Guide to the Human Genome
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Search of human proteins with 239743688

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo
sapiens]
         (400 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo ...   820   0.0  
gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo ...   820   0.0  
gi|239755029 PREDICTED: hypothetical protein [Homo sapiens]           312   3e-85
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      62   1e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        56   7e-08
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      55   1e-07
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            54   2e-07
gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]            53   6e-07
gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]            53   6e-07
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    52   7e-07
gi|169206171 PREDICTED: hypothetical protein [Homo sapiens]            52   1e-06
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ...    51   2e-06
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ...    50   3e-06
gi|61966741 TMF regulated nuclear protein [Homo sapiens]               50   3e-06
gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]            50   4e-06
gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]            50   4e-06
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    50   5e-06
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    50   5e-06
gi|188536004 zinc finger protein 469 [Homo sapiens]                    49   6e-06
gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]            49   1e-05
gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]             49   1e-05
gi|122937321 UNC homeobox [Homo sapiens]                               49   1e-05
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       48   1e-05
gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo ...    48   2e-05
gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo ...    48   2e-05
gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]            47   2e-05
gi|120587019 zinc finger protein 318 [Homo sapiens]                    47   2e-05
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    47   3e-05
gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]             47   4e-05

>gi|239749538 PREDICTED: hypothetical protein XP_002347080 [Homo
           sapiens]
          Length = 400

 Score =  820 bits (2118), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60
           MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS
Sbjct: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60

Query: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120
           ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT
Sbjct: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120

Query: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180
           PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG
Sbjct: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240
           GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS
Sbjct: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300
           PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA
Sbjct: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300

Query: 301 EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE 360
           EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE
Sbjct: 301 EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE 360

Query: 361 NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG 400
           NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG
Sbjct: 361 NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG 400


>gi|239743688 PREDICTED: hypothetical protein XP_002342946 [Homo
           sapiens]
          Length = 400

 Score =  820 bits (2118), Expect = 0.0
 Identities = 400/400 (100%), Positives = 400/400 (100%)

Query: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60
           MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS
Sbjct: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60

Query: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120
           ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT
Sbjct: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120

Query: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180
           PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG
Sbjct: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240
           GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS
Sbjct: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300
           PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA
Sbjct: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300

Query: 301 EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE 360
           EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE
Sbjct: 301 EFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHE 360

Query: 361 NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG 400
           NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG
Sbjct: 361 NRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG 400


>gi|239755029 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 183

 Score =  312 bits (800), Expect = 3e-85
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60
           MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS
Sbjct: 1   MVHWSQGVSGRASARVSLEPSTHAWEFQIPSLGRNLHVSPGTVLSDLQPLGITFPVFENS 60

Query: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120
           ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT
Sbjct: 61  ERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT 120

Query: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAP 153
           PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAP
Sbjct: 121 PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAP 153


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 107/378 (28%), Positives = 128/378 (33%), Gaps = 70/378 (18%)

Query: 83   PAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLG 142
            P  RG Q PP    P   + G+      +G +A     P   G     G  GER   GL 
Sbjct: 682  PGERGVQGPPGPAGPRGAN-GAPGNDGAKG-DAGAPGAPGSQGAPGLQGMPGERGAAGLP 739

Query: 143  PPRG-------RGLSTAPPPSSLR-LLPPTPRPFPPAPAGGKGEGG--GKESAVLWKGAE 192
             P+G       +G   +P    +R L  P   P P    G KGE G  G       +GA 
Sbjct: 740  GPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAP 799

Query: 193  GG-GEKGNRNMA--AAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP 249
            G  GE G    A  A P G   +  A+ + G    +     P PA P+ P   I    AP
Sbjct: 800  GDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAP 859

Query: 250  GRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGAC--------AARLGGRG----TGRA 297
            G      +     A G   A G   R   P P G          A + GG+G    TG A
Sbjct: 860  GAKGARGSAGPPGATGFPGAAG---RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPA 916

Query: 298  RR-AEFRVAGPRGVAEEAESG-----------------------------RGWRSWPSFS 327
             R  E    GP G A E  S                              RG R +P   
Sbjct: 917  GRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLP 976

Query: 328  AVSG--GGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFG--G 383
              SG  G + P  A   RG   P  PP +A    E     S R   PG     GR G  G
Sbjct: 977  GPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGE-----SGREGAPGAEGSPGRDGSPG 1031

Query: 384  GRGAEG-AGSGLPRGGRG 400
             +G  G  G   P G  G
Sbjct: 1032 AKGDRGETGPAGPPGAPG 1049



 Score = 58.9 bits (141), Expect = 8e-09
 Identities = 89/343 (25%), Positives = 116/343 (33%), Gaps = 45/343 (13%)

Query: 68  PQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT-----PR 122
           P AK  N     + +P   GA+ P     P     G    +   G+   K  T     P 
Sbjct: 394 PGAKGANGAPGIAGAPGFPGARGPSGPQGPGG-PPGPKGNSGEPGAPGSKGDTGAKGEPG 452

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG-- 180
           P GV    G  GE   +G     G                PT  P PP   GG G  G  
Sbjct: 453 PVGVQGPPGPAGEEGKRGARGEPG----------------PTGLPGPPGERGGPGSRGFP 496

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240
           G +     KG    GE+G+    A P G P       + GL   + L        P +P 
Sbjct: 497 GADGVAGPKGP--AGERGSPG-PAGPKGSPGEAGRPGEAGLPGAKGLT-----GSPGSPG 548

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACA--ARLGGRGTGRAR 298
           P  +        + G         G   ARG       P P+GA     + G RG     
Sbjct: 549 PDGKTGPPGPAGQDG----RPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPP 604

Query: 299 RAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRA 358
            A     GP G  ++ E+G      P+  A   G + P  +   +G   P  PP  A + 
Sbjct: 605 GA----VGPAG--KDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658

Query: 359 HENRLRTSARGLGPGDRRGDGRFGGGRGAEG-AGSGLPRGGRG 400
            E  +       GP   RG+  F G RG +G  G   PRG  G
Sbjct: 659 GEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANG 701



 Score = 45.8 bits (107), Expect = 7e-05
 Identities = 90/322 (27%), Positives = 112/322 (34%), Gaps = 65/322 (20%)

Query: 91  PPERFLPSSVSAGSAARTLRRGSEARK--AQTPRPAGVAQGSGGGGERWLQGLGPPRG-R 147
           P ER  P +     A     RG++     A  P P G A   G  G    +G   P+G R
Sbjct: 307 PGERGRPGAPGPAGA-----RGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPR 361

Query: 148 GLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPL 207
           G   +  P  +R       P PP PAG  G  G         GA+G       N A    
Sbjct: 362 G---SEGPQGVR-----GEPGPPGPAGAAGPAGN-------PGADGQPGAKGANGAPGIA 406

Query: 208 GDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEA 267
           G P    A+  +G            P  P  P         PG            + G+ 
Sbjct: 407 GAPGFPGARGPSG------------PQGPGGP---------PGPKGNSGEPGAPGSKGDT 445

Query: 268 AARGLWRRKPAPC----PRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSW 323
            A+G    +P P     P G  A   G RG  R       + GP G       G G R +
Sbjct: 446 GAKG----EPGPVGVQGPPGP-AGEEGKRG-ARGEPGPTGLPGPPG----ERGGPGSRGF 495

Query: 324 PSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGL--GPGDRRGDGRF 381
           P    V+ G + P     S G A P+  P  A R  E  L   A+GL   PG    DG+ 
Sbjct: 496 PGADGVA-GPKGPAGERGSPGPAGPKGSPGEAGRPGEAGL-PGAKGLTGSPGSPGPDGKT 553

Query: 382 G--GGRGAEG-AGSGLPRGGRG 400
           G  G  G +G  G   P G RG
Sbjct: 554 GPPGPAGQDGRPGPPGPPGARG 575



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 94/350 (26%), Positives = 115/350 (32%), Gaps = 54/350 (15%)

Query: 69  QAKAINPHHTASLSPAGRGAQ--RPPERFLPSSVSAG--SAARTLRRGSEARKAQ-TPRP 123
           Q  A +P       PAG   +  +P E+ +P  + A   S AR  R     R  Q  P P
Sbjct: 634 QGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGP 693

Query: 124 AGVAQGSGGGGERWLQG-LGPPRGRGLSTAPPPSSLRLLPPTPRPFP--PAPAGGKGEGG 180
           AG    +G  G    +G  G P   G   AP    +    P  R     P P G +G+ G
Sbjct: 694 AGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGM----PGERGAAGLPGPKGDRGDAG 749

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240
            K       GA+G   K        P+G P    A    G             + PS P+
Sbjct: 750 PK-------GADGSPGKDGVRGLTGPIGPPGPAGAPGDKG------------ESGPSGPA 790

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGA--CAARLGGRGTGRAR 298
                  APG             AG   A G    K  P   GA   A   G  G     
Sbjct: 791 GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGP---- 846

Query: 299 RAEFRVAGPRGV-----AEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPR 353
                 AGP G      A  A+  RG    P  +   G      P G S G A P  PP 
Sbjct: 847 ------AGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPS-GNAGPPGPPG 899

Query: 354 VARRAHENRLRTSARGLG-PGDRRGDGRFG--GGRGAEGAGSGLPRGGRG 400
            A +      R      G PG+    G  G  G +G+ GA    P G  G
Sbjct: 900 PAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG--PAGAPG 947



 Score = 37.7 bits (86), Expect = 0.019
 Identities = 81/317 (25%), Positives = 103/317 (32%), Gaps = 49/317 (15%)

Query: 98  SSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQG-LGPPRGRGLSTAPPPS 156
           + V  G        GSE+   Q     GV    G  G R  +G  GPP   G+   P   
Sbjct: 84  AEVPEGECCPVCPDGSESPTDQ--ETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGL- 140

Query: 157 SLRLLPPTPRPFPPAPAGGKGEGGGKESAVLW---KGAEGG-------GEKGNRNMAAAP 206
                 P P P PP P G  G GG     + +   + + GG       G  G R +   P
Sbjct: 141 ------PGP-PGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPP 193

Query: 207 LGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGE 266
            G P  +  Q   G            P  P A  P        G         +    GE
Sbjct: 194 -GAPGPQGFQGPPG-----------EPGEPGASGPM-------GPRGPPGPPGKNGDDGE 234

Query: 267 AAARGLWRRKPAPCPRGACA-ARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPS 325
           A   G    +  P P+GA       G    +  R    + G +G A  A    G +  P 
Sbjct: 235 AGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPA----GPKGEPG 290

Query: 326 FSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARG-LGPGDRRGDGRFGGG 384
               +G      P G    +  P  P     R ++    T A G  GP    G   F G 
Sbjct: 291 SPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDG--ATGAAGPPGPTGPAGPPGFPGA 348

Query: 385 RGAEG-AGSGLPRGGRG 400
            GA+G AG   PRG  G
Sbjct: 349 VGAKGEAGPQGPRGSEG 365


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 55.8 bits (133), Expect = 7e-08
 Identities = 86/351 (24%), Positives = 124/351 (35%), Gaps = 66/351 (18%)

Query: 58   ENSERSSRHL-----PQA--KAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLR 110
            E S RSS H      P A  KA    + +  SP      R P R   SS S+      L 
Sbjct: 1373 EQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLP 1432

Query: 111  RGSEARKAQTPRPAGVAQGSGGGGERWLQGLGP-----PR--GRGLSTAPPPSSLRLLPP 163
            R + +R++++    G+  GSG      L G  P     PR   RG S        + LP 
Sbjct: 1433 R-TPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQ 1491

Query: 164  TPRPFPPAPAGGK---------GEGGGKESAVLWKGA------EGGGEKGNRNMAAAPLG 208
            TPRP   +P+  +          E  G ES+V  K        +      ++ +   P  
Sbjct: 1492 TPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSA 1551

Query: 209  DPA-REAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEA 267
             P  R  + +    + +    L  R    S+P    +  L+P RSR G++   +      
Sbjct: 1552 SPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD----- 1606

Query: 268  AARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFS 327
                    KP   PR           +G     E +   PR +   + SG          
Sbjct: 1607 --------KPRAAPRAQ---------SGSDSSPEPKAPAPRALPRRSRSGS--------- 1640

Query: 328  AVSGGGESPDPAGCSRGKAAPEEPP--RVARRAHENRLRTSARGLGPGDRR 376
              S  G  P P G S  +++PE PP  R ARR   +      +   P  RR
Sbjct: 1641 --SSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRR 1689



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 37/137 (27%), Positives = 50/137 (36%), Gaps = 5/137 (3%)

Query: 250 GRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRG 309
           GRSR  A     ++      +    R  +P  R + +A+  GR     RR   R     G
Sbjct: 482 GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPG 541

Query: 310 VAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARG 369
            +    + R  RS    SA  G   S  PA  +RG++    P R  R       R  +R 
Sbjct: 542 WSRSRNTQRRGRSR---SARRGRSHSRSPA--TRGRSRSRTPARRGRSRSRTPARRRSRS 596

Query: 370 LGPGDRRGDGRFGGGRG 386
             P  RR   R    RG
Sbjct: 597 RTPTRRRSRSRTPARRG 613



 Score = 33.5 bits (75), Expect = 0.35
 Identities = 73/313 (23%), Positives = 104/313 (33%), Gaps = 54/313 (17%)

Query: 78   TASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERW 137
            T + +P G+ ++    + L    SA    R+    S   KA+T  P      SG   E  
Sbjct: 1527 TVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVD 1586

Query: 138  LQG-LGPPRGRGLSTAPPPSSLRLLP-------PTPRPFPPAPAGGKGEGGGKESAVLWK 189
             +  L P R R  S+       R  P        +P P  PAP            A+  +
Sbjct: 1587 SKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPR-----------ALPRR 1635

Query: 190  GAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP 249
               G   KG           P+ E + +        P     R    S+P P+ +    P
Sbjct: 1636 SRSGSSSKGR---------GPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPP 1686

Query: 250  GR--SRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGP 307
             R  SR    LT +       AR   R + A     + +     R   R RR+   V+ P
Sbjct: 1687 RRRSSRSSPELTRK-------ARLSRRSRSA-----SSSPETRSRTPPRHRRSP-SVSSP 1733

