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Search of human proteins with 116256464
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
(962 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 1942 0.0
gi|163965366 nascent polypeptide-associated complex alpha subuni... 134 4e-31
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 119 1e-26
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 119 1e-26
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 118 3e-26
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 118 3e-26
gi|210032580 SET domain containing 1B [Homo sapiens] 99 2e-20
gi|148806928 hypothetical protein LOC57482 [Homo sapiens] 97 9e-20
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 96 1e-19
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 96 2e-19
gi|110349719 titin isoform N2-A [Homo sapiens] 94 6e-19
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 92 2e-18
gi|150170670 piccolo isoform 2 [Homo sapiens] 91 4e-18
gi|150378539 piccolo isoform 1 [Homo sapiens] 91 4e-18
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 90 1e-17
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 89 2e-17
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 88 4e-17
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 87 7e-17
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 87 1e-16
gi|110832843 TBP-associated factor 4 [Homo sapiens] 85 4e-16
gi|47132519 Ras association and pleckstrin homology domains 1 is... 85 4e-16
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom... 84 5e-16
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom... 84 5e-16
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 84 5e-16
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap... 84 5e-16
gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1 pre... 84 8e-16
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 83 1e-15
gi|41281612 zinc finger protein 828 [Homo sapiens] 82 3e-15
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 81 4e-15
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 81 5e-15
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 1942 bits (5031), Expect = 0.0
Identities = 962/962 (100%), Positives = 962/962 (100%)
Query: 1 MISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKKFFGKKKRKESPSSTGSSTWKQSQTR 60
MISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKKFFGKKKRKESPSSTGSSTWKQSQTR
Sbjct: 1 MISTRVMDIKLREAAEGLGEDSTGKKKSKFKTFKKFFGKKKRKESPSSTGSSTWKQSQTR 60
Query: 61 NEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPESGQDATRPVRVFSQENVCDR 120
NEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPESGQDATRPVRVFSQENVCDR
Sbjct: 61 NEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPESGQDATRPVRVFSQENVCDR 120
Query: 121 IKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIK 180
IKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIK
Sbjct: 121 IKALQLKIQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIK 180
Query: 181 VSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKM 240
VSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKM
Sbjct: 181 VSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKM 240
Query: 241 RRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLP 300
RRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLP
Sbjct: 241 RRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLP 300
Query: 301 PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEG 360
PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEG
Sbjct: 301 PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEG 360
Query: 361 PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAA 420
PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAA
Sbjct: 361 PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAA 420
Query: 421 TSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIG 480
TSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIG
Sbjct: 421 TSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIG 480
Query: 481 TEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERP 540
TEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERP
Sbjct: 481 TEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERP 540
Query: 541 KAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPL 600
KAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPL
Sbjct: 541 KAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPL 600
Query: 601 ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA
Sbjct: 601 ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
Query: 661 PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLT 720
PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLT
Sbjct: 661 PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLT 720
Query: 721 VLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP 780
VLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP
Sbjct: 721 VLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP 780
Query: 781 DAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQ 840
DAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQ
Sbjct: 781 DAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQ 840
Query: 841 PPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLN 900
PPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLN
Sbjct: 841 PPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKLN 900
Query: 901 FKEGLQRGISLSHQNLAQSAVMMEKELHQLKRASYASTDQPSWMELARKKSQAWSDMPQI 960
FKEGLQRGISLSHQNLAQSAVMMEKELHQLKRASYASTDQPSWMELARKKSQAWSDMPQI
Sbjct: 901 FKEGLQRGISLSHQNLAQSAVMMEKELHQLKRASYASTDQPSWMELARKKSQAWSDMPQI 960
Query: 961 IK 962
IK
Sbjct: 961 IK 962
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 134 bits (337), Expect = 4e-31
Identities = 206/829 (24%), Positives = 274/829 (33%), Gaps = 94/829 (11%)
Query: 113 SQENVCDRIKALQLKIQCNVKMGPPP-PPGGLPAKRGEDAGMSSEDDGLP-RSPPEMSLL 170
S +N C + L L + + P PP G P + G+S P S P+
Sbjct: 713 SPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPT 772
Query: 171 HDVGPGTTIK--------VSVVSPDHVSDSTVSARI-----SDNSLAPVADFSYPA---E 214
D G T SP VS S + R S P+ + S P E
Sbjct: 773 EDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVE 832
Query: 215 SSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSP 274
+S +NS + + P S +++ L+ +E P V
Sbjct: 833 ASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVN 892
Query: 275 EERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSS 334
P G AP + P + P A + S + + P
Sbjct: 893 LPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 335 RPATPELAEPESAPTL-RVEPPSPPEGPPNPGPDGGKQDGEA----PPAGPCAPATDKA- 388
PATP P+ APT PPSP GP P P G A P GP P+ A
Sbjct: 953 GPATPS---PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 389 -EEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTP-PVL 446
V P SP T P+G +TPP P + +P+A +PK A TP L
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAA-----TPLPKGAPTTPAATL 1064
Query: 447 PDEEKGPPGP----APEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRP 502
P + GP P AP P P+ G T + P PA +PP+PK L P
Sbjct: 1065 PSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP---PAATPPSPKGGLATPP 1121
Query: 503 -AAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERA-APERK 560
A PAA+PP + P G+ AA P PK A PP GA A
Sbjct: 1122 HKGAPTTPAATPP-SPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPP 1180
Query: 561 AERGGAELRGAKKFSVSSCRARPRP--GVSRPLERASGRLPLARSGPVWRSEAALDDLQG 618
+ +GG K + P P G++ P + + P A + P + A +G
Sbjct: 1181 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-AATPPSPKGGLATPSPKG 1239
Query: 619 LPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED 678
P A P K P G A P A P P PA P PS
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP-PSPK 1298
Query: 679 RNP-------FPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLG 731
P P +T S K G T PK P
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKGSPG---------------------TPPPKGAPTPPA 1337
Query: 732 -TAPALRGT-RAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQ------PAPPDAG 783
T P+ +GT P+ K P P S + P P + T H+ P P G
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP-----PAATPSHKGGPAMTPPSPKRG 1392
Query: 784 PGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPG--ADGQPAPPWITVTRQKRRGTLDQP 841
P P+ +P + PL + P G + G PP +T K+ P
Sbjct: 1393 PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP 1452
Query: 842 PNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
+ P + K +P A P +EP S S P PA
Sbjct: 1453 ---KGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA 1498
Score = 112 bits (279), Expect = 2e-24
Identities = 166/720 (23%), Positives = 233/720 (32%), Gaps = 144/720 (20%)
Query: 273 SPEERPSSGQQDVA--PDRGPEPGPPAPLPPPGGARARRAR--LQHSSALTASVEEGGVP 328
+P P S + +A P +G P A P P G A + + A T +GG+
Sbjct: 1151 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLA 1210
Query: 329 GEDPSSRPATPELA-----------EPESAPTL-RVEPPSPPEGPPNPGPDGGKQDGEAP 376
P P TP P+ APT PPSP GP P P G A
Sbjct: 1211 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAAT 1270
Query: 377 P----AGPCAPATDKAEE--VVCAPEDVASPFPTAIPEGDTTPPE--------------- 415
P G P A VV P P T+ P+G TPP
Sbjct: 1271 PPSLKGGLATPPHKGAPNPAVVTPPSPKGGP-ATSPPKGAPTPPAATPPSPKGSPGTPPP 1329
Query: 416 ----TDPAAT-----------SEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEP 460
T PA T + PS++ GP KE P P + GP P P
Sbjct: 1330 KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSP 1389
Query: 461 EREAETEPERGAGTEPERIGTEPSTAPAP---------------SPPAPKSCLKHRPAAA 505
+R +G T P I P APA +PPA P +
Sbjct: 1390 KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAV------TPVSL 1443
Query: 506 SEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGG 565
+ PA S P +P + P +P+ P A + + + + + AP A G
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPK-QVATSSSPKKAPATPAPMGA 1502
Query: 566 AELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVW--RSEAALDDLQGLPEPQ 623
L S A P +S R P+A + + ++ A L + L P
Sbjct: 1503 PTLPAVIPSSPKEVPATP----------SSRRDPIAPTATLLSKKTPATLAPKEALIPPA 1552
Query: 624 HAKPGPRK-----LAERGPQDSGDRAAS----------------------PAGPRKSPQE 656
P P+K + P + AS PA SP+E
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 657 AAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL--------SLKYRDGAS--QEVKGV 706
A P P P P+ P + +SL S+ + GA+ Q KG+
Sbjct: 1613 APTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 707 KRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPE---------PLS 757
L+ L V P E P+ TAP +G + P+ PLS
Sbjct: 1673 PAKKGPTALKEVL-VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS 1731
Query: 758 SKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPG 817
+ P P P+ + + DA + P P + PL A + + P
Sbjct: 1732 TVAPAPLLPVQKDSS--KTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESAS 1789
Query: 818 ADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFV 877
P+PP TL PP Q+ P S PG + P + P + + +
Sbjct: 1790 VSAAPSPPVSLPLAPSPVPTL--PPKQQFLP------SSPGLVLESPSKPLAPADEDELL 1841
Score = 39.3 bits (90), Expect = 0.018
Identities = 31/123 (25%), Positives = 43/123 (34%), Gaps = 23/123 (18%)
Query: 435 VPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAP 494
+P EA T P E P+P+ E P A + +G T P P PAP
Sbjct: 1 MPGEATETVPATEQE-------LPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAP 53
Query: 495 KSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAER 554
+ C PL+AA P P ++ + P++ A P G
Sbjct: 54 QQC----------------PLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAP 97
Query: 555 AAP 557
AP
Sbjct: 98 EAP 100
Score = 33.1 bits (74), Expect = 1.3
Identities = 50/217 (23%), Positives = 68/217 (31%), Gaps = 45/217 (20%)
Query: 637 PQDSGDRAASPAGPRKSPQEAAAAPGTR--EPCPAAQEPAPSEDRN-----PFPVKLRST 689
PQ + A P S A PG PC A + P N P P + ST
Sbjct: 17 PQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIAST 76
Query: 690 SLSLKYRDGAS----------------QEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTA 733
L + + +S + G A + L + + P + P +A
Sbjct: 77 PLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAALALASPM-IAPTLKGTPSSSA 135
Query: 734 PALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEP 793
P AP K A PP L+S P + TL AP EP
Sbjct: 136 PLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP-----------SEP 184
Query: 794 RTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVT 830
+T + P+ P G P+PP I T
Sbjct: 185 KT----------NLNKVPSEVVPNPKGTPSPPCIVST 211
Score = 32.3 bits (72), Expect = 2.2
Identities = 62/275 (22%), Positives = 102/275 (37%), Gaps = 49/275 (17%)
Query: 128 IQCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGP------------ 175
+ C + P GLPAK+G A P S P ++ GP
Sbjct: 1657 VTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPI 1716
Query: 176 --------GTTIKVSVVSPDHV----SDSTVSARISDNSLAPVADFSYPAESSSCLDNSA 223
G+ +S V+P + DS+ +A+ D S +P + P +S +A
Sbjct: 1717 CPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAA 1776
Query: 224 AKHKLQVKPRNQRSSKMRRLSSRAQSESLSDL---TCTPEEEENEEKPLLEVSPEERP-- 278
A K+ KP S+ + S S L+ T P+++ P L + +P
Sbjct: 1777 AFEKVLPKP---ESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLA 1833
Query: 279 SSGQQDVAPDRGPEP---GPP-------------APLPPPGGARARRARLQHSSALTASV 322
+ + ++ P PEP G P A +P P + + + + T S
Sbjct: 1834 PADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESD 1893
Query: 323 EEGGVPG-EDPSSRPATPELAEPESAPTLRVEPPS 356
+ VP E+ S AT + A+ +A + EP S
Sbjct: 1894 SDESVPELEEQDSTQATTQQAQLAAAAEIDEEPVS 1928
Score = 30.8 bits (68), Expect = 6.4
Identities = 55/229 (24%), Positives = 71/229 (31%), Gaps = 44/229 (19%)
Query: 327 VPGEDPSSRPATP-ELAEP--ESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAP 383
+PGE + PAT EL +P E+A S PGP PP PC+P
Sbjct: 1 MPGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPT-------LPP--PCSP 51
Query: 384 ATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTP 443
A P A P T + E P + ++P P
Sbjct: 52 APQ------------QCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEA 99
Query: 444 PVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPA 503
P GPP P A P P+ PS AP + + P
Sbjct: 100 PTFLPNLIGPP---ISPAALALASPM-----------IAPTLKGTPSSSAPLALVALAPH 145
Query: 504 AASEGPAASPPLAAAESPP----VEPGPGSLDAEAAAPERPKAERAEAP 548
+ + A P L SPP E G + AP PK + P
Sbjct: 146 SVQKSSAFPPNLLT--SPPSVAVAESGSVITLSAPIAPSEPKTNLNKVP 192
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 119 bits (298), Expect = 1e-26
Identities = 200/902 (22%), Positives = 300/902 (33%), Gaps = 152/902 (16%)
Query: 42 RKESPSSTGSSTWKQSQTRNEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPES 101
+K P S S T K + R+ + +E+ E ++ S S S
Sbjct: 76 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS--SSS 133
Query: 102 GQDATRPVRVFSQENVCDRIKALQLKIQCN----VKMGPPPPPGGLPAKRGEDAGMSSED 157
R ++ S+ + +R +LK++ N K P P P + ++AG ++
Sbjct: 134 SSSTIRKIKS-SKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVV-----DEAGSGLDN 187
Query: 158 DGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSS 217
+ P+ S T+ K++ P ++ R SL P +D S E+S
Sbjct: 188 GDFKVTTPDTSTTQHNKVSTSPKITTAKP-------INPR---PSLPPNSDTS--KETSL 235
Query: 218 CLDNSAAKHKLQVKPRNQRSSK--MRRLSSRAQSESLSDLTC-------------TPEEE 262
++ + N+++S + +S +++S+ + TP+ E
Sbjct: 236 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 295
Query: 263 ENEEKPLLEVSPEERPSSGQQDV--------------APDRGPEPGP------------P 296
+ P L E P++ ++ AP EP P P
Sbjct: 296 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355
Query: 297 APL----PPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP-ESAPTLR 351
AP P P + A T + P E + P P P E APT
Sbjct: 356 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 415
Query: 352 VEP-PSPPEGPP----NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAI 406
EP P+ P+ P P P K+ P P AP T K AP P PT
Sbjct: 416 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEP----APTTPKEPAPTTT 470
Query: 407 PE-GDTTPPETDPAATSEAPSARDGPERSV-------PKEAEPTPPVLPDEEKGPPGPAP 458
E TTP E P T AP+ P + PKE PT P P PAP
Sbjct: 471 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAP 529
Query: 459 -EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASP---- 513
P++ A T P+ A T P+ P+T P+P PK + P E +P
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPK---EPAPTTPKETAPTTPKKLT 584
Query: 514 ---PLAAAESPPVEPGPGSLDAEA-AAPERPKAERAEAP-PAGAERAAPERKAERGGAEL 568
P A + P +P P + + A PE P E P P + AAP E
Sbjct: 585 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-- 642
Query: 569 RGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPG 628
K + P P + P E A P A L+ KP
Sbjct: 643 --TPKEPAPTTPKEPAP--TTPKETA----------PTTPKGTAPTTLKEPAPTTPKKPA 688
Query: 629 PRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSEDRNPFPVKLR 687
P++LA ++ P A P +EP P +EPAP+ + P L+
Sbjct: 689 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLK 746
Query: 688 STSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGK 747
+ + + + + P K P T P +
Sbjct: 747 EPAPTTPKKPAPKE-------------------LAPTTTKGPTSTTSDKPAPTTPKETAP 787
Query: 748 GKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEK 807
+ P P + K P P T P P P + KEP T K P E
Sbjct: 788 TTPKEPAPTTPKKPAP--------TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Query: 808 SLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERG 867
S P T + P P + T+ + +DK R L++ P P+
Sbjct: 840 SAEP--TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 897
Query: 868 QE 869
+E
Sbjct: 898 KE 899
Score = 112 bits (281), Expect = 1e-24
Identities = 180/808 (22%), Positives = 272/808 (33%), Gaps = 102/808 (12%)
Query: 137 PPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSA 196
PP P G + S P+ P + + + VS + S S+ S+
Sbjct: 72 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 131
Query: 197 RISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLT 256
S +++ + +SS NSAA +LQ K + + + K R + D
Sbjct: 132 SSSSSTIRKI-------KSSK---NSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD-- 179
Query: 257 CTPEEEENEEKPLLEVSPEERPSSGQQDVAPD---RGPEPGPPAPLPPPGGARARRARLQ 313
E + +V+ + ++ V+ +P P P PP ++ L
Sbjct: 180 ---EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 236
Query: 314 HSSALTASVEEGGVPGEDPSS--RPATPELAEPES---------APTLRV-EPPSPPEGP 361
+ T +E + S+ + T E +S APT +V P+P
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296
Query: 362 PNPGPDGGKQDGEAPPAGPCAPATDKAEE-----VVCAPEDVASPFPTAIPEGDTTPPET 416
GP E P P PA+ +E + AP P PT TTP E
Sbjct: 297 TTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 355
Query: 417 DPAATSEAPSARDGPERSVPKE------AEPTPPVLPDEEKGPPGPAP-EPEREAETEPE 469
P T E P + PKE EP P P PAP P++ A T P+
Sbjct: 356 APTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 408
Query: 470 RGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPA-AASEGPAASPPLAAAESPPVEPGPG 528
A T P+ PAP+ P PA A + PA + P A + P EP P
Sbjct: 409 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 468
Query: 529 SL-DAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP---- 583
+ + P+ P ++ P + AP + + P
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 528
Query: 584 -----RPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLP-EPQHAKP---------G 628
+P + P E A P + + A + P P+ P
Sbjct: 529 PTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 587
Query: 629 PRKLAERGPQDSGDRAASPAGPR-------KSPQE------AAAAPGT-REPCPAA-QEP 673
P KLA P+ P +P+E AAAP T +EP P +EP
Sbjct: 588 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 647
Query: 674 APSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTA 733
AP+ + P P + T+ + + A +K + + + L P K P T
Sbjct: 648 APTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELA--PTTTKEPTSTT 704
Query: 734 PALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEP 793
P + P P + K P P P + T +PAP P + P++
Sbjct: 705 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTPKKPAPKELA 762
Query: 794 RTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGAR 851
T K P ++K P P T P +PAP T ++ T + PP +
Sbjct: 763 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPETPPPTTSEVSTP 819
Query: 852 TLKSEP-----GKQAKVPERGQEPVKQA 874
T EP PE EP +A
Sbjct: 820 TTTKEPTTIHKSPDESTPELSAEPTPKA 847
Score = 68.6 bits (166), Expect = 3e-11
Identities = 110/545 (20%), Positives = 174/545 (31%), Gaps = 85/545 (15%)
Query: 354 PPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTP 413
P SPP P P G Q ++ P K + V E++ ++ E +
Sbjct: 69 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEH--SVSENQESS 126
Query: 414 PETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAG 473
+ +++S + S + D +K P P+ E G
Sbjct: 127 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 186
Query: 474 TEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAE 533
++ T P T S +H + SP + A+ P+ P P
Sbjct: 187 NGDFKV-TTPDT----------STTQHNKV------STSPKITTAK--PINPRPSLPPNS 227
Query: 534 AAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKK--FSVSSCRARPRPGVSRPL 591
+ E E E ++ G E + K S+ A+ S+ L
Sbjct: 228 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 287
Query: 592 ERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP-GPRKLAERGPQDSGDRAASPAGP 650
+ + + GP L EP P P + P + ++A
Sbjct: 288 AKPTPKAETTTKGPA---------LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338
Query: 651 RKSPQEAAAAPGT-REPCP-AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKR 708
+P +AP T +EP P +EPAP+ + P P + + +
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT---------------- 382
Query: 709 YSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLL 768
+S PKE P T P + P P + K P P P
Sbjct: 383 ------TTKSAPTTPKE---PAPTTP----------------KKPAPTTPKEPAPTTPKE 417
Query: 769 QSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPW 826
+ T P +PAP P P++ TA K+P ++ P P P +P+P
Sbjct: 418 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP-- 475
Query: 827 ITVTRQKRRGTLDQPPNQEDKPGARTLKSEP-GKQAKVPERGQEPVKQADFVRSKSFLIT 885
T ++ T P +P T KS P + P +EP A + T
Sbjct: 476 -TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP---APTTPKEPAPTT 531
Query: 886 PVKPA 890
P KPA
Sbjct: 532 PKKPA 536
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/417 (21%), Positives = 133/417 (31%), Gaps = 66/417 (15%)
Query: 133 KMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSP--PEMSLLHDVGPGTTIKVSVVSPDHVS 190
K P P P E A +++ P +P P + + P T K++ +P+ ++
Sbjct: 534 KPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 592
Query: 191 DSTVS--ARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQ 248
+T A + LAP P E + A P +++ A
Sbjct: 593 PTTPEKPAPTTPEELAPTT----PEEPTPTTPEEPA-------PTTPKAAAPNTPKEPAP 641
Query: 249 SESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARAR 308
+ TP+E +P+E + + AP EP P P P A
Sbjct: 642 TTPKEPAPTTPKEPA-------PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694
Query: 309 RARLQHSSAL----TASVEEGGVPGEDPSSRPATPELAEPES----APTLRVEPPSPPEG 360
+ +S + +G P P TP+ P + APT EP P
Sbjct: 695 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA--PTT 752
Query: 361 PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV---CAPEDVASPFPTAIPEGDTTPPETD 417
P P P K+ GP + +DK AP P PT + T PET
Sbjct: 753 PKKPAP---KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 809
Query: 418 PAATSEAPSA---------RDGPERSVPK-EAEPTPPVLPDEEKGPPGPAPEPEREAETE 467
P TSE + P+ S P+ AEPTP L + K P
Sbjct: 810 PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------------- 855
Query: 468 PERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVE 524
G T T+P + L+ P + P + A E
Sbjct: 856 ---GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 909
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/408 (20%), Positives = 135/408 (33%), Gaps = 48/408 (11%)
Query: 525 PGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPR 584
P S AE P P + + PP+GA + + K + S
Sbjct: 57 PDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEE 116
Query: 585 PGVSRPLERASGRLPLARSGPV-----WRSEAALDDLQGLPEPQHAK---------PGPR 630
VS E +S + S + ++ AA +LQ + + K P P
Sbjct: 117 HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPP 176
Query: 631 KLAERGP-QDSGD-RAASPAGPRKSPQEAAAAPGTREPCPAAQEPA--PSEDRN------ 680
+ E G D+GD + +P + + +P P P+ P+ D +
Sbjct: 177 VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 236
Query: 681 ----------PFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
+ TS K + +++E + +++ SA+ S + K
Sbjct: 237 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 296
Query: 731 GT-APALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSF-TLPHQPAPPDAGPGERE 788
T PAL + P+ P EP S+ P P ++S T P +PAP
Sbjct: 297 TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 351
Query: 789 PRKEPRTAEKRPLRRGAEKSLPPAATGP------GADGQPAPPWITVTRQKRRGTLDQPP 842
P++ T K P ++ P P A P P T ++ T +P
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411
Query: 843 NQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
K T EP K P P + A K TP +PA
Sbjct: 412 PTTPKEPTPTTPKEPAPTTKEP-APTTPKEPAPTAPKKPAPTTPKEPA 458
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 119 bits (298), Expect = 1e-26
Identities = 200/902 (22%), Positives = 300/902 (33%), Gaps = 152/902 (16%)
Query: 42 RKESPSSTGSSTWKQSQTRNEVIAIESGPVGYDSEDELEESRGTLGSRALSHDSIFIPES 101
+K P S S T K + R+ + +E+ E ++ S S S
Sbjct: 117 KKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSS--SSS 174
Query: 102 GQDATRPVRVFSQENVCDRIKALQLKIQCN----VKMGPPPPPGGLPAKRGEDAGMSSED 157
R ++ S+ + +R +LK++ N K P P P + ++AG ++
Sbjct: 175 SSSTIRKIKS-SKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVV-----DEAGSGLDN 228
Query: 158 DGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSS 217
+ P+ S T+ K++ P ++ R SL P +D S E+S
Sbjct: 229 GDFKVTTPDTSTTQHNKVSTSPKITTAKP-------INPR---PSLPPNSDTS--KETSL 276
Query: 218 CLDNSAAKHKLQVKPRNQRSSK--MRRLSSRAQSESLSDLTC-------------TPEEE 262
++ + N+++S + +S +++S+ + TP+ E
Sbjct: 277 TVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE 336
Query: 263 ENEEKPLLEVSPEERPSSGQQDV--------------APDRGPEPGP------------P 296
+ P L E P++ ++ AP EP P P
Sbjct: 337 TTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396
Query: 297 APL----PPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP-ESAPTLR 351
AP P P + A T + P E + P P P E APT
Sbjct: 397 APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTP 456
Query: 352 VEP-PSPPEGPP----NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAI 406
EP P+ P+ P P P K+ P P AP T K AP P PT
Sbjct: 457 KEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEP----APTTPKEPAPTTT 511
Query: 407 PE-GDTTPPETDPAATSEAPSARDGPERSV-------PKEAEPTPPVLPDEEKGPPGPAP 458
E TTP E P T AP+ P + PKE PT P P PAP
Sbjct: 512 KEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-APTTPKEPAP 570
Query: 459 -EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASP---- 513
P++ A T P+ A T P+ P+T P+P PK + P E +P
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPK---EPAPTTPKETAPTTPKKLT 625
Query: 514 ---PLAAAESPPVEPGPGSLDAEA-AAPERPKAERAEAP-PAGAERAAPERKAERGGAEL 568
P A + P +P P + + A PE P E P P + AAP E
Sbjct: 626 PTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPT-- 683
Query: 569 RGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPG 628
K + P P + P E A P A L+ KP
Sbjct: 684 --TPKEPAPTTPKEPAP--TTPKETA----------PTTPKGTAPTTLKEPAPTTPKKPA 729
Query: 629 PRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSEDRNPFPVKLR 687
P++LA ++ P A P +EP P +EPAP+ + P L+
Sbjct: 730 PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKEPAPTTPKGTAPTTLK 787
Query: 688 STSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGK 747
+ + + + + P K P T P +
Sbjct: 788 EPAPTTPKKPAPKE-------------------LAPTTTKGPTSTTSDKPAPTTPKETAP 828
Query: 748 GKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEK 807
+ P P + K P P T P P P + KEP T K P E
Sbjct: 829 TTPKEPAPTTPKKPAP--------TTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Query: 808 SLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERG 867
S P T + P P + T+ + +DK R L++ P P+
Sbjct: 881 SAEP--TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT 938
Query: 868 QE 869
+E
Sbjct: 939 KE 940
Score = 112 bits (281), Expect = 1e-24
Identities = 180/808 (22%), Positives = 272/808 (33%), Gaps = 102/808 (12%)
Query: 137 PPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSA 196
PP P G + S P+ P + + + VS + S S+ S+
Sbjct: 113 PPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS 172
Query: 197 RISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLT 256
S +++ + +SS NSAA +LQ K + + + K R + D
Sbjct: 173 SSSSSTIRKI-------KSSK---NSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVD-- 220
Query: 257 CTPEEEENEEKPLLEVSPEERPSSGQQDVAPD---RGPEPGPPAPLPPPGGARARRARLQ 313
E + +V+ + ++ V+ +P P P PP ++ L
Sbjct: 221 ---EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 277
Query: 314 HSSALTASVEEGGVPGEDPSS--RPATPELAEPES---------APTLRV-EPPSPPEGP 361
+ T +E + S+ + T E +S APT +V P+P
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337
Query: 362 PNPGPDGGKQDGEAPPAGPCAPATDKAEE-----VVCAPEDVASPFPTAIPEGDTTPPET 416
GP E P P PA+ +E + AP P PT TTP E
Sbjct: 338 TTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP 396
Query: 417 DPAATSEAPSARDGPERSVPKE------AEPTPPVLPDEEKGPPGPAP-EPEREAETEPE 469
P T E P + PKE EP P P PAP P++ A T P+
Sbjct: 397 APTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPK 449
Query: 470 RGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPA-AASEGPAASPPLAAAESPPVEPGPG 528
A T P+ PAP+ P PA A + PA + P A + P EP P
Sbjct: 450 EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT 509
Query: 529 SL-DAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP---- 583
+ + P+ P ++ P + AP + + P
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPA 569
Query: 584 -----RPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLP-EPQHAKP---------G 628
+P + P E A P + + A + P P+ P
Sbjct: 570 PTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTT 628
Query: 629 PRKLAERGPQDSGDRAASPAGPR-------KSPQE------AAAAPGT-REPCPAA-QEP 673
P KLA P+ P +P+E AAAP T +EP P +EP
Sbjct: 629 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEP 688
Query: 674 APSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTA 733
AP+ + P P + T+ + + A +K + + + L P K P T
Sbjct: 689 APTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTPKKPAPKELA--PTTTKEPTSTT 745
Query: 734 PALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEP 793
P + P P + K P P P + T +PAP P + P++
Sbjct: 746 CDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP--TTPKKPAPKELA 803
Query: 794 RTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGAR 851
T K P ++K P P T P +PAP T ++ T + PP +
Sbjct: 804 PTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TTPKKPAPTTPETPPPTTSEVSTP 860
Query: 852 TLKSEP-----GKQAKVPERGQEPVKQA 874
T EP PE EP +A
Sbjct: 861 TTTKEPTTIHKSPDESTPELSAEPTPKA 888
Score = 68.6 bits (166), Expect = 3e-11
Identities = 110/545 (20%), Positives = 174/545 (31%), Gaps = 85/545 (15%)
Query: 354 PPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTP 413
P SPP P P G Q ++ P K + V E++ ++ E +
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEH--SVSENQESS 167
Query: 414 PETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAG 473
+ +++S + S + D +K P P+ E G
Sbjct: 168 SSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLD 227
Query: 474 TEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAE 533
++ T P T S +H + SP + A+ P+ P P
Sbjct: 228 NGDFKV-TTPDT----------STTQHNKV------STSPKITTAK--PINPRPSLPPNS 268
Query: 534 AAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKK--FSVSSCRARPRPGVSRPL 591
+ E E E ++ G E + K S+ A+ S+ L
Sbjct: 269 DTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVL 328
Query: 592 ERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP-GPRKLAERGPQDSGDRAASPAGP 650
+ + + GP L EP P P + P + ++A
Sbjct: 329 AKPTPKAETTTKGPA---------LTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379
Query: 651 RKSPQEAAAAPGT-REPCP-AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKR 708
+P +AP T +EP P +EPAP+ + P P + + +
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPT---------------- 423
Query: 709 YSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLL 768
+S PKE P T P + P P + K P P P
Sbjct: 424 ------TTKSAPTTPKE---PAPTTP----------------KKPAPTTPKEPAPTTPKE 458
Query: 769 QSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPW 826
+ T P +PAP P P++ TA K+P ++ P P P +P+P
Sbjct: 459 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSP-- 516
Query: 827 ITVTRQKRRGTLDQPPNQEDKPGARTLKSEP-GKQAKVPERGQEPVKQADFVRSKSFLIT 885
T ++ T P +P T KS P + P +EP A + T
Sbjct: 517 -TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP---APTTPKEPAPTT 572
Query: 886 PVKPA 890
P KPA
Sbjct: 573 PKKPA 577
Score = 58.9 bits (141), Expect = 2e-08
Identities = 90/417 (21%), Positives = 133/417 (31%), Gaps = 66/417 (15%)
Query: 133 KMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSP--PEMSLLHDVGPGTTIKVSVVSPDHVS 190
K P P P E A +++ P +P P + + P T K++ +P+ ++
Sbjct: 575 KPAPTTPKEPAPTTPKEPAPTTTKKPA-PTTPKEPAPTTPKETAPTTPKKLTPTTPEKLA 633
Query: 191 DSTVS--ARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQ 248
+T A + LAP P E + A P +++ A
Sbjct: 634 PTTPEKPAPTTPEELAPTT----PEEPTPTTPEEPA-------PTTPKAAAPNTPKEPAP 682
Query: 249 SESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARAR 308
+ TP+E +P+E + + AP EP P P P A
Sbjct: 683 TTPKEPAPTTPKEPA-------PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735
Query: 309 RARLQHSSAL----TASVEEGGVPGEDPSSRPATPELAEPES----APTLRVEPPSPPEG 360
+ +S + +G P P TP+ P + APT EP P
Sbjct: 736 TTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA--PTT 793
