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Search of human proteins with 239742631
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
sapiens]
(274 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239754138 PREDICTED: hypothetical protein [Homo sapiens] 567 e-162
gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo ... 567 e-162
gi|239748613 PREDICTED: hypothetical protein XP_002346732 [Homo ... 140 9e-34
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens] 59 6e-09
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 56 3e-08
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 56 3e-08
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 55 7e-08
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 55 7e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 54 1e-07
gi|18959210 WIRE protein [Homo sapiens] 54 1e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 54 1e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 54 1e-07
gi|18079216 CASK interacting protein 1 [Homo sapiens] 53 3e-07
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 53 3e-07
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 53 3e-07
gi|150170670 piccolo isoform 2 [Homo sapiens] 52 4e-07
gi|150378539 piccolo isoform 1 [Homo sapiens] 52 4e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 52 4e-07
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 51 1e-06
gi|150170729 microtubule associated serine/threonine kinase 3 [H... 51 1e-06
gi|40353727 synaptopodin isoform A [Homo sapiens] 50 2e-06
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 50 2e-06
gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens] 50 2e-06
gi|7706501 WW domain binding protein 11 [Homo sapiens] 50 2e-06
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens] 50 2e-06
gi|7662302 TBK1 binding protein 1 [Homo sapiens] 50 2e-06
gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo sapi... 50 2e-06
gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo sapi... 50 2e-06
gi|153792074 proline rich 12 [Homo sapiens] 50 2e-06
gi|6912458 calcineurin binding protein 1 [Homo sapiens] 50 3e-06
>gi|239754138 PREDICTED: hypothetical protein [Homo sapiens]
Length = 274
Score = 567 bits (1462), Expect = e-162
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD 60
MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD
Sbjct: 1 MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD 60
Query: 61 PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR
Sbjct: 61 PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
Query: 121 AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL 180
AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL
Sbjct: 121 AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL 180
Query: 181 RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG 240
RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG
Sbjct: 181 RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG 240
Query: 241 PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH 274
PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH
Sbjct: 241 PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH 274
>gi|239742631 PREDICTED: hypothetical protein XP_002342600 [Homo
sapiens]
Length = 274
Score = 567 bits (1462), Expect = e-162
Identities = 274/274 (100%), Positives = 274/274 (100%)
Query: 1 MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD 60
MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD
Sbjct: 1 MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD 60
Query: 61 PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR
Sbjct: 61 PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
Query: 121 AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL 180
AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL
Sbjct: 121 AGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRL 180
Query: 181 RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG 240
RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG
Sbjct: 181 RRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSPLILAWVPALSG 240
Query: 241 PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH 274
PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH
Sbjct: 241 PALNSGKWELQARSVRVWALMSLGMVAQGHRGGH 274
>gi|239748613 PREDICTED: hypothetical protein XP_002346732 [Homo
sapiens]
Length = 67
Score = 140 bits (354), Expect = 9e-34
Identities = 67/67 (100%), Positives = 67/67 (100%)
Query: 208 MRRGCRTLTARRPLDSGRGLSPLILAWVPALSGPALNSGKWELQARSVRVWALMSLGMVA 267
MRRGCRTLTARRPLDSGRGLSPLILAWVPALSGPALNSGKWELQARSVRVWALMSLGMVA
Sbjct: 1 MRRGCRTLTARRPLDSGRGLSPLILAWVPALSGPALNSGKWELQARSVRVWALMSLGMVA 60
Query: 268 QGHRGGH 274
QGHRGGH
Sbjct: 61 QGHRGGH 67
>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
Length = 538
Score = 58.5 bits (140), Expect = 6e-09
Identities = 54/191 (28%), Positives = 66/191 (34%), Gaps = 27/191 (14%)
Query: 19 WKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPA 78
+K S A QPP R P P PP R + A PP +P PPPPP P
Sbjct: 87 YKGSISYRNAARVQPPRRGATP-PAPPRAPRGAPAAAAAAAPPP-----TPAPPPPPAPV 140
Query: 79 -------APHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPA 131
AP A A P+ + R P+ P P A A PA
Sbjct: 141 AAAAPARAPRAAAAAATAPPSPGPAQPGPRAQRAAPLAAPPPAP------AAPPAVAPPA 194
Query: 132 SPRARAARAISNQSSPPPPPPSRARSRSLRLSAP--------GSRHDAEKASERNRLRRK 183
PR A++ + P PPPP + P G A A+ LR
Sbjct: 195 GPRRAPPPAVAAREPPLPPPPQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAARPVSLREV 254
Query: 184 KRLVLGRGGGG 194
R + G GG G
Sbjct: 255 VRYLGGSGGAG 265
Score = 48.1 bits (113), Expect = 8e-06
Identities = 46/156 (29%), Positives = 56/156 (35%), Gaps = 13/156 (8%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPP-------PPPPPAAPHVLGA 85
PP+ PP PP+ R +PP LP P+PP PPPP P G
Sbjct: 181 PPAPAAPPAVAPPAGPRRAPPPAVAAREPP--LPPPPQPPAPPQQQQPPPPQPQPPPEGG 238
Query: 86 RVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRAR---AARAIS 142
V AG R + V G G R +GR G AA R A A+
Sbjct: 239 AVRAGGAARPVSLREVVRYLGGSGGAGGRLTRGRVQGLLEEEAAARGRLERTRLGALALP 298
Query: 143 NQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERN 178
P PP+ A +R R G EK E +
Sbjct: 299 RGDRPGRAPPA-ASARPSRSKRGGEERVLEKEEEED 333
Score = 29.3 bits (64), Expect = 3.9
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 8/59 (13%)
Query: 101 RVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRA-RAARAISNQSSPPP---PPPSRA 155
RVS +G + + Q R GA PA PRA R A A + ++PPP PPP A
Sbjct: 84 RVSYKGSISYRNAARVQPPRRGA----TPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPA 138
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 56.2 bits (134), Expect = 3e-08
Identities = 57/174 (32%), Positives = 65/174 (37%), Gaps = 12/174 (6%)
Query: 66 PGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARM 125
PGSP PPPP PAA VLGA A G + A + + R G R AG
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVG--RKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
Query: 126 RSAA---PASPRARAARAISNQSSPPPPPPSRA--RSRSLRLSAPGSRHDAEKASERNR- 179
R+ A PAS R A N S P P RA +R L G R AE+ R +
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 180 LRRKKRLVLGRGG----GGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSP 229
KR L G G ARR R + RP S R P
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Score = 45.8 bits (107), Expect = 4e-05
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 54/261 (20%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPP---PPP-AAPHV 82
PA PS T PP PPS + P L++P PP + P SP PP PPP AAP +
Sbjct: 455 PASPPVSPSAT-PPSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 83 LGAR--------VAAGPTHRLSASHSRVSSRGPVGTK------------PKRPGQGRRAG 122
A+ +A P L + + + P P+ P
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 570
Query: 123 ARMRSAAPASPRARAAR------AISNQSSP-------PPPPPSRARSRSLRLSAPG-SR 168
++ + PASP +A R ++ S P P PPP +RS S LS P +
Sbjct: 571 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 630
Query: 169 HDAEKASERNRLRRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARR---PLDSGR 225
H + S LR G GG + + E A C R P + R
Sbjct: 631 HSSSATSTPEELRGYDS---GPEGGAAASPPPDAELA-----ACHPAAWSRGPAPPLAFR 682
Query: 226 GLSPLILAWVPALSGPALNSG 246
G L W PA +GP G
Sbjct: 683 GAPGAPLPWPPA-TGPGSADG 702
Score = 44.7 bits (104), Expect = 9e-05
Identities = 41/130 (31%), Positives = 58/130 (44%), Gaps = 9/130 (6%)
Query: 39 PPLPGPPSRSRSPSSRLKLPADPPRALPGSP--EPPPPPPPA-APHVLGARVAAGPTHRL 95
PP PP+ + P L+ P PP + P SP P P P A A H+L A + P+ +
Sbjct: 392 PPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448
Query: 96 SASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
A S +S PV P Q + A P SP A+ +S ++PPP P
Sbjct: 449 QAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVPPSP--PASPPMSPSATPPPQAPPPL 505
Query: 156 RSRSLRLSAP 165
+ L+L+ P
Sbjct: 506 AAPPLQLAKP 515
Score = 44.3 bits (103), Expect = 1e-04
Identities = 47/156 (30%), Positives = 62/156 (39%), Gaps = 29/156 (18%)
Query: 22 SSLIHPARSNQPPSRTCPPLPGPP-SRSRSPSSRLKLPADPPRALPGSPEPPP-----PP 75
S L P+ S S+ P LP P S S + LP PP SP PP P
Sbjct: 302 SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPP-----SPSAPPSLQTLPS 356
Query: 76 PPAAPHVLGARVAAGPTHRLSASHSRVSSR--GPVGTKPKR--------PGQGRRAG--- 122
PPA P PT L A+HS + S P+ T P + P Q +
Sbjct: 357 PPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 414
Query: 123 ---ARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
+ + + +P +P A A + SPPP PP +A
Sbjct: 415 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Score = 40.8 bits (94), Expect = 0.001
Identities = 43/170 (25%), Positives = 61/170 (35%), Gaps = 27/170 (15%)
Query: 7 PAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGP----------------PSRSRS 50
P+ + R S+ L PA P +R PP GP P+ R
Sbjct: 172 PSPAMARRSRAAGTEVGLPRPA----PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRR 227
Query: 51 PSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGT 110
PS+ L R+L S P P + P G T R A S+ +G
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARG-------TPRAPAHPSQPKPKGLQAL 280
Query: 111 KPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSL 160
+P + R+ A +SP A + + + QS PP P+ S SL
Sbjct: 281 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSL 330
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 17 EVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPP--- 73
E K S+L AR + P P RSR+ + + LP P A P P P
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 74 ----------PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGA 123
P PAA R +AG + AS S SS P+ + P R G R G
Sbjct: 209 VSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSSSATPL-SSPARSGPSAR-GT 262
Query: 124 RMRSAAPASPRARAARAISNQSSPPP 149
A P+ P+ + +A+ PP
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPP 288
Score = 37.0 bits (84), Expect = 0.019
Identities = 40/140 (28%), Positives = 50/140 (35%), Gaps = 12/140 (8%)
Query: 39 PPLPGPPSRSRSPSSRL--KLPADPPRALPGSPEPPP-----PPPPAAPHVLGA---RVA 88
PP P S S +P S+ L A P + P P PP PPP AP L A ++A
Sbjct: 454 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 513
Query: 89 AGPTHR--LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
P A+ + P + P + A M A P+A A
Sbjct: 514 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 573
Query: 147 PPPPPPSRARSRSLRLSAPG 166
PP PP S R PG
Sbjct: 574 PPSPPASPTLQAPRRPPTPG 593
Score = 35.4 bits (80), Expect = 0.054
Identities = 37/144 (25%), Positives = 51/144 (35%), Gaps = 16/144 (11%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPG------------S 68
P S + PP P L PPS SP+ L+ P PP P +
Sbjct: 551 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPT--LQAPRRPPTPGPDTSVSGPRLTLALA 608
Query: 69 PEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSA 128
P PPPPP + L AG H SA+ + RG A + +
Sbjct: 609 PGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 666
Query: 129 APASPRARAARAISNQSSPPPPPP 152
PA+ A ++ + +P P P
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLP 690
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/136 (24%), Positives = 50/136 (36%), Gaps = 24/136 (17%)
Query: 37 TCPPLPGPPS-----RSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGP 91
T P PG PS RSR+ + + LP P A P P P +
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS------------- 210
Query: 92 THRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP--P 149
SAS + P + G G + A ++ A+P + AR+ + P P
Sbjct: 211 ----SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 150 PPPSRARSRSLRLSAP 165
PS+ + + L+ P
Sbjct: 267 AHPSQPKPKGLQALRP 282
Score = 33.5 bits (75), Expect = 0.21
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 29/168 (17%)
Query: 30 SNQPPSRTCPPLPG-----PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPP-----AA 79
S P SR PP G PP+++ SP P P G+ P P A
Sbjct: 87 SRNPASR--PPASGRGERAPPAKNTSPG-----PVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPV-GT-KPKRPGQGRRAGARMRSAAPA------ 131
V + P ++ +R + GP GT P + R AG + PA
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 132 ----SPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKAS 175
PR + A + ++ P P R S L P SR + A+
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 56.2 bits (134), Expect = 3e-08
