPSTPGPELGRQALGSPLAGISTRLPGPGEP----VPGPAGPAQFIELRHNVQKGLG 2889

Query: 723  LELTITTKPTTEVKPS--PTTEETSTQPPD--LGLAI--IPEPTTETRHSTALEKTTAPR 776
               T         +P   P +E+     P+   GLA+  +P        +  L  +  P 
Sbjct: 2890 PGGTPFPGQGPPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPT 2949

Query: 777  P-DRVQTLHRSLTEVTGPPTELE 798
            P  +  TL   L  V  PP+  E
Sbjct: 2950 PHTKGPTLPTGLELVNRPPSSTE 2972



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 70/286 (24%), Positives = 100/286 (34%), Gaps = 36/286 (12%)

Query: 503  PQTAEEGESSLTHQEAPAQT--PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            PQ   +  S      APA    P FP      PP  S  T A  QP  LG +  P +   
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-TGAPAQPPMLGASSRPGAGQP 2223

Query: 561  VELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             E   T   TP   P    P L+         P  D    P SP V        L ++P 
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNLAVPESPGVGGGKASEPL-LSPP 2276

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS--HLTRATVQPLDL-GFTITPKSM 677
            P  E   +   K+  +    P    P+   V +  S  HL    ++  D+    +TP++ 
Sbjct: 2277 PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA- 2335

Query: 678  TEVEPSTALMTTAP------------PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL 725
            ++VEP +  +   P            PP HP++  P S         LT     P     
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 726  ------TITTKPTTEVKPSPTTEETSTQP----PDLGLAIIPEPTT 761
                  ++ + P + V  SP ++ +S  P    P    A  P P T
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441



 Score = 39.3 bits (90), Expect = 0.033
 Identities = 114/611 (18%), Positives = 208/611 (34%), Gaps = 112/611 (18%)

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ----EAPALPPESSMESLTLP 276
            + + Q  +  +  Q S++   +P+Q P+LL + P  +      + P  PP      L L 
Sbjct: 3599 QQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658

Query: 277  NHEVSV--QPPG--------EDQAYYHL---------------PNITVKPADVEVTITSE 311
               +++  QP G        + Q   H                 N+ ++    +  +  E
Sbjct: 3659 PGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718

Query: 312  P-----------TNETESSQAQQETPIQFPEEVEPSATQQEAP-------IEPP----VP 349
                          + +  Q QQ+       +V     QQ+ P       + P     +P
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMP 3778

Query: 350  PMEHELSISEQQQPVQPSESPR----EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHL 405
            P  H+  + +Q  P QP + P+      + +  QQ+ PG         + P G H+   +
Sbjct: 3779 PSSHQGLLVQQLSP-QPPQGPQGMLGPAQVAVLQQQHPG--------ALGPQGPHRQVLM 3829

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG---NDVEPPAIQHGGPPLL 462
                V   P   Q          V      Q+   +  GS    + ++   + H G P L
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889

Query: 463  PESSEEAGPL-AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQ 521
              S++  G L  +QQ+   Q  + +  +     QQ+   +  Q  ++ +     Q+   Q
Sbjct: 3890 --SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGF------TITP--ESKTEVELSPTMKETPTQ 573
              +    +  Q  +     Q   Q   +G        ++P  + + +V L P M   P Q
Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQ 4007

Query: 574  ---PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH--- 627
                P  + P L +            + Q+ V P+V+ +        T  P+T  G    
Sbjct: 4008 HFSSPGALGPTLLL----------TGKEQNTVDPAVSSE-------ATEGPSTHQGGPLA 4050

Query: 628  -STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP--KSMTEVEPST 684
              T P+     P   + +L    Q+      L +   QP      + P  +   + +   
Sbjct: 4051 IGTTPESMATEPGEVKPSLSGDSQLL-----LVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105

Query: 685  ALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK---PTTEVKPSPTT 741
            +L+ TA    H ++    S +  +    L Q +V   D   ++T     P   +   P  
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165

Query: 742  EETSTQPPDLG 752
              T  QPP  G
Sbjct: 4166 NNTGPQPPKPG 4176



 Score = 38.9 bits (89), Expect = 0.043
 Identities = 125/552 (22%), Positives = 186/552 (33%), Gaps = 131/552 (23%)

Query: 187  TDTPYPG-----SLPPELRVKSDEPPGPSEQVGPSQFHLEP------ETQNPETLEDIQS 235
            T  PYP      + PP L   S   PG  +   P +FH  P      +   P+     + 
Sbjct: 2195 TYPPYPSPTGAPAQPPMLGASSR--PGAGQ---PGEFHTTPPGTPRHQPSTPDPFLKPRC 2249

Query: 236  SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLP 295
             SL   A  + P +   + S      P  P   S ++L +   E+    P      Y  P
Sbjct: 2250 PSLDNLAVPESPGVGGGKASEPLLSPP--PFGESRKALEVKKEELGASSPS-----YGPP 2302

Query: 296  NITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHEL 355
            N+              P++ T     + +TP  F   + P A+Q    +EP  P +    
Sbjct: 2303 NLG---------FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQ----VEPQSPGLG--- 2346

Query: 356  SISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKP- 414
                    ++P E P      P Q   P  PP H ++    PG + T   A P ++ +P 
Sbjct: 2347 --------LRPQEPP------PAQALAPS-PPSHPDIF--RPGSY-TDPYAQPPLTPRPQ 2388

Query: 415  -PDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA 473
             P  +   A  P +          A+ +   S      P          P S+E   P  
Sbjct: 2389 PPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPR---------PLSAEAFCPSP 2439

Query: 474  VQQETSFQSPEPINNENPSPTQQEAAAE-----HPQTAEEG--ESSLTHQEAPAQTPEFP 526
            V     FQSP+P +     P  ++  A       PQ  E      SL H    A    FP
Sbjct: 2440 VTPR--FQSPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGG--FP 2495

Query: 527  NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
              + A P    H    + QP +  F  +P +   V        TP+ P +   PQ     
Sbjct: 2496 AALPAGPAGELHAKVPSGQPPN--FVRSPGTGAFVG-------TPS-PMRFTFPQ----- 2540

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP 646
                   G+   + PV                P+P        PP   I S   P  TL 
Sbjct: 2541 -----AVGEPSLKPPV----------------PQP------GLPPPHGINSHFGPGPTLG 2573

Query: 647  HPDQ----VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPP 702
             P      V T + H + + + P   G T     ++ + P + L     PP  P+ +LP 
Sbjct: 2574 KPQSTNYTVATGNFHPSGSPLGPSS-GSTGESYGLSPLRPPSVL-----PPPAPDGSLPY 2627

Query: 703  SDKGQAQHSHLT 714
               G +Q S +T
Sbjct: 2628 LSHGASQRSGIT 2639



 Score = 35.4 bits (80), Expect = 0.48
 Identities = 120/551 (21%), Positives = 191/551 (34%), Gaps = 124/551 (22%)

Query: 114  DSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTP 173
            D+A  +PL P+         K      +RL  S KKL+K+   R S A +  + ++LS  
Sbjct: 4511 DAAARKPLTPKP--------KRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL 4562

Query: 174  QSQKQTLQNEYSSTDTPYPGSLP----PELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
               +  +   + S   P+    P     +LR        P+     SQ   +    NP T
Sbjct: 4563 PLTEPAITANF-SLFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP----P 285
                         P+ LP      P S+QQ+         M +   P+ E+   P     
Sbjct: 4622 ------------PPSSLP---PTPPPSVQQK---------MVNGVTPSEELGEHPKDAAS 4657

Query: 286  GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQ-----Q 340
              D          VK  D+   + + P N+TE  + + +     P+ + P+++      +
Sbjct: 4658 ARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717

Query: 341  EAPIEP---------------PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ 385
            EAP  P               PV P+    SI     PV P   P          E PG+
Sbjct: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASI-----PVFPDTKP----YGALGLEVPGK 4768

Query: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL--VHQEATTRLS 443
             P    VT    G           VS     V LT++A  +  +   +  V +  + ++ 
Sbjct: 4769 LP----VTTWEKG-------KGSEVS-----VMLTVSAAAAKNLNGVMVAVAELLSMKIP 4812

Query: 444  GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHP 503
             S   + P +    G    P+  E  GP   ++    +SP+      P   +Q  A    
Sbjct: 4813 NSYEVLFPESPARAGTE--PKKGEAEGPGGKEKGLEGKSPD----TGPDWLKQFDAVLPG 4866

Query: 504  QTAEEGES--SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
             T +      SL  QE+PA  P         P +HS+     V  LD+     P  +   
Sbjct: 4867 YTLKSQLDILSLLKQESPAPEP---------PTQHSY--TYNVSNLDVRQLSAPPPEEPS 4915

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
                 +  +P  PP + + +L          P +  A+ PV PS       L L  +PE 
Sbjct: 4916 PPPSPLAPSPASPPTEPLVEL----------PTEPLAEPPV-PS------PLPLASSPES 4958

Query: 622  TTEVGHSTPPK 632
                  + PP+
Sbjct: 4959 ARPKPRARPPE 4969



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 26/147 (17%)

Query: 692 PPGHPEVTLPPSDKG--QAQHSHLTQATVQ-------PLDLELTITTKPTTEVKPSPTTE 742
           P G    ++ P + G  Q +   L +A VQ       PL+ E+ +   P  E   SP  E
Sbjct: 396 PKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPE-ESPLSPPPE 454

Query: 743 ETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTE--VTGPPTE--LE 798
           E+ T PP     + P P          E   +P P+ +  L R L E  ++ PP E  L 
Sbjct: 455 ESPTSPPPEASRLSPPPE---------ELPASPLPEALH-LSRPLEESPLSPPPEESPLS 504

Query: 799 PAQDSLVQSESYTQNKALTAPEEHKAS 825
           P  +S     S  +   L+ PEE   S
Sbjct: 505 PPPES--SPFSPLEESPLSPPEESPPS 529



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 13/145 (8%)

Query: 234  QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV-QPPGEDQAYY 292
            +   L+ ++P   P  L++  + +    P    +S ++ L+L   E    +PP +    Y
Sbjct: 4841 KEKGLEGKSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTY 4896

Query: 293  HLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-EPPVPPM 351
            ++ N+ V+         S P  E  S       P       EP       P+ EPPVP  
Sbjct: 4897 NVSNLDVRQL-------SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP 4949

Query: 352  EHELSISEQQQPVQPSESPREVESS 376
                S  E  +P   +  P E E S
Sbjct: 4950 LPLASSPESARPKPRARPPEEGEDS 4974


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 170/801 (21%), Positives = 291/801 (36%), Gaps = 100/801 (12%)

Query: 58  DSWSSHSSHFPR--ESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDS 115
           +S S  ++ FP   E   +PT P                M  P +ES  + + F+ T   
Sbjct: 120 ESTSDSTTLFPSSTEDTSSPTTPE----------GTDVPMSTPSEESISSTMAFVST--- 166

Query: 116 AGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQS 175
           A     E    L  + D+   L+   +   SP   +     + + +E  G T   S P S
Sbjct: 167 APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSE--GSTPLTSMPAS 224

Query: 176 QKQTLQNE-YSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE------TQNPE 228
             +   +E  +   TP   S P  +  ++   P  +E  GPS  +  P       T+ P 
Sbjct: 225 TMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE--GPSLSNSAPSGGSTPLTRMPL 282

Query: 229 TLEDIQSSSLQQ----EAPAQLPQLLEEEPSSMQQ--EAPALPPESSMESLT-LPNHEVS 281
           ++  + SS         A   +P +   E SS     E  ++P  +  E  T L +   S
Sbjct: 283 SVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTYTEGSTPLTSTPAS 342

Query: 282 VQPPGEDQAYYHLPNITVKPADVEVTITS-----------EPTNETESSQAQQETPIQFP 330
             P    +    +  +++ P D    +T+           E T+   S+ ++  TP+   
Sbjct: 343 TMPVATSE----MSTLSITPVDTSTLVTTSTEPSSLPTTAEATSMLTSTLSEGSTPLTNM 398

Query: 331 EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ---PP 387
                     EA     +P ++ +  ++   +    S SP   E +     TP +   P 
Sbjct: 399 PVSTILVASSEASTTSTIP-VDSKTFVTTASEA---SSSPTTAEDTSIATSTPSEGSTPL 454

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
               V+ +P    +  +L++  V  K    Q+T + E S+   T+ V+   T+  S    
Sbjct: 455 TSMPVSTTPVASSEASNLSTTPVDSK---TQVTTSTEASSSPPTAEVNSMPTSTPSEGST 511

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
            +   ++       +P +S EA  L         S  P++   P  T  EA++    T  
Sbjct: 512 PLTSMSVS-----TMPVASSEASTL---------STTPVDTSTPVTTSSEASSS--STTP 555

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM 567
           EG S  T   +   TP     V  +    S  +  +  P D    +T  S  E   S T 
Sbjct: 556 EGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTTPADSNTFVTTSS--EASSSSTT 613

Query: 568 KETPTQPPKK------VVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            E  + P          +  + V   +   +     +  PV  +  V         T   
Sbjct: 614 AEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLSTTPVDSNTPVTT---STEATSSS 670

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           TT  G S P   T      P  ++P    +       T +T  P+D    +T  +     
Sbjct: 671 TTAEGTSMPTS-TYTEGSTPLTSMPVNTTLVASSEASTLSTT-PVDTSTPVTTSTEASSS 728

Query: 682 PSTA----LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
           P+TA    + T+ P  G   +T  P  K     S  +  +  PLD    ITT  +TE   
Sbjct: 729 PTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEASTLSTTPLDTSTHITT--STEASC 786

Query: 738 SPTTEETSTQP---PDLGLAIIPE-PTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGP 793
           SPTT E ++ P   P  G  ++   P + T  ++    T +  P    +   + TEV+  
Sbjct: 787 SPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVDSNSPVTTSTEVSSS 846

Query: 794 PTELEPAQDSLVQSESYTQNK 814
           PT   PA+ + + + +Y++ +
Sbjct: 847 PT---PAEGTSMPTSTYSEGR 864



 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 160/776 (20%), Positives = 266/776 (34%), Gaps = 66/776 (8%)

Query: 71   SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQ 130
            S  +P L + P     +    +S +   P +S   ++    T       P+  E      
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVI----TSTEVSSSPIPTEGTSMQT 2153

Query: 131  QDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSS--TD 188
                D+ +P   +PVS   +        S   +   T   ++ +++     +E +S  T 
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 2213

Query: 189  TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEP-ETQNPETLEDIQSSSLQQEAPAQLP 247
            TP  GS P      S  P   SE    S     P +T  P T     +SS        +P
Sbjct: 2214 TPSEGSTPFTSMPVSTMPVVTSEA---STLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 248  QLLEEEPSSMQQEAPA---LPPESSMESL-TLP---------NHEVSVQPPGEDQAYYHL 294
                 E ++     P    L   S + +L T P         + E S  PP  +     +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT--SM 2328

Query: 295  PNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
            P  T    +  +T        + S  T+   ++ A   TP+    +   S T  +    P
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 347  PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLA 406
                 E    ++       P  S      S T  +T        E + SP     T    
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448

Query: 407  SPSVSVKPPDVQLTIAAEP--SAEVGT-----------SLVHQEATTRLSGSGNDVEPPA 453
            SP      P   + ++  P  S+E GT                EA++  + + + V P +
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508

Query: 454  IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513
                G  LL        P+A   E S  S  P+++ +P  T  E ++    T+ EG S  
Sbjct: 2509 TASEGSTLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTSMP 2565

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSP-TMKET-- 570
            T   +   TP     V  +P   S  +  +  P+D    +T  + TE   SP T K+T  
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT--TSTETSSSPTTAKDTSM 2623

Query: 571  PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTP 630
            P   P +V   L      T P    + +    +P  T  L+      +  PTT  G S P
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA----L 686
               +    +   +T          +S  +  +  P+D    +T  +     P+TA    +
Sbjct: 2684 --TSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETST 746
              + P  G   +T           S  +  +   +D  + +TT  +TE   SPTT E ++
Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT--STEASSSPTTAEVTS 2799

Query: 747  Q----PPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
                 P +    +   P   T  +++   T +  P    T   + T+ +  PT  E
Sbjct: 2800 MPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 148/686 (21%), Positives = 229/686 (33%), Gaps = 70/686 (10%)

Query: 170  LSTPQSQKQTL--QNEYSSTDTPYPGSLPP-----ELRVKSDEPPGPSEQVGPSQFHLEP 222
            L+TP   K  +   NE SS+ TP  G+  P     E R      P  +  V  S   +  
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILS 1358

Query: 223  ET----QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAP-ALPPESSMESLTLPN 277
             T      P T      SS        +P     E ++     P +  P  S E+ TL  
Sbjct: 1359 TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSA 1418

Query: 278  HEVSVQPPGEDQAYYHLPNITVK--------PADVEVTITSEPTNETESSQAQQETPIQF 329
              V    PG   A       T +        P++ +  + S P + T  + ++  T    
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQ--------PVQPSE-SPREVESSPTQQ 380
            P +         A    P P     ++IS   +        PV  +  +  E+ S  T  
Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTP 1538

Query: 381  ETPGQPPEHHEVTVSPPG-------HHQTHHLASPSVSVKPPDVQLTIAAEP-------- 425
                 P   +    S P           T+   S  ++  P    L +++E         
Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598

Query: 426  -SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
             S    T+     ++T   GS   +  P+    G PLL        P+A   E S  S  
Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPS---EGSPLLTSIPVSTTPVA-SPEASTLSTT 1654

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            P+++ +P  T  E ++    T  EG S  T      +TP     V   P   S ++  + 
Sbjct: 1655 PVDSNSPVITSTEVSSS--PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             P+D    +T  + TE   SPT  E  + P   P +    L      T P    + +   
Sbjct: 1713 TPVDNSTPVT--TSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRA 661
             +P  T   +      T  PTT  G S P   T+     P  + P        +S  +  
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTS-TLSEGMTPLTSTP-VSHTLVANSEASTL 1828

Query: 662  TVQPLDLGFTITPKSMTEVEPSTALMTT-APPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P+D        S + V  STA+ ++  P  G    T  PS+   A  S     T   
Sbjct: 1829 STTPVD--------SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA 1880

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRH---STALEKTTAPRP 777
                 T++T P     P  T  + S+ P     + +P  T        ++    TT    
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDS 803
              + TL  +L +   P T    A  S
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSS 1966



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 165/734 (22%), Positives = 246/734 (33%), Gaps = 110/734 (14%)

Query: 165  GITRQLSTPQSQKQTLQNEYSS-TDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
            G T   S P S K    +E S+ + TP   S+P     ++   P  ++           +
Sbjct: 2572 GSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK-----------D 2620

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEP--SSMQQEAPALPPESSMESLTLPNHEVS 281
            T  P +     S+SL     + +P    E    S+   +   L   S+  S +    E S
Sbjct: 2621 TSMPISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGS 2680

Query: 282  VQP---PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSAT 338
              P   PGE      L NI V        + +   +   ++     TP+    E   S T
Sbjct: 2681 SMPTSTPGERST--PLTNILVSTT----LLANSEASTLSTTPVDTSTPVTTSAEASSSPT 2734

Query: 339  QQEAP---IEPPVPPMEHELSISEQQQPVQPSESPR----------------EVESSPTQ 379
              E     I  P        SI     PV  SE+                  E  SSPT 
Sbjct: 2735 TAEGTSMRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTT 2794

Query: 380  QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEAT 439
             E    P      T +P      +H  +P  S +   +  T   + S  V TS     + 
Sbjct: 2795 AEVTSMPTSTPSETSTPLTSMPVNH--TPVASSEAGTLSTT-PVDTSTPVTTSTKASSSP 2851

Query: 440  TRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
            T   G    V P +    G  LL        P+A   E S  S  P++   P  T  E +
Sbjct: 2852 TTAEGI---VVPISTASEGSTLLTSIPVSTTPVA-SSEASTLSTTPVDTSIPVTTSTEGS 2907

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT 559
            +  P TAE G S      +   TP    +V   P   S  +  +  P+D    +T  +  
Sbjct: 2908 SS-PTTAE-GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT--TSA 2963

Query: 560  EVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
            E   SPT  E  + P   P +    L      T P    + +    +P+ T   +     
Sbjct: 2964 EASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTE 3023

Query: 617  ITPEPTTEVGH----STPPKR----TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDL 668
             +  PTT  G     STP +     T +      V +P    + T         V   ++
Sbjct: 3024 ASSSPTTAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEV 3083

Query: 669  GFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTIT 728
              + TP   T +  ST    + P  G P  T P +       S ++  +  P+D    +T
Sbjct: 3084 SSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTS------SAISTLSTTPVDTSTPVT 3137

Query: 729  TKPTTEVKPSPTTEETSTQP------------------------PDLGLAIIPEPT---- 760
            T  +TE   SPTT E ++ P                         D  L+  P  T    
Sbjct: 3138 T--STEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPV 3195

Query: 761  ---TETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---TELEPAQDSLVQSESYTQNK 814
               TE   ST  E T+ P      T    +T +T  P   T +  ++ S++ +     N 
Sbjct: 3196 TTSTEATSSTTAEGTSIP----TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNT 3251

Query: 815  ALTAPEEHKASTST 828
             LT   E  +S  T
Sbjct: 3252 PLTTSTEASSSPPT 3265



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 171/856 (19%), Positives = 280/856 (32%), Gaps = 92/856 (10%)

Query: 43   VKDPLQLTSNPLGPPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
            V   + +T++        ++  +  P  +P   + P      +H  P ASSE        
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT-PVASSEAGTLSTTP 2834

Query: 103  TENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAE 162
             +   P + T   A   P   E  +       +  +    +PVS   +    A   S   
Sbjct: 2835 VDTSTP-VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893

Query: 163  I---IGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFH 219
            +   I +T   +   S   T +       TP   S P    + S  P   SE    S   
Sbjct: 2894 VDTSIPVTTS-TEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA---STLS 2949

Query: 220  LEP-ETQNPETLEDIQSSSLQQEAPAQLP-QLLEEEPSSMQQEAPALPPESSMESLTLPN 277
              P +T+ P T     SSS        +P     E  + +   + +  P +S E+ TL  
Sbjct: 2950 TTPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSR 3009