Query: 361 PPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV---CAPEDVASPFPTAIPEGDTTPPETD 417
P P P K+ GP + +DK AP P PT + T PET
Sbjct: 794 PKKPAP---KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP 850
Query: 418 PAATSEAPSA---------RDGPERSVPK-EAEPTPPVLPDEEKGPPGPAPEPEREAETE 467
P TSE + P+ S P+ AEPTP L + K P
Sbjct: 851 PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEP-------------- 896
Query: 468 PERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVE 524
G T T+P + L+ P + P + A E
Sbjct: 897 ---GVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTE 950
Score = 45.4 bits (106), Expect = 2e-04
Identities = 85/408 (20%), Positives = 135/408 (33%), Gaps = 48/408 (11%)
Query: 525 PGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPR 584
P S AE P P + + PP+GA + + K + S
Sbjct: 98 PDYESFCAEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEE 157
Query: 585 PGVSRPLERASGRLPLARSGPV-----WRSEAALDDLQGLPEPQHAK---------PGPR 630
VS E +S + S + ++ AA +LQ + + K P P
Sbjct: 158 HSVSENQESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPP 217
Query: 631 KLAERGP-QDSGD-RAASPAGPRKSPQEAAAAPGTREPCPAAQEPA--PSEDRN------ 680
+ E G D+GD + +P + + +P P P+ P+ D +
Sbjct: 218 VVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLT 277
Query: 681 ----------PFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
+ TS K + +++E + +++ SA+ S + K
Sbjct: 278 VNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAET 337
Query: 731 GT-APALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSF-TLPHQPAPPDAGPGERE 788
T PAL + P+ P EP S+ P P ++S T P +PAP
Sbjct: 338 TTKGPALTTPKEPT-----PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTT 392
Query: 789 PRKEPRTAEKRPLRRGAEKSLPPAATGP------GADGQPAPPWITVTRQKRRGTLDQPP 842
P++ T K P ++ P P A P P T ++ T +P
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452
Query: 843 NQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
K T EP K P P + A K TP +PA
Sbjct: 453 PTTPKEPTPTTPKEPAPTTKEP-APTTPKEPAPTAPKKPAPTTPKEPA 499
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 118 bits (295), Expect = 3e-26
Identities = 151/611 (24%), Positives = 204/611 (33%), Gaps = 88/611 (14%)
Query: 283 QDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELA 342
++ AP EP P P P A SA T E + P+ P TP+
Sbjct: 260 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPK-- 315
Query: 343 EPESAPTLRVEP-PSPPEGPP----NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPED 397
E APT EP P+ P+ P P P K+ P P AP T K AP
Sbjct: 316 --EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEP----APTT 368
Query: 398 VASPFPTAIPE-GDTTPPETDPAATSEAPSARDGPERSV-------PKEAEPTPPVLPDE 449
P PT E TTP E P T AP+ P + PKE PT P
Sbjct: 369 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-A 427
Query: 450 EKGPPGPAP-EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEG 508
P PAP P++ A T P+ A T P+ P+T P+P PK + P E
Sbjct: 428 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPK---EPAPTTPKET 482
Query: 509 PAASP-------PLAAAESPPVEPGPGSLDAEA-AAPERPKAERAEAP-PAGAERAAPER 559
+P P A + P +P P + + A PE P E P P + AAP
Sbjct: 483 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 542
Query: 560 KAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619
E K + P P + P E A P A L+
Sbjct: 543 PKEPAPT----TPKEPAPTTPKEPAP--TTPKETA----------PTTPKGTAPTTLKEP 586
Query: 620 PEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSED 678
KP P++LA ++ P A P +EP P +EPAP+
Sbjct: 587 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKEPAPTTP 644
Query: 679 RNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRG 738
+ P L+ + + + + + P K P T
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKE-------------------LAPTTTKGPTSTTSDKPA 685
Query: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEK 798
P + + P P + K P P T P P P + KEP T K
Sbjct: 686 PTTPKETAPTTPKEPAPTTPKKPAP--------TTPETPPPTTSEVSTPTTTKEPTTIHK 737
Query: 799 RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPG 858
P E S P T + P P + T+ + +DK R L++ P
Sbjct: 738 SPDESTPELSAEP--TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795
Query: 859 KQAKVPERGQE 869
P+ +E
Sbjct: 796 TTTAAPKMTKE 806
Score = 109 bits (272), Expect = 1e-23
Identities = 152/650 (23%), Positives = 219/650 (33%), Gaps = 84/650 (12%)
Query: 292 EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSS--RPATPELAEPES--- 346
+P P P PP ++ L + T +E + S+ + T E +S
Sbjct: 122 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 181
Query: 347 ------APTLRV-EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEE-----VVCA 394
APT +V P+P GP E P P PA+ +E + A
Sbjct: 182 TSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 395 PEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKE------AEPTPPVLPD 448
P P PT TTP E P T E P + PKE EP P
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKS 293
Query: 449 EEKGPPGPAP-EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPA-AAS 506
P PAP P++ A T P+ A T P+ PAP+ P PA A
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 353
Query: 507 EGPAASPPLAAAESPPVEPGPGSL-DAEAAAPERPKAERAEAPPAGAERAAPERKAERGG 565
+ PA + P A + P EP P + + P+ P ++ P + AP
Sbjct: 354 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413
Query: 566 AELRGAKKFSVSSCRARP---------RPGVSRPLERASGRLPLARSGPVWRSEAALDDL 616
+ + P +P + P E A P + + A
Sbjct: 414 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPK 472
Query: 617 QGLP-EPQHAKP---------GPRKLAERGPQDSGDRAASPAGPR-------KSPQE--- 656
+ P P+ P P KLA P+ P +P+E
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532
Query: 657 ---AAAAPGT-REPCPAA-QEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSA 711
AAAP T +EP P +EPAP+ + P P + T+ + + A +K +
Sbjct: 533 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTP 591
Query: 712 EVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSF 771
+ + L P K P T P + P P + K P P P +
Sbjct: 592 KKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 649
Query: 772 TLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITV 829
T +PAP P + P++ T K P ++K P P T P +PAP T
Sbjct: 650 TTLKEPAP--TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TT 704
Query: 830 TRQKRRGTLDQPPNQEDKPGARTLKSEP-----GKQAKVPERGQEPVKQA 874
++ T + PP + T EP PE EP +A
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Score = 103 bits (258), Expect = 6e-22
Identities = 140/543 (25%), Positives = 198/543 (36%), Gaps = 100/543 (18%)
Query: 258 TPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSA 317
TP+E K +P+E + + AP EP P P P
Sbjct: 329 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP---------------- 372
Query: 318 LTASVEEGGVPGEDPSSRPATPELAEP---ESAPTLRVEP-----PSPPEGPPNPGPDGG 369
P P TP+ P +SAPT EP S P P P P
Sbjct: 373 ---------APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423
Query: 370 KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSE-APSAR 428
K+ P P AP T K AP P P TTP E P T + AP+
Sbjct: 424 KEPAPTTPKEP-APTTPKKP----APTTPKEPAP-------TTPKEPAPTTTKKPAPTTP 471
Query: 429 DGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPA 488
P + PKE PT P +K P PE+ A T PE+ A T PE + P+T
Sbjct: 472 KEPAPTTPKETAPTTP-----KKLTP---TTPEKLAPTTPEKPAPTTPEELA--PTTPEE 521
Query: 489 PSPPAPKSCLKHRPAAAS----EGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAER 544
P+P P+ P AA+ + PA + P A + P EP P + + AP PK
Sbjct: 522 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKG-- 577
Query: 545 AEAPPAGAERAAPERKAERGGAELR-GAKKFSVSSCRARPRPGVSRPLERASGRLPLARS 603
P + AP + EL K S+ +P P + + + P
Sbjct: 578 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP---- 631
Query: 604 GPVWRSEAALDDLQG-----LPEPQHA---KPGPRKLA---ERGPQDSGDRAASPAGPRK 652
P E A +G L EP KP P++LA +GP + +P P++
Sbjct: 632 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 691
Query: 653 ----SPQEAAAAPGTREPCPAAQE-PAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVK 707
+P+E A ++P P E P P+ P + + K D ++ E+
Sbjct: 692 TAPTTPKEPAPTT-PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL---- 746
Query: 708 RYSAEVRLERSLTVLPKE-----EKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPL 762
SAE ++L PKE K P T P + T + PE ++ P +
Sbjct: 747 --SAE-PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 803
Query: 763 PRK 765
++
Sbjct: 804 TKE 806
Score = 93.6 bits (231), Expect = 8e-19
Identities = 152/614 (24%), Positives = 210/614 (34%), Gaps = 120/614 (19%)
Query: 247 AQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPP----- 301
A + + S T E K +P+E + + AP EP P P P
Sbjct: 404 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463
Query: 302 ----------PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLR 351
P + LT + E P P TPE E APT
Sbjct: 464 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE----ELAPTTP 519
Query: 352 VEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPE-GD 410
EP P P P P K P P AP T K AP P PT E
Sbjct: 520 EEP--TPTTPEEPAPTTPKAAAPNTPKEP-APTTPKEP----APTTPKEPAPTTPKETAP 572
Query: 411 TTPPETDPAATSE-APSARDGPERSVPKEAEPTPPVLPDE-------EKGPPGPAP-EPE 461
TTP T P E AP+ P++ PKE PT P P G AP P+
Sbjct: 573 TTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 629
Query: 462 REAETEPERGAGTEPERIGTEPSTAPAPSP-----PAPK----SCLKHRPAAASEGPAAS 512
A T P+ A T P+ GT P+T P+P PAPK + K + S+ PA +
Sbjct: 630 EPAPTTPKEPAPTTPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEA-PPAGAERAAPERKAERGGAELRGA 571
P A + P EP P P++P E PP +E + P E + +
Sbjct: 688 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKS 738
Query: 572 KKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRK 631
S A P P +A P P ++ AA +P+ K
Sbjct: 739 PDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAA-------TKPEMTTTAKDK 784
Query: 632 LAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQ----EPAPSEDRNPFPV-KL 686
ER + + + + A P+ + + A T E A ++D PF + L
Sbjct: 785 TTERDLRTTPE--TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 842
Query: 687 RSTSLSLKY----RDGASQEVKGVKRYSAEV--RLERSLTVLPKEEKCPLGTAPALRGTR 740
++T+L+ K + + E+ +A+ R S PK +K + +
Sbjct: 843 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK-------PTKAPK 895
Query: 741 APSDQGKGKARPPEPLSSKPPLPRK----------------PLLQSFTLPHQ-------- 776
P+ K K P P PRK +LQ+ T P+Q
Sbjct: 896 KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 955
Query: 777 --PAPPDAGPGERE 788
P DAG E E
Sbjct: 956 VNPKSEDAGGAEGE 969
Score = 64.3 bits (155), Expect = 5e-10
Identities = 66/279 (23%), Positives = 103/279 (36%), Gaps = 35/279 (12%)
Query: 625 AKPGPR-KLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFP 683
AKP P+ + +GP + + +P P+ + A+ P +EP P + AP+ + P P
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPK---EPASTTP--KEPTPTTIKSAPTTPKEPAP 249
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA-- 741
+S + K A + PKE PA T++
Sbjct: 250 TTTKSAPTTPKE--------------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 295
Query: 742 --PSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKR 799
P + + P P + K P P P + T P +PAP P P++ TA K+
Sbjct: 296 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 355
Query: 800 PLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEP 857
P ++ P P P +P+P T ++ T P +P T KS P
Sbjct: 356 PAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 412
Query: 858 GKQAKV-PERGQEPV-----KQADFVRSKSFLITPVKPA 890
+ P +EP + A K TP +PA
Sbjct: 413 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 451
Score = 59.3 bits (142), Expect = 2e-08
Identities = 89/408 (21%), Positives = 127/408 (31%), Gaps = 40/408 (9%)
Query: 510 AASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELR 569
+ SP + A+ P+ P P + E E E ++ G E
Sbjct: 113 STSPKITTAK--PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 170
Query: 570 GAKKF--SVSSCRARPRPGVSRPLERASGRLPLARSGPVWRS---------EAALDDLQG 618
+ K S+ A+ S+ L + + + GP + +
Sbjct: 171 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 230
Query: 619 LPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSE 677
P P K P E P + +P P A T+EP P +EPAP+
Sbjct: 231 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------APTTTKEPAPTTPKEPAPTT 282
Query: 678 DRNPFPVKLRSTSLSLKYRDGASQEVKG--VKRYSAEVRLERSLTVLPKEE----KCPLG 731
+ P P +S + K + + + A + PKE K P
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 732 TAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP---DAGPGERE 788
T P AP + P P + K P P S T P +PAP A +E
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 789 PR----KEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPP 842
P K T K P ++ P P P +PAP T ++ T +P
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPA 459
Query: 843 NQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
K A T EP P K K TP KPA
Sbjct: 460 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 507
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 118 bits (295), Expect = 3e-26
Identities = 151/611 (24%), Positives = 204/611 (33%), Gaps = 88/611 (14%)
Query: 283 QDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELA 342
++ AP EP P P P A SA T E + P+ P TP+
Sbjct: 301 KEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA--PTTPK-- 356
Query: 343 EPESAPTLRVEP-PSPPEGPP----NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPED 397
E APT EP P+ P+ P P P K+ P P AP T K AP
Sbjct: 357 --EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKP-APTTPKEP----APTT 409
Query: 398 VASPFPTAIPE-GDTTPPETDPAATSEAPSARDGPERSV-------PKEAEPTPPVLPDE 449
P PT E TTP E P T AP+ P + PKE PT P
Sbjct: 410 PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEP-A 468
Query: 450 EKGPPGPAP-EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEG 508
P PAP P++ A T P+ A T P+ P+T P+P PK + P E
Sbjct: 469 PTTPKEPAPTTPKKPAPTTPKEPAPTTPKE--PAPTTTKKPAPTTPK---EPAPTTPKET 523
Query: 509 PAASP-------PLAAAESPPVEPGPGSLDAEA-AAPERPKAERAEAP-PAGAERAAPER 559
+P P A + P +P P + + A PE P E P P + AAP
Sbjct: 524 APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNT 583
Query: 560 KAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619
E K + P P + P E A P A L+
Sbjct: 584 PKEPAPT----TPKEPAPTTPKEPAP--TTPKETA----------PTTPKGTAPTTLKEP 627
Query: 620 PEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSED 678
KP P++LA ++ P A P +EP P +EPAP+
Sbjct: 628 APTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP--KEPAPTTPKEPAPTTP 685
Query: 679 RNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRG 738
+ P L+ + + + + + P K P T
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKE-------------------LAPTTTKGPTSTTSDKPA 726
Query: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEK 798
P + + P P + K P P T P P P + KEP T K
Sbjct: 727 PTTPKETAPTTPKEPAPTTPKKPAP--------TTPETPPPTTSEVSTPTTTKEPTTIHK 778
Query: 799 RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPG 858
P E S P T + P P + T+ + +DK R L++ P
Sbjct: 779 SPDESTPELSAEP--TPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836
Query: 859 KQAKVPERGQE 869
P+ +E
Sbjct: 837 TTTAAPKMTKE 847
Score = 109 bits (272), Expect = 1e-23
Identities = 152/650 (23%), Positives = 219/650 (33%), Gaps = 84/650 (12%)
Query: 292 EPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSS--RPATPELAEPES--- 346
+P P P PP ++ L + T +E + S+ + T E +S
Sbjct: 163 KPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEK 222
Query: 347 ------APTLRV-EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEE-----VVCA 394
APT +V P+P GP E P P PA+ +E + A
Sbjct: 223 TSAKDLAPTSKVLAKPTPKAETTTKGP-ALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 395 PEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKE------AEPTPPVLPD 448
P P PT TTP E P T E P + PKE EP P
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKE-------PAPTTPKEPAPTTTKEPAPTTTKS 334
Query: 449 EEKGPPGPAP-EPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPA-AAS 506
P PAP P++ A T P+ A T P+ PAP+ P PA A
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAP 394
Query: 507 EGPAASPPLAAAESPPVEPGPGSL-DAEAAAPERPKAERAEAPPAGAERAAPERKAERGG 565
+ PA + P A + P EP P + + P+ P ++ P + AP
Sbjct: 395 KKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454
Query: 566 AELRGAKKFSVSSCRARP---------RPGVSRPLERASGRLPLARSGPVWRSEAALDDL 616
+ + P +P + P E A P + + A
Sbjct: 455 TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAP-TTPKEPAPTTTKKPAPTTPK 513
Query: 617 QGLP-EPQHAKP---------GPRKLAERGPQDSGDRAASPAGPR-------KSPQE--- 656
+ P P+ P P KLA P+ P +P+E
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573
Query: 657 ---AAAAPGT-REPCPAA-QEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSA 711
AAAP T +EP P +EPAP+ + P P + T+ + + A +K +
Sbjct: 574 TTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP-KGTAPTTLKEPAPTTP 632
Query: 712 EVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSF 771
+ + L P K P T P + P P + K P P P +
Sbjct: 633 KKPAPKELA--PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAP 690
Query: 772 TLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITV 829
T +PAP P + P++ T K P ++K P P T P +PAP T
Sbjct: 691 TTLKEPAP--TTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAP---TT 745
Query: 830 TRQKRRGTLDQPPNQEDKPGARTLKSEP-----GKQAKVPERGQEPVKQA 874
++ T + PP + T EP PE EP +A
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795
Score = 103 bits (258), Expect = 6e-22
Identities = 140/543 (25%), Positives = 198/543 (36%), Gaps = 100/543 (18%)
Query: 258 TPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSA 317
TP+E K +P+E + + AP EP P P P
Sbjct: 370 TPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEP---------------- 413
Query: 318 LTASVEEGGVPGEDPSSRPATPELAEP---ESAPTLRVEP-----PSPPEGPPNPGPDGG 369
P P TP+ P +SAPT EP S P P P P
Sbjct: 414 ---------APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464
Query: 370 KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSE-APSAR 428
K+ P P AP T K AP P P TTP E P T + AP+
Sbjct: 465 KEPAPTTPKEP-APTTPKKP----APTTPKEPAP-------TTPKEPAPTTTKKPAPTTP 512
Query: 429 DGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPA 488
P + PKE PT P +K P PE+ A T PE+ A T PE + P+T
Sbjct: 513 KEPAPTTPKETAPTTP-----KKLTP---TTPEKLAPTTPEKPAPTTPEELA--PTTPEE 562
Query: 489 PSPPAPKSCLKHRPAAAS----EGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAER 544
P+P P+ P AA+ + PA + P A + P EP P + + AP PK
Sbjct: 563 PTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKG-- 618
Query: 545 AEAPPAGAERAAPERKAERGGAELR-GAKKFSVSSCRARPRPGVSRPLERASGRLPLARS 603
P + AP + EL K S+ +P P + + + P
Sbjct: 619 --TAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP---- 672
Query: 604 GPVWRSEAALDDLQG-----LPEPQHA---KPGPRKLA---ERGPQDSGDRAASPAGPRK 652
P E A +G L EP KP P++LA +GP + +P P++
Sbjct: 673 APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKE 732
Query: 653 ----SPQEAAAAPGTREPCPAAQE-PAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVK 707
+P+E A ++P P E P P+ P + + K D ++ E+
Sbjct: 733 TAPTTPKEPAPTT-PKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL---- 787
Query: 708 RYSAEVRLERSLTVLPKE-----EKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPL 762
SAE ++L PKE K P T P + T + PE ++ P +
Sbjct: 788 --SAE-PTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKM 844
Query: 763 PRK 765
++
Sbjct: 845 TKE 847
Score = 93.6 bits (231), Expect = 8e-19
Identities = 152/614 (24%), Positives = 210/614 (34%), Gaps = 120/614 (19%)
Query: 247 AQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPP----- 301
A + + S T E K +P+E + + AP EP P P P
Sbjct: 445 APTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504
Query: 302 ----------PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLR 351
P + LT + E P P TPE E APT
Sbjct: 505 KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE----ELAPTTP 560
Query: 352 VEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPE-GD 410
EP P P P P K P P AP T K AP P PT E
Sbjct: 561 EEP--TPTTPEEPAPTTPKAAAPNTPKEP-APTTPKEP----APTTPKEPAPTTPKETAP 613
Query: 411 TTPPETDPAATSE-APSARDGPERSVPKEAEPTPPVLPDE-------EKGPPGPAP-EPE 461
TTP T P E AP+ P++ PKE PT P P G AP P+
Sbjct: 614 TTPKGTAPTTLKEPAPTT---PKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPK 670
Query: 462 REAETEPERGAGTEPERIGTEPSTAPAPSP-----PAPK----SCLKHRPAAASEGPAAS 512
A T P+ A T P+ GT P+T P+P PAPK + K + S+ PA +
Sbjct: 671 EPAPTTPKEPAPTTPK--GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEA-PPAGAERAAPERKAERGGAELRGA 571
P A + P EP P P++P E PP +E + P E + +
Sbjct: 729 TPKETAPTTPKEPAP-------TTPKKPAPTTPETPPPTTSEVSTPTTTKE--PTTIHKS 779
Query: 572 KKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRK 631
S A P P +A P P ++ AA +P+ K
Sbjct: 780 PDESTPELSAEPTP-------KALENSPKEPGVPTTKTPAA-------TKPEMTTTAKDK 825
Query: 632 LAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQ----EPAPSEDRNPFPV-KL 686
ER + + + + A P+ + + A T E A ++D PF + L
Sbjct: 826 TTERDLRTTPE--TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTL 883
Query: 687 RSTSLSLKY----RDGASQEVKGVKRYSAEV--RLERSLTVLPKEEKCPLGTAPALRGTR 740
++T+L+ K + + E+ +A+ R S PK +K + +
Sbjct: 884 KTTTLAPKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQK-------PTKAPK 936
Query: 741 APSDQGKGKARPPEPLSSKPPLPRK----------------PLLQSFTLPHQ-------- 776
P+ K K P P PRK +LQ+ T P+Q
Sbjct: 937 KPTSTKKPKTMPRVRKPKTTPTPRKMTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVE 996
Query: 777 --PAPPDAGPGERE 788
P DAG E E
Sbjct: 997 VNPKSEDAGGAEGE 1010
Score = 64.3 bits (155), Expect = 5e-10
Identities = 66/279 (23%), Positives = 103/279 (36%), Gaps = 35/279 (12%)
Query: 625 AKPGPR-KLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFP 683
AKP P+ + +GP + + +P P+ + A+ P +EP P + AP+ + P P
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPK---EPASTTP--KEPTPTTIKSAPTTPKEPAP 290
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA-- 741
+S + K A + PKE PA T++
Sbjct: 291 TTTKSAPTTPKE--------------PAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAP 336
Query: 742 --PSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKR 799
P + + P P + K P P P + T P +PAP P P++ TA K+
Sbjct: 337 TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKK 396
Query: 800 PLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEP 857
P ++ P P P +P+P T ++ T P +P T KS P
Sbjct: 397 PAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTTKSAP 453
Query: 858 GKQAKV-PERGQEPV-----KQADFVRSKSFLITPVKPA 890
+ P +EP + A K TP +PA
Sbjct: 454 TTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA 492
Score = 59.3 bits (142), Expect = 2e-08
Identities = 89/408 (21%), Positives = 127/408 (31%), Gaps = 40/408 (9%)
Query: 510 AASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELR 569
+ SP + A+ P+ P P + E E E ++ G E
Sbjct: 154 STSPKITTAK--PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKT 211
Query: 570 GAKKF--SVSSCRARPRPGVSRPLERASGRLPLARSGPVWRS---------EAALDDLQG 618
+ K S+ A+ S+ L + + + GP + +
Sbjct: 212 TSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPK 271
Query: 619 LPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAA-QEPAPSE 677
P P K P E P + +P P A T+EP P +EPAP+
Sbjct: 272 EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEP--------APTTTKEPAPTTPKEPAPTT 323
Query: 678 DRNPFPVKLRSTSLSLKYRDGASQEVKG--VKRYSAEVRLERSLTVLPKEE----KCPLG 731
+ P P +S + K + + + A + PKE K P
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 732 TAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP---DAGPGERE 788
T P AP + P P + K P P S T P +PAP A +E
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 789 PR----KEPRTAEKRPLRRGAEKSLP--PAATGPGADGQPAPPWITVTRQKRRGTLDQPP 842
P K T K P ++ P P P +PAP T ++ T +P
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAP---TTPKEPAPTTPKEPA 500
Query: 843 NQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
K A T EP P K K TP KPA
Sbjct: 501 PTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPA 548
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 99.0 bits (245), Expect = 2e-20
Identities = 160/641 (24%), Positives = 222/641 (34%), Gaps = 83/641 (12%)
Query: 230 VKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDR 289
V+ R R ++ + ESLS+ + EEEE E+ E ++ S + + D
Sbjct: 1019 VRRRPARPLELDSGGEEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDDRDESENDD 1078
Query: 290 GPEPGPPAPLPPPGGA-RARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAP 348
A G + + S A S E E SS ++P +E E
Sbjct: 1079 EDTALSEASEKDEGDSDEEETVSIVTSKAEATSSSESSESSEFESSSESSPSSSEDEEEV 1138
Query: 349 TLRVEPPSPPE-------GPPNPGPDGGKQDGEAPPAGPCAPATDKA---EEVVCAPEDV 398
R E E + GP+ +QDGE P APA D EEV E V
Sbjct: 1139 VAREEEEEEEEEEMVAEESMASAGPEDFEQDGEEAALAPGAPAVDSLGMEEEVDIETEAV 1198
Query: 399 ASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAP 458
A ++ + P + A S P G + P PP E + P P
Sbjct: 1199 APEERPSMLDEPPLPVGVEEPADSREPPEEPGLSQEGAMLLSPEPPAKEVEARPPLSPER 1258
Query: 459 EPEREAETEPERGAGTEPERIGTEP--STAPAPSPPAPKSCLKHRPAAASEGPAASPPLA 516
PE + E EP EP + P P P PP P S + P+ P
Sbjct: 1259 APEHDLEVEP------EPPMMLPLPLQPPLPPPRPPRPPSPPPEPETTDASHPSVPPEPL 1312
Query: 517 AAESPPVEPG-PGSLDAEAAAPERPKAERAEAPPAGAERA----------------APER 559
A + PP PG GSL + P E P +G AP
Sbjct: 1313 AEDHPPHTPGLCGSLAKSQSTETVPATPGGEPPLSGGSSGLSLSSPQVPGSPFSYPAPSP 1372
Query: 560 KAERGGAELRGAKKFSVSSCRARPRPGVSRPL-ERASGRLPLARSGPVWRSEAALDDLQG 618
GG + FS + + P + P+ +GR RSGP+ S L+ G
Sbjct: 1373 SLSSGGLPRTPGRDFSFTPTFSEPSGPLLLPVCPLPTGRRD-ERSGPL-ASPVLLE--TG 1428
Query: 619 LPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSED 678
LP P P P LA + RA +P P P P A P P +
Sbjct: 1429 LPLPL-PLPLPLPLALPAVLRAQARAPTPLPPLL-------------PAPLASCPPPMKR 1474
Query: 679 RNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRG 738
+ P + + LSL DG + R A L R L +LP + + P+ +
Sbjct: 1475 KPGRPRRSPPSMLSL---DGP------LVRPPAGAALGRELLLLPGQPQTPVFPSTHDPR 1525
Query: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFT----------LPHQPAPPDAGPGERE 788
T + G PP PL +PP P P T P + PP GP R+
Sbjct: 1526 TVTLDFRNAGIPAPPPPLPPQPPPPPPPPPVEPTKLPFKELDNQWPSEAIPP--GPRGRD 1583
Query: 789 PRKE-------PRTAEKRPLRRGAEKSLPPAATGPGADGQP 822
E R +RP ++ E +PPA + + QP
Sbjct: 1584 EVTEEYMELAKSRGPWRRPPKKRHEDLVPPAGSPELSPPQP 1624
Score = 56.6 bits (135), Expect = 1e-07
Identities = 87/358 (24%), Positives = 114/358 (31%), Gaps = 85/358 (23%)
Query: 244 SSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPG 303
SSR S L D++ TP + +E++ L + P PEPGPP P
Sbjct: 561 SSRPSSTGLEDISPTPLPDSDEDEEL------------DLGLGPRPPPEPGPP----DPA 604
Query: 304 GARARRARL------------------QHSSALTASVEEGGVPGEDPSSR---------P 336
G ++ A + Q SS + + +P +S P
Sbjct: 605 GLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEISDDEMPSAPITSADCPKPMVVTP 664
Query: 337 ATPELAEPES-APTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAP 395
+A P APTL + PP P PP P P PP P P
Sbjct: 665 GAAAVAAPSVLAPTLPLPPP--PGFPPLPPP---------PPPPPPQPGF---------- 703
Query: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
P P +P PP PA T P P P PP+LP PPG
Sbjct: 704 -----PMPPPLPPPPPPPPPAHPAVTVPPPPLPAPP-------GVPPPPILPPLPPFPPG 751
Query: 456 PAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPL 515
P + + G P + + T + + P A+ AAS L
Sbjct: 752 LFPVMQVDMSHVLGGQWGGMP--MSFQMQTQVLSRLMTGQGACPYPPFMAAAAAAASAGL 809
Query: 516 AAAESPPVEPGPGSLDAEAAA-----PERPKAERAEAPPAGAERAAPERKAERGGAEL 568
PP GP SL P PK + + PP R KA G L
Sbjct: 810 QFVNLPPYR-GPFSLSNSGPGRGQHWPPLPKFDPSVPPPGYMPRQEDPHKATVDGVLL 866
Score = 51.2 bits (121), Expect = 5e-06
Identities = 124/515 (24%), Positives = 152/515 (29%), Gaps = 143/515 (27%)
Query: 325 GGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPA 384
G V G SS P P A+P+ + T PP P + P PG
Sbjct: 355 GAVGGTGGSSGP--PFKAQPQDSATFAHTPP-PAQATPAPGF------------------ 393
Query: 385 TDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPP 444
+ SP+ T P PP +P AT+ A ARD E P PP
Sbjct: 394 -----------KSAFSPYQT--PVAHFPPPPEEPTATA-AFGARDSGEF----RRAPAPP 435
Query: 445 VLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSC-LKHRPA 503
LP PA +E +P T P P PP S L RP
Sbjct: 436 PLP--------PAEPLAKE------------------KPGTPPGPPPPDTNSMELGGRPT 469
Query: 504 AA-SEGPAASPPLAAAESPPVEPGP--GSLDAEAAA---PERPKAERAEAPPAGAERAAP 557
S P SP ES P P SLD+ +R K P + E
Sbjct: 470 FGWSPEPCDSPGTPTLESSPAGPEKPHDSLDSRIEMLLKEQRTKLLFLREPDSDTELQME 529
Query: 558 ERKAERGGAELRGAKKFSVSSCRA--RPRPGVSRPLERASGRLPLARSGPVWRSEAALDD 615
++L F +S P P SRP S L+D
Sbjct: 530 GSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRP------------------SSTGLED 571
Query: 616 LQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAP 675
+ P P D + GPR P+ PG +P + A
Sbjct: 572 ISPTPLPD--------------SDEDEELDLGLGPRPPPE-----PGPPDPAGLLSQTAE 612
Query: 676 SE-----DRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
DR P K+ S G E+ + SA + + PK P+
Sbjct: 613 VALDLVGDRTPTSEKMDEGQQS----SGEDMEISDDEMPSAPI----TSADCPK----PM 660
Query: 731 GTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPR 790
P APS PP P PPLP P PP PG P
Sbjct: 661 VVTPGAAAVAAPSVLAPTLPLPPPP--GFPPLPPPP-----------PPPPPQPGFPMPP 707
Query: 791 KEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPP 825
P P A PP P G P PP
Sbjct: 708 PLPPPPPPPPPAHPAVTVPPPPL--PAPPGVPPPP 740
Score = 45.4 bits (106), Expect = 2e-04
Identities = 79/320 (24%), Positives = 109/320 (34%), Gaps = 45/320 (14%)
Query: 274 PEERPSSGQQDVAPDRGPEPGPPAPLP-PPGGARARRARLQHSSAL---TASVEEGGVP- 328
P E P++ A D G PAP P PP A+ T S+E GG P
Sbjct: 410 PPEEPTATAAFGARDSGEFRRAPAPPPLPPAEPLAKEKPGTPPGPPPPDTNSMELGGRPT 469
Query: 329 ---GEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPAT 385
+P P TP L ES+P P P + + ++ P +
Sbjct: 470 FGWSPEPCDSPGTPTL---ESSPA----GPEKPHDSLDSRIEMLLKEQRTKLLFLREPDS 522
Query: 386 DKAEEVVCAPEDVAS-------PFPTAIPEG--DTTPPETDPAATS-EAPSARDGPERSV 435
D ++ +P +S PF T G TPP + P++T E S P+
Sbjct: 523 DTELQMEGSPISSSSSQLSPLAPFGTNSQPGFRGPTPPSSRPSSTGLEDISPTPLPDSDE 582
Query: 436 PKEAEPTPPVLPDEEKGPPGPAP----------------EPEREAETEPERGAGTEPERI 479
+E + P E GPP PA P E E ++ +G + E
Sbjct: 583 DEELDLGLGPRPPPEPGPPDPAGLLSQTAEVALDLVGDRTPTSEKMDEGQQSSGEDMEIS 642
Query: 480 GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAES----PPVEPGPGSLDAEAA 535
E +AP S PK + AAA P+ P PP+ P P +
Sbjct: 643 DDEMPSAPITSADCPKPMVVTPGAAAVAAPSVLAPTLPLPPPPGFPPLPPPPPPPPPQPG 702
Query: 536 APERPKAERAEAPPAGAERA 555
P P PP A A
Sbjct: 703 FPMPPPLPPPPPPPPPAHPA 722
Score = 37.0 bits (84), Expect = 0.089
Identities = 54/235 (22%), Positives = 81/235 (34%), Gaps = 31/235 (13%)
Query: 646 SPAGPRK-SPQEAAAAPGTREPCPA---AQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQ 701
+P PR +P ++ +R+P P+ +Q+PA V ++ K+ D ++
Sbjct: 273 TPLTPRLGTPFSQDSSYSSRQPTPSYLFSQDPA---------VTFKARRHESKFTDAYNR 323
Query: 702 --EVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGK-----ARPPE 754
E V A + + P G G+ P + + + A P
Sbjct: 324 RHEHHYVHNSPAVTAVAGATAAFRGSSDLPFGAVGGTGGSSGPPFKAQPQDSATFAHTPP 383
Query: 755 PLSSKPPLPRKPLLQSFTLP--HQPAPPD-----AGPGEREPRKEPRTAEKRPLRRGAEK 807
P + P K + P H P PP+ A G R+ + R PL
Sbjct: 384 PAQATPAPGFKSAFSPYQTPVAHFPPPPEEPTATAAFGARDSGEFRRAPAPPPL----PP 439
Query: 808 SLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAK 862
+ P A PG P PP R T P D PG TL+S P K
Sbjct: 440 AEPLAKEKPGTPPGPPPPDTNSMELGGRPTFGWSPEPCDSPGTPTLESSPAGPEK 494
>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
Length = 1233
Score = 96.7 bits (239), Expect = 9e-20
Identities = 188/783 (24%), Positives = 274/783 (34%), Gaps = 126/783 (16%)
Query: 86 LGSRALSHDSIFIPESGQDATRPVRVFSQENVCDRIKALQLKIQCNVKMGPPPPPGGLPA 145
+G+RA SHDSIFIP+ G ++ + V+ SQ+N+ ++K LQ ++ N+K G P +P
Sbjct: 1 MGTRAFSHDSIFIPDGGAESEQTVQAMSQDNILGKVKTLQQQLGKNIKFG-QRSPNAIPM 59
Query: 146 KRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARIS--DNSL 203
+ S E+D SP E+ D+ S +P +S + S + +
Sbjct: 60 NKANSGEASLEEDLFLTSPMEIVTQQDIVLSDAENKSSDTPSSLSPLNLPGAGSEMEEKV 119
Query: 204 APVADFSYPAESSSC-----------------LDNSAAKHKLQVKPRNQR-SSKMRRLSS 245
APV SS LDNSAAKHKL VKP+ QR S K RRL+
Sbjct: 120 APVKPSRPKRHFSSAGTIESVNLDAIPLAIARLDNSAAKHKLAVKPKKQRVSKKHRRLAQ 179
Query: 246 RAQSE--SLSDLTCTPEE-EENEEKPLL-EVSPEERPSSGQQDVAPDRGPEPGPPAPLPP 301
Q E L C + E+KP E P S ++ D E
Sbjct: 180 DPQHEQGGLESRPCLDQNGHPGEDKPTWHEEEPNPLDSEEERRRQEDYWRELEAKCKRQK 239
Query: 302 PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGP 361
A RR Q AL + E EL E E EPP E
Sbjct: 240 AEAAEKRRLEEQRLQALERRLWE----------ENRRQELLEEEGEGQ---EPPLEAERA 286
Query: 362 PNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDP--- 418
P +Q P A ++ E E+ + E D
Sbjct: 287 PRE----EQQRSLEAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLE 342
Query: 419 ---AATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTE 475
E + +R +EAE L +E GP PE ET R G E
Sbjct: 343 ERRRQEEEEGRCAEELKRQEEEEAEGWEE-LEQQEAEVQGP---PEALEETGEGR-RGAE 397
Query: 476 PERIGTEPSTAPAPSPP--APKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAE 533
E +G E A S L + E P E PG + +
Sbjct: 398 EEDLGEEEEEGQAHLEDWRGQLSELLNDFEERLEDQERLKPEGQREH---SEEPGICEEQ 454
Query: 534 AAAPERPKAERAEAPP-AGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLE 592
ER + ++ + GA+R PE K E G E PL
Sbjct: 455 NPEAERRREQQGRSGDFQGADRPGPEEKREEGDTE----------------------PLL 492
Query: 593 RASGRLPLARSGPVWRSEAA---------------LDDLQGLPEPQ--HAKPGPRKLAER 635
+ G + A+ PV R EAA +D+ Q +P P G +++
Sbjct: 493 KQEGPVEAAQP-PVERKEAAALEQGRKVEELRWQEVDERQTMPRPYTFQVSSGGKQILFP 551
Query: 636 GPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKY 695
S A G +PQE P A + +P + P + + T++ +
Sbjct: 552 KVNLSPVTPAKDTGLTAAPQE-----------PKAPKASPVQHALPSSLSVPHTAILV-- 598
Query: 696 RDGASQEVKGVKRYSAEVRLERSLTVLPKEEK----CPLGTAPALRGTRAPSD--QGKGK 749
++ G ++++ ++L EEK P G P R P D G GK
