Guide to the Human Genome
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Search of human proteins with 239741486

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239741486 PREDICTED: hypothetical protein XP_002342213 [Homo
sapiens]
         (233 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239741486 PREDICTED: hypothetical protein XP_002342213 [Homo ...   478   e-135
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    52   6e-07
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    52   6e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         51   7e-07
gi|117938768 GNAS complex locus alex [Homo sapiens]                    49   5e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    48   8e-06
gi|145386517 phostensin [Homo sapiens]                                 47   1e-05
gi|199559805 phostensin [Homo sapiens]                                 47   1e-05
gi|163965366 nascent polypeptide-associated complex alpha subuni...    47   1e-05
gi|4504733 insulin receptor substrate 4 [Homo sapiens]                 47   2e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        47   2e-05
gi|223633935 hypothetical protein LOC254427 [Homo sapiens]             46   3e-05
gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]         46   3e-05
gi|154146199 sal-like 3 [Homo sapiens]                                 45   4e-05
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   45   5e-05
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   45   5e-05
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   45   5e-05
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    45   5e-05
gi|55741677 SET domain containing 1A [Homo sapiens]                    45   5e-05
gi|146219841 PNMA-like 2 [Homo sapiens]                                45   5e-05
gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo ...    45   7e-05
gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo ...    45   7e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    44   9e-05
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    44   9e-05
gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens]              44   9e-05
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     44   1e-04
gi|239747203 PREDICTED: hypothetical protein LOC643965 [Homo sap...    44   2e-04
gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo sap...    44   2e-04
gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sap...    43   2e-04
gi|148747864 JAW1-related protein isoform a [Homo sapiens]             43   2e-04

>gi|239741486 PREDICTED: hypothetical protein XP_002342213 [Homo
           sapiens]
          Length = 233

 Score =  478 bits (1230), Expect = e-135
 Identities = 233/233 (100%), Positives = 233/233 (100%)

Query: 1   MFVPDLVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL 60
           MFVPDLVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL
Sbjct: 1   MFVPDLVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL 60

Query: 61  LTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPP 120
           LTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPP
Sbjct: 61  LTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPP 120

Query: 121 SPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGW 180
           SPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGW
Sbjct: 121 SPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGW 180

Query: 181 AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
           AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL
Sbjct: 181 AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 74/265 (27%), Positives = 93/265 (35%), Gaps = 50/265 (18%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPS--PPRCAKTQLTPPAIRSCPLPPEEDLLTPQGS--- 66
           S P +  VQ+P F        SPS  PP  A   L  P ++  P PP    ++P  +   
Sbjct: 441 SPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 499

Query: 67  -------APRLLLGEASLTSPLALIPP------SEPQHSPSKSRALCNRGLRSTSRCTQQ 113
                  AP L L +    +P AL  P      S P   P ++    +  L  +   T  
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559

Query: 114 GLPSVPP---SPLTPLPPSP------TAPRRSQYPSP-----GSRVGRGLGTG------- 152
             P  PP   +PL  +PPSP       APRR   P P     G R+   L  G       
Sbjct: 560 --PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 617

Query: 153 -------RGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGP 205
                     LA   + +   PE   G      G AA+SP   A   A   A   RG  P
Sbjct: 618 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 677

Query: 206 AREGSGAPSGLGSRAVPVTAPRLRD 230
                GAP G      P T P   D
Sbjct: 678 PLAFRGAP-GAPLPWPPATGPGSAD 701



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 67/233 (28%), Positives = 90/233 (38%), Gaps = 18/233 (7%)

Query: 12  SKPAASGVQSPTFHGSGRQTASP--SPPRCAKTQLTPPAIRSCPLPPEEDLLT----PQG 65
           S PA+   Q+P F  S     SP  +PP  A   L  P ++  P PP    L     P  
Sbjct: 533 SPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591

Query: 66  SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRA---LCNRGLRSTSRCTQ-QGLPSVPPS 121
             P   +    LT  LA  PP  P  SPS + +   L      +TS   + +G  S P  
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 651

Query: 122 PLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSR-GRSTGW 180
                PP P A   + +P+  SR        RG      AP   PP    GS  G  T +
Sbjct: 652 GAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPG---APLPWPPATGPGSADGLCTIY 707

Query: 181 AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
               P++  A  AP A   G   G +   + A +G G+ +      RL + PL
Sbjct: 708 ETEGPES--ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 758



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 59/212 (27%), Positives = 75/212 (35%), Gaps = 37/212 (17%)

Query: 4   PDLVNQCSSKPAASGVQSPTFHGSGRQTAS----PSPPRCAKTQLTPPAIRSCPLPPEED 59
           P  +    S PA    Q+ T  GS    A+    PSPP        P A  +  LPP + 
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 407

Query: 60  LLTPQGSAPRLLLGEASLTSPLALI----------PPSEPQHSPSKSRALCNRGLRSTSR 109
             +P  S P   L   S  +P AL           PPS P  +P    A  +  +  ++ 
Sbjct: 408 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--SPPVSPSAT 465

Query: 110 CTQQGLPS-------VPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP 162
              Q  PS       VPPSP    P SP+A    Q P P              LA     
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP--------------LAAPPLQ 511

Query: 163 SKEPPERACGSRGRSTGWAASSPKTHAAGQAP 194
             +PP +A  +       A  SP     GQAP
Sbjct: 512 LAKPPPQAPPALATPPLQALPSPPASFPGQAP 543



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 5/112 (4%)

Query: 119 PPSPLTPLPPSPTAPRRSQYPSPGSRVGR-GLGTGRGKLAHRVAPSKEPPERACGSRGRS 177
           P  P +P PP P  P   +       VGR  L    G +     P   P      S G S
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86

Query: 178 TGWAASSPKTHAAGQ-APAAARSGRG--AGPAR-EGSGAPSGLGSRAVPVTA 225
           +   AS P     G+ AP A  +  G  + P R  G+  P  LG + + ++A
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 8/110 (7%)

Query: 120 PSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHR---VAPSKEPPERACGSRGR 176
           P  LTP PP    P     P+    +G     GR  LA R   +  +  P         R
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 177 STGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
           S G ++ +P    A + PA+ R G  A PA+  S  P     RA   T P
Sbjct: 82  SAGTSSRNP----ASRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRP 126



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 55/215 (25%), Positives = 79/215 (36%), Gaps = 35/215 (16%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P A   +S    G+  +  +  PP   + +  PPA  + P P          + P  L
Sbjct: 73  SAPRAGPTRSA---GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
             +    S    +   +   +P +S AL     R TS             P TP  PSP 
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRS-ALSAGARRDTS------------GP-TPGTPSPA 175

Query: 132 APRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAG 191
             RRS+  + G+ VG            R APS  P     G R      + SS   H+  
Sbjct: 176 MARRSR--AAGTEVG----------LPRPAPSARPRPPTEGPRK-----SVSSASEHSTT 218

Query: 192 QAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
           +   AAR    AG   +   + S L S A P+++P
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRS-LSSSATPLSSP 252



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 63/235 (26%), Positives = 86/235 (36%), Gaps = 34/235 (14%)

Query: 26  GSGRQTASPSP----------PRCAKTQ--LTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           G+ R T+ P+P           R A T+  L  PA  + P PP E    P+ S       
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG---PRKSVSSASEH 215

Query: 74  EASLTSPLALIPPSEP---QHSPSKSRALCNRGLRSTSRC--TQQGLPSVPPSPLTPLP- 127
             +  SP A   PS     Q   S+S +     L S +R   + +G P  P  P  P P 
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275

Query: 128 -------PSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGW 180
                  P  T PR+   P+ G      L T     A     S+ PP         S   
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAA---LQSQAPPTLPATPHSSSLTC 332

Query: 181 AASSPKTHAAGQAPAAARSGR--GAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
             ++P    A  +P+A  S +   + PA   S A + LGS  +  T   L   PL
Sbjct: 333 QLATP-LPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL 386


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 51.6 bits (122), Expect = 6e-07
 Identities = 74/265 (27%), Positives = 93/265 (35%), Gaps = 50/265 (18%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPS--PPRCAKTQLTPPAIRSCPLPPEEDLLTPQGS--- 66
           S P +  VQ+P F        SPS  PP  A   L  P ++  P PP    ++P  +   
Sbjct: 402 SPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP 460

Query: 67  -------APRLLLGEASLTSPLALIPP------SEPQHSPSKSRALCNRGLRSTSRCTQQ 113
                  AP L L +    +P AL  P      S P   P ++    +  L  +   T  
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520

Query: 114 GLPSVPP---SPLTPLPPSP------TAPRRSQYPSP-----GSRVGRGLGTG------- 152
             P  PP   +PL  +PPSP       APRR   P P     G R+   L  G       
Sbjct: 521 --PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578

Query: 153 -------RGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGP 205
                     LA   + +   PE   G      G AA+SP   A   A   A   RG  P
Sbjct: 579 SPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAP 638