Identities = 57/174 (32%), Positives = 65/174 (37%), Gaps = 12/174 (6%)
Query: 66 PGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARM 125
PGSP PPPP PAA VLGA A G + A + + R G R AG
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVG--RKPLAERAGGIGGATIPESAPRAGPTRSAGTSS 87
Query: 126 RSAA---PASPRARAARAISNQSSPPPPPPSRA--RSRSLRLSAPGSRHDAEKASERNR- 179
R+ A PAS R A N S P P RA +R L G R AE+ R +
Sbjct: 88 RNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA 147
Query: 180 LRRKKRLVLGRGG----GGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSP 229
KR L G G ARR R + RP S R P
Sbjct: 148 TEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 201
Score = 54.7 bits (130), Expect = 9e-08
Identities = 51/163 (31%), Positives = 63/163 (38%), Gaps = 18/163 (11%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPP--PPA 78
PSS+ P PP+ PPL G PS SP + A P ALP PP PP PP
Sbjct: 584 PSSIATPP-PQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPL 642
Query: 79 AP--------------HVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGAR 124
+P H+L A + P+ + A S +S PV P Q + A
Sbjct: 643 SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSATPPSQAPPSLAA 701
Query: 125 MRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGS 167
P SP A + S P PPP A + S P S
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPAS 744
Score = 43.5 bits (101), Expect = 2e-04
Identities = 51/170 (30%), Positives = 60/170 (35%), Gaps = 33/170 (19%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPS---SRLKLP------ADPPRALPGSPEPPPP------ 74
S PPS PPL PPS SP S P A PP +P SP PP
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSAT 752
Query: 75 PPPAAPHVLGA-RVAAGPTHRLSASHSRVSSRGP-----VGTKPKR---------PGQ-- 117
PPP P +L A + P+ S S ++ P + T P + PGQ
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAP 812
Query: 118 -GRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPG 166
A M A P+A A PP PP S R PG
Sbjct: 813 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 862
Score = 41.6 bits (96), Expect = 8e-04
Identities = 43/162 (26%), Positives = 57/162 (35%), Gaps = 30/162 (18%)
Query: 22 SSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRA-LPGSPEP-----PPPP 75
SSL P+ P S T PPL PS + P P P P P P PP P
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575
Query: 76 ---------------PPAAPHVLGARVAAG----PTHRLSASHSRVS---SRGPVGTKPK 113
PP AP L + G P L+ + + P+ P
Sbjct: 576 LTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPS 635
Query: 114 RPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
P + + + +P +P A A + SPPP PP +A
Sbjct: 636 PPASPPL--SPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 675
Score = 41.6 bits (96), Expect = 8e-04
Identities = 66/240 (27%), Positives = 86/240 (35%), Gaps = 41/240 (17%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD-----PPRALPGSPEPPPPPPPAAPHVLG 84
S PP R P L PP + PS LP PP+A P PP P+ P
Sbjct: 750 SATPPPRVPPLLAAPPLQV-PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFP 808
Query: 85 ARVAAGPTHRLSASHSRVSSRGPVGT-KPKRPGQGRRAGARMRSAAPASPRARAAR---- 139
+ P+ L S P+ T P+ P ++ + PASP +A R
Sbjct: 809 GQAPFSPSASLPMS--------PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860
Query: 140 --AISNQSSP-------PPPPPSRARSRSLRLSAPG-SRHDAEKASERNRLRRKKRLVLG 189
++ S P P PPP +RS S LS P + H + S LR G
Sbjct: 861 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS---G 917
Query: 190 RGGGGECAHAHEWECARRMRRGCRTLTARR---PLDSGRGLSPLILAWVPALSGPALNSG 246
GG + + E A C R P + RG L W PA +GP G
Sbjct: 918 PEGGAAASPPPDAELA-----ACHPAAWSRGPAPPLAFRGAPGAPLPWPPA-TGPGSADG 971
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 17 EVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPP--- 73
E K S+L AR + P P RSR+ + + LP P A P P P
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 208
Query: 74 ----------PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGA 123
P PAA R +AG + AS S SS P+ + P R G R G
Sbjct: 209 VSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSSSATPL-SSPARSGPSAR-GT 262
Query: 124 RMRSAAPASPRARAARAISNQSSPPP 149
A P+ P+ + +A+ PP
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPP 288
Score = 36.6 bits (83), Expect = 0.024
Identities = 37/132 (28%), Positives = 49/132 (37%), Gaps = 12/132 (9%)
Query: 39 PPLPGPPSRSRSPSSRL--KLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLS 96
PP P S S +P S+ L A P + P P PP P A P A P ++
Sbjct: 679 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVP 738
Query: 97 ASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAP--ASPRARAARAISNQSSPPP-PPPS 153
S P T P R + +A P P A+ +S + PPP PP+
Sbjct: 739 PSPPASPPMSPSATPPPRV-------PPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPA 791
Query: 154 RARSRSLRLSAP 165
A L +P
Sbjct: 792 LATPPLQALPSP 803
Score = 34.7 bits (78), Expect = 0.092
Identities = 47/192 (24%), Positives = 67/192 (34%), Gaps = 42/192 (21%)
Query: 21 PSSLIHPARSNQPPSRTCPPLP---------------GPPSRSRSPSSRL--KLPADPPR 63
PS AR PP PLP PPS S PS + PA PP
Sbjct: 307 PSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPS 366
Query: 64 ALPGSPEPPPP---------PPPAAPHVLGARVAAGPTHRLSASHSRV----------SS 104
P S PP PP PH L + P L+ S + ++
Sbjct: 367 QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQAT 426
Query: 105 RGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLR-LS 163
+ P++ + +R S P SP +A ++ P PP + S ++ LS
Sbjct: 427 HSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSL-----PASPPLQTSLSPAVSPLS 481
Query: 164 APGSRHDAEKAS 175
+P + H + S
Sbjct: 482 SPLTIHPLQALS 493
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/136 (24%), Positives = 50/136 (36%), Gaps = 24/136 (17%)
Query: 37 TCPPLPGPPS-----RSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGP 91
T P PG PS RSR+ + + LP P A P P P +
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS------------- 210
Query: 92 THRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP--P 149
SAS + P + G G + A ++ A+P + AR+ + P P
Sbjct: 211 ----SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Query: 150 PPPSRARSRSLRLSAP 165
PS+ + + L+ P
Sbjct: 267 AHPSQPKPKGLQALRP 282
Score = 33.5 bits (75), Expect = 0.21
Identities = 42/168 (25%), Positives = 59/168 (35%), Gaps = 29/168 (17%)
Query: 30 SNQPPSRTCPPLPG-----PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPP-----AA 79
S P SR PP G PP+++ SP P P G+ P P A
Sbjct: 87 SRNPASR--PPASGRGERAPPAKNTSPG-----PVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPV-GT-KPKRPGQGRRAGARMRSAAPA------ 131
V + P ++ +R + GP GT P + R AG + PA
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 132 ----SPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKAS 175
PR + A + ++ P P R S L P SR + A+
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Score = 32.0 bits (71), Expect = 0.60
Identities = 32/122 (26%), Positives = 49/122 (40%), Gaps = 4/122 (3%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGAR 86
P + P P+P PP + +P LP PP A P PP P P + L +
Sbjct: 303 PLATPSPSGTKARPVP-PPDNAATPLPAT-LPPSPPLATPLPLAPPSPSAPPSLQTLPSP 360
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAA-RAISNQS 145
A P+ + S + + P + P Q + AP SP A ++ +A ++
Sbjct: 361 PATPPS-QAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Query: 146 SP 147
SP
Sbjct: 420 SP 421
Score = 31.6 bits (70), Expect = 0.78
Identities = 35/127 (27%), Positives = 47/127 (37%), Gaps = 14/127 (11%)
Query: 33 PPSRTCPPLPGP----PSRSRSPSSRLKLPADPP--RALPGSPEPPPPPPPAAPHVLGAR 86
PP + P GP P + SPS P PP A P PP PP A P L
Sbjct: 287 PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPL--- 343
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKR-PGQGRRAGARMRSAAPASPRARAARAISNQS 145
A P+ SA S + P T P + P + + P + ++++ S
Sbjct: 344 --APPSP--SAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPS 399
Query: 146 SPPPPPP 152
PP P
Sbjct: 400 LQAPPSP 406
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.1 bits (131), Expect = 7e-08
Identities = 52/167 (31%), Positives = 63/167 (37%), Gaps = 50/167 (29%)
Query: 27 PARSNQP-PSRTCPPLPG-------------PPSRSRSP-SSRLKLPADPPRALPGSPEP 71
P QP P T PP PG P S SP S+R LP P RAL P P
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266
Query: 72 PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPA 131
PPPP P + V P P KP P+
Sbjct: 267 PPPPVGNRPSIHREAVPPPP---------------PQNNKPP---------------VPS 296
Query: 132 SPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERN 178
+PR A S+Q+ PPPPPPSR L S+ G+ + + +RN
Sbjct: 297 TPRPSA----SSQAPPPPPPPSRPGPPPLPPSSSGN-DETPRLPQRN 338
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 26/119 (21%)
Query: 35 SRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHR 94
S + PPLP P P + P P R PG P PPPPP + + G T R
Sbjct: 342 SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN--------GSTSR 393
Query: 95 LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS 153
+ ++ SR V + R+G R P P +A A PPPPPPS
Sbjct: 394 ALPATPQLPSRSGVDSP--------RSGPR----PPLPPDRPSAGA------PPPPPPS 434
Score = 45.4 bits (106), Expect = 5e-05
Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 36/163 (22%)
Query: 30 SNQPP-----SRTC---PPLPGPPSRSRSPSSRLKLPADPPR----ALPGSPEP------ 71
SN+PP SR PP P PP +R R +P PP+ +P +P P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 72 ----PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRS 127
PPP P P + + T RL + +SS P P R G
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------- 355
Query: 128 AAPASPRAR---AARAISNQSSPPPPPPSRARSRSLRLSAPGS 167
P P R R +S P PPPP +R+ S + P +
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 55.1 bits (131), Expect = 7e-08
Identities = 52/167 (31%), Positives = 63/167 (37%), Gaps = 50/167 (29%)
Query: 27 PARSNQP-PSRTCPPLPG-------------PPSRSRSP-SSRLKLPADPPRALPGSPEP 71
P QP P T PP PG P S SP S+R LP P RAL P P
Sbjct: 207 PGGPRQPSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266
Query: 72 PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPA 131
PPPP P + V P P KP P+
Sbjct: 267 PPPPVGNRPSIHREAVPPPP---------------PQNNKPP---------------VPS 296
Query: 132 SPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERN 178
+PR A S+Q+ PPPPPPSR L S+ G+ + + +RN
Sbjct: 297 TPRPSA----SSQAPPPPPPPSRPGPPPLPPSSSGN-DETPRLPQRN 338
Score = 46.6 bits (109), Expect = 2e-05
Identities = 38/119 (31%), Positives = 48/119 (40%), Gaps = 26/119 (21%)
Query: 35 SRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHR 94
S + PPLP P P + P P R PG P PPPPP + + G T R
Sbjct: 342 SSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRN--------GSTSR 393
Query: 95 LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS 153
+ ++ SR V + R+G R P P +A A PPPPPPS
Sbjct: 394 ALPATPQLPSRSGVDSP--------RSGPR----PPLPPDRPSAGA------PPPPPPS 434
Score = 45.4 bits (106), Expect = 5e-05
Identities = 46/163 (28%), Positives = 61/163 (37%), Gaps = 36/163 (22%)
Query: 30 SNQPP-----SRTC---PPLPGPPSRSRSPSSRLKLPADPPR----ALPGSPEP------ 71
SN+PP SR PP P PP +R R +P PP+ +P +P P
Sbjct: 247 SNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQA 306
Query: 72 ----PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRS 127
PPP P P + + T RL + +SS P P R G
Sbjct: 307 PPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG----------- 355
Query: 128 AAPASPRAR---AARAISNQSSPPPPPPSRARSRSLRLSAPGS 167
P P R R +S P PPPP +R+ S + P +
Sbjct: 356 PLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPAT 398
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 54.3 bits (129), Expect = 1e-07
Identities = 44/134 (32%), Positives = 60/134 (44%), Gaps = 15/134 (11%)
Query: 39 PPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSAS 98
PP+P PP P L A+P + EPP PPPP P+ + A+ P L
Sbjct: 258 PPIP-PPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGV 316
Query: 99 HSRVSSRGPVGTKPKRPG---QGRRAGARMRSAAPASP-------RARAAR--AISNQSS 146
+S SS P PK P ++AGA+ A PA P + R R A + +
Sbjct: 317 NS--SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLN 374
Query: 147 PPPPPPSRARSRSL 160
PPP PP+R+ + L
Sbjct: 375 PPPAPPARSPTTEL 388
Score = 42.7 bits (99), Expect = 3e-04
Identities = 50/167 (29%), Positives = 59/167 (35%), Gaps = 33/167 (19%)
Query: 22 SSLIHPARSNQPPSRTC----PPLPGPPSRSRSP----SSRLKLP-ADPPRAL------- 65
+S H A PP PP P PP P SS +K P PP L
Sbjct: 155 TSEAHGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV 214
Query: 66 -----PGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQG-- 118
P +P PPPPPPP P L P + + + P+ P P
Sbjct: 215 VAPPVPCAPPPPPPPPPPTPPPL-------PPASVLSDKAVKPQLAPLHLPPIPPPLPLL 267
Query: 119 RRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAP 165
G A PASP A A + PPP PP + S L AP
Sbjct: 268 PPCGYPGLKAEPASP---AQDAQEPPAPPPPLPPYASCSPRASLPAP 311
Score = 35.8 bits (81), Expect = 0.041
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 3/31 (9%)
Query: 55 LKLPADPPRALPGSPEP---PPPPPPAAPHV 82
+ +P PP LP P P PPPPPP+AP V
Sbjct: 1 MPVPPPPPPPLPPPPPPLGAPPPPPPSAPPV 31
Score = 30.8 bits (68), Expect = 1.3
Identities = 32/109 (29%), Positives = 39/109 (35%), Gaps = 22/109 (20%)
Query: 22 SSLIHPARSNQPPSRTCPP-------LPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPP 74
SS P + PS PP LP PP+ S K P A G PPP
Sbjct: 319 SSETPPPLPPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPA 378
Query: 75 PPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGA 123