Sbjct: 599 ---TGAQLCGPAVNLSQIKDTACKSLLGLEEKKHAEAPAGENP----PRGPGDARAGSGK 651
Query: 750 ARP-PEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKS 808
A+P E SS L ++S L + + P + ++ + T R RG ++
Sbjct: 652 AKPRQESPSSASALAEWASIRSRILKNAESDPRSSERDQLRPGDESTPRGRCDSRGNQRK 711
Query: 809 LPP 811
PP
Sbjct: 712 TPP 714
Score = 84.7 bits (208), Expect = 4e-16
Identities = 196/943 (20%), Positives = 304/943 (32%), Gaps = 215/943 (22%)
Query: 223 AAKHKLQVKPRNQRSSKMRRLSSRAQSESL------SDLTCTPEEEENEEKPLLEVS-PE 275
A + + + + R + + RRL ++AQ+E + L +EE E + E+ E
Sbjct: 303 AERREREERERLEAEEERRRLQAQAQAEERRRLEEDARLEERRRQEEEEGRCAEELKRQE 362
Query: 276 ERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGED---- 331
E + G +++ GPP L G R R L EEG ED
Sbjct: 363 EEEAEGWEELEQQEAEVQGPPEALEETGEGR----RGAEEEDLGEEEEEGQAHLEDWRGQ 418
Query: 332 -------------------------PSSRPATPELAEPESAPTLRVEPPSPP-EGPPNPG 365
S P E PE+ + S +G PG
Sbjct: 419 LSELLNDFEERLEDQERLKPEGQREHSEEPGICEEQNPEAERRREQQGRSGDFQGADRPG 478
Query: 366 PDGGKQDGEAPPA----GPCAPATDKAEEVVCAP------------------EDVASPFP 403
P+ +++G+ P GP A E A + + P+
Sbjct: 479 PEEKREEGDTEPLLKQEGPVEAAQPPVERKEAAALEQGRKVEELRWQEVDERQTMPRPYT 538
Query: 404 TAIPEGDTT----PPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPP----- 454
+ G P ++ P+ +A P LP P
Sbjct: 539 FQVSSGGKQILFPKVNLSPVTPAKDTGLTAAPQEPKAPKASPVQHALPSSLSVPHTAILV 598
Query: 455 ------GPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEG 508
GPA + +T + G E ++ P+ P P + E
Sbjct: 599 TGAQLCGPAVNLSQIKDTACKSLLGLEEKKHAEAPAGENPPRGPGDARAGSGKAKPRQES 658
Query: 509 PAASPPLAAAES------PPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPE---- 558
P+++ LA S E P S + + P R G +R P
Sbjct: 659 PSSASALAEWASIRSRILKNAESDPRSSERDQLRPGDESTPRGRCDSRGNQRKTPPVNAK 718
Query: 559 -------RKAERGGAELRGAKKFSVSSCRARPRPGVSR---PLERASGRLPLARSGPVWR 608
+K GG E + S R RP G S P +G L + GP +
Sbjct: 719 FSIMPAWQKFSDGGTET-SKQSTEAESIRKRPMLGPSEETAPQPPPAGVRELGK-GPE-K 775
Query: 609 SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668
SE + + AK P L P A S E A G +P P
Sbjct: 776 SEMHREPADTTEGCKFAKDLPSFLVPSLPYPPQKVVAHTEFTTSSDSETAN--GIAKPDP 833
Query: 669 AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSA-------------EVRL 715
P E +PF +KLR T+ SL++ E K KR+S+ R
Sbjct: 834 VM--PGGEEKASPFGIKLRRTNYSLRFNCDQQAEQKKKKRHSSTGDSADAGPPAAGSARG 891
Query: 716 ERSLT--------VLPKEEK-----------------CPL---GTAPALRGTRAPSDQGK 747
E+ + LP+E K P+ G PA T AP
Sbjct: 892 EKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVAHPGPPPASSQTPAPEHDKA 951
Query: 748 GKARP--------PEPLSSKPPL-PRKPLLQSFTL-------------PHQPAPPDAGPG 785
P P+P S PP P L + + + P +P+ D
Sbjct: 952 ANKMPLAQKPALAPKPTSQTPPASPLSKLSRPYLVELLSRRAGRPDPEPSEPSKEDQESS 1011
Query: 786 EREPRKEPRTAEKRPLRRGAE-----------------------------KSLPPAATGP 816
+R P P E++ +R E K P +
Sbjct: 1012 DRRPPSPPGPEERKGQKRDEEEEATERKPASPPLPATQQEKPSQTPEAGRKEKPMLQSRH 1071
Query: 817 GADGQPA--------PPWITVTRQKRRGTLDQPPNQEDKPGARTLK-----SEPGKQAKV 863
DG P WIT+ QK++G +Q +E++ AR K S+ V
Sbjct: 1072 SLDGSKLTEKVETAQPLWITLALQKQKGFREQQATREERKQAREAKQAEKLSKENVSVSV 1131
Query: 864 PERGQEPVKQADFVRSKSFLITPVKP--AVDR-KQGAKLNFKEGLQRGISLSHQNLAQSA 920
+ G V +A + + L +P AV R ++ +L L +++ + A A
Sbjct: 1132 -QPGSSSVSRAGSLHKSTALPEEKRPETAVSRLERREQLKKANTLPTSVTVEISDSAPPA 1190
Query: 921 VMMEKELHQLKRASYASTD-QPSWMELARKKSQAWSDMPQIIK 962
++++ + A +P+W+ LA++K++AWSD PQIIK
Sbjct: 1191 PLVKEVTKRFSTPDAAPVSTEPAWLALAKRKAKAWSDCPQIIK 1233
Score = 34.7 bits (78), Expect = 0.44
Identities = 43/193 (22%), Positives = 70/193 (36%), Gaps = 21/193 (10%)
Query: 201 NSLAPVADFSYPAESSSC----LDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLT 256
+S AD PA S+ ++ A KH + +++ RR S+ S +
Sbjct: 873 SSTGDSADAGPPAAGSARGEKEMEGVALKHGPSLPQERKQAPSTRRDSAEPSSSRSVPVA 932
Query: 257 CTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSS 316
+ + P +PE ++ + +A P P + PP ++L
Sbjct: 933 HPGPPPASSQTP----APEHDKAANKMPLAQKPALAPKPTSQTPPASPL----SKLSRPY 984
Query: 317 ALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGP--DGGKQDGE 374
+ G P +PS P + ES+ PPSPP G D ++ E
Sbjct: 985 LVELLSRRAGRPDPEPSE----PSKEDQESSDR---RPPSPPGPEERKGQKRDEEEEATE 1037
Query: 375 APPAGPCAPATDK 387
PA P PAT +
Sbjct: 1038 RKPASPPLPATQQ 1050
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 96.3 bits (238), Expect = 1e-19
Identities = 177/664 (26%), Positives = 227/664 (34%), Gaps = 150/664 (22%)
Query: 314 HSSALTASVEE-----GGVPGEDPSSRPATPELAEPESAPTLRVEP----PSPPEGPP-- 362
H + +AS EE G G P+S P TP+ A E++ EP P PP PP
Sbjct: 358 HRDSQSASGEERPPEADGKKGNSPNSEPPTPKTAWAETSRPPETEPGPPAPKPPLPPPHR 417
Query: 363 ----NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP-------EGDT 411
N GP G D PP P AP D+ E + +S A+ E +
Sbjct: 418 GPAGNWGPPGDYPDRGGPPCKPPAPE-DEDEAWRQRRKQSSSEISLAVERARRRREEEER 476
Query: 412 TPPETDPAATSE----------APSARDGPERSVPKEAEPTP---PVLPDEEKGPPGPAP 458
E AA +E AP R E + P A TP P +P E PP P P
Sbjct: 477 RMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPP 536
Query: 459 EPEREAETEPERGAGTEPERIGTEPSTA-PAPSPPAPKSCLKHRPAAASEGPAASPPLAA 517
ETEPE EP+ A PA S P P G AA+P L +
Sbjct: 537 ASAPTPETEPE------------EPAQAPPAQSTPTP-------------GVAAAPTLVS 571
Query: 518 AESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVS 577
GS +A P+ P E E P E P E +G +
Sbjct: 572 GGGSTSSTSSGSFEASPVEPQLPSKEGPEPP----EEVPPPTTPPVPKVEPKGD---GIG 624
Query: 578 SCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAK-PGPRKLAERG 636
R P G+ P + S R + E L Q QH + P
Sbjct: 625 PTRQPPSQGLGYPKYQKSLPPRFQRQ----QQEQLLKQQQQHQWQQHQQGSAPPTPVPPS 680
Query: 637 PQDSGDRAASPAGPRKSPQEAAAAPGT--REP-------------CPAAQEPAPSEDRNP 681
P A PA P A PG R P P +P + R P
Sbjct: 681 PPQPVTLGAVPAPQAPPPPPKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPP 740
Query: 682 ---FPVKLRSTSLSLKYR-DGASQEVKGVKRYSAEVRLERS--------------LTVLP 723
+P + + L + R D + R++ + ER T P
Sbjct: 741 LDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDPKLAWVGDVFTATP 800
Query: 724 KEEKCPLGTAPALRGTRAPSDQGKGKARPPEP-----LSSKPPLPRK----PLLQSFTLP 774
E + PL T+P LR D+G PP P L+S P P P + F L
Sbjct: 801 AEPR-PL-TSP-LRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLE 857
Query: 775 HQ-PAPPDAGPGERE--------PRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPP 825
P P PG E P+KEP E L G E P A G G+ GQ PP
Sbjct: 858 EPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEETAQL-TGPEAGRKP-ARGVGSGGQGPPP 915
Query: 826 ----------WITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQ----AKVPERGQEPV 871
W RRG PP ++PGA ++ P K+ KV E +P+
Sbjct: 916 PRRESRTETRWGPRPGSSRRGI---PP---EEPGAPPRRAGPIKKPPPPTKVEELPPKPL 969
Query: 872 KQAD 875
+Q D
Sbjct: 970 EQGD 973
Score = 88.6 bits (218), Expect = 3e-17
Identities = 165/647 (25%), Positives = 214/647 (33%), Gaps = 91/647 (14%)
Query: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPA--PLPPPGGARARRARLQHSS 316
PE E P + P R +G D GPP P P R+ R Q SS
Sbjct: 399 PETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSS 458
Query: 317 ALTASVEEGGVPGEDPSSR----------PATPELAEPESAP--TLRVEPPSPPEGPPNP 364
++ +VE E+ R L E AP L+ EP +PP P P
Sbjct: 459 EISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTP 518
Query: 365 GPDGG-KQDGEAPPAGPCAPA---TDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAA 420
P ++ APPA P A A + EE AP ++P P ++
Sbjct: 519 APPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTPGVAAAPTLVSGGGSTSS 578
Query: 421 TSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPERE----AETEPERGAGTEP 476
TS E +P + P PP PP P EP+ + P +G G
Sbjct: 579 TSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPK 638
Query: 477 ERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAA 536
+ P K +H+ +G A PP SPP G++ A A
Sbjct: 639 YQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA--PPTPVPPSPPQPVTLGAVPAPQAP 696
Query: 537 PERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASG 596
P PKA P R P + + RP P SG
Sbjct: 697 PPPPKA----LYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSG 752
Query: 597 RLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERG--PQDS-----GD-RAASPA 648
+P RS S D +HA P L ERG P D GD A+PA
Sbjct: 753 LVPRERSDSGGSSSEPFD--------RHA---PAMLRERGTPPVDPKLAWVGDVFTATPA 801
Query: 649 GPR--KSPQEAAA---APGTREPCPAAQEP--------------APSEDRNPFPVKLRST 689
PR SP AA G R P P AP + FP++
Sbjct: 802 EPRPLTSPLRQAADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLE-EPG 860
Query: 690 SLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGK 749
L + G S EV A+++ PKEE L T P + G+
Sbjct: 861 PRPLPWPPG-SDEV-------AKIQTPPPKKEPPKEETAQL-TGP---------EAGRKP 902
Query: 750 ARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAE--KRPLRRGAEK 807
AR PP PR+ +P G EP PR A K+P +
Sbjct: 903 ARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVE 962
Query: 808 SLPPAATGPGADGQPAPPW---ITVTRQKRRGTLDQPPNQEDKPGAR 851
LPP G D P PP + +T+ K G + PPN P R
Sbjct: 963 ELPPKPLEQG-DETPKPPKPDPLKITKGKLGGPKETPPNGNLSPAPR 1008
Score = 74.3 bits (181), Expect = 5e-13
Identities = 177/790 (22%), Positives = 250/790 (31%), Gaps = 154/790 (19%)
Query: 136 PPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVS 195
P PPP P +E + ++PP S PG ++VS + ST S
Sbjct: 532 PAPPPASAPTPE-------TEPEEPAQAPPAQST---PTPGVAAAPTLVSGGGSTSSTSS 581
Query: 196 ARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDL 255
+ + P E + +V+P+ R+ S+
Sbjct: 582 GSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGDGIGPTRQPPSQGLGYPKYQK 641
Query: 256 TCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315
+ P + +++ LL+ + + QQ AP P PP P
Sbjct: 642 SLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQP----------------- 684
Query: 316 SALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEA 375
V G VP P + P P+ P + L PP PP
Sbjct: 685 ------VTLGAVPA--PQAPPPPPKALYPGA---LGRPPPMPPM-------------NFD 720
Query: 376 PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
P P D P D P P G +D +S P R P
Sbjct: 721 PRWMMIPPYVDPRLLQGRPPLDFYP--PGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLR 778
Query: 436 PKEAEPTPPVLP------DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489
+ P P L P P P R+A E ++G +E T P P
Sbjct: 779 ERGTPPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGMRSE---------TPPVP 829
Query: 490 SPPAPKSCLKHRPAAASEGPAASP-PLAAAESPPVEPGPGS-----LDAEAAAPERPKAE 543
PP + P + GP S PL P+ PGS + E PK E
Sbjct: 830 PPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPPKKEPPKEE 889
Query: 544 RAE--APPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSR---PLERASGRL 598
A+ P AG + P R GG ++ S + R PRPG SR P E
Sbjct: 890 TAQLTGPEAGRK---PARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEEPGA-- 944
Query: 599 PLARSGPVWR--SEAALDDL------QGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP 650
P R+GP+ + +++L QG P+ KP P K+ + GP
Sbjct: 945 PPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITK----------GKLGGP 994
Query: 651 RKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYS 710
+++P G P P + E P + R R + G +
Sbjct: 995 KETPPN-----GNLSPAPRLRRDYSYERVGPTSCRGRGRG-EYFARGRGFRGTYGGRGRG 1048
Query: 711 AEVRLERSLTVLPKEEKCPLGTA-----PALRGTRAPSDQGKG----------KARPPE- 754
A R RS ++ GT PA RG A + +G + R E
Sbjct: 1049 ARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSET 1108
Query: 755 ----------PLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPR-----TAEKR 799
P + P P++ L +P P PP A P R R T
Sbjct: 1109 GSETHESDLAPSDKEAPTPKEGTLTQ--VPLAPPPPGAPPSPAPARFTARGGRVFTPRGV 1166
Query: 800 PLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSE--P 857
P RRG PP PG +PP ++ +K PP P LK + P
Sbjct: 1167 PSRRGRGGGRPPPQVCPGW----SPPAKSLAPKK-------PPTGPLPPSKEPLKEKLIP 1215
Query: 858 GKQAKVPERG 867
G + V G
Sbjct: 1216 GPLSPVARGG 1225
Score = 50.8 bits (120), Expect = 6e-06
Identities = 164/816 (20%), Positives = 238/816 (29%), Gaps = 188/816 (23%)
Query: 19 GEDSTGKKKSKFKTFKKFFGKKKRKESPSSTGSSTWKQSQTRNEVIAIESGPVGYDSEDE 78
G G + +F+++++F G R + +T +E + S +E
Sbjct: 1043 GGRGRGARSREFRSYREFRGDDGRGGGTGGPNHPPAPRGRTASETRSEGS------EYEE 1096
Query: 79 LEESRGTLGSRALS--HDSIFIPESGQDATRPVRVFSQENVCDRIKALQLKIQCNVKMGP 136
+ + R GS S H+S P + T +Q V + P
Sbjct: 1097 IPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQ-----------------VPLAP 1139
Query: 137 PPP--------------------PGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPG 176
PPP P G+P++RG G SPP SL P
Sbjct: 1140 PPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKPP- 1198
Query: 177 TTIKVSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSA-------AKHKLQ 229
P S + ++ L+PVA S+ +++ + + Q
Sbjct: 1199 -------TGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQ 1251
Query: 230 VKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERP----------- 278
KP R K R ++ SE LT P E+ L V+ P
Sbjct: 1252 DKPPRFRRLKQERENAARGSEGKPSLTL-PASAPGPEEALTTVTVAPAPRRAAAKSPDLS 1310
Query: 279 -------------SSGQQDVAPDR--GPEPGPPAPLPP-----PGGARARRARLQHSSAL 318
+S D +R E PP L P PGG
Sbjct: 1311 NQNSDQANEEWETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGG----------- 1359
Query: 319 TASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPA 378
G VPG SR + A+ S + + P PGP GGK +
Sbjct: 1360 ------GAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGP-GGKAGSSGSSS 1412
Query: 379 GPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKE 438
G P G T P D + + PE P
Sbjct: 1413 GGGGGG----------------------PGGRTGPGRGDKRSWPSPKNRSRPPEERPPGL 1450
Query: 439 AEPTPP-----VLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAP----AP 489
P PP V ++ PA + A+ +G+ T P G P P AP
Sbjct: 1451 PLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAP---GGHPRHKPGLPQAP 1507
Query: 490 SPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPP 549
P+P+ ++ P + G ++ P E P+ G G ++A +R E PP
Sbjct: 1508 QGPSPRPPTRYEPQRVNSGLSSDPHF--EEPGPMVRGVGGTPRDSAGVSPFPPKRRERPP 1565
Query: 550 AGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRS 609
E E + G+K G RL A S +R
Sbjct: 1566 RKPELLQEESLPPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRP 1625
Query: 610 EAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAAS--PAGPRKSP----QEAAAAPGT 663
+ ++ L + ++ G SGD S P R SP + AA P
Sbjct: 1626 SSMEPWMEPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK 1685
Query: 664 R-------EPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLE 716
R P P R P P DG +E
Sbjct: 1686 RPGGSSPLNAVPCEGPPGSEPPRRPPPAP----------HDGDRKE-------------- 1721
Query: 717 RSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARP 752
LP+E+ P G R R G RP
Sbjct: 1722 -----LPREQPLPPGPIGTERSQRTDRGTEPGPIRP 1752
Score = 50.1 bits (118), Expect = 1e-05
Identities = 125/564 (22%), Positives = 180/564 (31%), Gaps = 100/564 (17%)
Query: 367 DGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPS 426
D G+ G P P AP A E + G T ET + APS
Sbjct: 1063 DDGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDL--APS 1120
Query: 427 ARDGPERSVPKEAEPTP-PVLPDEEKGPPGPAPE----------PEREAETEPERGAGTE 475
++ P PKE T P+ P PP PAP R + RG G
Sbjct: 1121 DKEAP---TPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRP 1177
Query: 476 PERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEP-----GPGSL 530
P P P SPPA KS +P P+ P P+ P G
Sbjct: 1178 P------PQVCPGWSPPA-KSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGS 1230
Query: 531 DAEAAAPERPK------AERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPR 584
+ ERP+ A++ + PP A RG + +
Sbjct: 1231 NVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARG----------------SEGK 1274
Query: 585 PGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQ------ 638
P ++ LP + GP E AL + P P+ A L+ +
Sbjct: 1275 PSLT---------LPASAPGP----EEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEW 1321
Query: 639 ----DSGDRAASPAGPRKSPQEAAAAP---GTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
+S D + G +++P P GT P S L +
Sbjct: 1322 ETASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMSRG---DLSQRAK 1378
Query: 692 SLKYRDGASQEVKGVKRYSAEV----RLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGK 747
L R +SQ G++R + + S + P G RG + K
Sbjct: 1379 DLSKRSFSSQR-PGMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPK 1437
Query: 748 GKARPPEPLSSKPPLPRKPLLQSF------TLPHQPAPPDAGPGEREPRKEPRTAEKRPL 801
++RPPE PLP P S + PA + R+ TA
Sbjct: 1438 NRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHP 1497
Query: 802 RRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQA 861
R + LP A GP P PP ++ G P +E P R + P A
Sbjct: 1498 RH--KPGLPQAPQGP----SPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSA 1551
Query: 862 KV----PERGQEPVKQADFVRSKS 881
V P+R + P ++ + ++ +S
Sbjct: 1552 GVSPFPPKRRERPPRKPELLQEES 1575
Score = 42.7 bits (99), Expect = 0.002
Identities = 63/270 (23%), Positives = 96/270 (35%), Gaps = 32/270 (11%)
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPSSG--QQDVAPDRGPEPGPPAPLPPPGGARA 307
E LS E ++ +++S + + SSG Q +PD G + P PGG
Sbjct: 1633 EPLSPFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGG--- 1689
Query: 308 RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPD 367
SS L A EG E P P P + + P + PP P + D
Sbjct: 1690 -------SSPLNAVPCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTD 1742
Query: 368 GGKQDGEAPPAGPCAP-----ATDKAEEV-------VCAPEDVASPFPTAIPEGDTTPPE 415
G + G P+ P +DK ++ + A +++ + AIP
Sbjct: 1743 RGTEPGPIRPSHRPGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELL 1802
Query: 416 TDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTE 475
AA++E S VP+ + + P+ G GP+ + + +
Sbjct: 1803 PSAAASAEPQSKNLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSG 1862
Query: 476 PERIGTEPSTAP-------APSPPAPKSCL 498
R GT PS P P PAP S L
Sbjct: 1863 GFRPGT-PSLHPYRSQPLYLPPGPAPPSAL 1891
Score = 38.9 bits (89), Expect = 0.023
Identities = 135/600 (22%), Positives = 201/600 (33%), Gaps = 110/600 (18%)
Query: 136 PPPPPGGLPAKRGEDAGMSSE--DDGLPRSPPEM-SLLHDVGPGTTIKVSVVSP------ 186
PPP G + E G +E D G P + + LH + + S + P
Sbjct: 1577 PPPHSSGFLGSKPEGPGPQAESRDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLS 1636
Query: 187 --DHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQR-SSKMRRL 243
+ V+ + +S S L+ + S S + K + P+ SS + +
Sbjct: 1637 PFEDVAGTEMSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPKRPGGSSPLNAV 1696
Query: 244 SSRAQSESLSDLTCTPEEEENEEKPLLEVSP-EERPSSGQQDVAPDRGPEPGPPAPLPPP 302
S P + + K L P P ++ DRG EPGP P P
Sbjct: 1697 PCEGPPGSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRP 1756
Query: 303 G-----GARARRA--------RLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES--- 346
G G + + L+ LTASV E D P+ AEP+S
Sbjct: 1757 GPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNL 1816
Query: 347 -APTLRVEPPSP-----PE------GPPNPGPDGGKQDGEAPP-AGPCAPATDKAE---- 389
+ EP S PE GP + GG D + P +G P T
Sbjct: 1817 DSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRS 1876
Query: 390 EVVCAPEDVASP---------------FPTA-------IPEGDTT-PPETDPAATSEAPS 426
+ + P A P F T +P G PP + + + PS
Sbjct: 1877 QPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYSPAFCPS 1936
Query: 427 ARDGPERSVPKEAEPTP------PVLPDEEKG-PPGPAPEPEREAETEPERGAGTEPERI 479
++ P+P P+ P + G P AP + P +
Sbjct: 1937 PLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLL---PMVDSQLPVVNF 1993
Query: 480 GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPER 539
G+ P AP P+PP P S L GPA PP A PP P L + A P
Sbjct: 1994 GSLPP-APPPAPP-PLSLLP-------VGPALQPPSLAVRPPPA-PATRVLPS-PARPFP 2042
Query: 540 PKAERAEAPPAGAERAAPERKAERGGAELRG---------AKKFSVSSCRARPRPGVSRP 590
RAE P P + ++ + L G + FS + R + P
Sbjct: 2043 ASLGRAELHPV---ELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSG 2099
Query: 591 LERASGRLPLARSGPVWRSEAALDDLQGLPEP-QHAKPGPRKLAERGPQDSGDRAASPAG 649
+ R R+ L ++ + D L+ +P+P + P PR+ R ++ G R G
Sbjct: 2100 VFRTQ-RVDL------YQQASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPG 2152
Score = 37.7 bits (86), Expect = 0.052
Identities = 53/225 (23%), Positives = 74/225 (32%), Gaps = 31/225 (13%)
Query: 296 PAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPP 355
P+PLP + R+ S + ++ GG G PS PA L + V
Sbjct: 1935 PSPLPDTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQMLLPMVDSQLPVVNFG 1994
Query: 356 SPPEGP-PNPGPDGGKQDGEA--PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTT 412
S P P P P P G A PP+ P A V+ +P A PFP ++ +
Sbjct: 1995 SLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSP---ARPFPASLGRAELH 2051
Query: 413 PPETDPAATSEAPSAR---DGPERSVP---------KEAEPTPPVLPD----------EE 450
P E P + S+ G R+ P + TP ++
Sbjct: 2052 PVELKPFQDYQKLSSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQ 2111
Query: 451 KGPPGP---APEPEREAETEPERGAGTEPERIGTEPSTAPAPSPP 492
PP P+P P G E G+ P PP
Sbjct: 2112 ASPPDALRWIPKPWERTGPPPREGPSRRAEEPGSRGDKEPGLPPP 2156
Score = 33.5 bits (75), Expect = 0.98
Identities = 97/420 (23%), Positives = 131/420 (31%), Gaps = 85/420 (20%)
Query: 454 PGPAPEPEREAETE---------PERGAGTEPERIGTEPSTA-----------PAPSPPA 493
P PA P +AE + P+ G G ++ ++P ++ P P+
Sbjct: 57 PPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDASTAQPPESQPLPASQT 116
Query: 494 PKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAE 553
P S RP AA E P + + D A+ + R E P A
Sbjct: 117 PASNQPKRPPAAPENTPLVPSGVKSWAQASVTHGAHGDGGRASSLLSRFSREEFPTLQAA 176
Query: 554 RAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAAL 613
+ ER AE S+ RP S GR P GP +
Sbjct: 177 GDQDKAAKERESAEQSSGPGPSL-------RPQNSTTWRDGGGRGPDELEGPDSKLHHGH 229
Query: 614 DDLQGLP---EPQHAK--------------PGPRKLAERGPQDSGDRAASPAGPRKSPQE 656
D GL PQ P P +GP R +P GP + P+
Sbjct: 230 DPRGGLQPSGPPQFPPYRGMMPPFMYPPYLPFPPPYGPQGPY----RYPTPDGPSRFPRV 285
Query: 657 A---AAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQE-VKGVKRYSAE 712
A + P R P + ED +LK D QE G E
Sbjct: 286 AGPRGSGPPMRLVEPVGRPSILKED-------------NLKEFDQLDQENDDGWAGAHEE 332
Query: 713 VRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPE-------PLSSKPPLPRK 765
V L +E+ A G R S G+ RPPE +S+PP P+
Sbjct: 333 VDYTEKLKFSDEEDGRDSDEEGA-EGHR-DSQSASGEERPPEADGKKGNSPNSEPPTPKT 390
Query: 766 PLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPP 825
++ PP+ PG P K P P RG + P P G P P
Sbjct: 391 AWAET------SRPPETEPGPPAP-KPPLP----PPHRGPAGNWGPPGDYPDRGGPPCKP 439
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 95.5 bits (236), Expect = 2e-19
Identities = 138/551 (25%), Positives = 186/551 (33%), Gaps = 77/551 (13%)
Query: 144 PAKRGEDAGMSSEDDGLPRSPP-EMSLLHDVGPGTTIKVSVVSPDHVSD-STVSARISDN 201
PA D+ LP SPP + SL V P + SP + +S+ S +
Sbjct: 447 PASTPPDSPPLQAPLSLPASPPLQTSLSPAVSP-------LSSPLTIHPLQALSSLASHS 499
Query: 202 SLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEE 261
AP++ P + +S A LQ P + + + L S A P
Sbjct: 500 PQAPLSSLIMPPLETQ---SSLAPPSLQTPPASLTTPPLENLPSLA-----------PPP 545
Query: 262 EENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPL--PPPGGARARRARLQHSSALT 319
+ PL E P P P PP+PL PPP + +
Sbjct: 546 LQTASAPLTTPHLETPP-------CPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598
Query: 320 ASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAG 379
AS G+P P S ATP P++ P L + P P PP +PP
Sbjct: 599 ASPPLQGLPSP-PLSPLATPP---PQAPPXLALPPLQAPPSPP-----------ASPPLS 643
Query: 380 PCAPATDKAEEVVC-----APEDVASPFPTAIPEGDTTPPETDPAAT--SEAPSARDGPE 432
P A + +A + AP P P P P+AT S+AP + P
Sbjct: 644 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 703
Query: 433 RSVPKEAEPTPPVLPDEEKGPPGPAP-------EPEREAETEPERGAGTEPERIGTEPST 485
VP +PP+ P P P P P + P + T P R+ +
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763
Query: 486 APAPSPPAPKSCLKHRPAAASEGPA----ASPPLAAAESPPVE-PGPGSLDAEAAAPERP 540
P PP+P + L P A A A+PPL A SPP PG A+ P P
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823
Query: 541 KA-ERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLP 599
A +APP A + L+ R P PG + L
Sbjct: 824 LATPPPQAPPVLAAPLLQVPPSPPASPTLQAP--------RRPPTPGPDTSVSGPRLTLA 875
Query: 600 LARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAA 659
LA P S + L G H+ E DSG + A P + AA
Sbjct: 876 LAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC 935
Query: 660 APG--TREPCP 668
P +R P P
Sbjct: 936 HPAAWSRGPAP 946
Score = 92.4 bits (228), Expect = 2e-18
Identities = 189/778 (24%), Positives = 265/778 (34%), Gaps = 112/778 (14%)
Query: 144 PAKRGEDAGMSSEDDG-LPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNS 202
P + AG + G P +P GT + + +P SAR +
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP--------SARPRPPT 202
Query: 203 LAPVADFSYPAESSSCLDNSAAKHK------LQVKPRNQRSSKMRRLSSRAQSESLSDLT 256
P S +E S+ + AA+ + LQ SS LSS A+S + T
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 257 CTPEEEENEEKPL-LEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315
++ KP L+ + + ++D AP GP P P P G +AR +
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDN 322
Query: 316 SALTASVEEGGVPGEDPSSRP-ATP-ELAEPE-SAPTLRVEPPSPPEGPPNPGPDGGKQD 372
+A +P P S P ATP LA P SAP PSPP PP+ P
Sbjct: 323 AATP-------LPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTP 375
Query: 373 G-EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGP 431
+APP+ P + +P A P P A+ T P + P
Sbjct: 376 PMQAPPSLQTIPPIQVPHSLT-SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434
Query: 432 ERSVPKEAEPTPPVLPDEEKGPPGPAP-----EPEREAETEPERGAGTEPERIGTEP--S 484
++ P+ P + PP AP P + P + P I S
Sbjct: 435 RQTQASLTSPSRPASTPPDS-PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS 493
Query: 485 TAPAPSPPAPKSCL----------------KHRPAAASEGPA------ASPPLAAAESP- 521
+ + SP AP S L + PA+ + P A PPL A +P
Sbjct: 494 SLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 522 -------PVEPGPGSLDAEAAA-----PERPKAERAEAPPAGAERAAPERK-------AE 562
P P P L A + PE P + P A A+P + +
Sbjct: 554 TTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSP 613
Query: 563 RGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEP 622
+ ++ +A P P S PL PLA P + A+ LQ P
Sbjct: 614 LATPPPQAPPXLALPPLQAPPSPPASPPLS------PLATPSPQAPNALAVHLLQA---P 664
Query: 623 QHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEP-APSEDRNP 681
P P A P S + S P ++P AA P P P A P +PS P
Sbjct: 665 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 724
Query: 682 -FPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTR 740
P L + L + AS + S + P PL AP L+
Sbjct: 725 QAPPPLAAPPLQVPPSPPASPPM--------------SPSATPPPRVPPLLAAPPLQVPP 770
Query: 741 APSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRP 800
+P + P PL+ KPP P L + L P+PP + PG+ P + P
Sbjct: 771 SPP-----ASLPMSPLA-KPPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASLPMSP 823
Query: 801 LRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPG 858
L ++ PP P P+PP + RR P P TL PG
Sbjct: 824 LATPPPQA-PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPG 879
Score = 79.0 bits (193), Expect = 2e-14
Identities = 123/471 (26%), Positives = 160/471 (33%), Gaps = 77/471 (16%)
Query: 136 PPPPPGGL--PAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDST 193
PP P + P + A S GLP SPP +S L P +P ++
Sbjct: 580 PPETPSSIATPPPQAPPALASPPLQGLP-SPP-LSPLATPPPQ--------APPXLALPP 629
Query: 194 VSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLS 253
+ A S + P++ + P+ + N+ A H LQ S ++ S S +S
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAP---NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 254 DLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQ 313
P ++ P L P + P S +P P PP PPP A +
Sbjct: 687 PSATPP----SQAPPSLAAPPLQVPPS--PPASPPMSPSATPPPQAPPPLAAPPLQ---- 736
Query: 314 HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPP-SPPEGPPNPGPDGGKQD 372
VP P+S P +P P P L PP P PP P
Sbjct: 737 -------------VPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPL-- 781
Query: 373 GEAPPAGPCAPATDKAEEVVCAPEDVASPFP----TAIPEGD--TTPPETDPAATSEAPS 426
+ PP P A AT + + P P ++P T PP+ P +
Sbjct: 782 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 841
Query: 427 ARDGPERSVPKEAEPTPPVL-PDEE-KGP-------PGPAPEPEREAETE--------PE 469
P S +A PP PD GP PGP P P R +
Sbjct: 842 VPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHS 901
Query: 470 RGAGTEPERI---GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESP----- 521
A + PE + + P A SPP PAA S GPA PPLA +P
Sbjct: 902 SSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGAPGAPLP 959
Query: 522 -PVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGA 571
P GPGS D E E A P GA P GG GA
Sbjct: 960 WPPATGPGSADGLCTIYETEGPESA-TPAPGALDPGPS-PGTSGGKAAAGA 1008
Score = 70.1 bits (170), Expect = 9e-12
Identities = 93/348 (26%), Positives = 121/348 (34%), Gaps = 40/348 (11%)
Query: 350 LRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEG 409
L PP P PP P + G A G P ++A + A + P A P
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGR-KPLAERAGGIGGAT--IPESAPRAGPTR 81
Query: 410 DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER----EAE 465
+PA S P++ G K P P P G P P ++ AE
Sbjct: 82 SAGTSSRNPA--SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 466 TEPERGAGTE-PERIGTEP-----STAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAE 519
RG TE P+R ++ P P P+P + R AA +E P +A
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR-AAGTEVGLPRPAPSARP 198
Query: 520 SPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSC 579
PP E GP + A +E + P+ A R R+ GG R A + SS
Sbjct: 199 RPPTE-GPRKSVSSA-------SEHSTTEPSPAAR----RRPSAGGGLQRPASRSLSSSA 246
Query: 580 RARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQD 639
P S P R + R P S P + LQ L PQ P GP
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKG------LQALRPPQVTPPRKDAAPALGPLS 300
Query: 640 SGDRAA-SPAGPRKSP-----QEAAAAPGTREPCPAAQEPAPSEDRNP 681
S A SP+G + P A P T P P P P +P
Sbjct: 301 SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSP 348
Score = 60.8 bits (146), Expect = 6e-09
Identities = 103/402 (25%), Positives = 137/402 (34%), Gaps = 55/402 (13%)
Query: 499 KHRPAAASEGPAASPPLAAAESPPVEPGPGS---------LDAEAAAPERPKAERA---- 545
K + AA+ PAA P PP P P L A A +P AERA
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 546 -EAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP----RPGVSRPLERASGRLPL 600
P A RA P R A S RA P PG RASG
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG---T 123
Query: 601 ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
R GP+ + + + + + A P++ A +P P + + A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGK-ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 661 PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLE---- 716
GT P PAPS P R + S +R SA L+
Sbjct: 183 AGTEVGLP---RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 717 RSLTVLPKEEKCPLGTAPALRGT-RAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPH 775
RSL+ P + P+ RGT RAP+ + K + + L +PP T P
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL--RPP--------QVTPPR 289
Query: 776 QPAPPDAGPGEREP--RKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQK 833
+ A P GP P P + RP+ + P AT P P+PP T
Sbjct: 290 KDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLP-----PSPPLATPLPL- 343
Query: 834 RRGTLDQPPNQEDKPGARTLKSEPG-KQAKVPERGQEPVKQA 874
PP+ P +TL S P ++ P P QA
Sbjct: 344 ------APPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQA 379
Score = 53.9 bits (128), Expect = 7e-07
Identities = 103/414 (24%), Positives = 135/414 (32%), Gaps = 68/414 (16%)
Query: 472 AGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE------------GPAASPPLAAAE 519
A P + P +P P PP + L+ AA + G A P A
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA 77
Query: 520 SPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELR----GAKKFS 575
P G S + + P + ER APPA P R R G K
Sbjct: 78 GPTRSAGTSSRNPASRPPASGRGER--APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLR 135
Query: 576 VS---------SCRARPRPGVSRPLER-ASGRLPLARSGPVWRSEAALDDLQGLPEP-QH 624
+S + A R +S R SG P S + R A GLP P
Sbjct: 136 ISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195
Query: 625 AKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQE--PAPSEDRNPF 682
A+P P GPRKS +A+ T EP PAA+ A + P
Sbjct: 196 ARPRP----------------PTEGPRKS-VSSASEHSTTEPSPAARRRPSAGGGLQRPA 238
Query: 683 PVKLRSTSLSLKYRDGASQEVKGVKRYSAE--------VRLERSLTVLPKEEKCPLGTAP 734
L S++ L + +G R A ++ R V P + P
Sbjct: 239 SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP 298
Query: 735 ALRGTRAPSDQGKGKARP-PEPLSSKPPLPR----KPLLQSFTLPHQPAPPDAGPGEREP 789
A KARP P P ++ PLP P L + LP P P A P +
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLAT-PLPLAPPSPSAPPSLQTL 357
Query: 790 RKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPN 843
P T P + + PP P Q PP I V +L PP+
Sbjct: 358 PSPPATP---PSQAPPSMTTPPMQAPPSL--QTIPP-IQVPHSLTSPSLQAPPS 405
Score = 32.0 bits (71), Expect = 2.9
Identities = 36/122 (29%), Positives = 42/122 (34%), Gaps = 31/122 (25%)
Query: 724 KEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLP----------------RKPL 767
K +K G A RAP G P P S +PP P RKPL
Sbjct: 4 KRDKAKAGAAARTPAARAP-----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL 58
Query: 768 LQ------SFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAA-TGPGADG 820
+ T+P + P AGP R R RP G + PPA T PG
Sbjct: 59 AERAGGIGGATIPE--SAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
Query: 821 QP 822
P
Sbjct: 116 SP 117
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 94.0 bits (232), Expect = 6e-19
Identities = 159/673 (23%), Positives = 234/673 (34%), Gaps = 118/673 (17%)
Query: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
P++ EEK + P P+ +V P + P P+PP A ++ +
Sbjct: 10473 PKKIVVEEKVRVPEEPRVPPTK-VPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKE 10531
Query: 319 TASVEEGGVPGEDPSSRPATPELAEPE----SAPTLRVEP--PSPPEGPPNPGPDGGKQ- 371
++ VP P +P P PE + P +V P PE PP P+ K+