Query: 206 AREGSGAPSGLGSRAVPVTAPRLRD 230
                GAP G      P T P   D
Sbjct: 639 PLAFRGAP-GAPLPWPPATGPGSAD 662



 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 67/233 (28%), Positives = 90/233 (38%), Gaps = 18/233 (7%)

Query: 12  SKPAASGVQSPTFHGSGRQTASP--SPPRCAKTQLTPPAIRSCPLPPEEDLLT----PQG 65
           S PA+   Q+P F  S     SP  +PP  A   L  P ++  P PP    L     P  
Sbjct: 494 SPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 552

Query: 66  SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRA---LCNRGLRSTSRCTQ-QGLPSVPPS 121
             P   +    LT  LA  PP  P  SPS + +   L      +TS   + +G  S P  
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612

Query: 122 PLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSR-GRSTGW 180
                PP P A   + +P+  SR        RG      AP   PP    GS  G  T +
Sbjct: 613 GAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPG---APLPWPPATGPGSADGLCTIY 668

Query: 181 AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
               P++  A  AP A   G   G +   + A +G G+ +      RL + PL
Sbjct: 669 ETEGPES--ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 719



 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 59/212 (27%), Positives = 75/212 (35%), Gaps = 37/212 (17%)

Query: 4   PDLVNQCSSKPAASGVQSPTFHGSGRQTAS----PSPPRCAKTQLTPPAIRSCPLPPEED 59
           P  +    S PA    Q+ T  GS    A+    PSPP        P A  +  LPP + 
Sbjct: 309 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQA 368

Query: 60  LLTPQGSAPRLLLGEASLTSPLALI----------PPSEPQHSPSKSRALCNRGLRSTSR 109
             +P  S P   L   S  +P AL           PPS P  +P    A  +  +  ++ 
Sbjct: 369 PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPA--SPPVSPSAT 426

Query: 110 CTQQGLPS-------VPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP 162
              Q  PS       VPPSP    P SP+A    Q P P              LA     
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP--------------LAAPPLQ 472

Query: 163 SKEPPERACGSRGRSTGWAASSPKTHAAGQAP 194
             +PP +A  +       A  SP     GQAP
Sbjct: 473 LAKPPPQAPPALATPPLQALPSPPASFPGQAP 504



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 52/194 (26%), Positives = 68/194 (35%), Gaps = 38/194 (19%)

Query: 26  GSGRQTASPSP----------PRCAKTQ--LTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           G+ R T+ P+P           R A T+  L  PA  + P PP E    P+ S       
Sbjct: 150 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG---PRKSVSSASEH 206

Query: 74  EASLTSPLALIPPSEP---QHSPSKSRALCNRGLRSTSRC--TQQGLPSVPPSPLTP--- 125
             +  SP A   PS     Q   S+S +     L S +R   + +G P  P  P  P   
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266

Query: 126 -----LPPSPTAPRRSQYPSPGSRVGRGLGT----------GRGKLAHRVAPSKEPPERA 170
                 PP  T PR+   P+ G      L T              L    +P   PP +A
Sbjct: 267 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQA 326

Query: 171 CGSRGRSTGWAASS 184
             S G  T  A  S
Sbjct: 327 TTSLGSPTLQATHS 340



 Score = 32.7 bits (73), Expect = 0.27
 Identities = 32/107 (29%), Positives = 39/107 (36%), Gaps = 11/107 (10%)

Query: 120 PSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTG 179
           P  LTP PP    P     P+    +G     GR  LA          ERA G  G +  
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLA----------ERAGGIGGATIP 71

Query: 180 WAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
            +A         + PA+ R G  A PA+  S  P     RA   T P
Sbjct: 72  ESAPRAGPTRTSRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRP 117



 Score = 31.2 bits (69), Expect = 0.79
 Identities = 28/102 (27%), Positives = 37/102 (36%), Gaps = 7/102 (6%)

Query: 119 PPSPLTPLPPSPTAPRRSQYPSPGSRVGR-GLGTGRGKLAHRVAPSKEP---PERACGSR 174
           P  P +P PP P  P   +       VGR  L    G +     P   P   P R   SR
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT--SR 84

Query: 175 GRSTGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGL 216
             ++G    +P        P ++  GR +G  R G     GL
Sbjct: 85  PPASGRGERAPPAKNTSPGPVSS-PGRASGTTRPGPLGQKGL 125


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 51.2 bits (121), Expect = 7e-07
 Identities = 53/202 (26%), Positives = 70/202 (34%), Gaps = 43/202 (21%)

Query: 29  RQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSE 88
           R++ SP+PP   +   TPP  R  P PP      P+  +P          SP    PP +
Sbjct: 558 RRSPSPAPPPRRRRTPTPPPRRRTPSPP------PRRRSP----------SPRRYSPPIQ 601

Query: 89  PQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRG 148
            ++SPS                        PP   T  PP P   R S  P P  RV   
Sbjct: 602 RRYSPSP-----------------------PPKRRTASPPPPPKRRASPSPPPKRRVSHS 638

Query: 149 LGTGR--GKLAHRVAPSKEPPERACGSRGRSTGWAASSP--KTHAAGQAPAAARSGRGAG 204
               +    +  R +PS     R   S  RST  A S    K H+    P A ++     
Sbjct: 639 PPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPP 698

Query: 205 PAREGSGAPSGLGSRAVPVTAP 226
           P R G+ +         P T P
Sbjct: 699 PVRRGASSSPQRRQSPSPSTRP 720



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 35/139 (25%), Positives = 53/139 (38%), Gaps = 20/139 (14%)

Query: 33  SPSP-PRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQH 91
           SPSP PR  +T  +PP +R               S+P+     +  T P+  +  +    
Sbjct: 683 SPSPRPRAPQTSSSPPPVRR-----------GASSSPQRRQSPSPSTRPIRRVSRTP--- 728

Query: 92  SPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGT 151
            P K +   +   +S  R +     S  P P    PP+P +P +SQ PS        +  
Sbjct: 729 EPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPV-- 786

Query: 152 GRGKLAHRVAPSKEPPERA 170
              K A    PS  PP  +
Sbjct: 787 ---KKAKSPTPSPSPPRNS 802



 Score = 31.6 bits (70), Expect = 0.61
 Identities = 39/146 (26%), Positives = 57/146 (39%), Gaps = 23/146 (15%)

Query: 90  QHSPSKSRALC--NRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGR 147
           +HSPS+S +     R   ++ R  ++  PS PP+     P     PRR + P+P  R   
Sbjct: 522 RHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPR--- 578

Query: 148 GLGTGRGKLAHRVAPSKEPPERACGSRGRS----TGWAASSP--KTHAAGQAPAAARSGR 201
                      R  PS  P  R+   R  S      ++ S P  +  A+   P   R+  
Sbjct: 579 -----------RRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASP 627

Query: 202 GAGPAREGSGAPSGLGSRAVPVTAPR 227
              P R  S +P     R+ PVT  R
Sbjct: 628 SPPPKRRVSHSPPP-KQRSSPVTKRR 652



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 36/131 (27%), Positives = 49/131 (37%), Gaps = 27/131 (20%)

Query: 67  APRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNR-------GLRSTSRCTQQGLP--- 116
           +PR        T P  + PP  P+H  S+S     R       G  S+S  ++   P   
Sbjct: 316 SPRRRPSPRRRTPPRRMPPP--PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKK 373

Query: 117 -----SVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP---SKEPPE 168
                S PP     L PS + PRR   PSP +       T   K  H   P   ++    
Sbjct: 374 PPKRTSSPPRKTRRLSPSASPPRRRHRPSPPA-------TPPPKTRHSPTPQQSNRTRKS 426

Query: 169 RACGSRGRSTG 179
           R   S GR++G
Sbjct: 427 RVSVSPGRTSG 437


>gi|117938768 GNAS complex locus alex [Homo sapiens]
          Length = 626

 Score = 48.5 bits (114), Expect = 5e-06
 Identities = 62/210 (29%), Positives = 81/210 (38%), Gaps = 26/210 (12%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEA-SLTSPLALIPPSEPQHS 92
           P PP+   T   P  +   P+P     LTPQ   P  + G    L  PL L+ P +P  S
Sbjct: 372 PLPPQPIPTPGRP--LTPQPIPTPGRPLTPQ---PIQMPGRPLRLPPPLRLLRPGQPM-S 425

Query: 93  PSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTG 152
           P   +    +GL         G P     PL PLPP P A   S  P+P SR+   L  G
Sbjct: 426 PQLRQT---QGLPLPQPLLPPGQPKSAGRPLQPLPPGPDARSISDPPAPRSRLPIRLLRG 482

Query: 153 RGKLAHRVAPSKEPPERACGSRGRSTGWAAS--SPKTHAAGQAPAAARSGRGAG--PARE 208
              L  R+     P   A  +     GW A+  +P   +    P  A +G   G   A E
Sbjct: 483 ---LLARLPGGASPRAAAAAACTTMKGWPAATMTPAETSPTMGPPDASAGFSIGEIAAAE 539