PP A PT LS+ S + T ++PG R G+
Sbjct: 379 PP-----------ARSPTTELSSK----SQQATAWTPTQQPGGQLRNGS 412
Score = 30.0 bits (66), Expect = 2.3
Identities = 28/83 (33%), Positives = 33/83 (39%), Gaps = 19/83 (22%)
Query: 69 PEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSA 128
P PPPPP P P LGA P S PV T RRA + RSA
Sbjct: 4 PPPPPPPLPPPPPPLGAPPPPPP------------SAPPVSTD---TSSLRRADPKGRSA 48
Query: 129 APA----SPRARAARAISNQSSP 147
A R R I+++S+P
Sbjct: 49 LLADIQQGTRLRKVTQINDRSAP 71
>gi|18959210 WIRE protein [Homo sapiens]
Length = 440
Score = 54.3 bits (129), Expect = 1e-07
Identities = 57/175 (32%), Positives = 64/175 (36%), Gaps = 25/175 (14%)
Query: 1 MNSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPAD 60
M+S APA R P +HP R P P P P + PS + P
Sbjct: 195 MHSSKAPA--YNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIRTGPSGQSLAPPP 252
Query: 61 PP-RALPGSPEPPPPP----PPAAP--HVLGARVAAGPTHRL------SASHSRVSSRGP 107
PP R PG P P P P P H R GP L SAS S +S+R P
Sbjct: 253 PPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPP 312
Query: 108 V--------GTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSR 154
G P P R GA R A P P R + PPPPPSR
Sbjct: 313 PPARDPPSRGAAPPPPPPVIRNGA--RDAPPPPPPYRMHGSEPPSRGKPPPPPSR 365
Score = 49.7 bits (117), Expect = 3e-06
Identities = 45/131 (34%), Positives = 48/131 (36%), Gaps = 31/131 (23%)
Query: 27 PARSNQPPSRTCPPLPG---PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVL 83
P R N +T P+ G PP S SPS P P R P PPPPPP +
Sbjct: 277 PQRHNSLHRKTPGPVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVIRN-- 334
Query: 84 GARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISN 143
GAR A P S SRG KP P S PA P
Sbjct: 335 GARDAPPPPPPYRMHGSEPPSRG----KPPPP----------PSRTPAGP---------- 370
Query: 144 QSSPPPPPPSR 154
PPPPPP R
Sbjct: 371 --PPPPPPPLR 379
Score = 48.1 bits (113), Expect = 8e-06
Identities = 43/144 (29%), Positives = 61/144 (42%), Gaps = 25/144 (17%)
Query: 33 PPSR--TCPPLPGPPSRSRSPSSRLK--LPADPPRALPGSPEPPPPPPPAAPHVLGARVA 88
PP R PP P P S++P+ + LP P + L E PP PPP P +
Sbjct: 181 PPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVKPPPSPVNIR 240
Query: 89 AGPTHRLSASHSRVSSRGPVG-----------TKPKRPGQ----GRRAGARMRSAAPASP 133
GP+ + S + R P G + P+ P + R+ +R AP P
Sbjct: 241 TGPSGQ-SLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPVRGLAPPPP 299
Query: 134 RARAARAISNQSSPPPP---PPSR 154
+ + +SN+ PPPP PPSR
Sbjct: 300 TSASPSLLSNR--PPPPARDPPSR 321
Score = 33.9 bits (76), Expect = 0.16
Identities = 50/191 (26%), Positives = 58/191 (30%), Gaps = 59/191 (30%)
Query: 41 LPGPPSRSRSPSSRLKLPADPPRALPGSPE------------------------------ 70
L G P+ + PSSR P P A G P+
Sbjct: 107 LAGKPAL-QIPSSRAAAPRPPVSAASGRPQDDTDSSRASLPELPRMQRPSLPDLSRPNTT 165
Query: 71 ----------PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
PPPPPP G R A PT L S+ + P PGQ
Sbjct: 166 SSTGMKHSSSAPPPPPP------GRRANAPPT-PLPMHSSKAPAYNREKPLPPTPGQRLH 218
Query: 121 AGARMRSAAPASPRAR-------AARAISNQSSPPPPPPSRARSRSLR-LSAPGSRHDAE 172
G R PA P + S QS PPPPP R S+P + E
Sbjct: 219 PG---REGPPAPPPVKPPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPE 275
Query: 173 KASERNRLRRK 183
N L RK
Sbjct: 276 LPQRHNSLHRK 286
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 53.9 bits (128), Expect = 1e-07
Identities = 56/171 (32%), Positives = 61/171 (35%), Gaps = 15/171 (8%)
Query: 66 PGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARM 125
PGSP PPPP PAA VLGA A G G +G P RAG
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVG-------RKPLAERAGGIG-GATIPESAPRAGPTR 81
Query: 126 RSAAPASPRARAARAISNQSSPPPPPPSRA--RSRSLRLSAPGSRHDAEKASERNR-LRR 182
S PAS R A N S P P RA +R L G R AE+ R +
Sbjct: 82 TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEA 141
Query: 183 KKRLVLGRGG----GGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSP 229
KR L G G ARR R + RP S R P
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPP 192
Score = 45.8 bits (107), Expect = 4e-05
Identities = 72/261 (27%), Positives = 96/261 (36%), Gaps = 54/261 (20%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPP---PPP-AAPHV 82
PA PS T PP PPS + P L++P PP + P SP PP PPP AAP +
Sbjct: 416 PASPPVSPSAT-PPSQAPPSLAAPP---LQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471
Query: 83 LGAR--------VAAGPTHRLSASHSRVSSRGPVGTK------------PKRPGQGRRAG 122
A+ +A P L + + + P P+ P
Sbjct: 472 QLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL 531
Query: 123 ARMRSAAPASPRARAAR------AISNQSSP-------PPPPPSRARSRSLRLSAPG-SR 168
++ + PASP +A R ++ S P P PPP +RS S LS P +
Sbjct: 532 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAG 591
Query: 169 HDAEKASERNRLRRKKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARR---PLDSGR 225
H + S LR G GG + + E A C R P + R
Sbjct: 592 HSSSATSTPEELRGYDS---GPEGGAAASPPPDAELA-----ACHPAAWSRGPAPPLAFR 643
Query: 226 GLSPLILAWVPALSGPALNSG 246
G L W PA +GP G
Sbjct: 644 GAPGAPLPWPPA-TGPGSADG 663
Score = 45.1 bits (105), Expect = 7e-05
Identities = 47/160 (29%), Positives = 64/160 (40%), Gaps = 36/160 (22%)
Query: 27 PARSNQPPSRTC----PPLPGPPSRSRSP------SSRLKLPADPPRALPGSPEPPP--- 73
PA +QP + PP PP + +P SS L A P + P SP PP
Sbjct: 257 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL---ATPSPSAPPSPSAPPSLQ 313
Query: 74 --PPPPAAPHVLGARVAAGPTHRLSASHSRVSSR--GPVGTKPKR--------PGQGRRA 121
P PPA P PT L A+HS + S P+ T P + P Q +
Sbjct: 314 TLPSPPATPPSQATTSLGSPT--LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPS 371
Query: 122 G------ARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
+ + + +P +P A A + SPPP PP +A
Sbjct: 372 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 411
Score = 44.7 bits (104), Expect = 9e-05
Identities = 41/130 (31%), Positives = 58/130 (44%), Gaps = 9/130 (6%)
Query: 39 PPLPGPPSRSRSPSSRLKLPADPPRALPGSP--EPPPPPPPA-APHVLGARVAAGPTHRL 95
PP PP+ + P L+ P PP + P SP P P P A A H+L A + P+ +
Sbjct: 353 PPPQAPPALALPP---LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 409
Query: 96 SASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
A S +S PV P Q + A P SP A+ +S ++PPP P
Sbjct: 410 QAPFSPPAS-PPVSPSATPPSQAPPSLAAPPLQVPPSP--PASPPMSPSATPPPQAPPPL 466
Query: 156 RSRSLRLSAP 165
+ L+L+ P
Sbjct: 467 AAPPLQLAKP 476
Score = 40.0 bits (92), Expect = 0.002
Identities = 42/146 (28%), Positives = 56/146 (38%), Gaps = 19/146 (13%)
Query: 17 EVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPP--- 73
E K S+L AR + P P RSR+ + + LP P A P P P
Sbjct: 140 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 74 ----------PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGA 123
P PAA R +AG + AS S SS P+ + P R G R G
Sbjct: 200 VSSASEHSTTEPSPAARR----RPSAGGGLQRPASRSLSSSATPL-SSPARSGPSAR-GT 253
Query: 124 RMRSAAPASPRARAARAISNQSSPPP 149
A P+ P+ + +A+ PP
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPP 279
Score = 37.0 bits (84), Expect = 0.019
Identities = 40/140 (28%), Positives = 50/140 (35%), Gaps = 12/140 (8%)
Query: 39 PPLPGPPSRSRSPSSRL--KLPADPPRALPGSPEPPP-----PPPPAAPHVLGA---RVA 88
PP P S S +P S+ L A P + P P PP PPP AP L A ++A
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLA 474
Query: 89 AGPTHR--LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
P A+ + P + P + A M A P+A A
Sbjct: 475 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQV 534
Query: 147 PPPPPPSRARSRSLRLSAPG 166
PP PP S R PG
Sbjct: 535 PPSPPASPTLQAPRRPPTPG 554
Score = 35.4 bits (80), Expect = 0.054
Identities = 37/144 (25%), Positives = 51/144 (35%), Gaps = 16/144 (11%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPG------------S 68
P S + PP P L PPS SP+ L+ P PP P +
Sbjct: 512 PMSPLATPPPQAPPVLAAPLLQVPPSPPASPT--LQAPRRPPTPGPDTSVSGPRLTLALA 569
Query: 69 PEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSA 128
P PPPPP + L AG H SA+ + RG A + +
Sbjct: 570 PGPPPPPSRSPSSTLSGPDLAG--HSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 627
Query: 129 APASPRARAARAISNQSSPPPPPP 152
PA+ A ++ + +P P P
Sbjct: 628 HPAAWSRGPAPPLAFRGAPGAPLP 651
Score = 33.9 bits (76), Expect = 0.16
Identities = 33/136 (24%), Positives = 50/136 (36%), Gaps = 24/136 (17%)
Query: 37 TCPPLPGPPS-----RSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGP 91
T P PG PS RSR+ + + LP P A P P P +
Sbjct: 155 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS------------- 201
Query: 92 THRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP--P 149
SAS + P + G G + A ++ A+P + AR+ + P P
Sbjct: 202 ----SASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 257
Query: 150 PPPSRARSRSLRLSAP 165
PS+ + + L+ P
Sbjct: 258 AHPSQPKPKGLQALRP 273
Score = 33.1 bits (74), Expect = 0.27
Identities = 41/165 (24%), Positives = 59/165 (35%), Gaps = 28/165 (16%)
Query: 34 PSRTC-PPLPG-----PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPP-----AAPHV 82
P+RT PP G PP+++ SP P P G+ P P A V
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPG-----PVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 83 LGARVAAGPTHRLSASHSRVSSRGPV-GT-KPKRPGQGRRAGARMRSAAPA--------- 131
+ P ++ +R + GP GT P + R AG + PA
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193
Query: 132 -SPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKAS 175
PR + A + ++ P P R S L P SR + A+
Sbjct: 194 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 53.9 bits (128), Expect = 1e-07
Identities = 44/163 (26%), Positives = 53/163 (32%), Gaps = 34/163 (20%)
Query: 33 PPSRTCPPLPGPPSR----SRSPSSRLKLPADPPRALPGSPEPPPPP---------PPAA 79
PP PP P PP S SP L P PP + P P PPPPP PP
Sbjct: 402 PPPPLTPPAPSPPPPLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVV 461
Query: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPR----- 134
P + P + + GP GT P P G + +P+
Sbjct: 462 PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVAPKSTTFL 521
Query: 135 ------------ARAARAISN----QSSPPPPPPSRARSRSLR 161
AR++R I PP PP S LR
Sbjct: 522 KNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLR 564
Score = 44.7 bits (104), Expect = 9e-05
Identities = 49/159 (30%), Positives = 63/159 (39%), Gaps = 25/159 (15%)
Query: 14 HSKEVWKPSSLIH-PARSNQPPSRTCPPL------PGPPSRSRSPSSRLKLPADPPRALP 66
H + + +++H PA S++PP PPL PG P R SP L DPP
Sbjct: 1794 HLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER-HSPIQNL----DPPL--- 1845
Query: 67 GSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMR 126
P+ PPPA GAR+ P + S S GP+ P G +
Sbjct: 1846 -RPDSGSAPPPAPRSFSGARIKV-PNYSPSRRPLGGVSFGPL------PSPGSPSSLTHH 1897
Query: 127 SAAPASPRARAARAISNQSSP--PPPPPSRARSRSLRLS 163
P A S + SP P PPPSR S L+ S
Sbjct: 1898 IPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTS 1936
Score = 43.1 bits (100), Expect = 3e-04
Identities = 40/145 (27%), Positives = 50/145 (34%), Gaps = 25/145 (17%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSR---LKLP----------------ADPPRALPGSPEPPP 73
PP+ PP P PP + S R L+ P PP P +PEP P
Sbjct: 622 PPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPPLGAPEAPEPEP 681
Query: 74 PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASP 133
PP +P R A G T+ LS PV + G + A P
Sbjct: 682 PPADDSPAEPEPR-AVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQP 740
Query: 134 RARAARAISNQSSPPP-----PPPS 153
+ Q+ PPP PPPS
Sbjct: 741 LQALQTQLLPQALPPPQPQLQPPPS 765
Score = 39.3 bits (90), Expect = 0.004
Identities = 39/163 (23%), Positives = 53/163 (32%), Gaps = 32/163 (19%)
Query: 22 SSLIHPARSNQPPSRTCP-PLPGPPSRSRSPSSRLKLP------------------ADPP 62
S ++ P + PP P P+P PP PS+ + LP + P
Sbjct: 560 SPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELP 619
Query: 63 RALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAG 122
P P PP P PP AP R + + S + + V T P
Sbjct: 620 PPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLTPPP--------- 670
Query: 123 ARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAP 165
AP +P A + + P P R SL AP
Sbjct: 671 ----LGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAP 709
Score = 36.6 bits (83), Expect = 0.024
Identities = 36/116 (31%), Positives = 44/116 (37%), Gaps = 29/116 (25%)
Query: 56 KLPADPPRALPGSPEPPP--PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPK 113
KLP PP P +P PPP PPP + P L S P+ + P
Sbjct: 400 KLP--PPPLTPPAPSPPPPLPPP-----------STSPPPPLCPPPPPPVSPPPLPSPPP 446
Query: 114 RPGQGRR----------AGARMRSAAPASPRAR----AARAISNQSSPPPPPPSRA 155
P Q + +R R P +P R AARA +SPP P PS A
Sbjct: 447 PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTA 502
Score = 36.2 bits (82), Expect = 0.032
Identities = 49/190 (25%), Positives = 67/190 (35%), Gaps = 26/190 (13%)
Query: 14 HSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPP 73
HS E PSSL RS + + P R R + P PPR +P PP
Sbjct: 127 HSDEDVAPSSLRSALRSQRGRA--------PRGRGRKHKTT---PLPPPRLADVAPTPPK 175
Query: 74 PPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGR-----RAGARMRSA 128
P R+ T L + + + R +P P + R R R
Sbjct: 176 TPARKRGEEGTERMVQALTELLRRAQAPQAPRSR-ACEPSTPRRSRGRPPGRPAGPCRRK 234
Query: 129 APASPRARAARAISNQSSPPPPPPSRARSRSLRLS-----APGSRHDAEKASERNRLRRK 183
A A AA I PPP P + ++ S + PG+ ++S R R
Sbjct: 235 QQAVVVAEAAVTIPKPEPPPPVVPVKHQTGSWKCKEGPGPGPGTPRRGGQSSRGGRGGRG 294
Query: 184 KRLVLGRGGG 193
+ GRGGG
Sbjct: 295 R----GRGGG 300
Score = 35.8 bits (81), Expect = 0.041