Query: 278  HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSA 337
                   P            T +   + ++  SE +    S      TP+  PE    S 
Sbjct: 3010 TPADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLST 3068

Query: 338  T--QQEAPI-------EPPVPPMEHELSISEQQQPVQP------------SESPREVESS 376
            T     +P+         P P     + IS   +   P            S +   + ++
Sbjct: 3069 TPVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTT 3128

Query: 377  PTQQETP-GQPPEHHEVTVSPPGHHQ---THHLASPSVSVKPPDVQLTIAAEPSAEVGTS 432
            P    TP     E H    +  G      T    S  ++  P    L +++E S    T 
Sbjct: 3129 PVDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATP 3188

Query: 433  L-------VHQEATTRLSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSP 483
            +          EAT+  +  G  +       G  PL  +P S+    P+A   E S  S 
Sbjct: 3189 VDTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT---PVA-SSEASILST 3244

Query: 484  EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             P+++  P  T  EA++  P    EG S  T   +   TP     V       S  +  +
Sbjct: 3245 TPVDSNTPLTTSTEASSSPPTA--EGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLS 3302

Query: 544  VQPLDLGFTITPESKTEVELSPTMKE---TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
              P D    +T  S  +   SP + +    PT    +    L      T P    + +  
Sbjct: 3303 TTPADTSTPVTTYS--QASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTL 3360

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH---PEVTLPHPDQVQTQHSH 657
              +P  T   +      +  PTT  G S P      SP     P  ++P         S 
Sbjct: 3361 STTPVDTSTPVTTSTEASLSPTTAEGTSIPTS----SPSEGTTPLASMP-VSTTPVVSSE 3415

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPS----TALMTTAPPPGHPEVTLPPSDKGQAQHSHL 713
            +   +  P+D    +T  +     P+    T+L T+    G   +++ P        S  
Sbjct: 3416 VNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEA 3475

Query: 714  TQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG------LAIIPEPTTETRHST 767
            +  +  P+D    +TT   T    SPTT E ++ P          L  +P  TT    S 
Sbjct: 3476 STLSTTPVDTSTPVTTSSPT--NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSE 3533

Query: 768  ALEKTTAPRPDRVQTLHRSLTEVTGPPTELE--------PAQDS-----LVQSESYTQNK 814
            A   +T P      T   S ++ +  P  L+        P++ S     ++ S +Y  + 
Sbjct: 3534 ASTLSTTPVDS--NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSS 3591

Query: 815  ALTAPEEHKASTSTNI 830
              + P       ST +
Sbjct: 3592 EASTPSTPSVDRSTPV 3607



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 129/590 (21%), Positives = 202/590 (34%), Gaps = 81/590 (13%)

Query: 267  ESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETP 326
            E+S    T     + +  P E       P +T  P  +   +TS   +   ++     +P
Sbjct: 783  EASCSPTTTEGTSMPISTPSEGS-----PLLTSIPVSI-TPVTSPEASTLSTTPVDSNSP 836

Query: 327  IQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ----------------QPVQ---PS 367
            +    EV  S T  E    P     E    ++                    PV    P 
Sbjct: 837  VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896

Query: 368  ESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL-TIAAEP- 425
             +  E  SSPT  E    P        S PG   T   + P  +      +  T++A P 
Sbjct: 897  TNSTEARSSPTTSEGTSMP-------TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPV 949

Query: 426  --SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
              S  V TS     + T   G+      P+   G  PL   S+  +  L    E S  S 
Sbjct: 950  DTSTPVTTSTEATSSPTTAEGTSIPTSTPS--EGTTPLT--STPVSHTLVANSEASTLST 1005

Query: 484  EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             P+++  P  T  EA++  P    EG S  T   +   TP                   T
Sbjct: 1006 TPVDSNTPLTTSTEASS--PPPTAEGTSMPTSTPSEGSTP------------------LT 1045

Query: 544  VQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-- 601
              P+      + E+ T +  +P    TP     +         G + PT    +   P  
Sbjct: 1046 RMPVSTTMVASSETST-LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLT 1104

Query: 602  ---VSPSVTVQLLDLGLTITPEPTT-EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH 657
               VS  + V      L+ TP  T+  V  ST    +  + +   +    P +  T  + 
Sbjct: 1105 SVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS 1164

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHL 713
            +  +T   L +       S T V+  T + T+    +PPP     ++P S  G+ + + L
Sbjct: 1165 MPVSTT--LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE-RSTPL 1221

Query: 714  TQATVQPLDLEL----TITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTAL 769
            T   V+   +      T++T P     P  T+ ETS+ P       +P  TT +  ST L
Sbjct: 1222 TSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTT-SEGSTLL 1280

Query: 770  EKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
              T+ P    + T   + T +T P     P   S   S S T  +  + P
Sbjct: 1281 --TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 175/835 (20%), Positives = 283/835 (33%), Gaps = 130/835 (15%)

Query: 50   TSNPLGPPDSWSSHSSHFPRE-----SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            TS P+  P   S   +  P       SP A TL   P D  +   + S+E+ + P  +  
Sbjct: 794  TSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD-SNSPVTTSTEVSSSPTPAEG 852

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKK-LKKDPAQRWSLAEI 163
              +P   +  S G  PL     +++       +S     PV     +      R S    
Sbjct: 853  TSMP--TSTYSEGRTPLTSMP-VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTS 909

Query: 164  IGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
             G +   STP      L +   ST TP   S   E R  S  P   S  V  S       
Sbjct: 910  EGTSMPTSTPGEGSTPLTSMPDST-TPVVSS---EARTLSATPVDTSTPVTTST----EA 961

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS----MQQEAPALP--PESSMESLTLPN 277
            T +P T E    +S+    P++    L   P S       EA  L   P  S   LT   
Sbjct: 962  TSSPTTAE---GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 278  HEVSVQPPGEDQAYYHLPNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQF 329
               S  P  E  +   +P  T       +T        + S  T+   ++ A   TP+  
Sbjct: 1019 EASSPPPTAEGTS---MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT 1075

Query: 330  PEEVEPSATQQEAPIEPPVP-----------PMEHELSISEQQQPVQ--------PSESP 370
              +   S+T  +    P              P+   L +S +   +         P  + 
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTS 1135

Query: 371  REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVG 430
             E  SSPT  E    P        SPP    T  LAS  VS       L +++E +  + 
Sbjct: 1136 TEASSSPTTAEGTSIP-------TSPPSEGTTP-LASMPVSTT-----LVVSSEANT-LS 1181

Query: 431  TSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA---------VQQETSFQ 481
            T+ V  +     S   +   P A     P   P   E + PL             E S  
Sbjct: 1182 TTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP--GERSTPLTSMPVRHTPVASSEASTL 1239

Query: 482  SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
            S  P++   P  T  E ++  P TAE G S  T     + T E   ++ + P   + +T 
Sbjct: 1240 STSPVDTSTPVTTSAETSSS-PTTAE-GTSLPT-----STTSEGSTLLTSIPVSTTLVTS 1292

Query: 542  ATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
                 L    T   ++K  V  S  +  +PT             +G + PT    + + P
Sbjct: 1293 PEASTL---LTTPVDTKGPVVTSNEVSSSPTPA-----------EGTSMPTSTYSEGRTP 1338

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPE----VTLP--HPDQVQTQ- 654
            ++       L     I+   TT V +STP   +  +   P      ++P  +P +  T  
Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPL 1398

Query: 655  -----------HSHLTRATVQPLDLGFTITPKSMTEVEPSTA----LMTTAPPPGHPEVT 699
                        S  +  +  P+D     T  +     P+TA    + T+ P  G   + 
Sbjct: 1399 TSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLK 1458

Query: 700  LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT--TEETSTQPPDLGLAIIP 757
              P       +S  +  +  P+D    + T       P+P   T    + P +   A+  
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518

Query: 758  EPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQ 812
             P + T  +++   + +  P    T   + ++ +  PT    A  + +Q+ +Y++
Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPT---TADGTSMQTSTYSE 1570



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 176/833 (21%), Positives = 265/833 (31%), Gaps = 135/833 (16%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P  S  A TL A P D    G +++    +P   +T   +    +  S G+ PL+    +
Sbjct: 1407 PVVSSEASTLSATPVDTSTPGTTSAEATSSP---TTAEGISIPTSTPSEGKTPLKSIP-V 1462

Query: 128  ASQQDLKDKLSPQERLPVSPKK---------LKKDPAQRWSLAEII---GITRQLSTPQS 175
            ++      + S     PV                 PA+  S+A      G T   S P S
Sbjct: 1463 SNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVS 1522

Query: 176  QKQTLQNEYSS-TDTPYPGSLPPELRVKSDEPP----GPSEQVGPSQFHLEPETQNPETL 230
                  +E +S + TP   S P     ++   P    G S Q         P T  P + 
Sbjct: 1523 TTTVASSEINSLSTTPAVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVST 1582

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQA 290
              + SS             L   P   + +  A    SS  S T     +++  P E   
Sbjct: 1583 MLVVSSEANT---------LSTTPIDSKTQVTASTEASS--STTAEGSSMTISTPSEGS- 1630

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                P +T  P      + S   +   ++     +P+    EV  S T  E    P    
Sbjct: 1631 ----PLLTSIPVST-TPVASPEASTLSTTPVDSNSPVITSTEVSSSPTPAEGTSMPTSTY 1685

Query: 351  MEHEL---SISEQQQPVQ----------------PSESPREVESSPTQQETPGQPPEHHE 391
             E      SI+ +  PV                 P  +  E  SSPT  E    P     
Sbjct: 1686 TEGRTPLTSITVRTTPVASSAISTLSTTPVDNSTPVTTSTEARSSPTTSEGTSMPNSTPS 1745

Query: 392  VTVSPPGHHQTHHLASPSVSVKP--PDVQLTIAAEPSAEVGTSLVHQEATTR-LSGSGND 448
               +P        L S  VS  P       T++A P           EAT+   +  G  
Sbjct: 1746 EGTTP--------LTSIPVSTTPVLSSEASTLSATPIDTSTPVTTSTEATSSPTTAEGTS 1797

Query: 449  VEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENP---------SPTQQEAA 499
            +    +  G  PL   S+  +  L    E S  S  P+++ +P         SPT  E  
Sbjct: 1798 IPTSTLSEGMTPLT--STPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGT 1855

Query: 500  AEHPQTAEEGESSLTH------------------QEAPAQTPEFPNVVVAQPP---EHSH 538
            +    T  EG ++LT                     A   TP      V+  P   + S 
Sbjct: 1856 SIATSTPSEGSTALTSIPVSTTTVASSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSS 1915

Query: 539  LTQATVQPLDLGFTITPESKTEVE------LSPTMKET--PTQPPKKVVPQLRVYQGVTN 590
            +  +T +      T  P S T V       LS T+ +T  P     +         G + 
Sbjct: 1916 MPTSTPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYSQASSSPTTADGTSM 1975

Query: 591  PTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
            PTP   +   P++       L +    +   TT V  STP   +      P        Q
Sbjct: 1976 PTPAYSEGSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEGSSSPTTAGGTSIQ 2035

Query: 651  VQTQHSHLTRATVQPLDLGFTITPK----------SMTEVEPST-----------ALMTT 689
              T     T     P+     ++ +          S T+V  ST           ++  +
Sbjct: 2036 TSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNSTEASSSATAEGSSMTIS 2095

Query: 690  APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP-TTEETSTQP 748
            AP  G P +T  P           +  +  P+D    + T  +TEV  SP  TE TS Q 
Sbjct: 2096 APSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVIT--STEVSSSPIPTEGTSMQT 2153

Query: 749  ---PDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
                D    +   P + T  +++   T +  P    T   + TE    PT  E
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSE 2206



 Score = 58.5 bits (140), Expect = 5e-08
 Identities = 170/825 (20%), Positives = 268/825 (32%), Gaps = 116/825 (14%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
            P  SSE         +   P + T   A   P   E          +  +P   +PVS  
Sbjct: 3351 PVVSSEASTLSTTPVDTSTP-VTTSTEASLSPTTAEGTSIPTSSPSEGTTPLASMPVSTT 3409

Query: 149  KLKKDPAQRWSLAEIIGITR-QLSTPQSQKQTLQNEYS-STDTPYPGSLPPELRVKSDEP 206
             +        S   +   T    ST  S   T+    S  T T   GS P  +   S  P
Sbjct: 3410 PVVSSEVNTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTP 3469

Query: 207  PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP 266
               SE    S       T   +T   + +SS    +P                E  ++P 
Sbjct: 3470 VASSEASTLS-------TTPVDTSTPVTTSSPTNSSPTTA-------------EVTSMPT 3509

Query: 267  ESSMESLT-LPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
             ++ E  T L N  VS  P    +A      ++  P D    +TS  +  + S    Q T
Sbjct: 3510 STAGEGSTPLTNMPVSTTPVASSEA----STLSTTPVDSNTFVTSS-SQASSSPATLQVT 3564

Query: 326  PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ 385
             ++     E S++     +          ++ SE   P  PS       ++ TQ  +   
Sbjct: 3565 TMRMSTPSEGSSSLTTMLLSSTY------VTSSEASTPSTPSVDRSTPVTTSTQSNSTPT 3618

Query: 386  PPEHHEVTVSPPGHHQTHHLASP----SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            PPE   + +S P    T     P    SV++       T+  + S  V TS     +   
Sbjct: 3619 PPEVITLPMSTPSEVSTPLTIMPVSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVT 3678

Query: 442  LSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
              G+   +  P+   G  PL  +P S+          E S  S   +    P  T  EA 
Sbjct: 3679 PEGTTMPIWTPS--EGSTPLTTMPVSTTRV----TSSEGSTLSTPSVVTSTPVTTSTEAI 3732

Query: 500  AEH------------PQTAEEGESSLTHQEAP------AQTPEFPNVVVAQPPEHSHLTQ 541
            +              P       +++     P      + TP  P+V  +     +  ++
Sbjct: 3733 SSSATLDSTTMSVSMPMEISTLGTTILVSTTPVTRFPESSTPSIPSVYTSM--SMTTASE 3790

Query: 542  ATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             +  P  L  T T    T  E S  +      P   + P     +  T  TP  D +   
Sbjct: 3791 GSSSPTTLEGTTTMPMSTTSERSTLLTTVLISPISVMSPS----EASTLSTPPGDTSTPL 3846

Query: 602  VSP------SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
            ++       S+  ++  + ++IT E       STP    +VS      TLP      T  
Sbjct: 3847 LTSTKAGSFSIPAEVTTIRISITSE------RSTPLTTLLVS-----TTLP------TSF 3889

Query: 656  SHLTRATVQPLDLGFTITPKSMTEVEP--------STALMTTAPPPG------HPEVTLP 701
               + A+  PLD   T TP + T   P        S +++T    PG         VT  
Sbjct: 3890 PGASIASTPPLDTSTTFTPSTDTASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSS 3949

Query: 702  PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQPPDLGLAIIP 757
             +D   A    ++   +   +L    T+  +T    S T E T    +T  P   + +  
Sbjct: 3950 TADVFPATTGAVSTPVITSTELNTPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMST 4009

Query: 758  EPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALT 817
             P+T    S     T+A       T H S +  T P T   P+ +S   S   +     T
Sbjct: 4010 APSTPRTTSRGC-TTSASTLSATSTPHTSTSVTTRPVT---PSSESSRPSTITSHTIPPT 4065

Query: 818  APEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNT 862
             P  H ++  T      T   E ++ +    +   R    P   T
Sbjct: 4066 FPPAHSSTPPTTSASSTTVNPEAVTTMTTRTKPSTRTTSFPTVTT 4110



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 76/352 (21%), Positives = 128/352 (36%), Gaps = 38/352 (10%)

Query: 477 ETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
           E+S  S  P +++   +PT+    +E    +     S T   +   TPE  +V ++ P E
Sbjct: 95  ESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE 154

Query: 536 HS-HLTQATVQPLDL-------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQG 587
            S   T A V    L         T   +  T +  S     +PT P    +P+    +G
Sbjct: 155 ESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEG 214

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH 647
            T P      +   V+ S  + LL   + I+   T     S+ P     + + P ++   
Sbjct: 215 ST-PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSP----TTAEGPSLSNSA 269

Query: 648 PDQVQTQ------------HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
           P    T              S  +  +  P      +   +     P+TA  T+ P   +
Sbjct: 270 PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTY 329

Query: 696 PEVTLP----PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
            E + P    P+       S ++  ++ P+D    +TT  +TE    PTT E ++     
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTT--STEPSSLPTTAEATSMLTST 387

Query: 752 GLAIIPEPTTETRHSTAL-----EKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
            L+    P T    ST L       TT+  P   +T   + +E +  PT  E
Sbjct: 388 -LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 174/801 (21%), Positives = 294/801 (36%), Gaps = 134/801 (16%)

Query: 86   HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQER 142
            HLGP    E       P+   E+L   + T D    +  +P++         +K+  Q  
Sbjct: 955  HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006

Query: 143  LPVSP--KKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
            + +SP  K + KD  + +   E     + L     +K+ +      S     PG+LP   
Sbjct: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066

Query: 197  PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
              L       P  +++VG +    + + Q   TL   Q+  L      Q  Q LE   + 
Sbjct: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125

Query: 257  MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
             Q +A   P  P ++ ++ +TL         P +DQA    P I++              
Sbjct: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
                ++Q  Q+  I       P   QQ   +  P+ P +  EL I     P+ P ++   
Sbjct: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203

Query: 372  EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
             V  +P Q +  G P  P+  +         Q   L  P    +   + +T+  +   E+
Sbjct: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263

Query: 430  GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
            G  L  Q+A       G  + P   Q  G PL P+ ++  G PL  +Q  +   P     
Sbjct: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
              P   Q       PQ A+  E +LT Q+A     P  T +   + +   P+H+    + 
Sbjct: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
              T Q  +LG  +TP+    + +  T ++        TP Q  +  +P           T
Sbjct: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
                QAQ    P    Q  +LG+T+TP+   E+G    P++       ++ P+  E+ +P
Sbjct: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
               Q Q Q   +     Q  +LG  +TP      + + AL     PP   E+ +P     
Sbjct: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
                  LT   VQ L + L        E+  +P   +      T  Q  +LG+ + P+  
Sbjct: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596

Query: 761  TETRHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
             E       ++  A      P + Q L  SLT        +T  P + +     +    +
Sbjct: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656

Query: 810  YTQNKALTAPEEHKASTSTNI 830
            +     LT+ + H   +  N+
Sbjct: 1657 WVSAVTLTSEQTHALESPMNL 1677


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 89.0 bits (219), Expect = 4e-17
 Identities = 147/598 (24%), Positives = 197/598 (32%), Gaps = 88/598 (14%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P  +  T T  PT    S+Q+   TPI     V P+ T       P   P+    +++  
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 1371

Query: 361  QQPV---QPSESPREVES------SPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVS 411
              P     P+ +P    +      +PT  +TP   P     TV+P     T         
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP-----TPTPTGTQTP 1426

Query: 412  VKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP 471
               P    T         GT      A T  S       P   Q   P   P ++     
Sbjct: 1427 TTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQ--TPTTTPITT----- 1479

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
                  T   +P P   + P+PT     A    T      + T  + P  TP      V 
Sbjct: 1480 ----TTTVTPTPTPTGTQTPTPT-----AITTTTTVTPTPTPTGTQTPTSTPITTTTTVT 1530

Query: 532  QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P  +     T  P+    T+TP        +PT  +TPT  P               P
Sbjct: 1531 PTPTPTGTQTPTPTPISTTTTVTPTP------TPTGTQTPTTTPITTTT-------TVTP 1577

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL---PHP 648
            TP     Q P     T  L+    T+TP PT      T  K T V+P     T+   P P
Sbjct: 1578 TPTPTGTQTP-----TTVLITTTTTMTPTPT-----PTSTKSTTVTPITTTTTVTATPTP 1627

Query: 649  DQVQTQH----SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSD 704
               QT      S  T  T  P     +  P + T   P   L T+ PP   PE + P + 
Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP---PESSTPQTS 1684

Query: 705  KGQAQHSHLTQAT----VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPT 760
            +  +  S LT++T      P  +E+T T  P+T   P+ T+   +  PP         P 
Sbjct: 1685 RSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP--STTTSPPG 1740

Query: 761  TETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---------TELEPAQDSLVQSESYT 811
            T TR  T    ++AP P  VQT   S    T  P         T L P   S++      
Sbjct: 1741 TPTR-GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--ICCV 1797

Query: 812  QNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
             N    AP EE    T  + C    C    LSC            P P P     T T
Sbjct: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCPSTPSPTPTPSKSTPT 1852



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 97/389 (24%), Positives = 127/389 (32%), Gaps = 61/389 (15%)

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQ 573
            T  E P  TP      V   P  +     T  P+    T+TP        +PT  +TPT 
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP------TPTGTQTPTT 1359

Query: 574  PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKR 633
             P               PTP     Q P +  +T        T+TP P T  G  TP   
Sbjct: 1360 TPITTTT-------TVTPTPTPTGTQTPTTTPITTT-----TTVTPTP-TPTGTQTPTST 1406

Query: 634  TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP---KSMTEVEPSTALMTTA 690
             I +      T P P   QT        T  P+    T+TP    + T+    TA+ TT+
Sbjct: 1407 PITTTTTVTPT-PTPTGTQT-------PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTS 1458

Query: 691  -------PPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE 743
                   P       T P +       +     T  P    +T TT  T    P+ T   
Sbjct: 1459 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP 1518

Query: 744  TSTQPPDLGLAIIPEPT-------TETRHSTALEKTTAPRPDRVQTLH----RSLTEVTG 792
            TST P      + P PT       T T  ST    T  P P   QT       + T VT 
Sbjct: 1519 TST-PITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1577

Query: 793  PPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT-------CGDEMLSCID 845
             PT       + V   + T       P   K++T T I    T        G +  + I 
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637

Query: 846  LNPEQRLRQVPVPE-----PNTHNGTFTI 869
            ++    +   P P      P TH  T  I
Sbjct: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPI 1666



 Score = 42.0 bits (97), Expect = 0.005
 Identities = 96/494 (19%), Positives = 149/494 (30%), Gaps = 98/494 (19%)

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G     +TP +   T+    + T T  P S P          P P+    P+     P T
Sbjct: 1376 GTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT---TPIT 1432