Query: 209 GSGA---------PSGLGSRAVPVTAPRLR 229
              A         PSG  S  + V +P+ R
Sbjct: 540 SPSATYSATFSCKPSGAASVDLRVPSPKPR 569



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 25/163 (15%)

Query: 4   PDLVNQCSSKPAASGVQSPTFHG-SGRQTASPS---PPRCAKTQLTPPAIRSCPLPPEED 59
           PD  ++ ++ P  S     T+     R TA PS    P+  +++   P +R      +E 
Sbjct: 243 PDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRRKQQRWKEP 302

Query: 60  LLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLP--- 116
           L+ P+      L G    T PL   PP +PQ  P   + L  + + +  +  +   P   
Sbjct: 303 LM-PRREEKYPLRG----TDPL---PPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQH 354

Query: 117 --------SVP-PSPLTPLPPSP-TAPRRSQYPSPGSRVGRGL 149
                   S P P+P  PLPP P   P R   P P    GR L
Sbjct: 355 QPILTPGHSQPIPTPGQPLPPQPIPTPGRPLTPQPIPTPGRPL 397


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
          Length = 1124

 Score = 47.8 bits (112), Expect = 8e-06
 Identities = 67/233 (28%), Positives = 90/233 (38%), Gaps = 18/233 (7%)

Query: 12   SKPAASGVQSPTFHGSGRQTASP--SPPRCAKTQLTPPAIRSCPLPPEEDLLT----PQG 65
            S PA+   Q+P F  S     SP  +PP  A   L  P ++  P PP    L     P  
Sbjct: 802  SPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 860

Query: 66   SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRA---LCNRGLRSTSRCTQ-QGLPSVPPS 121
              P   +    LT  LA  PP  P  SPS + +   L      +TS   + +G  S P  
Sbjct: 861  PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 920

Query: 122  PLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSR-GRSTGW 180
                 PP P A   + +P+  SR        RG      AP   PP    GS  G  T +
Sbjct: 921  GAAASPP-PDAELAACHPAAWSRGPAPPLAFRGAPG---APLPWPPATGPGSADGLCTIY 976

Query: 181  AASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
                P++  A  AP A   G   G +   + A +G G+ +      RL + PL
Sbjct: 977  ETEGPES--ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 1027



 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 65/237 (27%), Positives = 83/237 (35%), Gaps = 33/237 (13%)

Query: 22  PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPL 81
           P+   S   + S +PP      L  P ++  P PP    ++P    P      A  T PL
Sbjct: 739 PSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQA-PPALATPPL 797

Query: 82  ALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPP---SPLTPLPPSP------TA 132
             +P S P   P ++    +  L  +   T    P  PP   +PL  +PPSP       A
Sbjct: 798 QALP-SPPASFPGQAPFSPSASLPMSPLATPP--PQAPPVLAAPLLQVPPSPPASPTLQA 854

Query: 133 PRRSQYPSP-----GSRVGRGLGTG--------------RGKLAHRVAPSKEPPERACGS 173
           PRR   P P     G R+   L  G                 LA   + +   PE   G 
Sbjct: 855 PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGY 914

Query: 174 RGRSTGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRD 230
                G AA+SP   A   A   A   RG  P     GAP G      P T P   D
Sbjct: 915 DSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP-GAPLPWPPATGPGSAD 970



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 46/157 (29%), Positives = 58/157 (36%), Gaps = 52/157 (33%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPR------CAKTQLTPP------------------ 47
           S PA SG   P+  G+ R  A PS P+          Q+TPP                  
Sbjct: 250 SSPARSG---PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306

Query: 48  ----AIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRG 103
                 ++ P+PP ++  TP    P  L     L +PL L PPS P   PS         
Sbjct: 307 PSPSGTKARPVPPPDNAATP---LPATLPPSPPLATPLPLAPPS-PSAPPSL-------- 354

Query: 104 LRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPS 140
                    Q LPS P +P +  PPS T P     PS
Sbjct: 355 ---------QTLPSPPATPPSQAPPSMTTPPMQAPPS 382



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 45/153 (29%), Positives = 62/153 (40%), Gaps = 19/153 (12%)

Query: 4   PDLVNQCSSKP--AASGVQSPTFHGSGRQTASP--SPPRCAKTQLTPPAIRSCPLPPEED 59
           P+  +  ++ P  A   + SP   G      SP  +PP  A   L  P +++ P PP   
Sbjct: 581 PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASP 640

Query: 60  ----LLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGL 115
               L TP   AP  L     L +P +  PPS P  +P    A  +  +  ++    Q  
Sbjct: 641 PLSPLATPSPQAPNALAVHL-LQAPFSP-PPSPPVQAPFSPPA--SPPVSPSATPPSQAP 696

Query: 116 PS-------VPPSPLTPLPPSPTAPRRSQYPSP 141
           PS       VPPSP    P SP+A    Q P P
Sbjct: 697 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729



 Score = 38.5 bits (88), Expect = 0.005
 Identities = 47/169 (27%), Positives = 65/169 (38%), Gaps = 18/169 (10%)

Query: 14  PAASGVQSPTFHGSGRQTASPS----PPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPR 69
           PA   +Q+P    +     +PS    PP  A   L  P ++  P PP   L TP   AP 
Sbjct: 564 PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAP- 622

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCN-RGLRSTSRCTQQGLPSVPPSPLTPLPP 128
                  L  P    PPS P   P    A  + +   + +    Q   S PPSP    P 
Sbjct: 623 -----PXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 677

Query: 129 SPTA-PRRSQYPSPGSRVGRGLGTGRGKL------AHRVAPSKEPPERA 170
           SP A P  S   +P S+    L     ++      +  ++PS  PP +A
Sbjct: 678 SPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 32/112 (28%), Positives = 44/112 (39%), Gaps = 5/112 (4%)

Query: 119 PPSPLTPLPPSPTAPRRSQYPSPGSRVGR-GLGTGRGKLAHRVAPSKEPPERACGSRGRS 177
           P  P +P PP P  P   +       VGR  L    G +     P   P      S G S
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTS 86

Query: 178 TGWAASSPKTHAAGQ-APAAARSGRG--AGPAR-EGSGAPSGLGSRAVPVTA 225
           +   AS P     G+ AP A  +  G  + P R  G+  P  LG + + ++A
Sbjct: 87  SRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISA 138



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 54/217 (24%), Positives = 70/217 (32%), Gaps = 39/217 (17%)

Query: 33  SPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHS 92
           +P P + A   LT P + + P P    L  P           + LT+P    P S     
Sbjct: 542 APPPLQTASAPLTTPHLETPPCPAPCPLQAP----------PSPLTTPPPETPSSIATPP 591

Query: 93  PSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPS----------------PTAPRRS 136
           P    AL +  L        QGLPS P SPL   PP                 P +P  S
Sbjct: 592 PQAPPALASPPL--------QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLS 643

Query: 137 QYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAA 196
              +P  +    L      L    +P   PP +A  S   S      SP      QAP +
Sbjct: 644 PLATPSPQAPNALAV--HLLQAPFSPPPSPPVQAPFSPPAS---PPVSPSATPPSQAPPS 698

Query: 197 ARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFPL 233
             +     P    +  P    +   P   P L   PL
Sbjct: 699 LAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 735



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 33/110 (30%), Positives = 43/110 (39%), Gaps = 8/110 (7%)

Query: 120 PSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHR---VAPSKEPPERACGSRGR 176
           P  LTP PP    P     P+    +G     GR  LA R   +  +  P         R
Sbjct: 22  PGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTR 81

Query: 177 STGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
           S G ++ +P    A + PA+ R G  A PA+  S  P     RA   T P
Sbjct: 82  SAGTSSRNP----ASRPPASGR-GERAPPAKNTSPGPVSSPGRASGTTRP 126



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 55/215 (25%), Positives = 79/215 (36%), Gaps = 35/215 (16%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P A   +S    G+  +  +  PP   + +  PPA  + P P          + P  L
Sbjct: 73  SAPRAGPTRSA---GTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL 129

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
             +    S    +   +   +P +S AL     R TS             P TP  PSP 
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRS-ALSAGARRDTS------------GP-TPGTPSPA 175

Query: 132 APRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAG 191
             RRS+  + G+ VG            R APS  P     G R      + SS   H+  
Sbjct: 176 MARRSR--AAGTEVG----------LPRPAPSARPRPPTEGPRK-----SVSSASEHSTT 218

Query: 192 QAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
           +   AAR    AG   +   + S L S A P+++P
Sbjct: 219 EPSPAARRRPSAGGGLQRPASRS-LSSSATPLSSP 252



 Score = 32.3 bits (72), Expect = 0.36
 Identities = 59/228 (25%), Positives = 81/228 (35%), Gaps = 33/228 (14%)