Identities = 42/157 (26%), Positives = 53/157 (33%), Gaps = 26/157 (16%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADP-----PRALPGSPEPPPPPPPAAPHVLGARV 87
PP PPLP P+ S + + LP P P P PPPPPPP VL +
Sbjct: 2212 PPPVKQPPLP--PTISPTAPTSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLT-LVLSSGP 2268
Query: 88 AAGPTHRLSASH-SRVSSRGPVGTKPKR-----------------PGQGRRAGARMRSAA 129
A+ P + S S R P P + PG G +R+R
Sbjct: 2269 ASPPRQAIRVKRVSTFSGRSPPAPPPYKAPRLDEDGEASEDTPQVPGLGSGGFSRVRMKT 2328
Query: 130 PASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPG 166
P + P P + RS L L G
Sbjct: 2329 PTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDG 2365
Score = 34.3 bits (77), Expect = 0.12
Identities = 49/168 (29%), Positives = 62/168 (36%), Gaps = 46/168 (27%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKL-PADPPRA---LPGS---------PEPPPPPPPAA 79
P + PP P P + PS L PADP R LPG+ P P PP P +
Sbjct: 2131 PREESLPPAP-PLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATS 2189
Query: 80 PHVLGARVA------AG---------------PTHRLSASHSRVSSRGP-------VGTK 111
+L ++ AG PT +A S GP VG
Sbjct: 2190 KIILVNKLGQVFVKMAGEGEPVPPPVKQPPLPPTISPTAPTSWTLPPGPLLGVLPVVGVV 2249
Query: 112 PKRPGQGRRAGARMRSAAPASPRARAARA--ISNQS--SPPPPPPSRA 155
P + S+ PASP +A R +S S SPP PPP +A
Sbjct: 2250 RPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKA 2297
Score = 33.1 bits (74), Expect = 0.27
Identities = 35/133 (26%), Positives = 50/133 (37%), Gaps = 9/133 (6%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALP-GSPEPPPPPPPAAPHVLGA 85
P ++ PP R PP+ +R+K+P P P G P P P +P L
Sbjct: 1837 PIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTH 1896
Query: 86 RVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSA-----APASPRARAARA 140
+ A R SR P P RP R A ++++ P + A
Sbjct: 1897 HIPTVGDPDFPAPPRR--SRRPSPLAP-RPPPSRWASPPLKTSPQLRVPPPTSVVTALTP 1953
Query: 141 ISNQSSPPPPPPS 153
S + +PP P PS
Sbjct: 1954 TSGELAPPGPAPS 1966
Score = 33.1 bits (74), Expect = 0.27
Identities = 25/61 (40%), Positives = 27/61 (44%), Gaps = 12/61 (19%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLP-----ADPPRALPGSPEPPPPP 75
PSSL H P+ P P PP RSR PS P A PP L SP+ PP
Sbjct: 1891 PSSLTHHI-----PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPP--LKTSPQLRVPP 1943
Query: 76 P 76
P
Sbjct: 1944 P 1944
Score = 33.1 bits (74), Expect = 0.27
Identities = 26/85 (30%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 6 APAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRAL 65
AP + +R S +P P+R PP +T P L PP S + P A
Sbjct: 1908 APPRRSRRPSPLAPRPP----PSRWASPPLKTSPQLRVPPPTSVVTALT---PTSGELAP 1960
Query: 66 PGSPEPPPPPPPAAPHVLGARVAAG 90
PG PPPP P V +G
Sbjct: 1961 PGPAPSPPPPEDLGPDFEDMEVVSG 1985
Score = 32.7 bits (73), Expect = 0.35
Identities = 34/124 (27%), Positives = 38/124 (30%), Gaps = 25/124 (20%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101
P PP SP R + PP +P P PP P P
Sbjct: 552 PKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPST------------------- 592
Query: 102 VSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLR 161
PV KR R R S P A SPPP P + +R R L
Sbjct: 593 -----PVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSR-RPLL 646
Query: 162 LSAP 165
L AP
Sbjct: 647 LRAP 650
Score = 30.0 bits (66), Expect = 2.3
Identities = 26/83 (31%), Positives = 29/83 (34%), Gaps = 11/83 (13%)
Query: 11 LKRHSKEVWKPSSLIHPARSNQP--------PSR-TCPPLPGPPSRSRSPSSRLKLPADP 61
L H V P P RS +P PSR PPL P P + + P
Sbjct: 1894 LTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTP 1953
Query: 62 PRALPGSPEPPPPPPPAAPHVLG 84
P P P PPP P LG
Sbjct: 1954 TSGELAPPGPAPSPPP--PEDLG 1974
>gi|18079216 CASK interacting protein 1 [Homo sapiens]
Length = 1431
Score = 53.1 bits (126), Expect = 3e-07
Identities = 57/191 (29%), Positives = 69/191 (36%), Gaps = 53/191 (27%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTC---PPLPGPPSRSRSPSSRLKLPADPPRAL--- 65
+R + E P L P +PP PPLP P +R P+ K P P L
Sbjct: 1179 RRPASEQAGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPA---KPPVSPKPVLTQP 1235
Query: 66 -------------------PGSPE------------PPPPPPPAAPHVLGARVAAGPTHR 94
PGSPE P PPPPP AP + A VA P+
Sbjct: 1236 VPKLQGSPTPTSKKVPLPGPGSPEVKRAHGTPPPVSPKPPPPPTAPKPVKA-VAGLPSGS 1294
Query: 95 LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRA----------RAARAISNQ 144
S + +R P K PG GA A P SP A RAA A +
Sbjct: 1295 AGPSPAPSPARQPPAALAKPPGTPPSLGA--SPAKPPSPGAPALHVPAKPPRAAAAAAAA 1352
Query: 145 SSPPPPPPSRA 155
++ PP PP A
Sbjct: 1353 AAAPPAPPEGA 1363
Score = 46.2 bits (108), Expect = 3e-05
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 10/134 (7%)
Query: 29 RSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVA 88
R + R P P PP S + + P G PE PPPPPPA P +A
Sbjct: 1150 RRPKAKEREAGPEP-PPPLSVYHNGTGTVRRRPASEQAGPPELPPPPPPAEPP--PTDLA 1206
Query: 89 AGPTHRLSASHSRVSSRGPVGTK-------PKRPGQGRRAGARMRSAAPASPRARAARAI 141
P +R ++ PV K PK G ++ P SP + A
Sbjct: 1207 HLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTPTSKKVPLPGPGSPEVKRAHGT 1266
Query: 142 SNQSSPPPPPPSRA 155
SP PPPP A
Sbjct: 1267 PPPVSPKPPPPPTA 1280
Score = 42.4 bits (98), Expect = 4e-04
Identities = 37/137 (27%), Positives = 53/137 (38%), Gaps = 7/137 (5%)
Query: 34 PSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTH 93
PS + P P P + P++ K P PP +L SP PP P A H V A P
Sbjct: 1291 PSGSAGPSPAPSPARQPPAALAKPPGTPP-SLGASPAKPPSPGAPALH-----VPAKPP- 1343
Query: 94 RLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS 153
R +A+ + ++ P + PG R SA A+ I + + P +
Sbjct: 1344 RAAAAAAAAAAAPPAPPEGASPGDSARQKLEETSACLAAALQAVEEKIRQEDAQGPRDSA 1403
Query: 154 RARSRSLRLSAPGSRHD 170
+S L GS D
Sbjct: 1404 AEKSTGSILDDIGSMFD 1420
Score = 39.7 bits (91), Expect = 0.003
Identities = 42/161 (26%), Positives = 59/161 (36%), Gaps = 9/161 (5%)
Query: 21 PSSLIHPARSNQPPSR-TCPPLPGPPSRSRSP-SSRLKLPADPPRALPGSPEP---PPPP 75
P P R R + PP+PG P + P +S P P + PGSP+ P P
Sbjct: 738 PPREARPGRHGHSIKRASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGSPQALGGPHGP 797
Query: 76 PPAAPHVLGARVAAGPTHRLSASHSRVSS---RGPVGTKPKRPGQGRRAGARMRSAAPAS 132
PA V PT R + S S RG P +P +G A A P
Sbjct: 798 APATAKVKPTPQLLPPTERPMSPRSLPQSPTHRGFAYVLP-QPVEGEVGPAAPGPAPPPV 856
Query: 133 PRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEK 173
P A + ++ P P + R +A S + ++
Sbjct: 857 PTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDE 897
Score = 38.5 bits (88), Expect = 0.006
Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 13/71 (18%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSS-------RLKLPADPPRALPGSPE--- 70
PS PAR QPP+ P PPS SP+ L +PA PPRA +
Sbjct: 1297 PSPAPSPAR--QPPAALAKPPGTPPSLGASPAKPPSPGAPALHVPAKPPRAAAAAAAAAA 1354
Query: 71 -PPPPPPPAAP 80
PP PP A+P
Sbjct: 1355 APPAPPEGASP 1365
Score = 38.1 bits (87), Expect = 0.008
Identities = 44/167 (26%), Positives = 64/167 (38%), Gaps = 46/167 (27%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADP---------PRAL-----PGSPEPP 72
PA + P+ P L P R SP S LP P P+ + P +P P
Sbjct: 799 PATAKVKPT---PQLLPPTERPMSPRS---LPQSPTHRGFAYVLPQPVEGEVGPAAPGPA 852
Query: 73 PPPPPAAPHVL-----------GARVAAGPTHRLSASHSRV--------SSRGPVGTKPK 113
PPP P A L + A +R +AS S ++ GP T +
Sbjct: 853 PPPVPTAVPTLCLPPEADAEPGRPKKRAHSLNRYAASDSEPERDELLVPAAAGPYATVQR 912
Query: 114 RPGQGRRAGARMRSAAPASPRARAARAIS---NQSSPPPPPPSRARS 157
R G+ +R+ A A +++ + + PPPPPP R+ S
Sbjct: 913 RVGRSHS----VRAPAGADKNVNRSQSFAVRPRKKGPPPPPPKRSSS 955
Score = 31.6 bits (70), Expect = 0.78
Identities = 39/154 (25%), Positives = 54/154 (35%), Gaps = 33/154 (21%)
Query: 39 PPLPGP-PSRSRSP----------SSRLKLPADPPRALPGSPEPP----PPPPPAAPHV- 82
PP P P P+ +SP S L+ P + + E P PP P A
Sbjct: 634 PPPPEPTPADCQSPKMTTFQDSELSDELQAAMTGPAEVGPTTEKPSSHLPPTPRATTRQD 693
Query: 83 --LGARVA-------------AGPTHRLSASHSRVSSRGPV-GTKPKRPGQGRRAGARMR 126
LG R GP+ +S S + GP GT P+ GR + R
Sbjct: 694 SSLGGRARHMSSSQELLGDGPPGPSSPMSRSQEYLLDEGPAPGTPPREARPGRHGHSIKR 753
Query: 127 SAAPASP-RARAARAISNQSSPPPPPPSRARSRS 159
++ P P + R PP P++ R S
Sbjct: 754 ASVPPVPGKPRQVLPPGTSHFTPPQTPTKTRPGS 787
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/256 (23%), Positives = 102/256 (39%), Gaps = 29/256 (11%)
Query: 6 APAKFLKRHSKEVWKPSSLIHPARSNQ--PPSRTCPPLPGPPSRSRSPSSRLKL------ 57
APA L H +E K S+L PA + P S+ PG S+ + SR++
Sbjct: 825 APASGLP-HKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSE 883
Query: 58 -PADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSA---------SHSRVSSRGP 107
P L PPPPP A+ G + + P+ + + S V +
Sbjct: 884 SPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNS 943
Query: 108 VGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS-RARSRSLRLSAPG 166
KP +PG+G + + PA+P+ ++A+ SP P P + + S +L P
Sbjct: 944 DAAKPSQPGEGLK-----KPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPS 998
Query: 167 SRHDAEKASERNRLRRKK----RLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLD 222
S S R LR+ + R+ G G + E C R + + L+
Sbjct: 999 STAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLE 1058
Query: 223 SGRGLSPLILAWVPAL 238
+G+ L +++V ++
Sbjct: 1059 AGKNLYTFCVSYVDSI 1074
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 53.1 bits (126), Expect = 3e-07
Identities = 61/256 (23%), Positives = 102/256 (39%), Gaps = 29/256 (11%)
Query: 6 APAKFLKRHSKEVWKPSSLIHPARSNQ--PPSRTCPPLPGPPSRSRSPSSRLKL------ 57
APA L H +E K S+L PA + P S+ PG S+ + SR++
Sbjct: 844 APASGLP-HKEEAGKGSALGTPAAAEPVTPTSKAGSGAPGGTSKGPAEESRVRRHKHSSE 902
Query: 58 -PADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSA---------SHSRVSSRGP 107
P L PPPPP A+ G + + P+ + + S V +
Sbjct: 903 SPGRDKGKLSRLKPAPPPPPAASAGKAGGKPSQSPSQEAAGEAVLGAKTKATSLVDAVNS 962
Query: 108 VGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS-RARSRSLRLSAPG 166
KP +PG+G + + PA+P+ ++A+ SP P P + + S +L P
Sbjct: 963 DAAKPSQPGEGLK-----KPVLPATPKPQSAKPSGTPISPAPVPSTLPSASSALAGDQPS 1017
Query: 167 SRHDAEKASERNRLRRKK----RLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLD 222
S S R LR+ + R+ G G + E C R + + L+
Sbjct: 1018 STAFIPLISTRVSLRKTRQPPERIASGAITKGVVLDSTEALCLAISRNSEQMASHSAVLE 1077
Query: 223 SGRGLSPLILAWVPAL 238
+G+ L +++V ++
Sbjct: 1078 AGKNLYTFCVSYVDSI 1093
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 52.4 bits (124), Expect = 4e-07
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 34 PSRTCPPLPGP---PSRSRSP---SSRLKLPADPPRALPGSPEPPPPPP-PAAPHVLGAR 86
P++T PGP P++ P S++ P PP LPG +PPP P PA P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
A P+ + ++ GP P++PG + + SA P++ + A+ + QS+
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 147 PP 148
P
Sbjct: 556 KP 557
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 20 KPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAA 79
KP+S + S P + P P P RS S + P PP P P PPPPPPP
Sbjct: 2371 KPASQLP---SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPV 108
P + P +L+ + S V++ P+
Sbjct: 2428 PPPTSPKPTILPKKKLTVA-SPVTTATPL 2455
Score = 42.7 bits (99), Expect = 3e-04
Identities = 40/188 (21%), Positives = 70/188 (37%), Gaps = 5/188 (2%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPA-DPPRALPGSPE 70
++ S E P +L P + P++ P P + +P + P P PG P
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG-PT 437
Query: 71 PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSR--GPVGTKPKRPGQGRRAGARMRSA 128
P P + + G T ++ S+ GP P++PG + + SA
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 129 APASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGS-RHDAEKASERNRLRRKKRLV 187
P S + + + Q P P P + S PGS + A++ S ++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 188 LGRGGGGE 195
+ + G G+
Sbjct: 558 VSQTGSGK 565
Score = 34.7 bits (78), Expect = 0.092
Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 18/136 (13%)
Query: 16 KEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPP 75
KE KP +I P QPP P+P R P L+ P PE
Sbjct: 198 KEQGKPEGIIKPPLQQQPPK----PIPKQQGPGRDP---LQQDGTPKSISSQQPEKIKSQ 250
Query: 76 PPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRA 135
PP + GPT H+++ P+ RP + R S P+ P
Sbjct: 251 PPGT-----GKPIQGPTQTPQTDHAKL----PLQRDASRPQTKQADIVRGESVKPSLP-- 299
Query: 136 RAARAISNQSSPPPPP 151
++ Q +P PP
Sbjct: 300 SPSKPPIQQPTPGKPP 315
Score = 32.0 bits (71), Expect = 0.60
Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 20/167 (11%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAA 89
S P + PPL P+ SPS++ K PP A +P PP P+ P A
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAK---QPPEA-DSLSKPAPPKEPSVPSEQDKAPVA 750
Query: 90 G---PTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
++ + + S TKP P ++ A ++ +P + A +QS
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT----TPPLKTDSAKPSQSF 806
Query: 147 PP-----PPPPSRA----RSRSLRLSAPGSRHDAEKASERNRLRRKK 184
PP P S+A S S +S PG +++ + + +++K+
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Score = 31.2 bits (69), Expect = 1.0
Identities = 45/181 (24%), Positives = 56/181 (30%), Gaps = 55/181 (30%)
Query: 42 PGPPSRSRSPSSRLKLPAD------PPRALPGSPEPP-----PPPPPA------------ 78
PGP PS K A PP PG+ +PP P PPA
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 79 -APHVLGARVAAG------------PTHRLSAS---------HSRVSSRGPVGTKPKRPG 116
P L G PT ++ S + GP T ++PG
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 117 QGR----RAGARMRSA------APASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPG 166