Sbjct: 10532 VVPEKKVPVP---PPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEV 10588
Query: 372 --DGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARD 429
+ + P A P P +V AP++V +P PE P E P
Sbjct: 10589 VPEKKVPAAPPKKPEVTPV-KVPEAPKEVVPEKKVPVP--PPKKPEVPPTKVPEVPKVA- 10644
Query: 430 GPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489
PE+ VP+ P P E PP EPE A EP EPE T P P
Sbjct: 10645 VPEKKVPEAIPPKP------ESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVP-P 10697
Query: 490 SPPAPKSCLKHRPAAASEGPAASPPLAAAESP-PVEPGPGSLDAEAAAPERPKAERAEAP 548
P P+ K PA ++ P PP+ E P V P P++P+A A+ P
Sbjct: 10698 KKPVPE---KKAPAVVAKKPEL-PPVKVPEVPKEVVP---EKKVPLVVPKKPEAPPAKVP 10750
Query: 549 PAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWR 608
E PE+K V + E ++P PV
Sbjct: 10751 EVPKE-VVPEKKV------------------------AVPKKPEVPPAKVPEVPKKPV-- 10783
Query: 609 SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668
L++ +P P+ A+ P ++ E P + E AP +P P
Sbjct: 10784 ----LEEKPAVPVPERAESPPPEVYEE--------------PEEIAPEEEIAPEEEKPVP 10825
Query: 669 AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKC 728
A+E P P + + K E K E +E+ PK +
Sbjct: 10826 VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEK-----PKLKPR 10880
Query: 729 PLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLP------------HQ 776
P PA + KA P + + KP +P K L +P +
Sbjct: 10881 PPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERK 10940
Query: 777 PAPPD---------AGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWI 827
P P + P E EP+ EP+ EK +K P P + P
Sbjct: 10941 PEPKEEVVLKSVLRKRPEEEEPKVEPKKLEK------VKKPAVPEPPPPKPVEEVEVP-- 10992
Query: 828 TVTRQKRRGTLDQPPN-QEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITP 886
TVT+++R+ + +P E KP EP + PE + +K + + P
Sbjct: 10993 TVTKRERK--IPEPTKVPEIKPAIPLPAPEPKPK---PEAEVKTIKPPPVEPEPTPIAAP 11047
Query: 887 VK-PAVDRKQGAK 898
V P V +K AK
Sbjct: 11048 VTVPVVGKKAEAK 11060
Score = 76.3 bits (186), Expect = 1e-13
Identities = 139/596 (23%), Positives = 198/596 (33%), Gaps = 144/596 (24%)
Query: 353 EPPSPPEGP--------PNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPT 404
+P +PP+GP P P E P P P EE V PE+ P PT
Sbjct: 10435 KPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP-PT 10493
Query: 405 AIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREA 464
+PE PP KE P E+K P PA +PE
Sbjct: 10494 KVPE--VLPP----------------------KEVVP-------EKKVPVPPAKKPEAPP 10522
Query: 465 ETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAA---SEGPAASPPLAAAESP 521
PE PE+ P P P P + + P AA + P A PP + P
Sbjct: 10523 PKVPEAPKEVVPEKKVPVP---PPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPP 10579
Query: 522 PVEPGPGSLDAE----AAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVS 577
V P + E AA P++P+ + P A E PE+K + KK V
Sbjct: 10580 EVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKE-VVPEKK-----VPVPPPKKPEVP 10633
Query: 578 SCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGP 637
+ P V+ P ++ +P P+P+ P P E
Sbjct: 10634 PTKVPEVPKVAVPEKKVPEAIP--------------------PKPE--SPPPEVFEE--- 10668
Query: 638 QDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRD 697
P + E A EP PAA + P P K ++ K
Sbjct: 10669 ------------PEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKK--- 10713
Query: 698 GASQEVKGVK--RYSAEVRLERSL-TVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPE 754
E+ VK EV E+ + V+PK+ + P P + P + +P
Sbjct: 10714 ---PELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEV 10770
Query: 755 PLSSKPPLPRKPLLQS-----------------FTLPHQPAP----------PDAGPGER 787
P + P +P+KP+L+ + P + AP P E
Sbjct: 10771 PPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEE 10830
Query: 788 EPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDK 847
EP P + P + EK +P + P + + K + PP K
Sbjct: 10831 EPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPK 10890
Query: 848 PGAR----TLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITPVKPAVDRKQGAKL 899
+ LK+ P K KVPE+ Q P K +TP+K K+ KL
Sbjct: 10891 EDVKEKIFQLKAIPKK--KVPEKPQVPEKVE---------LTPLKVPGGEKKVRKL 10935
Score = 72.4 bits (176), Expect = 2e-12
Identities = 90/365 (24%), Positives = 129/365 (35%), Gaps = 68/365 (18%)
Query: 259 PEEEENEEKPLLEV-----SPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQ 313
P++ EEKP + V SP +++AP+ P P+P
Sbjct: 10779 PKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVP------------- 10825
Query: 314 HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGP--DGGKQ 371
A EE VP P + P P+ PE + +P +PP P P + K
Sbjct: 10826 -----VAEEEEPEVP---PPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKL 10877
Query: 372 DGEAPPAGPCAPATDKAEEVV---CAPEDVASPFPTAIPEGDTTP---PETDPAATSEAP 425
PP P P D E++ P+ P + + TP P + P
Sbjct: 10878 KPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLP 10937
Query: 426 SARDGPERSV---------PKEAEP-TPPVLPDEEKGPPGPAPEPEREAETEPERGAGTE 475
+ P+ V P+E EP P ++ K P P P P + E E E T+
Sbjct: 10938 ERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVE-EVEVPTVTK 10996
Query: 476 PERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAA 535
ER EP+ P P P + +P +E P PPVEP P + A
Sbjct: 10997 RERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKP-------PPVEPEPTPIAAPVT 11049
Query: 536 APERPKAERAEAP------PAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSR 589
P K A+AP P G + P++ AE R + RP G +
Sbjct: 11050 VPVVGKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERR----------KLRPGSGGEK 11099
Query: 590 PLERA 594
P + A
Sbjct: 11100 PPDEA 11104
Score = 63.5 bits (153), Expect = 9e-10
Identities = 135/670 (20%), Positives = 230/670 (34%), Gaps = 97/670 (14%)
Query: 225 KHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQD 284
+ K+ K +++ ++ + E + + EEE+ + + EVS + P +
Sbjct: 9162 ERKVPAKVPEKKAPPPPKVIKKPVIEKIEKTSRRMEEEKVQVTKVPEVSKKIVPQKPSRT 9221
Query: 285 VAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP 344
+ E PA ++ + AS E V P + +
Sbjct: 9222 PVQEEVIEVKVPA-------VHTKKMVISEEKMFFASHTEEEVSVTVPEVQKEIVTEEKI 9274
Query: 345 ESAPTLRVEPPSP-PEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAP-EDVASPF 402
A + RVEPP PE P P P+ + P P K EV P + P
Sbjct: 9275 HVAISKRVEPPPKVPELPEKPAPE---EVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPV 9331
Query: 403 PTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER 462
P P+ +PAA + P P++ VP+E P P + +++ PP PE ++
Sbjct: 9332 PV---------PKKEPAAPPKVPEV---PKKPVPEEKIPVP--VAKKKEAPPAKVPEVQK 9377
Query: 463 EAETEPERGAGTEPERIGTEPSTAPAPS-PPAPKSCLKHRPAAASEGPAASPPLAAAESP 521
TE E I T+ +P P+ P PK + PP P
Sbjct: 9378 GVVTE-------EKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPP------P 9424
Query: 522 PVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRA 581
P P A P++P E A P + AP +AE + K+F
Sbjct: 9425 PKVP---------ALPKKPVPEEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAE---- 9471
Query: 582 RPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSG 641
E+ S +P + V R E + ++ E +
Sbjct: 9472 ----------EKLSFAVP--QRVEVTRHEVSAEEEWSYSEEEEGV--------------- 9504
Query: 642 DRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQ 701
+ S + +E A E +E E + ++ + + R Q
Sbjct: 9505 --SISVYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTER----Q 9558
Query: 702 EVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPP 761
E K V + ++E P K P + + P+ K + PP + P
Sbjct: 9559 EKKIVLKPKIPAKIEE-----PPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKV---PE 9610
Query: 762 LPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQ 821
P+KP+ + P + P + R T E++ L +K PP A P +
Sbjct: 9611 EPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEEKVLVAVTKKEAPPKARVPEEPKR 9670
Query: 822 PAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKS 881
P + + +R ++PP + + R +K E + P+R +P+K+ + K
Sbjct: 9671 AVPEEKVLKLKPKRE--EEPPAKVTEFRKRVVKEEK-VSIEAPKREPQPIKEVTIMEEKE 9727
Query: 882 FLITPVKPAV 891
T + AV
Sbjct: 9728 RAYTLEEEAV 9737
Score = 62.4 bits (150), Expect = 2e-09
Identities = 84/334 (25%), Positives = 125/334 (37%), Gaps = 54/334 (16%)
Query: 265 EEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEE 324
EEK + + +E+P + P + P P P+P P A A++ ++
Sbjct: 9986 EEKVPVLIPKKEKPPPAKVPEVPKK-PVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKK 10044
Query: 325 GGVPGED-----PSSRPATPELAEPESA-PT---LRVEPPSPPEGP----PNPGPDGGKQ 371
VP P+ P P+ PE PT +VE P PP+ P P P P Q
Sbjct: 10045 VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAP-PPKVPKKREPVPVPVALPQ 10103
Query: 372 DGEAPPAGPCAPATD---KAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSE--APS 426
+ E P + + EEV+ E+V +PE + PPE + E P
Sbjct: 10104 EEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEEYVPE 10163
Query: 427 ARDG-PERSVPKEAEPTPPV-----------------LPDEEKGPPGPAPEPEREAETEP 468
+ PE V E +P PV +P +E+ PP PE ++ E E
Sbjct: 10164 EEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVE-EK 10222
Query: 469 ERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPG 528
E E + E + P P + + + P + E +PP P V
Sbjct: 10223 RIILPKEEEVLPVEVTEEPEEEPISEEE-IPEEPPSIEEVEEVAPP----RVPEV----- 10272
Query: 529 SLDAEAAAPERPK--AERAEAPPAGAERAAPERK 560
+ A PE P ++ EAPPA + PE K
Sbjct: 10273 ---IKKAVPEAPTPVPKKVEAPPAKVSKKIPEEK 10303
Score = 58.9 bits (141), Expect = 2e-08
Identities = 143/669 (21%), Positives = 226/669 (33%), Gaps = 129/669 (19%)
Query: 259 PEEEE-----NEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQ 313
PEEEE E P E PEE +++V P+ P+ PAP+P + ++
Sbjct: 10142 PEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP------EIKKKVT 10195
Query: 314 HSSALTASVEEGGVPGEDPSSRPATPELAE------PESAPTLRVEPPSPPEGPPNPGPD 367
+ EE P+ P P+ E P+ L VE PE P
Sbjct: 10196 EKKVVIPKKEEA-----PPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEP----- 10245
Query: 368 GGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSA 427
E P P P+ ++ EEV AP V A+PE T P+ EAP A
Sbjct: 10246 ---ISEEEIPEEP--PSIEEVEEV--APPRVPEVIKKAVPEAPTPVPK-----KVEAPPA 10293
Query: 428 RDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAP 487
+ + +P+E P P +++ PP PE ++ PE+ P
Sbjct: 10294 K--VSKKIPEEKVPVP---VQKKEAPPAKVPEVPKKV-----------PEKKVLVPKKEA 10337
Query: 488 APSPPAPKSCLKHRPAAASEGPAA-----SPPLAAAESPPVEPGPGSLDAEAAAPERPKA 542
P P ++ L+ + + A + AE + + E E
Sbjct: 10338 VP-PAKGRTVLEEKVSVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFH 10396
Query: 543 ERAEAPPAGAERAAPERKAER--GGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPL 600
E E R E + E+ E+ A++ V P G + + P
Sbjct: 10397 EVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPP 10456
Query: 601 ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
+ P R E P P+K+ ++ P PR P +
Sbjct: 10457 TKVVP--RKE----------PPAKVPEVPKKIVVE------EKVRVPEEPRVPPTKVPEV 10498
Query: 661 PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLT 720
+E P + P P + P V EV E+ +
Sbjct: 10499 LPPKEVVPEKKVPVPPAKKPEAP-------------------PPKVPEAPKEVVPEKKVP 10539
Query: 721 VLP-KEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKP--LLQSFTLPHQP 777
V P K+ + P P + P ++ +A PP+P S P +P P ++ +P P
Sbjct: 10540 VPPPKKPEVPPTKVPEVPKAAVP-EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAP 10598
Query: 778 -------------APPDAGPGEREPRKEPRTAEKRPLR--RGAEKSLPPAATGPGADGQP 822
AP + P ++ P P+ E P + + ++P +P
Sbjct: 10599 PKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKP 10658
Query: 823 APPWITVTRQKRRGTLDQPPN---QEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRS 879
P V + L++PP +E +P A Q VP + P K+A V +
Sbjct: 10659 ESPPPEVFEEPEEVALEEPPAEVVEEPEPAA-------PPQVTVPPKKPVPEKKAPAVVA 10711
Query: 880 KSFLITPVK 888
K + PVK
Sbjct: 10712 KKPELPPVK 10720
Score = 48.9 bits (115), Expect = 2e-05
Identities = 118/579 (20%), Positives = 193/579 (33%), Gaps = 83/579 (14%)
Query: 386 DKAEEVVCAPEDVASPFPTA-IPEGDT-TPPETDPAATSEAPSARDGPERSVPKEAEPTP 443
++ EE + PE P P +PE T P+ PA + + +PK+ +P P
Sbjct: 9780 EEHEEYITEPE---KPIPVKPVPEEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPP 9836
Query: 444 PVLPDE-----EKGPPGPAPEPEREAETEPERGAGTEPERIGTEPS--------TAPAPS 490
P +P+E E+ + E+E TEP +P+R+ E P
Sbjct: 9837 PKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRV 9896
Query: 491 PPAPKSCLKHRPAAASEGPA----------------ASPPLAAAESPPVEPGPGSLDAEA 534
P PK A E + E PV P
Sbjct: 9897 PEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRK 9956
Query: 535 AAPER----PKAERAEAPPAGAERA--APERKAERGGAELRGAKKFSVSSCRARPRP--- 585
PE P ++ EAPPA PE K + V +P P
Sbjct: 9957 PVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEK 10016
Query: 586 ---GVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGD 642
V + +E ++P PV + +P P+ + P K+ E + +
Sbjct: 10017 VPVPVPKKVEAPPAKVPEVPKKPVPEKKVP------VPAPKKVEAPPAKVPEVPKKLIPE 10070
Query: 643 RAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQE 702
P+K P REP P P E+ F ++ L + E
Sbjct: 10071 EKKPTPVPKKVEAPPPKVPKKREPVP-VPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPE 10129
Query: 703 VKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTR-APSDQGKGKARPPEPLSSK-P 760
+ V EV L + P+EE+ P P ++ + +P P+ + P
Sbjct: 10130 EEEVLPEEEEV-LPEEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 761 PLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGAD- 819
+ +K + +P + P A + P + EKR + E+ LP T +
Sbjct: 10189 EIKKKVTEKKVVIPKKEEAPPA----KVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEE 10244
Query: 820 -----------------GQPAPPWITVTRQKRRGTLDQP-PNQEDKPGARTLKSEPGKQA 861
+ APP + +K P P + + P A+ K P ++
Sbjct: 10245 PISEEEIPEEPPSIEEVEEVAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPEEKV 10304
Query: 862 KVPERGQE--PVKQADFVRS--KSFLITPVKPAVDRKQG 896
VP + +E P K + + + ++ P K AV +G
Sbjct: 10305 PVPVQKKEAPPAKVPEVPKKVPEKKVLVPKKEAVPPAKG 10343
Score = 46.6 bits (109), Expect = 1e-04
Identities = 161/760 (21%), Positives = 266/760 (35%), Gaps = 95/760 (12%)
Query: 136 PPPPPGGLPAKR--GEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDST 193
PPP +P K+ E + +++ +P PP++ L P KV+V P
Sbjct: 9395 PPPAVPEIPKKKVPEERKPVPRKEEEVP-PPPKVPALPKK-PVPEEKVAVPVPVAKKAPP 9452
Query: 194 VSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLS 253
A +S ++ V + + AE A +++V + + S + S+S
Sbjct: 9453 PRAEVSKKTV--VEEKRFVAEEKLSF---AVPQRVEVTRHEVSAEEEWSYSEEEEGVSIS 9507
Query: 254 DLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQ 313
EEE EE+ EV+ E ++ V ++ P + ++
Sbjct: 9508 ----VYREEEREEEEEAEVTEYEVMEEPEEYVVEEKLHIISKRVEAEPAEVTERQEKKIV 9563
Query: 314 HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTL-RVEPPSPPEGPPNPGPDGGKQD 372
+ A +EE + + PE P P +V PP PE P P P+
Sbjct: 9564 LKPKIPAKIEEPPPAKVPEAPKKIVPEKKVPAPVPKKEKVPPPKVPEEPKKPVPE----- 9618
Query: 373 GEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATS----EAPSAR 428
P K EE P P + E + + + EAP
Sbjct: 9619 ------KKVPPKVIKMEE----------PLPAKVTERHMQITQEEKVLVAVTKKEAPPKA 9662
Query: 429 DGPERSVPKEAEPTPPVL---PDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPST 485
PE PK A P VL P E+ PP E R+ + E+ + P+R
Sbjct: 9663 RVPEE--PKRAVPEEKVLKLKPKREEEPPAKVTE-FRKRVVKEEKVSIEAPKR------- 9712
Query: 486 APAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERA 545
P P + ++ + A + A E E D + P E
Sbjct: 9713 --EPQPIKEVTIMEEKERAYTLEEEAVSVQREEEYEEYE----EYDYKEFEEYEPTEEYD 9766
Query: 546 EAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGP 605
+ E ER E K V P P ++P + P A+
Sbjct: 9767 QYEE--YEEREYERYEEHEEYITEPEKPIPVKPVPEEPVP--TKP------KAPPAKV-- 9814
Query: 606 VWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQ--EAAAAPGT 663
+A ++ +P P+ KP P K+ E + ++ R+ Q E AA
Sbjct: 9815 --LKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPM 9872
Query: 664 REPCPAAQE--PAPSEDRNPFPVKLRSTSLSLKYRDGASQE--VKGVKRYSAEVR---LE 716
+ A+E P P ++ P PV++ L+ + A +E V V+ Y E +
Sbjct: 9873 KPKRVVAEEKVPVPRKEVAP-PVRVPEVPKELEPEEVAFEEEVVTHVEEYLVEEEEEYIH 9931
Query: 717 RSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPE----PLSSKPPLPRKPLLQ-SF 771
+ +EE P+ R P + K P+ P + P +P+KP +
Sbjct: 9932 EEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPV 9991
Query: 772 TLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAP-PWITVT 830
+P + PP A E K+P EK P+ + PPA P +P P + V
Sbjct: 9992 LIPKKEKPPPA--KVPEVPKKPVPEEKVPVPVPKKVEAPPAKV-PEVPKKPVPEKKVPVP 10048
Query: 831 RQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEP 870
K+ ++ PP + + + + E K VP++ + P
Sbjct: 10049 APKK---VEAPPAKVPEVPKKLIPEEK-KPTPVPKKVEAP 10084
Score = 31.2 bits (69), Expect = 4.9
Identities = 24/103 (23%), Positives = 37/103 (35%), Gaps = 5/103 (4%)
Query: 417 DPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEP 476
D AA + P PK PTPP + + + +P P R + + P
Sbjct: 242 DGAAGQQLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTP 301
Query: 477 ERI-----GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPP 514
+ ST+P S +P K + + + GP PP
Sbjct: 302 SPVRSVSPAARISTSPIRSVRSPLLMRKTQASTVATGPEVPPP 344
Score = 30.8 bits (68), Expect = 6.4
Identities = 19/63 (30%), Positives = 27/63 (42%), Gaps = 1/63 (1%)
Query: 431 PERSVPKEAEPTPPVLP-DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAP 489
PE P A P P +LP EEK PP E ++A + + +P+ + P
Sbjct: 8954 PEEIPPVVAPPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKP 9013
Query: 490 SPP 492
PP
Sbjct: 9014 PPP 9016
Score = 30.4 bits (67), Expect = 8.3
Identities = 29/126 (23%), Positives = 49/126 (38%), Gaps = 15/126 (11%)
Query: 238 SKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEER---PSSGQQDVAPDRGPE-- 292
S + RL R ++ S ++L T +E + E KP P+ R P+ + V P+ P
Sbjct: 8904 SVIARLEPRGEARSTAELYLTTKEIKLELKP--PDIPDSRVPIPTMPIRAVPPEEIPPVV 8961
Query: 293 --------PGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP 344
P P PPP + ++ + + + P E+ +P P P
Sbjct: 8962 APPIPLLLPTPEEKKPPPKRIEVTKKAVKKDAKKVVAKPKEMTPREEIVKKPPPPTTLIP 9021
Query: 345 ESAPTL 350
AP +
Sbjct: 9022 AKAPEI 9027
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 92.4 bits (228), Expect = 2e-18
Identities = 147/719 (20%), Positives = 240/719 (33%), Gaps = 110/719 (15%)
Query: 227 KLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVA 286
+L+ + QR + +L+S + + D E+E + EK SP R S
Sbjct: 125 ELKKEEIKQRQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSR------ 178
Query: 287 PDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP-- 344
+P P + RR R + S + P P + TPEL EP
Sbjct: 179 ----------SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSV 228
Query: 345 -----------ESAPTLRVEPPSPPEGPPNPGPD-GGKQDGEAPPAGPCAPATDKAEEVV 392
++ L+V P P P P P+ K++ E P + + K+
Sbjct: 229 KVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRT 288
Query: 393 CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKG 452
+ SP T + + +P R P R P P PP +
Sbjct: 289 RS----RSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPP----RHRR 340
Query: 453 PPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAA------S 506
P R + + + + R + P P + P+ + P+A+
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR 400
Query: 507 EGPAASPPLAAAESPP-----------VEPGPGSLDAEAAAPERPKAERAEAP-PAGAER 554
P A+PP SP V PG + + + + +P P +
Sbjct: 401 PSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460
Query: 555 AAPERKAERGGA-----ELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRS 609
E + ++GG ++ +++ + ++ G S E + ++G V R
Sbjct: 461 ELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRR 520
Query: 610 EAALDDLQGLPEPQHAKP-----GPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTR 664
P P+ + G R+ + P R+ SPA P + + P R
Sbjct: 521 RRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRR 580
Query: 665 EPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLER--SLTVL 722
P P + +PS R P++ R + R AS +R S +R S +
Sbjct: 581 TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPP 640
Query: 723 PKEEKCPL--------------GTAPALRGTR-----APSDQGKGKARPPEPLSSKPPLP 763
PK+ P+ G++P+ R TR P+ + RP P +S P P
Sbjct: 641 PKQRSSPVTKRRSPSLSSKHRKGSSPS-RSTREARSPQPNKRHSPSPRPRAPQTSSSPPP 699
Query: 764 RKPLLQSFTLPHQPAPPDAGPGER-----EPRKEPRTAEKRP--LRRGAEKSLPPAATGP 816
+ S Q P P R EP+K + A P +RR + + P
Sbjct: 700 VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 759
Query: 817 GADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQAD 875
A PAPP P Q P + P K+AK P P + +D
Sbjct: 760 AAKKPPAPP---------------SPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSD 803
Score = 88.6 bits (218), Expect = 3e-17
Identities = 155/707 (21%), Positives = 242/707 (34%), Gaps = 72/707 (10%)
Query: 222 SAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCT----PEEEENEEKPLL------- 270
S + K + +RSS +RR R+ S S T + P E+ E+ P L
Sbjct: 171 SPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKV 230
Query: 271 -EVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPG 329
E S +E S+ P P P P P P + + + + S
Sbjct: 231 KEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRS 290
Query: 330 EDPS-SRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKA 388
PS +RP + S R PSP P P PP +
Sbjct: 291 RSPSHTRPRRRHRSRSRSYSPRR--RPSPRR---RPSPRRRTPPRRMPPPPRHRRSRSPV 345
Query: 389 EEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAP--SARDGPERSVPKEAE-PTPPV 445
+ ++ ++ +PP+ P TS P + R P S P+ P+PP
Sbjct: 346 RRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA 405
Query: 446 LPDEEKGPPGPAPEPEREAE-----TEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKH 500
P K P P+ P R +G + GTE +P+P+P K L
Sbjct: 406 TPPP-KTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSE 464
Query: 501 RPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAP---ERPKAERAEAPPAGAER--- 554
AA+ + + S D+ +++ ERPK + G R
Sbjct: 465 SEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHS 524
Query: 555 ----AAPERKAERGGAELRGAKKFSVSS--CRARPRPGVSRPLERASGRLPLARSGPVWR 608
A+P + + RG ++ S S R R P + P R P P R
Sbjct: 525 PSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTP-----PPRR 579
Query: 609 SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668
+ + P P+ P ++ P R ASP P K + P R
Sbjct: 580 RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKR-RTASPPPPPKRRASPSPPPKRR---- 634
Query: 669 AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKC 728
+ P P + +P K RS SLS K+R G+S R + E R + P +
Sbjct: 635 VSHSPPPKQRSSPV-TKRRSPSLSSKHRKGSSP-----SRSTREARSPQ-----PNKRHS 683
Query: 729 PLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGERE 788
P A + + +P +G + P+ S P R S T + A P
Sbjct: 684 PSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASP---S 740
Query: 789 PRKEPRTAEKRPLRRGAEKSL--PPAATGPGADGQPAPPW---ITVTRQKRRGTLDQPPN 843
P+ R + R + E + PPA P P+ W + V + K PP
Sbjct: 741 PQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPR 800
Query: 844 QEDKPGA----RTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITP 886
D+ G + K + K+ K ++ ++ K+ + + +TP
Sbjct: 801 NSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTP 847
Score = 85.5 bits (210), Expect = 2e-16
Identities = 145/597 (24%), Positives = 209/597 (35%), Gaps = 141/597 (23%)
Query: 212 PAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLE 271
P E S ++ K K + +PR++ SK SR+++ S S P
Sbjct: 256 PKEPSPEKNSKKEKEKEKTRPRSRSRSK-----SRSRTRSRSPSHTRPRRRHRSRSR--S 308
Query: 272 VSPEERPSSGQQDVAPDRGPEPG---PPAPLPPPGGARARR----------ARLQHSSAL 318
SP RPS P R P P PP +PPP R R A L SS+
Sbjct: 309 YSPRRRPS-------PRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSS 361
Query: 319 TASVEEGGVPGEDP---SSRPATPELAEPESAPTLRVEPPSPPEGPP------------- 362
++S P + P SS P P ++P R PSPP PP
Sbjct: 362 SSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSN 421
Query: 363 ---------NPGPDGG---------KQDGEAPPAGPCAPATDKAEE----VVCAPEDVAS 400
+PG G K++ +P P ++EE + A + V
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQ 481
Query: 401 -------------------------PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
P + + G+ + S +PS R + +
Sbjct: 482 RRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS 541
Query: 436 P---KEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPP 492
P + P+PP P + P PAP P R R T P R T PS P P
Sbjct: 542 PRGRRRRSPSPP--PTRRRRSPSPAPPPRR-------RRTPTPPPRRRT-PSPPPRRRSP 591
Query: 493 APKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGA 552
+P+ ++ P + PP SPP P A+P P R P
Sbjct: 592 SPR---RYSPPIQRRYSPSPPPKRRTASPPPPP------KRRASPSPPPKRRVSHSPPPK 642
Query: 553 ERAAP--ERKAERGGAELRGAKKFSVSSCRAR-----------PRPGVSR------PLER 593
+R++P +R++ ++ R S S+ AR PRP + P+ R
Sbjct: 643 QRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRR 702
Query: 594 ASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKS 653
+ P R P S + + PEP+ K K A PQ S R +S S
Sbjct: 703 GASSSPQRRQSPS-PSTRPIRRVSRTPEPKKIK----KAASPSPQ-SVRRVSSSRSVSGS 756
Query: 654 PQEAAAAPGTREPCPAAQEPAPSEDRNP-FPV-KLRSTSLSLKYRDGASQEVKGVKR 708
P+ AA P P Q +PS + +P PV K +S + S + QE G K+
Sbjct: 757 PEPAAKKPPA--PPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKK 811
Score = 32.0 bits (71), Expect = 2.9
Identities = 58/274 (21%), Positives = 81/274 (29%), Gaps = 72/274 (26%)
Query: 232 PRNQRSSKM--RRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPD- 288
P QRSS + RR S + E +P SP RP + Q +P
Sbjct: 640 PPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPP 699
Query: 289 --RGPEPGPPAPLPPPGGAR----------------ARRARLQHSSALTASVEEGGVPGE 330
RG P P R A Q +++S G P
Sbjct: 700 VRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEP 759
Query: 331 DPSSRPATPELAEPES--------APTLRVEPPSPPEGPP-NPGPDGG------KQDGEA 375
PA P + +S P + + P+P PP N +GG K+D +
Sbjct: 760 AAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKH 819
Query: 376 PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSV 435
+E A A+ P AI TT + +P A
Sbjct: 820 KKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIAAATTTLAQEEPVA--------------- 864
Query: 436 PKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPE 469
APEP++E E+E E
Sbjct: 865 ---------------------APEPKKETESEAE 877
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 91.3 bits (225), Expect = 4e-18
Identities = 163/785 (20%), Positives = 261/785 (33%), Gaps = 147/785 (18%)
Query: 135 GPPPPPG-----GLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKV---SVVSP 186
G PP PG GL R D S + LP P L + T +K S + P
Sbjct: 97 GRPPDPGRPAQPGLSKSRTTDTFRSEQK--LPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 187 DHVSDSTVSARISD--NSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLS 244
+S+ + +S N P F ++S + + + K K+ K + + ++
Sbjct: 155 GFLSEVNALSAVSSVVNKFNP---FDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 245 SRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGG 304
+ + + P+++ PL + + SS Q + + P G P P
Sbjct: 212 QQQPPKPI------PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ-- 263
Query: 305 ARARRARLQHSSALTASVEEGGVPGEDPSSRPATPE--LAEPESAPTLRVEPPSPPEGPP 362
T + +P + +SRP T + + ES P PP P
Sbjct: 264 --------------TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 363 NPGPDGGKQDG-EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAAT 421
PG +Q G E GP P + + + P P G T PP P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGP 368
Query: 422 SEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGT 481
++ P+ + G E+ P +P P L PPG +G
Sbjct: 369 AKPPAQQTGSEK--PSSEQPGPKALAQ----PPG-----------------------VGK 399
Query: 482 EPSTAPAPSPPAPKSCLKHRPAAASEG---PAASPPLAAAESPPVEPGPGSLDAEAAAPE 538
P+ P P+ P + +P A G PA +P ++P +PGPG + A+ A P
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP--GPTKTPVQQPGPGKIPAQQAGPG 457
Query: 539 RPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRL 598
+ A++ ++ P + + +P P P + S +
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQ------------------QPGPAKPPPQQPGSAKP 499
Query: 599 PLARSGPVWRSEAALDDLQGLPEPQH---AKPGPRKLAERGPQDSGDRAASPAGPRKSPQ 655
P + G P PQ AKP P++ P +A P+ + SP
Sbjct: 500 PSQQPGST------------KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547
Query: 656 EAAAAPGTREPCPAA-----QEPAPSED-RNPFPVKLRSTSLSLKYRDGASQEVKGVKRY 709
+ +A T+ Q P S + P L T L V +
Sbjct: 548 KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF 607
Query: 710 SAEVRLERSLTVLPKEEKCPLGTAPALRGTR------APSDQGKGKARPPEPLSSKPPLP 763
+ + ++ L C P L + + G P P S +P L
Sbjct: 608 NTCTECQTTVCSL-----CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662
Query: 764 RKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAE-KSLPPAATGPGADGQP 822
P+ T + P + P+K+ A K+ L + E K PP P G P
Sbjct: 663 TAPV----TTTSAVSKSSPQPQQTSPKKD--AAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 823 APPWITVTRQKRRGTLDQPPNQE--DKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSK 880
+ QPP + KP S P +Q K P +P KQ V+
Sbjct: 717 S------------AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPT 763
Query: 881 SFLIT 885
+ L++
Sbjct: 764 TDLVS 768
Score = 82.8 bits (203), Expect = 1e-15
Identities = 141/652 (21%), Positives = 219/652 (33%), Gaps = 103/652 (15%)
Query: 256 TCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315
T P + KP + + E+PSS Q PGP A PPG +
Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQ----------PGPKALAQPPGVGK--------- 399
Query: 316 SALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGP---PNPGPDGGKQD 372
T + + G P + P+ + TP+ + + P P + P P PG +Q
Sbjct: 400 ---TPAQQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 373 G----EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSAR 428
G A GP P + P+ P G PP P +T + P +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQ 513
Query: 429 DGPERSVPKEAEPTPPVLPDEEKG-------PPGPAPEPEREAETEP--ERGAGTEPERI 479
GP + P++ T P P ++ G P PA +P + T+P + G+G +
Sbjct: 514 PGPAKPSPQQPGSTKP--PSQQPGSAKPSAQQPSPA-KPSAQQSTKPVSQTGSGKPLQPP 570
Query: 480 GTEPSTAPAPSPPAPKS---------CLKHRPAAASEGPAASPPLAAAESPPVEPGPGSL 530
PS PS PK+ L H P A+ P P
Sbjct: 571 TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLT 630
Query: 531 DAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRP 590
+ + + +RA ++P+ K + A ++ P+P + P
Sbjct: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS------KSSPQPQQTSP 684
Query: 591 LERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP 650
+ A A DL PEP+ KP P + P G +A P
Sbjct: 685 KKDA----------------APKQDLSKAPEPK--KPPP---LVKQPTLHGSPSAKAKQP 723
Query: 651 RKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYS 710
++ + AP P+ Q+ AP D P K+ + L A +
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA----------T 773
Query: 711 AEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQS 770
+ + S EEK T P + PS P SK +PR P S
Sbjct: 774 TKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFPPTGEKVSPFDSK-AIPR-PASDS 828
Query: 771 FTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVT 830
+ H P P G+++ +P ++ P ++ K P P G P PP T
Sbjct: 829 KIISH-PGPSSESKGQKQ--VDPVQKKEEP-KKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884
Query: 831 RQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSF 882
+ T Q P +++ +R G P+ +P + V K F
Sbjct: 885 AGQTVPTPQQSPKPQEQ--SRRFSLNLGSITDAPK--SQPTTPQETVTGKLF 932
Score = 70.9 bits (172), Expect = 6e-12
Identities = 172/775 (22%), Positives = 267/775 (34%), Gaps = 151/775 (19%)
Query: 273 SPEERPSSGQQDVAP----DRGPEPGPPAPL---PPPGG---ARARRARLQHSSALTASV 322
SP+ + +S ++D AP + PEP P PL P G A+A++ S + A
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Query: 323 EEGGVPGEDPSS-----RPATPELAEPES-------------APTLRVEPPSPPEGPPNP 364
+E VP E + +P P++ +P + P+ +V+ + + P
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 365 GPDGGKQDGEAPPAGP-CAPATDKAEEVVCAPEDVAS-PFPTAIPEGDTTPPETDPAATS 422
D K PP G +P KA + + S P P++ +G + DP
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK---QVDPVQKK 852
Query: 423 EAPSARDG-----PERSVPKEAEPTPP-VLPDEEKGPPGP--APEPEREAE--------- 465
E P P+ + PTPP P + P P +P+P+ ++
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912
Query: 466 TEPERGAGTEPERIGTEP----------------STAPAPSPPA---PKSCLKHRPAAAS 506
T+ + T P+ T STA P P + P + +K PA +
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 507 EGPAASPPLAAAESPPVE----PGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAE 562
+ PP + ++PP P A AA PKAE+A P +
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKD 1032
Query: 563 RGGAELRGAKKFSVSSCRARPRPGVSRPL---ERASGRLPLARSGPVWRSEAALDDLQGL 619
K + P+P + PL E G + + +L G
Sbjct: 1033 SKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
Query: 620 PEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDR 679
H L Q + RK P PA P S
Sbjct: 1093 NPTPHLTEIQEWLC-LNCQTQRAISGQLGDIRKMP-------------PAPSGPKAS--- 1135
Query: 680 NPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPK-EEKCPLGTAPALRG 738
P PV S+S + +VK VK+ EV+ E +L K +E + P +
Sbjct: 1136 -PMPVPTESSS----QKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190
Query: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEK 798
T ++ K + L K PLP + L +P + R K+P EK
Sbjct: 1191 TDQKQEESKLEKDKASALQEKKPLPEEKKL----IPEEEK-------IRSEEKKPLLEEK 1239
Query: 799 RPLRRGAEKSLPPAATG------------------PGADGQPAPPWITVTRQKR------ 834
+P +K LP A T +G+ AP + +Q +
Sbjct: 1240 KPTPED-KKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 835 -RGTLDQPPNQEDKPGARTLKSEP-----GKQAKVPERGQEPVKQADFVRSKSFLITPVK 888
GT P ++DK +T+K +P K +V E G+E ++ D S P
Sbjct: 1299 PSGTPQSLPKEDDKT-TKTIKEQPQPPCTAKPDQV-EPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 889 PAVDRKQGAKLNFKEGLQRGISLSHQNLAQSAVMMEKE-LHQLKRASYASTDQPS 942
P QG L+ GIS S + EK+ L LK+ S++ PS
Sbjct: 1357 P-----QG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 31/191 (16%)
Query: 301 PPGGARARRARLQHSSALTASVEEGG-------VPGEDPS--SRPATPELAEPESAPTLR 351
PP A + Q S+ S E G +P PS S PA P S+ +
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 352 VEPPSPPE--GPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEG 409
+PP PP PP P P PP P K + V +P A+P A+