Query: 308  RGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSA 367
               AE++ S R  RS            SP     SR   +P   PR  +R+     R   
Sbjct: 1734 EP-AEKSRSSRRRRS----------ASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782

Query: 368  RGLGPGDRRGDGR 380
            R     DR G  +
Sbjct: 1783 RTTRRRDRSGSSQ 1795



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 71/310 (22%), Positives = 101/310 (32%), Gaps = 41/310 (13%)

Query: 68   PQAKAIN------PHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTP 121
            P A A+N      P   A+LS  G G         P++ +  S++RT +  + A     P
Sbjct: 2290 PTAPAVNLAGARTPAALAALSLTGSGTP-------PTAANYPSSSRTPQAPASANLVG-P 2341

Query: 122  RPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGG 181
            R A         G R    L P        AP  S   L  P        P        G
Sbjct: 2342 RSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR------VPLSAYERVSG 2395

Query: 182  KESAVLWKGAEGG---GEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSA 238
            + S  L   A             M +     P+    QA +      P +  PR  +PSA
Sbjct: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ-SLLPPAQDQPRSPVPSA 2454

Query: 239  PSPRIRCFLA-----PGRSRV--GAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGG 291
             S + RC +A      G   +  GA  T   +AG+          PAP   G   + +G 
Sbjct: 2455 FSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGD---HNGMLSVPAP---GVPHSDVGE 2508

Query: 292  RGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGC----SRGKAA 347
                   +    +A  +   E   S     S  S S+ S    S   +G     S G + 
Sbjct: 2509 PPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL 2568

Query: 348  PEEPPRVARR 357
            P +P    +R
Sbjct: 2569 PVQPEVALKR 2578


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 100/369 (27%), Positives = 125/369 (33%), Gaps = 67/369 (18%)

Query: 59  NSERSSRHLPQAKAIN--PHHTASLSPAG-RGAQRPPERFLPSSV-SAGSAARTLRRGSE 114
           N E+     P  K  N  P    +  P G RGA  P ER  P    +AG+      RGS+
Sbjct: 272 NGEKGETGAPGLKGENGLPGENGAPGPMGPRGA--PGERGRPGLPGAAGARGNDGARGSD 329

Query: 115 ARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPF-----P 169
            +    P P G A   G  G +    +GP    G + AP         P P+       P
Sbjct: 330 GQPGP-PGPPGTAGFPGSPGAKG--EVGPAGSPGSNGAPGQRG----EPGPQGHAGAQGP 382

Query: 170 PAPAGGKGEGGGK--------ESAVLWKGAEGGGEKGNRNMA---AAPLGDPAREAAQAQ 218
           P P G  G  GGK          A    GA G       N A       G+P +  A+ +
Sbjct: 383 PGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGE 442

Query: 219 TGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPA 278
            G R  R         +P  P        A G      +  E  A G   A G    + A
Sbjct: 443 PGPRGER-----GEAGIPGVPG-------AKGEDGKDGSPGEPGANGLPGAAG---ERGA 487

Query: 279 PCPRGACAAR-LGGRGTGRARRAEFRVAGPRGVAEE-----AESGRGWRSWPSFSAVSGG 332
           P  RG      + G       R     AGPRG A E        G G R  P      G 
Sbjct: 488 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 333 GESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGA-G 391
              P P G S+G++    PP  +               GP  + G   F G +G +GA G
Sbjct: 548 DGKPGPPG-SQGESGRPGPPGPS---------------GPRGQPGVMGFPGPKGNDGAPG 591

Query: 392 SGLPRGGRG 400
               RGG G
Sbjct: 592 KNGERGGPG 600



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 88/297 (29%), Positives = 97/297 (32%), Gaps = 59/297 (19%)

Query: 121  PRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180
            P PAG     G GG   L G+  PRG       P       PP P  FP AP G  GE G
Sbjct: 770  PGPAGQPGDKGEGGAPGLPGIAGPRG------SPGERGETGPPGPAGFPGAP-GQNGEPG 822

Query: 181  GK-ESAVLWKGAEGG-----GEKGNRNMAAAP-----------LGDPAREAAQAQTGLRR 223
            GK E     +  EGG     G  G    A  P            G P         GL  
Sbjct: 823  GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAGFPGARGLPG 882

Query: 224  RRPLELVPRPALPSA-------PSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRK 276
                   P P  PS        P P      APG   V     +    GE  + G     
Sbjct: 883  PPGSNGNPGPPGPSGSPGKDGPPGPAGNTG-APGSPGVSGPKGDAGQPGEKGSPGAQGPP 941

Query: 277  PAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESP 336
             AP P G  A   G RG          +AGP G+        G R  P    V G    P
Sbjct: 942  GAPGPLG-IAGITGARG----------LAGPPGMP-------GPRGSPGPQGVKGESGKP 983

Query: 337  DPAGCS--RGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFG--GGRGAEG 389
               G S  RG   P+  P +A  A E       R   PG     GR G  GG+G  G
Sbjct: 984  GANGLSGERGPPGPQGLPGLAGTAGE-----PGRDGNPGSDGLPGRDGSPGGKGDRG 1035



 Score = 52.0 bits (123), Expect = 9e-07
 Identities = 78/305 (25%), Positives = 97/305 (31%), Gaps = 62/305 (20%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGR----GLSTAPPPSSLRLLPPTP------------- 165
           P G+    G  GER   G   PRG     G    P    +R +P +P             
Sbjct: 496 PNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPG 555

Query: 166 ------RPFPPAPAGGKGEGG--GKESAVLWKGAEG-GGEKGNRNMAAAPLGDPAREAAQ 216
                 RP PP P+G +G+ G  G        GA G  GE+G       P G P +    
Sbjct: 556 SQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPG-GPGPQGPPGKNGET 614

Query: 217 AQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRK 276
              G            P  P+ P         PG   +          GE    G    +
Sbjct: 615 GPQG------------PPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPG----E 658

Query: 277 PAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESP 336
           P P          GG+G   A        GP G+A                 + GG   P
Sbjct: 659 PGPKGDAGAPGAPGGKGDAGAPGER----GPPGLA-------------GAPGLRGGAGPP 701

Query: 337 DPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGA-GSGLP 395
            P G  +G A P  PP  A       +     GLG    +GD    GG GA+G  G   P
Sbjct: 702 GPEG-GKGAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760

Query: 396 RGGRG 400
           RG  G
Sbjct: 761 RGPTG 765



 Score = 31.6 bits (70), Expect = 1.3
 Identities = 74/273 (27%), Positives = 89/273 (32%), Gaps = 50/273 (18%)

Query: 163 PTPRPFPPAPAGGKGEGGGKESAVLWKGAEG-GGEKGNRNMAAAPLGDPAREAAQAQTGL 221
           P   P PP P G  G  G   S     G +G  GE G     A P G P    A   +G 
Sbjct: 175 PAGPPGPPGPPGTSGHPGSPGS----PGYQGPPGEPGQ----AGPSGPPGPPGAIGPSGP 226

Query: 222 --------RRRRPLEL-VPRP-------ALPSAPSPR-IRCFLA----PGRSRVGAALTE 260
                   R  RP E  +P P        +P  P  +  R F       G +       E
Sbjct: 227 AGKDGESGRPGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE 286

Query: 261 EQAAGEAAARGLWRRKPAPCPRG--ACAARLGGRGTGRARRAEFRVA--GPRGVA----- 311
               GE  A G    + AP  RG        G RG   AR ++ +    GP G A     
Sbjct: 287 NGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGS 346

Query: 312 EEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLG 371
             A+   G    P  +   G    P P G   G   P  PP +      N        +G
Sbjct: 347 PGAKGEVGPAGSPGSNGAPGQRGEPGPQG-HAGAQGPPGPPGI------NGSPGGKGEMG 399

Query: 372 PGDRRGDGRFGGGRGAEG--AGSGLP--RGGRG 400
           P    G     G RG  G    +G P  RGG G
Sbjct: 400 PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAG 432



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 31/125 (24%), Positives = 37/125 (29%), Gaps = 6/125 (4%)

Query: 121  PRPAGVAQGSGGGGERWLQGL----GPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGK 176
            P  AG A   G  G     GL    G P G+G             P  P P  P    GK
Sbjct: 1001 PGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGK 1060

Query: 177  GEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALP 236
                G+       GA G            P GD      +   G++  R       P  P
Sbjct: 1061 SGDRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFP--GNPGAP 1118

Query: 237  SAPSP 241
             +P P
Sbjct: 1119 GSPGP 1123



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 34/111 (30%), Positives = 40/111 (36%), Gaps = 20/111 (18%)

Query: 83   PAG-RGAQRP--PERFLPSSVSAGSAARTLRRGSEARKAQ--TPRPAGVAQGSGGGGERW 137
            PAG RGA  P  P      +   G+A     RG         +P PAG     G  G   
Sbjct: 1078 PAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAG 1137

Query: 138  LQG----LGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKES 184
             +G     GPP   G S  P P             PP P G +GE G + S
Sbjct: 1138 PRGPVGPSGPPGKDGTSGHPGPIG-----------PPGPRGNRGERGSEGS 1177


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 80/321 (24%), Positives = 115/321 (35%), Gaps = 35/321 (10%)

Query: 101 SAGSAARTLRR--------GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTA 152
           S G   + LRR        G++ R A T      A+G GG G + L G  P  GRG    
Sbjct: 266 SRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRG---- 321

Query: 153 PPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVL-----WKGAEGGGEKGNRNMAAAP- 206
                 +      +    A AG K  GGG++ A +      K     G+K  R  A+A  
Sbjct: 322 ----GKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAG 377

Query: 207 -----LGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEE 261
                 GD        + G  R++P    PR     AP+ + R   +    R G    + 
Sbjct: 378 AKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKS 437

Query: 262 QAAGEAAARGLW-RRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGW 320
           +     +  G   RR+     + A  A    RG  +  R +   AG +      +S  G 
Sbjct: 438 RGGKSRSGGGKKPRRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGK 497

Query: 321 RSWPSFSAVSGGGESPDPAGC-SRGKAAP-EEPPRVA---RRAHENRLRTSARGLGPGDR 375
             W         GE    AG  SRG+  P  + P VA    R   ++ R   + +  G  
Sbjct: 498 NLWRRGQKAEAAGEKATAAGAKSRGRKQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGAT 557

Query: 376 RGDGRFGGGRGAEGAGSGLPR 396
              G  GG + + G G   PR
Sbjct: 558 SHGG--GGNKQSRGGGGNKPR 576



 Score = 53.5 bits (127), Expect = 3e-07
 Identities = 91/383 (23%), Positives = 135/383 (35%), Gaps = 77/383 (20%)

Query: 55  PVFENSERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAART------ 108
           P ++N  R ++  P AK           P G G+++P  R   ++ S G  +R+      
Sbjct: 402 PRWQNPRRRAQKAPAAK-----------PRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKP 450

Query: 109 LRRGSEARKA----------------QTPRPAGVAQGSGG-----GGERWLQGLGPPRGR 147
            RRG +AR+                 Q    AG     GG     G   W +G       
Sbjct: 451 RRRGQKARQKAAEAGAESRGDKKQGRQKASAAGTKSRGGGLKSHSGKNLWRRGQKAEAAG 510

Query: 148 GLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK----GAEGGGEKGNRNMA 203
             +TA    S       PR   PA AG K   GG +S    K    GA   G  GN+   
Sbjct: 511 EKATAAGAKSRGR--KQPRRQKPAVAGAKSRVGGSKSRQRQKAVAAGATSHGGGGNKQSR 568

Query: 204 AAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQA 263
               G+  R+  Q     + R   +                    PG  +  A +T+ ++
Sbjct: 569 GGG-GNKPRQWGQTAAAAKTRGGGDK------------------QPGWQKAAAGVTKSRS 609

Query: 264 AGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSW 323
                 +  WR+K A    GA + +   R  G+   A    A   G       G+  R W
Sbjct: 610 GD--GGKKAWRQKAAGT--GAKSRKKPWR-RGQKDAAAAEKAWATGATSRGSGGKQPR-W 663

Query: 324 PSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGD----- 378
              +A   G ES   A   +   A ++P R   ++  +  + +A G+ P  RRG      
Sbjct: 664 QKPAAA--GSESSAAAAVGQEAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLG 721

Query: 379 -GRFGGGRGAEGAGSGLPRGGRG 400
             R GGG  + G+G    RG  G
Sbjct: 722 KSRGGGGAKSRGSGGAKSRGSGG 744



 Score = 53.1 bits (126), Expect = 4e-07
 Identities = 69/255 (27%), Positives = 91/255 (35%), Gaps = 36/255 (14%)

Query: 174 GGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQT---GLRRRRPLELV 230
           G KG   GKE+   W+ A G G   NR       G   ++AA A T   G R R+P    
Sbjct: 75  GQKGAVAGKEARQHWQKAAGAGGAENR-------GGGEQKAAAAGTKSLGGRGRKPRRRG 127

Query: 231 PRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLG 290
            + A   +  PR R   +            ++AA  A  +     KP         +R G
Sbjct: 128 QKAAATGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSG 187

Query: 291 ---------GRG----TGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPD 337
                     RG     GR R A+ R    RG     +  R   +     +  GGG+ P 
Sbjct: 188 KKPRRRGAKSRGDEDKKGRQREAKSRFGKTRG-GRRKKHRRPKPAAGGAKSRRGGGKKPQ 246

Query: 338 PAGCSRGKAAPEEPPRV--ARRAHENRLRTSAR--GLGPGDRRGDGRFG--------GGR 385
                  KAA     RV  +R   + +LR   +   L    RRG    G        GGR
Sbjct: 247 KQRRRGQKAATGGKSRVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGR 306

Query: 386 GAEGAGSGLPRGGRG 400
           G +  G   PR GRG
Sbjct: 307 GPKSLGGQNPRWGRG 321



 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 81/341 (23%), Positives = 111/341 (32%), Gaps = 81/341 (23%)

Query: 103 GSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLP 162
           G   +  RRG +A    + +P   AQ S   G +        RG G   A          
Sbjct: 118 GRGRKPRRRGQKAAATGSKKPRWRAQKSAAAGSK-------NRGAGAQKAA--------- 161