Query: 225  QNPETLEDIQSSSLQQEAPAQLP--QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV 282
                       +  Q   P  +     +   P+    + P   P ++  ++T        
Sbjct: 1433 TTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 1492

Query: 283  QPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
            Q P               P  +  T T  PT     +Q    TPI     V P+ T    
Sbjct: 1493 QTP--------------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGT 1538

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP---PGH 399
                P P     +S +    P            +PT  +TP   P     TV+P   P  
Sbjct: 1539 QTPTPTP-----ISTTTTVTPT----------PTPTGTQTPTTTPITTTTTVTPTPTPTG 1583

Query: 400  HQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP 459
             QT     P+  +      +T    P++   T++     TT ++ +     P       P
Sbjct: 1584 TQT-----PTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT-----PTPTGTQTP 1633

Query: 460  PLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAP 519
             ++P S+           T   +P P       PT       H  TA   E + ++    
Sbjct: 1634 TMIPIST---------TTTVTPTPTPTTGSTGPPT-------HTSTAPIAELTTSNPPPE 1677

Query: 520  AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVV 579
            + TP+               +++T  PL    T+         L P ++ T T PP    
Sbjct: 1678 SSTPQ--------------TSRSTSSPLTESTTLLS------TLPPAIEMTSTAPPS--- 1714

Query: 580  PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPK 639
                     T   P      H +SP  +      G   TP   T  G S+ P  + V   
Sbjct: 1715 ---------TPTAPTTTSGGHTLSPPPSTTTSPPG---TPTRGTTTGSSSAPTPSTVQTT 1762

Query: 640  HPEVTLPHPDQVQT 653
                  P P  + T
Sbjct: 1763 TTSAWTPTPTPLST 1776



 Score = 35.0 bits (79), Expect = 0.62
 Identities = 47/199 (23%), Positives = 65/199 (32%), Gaps = 24/199 (12%)

Query: 681  EPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
            +P+T   TT   P    +T   +       +     T  P+    T+T  PT     +PT
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358

Query: 741  TEETSTQPPDLGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTE 789
            T   +T        + P PT   T+T  +T +  TT     P P   QT       + T 
Sbjct: 1359 TTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413

Query: 790  VTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPE 849
            VT  PT       +     + T       P   +A T T I    T        +   P 
Sbjct: 1414 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST--------VTPTPT 1465

Query: 850  QRLRQVPVPEPNTHNGTFT 868
                Q P   P T   T T
Sbjct: 1466 PTGTQTPTTTPITTTTTVT 1484


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 87.4 bits (215), Expect = 1e-16
 Identities = 166/771 (21%), Positives = 271/771 (35%), Gaps = 128/771 (16%)

Query: 79   ADPWDFDHLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD 135
            A+P + +   P A+      PA P E+ E       T   AG  P E  +  A+++    
Sbjct: 599  AEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAG--PTENREMTANEKTTLF 656

Query: 136  KLSPQE-RLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNE---YSSTDTPY 191
               P E R   + +K    PA+     +      + +T  S + T   E    ++ +T  
Sbjct: 657  PAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTL 716

Query: 192  PGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
              + P E R ++      +E+  P  F  EP      T  +  + S     PAQ  +  +
Sbjct: 717  SPAEPTENRERT-----ANEKTTP--FPAEPTENRERTANENTTPS-----PAQPTENGD 764

Query: 252  EEPSSMQQEAPALP-PESSMESLTLPNHEVSVQPPGEDQAYYHLP----NITVKPADVEV 306
              P + ++  P+L  P  + +     N + +       +     P    N T  PA    
Sbjct: 765  RTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPA---- 820

Query: 307  TITSEPTNETESSQAQQET--PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPV 364
                EPT   E +  ++ T  P +  E  E +A ++  P   P  P E+    + +   +
Sbjct: 821  ----EPTENRERTANEKTTQFPAEPTENRESTANEKTTPF--PAEPTENREWTANENTTL 874

Query: 365  QPSESPREVESSPTQQE----TPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
             P+E     E +P   E    +P +P E+ E T        T+   +PS +      + T
Sbjct: 875  SPAEPTEHEEMTPLANEKTTLSPAEPTENGERTPF------TNEKTTPSSAEPTEHGERT 928

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
                P A   T+    E T       N+   P+         P    E G   V ++T+ 
Sbjct: 929  ----PLANEITTPSRAEPTEHGERIANEKATPS---------PAKPTEHGETTVNEDTTP 975

Query: 481  QSPEPINNENPSPTQQEAAAEHP-QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
             S EP  N   +P   E     P ++ E GE +   +  P+          A+P EH   
Sbjct: 976  SSAEPTENGERTPLANENTTTSPTESTEHGERTANEKTTPSP---------AEPTEHGER 1026

Query: 540  TQATVQPLDLGFTI-TPESKTE-VELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQ 597
            T +  +      TI +P   TE  E++P+  E  T  P K                    
Sbjct: 1027 TPSANEK-----TIPSPAKPTEHEEMTPSANENTTPSPVK-------------------- 1061

Query: 598  AQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH 657
               P        L +  +T++PE  TE G  T      ++P     +L  P    T+H  
Sbjct: 1062 ---PTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITP-----SLAKP----TEHG- 1108

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
                T  P D   +   +S    + +T+     P P  P   +  + +    H  +TQ T
Sbjct: 1109 --ERTTSPNDKITSSAAESTEHRDRATSANVITPAPAEP---IKHAKRTTLAHEKMTQVT 1163

Query: 718  VQPLD--LELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAP 775
             +  +   + T TT+ TT     PT     T         +PE  TE   +T L   T  
Sbjct: 1164 EKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTETIK 1223

Query: 776  RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
             P           + T  P +      ++  S   T +K+LT    H   T
Sbjct: 1224 AP----------VKSTENPEKTAAVTKTIKPSVKVTGDKSLTTTSSHLNKT 1264



 Score = 83.2 bits (204), Expect = 2e-15
 Identities = 172/807 (21%), Positives = 284/807 (35%), Gaps = 121/807 (14%)

Query: 88   GPSASSEM---------PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
            GP+ + EM         PA P E  E       T   A  +P E  +  A++        
Sbjct: 341  GPTENREMTANENTTLFPAEPTEHGERTANENTTPSPA--EPTEHGERTANENTTPSPAE 398

Query: 139  PQE---RLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTD--TPYPG 193
            P E   R P +  K     A+     E   +  + +TP   + T   E ++ +  TP P 
Sbjct: 399  PTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPA 458

Query: 194  SLPPELRVKSDEPPGPSEQVGPSQFH----LEPETQNP-ETLEDIQSSSLQQE----APA 244
              P E R  +         V P++       E  T +P E  E+ Q +    E    + A
Sbjct: 459  G-PTENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSA 517

Query: 245  QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKPA 302
            +  +  E  P + +   P+ P E +       N + +  P  P E+     L N    P+
Sbjct: 518  EPTEHGERTPLANENTTPS-PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPS 576

Query: 303  DVEVTITSEPT---------NETESSQAQQETPI----QFPEEVEPSATQQEAPIE---- 345
              E T   + T         +  E ++ ++ TP+      P   EP+  ++    E    
Sbjct: 577  LAEPTENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTP 636

Query: 346  -PPVPPMEHELSISEQQQ--PVQPSESPREVESSPTQQETPGQPPEHHEVT--------- 393
             P  P    E++ +E+    P +P+E+ RE  ++     +P +P E+ + T         
Sbjct: 637  SPAGPTENREMTANEKTTLFPAEPTEN-RERTANEKTTSSPAEPTENGQRTPFANEKTTS 695

Query: 394  --VSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEP 451
                P  H +   LA+ + ++ P   + T   E +A   T+    E T     + N+   
Sbjct: 696  SSAEPTEHGERTPLANENTTLSP--AEPTENRERTANEKTTPFPAEPTENRERTANENTT 753

Query: 452  PAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGES 511
            P+      P  P  + +  PLA  ++T+    EP  N   +P   E             S
Sbjct: 754  PS------PAQPTENGDRTPLA-NEKTTPSLAEPTENGKRTPFANEKTT---------SS 797

Query: 512  SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            S    E   +TP       + P E +   + T       F   P    E   +      P
Sbjct: 798  SAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTANEKTTPFP 857

Query: 572  TQPPKKVVPQLRVYQGVTNPT--PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
             +P +      R +    N T  P +      ++P     L +   T++P   TE G  T
Sbjct: 858  AEPTEN-----REWTANENTTLSPAEPTEHEEMTP-----LANEKTTLSPAEPTENGERT 907

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT 689
            P      +P   E T  H ++    +   T +  +P + G  I  +  T         + 
Sbjct: 908  PFTNEKTTPSSAEPT-EHGERTPLANEITTPSRAEPTEHGERIANEKATP--------SP 958

Query: 690  APPPGHPEVTL----PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
            A P  H E T+     PS     ++   T     PL  E T TT PT   +    T    
Sbjct: 959  AKPTEHGETTVNEDTTPSSAEPTENGERT-----PLANENT-TTSPTESTEHGERTANEK 1012

Query: 746  TQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
            T P         EPT     + +  + T P P +  T H  +T      T   P + +  
Sbjct: 1013 TTPSP------AEPTEHGERTPSANEKTIPSPAK-PTEHEEMTPSANENTTPSPVKPTEH 1065

Query: 806  QSESYTQNKALT----APEEHKASTST 828
              ++   N+ +T     P EH A T++
Sbjct: 1066 GEKTTLANEKITLSPEGPTEHGAKTTS 1092



 Score = 78.6 bits (192), Expect = 5e-14
 Identities = 150/707 (21%), Positives = 240/707 (33%), Gaps = 98/707 (13%)

Query: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           Q +  ST  P   +   +   K+   P  SE+   S+  +  +    +T ++IQ +    
Sbjct: 217 QTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISAN 276

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           E    L +  E    +  +     P E +       N   ++ P    +      N    
Sbjct: 277 ELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPIENRERTANENTA 336

Query: 301 PADVEVTITSEPTNETESSQAQQET--PIQFPEEVEPSATQQEAPIEPPVPPMEH-ELSI 357
           P        + PT   E +  +  T  P +  E  E +A +   P   P  P EH E + 
Sbjct: 337 P------FPAGPTENREMTANENTTLFPAEPTEHGERTANENTTP--SPAEPTEHGERTA 388

Query: 358 SEQQ--QPVQPSE--------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
           +E     P +P+E        + +   SS    E   + P  +E T   P     +   +
Sbjct: 389 NENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERT 448

Query: 408 PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
            + +  P     T   E +A   T+L   E T     + N+   P+      P  P  + 
Sbjct: 449 ANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPS------PAEPTENG 502

Query: 468 EAGPLAVQQETSFQSPE-------PINNENPSPTQQEAAAEHPQTAEEGE--SSLTHQEA 518
           +  P A ++ TS  +         P+ NEN +P+  E      +TA E    S     E 
Sbjct: 503 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 562

Query: 519 PAQTP---EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
             +TP   E     +A+P E+   T    +      + + E     E +P   E  T  P
Sbjct: 563 GDRTPLANEKTTPSLAEPTENGQRTPFANEKTT---SSSAEPTEHEERTPLANENTTPSP 619

Query: 576 KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLL-DLGLTITPEPTTEVGHSTPPKRT 634
            +     R      N TP       P  P+   ++  +   T+ P   TE    T  ++T
Sbjct: 620 AEPTEN-RERTANENTTPS------PAGPTENREMTANEKTTLFPAEPTENRERTANEKT 672

Query: 635 IVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLG---------FTITPKSMTEVEPSTA 685
             SP  P     +  +    +   T ++ +P + G          T++P   TE    TA
Sbjct: 673 TSSPAEPT---ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAEPTENRERTA 729

Query: 686 LMTTAPPPGHP---------EVTLP----PSDKGQAQ---HSHLTQATVQPLD--LELTI 727
              T P P  P         E T P    P++ G      +   T +  +P +       
Sbjct: 730 NEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPF 789

Query: 728 TTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTT----APRPDRVQTL 783
             + TT     PT     T   +      P   TE R  TA EKTT     P  +R  T 
Sbjct: 790 ANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 849

Query: 784 HRSLTEVTGPPTELEPAQDSLVQSESYTQNKALT----APEEHKAST 826
           +   T     PTE          +  +T N+  T     P EH+  T
Sbjct: 850 NEKTTPFPAEPTE----------NREWTANENTTLSPAEPTEHEEMT 886



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 82/346 (23%), Positives = 139/346 (40%), Gaps = 47/346 (13%)

Query: 78   PADPWDFDHLGPSASSEMPAPPQESTEN--LVPFLD--TWDSAGEQPLEPEQF-LASQQD 132
            PA+P + + + P A+ +    P E TEN    PF +  T  S+ E     E+  LA++  
Sbjct: 876  PAEPTEHEEMTPLANEKTTLSPAEPTENGERTPFTNEKTTPSSAEPTEHGERTPLANEIT 935

Query: 133  LKDKLSPQER-LPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT-------LQNEY 184
               +  P E    ++ +K    PA+     E      + +TP S + T       L NE 
Sbjct: 936  TPSRAEPTEHGERIANEKATPSPAKPTEHGET--TVNEDTTPSSAEPTENGERTPLANE- 992

Query: 185  SSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPA 244
            ++T +P   +   E        P P+E   P++      + N +T+           +PA
Sbjct: 993  NTTTSPTESTEHGERTANEKTTPSPAE---PTEHGERTPSANEKTI----------PSPA 1039

Query: 245  QLPQLLEEEPSSMQQEAPA-LPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKP 301
            +  +  E  PS+ +   P+ + P    E  TL N ++++ P  P E  A     N  + P
Sbjct: 1040 KPTEHEEMTPSANENTTPSPVKPTEHGEKTTLANEKITLSPEGPTEHGAKTTSANEKITP 1099

Query: 302  ADVEVTITSEPT---NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEH----E 354
            +  + T   E T   N+  +S A + T      E    AT        P  P++H     
Sbjct: 1100 SLAKPTEHGERTTSPNDKITSSAAEST------EHRDRATSANVITPAPAEPIKHAKRTT 1153

Query: 355  LSISEQQQPVQPSESPREVESSPTQQ--ETPGQPPEHHEVTVSPPG 398
            L+  +  Q  + S    E  +S T++   TP +P  + E T+   G
Sbjct: 1154 LAHEKMTQVTEKSTEHPEKTTSTTEKTTRTPEKPTLYSEKTICTKG 1199



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 69/333 (20%), Positives = 117/333 (35%), Gaps = 51/333 (15%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +             
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGK------------- 155

Query: 535 EHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG 594
              H+T A            P+SK     S T K T T+   K    L       + T  
Sbjct: 156 --KHITPA------------PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTST 201

Query: 595 QDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
                   S   T    + G + T + +T    S P K T  S    + T    +  +T+
Sbjct: 202 S-------SHKTTTSFHNSGNSQTKQKST----SFPEKITAASKTTYKTTGTPEESEKTE 250

Query: 655 HSHLTRATVQPL-----DLGFTITPKSMTE--VEPSTALMTTAPPPGHPEVTLPPSDKGQ 707
            S  T A+ + L     ++  TI+   +T+   EP+     TA     P    P  ++ +
Sbjct: 251 DSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRER 310

Query: 708 AQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHST 767
             + + T +  +P++       + T      PT  E      +    + P   TE    T
Sbjct: 311 TANENTTLSPAEPIENRERTANENTAPFPAGPT--ENREMTANENTTLFPAEPTEHGERT 368

Query: 768 ALEKTTAPRPDRVQTLHRSLTEVTGP----PTE 796
           A E TT    +  +   R+  E T P    PTE
Sbjct: 369 ANENTTPSPAEPTEHGERTANENTTPSPAEPTE 401


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 110/460 (23%), Positives = 164/460 (35%), Gaps = 65/460 (14%)

Query: 382  TPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            +PG PP           H  T     P    +PP    T  A P+   G S         
Sbjct: 969  SPGSPPTLRV-------HGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS--------- 1012

Query: 442  LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP--TQQEAA 499
               S     P         L P S+  +   +   +TS  +P+P +  NP    T  + A
Sbjct: 1013 --ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFA 1070

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT 559
               P ++     +LT + +P   P  P  + + P   S +T           +++P S+ 
Sbjct: 1071 LSTPDSSVV--PALTPEPSPTPLPTLPKELTSDPSTPSEVT-----------SLSPTSE- 1116

Query: 560  EVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
            +V  S T  +  T P    V +   Y    +P+P       P        +  L  T+TP
Sbjct: 1117 QVPESDTTPDLDTTPYSSTVSE---YSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTP 1173

Query: 620  E-PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PTT    +TP   TI         +P P       + +T +T+ P     T TP+  T
Sbjct: 1174 HFPTTPHPTTTPHPTTITH----STMIPDPTTTPQPFTTITHSTMIPDP---TTTPQPFT 1226

Query: 679  EVEPSTALMTTAPPPG---HPEV----TLPPSDKGQAQHSHLTQATVQPLDLELTITTKP 731
             ++P+T   +T P P    HP      T+ P      Q     Q T  P     T T  P
Sbjct: 1227 TMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMP---HPTTTPHP 1283

Query: 732  TTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVT 791
            TT   P+ T   T+T  P +     P+PTT    +T  + TT P P         +    
Sbjct: 1284 TTTPHPTTTPHPTTTPHPTM----TPDPTTTPYPTTTPDPTTTPHPTTPDPSSTPVITTV 1339

Query: 792  GPPTEL-----EPAQDSLVQSESYTQNKALTAPEEHKAST 826
              PT L      P     V+   + Q    TAP  H +++
Sbjct: 1340 SLPTSLGTELSSPTLAPTVKPSLHPQ-LTFTAPAPHTSTS 1378



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 132/576 (22%), Positives = 195/576 (33%), Gaps = 98/576 (17%)

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G TR   +P + +  +  +  S   P+P   PP        PP PS     S     P  
Sbjct: 965  GTTRSPGSPPTLR--VHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPAL 1022

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP 284
             +  + E    S+L  EA +  P      P    +  P L   S   +L+ P+  V    
Sbjct: 1023 TSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSV---- 1078

Query: 285  PGEDQAYYHLPNITVKPADVEV-TITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEA 342
                     +P +T +P+   + T+  E T++  +           P EV   S T ++ 
Sbjct: 1079 ---------VPALTPEPSPTPLPTLPKELTSDPST-----------PSEVTSLSPTSEQV 1118

Query: 343  PIEPPVPPME---HELSISEQQQPVQPSESPREVES-SPTQQE----------TPGQPPE 388
            P     P ++   +  ++SE  +   PS SP    +  PT             TP  P  
Sbjct: 1119 PESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT 1178

Query: 389  HHEVTVSPPGHHQTHHLASPSVSVKPPD----VQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             H  T +P     TH    P  +  P         T+  +P+         Q  TT  S 
Sbjct: 1179 PHP-TTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237

Query: 445  SGNDV---EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501
            + +      P  I H    ++P+ +    P    Q T+   P P    +P+ T       
Sbjct: 1238 TPHPTTTPHPTTITHS--TMIPDPTTTPQPFTTMQPTTM--PHPTTTPHPTTTPHPTTTP 1293

Query: 502  HPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
            HP T        T    P  TP +P      P    H T        +  T++  +    
Sbjct: 1294 HPTTTPHP----TMTPDPTTTP-YP-TTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGT 1347

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            ELS     +PT  P  V P L      T P P    +Q P              T+ P P
Sbjct: 1348 ELS-----SPTLAP-TVKPSLHPQLTFTAPAPHTSTSQIP--------------TLEPSP 1387

Query: 622  TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE-- 679
              E   S     T + P   E   P     ++Q  +LT           T TP S ++  
Sbjct: 1388 ALESSPSRSSTATSMDPLSTEDFKP----PRSQSPNLTPPP--------THTPHSASDLT 1435

Query: 680  VEPSTALMTTAPPPGHP---EVTLPPSDKGQAQHSH 712
            V P   L  TA P  HP    +TL P+  GQ+   H
Sbjct: 1436 VSPDPLLSPTAHPLDHPPLDPLTLGPT-PGQSPGPH 1470



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 122/602 (20%), Positives = 181/602 (30%), Gaps = 124/602 (20%)

Query: 56   PPDSWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPP--QESTENLVPFLD-- 111
            P   W       P  +  AP  P+        GPSAS   P P    +S+  L P     
Sbjct: 985  PRKPWPERRPPRPAATRTAPPTPSP-------GPSASPGPPGPALTSDSSRELTPHSALT 1037

Query: 112  ---TWDSAGEQPLEPEQFLASQQDL----------------KDKLSPQER---LPVSPKK 149
               T D+    P  P+    +  DL                   L+P+     LP  PK+
Sbjct: 1038 SEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKE 1097

Query: 150  LKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGP 209
            L  DP+    +  +   + Q+    +        YSST + Y  S  P         P P
Sbjct: 1098 LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP------SPSPHP 1151

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
            +    P+       T NP       ++      P          P+++        P ++
Sbjct: 1152 TTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTP---------HPTTITHSTMIPDPTTT 1202

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
             +  T   H   +  P         P  T++P     + T  PT     +     T I  
Sbjct: 1203 PQPFTTITHSTMIPDPTTTPQ----PFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPD 1258

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEH 389
            P       T  +    P      H  +         P+ +P      PT    P   P  
Sbjct: 1259 PTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPH-----PTMTPDPTTTP-- 1311

Query: 390  HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV 449
                 + P    T H  +P  S  P    +T  + P++ +GT L                
Sbjct: 1312 --YPTTTPDPTTTPHPTTPDPSSTP---VITTVSLPTS-LGTEL---------------- 1349

Query: 450  EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEG 509
                     P L P       P     + +F +P P  + +  PT + + A     +   
Sbjct: 1350 -------SSPTLAPTVKPSLHP-----QLTFTAPAPHTSTSQIPTLEPSPA---LESSPS 1394

Query: 510  ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKE 569
             SS      P  T +F        P  S     T  P     T TP S +++ +SP    
Sbjct: 1395 RSSTATSMDPLSTEDF-------KPPRSQSPNLTPPP-----THTPHSASDLTVSPDPLL 1442