Query: 26  GSGRQTASPSP----------PRCAKTQ--LTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           G+ R T+ P+P           R A T+  L  PA  + P PP E    P+ S       
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG---PRKSVSSASEH 215

Query: 74  EASLTSPLALIPPSEP---QHSPSKSRALCNRGLRSTSRC--TQQGLPSVPPSPLTPLP- 127
             +  SP A   PS     Q   S+S +     L S +R   + +G P  P  P  P P 
Sbjct: 216 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 275

Query: 128 -------PSPTAPRRSQYPSPGSRVGRGLGT--GRGKLAHRVAPSKEPPERACGSRGRST 178
                  P  T PR+   P+ G      L T    G  A  V P          +   S 
Sbjct: 276 GLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSP 335

Query: 179 GWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
             A   P    +  AP + ++   + PA   S AP  +     P+ AP
Sbjct: 336 PLATPLPLAPPSPSAPPSLQT-LPSPPATPPSQAPPSM--TTPPMQAP 380



 Score = 28.5 bits (62), Expect = 5.2
 Identities = 44/158 (27%), Positives = 59/158 (37%), Gaps = 30/158 (18%)

Query: 11  SSKPAASGVQSPTFHG-------SGRQTASP--SPPRCAKTQLTPPAIRSCPL-----PP 56
           SS  A + + SPT          S RQT +   SP R A T    P +++ PL     PP
Sbjct: 410 SSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQA-PLSLPASPP 468

Query: 57  EEDLLTPQGSA--------PRLLLGEASLTSPLA-----LIPPSEPQHSPSKSRALCNRG 103
            +  L+P  S         P   L   +  SP A     ++PP E Q S +         
Sbjct: 469 LQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPA 528

Query: 104 LRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP 141
             +T     + LPS+ P PL       T P     P P
Sbjct: 529 SLTTPPL--ENLPSLAPPPLQTASAPLTTPHLETPPCP 564


>gi|145386517 phostensin [Homo sapiens]
          Length = 613

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 19/129 (14%)

Query: 30  QTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEP 89
           QT  P PP  A+  L  P + +     E++    QG   R L    S+ SPL   PP + 
Sbjct: 352 QTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPL---PPEDA 408

Query: 90  QHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP-----GSR 144
                        GLR       +  P  PP+PL+P PP+PTAP+    P       G +
Sbjct: 409 GTG----------GLRQQEEEAVELQPP-PPAPLSPPPPAPTAPQPPGDPLMSRLFYGVK 457

Query: 145 VGRGLGTGR 153
            G G+G  R
Sbjct: 458 AGPGVGAPR 466


>gi|199559805 phostensin [Homo sapiens]
          Length = 613

 Score = 47.4 bits (111), Expect = 1e-05
 Identities = 40/129 (31%), Positives = 54/129 (41%), Gaps = 19/129 (14%)

Query: 30  QTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEP 89
           QT  P PP  A+  L  P + +     E++    QG   R L    S+ SPL   PP + 
Sbjct: 352 QTQKPEPPESAEKLLESPGVEAGEGEAEKEEAGAQGRPLRALQNCCSVPSPL---PPEDA 408

Query: 90  QHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP-----GSR 144
                        GLR       +  P  PP+PL+P PP+PTAP+    P       G +
Sbjct: 409 GTG----------GLRQQEEEAVELQPP-PPAPLSPPPPAPTAPQPPGDPLMSRLFYGVK 457

Query: 145 VGRGLGTGR 153
            G G+G  R
Sbjct: 458 AGPGVGAPR 466


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 47.0 bits (110), Expect = 1e-05
 Identities = 56/217 (25%), Positives = 78/217 (35%), Gaps = 31/217 (14%)

Query: 32   ASPSPPRCAKTQL-TPPAIRSCPL-PPEEDLLTPQGSAPRLLLG------EASLTSPLAL 83
            A+PSP     T   TPP+ +  P  PP +   TP  + P  L G           +P  +
Sbjct: 1233 ATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV 1292

Query: 84   IPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYP---- 139
             PPS P+  P+ S         + +  + +G P  PP    P PP+ T P     P    
Sbjct: 1293 TPPS-PKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPA 1351

Query: 140  -SPGSRVG-------RGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAG 191
             +P S+ G        G        +H+  P+  PP           G A  SPK     
Sbjct: 1352 TTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP-------SPKRGPAIPSPKGDPTS 1404

Query: 192  QA--PAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
             A  P + +        REG+  PS  G    P   P
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPS-KGDLTPPAVTP 1440



 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 61/223 (27%), Positives = 87/223 (39%), Gaps = 28/223 (12%)

Query: 28   GRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPS 87
            G  T   + P   K     P+ +  P PP     +P+GS       + + T P A  PPS
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPP-AATPPS 1042

Query: 88   EPQHSPSKSRALCNRGLRSTSRCT---QQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSR 144
             P+ SP+ +     +G  +T   T    +G P+ P     P PP+ T P     P+  S 
Sbjct: 1043 -PKGSPAATP--LPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSP 1099

Query: 145  VGRGL------GTGRGKLA---HRVA---PSKEPPERACG-----SRGRSTGWAAS--SP 185
             G  +       + +G LA   H+ A   P+  PP    G      +G  T  AA+  SP
Sbjct: 1100 KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSP 1159

Query: 186  KTHAAGQAPAAARSGRGAGP--AREGSGAPSGLGSRAVPVTAP 226
            K   A   P  A +   A P   + G   PS  G+   P   P
Sbjct: 1160 KGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1202



 Score = 42.7 bits (99), Expect = 3e-04
 Identities = 68/236 (28%), Positives = 94/236 (39%), Gaps = 40/236 (16%)

Query: 11   SSKPAASGVQSPTFHGSGRQTASP--SPPRCAKTQLTP------PAIRSCPLPPEEDLLT 62
            S+ PAA+    P+  GS   T  P  +P   A T  +P      P+++  P PP     +
Sbjct: 1033 STPPAAT---PPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089

Query: 63   PQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRAL-CNRGLRSTSRCTQQGLPSVPPS 121
            P+G       G A+ +   A +PP+    SP    A   ++G  +T   T    P  P  
Sbjct: 1090 PKG-------GPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAAT----PPSPKG 1138

Query: 122  PLTPLPP--SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACG-----SR 174
             L   PP  +PT P  +  PSP      GL T   K A    P+  PP    G      +
Sbjct: 1139 GLATPPPKGAPTTPAATP-PSPKG----GLATPPPKGA-PTTPAATPPSPKGGLATPSPK 1192

Query: 175  GRSTGWAAS--SPKTHAAGQAPAAARSGRGAGP--AREGSGAPSGLGSRAVPVTAP 226
            G  T  AA+  SPK   A  +P  A +   A P   + G   PS  G+   P   P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATP 1248



 Score = 39.7 bits (91), Expect = 0.002
 Identities = 52/217 (23%), Positives = 75/217 (34%), Gaps = 24/217 (11%)

Query: 30   QTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEP 89
            QT  P   + +    TP    S P+ P E    P+ S    L  + S  SP     P+ P
Sbjct: 804  QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENS----LSFQGSKDSPATTHSPTPP 859

Query: 90   QH----SPSKSRALCNRGL----RSTSRCTQQGLPSVPPSPLTPLP---PSPTAPRRSQY 138
                  +PS    L  +G+    + T   +   LP     P TP P   P+ +    S  
Sbjct: 860  SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPK 919

Query: 139  PSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAAS-------SPKTHAAG 191
             +  +   +G+            P+  PP    G    S  WA +       SPK   A 
Sbjct: 920  KARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPAT 979

Query: 192  QAPAAARSGRGAGP--AREGSGAPSGLGSRAVPVTAP 226
             +P  A +   A P   + G   PS  G+   P   P
Sbjct: 980  PSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP 1016



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 55/237 (23%), Positives = 79/237 (33%), Gaps = 29/237 (12%)

Query: 4    PDLVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTP 63
            P  V   SS   A    +P     G  T     P   K     P+ R  P+ P   LL+ 
Sbjct: 1481 PKQVATSSSPKKAPATPAPM----GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSK 1536

Query: 64   QGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPL 123
            +  A        +L    ALIPP+    SP K+ A+           T +  P+ P S  
Sbjct: 1537 KTPA--------TLAPKEALIPPAMTVPSPKKTPAI----------PTPKEAPATPSSKE 1578

Query: 124  TPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACG-----SRGRST 178
               PP+ T       PSP   +     T          P+  PP    G      +G  T
Sbjct: 1579 ASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPT 1638

Query: 179  GWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVP--VTAPRLRDFPL 233
                +      +  +PA+     GA   +   G P+  G  A+   + AP     P+
Sbjct: 1639 SPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPI 1695



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 38/132 (28%), Positives = 56/132 (42%), Gaps = 13/132 (9%)

Query: 19   VQSPTFHG-SGRQTASPSPPRC----AKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
            + +PT  G   +++++ SPP C    AK     P     P P    LL  Q  + +   G
Sbjct: 1696 ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAP----LLPVQKDSSKTAKG 1751