Query: 163 PTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLR 222
                   A AG K +GG K       GA+    K  R   A   GD  ++  Q +   R
Sbjct: 162 --------AAAGVKSQGGEKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSR 213

Query: 223 ------RRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRK 276
                  RR     P+PA   A S          R   G    +++  G+ AA G   + 
Sbjct: 214 FGKTRGGRRKKHRRPKPAAGGAKS----------RRGGGKKPQKQRRRGQKAATG--GKS 261

Query: 277 PAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVS----GG 332
                RG    +L  +G   A     R        + A  GRG R   S    +     G
Sbjct: 262 RVGKSRGGGDKKLRRQGQNAALAGAKRRGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRG 321

Query: 333 GESP----------DPAGCSRGKAAPEEPPRVARRAHENRLR------------TSARGL 370
           G+ P            AG  RG    ++   V  ++ + + R              A+  
Sbjct: 322 GKKPRRRGQKATKAAAAGTKRGGGGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSR 381

Query: 371 GPGD--------RRGDGR-----FGGGRGAEGAGSGLPRGG 398
           G GD        RRGDGR         R A+ A +  PRGG
Sbjct: 382 GGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAPAAKPRGG 422


>gi|169213235 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 76/272 (27%), Positives = 98/272 (36%), Gaps = 32/272 (11%)

Query: 130 SGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK 189
           +G G + W +    PRG   + AP     R+  P P P PP P GG        + +   
Sbjct: 38  AGAGSKLWRR----PRGAVSAGAPGSPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPG 93

Query: 190 GAEGGGEKGNRNMAAAPLGDPARE--AAQAQTGLRRRRPLELVPRPALPS-APSPRIRCF 246
                G  G R   +   G   R   +A A +  +R  P      PAL + +P P     
Sbjct: 94  AFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSPGPASPPR 153

Query: 247 LAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAG 306
            +PG  R G+     +A G + A    R      P GA      G G+ R R+ +     
Sbjct: 154 ASPG-GRPGS-----EARGRSGAECARRVPLHHGPPGA-----SGVGSERDRKFQLHQTP 202

Query: 307 PRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSR--GKAAPEEPPRVARRAHENRLR 364
            RG      SG   R     S V+     P  A  SR  G+A  E P R  RR       
Sbjct: 203 ARGPPFPGISGM-TRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPR----- 256

Query: 365 TSARGLGPGDRRGDGRFGGGRGAEGAGSGLPR 396
                  PG   G G  GGG  A   G GL R
Sbjct: 257 ------APGRAGGGGPPGGGIPACSIGPGLAR 282



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 67/257 (26%), Positives = 83/257 (32%), Gaps = 38/257 (14%)

Query: 82  SPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQ------GSGGGGE 135
           SP  R +  PP    P      S +   R G       +P P G         GS G   
Sbjct: 59  SPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLR 118

Query: 136 RWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGG 195
                L   +  G + A  P +LR   P P   P A  GG+             G+E  G
Sbjct: 119 CSAAALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGR------------PGSEARG 166

Query: 196 EKGNRNMAAAPL--GDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCF-----LA 248
             G       PL  G P         G  R R  +L   PA    P P I        + 
Sbjct: 167 RSGAECARRVPLHHGPPGASG----VGSERDRKFQLHQTPA-RGPPFPGISGMTRGPVVL 221

Query: 249 PGRSR-----VGAALTEE--QAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAE 301
            G +R      GA+ +    +A GE  AR L RR  AP   G      GG          
Sbjct: 222 SGVNRQHRWPPGASPSRSLGEAGGERPARAL-RRPRAPGRAGGGGPPGGGIPACSIGPGL 280

Query: 302 FRVAGPRGVAEEAESGR 318
            R+A   G+    ES R
Sbjct: 281 ARLAALGGLPSILESSR 297


>gi|169212744 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 308

 Score = 52.8 bits (125), Expect = 6e-07
 Identities = 76/272 (27%), Positives = 98/272 (36%), Gaps = 32/272 (11%)

Query: 130 SGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK 189
           +G G + W +    PRG   + AP     R+  P P P PP P GG        + +   
Sbjct: 38  AGAGSKLWRR----PRGAVSAGAPGSPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPG 93

Query: 190 GAEGGGEKGNRNMAAAPLGDPARE--AAQAQTGLRRRRPLELVPRPALPS-APSPRIRCF 246
                G  G R   +   G   R   +A A +  +R  P      PAL + +P P     
Sbjct: 94  AFVSPGPLGRRASCSGRAGSAGRLRCSAAALSAAQRGGPARAQVPPALRTFSPGPASPPR 153

Query: 247 LAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAG 306
            +PG  R G+     +A G + A    R      P GA      G G+ R R+ +     
Sbjct: 154 ASPG-GRPGS-----EARGRSGAECARRVPLHHGPPGA-----SGVGSERDRKFQLHQTP 202

Query: 307 PRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSR--GKAAPEEPPRVARRAHENRLR 364
            RG      SG   R     S V+     P  A  SR  G+A  E P R  RR       
Sbjct: 203 ARGPPFPGISGM-TRGPVVLSGVNRQHRWPPGASPSRSLGEAGGERPARALRRPR----- 256

Query: 365 TSARGLGPGDRRGDGRFGGGRGAEGAGSGLPR 396
                  PG   G G  GGG  A   G GL R
Sbjct: 257 ------APGRAGGGGPPGGGIPACSIGPGLAR 282



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 67/257 (26%), Positives = 83/257 (32%), Gaps = 38/257 (14%)

Query: 82  SPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQ------GSGGGGE 135
           SP  R +  PP    P      S +   R G       +P P G         GS G   
Sbjct: 59  SPLYRVSAPPPAPPPPPPPGGPSRSERPRAGLRPGAFVSPGPLGRRASCSGRAGSAGRLR 118

Query: 136 RWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGG 195
                L   +  G + A  P +LR   P P   P A  GG+             G+E  G
Sbjct: 119 CSAAALSAAQRGGPARAQVPPALRTFSPGPASPPRASPGGR------------PGSEARG 166

Query: 196 EKGNRNMAAAPL--GDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCF-----LA 248
             G       PL  G P         G  R R  +L   PA    P P I        + 
Sbjct: 167 RSGAECARRVPLHHGPPGASG----VGSERDRKFQLHQTPA-RGPPFPGISGMTRGPVVL 221

Query: 249 PGRSR-----VGAALTEE--QAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAE 301
            G +R      GA+ +    +A GE  AR L RR  AP   G      GG          
Sbjct: 222 SGVNRQHRWPPGASPSRSLGEAGGERPARAL-RRPRAPGRAGGGGPPGGGIPACSIGPGL 280

Query: 302 FRVAGPRGVAEEAESGR 318
            R+A   G+    ES R
Sbjct: 281 ARLAALGGLPSILESSR 297


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 52.4 bits (124), Expect = 7e-07
 Identities = 101/393 (25%), Positives = 128/393 (32%), Gaps = 83/393 (21%)

Query: 70  AKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARK------AQTPRP 123
           A A + HH A  +P  R A       L + V +GS A     G  A        A  P P
Sbjct: 35  ASAAHHHHLAPRTPEVRAAAAGA---LGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPP 91

Query: 124 AGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPT------------------- 164
           AG A+  GGG +R   G   PR   +   P P + +L PP                    
Sbjct: 92  AGRARPGGGGPQR--PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAG 149

Query: 165 PRPFP---------------------PAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMA 203
           P P P                     P P  G G G GK +        G G     N +
Sbjct: 150 PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPA--------GPGAAQTLNGS 201

Query: 204 AAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRC--FLAPGRSRVGAALTEE 261
           AA L   +  AA     L    P  L+P P  P+AP   I+   F+        AA +  
Sbjct: 202 AALLN--SHHAAAPAVSLVNNGPAALLPLPK-PAAPGTVIQTPPFVGAAAPPAPAAPSPP 258

Query: 262 QAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWR 321
            A   AA        P P P  A  AR  G   G    A   V  P        +G    
Sbjct: 259 AAPAPAAPAA---APPPPPPAPATLARPPGHPAGPPTAAP-AVPPPAAAQNGGSAGAAPA 314

Query: 322 SWPSFSAVSGGGESPDPAGCSRGKAAP----EEPPRVARRAHENRLRTSARG-------- 369
             P+    +G    P P G +    AP    E P RV + A       +A G        
Sbjct: 315 PAPAAGGPAGVSGQPGP-GAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASM 373

Query: 370 -LGPGDRRG-DGRFGGGRGAEGAGSGLPRGGRG 400
            +GP  +            A G  +GLP+G  G
Sbjct: 374 VIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAG 406


>gi|169206171 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 466

 Score = 51.6 bits (122), Expect = 1e-06
 Identities = 78/254 (30%), Positives = 92/254 (36%), Gaps = 33/254 (12%)

Query: 85  GRGAQRPPERFLPSSVSAGSAARTLRRGSEARKA--QTPRPAGVAQGSGGGGERWLQGLG 142
           G     PP R L +     + AR   RGSE R     T  P+ V  G  G   R   G+ 
Sbjct: 207 GGSGTPPPPRALWNRHGGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGHGGVQ 266

Query: 143 PPR-------GRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGG 195
             R         G  T P PS  R   P PR   P PA  +G GGG     L     G G
Sbjct: 267 RQRFSAPSSHSTGARTLPTPSRARPGKPAPRGSAP-PARLRGGGGGSGLTQLVGSGRGSG 325

Query: 196 --EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAP-SPRIRCFLAPGRS 252
                  +  A   G  A        G+   RPL     PA  S P SP +R F      
Sbjct: 326 VTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLS---SPAPQSPPRSPSVRAF----GP 378

Query: 253 RVGAA-LTEEQAAGEAAARGLWRRKPAPCPRGA---CAARLGGRGTGRARRAEFRVAGPR 308
           R+GA  L+  QA   AA  G+    P+P        C    GG      RRAE    G R
Sbjct: 379 RLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQRCEGCGGGSQPFAGRRAE---RGKR 435

Query: 309 GVAEEAESGRGWRS 322
           G      +G  WR+
Sbjct: 436 G------AGVPWRT 443



 Score = 42.7 bits (99), Expect = 6e-04
 Identities = 93/387 (24%), Positives = 129/387 (33%), Gaps = 83/387 (21%)

Query: 29  IPSLGRNLHVSPGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGR-- 86
           +PSLG        T LS   P    FP    ++   R +P+    + +HT    PAG   
Sbjct: 20  LPSLGEKAL----TALSHQNP---EFPQIARNDCWDR-VPRGSVTDSNHT----PAGLDC 67

Query: 87  GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146
           G  RP            S + T RR  +A +A    P+   + S      W +      G
Sbjct: 68  GPTRP------------SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115

Query: 147 RGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVL------WKGAEGGGEKGNR 200
            GL  A                 PAP+G +  GG   ++ L      W  + GGG   + 
Sbjct: 116 PGLDCAGSA--------------PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRASHS 161

Query: 201 NMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTE 260
              A   G        ++ G RR+ PL L P           ++      R   G   + 
Sbjct: 162 GPRAGTPGG----GRSSRAGARRKTPLSLCP-----------LKLRKGSSRRCQGLGSSW 206

Query: 261 EQAAGEAAARGLWRRKPAPCPRGACAARLGGRGT------GRARRAEFRVAGPRGVAEEA 314
             +      R LW R       GA  AR   RG+      G        +AG  G     
Sbjct: 207 GGSGTPPPPRALWNRH-----GGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARG 261

Query: 315 ESGRGWRSWPSFSAVSGGGES-PDPAGCSRGKAAP--EEPPRVARRAHENRLRTSARGLG 371
             G   + + + S+ S G  + P P+    GK AP    PP         RLR    G G
Sbjct: 262 HGGVQRQRFSAPSSHSTGARTLPTPSRARPGKPAPRGSAPPA--------RLRGGGGGSG 313

Query: 372 PGDRRGDGRFGGGRGAEGAGSGLPRGG 398
                G GR  G   + G  +   R G
Sbjct: 314 LTQLVGSGRGSGVTHSVGTHALATRRG 340


>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
           sapiens]
          Length = 647

 Score = 50.8 bits (120), Expect = 2e-06
 Identities = 81/262 (30%), Positives = 98/262 (37%), Gaps = 38/262 (14%)

Query: 96  LPSSVSAGSAARTLRRGSEARKAQTPRP---AGVAQGSGGGGERWLQGLGPPRGRGLSTA 152
           LP  +S  SAA      +  R   + RP    G A G G  GE    G+G  RG    TA
Sbjct: 268 LPRLLSMPSAAARPCGAALPRSGFSGRPRGRGGAAAGRGSRGEHPACGVGLARG----TA 323

Query: 153 PPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAR 212
           P P+S   L   PR      AGG      +        A   G++  R+ A     +PAR
Sbjct: 324 PQPASTWALAARPR------AGGTWTSRFEAQRGC---AHQDGQRRTRDGAGNHASEPAR 374

Query: 213 EAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCF--LAPGRSRVGAALTEEQAAGEAAAR 270
             +      RR+RP  L PR +L   P  R  C      G +R G A     A     AR
Sbjct: 375 VWSPPP---RRQRPRRL-PRASLQEEPKRRPPCARPSGAGPAREGPAAWPGGAPTPPHAR 430

Query: 271 GLWRRK-PAPCPR---------GACAARLGGRG--TGRARRAEFRVAGPRGVAEEAESGR 318
              RR+ P P PR         G  A    GRG   G   RA  R A  RG    A S  
Sbjct: 431 PTGRRQDPEPGPRAPRGGPASSGWHAGSAAGRGWDPGGGSRARRRAARGRGCLRSARSSP 490

Query: 319 GWRSWPSFSAV----SGGGESP 336
             R   S  +V    S  G+ P
Sbjct: 491 HARPLGSSRSVRLLRSAAGKGP 512



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 56/201 (27%), Positives = 71/201 (35%), Gaps = 31/201 (15%)

Query: 91  PPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLS 150
           PP R  P         R L R S   + +   P     G+G   E      GP    G +
Sbjct: 379 PPRRQRP---------RRLPRASLQEEPKRRPPCARPSGAGPARE------GPAAWPGGA 423