Query: 570  TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
            +PT  P    P   +  G   PTPGQ    H             G  + P P   V    
Sbjct: 1443 SPTAHPLDHPPLDPLTLG---PTPGQSPGPH-------------GPCVAPTPPVRVMACE 1486

Query: 630  PP 631
            PP
Sbjct: 1487 PP 1488



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 36/139 (25%)

Query: 674 PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
           PKS  +     A   T  PP      +P +   +AQ          P DL    T   TT
Sbjct: 625 PKSTKKWVTKNAKRPTTQPP-----VMPTTKHSRAQ---------SPPDLTSQTTAALTT 670

Query: 734 EVKPSPTTEETSTQPPDLGLAIIPEPTTE-----TRHSTALEKTTAPRPDRVQTLHRSLT 788
           E    PT+E T              PTTE     T H+TA     APR    +T+    T
Sbjct: 671 EASRRPTSEFTR------------RPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTT 718

Query: 789 EVTGPPTELEPAQDSLVQS 807
           +  GP    E   +S ++S
Sbjct: 719 Q--GPQ---EMTSESTIKS 732


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 85.1 bits (209), Expect = 5e-16
 Identities = 167/735 (22%), Positives = 232/735 (31%), Gaps = 109/735 (14%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3784

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3785 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3828

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3829 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3879

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3934

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4104

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4105 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4151

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSH----LTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               I +      T P P   QT  +      T  T  P   G    P + T   P   L 
Sbjct: 4152 TTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210

Query: 688  TTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ----PLDLELTITTKPTTEVKPSPTTEE 743
            T+ PPP   E + P + +  +  S LT++T      P  +E+T T  P+T   P+ T+  
Sbjct: 4211 TSNPPP---ESSTPQTSRSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGG 4265

Query: 744  TSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPP--------- 794
             +  PP         P T TR  T    ++AP P  VQT   S    T  P         
Sbjct: 4266 HTLSPPP--STTTSPPGTPTR-GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322

Query: 795  TELEPAQDSLVQSESYTQNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLR 853
            T L P   S++       N    AP EE    T  + C    C    LSC          
Sbjct: 4323 TGLRPYPSSVL--ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCP 4377

Query: 854  QVPVPEPNTHNGTFT 868
              P P P     T T
Sbjct: 4378 STPSPTPTPSKSTPT 4392



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 128/501 (25%), Positives = 158/501 (31%), Gaps = 109/501 (21%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P D  +T  S PT           T    P    PS         PP       ++ +  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTT---LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
              P      P    ++P    TP  P      T SPP    T   + P+ +   P    T
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPT----TTPSPP----TTTPSPPTTTTTTPPPTTT 1499

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
                PS    T +    +TT L  +     P       PP    S     P+     TS 
Sbjct: 1500 ----PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT--PPTST 1553

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
             +  P    +P PT                   T    P  TP  P      PP    +T
Sbjct: 1554 TTLPPTTTPSPPPTT------------------TTTPPPTTTPSPPTTTTPSPPT---IT 1592

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
              T  P     T TP        SP    T T PP             T P+P       
Sbjct: 1593 TTTPPP-----TTTP--------SPPTTTTTTPPP------------TTTPSP---PTTT 1624

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P++P  +   L    T +P PTT    +TPP  T  SP  P  T P P         +T 
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTT---TTPPPTTTPSP--PTTTTPSPP--------ITT 1671

Query: 661  ATVQPLDLGFTITPKS--MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
             T  P     T TP S   T   P T  MTT      P  T  PS       S +T  T 
Sbjct: 1672 TTTPPP----TTTPSSPITTTPSPPTTTMTT------PSPTTTPS-------SPITTTTT 1714

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPD 778
                   T +  PTT   PSPT   T+  PP   +  +P PTT     T+   TT P P 
Sbjct: 1715 P--SSTTTPSPPPTTMTTPSPT---TTPSPPTTTMTTLP-PTT-----TSSPLTTTPLPP 1763

Query: 779  RVQTLHRSLTEVTGPPTELEP 799
             +     S    T P T   P
Sbjct: 1764 SITPPTFSPFSTTTPTTPCVP 1784



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 92/372 (24%), Positives = 121/372 (32%), Gaps = 35/372 (9%)

Query: 459  PPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
            PP  P S+    P       +  +  P     PSP         P T      S T    
Sbjct: 1408 PP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 519  PAQTPEFPNVVVAQP---PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKET---PT 572
            P  TP  P    + P   P     T  T  P     T TP   T   ++P    T   PT
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP-----TTTPSPPTTTPITPPASTTTLPPT 1520

Query: 573  QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---ST 629
              P             T P+P       P++P  +   L    T +P PTT       +T
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT- 688
            P   T  +P  P +T   P    T     T  T  P     T +P + T + P T+  T 
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTL 1635

Query: 689  ---TAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
               T P P     T PP     +  +     T  P     T TT P T    SP T  T+
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPT-----TTTPSPPITTTTTPPPTTTPSSPIT--TT 1688

Query: 746  TQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
              PP   +   P PTT    S+ +  TT P      +   +      P T   P   ++ 
Sbjct: 1689 PSPPTTTMTT-PSPTTTP--SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745

Query: 806  QSESYTQNKALT 817
                 T +  LT
Sbjct: 1746 TLPPTTTSSPLT 1757



 Score = 76.3 bits (186), Expect = 2e-13
 Identities = 82/289 (28%), Positives = 98/289 (33%), Gaps = 30/289 (10%)

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQ 581
            TP  P    + PP  +     T  P     T T    T     P    T T PP    P 
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT--TTTTPPPTTTPS 1455

Query: 582  LRVYQGVTNP-TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH 640
              +    T P T          SP  T        T TP PTT     +PP  T ++P  
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITPPA 1512

Query: 641  PEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT----TAPPPGHP 696
               TLP      T     T  T  P     T +P + T + P T+  T    T P P   
Sbjct: 1513 STTTLP---PTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 697  EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAII 756
              T PP     +  +     T  P    +T TT P T   PSP T  T+T PP       
Sbjct: 1568 TTTTPPPTTTPSPPT-----TTTPSPPTITTTTPPPTTT-PSPPTTTTTTPPP----TTT 1617

Query: 757  PEPTTET-----RHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA 800
            P P T T       +T L  TT P P    T     T    PPT   P+
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 157/697 (22%), Positives = 213/697 (30%), Gaps = 113/697 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3715

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3716 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3759

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3760 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3810

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3865

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3921

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3922 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3981

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4035

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4036 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4082

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 4083 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 4131

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
                  VT  P+  G          T  P    +T TT  T    P+PT  +T T  P  
Sbjct: 4132 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTP-- 4177

Query: 752  GLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYT 811
                I   TT T   T     T P P    T   +    + PP E    Q S   S   T
Sbjct: 4178 ----ITTTTTVTPTPTPTGTQTGP-PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 812  QNKALTA---PEEHKAST---STNICELCTCGDEMLS 842
            ++  L +   P     ST   ST      T G   LS
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2027 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2082

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2083 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2126

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2127 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2177

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2178 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2232

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2233 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2288

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2289 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2402

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2403 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2449

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2450 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2498

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 2499 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2546

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2606

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2607 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2658

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2659 PITTTTTVT 2667



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2165 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2220

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2221 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2264

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2265 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2315

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2316 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2370

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2426

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2427 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2486

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2487 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2540

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2541 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2587

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2588 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2636

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 2637 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2684

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2744

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2745 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2796

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2797 PITTTTTVT 2805



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2303 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2358

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2359 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2402

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2403 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2453

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2454 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2508

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2509 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2564

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2565 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2624

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2625 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2678

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2679 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2725

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2726 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2774

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 2775 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2822

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2882

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2883 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2934

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2935 PITTTTTVT 2943



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2496

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2497 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2540

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2541 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2591

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2592 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2646

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2647 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2702

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2703 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2762

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2763 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2816

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2817 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2863

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2864 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2912

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 2913 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2960

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3020

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3021 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3072

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3073 PITTTTTVT 3081



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2634

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2635 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2678

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2679 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2729

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2784

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2954

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2955 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3001

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3002 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3050

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 3051 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3098

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3210

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3211 PITTTTTVT 3219



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2717 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2772

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2773 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2816

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2817 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2867

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2868 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2922

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2923 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2978

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2979 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3038

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3092

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3093 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3139

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3140 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3188

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 3189 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3236

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3296

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3297 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3348

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3349 PITTTTTVT 3357



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2855 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2910

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2911 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2954

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2955 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3005

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3006 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3060

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3061 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3116

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3117 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3176

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3177 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3230

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3231 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3277

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3278 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3326

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 3327 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3374

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3434

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3435 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3486

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3487 PITTTTTVT 3495



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2993 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3048

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3049 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3092

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3093 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3143

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3144 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3198

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3199 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3254

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3255 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3314

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3315 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3368

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3369 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3415

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3416 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3464

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 3465 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3512

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3572

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3573 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3624

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3625 PITTTTTVT 3633



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3186

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3187 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3230

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3231 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3281

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3282 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3336

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3337 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3392

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3393 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3452

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3453 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3506

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3507 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3553

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3554 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3602

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT T+  +T P  
Sbjct: 3603 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3650

Query: 751  LGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3710

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3711 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3762

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3763 PITTTTTVT 3771



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 161/734 (21%), Positives = 225/734 (30%), Gaps = 120/734 (16%)

Query: 167  TRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQN 226
            T   +T ++         ++T T  P   P   +  +  P   +  V P+       TQ 
Sbjct: 1884 TMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQT 1941

Query: 227  PETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPG 286
            P T             P      +   P+    + P   P ++  ++T        Q P 
Sbjct: 1942 PTT------------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP- 1988

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
                       T  P     T+T  PT     +Q    TPI     V P+ T       P
Sbjct: 1989 -----------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-P 2034

Query: 347  PVPPMEHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPP 397
               P+    +++    P     P+ +P    ++      PT  +TP   P     TV+P 
Sbjct: 2035 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP- 2093

Query: 398  GHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHG 457
                T            P    T         GT    Q  TT    +   V P     G
Sbjct: 2094 ----TPTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTG 2145

Query: 458  G--PPLLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEG 509
               P   P  ++    P      T   +  PI         P+PT  +     P T    
Sbjct: 2146 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT 2205

Query: 510  ESSL---THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPT 566
             +     T  + P  TP      V   P  +     T  P+    T+TP        +PT
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPT 2259

Query: 567  MKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVG 626
              +TPT  P      +        PTP     Q P +  +T        T+TP PT   G
Sbjct: 2260 GTQTPTTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TG 2306

Query: 627  HSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
              TP    I +      T P P   QT        T  P+    T+TP   T     T  
Sbjct: 2307 TQTPTTTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQT 2355

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETS 745
             TT P      VT  P+  G          T  P    +T TT  T    P+PT T+  +
Sbjct: 2356 PTTTPITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPT 2403

Query: 746  TQPPDLGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPP 794
            T P      + P PT   T+T  +T +  TT     P P   QT       + T VT  P
Sbjct: 2404 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2463

Query: 795  TELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQ 854
            T       +     + T       P   +  T+T I    T        +   P     Q
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQ 2515

Query: 855  VPVPEPNTHNGTFT 868
             P   P T   T T
Sbjct: 2516 TPTTTPITTTTTVT 2529



 Score = 68.2 bits (165), Expect = 7e-11
 Identities = 131/594 (22%), Positives = 190/594 (31%), Gaps = 95/594 (15%)

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
            I V+  +     T+  T  TE+      TPI     V P+ T       P   P+    +
Sbjct: 1871 INVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTT 1929

Query: 357  ISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            ++    P     P+ +P    ++      PT  +TP   P     TV+P          +
Sbjct: 1930 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT--------PT 1981

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
            P+ +  P    +T     +     +      TT ++ +      P          P  ++
Sbjct: 1982 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT---------PTGTQ 2032

Query: 468  EAGPLAVQQETSFQ-SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP 526
                  +   T+   +P P   + P+ T          T        T  + P  TP   
Sbjct: 2033 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-----TGTQTPTTTPITT 2087

Query: 527  NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
               V   P  +     T  P+    T+TP        +PT  +TPT  P      +    
Sbjct: 2088 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTPITTTTTV---- 2137

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP 646
                PTP     Q P +  +T        T+TP PT   G  TP    I +      T P
Sbjct: 2138 ---TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPTTTPITTTTTVTPT-P 2187

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
             P   QT        T  P+    T+TP   T     T   TT P      VT  P+  G
Sbjct: 2188 TPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPTPTG 2237

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT-TEETSTQPPDLGLAIIPEPT---TE 762
                      T  P    +T TT  T    P+PT T+  +T P      + P PT   T+
Sbjct: 2238 ----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2285

Query: 763  TRHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEPAQDSLVQSESYTQNK 814
            T  +T +  TT     P P   QT       + T VT  PT       +     + T   
Sbjct: 2286 TPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2345

Query: 815  ALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
                P   +  T+T I    T        +   P     Q P   P T   T T
Sbjct: 2346 PTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2391



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 160/745 (21%), Positives = 226/745 (30%), Gaps = 94/745 (12%)

Query: 170  LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
            ++TP     T     +ST T  P + P      +  PP  +    PS       T  P T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPITTTTTPPPTT 1452

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289
                  S+     P   P      P +     P   P     + T P    +  PP    
Sbjct: 1453 TPSPPISTTTTPPPTTTPS-----PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 290  -----AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI 344
                 +   LP  T        T T  PT           TP      + P+ T    P 
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 345  EPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
                PP       +    P   + SP  + ++     T   PP     T +PP    T  
Sbjct: 1568 TTTTPP-----PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT--TTTTTPP--PTTTP 1618

Query: 405  LASPSVSVKPPDVQLTI--AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
                +  + PP    T+     PS    T+      TT          PP      PP+ 
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT--------PSPPTTTTPSPPIT 1670

Query: 463  PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
              ++           T+  SP       PSPT   ++   P T     SS T    P  T
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS---PITTTTTPSSTTTPSPPPTT 1727

Query: 523  PEFPNVVVAQPPEHSHLT--QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVP 580
               P+      P  + +T    T     L  T  P S T    SP    TPT P    VP
Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP---CVP 1784

Query: 581  QLRVYQGVTNPTP------GQDQAQHPVSPSVTVQLLDLGLTITPE-PTTEVGHSTPPKR 633
                   + +  P      G  +    V        +    T+ P+ P  ++G +     
Sbjct: 1785 LCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDV 1844

Query: 634  TI-----VSPKHPEVTLPHPDQVQTQ-HSHLTRATVQPLDLGFTIT----PKSMTEVEPS 683
            ++        + P   +P    +  + +        QP  +  T T    P + T +  +
Sbjct: 1845 SVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTT 1904

Query: 684  TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL---TITTKP---TTEVKP 737
            T +  T  P G    T  P           T  TV P        T TT P   TT V P
Sbjct: 1905 TTVTPTPTPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETRHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2067

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVT 2092



 Score = 39.7 bits (91), Expect = 0.025
 Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 10/111 (9%)

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDR 779
            P+D  +T  + PTT   P PT+  T+T PP       P P T T  +T    TT P P  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTS--TTTLPP----TTTPSPPTTT--TTTPPPTTTPSPPI 1442

Query: 780  VQTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
              T     T    PP  T   P   +     + T +   T P     +T+T
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 84.3 bits (207), Expect = 9e-16
 Identities = 163/743 (21%), Positives = 233/743 (31%), Gaps = 125/743 (16%)

Query: 154  PAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPY-PGSLPPEL-RVKSDEPPGPSE 211
            P Q W +         LS+      +     S T TP  P +L        S EPP P+ 
Sbjct: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276

Query: 212  QVGPSQFHLEPET---QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             V P      P T   ++  T   +  ++ +  A    P       S+ +       P +
Sbjct: 1277 AVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPAT 1336

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTIT---SEPTNETESSQAQQET 325
            S  S TLP    + + PG        P  T  PA      T    +PT  T +   Q  T
Sbjct: 1337 SGTSPTLPK-STNQELPGTTATQTTGPRPT--PASTTGPTTPQPGQPTRPTATETTQTRT 1393

Query: 326  PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSES------PREVESSPTQ 379
              ++     P  T        PVP      + S       P+ S      P  V    T 
Sbjct: 1394 TTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453

Query: 380  QETPGQ----PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVH 435
              TP       P H ++  S   H        P  ++K      T         GTS  H
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP-----------LAVQQETSFQSPE 484
               +T  + +       +  H  P + P S+    P                 TS + P 
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHH--PEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP 1571

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTH-------QEAPAQTPEF------PNVVVA 531
            P    +P       ++  P TA   +++ T+          P   P F      P+    
Sbjct: 1572 PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV 1631

Query: 532  QPPEHSHL-TQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
              P H+ + T A++  +  G TI P    ++      +PTM  T T    + +  L   +
Sbjct: 1632 ITPTHAQMATSASIHSMPTG-TIPPPTTLKATGSTHTAPTMTLT-TSGTSQALSSLNTAK 1689

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIV---------- 636
              T+         H  + S +         ITP PT+     TPP               
Sbjct: 1690 TSTSLHSHTSSTHHAEATSTST------TNITPNPTST---GTPPMTVTTSGTSQSRSSF 1740

Query: 637  --------------SPKHPEVTLPHPDQVQTQH---------SHLTRATVQPLDLGFT-- 671
                          S  HPEVT      +   H         +H T AT   L   FT  
Sbjct: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800

Query: 672  -----ITPKSMTEVEPSTALMTTA--PPPGHPEVTLP------------PSDKGQAQHSH 712
                  TP S T    +T+  TT   P P HP  TLP            PS       +H
Sbjct: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860

Query: 713  LTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKT 772
               AT   +    T T  P T +K    T  T T PP   +      T+++  S +  KT
Sbjct: 1861 TQMATSASIHSMPTGTIPPPTTIK---ATGSTHTAPP---MTPTTSGTSQSPSSFSTAKT 1914

Query: 773  TAPRPDRVQTLHRSLTEVTGPPT 795
            +   P    + H    EVT   T
Sbjct: 1915 STSLPYHTSSTHH--PEVTPTST 1935



 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 154/717 (21%), Positives = 243/717 (33%), Gaps = 139/717 (19%)

Query: 144  PVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKS 203
            P  P+         +S + +   T  + TP   +        S  T   G++PP   +K+
Sbjct: 1436 PSHPETTLPTHVPPFSTSLVTPSTHTVITPTHAQMATSASNHSAPT---GTIPPPTTLKA 1492

Query: 204  D-----EPPGPSEQVGPSQFHLEPET-QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSM 257
                   PP      G SQ H    T + P +L    SS+   E        +   P+S 
Sbjct: 1493 TGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTST 1552

Query: 258  QQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETE 317
            +   P     S+  S   P       P G        P  +  P    +T TS  T  T 
Sbjct: 1553 RTRTPVAHTNSATSSRPPPPFTTHSPPTGSS------PFSSTGP----MTATSFKTTTTY 1602

Query: 318  SSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSP 377
             + +  +T +  P  V P +T         V P  H +        + P+ +     +S 
Sbjct: 1603 PTPSHPQTTL--PTHVPPFSTSL-------VTPSTHTV--------ITPTHAQMATSASI 1645

Query: 378  TQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQE 437
                T   PP     T+   G   T    +P++++        +++  +A+  TSL    
Sbjct: 1646 HSMPTGTIPPP---TTLKATGSTHT----APTMTLTTSGTSQALSSLNTAKTSTSLHSHT 1698

Query: 438  ATTR----LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
            ++T      S S  ++ P     G PP+   +S  +     Q  +SF + +     + S 
Sbjct: 1699 SSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTS-----QSRSSFSTAKT----STSL 1749

Query: 494  TQQEAAAEHPQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF 551
                ++  HP+      +S+T  H     +TP             +H T AT   L   F
Sbjct: 1750 HSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV------------AHTTSATSSRLPTPF 1797

Query: 552  TITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN-PTPGQDQAQHPVS-PSVTVQ 609
            T          +S T   T T            +Q  T  PTP       P   PS +  
Sbjct: 1798 TTHSPPTGTTPISSTGPVTATS-----------FQTTTTYPTPSHPHTTLPTHVPSFSTS 1846

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKH------------PEVTLPHPDQVQTQHSH 657
            L+                 TP   T++ P H            P  T+P P  ++   S 
Sbjct: 1847 LV-----------------TPSTHTVIIPTHTQMATSASIHSMPTGTIPPPTTIKATGST 1889

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQAT 717
             T   + P   G + +P S +  + ST+L        HPEVT  P+        H +  T
Sbjct: 1890 HTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTTNITPKHTSTGT 1947

Query: 718  VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTA-PR 776
              P    +  TT  ++   P+P T    T  P  G +  P  +T    +T+ + TT  P 
Sbjct: 1948 RTP----VAHTTSASSSRLPTPFT----THSPPTGSS--PFSSTGPMTATSFQTTTTYPT 1997

Query: 777  PDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESY-----TQNKALTAPEEHKASTST 828
            P   QT           PT + P   SLV   ++     T  +  T+   H   T T
Sbjct: 1998 PSHPQTT---------LPTHVPPFSTSLVTPSTHTVIITTHTQMATSASIHSTPTGT 2045



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 116/566 (20%), Positives = 184/566 (32%), Gaps = 101/566 (17%)

Query: 325  TPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
            T I       PS +    P  P   P+      S +  P   S  P    ++ T Q T G
Sbjct: 1228 TTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSK--PTASSGEPPRPTTAVTPQATSG 1285

Query: 385  QPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             PP                     S + KP   Q T  A  S     +    ++TTR + 
Sbjct: 1286 LPPT----------------ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTM 1329

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
            +     P     G  P LP+S+ +  P     +T+   P P            A+   P 
Sbjct: 1330 T----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTP------------ASTTGPT 1373

Query: 505  TAEEG--------ESSLTHQEAPAQTPEFPNVVVAQP----------------------- 533
            T + G        E++ T       TP+ P+   + P                       
Sbjct: 1374 TPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433

Query: 534  --PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P H   T  T  P      +TP + T +  +PT  +  T       P   +    T  
Sbjct: 1434 PTPSHPETTLPTHVPPFSTSLVTPSTHTVI--TPTHAQMATSASNHSAPTGTIPPPTTLK 1491