Query: 74   EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPS-PLTPLPPSPTA 132
            + +  SP   + P E + S   + A   + L      +    PS P S PL P  P PT 
Sbjct: 1752 KDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAP-SPVPTL 1810

Query: 133  PRRSQY--PSPG 142
            P + Q+   SPG
Sbjct: 1811 PPKQQFLPSSPG 1822



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 34/136 (25%), Positives = 49/136 (36%), Gaps = 23/136 (16%)

Query: 11   SSKPAASGVQSPTFHGSGRQTASPSPPR-----CAKTQLTPPAIRSCPLPPEEDLLTPQG 65
            SSK   +   +   H  G     PSP R       K   T PA+   PL P++   TP  
Sbjct: 1364 SSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAV--IPLSPKKAPATPVT 1421

Query: 66   SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTP 125
                    +  LT P   + P   + +P+ S                +G P+ P S   P
Sbjct: 1422 REGAATPSKGDLTPPA--VTPVSLKKAPATS--------------APKGGPATPSSKGDP 1465

Query: 126  LPPSPTAPRRSQYPSP 141
              P+ T P   + P+P
Sbjct: 1466 TLPAVTPPSPKEPPAP 1481


>gi|4504733 insulin receptor substrate 4 [Homo sapiens]
          Length = 1257

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 13/153 (8%)

Query: 73  GEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTA 132
           GE  +      + PSEP     + R    RG RS          SVP S    L PSP  
Sbjct: 389 GEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAV------SVPASFFRRLAPSPAR 442

Query: 133 PRR-SQYPSPGSRVGRGL-GTGRGKLAHRVAP-SKEPPERACGSRGRSTGWAASSPKTHA 189
           PR  ++ P+ G+R+   + G+G G       P  KE  E + G       W + + +   
Sbjct: 443 PRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSG 502

Query: 190 AGQAP----AAARSGRGAGPAREGSGAPSGLGS 218
            GQ      +++ S  G   + EG G+  G GS
Sbjct: 503 GGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGS 535


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 46.6 bits (109), Expect = 2e-05
 Identities = 60/204 (29%), Positives = 77/204 (37%), Gaps = 33/204 (16%)

Query: 29   RQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSE 88
            R  +  SP   +K++L+P   RS   P  +D      +APR   G  S   P A  P + 
Sbjct: 1576 RSRSGSSPEVDSKSRLSPRRSRSGSSPEVKD---KPRAAPRAQSGSDSSPEPKAPAPRAL 1632

Query: 89   PQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLT----------PLPPSPTAPRR-SQ 137
            P+ S S S +   RG       + +  P  PP   T          P   S T PRR S 
Sbjct: 1633 PRRSRSGSSSK-GRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSS 1691

Query: 138  YPSPG-------SRVGRGLGTG-----RGKLAHRVAPSKEPPERACGSRGRSTGWAASSP 185
              SP        SR  R   +      R    HR +PS   PE A  SR      +ASSP
Sbjct: 1692 RSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSP 1751

Query: 186  KTHAAGQAPAAARSGRGAGPAREG 209
            +T         +R GR   P   G
Sbjct: 1752 RT------KTTSRRGRSPSPKPRG 1769



 Score = 42.0 bits (97), Expect = 5e-04
 Identities = 63/220 (28%), Positives = 87/220 (39%), Gaps = 20/220 (9%)

Query: 12   SKPAASGVQSPTFHGSG---RQTASPSPPRCAKTQLTPPAIRS-CPLPPEEDLLTPQGSA 67
            S+ + SG       GSG   R + S S P       TP   RS C   PE   L PQ   
Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKAL-PQTPR 1494

Query: 68   PRLLLGEASLTSPLALIPPSEPQHSPS----KSRALCNRGLRSTSRCTQQ--GLPSVPPS 121
            PR     +   +   L P  E   S S    K+ A    G RS S  +Q+    PS  P 
Sbjct: 1495 PRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQ 1554

Query: 122  PLTPLPPSPTAPRRSQYP-SPGSRVGRGLGT-GRGKLAHRVAPSKEPPE----RACGSRG 175
              +    SP +  +++ P    SR G       + +L+ R + S   PE         R 
Sbjct: 1555 ERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRA 1614

Query: 176  RSTGWAASSPKTHAAGQAPAAARSG---RGAGPAREGSGA 212
            +S   ++  PK  A    P  +RSG   +G GP+ EGS +
Sbjct: 1615 QSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSS 1654



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 35/117 (29%), Positives = 45/117 (38%), Gaps = 6/117 (5%)

Query: 11   SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRL 70
            SS  ++S   S +   S   ++SPSP +     L  PA    P P E    +P+     L
Sbjct: 2626 SSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSL 2685

Query: 71   LLGEASLTSPLALIPPSEPQHSP-----SKSRALCNRGLRSTSRCTQQGLPSVPPSP 122
                +   SP+    PS PQ SP     S S     RG R  SR          PSP
Sbjct: 2686 RDSRSLSYSPVERRRPS-PQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSP 2741



 Score = 35.4 bits (80), Expect = 0.042
 Identities = 45/198 (22%), Positives = 70/198 (35%), Gaps = 13/198 (6%)

Query: 29  RQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSE 88
           R  +  SP    K+Q  P   RS    P+    TP    PR     +S         PS 
Sbjct: 777 RSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP----PRRSRSSSSPPPKQKSKTPSR 832

Query: 89  PQHSPSKSRALCNRGL---RSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRV 145
             HS S        G    + +    Q    SV P   +    SP    +S+ PS  S  
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892

Query: 146 GRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGP 205
           G      +        P ++ P R+   + +     +   ++H+   +P+ +R      P
Sbjct: 893 GSSPPRVKSS-----TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTP 947

Query: 206 AREGSGAP-SGLGSRAVP 222
            R  S +P S + SR +P
Sbjct: 948 RRSRSVSPCSNVESRLLP 965



 Score = 35.0 bits (79), Expect = 0.055
 Identities = 62/272 (22%), Positives = 92/272 (33%), Gaps = 66/272 (24%)

Query: 13  KPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPL------PPEEDLLTPQGS 66
           K A     SP    +G +  +P+P    +   +P  + + PL      PP E   T   S
Sbjct: 345 KSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404

Query: 67  APRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPL 126
            P+         SP  L   S  + SP   +    +  R  S   +   P+  P     +
Sbjct: 405 PPK---------SPEKLPQSSSSESSPPSPQP--TKVSRHASSSPESPKPAPAPGSHREI 453

Query: 127 PPSPTAPRRSQ---------YPSPGSRVGRGLGTG------------------------- 152
             SPT+  RS            +P  R+GR                              
Sbjct: 454 SSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQW 513

Query: 153 -RGKLAHRVAPSKEP--------PERACGSRGRST---GWAASSPKTHAAGQAPAAARSG 200
            R + A R   S+ P        P+R   SR R+T   G + S+ +  +  ++PA     
Sbjct: 514 RRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS 573

Query: 201 RGAGPAREG---SGAPSGLGSRAVPVTAPRLR 229
           R   PAR G   S  P+   SR+   T  R R
Sbjct: 574 RSRTPARRGRSRSRTPARRRSRSRTPTRRRSR 605



 Score = 34.7 bits (78), Expect = 0.072
 Identities = 59/234 (25%), Positives = 87/234 (37%), Gaps = 40/234 (17%)

Query: 17   SGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQ-----------G 65
            +G ++P    +   T S +PP  A     P + R+   P   +L+ P+           G
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTAANY---PSSSRTPQAPASANLVGPRSAHATAPVNIAG 2354

Query: 66   SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTP 125
            S     L  ASLTS  A + P+    + +  R   +   R + R T   L     S   P
Sbjct: 2355 SRTAAALAPASLTS--ARMAPALSGANLTSPRVPLSAYERVSGR-TSPPLLDRARSRTPP 2411

Query: 126  LPPSPTAPRRSQYPSPGSRVG----RGLGTGRGKLAHRVAPSKEPPERAC---------G 172
              PS +     + PSP SR+G    + L            PS    +  C         G
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 173  SRGRSTGWAASSPKTHAAGQ--------APAAARSGRGAGPAREGSGAPSGLGS 218
            S+  S+G  A++  T +AG         AP    S  G  PA  G+  PS L +
Sbjct: 2472 SQSLSSGAVATT--TSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 49/218 (22%), Positives = 76/218 (34%), Gaps = 20/218 (9%)

Query: 15  AASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGE 74
           AA G+      GS     S  P R A+    P      P PP+   L  + S+ R    +
Sbjct: 137 AAFGISDSYVDGS-----SFDPQRRAREAKQP-----APEPPKPYSLVRESSSSRSPTPK 186

Query: 75  ASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPR 134
                            SP + R   ++  +  S    +      P+P +         +
Sbjct: 187 QKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRK 246