Query: 151 TAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLG-- 208
             PP +        P P P AP GG    G    +   +G + GG    R  AA   G  
Sbjct: 424 PTPPHARPTGRRQDPEPGPRAPRGGPASSGWHAGSAAGRGWDPGGGSRARRRAARGRGCL 483

Query: 209 DPAREAAQAQTGLRRRRPLELVPRPA--LPSAPSPRIRCFLAPG-----RSRVGAALTEE 261
             AR +  A+  L   R + L+   A   PS  S  +R  +  G      SR G   T  
Sbjct: 484 RSARSSPHARP-LGSSRSVRLLRSAAGKGPSLDSREVRVLIERGCQWWFLSRNGVDYT-- 540

Query: 262 QAAGEAAARGLWRRKPAPCPR 282
                +  RGL R   AP PR
Sbjct: 541 -TGPRSEQRGLAR---APLPR 557


>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
           sapiens]
          Length = 647

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 81/262 (30%), Positives = 97/262 (37%), Gaps = 38/262 (14%)

Query: 96  LPSSVSAGSAARTLRRGSEARKAQTPRP---AGVAQGSGGGGERWLQGLGPPRGRGLSTA 152
           LP  +S  SAA      +  R   + RP    G A G G  GE    G+G  RG    TA
Sbjct: 268 LPRLLSMPSAAARPCGAALPRSGFSGRPRGRGGAAAGRGSRGEHPACGVGLARG----TA 323

Query: 153 PPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAR 212
           P P+S   L   PR      AGG      +        A   G++  R+ A     +PAR
Sbjct: 324 PQPASTWALAARPR------AGGTWTSRFEAQRGC---AHQDGQRRTRDGAGNHASEPAR 374

Query: 213 EAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCF--LAPGRSRVGAALTEEQAAGEAAAR 270
             +      RR+RP  L PR +L   P  R  C      G +R G A     A     AR
Sbjct: 375 VWSPPP---RRQRPRRL-PRASLQEEPKRRPPCARPSGAGPAREGPAAWPGGAPTPPHAR 430

Query: 271 GLWRRK-PAPCPR---------GACAARLGGRG--TGRARRAEFRVAGPRGVAEEAESGR 318
              RR+ P P PR         G  A    GRG   G   RA  R A  RG    A S  
Sbjct: 431 PTGRRQDPEPGPRAPRGGPASSGWHAGSAAGRGWDPGGGSRARRRAARGRGCLRSARSSP 490

Query: 319 GWRSWPSFSAV----SGGGESP 336
             R   S  +V    S  G  P
Sbjct: 491 HARPLGSSRSVRLLRSAAGRGP 512



 Score = 35.8 bits (81), Expect = 0.070
 Identities = 56/201 (27%), Positives = 71/201 (35%), Gaps = 31/201 (15%)

Query: 91  PPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLS 150
           PP R  P         R L R S   + +   P     G+G   E      GP    G +
Sbjct: 379 PPRRQRP---------RRLPRASLQEEPKRRPPCARPSGAGPARE------GPAAWPGGA 423

Query: 151 TAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLG-- 208
             PP +        P P P AP GG    G    +   +G + GG    R  AA   G  
Sbjct: 424 PTPPHARPTGRRQDPEPGPRAPRGGPASSGWHAGSAAGRGWDPGGGSRARRRAARGRGCL 483

Query: 209 DPAREAAQAQTGLRRRRPLELVPRPA--LPSAPSPRIRCFLAPG-----RSRVGAALTEE 261
             AR +  A+  L   R + L+   A   PS  S  +R  +  G      SR G   T  
Sbjct: 484 RSARSSPHARP-LGSSRSVRLLRSAAGRGPSLDSREVRVLIERGCQWWFLSRNGVDYT-- 540

Query: 262 QAAGEAAARGLWRRKPAPCPR 282
                +  RGL R   AP PR
Sbjct: 541 -TGPRSEQRGLAR---APLPR 557


>gi|61966741 TMF regulated nuclear protein [Homo sapiens]
          Length = 227

 Score = 50.4 bits (119), Expect = 3e-06
 Identities = 67/204 (32%), Positives = 82/204 (40%), Gaps = 40/204 (19%)

Query: 143 PPRGRGLSTAPPPSSLRLLP-PTPRPFPPAPAGGKGEGGGKESAVL--WK----GAEGGG 195
           PPR    S+ PPP +  L P PTP   PP P       G  E   L  W+    G  G  
Sbjct: 25  PPRDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQRWRQGASGIAGLA 84

Query: 196 EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRI----RCFL---- 247
             G  + AAA  G  A E A+A     RRR LE+  R  L S    R+    R FL    
Sbjct: 85  GPGGGSGAAAGAGGRALELAEA-----RRRLLEVEGRRRLVSELESRVLQLHRVFLAAEL 139

Query: 248 -----APGRSRVGAALTEEQ----AAGEAAARGLWR-RKPAPCPRGACAARLGG---RGT 294
                A   SR+   + + +    A G    +G  R R+  P    A A  LGG    G 
Sbjct: 140 RLAHRAESLSRLSGGVAQAELYLAAHGSRLKKGPRRGRRGRPPALLASALGLGGCVPWGA 199

Query: 295 GRARR-------AEFRVAGPRGVA 311
           GR RR       + FR + PRG A
Sbjct: 200 GRLRRGHGPEPDSPFRRSPPRGPA 223



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 57/199 (28%), Positives = 70/199 (35%), Gaps = 27/199 (13%)

Query: 215 AQAQTGLRRRRPLELVPRPAL-PSAPSPRIRCFLAPGRS---------RVGAALTEEQAA 264
           AQ  T  +R  P    P P+  P  P+P +     PG+S           GAA  +E   
Sbjct: 13  AQEGTAEQRSPPPPRDPMPSSQPPPPTPTLTPTPTPGQSPPLPDAAGASAGAAEDQELQR 72

Query: 265 GEAAARGLWRRKPAPCPRGACAARLGGRGT--GRARRAEFRVAGPRGVAEEAESG----- 317
               A G+      P      AA  GGR      ARR    V G R +  E ES      
Sbjct: 73  WRQGASGI-AGLAGPGGGSGAAAGAGGRALELAEARRRLLEVEGRRRLVSELESRVLQLH 131

Query: 318 --------RGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARG 369
                   R      S S +SGG    +    + G    ++ PR  RR     L  SA G
Sbjct: 132 RVFLAAELRLAHRAESLSRLSGGVAQAELYLAAHGSRL-KKGPRRGRRGRPPALLASALG 190

Query: 370 LGPGDRRGDGRFGGGRGAE 388
           LG     G GR   G G E
Sbjct: 191 LGGCVPWGAGRLRRGHGPE 209


>gi|169206489 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 82/278 (29%), Positives = 99/278 (35%), Gaps = 38/278 (13%)

Query: 61  ERSSRH--LPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAAR-------TLRR 111
           ERSSR   L  +KA      AS  P  R A   P     +    G   R        +R 
Sbjct: 286 ERSSREPLLDPSKAAR----ASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341

Query: 112 GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPA 171
                + + PR +G A     G E W +        G  T P PS  R   P PR   P 
Sbjct: 342 DLSTAEEEDPR-SGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP- 399

Query: 172 PAGGKGEGGGKESAVLWKGAEGGG--EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLEL 229
           PA  +G GGG     L     G G       +  A   G  A        G+   RPL  
Sbjct: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLS- 458

Query: 230 VPRPALPSAP-SPRIRCFLAPGRSRVGAA-LTEEQAAGEAAARGLWRRKPAPCPRGA--- 284
              PA  S P SP +R F      R+GA  L+  QA   AA  G+    P+P        
Sbjct: 459 --SPAPQSPPRSPSVRAF----GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQR 512

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRS 322
           C    GG      RRAE    G RG      +G  WR+
Sbjct: 513 CEGCGGGSQPFAGRRAE---RGKRG------AGVPWRT 541



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 93/372 (25%), Positives = 125/372 (33%), Gaps = 77/372 (20%)

Query: 29  IPSLGRNLHVSPGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGR-- 86
           +PSLG        T LS   P    FP    ++   R +P+    + +HT    PAG   
Sbjct: 20  LPSLGEKAL----TALSHQNP---EFPQIARNDCWDR-VPRGSVTDSNHT----PAGLDC 67

Query: 87  GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146
           G  RP            S + T RR  +A +A    P+   + S      W +      G
Sbjct: 68  GPTRP------------SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115

Query: 147 RGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK-----GAEGGGEKGNRN 201
            GL  A                 PAP+G +  GG   ++ L +      A GGG +G+ +
Sbjct: 116 PGLDCAGSA--------------PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHS 161

Query: 202 MAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEE 261
              A  G P      ++ G RR+ PL L P           ++      R   G   +  
Sbjct: 162 GPRA--GTPGG-GRSSRAGARRKTPLSLCP-----------LKLRKGSSRRCQGLGSSWG 207

Query: 262 QAAGEAAARGLWRRKPAPCPRGACAARLGGRGT------GRARRAEFRVAGPRGVAEEAE 315
            +      R LW R       GA  AR   RG+      G        +AG  G      
Sbjct: 208 GSGTPPPPRALWNRH-----GGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262

Query: 316 SG--RGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPG 373
            G  R   S PS  + SGG     P G  R    P   P  A RA        A    P 
Sbjct: 263 GGVQRQRFSAPSSHSTSGG----RPTG-ERSSREPLLDPSKAARASALPTARVAHASPPS 317

Query: 374 DRRGDGRFGGGR 385
                 R GGG+
Sbjct: 318 LAAAQWRLGGGK 329



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 81/328 (24%), Positives = 107/328 (32%), Gaps = 59/328 (17%)

Query: 85  GRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPP 144
           GRG+   P    P         R+ R G+  +   +  P  + +GS     R  QGLG  
Sbjct: 156 GRGSHSGPRAGTPGG------GRSSRAGARRKTPLSLCPLKLRKGSS----RRCQGLGSS 205

Query: 145 RGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAA 204
            G G  T PPP +L                    GG   +    +G+E     G+    +
Sbjct: 206 WG-GSGTPPPPRAL----------------WNRHGGAAGARAQVRGSEKRACPGSTLPPS 248

Query: 205 APLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP-GRSRVGAALTEEQA 263
           + L       A+   G++R+R           SAPS        P G       L +   
Sbjct: 249 SVLAGCVGTRARGHGGVQRQRF----------SAPSSHSTSGGRPTGERSSREPLLDPSK 298

Query: 264 AGEAAARGLWRRKPAPCPRGACAA-RLGG--------RGTGRARRAEFRVAGPRG--VAE 312
           A  A+A    R   A  P  A A  RLGG        +G  R   +      PR     E
Sbjct: 299 AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALE 358

Query: 313 EAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAP--EEPPRVARRAHENRLRTSARGL 370
            A+    W         SG    P P+    GK AP    PP         RLR    G 
Sbjct: 359 PAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPA--------RLRGGGGGS 410

Query: 371 GPGDRRGDGRFGGGRGAEGAGSGLPRGG 398
           G     G GR  G   + G  +   R G
Sbjct: 411 GLTQLVGSGRGSGVTHSVGTHALATRRG 438


>gi|169205942 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 564

 Score = 50.1 bits (118), Expect = 4e-06
 Identities = 82/278 (29%), Positives = 99/278 (35%), Gaps = 38/278 (13%)

Query: 61  ERSSRH--LPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAAR-------TLRR 111
           ERSSR   L  +KA      AS  P  R A   P     +    G   R        +R 
Sbjct: 286 ERSSREPLLDPSKAAR----ASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRT 341

Query: 112 GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPA 171
                + + PR +G A     G E W +        G  T P PS  R   P PR   P 
Sbjct: 342 DLSTAEEEDPR-SGRALEPAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAP- 399

Query: 172 PAGGKGEGGGKESAVLWKGAEGGG--EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLEL 229
           PA  +G GGG     L     G G       +  A   G  A        G+   RPL  
Sbjct: 400 PARLRGGGGGSGLTQLVGSGRGSGVTHSVGTHALATRRGSRAPRPVGVLRGVPHFRPLS- 458

Query: 230 VPRPALPSAP-SPRIRCFLAPGRSRVGAA-LTEEQAAGEAAARGLWRRKPAPCPRGA--- 284
              PA  S P SP +R F      R+GA  L+  QA   AA  G+    P+P        
Sbjct: 459 --SPAPQSPPRSPSVRAF----GPRLGAGRLSCPQAPRAAALPGIAVLAPSPAHDWGGQR 512

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRS 322
           C    GG      RRAE    G RG      +G  WR+
Sbjct: 513 CEGCGGGSQPFAGRRAE---RGKRG------AGVPWRT 541



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 93/372 (25%), Positives = 125/372 (33%), Gaps = 77/372 (20%)

Query: 29  IPSLGRNLHVSPGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGR-- 86
           +PSLG        T LS   P    FP    ++   R +P+    + +HT    PAG   
Sbjct: 20  LPSLGEKAL----TALSHQNP---EFPQIARNDCWDR-VPRGSVTDSNHT----PAGLDC 67

Query: 87  GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146
           G  RP            S + T RR  +A +A    P+   + S      W +      G
Sbjct: 68  GPTRP------------SGSLTTRRPRDAGEAAVSGPSRQRRTSRARTALWGRRSRRAAG 115

Query: 147 RGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWK-----GAEGGGEKGNRN 201
            GL  A                 PAP+G +  GG   ++ L +      A GGG +G+ +
Sbjct: 116 PGLDCAGSA--------------PAPSGAQSCGGPAPASALRRPLTQWDASGGGGRGSHS 161

Query: 202 MAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEE 261
              A  G P      ++ G RR+ PL L P           ++      R   G   +  
Sbjct: 162 GPRA--GTPGG-GRSSRAGARRKTPLSLCP-----------LKLRKGSSRRCQGLGSSWG 207

Query: 262 QAAGEAAARGLWRRKPAPCPRGACAARLGGRGT------GRARRAEFRVAGPRGVAEEAE 315
            +      R LW R       GA  AR   RG+      G        +AG  G      
Sbjct: 208 GSGTPPPPRALWNRH-----GGAAGARAQVRGSEKRACPGSTLPPSSVLAGCVGTRARGH 262