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 410 D----------------TTPPETDPAATSEAPSA---RDGPERSVPKEA-EPTPPVLPDE 449
+ TT P P S PS PE S P A +P P LP
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Query: 450 EKGPPGPAPEP 460
+ P P+P
Sbjct: 2523 TQKPTDIHPKP 2533
Score = 39.7 bits (91), Expect = 0.014
Identities = 54/234 (23%), Positives = 73/234 (31%), Gaps = 46/234 (19%)
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPS-------------SGQQDVAPDRGPEPGPP 296
E LS T E +EKP ++ P PS S D++ P P PP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQL-PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP 2412
Query: 297 APLPP----------PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES 346
P PP P + L AS P D + T +
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Query: 347 APTLRVEPPSPPEGPPNPG--PDG----GKQDGEAPPAGPCAPATDKAEEVVCAPEDVAS 400
P R+ +PP PP P P G + + PP P P + P D+
Sbjct: 2473 LPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP-KPVIPQLPTTTQKPTDI-H 2530
Query: 401 PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPP 454
P PT + + +A + PS PT P+ P K P
Sbjct: 2531 PKPTGLSLTSSMTLNLVTSADYKLPS--------------PTSPLSPHSNKSSP 2570
Score = 37.7 bits (86), Expect = 0.052
Identities = 38/163 (23%), Positives = 55/163 (33%), Gaps = 14/163 (8%)
Query: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
E AS P+ P + P + P S + P P PP P PP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP---------PPPPPPPPPPPPPPP 2420
Query: 456 PAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPL 515
P P P T P+ + + P T P A + L+ S G + +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA-VTTLETTAVLRSNGLPVT-RI 2478
Query: 516 AAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPE 558
PPV P P S+ + RP+ + PP + P+
Sbjct: 2479 CTTAPPPVPPKPSSIPSGLVFTHRPEPSK---PPIAPKPVIPQ 2518
Score = 32.3 bits (72), Expect = 2.2
Identities = 41/168 (24%), Positives = 55/168 (32%), Gaps = 15/168 (8%)
Query: 628 GPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRN------- 680
G K A + P S ++ PA PR + ++ + P P P P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 681 PFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTV----LPKEEKCPLGTAPAL 736
P P + T L K AS + A LE + + LP C P
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV- 2486
Query: 737 RGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGP 784
PS G P SKPP+ KP++ Q P D P
Sbjct: 2487 --PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ-KPTDIHP 2531
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 91.3 bits (225), Expect = 4e-18
Identities = 163/785 (20%), Positives = 261/785 (33%), Gaps = 147/785 (18%)
Query: 135 GPPPPPG-----GLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKV---SVVSP 186
G PP PG GL R D S + LP P L + T +K S + P
Sbjct: 97 GRPPDPGRPAQPGLSKSRTTDTFRSEQK--LPGRSPSTISLKESKSRTDLKEEHKSSMMP 154
Query: 187 DHVSDSTVSARISD--NSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLS 244
+S+ + +S N P F ++S + + + K K+ K + + ++
Sbjct: 155 GFLSEVNALSAVSSVVNKFNP---FDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPL 211
Query: 245 SRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGG 304
+ + + P+++ PL + + SS Q + + P G P P
Sbjct: 212 QQQPPKPI------PKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQ-- 263
Query: 305 ARARRARLQHSSALTASVEEGGVPGEDPSSRPATPE--LAEPESAPTLRVEPPSPPEGPP 362
T + +P + +SRP T + + ES P PP P
Sbjct: 264 --------------TPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQP 309
Query: 363 NPGPDGGKQDG-EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAAT 421
PG +Q G E GP P + + + P P G T PP P
Sbjct: 310 TPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPP-AQPLGP 368
Query: 422 SEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGT 481
++ P+ + G E+ P +P P L PPG +G
Sbjct: 369 AKPPAQQTGSEK--PSSEQPGPKALAQ----PPG-----------------------VGK 399
Query: 482 EPSTAPAPSPPAPKSCLKHRPAAASEG---PAASPPLAAAESPPVEPGPGSLDAEAAAPE 538
P+ P P+ P + +P A G PA +P ++P +PGPG + A+ A P
Sbjct: 400 TPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAP--GPTKTPVQQPGPGKIPAQQAGPG 457
Query: 539 RPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRL 598
+ A++ ++ P + + +P P P + S +
Sbjct: 458 KTSAQQTGPTKPPSQLPGPAKPPPQ------------------QPGPAKPPPQQPGSAKP 499
Query: 599 PLARSGPVWRSEAALDDLQGLPEPQH---AKPGPRKLAERGPQDSGDRAASPAGPRKSPQ 655
P + G P PQ AKP P++ P +A P+ + SP
Sbjct: 500 PSQQPGST------------KPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPA 547
Query: 656 EAAAAPGTREPCPAA-----QEPAPSED-RNPFPVKLRSTSLSLKYRDGASQEVKGVKRY 709
+ +A T+ Q P S + P L T L V +
Sbjct: 548 KPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANF 607
Query: 710 SAEVRLERSLTVLPKEEKCPLGTAPALRGTR------APSDQGKGKARPPEPLSSKPPLP 763
+ + ++ L C P L + + G P P S +P L
Sbjct: 608 NTCTECQTTVCSL-----CGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLK 662
Query: 764 RKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAE-KSLPPAATGPGADGQP 822
P+ T + P + P+K+ A K+ L + E K PP P G P
Sbjct: 663 TAPV----TTTSAVSKSSPQPQQTSPKKD--AAPKQDLSKAPEPKKPPPLVKQPTLHGSP 716
Query: 823 APPWITVTRQKRRGTLDQPPNQE--DKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSK 880
+ QPP + KP S P +Q K P +P KQ V+
Sbjct: 717 S------------AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPT 763
Query: 881 SFLIT 885
+ L++
Sbjct: 764 TDLVS 768
Score = 82.8 bits (203), Expect = 1e-15
Identities = 141/652 (21%), Positives = 219/652 (33%), Gaps = 103/652 (15%)
Query: 256 TCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHS 315
T P + KP + + E+PSS Q PGP A PPG +
Sbjct: 359 TKPPAQPLGPAKPPAQQTGSEKPSSEQ----------PGPKALAQPPGVGK--------- 399
Query: 316 SALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGP---PNPGPDGGKQD 372
T + + G P + P+ + TP+ + + P P + P P PG +Q
Sbjct: 400 ---TPAQQPG--PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQA 454
Query: 373 G----EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSAR 428
G A GP P + P+ P G PP P +T + P +
Sbjct: 455 GPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGST-KPPPQQ 513
Query: 429 DGPERSVPKEAEPTPPVLPDEEKG-------PPGPAPEPEREAETEP--ERGAGTEPERI 479
GP + P++ T P P ++ G P PA +P + T+P + G+G +
Sbjct: 514 PGPAKPSPQQPGSTKP--PSQQPGSAKPSAQQPSPA-KPSAQQSTKPVSQTGSGKPLQPP 570
Query: 480 GTEPSTAPAPSPPAPKS---------CLKHRPAAASEGPAASPPLAAAESPPVEPGPGSL 530
PS PS PK+ L H P A+ P P
Sbjct: 571 TVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLT 630
Query: 531 DAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRP 590
+ + + +RA ++P+ K + A ++ P+P + P
Sbjct: 631 EVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVS------KSSPQPQQTSP 684
Query: 591 LERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP 650
+ A A DL PEP+ KP P + P G +A P
Sbjct: 685 KKDA----------------APKQDLSKAPEPK--KPPP---LVKQPTLHGSPSAKAKQP 723
Query: 651 RKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYS 710
++ + AP P+ Q+ AP D P K+ + L A +
Sbjct: 724 PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSA----------T 773
Query: 711 AEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQS 770
+ + S EEK T P + PS P SK +PR P S
Sbjct: 774 TKPDIPSSKVQSQAEEKT---TPPLKTDSAKPSQSFPPTGEKVSPFDSK-AIPR-PASDS 828
Query: 771 FTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVT 830
+ H P P G+++ +P ++ P ++ K P P G P PP T
Sbjct: 829 KIISH-PGPSSESKGQKQ--VDPVQKKEEP-KKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884
Query: 831 RQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSF 882
+ T Q P +++ +R G P+ +P + V K F
Sbjct: 885 AGQTVPTPQQSPKPQEQ--SRRFSLNLGSITDAPK--SQPTTPQETVTGKLF 932
Score = 70.9 bits (172), Expect = 6e-12
Identities = 172/775 (22%), Positives = 267/775 (34%), Gaps = 151/775 (19%)
Query: 273 SPEERPSSGQQDVAP----DRGPEPGPPAPL---PPPGG---ARARRARLQHSSALTASV 322
SP+ + +S ++D AP + PEP P PL P G A+A++ S + A
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPP 735
Query: 323 EEGGVPGEDPSS-----RPATPELAEPES-------------APTLRVEPPSPPEGPPNP 364
+E VP E + +P P++ +P + P+ +V+ + + P
Sbjct: 736 KEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPL 795
Query: 365 GPDGGKQDGEAPPAGP-CAPATDKAEEVVCAPEDVAS-PFPTAIPEGDTTPPETDPAATS 422
D K PP G +P KA + + S P P++ +G + DP
Sbjct: 796 KTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQK---QVDPVQKK 852
Query: 423 EAPSARDG-----PERSVPKEAEPTPP-VLPDEEKGPPGP--APEPEREAE--------- 465
E P P+ + PTPP P + P P +P+P+ ++
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSI 912
Query: 466 TEPERGAGTEPERIGTEP----------------STAPAPSPPA---PKSCLKHRPAAAS 506
T+ + T P+ T STA P P + P + +K PA +
Sbjct: 913 TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972
Query: 507 EGPAASPPLAAAESPPVE----PGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAE 562
+ PP + ++PP P A AA PKAE+A P +
Sbjct: 973 PPTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKD 1032
Query: 563 RGGAELRGAKKFSVSSCRARPRPGVSRPL---ERASGRLPLARSGPVWRSEAALDDLQGL 619
K + P+P + PL E G + + +L G
Sbjct: 1033 SKSLTAEPQKAVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGF 1092
Query: 620 PEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDR 679
H L Q + RK P PA P S
Sbjct: 1093 NPTPHLTEIQEWLC-LNCQTQRAISGQLGDIRKMP-------------PAPSGPKAS--- 1135
Query: 680 NPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPK-EEKCPLGTAPALRG 738
P PV S+S + +VK VK+ EV+ E +L K +E + P +
Sbjct: 1136 -PMPVPTESSS----QKTAVPPQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVT 1190
Query: 739 TRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEK 798
T ++ K + L K PLP + L +P + R K+P EK
Sbjct: 1191 TDQKQEESKLEKDKASALQEKKPLPEEKKL----IPEEEK-------IRSEEKKPLLEEK 1239
Query: 799 RPLRRGAEKSLPPAATG------------------PGADGQPAPPWITVTRQKR------ 834
+P +K LP A T +G+ AP + +Q +
Sbjct: 1240 KPTPED-KKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVAPKTVQEGKQPQTKMEGL 1298
Query: 835 -RGTLDQPPNQEDKPGARTLKSEP-----GKQAKVPERGQEPVKQADFVRSKSFLITPVK 888
GT P ++DK +T+K +P K +V E G+E ++ D S P
Sbjct: 1299 PSGTPQSLPKEDDKT-TKTIKEQPQPPCTAKPDQV-EPGKEKTEKEDDKSDTSSSQQPKS 1356
Query: 889 PAVDRKQGAKLNFKEGLQRGISLSHQNLAQSAVMMEKE-LHQLKRASYASTDQPS 942
P QG L+ GIS S + EK+ L LK+ S++ PS
Sbjct: 1357 P-----QG--LSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQESSPS 1404
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/191 (27%), Positives = 66/191 (34%), Gaps = 31/191 (16%)
Query: 301 PPGGARARRARLQHSSALTASVEEGG-------VPGEDPS--SRPATPELAEPESAPTLR 351
PP A + Q S+ S E G +P PS S PA P S+ +
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDIS 2402
Query: 352 VEPPSPPE--GPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEG 409
+PP PP PP P P PP P K + V +P A+P A+
Sbjct: 2403 AQPPPPPPPPPPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTL 2462
Query: 410 D----------------TTPPETDPAATSEAPSA---RDGPERSVPKEA-EPTPPVLPDE 449
+ TT P P S PS PE S P A +P P LP
Sbjct: 2463 ETTAVLRSNGLPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTT 2522
Query: 450 EKGPPGPAPEP 460
+ P P+P
Sbjct: 2523 TQKPTDIHPKP 2533
Score = 39.7 bits (91), Expect = 0.014
Identities = 54/234 (23%), Positives = 73/234 (31%), Gaps = 46/234 (19%)
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPS-------------SGQQDVAPDRGPEPGPP 296
E LS T E +EKP ++ P PS S D++ P P PP
Sbjct: 2354 EQLSTTYFTSGETFGQEKPASQL-PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP 2412
Query: 297 APLPP----------PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES 346
P PP P + L AS P D + T +
Sbjct: 2413 PPPPPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNG 2472
Query: 347 APTLRVEPPSPPEGPPNPG--PDG----GKQDGEAPPAGPCAPATDKAEEVVCAPEDVAS 400
P R+ +PP PP P P G + + PP P P + P D+
Sbjct: 2473 LPVTRICTTAPPPVPPKPSSIPSGLVFTHRPEPSKPPIAP-KPVIPQLPTTTQKPTDI-H 2530
Query: 401 PFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPP 454
P PT + + +A + PS PT P+ P K P
Sbjct: 2531 PKPTGLSLTSSMTLNLVTSADYKLPS--------------PTSPLSPHSNKSSP 2570
Score = 37.7 bits (86), Expect = 0.052
Identities = 38/163 (23%), Positives = 55/163 (33%), Gaps = 14/163 (8%)
Query: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
E AS P+ P + P + P S + P P PP P PP
Sbjct: 2370 EKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQP---------PPPPPPPPPPPPPPP 2420
Query: 456 PAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPL 515
P P P T P+ + + P T P A + L+ S G + +
Sbjct: 2421 PPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDA-VTTLETTAVLRSNGLPVT-RI 2478
Query: 516 AAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPE 558
PPV P P S+ + RP+ + PP + P+
Sbjct: 2479 CTTAPPPVPPKPSSIPSGLVFTHRPEPSK---PPIAPKPVIPQ 2518
Score = 32.3 bits (72), Expect = 2.2
Identities = 41/168 (24%), Positives = 55/168 (32%), Gaps = 15/168 (8%)
Query: 628 GPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRN------- 680
G K A + P S ++ PA PR + ++ + P P P P
Sbjct: 2368 GQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL 2427
Query: 681 PFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTV----LPKEEKCPLGTAPAL 736
P P + T L K AS + A LE + + LP C P
Sbjct: 2428 PPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPV- 2486
Query: 737 RGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGP 784
PS G P SKPP+ KP++ Q P D P
Sbjct: 2487 --PPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQ-KPTDIHP 2531
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 89.7 bits (221), Expect = 1e-17
Identities = 145/562 (25%), Positives = 190/562 (33%), Gaps = 72/562 (12%)
Query: 144 PAKRGEDAGMSSEDDG-LPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNS 202
P + AG + G P +P GT + + +P SAR +
Sbjct: 151 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP--------SARPRPPT 202
Query: 203 LAPVADFSYPAESSSCLDNSAAKHK------LQVKPRNQRSSKMRRLSSRAQSESLSDLT 256
P S +E S+ + AA+ + LQ SS LSS A+S + T
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 257 CTPEEEENEEKPL-LEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRA----- 310
++ KP L+ + + ++D AP GP P P P A +A
Sbjct: 263 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLP 322
Query: 311 RLQHSSALTASVEEGGVPGEDPSSRPATP-ELAEPE-SAPTLRVEPPSPPEGPPNPGPDG 368
HSS+LT + ATP LA P SAP PSPP PP+
Sbjct: 323 ATPHSSSLTCQL--------------ATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368
Query: 369 -GKQDGEA-------PPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGD---TTPPETD 417
G +A PP P A +A + P A P P A P T P+
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428
Query: 418 PAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKG--PPGPAPE----PEREAETEPERG 471
A A P S P +A +PP P PP AP P + P
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 488
Query: 472 AGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPA-ASPPLAAAESPPVE-PGPGS 529
P T P AP P P K P A PA A+PPL A SPP PG
Sbjct: 489 PPMSPS--ATPPPQAPPPLAAPPLQLAKPPPQAP---PALATPPLQALPSPPASFPGQAP 543
Query: 530 LDAEAAAPERPKAERA-EAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVS 588
A+ P P A +APP A + L+ ++ P PG
Sbjct: 544 FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR--------PPTPGPD 595
Query: 589 RPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPA 648
+ L LA P S + L G H+ E DSG + A
Sbjct: 596 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 655
Query: 649 GPRKSPQEAAAAPG--TREPCP 668
P + AA P +R P P
Sbjct: 656 SPPPDAELAACHPAAWSRGPAP 677
Score = 84.3 bits (207), Expect = 5e-16
Identities = 152/620 (24%), Positives = 203/620 (32%), Gaps = 93/620 (15%)
Query: 293 PGPPAPLPP----------PGGARARR-----------ARLQHSSALTASVEEGGVPGED 331
PG P P PP GA R+ A + S+ G +
Sbjct: 30 PGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN 89
Query: 332 PSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEV 391
P+SRP P E AP + P P P G+ G P P K +
Sbjct: 90 PASRP--PASGRGERAPPAKNTSPGPVSSP-------GRASGTTRPG----PLGQKGLRI 136
Query: 392 VCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEK 451
A E VA G T A ++ A GP P A E
Sbjct: 137 -SAEETVA--------RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 452 GPPGPAPEPEREAETE-PERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPA 510
G P PAP TE P + + E TEPS A P A RPA+ S +
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGL--QRPASRSLSSS 245
Query: 511 ASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERK------AERG 564
A+P + A S P G A + P +PK +A PP + P RK
Sbjct: 246 ATPLSSPARSGPSARGTPRAPAHPSQP-KPKGLQALRPP----QVTPPRKDAAPALGPLS 300
Query: 565 GAELRGAKKFSVSSCRARPR----PGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLP 620
+ L + +A P P S + + LPLA P +A LQ LP
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSP-----SAPPSLQTLP 355
Query: 621 EPQHAKPGPRKLAERGPQDSGDRAASPAGPR--------KSPQEAAAAPGTREPCPAAQE 672
P P + P + P+ P ++P A P P P A
Sbjct: 356 SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASP 415
Query: 673 P-APSEDRNP-FPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
P +P +P P L L + S V+ A + S T P + P
Sbjct: 416 PLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSAT--PPSQAPPS 473
Query: 731 GTAPALRGTRAP------SDQGKGKARPPEPLSS------KPPLPRKPLLQSFTLPHQPA 778
AP L+ +P S + P PL++ KPP P L + L P+
Sbjct: 474 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPS 533
Query: 779 PPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTL 838
PP + PG+ P + PL ++ PP P P+PP + RR
Sbjct: 534 PPASFPGQ-APFSPSASLPMSPLATPPPQA-PPVLAAPLLQVPPSPPASPTLQAPRRPPT 591
Query: 839 DQPPNQEDKPGARTLKSEPG 858
P P TL PG
Sbjct: 592 PGPDTSVSGP-RLTLALAPG 610
Score = 76.3 bits (186), Expect = 1e-13
Identities = 126/497 (25%), Positives = 173/497 (34%), Gaps = 56/497 (11%)
Query: 350 LRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEG 409
L PP P PP P + G A G P ++A + A + P A P
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGR-KPLAERAGGIGGAT--IPESAPRAGPTR 81
Query: 410 DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER----EAE 465
+PA S P++ G K P P P G P P ++ AE
Sbjct: 82 SAGTSSRNPA--SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139
Query: 466 TEPERGAGTE-PERIGTEP-----STAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAE 519
RG TE P+R ++ P P P+P + R AA +E P +A
Sbjct: 140 ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR-AAGTEVGLPRPAPSARP 198
Query: 520 SPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSC 579
PP E GP + A+ E + P+ A R R+ GG R A + SS
Sbjct: 199 RPPTE-GPRKSVSSAS-------EHSTTEPSPAAR----RRPSAGGGLQRPASRSLSSSA 246
Query: 580 RARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP--GP---RKLAE 634
P S P R + R P S P + AL Q P + A P GP LA
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 635 RGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLK 694
P + A P P +P ++ P P A P+PS P L+ +L
Sbjct: 307 PSPSAALQSQAPPTLP-ATPHSSSLTCQLATPLPLA-PPSPSA-----PPSLQ--TLPSP 357
Query: 695 YRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPE 754
SQ + L+ + + LP PL T P P+ PP
Sbjct: 358 PATPPSQATTSL----GSPTLQATHSFLPSPPLSPLATPPP---QAPPALALPPLQAPPS 410
Query: 755 PLSSKP------PLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKS 808
P +S P P P+ P + L P P P + P P + P ++
Sbjct: 411 PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA 470
Query: 809 LPPAATGPGADGQPAPP 825
PP+ P P+PP
Sbjct: 471 -PPSLAAPPLQVPPSPP 486
Score = 74.7 bits (182), Expect = 4e-13
Identities = 98/357 (27%), Positives = 120/357 (33%), Gaps = 58/357 (16%)
Query: 268 PLLEVSPEERPSSGQQDVAPDRGPEPGPP-APL--PPPGGARARRARLQHSSALTASVEE 324
PL P+ P+ + P PP +PL P P A L +
Sbjct: 388 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447
Query: 325 GGVPGEDPSSRPATPELAEPE------SAPTLRVEPPSPPEGPP-----NPGPDGGK--- 370
P P+S P +P P +AP L+V PPSPP PP P P
Sbjct: 448 VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV-PPSPPASPPMSPSATPPPQAPPPLA 506
Query: 371 ----QDGEAPPAGPCAPATDKAEEVVCAPEDVASPFP----TAIPEGD--TTPPETDPAA 420
Q + PP P A AT + + P P ++P T PP+ P
Sbjct: 507 APPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVL 566
Query: 421 TSEAPSARDGPERSVPKEAEPTPPVL-PDEE-KGP-------PGPAPEPEREAETE---- 467
+ P S +A PP PD GP PGP P P R +
Sbjct: 567 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 626
Query: 468 ----PERGAGTEPERI---GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAES 520
A + PE + + P A SPP PAA S GPA PPLA +
Sbjct: 627 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA--PPLAFRGA 684
Query: 521 P------PVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGA 571
P P GPGS D E E A P GA P GG GA
Sbjct: 685 PGAPLPWPPATGPGSADGLCTIYETEGPESA-TPAPGALDPGPS-PGTSGGKAAAGA 739
Score = 57.8 bits (138), Expect = 5e-08
Identities = 102/411 (24%), Positives = 137/411 (33%), Gaps = 56/411 (13%)
Query: 499 KHRPAAASEGPAASPPLAAAESPPVEPGPGS---------LDAEAAAPERPKAERA---- 545
K + AA+ PAA P PP P P L A A +P AERA
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 546 -EAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP----RPGVSRPLERASGRLPL 600
P A RA P R A S RA P PG RASG
Sbjct: 67 GATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG---T 123
Query: 601 ARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
R GP+ + + + + + A P++ A +P P + + A
Sbjct: 124 TRPGPLGQKGLRISAEETVARGK-ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182
Query: 661 PGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLE---- 716
GT P PAPS P R + S +R SA L+
Sbjct: 183 AGTEVGLP---RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 717 RSLTVLPKEEKCPLGTAPALRGT-RAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPH 775
RSL+ P + P+ RGT RAP+ + K + + L +PP T P
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQAL--RPP--------QVTPPR 289
Query: 776 QPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRR 835
+ A P GP P P + L+ A +LP Q A P
Sbjct: 290 KDAAPALGPLSSSPLATP--SPSAALQSQAPPTLPATPHSSSLTCQLATPLPLA------ 341
Query: 836 GTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSKSFLITP 886
PP+ P +TL S P A P + + + SFL +P
Sbjct: 342 -----PPSPSAPPSLQTLPSPP---ATPPSQATTSLGSPTLQATHSFLPSP 384
Score = 32.0 bits (71), Expect = 2.9
Identities = 36/122 (29%), Positives = 42/122 (34%), Gaps = 31/122 (25%)
Query: 724 KEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLP----------------RKPL 767
K +K G A RAP G P P S +PP P RKPL
Sbjct: 4 KRDKAKAGAAARTPAARAP-----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL 58
Query: 768 LQ------SFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAA-TGPGADG 820
+ T+P + P AGP R R RP G + PPA T PG
Sbjct: 59 AERAGGIGGATIPE--SAPRAGP-TRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVS 115
Query: 821 QP 822
P
Sbjct: 116 SP 117
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 89.4 bits (220), Expect = 2e-17
Identities = 135/586 (23%), Positives = 214/586 (36%), Gaps = 65/586 (11%)
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARR 309
E + T E E EEK E +E +++ PPA A+
Sbjct: 459 EQTEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKS 518
Query: 310 ARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPT-LRVEPPSPPEGPPNPGPDG 368
+ + S E P ++ + PA E+ PE A + + E SPPE +P +
Sbjct: 519 PVKEEAK----SPAEAKSPEKEEAKSPA--EVKSPEKAKSPAKEEAKSPPEA-KSPEKEE 571
Query: 369 GKQDGEA-PPAGPCAPATDKAEEVVCA--PEDVASPFPTAIPEGDTTPPETDPAATSEAP 425
K E P +PA ++A+ A PE SP + E +P E EA
Sbjct: 572 AKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSP----VKEEAKSPAEAKSPVKEEAK 627
Query: 426 SARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPE------RGAGTEPERI 479
S + +S K PT EE P A PE+E PE + PE+
Sbjct: 628 SPAE--VKSPEKAKSPT-----KEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEK- 679
Query: 480 GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPER 539
P A A SP KS +K A S A SP A+SP E + EA PE+
Sbjct: 680 AKSPVKAEAKSPEKAKSPVKEE--AKSPEKAKSPVKEEAKSP--EKAKSPVKEEAKTPEK 735
Query: 540 PKA---------ERAEAPPAG--AERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVS 588
K+ E+A++P + +PE K A KF ++ + V
Sbjct: 736 AKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFP-EKAKSPVKEEVK 794
Query: 589 RPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPA 648
P E+A L P E + + + P + P+++ + P + +PA
Sbjct: 795 SP-EKAKSPLKEDAKAP----EKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPA 849
Query: 649 GPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKR 708
P+ +E + P A +P E + P K + + + K + ++
Sbjct: 850 TPK--TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPE 907
Query: 709 YSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLL 768
A ++E PKE+ P + PS + K PE +K +KP
Sbjct: 908 KEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEE 967
Query: 769 QSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAAT 814
+ T E + +++ +T K P + AEK+ ++T
Sbjct: 968 KPKT-------------EAKAKEDDKTLSKEPSKPKAEKAEKSSST 1000
Score = 87.8 bits (216), Expect = 4e-17
Identities = 131/589 (22%), Positives = 213/589 (36%), Gaps = 65/589 (11%)
Query: 321 SVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGP 380
S +E + E T E+ E E + E EG +GG+++ ++PPA
Sbjct: 450 SEKETVIVEEQTEETQVTEEVTEEEEKEA-KEEEGKEEEGGEEEEAEGGEEETKSPPAEE 508
Query: 381 CAPATDKAEEVVCAPEDVASPFPTAIPEGDT--TPPETDPAATSEAPS---ARDGPERSV 435
A +A+ V E+ SP PE + +P E +++P+ A+ PE
Sbjct: 509 AASPEKEAKSPV--KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKS 566
Query: 436 PKEAEPTPPV---LPDEEKGP-------PGPAPEPER-EAETEPERGAGTEPERIGTEPS 484
P++ E P P++ K P P A PE+ ++ + E + E + E +
Sbjct: 567 PEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEA 626
Query: 485 TAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAER 544
+PA K+ + A S A SP A+SP P + AEA +PE+ K+
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSP--VKAEAKSPEKAKS-- 682
Query: 545 AEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSG 604
P AE +PE+ E + +K P ++ + + P
Sbjct: 683 ----PVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKS 738
Query: 605 PVWRSEAALDDLQGLPEPQHA-------KPGPRKLAERGPQDS-GDRAASPAGPR-KSPQ 655
PV + EA + PE P K R P D ++A SP KSP+
Sbjct: 739 PV-KEEAKSPEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPE 797
Query: 656 EAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRL 715
+A + P + P E ++P + + + +K ++E K E +
Sbjct: 798 KAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKK 857
Query: 716 ERSLTVLPK---------EEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKP 766
+ PK E+K P P A ++ + K + P P P
Sbjct: 858 DSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAP------ 911
Query: 767 LLQSFTLPHQPAPPDAGPGERE--PRKEPRTAE-KRPLRRGAEKSLPPAATGPGADGQPA 823
DA P E+ +KEP A+ K P + +K P +
Sbjct: 912 -------AKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKK 964
Query: 824 PPWITVTRQKRR---GTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQE 869
P T K + TL + P++ A S K +K PE+ E
Sbjct: 965 PEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATE 1013
Score = 85.1 bits (209), Expect = 3e-16
Identities = 124/496 (25%), Positives = 191/496 (38%), Gaps = 76/496 (15%)
Query: 415 ETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGT 474
E + A E + E + E E PV EE P A PE+E P
Sbjct: 490 EEEEAEGGEEETKSPPAEEAASPEKEAKSPV--KEEAKSPAEAKSPEKEEAKSPAEVKSP 547
Query: 475 EPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE----GPAASPPLAAAESPPVEPGPGSL 530
E + P+ A SPP KS K + +E A SP A+SP
Sbjct: 548 EKAK---SPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSP--------- 595
Query: 531 DAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRP 590
AEA +PE+ K+ E + AE +P ++ + AE++ +K + P ++
Sbjct: 596 -AEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKS 654
Query: 591 LERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP 650
E+ + P PV ++EA P+ AK P K + P ++A SP
Sbjct: 655 PEKEEAKSPEKAKSPV-KAEA--------KSPEKAK-SPVKAEAKSP----EKAKSPVKE 700
Query: 651 RKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYS 710
E A +P +E A S ++ PVK K + +E K ++
Sbjct: 701 EAKSPEKAKSP--------VKEEAKSPEKAKSPVK-EEAKTPEKAKSPVKEEAKSPEKAK 751
Query: 711 AEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRK-PLLQ 769
+ E++ T+ + K P PA R+P+D+ KA+ P K P K PL +
Sbjct: 752 SP---EKAKTL---DVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKE 805
Query: 770 SFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITV 829
P + P ++E K P E++P + K P A A PA P
Sbjct: 806 DAKAPEKEIP------KKEEVKSPVKEEEKP-QEVKVKEPPKKAEEEKA---PATP---K 852
Query: 830 TRQKRRGTLDQPPNQEDKPGARTLKSEPG----KQAKVPERGQEPVKQADFVRSKSFLIT 885
T +K+ ++ P +E K EP K++KV + +E K + T
Sbjct: 853 TEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE-------AEDKKKVPT 905
Query: 886 PVKPA---VDRKQGAK 898
P K A V+ K+ AK
Sbjct: 906 PEKEAPAKVEVKEDAK 921
Score = 80.1 bits (196), Expect = 9e-15
Identities = 124/550 (22%), Positives = 210/550 (38%), Gaps = 68/550 (12%)
Query: 232 PRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDV------ 285
P + +S + S + E+ S E+E + P SPE+ S +++
Sbjct: 505 PAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEA 564
Query: 286 -APDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEP 344
+P++ E PA + P A++ S A S E+ P ++ + PA
Sbjct: 565 KSPEK-EEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA------- 616
Query: 345 ESAPTLRVEPPSPPE-GPPNPGPDGGKQDGEAP-----PAGPCAPATDKAEEVVCA---- 394
E+ ++ E SP E P K++ ++P P A + +KA+ V A
Sbjct: 617 EAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKS 676
Query: 395 PEDVASPFPTAI--PEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKG 452
PE SP PE +P + + + +A S +S K P EE
Sbjct: 677 PEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPV-----KEEAK 731
Query: 453 PPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
P A P +E PE+ PE+ T +P PA + PA A S
Sbjct: 732 TPEKAKSPVKEEAKSPEK--AKSPEKAKTLDVKSPEAKTPAKEEA--RSPADKFPEKAKS 787
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP------PAGAERAAPERKAERGGA 566
P +SP P DA+A E PK E ++P P + P +KAE A
Sbjct: 788 PVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKA 847
Query: 567 -------ELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGL 619
E + +KK A P+P V E A + + V + +D + +
Sbjct: 848 PATPKTEEKKDSKKEEAPKKEA-PKPKVEEKKEPA---VEKPKESKVEAKKEEAEDKKKV 903
Query: 620 PEPQHAKPGPRKLAERG-PQDSGDRAASPAGPRKSPQEAAAAPGTREPC-PAAQEPAPSE 677
P P+ P ++ E P++ + A +K P +A A +EP PA ++ A E
Sbjct: 904 PTPEKEAPAKVEVKEDAKPKEKTEVA------KKEPDDAKA----KEPSKPAEKKEAAPE 953
Query: 678 DRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALR 737
++ K + K A ++ K + + ++ + E++ ++K + P +
Sbjct: 954 KKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKEPSKPKAEKAEKSSSTDQK---DSKPPEK 1010
Query: 738 GTRAPSDQGK 747
T + +GK
Sbjct: 1011 ATEDKAAKGK 1020
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 87.8 bits (216), Expect = 4e-17
Identities = 199/899 (22%), Positives = 284/899 (31%), Gaps = 187/899 (20%)
Query: 129 QCNVKMGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSL------LHD---------V 173
+C+ +G PP P LP G +G S+ P +P L LH
Sbjct: 46 RCSASIGQPPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPLHGKLESLHGCVQALLREPA 105
Query: 174 GPGTTIKVS-VVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNS--------AA 224
PG ++ + +H DS + R ++L F+ L + +
Sbjct: 106 QPGLWEQLGQLYESEH--DSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHTGSC 163
Query: 225 KHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPS--SGQ 282
+H+ +V P ++ + L + + P + E P+++ P S SG+
Sbjct: 164 QHRAKVLPPLEQVWNLLHLEHKRNYGAKRG---GPPVKRAAEPPVVQPVPPAALSGPSGE 220
Query: 283 QDVAPD----RG--------------------PEPGPPAPLPPPGGARARRARLQ----- 313
+ ++P RG P P PP P PPP A Q
Sbjct: 221 EGLSPGGKRRRGCNSEQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPG 280
Query: 314 -----HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSP---PEGPPNPG 365
H A +G P E R + P P AP PP P PP PG
Sbjct: 281 LWSTLHGDAWGPE-RKGSAPPERQEQRHSLPH-PYPYPAPAYTAHPPGHRLVPAAPPGPG 338
Query: 366 P--DGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTA----IPEGDTTPPETDPA 419
P G + G P P P +D E V +S P A +P + PP
Sbjct: 339 PRPPGAESHGCLPATRP--PGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGT 396
Query: 420 ATSEAPSARDG-------PERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGA 472
TS + S+ P +P P L G GP+ R+ P GA
Sbjct: 397 TTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRK----PFLGA 452
Query: 473 GTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPP----------LAAAESPP 522
+ P + P PP P+ P A +GPA E PP
Sbjct: 453 PAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPP 512
Query: 523 VEPGPGSLDAEAAAPERPKA------ERAEAPPAGAERAAPERKAERGG--AELRGAKKF 574
P P L P + + + PP + G + G F
Sbjct: 513 -RPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSF 571
Query: 575 SVSSCRARPRPGVSRPLERASGR-----LPLARSGPVWRSEAALDDLQGL---PEPQHAK 626
AR + RP A +PL + P + + G PE +
Sbjct: 572 PPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPR 631
Query: 627 PGPRKLAERGPQDSGDRAASPAGP-RKSPQEAAAAPG---TREPCPAAQEPAPSEDR--N 680
K E GP P GP K+PQ G R P P P ED+
Sbjct: 632 VSFPKTPEVGP-------GPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEE 684
Query: 681 PFPVKLRSTSLS--LKYRDGASQEVKGVKRYSAEVRLE-------RSLTVLPKEEKCPLG 731
P K+ L+ +K D + ++ + +++ A V + SL + P
Sbjct: 685 PAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTT 744
Query: 732 TAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGP------- 784
TAPA+ T + A E P LP P L F P QP PP P
Sbjct: 745 TAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLL 804
Query: 785 --------GER----------EPRKEP-RTAEKRPLRRGAEKSLPPAATGPGADGQPAP- 824
G++ R P T + P +LPP + P A G P P
Sbjct: 805 KSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPS 864
Query: 825 ------------PWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPERGQEPV 871
PW R++R G +E PG T P + P R + V