Query: 592  TPGQDQAQHPVSPSVT-VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
              G      P++P+ +         +    PT+   H++      V+P       P+P  
Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 651  VQTQH--SHLTRATVQPLDLGFTI-------TPKSMTEVEPSTALMTTA--PPPGHPEVT 699
             +T+   +H   AT       FT        +P S T    +T+  TT   P P HP+ T
Sbjct: 1552 TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 700  LP-------PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG 752
            LP        S    + H+ +T    Q +    +I + PT  + P  T + T +      
Sbjct: 1612 LPTHVPPFSTSLVTPSTHTVITPTHAQ-MATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670

Query: 753  LAIIPEPTTETRHSTALEKTTAPRPDRVQTLHR------SLTEVTGPPTELEPAQDSLVQ 806
            + +    T++   S    KT+        + H       S T +T  PT       ++  
Sbjct: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730

Query: 807  S------ESYTQNKALTAPEEHKAST 826
            S       S++  K  T+   H +ST
Sbjct: 1731 SGTSQSRSSFSTAKTSTSLHSHTSST 1756



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 122/611 (19%), Positives = 211/611 (34%), Gaps = 89/611 (14%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            S+P S    +      T T YP    P+  + +  PP  +  V PS   +      P   
Sbjct: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI----TPTHA 1637

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN---HEVSVQPPGE 287
            +   S+S+       +P     + +     AP +   +S  S  L +    + S      
Sbjct: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697

Query: 288  DQAYYHLP-------NITVKPADV---EVTITSEPTNETESSQAQQETPIQFPE------ 331
              + +H         NIT  P       +T+T+  T+++ SS +  +T            
Sbjct: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757

Query: 332  --EVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP 386
              EV  ++T    P         P+ H  S +  + P   +       ++P     P   
Sbjct: 1758 HPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817

Query: 387  PEHHEVTVSP-PGHHQTH---HLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRL 442
                  T  P P H  T    H+ S S S+  P     I    +    ++ +H   T  +
Sbjct: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877

Query: 443  SGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH 502
                  ++     H  PP+ P +S  +     Q  +SF + +     + S     ++  H
Sbjct: 1878 PPP-TTIKATGSTHTAPPMTPTTSGTS-----QSPSSFSTAKT----STSLPYHTSSTHH 1927

Query: 503  PQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTI------- 553
            P+      +++T  H     +TP             +H T A+   L   FT        
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPV------------AHTTSASSSRLPTPFTTHSPPTGS 1975

Query: 554  TPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL 613
            +P S T   ++ T  +T T  P    PQ       T PT     +   V+PS    ++  
Sbjct: 1976 SPFSSTG-PMTATSFQTTTTYPTPSHPQ------TTLPTHVPPFSTSLVTPSTHTVIIT- 2027

Query: 614  GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT 673
              T T   T+   HSTP             T+P P  ++   S  T   +     G + T
Sbjct: 2028 --THTQMATSASIHSTPTG-----------TVPPPTTLKATGSTHTAPPMTVTTSGTSQT 2074

Query: 674  PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
              S +    S++ ++++        + PPS     Q  HL+ AT       ++ T + ++
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT-----PVSTTNQLSS 2129

Query: 734  EVKPSPTTEET 744
               PSP+   T
Sbjct: 2130 SFSPSPSAPST 2140


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 177/748 (23%), Positives = 276/748 (36%), Gaps = 135/748 (18%)

Query: 118 EQPLEPEQFLASQQD----LKDKLSPQERLPVSPK-KLKKDPAQRWSLAEIIGITRQLST 172
           E+ + PE+  A  ++    L + +   E  P  P  +LK D +Q+ S     G    ++ 
Sbjct: 89  EETVVPEEKSADVREAAIELPESVQDVEIPPNIPSVQLKMDRSQQTSRT---GYWTMMNI 145

Query: 173 PQSQK-QTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGP----SQFHLEPETQNP 227
           P  +K    Q  Y S       S P     KS E     +  G          +P T + 
Sbjct: 146 PPVEKVDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSN 205

Query: 228 ETL--EDIQSSSLQQEAPAQLPQLLEEEPSS-----MQQEAPALPPESSMESLTLPNHE- 279
           E +  ++I  +S  QE     P LLE+E        + QE  A+   +S E +  P+ E 
Sbjct: 206 EEIGQKNISRTSFTQETKKGPPVLLEDELREEVTVPVVQEGSAVKKVASAE-IEPPSTEK 264

Query: 280 --VSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPI--QFPEEVEP 335
               +QPP  ++A         +   V+V  ++E T + E++ A  E  +  Q P   E 
Sbjct: 265 FPAKIQPPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEA 324

Query: 336 SATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVS 395
              +  A I+PP       + +  +  P    ESP E    P  +  P  PP     +V 
Sbjct: 325 PLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSE---EPPAEILP--PPAEKSPSVE 379

Query: 396 PPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQ 455
             G      + SPS    P +VQ  + AE + E        EA  +       VEPP ++
Sbjct: 380 LLGE-----IRSPSAQKAPIEVQ-PLPAEGALE--------EAPAK-------VEPPTVE 418

Query: 456 H---GGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
                  PLLPE +       +Q  T+ ++P        +PT+ ++      TAEE  + 
Sbjct: 419 ETLADVQPLLPEEAPREEARELQLSTAMETPA-----EEAPTEFQSPLPKETTAEEASA- 472

Query: 513 LTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
                      E   +   +PP      +A   PL    T   E+  EV+ SP  +ET  
Sbjct: 473 -----------EIQLLAATEPPADETPAEAR-SPLSEE-TSAEEAHAEVQ-SPLAEETTA 518

Query: 573 QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPK 632
           +     +  L   +   + TP +  AQ P+S   + +          E   EV     P 
Sbjct: 519 EEASAEIQLLAAIEAPADETPAE--AQSPLSEETSAE----------EAPAEV---QSPS 563

Query: 633 RTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA-- 690
              VS +   + L  P   +T     + A +Q L        ++  EV+P  A    A  
Sbjct: 564 AKGVSIEEAPLELQPPSGEETTAEEAS-AAIQLLAATEASAEEAPAEVQPPPAEEAPAEV 622

Query: 691 -PPPGHP---EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETS 745
            PPP      EV  PP+++  A+        VQP   E     +   EV+P P  E    
Sbjct: 623 QPPPAEEAPAEVQPPPAEEAPAE--------VQPPPAE-----EAPAEVQPPPAEEAPAE 669

Query: 746 TQPP---DLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSL--------------- 787
            QPP   +    +   P  ET     L    +P  D V     S+               
Sbjct: 670 VQPPPAEEAPAEVQSLPAEETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEF 729

Query: 788 ------TEVTGPPTELEPAQDSLVQSES 809
                  EV+ PP+E  P  ++LV++ S
Sbjct: 730 PIGEASAEVSPPPSEQTPEDEALVENVS 757



 Score = 48.9 bits (115), Expect = 4e-05
 Identities = 86/339 (25%), Positives = 132/339 (38%), Gaps = 59/339 (17%)

Query: 92  SSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
           S+ M  P +E+       L    +A E   E  Q LA+ +   D+   + R P+S +   
Sbjct: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEI-QLLAATEPPADETPAEARSPLSEETSA 501

Query: 152 KD-------PAQRWSLAEIIGITRQL---------STPQSQKQTLQNEYSSTDTPYPGSL 195
           ++       P    + AE      QL          TP   +  L  E S+ + P     
Sbjct: 502 EEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561

Query: 196 PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL-PQLLEEEP 254
           P    V  +E P   +     +   E  +   + L   ++S+  +EAPA++ P   EE P
Sbjct: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA--EEAPAEVQPPPAEEAP 619

Query: 255 SSMQ----QEAPA--LPP---ESSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPAD 303
           + +Q    +EAPA   PP   E+  E    P  E    VQPP  ++A          PA+
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA----------PAE 669

Query: 304 VEVTITSEPTNETESSQAQQETPIQF--------PEEVEPSATQQEAPIEPPVPP----M 351
           V+     E   E +S  A +ETPI+         P +  P+   +EA ++   PP    +
Sbjct: 670 VQPPPAEEAPAEVQSLPA-EETPIEETLAAVHSPPADDVPA---EEASVDKHSPPADLLL 725

Query: 352 EHELSISEQQQPVQ--PSESPREVESSPTQQETPGQPPE 388
             E  I E    V   PSE   E E+      T  Q P+
Sbjct: 726 TEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 139/675 (20%), Positives = 242/675 (35%), Gaps = 122/675 (18%)

Query: 132   DLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPY 191
             ++ +K+ P ++ P      K+ PA+   + + I +  ++  P+  +           T  
Sbjct: 10444 EISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP--------PTKV 10495

Query: 192   PGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
             P  LPP+  V   + P P  +        +PE   P+  E  +    +++ P   P+  E
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAK--------KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 252   EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV--EVTIT 309
               P+ + +   A  PE  +     P  E    PP         P +   P +V  E  + 
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPE---SPP---------PEVPEAPKEVVPEKKVP 10595

Query: 310   SEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP----VPPME----HELSISEQQ 361
             + P  + E       TP++ PE  +    +++ P+ PP    VPP +     ++++ E++
Sbjct: 10596 AAPPKKPEV------TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649

Query: 362   Q----PVQPSESPREVESSPTQ---QETPGQPPEHHEVTVSP----PGHHQTHHLASPSV 410
                  P +P   P EV   P +   +E P +  E  E    P    P         +P+V
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709

Query: 411   SVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPE------ 464
               K P++      E   EV    V ++    +     +  P  +      ++PE      
Sbjct: 10710 VAKKPELPPVKVPEVPKEV----VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 465   SSEEAGPLAVQQETSFQSPEPINNENPS-PTQQEAAAEHPQTAEEGESSLTHQE------ 517
                E  P  V +       +P+  E P+ P  + A +  P+  EE E     +E      
Sbjct: 10766 KKPEVPPAKVPEVPK----KPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821

Query: 518   -----APAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
                  A  + PE P   V + P+                 I PE K      P +K+   
Sbjct: 10822 KPVPVAEEEEPEVPPPAVPEEPK----------------KIIPEKKV-----PVIKKPEA 10860

Query: 573   QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPK 632
              PPK+  P+  + +    P P       P  P   V+     L   P+         P K
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRP---PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 633   RTIVSPKHP----EVTLPHPDQVQTQHSHLTRATV---QPLDLGFTITPKSMTEVEPSTA 685
               +   K P    +V    P++       +   +V   +P +    + PK + +V+   A
Sbjct: 10918 VELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVK-KPA 10976

Query: 686   LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
             +    PP    EV +P   K + +    T+       + L     P  E KP P  E  +
Sbjct: 10977 VPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL-----PAPEPKPKPEAEVKT 11031

Query: 746   TQPPDLGLAIIPEPT 760
              +PP     + PEPT
Sbjct: 11032 IKPP----PVEPEPT 11042



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 161/792 (20%), Positives = 275/792 (34%), Gaps = 99/792 (12%)

Query: 122   EPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQ 181
             E E+F+  ++ L + + P+  +P    ++KK   ++      + I ++   P ++   + 
Sbjct: 10163 EEEEFVPEEEVLPE-VKPKVPVPAPVPEIKKKVTEKK-----VVIPKKEEAPPAKVPEVP 10216

Query: 182   NEYSSTDTPYPGS---LPPELRVKSDEPPGPSEQVG--PSQFHLEPETQNPETLEDIQSS 236
              +        P     LP E+  + +E P   E++   P       E   P   E I+ +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276

Query: 237   SLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPN 296
                 EAP  +P+ +E  P+ + ++ P       ++    P  +V   P    +    +P 
Sbjct: 10277 V--PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK 10334

Query: 297   ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIEPPVPPME--- 352
                 P     T+  E      S   +QE  ++   E+E   A  +E P E     +E   
Sbjct: 10335 KEAVPPAKGRTVLEEKV----SVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390

Query: 353   -----HELS--ISEQQQPVQPSESPREV-------ESSPTQQ-ETPGQPPEHHEVT--VS 395
                  HE+   I  +Q  V+      +V       E+   +  E P  PP+  E++  + 
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKII 10450

Query: 396   PPGHHQTHHLASPSVSVKPPDVQLTIAAE-----------PSAEVGTSLVHQEATTRLSG 444
             PP    T  +       K P+V   I  E           P  +V   L  +E       
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV 10510

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA-AEHP 503
                 V P       PP +PE+ +E  P     E     P P   E P     E   A  P
Sbjct: 10511 P---VPPAKKPEAPPPKVPEAPKEVVP-----EKKVPVPPPKKPEVPPTKVPEVPKAAVP 10562

Query: 504   QTAEEGESSLTHQEAPAQTPEFPNVVV------AQPPEHSHLTQATVQPLDLGFTITPES 557
             +           +  P + PE P  VV      A PP+   +T   V   +    + PE 
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVP--EAPKEVVPEK 10620

Query: 558   KTEVELSPTMKETPT---QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS-VTVQLLDL 613
             K  V      +  PT   + PK  VP+ +V + +  P P     +    P  V ++    
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPA 10679

Query: 614   GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTI- 672
              +   PEP      + PPK+ +   K P V    P+    +   + +  V    +   + 
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739

Query: 673   ---------TPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
                       P+   EV P   +        PP   PEV   P  + +       +A   
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESP 10799

Query: 720   PLDL-ELTITTKPTTEV-----KPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTT 773
             P ++ E      P  E+     KP P  EE   + P   +   P+     +    ++K  
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859

Query: 774   AP---RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL---TAPEEHKASTS 827
             AP    P+  + + +   +   PP    P ++ +   E   Q KA+     PE+ +    
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV--KEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 828   TNICELCTCGDE 839
               +  L   G E
Sbjct: 10918 VELTPLKVPGGE 10929



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 146/720 (20%), Positives = 251/720 (34%), Gaps = 88/720 (12%)

Query: 123   PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT-LQ 181
             PE+ + +    K+K+ P    P  P++ KK   ++    ++I +   L    +++   + 
Sbjct: 9589  PEKKVPAPVPKKEKVPP----PKVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQIT 9644

Query: 182   NEYSSTDTPYPGSLPPELRVKSDEPPG-PSEQVGPSQFHLEP--ETQNPETLEDIQSSSL 238
              E            PP+ RV  +     P E+V      L+P  E + P  + + +   +
Sbjct: 9645  QEEKVLVAVTKKEAPPKARVPEEPKRAVPEEKV----LKLKPKREEEPPAKVTEFRKRVV 9700

Query: 239   QQE-----APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
             ++E     AP + PQ ++E     ++E           + TL    VSVQ   E + Y  
Sbjct: 9701  KEEKVSIEAPKREPQPIKEVTIMEEKE----------RAYTLEEEAVSVQREEEYEEY-- 9748

Query: 294   LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEH 353
                   +  D +     EPT E +  +  +E   +  EE E   T+ E PI  PV P   
Sbjct: 9749  ------EEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPI--PVKP--- 9797

Query: 354   ELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK 413
                + E+  P +P   P +V      +E    P         P    +   +    + + 
Sbjct: 9798  ---VPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRIS 9854

Query: 414   PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA-IQHGGPPLLPE--SSEEAG 470
                 +     EP+A+V        A  ++     +V PP  +      L PE  + EE  
Sbjct: 9855  ITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEV 9914

Query: 471   PLAVQQETSFQSPEPINNENPSPTQQEAAAEHP-QTAEEGESSLTHQEAPAQTPEFPNVV 529
                V++    +  E I+ E    T++E     P +  E     +  ++ P   P+     
Sbjct: 9915  VTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAP 9974

Query: 530   VAQPPEHSHLTQATVQPL-------------DLGFTITPESKTEVELSPTMKETPT---Q 573
              A+ PE     +  V  L             ++     PE K  V +   ++  P    +
Sbjct: 9975  PAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE 10034

Query: 574   PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP-TTEVGHSTPPK 632
              PKK VP+ +    V  P P + +A     P V  +L+      TP P   E      PK
Sbjct: 10035 VPKKPVPEKK----VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPK 10090

Query: 633   RTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPP 692
             +    P    V LP  ++V  +   +    V P +       + +   E          P
Sbjct: 10091 KR--EPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIP 10148

Query: 693   PGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQP 748
             P   EV  P  +    +   + +  V P          P  E+K   T ++       + 
Sbjct: 10149 PEEEEVP-PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEA 10207

Query: 749   PDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSE 808
             P   +  +P+   E R     E+   P             EVT  P E EP  +  +  E
Sbjct: 10208 PPAKVPEVPKKVEEKRIILPKEEEVLP------------VEVTEEPEE-EPISEEEIPEE 10254



 Score = 59.3 bits (142), Expect = 3e-08
 Identities = 114/525 (21%), Positives = 190/525 (36%), Gaps = 88/525 (16%)

Query: 90    SASSEMPAPPQEST-ENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
             S   E+P  P+E   E  VP           P +PE       +   ++ P++++PV P 
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVP--------AAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPP 10627

Query: 149   KLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL-QNEYSSTDTPYPGSLPPEL-----RVK 202
             K  + P  +               P+  K  + + +      P P S PPE+      V 
Sbjct: 10628 KKPEVPPTK--------------VPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVA 10673

Query: 203   SDEPPG----PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEE------ 252
              +EPP       E   P Q  + P+   PE       +   +  P ++P++ +E      
Sbjct: 10674 LEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKK 10733

Query: 253   -------EPSSMQQEAPALPPESSMESLTLPNHEVSVQ-----PPGEDQAYYHLPNITVK 300
                    +P +   + P +P E       +P  +V+V      PP +       P +  K
Sbjct: 10734 VPLVVPKKPEAPPAKVPEVPKE------VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEK 10787

Query: 301   PA-DVEVTITSEPTNETESSQ--AQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSI 357
             PA  V     S P    E  +  A +E      E+  P A ++E  + PP  P E +  I
Sbjct: 10788 PAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKII 10847

Query: 358   SEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDV 417
              E++ PV      ++ E+ P ++  P +  E  ++   PP        A P   VK    
Sbjct: 10848 PEKKVPV-----IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP----APPKEDVKEKIF 10898

Query: 418   QLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQE 477
             QL    +        +  +   T L   G + +   ++   P   PE  EE    +V ++
Sbjct: 10899 QLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKK---VRKLLPERKPEPKEEVVLKSVLRK 10955

Query: 478   TSFQSPEPINNENPSPTQQEAAAE--HPQTAEEGE-SSLTHQE----APAQTPEFPNVVV 530
                +    +  +     ++ A  E   P+  EE E  ++T +E     P + PE    + 
Sbjct: 10956 RPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIP 11015

Query: 531   AQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
                PE     +A V+      TI P     VE  PT    P   P
Sbjct: 11016 LPAPEPKPKPEAEVK------TIKP---PPVEPEPTPIAAPVTVP 11051



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 106/504 (21%), Positives = 189/504 (37%), Gaps = 71/504 (14%)

Query: 114   DSAGEQPLEPEQFLASQQDL--KDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLS 171
             + A + P++P++ +A ++    + +++P  R+P  PK+L  +P +     E++    +  
Sbjct: 9865  EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL--EPEEVAFEEEVVTHVEEYL 9922

Query: 172   TPQSQKQTLQNEYSSTDTPYPGSLP------PELRVKSDEPPGPSEQVGPSQFHLEPET- 224
               + ++   + E   T+      +P      P   V  ++ P P  +   +     PE  
Sbjct: 9923  VEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVP 9982

Query: 225   QNPETLEDIQSSSLQQEAPAQLPQL----LEEE----PSSMQQEAP-ALPPESSMESLTL 275
             + PE    +     ++  PA++P++    + EE    P   + EAP A  PE  +    +
Sbjct: 9983  KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE--VPKKPV 10040

Query: 276   PNHEVSVQPPGEDQA----YYHLPNITV----KPADVEVTITSEPTNETESSQAQQETPI 327
             P  +V V  P + +A       +P   +    KP  V   + + P  +    +     P+
Sbjct: 10041 PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP-KVPKKREPVPVPV 10099

Query: 328   QFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP- 386
               P+E E    ++  P E  +P  E  L   E+  P +    P E E  P ++E P +  
Sbjct: 10100 ALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159

Query: 387   --PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
               PE  E                P   V P          P  E+   +  ++       
Sbjct: 10160 YVPEEEEFV--------------PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI---- 10201

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
                +  PPA      P +P+  EE   + + +E      E        P  +E   E P 
Sbjct: 10202 PKKEEAPPA----KVPEVPKKVEEK-RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP 10256

Query: 505   TAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
             + EE E     + AP + PE     V + P  + + +    P        PE K  V + 
Sbjct: 10257 SIEEVE-----EVAPPRVPEVIKKAVPEAP--TPVPKKVEAPPAKVSKKIPEEKVPVPVQ 10309

Query: 565   PTMKETP----TQPPKKVVPQLRV 584
                KE P     + PKK VP+ +V
Sbjct: 10310 --KKEAPPAKVPEVPKK-VPEKKV 10330



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 77/377 (20%), Positives = 135/377 (35%), Gaps = 61/377 (16%)

Query: 44    KDPLQLTSNPLGPPDSWSSHSSHF-PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
             K PL +   P  PP           P +    P  P  P       P+   E+P  P   
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP-------PAKVPEVPKKPVLE 10785

Query: 103   TENLVPFLDTWDSAG----EQPLE--PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQ 156
              +  VP  +  +S      E+P E  PE+ +A +++    ++ +E   V P  + ++P +
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845

Query: 157   RWSLAEIIGITRQLSTPQSQ---KQTLQNEYSSTDTPYPGSLPPELRVKS---------- 203
                  ++  I +  + P  +   ++ ++        P P   PP+  VK           
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905

Query: 204   ----DEP-------------PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
                 ++P             PG  ++V       +PE +    L+ +     ++E P   
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 10965

Query: 247   PQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEV 306
             P+ LE+       E P   P   +E  T+   E  +  P +      +P I  KPA    
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK------VPEI--KPAIPLP 11017

Query: 307   TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ--QPV 364
                 +P  E E    +       P  VEP  T   AP+  PV   + E    +++  +P 
Sbjct: 11018 APEPKPKPEAEVKTIK-------PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070

Query: 365   QPSESPREVESSPTQQE 381
              P +   +   SP + E
Sbjct: 11071 GPIKGVPKKTPSPIEAE 11087



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 104/539 (19%), Positives = 196/539 (36%), Gaps = 93/539 (17%)