G+ +AG SA P S A+ Q P PPP + S PG
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 167 S 167
S
Sbjct: 506 S 506
Score = 30.8 bits (68), Expect = 1.3
Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLP---ADPPRALPGSPEPPPPPPPAAPHVLGAR 86
S QP +T P SP + P A P + L +PEP PPP L
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPG-QGRRAGARMRSAAPASPR----ARAARAI 141
+A A +S P PK P + A + P P+ +
Sbjct: 716 PSAKAKQPPEA--DSLSKPAP----PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769
Query: 142 SNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASE 176
S+ ++ P P S+ +S++ + P + D+ K S+
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Score = 30.0 bits (66), Expect = 2.3
Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 25/180 (13%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPS------RTCPP---LPGPPSRSRSPSSRLKLPADPP 62
K +K KP + P S PP +T P P P +SR S L D P
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 63 RALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAG 122
++ P +P+ V G G + S + + +S+ G G P G
Sbjct: 917 KSQPTTPQET---------VTGKLFGFGAS-IFSQASNLISTAGQPG-----PHSQSGPG 961
Query: 123 ARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRR 182
A M+ APA + ++ + PP P+++ AP + KA + ++R
Sbjct: 962 APMKQ-APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Score = 30.0 bits (66), Expect = 2.3
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 113 KRPGQGRRAGARMRSAAPASPRA---RAARAISNQSSPPPPPP 152
++P +G+ S+ PA PR ++ IS Q PPPPPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP 2412
Score = 29.3 bits (64), Expect = 3.9
Identities = 19/62 (30%), Positives = 23/62 (37%), Gaps = 22/62 (35%)
Query: 19 WKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPA 78
++ SSL A+ PP PP P PP P PPP PPP
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPP----------------------PPPPPPLPPPT 2431
Query: 79 AP 80
+P
Sbjct: 2432 SP 2433
Score = 28.1 bits (61), Expect = 8.6
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 44 PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGAR 86
PP+ + SPS K D S PP P PA P + +R
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSR 114
Score = 28.1 bits (61), Expect = 8.6
Identities = 32/140 (22%), Positives = 49/140 (35%), Gaps = 12/140 (8%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPG----SPEPPPPPPPAAPHVLGARVAAGPTHRLSA 97
P PS S+ P + P PP PG P P PPA P L +A P
Sbjct: 296 PSLPSPSKPPIQQ-PTPGKPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 98 SHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARA-----ARAISNQSSPPPPPP 152
+++ P ++ G+ S+ P+A A + + Q P PP
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 153 SRARSRSLRLSAPGSRHDAE 172
+ + PG + A+
Sbjct: 413 QQVGTPKPLAQQPGLQSPAK 432
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 52.4 bits (124), Expect = 4e-07
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 7/122 (5%)
Query: 34 PSRTCPPLPGP---PSRSRSP---SSRLKLPADPPRALPGSPEPPPPPP-PAAPHVLGAR 86
P++T PGP P++ P S++ P PP LPG +PPP P PA P
Sbjct: 436 PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPG 495
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
A P+ + ++ GP P++PG + + SA P++ + A+ + QS+
Sbjct: 496 SAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 147 PP 148
P
Sbjct: 556 KP 557
Score = 43.5 bits (101), Expect = 2e-04
Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 4/89 (4%)
Query: 20 KPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAA 79
KP+S + S P + P P P RS S + P PP P P PPPPPPP
Sbjct: 2371 KPASQLP---SGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 80 PHVLGARVAAGPTHRLSASHSRVSSRGPV 108
P + P +L+ + S V++ P+
Sbjct: 2428 PPPTSPKPTILPKKKLTVA-SPVTTATPL 2455
Score = 42.7 bits (99), Expect = 3e-04
Identities = 40/188 (21%), Positives = 70/188 (37%), Gaps = 5/188 (2%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPA-DPPRALPGSPE 70
++ S E P +L P + P++ P P + +P + P P PG P
Sbjct: 379 EKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPG-PT 437
Query: 71 PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSR--GPVGTKPKRPGQGRRAGARMRSA 128
P P + + G T ++ S+ GP P++PG + + SA
Sbjct: 438 KTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSA 497
Query: 129 APASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGS-RHDAEKASERNRLRRKKRLV 187
P S + + + Q P P P + S PGS + A++ S ++
Sbjct: 498 KPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKP 557
Query: 188 LGRGGGGE 195
+ + G G+
Sbjct: 558 VSQTGSGK 565
Score = 34.7 bits (78), Expect = 0.092
Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 18/136 (13%)
Query: 16 KEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPP 75
KE KP +I P QPP P+P R P L+ P PE
Sbjct: 198 KEQGKPEGIIKPPLQQQPPK----PIPKQQGPGRDP---LQQDGTPKSISSQQPEKIKSQ 250
Query: 76 PPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRA 135
PP + GPT H+++ P+ RP + R S P+ P
Sbjct: 251 PPGT-----GKPIQGPTQTPQTDHAKL----PLQRDASRPQTKQADIVRGESVKPSLP-- 299
Query: 136 RAARAISNQSSPPPPP 151
++ Q +P PP
Sbjct: 300 SPSKPPIQQPTPGKPP 315
Score = 32.0 bits (71), Expect = 0.60
Identities = 40/167 (23%), Positives = 68/167 (40%), Gaps = 20/167 (11%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAA 89
S P + PPL P+ SPS++ K PP A +P PP P+ P A
Sbjct: 695 SKAPEPKKPPPLVKQPTLHGSPSAKAK---QPPEA-DSLSKPAPPKEPSVPSEQDKAPVA 750
Query: 90 G---PTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
++ + + S TKP P ++ A ++ +P + A +QS
Sbjct: 751 DDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKT----TPPLKTDSAKPSQSF 806
Query: 147 PP-----PPPPSRA----RSRSLRLSAPGSRHDAEKASERNRLRRKK 184
PP P S+A S S +S PG +++ + + +++K+
Sbjct: 807 PPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKE 853
Score = 31.2 bits (69), Expect = 1.0
Identities = 45/181 (24%), Positives = 56/181 (30%), Gaps = 55/181 (30%)
Query: 42 PGPPSRSRSPSSRLKLPAD------PPRALPGSPEPP-----PPPPPA------------ 78
PGP PS K A PP PG+ +PP P PPA
Sbjct: 326 PGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQ 385
Query: 79 -APHVLGARVAAG------------PTHRLSAS---------HSRVSSRGPVGTKPKRPG 116
P L G PT ++ S + GP T ++PG
Sbjct: 386 PGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG 445
Query: 117 QGR----RAGARMRSA------APASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPG 166
G+ +AG SA P S A+ Q P PPP + S PG
Sbjct: 446 PGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPG 505
Query: 167 S 167
S
Sbjct: 506 S 506
Score = 30.8 bits (68), Expect = 1.3
Identities = 37/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLP---ADPPRALPGSPEPPPPPPPAAPHVLGAR 86
S QP +T P SP + P A P + L +PEP PPP L
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPG-QGRRAGARMRSAAPASPR----ARAARAI 141
+A A +S P PK P + A + P P+ +
Sbjct: 716 PSAKAKQPPEA--DSLSKPAP----PKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSS 769
Query: 142 SNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASE 176
S+ ++ P P S+ +S++ + P + D+ K S+
Sbjct: 770 SSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQ 804
Score = 30.0 bits (66), Expect = 2.3
Identities = 42/180 (23%), Positives = 67/180 (37%), Gaps = 25/180 (13%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPS------RTCPP---LPGPPSRSRSPSSRLKLPADPP 62
K +K KP + P S PP +T P P P +SR S L D P
Sbjct: 857 KAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAP 916
Query: 63 RALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAG 122
++ P +P+ V G G + S + + +S+ G G P G
Sbjct: 917 KSQPTTPQET---------VTGKLFGFGAS-IFSQASNLISTAGQPG-----PHSQSGPG 961
Query: 123 ARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRR 182
A M+ APA + ++ + PP P+++ AP + KA + ++R
Sbjct: 962 APMKQ-APAPSQPPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKR 1020
Score = 30.0 bits (66), Expect = 2.3
Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 3/43 (6%)
Query: 113 KRPGQGRRAGARMRSAAPASPRA---RAARAISNQSSPPPPPP 152
++P +G+ S+ PA PR ++ IS Q PPPPPP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP 2412
Score = 29.3 bits (64), Expect = 3.9
Identities = 19/62 (30%), Positives = 23/62 (37%), Gaps = 22/62 (35%)
Query: 19 WKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPA 78
++ SSL A+ PP PP P PP P PPP PPP
Sbjct: 2394 FRSSSLDISAQPPPPPPPPPPPPPPPP----------------------PPPPPPLPPPT 2431
Query: 79 AP 80
+P
Sbjct: 2432 SP 2433
Score = 28.1 bits (61), Expect = 8.6
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 44 PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGAR 86
PP+ + SPS K D S PP P PA P + +R
Sbjct: 72 PPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKSR 114
Score = 28.1 bits (61), Expect = 8.6
Identities = 32/140 (22%), Positives = 49/140 (35%), Gaps = 12/140 (8%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPG----SPEPPPPPPPAAPHVLGARVAAGPTHRLSA 97
P PS S+ P + P PP PG P P PPA P L +A P
Sbjct: 296 PSLPSPSKPPIQQ-PTPGKPPAQQPGHEKSQPG--PAKPPAQPSGLTKPLAQQPGTVKPP 352
Query: 98 SHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARA-----ARAISNQSSPPPPPP 152
+++ P ++ G+ S+ P+A A + + Q P PP
Sbjct: 353 VQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPT 412
Query: 153 SRARSRSLRLSAPGSRHDAE 172
+ + PG + A+
Sbjct: 413 QQVGTPKPLAQQPGLQSPAK 432
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 52.4 bits (124), Expect = 4e-07
Identities = 58/190 (30%), Positives = 80/190 (42%), Gaps = 28/190 (14%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSR--------LKLPADPPR 63
+ HS+ + P+ + + +T P LP P + + PS + LK+P P
Sbjct: 195 RSHSRSPRHRTKSRSPSPAPEKKEKT-PELPEPSVKVKEPSVQEATSTSDILKVPKPEP- 252
Query: 64 ALPGSPEPPPPPPPAAPHVLGARVAAGPTHRL-SASHSRVSSRGPVGTKPKRPGQGRRAG 122
PEP P P + P R S S SR SR P T+P+R R
Sbjct: 253 ----IPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRR-----RHR 303
Query: 123 ARMRSAAPA---SPRARAA--RAISNQSSPPPPPPSRARS---RSLRLSAPGSRHDAEKA 174
+R RS +P SPR R + R + PPPP R+RS R R SA S + +
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSS 363
Query: 175 SERNRLRRKK 184
S R+R KK
Sbjct: 364 SSRSRSPPKK 373
Score = 52.0 bits (123), Expect = 6e-07
Identities = 50/156 (32%), Positives = 62/156 (39%), Gaps = 26/156 (16%)
Query: 21 PSSLIHPARSNQPPSRTCPPLPGPPSRSRSPS--------SRLKLPADPPRALPGSPEPP 72
PS P R P P PP R RSPS R P+ PP+ SP PP
Sbjct: 561 PSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPP 620
Query: 73 --------PPPPPAAPHVLGARVAAGP-THRLSASHSRVSSRGPVGTKPKRPGQGRRAGA 123
PPP H + + P T R S S +SS+ G+ P R + R+
Sbjct: 621 PKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS---LSSKHRKGSSPSRSTREARSPQ 677
Query: 124 RMRSAAPASPRARAARAISNQSSPPPPPPSRARSRS 159
+ +P SPR RA Q+S PPP R S S
Sbjct: 678 PNKRHSP-SPRPRAP-----QTSSSPPPVRRGASSS 707
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/170 (28%), Positives = 62/170 (36%), Gaps = 28/170 (16%)
Query: 29 RSNQPPSRTCPPLPGPPSRSRSP-SSRLKLPADPPRALPGSPEPPPPP-----PPAAPHV 82
R PSR+ P P + SP R + P+ PP SP P PPP P P
Sbjct: 520 RRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR- 578
Query: 83 LGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAIS 142
R + P R S S R S P P + R+A+P P R A
Sbjct: 579 --RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPP-------PKRRTASPPPPPKRRA---- 625
Query: 143 NQSSPPP-------PPPSRARSRSLRLSAPGSRHDAEKASERNRLRRKKR 185
SPPP PPP + S + +P K S +R R+ R
Sbjct: 626 -SPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
Score = 47.0 bits (110), Expect = 2e-05
Identities = 47/157 (29%), Positives = 60/157 (38%), Gaps = 20/157 (12%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPA----DPPRALPGSPEPPP------PPPPAAPHV 82
PP R P P P R+ SP R + P+ PP SP PPP PPPP
Sbjct: 566 PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR- 624
Query: 83 LGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAIS 142
A + P R+S S PV TK + P ++ R + S R AR+
Sbjct: 625 --ASPSPPPKRRVSHSPPPKQRSSPV-TKRRSPS----LSSKHRKGSSPSRSTREARSPQ 677
Query: 143 NQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNR 179
P P RA S S P R A + +R +
Sbjct: 678 PNKRHSPSPRPRAPQTSS--SPPPVRRGASSSPQRRQ 712
Score = 47.0 bits (110), Expect = 2e-05
Identities = 42/143 (29%), Positives = 56/143 (39%), Gaps = 11/143 (7%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPP------PPP--- 77
P R + P R PP+ S S P R P PP+ SP PPP PPP
Sbjct: 586 PRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRR-ASPSPPPKRRVSHSPPPKQR 644
Query: 78 AAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARA 137
++P + HR +S SR + KR R A S++P R A
Sbjct: 645 SSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGA 704
Query: 138 ARAISNQSSPPPPP-PSRARSRS 159
+ + + SP P P R SR+
Sbjct: 705 SSSPQRRQSPSPSTRPIRRVSRT 727
Score = 45.8 bits (107), Expect = 4e-05
Identities = 49/177 (27%), Positives = 69/177 (38%), Gaps = 15/177 (8%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEP 71
K S+ + S P R ++ SR+ P P R R PS R + P PR +P P
Sbjct: 283 KSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRR-PSPRRRTP---PRRMP----P 334
Query: 72 PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPA 131
PP + V R ++ S+S S SR P PKR R R+ + A
Sbjct: 335 PPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRL--SPSA 392
Query: 132 SPRARAARAISNQSSPP-----PPPPSRARSRSLRLSAPGSRHDAEKASERNRLRRK 183
SP R R + PP P P R+R R+S R + + +R+
Sbjct: 393 SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRE 449