Sbjct: 865 ASSSSQFSTSGGPW---ARERRAG-------EEPVPGPMTPTQPPPPLSLPPARSESEV 913
Score = 66.2 bits (160), Expect = 1e-10
Identities = 137/629 (21%), Positives = 205/629 (32%), Gaps = 92/629 (14%)
Query: 294 GPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVE 353
GPP P PPP L H G S P TP S+ +
Sbjct: 510 GPPRPAPPP---------LPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGS 560
Query: 354 PPSPPEGP--------------PNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVA 399
S P GP P P P Q+ + PP P A A C
Sbjct: 561 HSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSG 620
Query: 400 S------PFP-TAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAE------PTP--- 443
S P P + P+ P P S+AP +P PTP
Sbjct: 621 SFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVPPGVGELPARGPRLFDFPPTPLED 680
Query: 444 --------PVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTA---PAPSPP 492
+LPD E R+ E + + AG P+ EP + P P+
Sbjct: 681 QFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFASLQSPFPTDT 740
Query: 493 APKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGA 552
AP + PA A + A + P +L + P + + PP
Sbjct: 741 APTTTA---PAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPP 797
Query: 553 ERAAPERKAERGGAELRGAKK-FSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEA 611
A K+ + L G K + + RPG + + G A + P +
Sbjct: 798 PSPASLLKSL--ASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALP---PTS 852
Query: 612 ALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP----RKSPQEAAAAP--GTRE 665
A QG P+P + S + ++ GP R++ +E P T+
Sbjct: 853 AAPSAQGSPQPSAS--------------SSSQFSTSGGPWARERRAGEEPVPGPMTPTQP 898
Query: 666 PCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYS-AEVRLERSLTVLPK 724
P P + PA SE + +L + A+ V A+ ER L P
Sbjct: 899 PPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTERLLP--PA 956
Query: 725 EEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKP----LLQSFTLPHQPAPP 780
+ K G A+ G+ + K + K + R+P +P + +
Sbjct: 957 QAKEEAGGVAAVSGSCKRRQKEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRR 1016
Query: 781 DAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAA----TGPGADGQPAPPWITVTRQKRRG 836
G + + + + RP GA K+ PP A + P QP PP +V +K R
Sbjct: 1017 VLGNLDLQSEEIQGREKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKARE 1076
Query: 837 TLDQPP--NQEDKPGARTLKSEPGKQAKV 863
PP ++ D R+L P K+ K+
Sbjct: 1077 EAPGPPGVSRADMLKLRSLSEGPPKELKI 1105
Score = 56.2 bits (134), Expect = 1e-07
Identities = 134/624 (21%), Positives = 210/624 (33%), Gaps = 117/624 (18%)
Query: 136 PPPPPGGLPAKRGEDAGMSSEDDGLPRS-PPEMSLLHDVGPGTTIKVSVVSPDHVSDSTV 194
PP PP + ++G S P S PP L + P +P
Sbjct: 543 PPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQ------- 595
Query: 195 SARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRR----------LS 244
D L P+ PA SSC N++ + PR + S LS
Sbjct: 596 -----DPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLS 650
Query: 245 SR------------AQSESLSDLTCTPEEEENEEKPLLEVSPE----------ERPSSGQ 282
A+ L D TP E++ EE ++ P+ E +
Sbjct: 651 KAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEE 710
Query: 283 QDVAPDRGPEPGPP---------APLPPPGGARARRARLQHSSALTASVEEGGVPGEDPS 333
+ + G P PP +P P + ++ T + E+
Sbjct: 711 EQQQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKK 770
Query: 334 SRPATPELAEPESAPTLRVEPPSPPEGPPNPGPD--------GGKQDGEAPPAGPCAPAT 385
PA P P + PPS P+ PP P P +G+ C T
Sbjct: 771 PPPALPP-----PPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQK----YCYRGT 821
Query: 386 DKAEEVVCAPEDVA--SPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTP 443
A P SP P P G T P TS APSA+ P+ S ++ +
Sbjct: 822 GAAVSTRPGPLPTTQYSPGP---PSGATALP-----PTSAAPSAQGSPQPSASSSSQFST 873
Query: 444 PVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSC--LKHR 501
P + G P P T+P P R +E ++C L R
Sbjct: 874 SGGPWARERRAGEEPVPGPMTPTQPPPPLSLPPARSESE------VLEEISRACETLVER 927
Query: 502 PAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKA 561
++ PA P+ AE P + G L A A E EA A + +R+
Sbjct: 928 VGRSATDPA--DPVDTAE--PADSGTERLLPPAQAKE-------EAGGVAAVSGSCKRRQ 976
Query: 562 ERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRS-EAALDDLQGLP 620
+ E R ++ S RPR G + +A ++P +S V + + +++QG
Sbjct: 977 KEHQKEHRRHRRACKDSVGRRPREGRA----KAKAKVPKEKSRRVLGNLDLQSEEIQG-- 1030
Query: 621 EPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRN 680
+ ++P ++ P + ++PA + +A+ PG + + P P
Sbjct: 1031 -REKSRPDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKK---AREEAPGPPGVSR 1086
Query: 681 PFPVKLRSTSLSLKYRDGASQEVK 704
+KLRS S +G +E+K
Sbjct: 1087 ADMLKLRSLS------EGPPKELK 1104
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 87.0 bits (214), Expect = 7e-17
Identities = 187/713 (26%), Positives = 226/713 (31%), Gaps = 188/713 (26%)
Query: 271 EVSPE-ERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPG 329
E P+ R S G Q V RG EPGPP P G A A Q + G PG
Sbjct: 354 EAGPQGPRGSEGPQGV---RG-EPGPPGPAGAAGPAGNPGADGQPGAK-----GANGAPG 404
Query: 330 EDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQD----GEAPPAGPCAPAT 385
+ P P P S P PP P PG G K D GE P G P
Sbjct: 405 I--AGAPGFPGARGP-SGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPG 461
Query: 386 DKAEEVVCAPEDVASPFPTAIP--------EGDTTPPETDPAATSEAPSARDG------P 431
EE P PT +P G P D A + P+ G P
Sbjct: 462 PAGEEGKRGAR--GEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGP 519
Query: 432 ERSVPKEAEPTPPVLP--------------DEEKGPPGPAPEPEREAETEP--------- 468
+ S + P LP D + GPPGPA + R P
Sbjct: 520 KGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGV 579
Query: 469 -----ERGAGTEPERIGTEPSTAP--------------APSPPAPKSCLKHRPAAASEGP 509
+GA EP + G P A PP P R +GP
Sbjct: 580 MGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGER---GEQGP 636
Query: 510 AASPPLAAAESPPVEPG----------PGSLDAEAAAPER-----PKAERAEAPPAGA-- 552
A SP P PG PG L A + R P + PP A
Sbjct: 637 AGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696
Query: 553 --ERAAPERKAERGGAELRGAKKFSVSSCRARPRPGV-SRPLERASGRLPLAR-----SG 604
AP +G A GA ++ PG+ P ER + LP + +G
Sbjct: 697 RGANGAPGNDGAKGDAGAPGAP-------GSQGAPGLQGMPGERGAAGLPGPKGDRGDAG 749
Query: 605 PVWR-SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGT 663
P D ++GL P PGP P D G+ + P+GP P A APG
Sbjct: 750 PKGADGSPGKDGVRGLTGP-IGPPGP----AGAPGDKGE--SGPSGP-AGPTGARGAPGD 801
Query: 664 R----EPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSL 719
R P PA P D P GA E A+
Sbjct: 802 RGEPGPPGPAGFAGPPGADGQP----------------GAKGEPGDA---GAKGDAGPPG 842
Query: 720 TVLPKEEKCPLGT--APALRGTRA----PSDQG----KGKARPPEPLSSKPPLPRKPLLQ 769
P P+G AP +G R P G G+ PP P + P
Sbjct: 843 PAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGP-------- 894
Query: 770 SFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLP-----------PAATGP-G 817
P PP GP +E K PR E P R E P P A GP G
Sbjct: 895 -------PGPP--GPAGKEGGKGPR-GETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAG 944
Query: 818 ADGQPAPPWITVTRQKRRGTLDQPPNQEDK--PGARTLKSEPGKQAKVPERGQ 868
A G P P I +RG + P + ++ PG EPGKQ G+
Sbjct: 945 APGTPGPQGIA----GQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGE 993
Score = 71.2 bits (173), Expect = 4e-12
Identities = 132/472 (27%), Positives = 153/472 (32%), Gaps = 103/472 (21%)
Query: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
P ++ P L+ P ER ++G DRG + GP PG R L
Sbjct: 715 PGAPGSQGAPGLQGMPGERGAAGLPGPKGDRG-DAGPKGADGSPGKDGVR--------GL 765
Query: 319 TASVEE---GGVPGEDPSSRPATPELAEP---ESAPTLRVEPPSPPE----GPPN----- 363
T + G PG+ S P+ P A P AP R EP P GPP
Sbjct: 766 TGPIGPPGPAGAPGDKGESGPSGP--AGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQP 823
Query: 364 -----PGPDGGKQD----GEAPPAGPCAPATDKAEEVVCAPEDVASP-----FPTAIPEG 409
PG G K D G A PAGP P + A P FP A G
Sbjct: 824 GAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAA--G 881
Query: 410 DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDE--EKGPPGPAPEPEREAETE 467
PP A P G E E P P E GPPGPA E
Sbjct: 882 RVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADG 941
Query: 468 PERGAGTE-PERIGTEPSTAPAPSP---------PAPKSCL-KHRPAAAS-----EGPAA 511
P GT P+ I + P P P K P+ AS GP
Sbjct: 942 PAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGASGERGPPGPMG 1001
Query: 512 SPPLAAAESPPVEPGPGSLDAEAAAPERP-----KAERAEAPPAGAERA--APERKAERG 564
P LA PP E G +P R K +R E PAG A AP G
Sbjct: 1002 PPGLAG---PPGESGREGAPGAEGSPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVG 1058
Query: 565 GAELRGAKKFSVSSCRARPRP-GVSRPLERASGRLPLARSGPVW-------------RSE 610
A G R P G + P+ R P GP +
Sbjct: 1059 PAGKSGD--------RGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQGDRGIKGH 1110
Query: 611 AALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPG 662
LQG P P P E+GP A+ PAGPR P +A APG
Sbjct: 1111 RGFSGLQGPPGP------PGSPGEQGPSG----ASGPAGPR-GPPGSAGAPG 1151
Score = 65.5 bits (158), Expect = 2e-10
Identities = 119/481 (24%), Positives = 154/481 (32%), Gaps = 98/481 (20%)
Query: 273 SPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDP 332
SP ++ ++G + D GP GP P PPG R + L G PG
Sbjct: 101 SPTDQETTGVEGPKGDTGPR-GPRGPAGPPG-----RDGIPGQPGLPGPPGPPGPPGPPG 154
Query: 333 SSRPATPELA---EPESAPTLRVEPP---SPPEGPPNPGPDGGKQDGEAPPAGPCAPATD 386
P+L+ + +S + V P S P G P P G Q + PP P P
Sbjct: 155 LGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPG-- 212
Query: 387 KAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVL 446
+ P P G D A GP P L
Sbjct: 213 -----------ASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGL 261
Query: 447 P-----------DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTE--PSTAPAPSPPA 493
P D KG GPA P+ E + E GA P ++G P P P
Sbjct: 262 PGMKGHRGFSGLDGAKGDAGPA-GPKGEPGSPGENGA---PGQMGPRGLPGERGRPGAPG 317
Query: 494 PKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAA-----APERPKAERAEAP 548
P + A + GP P PP PG EA E P+ R E
Sbjct: 318 PAGARGNDGATGAAGP---PGPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPG 374
Query: 549 PAGAERAA-----------PERKAERGGAELRGAKKFSVSSCRARPR-PGVSRPLERASG 596
P G AA P K G + GA F + + P+ PG + SG
Sbjct: 375 PPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSG 434
Query: 597 R--LPLARSGPVWRSEAALDDLQGLPEP--------QHAKPGPRKL----AERGPQDS-- 640
P ++ + E +QG P P +PGP L ERG S
Sbjct: 435 EPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRG 494
Query: 641 --------------GDRAA-SPAGPRKSPQEA-----AAAPGTREPCPAAQEPAPSEDRN 680
G+R + PAGP+ SP EA A PG + + P P
Sbjct: 495 FPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTG 554
Query: 681 P 681
P
Sbjct: 555 P 555
Score = 56.2 bits (134), Expect = 1e-07
Identities = 82/321 (25%), Positives = 101/321 (31%), Gaps = 70/321 (21%)
Query: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
P +E + P E P RP E GPP P P G
Sbjct: 900 PAGKEGGKGPRGETGPAGRPG------------EVGPPGPPGPAG--------------- 932
Query: 319 TASVEEGGVPGED-PSSRPATPE---LAEPESA---PTLRVEPPSPPEGPPNPGPDGGKQ 371
E G PG D P+ P TP +A P R E P G P P + GKQ
Sbjct: 933 -----EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFP--GLPGPSGEPGKQ 985
Query: 372 -----DGEAPPAGP------CAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAA 420
GE P GP P + E AP SP P ET PA
Sbjct: 986 GPSGASGERGPPGPMGPPGLAGPPGESGREG--APGAEGSPGRDGSPGAKGDRGETGPAG 1043
Query: 421 TSEAPSARDGP----------ERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPER 470
AP A P +R A P PV P +GP GP + ET +
Sbjct: 1044 PPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQGPRGDKGETGEQG 1103
Query: 471 GAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSL 530
G + R + PP P + + + GPA + P + G L
Sbjct: 1104 DRGIKGHR-----GFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGAPGKDGLNGL 1158
Query: 531 DAEAAAPERPKAERAEAPPAG 551
P P+ +A P G
Sbjct: 1159 PG-PIGPPGPRGRTGDAGPVG 1178
Score = 44.3 bits (103), Expect = 6e-04
Identities = 58/206 (28%), Positives = 69/206 (33%), Gaps = 31/206 (15%)
Query: 259 PEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSAL 318
P E E P E SP S G + DRG E GP P PG A
Sbjct: 1009 PGESGREGAPGAEGSPGRDGSPGAKG---DRG-ETGPAGPPGAPGAPGA----------- 1053
Query: 319 TASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQD------ 372
V G G+ + PA P A P R P+ P+GP + G+Q
Sbjct: 1054 PGPVGPAGKSGDRGETGPAGP--AGPVGPVGAR--GPAGPQGPRGDKGETGEQGDRGIKG 1109
Query: 373 --GEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDG 430
G + GP P E+ P + P P G P D P G
Sbjct: 1110 HRGFSGLQGPPGPPGSPGEQ---GPSGASGPAGPRGPPGSAGAPGKDGLNGLPGPIGPPG 1166
Query: 431 PERSVPKEAEPTPPVLPDEEKGPPGP 456
P R +A P P P GPPGP
Sbjct: 1167 P-RGRTGDAGPVGPPGPPGPPGPPGP 1191
Score = 32.0 bits (71), Expect = 2.9
Identities = 34/136 (25%), Positives = 47/136 (34%), Gaps = 18/136 (13%)
Query: 733 APALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKE 792
AP +G + P + P EP +S P PR P P PP + E K
Sbjct: 195 APGPQGFQGPPGE------PGEPGASGPMGPRGP----------PGPPGKNGDDGEAGKP 238
Query: 793 PRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGART 852
R E+ P + LP A PG G + + K P + PG
Sbjct: 239 GRPGERGPPGPQGARGLPGTAGLPGMKGHRG--FSGLDGAKGDAGPAGPKGEPGSPGENG 296
Query: 853 LKSEPGKQAKVPERGQ 868
+ G + ERG+
Sbjct: 297 APGQMGPRGLPGERGR 312
Score = 31.2 bits (69), Expect = 4.9
Identities = 29/104 (27%), Positives = 34/104 (32%), Gaps = 25/104 (24%)
Query: 288 DRGPE--PGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSR---PATPELA 342
++GP GP P PPG A G PG+D + P P
Sbjct: 1128 EQGPSGASGPAGPRGPPGSA--------------------GAPGKDGLNGLPGPIGPPGP 1167
Query: 343 EPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATD 386
+ V PP PP P PGP D P P A D
Sbjct: 1168 RGRTGDAGPVGPPGPPGPPGPPGPPSAGFDFSFLPQPPQEKAHD 1211
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 86.7 bits (213), Expect = 1e-16
Identities = 74/292 (25%), Positives = 104/292 (35%), Gaps = 23/292 (7%)
Query: 278 PSSGQQDVAPDRGPEP-GPPAPL----PPPGGARARRARLQHSSALTASVEEGGVPGEDP 332
P Q P G +P GPP P PPP G R+ +GG + P
Sbjct: 135 PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP 194
Query: 333 SSRPATPELAEPESAPTLR-VEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEV 391
P P+ P+ + PP P+GPP P D Q +PP P P +
Sbjct: 195 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP-PQGDNKSQSARSPPGKPQGPPPQGGNQP 253
Query: 392 VCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPE----RSVPKEAEPTPPVLP 447
P P P+G P P + P + G + RS P + + PP
Sbjct: 254 QGPPPPPGKP-QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGG 312
Query: 448 DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE 507
++ +GPP P +P+ P G +P+ P P P P+ K R A +
Sbjct: 313 NQPQGPPPPPGKPQ-----GPPPQGGNKPQ----GPPPPGKPQGPPPQGGSKSRSARSPP 363
Query: 508 GPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPER 559
G PP +P P P P+ P A + + PP + P R
Sbjct: 364 GKPQGPPQQEGNNPQGPPPPAG--GNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Score = 84.0 bits (206), Expect = 6e-16
Identities = 107/429 (24%), Positives = 150/429 (34%), Gaps = 57/429 (13%)
Query: 251 SLSDLTCTPEEEENEEKP-LLEVSPEERPSSG----QQDVAPDRGPEPGPP-------AP 298
+LS E+ EE P L+ +P+ P G Q +P P+ PP P
Sbjct: 12 ALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGP 71
Query: 299 LPPPGGARA--RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAP----TLRV 352
PPPG + + + +G P D S P +P +P+ P
Sbjct: 72 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPP-GKPQGPPPQGGNQPQ 130
Query: 353 EPPSPPEGPPNPGPDGG-KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDT 411
PP PP P P P GG K G PP P P + +S P P+G
Sbjct: 131 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN------KSRSSRSPPGKPQGPP 184
Query: 412 TPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERG 471
P P GP + + PP P + +GPP + A + P +
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQGPPPQGDNKSQSARSPPGKP 242
Query: 472 AGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLD 531
G P+ G +P P P P P+ P P PP + PP + G S
Sbjct: 243 QGPPPQG-GNQPQ-GPPPPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPPQGGSKSRS 296
Query: 532 AEAAAPERPKAERAEAPPAGAE--RAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSR 589
+ + P +P+ PP G + P + G +G K + P PG +
Sbjct: 297 SR-SPPGKPQG----PPPQGGNQPQGPPPPPGKPQGPPPQGGNK-----PQGPPPPGKPQ 346
Query: 590 -PLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP-GPRKLAERGPQD-SGDRAAS 646
P + + ARS P QG P+ + P GP A PQ A
Sbjct: 347 GPPPQGGSKSRSARSPP--------GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQ 398
Query: 647 PAGPRKSPQ 655
P GP + PQ
Sbjct: 399 PQGPPRPPQ 407
Score = 84.0 bits (206), Expect = 6e-16
Identities = 92/369 (24%), Positives = 132/369 (35%), Gaps = 44/369 (11%)
Query: 324 EGGVPGEDPSSRPATPELAEPESAPTLRVEPPSP--PEGPPNPGPDGGKQDGEAPPAGPC 381
+GG + P S P P+ P+ + PP P P+GPP G G K G PP P
Sbjct: 42 QGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQ 99
Query: 382 APAT--DKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEA 439
P DK+ +P P P+G P P GP +
Sbjct: 100 GPPPQGDKSR----SPRS-----PPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 150
Query: 440 EPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLK 499
+ PP P + +GPP R + + P + G P+ G +P P P P P+
Sbjct: 151 QGPPP--PGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG-GNQPQ-GPPPPPGKPQG--- 203
Query: 500 HRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAE--RAAP 557
P P PP + PP + G + + P +P+ PP G + P
Sbjct: 204 -PPPQGGNKPQGPPPPGKPQGPPPQ-GDNKSQSARSPPGKPQG----PPPQGGNQPQGPP 257
Query: 558 ERKAERGGAELRGAKKFSVSSCRARPRPGVSR-PLERASGRLPLARSGPVWRSEAALDDL 616
+ G +G K + P PG + P + + +RS P +
Sbjct: 258 PPPGKPQGPPPQGGNK-----PQGPPPPGKPQGPPPQGGSKSRSSRSPP---GKPQGPPP 309
Query: 617 QGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRK----SPQEAAAAPGTREPCPAAQE 672
QG +PQ P P K + P G++ P P K PQ + + R P Q
Sbjct: 310 QGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQG 368
Query: 673 PAPSEDRNP 681
P E NP
Sbjct: 369 PPQQEGNNP 377
Score = 79.3 bits (194), Expect = 2e-14
Identities = 116/502 (23%), Positives = 153/502 (30%), Gaps = 139/502 (27%)
Query: 330 EDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQ-DGEAPPAG-PCAPATDK 387
E PS P+ A P+ + PPSPP P P P GG Q G PP G P P
Sbjct: 27 ESPSLIAGNPQGAPPQGGNKPQ-GPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQG 85
Query: 388 AEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLP 447
+ P+ P P P+G PP+ D + + +P P + + PP
Sbjct: 86 GNK----PQ---GPPPPGKPQGP--PPQGDKSRSPRSP----------PGKPQGPPPQGG 126
Query: 448 DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE 507
++ +GPP P +P+ P G +P+ P P P P+ K R + +
Sbjct: 127 NQPQGPPPPPGKPQG-----PPPQGGNKPQG----PPPPGKPQGPPPQGDNKSRSSRSPP 177
Query: 508 GPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAE 567
G PP P P P P + P G + P + G
Sbjct: 178 GKPQGPPPQGGNQPQGPPPP------------PGKPQGPPPQGGNKPQGPPPPGKPQGPP 225
Query: 568 LRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP 627
+G K S AR PG + G P QG P P
Sbjct: 226 PQGDNK----SQSARSPPGKPQGPPPQGGNQP-----------------QGPPPPPGKPQ 264
Query: 628 GPRKLAERGPQDSGDRAASPAGPRKS----PQEAAAAPGTREPCPAAQEPAPSEDRNPFP 683
GP P G++ P P K PQ + + +R P Q P P
Sbjct: 265 GP-------PPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQ------- 310
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPS 743
G +Q P G P + P
Sbjct: 311 --------------GGNQ---------------------------PQGPPPPPGKPQGPP 329
Query: 744 DQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRR 803
QG K + P P P KP Q PP G R R P + P +
Sbjct: 330 PQGGNKPQGPPP-------PGKP---------QGPPPQGGSKSRSARSPPGKPQGPPQQE 373
Query: 804 GAEKSLPPAATGPGADGQPAPP 825
G PP G APP
Sbjct: 374 GNNPQGPPPPAGGNPQQPQAPP 395
Score = 60.8 bits (146), Expect = 6e-09
Identities = 53/227 (23%), Positives = 76/227 (33%), Gaps = 20/227 (8%)
Query: 278 PSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPA 337
P G + P P PG P PP G +++ AR + G P + P P
Sbjct: 206 PQGGNKPQGP---PPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP-QGPPPPPG 261
Query: 338 TPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQD--GEAPPAGPCAPATDKAEEVVCAP 395
P+ P+ + + P PP P P P GG + +PP P P + P
Sbjct: 262 KPQGPPPQGGN--KPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPP 319
Query: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
P P+G P P + P + G + + P P +E P
Sbjct: 320 PPPGKPQGPP-PQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQ 378
Query: 456 PAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRP 502
P P AG P++ P+ P P P+ RP
Sbjct: 379 GPPPP-----------AGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
Score = 33.9 bits (76), Expect = 0.75
Identities = 29/96 (30%), Positives = 38/96 (39%), Gaps = 4/96 (4%)
Query: 776 QPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRR 835
Q APP G + P P + P + G + PP G G P
Sbjct: 37 QGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGNKPQGPPPP 95
Query: 836 GTLDQPPNQEDKPGARTLKSEPGK-QAKVPERGQEP 870
G PP Q DK +R+ +S PGK Q P+ G +P
Sbjct: 96 GKPQGPPPQGDK--SRSPRSPPGKPQGPPPQGGNQP 129
Score = 31.6 bits (70), Expect = 3.7
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 2/47 (4%)
Query: 131 NVKMGPPPP--PGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGP 175
N GPPPP P G P + G + + G P+ PP+ + GP
Sbjct: 334 NKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGP 380
Score = 31.2 bits (69), Expect = 4.9
Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 2/47 (4%)
Query: 131 NVKMGPPPP--PGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGP 175
N GPPPP P G P + G + S G P+ PP GP
Sbjct: 272 NKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP 318
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 84.7 bits (208), Expect = 4e-16
Identities = 117/449 (26%), Positives = 141/449 (31%), Gaps = 78/449 (17%)
Query: 278 PSSGQQDVAPDRGP------------EPGPPAPLPP--PGGARARRARL----QHSSALT 319
P+ G AP+ P PGPP+P P P G A+L + S+
Sbjct: 78 PAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSC 137
Query: 320 ASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAG 379
A V P PA P +A R P P P PGP GK PAG
Sbjct: 138 APVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK------PAG 191
Query: 380 PCAPATDKAEEVVCAPEDVASPFPTAIPEGDT----------------TPPETDPAA--T 421
P A T + A+P + + G TPP AA
Sbjct: 192 PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPA 251
Query: 422 SEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGT 481
APS P + P A P PP P PPG P A P A G
Sbjct: 252 PAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGA 311
Query: 482 EPSTAPAPSPPAPKSCLKHRPAAASEGPA-------------ASPPLA--AAESPPVEPG 526
P+ APA PA S + P AA+ PA A+PP A A S P
Sbjct: 312 APAPAPAAGGPAGVSG-QPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370
Query: 527 PGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPG 586
+ P P G P+ A L + S RA P
Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPT 430
Query: 587 VSRPLERASGRLPLARSGPVWRSEAAL---------DDLQGLPEPQHAKPGPRKLAERGP 637
V P RLP P L ++ Q L PQ A + A P
Sbjct: 431 VLAP------RLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQP 484
Query: 638 QDSGDRAASPAGPRKSPQ---EAAAAPGT 663
Q + A PA P +P APGT
Sbjct: 485 QTT--MAPRPATPTSAPPVQISTVQAPGT 511
Score = 68.2 bits (165), Expect = 4e-11
Identities = 91/322 (28%), Positives = 114/322 (35%), Gaps = 35/322 (10%)
Query: 515 LAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKF 574
LAA+ + P + + AAA PAGA A P AE GA GA
Sbjct: 33 LAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAE--GAP--GAAPE 88
Query: 575 SVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAE 634
+ RARP G + S R PL +GP + +G P +A
Sbjct: 89 PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAA 148
Query: 635 RGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPA-AQEPAPSEDRNPFPVK-LRSTSLS 692
GP+ + A PAGP A PG P P P P + P + L ++
Sbjct: 149 -GPEPAPAGPAKPAGPAALAARAGPGPG---PGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204
Query: 693 LKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARP 752
L A+ V V A +L LPK PA GT + G A P
Sbjct: 205 LNSHHAAAPAVSLVNNGPA------ALLPLPK---------PAAPGTVIQTPPFVGAAAP 249
Query: 753 PEPLSSKPPLPRKPLLQSFTLPHQPAPP---------DAGPGEREPRKEPRTAEKRPLRR 803
P P + PP P + P P P AGP P P A +
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309
Query: 804 GAEKSLPPAATGP-GADGQPAP 824
GA + PAA GP G GQP P
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGP 331
Score = 52.0 bits (123), Expect = 3e-06
Identities = 111/451 (24%), Positives = 148/451 (32%), Gaps = 80/451 (17%)
Query: 452 GPPGPAPEPEREAETEPERGAGTEPERIGTE------PSTAPAPSP--------PAPKSC 497
G P A A E GA EP G P PSP PAP +
Sbjct: 65 GSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAA 124
Query: 498 LKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP---PAGAER 554
P S G A P AAA + EP P A+ A P A P P
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAG-PAKPAGPAALAARAGPGPGPGPGPGPG 183
Query: 555 AAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALD 614
P + A G A+ ++S A A+ + L +GP AAL
Sbjct: 184 PGPGKPAGPGAAQTLNGSAALLNSHHA------------AAPAVSLVNNGP-----AAL- 225
Query: 615 DLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGP----RKSPQEAAAAPGTREPCPAA 670
LP P+ A PG + + P +PA P +P AAAP P PA
Sbjct: 226 ----LPLPKPAAPG--TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279
Query: 671 QEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPL 730
P P P + ++G S +A ++ P
Sbjct: 280 LARPPGHPAGP-PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGG--PAGVSGQPGPGAAAA 336
Query: 731 GTAPALRGTRAPSDQGKGKARPPE--------PLSSKPPLPRKPLLQSFTLPHQPAPPDA 782
AP G +A S + +A PP P S+ + P +Q LP A P
Sbjct: 337 APAP---GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQG-ALPSPAAVPPP 392
Query: 783 GPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPP 842
PG P P+ A + S P AT G T+T L QPP
Sbjct: 393 APG--TPTGLPKGAAGAVTQ---SLSRTPTATTSGIRA-------TLTPTVLAPRLPQPP 440
Query: 843 -------NQEDKPGARTLKSEPGKQAKVPER 866
N + PG ++SE G+ +P++
Sbjct: 441 QNPTNIQNFQLPPGMVLVRSENGQLLMIPQQ 471
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 84.7 bits (208), Expect = 4e-16
Identities = 138/579 (23%), Positives = 197/579 (34%), Gaps = 104/579 (17%)
Query: 272 VSPEER---PSSGQQDVAPDRGPEPGPPAPLPPP---------------GGARARRARLQ 313
+SP+ + P + Q P P P PP P PPP G A +
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYS 668
Query: 314 HSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPS---PPEGPPNPGPDGGK 370
+ L + + G +P TP + + +S + PP+ PP PP P P G
Sbjct: 669 TITRLQNASQHSGA-----LFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGS 723
Query: 371 QDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPE-------GDTTPPETDPAATSE 423
+ PA PCAP+ P+ A P P I + TPP P
Sbjct: 724 AMAQLKPA-PCAPS---------LPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPL 773
Query: 424 APSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEP 483
P A P ++P + PP P P P A+ +P A P T P
Sbjct: 774 PPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTP-PVPPAKKQPAFPASYIPPSPPTPP 832
Query: 484 STAPAPSPPAPKS-CLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKA 542
P P+ P +S C K P+ S P+ +A+ PP P P +++++ P P
Sbjct: 833 VPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPP--PTPPAMESQPLKPV-PAN 889
Query: 543 ERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLAR 602
++PPA ++ K+ SS P P P +S P
Sbjct: 890 VAPQSPPA-----------------VKAKPKWQPSSIPV-PSPDFPPPPPESSLVFPPPP 931
Query: 603 SGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAG--PRKSPQEAA-- 658
PV P P A P P K G + S + +SP G P +PQ +
Sbjct: 932 PSPV--------PAPPPPPPPTASPTPDKSGSPGKKTS--KTSSPGGKKPPPTPQRNSSI 981
Query: 659 -AAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLER 717
++ G P P + P+ + F S S S + + K K + V L
Sbjct: 982 KSSSGAEHPEP--KRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPG 1039
Query: 718 SLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQP 777
L ++ C AP L G D PP PP P L P
Sbjct: 1040 VL-----QQGCVSAKAPVLSG--RGKDSVVEFPSPPSDSDFPPPPPETEL---------P 1083
Query: 778 APPDAGPGEREPRKEPRTAEKRP-----LRRGAEKSLPP 811
PP P P+ A P + +K+ PP
Sbjct: 1084 LPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPP 1122
Score = 51.2 bits (121), Expect = 5e-06
Identities = 105/466 (22%), Positives = 149/466 (31%), Gaps = 74/466 (15%)
Query: 136 PPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVS 195
PP P +P + + A +S +P SPP T V V P +
Sbjct: 803 PPTPTPPVPPAKKQPAFPASY---IPPSPP------------TPPVPVPPPTLPKQQSFC 847
Query: 196 ARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDL 255
A+ + L+PV S + A++ P S ++ + + +S +
Sbjct: 848 AKPPPSPLSPVP---------SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAV 898
Query: 256 TCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPP-------------- 301
P+ + + P P S P P P PP P PP
Sbjct: 899 KAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGK 958
Query: 302 -------PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEP 354
PGG + ++SS ++S E P + PS + P + + E
Sbjct: 959 KTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEP-KRPSVDSLVSKFTPPAESGSPSKET 1017
Query: 355 PSPPEGPPNPGP--------DGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAI 406
PP PP PG G Q G P K V S FP
Sbjct: 1018 LPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP--- 1074
Query: 407 PEGDTTPPETD-PAATSEAPSARDGPERSVPKEAEPTPPVLPDE-EKGPPGPAPEPEREA 464
PPET+ P E P+ G + PK A P P + K AP P R
Sbjct: 1075 ----PPPPETELPLPPIEIPAVFSG--NTSPKVAVVNPQ--PQQWSKMSVKKAPPPTRPK 1126
Query: 465 ETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVE 524
+ R E T + P P +PKS L +P G A
Sbjct: 1127 RNDSTRLTQAEISEQPTMATVVP-QVPTSPKSSLSVQP-----GFLADLNRTLQRKSITR 1180
Query: 525 PGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG 570
G S A P + A PP E + ++KA GG+ + G
Sbjct: 1181 HGSLSSRMSRAEPTATMDDMA-LPPPPPELLSDQQKAGYGGSHISG 1225
Score = 49.3 bits (116), Expect = 2e-05
Identities = 94/444 (21%), Positives = 133/444 (29%), Gaps = 78/444 (17%)
Query: 396 EDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPG 455
E + P+ + +P P P S+ P +P P PP PP
Sbjct: 596 ESMNRPYTSLVPPLSPQPKIVTPYTASQ-------PSPPLPPPPPPPPP------PPPPP 642
Query: 456 PAPEPEREAETEPERGAGTEP-------ERIGTEPSTAPA----PSPPAPKS-CLKHRPA 503
P P P +++ P G+ R+ + A P+PP +S +K +
Sbjct: 643 PPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQIL 702
Query: 504 AASEGPAASPPLAAAESPPVEPGPGSLDAEAA-APERPKAERAEAPPAGAERAAPERKAE 562
G PP PP P PGS A+ AP P + APP + + +
Sbjct: 703 VPPNGVVPPPP-----PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQ 757
Query: 563 RGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEP 622
V+ P P + PL Q P+P
Sbjct: 758 -------------VAPPTPPPPPPIPAPLPP-----------------------QAPPKP 781
Query: 623 QHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPF 682
P P P + +P P ++ A P + P P P P
Sbjct: 782 LVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPV----PP 837
Query: 683 PVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAP 742
P + S K V V + A P E PL PA ++P
Sbjct: 838 PTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTP--PAMESQPLKPVPANVAPQSP 895
Query: 743 -SDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPL 801
+ + K K +P P P P S P PP P P P TA P
Sbjct: 896 PAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFP----PPPPSPVPAPPPPPPPTASPTPD 951
Query: 802 RRGAEKSLPPAATGPGADGQPAPP 825
+ G+ + PG P P
Sbjct: 952 KSGSPGKKTSKTSSPGGKKPPPTP 975
Score = 33.9 bits (76), Expect = 0.75
Identities = 81/380 (21%), Positives = 126/380 (33%), Gaps = 52/380 (13%)
Query: 134 MGPPPPPGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDST 193
+ P PP + + + + P PPE SL+ P + + P + T
Sbjct: 890 VAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPT 949
Query: 194 VSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLS-------SR 246
D S P + +S + K + P QR+S ++ S R
Sbjct: 950 -----PDKS-------GSPGKKTSKTSSPGGK---KPPPTPQRNSSIKSSSGAEHPEPKR 994
Query: 247 AQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGAR 306
+SL P E + K L P P G+ +++ G P G
Sbjct: 995 PSVDSLVSKFTPPAESGSPSKETLP-PPAAPPKPGKLNLS-------GVNLPGVLQQGCV 1046
Query: 307 ARRARLQHSSALTASVEEGGVPGED--PSSRPATPELAEPESAPTLRVEPPSPPEGPPNP 364
+ +A + + VE P + P P T P P + SP NP
Sbjct: 1047 SAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNP 1106
Query: 365 GPDGGKQDG--EAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPET------ 416
P + +APP P P + + + A T +P+ T+P +
Sbjct: 1107 QPQQWSKMSVKKAPP--PTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPG 1164
Query: 417 ---DPAATSEAPS-ARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGA 472
D T + S R G S AEPT + D+ PP P PE ++ +
Sbjct: 1165 FLADLNRTLQRKSITRHGSLSSRMSRAEPTATM--DDMALPP---PPPELLSDQQKAGYG 1219
Query: 473 GTEPERIGTEPSTAPAPSPP 492
G+ T P P+PP
Sbjct: 1220 GSHISGYAT-LRRGPPPAPP 1238
>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 84.3 bits (207), Expect = 5e-16
Identities = 164/686 (23%), Positives = 230/686 (33%), Gaps = 162/686 (23%)
Query: 277 RPSSGQQDVA---PDRGPEPGPPAPLP-PPGGARARRARLQHSSALTASVEEGGVPGEDP 332
RP QD+ P GP PGPP + PPGG
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG---------------------------- 160
Query: 333 SSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV 392
S P+ P A P P L +EPP PP P P P + +PP +P+ +
Sbjct: 161 SPLPSPPSTAPPP--PPLLLEPPPPPSMAPPPPP---VLEALSPPHTLSSPS-------I 208
Query: 393 CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVP--------------KE 438
P D P P PP PA + A G P ++
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268
Query: 439 AEPT---PPVLPDEEKGPP-GPAPEPE----------------------REAETEPERGA 472
AE T PP P E KG GP PEP +EA+ P +
Sbjct: 269 AEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 473 GT---EPERIGTEPS------------TAPAPSPP------APKSCLKHRPAAASEGPAA 511