Query: 135 RSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAP 194
           RS+  +P  +  R         AHR + S +    +  SR RS   AA +  T  AG++P
Sbjct: 247 RSRSTTPAPKSRR---------AHR-STSADSASSSDTSRSRSRSAAAKTHTTALAGRSP 296

Query: 195 AAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFP 232
           + A   RG G A       +     + P TA +    P
Sbjct: 297 SPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSP 334



 Score = 33.5 bits (75), Expect = 0.16
 Identities = 52/218 (23%), Positives = 77/218 (35%), Gaps = 26/218 (11%)

Query: 11   SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPE--EDLLTPQGSAP 68
            SS  ++SG  S    GS    + P  P  A  ++  P     P P E   +   P+ +  
Sbjct: 2550 SSSSSSSGSSSSDSEGS----SLPVQPEVALKRVPSPT----PAPKEAVREGRPPEPTPA 2601

Query: 69   RLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPP 128
            +     +S +S  +    S    S S S +  +    S+S  +     S  PSP  P P 
Sbjct: 2602 KRKRRSSSSSSSSS----SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQ 2657

Query: 129  SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTH 188
            +   P   + P PG R  R        L    + S  P ER   S          SP+  
Sbjct: 2658 ALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPS-------PQPSPRDQ 2710

Query: 189  AAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAP 226
             +  +   +R G+     R  S +PS    R  P   P
Sbjct: 2711 QSSSSERGSRRGQ-----RGDSRSPSHKRRRETPSPRP 2743



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 42/194 (21%), Positives = 71/194 (36%), Gaps = 44/194 (22%)

Query: 51   SCPLP--PEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTS 108
            S P P  P  D+  P  S        A   S LA + P++ + S S S +  +    S+S
Sbjct: 2495 SVPAPGVPHSDVGEPPASTG------AQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS 2548

Query: 109  RCTQQGLP----------SVPPSPLTPLP--PSPT-----APRRSQYPSPGSRVGRGLGT 151
              +               S+P  P   L   PSPT     A R  + P P          
Sbjct: 2549 SSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEP---------- 2598

Query: 152  GRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGPAREGSG 211
                      P+K     +  S   S+  ++SS  + ++  + +++ S   +  +   S 
Sbjct: 2599 ---------TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649

Query: 212  APSGLGSRAVPVTA 225
            +P+  G +A+P  A
Sbjct: 2650 SPAKPGPQALPKPA 2663


>gi|223633935 hypothetical protein LOC254427 [Homo sapiens]
          Length = 435

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 56/209 (26%), Positives = 75/209 (35%), Gaps = 26/209 (12%)

Query: 30  QTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSA--PRLLLGEASLTSPLAL---- 83
           +T  P  P   +T L PP + S P PP  +L  P      PRLL    S+ +PL +    
Sbjct: 145 ETPPPPDPPAPETLLAPPPLPSTPDPPRRELRAPSPPVEHPRLL---RSVPTPLVMAQKI 201

Query: 84  ---------IPPSEP--QHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTA 132
                    + P+ P  +  P + R    RG RS         PS P  P  P  PS   
Sbjct: 202 SERMAGNEALSPTSPFREGRPGEWRTPAARGPRSGDPGPG---PSHPAQPKAPRFPSNII 258

Query: 133 PRRSQYPSPGSRVGRGLGTGRGKLAHRVAP--SKEPPERACGSRGRSTGWAASSPKTHAA 190
                   P   + R   + + + A  +A          A G  G       SSP+  A 
Sbjct: 259 VTNGAAREPRRTLSRAAVSVQERRAQVLATIHGHAGAFPAAGDAGEGAPGGGSSPERVAR 318

Query: 191 GQA-PAAARSGRGAGPAREGSGAPSGLGS 218
           G+  P  A S R  G A  G    +G  S
Sbjct: 319 GRGLPGPAESLRAGGQAPRGPALANGFPS 347


>gi|46852161 methyl-CpG binding domain protein 6 [Homo sapiens]
          Length = 1003

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 66/232 (28%), Positives = 84/232 (36%), Gaps = 41/232 (17%)

Query: 21  SPTFHGSGRQTASPSPPRCAKTQLTPPA-IRSCPLPPEEDLLTPQGSAPRLLLGEASLTS 79
           +PT  G G      +PP  A + L+  A  +  PLPP   L   QG  PR     AS +S
Sbjct: 307 APTVEGPG------APPFLASSLLSAAAKAQHPPLPPPSTL---QGRRPRAQAPSASHSS 357

Query: 80  PLALIPPSE--PQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQ 137
            L    PS+  P+  P+  R L  RG ++  R   +    VP     P P  P  P    
Sbjct: 358 SLR---PSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQPFSLPEPSQPILPSVLS 414

Query: 138 ---YPSPGSRVGRGLGTGRGKLAHRVAP----SKEPPE-------RACGSRGRSTGWAAS 183
               P+PG     G     G  AH   P    S  PP+          G+   S      
Sbjct: 415 LLGLPTPGPSHSDGSFNLLGSDAHLPPPPTLSSGSPPQPRHPIQPSLPGTTSGSLSSVPG 474

Query: 184 SPKTHAAGQAPAAARS---------GRGAGPAREGSGAPSGLGSRAVPVTAP 226
           +P   AA +AP              G GAGPA      P   G  A P  +P
Sbjct: 475 APAPPAASKAPVVPSPVLQSPSEGLGMGAGPA---CPLPPLAGGEAFPFPSP 523



 Score = 37.4 bits (85), Expect = 0.011
 Identities = 45/161 (27%), Positives = 60/161 (37%), Gaps = 24/161 (14%)

Query: 22  PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPL 81
           P  H S    + P    C+   LTPP     PLPP  +L    G A +  +  A++  PL
Sbjct: 246 PAPHASSSPPSDPPLFHCSDA-LTPP-----PLPPSNNLPAHPGPASQPPVSSATMHLPL 299

Query: 82  ALIP--PSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAP------ 133
            L P   +     P     L +  L + ++     LP  PPS L    P   AP      
Sbjct: 300 VLGPLGGAPTVEGPGAPPFLASSLLSAAAKAQHPPLP--PPSTLQGRRPRAQAPSASHSS 357

Query: 134 ------RRSQYPSPGSRV--GRGLGTGRGKLAHRVAPSKEP 166
                 RR + P    R+  GRG  T R       AP  +P
Sbjct: 358 SLRPSQRRPRRPPTVFRLLEGRGPQTPRRSRPRAPAPVPQP 398



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 61/230 (26%), Positives = 74/230 (32%), Gaps = 36/230 (15%)

Query: 10  CSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPR 69
           CS      G     FH     T SP PP        PP   + PL      L P+   P 
Sbjct: 121 CSHSSPGEGASPQMFH-----TVSPGPPSARPPCRVPP---TTPLNGGPGSLPPE--PPS 170

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPP- 128
           +     +L  P  L PP      PS        G  S+ R   +G     PSP  P PP 
Sbjct: 171 VSQAFPTLAGPGGLFPPRLADPVPS--------GGSSSPRFLPRGNA---PSPAPPPPPA 219

Query: 129 -SPTAPRRSQYPS-PGSRVGRGLGTGRGKLAHRVAPSKEP-----------PERACGSRG 175
            S  AP  +   +   S V   LG+     A    PS  P           P     +  
Sbjct: 220 ISLNAPSYNWGAALRSSLVPSDLGSPPAPHASSSPPSDPPLFHCSDALTPPPLPPSNNLP 279

Query: 176 RSTGWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTA 225
              G A+  P + A    P       G  P  EG GAP  L S  +   A
Sbjct: 280 AHPGPASQPPVSSATMHLPLVL-GPLGGAPTVEGPGAPPFLASSLLSAAA 328



 Score = 32.7 bits (73), Expect = 0.27
 Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 65/212 (30%)

Query: 33  SPSPPRCAKTQLTP-PAIRS------------CPLPP------------EEDLLTPQGSA 67
           +P+PP  +K  + P P ++S            CPLPP            E+ L       
Sbjct: 475 APAPPAASKAPVVPSPVLQSPSEGLGMGAGPACPLPPLAGGEAFPFPSPEQGLALSGAGF 534

Query: 68  PRLLLGEASLTSPLAL-IPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPL 126
           P +L    +L  PL+L  PP  P  + S    L   G          G P  PP PL P 
Sbjct: 535 PGML---GALPLPLSLGQPPPSPLLNHSLFGVLTGGG----------GQP--PPEPLLPP 579

Query: 127 PPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPK 186
           P  P  P      +PG   G  L      L   + P   PP              ++ P 
Sbjct: 580 PGGPGPPL-----APGEPEGPSL------LVASLLP--PPPSDLLPP-------PSAPPS 619

Query: 187 THAAGQAPAAA---RSGRGAGPAREGSGAPSG 215
              A   P  A    +G G G A EG+G PSG
Sbjct: 620 NLLASFLPLLALGPTAGDGEGSA-EGAGGPSG 650