Query: 176  QKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
            +++ +Q +    +  +   +P ++  K   PP P     P    +E  ++  E  E +Q 
Sbjct: 9146 EREVIQVQKEVYEESHERKVPAKVPEKKAPPP-PKVIKKPVIEKIEKTSRRMEE-EKVQV 9203

Query: 236  SSLQQEAPAQLPQLLEEEPSS---MQQEAPALPPES---SMESLTLPNH---EVSVQPPG 286
            + + + +   +PQ     P     ++ + PA+  +    S E +   +H   EVSV  P 
Sbjct: 9204 TKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPE 9263

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNET----ESSQAQQETPIQFPEEVEPSATQQEA 342
              +       +T +   V ++   EP  +     E    ++  P+  P++VEP A +   
Sbjct: 9264 VQKEI-----VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE 9318

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQE------------TPGQPPE-- 388
              + PVP  +  + +  +++P  P + P EV   P  +E             P + PE  
Sbjct: 9319 VPKKPVPEEKKPVPV-PKKEPAAPPKVP-EVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQ 9376

Query: 389  -----HHEVTV-------SPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA-EVGTSLVH 435
                   ++T+        PP   +      P      P  +  +   P    +    V 
Sbjct: 9377 KGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVP 9436

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPES---SEEAGPLAVQQETSFQSPEPINNENPS 492
            +E             PP  +     ++ E    +EE    AV Q       E    E  S
Sbjct: 9437 EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 9496

Query: 493  PTQQE-----AAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
             +++E     +     +  EE E+ +T  E   +  E+    V +   H    +   +P 
Sbjct: 9497 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEY----VVEEKLHIISKRVEAEPA 9552

Query: 548  DL------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
            ++         + P+   ++E  P  K    + PKK+VP+ +    V  P P +++   P
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAK--VPEAPKKIVPEKK----VPAPVPKKEKVPPP 9606

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
              P               EP   V    P K+  V PK  ++  P P +V  +H  +T+
Sbjct: 9607 KVPE--------------EPKKPV----PEKK--VPPKVIKMEEPLPAKVTERHMQITQ 9645



 Score = 31.2 bits (69), Expect = 9.0
 Identities = 92/481 (19%), Positives = 151/481 (31%), Gaps = 62/481 (12%)

Query: 328 QFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPP 387
           Q P +  P    +     P  P +  +  ++ QQ P     SP                 
Sbjct: 248 QLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSP----------------- 290

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
                    P  H      SP  SV P      I+  P   V + L+ ++       +G 
Sbjct: 291 --------SPVRHVRAPTPSPVRSVSP---AARISTSPIRSVRSPLLMRKTQASTVATGP 339

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
           +V PP  Q G       SS EA        TS Q       E     Q++        A 
Sbjct: 340 EVPPPWKQEG----YVASSSEAEMRETTLTTSTQIRTEERWEGRYGVQEQVTISGAAGAA 395

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITP--ESKTEVELSP 565
              S+     A A         V Q  + S      V  +D+     P   +  +     
Sbjct: 396 ASVSASASYAAEAVATGAKE--VKQDADKSAAVATVVAAVDMARVREPVISAVEQTAQRT 453

Query: 566 TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL---GLTITPEPT 622
           T      QP ++ V +      VT      D+A+     S T +++      + +T E  
Sbjct: 454 TTTAVHIQPAQEQVRKEAEKTAVTKVVVAADKAKEQELKSRTKEVITTKQEQMHVTHEQI 513

Query: 623 TEVGHST-PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
            +    T  PK  I + K  E      +++  +   +T+  ++  +   T     +    
Sbjct: 514 RKETEKTFVPKVVISAAKAKEQETRISEEITKKQKQVTQEAIRQ-ETEITAASMVVVATA 572

Query: 682 PSTALMTTAPPPGHPEVTLPPSDKGQAQHSHL---TQATVQPLDLELTITTK-------- 730
            ST L T    PG  E T    D+    +  +   T+ TV P  +  T   K        
Sbjct: 573 KSTKLETV---PGAQEETTTQQDQMHLSYEKIMKETRKTVVPKVIVATPKVKEQDLVSRG 629

Query: 731 ----PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTAL---EKTTAPRPDRVQTL 783
                T   +   T E+   +     L+ I   T + +    +    +T A R +++Q  
Sbjct: 630 REGITTKREQVQITQEKMRKEAEKTALSTIAVATAKAKEQETILRTRETMATRQEQIQVT 689

Query: 784 H 784
           H
Sbjct: 690 H 690


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 148/631 (23%), Positives = 212/631 (33%), Gaps = 102/631 (16%)

Query: 46  PLQLTSNPLGPPDSWSSH-SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
           P    + P+ PPD+ ++   +  P   P A  LP  P       P +   +P+PP     
Sbjct: 309 PSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPS--APPSLQTLPSPPATPPS 366

Query: 105 NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
              P + T        L   Q +   Q      SP  + P SP  L    A     +  +
Sbjct: 367 QAPPSMTTPPMQAPPSL---QTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 165 GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE---LRVKSDEPPGPSEQVGPSQFHLE 221
             T    T  S +QT   + S T    P S PP+   L+     P  P     P Q  L 
Sbjct: 424 QATHSFLT-MSPRQT---QASLTSPSRPASTPPDSPPLQAPLSLPASP-----PLQTSLS 474

Query: 222 PETQ---NPETLEDIQS-SSLQQEAP-AQLPQLLEEEPSSMQQEAPALPPESSMESLTLP 276
           P      +P T+  +Q+ SSL   +P A L  L+           P L  +SS+   +L 
Sbjct: 475 PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI----------MPPLETQSSLAPPSLQ 524

Query: 277 NHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQ-----QETPIQFPE 331
               S+  P  +    +LP++   P        + P  ET    A        +P+  P 
Sbjct: 525 TPPASLTTPPLE----NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPP 580

Query: 332 EVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQ--ETPGQP 386
              PS+     P  PP    PP++   S         P ++P  +   P Q     P  P
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 387 PEHHEVTVSP--PGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
           P     T SP  P     H L +P      P VQ   +   S  V  S     AT     
Sbjct: 641 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS-----ATPPSQA 695

Query: 445 SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
             +   PP      PP  P  S  A P         Q+P P+            AA   Q
Sbjct: 696 PPSLAAPPLQVPPSPPASPPMSPSATPPP-------QAPPPL------------AAPPLQ 736

Query: 505 TAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
                 +S     +    P  P ++ A P +                 + P     + +S
Sbjct: 737 VPPSPPASPPMSPSATPPPRVPPLLAAPPLQ-----------------VPPSPPASLPMS 779

Query: 565 PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGL------TIT 618
           P  K  P  PP    P L   Q + +P P     Q P SPS ++ +  L         + 
Sbjct: 780 PLAKPPPQAPPALATPPL---QALPSP-PASFPGQAPFSPSASLPMSPLATPPPQAPPVL 835

Query: 619 PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPD 649
             P  +V  S P   T+ +P+ P    P PD
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPT--PGPD 864



 Score = 61.2 bits (147), Expect = 8e-09
 Identities = 143/588 (24%), Positives = 203/588 (34%), Gaps = 100/588 (17%)

Query: 36  EAQPLEWVKDPLQLTSNPLGPPDSWSSHS--SHFPRESPHAPTLPADPWDFDHLGPSASS 93
           +A P       LQ T++ LG P   ++HS  +  PR++  + T P+ P         AS+
Sbjct: 401 QAPPSPLALSSLQATTS-LGSPTLQATHSFLTMSPRQTQASLTSPSRP---------AST 450

Query: 94  EMPAPPQESTENLV--PFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
              +PP ++  +L   P L T  S    PL     +   Q L    S   + P+S   L 
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS--SLI 508

Query: 152 KDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTP----YPGSLPPELRVKSDEPP 207
             P +  S          L+ P     +LQ   +S  TP     P   PP L+  S    
Sbjct: 509 MPPLETQS---------SLAPP-----SLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554

Query: 208 GPSEQVGPSQFHLE-PETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP 266
            P         HLE P    P  L         Q  P+ L     E PSS+    P  PP
Sbjct: 555 TP---------HLETPPCPAPCPL---------QAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 267 ESSMESLT-LPNHEVS--VQPPGEDQAYYHLPNITVKPAD-VEVTITSEPTNETESSQAQ 322
             +   L  LP+  +S    PP +      LP +   P+      ++   T   ++  A 
Sbjct: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656

Query: 323 QETPIQFPEEVEPSATQQ---EAPIEPPV-----PPMEHELSISE---QQQPVQPSESPR 371
               +Q P    PS   Q     P  PPV     PP +   S++    Q  P  P+  P 
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK----------PPDVQLTI 421
              ++P  Q  P       +V  SPP        A+P   V           PP    ++
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 422 AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQ 481
              P A+         AT  L    +   PPA   G  P  P +S    PLA       Q
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLATPPP---Q 830

Query: 482 SP----EPINNENPSP-------TQQEAAAEHPQTAEEGESSLTHQEAPAQTP---EFPN 527
           +P     P+    PSP         +      P T+  G   LT   AP   P     P+
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPGPPPPPSRSPS 889

Query: 528 VVVAQPPEHSHLTQATVQPLDL-GFTITPESKTEVELSPTMKETPTQP 574
             ++ P    H + AT  P +L G+   PE        P  +     P
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937



 Score = 58.2 bits (139), Expect = 7e-08
 Identities = 113/542 (20%), Positives = 173/542 (31%), Gaps = 109/542 (20%)

Query: 309 TSEPTNETESSQAQQETPIQFPEEVEPSATQQ------EAPIEPPVPPMEHELSISEQQQ 362
           T  P     S+ A+++T    P    P+  ++      E  +  P P            +
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP----------SAR 197

Query: 363 PVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIA 422
           P  P+E PR+  SS ++  T    P       +  G              +P    L+ +
Sbjct: 198 PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ------------RPASRSLSSS 245

Query: 423 AEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP-LAVQQETSFQ 481
           A P +    S      T R     +  +P  +Q   PP +    ++A P L     +   
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 305

Query: 482 SPEPINNE-NPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           +P P   +  P P    AA   P T             P  TP     +   PP  S   
Sbjct: 306 TPSPSGTKARPVPPPDNAATPLPATLPPSP--------PLATP-----LPLAPPSPS--- 349

Query: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKV--VPQLRVYQGVTNPTPGQDQA 598
                P  L    +P +    +  P+M   P Q P  +  +P ++V   +T+P+      
Sbjct: 350 ----APPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS-----L 400

Query: 599 QHPVSP-------------SVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEV-- 643
           Q P SP             S T+Q     LT++P  T +   ++P +     P  P +  
Sbjct: 401 QAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQT-QASLTSPSRPASTPPDSPPLQA 459

Query: 644 --TLPHPDQVQTQHSHLTRATVQPLDLGFTITP----KSMTEVEPSTALMTTAPPP---- 693
             +LP    +QT  S      V PL    TI P     S+    P   L +   PP    
Sbjct: 460 PLSLPASPPLQTSLS----PAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515

Query: 694 ---GHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT---------- 740
                P +  PP+        +L      PL       T P  E  P P           
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575

Query: 741 -------TEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGP 793
                  T  +   PP      +  P  +   S  L     P P     L  +L  +  P
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXL--ALPPLQAP 633

Query: 794 PT 795
           P+
Sbjct: 634 PS 635



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 147/696 (21%), Positives = 220/696 (31%), Gaps = 121/696 (17%)

Query: 138 SPQERLPVSPKKLKKDPAQ----RWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPG 193
           SP+   PV+P  L+   A     R  LAE  G     + P+S  +      + T +  P 
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91

Query: 194 SLPPELRVKSDEPP------GPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLP 247
           S PP        PP      GP    G +     P     + L      ++ +    + P
Sbjct: 92  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151

Query: 248 QLLEEEPSSMQQEAPALP--PESSME----------SLTLPNHEVSVQPPGEDQAYYHLP 295
           +       + +  +   P  P  +M            L  P      +PP E       P
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG------P 205

Query: 296 NITVKPADVEVTITSEPT------------NETESSQAQQETPIQFPEEVEPSAT-QQEA 342
             +V  A    T    P                  S +   TP+  P    PSA     A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 343 PIEPPVP-PMEHELSISEQQQPVQPSESPR--EVESSPTQQETPGQ------PPEHHEVT 393
           P  P  P P   +     Q  P +   +P    + SSP    +P        PP  +  T
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 394 VSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA 453
             P     +  LA+P + + PP         PSA      +     T  S +   +  P 
Sbjct: 326 PLPATLPPSPPLATP-LPLAPPS--------PSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 454 IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPI-------NNENPSPTQQEAAAEHPQTA 506
           +Q   PP L        P ++   +    P P+            SPT Q   +    + 
Sbjct: 377 MQ--APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 507 EEGESSLTHQEAPAQTP------EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            + ++SLT    PA TP      + P  + A PP  + L+ A V PL    TI P     
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQA-- 491

Query: 561 VELSPTMKETPTQPPKKVV-PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
             LS     +P  P   ++ P L     +  P+      Q P +   T  L +L  ++ P
Sbjct: 492 --LSSLASHSPQAPLSSLIMPPLETQSSLAPPS-----LQTPPASLTTPPLENLP-SLAP 543

Query: 620 EPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE 679
                     PP +T  +P    +T PH +               P        P  +T 
Sbjct: 544 ----------PPLQTASAP----LTTPHLETPPC-----------PAPCPLQAPPSPLTT 578

Query: 680 VEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
             P T      PPP  P     P  +G         AT  P          P   + P  
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP-------QAPPXLALPPLQ 631

Query: 740 TTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAP 775
                   PP   L+ +  P+ +  ++ A+    AP
Sbjct: 632 APPSPPASPP---LSPLATPSPQAPNALAVHLLQAP 664



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 111/481 (23%), Positives = 161/481 (33%), Gaps = 84/481 (17%)

Query: 358 SEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDV 417
           S +    +P  S R   + P +  +PG         VS PG       AS +    P   
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGP--------VSSPGR------ASGTTRPGPLGQ 131

Query: 418 Q-LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP-PLLPESSEEAGPLAVQ 475
           + L I+AE +   G +    + +   +G+  D   P    G P P +   S  AG     
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAG----- 184

Query: 476 QETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
             T    P P  +  P P  +         +   E S T     A+        + +P  
Sbjct: 185 --TEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239

Query: 536 HSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
            S  + AT  PL       P ++     +P     P+QP  K +  LR  Q VT P    
Sbjct: 240 RSLSSSAT--PLSSPARSGPSARG----TPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDA 292

Query: 596 DQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
             A  P+S S            TP P+       PP     +P  P    P P       
Sbjct: 293 APALGPLSSSPLA---------TPSPSGTKARPVPPPDNAATPL-PATLPPSP------- 335

Query: 656 SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
                    PL     + P S +   PS  L T   PP  P    PPS       +  + 
Sbjct: 336 ---------PLATPLPLAPPSPS-APPS--LQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383

Query: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHS--------T 767
            T+ P+ +  ++T+ P+ +  PSP    +      LG      PT +  HS        T
Sbjct: 384 QTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLG-----SPTLQATHSFLTMSPRQT 437

Query: 768 ALEKTTAPRPDRV----QTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEE 821
               T+  RP         L   L+    PP  T L PA   L    +    +AL++   
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 822 H 822
           H
Sbjct: 498 H 498


>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis
           critical region 1 [Homo sapiens]
          Length = 1400

 Score = 79.7 bits (195), Expect = 2e-14
 Identities = 151/713 (21%), Positives = 242/713 (33%), Gaps = 98/713 (13%)

Query: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           Q +  ST  P   +   +   K+   P  SE+   S+  +  +    +T ++IQ +    
Sbjct: 279 QTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISAN 338

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           E    L +  E    +  +     P E +       N   ++ P    +      N    
Sbjct: 339 ELTQSLAEPTEHGGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTA 398

Query: 301 PADVEVTITSEPTNETESSQAQQET--PIQFPEEVEPSATQQEAPIEPPVPPMEH-ELSI 357
           P        + PT   E +  +  T  P +  E  E +A +   P   P  P EH E + 
Sbjct: 399 P------FPAGPTENREMTANENTTLFPAEPTEHGERTANENTTP--SPAEPTEHGERTA 450

Query: 358 SEQQ--QPVQPSE--------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
           +E     P +P+E        + +   SS    E   + P  +E T   P     +   +
Sbjct: 451 NENTTPSPAEPTEHGERTPFANDKTTSSSAESTEHGERTPLANENTTPSPAEPTENRERT 510

Query: 408 PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
            + +  P     T   E +A   T+L   E T     + N+   P+      P  P  + 
Sbjct: 511 ANENTTPSPAGPTENRETTANEKTTLSPVEPTENRETTANEKTTPS------PAEPTENG 564

Query: 468 EAGPLAVQQETSFQSPE-------PINNENPSPTQQEAAAEHPQTAEEGE--SSLTHQEA 518
           +  P A ++ TS  +         P+ NEN +P+  E      +TA E    S     E 
Sbjct: 565 QRTPFANEKTTSSSAEPTEHGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTEN 624

Query: 519 PAQTP---EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
             +TP   E     +A+P E+   T    +      + + E     E +P   E  T  P
Sbjct: 625 GDRTPLANEKTTPSLAEPTENGQRTPFANEKTT---SSSAEPTEHEERTPLANENTTPSP 681

Query: 576 KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLL-DLGLTITPEPTTEVGHSTPPKRT 634
            +     R      N TP       P  P+   ++  +   T+ P   TE    T  ++T
Sbjct: 682 AEPTEN-RERTANENTTPS------PAGPTENREMTANEKTTLFPAEPTENRERTANEKT 734

Query: 635 IVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLG---------FTITPKSMTEVEPSTA 685
             SP  P     +  +    +   T ++ +P + G          T++P   TE    TA
Sbjct: 735 TSSPAEPT---ENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTLSPAGPTENRERTA 791

Query: 686 LMTTAPPPGHP---------EVTLP----PSDKGQAQ---HSHLTQATVQPLD--LELTI 727
              T P P  P         E T P    P++ G      +   T +  +P +       
Sbjct: 792 NEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEKTTPSLAEPTENGKRTPF 851

Query: 728 TTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTT----APRPDRVQTL 783
             + TT     PT     T   +      P   TE R  TA EKTT     P  +R  T 
Sbjct: 852 ANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTA 911

Query: 784 HRSLTEVTGPPTELEPAQDSLVQSESYTQNKALT----APEEHKASTSTNICE 832
           +   T     PTE          +  +T N+  T     P EH+  T   + E
Sbjct: 912 NEKTTPFPAEPTE----------NREWTANENTTLSPAEPTEHEEMTPLMVDE 954



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 190/978 (19%), Positives = 321/978 (32%), Gaps = 185/978 (18%)

Query: 50   TSNPLGPPDSWSSHSSHFPRESPHAPT-------------LPADPWDFDHLGPSASSEM- 95
            T +P  P ++    ++     SP  PT              PA P +   +  + ++ + 
Sbjct: 360  TPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREMTANENTTLF 419

Query: 96   PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQE---RLPVSPKKLKK 152
            PA P E  E       T   A  +P E  +  A++        P E   R P +  K   
Sbjct: 420  PAEPTEHGERTANENTTPSPA--EPTEHGERTANENTTPSPAEPTEHGERTPFANDKTTS 477

Query: 153  DPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTD--TPYPGSLPPELRVKSDEPPGPS 210
              A+     E   +  + +TP   + T   E ++ +  TP P   P E R  +       
Sbjct: 478  SSAESTEHGERTPLANENTTPSPAEPTENRERTANENTTPSPAG-PTENRETTANEKTTL 536

Query: 211  EQVGPSQFH----LEPETQNP-ETLEDIQSSSLQQE----APAQLPQLLEEEPSSMQQEA 261
              V P++       E  T +P E  E+ Q +    E    + A+  +  E  P + +   
Sbjct: 537  SPVEPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTT 596

Query: 262  PALPPESSMESLTLPNHEVSVQP--PGEDQAYYHLPNITVKPADVEVTITSEPT------ 313
            P+ P E +       N + +  P  P E+     L N    P+  E T   + T      
Sbjct: 597  PS-PAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPTENGQRTPFANEK 655

Query: 314  ---NETESSQAQQETPI----QFPEEVEPSATQQEAPIE-----PPVPPMEHELSISEQQ 361
               +  E ++ ++ TP+      P   EP+  ++    E     P  P    E++ +E+ 
Sbjct: 656  TTSSSAEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAGPTENREMTANEKT 715

Query: 362  Q--PVQPSESPREVESSPTQQETPGQPPEHHEVT-----------VSPPGHHQTHHLASP 408
               P +P+E+ RE  ++     +P +P E+ + T             P  H +   LA+ 
Sbjct: 716  TLFPAEPTEN-RERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANE 774

Query: 409  SVSVKPP-----------DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHG 457
            + ++ P            +      AEP+     +       +    + N    P     
Sbjct: 775  NTTLSPAGPTENRERTANEKTTPFPAEPTENRERTANENTTPSPAQPTENGDRTPLANEK 834

Query: 458  GPPLLPESSE--EAGPLAVQQETSFQSP-------EPINNENPSPTQQEAAAEHPQTAEE 508
              P L E +E  +  P A ++ TS  +         P+ NEN + +  E      +TA E
Sbjct: 835  TTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPAEPTENRERTANE 894

Query: 509  GESSL-------THQEAPAQTPEFP---------------NVVVAQPPEHSHLTQATV-- 544
              +             A  +T  FP                +  A+P EH  +T   V  
Sbjct: 895  KTTQFPAEPTENRESTANEKTTPFPAEPTENREWTANENTTLSPAEPTEHEEMTPLMVDE 954

Query: 545  -------------QPLDLGFTIT----PESKTEVEL--------SPTMKETPTQPPKKVV 579
                         +P D+  T+      ES T  E+        S T   T +    ++ 
Sbjct: 955  NLQAPFRQGSCAERPKDICATVASTTGSESSTASEIITSSTMSVSATASSTASSTASEIT 1014

Query: 580  -------------PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE-- 624
                           +R    V+ P      A        TV       T+T  PTT   
Sbjct: 1015 MSSAAIPVSSTAYETIRFSTAVSEPVTASILALESTLAFTTVSNTTTSSTVTSVPTTAST 1074