G P R+ PS AP P P AP S + + ++ A
Sbjct: 329 GATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388
Query: 512 SPPLAAAESPPVEP-GPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG 570
+PP A PP P P + AAP P A++A PPAG +
Sbjct: 389 TPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS------------ 436
Query: 571 AKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPV-WRSEAALDDLQGLPEPQ--HAKP 627
SS +P+P P AS S PV WR + ++ L+ ++
Sbjct: 437 ------SSPALKPKPNPPSPENTAS-------SAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 628 GPRKLAER-GPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPA---PSEDRNPFP 683
R L+ R GP + GPR +E + ++ P E + S
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPS 743
L S+ +D + V+ + R E RL + K L P L G R
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI-C 601
Query: 744 DQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQ----PA-PPDAGPGEREPRKE---PRT 795
+ G + +P++ P LL + +L + PA PP A P P K P T
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
Query: 796 AEK------RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPG 849
K PL+ + + P AT A A T T Q P Q +KP
Sbjct: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
Query: 850 ARTL--------KSEPGKQAKVPERG 867
++ + + P + ++P +G
Sbjct: 722 SQEVSTPSQARGEGSPSEATRLPTQG 747
Score = 66.6 bits (161), Expect = 1e-10
Identities = 157/690 (22%), Positives = 220/690 (31%), Gaps = 119/690 (17%)
Query: 134 MGPPPPP---GGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVS 190
M PPPPP P + + D +P +PP L + P + P S
Sbjct: 186 MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPP----LAFLAPPPPPVPAPAPPAPAS 241
Query: 191 DSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSE 250
TV R+ P + +S L+ A+ PR+ K L +
Sbjct: 242 PHTVGTRL----FPPGGVTKW--KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295
Query: 251 SL---SDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARA 307
S P P+ E R G AP R PLPP R
Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR-------LPLPPSFHIRP 348
Query: 308 RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES-----APTLRVEPPSPPEGPP 362
S E PGE ++ PA+P L + +S A T PP PP PP
Sbjct: 349 A------SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP 402
Query: 363 NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP--EGDTTPPETDPAA 420
P P APP P AP A++ P ++ P + PP + A
Sbjct: 403 LPPP--------APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
Query: 421 TSEAPSARDGPERSVPKEA-----------------EPTPPVLPDEEKGPPGPAPEPERE 463
+S RD + + P P V P ++G GP PE+E
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR-LPEKE 513
Query: 464 A-------ETEPERGAGTEPERIG----TEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
+T P G + +G TE AP+ + P + P S
Sbjct: 514 TLLSLPAKDTPP----GVPEKSLGGSSLTETEAAPSLTLP-----------SVDYIPQDS 558
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAK 572
P +P V L+A ++ AE+ P G+ P+ + E G GA
Sbjct: 559 P------TPSVRQIRNELEARLSS----AAEKEAKPSIGS--LPPKPRLEGGRICENGAD 606
Query: 573 KFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKL 632
+S A+ P S L + P A GP +A + +P P
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE--PAIPPKATLWPATPPK 664
Query: 633 AERGPQDSGDRAASPAGPRKSPQ-EAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
A GP + P P K+ A A+ T P +Q A +D P + S
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMA-EKDSGPAGQPEKPASQ 723
Query: 692 SLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA---------- 741
+ A E + + RS P + G P L
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 742 ---PSDQGKGKARPPEPLSSKPP--LPRKP 766
P+ G A P EP+ K P LP KP
Sbjct: 784 VVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813
>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
sapiens]
Length = 1188
Score = 84.3 bits (207), Expect = 5e-16
Identities = 164/686 (23%), Positives = 230/686 (33%), Gaps = 162/686 (23%)
Query: 277 RPSSGQQDVA---PDRGPEPGPPAPLP-PPGGARARRARLQHSSALTASVEEGGVPGEDP 332
RP QD+ P GP PGPP + PPGG
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG---------------------------- 160
Query: 333 SSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV 392
S P+ P A P P L +EPP PP P P P + +PP +P+ +
Sbjct: 161 SPLPSPPSTAPPP--PPLLLEPPPPPSMAPPPPP---VLEALSPPHTLSSPS-------I 208
Query: 393 CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVP--------------KE 438
P D P P PP PA + A G P ++
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268
Query: 439 AEPT---PPVLPDEEKGPP-GPAPEPE----------------------REAETEPERGA 472
AE T PP P E KG GP PEP +EA+ P +
Sbjct: 269 AEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 473 GT---EPERIGTEPS------------TAPAPSPP------APKSCLKHRPAAASEGPAA 511
G P R+ PS AP P P AP S + + ++ A
Sbjct: 329 GATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388
Query: 512 SPPLAAAESPPVEP-GPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG 570
+PP A PP P P + AAP P A++A PPAG +
Sbjct: 389 TPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS------------ 436
Query: 571 AKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPV-WRSEAALDDLQGLPEPQ--HAKP 627
SS +P+P P AS S PV WR + ++ L+ ++
Sbjct: 437 ------SSPALKPKPNPPSPENTAS-------SAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 628 GPRKLAER-GPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPA---PSEDRNPFP 683
R L+ R GP + GPR +E + ++ P E + S
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPS 743
L S+ +D + V+ + R E RL + K L P L G R
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI-C 601
Query: 744 DQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQ----PA-PPDAGPGEREPRKE---PRT 795
+ G + +P++ P LL + +L + PA PP A P P K P T
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
Query: 796 AEK------RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPG 849
K PL+ + + P AT A A T T Q P Q +KP
Sbjct: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
Query: 850 ARTL--------KSEPGKQAKVPERG 867
++ + + P + ++P +G
Sbjct: 722 SQEVSTPSQARGEGSPSEATRLPTQG 747
Score = 66.6 bits (161), Expect = 1e-10
Identities = 157/690 (22%), Positives = 220/690 (31%), Gaps = 119/690 (17%)
Query: 134 MGPPPPP---GGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVS 190
M PPPPP P + + D +P +PP L + P + P S
Sbjct: 186 MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPP----LAFLAPPPPPVPAPAPPAPAS 241
Query: 191 DSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSE 250
TV R+ P + +S L+ A+ PR+ K L +
Sbjct: 242 PHTVGTRL----FPPGGVTKW--KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295
Query: 251 SL---SDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARA 307
S P P+ E R G AP R PLPP R
Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR-------LPLPPSFHIRP 348
Query: 308 RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES-----APTLRVEPPSPPEGPP 362
S E PGE ++ PA+P L + +S A T PP PP PP
Sbjct: 349 A------SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP 402
Query: 363 NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP--EGDTTPPETDPAA 420
P P APP P AP A++ P ++ P + PP + A
Sbjct: 403 LPPP--------APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
Query: 421 TSEAPSARDGPERSVPKEA-----------------EPTPPVLPDEEKGPPGPAPEPERE 463
+S RD + + P P V P ++G GP PE+E
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR-LPEKE 513
Query: 464 A-------ETEPERGAGTEPERIG----TEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
+T P G + +G TE AP+ + P + P S
Sbjct: 514 TLLSLPAKDTPP----GVPEKSLGGSSLTETEAAPSLTLP-----------SVDYIPQDS 558
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAK 572
P +P V L+A ++ AE+ P G+ P+ + E G GA
Sbjct: 559 P------TPSVRQIRNELEARLSS----AAEKEAKPSIGS--LPPKPRLEGGRICENGAD 606
Query: 573 KFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKL 632
+S A+ P S L + P A GP +A + +P P
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE--PAIPPKATLWPATPPK 664
Query: 633 AERGPQDSGDRAASPAGPRKSPQ-EAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
A GP + P P K+ A A+ T P +Q A +D P + S
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMA-EKDSGPAGQPEKPASQ 723
Query: 692 SLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA---------- 741
+ A E + + RS P + G P L
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 742 ---PSDQGKGKARPPEPLSSKPP--LPRKP 766
P+ G A P EP+ K P LP KP
Sbjct: 784 VVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 84.3 bits (207), Expect = 5e-16
Identities = 116/450 (25%), Positives = 145/450 (32%), Gaps = 58/450 (12%)
Query: 274 PEERPSSGQQDVAPDRGPEPGPPAPL-PPPGGARARRARLQHSSALT--ASVEEGGVPGE 330
P E P + EP P A P GG R A SS+ T +S G
Sbjct: 192 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251
Query: 331 DPSSRPATPELAEPESAPTLR---VEPP-------------SP-----PEGPPNPGPDGG 369
PA P +P+ LR V PP SP P PP+P
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPS 311
Query: 370 KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARD 429
Q +PPA P + AT P P P T PP+ PA A
Sbjct: 312 LQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLA-TPPPQAPPALALPPLQAPP 370
Query: 430 GPERSVPKEAEPTP-PVLPDEE-----KGPPGPAPEPEREAETEPERGAGTEPERIGTEP 483
P S P TP P P+ + P P P P +A P P T P
Sbjct: 371 SPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS--ATPP 428
Query: 484 STAPA----------PSPPA-PKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDA 532
S AP PSPPA P P + P A+PPL A+ PP P +
Sbjct: 429 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPP 488
Query: 533 EAAAPERPKAERAEAP--PAGAERAAPERKAERGGAELRGAKKFSV----------SSCR 580
A P P + +AP P+ + +P + A V + R
Sbjct: 489 LQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPR 548
Query: 581 ARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDS 640
P PG + L LA P S + L G H+ E DS
Sbjct: 549 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 608
Query: 641 GDRAASPAGPRKSPQEAAAAPG--TREPCP 668
G + A P + AA P +R P P
Sbjct: 609 GPEGGAAASPPPDAELAACHPAAWSRGPAP 638
Score = 80.5 bits (197), Expect = 7e-15
Identities = 135/565 (23%), Positives = 186/565 (32%), Gaps = 85/565 (15%)
Query: 287 PDRGPEPGPPAPLPPPGGARARRARLQHSSA---LTASVEEGGVPGEDPSSRPATPELAE 343
P+ P GP PP R RA +++ +++ G P + AE
Sbjct: 71 PESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 130
Query: 344 PESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFP 403
A E P + G ++D P G +PA + + P P
Sbjct: 131 ETVARGKATEAPK-----RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAP 185
Query: 404 TAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPERE 463
+A P T P ++ SE + E P P G PA
Sbjct: 186 SARPRPPTEGPRKSVSSASEHSTT----------EPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 464 AETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRP---------AAASEGPAASPP 514
+ T A + P GT P PS P PK RP AA + GP +S P
Sbjct: 236 SATPLSSPARSGPSARGT-PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 515 LA--AAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAEL---- 568
LA + +PP P SL + P P ++ + + +A + L
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP 354
Query: 569 -RGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKP 627
+ ++ +A P P S PL PLA P + A+ LQ P P
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLS------PLATPSPQAPNALAVHLLQA---PFSPPP 405
Query: 628 GPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEP-APSEDRNP-FPVK 685
P A P S + S P ++P AA P P P A P +PS P P
Sbjct: 406 SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 465
Query: 686 LRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQ 745
L + L L P + P P L+ +P
Sbjct: 466 LAAPPLQL---------------------------AKPPPQAPPALATPPLQALPSPPAS 498
Query: 746 GKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRT----AEKRPL 801
G+A P S LP PL T P Q P A P + P P + A +RP
Sbjct: 499 FPGQA----PFSPSASLPMSPLA---TPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPP 551
Query: 802 RRGAEKSLP-PAATGPGADGQPAPP 825
G + S+ P T A G P PP
Sbjct: 552 TPGPDTSVSGPRLTLALAPGPPPPP 576
Score = 76.3 bits (186), Expect = 1e-13
Identities = 124/485 (25%), Positives = 160/485 (32%), Gaps = 76/485 (15%)
Query: 140 PGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARIS 199
P PA+ G A G PR+P S G ++ V+P + +S
Sbjct: 239 PLSSPARSGPSAR------GTPRAPAHPSQPKPKGL-QALRPPQVTPPRKDAAPALGPLS 291
Query: 200 DNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTP 259
+ LA + + P+ S+ + L P S L S + S L P
Sbjct: 292 SSPLATPSPSAPPSPSAP-----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 260 EEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPP-APL--PPPGGARARRARLQHSS 316
PL P+ P+ + P PP +PL P P A L +
Sbjct: 347 LS------PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAP 400
Query: 317 ALTASVEEGGVPGEDPSSRPATPELAEPE------SAPTLRVEPPSPPEGPP-----NPG 365
P P+S P +P P +AP L+V PPSPP PP P
Sbjct: 401 FSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQV-PPSPPASPPMSPSATPP 459
Query: 366 PDGGK-------QDGEAPPAGPCAPATDKAEEVVCAPEDVASPFP----TAIPEGD--TT 412
P Q + PP P A AT + + P P ++P T
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATP 519
Query: 413 PPETDPAATSEAPSARDGPERSVPKEAEPTPPVL-PDEE-KGP-------PGPAPEPERE 463
PP+ P + P S +A PP PD GP PGP P P R
Sbjct: 520 PPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 464 AETE--------PERGAGTEPERI---GTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
+ A + PE + + P A SPP PAA S GPA
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA-- 637
Query: 513 PPLAAAESP------PVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGA 566
PPLA +P P GPGS D E E A P GA P GG
Sbjct: 638 PPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESA-TPAPGALDPGPS-PGTSGGK 695
Query: 567 ELRGA 571
GA
Sbjct: 696 AAAGA 700
Score = 73.6 bits (179), Expect = 9e-13
Identities = 142/581 (24%), Positives = 193/581 (33%), Gaps = 106/581 (18%)
Query: 350 LRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEG 409
L PP P PP P + G A G P ++A + A IPE
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGR-KPLAERAGGIGGA----------TIPE- 72
Query: 410 DTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPER------- 462
+ P P TS P++ G E PP + PGP P R
Sbjct: 73 --SAPRAGPTRTSRPPASGRG---------ERAPPA----KNTSPGPVSSPGRASGTTRP 117
Query: 463 ----------EAETEPERGAGTE-PERI-----GTEPSTAPAPSPPAPKSCLKHRPAAAS 506
AE RG TE P+R ++ P P P+P + R AA +
Sbjct: 118 GPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR-AAGT 176
Query: 507 EGPAASPPLAAAESPPVEPGP----------GSLDAEAAAPERPKAERAEAPPAG---AE 553
E P +A PP E GP + + AA RP A PA +
Sbjct: 177 EVGLPRPAPSARPRPPTE-GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 554 RAAPERKAERGGAELRGAKKFSVSSCRARPR-------PGVSRPLERASGRL------PL 600
A P R G RG + + +P+ P V+ P + A+ L PL
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 295
Query: 601 ARSGP-VWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPA--------GPR 651
A P S +A LQ LP P P + P + P+ P
Sbjct: 296 ATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPP 355
Query: 652 KSPQEAAAAPGTREPCPAAQEP-APSEDRNP-FPVKLRSTSLSLKYRDGASQEVKGVKRY 709
++P A P P P A P +P +P P L L + S V+
Sbjct: 356 QAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 415
Query: 710 SAEVRLERSLTVLPKEEKCPLGTAPALRGTRAP------SDQGKGKARPPEPLS------ 757
A + S T P + P AP L+ +P S + P PL+
Sbjct: 416 PASPPVSPSAT--PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 758 SKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPG 817
+KPP P L + L P+PP + PG+ P + PL ++ PP P
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQ-APFSPSASLPMSPLATPPPQA-PPVLAAPL 531
Query: 818 ADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPG 858
P+PP + RR P P TL PG
Sbjct: 532 LQVPPSPPASPTLQAPRRPPTPGPDTSVSGP-RLTLALAPG 571
Score = 54.7 bits (130), Expect = 4e-07
Identities = 107/407 (26%), Positives = 141/407 (34%), Gaps = 69/407 (16%)
Query: 499 KHRPAAASEGPAASPPLAAAESPPVEPGPGS---------LDAEAAAPERPKAERA---- 545
K + AA+ PAA P PP P P L A A +P AERA
Sbjct: 7 KAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG 66
Query: 546 -EAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSG 604
P A RA P R R A RG + + P VS P RASG R G
Sbjct: 67 GATIPESAPRAGPTR-TSRPPASGRGERAPPAKNTSPGP---VSSP-GRASG---TTRPG 118
Query: 605 PVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTR 664
P+ + + + + + A P++ A +P P + + A GT
Sbjct: 119 PLGQKGLRISAEETVARGK-ATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTE 177
Query: 665 EPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLE----RSLT 720
P PAPS P R + S +R SA L+ RSL+
Sbjct: 178 VGLP---RPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLS 234
Query: 721 VLPKEEKCPLGTAPALRGT-RAPSDQGKGK------ARPPE-------------PLSSKP 760
P + P+ RGT RAP+ + K RPP+ PLSS P
Sbjct: 235 SSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 294
Query: 761 ---PLPRKPLLQSF--TLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATG 815
P P P S +L P+PP P + T+ P + LP
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPP------ATPPSQATTSLGSPTLQATHSFLPSPPLS 348
Query: 816 PGADGQP-APPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQA 861
P A P APP + + L PP+ P L + P QA
Sbjct: 349 PLATPPPQAPPALALP------PLQAPPSPPASPPLSPL-ATPSPQA 388
Score = 32.0 bits (71), Expect = 2.9
Identities = 34/110 (30%), Positives = 40/110 (36%), Gaps = 16/110 (14%)
Query: 724 KEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKP-----LLQSFTLPHQPA 778
K +K G A RAP G P P S +PP P P L + + +P
Sbjct: 4 KRDKAKAGAAARTPAARAP-----GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPL 58
Query: 779 PPDAG--PGEREPRKEPR---TAEKRPLRRGAEKSLPPAA-TGPGADGQP 822
AG G P PR T RP G + PPA T PG P
Sbjct: 59 AERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSP 108
>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
sapiens]
Length = 1188
Score = 84.3 bits (207), Expect = 5e-16
Identities = 164/686 (23%), Positives = 230/686 (33%), Gaps = 162/686 (23%)
Query: 277 RPSSGQQDVA---PDRGPEPGPPAPLP-PPGGARARRARLQHSSALTASVEEGGVPGEDP 332
RP QD+ P GP PGPP + PPGG
Sbjct: 129 RPGQYGQDLLIPPPPPGPAPGPPQDISEPPGG---------------------------- 160
Query: 333 SSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV 392
S P+ P A P P L +EPP PP P P P + +PP +P+ +
Sbjct: 161 SPLPSPPSTAPPP--PPLLLEPPPPPSMAPPPPP---VLEALSPPHTLSSPS-------I 208
Query: 393 CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVP--------------KE 438
P D P P PP PA + A G P ++
Sbjct: 209 PTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTRLFPPGGVTKWKSDVALNGRQ 268
Query: 439 AEPT---PPVLPDEEKGPP-GPAPEPE----------------------REAETEPERGA 472
AE T PP P E KG GP PEP +EA+ P +
Sbjct: 269 AEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEE 328
Query: 473 GT---EPERIGTEPS------------TAPAPSPP------APKSCLKHRPAAASEGPAA 511
G P R+ PS AP P P AP S + + ++ A
Sbjct: 329 GATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAG 388
Query: 512 SPPLAAAESPPVEP-GPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG 570
+PP A PP P P + AAP P A++A PPAG +
Sbjct: 389 TPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKS------------ 436
Query: 571 AKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPV-WRSEAALDDLQGLPEPQ--HAKP 627
SS +P+P P AS S PV WR + ++ L+ ++
Sbjct: 437 ------SSPALKPKPNPPSPENTAS-------SAPVDWRDPSQMEKLRNELAAYLCGSRR 483
Query: 628 GPRKLAER-GPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPA---PSEDRNPFP 683
R L+ R GP + GPR +E + ++ P E + S
Sbjct: 484 EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPS 743
L S+ +D + V+ + R E RL + K L P L G R
Sbjct: 544 PSLTLPSVDYIPQDSPTPSVRQI-RNELEARLSSAAEKEAKPSIGSLPPKPRLEGGRI-C 601
Query: 744 DQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQ----PA-PPDAGPGEREPRKE---PRT 795
+ G + +P++ P LL + +L + PA PP A P P K P T
Sbjct: 602 ENGADDDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIPPKATLWPAT 661
Query: 796 AEK------RPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPG 849
K PL+ + + P AT A A T T Q P Q +KP
Sbjct: 662 PPKATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAGQPEKPA 721
Query: 850 ARTL--------KSEPGKQAKVPERG 867
++ + + P + ++P +G
Sbjct: 722 SQEVSTPSQARGEGSPSEATRLPTQG 747
Score = 66.6 bits (161), Expect = 1e-10
Identities = 157/690 (22%), Positives = 220/690 (31%), Gaps = 119/690 (17%)
Query: 134 MGPPPPP---GGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVS 190
M PPPPP P + + D +P +PP L + P + P S
Sbjct: 186 MAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPP----LAFLAPPPPPVPAPAPPAPAS 241
Query: 191 DSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSE 250
TV R+ P + +S L+ A+ PR+ K L +
Sbjct: 242 PHTVGTRL----FPPGGVTKW--KSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPH 295
Query: 251 SL---SDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARA 307
S P P+ E R G AP R PLPP R
Sbjct: 296 LTFPRSFKVPPPTPVRTSSIPVQEAQEAPRKEEGATKKAPSR-------LPLPPSFHIRP 348
Query: 308 RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPES-----APTLRVEPPSPPEGPP 362
S E PGE ++ PA+P L + +S A T PP PP PP
Sbjct: 349 A------SQVYPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPP 402
Query: 363 NPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP--EGDTTPPETDPAA 420
P P APP P AP A++ P ++ P + PP + A
Sbjct: 403 LPPP--------APPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPALKPKPNPPSPENTA 454
Query: 421 TSEAPSARDGPERSVPKEA-----------------EPTPPVLPDEEKGPPGPAPEPERE 463
+S RD + + P P V P ++G GP PE+E
Sbjct: 455 SSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPR-LPEKE 513
Query: 464 A-------ETEPERGAGTEPERIG----TEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
+T P G + +G TE AP+ + P + P S
Sbjct: 514 TLLSLPAKDTPP----GVPEKSLGGSSLTETEAAPSLTLP-----------SVDYIPQDS 558
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAK 572
P +P V L+A ++ AE+ P G+ P+ + E G GA
Sbjct: 559 P------TPSVRQIRNELEARLSS----AAEKEAKPSIGS--LPPKPRLEGGRICENGAD 606
Query: 573 KFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKL 632
+S A+ P S L + P A GP +A + +P P
Sbjct: 607 DDKLSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPE--PAIPPKATLWPATPPK 664
Query: 633 AERGPQDSGDRAASPAGPRKSPQ-EAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSL 691
A GP + P P K+ A A+ T P +Q A +D P + S
Sbjct: 665 ATLGPATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMA-EKDSGPAGQPEKPASQ 723
Query: 692 SLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA---------- 741
+ A E + + RS P + G P L
Sbjct: 724 EVSTPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSREVA 783
Query: 742 ---PSDQGKGKARPPEPLSSKPP--LPRKP 766
P+ G A P EP+ K P LP KP
Sbjct: 784 VVMPTLARGGAAGPGEPVEVKEPPGLPAKP 813
>gi|41349482 proline-rich protein BstNI subfamily 1 isoform 1
preproprotein [Homo sapiens]
Length = 331
Score = 83.6 bits (205), Expect = 8e-16
Identities = 83/322 (25%), Positives = 116/322 (36%), Gaps = 40/322 (12%)
Query: 251 SLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRA 310
+LS E+ EE P L + PS + P PG P PP GG + +
Sbjct: 12 ALSSAQNLNEDVSQEESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQ-- 69
Query: 311 RLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVE----PPSPPEGPPNPGP 366
+G P D S P +P +P+ P PP PP P P P
Sbjct: 70 -----GPPPPGKPQGPPPQGDKSRSPRSPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPP 123
Query: 367 DGGKQ-DGEAPPAGPCAPAT--DKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSE 423
GG + G PP P P DK+ +P P P+G P
Sbjct: 124 QGGNRPQGPPPPGKPQGPPPQGDKSR----SPRS-----PPGKPQGPPPQGGNQPQGPPP 174
Query: 424 APSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEP 483
P GP K+ + PP P + +GPP P + R +++ P + G P+ G +P
Sbjct: 175 PPGKPQGPPPQGGKKPQGPPP--PGKPQGPP-PQGDKSRSSQSPPGKPQGPPPQG-GNQP 230
Query: 484 STAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEA--AAPERPK 541
P P P P+ P P PP + PP + G S A + P+ P
Sbjct: 231 Q-GPPPPPGKPQG----PPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPP 285
Query: 542 AE-----RAEAPPAGAERAAPE 558
+ + PPAG P+
Sbjct: 286 QQEGNNPQGPPPPAGGNPQQPQ 307
Score = 75.5 bits (184), Expect = 2e-13
Identities = 66/250 (26%), Positives = 88/250 (35%), Gaps = 26/250 (10%)
Query: 278 PSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPA 337
P G Q P P PG P PP GG R + +G P D S P
Sbjct: 102 PQGGNQPQGPP--PPPGKPQGPPPQGGNRPQ-------GPPPPGKPQGPPPQGDKSRSPR 152
Query: 338 TPELAEPESAPTLRVE----PPSPPEGPPNPGPDGGKQ-DGEAPPAGPCAPATDKAEEVV 392
+P +P+ P PP PP P P P GGK+ G PP P P
Sbjct: 153 SPP-GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQ------ 205
Query: 393 CAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKG 452
+ +S P P+G P P GP + + PP P + +G
Sbjct: 206 -GDKSRSSQSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPP--PGKPQG 262
Query: 453 PPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
PP + A + P + G P++ G P P P+ P+ + PA +GP
Sbjct: 263 PPAQGGSKSQSARSPPGKPQG-PPQQEGNNPQGPPPPAGGNPQQ-PQAPPAGQPQGPPRP 320
Query: 513 PPLAAAESPP 522
P PP
Sbjct: 321 PQGGRPSRPP 330
Score = 67.4 bits (163), Expect = 6e-11
Identities = 77/335 (22%), Positives = 106/335 (31%), Gaps = 48/335 (14%)
Query: 330 EDPSSRPATPELAEPESAPTLRVEPPSP--PEGPPNPGPDGGKQDGEAPPAGPCAPAT-- 385
E PS P+ P+ + PP P P+GPP G G K G PP P P
Sbjct: 27 ESPSLIAGNPQGPSPQGGNKPQGPPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQG 84
Query: 386 DKAEEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDG--PERSVPKEAEPTP 443
DK+ P P P + PP P + P + G P+ P P
Sbjct: 85 DKSRSPRSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGNRPQGPPPPGKPQGP 141
Query: 444 PVLPDEEKGP---PGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKH 500
P D+ + P PG P + +P+ + G P P P P +
Sbjct: 142 PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQG 201
Query: 501 RPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERK 560
P + ++ P + PP + G + P P + P G + P
Sbjct: 202 PPPQGDKSRSSQSPPGKPQGPPPQGG----NQPQGPPPPPGKPQGPPPQGGNKPQGPPPP 257
Query: 561 AERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLP 620
+ G +G K S AR PG + + G P QG P
Sbjct: 258 GKPQGPPAQGGSK----SQSARSPPGKPQGPPQQEGNNP-----------------QGPP 296
Query: 621 EPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQ 655
P P Q A P GP + PQ
Sbjct: 297 PPAGGNP---------QQPQAPPAGQPQGPPRPPQ 322
Score = 55.5 bits (132), Expect = 2e-07
Identities = 74/337 (21%), Positives = 106/337 (31%), Gaps = 51/337 (15%)
Query: 489 PSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP 548
P P+P+ K + G PP P P PG + P+ K+ +P
Sbjct: 36 PQGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--PQGPPPQGDKSRSPRSP 93
Query: 549 PAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWR 608
P + P+ GG + +G P PG + G P
Sbjct: 94 PGKPQGPPPQ-----GGNQPQGPP----------PPPGKPQGPPPQGGNRP--------- 129
Query: 609 SEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCP 668
QG P P KP +GP GD++ SP P PQ G + P
Sbjct: 130 --------QGPPPP--GKP-------QGPPPQGDKSRSPRSPPGKPQGPPPQGGNQ---P 169
Query: 669 AAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKC 728
P P + + P P + +G K S++ + P+
Sbjct: 170 QGPPPPPGKPQGPPPQGGKKPQGPPPPGKPQGPPPQGDKSRSSQSPPGKPQGPPPQGGNQ 229
Query: 729 PLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGERE 788
P G P + P QG K + P P P P+ P Q + P P +
Sbjct: 230 PQGPPPPPGKPQGPPPQGGNKPQGPPP----PGKPQGPPAQGGSKSQSARSPPGKP-QGP 284
Query: 789 PRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPP 825
P++E + P G P A G P PP
Sbjct: 285 PQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPP 321
Score = 46.6 bits (109), Expect = 1e-04
Identities = 44/138 (31%), Positives = 55/138 (39%), Gaps = 12/138 (8%)
Query: 740 RAPSDQGKGKARPPEPLSSKPPLP-----RKPLLQSFTLPHQP-APPDAGPGEREPRKEP 793
+ PS QG K + P P KP P KP Q P +P PP G R PR P
Sbjct: 37 QGPSPQGGNKPQGPPPPPGKPQGPPPQGGNKP--QGPPPPGKPQGPPPQGDKSRSPRSPP 94
Query: 794 RTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTL 853
+ P + G + PP G G P G PP Q DK +R+
Sbjct: 95 GKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQGGNRPQGPPPPGKPQGPPPQGDK--SRSP 151
Query: 854 KSEPGK-QAKVPERGQEP 870
+S PGK Q P+ G +P
Sbjct: 152 RSPPGKPQGPPPQGGNQP 169
Score = 45.4 bits (106), Expect = 2e-04
Identities = 50/166 (30%), Positives = 64/166 (38%), Gaps = 36/166 (21%)
Query: 729 PLGTAPALRGTRAP-SDQGKGKARPPE----PLSSKPP--LPRKPLLQSFTLPHQP---- 777
P G P +R+P S GK + PP+ P PP P+ P Q P P
Sbjct: 77 PQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNRPQGPPPPG 136
Query: 778 ---APPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATG-----PGADGQ----PAPP 825
PP G R PR P + P + G + PP G P G+ P PP
Sbjct: 137 KPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGKKPQGPPPP 196
Query: 826 WITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGK-QAKVPERGQEP 870
G PP Q DK +R+ +S PGK Q P+ G +P
Sbjct: 197 ----------GKPQGPPPQGDK--SRSSQSPPGKPQGPPPQGGNQP 230
Score = 33.5 bits (75), Expect = 0.98
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 2/47 (4%)
Query: 131 NVKMGPPPP--PGGLPAKRGEDAGMSSEDDGLPRSPPEMSLLHDVGP 175
N GPPPP P G PA+ G + + G P+ PP+ + GP
Sbjct: 249 NKPQGPPPPGKPQGPPAQGGSKSQSARSPPGKPQGPPQQEGNNPQGP 295
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 82.8 bits (203), Expect = 1e-15
Identities = 176/760 (23%), Positives = 252/760 (33%), Gaps = 155/760 (20%)
Query: 205 PVADFSYPAESSSCLDNSAAKHKLQVK-----------PRNQRSSKMRRLSSRAQSESLS 253
P +S ESSS + + K + K PR +R ++ R++SES
Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226
Query: 254 DLTCTP------EEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARA 307
+P + ++ + K +P + + + D A+
Sbjct: 227 RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKT 286
Query: 308 RRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGP------ 361
L S AS G G+ P S P T P S T +P SP E
Sbjct: 287 HTTALAGRSPSPASGRRG--EGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKE 344
Query: 362 -----PNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPET 416
P+P P+ E P P + A SP P A TTP
Sbjct: 345 KSATRPSPSPERSSTGPEPPAPTP-----------LLAERHGGSPQPLA-----TTPLSQ 388
Query: 417 DPA-ATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEPERGAGTE 475
+P SEA RD RS PK E P E PP P P T+ R A +
Sbjct: 389 EPVNPPSEASPTRD---RSPPKSPEKLPQ-SSSSESSPPSPQP-------TKVSRHASSS 437
Query: 476 PERIGTEPSTAPAP-------SPPAPKS----------CLKHRPA---AASEGPAASPPL 515
PE P APAP S P K+ H P+ S PA +
Sbjct: 438 PE----SPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRG 493
Query: 516 AAAESPPVEPGPG---------SLDAE----AAAPERPKAERAEAPPA-----GAERAAP 557
+ P + G S A+ + +P+R R+ P +R
Sbjct: 494 RSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGR 553
Query: 558 ERKAERGGAELRGAKKFSVSSCRARPRPGVSR---PLERAS-GRLPLARSGPVWRSEAAL 613
R A RG + R S R R G SR P R S R P R RS +
Sbjct: 554 SRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRR-----RSRSRT 608
Query: 614 DDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPG----TREPCPA 669
+G + P R+ R P R+ SPA R+S + + P +R PA
Sbjct: 609 PARRG--RSRSRTPARRRSRTRSPVRRRSRSRSPA--RRSGRSRSRTPARRGRSRSRTPA 664
Query: 670 ----------AQEPAPSEDRNP---------FPVKLRSTSLSLKYRDGASQEVKGVKRYS 710
A+ S R P P + RS S SL R G S +R
Sbjct: 665 RRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSL-VRRGRSHSRTPQRRGR 723
Query: 711 AEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQS 770
+ ER + + ++P ++ +R S + + + P S+ L R+ L S
Sbjct: 724 SGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL-RRSLSGS 782
Query: 771 FTLPHQPA--PPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWIT 828
P Q + PP R +P+ + P RR S PP P T
Sbjct: 783 SPCPKQKSQTPPRR---SRSGSSQPKAKSRTPPRRSRSSSSPP----------PKQKSKT 829
Query: 829 VTRQKRRGTLDQPPNQEDKPGARTLKSEP--GKQAKVPER 866
+RQ + P + P + + P +Q+ P+R
Sbjct: 830 PSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQR 869
Score = 66.2 bits (160), Expect = 1e-10
Identities = 157/744 (21%), Positives = 241/744 (32%), Gaps = 93/744 (12%)
Query: 146 KRGEDAGMSSEDDGLPRSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAP 205
+R A DGLPR+P S G ++ +P S S S + D
Sbjct: 1417 ERSSSASSPEMKDGLPRTPSRRS---RSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT- 1472
Query: 206 VADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEEN- 264
P+ S D+S L PR + S S L++ TP+ E +
Sbjct: 1473 ------PSRGRSECDSSPEPKALPQTPRPR--------SRSPSSPELNNKCLTPQRERSG 1518
Query: 265 -----EEKPLLEVSPEERPSSG---QQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSS 316
++K + +R SG + DV P P+ + P A+ R Q S
Sbjct: 1519 SESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRS- 1577
Query: 317 ALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAP 376
G P D SR +P + S+P ++ +P + P Q G
Sbjct: 1578 ------RSGSSPEVDSKSR-LSPRRSRSGSSPEVKDKPRAAPRA----------QSGSDS 1620
Query: 377 PAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDT---TPPETDPAATSEAPSARDGPER 433
P APA + P+ PEG + + PE P + + +R PE
Sbjct: 1621 SPEPKAPAPRALPRRSRSGSSSKGRGPS--PEGSSSTESSPEHPPKSRTARRGSRSSPE- 1677
Query: 434 SVPKEAEPTPPVLPDEEKGPPGPAPEPEREAE-TEPERGAGTEPE-RIGTEPSTAPAPSP 491
PK TPP + +PE R+A + R A + PE R T P +PS
Sbjct: 1678 --PKTKSRTPP-----RRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSV 1730
Query: 492 PAPKSCLKHRPA---AASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAP 548
+P+ K R + ++ P SP P P L + R K
Sbjct: 1731 SSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSP--SPKPRGLQRSRSRSRREKTRTTRRR 1788
Query: 549 PAGAERAAPERKAERGGAELR-------GAKKFSVSSCRARPRPGVSRPLERASGRLPLA 601
+ R+ +R + R G+ S S R SR S P +
Sbjct: 1789 DRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848
Query: 602 RSGPVWRSEAALDDLQGLPEPQHAKPGP-RKLAERGPQDSGDRAASPAGPRKSPQEAAAA 660
R RS + A P R+ R P S R+ S P + +
Sbjct: 1849 RK----RSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRT 1904
Query: 661 PGTREPCPAAQEPAP---SEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLER 717