 Score = 28.1 bits (61), Expect = 6.7
 Identities = 46/183 (25%), Positives = 58/183 (31%), Gaps = 25/183 (13%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSP 93
           P P R   + L PP     P PP  +LLT +GS  R   G   L        P+  +   
Sbjct: 824 PEPARPPLSALAPP--HGSPDPPVPELLTGRGSGKRGRRGGGGLRGINGEARPARGRKPG 881

Query: 94  SK-----------SRALCNRGLRSTSRCTQ--QGLPSVPPSPLTPLPPSPTAPRRSQYPS 140
           S+           +R   N  +  + R T   Q    +      P  P P  P       
Sbjct: 882 SRREPGRLALKWGTRGGFNGQMERSPRRTHHWQHNGELAEGGAEPKDPPPPGPHSEDLKV 941

Query: 141 PGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSG 200
           P   V +     R K          P   +  SR   T     SP   AA   P  AR G
Sbjct: 942 PPGVVRKSRRGRRRKY--------NPTRNSNSSRQDIT--LEPSPTARAAVPLPPRARPG 991

Query: 201 RGA 203
           R A
Sbjct: 992 RPA 994


>gi|154146199 sal-like 3 [Homo sapiens]
          Length = 1300

 Score = 45.4 bits (106), Expect = 4e-05
 Identities = 43/133 (32%), Positives = 58/133 (43%), Gaps = 18/133 (13%)

Query: 115 LPSVPPSPLTPLPP----------SPTAP---RRSQYPSPGSRVGRGLGTGRGKLAHRVA 161
           LP+VP S    LPP          SP+A    R  Q PSP S     L  G   +   V+
Sbjct: 519 LPTVPTSVGLQLPPTVPGAHGYADSPSATPASRSPQRPSPASSECASLSPGLNHVESGVS 578

Query: 162 PSKEPPERACGSRGRSTGWAASSPKTHA-AGQAPAAARSGRGAGPAREGSGAPSGLGSRA 220
            + E P+   G    +     S P T+A AG AP  A++   A P     GAP+ LGS  
Sbjct: 579 ATAESPQSLLGGPPLTKAEPVSLPCTNARAGDAPVGAQA--SAAPT-SVDGAPTSLGSPG 635

Query: 221 VPVTAPRLR-DFP 232
           +P  + + +  FP
Sbjct: 636 LPAVSEQFKAQFP 648



 Score = 30.0 bits (66), Expect = 1.8
 Identities = 40/154 (25%), Positives = 55/154 (35%), Gaps = 27/154 (17%)

Query: 6   LVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQG 65
           L+ Q  S+ A   +Q P    S    A+PS P  A +QL  P + + PL          G
Sbjct: 222 LIEQIRSQVAL--MQRPPPRPSLSPAAAPSAPGPAPSQL--PGLAALPLSAGAPAAAIAG 277

Query: 66  SAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTP 125
           S P      A+      L  P     +P              +  +    PS  P+P  P
Sbjct: 278 SGPA---APAAFEGAQPLSRPESGASTPG-----------GPAEPSAPAAPSAAPAPAAP 323

Query: 126 LP-PSPTAPRRSQYPS--------PGSRVGRGLG 150
            P P+P +   SQ  S        PGS +G   G
Sbjct: 324 APAPAPQSAASSQPQSASTPPALAPGSLLGAAPG 357



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 53/206 (25%), Positives = 75/206 (36%), Gaps = 39/206 (18%)

Query: 54  LPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQ-HSPSKSRALCNRGLRSTSRCT- 111
           L  +E+LL P G+      GE +  +       S P+  S  +  ++C +      +   
Sbjct: 12  LKSDEELLPPDGAPEHAAPGEGAEDAD------SGPESRSGGEETSVCEKCCAEFFKWAD 65

Query: 112 ----QQGLPSVPPSPLT----PLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKL-----AH 158
               Q+    +PP  +     P PP    P  S   SP  R         G       A 
Sbjct: 66  FLEHQRSCTKLPPVLIVHEDAPAPPPEDFPEPSPASSPSERAESEAAEEAGAEGAEGEAR 125

Query: 159 RVAPSKEP--PERACGSRGRSTGWAASSPKTHAAGQAP--------------AAARSGRG 202
            V    EP   E A  +R      AA +P T A G AP              A A+  +G
Sbjct: 126 PVEKEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYG-APSTNVTLEALLSTKVAVAQFSQG 184

Query: 203 AGPAREGSGAPSGLGSRAVPVTAPRL 228
           A  A  GSGA  G+ + AVP+   +L
Sbjct: 185 ARAAG-GSGAGGGVAAAAVPLILEQL 209



 Score = 28.5 bits (62), Expect = 5.2
 Identities = 23/69 (33%), Positives = 30/69 (43%), Gaps = 7/69 (10%)

Query: 17  SGVQSPTFHGSGRQTASPSPPRCAKTQLTP---PAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           SG  +P   G   + ++P+ P  A     P   PA +S      +   TP   AP  LLG
Sbjct: 297 SGASTP---GGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGSLLG 353

Query: 74  EA-SLTSPL 81
            A  L SPL
Sbjct: 354 AAPGLPSPL 362


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           PA +  + PT       T    P      + TP  I+S P  P+E   T   SAP     
Sbjct: 208 PALTTPKEPT------PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----- 256

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
               T+P    P +  + +P+  +       +  +  T +  P+ P  P+P TP  P+PT
Sbjct: 257 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 312

Query: 132 APRRSQYPSP 141
            P+     +P
Sbjct: 313 TPKEPAPTTP 322



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 21/130 (16%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P A    +PT   + ++ A  +P   A T    P+    P  P+E   T   SAP     
Sbjct: 350 PTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPS----PTTPKEPAPTTTKSAPTTTKE 402

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
            A  T+  A   P EP  + +K  A             ++  P+ P  P+P TP  P+PT
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPA---------PTTPKEPAPTTPKKPAPTTPKEPAPT 453

Query: 132 APRRSQYPSP 141
            P+    P+P
Sbjct: 454 TPKE---PAP 460



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSP 93
           P+P     T  T P   +   P E    TP+G+AP  L   A  T       P +P  +P
Sbjct: 615 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKP--AP 665

Query: 94  SKSRALCNRGLRSTSR------CTQQGLPSVP--PSPLTPLPPSPTAPRRSQYPSPGSRV 145
            +      +G  ST+         ++  P+ P  P+P TP  P+PT P     P   S V
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEV 723

Query: 146 GRGLGTGRGKLAHRVAPSKEPPE 168
                T      H+ +P +  PE
Sbjct: 724 STPTTTKEPTTIHK-SPDESTPE 745



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 21/140 (15%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           S P      +PT       T    P      +  P   +S P  P+E    TP+  AP  
Sbjct: 254 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP-- 311

Query: 71  LLGEASLTSPLALIP--PSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPL 126
                  T+P    P  P EP  +  K  A   +    T+   ++  P+ P  P+P TP 
Sbjct: 312 -------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT--PKEPAPTAPKKPAPTTPK 362

Query: 127 PPSPT-----APRRSQYPSP 141
            P+PT     AP  ++ PSP
Sbjct: 363 EPAPTTPKEPAPTTTKEPSP 382



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 10/115 (8%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRL-------LLGEASLTSPLALIPP 86
           P+P   A T    P   +C  P      TP+G+AP            E + T+P    P 
Sbjct: 594 PAPKELAPTTTKEPTSTTCDKPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 650

Query: 87  SEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP 141
           +  + +P+  +    + L  T+        S  P+P TP   +PT P+     +P
Sbjct: 651 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 705



 Score = 36.6 bits (83), Expect = 0.019
 Identities = 50/211 (23%), Positives = 84/211 (39%), Gaps = 22/211 (10%)

Query: 11  SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPR 69
           + KPA +  + P    + ++TA  +P +   T  TP  +   P  PE+    TP+  AP 
Sbjct: 463 TKKPAPTTPKEPA-PTTPKETAPTTPKKLTPT--TPEKL--APTTPEKPAPTTPEELAP- 516

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCT-QQGLPSVPPSPLTPLPP 128
                   T+P    P +  + +P+  +A      +  +  T ++  P+ P  P  P  P
Sbjct: 517 --------TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTP 567

Query: 129 SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP--SKEPPERACGSRGRST--GWAASS 184
             TAP   +  +P +       T +      +AP  +KEP    C     +T  G A ++
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627

Query: 185 PKTHA-AGQAPAAARSGRGAGPAREGSGAPS 214
           PK  A       A  + +G  P      AP+
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 658



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 10/130 (7%)

Query: 21  SPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSP 80
           +PT   S   T     P   K+  T P   +     E    TP+  AP      A  T+ 
Sbjct: 233 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 292

Query: 81  LALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP---------PSPLTPLPPSPT 131
            A   P EP  +  K  A             ++  P+ P         P+P TP  P+PT
Sbjct: 293 SAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 351