Query: 316 SG--RGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPG 373
            G  R   S PS  + SGG     P G  R    P   P  A RA        A    P 
Sbjct: 263 GGVQRQRFSAPSSHSTSGG----RPTG-ERSSREPLLDPSKAARASALPTARVAHASPPS 317

Query: 374 DRRGDGRFGGGR 385
                 R GGG+
Sbjct: 318 LAAAQWRLGGGK 329



 Score = 37.4 bits (85), Expect = 0.024
 Identities = 81/328 (24%), Positives = 107/328 (32%), Gaps = 59/328 (17%)

Query: 85  GRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPP 144
           GRG+   P    P         R+ R G+  +   +  P  + +GS     R  QGLG  
Sbjct: 156 GRGSHSGPRAGTPGG------GRSSRAGARRKTPLSLCPLKLRKGSS----RRCQGLGSS 205

Query: 145 RGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAA 204
            G G  T PPP +L                    GG   +    +G+E     G+    +
Sbjct: 206 WG-GSGTPPPPRAL----------------WNRHGGAAGARAQVRGSEKRACPGSTLPPS 248

Query: 205 APLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP-GRSRVGAALTEEQA 263
           + L       A+   G++R+R           SAPS        P G       L +   
Sbjct: 249 SVLAGCVGTRARGHGGVQRQRF----------SAPSSHSTSGGRPTGERSSREPLLDPSK 298

Query: 264 AGEAAARGLWRRKPAPCPRGACAA-RLGG--------RGTGRARRAEFRVAGPRG--VAE 312
           A  A+A    R   A  P  A A  RLGG        +G  R   +      PR     E
Sbjct: 299 AARASALPTARVAHASPPSLAAAQWRLGGGKRKPTVLKGAVRTDLSTAEEEDPRSGRALE 358

Query: 313 EAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAP--EEPPRVARRAHENRLRTSARGL 370
            A+    W         SG    P P+    GK AP    PP         RLR    G 
Sbjct: 359 PAQGSELWARAERHGGSSGARTLPTPSRARPGKPAPRGSAPPA--------RLRGGGGGS 410

Query: 371 GPGDRRGDGRFGGGRGAEGAGSGLPRGG 398
           G     G GR  G   + G  +   R G
Sbjct: 411 GLTQLVGSGRGSGVTHSVGTHALATRRG 438


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 84/332 (25%), Positives = 107/332 (32%), Gaps = 51/332 (15%)

Query: 78   TASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT--PRPAGVAQGSGGGGE 135
            T  + P G       +  +     AGSA     RG+   + +T  P PAG A   G  G+
Sbjct: 788  TGPIGPPGPAGANGEKGEVGPPGPAGSAGA---RGAPGERGETGPPGPAGFAGPPGADGQ 844

Query: 136  RWLQG-LGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGG 194
               +G  G    +G + AP P       P+  P P  P G  G  G +       GA+G 
Sbjct: 845  PGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGPTGVTGPKGAR-------GAQGP 892

Query: 195  GEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRV 254
                    AA  +G P                      P  P  P P        G+   
Sbjct: 893  PGATGFPGAAGRVGPPGSNG-----------------NPGPPGPPGPS-------GKDGP 928

Query: 255  GAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEA 314
              A  +    G A   GL  + PA  P         G            +AG RG+    
Sbjct: 929  KGARGDSGPPGRAGEPGL--QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG-L 985

Query: 315  ESGRGWRSWPSFSAVSG--GGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGP 372
               RG R +P     SG  G +    A   RG   P  PP +   A E     S    GP
Sbjct: 986  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 1045

Query: 373  GDRRGDGRFGGGRGAEGA----GSGLPRGGRG 400
              R G     G RG  GA    G+  P G  G
Sbjct: 1046 PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1077



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 91/352 (25%), Positives = 117/352 (33%), Gaps = 63/352 (17%)

Query: 103 GSAARTLRRGSEARKAQ-----TPRPAGVAQGSGGGGERWLQGL-GPPRGRGLSTAP--- 153
           G A  T  RG E  +       TP   G A  SG  G   + G  G     G++ AP   
Sbjct: 375 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 434

Query: 154 -------PPSSLRLLPPTPRPFPPAPAGGKGEGG--GKESAVLWKGAEG-GGEKGNRNM- 202
                  P  +   L P  +   P  AG KGE G  G+      +GA G  GE+G R   
Sbjct: 435 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 494

Query: 203 ----AAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAAL 258
                  P+G P    A    G   +  L          AP  R    LA  +   G   
Sbjct: 495 GEPGGVGPIGPPGERGAPGNRGFPGQDGLA-----GPKGAPGERGPSGLAGPKGANGDPG 549

Query: 259 TEEQAAGEAAARGLWRRKPAPCPRGACA--------ARLGGRGT--GRARRAEFRVAGPR 308
              +  G   ARGL  R     P+G            R G  G    R +       GP+
Sbjct: 550 RPGEP-GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 608

Query: 309 GV-AEEAESGR-------GWRSWPSFSAVSGGGESPDPAGCS--------------RGKA 346
           G   E  ++G        G R  P     +G    P PAG +              +G  
Sbjct: 609 GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 668

Query: 347 APEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGA-GSGLPRG 397
            P  PP    +  +  +   A   G    RG+  F G RG+ GA G   PRG
Sbjct: 669 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 720



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 80/300 (26%), Positives = 98/300 (32%), Gaps = 49/300 (16%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLS--TAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180
           P G     G  G    QGL  PRG   +  T  P  +     P     PP   G  GE G
Sbjct: 697 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 756

Query: 181 --------GKESAVLWKGAEGG-GEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVP 231
                   G    V  KG EG  G+ G R +   P+G P    A  + G       E+ P
Sbjct: 757 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGPAGANGEKG-------EVGP 808

Query: 232 RPALPSA---PSPRIRCFLAP----GRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGA 284
                SA    +P  R    P    G +    A  +  A GE    G      AP P+G 
Sbjct: 809 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 868

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRG 344
             A      TG        V GP+G        RG +  P  +   G      P G S G
Sbjct: 869 SGAPGPQGPTG--------VTGPKG-------ARGAQGPPGATGFPGAAGRVGPPG-SNG 912

Query: 345 KAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEG----AGSGLPRGGRG 400
              P  PP  + +      R  +   GP  R G+    G  G  G     G   P G  G
Sbjct: 913 NPGPPGPPGPSGKDGPKGARGDS---GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 969



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 77/301 (25%), Positives = 94/301 (31%), Gaps = 66/301 (21%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGK 182
           PAG     G  G++  +G   PRGR      P +      P P P PP P G  G GG  
Sbjct: 127 PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN------PGP-PGPPGPPGPPGLGG-- 177

Query: 183 ESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPR--PALPSAPS 240
                             N AA   G    +A  AQ G+ +     + PR  P    AP 
Sbjct: 178 ------------------NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 219

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300
           P+       G         E   +G    RG     P P  +       G  G    +  
Sbjct: 220 PQ-------GFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPG----KAG 264

Query: 301 EFRVAGPRGV-----AEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEP-PRV 354
           E    GP+G             +G R +P      G   +P   G S        P P  
Sbjct: 265 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 324

Query: 355 ARRAHENRLRTSARGLGPGDRRGDGRFG-----------GGRGAEGA----GSGLPRGGR 399
            R     R RT   G   G R  DG+ G           GG G  GA    G   P G R
Sbjct: 325 PRGLPGERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 383

Query: 400 G 400
           G
Sbjct: 384 G 384



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 18/189 (9%)

Query: 87   GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146
            GA  PP        S G A  T ++G    +A    P G    SG  G R +QG   PRG
Sbjct: 1068 GAPGPPG-------SPGPAGPTGKQGDRG-EAGAQGPMGP---SGPAGARGIQGPQGPRG 1116

Query: 147  -RGLSTAPPPSSLR----LLPPTPRPFPPAPAGGKGEGG--GKESAVLWKGAEGGGEKGN 199
             +G +  P    L+           P PP P+G +G  G  G        G  G   K  
Sbjct: 1117 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1176

Query: 200  RNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALT 259
             N    P+G P       +TG          P P  P  P   +  F   G    G    
Sbjct: 1177 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1236

Query: 260  EEQAAGEAA 268
            +   A +AA
Sbjct: 1237 QYMRADQAA 1245



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 63/256 (24%), Positives = 76/256 (29%), Gaps = 53/256 (20%)

Query: 170 PAPAGGKGEGGGKESAVLWKGAEG----GGEKGNRNMAAAPLGDPAREAAQAQTGLRRRR 225
           P P G KGE G  +  V  KG  G     GE+G       P GD   +  +   G R R 
Sbjct: 100 PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG-------PRGDRGDKGEKGAPGPRGRD 152

Query: 226 PLELVP-RPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGA 284
                P  P  P  P P       PG   +G     + A G       +  K      G 
Sbjct: 153 GEPGTPGNPGPPGPPGP-------PGPPGLGGNFAAQMAGG-------FDEKAGGAQLGV 198

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRG 344
               +G  G  R         GP+G     +   G    P  S   G    P P G    
Sbjct: 199 MQGPMGPMGP-RGPPGPAGAPGPQGF----QGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 253

Query: 345 KAAPEEPPRVARRAHENRLRTSARGL-------GPGDRRGDGRFGGGRGAEGA------- 390
                +P +   R         ARG        G    RG     G +G  GA       
Sbjct: 254 DGEAGKPGKAGERGPPG--PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 311

Query: 391 ------GSGLPRGGRG 400
                 GS  P G RG
Sbjct: 312 GSPGENGSPGPMGPRG 327


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 49.7 bits (117), Expect = 5e-06
 Identities = 84/332 (25%), Positives = 107/332 (32%), Gaps = 51/332 (15%)

Query: 78   TASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQT--PRPAGVAQGSGGGGE 135
            T  + P G       +  +     AGSA     RG+   + +T  P PAG A   G  G+
Sbjct: 719  TGPIGPPGPAGANGEKGEVGPPGPAGSAGA---RGAPGERGETGPPGPAGFAGPPGADGQ 775

Query: 136  RWLQG-LGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGG 194
               +G  G    +G + AP P       P+  P P  P G  G  G +       GA+G 
Sbjct: 776  PGAKGEQGEAGQKGDAGAPGPQG-----PSGAPGPQGPTGVTGPKGAR-------GAQGP 823

Query: 195  GEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRV 254
                    AA  +G P                      P  P  P P        G+   
Sbjct: 824  PGATGFPGAAGRVGPPGSNG-----------------NPGPPGPPGPS-------GKDGP 859

Query: 255  GAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEA 314
              A  +    G A   GL  + PA  P         G            +AG RG+    
Sbjct: 860  KGARGDSGPPGRAGEPGL--QGPAGPPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVG-L 916

Query: 315  ESGRGWRSWPSFSAVSG--GGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGP 372
               RG R +P     SG  G +    A   RG   P  PP +   A E     S    GP
Sbjct: 917  PGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGP 976

Query: 373  GDRRGDGRFGGGRGAEGA----GSGLPRGGRG 400
              R G     G RG  GA    G+  P G  G
Sbjct: 977  PGRDGAAGVKGDRGETGAVGAPGAPGPPGSPG 1008



 Score = 45.4 bits (106), Expect = 9e-05
 Identities = 91/352 (25%), Positives = 117/352 (33%), Gaps = 63/352 (17%)

Query: 103 GSAARTLRRGSEARKAQ-----TPRPAGVAQGSGGGGERWLQGL-GPPRGRGLSTAP--- 153
           G A  T  RG E  +       TP   G A  SG  G   + G  G     G++ AP   
Sbjct: 306 GEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP 365

Query: 154 -------PPSSLRLLPPTPRPFPPAPAGGKGEGG--GKESAVLWKGAEG-GGEKGNRNM- 202
                  P  +   L P  +   P  AG KGE G  G+      +GA G  GE+G R   
Sbjct: 366 GPRGPPGPQGATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGAR 425

Query: 203 ----AAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAAL 258
                  P+G P    A    G   +  L          AP  R    LA  +   G   
Sbjct: 426 GEPGGVGPIGPPGERGAPGNRGFPGQDGLA-----GPKGAPGERGPSGLAGPKGANGDPG 480

Query: 259 TEEQAAGEAAARGLWRRKPAPCPRGACA--------ARLGGRGT--GRARRAEFRVAGPR 308
              +  G   ARGL  R     P+G            R G  G    R +       GP+
Sbjct: 481 RPGEP-GLPGARGLTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFPGPK 539

Query: 309 GV-AEEAESGR-------GWRSWPSFSAVSGGGESPDPAGCS--------------RGKA 346
           G   E  ++G        G R  P     +G    P PAG +              +G  
Sbjct: 540 GANGEPGKAGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLP 599

Query: 347 APEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGA-GSGLPRG 397
            P  PP    +  +  +   A   G    RG+  F G RG+ GA G   PRG
Sbjct: 600 GPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRG 651



 Score = 39.3 bits (90), Expect = 0.006
 Identities = 80/300 (26%), Positives = 98/300 (32%), Gaps = 49/300 (16%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLS--TAPPPSSLRLLPPTPRPFPPAPAGGKGEGG 180
           P G     G  G    QGL  PRG   +  T  P  +     P     PP   G  GE G
Sbjct: 628 PRGERGFPGERGSPGAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERG 687

Query: 181 --------GKESAVLWKGAEGG-GEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVP 231
                   G    V  KG EG  G+ G R +   P+G P    A  + G       E+ P
Sbjct: 688 AAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTG-PIGPPGPAGANGEKG-------EVGP 739

Query: 232 RPALPSA---PSPRIRCFLAP----GRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGA 284
                SA    +P  R    P    G +    A  +  A GE    G      AP P+G 
Sbjct: 740 PGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGP 799

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRG 344
             A      TG        V GP+G        RG +  P  +   G      P G S G
Sbjct: 800 SGAPGPQGPTG--------VTGPKG-------ARGAQGPPGATGFPGAAGRVGPPG-SNG 843

Query: 345 KAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEG----AGSGLPRGGRG 400
              P  PP  + +      R  +   GP  R G+    G  G  G     G   P G  G
Sbjct: 844 NPGPPGPPGPSGKDGPKGARGDS---GPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEG 900