TR + P S R P + RS S + R + V R + R
Sbjct: 1905 SVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPP 1964
Query: 718 SLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQP 777
+ P+ T R +P + + ++R + P+ + + P
Sbjct: 1965 VTRRRSRSRTSPI-TRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP 2023
Query: 778 APPDAGPGERE---PRKEPRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKR 834
R PRK R+ +RR + P A G + + P + R+
Sbjct: 2024 PAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPP---AIRRRSA 2080
Query: 835 RGTLDQ------PPNQEDKPGART 852
G+ PP + G+RT
Sbjct: 2081 SGSSSDRSRSATPPATRNHSGSRT 2104
Score = 63.9 bits (154), Expect = 7e-10
Identities = 133/615 (21%), Positives = 217/615 (35%), Gaps = 61/615 (9%)
Query: 182 SVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMR 241
S +SPD V + +S+ S +S PV D + P S + S++ ++K R+ R
Sbjct: 1384 SELSPDAVEKAGMSSNQSISS--PVLD-AVPRTPSR--ERSSSASSPEMKDGLPRTPSRR 1438
Query: 242 RLSSRAQSESLSDLTCTPEEEE-NEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLP 300
S S L D + TP + P ++ P PS G+ + D PEP P
Sbjct: 1439 --SRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT-PSRGRSEC--DSSPEPKALPQTP 1493
Query: 301 PPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATP--ELAEPESAPTLRVEPPSPP 358
P L + G D + TP + + S+ L V+P + P
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 359 EGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPETDP 418
+ D +A P + + SP + G + + P
Sbjct: 1554 Q---ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSR--SGSSPEVKDKP 1608
Query: 419 AATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPP-----GPAPEPEREAETEPERGAG 473
A AP A+ G + S P+ P P LP + GP+PE E+ PE
Sbjct: 1609 RA---APRAQSGSDSS-PEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664
Query: 474 TEPERIGTEPSTAP---APSPP-------APKSCLKHRPAAASEGPAASPPLAAAESPPV 523
+ R G+ S P + +PP +P+ K R + S ++SP + P
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRH 1724
Query: 524 EPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARP 583
P E A E+ ++ R + R+ + RG ++ S R +
Sbjct: 1725 RRSPSVSSPEPA--EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKT 1782
Query: 584 RPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAER--GPQDSG 641
R +R +R+ +R RS + + + H++ R+ + R + G
Sbjct: 1783 R--TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRG 1840
Query: 642 DRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAP---SEDRNPFPVKLRSTSLSLKYRDG 698
P ++S + AP R A+ PA S R P + RS S R
Sbjct: 1841 RSRTPPTSRKRSRSRTSPAPWKRSRSRAS--PATHRRSRSRTPLISRRRSRS-----RTS 1893
Query: 699 ASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALR---GTRAPSDQGKGKARPP-- 753
+ R S R RS + T P R +R P+ + + ++R P
Sbjct: 1894 PVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPV 1953
Query: 754 ---EPLSSKPPLPRK 765
S PP+ R+
Sbjct: 1954 TRRRSRSRTPPVTRR 1968
Score = 55.5 bits (132), Expect = 2e-07
Identities = 108/494 (21%), Positives = 168/494 (34%), Gaps = 87/494 (17%)
Query: 471 GAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPP--------LAAAESPP 522
G+ +P+R E + PAP PP P S ++ ++ S P + + SP
Sbjct: 148 GSSFDPQRRARE-AKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPR 206
Query: 523 VEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKK--------- 573
E S + + K + +P ++R + ++K +R + K
Sbjct: 207 RERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSA 266
Query: 574 ---FSVSSCRARPRPGVSRPLERA-SGRLPLARSGPVWRSEAALDD-----LQGLPEPQH 624
S + R+R R ++ A +GR P SG +A + Q P+
Sbjct: 267 DSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326
Query: 625 AKPGPRKLAERGPQDSGDRAA---------SPAGPRK-------------SPQEAAAAPG 662
A P E +D +++A S GP SPQ A P
Sbjct: 327 ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPL 386
Query: 663 TREPCPAAQEPAPSEDRNP--FPVKLRSTSLS---------LKYRDGASQEVKGVKRYSA 711
++EP E +P+ DR+P P KL +S S K AS + K A
Sbjct: 387 SQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPA 446
Query: 712 EVRLERSLTVLPKEEKCPLGTA---------PALR--GTRAPSDQGKGKARPPEPL---- 756
R ++ P + G A P+ R +R+P+ +G++R P
Sbjct: 447 P-GSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH 505
Query: 757 --SSKPPLPRKPLLQSFTLPHQP-----APPDAGPGEREPRKEPRTAEKRPLRRGAEKSL 809
S P R Q + P + PG R R R RRG S
Sbjct: 506 SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSR 565
Query: 810 PPAATGPGADGQPA----PPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPE 865
PA G PA T R++ R + AR +S A+
Sbjct: 566 SPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS 625
Query: 866 RGQEPVKQADFVRS 879
R + PV++ RS
Sbjct: 626 RTRSPVRRRSRSRS 639
Score = 55.1 bits (131), Expect = 3e-07
Identities = 172/863 (19%), Positives = 279/863 (32%), Gaps = 144/863 (16%)
Query: 147 RGEDAGMSSEDDGL-PRSPPEMSLLHDVGPGTTIKVSVVSPDHVS------------DST 193
R +G SS D + P +PP S + P +K +S DS
Sbjct: 966 RYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSL 1025
Query: 194 VSARISDNSL-APVADFSYPAESSSCLDNSAAKHKLQVKPRNQR---SSKMRRLSSRAQS 249
V + SL A V + P ES + + K + Q P ++ S ++R+ S + S
Sbjct: 1026 VQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPS 1085
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARR 309
T P+ E++ + + DRG P G +
Sbjct: 1086 LQSKSQTSPKGGRSRSSSPVTELA-------SRSPIRQDRGEFSASPML---KSGMSPEQ 1135
Query: 310 ARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGP--- 366
+R Q S+ +V+ + G+ SR T E E + P SPP P
Sbjct: 1136 SRFQSDSSSYPTVDSNSLLGQ---SRLETAESKEKMALPPQEDATASPPRQKDKFSPFPV 1192
Query: 367 ---------------------DGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTA 405
G E P + + EE++ E P
Sbjct: 1193 QDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQI 1252
Query: 406 IPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVL-----PDEEKGPPGPAPEP 460
+ + E + +P + P S+ + + L P GP P
Sbjct: 1253 LSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSP 1312
Query: 461 E-REAETEP--ERGAGTEPE-----RIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
E +E P E G+ E +GTE +T + +
Sbjct: 1313 EHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLN---------------G 1357
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAK 572
P L E+ P SLD + + +E P E+A L
Sbjct: 1358 PFLNQLETDP------SLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVP 1411
Query: 573 KFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQH---AKPGP 629
+ + R R S ++ R P RS S L D G P + PG
Sbjct: 1412 R---TPSRERSSSASSPEMKDGLPRTPSRRSRS--GSSPGLRDGSGTPSRHSLSGSSPGM 1466
Query: 630 RKLAERGPQDSGDRAASPAGPRKSPQ------EAAAAPGTREPCPAAQEPAPSEDRNPFP 683
+ + R P S P+ PQ + ++P C Q + +
Sbjct: 1467 KDIP-RTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLE-------RSLTVLPKEEKCPLGTAPAL 736
+ T L + R G+SQE+ S + R E ++ T P ++ G++P +
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV 1585
Query: 737 -----------RGTRAPSDQGKGKARP---------PEPLSSKP-PLPRKPLLQSFTLPH 775
R +P + K +A P PEP + P LPR+ S +
Sbjct: 1586 DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGR 1645
Query: 776 QPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPP---AATGPGADGQPAPPWITVTRQ 832
P+P + E P P++ R RRG+ S P + T P + P +TR+
Sbjct: 1646 GPSPEGSSSTESSPEHPPKS---RTARRGSRSSPEPKTKSRTPPRRRSSRSSP--ELTRK 1700
Query: 833 KRRGTLDQPPNQEDKPGARTLKSEPGKQAKVPE-RGQEPVKQADFVRSKSFLITPVKPAV 891
R + + + +RT P + + P EP +++ R + +P
Sbjct: 1701 ARLSRRSRSASSSPETRSRT----PPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT 1756
Query: 892 DRKQGAKLNFKEGLQRGISLSHQ 914
R+ + GLQR S S +
Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRR 1779
Score = 53.5 bits (127), Expect = 9e-07
Identities = 96/466 (20%), Positives = 157/466 (33%), Gaps = 42/466 (9%)
Query: 162 RSPPEMSLLHDVGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDN 221
R+P ++ L G GT + S T A S N + P + A +++ ++
Sbjct: 2301 RTPAALAALSLTGSGTPPTAANYPS---SSRTPQAPASANLVGPRS-----AHATAPVNI 2352
Query: 222 SAAKHKLQVKPRNQRSSKMRRLSSRAQSESLS-DLTCTPEEEENEEKPLLEVSPEERPSS 280
+ ++ + P + S++M S A S L+ PLL+ + P S
Sbjct: 2353 AGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPS 2412
Query: 281 G--QQDVAPDRGPEPG------PPAPLPPPGGARARR----ARLQHSSALTASVEEGGVP 328
Q + +R P P P L PP + R A S L A
Sbjct: 2413 APSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGS 2472
Query: 329 GEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKA 388
S AT + + L V P P P G P+ A K
Sbjct: 2473 QSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPP---ASTGAQQPSALAALQPAKE 2529
Query: 389 EEVVCAPEDVASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTP-PVLP 447
+ +S ++ ++ ++ SE S PE ++ + PTP P
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEA 2589
Query: 448 DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE 507
E PP P P + + + + + S++ + S + S +++S
Sbjct: 2590 VREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649
Query: 508 GPAASPPLAAAE-SPPVEPGPGSLDAEAAAPERP-------------KAERAEAPPAGAE 553
PA P A + + P +P PG + + +P +P ER P +
Sbjct: 2650 SPAKPGPQALPKPASPKKPPPG--ERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707
Query: 554 RAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLP 599
R +ERG + S S R R P RP+ S R P
Sbjct: 2708 RDQQSSSSERGSRRGQRGDSRSPSHKRRRETPS-PRPMRHRSSRSP 2752
Score = 51.2 bits (121), Expect = 5e-06
Identities = 117/542 (21%), Positives = 175/542 (32%), Gaps = 64/542 (11%)
Query: 296 PAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAE---PESAPTLRV 352
PAP+P A A L S AS + + P LA+ P +A + +
Sbjct: 2212 PAPVPLMSLRTAPAANLA-SRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNL 2270
Query: 353 EPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTT 412
P P A P P APA + A A+ ++ T
Sbjct: 2271 ASPRTAVAP--------SAVNLADPRTPTAPAVNLA-----GARTPAALAALSLTGSGTP 2317
Query: 413 PPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEP---- 468
P + ++S P A P+ A T PV + AP A P
Sbjct: 2318 PTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSG 2377
Query: 469 -------------ERGAG-TEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE-GPAASP 513
ER +G T P + S P +P + + P+ +S G A S
Sbjct: 2378 ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
Query: 514 PLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKK 573
L PP + P S A + + P AG++ + G +
Sbjct: 2438 SLL----PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSS------GAVATTTSSA 2487
Query: 574 FSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLA 633
+ + P PGV + P A +G + +AL LQ E + + +
Sbjct: 2488 GDHNGMLSVPAPGVPH----SDVGEPPASTGA--QQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 634 ERGPQDSGDRAASPAGPRKSPQEAAAAPGTRE--------PCPAAQEPAPSEDR--NPFP 683
S ++S +G S E ++ P E P PA +E A E R P P
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKE-AVREGRPPEPTP 2600
Query: 684 VKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRA-P 742
K + S S +S S+ S + +PA G +A P
Sbjct: 2601 AKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALP 2660
Query: 743 SDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLR 802
K P E S P P L S +L + P + PR + ++ +R R
Sbjct: 2661 KPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSR 2720
Query: 803 RG 804
RG
Sbjct: 2721 RG 2722
Score = 44.7 bits (104), Expect = 4e-04
Identities = 107/551 (19%), Positives = 193/551 (35%), Gaps = 84/551 (15%)
Query: 354 PPSPPEGPPNPGPDGGKQD---GEAPP----AGPCAPATDKAEEVVCAPEDVASPFPTAI 406
P + PP G Q PP + P K++ +SP P +
Sbjct: 786 PKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK-V 844
Query: 407 PEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVL-------------PDEEKGP 453
G TPP + +A P+R E+ P P + P K
Sbjct: 845 KSG--TPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSS 902
Query: 454 PGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPS------------PPAPKSCLKHR 501
P P R + +P+ A P + S++P+PS +P S ++ R
Sbjct: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESR 962
Query: 502 --PAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPP----AGAERA 555
P + G ++ E+PP + GS+ PK +A+ PP +G++
Sbjct: 963 LLPRYSHSGSSSPDTKVKPETPPRQSHSGSIS------PYPKV-KAQTPPGPSLSGSKSP 1015
Query: 556 APERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDD 615
P+ K++ + + ++ PG S + +++ P RS+ + +
Sbjct: 1016 CPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPE 1075
Query: 616 LQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAP 675
++ + P + ++ P+ R++SP + A+ +P ++ + P
Sbjct: 1076 VR---QSHSESPSLQSKSQTSPKGGRSRSSSPV-----TELASRSPIRQDRGEFSASPML 1127
Query: 676 SEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPA 735
+P + +S S S D S + RLE + E K + P
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNS--------LLGQSRLETA------ESKEKMALPPQ 1173
Query: 736 LRGTRAPSDQGKGKARPPEPLSSKP--PLPRKPLLQSFTLPHQPAPPDAGPGEREPRKE- 792
T +P Q K K P P+ +P L K L+ T P + + + P +E
Sbjct: 1174 EDATASPPRQ-KDKF-SPFPVQDRPESSLVFKDTLR--TPPRERSGAGSSPETKEQNSAL 1229
Query: 793 PRTAEKRPLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGART 852
P +++ L EKS PA GQ + ++ + P E++P
Sbjct: 1230 PTSSQDEELMEVVEKSEEPA-------GQILSHLSSELKEMSTSNFESSPEVEERPAVSL 1282
Query: 853 LKSEPGKQAKV 863
+ QA +
Sbjct: 1283 TLDQSQSQASL 1293
Score = 37.0 bits (84), Expect = 0.089
Identities = 112/551 (20%), Positives = 190/551 (34%), Gaps = 65/551 (11%)
Query: 185 SPDHVSDSTVSARISDNSLAPVADFSYPAESSSCLDNSAA--KHKLQVKPRNQRSSKMRR 242
S + S +S+R S + +P + L S+ K K Q PR RS
Sbjct: 745 SSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSG---- 800
Query: 243 LSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPP- 301
SS+ +++S + P + P P+++ + + P P + PP
Sbjct: 801 -SSQPKAKSRTP----PRRSRSSSSP----PPKQKSKTPSRQSHSSSSPHPKVKSGTPPR 851
Query: 302 PGGARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGP 361
G + +A Q + S E DP + TP + RV+ +PP
Sbjct: 852 QGSITSPQANEQSVTPQRRSCFESS---PDPELKSRTPSRHSCSGSSPPRVKSSTPPRQS 908
Query: 362 PN--------------PGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIP 407
P+ P P+ + T + V +V S
Sbjct: 909 PSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYS 968
Query: 408 EGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETE 467
++ P+T + + G PK TPP G P P+ E+ ++
Sbjct: 969 HSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPP--GPSLSGSKSPCPQ-EKSKDSL 1025
Query: 468 PERGAGTEPERIGTEPSTAPAPSPPAPKSC-LKHRPAAASE--GPAASPPL--AAAESPP 522
+ G+ G + ST P S S LK + + + +SP + + +ESP
Sbjct: 1026 VQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP- 1084
Query: 523 VEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRAR 582
SL +++ + R+ +P +P R+ +RG K +S ++R
Sbjct: 1085 ------SLQSKSQTSPKGGRSRSSSPVTELASRSPIRQ-DRGEFSASPMLKSGMSPEQSR 1137
Query: 583 ------PRPGVSRPLERASGRLPLARSGPVWRSEAAL---DDLQGLPEPQHAKPGPRKLA 633
P V RL A S + + AL +D P Q K P +
Sbjct: 1138 FQSDSSSYPTVDSNSLLGQSRLETAES----KEKMALPPQEDATASPPRQKDKFSPFPVQ 1193
Query: 634 ERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSL 693
+R P+ S + P + A ++P T+E A P S+D V +S +
Sbjct: 1194 DR-PESSLVFKDTLRTPPRERSGAGSSPETKEQNSAL--PTSSQDEELMEVVEKSEEPAG 1250
Query: 694 KYRDGASQEVK 704
+ S E+K
Sbjct: 1251 QILSHLSSELK 1261
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 81.6 bits (200), Expect = 3e-15
Identities = 126/488 (25%), Positives = 180/488 (36%), Gaps = 73/488 (14%)
Query: 338 TPELAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPED 397
+P L E + P EP S P G E+P P P + V +PE
Sbjct: 108 SPPLPEHQKIPCNSAEPKSIPALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPE- 166
Query: 398 VASPFPTAIPEGDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPA 457
+ +P P+ PE A+ +P P +SVP + + +K P P+
Sbjct: 167 LQTPLPS---------PEPSKPASVSSPE----PPKSVP---------VCESQKLAPVPS 204
Query: 458 PEPEREAETEPERGAGT----EPERIGTEPSTAPAPSPPAPKS-CLKHRPAAASEGPAAS 512
PEP++ A PE T +P++ P T PS +P+S L P PAAS
Sbjct: 205 PEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPAAS 264
Query: 513 P---PLAAAESP-PVEPGPGSLDA-----EAAAPERPKAERAEAP------PAGAERAAP 557
P A SP P +P P A +PE + A +P P G+ R
Sbjct: 265 PESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWK 324
Query: 558 ERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQ 617
+ G SVS +P P VS + + + S W+S +
Sbjct: 325 SNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSV----SSASWKSSSVSPSSW 380
Query: 618 GLP--EPQHAKPGPRKLAERGPQDSGD--RAASPAGPRKSPQEAAAAPGTREPC--PAAQ 671
P P+ K GP +L + P S + +A P P +P R P P +
Sbjct: 381 KSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELR 440
Query: 672 EPAPSEDRNPFPVKLRSTS-LSLKYRDGASQEVKG-VKRYSAEVRLERSLTVLPKEEKCP 729
+P+ S D R TS SL + + G + + +E V P+ K
Sbjct: 441 KPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRK-- 498
Query: 730 LGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGER-- 787
G PS+ K + +P+ S PRKP L F P + APP A P R
Sbjct: 499 -------PGPSGPSESPKAASDIWKPVLSIDTEPRKPAL--FPEPAKTAPP-ASPEARKR 548
Query: 788 ----EPRK 791
EPRK
Sbjct: 549 ALFPEPRK 556
Score = 73.9 bits (180), Expect = 7e-13
Identities = 110/449 (24%), Positives = 161/449 (35%), Gaps = 59/449 (13%)
Query: 230 VKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEEENEEKPLLEVSPEER---PSSGQQDVA 286
+ P + + + + L + +S TP KP SPE P Q +A
Sbjct: 141 LSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLA 200
Query: 287 PDRGPEPGPPAPLPPPG-GARARRARLQHSSALTASVEEGGVPGEDPSSRPATPE----- 340
P PEP PAP+ P A + Q S ++ + A+PE
Sbjct: 201 PVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPS 260
Query: 341 -LAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVA 399
A PES + R P P + P+ P+ K P +P + P
Sbjct: 261 PAASPESRKSARTTSPEPRKPSPSESPEPWK------PFPAVSPEPRR-------PAPAV 307
Query: 400 SPFP-TAIPEGDTTPPETDPAATS-------EAPSARDGPERSVPKEA----EPTPPVLP 447
SP P G P +++P+A+S APS GP + +P + +PTP V
Sbjct: 308 SPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSS 367
Query: 448 DEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASE 507
K +P + PE PE TAP SP K+ P
Sbjct: 368 ASWKS-SSVSPSSWKSPPASPESWKSGPPEL----RKTAPTLSPEHWKAVPPVSPELRKP 422
Query: 508 GPAASPPL-AAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGA 566
GP SP + + A SP + GS D +P++ K PA + ++ + G
Sbjct: 423 GPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTS-----PASLDFPESQKSSRGGSP 477
Query: 567 ELRGAKKFSVSSCRARP---RPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQ 623
+L + F P +PG S P E P A S +W+ ++D P
Sbjct: 478 DLWKSSFFIEPQKPVFPETRKPGPSGPSES-----PKAAS-DIWKPVLSIDT---EPRKP 528
Query: 624 HAKPGPRKLAERGPQDSGDRAASPAGPRK 652
P P K A ++ RA P PRK
Sbjct: 529 ALFPEPAKTAPPASPEARKRALFPE-PRK 556
Score = 43.9 bits (102), Expect = 7e-04
Identities = 103/481 (21%), Positives = 156/481 (32%), Gaps = 102/481 (21%)
Query: 429 DGPERSVPKEAEPTP-PVLPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEPST-A 486
D P+ + KE +P P LP+ +K P AE + E +++G+ S +
Sbjct: 93 DKPKNQLNKETDPVKSPPLPEHQKIPCN-------SAEPKSIPALSMETQKLGSVLSPES 145
Query: 487 PAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAE 546
P P+P P K G SP L ++P P P S A ++PE PK+
Sbjct: 146 PKPTPLTPLEPQK-------PGSVVSPEL---QTPLPSPEP-SKPASVSSPEPPKS---- 190
Query: 547 APPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPV 606
P +++ AP P P P+ S + L+ P
Sbjct: 191 VPVCESQKLAPVPS----------------------PEPQKPAPVSPESVKATLSNPKPQ 228
Query: 607 WRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREP 666
+S + L P + P LA P+ G A+ RKS R
Sbjct: 229 KQSHFP----ETLGPPSASSPESPVLAA-SPEPWGPSPAASPESRKS---------ARTT 274
Query: 667 CPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEE 726
P ++P+PSE P+ K S E R +
Sbjct: 275 SPEPRKPSPSESPEPW---------------------KPFPAVSPEPRRPAPAVSPGSWK 313
Query: 727 KCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGE 786
P G+ R ++ G +P +P S P P KP+ P +P P +
Sbjct: 314 PGPPGSP---RPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKPTPSVSSASW 370
Query: 787 REPRKEPRTAEKRPLRRGAEKSLPP-----AATGPGADGQPAPPWITVTRQKRRGTLDQP 841
+ P + + P + KS PP A T + PP R+ +
Sbjct: 371 KSSSVSPSSWKSPPASPESWKSGPPELRKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEI 430
Query: 842 PNQEDKPGARTLKSEPGKQAKVPERGQEPVKQADFVRSK-------------SFLITPVK 888
+ P R P P++ + DF S+ SF I P K
Sbjct: 431 RSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQK 490
Query: 889 P 889
P
Sbjct: 491 P 491
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 81.3 bits (199), Expect = 4e-15
Identities = 121/445 (27%), Positives = 151/445 (33%), Gaps = 71/445 (15%)
Query: 272 VSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSS-ALTASVEEGG---V 327
VS EE + AP+R P +P A A + + ++ A+ A++ + G V
Sbjct: 889 VSLEEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAV 948
Query: 328 PGEDPS------SRPATPELAEPES--APTLRVEPP----------SPPEGPPNPGPDGG 369
G P + P T E PE P V P S PE P +P
Sbjct: 949 AGFSPEWAALAITVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAA--- 1005
Query: 370 KQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPE--TDPAATSEAPSA 427
P P +PA V PE+ SP A+P PPE T PAA P
Sbjct: 1006 ---AVPTPEEPTSPAA-----AVPTPEEPTSP-AAAVP-----PPEEPTSPAAAVPTPEE 1051
Query: 428 RDGPERSVPKEAEPTPPV----LPDEEKGPPGPAPEPEREAETEPERGAGTEPERIGTEP 483
P +VP EPT P P+E P P PE EP A P E
Sbjct: 1052 PTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPE-----EPTSPAAAVPT---PEE 1103
Query: 484 STAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAE 543
T+PA + P P+ PAAA P AAA P EP + A A A
Sbjct: 1104 PTSPAAAVPTPEE--PASPAAAVPTPEEPASPAAAVPTPEEP---AFPAPAVPTPEESAS 1158
Query: 544 RAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPL--- 600
A A P E A+P A + P V P +
Sbjct: 1159 AAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSP 1218
Query: 601 ARSGPVWRSEAALDDLQGLPE---------PQHAKPGPRKLAERGPQDSGDRAASPAGPR 651
A S P A+L PE P +P A P++ AAS P
Sbjct: 1219 AASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSSPAASVPTPE 1278
Query: 652 KSPQEAAAAPGTREPC-PAAQEPAP 675
+ AAA EP PAA P P
Sbjct: 1279 EPASPAAAVSNLEEPASPAAAVPTP 1303
Score = 77.0 bits (188), Expect = 8e-14
Identities = 109/428 (25%), Positives = 140/428 (32%), Gaps = 66/428 (15%)
Query: 173 VGPGTTIKVSVVSPDHVSDSTVSARISDNSLAPVADFS---------YPAESSSCLDNSA 223
V GT +V SP+ + + V+A I+ ++ VA FS P
Sbjct: 916 VPEGTAAVAAVSSPEETAPA-VAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPEGP 974
Query: 224 AKHKLQVKPRNQRSSKMRRLSSRAQSESLSDLTCTPEEE----------ENEEKPLLEVS 273
V + + R+S+ + S + TPEE E P V
Sbjct: 975 VTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1034
Query: 274 PEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARRARLQHSSALTASVEEGGVPGEDPS 333
P E P+S V P P A +P P + A + T+ P E S
Sbjct: 1035 PPEEPTSPAAAVPTPEEPT-SPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTS 1093
Query: 334 SRPATPELAEPESAPTLRV----EPPSPPEGPPNPGPDGGKQDGEAPPAGPC--APATDK 387
A P EP S P V EP SP P P P P APA
Sbjct: 1094 PAAAVPTPEEPTS-PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPT 1152
Query: 388 AEEVVCAPEDVASPFPTAIPEGDT-TPPE--------------TDPAATSEAPSAR---- 428
EE A V +P +A P TP E T PAA+ P+A
Sbjct: 1153 PEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATL 1212
Query: 429 ---DGPERSVPKEAEPTPPVL----PDEEKGPPGPAPEPEREAETEPERGAGTEPERIGT 481
P SVP EP P+E P P E E A PE + +
Sbjct: 1213 EEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLE---EPTSSAAAVLTPEELSS 1269
Query: 482 EPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPK 541
++ P P PA + AA S + P AA +P V P A PE P
Sbjct: 1270 PAASVPTPEEPASPA------AAVSNLEEPASPAAAVPTPEVAAIPA---ASVPTPEVPA 1320
Query: 542 AERAEAPP 549
A PP
Sbjct: 1321 IPAAAVPP 1328
Score = 71.6 bits (174), Expect = 3e-12
Identities = 131/545 (24%), Positives = 169/545 (31%), Gaps = 80/545 (14%)
Query: 291 PEPGPP-APLPPPGGARARRARLQ--HSSALTASVEEGGVPGEDPSSRPATPELAEPESA 347
PE G A +P P G A + H L AS+ V E+ A E +
Sbjct: 854 PEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASI----VSLEEEDVTAAAVSAPERATV 909
Query: 348 PTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVV-CAPEDVASPFPTAI 406
P + V S PEG + E PA A + V +PE A I
Sbjct: 910 PAVTV---SVPEGTAAVAAVSSPE--ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPI 964
Query: 407 PEGDTTPP-ETDPAATSEAPSARDGPERSVPKEAEPTPPVL----PDEEKGPPGPAPEPE 461
E D TP PA T AP D V EP P P+E P P PE
Sbjct: 965 TEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPE 1024
Query: 462 REAETEPERGAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESP 521
T P A P T P+ A P+P P S PAAA P P + A +
Sbjct: 1025 EP--TSP--AAAVPPPEEPTSPAAA-VPTPEEPTS-----PAAAV--PTPEEPTSPAAAV 1072
Query: 522 PVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRA 581
P P S A PE P + A P PE
Sbjct: 1073 PTPEEPTSPAAAVPTPEEPTSPAAAVP-------TPEEPTS------------------- 1106
Query: 582 RPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQH-AKPGPRKLAERGPQDS 640
P V P E P + + V E +P P+ A P P A P++S
Sbjct: 1107 -PAAAVPTPEE------PASPAAAVPTPEEPASPAAAVPTPEEPAFPAP---AVPTPEES 1156
Query: 641 GDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGAS 700
A + P +S AAA P E A A E+ + + + + + +
Sbjct: 1157 ASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFT 1216
Query: 701 QEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGTRAPSDQGKGKARPPEPLSSKP 760
V L +++ P+E P P L P+ P E S
Sbjct: 1217 SPAASVPTSEEPASLAAAVS-NPEEPTSPAAAVPTL---EEPTSSAAAVLTPEELSSPAA 1272
Query: 761 PLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKRPLRRGAEKSLPPAATGPGADG 820
+P P +PA P A E P A P + P P
Sbjct: 1273 SVP---------TPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEVPAIPA 1323
Query: 821 QPAPP 825
PP
Sbjct: 1324 AAVPP 1328
Score = 47.8 bits (112), Expect = 5e-05
Identities = 120/511 (23%), Positives = 158/511 (30%), Gaps = 112/511 (21%)
Query: 407 PEGDTTPPETDP---AATSEAPSA--RDG-------PERSVPKEAEPTPPVLPDEEKGPP 454
P+G T +T P A+SE RD PE+ V K A T PVL EE P
Sbjct: 774 PDGVETVNDTKPELNVASSEGGEMERRDSDSFLNIFPEKQVTK-AGNTEPVL--EEWIPV 830
Query: 455 GPAPEPEREAETEPER--GAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAAS 512
P T + A PE GT + PAP A + L P
Sbjct: 831 LQRPSRTAAVPTVKDALDAALPSPEE-GTSIAAVPAPEGTAVVAALV---------PFPH 880
Query: 513 PPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAK 572
+ A +E D AAA P ERA P + PE G
Sbjct: 881 EDILVASIVSLEEE----DVTAAAVSAP--ERATVPAVTV--SVPE-----------GTA 921
Query: 573 KFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAA---LDDLQGLPEPQ------ 623
+ S P V+ + + G +A P W + A + + G PE
Sbjct: 922 AVAAVSSPEETAPAVAAAITQ-EGMSAVAGFSPEWAALAITVPITEEDGTPEGPVTPATT 980
Query: 624 -HAKPGPRKLAER--GPQDSGDRAASPAGPRKSPQEAAAAPGTREP-CPAAQEPAPSEDR 679
HA P A R P++ AA+ P + AAA P EP PAA P P E
Sbjct: 981 VHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPT 1040
Query: 680 NPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAPALRGT 739
+P +P E+ P A A+
Sbjct: 1041 SP-------------------------------------AAAVPTPEE-PTSPAAAVPTP 1062
Query: 740 RAPSDQGKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPPDAGPGEREPRKEPRTAEKR 799
P+ P EP S +P P +P P A E P A
Sbjct: 1063 EEPTSPAAAVPTPEEPTSPAAAVP---------TPEEPTSPAAAVPTPEEPTSPAAAVPT 1113
Query: 800 PLRRGAEKSLPPAATGPGADGQPAPPWITVTRQKRRGTLDQPPNQEDKPGARTLKSEPGK 859
P E+ PAA P + +P T ++ P E+ A P +
Sbjct: 1114 P-----EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEE 1168
Query: 860 QAKVPERGQEPVKQADFVRSKSFLITPVKPA 890
A P + A F + L P PA
Sbjct: 1169 SASPAAAVPTPAESASFAAVVATLEEPTSPA 1199
Score = 38.5 bits (88), Expect = 0.031
Identities = 50/200 (25%), Positives = 63/200 (31%), Gaps = 29/200 (14%)
Query: 250 ESLSDLTCTPEEEENEEKPLLEVSPEERPSSGQQDVAPDRGPEPGPPAPLPPPGGARARR 309
ES S P EE+ +P E S + P P P A
Sbjct: 1155 ESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPA-----AMV 1209
Query: 310 ARLQHSSALTASVEEGGVPG---------EDPSS-RPATPELAEPESAPTLRVEPP---S 356
A L+ ++ ASV P E+P+S A P L EP S+ + P S
Sbjct: 1210 ATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS 1269
Query: 357 PPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFPTAIPEGDTTPPET 416
P P P PA P A A EE V +P AIP PE
Sbjct: 1270 PAASVPTP----------EEPASPAA-AVSNLEEPASPAAAVPTPEVAAIPAASVPTPEV 1318
Query: 417 DPAATSEAPSARDGPERSVP 436
+ P + VP
Sbjct: 1319 PAIPAAAVPPMEEVSPIGVP 1338
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 80.9 bits (198), Expect = 5e-15
Identities = 131/520 (25%), Positives = 187/520 (35%), Gaps = 97/520 (18%)
Query: 136 PPPPPGGLPAKRGEDA-GMSSEDDGLPRSPPE--MSLLHDVGPGTTIKVSVVSPDHVSDS 192
PPPPP G P A +S++ L R+ P+ +LL D+ GT ++ D +
Sbjct: 13 PPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAPQ 72
Query: 193 TVSARISDNSLAPVADFSYPAESSSCLDNSAAKHKLQVKPRNQRSSKMRRL----SSRAQ 248
S++ ++ A+ + A + L + A ++P QR + SRA
Sbjct: 73 IESSKGTNKEGGGSAN-TRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAP 131
Query: 249 SESLSDLTCTPEEEENEEKPLL-EVSPEERPSS---GQQDVAPDRGPEPGPPAPLPPPGG 304
S L + T + PL+ SP +S G AP R P PP P PPP
Sbjct: 132 SPRLPNKTIS--------GPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPP 183
Query: 305 ARARRARLQHSSALTASVEEGGVPGEDPSSRPATPELAEPESAPTLRVEPPSPPEGPPNP 364
S T V G P ++ P +A P PP PP PP P
Sbjct: 184 PPLPPPLPSSSPIKTPLVSPPG-----PLTKGNLPVVAPPVPC----APPPPPPPPPPTP 234
Query: 365 GPDGGKQDGEAPPAGPCAPATDKAEEVVCAP---EDVASPFP-------------TAIPE 408
PP P + +DKA + AP + P P A P
Sbjct: 235 -----------PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPA 283
Query: 409 GDTTPPETDPAATSEAPSARDGPERSVPKEAEPTPPVLPDEEKGPPGPAPEPEREAETEP 468
D P P P A P S+P A P P V E PP P P +A
Sbjct: 284 QDAQEPPAPPPPL--PPYASCSPRASLP--APPLPGVNSSSETPPPLPPKSPSFQA---- 335
Query: 469 ERGAGTEPERIGTEPSTAPAPSPPAPKSCL---KHRPAAASEGPAASPPLAAAESPPVEP 525
P++ G + AP P+PP + L +H A G PP A SP E
Sbjct: 336 ------PPQKAGAQALPAP-PAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTEL 388
Query: 526 GPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG--AKKFSVSSCRARP 583
S A A P + P + G + KF+ S P
Sbjct: 389 SSKSQQATAWTPTQ----------------QPGGQLRNGSLHIIDDFESKFTFHSVEDFP 432
Query: 584 RPGVSRPLERA-SGRLPLARS-GPVWRSEA---ALDDLQG 618
P +P ++ ++P +R+ GP ++EA + DD++G
Sbjct: 433 PPDEYKPCQKIYPSKIPRSRTPGPWLQAEAVGQSSDDIKG 472
Score = 72.8 bits (177), Expect = 1e-12
Identities = 116/426 (27%), Positives = 149/426 (34%), Gaps = 83/426 (19%)
Query: 291 PEPGPP--APLPPPGGA--------RARRARLQHSSALTASVEEGGVPGEDPSSRPATPE 340
P P PP AP PPP A RRA + SAL A +++G +R
Sbjct: 12 PPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQG--------TRLRKVT 63
Query: 341 LAEPESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPP------AGPCAPATDKAEEVVCA 394
SAP + + EG G + PP AG + V
Sbjct: 64 QINDRSAPQIESSKGTNKEG----GGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAG 119
Query: 395 PEDVASPFPTA----IPEGDTTPPETDPAA-----TSEAP-SARDGPER-SVPKEAEPTP 443
+ P A +P + P PA+ TSEA +AR P R +VP PTP
Sbjct: 120 GKTGQGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTP 179
Query: 444 PVLPDEEKGPPGPAPEPEREAETEPERGA--GTEPERIGTEPSTAPAPSPPAPKSCLKHR 501
P P PP P+ P + P G P P P P PP P +
Sbjct: 180 PP-PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLP 238
Query: 502 PAAASEGPAASPPLAAAESPPVEP--------GPGSLDAEAAAPERPKAERAEAPPAGAE 553
PA+ A P LA PP+ P G L AE A+P A+ A+ PPA
Sbjct: 239 PASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASP----AQDAQEPPAPPP 294
Query: 554 RAAPERKAERGGAELRGAKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAAL 613
P A +S A P PGV+ E PL P +++
Sbjct: 295 PLPPY------------ASCSPRASLPAPPLPGVNSSSETPP---PLPPKSPSFQAPPQK 339
Query: 614 DDLQGLPEPQHAKPG-----PRKLAERGPQDSGDRAASPAGPRKSP--------QEAAAA 660
Q LP P A PG +K R G PA P +SP Q+A A
Sbjct: 340 AGAQALPAPP-APPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAW 398
Query: 661 PGTREP 666
T++P
Sbjct: 399 TPTQQP 404
Score = 44.3 bits (103), Expect = 6e-04
Identities = 102/415 (24%), Positives = 132/415 (31%), Gaps = 97/415 (23%)
Query: 487 PAPSPPAPKSCLKHRPAAASEGPAASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAE 546
P P PP P P PPL A PP P S D + PK A
Sbjct: 2 PVPPPPPPPL------------PPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSAL 49
Query: 547 APPAGAERAAPERKA----ERGGAELRGAKKFSVSSCRARPRPGVSRPL---ERASGRLP 599
A ++ RK +R ++ +K + + G S P + +G P
Sbjct: 50 L--ADIQQGTRLRKVTQINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFP 107
Query: 600 LARSGPVWRSEAALDDLQGLPEPQHAKPGPRKLAERGPQDS-GDRAASPAGPRK-SPQEA 657
+ R A D+ G Q PG R + R P + PA PR + EA
Sbjct: 108 VLRP-------AGQRDVAGGKTGQG--PGSRAPSPRLPNKTISGPLIPPASPRLGNTSEA 158
Query: 658 AAAPGTREP---CPAAQEPAPSEDRNPFPVKLRSTSLSLKYRDGASQEVKGVKRYSAEVR 714
A T P PA P P P P L S+S
Sbjct: 159 HGAARTAPPRPNVPAPPPPTPPPPPPPLPPPLPSSS-----------------------P 195
Query: 715 LERSLTVLPKEEKCPL--GTAPALRGTRAPSDQGKGKARPPEPLSSKPPLPR-------- 764
++ L P PL G P + AP PP P + PPLP
Sbjct: 196 IKTPLVSPPG----PLTKGNLPVV----APPVPCAPPPPPPPPPPTPPPLPPASVLSDKA 247
Query: 765 -KPLLQSFTLPHQP-----APPDAGPG-EREPRKEPRTAEKRPLRRGAEKSLPPAATGPG 817
KP L LP P PP PG + EP + A++ P LPP A+
Sbjct: 248 VKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPP---APPPPLPPYASCSP 304
Query: 818 ADGQPAPPWITVTRQK--------RRGTLDQPPNQEDKPGARTLKSEPGKQAKVP 864
PAPP V + + PP K GA+ L + P P
Sbjct: 305 RASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP---QKAGAQALPAPPAPPGSQP 356
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.306 0.127 0.372
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,193,095
Number of Sequences: 37866
Number of extensions: 3983466
Number of successful extensions: 51917
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 496
Number of HSP's successfully gapped in prelim test: 3083
Number of HSP's that attempted gapping in prelim test: 18558
Number of HSP's gapped (non-prelim): 19608
length of query: 962
length of database: 18,247,518
effective HSP length: 112
effective length of query: 850
effective length of database: 14,006,526
effective search space: 11905547100
effective search space used: 11905547100
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.