Query: 625  --VGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
                ++T  + T+       +T      V TQ S +   +V            + T  + 
Sbjct: 1075 SGSKNTTACEATMSETTIAAITASEDTTVSTQTSVIAAESVP--------HTATKTPTDT 1126

Query: 683  STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT--------- 733
            +TA ++   P  +    +  +       +  T  T        TIT+ PTT         
Sbjct: 1127 TTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTSKIT 1186

Query: 734  ---EVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEV 790
               E+  + TT+  +T           E    T   T  E TTA  P        + T  
Sbjct: 1187 AGSEIPTASTTDSATTAISTKASGTTVESAPSTAPPTPAETTTASVP--------TTTST 1238

Query: 791  TGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQ 850
            TG          S+  +   T +++ T  E  +ASTS    E+ T    M + +    E 
Sbjct: 1239 TGSENTGHHTVSSVPTTVFATASESSTGSETTRASTSAT--EVTTA---MTTAMTTGSET 1293

Query: 851  RLRQVPVPEPNTHNGTFT 868
             +     P   T +G  T
Sbjct: 1294 AVVSTKAPVTTTQSGFST 1311



 Score = 61.6 bits (148), Expect = 6e-09
 Identities = 157/780 (20%), Positives = 285/780 (36%), Gaps = 114/780 (14%)

Query: 79   ADPWDFDHLGPSASSEM---PAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD 135
            A+P + +   P A+      PA P E+ E       T   AG  P E  +  A+++    
Sbjct: 661  AEPTEHEERTPLANENTTPSPAEPTENRERTANENTTPSPAG--PTENREMTANEKTTLF 718

Query: 136  KLSPQE-RLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNE---YSSTDTPY 191
               P E R   + +K    PA+     +      + +T  S + T   E    ++ +T  
Sbjct: 719  PAEPTENRERTANEKTTSSPAEPTENGQRTPFANEKTTSSSAEPTEHGERTPLANENTTL 778

Query: 192  PGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
              + P E R ++      +E+  P  F  EP      T  +  + S     PAQ  +  +
Sbjct: 779  SPAGPTENRERT-----ANEKTTP--FPAEPTENRERTANENTTPS-----PAQPTENGD 826

Query: 252  EEPSSMQQEAPALP-PESSMESLTLPNHEVSVQPPGEDQAYYHLP----NITVKPADVEV 306
              P + ++  P+L  P  + +     N + +       +     P    N T  PA    
Sbjct: 827  RTPLANEKTTPSLAEPTENGKRTPFANEKTTSSSAEPTEHAERTPLANENTTSSPA---- 882

Query: 307  TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQP 366
                EPT   E +  ++ T  QFP   EP+  ++    E   P             P +P
Sbjct: 883  ----EPTENRERTANEKTT--QFP--AEPTENRESTANEKTTP------------FPAEP 922

Query: 367  SESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIA---- 422
            +E+ RE  ++     +P +P EH E+T      +        S + +P D+  T+A    
Sbjct: 923  TEN-REWTANENTTLSPAEPTEHEEMTPLMVDENLQAPFRQGSCAERPKDICATVASTTG 981

Query: 423  --AEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
              +  ++E+ TS     + T  S + +      +     P+   + E      ++  T+ 
Sbjct: 982  SESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYE-----TIRFSTAV 1036

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
              P   +      T       +  T+    S++T     A T    N    +    + ++
Sbjct: 1037 SEPVTASILALESTLAFTTVSNTTTS----STVTSVPTTASTSGSKNTTACE----ATMS 1088

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPP--------KKVVPQLRVYQGVTN-P 591
            + T+  +      T  ++T V  + ++  T T+ P           VP+      +T+ P
Sbjct: 1089 ETTIAAITASEDTTVSTQTSVIAAESVPHTATKTPTDTTTASVSATVPKNNTLSVITSTP 1148

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            +   + A   ++   T        TIT  PTT     T   +     + P  T    D  
Sbjct: 1149 STAPNTASKTMT---TASKTTTTSTITSLPTTVF---TTTSKITAGSEIP--TASTTDSA 1200

Query: 652  QTQHSHLTRATVQPLDLGFTITPKSMTEVE----PSTALMTTAPPPGHPEVTLPPSD--- 704
             T  S  T+A+   ++   +  P +  E      P+T   T +   GH  V+  P+    
Sbjct: 1201 TTAIS--TKASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFA 1258

Query: 705  --KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE---TSTQPPDLGLAIIPEP 759
                 +  S  T+A+    ++   +TT  TT  + +  + +   T+TQ       ++P  
Sbjct: 1259 TASESSTGSETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAK 1318

Query: 760  TTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
            TT     TA   TTA       TL+++  +         P  DS + S+S T +K ++ P
Sbjct: 1319 TT-----TASVSTTAS-----TTLYQNTIDSVAKSV---PTMDSTIASKSTTLSKIVSVP 1365



 Score = 42.4 bits (98), Expect = 0.004
 Identities = 97/430 (22%), Positives = 145/430 (33%), Gaps = 90/430 (20%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQ---TPEFPNVVVA 531
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +   TP   + +  
Sbjct: 171 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINC 230

Query: 532 QPPEHSHLT-----QATVQPLD-----LGFTITPESKTEVEL-----SPTMKETPTQPPK 576
           +       T       T +PL+     L  T T   KT         S T +++ + P K
Sbjct: 231 RKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTSFPEK 290

Query: 577 KVVPQLRVYQGVTNP-------------------TPGQDQAQHPVSPSVTVQLL------ 611
                   Y+    P                   T      Q  +S +   Q L      
Sbjct: 291 ITAASKTTYKTTGTPEESEKTEDSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEH 350

Query: 612 -----DLGLTITPEPTTEVGHSTPPKRTIVSPKHP---------EVTLPHP-----DQVQ 652
                +   T +P   TE    T  + T +SP  P         E T P P     ++  
Sbjct: 351 GGRTANENNTPSPAEPTENRERTANENTTLSPAEPTENRERTANENTAPFPAGPTENREM 410

Query: 653 TQHSHLTRATVQPLDLG-------FTITPKSMTEVEPSTALMTTAPPPGHP----EVTLP 701
           T + + T    +P + G        T +P   TE    TA   T P P  P    E T  
Sbjct: 411 TANENTTLFPAEPTEHGERTANENTTPSPAEPTEHGERTANENTTPSPAEPTEHGERTPF 470

Query: 702 PSDKGQAQHSHLTQ-ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPT 760
            +DK  +  +  T+     PL  E T T  P    +    T   +T P        P   
Sbjct: 471 ANDKTTSSSAESTEHGERTPLANENT-TPSPAEPTENRERTANENTTPS-------PAGP 522

Query: 761 TETRHSTALEKTT----APRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
           TE R +TA EKTT     P  +R  T +   T     PT  E  Q +   +E  T + A 
Sbjct: 523 TENRETTANEKTTLSPVEPTENRETTANEKTTPSPAEPT--ENGQRTPFANEKTTSSSA- 579

Query: 817 TAPEEHKAST 826
             P EH   T
Sbjct: 580 -EPTEHGERT 588


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 174/803 (21%), Positives = 280/803 (34%), Gaps = 117/803 (14%)

Query: 98   PPQESTENLVPFLDTWDSAGEQPL-------EPEQFLASQQDLKDKLSPQERLPVSPKKL 150
            P +  TE L+P   T D  GE+ L       E +Q LA  +D + + S +     SP++ 
Sbjct: 830  PLERETEKLLPERQT-DVTGEEELTKGKQDREQKQLLA--RDTQRQESDKNGESASPER- 885

Query: 151  KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPS 210
                  R SL   I  + ++   Q QKQTL ++    +   P +         +  P   
Sbjct: 886  -----DRESLKVEIETSEEIQEKQVQKQTLPSKAFEREVERPVA-------NRECDPAEL 933

Query: 211  EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSM 270
            E+  P    LE +TQ  E     +  S  Q+  A  P     EP     + P  P  + +
Sbjct: 934  EEKVPKVI-LERDTQRGEP----EGGSQDQKGQASSPT---PEPGVGAGDLPG-PTSAPV 984

Query: 271  ESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP 330
             S +      S   P   Q    L N  + PA+             ++S+ +    +   
Sbjct: 985  PSGSQSGGRGSPVSPRRHQK--GLLNCKMPPAE-------------KASRIRAAEKVSRG 1029

Query: 331  EEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPT--------QQET 382
            ++  P A       E P PP +   S S++     P  SP      PT         QE 
Sbjct: 1030 DQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEA 1089

Query: 383  PGQPPEHHEVTVSPPGHHQTHHLAS----PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEA 438
            P  P         P    +T   +     P+ S  P     T  A+P     TS   +  
Sbjct: 1090 PEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSR 1149

Query: 439  TTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEA 498
            T R S     V+ P              E   P A + + S  + +P+ +E   PT Q  
Sbjct: 1150 TNRSS-----VKTP--------------EPVVPTAPELQPSTSTDQPVTSE---PTSQVT 1187

Query: 499  AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPES- 557
                 +++ +   ++       Q    P+    +P      +QAT    +     TPE  
Sbjct: 1188 RGRKSRSSVKTPETVVPTALELQ----PSTSTDRPVTSEPTSQATRGRKNRSSVKTPEPV 1243

Query: 558  -KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV--QLLDLG 614
              T  EL P+   T T  P    P  +  +G  N +    +   PV P+           
Sbjct: 1244 VPTAPELQPS---TSTDQPVTSEPTYQATRGRKNRS--SVKTPEPVVPTAPELRPSTSTD 1298

Query: 615  LTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH--------LTRATVQPL 666
              +TP+PT+    +T  +  + S K PE  +P   ++Q   S          +R T    
Sbjct: 1299 RPVTPKPTSR---TTRSRTNMSSVKTPETVVPTAPELQISTSTDQPVTPKPTSRTTRSRT 1355

Query: 667  DLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELT 726
            ++     P+S   + P     T+   P  PE T   +   + + S  T  T+ P   +L 
Sbjct: 1356 NMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRKNRSSGKTPETLVPTAPKLE 1415

Query: 727  ITTKPTTEVKPSPTTEET-------STQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDR 779
             +T     V P PT++ T       S + P+  +   P    E + ST+ ++   P P  
Sbjct: 1416 PSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP----ELQPSTSTDQPVTPEPTS 1471

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDE 839
              T  R+       P  + P    L Q+ + T     + P         N   + T    
Sbjct: 1472 QATRGRTDRSSVKTPETVVPTAPEL-QASASTDQPVTSEPTSRTTRGRKNRSSVKTPETV 1530

Query: 840  MLSCIDLNPEQRLRQVPVPEPNT 862
            + +  +L P     Q   PEP +
Sbjct: 1531 VPAAPELQPSTSTDQPVTPEPTS 1553



 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 182/842 (21%), Positives = 292/842 (34%), Gaps = 127/842 (15%)

Query: 46   PLQLTSNPLGPPDSWSSHSS-HFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            P  +   P  P    +S S  H       +P LP+            S E P  P  S  
Sbjct: 1039 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSS-- 1096

Query: 105  NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
             L PF         +      F A+    +   S     PV+PK   +    R + + + 
Sbjct: 1097 ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV- 1155

Query: 165  GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRV----KSDEPPGPSEQVGPSQFHL 220
                   TP+    T      ST T  P +  P  +V    KS       E V P+   L
Sbjct: 1156 ------KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALEL 1209

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
            +P T    T   + S    Q    +  +   + P  +   AP L P +S +         
Sbjct: 1210 QPSTS---TDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 281  SVQPPGEDQAYYHLPNITVKPA-------DVEVTITSEPTNETESSQAQQETPIQFPEEV 333
                  ++++    P   V  A         +  +T +PT+ T  S+    + ++ PE V
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSS-VKTPETV 1325

Query: 334  EPSA------TQQEAPIEPP--------------VPPMEHELSISEQQQPVQPSESPREV 373
             P+A      T  + P+ P               V   E  + I+ +  P   +E P  V
Sbjct: 1326 VPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQP--V 1383

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
               PT + T G+  ++     +P     T     PS S   P     +  EP+++     
Sbjct: 1384 TPEPTSRATRGR--KNRSSGKTPETLVPTAPKLEPSTSTDQP-----VTPEPTSQ----- 1431

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEE--AGPLAVQQET-------SFQSPE 484
                AT   +   +   P  +    P L P +S +    P    Q T       S ++PE
Sbjct: 1432 ----ATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE 1487

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             +    P   Q  A+ + P T+E   S  T       + + P  VV   PE    T +T 
Sbjct: 1488 TVVPTAPE-LQASASTDQPVTSEP-TSRTTRGRKNRSSVKTPETVVPAAPELQPST-STD 1544

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP 604
            QP      +TPE  +      T + +  + P+ +VP     Q    P+  ++Q   P   
Sbjct: 1545 QP------VTPEPTSRATRGRTNRSS-VKTPESIVPIAPELQ----PSTSRNQLVTPEPT 1593

Query: 605  SVTVQLLDLGLTI-TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            S   +      ++ TPEP         P  +   P  P++T     +   + S  T   V
Sbjct: 1594 SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPV 1653

Query: 664  QPL--DLG-FT-----ITPKSMTEVEPSTALMTTA----PPPGHPEVTLPPSDKGQAQHS 711
            +P   DL  FT     +TP+++ +   S  L ++     P P  PE   P +        
Sbjct: 1654 EPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPE 1713

Query: 712  HLTQ--------ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL-----GLAIIPE 758
             +TQ        A   P  L   I  KP +     P ++ +  Q          L  IPE
Sbjct: 1714 PITQPSCIKRQRAAGNPGSLAAPIDHKPCS-APLEPKSQASRNQRWGAVRAAESLTAIPE 1772

Query: 759  PTT----ETR-HSTALEK---------TTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSL 804
            P +    ET  H++ ++K         T   +P   Q+  RSL  +  PP + +P +  +
Sbjct: 1773 PASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEV 1832

Query: 805  VQ 806
             Q
Sbjct: 1833 SQ 1834



 Score = 33.5 bits (75), Expect = 1.8
 Identities = 64/349 (18%), Positives = 130/349 (37%), Gaps = 44/349 (12%)

Query: 77   LPADPWDFDHLGPSASSEMPAPPQEST---------------ENLVPFLDTWD--SAGEQ 119
            +PA P     L PS S++ P  P+ ++               E++VP        ++  Q
Sbjct: 1531 VPAAP----ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQ 1586

Query: 120  PLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQT 179
             + PE    + +   ++ S +   PV P   +  P           +T + +  ++ + +
Sbjct: 1587 LVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSS 1646

Query: 180  LQN----EYSSTD----TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            ++     E +++D    TP   S+ PE   +     G S+ +  S     P    PE   
Sbjct: 1647 VKTPKPVEPAASDLEPFTPTDQSVTPEAIAQG----GQSKTLRSSTVRAMPVPTTPEFQS 1702

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTL-PNHEVSV-QPPGEDQ 289
             + +       P   P  ++ + ++    + A P +    S  L P  + S  Q  G  +
Sbjct: 1703 PVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVR 1762

Query: 290  AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVP 349
            A     ++T  P      +   P + ++  + +     +F  E++P A+Q        + 
Sbjct: 1763 A---AESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMD 1819

Query: 350  PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPG 398
               H      Q+QP +   S + V     +++T  +P +  +V    PG
Sbjct: 1820 SPPH------QKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPG 1862


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 157/680 (23%), Positives = 233/680 (34%), Gaps = 121/680 (17%)

Query: 170 LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPP-GPSEQVGPSQFHLEPETQNPE 228
           LS  + Q+   Q  +   D P PG +P EL    + PP  P   + PSQ ++ P      
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGP-PGLVPMELESPPESPPVPPGSYMPPSQSYMPPP----- 168

Query: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
                      Q  P+  P      P+S Q   P LPP     S + P+       P   
Sbjct: 169 -----------QPPPSYYP------PTSSQ---PYLPPAQPSPSQSPPSQSYLAPTPSYS 208

Query: 289 QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +           +    +  S   +   SSQA    P Q       S +Q  AP  P  
Sbjct: 209 SS-----------SSSSQSYLSHSQSYLPSSQASPSRPSQ-----GHSKSQLLAPPPPSA 252

Query: 349 PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHL 405
           PP       + QQ+P+   ES  + +S+  QQ  P   P     T++P    Q     HL
Sbjct: 253 PPGN---KTTVQQEPL---ESGAKNKSTEQQQAAPEPDPS----TMTPQEQQQYWYRQHL 302

Query: 406 ASPSVSVK---PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
            S     K   P   +  + A+ + E     V   AT+++  S +  EPP         L
Sbjct: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP---------L 353

Query: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
           P  +EE  P    +E   + PE    E+    Q +AAA H Q  ++      +Q    + 
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPE----EDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409

Query: 523 PEFPNVV-----VAQPPEHSHLTQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQ 573
            +   ++     + QPP H       +Q                + E E     ++  + 
Sbjct: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469

Query: 574 PPKKVVP----QLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
           P K  +     Q + +QG    T  Q   Q  V+    ++   +G    P P        
Sbjct: 470 PHKDQLQEYEKQWKTWQGHMKAT--QSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMP 527

Query: 630 PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT 689
           PP  T+  P  P  +LP P              V P  L  T+ P  M       +L T+
Sbjct: 528 PPLPTMPPPVLPP-SLPPP--------------VMPPALPATVPPPGMPPPVMPPSLPTS 572

Query: 690 APPP---------GHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
            PPP         G P V  PPS         L   ++        +   P +   P P 
Sbjct: 573 VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 741 TEETSTQ---PPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTEL 797
                     PP L  A +P P + ++ S   EK   PRP  + T    ++  + PPT  
Sbjct: 633 IPPPGVPQGIPPQLTAAPVP-PASSSQSSQVPEK---PRPALLPT---PVSFGSAPPTTY 685

Query: 798 EPAQDSLVQSESYTQNKALT 817
            P   S   SE       L+
Sbjct: 686 HPPLQSAGPSEQVNSKAPLS 705



 Score = 40.4 bits (93), Expect = 0.015
 Identities = 124/590 (21%), Positives = 198/590 (33%), Gaps = 91/590 (15%)

Query: 46  PLQLTSNPLGPPDSWSSH----SSHFPRESP---HAPTLPADPWDFDHLGPSASSEMPAP 98
           P++L S P  PP    S+     S+ P   P   + P   + P+    L P+  S   +P
Sbjct: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPY----LPPAQPSPSQSP 195

Query: 99  PQESTENLVPFLDTWDSAGEQPLEPEQ-FLASQQDLKDKLSPQERLPVSPKKLKKDPAQR 157
           P +S     P   +  S+ +  L   Q +L S Q              SP +    P+Q 
Sbjct: 196 PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQ-------------ASPSR----PSQG 238

Query: 158 WSLAEIIGITRQLSTPQSQKQTLQNE-------------YSSTDTPYPGSLPPELRVKSD 204
            S ++++      S P   K T+Q E               +   P P ++ P+ + +  
Sbjct: 239 HSKSQLLAPPPP-SAPPGNKTTVQQEPLESGAKNKSTEQQQAAPEPDPSTMTPQEQQQYW 297

Query: 205 EPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPAL 264
                      ++ HL    + P   +D     +++E        + E PSS   E P L
Sbjct: 298 YRQHLLSLQQRTKVHLPGHKKGPVVAKDTPEP-VKEEVTVPATSQVPESPSS---EEPPL 353

Query: 265 PPESSMESLTLPNHEVSVQPPGED-------QAYYHLPNITVKPADVEVTITSEPTNETE 317
           PP +      LP  E   + P ED        A  H           +     +   + +
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQ 413

Query: 318 SSQAQQETPIQFPEEVEPSAT--------QQEAPIEPPVPPMEHELSISEQQQPVQP-SE 368
               Q +  IQ P  ++  +          Q+   +      E E  + E+Q    P  +
Sbjct: 414 QILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKD 473

Query: 369 SPREVESS-PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
             +E E    T Q        + +  V+   + +  ++   ++S+ PP V  +    P  
Sbjct: 474 QLQEYEKQWKTWQGHMKATQSYLQEKVNSFQNMKNQYMG--NMSMPPPFVPYSQMPPPLP 531

Query: 428 EVGTSLVHQE-----------ATTRLSGSGNDVEPPAIQHG-GPPLLPESSEEAGPLAVQ 475
            +   ++              AT    G    V PP++     PP +P S   AGP  V 
Sbjct: 532 TMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVL 591

Query: 476 QETSFQS--PEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQP 533
              S  S  P P+      P    + A  P       SS T    P   P  P V    P
Sbjct: 592 PPPSLSSAGPPPV----LPPPSLSSTAPPPVMPLPPLSSAT--PPPGIPP--PGVPQGIP 643

Query: 534 PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR 583
           P+   LT A V P     +     K    L PT     + PP    P L+
Sbjct: 644 PQ---LTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQ 690


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 160/669 (23%), Positives = 217/669 (32%), Gaps = 114/669 (17%)

Query: 36   EAQPLEWVKDPLQLTSNPLGPPDSWSS--HSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
            E  P+E   DP      P+   D   S  HS    R      TL            S   
Sbjct: 541  ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLR-----------SGRK 589

Query: 94   EMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVSPKKL 150
            + PA P   T    P  +   S+G     P     S  D K    K S ++    +   L
Sbjct: 590  KQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEASSPL 644

Query: 151  KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDEPPGP 209
            K +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE    
Sbjct: 645  KSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 700

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
             + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P  SS
Sbjct: 701  PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTPAPSS 753

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
                          PPG  Q    LP     P+   V     PT    +SQA  +   Q 
Sbjct: 754  A-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP--QA 790

Query: 330  PEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPE 388
            P    P    Q+AP + P  PP  H         P+QP        S+P+      QPP 
Sbjct: 791  PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----AQPPL 846

Query: 389  HHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQEATT 440
            H +    PPG H         H   P     PP      A++  A +GTS    +   + 
Sbjct: 847  HGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYPHTSL 898

Query: 441  RLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPIN 487
            +L  S + ++             P A+ H  PP      +   P A +       P P +
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 488  ---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQPPEH 536
               N  P P  +     +  HP +A      L  Q      +PAQ P         PP  
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA 1018