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 77/301 (25%), Positives = 94/301 (31%), Gaps = 66/301 (21%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGK 182
           PAG     G  G++  +G   PRGR      P +      P P P PP P G  G GG  
Sbjct: 58  PAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGN------PGP-PGPPGPPGPPGLGG-- 108

Query: 183 ESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPR--PALPSAPS 240
                             N AA   G    +A  AQ G+ +     + PR  P    AP 
Sbjct: 109 ------------------NFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPG 150

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRA 300
           P+       G         E   +G    RG     P P  +       G  G    +  
Sbjct: 151 PQ-------GFQGNPGEPGEPGVSGPMGPRG----PPGPPGKPGDDGEAGKPG----KAG 195

Query: 301 EFRVAGPRGV-----AEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEP-PRV 354
           E    GP+G             +G R +P      G   +P   G S        P P  
Sbjct: 196 ERGPPGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMG 255

Query: 355 ARRAHENRLRTSARGLGPGDRRGDGRFG-----------GGRGAEGA----GSGLPRGGR 399
            R     R RT   G   G R  DG+ G           GG G  GA    G   P G R
Sbjct: 256 PRGLPGERGRTGPAG-AAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGAR 314

Query: 400 G 400
           G
Sbjct: 315 G 315



 Score = 38.5 bits (88), Expect = 0.011
 Identities = 51/189 (26%), Positives = 65/189 (34%), Gaps = 18/189 (9%)

Query: 87   GAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRG 146
            GA  PP        S G A  T ++G    +A    P G    SG  G R +QG   PRG
Sbjct: 999  GAPGPPG-------SPGPAGPTGKQGDRG-EAGAQGPMGP---SGPAGARGIQGPQGPRG 1047

Query: 147  -RGLSTAPPPSSLR----LLPPTPRPFPPAPAGGKGEGG--GKESAVLWKGAEGGGEKGN 199
             +G +  P    L+           P PP P+G +G  G  G        G  G   K  
Sbjct: 1048 DKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGPSGPRGPPGPVGPSGKDG 1107

Query: 200  RNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALT 259
             N    P+G P       +TG          P P  P  P   +  F   G    G    
Sbjct: 1108 ANGIPGPIGPPGPRGRSGETGPAGPPGNPGPPGPPGPPGPGIDMSAFAGLGPREKGPDPL 1167

Query: 260  EEQAAGEAA 268
            +   A +AA
Sbjct: 1168 QYMRADQAA 1176



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 63/256 (24%), Positives = 76/256 (29%), Gaps = 53/256 (20%)

Query: 170 PAPAGGKGEGGGKESAVLWKGAEG----GGEKGNRNMAAAPLGDPAREAAQAQTGLRRRR 225
           P P G KGE G  +  V  KG  G     GE+G       P GD   +  +   G R R 
Sbjct: 31  PGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQG-------PRGDRGDKGEKGAPGPRGRD 83

Query: 226 PLELVP-RPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGA 284
                P  P  P  P P       PG   +G     + A G       +  K      G 
Sbjct: 84  GEPGTPGNPGPPGPPGP-------PGPPGLGGNFAAQMAGG-------FDEKAGGAQLGV 129

Query: 285 CAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRG 344
               +G  G  R         GP+G     +   G    P  S   G    P P G    
Sbjct: 130 MQGPMGPMGP-RGPPGPAGAPGPQGF----QGNPGEPGEPGVSGPMGPRGPPGPPGKPGD 184

Query: 345 KAAPEEPPRVARRAHENRLRTSARGL-------GPGDRRGDGRFGGGRGAEGA------- 390
                +P +   R         ARG        G    RG     G +G  GA       
Sbjct: 185 DGEAGKPGKAGERGPPG--PQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGES 242

Query: 391 ------GSGLPRGGRG 400
                 GS  P G RG
Sbjct: 243 GSPGENGSPGPMGPRG 258


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 49.3 bits (116), Expect = 6e-06
 Identities = 93/344 (27%), Positives = 119/344 (34%), Gaps = 73/344 (21%)

Query: 43   VLSDLQPLGITFPVFENSERSSRHL-PQAKAINPHHTASLSP-----AGRGAQ---RPPE 93
            V +D +P G   P   +  +S   + P++KA  P   A+  P       RG     RP  
Sbjct: 867  VFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTPRPGDRGCPARGRPKT 926

Query: 94   RFL---PSSVSAGSAARTLRRGSEARKAQTPRPAG-VAQGSGGGGERWLQGLGPPRGRGL 149
            R L   P+   A S  R  RRG + +  +    +G  A+GSG GG     GL P R  GL
Sbjct: 927  RSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASGLRPRRNDGL 986

Query: 150  STAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGD 209
               PPP      P  PR   P                         +   R   AA L +
Sbjct: 987  GERPPPR-----PRRPRTQAPG---------------------SRADPAPRVPRAAALPE 1020

Query: 210  PAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFL--APGRSRVGAALTEEQAAGEA 267
              R +       RRRR         LP    PR R     A G+  +   + ++    E 
Sbjct: 1021 ETRSS-------RRRR---------LPPRKDPRKRKARGGAWGKELILKIVQQKNRLREY 1064

Query: 268  AARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAG--------PRGVAEEAESGRG 319
                       P PRG      G RG G  R+      G        PR  A +   G G
Sbjct: 1065 DFASESEEDEQPPPRG--PGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDG 1122

Query: 320  WRSWPSFSAVS--GGGESPDPAGCSR----GKAAPEEPPRVARR 357
              + P     S  G G SP   G SR    G AA E  P+ A R
Sbjct: 1123 APANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKCADR 1166



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 90/359 (25%), Positives = 121/359 (33%), Gaps = 60/359 (16%)

Query: 82   SPAGRGAQRPPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGL 141
            S  G G  RPP R     +S GS    L   SE   + T       +G     ER +  +
Sbjct: 3454 SAPGPGEDRPPPRGSSPILSEGSLPALLHLCSEVAPSTT-------KGWPETLERPVDPV 3506

Query: 142  GPP-RGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNR 200
              P RG  L    P +     PP+  PFP A A G+G+     +    +     G  G  
Sbjct: 3507 THPIRGCEL----PSNHQECPPPSLSPFPAALADGRGDCALDGALERPENEASPGSPGPL 3562

Query: 201  NMAAAPLG-DPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALT 259
               A PLG    R  A+ Q    +R PL    +     AP  R RC  AP   +    L 
Sbjct: 3563 LQQALPLGASLPRPGARGQDAEGKRAPLVFSGK---RRAPGARGRC--APDHFQEDHLLQ 3617

Query: 260  EEQ------AAGEAAARGLWRR----KPAPC----------------------PRGACAA 287
            +E+         E   RG + +    KPA C                      PR A  +
Sbjct: 3618 KEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFPVHPRKAVGS 3677

Query: 288  RLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAG---CSRG 344
               G    R      + A P+     +  G G    P     +GGG  P PA     S  
Sbjct: 3678 LAPGE-LARGTENGMKPATPKAKPGPSSQGSG---SPRPGTKTGGGSQPQPASGQLQSET 3733

Query: 345  KAAPEEPPRVARRAHENRL--RTSARGLGPGDRR-GDGRFGGGRGAEGAGSGLPRGGRG 400
               P +P   +R     RL  R  A+    G R  G+    G  G +  G    +  +G
Sbjct: 3734 ATTPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKG 3792



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 39/156 (25%), Positives = 61/156 (39%), Gaps = 21/156 (13%)

Query: 210  PAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAA 269
            P   A   + G++   P +  P P+   + SPR      PG ++ G     + A+G+  +
Sbjct: 3680 PGELARGTENGMKPATP-KAKPGPSSQGSGSPR------PG-TKTGGGSQPQPASGQLQS 3731

Query: 270  R-GLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGR-GWRSWPSFS 327
                   KP+   R     RL  R      +A+    GPR   E+   G  G +     S
Sbjct: 3732 ETATTPAKPSFPSRSPAPERLPARA-----QAKSCTKGPREAGEQGPHGSLGPKEKGESS 3786

Query: 328  AVSGGGESPDPA------GCSRGKAAPEEPPRVARR 357
                 G+ P PA         R  +AP++PPR  R+
Sbjct: 3787 TKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRK 3822



 Score = 32.7 bits (73), Expect = 0.60
 Identities = 47/207 (22%), Positives = 63/207 (30%), Gaps = 40/207 (19%)

Query: 68   PQAKAINPHHTASLSPAGRGAQRPPERFL----------------PSSVSAGSAARTLRR 111
            PQ++   PH      P G  +  P                     P+   AG  +     
Sbjct: 2280 PQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGAGPDSPACLE 2339

Query: 112  GSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGL--STAP-----------PPSSL 158
            G     ++ P   G  +    G  +  +   P  G GL  +TAP           P S  
Sbjct: 2340 GEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHR 2399

Query: 159  RLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQ 218
                 TP+  P  P   K    G +        E G  KG      AP G    E   A 
Sbjct: 2400 NASHQTPQGDPLGPQDLKQRSRGYKKKPA--STENGQWKGQ-----APHGPVTCEVCAAS 2452

Query: 219  ----TGLRRRRPLELVPRPALPSAPSP 241
                 GL R +  +  P P  P+ PSP
Sbjct: 2453 FRSGPGLSRHKARKHRPHPGAPAEPSP 2479



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 40/150 (26%), Positives = 53/150 (35%), Gaps = 21/150 (14%)

Query: 73  INPHHTASLSPAGRGAQRPPERFLPSSV--SAGSAARTLRRGS------EARKAQTPRPA 124
           ++PH T SL P       P E  LPS    +AGS   +L   S       + ++Q P P 
Sbjct: 570 VSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPL 629

Query: 125 GVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFP----PAPAGGKGEGG 180
           G +         +      P+  G S  P P     LP   +P P    P PA G G  G
Sbjct: 630 GPS--------AFFHPPTHPQETG-SPFPSPEPPHSLPTHYQPEPAKAFPFPADGLGAEG 680

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDP 210
             +          G E G   +   P   P
Sbjct: 681 AFQCLEETPFPHEGPEVGRGGLQGFPRAPP 710



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 14/34 (41%), Positives = 18/34 (52%), Gaps = 1/34 (2%)

Query: 142 GPPRGRGLSTAPPPSSL-RLLPPTPRPFPPAPAG 174
           GPP     +  PPP+ L +L  PT  P+P  P G
Sbjct: 421 GPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGG 454


>gi|169207312 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 78/300 (26%), Positives = 114/300 (38%), Gaps = 37/300 (12%)

Query: 97  PSSVS--AGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPP 154
           P+S+S  A  A+   ++   AR+AQ PRP    +       R   GL    GR L     
Sbjct: 85  PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP----PRGRVGLSQAPGRPLGACAR 140

Query: 155 PSSLRLLPPT-PRPFPPAPAGGKGEGG----GKESAVLWKGAEGGGE--------KGNRN 201
              +RL+ P+ PRP  P PA      G    G  ++      +G G         K  + 
Sbjct: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQR 200

Query: 202 MAAAPLGD-PAREAAQAQTGLRRRRPLELV---PRPALPSAPSPRIRCFLAPGRSRVGAA 257
           +AA P  + P     +  +GL    P E      +    + P PR   FL+   S     
Sbjct: 201 VAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPST--RP 258

Query: 258 LTEEQAAGEAAARGLWR--RKPAPCPRGACA-ARLGGRGTGRA---RRAEFRVAGPRGVA 311
           L    ++  A     W   R P+P P  AC   RLG     RA     +    +GP    
Sbjct: 259 LCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKH 318

Query: 312 EEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLG 371
               +     +WP+    +G   +P+PA   RG    + PP  +RR    R+  +AR  G
Sbjct: 319 RTLPAPPAPTAWPA----AGAPGAPNPAESRRGPGPAQGPP--SRRDEPRRVVIAARECG 372


>gi|239750650 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 78/300 (26%), Positives = 114/300 (38%), Gaps = 37/300 (12%)

Query: 97  PSSVS--AGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPP 154
           P+S+S  A  A+   ++   AR+AQ PRP    +       R   GL    GR L     
Sbjct: 85  PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP----PRGRVGLSQAPGRPLGACAR 140

Query: 155 PSSLRLLPPT-PRPFPPAPAGGKGEGG----GKESAVLWKGAEGGGE--------KGNRN 201
              +RL+ P+ PRP  P PA      G    G  ++      +G G         K  + 
Sbjct: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQR 200

Query: 202 MAAAPLGD-PAREAAQAQTGLRRRRPLELV---PRPALPSAPSPRIRCFLAPGRSRVGAA 257
           +AA P  + P     +  +GL    P E      +    + P PR   FL+   S     
Sbjct: 201 VAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPST--RP 258

Query: 258 LTEEQAAGEAAARGLWR--RKPAPCPRGACA-ARLGGRGTGRA---RRAEFRVAGPRGVA 311
           L    ++  A     W   R P+P P  AC   RLG     RA     +    +GP    
Sbjct: 259 LCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKH 318

Query: 312 EEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLG 371
               +     +WP+    +G   +P+PA   RG    + PP  +RR    R+  +AR  G
Sbjct: 319 RTLPAPPAPTAWPA----AGAPGAPNPAESRRGPGPAQGPP--SRRDEPRRVVIAARECG 372


>gi|89037350 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 414

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 78/300 (26%), Positives = 114/300 (38%), Gaps = 37/300 (12%)

Query: 97  PSSVS--AGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPP 154
           P+S+S  A  A+   ++   AR+AQ PRP    +       R   GL    GR L     
Sbjct: 85  PASLSPRAALASAPGQKPQPARQAQLPRPVSGVRPP----PRGRVGLSQAPGRPLGACAR 140

Query: 155 PSSLRLLPPT-PRPFPPAPAGGKGEGG----GKESAVLWKGAEGGGE--------KGNRN 201
              +RL+ P+ PRP  P PA      G    G  ++      +G G         K  + 
Sbjct: 141 AKGIRLVNPSPPRPPEPIPASAAVTSGLTARGPNTSATPGPQKGRGSAERTNHIPKDKQR 200