Score = 42.7 bits (99), Expect = 3e-04
Identities = 54/227 (23%), Positives = 77/227 (33%), Gaps = 30/227 (13%)
Query: 6 APAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSP---SSRLKLPADPP 62
+P + +R S + SS +RS PP + PP R+ SP + RL A PP
Sbjct: 343 SPVRRRRRSSASLSGSSSSSSSSRSRSPPKK-------PPKRTSSPPRKTRRLSPSASPP 395
Query: 63 RALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAG 122
R P PP PPP H ++R S VS G K G +R
Sbjct: 396 RR-RHRPSPPATPPPKTRH----SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRES 450
Query: 123 ARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRR 182
S AP + + + ++ S + R R S D+ +S R
Sbjct: 451 P---SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP 507
Query: 183 KKRLVLGRGGGGECAHAHEWECARRMRRGCRTLTARRPLDSGRGLSP 229
K+ +H E RR R + P + SP
Sbjct: 508 KR------------SHVKNGEVGRRRRHSPSRSASPSPRKRQKETSP 542
Score = 33.5 bits (75), Expect = 0.21
Identities = 35/166 (21%), Positives = 61/166 (36%), Gaps = 14/166 (8%)
Query: 27 PARSNQPPSRTC-PPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPH---- 81
P+ S +P R P P ++ SPS + R++ GSPEP PPA P
Sbjct: 714 PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQS 773
Query: 82 ---------VLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPAS 132
+ + A PT S + G K K+ + ++ +
Sbjct: 774 QSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKK 833
Query: 133 PRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERN 178
+A AA A + + + ++ ++AP + + E +E N
Sbjct: 834 EKAVAAAAAAAVTPAAIAAATTTLAQEEPVAAPEPKKETESEAEDN 879
Score = 33.1 bits (74), Expect = 0.27
Identities = 49/193 (25%), Positives = 63/193 (32%), Gaps = 65/193 (33%)
Query: 27 PARSNQPPSRT--CPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPP------------ 72
P R++ PP +T P PP R PS PA PP SP P
Sbjct: 375 PKRTSSPPRKTRRLSPSASPPRRRHRPSP----PATPPPKTRHSPTPQQSNRTRKSRVSV 430
Query: 73 --------------------PPPPPAAPHV--------LGARVAAGPT------HRLSAS 98
P P P V G ++AA + +R
Sbjct: 431 SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQ 490
Query: 99 HSRVSSRGPVGTKPKRPGQG---------RRAGARMRSAAPASPRARAARAI---SNQSS 146
S S ++ +RP + RR + RSA+P SPR R + S
Sbjct: 491 QSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASP-SPRKRQKETSPRGRRRRS 549
Query: 147 PPPPPPSRARSRS 159
P PPP R RS S
Sbjct: 550 PSPPPTRRRRSPS 562
Score = 31.2 bits (69), Expect = 1.0
Identities = 44/175 (25%), Positives = 66/175 (37%), Gaps = 16/175 (9%)
Query: 12 KRHSKEVWKPSSLIHPARSNQP-PSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPE 70
K S+E + S +S P P R P+ RS S S R + + P P E
Sbjct: 159 KESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKE 218
Query: 71 PPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAP 130
P P + V V + ++ +V P+ +PK P + + + +
Sbjct: 219 KTPELPEPSVKVKEPSVQEATS---TSDILKVPKPEPI-PEPKEPSPEKNS-KKEKEKEK 273
Query: 131 ASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRRKKR 185
PR+R+ R+ S SR RSRS + P RH + S R R R
Sbjct: 274 TRPRSRS-RSKSR---------SRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPR 318
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 51.2 bits (121), Expect = 1e-06
Identities = 43/134 (32%), Positives = 49/134 (36%), Gaps = 22/134 (16%)
Query: 27 PARSNQPPSRTCPPLP-GPP---SRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAP 80
P N+P P P GPP +SRSP S P PP P+ PPPPP P P
Sbjct: 83 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142
Query: 81 HVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARA 140
G GP P G P QG RS P P+ +
Sbjct: 143 PPQGGNKPQGPP--------------PPGKPQGPPPQGDNKSRSSRS-PPGKPQGPPPQG 187
Query: 141 ISNQSSPPPPPPSR 154
NQ PPPPP +
Sbjct: 188 -GNQPQGPPPPPGK 200
Score = 49.3 bits (116), Expect = 4e-06
Identities = 38/127 (29%), Positives = 46/127 (36%), Gaps = 24/127 (18%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAPHVLGARVAAG 90
PP + P P ++SRS S P PP P+ PPPPP P P G G
Sbjct: 155 PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 214
Query: 91 PTHRLSASHSRVSSRGPVGTKPKRP---GQGRRAGARMRSAAPASPRARAARAISNQSSP 147
P P KP+ P G + AR P P + NQ
Sbjct: 215 P---------------PPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG----GNQPQG 255
Query: 148 PPPPPSR 154
PPPPP +
Sbjct: 256 PPPPPGK 262
Score = 49.3 bits (116), Expect = 4e-06
Identities = 39/122 (31%), Positives = 47/122 (38%), Gaps = 21/122 (17%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAPHVLGARVAAG 90
PP + P P S+SRS S P PP P+ PPPPP P P G G
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338
Query: 91 PTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSA--APASPRARAARAISNQSSPP 148
P P G P QG G++ RSA P P+ + +N PP
Sbjct: 339 PP--------------PPGKPQGPPPQG---GSKSRSARSPPGKPQGPPQQEGNNPQGPP 381
Query: 149 PP 150
PP
Sbjct: 382 PP 383
Score = 41.6 bits (96), Expect = 8e-04
Identities = 34/120 (28%), Positives = 44/120 (36%), Gaps = 22/120 (18%)
Query: 40 PLPGPP---SRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAPHVLGARVAAGPTHR 94
P PP ++ + P S P PP P+ PPPPP P P G GP
Sbjct: 36 PQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-- 93
Query: 95 LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSR 154
P G P QG + +R + P P+ + NQ PPPPP +
Sbjct: 94 ------------PPGKPQGPPPQGDK--SRSPRSPPGKPQGPPPQG-GNQPQGPPPPPGK 138
Score = 40.4 bits (93), Expect = 0.002
Identities = 28/85 (32%), Positives = 35/85 (41%), Gaps = 9/85 (10%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPT 92
PP + P P S+SRS S P PP+ +P+ PPPP P A A P
Sbjct: 341 PPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQP- 399
Query: 93 HRLSASHSRVSSRGPVGTKPKRPGQ 117
+ R P G +P RP Q
Sbjct: 400 --------QGPPRPPQGGRPSRPPQ 416
Score = 38.5 bits (88), Expect = 0.006
Identities = 38/145 (26%), Positives = 51/145 (35%), Gaps = 23/145 (15%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPE-PPPPPPPAAPHVLGARVA 88
S PP + P P ++ + P P PP P+ PPPP P P G
Sbjct: 173 SRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQG---- 228
Query: 89 AGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP 148
+ S+R P G P QG + P P+ + + PP
Sbjct: 229 ---------DNKSQSARSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPP 278
Query: 149 -------PPPPSRARSRSLRLSAPG 166
PPP ++SRS R S PG
Sbjct: 279 PPGKPQGPPPQGGSKSRSSR-SPPG 302
Score = 36.2 bits (82), Expect = 0.032
Identities = 38/154 (24%), Positives = 50/154 (32%), Gaps = 22/154 (14%)
Query: 22 SSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPP----- 76
SS P + PP + GPP P + P+ P +P PPP
Sbjct: 172 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231
Query: 77 ----------PAAPHVLGARVAAGPTHRLSASHSRVSSRG--PVGTKP--KRPGQGRRAG 122
P P G GP G P G P K G + G
Sbjct: 232 SQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGG 291
Query: 123 ARMRS--AAPASPRARAARAISNQSSPPPPPPSR 154
++ RS + P P+ + NQ PPPPP +
Sbjct: 292 SKSRSSRSPPGKPQGPPPQG-GNQPQGPPPPPGK 324
Score = 35.4 bits (80), Expect = 0.054
Identities = 41/148 (27%), Positives = 53/148 (35%), Gaps = 24/148 (16%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPE-PPPPPPPAAPHVLGA 85
P PP + P P ++ + P P PP P+ PPPP P P G
Sbjct: 47 PQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106
Query: 86 RVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQS 145
+ SR S R P G P QG + P P+ + +
Sbjct: 107 K-------------SR-SPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQ 151
Query: 146 SPPPP-----PPSRA--RSRSLRLSAPG 166
PPPP PP + +SRS R S PG
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSR-SPPG 178
Score = 32.0 bits (71), Expect = 0.60
Identities = 32/135 (23%), Positives = 42/135 (31%), Gaps = 20/135 (14%)
Query: 22 SSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPH 81
SS P + PP + GPP P + P+ P +P PPP
Sbjct: 296 SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSK 355
Query: 82 VLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAI 141
AR G +GP P++ G + P P+A A
Sbjct: 356 SRSARSPPG------------KPQGP----PQQEGNNPQGPPPPAGGNPQQPQAPPA--- 396
Query: 142 SNQSSPPPPPPSRAR 156
Q PP PP R
Sbjct: 397 -GQPQGPPRPPQGGR 410
>gi|150170729 microtubule associated serine/threonine kinase 3 [Homo
sapiens]
Length = 1309
Score = 50.8 bits (120), Expect = 1e-06
Identities = 59/199 (29%), Positives = 77/199 (38%), Gaps = 46/199 (23%)
Query: 16 KEVWKPSSLIHPARSNQP---------------PSRTCPPLPGPPSRSRSPSSRLKLPAD 60
K++ K +S++H +RS P+ + P P P RS +P A
Sbjct: 1077 KKISKQTSVLHTSRSFSSGLHHSLSSSESLPGSPTHSLSPSPTTPCRSPAPDVPADTTAS 1136
Query: 61 PPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRR 120
PP A P S P P AAG T R S+ H + G P RP GRR
Sbjct: 1137 PPSASPSSSSPASP------------AAAGHT-RPSSLHGLAAKLG-----PPRPKTGRR 1178
Query: 121 AGARMRSAAPASPRARAARAISNQSSPPP---PPPSRARSRSLRLS------APGSRHDA 171
+ S+ P SP A + SP P PP+ ARS LR G R D
Sbjct: 1179 ---KSTSSIPPSPLACPPISAPPPRSPSPLPGHPPAPARSPRLRRGQSADKLGTGERLDG 1235
Query: 172 EKASERNRLRRKKRLVLGR 190
E A R R + +V+ R
Sbjct: 1236 E-AGRRTRGPEAELVVMRR 1253
Score = 35.0 bits (79), Expect = 0.071
Identities = 39/155 (25%), Positives = 56/155 (36%), Gaps = 10/155 (6%)
Query: 19 WKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPE-------P 71
W S + S+QP P L S P + P P+
Sbjct: 755 WTSSGSSCQSSSSQPERGPSPSLLNTISLDTMPKFAFSSEDEGVGPGPAGPKRPVFILGE 814
Query: 72 PPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPK--RPGQGRRAGARMRSAA 129
P PPP A P + + T LS + R +S G + P+ G+GRR G R A
Sbjct: 815 PDPPPAATPVMPKPSSLSADTAALSHARLRSNSIGARHSTPRPLDAGRGRRLGG-PRDPA 873
Query: 130 PASPRARAARAISNQSSPPPPPPSRARSRSLRLSA 164
P RA ++ S P + + SL ++A
Sbjct: 874 PEKSRASSSGGSGGGSGGRVPKSASVSALSLIITA 908
Score = 31.2 bits (69), Expect = 1.0
Identities = 22/50 (44%), Positives = 26/50 (52%), Gaps = 2/50 (4%)
Query: 12 KRHSKEVWKPSSLIHPARSNQPPSRTCPPLPG-PPSRSRSPSSRLKLPAD 60
+R S PS L P S PP R+ PLPG PP+ +RSP R AD
Sbjct: 1177 RRKSTSSIPPSPLACPPIS-APPPRSPSPLPGHPPAPARSPRLRRGQSAD 1225
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 50.4 bits (119), Expect = 2e-06
Identities = 55/180 (30%), Positives = 72/180 (40%), Gaps = 34/180 (18%)
Query: 6 APAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGP--PSRSRSPSSR----LKLPA 59
+P++ +K+ +PS A R P P P SR PSS P
Sbjct: 649 SPSRAWSPRAKQAPRPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPW 708
Query: 60 DPPRALP-GSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQG 118
+P R SP P PPPPP +P S S VS P T+ + P +
Sbjct: 709 EPGRGSSMSSPPPLPPPPPMSP---------------SWSERSVSPLRPE-TEARPPSRQ 752
Query: 119 RRA--------GARMRSAAPASPRARAARAISNQSSP---PPPPPSRARSRSLRLSAPGS 167
+A AR +SA+P S A R S +P PPPPP R RS + + PGS
Sbjct: 753 LQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPARPGS 812
Score = 44.3 bits (103), Expect = 1e-04
Identities = 39/135 (28%), Positives = 52/135 (38%), Gaps = 31/135 (22%)
Query: 23 SLIHPARSNQPPSRTCPPLPGP----PSRSRSPSSRLKLPADP-PRALPGSPEPPPPPPP 77
S + P +PPSR L +R +S S R +P P + P +P PPPPPPP
Sbjct: 738 SPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPP 797
Query: 78 AAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARA 137
P + R P +P RPG GA + P SP
Sbjct: 798 PPPRM----------------------RSP---QPARPGSAAVPGAAF-APIPRSPLPAG 831
Query: 138 ARAISNQSSPPPPPP 152
+ ++ SP P PP
Sbjct: 832 PSSCTSPRSPLPAPP 846
Score = 42.7 bits (99), Expect = 3e-04
Identities = 50/156 (32%), Positives = 53/156 (33%), Gaps = 17/156 (10%)
Query: 27 PARSNQPPSRTCPPLPGP--PSRSRSPSSRLKLPADPPRA--------LPGSPEPPPPPP 76
P S P S PGP P R S SS LP PP + P PE PP
Sbjct: 690 PGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSPLRPETEARPP 749
Query: 77 PAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKR----PGQGRRAGARMRSAAPAS 132
L AR R SAS + P P R P RMRS PA
Sbjct: 750 SRQLQALLARNIINAARRKSASPRSAGAENPRPFSPPRAPPPPPPPPPPPPRMRSPQPAR 809
Query: 133 PRARA---ARAISNQSSPPPPPPSRARSRSLRLSAP 165
P + A A SP P PS S L AP
Sbjct: 810 PGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPAP 845
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 50.4 bits (119), Expect = 2e-06
Identities = 42/134 (31%), Positives = 51/134 (38%), Gaps = 23/134 (17%)
Query: 27 PARSNQPPSRTCPPLP-GPP---SRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAP 80
P N+P P P GPP +SRSP S P PP P+ PPPPP P P
Sbjct: 62 PQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 121
Query: 81 HVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARA 140
G GP P G P QG + +R + P P+ +
Sbjct: 122 PPQGGNRPQGPP--------------PPGKPQGPPPQGDK--SRSPRSPPGKPQGPPPQG 165
Query: 141 ISNQSSPPPPPPSR 154
NQ PPPPP +
Sbjct: 166 -GNQPQGPPPPPGK 178
Score = 46.2 bits (108), Expect = 3e-05
Identities = 46/169 (27%), Positives = 58/169 (34%), Gaps = 18/169 (10%)
Query: 27 PARSNQPPSRTCPPLP-GPP---SRSRSPSSRLKLPADPPRA---LPGSPEPPP-----P 74
P N+P P P GPP +SRSP S P PP P P PPP P
Sbjct: 123 PQGGNRPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 182
Query: 75 PPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPR 134
PP G P SS+ P G P QG + P P+
Sbjct: 183 PPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQ 241
Query: 135 ARAARAISNQSSPPPP-----PPSRARSRSLRLSAPGSRHDAEKASERN 178
+ + PPPP PP++ S+S +P + E N
Sbjct: 242 GPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGN 290
Score = 46.2 bits (108), Expect = 3e-05
Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 24/121 (19%)
Query: 39 PPLPGPPS-------RSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAPHVLGARVAA 89