Query: 537  SH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPT 592
            SH    L Q   QP        P     +   PT   T T P            G     
Sbjct: 1019 SHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAA--A 1075

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-HPDQV 651
             G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H  Q 
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSHASQS 1130

Query: 652  QTQHSHLTR 660
               + HL R
Sbjct: 1131 ARFYKHLDR 1139



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 145/670 (21%), Positives = 223/670 (33%), Gaps = 123/670 (18%)

Query: 118  EQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGITRQLSTPQSQ 176
            E+P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 128/599 (21%), Positives = 196/599 (32%), Gaps = 115/599 (19%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE----- 770
            +L        + +P  E  + P+P        PP   +  +P P    +H   L      
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH-KHPPHLSGPSPF 957

Query: 771  --KTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                  P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 958  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 160/669 (23%), Positives = 217/669 (32%), Gaps = 114/669 (17%)

Query: 36   EAQPLEWVKDPLQLTSNPLGPPDSWSS--HSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
            E  P+E   DP      P+   D   S  HS    R      TL            S   
Sbjct: 541  ELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLR-----------SGRK 589

Query: 94   EMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVSPKKL 150
            + PA P   T    P  +   S+G     P     S  D K    K S ++    +   L
Sbjct: 590  KQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEASSPL 644

Query: 151  KKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDEPPGP 209
            K +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE    
Sbjct: 645  KSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSD 700

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
             + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P  SS
Sbjct: 701  PKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTPAPSS 753

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
                          PPG  Q    LP     P+   V     PT    +SQA  +   Q 
Sbjct: 754  A-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP--QA 790

Query: 330  PEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPE 388
            P    P    Q+AP + P  PP  H         P+QP        S+P+      QPP 
Sbjct: 791  PTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----AQPPL 846

Query: 389  HHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQEATT 440
            H +    PPG H         H   P     PP      A++  A +GTS    +   + 
Sbjct: 847  HGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYPHTSL 898

Query: 441  RLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPIN 487
            +L  S + ++             P A+ H  PP      +   P A +       P P +
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 488  ---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQPPEH 536
               N  P P  +     +  HP +A      L  Q      +PAQ P         PP  
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPA 1018

Query: 537  SH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPT 592
            SH    L Q   QP        P     +   PT   T T P            G     
Sbjct: 1019 SHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAA--A 1075

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-HPDQV 651
             G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H  Q 
Sbjct: 1076 SGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSHASQS 1130

Query: 652  QTQHSHLTR 660
               + HL R
Sbjct: 1131 ARFYKHLDR 1139



 Score = 66.2 bits (160), Expect = 3e-10
 Identities = 145/670 (21%), Positives = 223/670 (33%), Gaps = 123/670 (18%)

Query: 118  EQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGITRQLSTPQSQ 176
            E+P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 32.3 bits (72), Expect = 4.0
 Identities = 128/599 (21%), Positives = 196/599 (32%), Gaps = 115/599 (19%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALE----- 770
            +L        + +P  E  + P+P        PP   +  +P P    +H   L      
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH-KHPPHLSGPSPF 957

Query: 771  --KTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                  P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 958  SMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 147/613 (23%), Positives = 202/613 (32%), Gaps = 101/613 (16%)

Query: 90  SASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKD---KLSPQERLPVS 146
           S   + PA P   T    P  +   S+G     P     S  D K    K S ++    +
Sbjct: 32  SGRKKQPASPDGRTS---PINEDIRSSGRN--SPSAASTSSNDSKAETVKKSAKKVKEEA 86

Query: 147 PKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS-LPPELRVKSDE 205
              LK +  QR    E +    + +   S K+T   E S  ++P  G     + R  +DE
Sbjct: 87  SSPLKSNKRQR----EKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDE 142

Query: 206 PPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALP 265
                + +        P   +P+  E    SS QQ       Q+L+ +P ++Q      P
Sbjct: 143 GSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQ-------QMLQAQPPALQAPTGVTP 195

Query: 266 PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
             SS              PPG  Q    LP     P+   V     PT    +SQA  + 
Sbjct: 196 APSSA-------------PPGTPQ----LPTPGPTPSATAVPPQGSPT----ASQAPNQP 234

Query: 326 PIQFPEEVEPSATQQEAP-IEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
             Q P    P    Q+AP + P  PP  H         P+QP        S+P+      
Sbjct: 235 --QAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSH----A 288

Query: 385 QPPEHHEVTVSPPGHHQ------THHLASPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQ 436
           QPP H +    PPG H         H   P     PP      A++  A +GTS    + 
Sbjct: 289 QPPLHGQ---GPPGPHSLQAGPLLQHPGPPQPFGLPPQ-----ASQGQAPLGTSPAAAYP 340

Query: 437 EATTRLSGSGNDVE-------------PPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             + +L  S + ++             P A+ H  PP      +   P A +       P
Sbjct: 341 HTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGP 400

Query: 484 EPIN---NENPSPTQQ---EAAAEHPQTAEEGESSLTHQ-----EAPAQTPEFPNVVVAQ 532
            P +   N  P P  +     +  HP +A      L  Q      +PAQ P         
Sbjct: 401 SPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLP 460

Query: 533 PPEHSH----LTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGV 588
           PP  SH    L Q   QP        P     +   PT   T T P            G 
Sbjct: 461 PPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGA 519

Query: 589 TNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-H 647
                G   A     P  TVQ+ +  L    EP      S PP     SP+   V  P H
Sbjct: 520 A--ASGGSIAGGSSCPLPTVQIKEEALDDAEEP-----ESPPPPPRSPSPEPTVVDTPSH 572

Query: 648 PDQVQTQHSHLTR 660
             Q    + HL R
Sbjct: 573 ASQSARFYKHLDR 585



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 133/624 (21%), Positives = 202/624 (32%), Gaps = 113/624 (18%)

Query: 180 LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
           L  ++S       GS+      +  +P  P  +  P    +    +N  +     S+  +
Sbjct: 12  LSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK 71

Query: 240 QEAPAQLPQLLEEEPSS------MQQEAPALPPESS---------MESLTLPNH------ 278
            E   +  + ++EE SS       Q+E  A   E +          + ++ PN       
Sbjct: 72  AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG 131

Query: 279 EVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF--PEEVEPS 336
           E S      D+      +I         +I S   NE++S  + Q+  +Q   P    P+
Sbjct: 132 ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 191

Query: 337 ATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP 396
                    PP  P       +     V P  SP     +P Q + P  P  H  +  +P
Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 397 PGHHQ---THHLASPSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND---- 448
             H Q   + H   P  S  PP   LT  A +PSA          A   L G G      
Sbjct: 251 ALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHS 302

Query: 449 -VEPPAIQHGGPP----LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEA 498
               P +QH GPP    L P++S+   PL     A    TS Q P        +   Q+ 
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQP 358

Query: 499 AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPES 557
             E P        ++ H + P  TP  P +   Q  +H  HL+  +   ++      P  
Sbjct: 359 PREQP--LPPAPLAMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 415

Query: 558 KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTI 617
           K    LS     +   PP +++PQ +         PG  Q+Q+                +
Sbjct: 416 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------L 459

Query: 618 TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSM 677
            P P      S PP                        + L +   QP        P   
Sbjct: 460 PPPPA-----SHPP------------------------TGLHQVAPQPPFAQHPFVPGGP 490

Query: 678 TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
             + P T   T+ PP G      PP     A    +   +  PL         PT ++K 
Sbjct: 491 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKE 541

Query: 738 SPTTE-ETSTQPPDLGLAIIPEPT 760
               + E    PP    +  PEPT
Sbjct: 542 EALDDAEEPESPPPPPRSPSPEPT 565



 Score = 54.7 bits (130), Expect = 8e-07
 Identities = 107/499 (21%), Positives = 158/499 (31%), Gaps = 82/499 (16%)

Query: 79  ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLS 138
           +DP D D    S S  +P+P    +++        DS+ +Q +   Q  A Q       +
Sbjct: 145 SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 196

Query: 139 PQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
           P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 255

Query: 199 LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                  PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 314

Query: 246 LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
            PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 315 -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373

Query: 297 ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
           I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 374 IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 419

Query: 357 ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                 P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 420 SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 470

Query: 417 VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
           +       P A                      + P +  G PP+ P +           
Sbjct: 471 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 508

Query: 477 ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
            TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 509 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 568

Query: 533 PPEHSHLTQATVQPLDLGF 551
            P H+  +    + LD G+
Sbjct: 569 TPSHASQSARFYKHLDRGY 587



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
           +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 82  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 141

Query: 365 QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
           + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 194

Query: 425 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
           P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 485 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 251 ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 295

Query: 545 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                     P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 296 ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 346

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 399

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 400 PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 450

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780
             L  +    P     P     + + QPP      +P                 P P   
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 495

Query: 781 QTLHRSLTEVTGPPTELEP 799
            T   + T   GP T  +P
Sbjct: 496 PTCPSTSTPPAGPGTSAQP 514



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 87/351 (24%), Positives = 119/351 (33%), Gaps = 64/351 (18%)

Query: 46  PLQLTSNPLGPPDSWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
           PLQ  +   G P + S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 326

Query: 105 NLVPFLDTWDSAGEQPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
              P L T   A   P    Q  ASQ  L+ +  P+E+ P+ P  L     +      I 
Sbjct: 327 GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQ-PLPPAPLAMPHIKPPPTTPI- 382

Query: 165 GITRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
               QL  PQ+ K                  PP L              GPS F +    
Sbjct: 383 ---PQLPAPQAHKH-----------------PPHLS-------------GPSPFSMNANL 409

Query: 225 QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN------- 277
             P  L+ + S S      A  P L     S     +PA PP    +S  LP        
Sbjct: 410 PPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPASHPP 468

Query: 278 ---HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP-EEV 333
              H+V+ QPP     +   P +   P      IT      T +  A   T  Q P    
Sbjct: 469 TGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPPCSGA 519

Query: 334 EPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
             S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 520 AASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 142/628 (22%), Positives = 217/628 (34%), Gaps = 87/628 (13%)

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
            D Q++ L+ +APA   +     P  + Q+     PES + SL L   E+ + P G +   
Sbjct: 725  DYQATLLEDQAPAHFHRNF---PEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVE--- 778

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  TV     E+ + S    E E   +     I FPE+    A   E  +E  +P +
Sbjct: 779  ------TVNDTKPELNVASSEGGEMERRDSDSFLNI-FPEKQVTKAGNTEPVLEEWIPVL 831

Query: 352  EHEL------SISEQQQPVQPS-ESPREVESSPTQQETPG----QPPEHHEVTVSPPGHH 400
            +         ++ +      PS E    + + P  + T       P  H ++ V+     
Sbjct: 832  QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSL 891

Query: 401  QTHHLAS-----------PSVSVKPPDVQLTIAA----EPSAEVGTSLVHQEATTRLSGS 445
            +   + +           P+V+V  P+    +AA    E +A    + + QE  + ++G 
Sbjct: 892  EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951

Query: 446  GNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHPQ 504
              +    AI     P+  E     GP  V   T+  +P EP        T +E A+  P 
Sbjct: 952  SPEWAALAIT---VPITEEDGTPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPAS--PA 1004

Query: 505  TAEEGESSLTHQEAPAQTPEFP-NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
             A       T   A   TPE P +   A PP     + A   P       TPE  T    
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-------TPEEPTSPAA 1057

Query: 564  SPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPT 622
            +    E PT P   V  P+         PTP     + P SP+  V         TPE  
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVP--------TPEEP 1104

Query: 623  TEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
            T    + P   T   P  P   +P P++  +       A   P +  F        E   
Sbjct: 1105 TSPAAAVP---TPEEPASPAAAVPTPEEPASP----AAAVPTPEEPAFPAPAVPTPEESA 1157

Query: 683  STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK----PTTEVKPS 738
            S A+    P          P+    A  + +     +P     ++ T      T E   S
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217

Query: 739  PTTE-ETSTQPPDLGLAII--PEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
            P     TS +P  L  A+    EPT+       LE+ T+     V T     +     PT
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA-AVLTPEELSSPAASVPT 1276

Query: 796  ELEPAQDSLVQS---ESYTQNKALTAPE 820
              EPA  +   S   E  +   A+  PE
Sbjct: 1277 PEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 90/376 (23%), Positives = 129/376 (34%), Gaps = 51/376 (13%)

Query: 169  QLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
            ++STP+          ++  TP   + P       +EP  P+  V P +    P    P 
Sbjct: 993  RVSTPEEPASPA----AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP- 1047

Query: 229  TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
            T E+  S +     P        EEP+S     P  P E +  +  +P  E    P    
Sbjct: 1048 TPEEPTSPAAAVPTP--------EEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPA--- 1095

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
             A    P     PA       + PT E  +S A     +  PEE    A     P EP  
Sbjct: 1096 -AAVPTPEEPTSPA------AAVPTPEEPASPA---AAVPTPEEPASPAAAVPTPEEPAF 1145

Query: 349  P----PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
            P    P   E + +    P  P ES     + PT  E+          T+  P       
Sbjct: 1146 PAPAVPTPEESASAAVAVPT-PEESASPAAAVPTPAESASFAAV--VATLEEP------- 1195

Query: 405  LASPSVSVKPPDVQLTIAAE---PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPL 461
              SP+ SV  P   +    E   P+A V TS   +E  +  +   N  EP +     P L
Sbjct: 1196 -TSPAASVPTPAAMVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTL 1251

Query: 462  LPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPA- 520
               +S  A  L  ++ +S  +  P   E  SP    +  E P +      +      PA 
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311

Query: 521  --QTPEFPNVVVAQPP 534
               TPE P +  A  P
Sbjct: 1312 SVPTPEVPAIPAAAVP 1327


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 122/507 (24%), Positives = 181/507 (35%), Gaps = 72/507 (14%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAA 423
              PSE P      PT    P + P       + P    T     P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESKTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE  T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHST--------PPKRTIVSPKHPEVTLP------ 646
               PS+ ++   L    T E TT V  +T        P ++  +S + P  T+P      
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKP--TIPTEKPTI 866

Query: 647  HPDQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEV 698
             P+++      LT  T +P        +       P     + P    ++T  P    E 
Sbjct: 867  SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 699  TLPPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAI 755
               P+++       LT  T +P     +LTI T KPT   +      E  T P +     
Sbjct: 927  PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIP 986

Query: 756  IPEPTTETRHSTALEKTTAPRPDRVQT 782
              +PT  T   TAL     P P    T
Sbjct: 987  TEKPTIPTEKLTALR---PPHPSPTAT 1010



 Score = 71.6 bits (174), Expect = 6e-12
 Identities = 126/557 (22%), Positives = 203/557 (36%), Gaps = 89/557 (15%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSSTDTPYPGS 194
            +K S     P  PK+    P ++ +      I+ +  T  S+K  + +E  +  +  P  
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPT------ISTEKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
            PS      P   P  SME   +   + ++ P          P I           T +PT
Sbjct: 689  PS-----IPTEKPTISMEETIISTEKPTISP--------EKPTIP----------TEKPT 725

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
              TE S    E P    E  +P+   ++  I P  P    E      ++   P+E P   
Sbjct: 726  IPTEKSTISPEKPTTPTE--KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP--- 780

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
             + PT  E P  P E   ++   P    T      ++S + P + +     P+ E  TS+
Sbjct: 781  -TIPT--EKPTIPTEKPTISTEEP----TTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
              +E T         +E P I    P +      E   ++ ++ T       I  E P+ 
Sbjct: 834  --EETTISTEKLTIPMEKPTISTEKPTI----PTEKPTISPEKLTIPTEKLTIPTEKPTI 887

Query: 494  TQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF-- 551
              +E      +     E      E P  + E P +   +P   +  T  + + L +    
Sbjct: 888  PIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEK 947

Query: 552  -TITPESKTEVELSPTMK-ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQ 609
             TI+PE  T     PT+  E PT P +K          +T PT      + P  P     
Sbjct: 948  PTISPEKLTIPTEKPTISTEKPTIPTEK----------LTIPT------EKPTIP----- 986

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH-PDQVQTQHSHLTRATVQPLDL 668
                    T +PT         K T + P HP  T       V + H+  T  T   + L
Sbjct: 987  --------TEKPTIPT-----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMT--SVIL 1031

Query: 669  GFTITPKSMTEVEPSTA 685
            G T T +S TE  P  A
Sbjct: 1032 GTTTTSRSSTERCPPNA 1048



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 96/423 (22%), Positives = 164/423 (38%), Gaps = 55/423 (13%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPD--SWSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P +  +  S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQESTENLV--PFLDTWDSA--GEQPLEP--------EQFLA 128
                   P+  +E P  P E T   +  P + T   +   E+P  P        E+ + 
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 129 SQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGITRQLSTPQSQKQTLQNEYSST 187
           S +  K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T
Sbjct: 706 STE--KPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTT 761

Query: 188 DTPYPGSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEA 242
            T  P   P +L + +++P  P+E+       P+    EP T   ET    +  S+  E 
Sbjct: 762 PTEKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEK 821

Query: 243 PAQLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHL 294
           P  LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++     
Sbjct: 822 PT-LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPT 875

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHE 354
             +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E E
Sbjct: 876 EKLTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE-E 933

Query: 355 LSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKP 414
            +IS ++  + P+E P     SP +   P + P       + P    T     P++  + 
Sbjct: 934 TTISTEKLTI-PTEKP---TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEK 989

Query: 415 PDV 417
           P +
Sbjct: 990 PTI 992



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 111/525 (21%), Positives = 180/525 (34%), Gaps = 91/525 (17%)

Query: 68   PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQPLEPEQFL 127
            P  +   PT+P +        P+ S+E P  P E            +   E+P  P +  
Sbjct: 577  PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEKP----------NMPSEKPTIPSE-- 624

Query: 128  ASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQNEYSST 187
                               P  L + P           I  +  T  S+K T+  E  + 
Sbjct: 625  ------------------KPTILTEKPT----------IPSEKPTIPSEKPTISTEKPTV 656

Query: 188  DTPYPGSLPPELRVKSDEPPGPSEQVG-PSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
             T  P +   E     +EP  P+E+   P++    P  +   ++E+   S+ +     + 
Sbjct: 657  PTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPEK 716

Query: 247  PQLLEEEPSSMQQEAPALP--PESSMESLTLPNHEVSVQP-----PGEDQAYYHLPNITV 299
            P +  E+P+   +++   P  P +  E  T+P  + ++ P     P E       P    
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTI--SPEKLT 774

Query: 300  KPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISE 359
             P +     T +PT  TE      E P    EE   S  +   P+E P  P E E + S 
Sbjct: 775  IPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTE-ETTTSV 833

Query: 360  QQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL 419
            ++  +   +    +E      E P  P E  + T+SP        L  P+  +  P  + 
Sbjct: 834  EETTISTEKLTIPMEKPTISTEKPTIPTE--KPTISP------EKLTIPTEKLTIPTEKP 885

Query: 420  TIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP------PLLP--ESSEEAGP 471
            TI  E      T++  ++ T          E P I    P      P +P  E++     
Sbjct: 886  TIPIEE-----TTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEK 940

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA-PAQTPEFP--NV 528
            L +  E    SPE +      PT    + E P    E  +  T +   P + P  P   +
Sbjct: 941  LTIPTEKPTISPEKLTIPTEKPT---ISTEKPTIPTEKLTIPTEKPTIPTEKPTIPTEKL 997

Query: 529  VVAQPPEHS-------------HLTQATVQPLDLGFTITPESKTE 560
               +PP  S             H     +  + LG T T  S TE
Sbjct: 998  TALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 92/394 (23%), Positives = 146/394 (37%), Gaps = 72/394 (18%)

Query: 64   SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP-LE 122
            S+  P  SP  PT+P +         + S E P  P E      P + T     E+P + 
Sbjct: 706  STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-----PTIPT-----EKPTIS 755

Query: 123  PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTLQN 182
            PE+            +P E+  +SP+KL               I  +  T  ++K T+  
Sbjct: 756  PEK----------PTTPTEKPTISPEKLT--------------IPTEKPTIPTEKPTIPT 791

Query: 183  EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQE- 241
            E  +  T  P +   E  + +++P  P E         +P     ET   ++ +++  E 
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK 842

Query: 242  --APAQLPQLLEEEPSSMQQEAPALPPES---SMESLTLPNHEVSVQPPGEDQAYYHLPN 296
               P + P +  E+P ++  E P + PE      E LT+P  + ++       +   L  
Sbjct: 843  LTIPMEKPTISTEKP-TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 297  ITVKPADVEVTITSE-PTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP-------- 347
             T KP     TI+ E PT  TE      E P    EE   S  +   P E P        
Sbjct: 902  PTEKP-----TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +P  +  +S  +   P +    P E  + PT  E P  P E       P        LA+
Sbjct: 957  IPTEKPTISTEKPTIPTEKLTIPTEKPTIPT--EKPTIPTEKLTALRPPHPSPTATGLAA 1014

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
              +S   P   +T     S  +GT+   + +T R
Sbjct: 1015 LVMSPHAPSTPMT-----SVILGTTTTSRSSTER 1043



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESKTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHST-PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRVQTLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 32.0 bits (71), Expect = 5.3
 Identities = 73/340 (21%), Positives = 117/340 (34%), Gaps = 46/340 (13%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F     S T  V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSP 638
           +P+L     V++  P +      ++ + T+      ++I     T    + P ++  +  
Sbjct: 539 LPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595

Query: 639 KHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST------ALMTTAPP 692
           + P ++   P     + +  +     P +    +T K     E  T       + T  P 
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPT 655

Query: 693 PGHPEVTLP-------------PSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEVK 736
               E T P             P++K        +  T +P + +E TI  T KPT   +
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 737 PSPTTEETSTQPPDLGLAIIPEPTTETRHST--------ALEKTTAPRPDRVQTLHRSLT 788
                 E  T P +       +PTT T   T        + EK T P  ++       LT
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLT 774

Query: 789 EVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
             T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 775 IPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.128    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,350,389
Number of Sequences: 37866
Number of extensions: 4482252
Number of successful extensions: 25920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 1191
Number of HSP's that attempted gapping in prelim test: 16088
Number of HSP's gapped (non-prelim): 6277
length of query: 1700
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1584
effective length of database: 13,855,062
effective search space: 21946418208
effective search space used: 21946418208
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.