Query: 202 MAAAPLGD-PAREAAQAQTGLRRRRPLELV---PRPALPSAPSPRIRCFLAPGRSRVGAA 257
           +AA P  + P     +  +GL    P E      +    + P PR   FL+   S     
Sbjct: 201 VAAPPPPERPRVPFCRGSSGLSVPTPPEHAGGRRKKFTRTRPLPRTSSFLSEVPST--RP 258

Query: 258 LTEEQAAGEAAARGLWR--RKPAPCPRGACA-ARLGGRGTGRA---RRAEFRVAGPRGVA 311
           L    ++  A     W   R P+P P  AC   RLG     RA     +    +GP    
Sbjct: 259 LCATSSSHSAPLPFFWSPLRNPSPRPAPACGELRLGRLSPPRADTGGSSSGGCSGPDSKH 318

Query: 312 EEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLG 371
               +     +WP+    +G   +P+PA   RG    + PP  +RR    R+  +AR  G
Sbjct: 319 RTLPAPPAPTAWPA----AGAPGAPNPAESRRGPGPAQGPP--SRRDEPRRVVIAARECG 372


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 84/338 (24%), Positives = 107/338 (31%), Gaps = 38/338 (11%)

Query: 33  GRNLHVSPGTVLSD--LQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGRGAQR 90
           GR  H S  T  S   + P  I     E  E+  R          H    L   GR    
Sbjct: 171 GRPAHNSHPTTCSGEPMDPEEIARKELEKMEKKKRK---------HEKKLLKSQGRHLHS 221

Query: 91  PPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLS 150
           P    L S+ S+ S +     G      + P PA    G+   G        P       
Sbjct: 222 PGGLSLHSAPSSDSDSGG--GGLSPEPPEPPPPAAKGPGAHASGAAGTAPAPPGEPPAPG 279

Query: 151 TAPP---PSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPL 207
           T  P   PS      P PRP  PA       G G   A + +GA G  +    ++ +   
Sbjct: 280 TCDPAFYPSQRSGAGPQPRPGRPADKDAASCGPGAAVAAVERGAAGLPKASPFSVESLLS 339

Query: 208 GDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRC-------------FLAPGRSRV 254
             P R  A +         L+  P   LP AP   I               FL P  +  
Sbjct: 340 DSPPRRKAASNAAAAAAAGLDFAP--GLPCAPRTLIGKGHFLLYPITQPLGFLVPQAALK 397

Query: 255 GAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEA 314
           G A  E        A  +    PA    GA +   G   +  ARR+   VA P      A
Sbjct: 398 GGAGLEPAPKDAPPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASP---GAPA 454

Query: 315 ESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPP 352
            +   +R   S +A  GGG     A    G A P  PP
Sbjct: 455 PAPAPFRDLASAAATEGGGGDCADA----GTAGPAPPP 488



 Score = 34.7 bits (78), Expect = 0.16
 Identities = 35/102 (34%), Positives = 39/102 (38%), Gaps = 11/102 (10%)

Query: 146 GRGLSTAPPPSSLRLLPPTPR--PFPPAPAGG---KGEGGGKESAVLWKGAEGGGEKGNR 200
           G GL  AP  +     PP P   P PPA A      G GG  +SA   +  +     G  
Sbjct: 399 GAGLEPAPKDA-----PPAPAVPPAPPAQASFGAFSGPGGAPDSAFARRSPDAVASPGAP 453

Query: 201 NMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPR 242
             A AP  D A  AA    G          P P  P APSPR
Sbjct: 454 APAPAPFRDLASAAATEGGGGDCADAGTAGPAPP-PPAPSPR 494



 Score = 30.4 bits (67), Expect = 3.0
 Identities = 40/135 (29%), Positives = 50/135 (37%), Gaps = 25/135 (18%)

Query: 48  QPLGITFPVFE-----NSERSSRHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSA 102
           QPLG   P          E + +  P A A+ P   A  + A  GA   P     S+ + 
Sbjct: 385 QPLGFLVPQAALKGGAGLEPAPKDAPPAPAVPP---APPAQASFGAFSGPGGAPDSAFAR 441

Query: 103 GSAARTLRRGSEARKAQTPRP----AGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSL 158
            S       G+ A     P P    A  A   GGGG+    G   P       APPP + 
Sbjct: 442 RSPDAVASPGAPA---PAPAPFRDLASAAATEGGGGDCADAGTAGP-------APPPPAP 491

Query: 159 RLLPPTPRPFPPAPA 173
               P P P PP+PA
Sbjct: 492 S---PRPGPRPPSPA 503


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 94/369 (25%), Positives = 115/369 (31%), Gaps = 57/369 (15%)

Query: 47   LQPLGITFPVFENSERSSRHL--PQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGS 104
            L P G   P  E  E   R L  P     NP       P G      P+         G 
Sbjct: 803  LGPPGPAGPTGEKGEPGPRGLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGE 862

Query: 105  AARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPT 164
                 ++G     A +P P G+A   G  G   + GL   RG    T  PP +       
Sbjct: 863  PGEPGQKGD----AGSPGPQGLAGSPGPHGPNGVPGLKGGRG----TQGPPGATGFPGSA 914

Query: 165  PRPFPPAPAGGKGEGG-----GKESAVLWKGAEGG-GEKGNRNMAAAP-----------L 207
             R  PP PAG  G  G     GKE     +G  G  G  G+R  A  P            
Sbjct: 915  GRVGPPGPAGAPGPAGPLGEPGKEGPPGLRGDPGSHGRVGDRGPAGPPGGPGDKGDPGED 974

Query: 208  GDPAREAAQAQTGLRRRRPLELVP----RPALPSAPSPRIRCFLAPGRSRVGAALTEEQA 263
            G P  +      G   +R +  +P       +P  P P       PG+     A  ++  
Sbjct: 975  GQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPA----GTPGKVGPTGATGDKGP 1030

Query: 264  AGEAAARGLWRRKPAPCPRG-ACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRS 322
             G     G       P P G A      GR      R +    GP G+       +G   
Sbjct: 1031 PGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPGPAGL----PGSQGAPG 1086

Query: 323  WPS-FSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGL-GPGDRRGDGR 380
             P    A    G+  DP     G   P  PP           R   RGL GP   RGD  
Sbjct: 1087 TPGPVGAPGDAGQRGDP-----GSRGPIGPPG----------RAGKRGLPGPQGPRGDKG 1131

Query: 381  FGGGRGAEG 389
              G RG  G
Sbjct: 1132 DHGDRGDRG 1140



 Score = 43.1 bits (100), Expect = 4e-04
 Identities = 78/299 (26%), Positives = 104/299 (34%), Gaps = 50/299 (16%)

Query: 114 EARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFP---- 169
           EA     P P G+    G  GE   +G   PRG   +  PP        P  R FP    
Sbjct: 478 EAGPKGEPGPHGIQGPIGPPGEEGKRG---PRGDPGTVGPPGPVGERGAPGNRGFPGSDG 534

Query: 170 -PAPAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLE 228
            P P G +GE G   S+         G KG++     P G+P    A+  TG        
Sbjct: 535 LPGPKGAQGERGPVGSS---------GPKGSQGDPGRP-GEPGLPGARGLTG-------- 576

Query: 229 LVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAAR 288
               P +   P  ++    APG              G+  + GL      P P+G+    
Sbjct: 577 ---NPGV-QGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGL------PGPKGSS--- 623

Query: 289 LGGRGT-GRARRAEFRVAGPRGV-AEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKA 346
            G  G  G A  A   V G RG   ++ E G      P   A   G + P      +G  
Sbjct: 624 -GDPGKPGEAGNAG--VPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680

Query: 347 APEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLP-----RGGRG 400
            P  PP    +  +  +      +GP   RG+    G RG  G  +GLP      GG G
Sbjct: 681 GPPGPPGEGGKPGDQGVPGDPGAVGPLGPRGERGNPGERGEPGI-TGLPGEKGMAGGHG 738



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 65/277 (23%), Positives = 84/277 (30%), Gaps = 59/277 (21%)

Query: 123 PAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFP--PAPAGGKGEGG 180
           P G+   SG  G   ++G   P G      P        PP P   P  P   G  G  G
Sbjct: 370 PLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGTDGTPG 429

Query: 181 GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPS 240
                   KG  G         +A P G P  + +    G+R         +P  P  P 
Sbjct: 430 A-------KGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIR--------GQPGDPGVPG 474

Query: 241 PRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLG--GRGTGRAR 298
            +                      GEA  +G       P P G     +G  G    R  
Sbjct: 475 FK----------------------GEAGPKG------EPGPHG-IQGPIGPPGEEGKRGP 505

Query: 299 RAEFRVAGPRGVAEE--AESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVAR 356
           R +    GP G   E  A   RG+          G      P G S  K +  +P R   
Sbjct: 506 RGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGE 565

Query: 357 RAHENRLRTSARGL--GPGDRRGDGRFG--GGRGAEG 389
                     ARGL   PG +  +G+ G  G  G +G
Sbjct: 566 PG-----LPGARGLTGNPGVQGPEGKLGPLGAPGEDG 597



 Score = 33.1 bits (74), Expect = 0.46
 Identities = 75/295 (25%), Positives = 93/295 (31%), Gaps = 66/295 (22%)

Query: 120 TPRPAGVAQGSGGGGERWLQGLGPPRG-------RGLSTAPPPSSLRLLP-PTPRPFPPA 171
           TP   G     G  GER + G   P+G       +G          R LP P   P P  
Sbjct: 751 TPGDTGPPGLQGMPGERGIAGTPGPKGDRGGIGEKGAEGTAGNDGARGLPGPLGPPGPAG 810

Query: 172 PAGGKGEGGGKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVP 231
           P G KGE G +   V   G+ G       N     +G    +    Q G++         
Sbjct: 811 PTGEKGEPGPR-GLVGPPGSRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGE------- 862

Query: 232 RPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGG 291
               P  P                    ++  AG    +GL    P P          GG
Sbjct: 863 ----PGEPG-------------------QKGDAGSPGPQGL-AGSPGPHGPNGVPGLKGG 898

Query: 292 RGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEP 351
           RGT           GP G       G   R  P      G   +P PAG   G+   E P
Sbjct: 899 RGT----------QGPPGAT--GFPGSAGRVGP-----PGPAGAPGPAG-PLGEPGKEGP 940

Query: 352 PRVARRAHENRLRTSARGL-----GPGDRRGDGRFGGGRGAEG-AGSGLPRGGRG 400
           P + R    +  R   RG      GPGD +GD    G  G +G  G     G RG
Sbjct: 941 PGL-RGDPGSHGRVGDRGPAGPPGGPGD-KGDPGEDGQPGPDGPPGPAGTTGQRG 993



 Score = 32.3 bits (72), Expect = 0.78
 Identities = 81/333 (24%), Positives = 108/333 (32%), Gaps = 47/333 (14%)

Query: 91  PPERFLP-SSVSAGSAARTLRRGSEARKAQT------------PRPAGVAQGSGGGGERW 137
           PP    P  S + G       RG + +K +             P PAG     G  GER 
Sbjct: 88  PPGECCPVCSQTPGGGNTNFGRGRKGQKGEPGLVPVVTGIRGRPGPAGPPGSQGPRGERG 147

Query: 138 LQGLGPPRG-RGLSTAP-PPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGG 195
            +G   PRG +G+   P  P       P   P  P P  G       + A L + +  G 
Sbjct: 148 PKGRPGPRGPQGIDGEPGVPGQPGAPGPPGHPSHPGP-DGLSRPFSAQMAGLDEKSGLGS 206

Query: 196 EKGNRNMAAAPLGDPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVG 255
           + G    +  P+G    +  Q Q G            P  P  P P     + P  SR  
Sbjct: 207 QVGLMPGSVGPVGPRGPQGLQGQQG-----GAGPTGPPGEPGDPGP-----MGPIGSR-- 254

Query: 256 AALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTG--------RARRAEFRVAGP 307
                E   G+    G   R   P   G  A   G RG          +  R    + GP
Sbjct: 255 ---GPEGPPGKPGEDGEPGRNGNPGEVG-FAGSPGARGFPGAPGLPGLKGHRGHKGLEGP 310

Query: 308 RGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGCSRGKAAPEEPPRVARRAHENRLRTSA 367
           +G  E    G    + P+    + G   P      RG+  P+  P   R AH   +    
Sbjct: 311 KG--EVGAPGSKGEAGPTGPMGAMGPLGPRGMPGERGRLGPQGAPG-QRGAH--GMPGKP 365

Query: 368 RGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGRG 400
             +GP    G   F G  G +G     P G RG
Sbjct: 366 GPMGPLGIPGSSGFPGNPGMKGEAG--PTGARG 396


>gi|239750121 PREDICTED: hypothetical protein XP_002347280 [Homo
           sapiens]
          Length = 402

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 83/307 (27%), Positives = 102/307 (33%), Gaps = 58/307 (18%)

Query: 94  RFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPP----RGRGL 149
           R LPS VS     R  RR +  +  +     G      GG      GLG P       GL
Sbjct: 39  RSLPS-VSGPVRGRAERRPARGKHVRGGGVGGCRDSRAGGSHAAPSGLGVPGDSESALGL 97

Query: 150 STAPPPSSLRL---LPPTPRPFPPA--------------PAGGKGEGGGKESAVLWKGAE 192
               PP SLR+   L   PR  P A              PA      G  +    W+  +
Sbjct: 98  LEPGPPKSLRISVTLGQAPRAGPSAASSAAAGKTPPSRVPAEPSSRRGASKRRESWR-TD 156

Query: 193 GGGEKGNRNMAAAPLG-----DPAREAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFL 247
           G   +  R  A A  G     D  RE       + R     L P  ++ S+ SP      
Sbjct: 157 GERLRSGRGCAGAARGPDASLDTRREGWPRAAVVGRHEARRLKPGVSVSSSLSP------ 210

Query: 248 APGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGTGRARRAEFRVAGP 307
                  G  L    +  E   RG  RR P P P  A A R      GR   A F  +  
Sbjct: 211 -------GPPLQRSSSLNETL-RG--RRPPGPAPAAAGATRGTAAPPGRDPSAWFLDS-- 258

Query: 308 RGVAEEAESGRGWRSWPSFSA--------VSGGGESPDPAGCSRGKAAPEEPPRVARRAH 359
              A    +    RSW  F A         +GGG S    G   G+A   E PR  R + 
Sbjct: 259 ---ASACPTPLAARSWHPFVANKLCGRGKGAGGGASRPKEGVGSGRARAWE-PRGGRESG 314