PP PG P +SRS S P PP P+ PPPPP P P G
Sbjct: 193 PPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 252
Query: 90 GPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPP 149
GP P G P QG RS P P+ + +N PPP
Sbjct: 253 GPP--------------PPGKPQGPPAQGGSKSQSARS-PPGKPQGPPQQEGNNPQGPPP 297
Query: 150 P 150
P
Sbjct: 298 P 298
Score = 39.3 bits (90), Expect = 0.004
Identities = 32/111 (28%), Positives = 40/111 (36%), Gaps = 19/111 (17%)
Query: 46 SRSRSPSSRLKLPADPPRALPGSPEPPPPPP--PAAPHVLGARVAAGPTHRLSASHSRVS 103
S+ SPS P P P+ PPPPP P P G GP
Sbjct: 24 SQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPP----------- 72
Query: 104 SRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSR 154
P G P QG + +R + P P+ + NQ PPPPP +
Sbjct: 73 ---PPGKPQGPPPQGDK--SRSPRSPPGKPQGPPPQG-GNQPQGPPPPPGK 117
Score = 38.5 bits (88), Expect = 0.006
Identities = 31/96 (32%), Positives = 39/96 (40%), Gaps = 14/96 (14%)
Query: 27 PARSNQPPSRTCPPLP-GPP----SRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPH 81
P N+P P P GPP S+S+S S P PP+ +P+ PPPP P
Sbjct: 245 PQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQ 304
Query: 82 VLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQ 117
A A P + R P G +P RP Q
Sbjct: 305 QPQAPPAGQP---------QGPPRPPQGGRPSRPPQ 331
Score = 38.1 bits (87), Expect = 0.008
Identities = 34/128 (26%), Positives = 43/128 (33%), Gaps = 15/128 (11%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPE-PPPPPPPAAPHVLGARVA 88
S PP + P P ++ + P P PP P+ PPPP P P G
Sbjct: 212 SQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGG--- 268
Query: 89 AGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPP 148
S S S S G P++ G + P P+A A Q P
Sbjct: 269 -------SKSQSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPA----GQPQGP 317
Query: 149 PPPPSRAR 156
P PP R
Sbjct: 318 PRPPQGGR 325
Score = 34.7 bits (78), Expect = 0.092
Identities = 38/134 (28%), Positives = 48/134 (35%), Gaps = 23/134 (17%)
Query: 40 PLPGPPSRSRSPSSRLKLPADPPRALPGSPE-PPPPPPPAAPHVLGARVAAGPTHRLSAS 98
P P ++ + P P PP P+ PPPP P P G +
Sbjct: 39 PSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDK------------ 86
Query: 99 HSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPP------PPP 152
SR S R P G P QG + P P+ + + PPP PPP
Sbjct: 87 -SR-SPRSPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNRPQGPPPPGKPQGPPP 143
Query: 153 SRARSRSLRLSAPG 166
+SRS R S PG
Sbjct: 144 QGDKSRSPR-SPPG 156
>gi|33457336 chromosome 14 open reading frame 4 [Homo sapiens]
Length = 796
Score = 50.4 bits (119), Expect = 2e-06
Identities = 53/175 (30%), Positives = 67/175 (38%), Gaps = 21/175 (12%)
Query: 2 NSCFAPAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADP 61
NS A A R + L +P P T PP P + P+S LP P
Sbjct: 217 NSSSAAASVASRRGTHGGLVTGLPNPGGGGGP-QLTVPPNLLPQTLLNGPASAAVLPPPP 275
Query: 62 PRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGP-------VGTKPKR 114
P AL GS PP P PP AP G G T +SA+ S SS VG KR
Sbjct: 276 PHAL-GSRGPPTPAPPGAP---GGPACLGGTPGVSATSSSASSSTSSSVAEVGVGAGGKR 331
Query: 115 PG------QGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLS 163
PG Q R + R+ A A + ++ N++ P R L L+
Sbjct: 332 PGSVSSTDQERELKEKQRN---AEALAELSESLRNRAEEWASKPKMVRDTLLTLA 383
Score = 36.6 bits (83), Expect = 0.024
Identities = 30/94 (31%), Positives = 38/94 (40%), Gaps = 11/94 (11%)
Query: 71 PPPPPPPAAPHV-LGARVAAGPTHRLSASHSRVSSRGPVGT----KPKRPGQGRRAGARM 125
PPPPPPP PH + P + S + +S +GT K A AR
Sbjct: 596 PPPPPPPLGPHSNRTTPPESAPQNGPSPMAALMSVADTLGTAHSPKDGSSVHSTTASARR 655
Query: 126 RSAAPASP------RARAARAISNQSSPPPPPPS 153
S++P SP R A+R PPPPS
Sbjct: 656 NSSSPVSPASVPGQRRLASRNGDLNLQVAPPPPS 689
Score = 30.4 bits (67), Expect = 1.7
Identities = 33/124 (26%), Positives = 44/124 (35%), Gaps = 8/124 (6%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101
P PP S S +LP L G P P P P L R + + ++ SR
Sbjct: 174 PPPPVSLGSSSHTARLP----NGLGGPNGFPKPTPEEGPPELN-RQSPNSSSAAASVASR 228
Query: 102 VSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLR 161
+ G + T PG G G + P ++ + PPPPP SR
Sbjct: 229 RGTHGGLVTGLPNPGGG---GGPQLTVPPNLLPQTLLNGPASAAVLPPPPPHALGSRGPP 285
Query: 162 LSAP 165
AP
Sbjct: 286 TPAP 289
Score = 29.6 bits (65), Expect = 3.0
Identities = 37/132 (28%), Positives = 48/132 (36%), Gaps = 11/132 (8%)
Query: 43 GPPSRSRSPSSRL--KLPADPPRALPGSPEPPPPP-----PPAAPHVLGARVAAGPTHRL 95
G P P L P P + S P PP PPAAP GA AA R
Sbjct: 488 GVPGADMLPQPYLDASCPMLPTALVSLSRAPSAPPGTGALPPAAPSGRGA--AASLRKRK 545
Query: 96 SASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRA 155
++ S+ G + K Q ++ A A + A A + + PPPPP
Sbjct: 546 ASPEPPDSAEGAL--KLGEEQQRQQWMANQSEALKLTMSAGGFAAPGHAAGGPPPPPPPL 603
Query: 156 RSRSLRLSAPGS 167
S R + P S
Sbjct: 604 GPHSNRTTPPES 615
>gi|7706501 WW domain binding protein 11 [Homo sapiens]
Length = 641
Score = 50.4 bits (119), Expect = 2e-06
Identities = 41/128 (32%), Positives = 48/128 (37%), Gaps = 17/128 (13%)
Query: 27 PARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGAR 86
P +S P PP+PGPP P+ L+ P PP LP P P PP P + G R
Sbjct: 393 PPQSVPPSQIQAPPMPGPPPLGPPPAPPLR-PPGPPTGLPPGPPPGAPPFLRPPGMPGLR 451
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
GP RL GP +P P G G P P R +
Sbjct: 452 ---GPLPRLLPP-------GPPPGRPPGPPPGPPPG------LPPGPPPRGPPPRLPPPA 495
Query: 147 PPPPPPSR 154
PP PP R
Sbjct: 496 PPGIPPPR 503
Score = 35.4 bits (80), Expect = 0.054
Identities = 23/55 (41%), Positives = 23/55 (41%), Gaps = 7/55 (12%)
Query: 33 PPSRTCPPLPGPP-SRSRSPSSRLKLPADPPRALPGSPEP------PPPPPPAAP 80
PP R P PGPP P R P PP A PG P P PP PP P
Sbjct: 463 PPGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPAPPGIPPPRPGMMRPPLVPPLGP 517
Score = 32.3 bits (72), Expect = 0.46
Identities = 24/64 (37%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 27 PARSNQPPSRTCPPLP-GPPSRSRS--PSSRLKLPADPPRALPGSPEPPPPPPPAAPHVL 83
P QPPS GPP+R+ S P +P PP P P PP PPPP +
Sbjct: 157 PLPGAQPPSILKKTSAYGPPTRAVSILPLLGHGVPRLPPGRKPPGP-PPGPPPPQVVQMY 215
Query: 84 GARV 87
G +V
Sbjct: 216 GRKV 219
Score = 31.2 bits (69), Expect = 1.0
Identities = 22/56 (39%), Positives = 24/56 (42%), Gaps = 4/56 (7%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPP---PPPPPAAPHVLGA 85
PP R PP PP+ P R + PP P P PP PP P P VL A
Sbjct: 482 PPPRGPPPRLPPPAPPGIPPPRPGM-MRPPLVPPLGPAPPGLFPPAPLPNPGVLSA 536
Score = 30.0 bits (66), Expect = 2.3
Identities = 33/116 (28%), Positives = 40/116 (34%), Gaps = 27/116 (23%)
Query: 46 SRSRSPSSRLKLPADPPRALPGS-------PEPPPPPPPAAPHVLGARVAAGPTHRLSAS 98
S S S+ PP+++P S P PPP PP AP + R PT
Sbjct: 378 SHSDGTSTASSQQQAPPQSVPPSQIQAPPMPGPPPLGPPPAPPL---RPPGPPT------ 428
Query: 99 HSRVSSRGPVGTKP--KRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPP 152
+ P G P + PG G R P P R PPP PP
Sbjct: 429 --GLPPGPPPGAPPFLRPPGMPGLRGPLPRLLPPGPPPGR-------PPGPPPGPP 475
Score = 29.6 bits (65), Expect = 3.0
Identities = 19/64 (29%), Positives = 25/64 (39%), Gaps = 13/64 (20%)
Query: 20 KPSSLIHPARSNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAA 79
+P S++ + PP+R LP L PR PG P PPP P
Sbjct: 162 QPPSILKKTSAYGPPTRAVSILP-------------LLGHGVPRLPPGRKPPGPPPGPPP 208
Query: 80 PHVL 83
P V+
Sbjct: 209 PQVV 212
Score = 29.6 bits (65), Expect = 3.0
Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 13/62 (20%)
Query: 27 PARSNQPPSRTCPPLP------GPPSRSRSPSSRLKLPADPPRALPGSPEPP--PPPPPA 78
P R PP P LP GPP R P+ P P PG PP PP PA
Sbjct: 464 PGRPPGPPPGPPPGLPPGPPPRGPPPRLPPPA-----PPGIPPPRPGMMRPPLVPPLGPA 518
Query: 79 AP 80
P
Sbjct: 519 PP 520
Score = 28.9 bits (63), Expect = 5.1
Identities = 35/126 (27%), Positives = 47/126 (37%), Gaps = 20/126 (15%)
Query: 33 PPSRTCPPLPG--PPSRSRSPSSRLKLPADP--PRALPGSPEPPP----PPP-----PAA 79
PP R PP P PP R L P P P P +P P P PP P A
Sbjct: 487 PPPRLPPPAPPGIPPPRPGMMRPPLVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKA 546
Query: 80 PHVLGARVAAGPTHRLSAS------HSRVSSRGPVGTKPKRPGQGRRAGARMRSA-APAS 132
A + T +SA + ++ P + +R +G A + +S A
Sbjct: 547 DDTSAATIEKKATATISAKPQITNPKAEITRFVPTALRVRRENKGATAAPQRKSEDDSAV 606
Query: 133 PRARAA 138
P A+AA
Sbjct: 607 PLAKAA 612
>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
Length = 1003
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/161 (30%), Positives = 59/161 (36%), Gaps = 36/161 (22%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101
P P S SP P+DPP PPP PP+ P H AS
Sbjct: 245 PPAPHASSSP------PSDPPLFHCSDALTPPPLPPSNNL---------PAHPGPASQPP 289
Query: 102 VSSR--------GPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS 153
VSS GP+G P G G AP + A + PP PPPS
Sbjct: 290 VSSATMHLPLVLGPLGGAPTVEGPG----------APPFLASSLLSAAAKAQHPPLPPPS 339
Query: 154 RARSRSLRLSAPGSRHDAEKASERNRLRRKK---RLVLGRG 191
+ R R AP + H + + R RR RL+ GRG
Sbjct: 340 TLQGRRPRAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRG 380
Score = 33.1 bits (74), Expect = 0.27
Identities = 43/142 (30%), Positives = 55/142 (38%), Gaps = 36/142 (25%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPP---------AAPHVLGARVAAGPT 92
PGPPS +R P ++P P L G P PP PP A P L A P
Sbjct: 140 PGPPS-ARPPC---RVPPTTP--LNGGPGSLPPEPPSVSQAFPTLAGPGGLFPPRLADPV 193
Query: 93 HRLSASHSRVSSRG--PVGTKPKRPGQGRRA-----GARMRSA-------APASPRARAA 138
+S R RG P P P A GA +RS+ +P +P A ++
Sbjct: 194 PSGGSSSPRFLPRGNAPSPAPPPPPAISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSS 253
Query: 139 RA-------ISNQSSPPPPPPS 153
S+ +PPP PPS
Sbjct: 254 PPSDPPLFHCSDALTPPPLPPS 275
Score = 32.7 bits (73), Expect = 0.35
Identities = 43/153 (28%), Positives = 51/153 (33%), Gaps = 43/153 (28%)
Query: 33 PPSRTCPPL--PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPP----PPPAAPHVLGAR 86
PP PP PGPP P + P L S PPPP PPP+A
Sbjct: 572 PPEPLLPPPGGPGPPLAPGEP--------EGPSLLVASLLPPPPSDLLPPPSA------- 616
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSS 146
P L AS + + GP G+G GA S P S + + S
Sbjct: 617 ----PPSNLLASFLPLLALGPTA----GDGEGSAEGAGGPSGEPFSGLGDLSPLLFPPLS 668
Query: 147 PPP--------------PPPSRARSRSLRLSAP 165
PP PPS + LSAP
Sbjct: 669 APPTLIALNSALLAATLDPPSGTPPQPCVLSAP 701
Score = 32.0 bits (71), Expect = 0.60
Identities = 34/121 (28%), Positives = 42/121 (34%), Gaps = 21/121 (17%)
Query: 45 PSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSS 104
P SP + PP A P PP P P L P S S + +
Sbjct: 126 PGEGASPQMFHTVSPGPPSARPPCRVPPTTPLNGGPGSL-------PPEPPSVSQAFPTL 178
Query: 105 RGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSA 164
GP G P R + S +SPR N SP PPPP ++ L+A
Sbjct: 179 AGPGGLFPP------RLADPVPSGGSSSPRFLPR---GNAPSPAPPPPP-----AISLNA 224
Query: 165 P 165
P
Sbjct: 225 P 225
Score = 30.4 bits (67), Expect = 1.7
Identities = 16/44 (36%), Positives = 19/44 (43%), Gaps = 3/44 (6%)
Query: 39 PPLPGPPSRSRSPSSRLKLPADPPRALPGSP---EPPPPPPPAA 79
PPL PP+ S+ L DPP P P P P PP +
Sbjct: 665 PPLSAPPTLIALNSALLAATLDPPSGTPPQPCVLSAPQPGPPTS 708
Score = 30.4 bits (67), Expect = 1.7
Identities = 46/178 (25%), Positives = 61/178 (34%), Gaps = 35/178 (19%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPP----AAPHVLGARVA 88
P S PL + P + + P PP + + EP P PP A PH G+
Sbjct: 786 PLSEASSPLACLLQSLQIPPEQPEAPCLPPESPASALEPEPARPPLSALAPPH--GSPDP 843
Query: 89 AGP---THRLSASHSRVSSRGPVGTKPK-RPGQGRRAGARMRSAAPA------------- 131
P T R S R G G + RP +GR+ G+R A
Sbjct: 844 PVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSRREPGRLALKWGTRGGFNGQM 903
Query: 132 --SPR-----ARAARAISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRR 182
SPR + P PPP S L++ PG + S R R R+
Sbjct: 904 ERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKV-PPG----VVRKSRRGRRRK 956
Score = 29.3 bits (64), Expect = 3.9
Identities = 30/103 (29%), Positives = 38/103 (36%), Gaps = 8/103 (7%)
Query: 42 PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSR 101
P P S + SP + L P P PE P PP + L A P L+ H
Sbjct: 784 PPPLSEASSPLACLLQSLQIP---PEQPEAPCLPPESPASALEPEPARPPLSALAPPHGS 840
Query: 102 VSSRGPVGTKPKRPG-QGRRAGARMR----SAAPASPRARAAR 139
P + G +GRR G +R A PA R +R
Sbjct: 841 PDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPGSR 883
Score = 28.9 bits (63), Expect = 5.1
Identities = 35/140 (25%), Positives = 49/140 (35%), Gaps = 15/140 (10%)
Query: 29 RSNQPPSRTCPPLPGPPSRSRSPSSRLKL-----PADPPRALPGSPEP-------PPPPP 76
R+ P + L R R P + +L P P R+ P +P P P P
Sbjct: 347 RAQAPSASHSSSLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQ 406
Query: 77 PAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMR-SAAPASPRA 135
P P VL + PT S S + G P P + + R P+ P
Sbjct: 407 PILPSVLS--LLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGT 464
Query: 136 RAARAISNQSSPPPPPPSRA 155
+ S +P PP S+A
Sbjct: 465 TSGSLSSVPGAPAPPAASKA 484
Score = 28.9 bits (63), Expect = 5.1
Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 15/87 (17%)
Query: 58 PADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQ 117
P DPP P S + PP G R PT + SSR + +P
Sbjct: 926 PKDPPPPGPHSEDLKVPPGVVRKSRRGRRRKYNPTRNSN------SSRQDITLEP----- 974
Query: 118 GRRAGARMRSAAPASPRARAARAISNQ 144
R+A P PRAR R N+
Sbjct: 975 ----SPTARAAVPLPPRARPGRPAKNK 997
>gi|7662302 TBK1 binding protein 1 [Homo sapiens]
Length = 615
Score = 50.1 bits (118), Expect = 2e-06
Identities = 49/165 (29%), Positives = 67/165 (40%), Gaps = 31/165 (18%)
Query: 27 PARSNQPPSRTCP-PLPG-----PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAP 80
P + P S +CP P+P PPS +SPS + + P P P P PPPPPPP
Sbjct: 380 PQQRRSPASPSCPSPVPQRRSPVPPS-CQSPSPQRRSPVPPSCPAP-QPRPPPPPPPGER 437
Query: 81 HVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARA 140
+ A P+H + A G + +R GA A+P +A AA
Sbjct: 438 TLAERAYAKPPSHHVKA-----------GFQGRRSYSELAEGAAYAGASPPWLQAEAA-- 484
Query: 141 ISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRRKKR 185
+ P P R+ L PG +A E RLR +K+
Sbjct: 485 ----TLPKP------RAYGSELYGPGRPLSPRRAFEGIRLRFEKQ 519
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/133 (30%), Positives = 49/133 (36%), Gaps = 24/133 (18%)
Query: 44 PPSRSRSPSSRLKLPADPPRALPGSP--EPPPP----PPPAAPHVLGARVAAGPTHRLSA 97
P S+ SP+ + P+ P RA P P + P P P P P R A P S
Sbjct: 336 PLSQRHSPAPQCPSPSPPARAAPPCPPCQSPVPQRRSPVPPCPSPQQRRSPASP----SC 391
Query: 98 SHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARS 157
R PV + P RR+ AP Q PPPPPP R+
Sbjct: 392 PSPVPQRRSPVPPSCQSPSPQRRSPVPPSCPAP-------------QPRPPPPPPPGERT 438
Query: 158 RSLRLSA-PGSRH 169
+ R A P S H
Sbjct: 439 LAERAYAKPPSHH 451
>gi|190014636 hypothetical protein LOC286262 isoform 2 [Homo
sapiens]
Length = 678
Score = 50.1 bits (118), Expect = 2e-06
Identities = 50/162 (30%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 33 PPSRTCPPL-----PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARV 87
PP R L P P R SP R + P PP P P P P PPAAP G
Sbjct: 68 PPGRVSRLLERFDPPAAPRRRGSPE-RARPPPPPPPPAPPRPPPAAPSPPAAPGPRGG-- 124
Query: 88 AAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSP 147
A P R S + S P+ G R AGAR+ S ++P RA A SP
Sbjct: 125 GASPGARRSDFLQKTGSNS-FTVHPR--GLHRGAGARLLSNGHSAPEPRAGPANRLAGSP 181
Query: 148 P----------------PPPPSRARSRSLRLSAPGSRHDAEK 173
P PPPS + S P S +++
Sbjct: 182 PGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQR 223
Score = 33.9 bits (76), Expect = 0.16
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 14/104 (13%)
Query: 65 LPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGAR 124
+PG P PP P A V P R+ SR+ R P+R G RA
Sbjct: 42 VPGFPPAPPAPGAAQIRAAEVLVYGAPPGRV----SRLLERFDPPAAPRRRGSPERARPP 97
Query: 125 MRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSR 168
PA PR A SPP P R S PG+R
Sbjct: 98 PPPPPPAPPRPPPA-----APSPPAAPGPRGGGAS-----PGAR 131
>gi|190014638 hypothetical protein LOC286262 isoform 1 [Homo
sapiens]
Length = 650
Score = 50.1 bits (118), Expect = 2e-06
Identities = 50/162 (30%), Positives = 60/162 (37%), Gaps = 27/162 (16%)
Query: 33 PPSRTCPPL-----PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARV 87
PP R L P P R SP R + P PP P P P P PPAAP G
Sbjct: 68 PPGRVSRLLERFDPPAAPRRRGSPE-RARPPPPPPPPAPPRPPPAAPSPPAAPGPRGG-- 124
Query: 88 AAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSP 147
A P R S + S P+ G R AGAR+ S ++P RA A SP
Sbjct: 125 GASPGARRSDFLQKTGSNS-FTVHPR--GLHRGAGARLLSNGHSAPEPRAGPANRLAGSP 181
Query: 148 P----------------PPPPSRARSRSLRLSAPGSRHDAEK 173
P PPPS + S P S +++
Sbjct: 182 PGSGQWKPKVESGDPSLHPPPSPGTPSATPASPPASATPSQR 223
Score = 33.9 bits (76), Expect = 0.16
Identities = 32/104 (30%), Positives = 37/104 (35%), Gaps = 14/104 (13%)
Query: 65 LPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGAR 124
+PG P PP P A V P R+ SR+ R P+R G RA
Sbjct: 42 VPGFPPAPPAPGAAQIRAAEVLVYGAPPGRV----SRLLERFDPPAAPRRRGSPERARPP 97
Query: 125 MRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAPGSR 168
PA PR A SPP P R S PG+R
Sbjct: 98 PPPPPPAPPRPPPA-----APSPPAAPGPRGGGAS-----PGAR 131
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 50.1 bits (118), Expect = 2e-06
Identities = 40/122 (32%), Positives = 45/122 (36%), Gaps = 39/122 (31%)
Query: 39 PPLPGPPSRSRS-----PSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTH 93
PPLPG PS + + P K P PP A P+PPPPPPP P + PT
Sbjct: 1434 PPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPT- 1492
Query: 94 RLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPS 153
SS P P P PA P S PPPPPP+
Sbjct: 1493 --------PSSPPPPPLPPPPP--------------PAMP-----------SPPPPPPPA 1519
Query: 154 RA 155
A
Sbjct: 1520 AA 1521
Score = 46.2 bits (108), Expect = 3e-05
Identities = 61/236 (25%), Positives = 79/236 (33%), Gaps = 85/236 (36%)
Query: 33 PPSRTCPPLPGPPSR--------------------SRSP-----SSRLKLPADPPRALP- 66
PP R PP P PP R SP S P P RALP
Sbjct: 225 PPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPR 284
Query: 67 -----------GSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRP 115
S +PPPPPPPA H L ++ G ++ S H + P+G P
Sbjct: 285 QDTVIKHYQRPASAQPPPPPPPA--HALQHYLSCGGSYP-SMGHRANLACSPLGGGEPSP 341
Query: 116 GQGR---------RAGARMRSAAPA-------------------SPRARAAR----AISN 143
G G AGA R+ P SP + + A +
Sbjct: 342 GAGEPSKAGPSGATAGASGRATGPEAAGGGGAGGGGGGYRPIIQSPGYKTGKGGYGAAAG 401
Query: 144 QSSPPPPPPSRARSRSLRLSAPGSRHDAEKASERNRLRRKKRLVLGRGGGGECAHA 199
++ PPPP S A + L P + + KAS G GG G A++
Sbjct: 402 GATRPPPPRSTATPKCQSLGGPAAAYATGKAS-------------GAGGAGGQAYS 444
Score = 46.2 bits (108), Expect = 3e-05
Identities = 26/57 (45%), Positives = 28/57 (49%), Gaps = 5/57 (8%)
Query: 27 PARSNQPPSRTCPPLPG----PPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAA 79
P QPP PP P PP + +PSS P PP P P PPPPPPPAA
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPP-PAMPSPPPPPPPAA 1520
Score = 41.2 bits (95), Expect = 0.001
Identities = 36/121 (29%), Positives = 44/121 (36%), Gaps = 15/121 (12%)
Query: 58 PADPPRALPGSPEPPPPPP--PAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRP 115
PA P PG P+PPPPP P ++L + AA S+ S G P
Sbjct: 221 PAQTPPYRPGPPDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPER 280
Query: 116 GQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRL--SAPGSRHDAEK 173
R+ PAS + PPPPPP+ A L S P H A
Sbjct: 281 ALPRQDTVIKHYQRPASAQ-----------PPPPPPPAHALQHYLSCGGSYPSMGHRANL 329
Query: 174 A 174
A
Sbjct: 330 A 330
Score = 40.8 bits (94), Expect = 0.001
Identities = 20/48 (41%), Positives = 23/48 (47%), Gaps = 4/48 (8%)
Query: 33 PPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAP 80
PP+ T P P PP P+ LP+ PP P PPPPP P P
Sbjct: 1462 PPAPTPQPQPPPPPPPPQPA----LPSPPPLVAPTPSSPPPPPLPPPP 1505
Score = 37.7 bits (86), Expect = 0.011
Identities = 44/152 (28%), Positives = 52/152 (34%), Gaps = 45/152 (29%)
Query: 39 PPLPGPPSRSRSPSSR-LKLPA---DPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHR 94
PP P P ++S P+ L L A D P LP PPPP P VL + P
Sbjct: 764 PPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLP------PPPPQLLPSVLSHAPSPSP--- 814
Query: 95 LSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSR 154
S VG P R AP PPPPPP
Sbjct: 815 ---------SASKVGVHLLEPAT--------RDGAP---------------QPPPPPPPP 842
Query: 155 ARSRSLRLSAPGSRHDAEKASERNRLRRKKRL 186
L+L A H E A+ RLR ++ L
Sbjct: 843 PPPMPLQLEAHLRSHGLEPAAPSPRLRPEESL 874
Score = 37.0 bits (84), Expect = 0.019
Identities = 29/100 (29%), Positives = 38/100 (38%), Gaps = 15/100 (15%)
Query: 28 ARSNQPPSRTCPPL---PGPPSRSRSPSSRLKLPADPPRALPGSPEPPP---------PP 75
A SN P PPL PP+ +P+ + + P PP P P PPP PP
Sbjct: 1442 ANSNGTPE---PPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPP 1498
Query: 76 PPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRP 115
PP P A + P +A+ P P+ P
Sbjct: 1499 PPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDP 1538
Score = 37.0 bits (84), Expect = 0.019
Identities = 35/154 (22%), Positives = 58/154 (37%), Gaps = 26/154 (16%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAA 89
S+ PP + P P P + ++ S + PP P + P PP P P +L
Sbjct: 1689 SSAPPPKAPAPPPKPETPEKTTSEK------PPEQTPETAMPEPPAP-EKPSLL------ 1735
Query: 90 GPTHRLSASHSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPP 149
P + P+ + G+ R + + PA+ R AR ++ PPP
Sbjct: 1736 RPVEKEKEKEKVTRGERPLRGERATSGRQTRPERSLATGQPATSRLPKARPTKVKAEPPP 1795
Query: 150 PPPSRARSRSLRLSA---------PGSRHDAEKA 174
+ R + L+ + PGS D+E +
Sbjct: 1796 ----KKRKKWLKEAGGNATAGGGPPGSSSDSESS 1825
Score = 36.6 bits (83), Expect = 0.024
Identities = 24/67 (35%), Positives = 31/67 (46%), Gaps = 7/67 (10%)
Query: 21 PSSLIHPARSNQPPSRTCPP----LPGPPSRSRSPS---SRLKLPADPPRALPGSPEPPP 73
P L+ A P PP LP S + SPS S++ + P G+P+PPP
Sbjct: 778 PHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGAPQPPP 837
Query: 74 PPPPAAP 80
PPPP P
Sbjct: 838 PPPPPPP 844
Score = 33.9 bits (76), Expect = 0.16
Identities = 26/78 (33%), Positives = 31/78 (39%), Gaps = 11/78 (14%)
Query: 33 PPSRTCPPL----PGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARV- 87
PP + P + P P + L PA A P P PPPPPPP P L A +
Sbjct: 797 PPPQLLPSVLSHAPSPSPSASKVGVHLLEPATRDGA-PQPPPPPPPPPPPMPLQLEAHLR 855
Query: 88 -----AAGPTHRLSASHS 100
A P+ RL S
Sbjct: 856 SHGLEPAAPSPRLRPEES 873
Score = 33.1 bits (74), Expect = 0.27
Identities = 25/91 (27%), Positives = 36/91 (39%), Gaps = 20/91 (21%)
Query: 62 PRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVGTKPKRPGQGRRA 121
P+A G P PP P P+ G AGP +G P +P +
Sbjct: 974 PKAGAGPPPGPPAYDPYGPYCPGRASGAGP------------ETPGLGLDPNKPPE---- 1017
Query: 122 GARMRSAAPASPRARAARAISNQSSPPPPPP 152
+ S A P ++ +Q++PPPPPP
Sbjct: 1018 ---LPSTVNAEPLG-LIQSGPHQAAPPPPPP 1044
Score = 31.6 bits (70), Expect = 0.78
Identities = 25/88 (28%), Positives = 32/88 (36%), Gaps = 18/88 (20%)
Query: 34 PSRTCPPLPGPPSRSRSPSSRLKLP----ADPPRALPGSPE---PPPPPPPAAPHVLGAR 86
P R P P P+ +LP A+P + P PPPPPPP P +
Sbjct: 995 PGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSGPHQAAPPPPPPPPPPPAPASE 1054
Query: 87 VAAGPTHRLSASHSRVSSRGPVGTKPKR 114
G T + S TKPK+
Sbjct: 1055 PKGGLTSPIFCS-----------TKPKK 1071
Score = 29.3 bits (64), Expect = 3.9
Identities = 30/107 (28%), Positives = 38/107 (35%), Gaps = 19/107 (17%)
Query: 38 CPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSA 97
CPP PGP R K D P G P P P AGP SA
Sbjct: 1143 CPPNPGPDGPRRRGRKPTKAKRDGPPRPRGRPRIRPLEVP---------TTAGPA---SA 1190
Query: 98 SHSRVSSRGPVGTKPKRPGQGRRA----GARMRSAAPASPRARAARA 140
S ++ P G + G+GR+A G R+ P + +A
Sbjct: 1191 STPTDGAKKPRG---RGRGRGRKAEEAGGTRLEPLKPLKIKLSVPKA 1234
Score = 29.3 bits (64), Expect = 3.9
Identities = 32/116 (27%), Positives = 36/116 (31%), Gaps = 21/116 (18%)
Query: 50 SPSSRLKLPADPPRALPGSPEPPPPPPPAAPHVLGARVAAGPTHRLSASHSRVSSRGPVG 109
S SS + DPP A P P PP A A GP P+
Sbjct: 1397 SISSAISALDDPPLAGPKDTSTPDGPPLAP-----AAAVPGPP--------------PLP 1437
Query: 110 TKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPPPPPSRARSRSLRLSAP 165
P G + P +P A Q PPPPPP A L AP
Sbjct: 1438 GLPSANSNGTPEPPLLEEKPPPTPPP--APTPQPQPPPPPPPPQPALPSPPPLVAP 1491
Score = 28.1 bits (61), Expect = 8.6
Identities = 12/29 (41%), Positives = 16/29 (55%), Gaps = 5/29 (17%)
Query: 58 PADPPRALPGSP-----EPPPPPPPAAPH 81
P PP+++P S +P PP PA PH
Sbjct: 1306 PLSPPKSVPPSVPARGLQPQPPATPAVPH 1334
>gi|6912458 calcineurin binding protein 1 [Homo sapiens]
Length = 2220
Score = 49.7 bits (117), Expect = 3e-06
Identities = 51/188 (27%), Positives = 74/188 (39%), Gaps = 44/188 (23%)
Query: 7 PAKFLKRHSKEVWKPSSLIHPARSNQPPSRTCPPL-----------PGPPSRSRSPSSRL 55
PA ++R S KP PA + TCPP PGPP R ++
Sbjct: 1952 PADSVQRPSDAHTKP----RPALAAATTIITCPPSASASTLDQSKDPGPPRPHRPEATPS 2007
Query: 56 KLPADPP-----RALPGSPEPPPPP------------PPAAPHVLGARVAAGPTHRLSAS 98
P R G+ PP P PA PH A A G + +
Sbjct: 2008 MASLGPEGEELARVAEGTSFPPQEPRHSPQVKMAPTSSPAEPHCWPAEAALG-----TGA 2062
Query: 99 HSRVSSRGPVGTKPKRPGQGRRAGARMRSAAPASPRARAARAISNQSSPPP------PPP 152
S G + +P+R G+ + A + + + + P A +++A S+ S+ PP P P
Sbjct: 2063 EPTCSQEGKLRPEPRRDGEAQEAASETQPLS-SPPTAASSKAPSSGSAQPPEGHPGKPEP 2121
Query: 153 SRARSRSL 160
SRA+SR L
Sbjct: 2122 SRAKSRPL 2129
Score = 33.5 bits (75), Expect = 0.21
Identities = 23/71 (32%), Positives = 25/71 (35%), Gaps = 14/71 (19%)
Query: 36 RTCPPLPGPPSRSRSPSSR----------LKLPADPPRALPGSPEPPPPPPPAAPHVLGA 85
RT P LPG P+R R P SR + P P P P P P G
Sbjct: 1775 RTPPLLPGRPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTT----GT 1830
Query: 86 RVAAGPTHRLS 96
R P LS
Sbjct: 1831 RAGGHPEEPLS 1841
Score = 32.3 bits (72), Expect = 0.46
Identities = 45/192 (23%), Positives = 65/192 (33%), Gaps = 46/192 (23%)
Query: 30 SNQPPSRTCPPLPGPPSRSRSPSSRLKLPADPPRALPGSPEPP------PPPPPAA---- 79
S +P + C LPG +R + S P D LP +PP P P P
Sbjct: 1671 SERPGPKVCG-LPG--ARMTTDVSHKASPEDGQEGLPQPKKPPLADGSGPGPEPGGKVGL 1727
Query: 80 ----PHVLGARVAA--------------GPTHRLSASHSRVSSRGPVGTKPKRPGQGRRA 121
P + A +A GPT + S + V T P PG
Sbjct: 1728 LNHRPVAMDAGDSADQSGERKDKESPRAGPTEPMDTSEATVCHSDLERTPPLLPG----- 1782
Query: 122 GARMRSAAPASPRARAAR------AISNQSSPPPPPPSRARSRSLRLSAPGSRHDAEKAS 175
R A P +R +IS + P P P++ + G+R
Sbjct: 1783 ----RPARDRGPESRPTELSLEELSISARQQPTPLTPAQPAPAPAPATTTGTRAGGHPEE 1838
Query: 176 ERNRLRRKKRLV 187
+RL RK++L+
Sbjct: 1839 PLSRLSRKRKLL 1850
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.131 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,392,058
Number of Sequences: 37866
Number of extensions: 1180833
Number of successful extensions: 38506
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 967
Number of HSP's successfully gapped in prelim test: 2024
Number of HSP's that attempted gapping in prelim test: 12736
Number of HSP's gapped (non-prelim): 14419
length of query: 274
length of database: 18,247,518
effective HSP length: 101
effective length of query: 173
effective length of database: 14,423,052
effective search space: 2495187996
effective search space used: 2495187996
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.