Query: 360 ENRLRTS 366
            +R R S
Sbjct: 315 RSRRRKS 321


>gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo
           sapiens]
          Length = 347

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 45/163 (27%), Positives = 62/163 (38%), Gaps = 11/163 (6%)

Query: 248 APGRSRVGAALTEEQAAGEAAARGLWRRKPAPCPRGACAARLGGRGT----------GRA 297
           +P   R GA   E Q+    +     R++    PR        GRG            R 
Sbjct: 125 SPEPCRRGAQSMEPQSRAWESQPADGRKQSREAPRSGYEGDGSGRGCRDSGATYPAGARR 184

Query: 298 RRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGGGESPDPAGC-SRGKAAPEEPPRVAR 356
             AE    GP+ + E+  SG   R  P+ +A S    +  P  C   G+ AP  PP  AR
Sbjct: 185 SLAEAERVGPKPLPEQERSGASGRCLPAPAAFSAAAPARRPPACLPEGEDAPVAPPSSAR 244

Query: 357 RAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSGLPRGGR 399
            A  + L   +  L    +RG G      G  G+ +G  RG R
Sbjct: 245 PALPSFLLRPSGYLAARRQRGPGSGAAETGFRGSCAGCGRGLR 287



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 39/118 (33%), Positives = 48/118 (40%), Gaps = 12/118 (10%)

Query: 279 PCPRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPSFSAVSGG---GES 335
           P P+G  A  L GRG          + G  G  E   S   +RS P F+  S       S
Sbjct: 60  PLPKGN-ALLLQGRGY-----TTHPLHGSDGEPETCPSLSPFRSTPGFNRFSLEPTLARS 113

Query: 336 PDPAGCSRGKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEGAGSG 393
              AG   G+A+PE P R   ++ E + R  A    P D R   R     G EG GSG
Sbjct: 114 FTHAGARAGRASPE-PCRRGAQSMEPQSR--AWESQPADGRKQSREAPRSGYEGDGSG 168


>gi|239741753 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 77/267 (28%), Positives = 94/267 (35%), Gaps = 64/267 (23%)

Query: 58  ENSERSSRHLPQAKAINPHHTASLSPAGR--GAQRPPERFLPSSVSAGSAARTLRR---- 111
           E  E+SS  L +A  +     A    AGR  G   PP              +TL+R    
Sbjct: 21  EEEEKSS--LGRAAGVESRRRAGEGAAGRRDGGWGPP--------GGAGDHQTLQRASLL 70

Query: 112 -GSEARKAQTPRPAGVAQGSGGGG--ERWLQGLGPPRGRGLSTAPPPSSL-----RLLPP 163
            G  A K Q   P+  A+G+       + L    PP G GL   PPP +      R L P
Sbjct: 71  PGGSADKDQEREPSLAARGTAPPAPPRQCLPTPCPPLGHGLRPRPPPGTPPPRCPRTLAP 130

Query: 164 TPRPFPPAPAGGKGEGG--GKESAVLWKGAEGGGEKGNRNMAAAPLGDPAREAAQAQTGL 221
            PR   PAP       G  GK +A   +     G +  R+ +  P          AQT L
Sbjct: 131 GPRGLFPAPPPAPARTGPAGKAAADRGRPGPAAGRRVRRSPSFPPF-------LLAQTRL 183

Query: 222 RRRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKPAPCP 281
            R  PL L                 L  G  R+G    E+ A                C 
Sbjct: 184 GRTGPLAL-------------CLLLLLHGAMRLGGGSREKLA----------------CG 214

Query: 282 RGACAARLGGRGTGRARRAEFRVAGPR 308
           R   AAR  GRG G  RRAE   AG R
Sbjct: 215 RAGRAART-GRGEG-GRRAEEEAAGRR 239



 Score = 38.1 bits (87), Expect = 0.014
 Identities = 80/298 (26%), Positives = 97/298 (32%), Gaps = 72/298 (24%)

Query: 110 RRGSEARKAQTPRPAGVAQ----GSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTP 165
           +R  E  K+   R AGV      G G  G R   G GPP G G       +SL       
Sbjct: 18  KREEEEEKSSLGRAAGVESRRRAGEGAAGRRD-GGWGPPGGAGDHQTLQRASL------- 69

Query: 166 RPFPPAPAGGKGEGGGKESAVLWKG-AEGGGEKGNRNMAAAPLGDPAREAAQAQTGLRRR 224
                 P G   +   +E ++  +G A     +        PLG           GLR R
Sbjct: 70  -----LPGGSADKDQEREPSLAARGTAPPAPPRQCLPTPCPPLGH----------GLRPR 114

Query: 225 RPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARGLWRRKP-APC--- 280
            P         P  P PR    LAPG                   RGL+   P AP    
Sbjct: 115 PP---------PGTPPPRCPRTLAPG------------------PRGLFPAPPPAPARTG 147

Query: 281 PRGACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGWRSWPS--------FSAVSGG 332
           P G  AA  G  G    RR     + P  +  +   GR   + P           A+  G
Sbjct: 148 PAGKAAADRGRPGPAAGRRVRRSPSFPPFLLAQTRLGR---TGPLALCLLLLLHGAMRLG 204

Query: 333 GESPDPAGCSR-GKAAPEEPPRVARRAHENRLRTSARGLGPGDRRGDGRFGGGRGAEG 389
           G S +   C R G+AA        RRA E       R   PG  RG  R  GG    G
Sbjct: 205 GGSREKLACGRAGRAARTGRGEGGRRAEEEAAGRRRR-RRPGRTRGIPRAAGGLSRAG 261


>gi|120587019 zinc finger protein 318 [Homo sapiens]
          Length = 2279

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 49/172 (28%), Positives = 73/172 (42%), Gaps = 26/172 (15%)

Query: 56  VFENSERSS--RHLPQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTLRRGS 113
           ++ +S RSS   H P+        +   S +  G   P  R  P    +GS++RT     
Sbjct: 1   MYRSSARSSVSSHRPKDDGGGGPRSGRSSGSSSG---PARRSSPPPPPSGSSSRT----- 52

Query: 114 EARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRP---FPP 170
            AR+ ++P        SG  G R      PPRGR +S +PP +  R  P  PR    FPP
Sbjct: 53  PARRPRSP--------SGHRGRR--ASPSPPRGRRVSPSPPRAR-RGSPSPPRGRRLFPP 101

Query: 171 APAGGKGEGGGKESAVLWKGAEGG--GEKGNRNMAAAPLGDPAREAAQAQTG 220
            PAG +G   G+  A   +   G   G+ G+R  +     D   ++ +   G
Sbjct: 102 GPAGFRGSSRGESRADYARDGRGDHPGDSGSRRRSPGLCSDSLEKSLRITVG 153



 Score = 29.6 bits (65), Expect = 5.0
 Identities = 29/84 (34%), Positives = 39/84 (46%), Gaps = 5/84 (5%)

Query: 91   PPERFLPSSVSAGSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLS 150
            P   FL S  S+G+ A+ L    E+  A    P  +   + GG E  L+G  P     L+
Sbjct: 1372 PLNTFL-SIKSSGTTAKPLPVVKES-SADLLLPPDIISKAFGGEEVILKG-SPEEKVVLA 1428

Query: 151  TAPPPSSL--RLLPPTPRPFPPAP 172
                PS L  ++LPP P P PP P
Sbjct: 1429 EKSEPSHLPEQILPPPPPPPPPPP 1452


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 47.0 bits (110), Expect = 3e-05
 Identities = 96/351 (27%), Positives = 119/351 (33%), Gaps = 82/351 (23%)

Query: 68   PQAKAINPHHTASLSPAGRGAQRPPERFLPSSVSAGSAARTL-RRGSEARKAQTPRPAGV 126
            P   A +P H  S    G  +Q P  R+      A SAA  +  R    RK    +   V
Sbjct: 1057 PTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAASAAMYVPARSGRGRKGPLVKQTKV 1116

Query: 127  AQGSGGGGERWLQGLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPA------------- 173
                   GE       P +G GL  AP P+S    P +P+P PPA A             
Sbjct: 1117 E------GE-------PQKGGGLPPAPSPTS----PASPQP-PPAVAAPSEKNSIPIPTI 1158

Query: 174  ---------GGKGEGGGKESAVLWKGAE--GGGEKGNRNMAAAPLGDPAREAAQAQTGLR 222
                      G+   G    A      E  GGG  G  + + AP   P   +        
Sbjct: 1159 IIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPPSPSP----- 1213

Query: 223  RRRPLELVPRPALPSAPSPRIRCFLAPGRSRVGAALTEEQAAGEAAARG-LWRRKPAPCP 281
                   VP PA PS P+  +      G + VGAA  E     EA  R  L+    A   
Sbjct: 1214 -------VPTPASPSGPA-TLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDE 1265

Query: 282  RGACAARLGGRGTGRARRAEFR----------VAGPRGVAEEAESGRGWRSWPSFSAVSG 331
             G      GG GTG A     R           A P    E A SG G+  + + S   G
Sbjct: 1266 DGGD----GGLGTGAAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYG 1321

Query: 332  GGES---------PDP-AGCSRGKAA-PEEPPRVARRAHENRLRTSARGLG 371
            GG           P P      GKA  P  P  +A  A E  L+ S+ G G
Sbjct: 1322 GGGGSSAFTSFLPPRPLVHPLTGKALDPASPLGLALAARERALKESSEGGG 1372



 Score = 30.0 bits (66), Expect = 3.9
 Identities = 79/306 (25%), Positives = 104/306 (33%), Gaps = 60/306 (19%)

Query: 143  PPRGRGLSTAPPPS--SLRLLPPTPRPFPPAPA--GGKGEGGGKE--------------- 183
            PPR   L+  P PS    R   P+P P  P+P+  G  G GGG                 
Sbjct: 1036 PPR---LALGPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSSQGPALRYFQLPPRAA 1092

Query: 184  SAVLWKGAEGG-GEKGNRNMAAAPLGDPAR----EAAQAQTGLRRRRPLELVPRPA-LPS 237
            SA ++  A  G G KG         G+P +      A + T     +P   V  P+   S
Sbjct: 1093 SAAMYVPARSGRGRKGPLVKQTKVEGEPQKGGGLPPAPSPTSPASPQPPPAVAAPSEKNS 1152

Query: 238  APSPRIRCFLAP-----GRSRVGAAL-----TEEQAAGEAAARGLWRRKPAPC----PRG 283
             P P I    AP     GRS  G++      T+ +  G     G     PAP     P  
Sbjct: 1153 IPIPTI-IIKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGGGGGGS-SPSPAPAMSPVPPS 1210

Query: 284  ACAARLGGRGTGRARRAEFRVAGPRGVAEEAESGRGW-----RSWPSFSAVSGGGESPDP 338
                      +G A   +F       +   A    GW     R    F +   G E    
Sbjct: 1211 PSPVPTPASPSGPA-TLDFTSQFGAALVGAARREGGWQNEARRRSTLFLSTDAGDEDGGD 1269

Query: 339  AGCSRGKAAPEEPPRVARRAHEN--------RLRTSARGLGPGD-RRGDGRFGGGRGAEG 389
             G   G AAP    R ++   E         RL ++  G G G    G   +GGG G+  
Sbjct: 1270 GGLGTG-AAPGPRLRHSKSIDEGMFSAEPYLRLESAGSGAGYGGYGAGSRAYGGGGGSSA 1328

Query: 390  AGSGLP 395
              S LP
Sbjct: 1329 FTSFLP 1334



 Score = 29.3 bits (64), Expect = 6.6
 Identities = 34/115 (29%), Positives = 40/115 (34%), Gaps = 12/115 (10%)

Query: 140  GLGPPRGRGLSTAPPPSSLRLLPPTPRPFPPAPAGGKGEGGGKESAVLWKGAEGGGEKGN 199
            G GPP   G    PPPS  R +PP+P   P A      E  G    VL   A     +  
Sbjct: 1507 GRGPPSEDGPGV-PPPSPRRSVPPSPTS-PRA-----SEENGLPLLVLPPPAPSVDVEDG 1559

Query: 200  RNMAAAPLGDPAR-----EAAQAQTGLRRRRPLELVPRPALPSAPSPRIRCFLAP 249
              +   PL  P       E  ++        PL   P PA P  P P      AP
Sbjct: 1560 EFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAP 1614


>gi|219804203 rabphilin 3A homolog isoform 1 [Homo sapiens]
          Length = 694

 Score = 46.6 bits (109), Expect = 4e-05
 Identities = 42/147 (28%), Positives = 57/147 (38%), Gaps = 8/147 (5%)

Query: 40  PGTVLSDLQPLGITFPVFENSERSSRHLPQAKAINPHHTASLSPAGRGAQR--PPERFLP 97
           P  VL    P+  T P    SE ++   P+  A  P H A     G    R  P ++  P
Sbjct: 162 PKQVLPQPMPIKKTKPQQPVSEPAA---PEQPAPEPKHPARAPARGDSEDRRGPGQKTGP 218

Query: 98  SSVSA---GSAARTLRRGSEARKAQTPRPAGVAQGSGGGGERWLQGLGPPRGRGLSTAPP 154
              SA   G+    +RR SEAR + + R +     SGG G+      G  R   +  + P
Sbjct: 219 DPASAPGRGNYGPPVRRASEARMSSSSRDSESWDHSGGAGDSSRSPAGLRRANSVQASRP 278

Query: 155 PSSLRLLPPTPRPFPPAPAGGKGEGGG 181
                  P  P+P  P   GG   G G
Sbjct: 279 APGSVQSPAPPQPGQPGTPGGSRPGPG 305


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.134    0.418 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,984,723
Number of Sequences: 37866
Number of extensions: 1557860
Number of successful extensions: 13554
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 182
Number of HSP's successfully gapped in prelim test: 1320
Number of HSP's that attempted gapping in prelim test: 9195
Number of HSP's gapped (non-prelim): 4663
length of query: 400
length of database: 18,247,518
effective HSP length: 104
effective length of query: 296
effective length of database: 14,309,454
effective search space: 4235598384
effective search space used: 4235598384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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