Query: 132 APRRSQYPSP 141
           AP++    +P
Sbjct: 352 APKKPAPTTP 361



 Score = 34.3 bits (77), Expect = 0.094
 Identities = 31/134 (23%), Positives = 46/134 (34%), Gaps = 6/134 (4%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P      +PT       T    P      +  P      P  P+E   T           
Sbjct: 303 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPS-PLTPLPPSPT- 131
           E + T+P    P +  + SP+  +       +S    T++  P+   S P TP  PSPT 
Sbjct: 363 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 132 ----APRRSQYPSP 141
               AP   + P+P
Sbjct: 423 TKEPAPTTPKEPAP 436



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 10/131 (7%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P  +   +PT   + ++ A  +P + A T    PA  +   P       P  + P+    
Sbjct: 420 PTTTKEPAPT---TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK---- 472

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGL-PSVP--PSPLTPLPPSP 130
           E + T+P    P +  + +P+    L        +  T + L P+ P  P+P TP  P+P
Sbjct: 473 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 532

Query: 131 TAPRRSQYPSP 141
           T P+ +   +P
Sbjct: 533 TTPKAAAPNTP 543



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 30/130 (23%), Positives = 44/130 (33%), Gaps = 7/130 (5%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P      SPT       T  P+P    +   T P   +   P E    TP+  AP   
Sbjct: 410 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 463

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
              A  T+P    P +  + +P+  + L        +  T +      P  L P  P   
Sbjct: 464 KKPAP-TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522

Query: 132 APRRSQYPSP 141
            P   + P+P
Sbjct: 523 TPTTPEEPAP 532



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/131 (23%), Positives = 49/131 (37%), Gaps = 3/131 (2%)

Query: 13  KPAASGVQS-PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           +PA +  +S PT       T + S P   K           P  P+E    TP+  AP  
Sbjct: 387 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 446

Query: 71  LLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSP 130
              E + T+P    P +  + +P+  +       + T+  T + L    P  L P  P  
Sbjct: 447 PK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 505

Query: 131 TAPRRSQYPSP 141
            AP   +  +P
Sbjct: 506 PAPTTPEELAP 516


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           PA +  + PT       T    P      + TP  I+S P  P+E   T   SAP     
Sbjct: 249 PALTTPKEPT------PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----- 297

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
               T+P    P +  + +P+  +       +  +  T +  P+ P  P+P TP  P+PT
Sbjct: 298 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 353

Query: 132 APRRSQYPSP 141
            P+     +P
Sbjct: 354 TPKEPAPTTP 363



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 21/130 (16%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P A    +PT   + ++ A  +P   A T    P+    P  P+E   T   SAP     
Sbjct: 391 PTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPS----PTTPKEPAPTTTKSAPTTTKE 443

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
            A  T+  A   P EP  + +K  A             ++  P+ P  P+P TP  P+PT
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPA---------PTTPKEPAPTTPKKPAPTTPKEPAPT 494

Query: 132 APRRSQYPSP 141
            P+    P+P
Sbjct: 495 TPKE---PAP 501



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSP 93
           P+P     T  T P   +   P E    TP+G+AP  L   A  T       P +P  +P
Sbjct: 656 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKP--AP 706

Query: 94  SKSRALCNRGLRSTSR------CTQQGLPSVP--PSPLTPLPPSPTAPRRSQYPSPGSRV 145
            +      +G  ST+         ++  P+ P  P+P TP  P+PT P     P   S V
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEV 764

Query: 146 GRGLGTGRGKLAHRVAPSKEPPE 168
                T      H+ +P +  PE
Sbjct: 765 STPTTTKEPTTIHK-SPDESTPE 786



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 21/140 (15%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           S P      +PT       T    P      +  P   +S P  P+E    TP+  AP  
Sbjct: 295 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP-- 352

Query: 71  LLGEASLTSPLALIP--PSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPL 126
                  T+P    P  P EP  +  K  A   +    T+   ++  P+ P  P+P TP 
Sbjct: 353 -------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT--PKEPAPTAPKKPAPTTPK 403

Query: 127 PPSPT-----APRRSQYPSP 141
            P+PT     AP  ++ PSP
Sbjct: 404 EPAPTTPKEPAPTTTKEPSP 423



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 10/115 (8%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRL-------LLGEASLTSPLALIPP 86
           P+P   A T    P   +C  P      TP+G+AP            E + T+P    P 
Sbjct: 635 PAPKELAPTTTKEPTSTTCDKPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 691

Query: 87  SEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP 141
           +  + +P+  +    + L  T+        S  P+P TP   +PT P+     +P
Sbjct: 692 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 746



 Score = 36.6 bits (83), Expect = 0.019
 Identities = 50/211 (23%), Positives = 84/211 (39%), Gaps = 22/211 (10%)

Query: 11  SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPR 69
           + KPA +  + P    + ++TA  +P +   T  TP  +   P  PE+    TP+  AP 
Sbjct: 504 TKKPAPTTPKEPA-PTTPKETAPTTPKKLTPT--TPEKL--APTTPEKPAPTTPEELAP- 557

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCT-QQGLPSVPPSPLTPLPP 128
                   T+P    P +  + +P+  +A      +  +  T ++  P+ P  P  P  P
Sbjct: 558 --------TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTP 608

Query: 129 SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP--SKEPPERACGSRGRST--GWAASS 184
             TAP   +  +P +       T +      +AP  +KEP    C     +T  G A ++
Sbjct: 609 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668

Query: 185 PKTHA-AGQAPAAARSGRGAGPAREGSGAPS 214
           PK  A       A  + +G  P      AP+
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 699



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 10/130 (7%)

Query: 21  SPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSP 80
           +PT   S   T     P   K+  T P   +     E    TP+  AP      A  T+ 
Sbjct: 274 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 333

Query: 81  LALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP---------PSPLTPLPPSPT 131
            A   P EP  +  K  A             ++  P+ P         P+P TP  P+PT
Sbjct: 334 SAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 392

Query: 132 APRRSQYPSP 141
           AP++    +P
Sbjct: 393 APKKPAPTTP 402



 Score = 34.3 bits (77), Expect = 0.094
 Identities = 31/134 (23%), Positives = 46/134 (34%), Gaps = 6/134 (4%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P      +PT       T    P      +  P      P  P+E   T           
Sbjct: 344 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPS-PLTPLPPSPT- 131
           E + T+P    P +  + SP+  +       +S    T++  P+   S P TP  PSPT 
Sbjct: 404 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 132 ----APRRSQYPSP 141
               AP   + P+P
Sbjct: 464 TKEPAPTTPKEPAP 477



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 10/131 (7%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P  +   +PT   + ++ A  +P + A T    PA  +   P       P  + P+    
Sbjct: 461 PTTTKEPAPT---TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK---- 513

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGL-PSVP--PSPLTPLPPSP 130
           E + T+P    P +  + +P+    L        +  T + L P+ P  P+P TP  P+P
Sbjct: 514 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 573

Query: 131 TAPRRSQYPSP 141
           T P+ +   +P
Sbjct: 574 TTPKAAAPNTP 584



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 30/130 (23%), Positives = 44/130 (33%), Gaps = 7/130 (5%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P      SPT       T  P+P    +   T P   +   P E    TP+  AP   
Sbjct: 451 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 504

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
              A  T+P    P +  + +P+  + L        +  T +      P  L P  P   
Sbjct: 505 KKPAP-TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563

Query: 132 APRRSQYPSP 141
            P   + P+P
Sbjct: 564 TPTTPEEPAP 573



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/131 (23%), Positives = 49/131 (37%), Gaps = 3/131 (2%)

Query: 13  KPAASGVQS-PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           +PA +  +S PT       T + S P   K           P  P+E    TP+  AP  
Sbjct: 428 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 487

Query: 71  LLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSP 130
              E + T+P    P +  + +P+  +       + T+  T + L    P  L P  P  
Sbjct: 488 PK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 546

Query: 131 TAPRRSQYPSP 141
            AP   +  +P
Sbjct: 547 PAPTTPEELAP 557


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           PA +  + PT       T    P      + TP  I+S P  P+E   T   SAP     
Sbjct: 301 PALTTPKEPT------PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----- 349

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
               T+P    P +  + +P+  +       +  +  T +  P+ P  P+P TP  P+PT
Sbjct: 350 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 405

Query: 132 APRRSQYPSP 141
            P+     +P
Sbjct: 406 TPKEPAPTTP 415



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 21/130 (16%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P A    +PT   + ++ A  +P   A T    P+    P  P+E   T   SAP     
Sbjct: 443 PTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPS----PTTPKEPAPTTTKSAPTTTKE 495

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
            A  T+  A   P EP  + +K  A             ++  P+ P  P+P TP  P+PT
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPA---------PTTPKEPAPTTPKKPAPTTPKEPAPT 546

Query: 132 APRRSQYPSP 141
            P+    P+P
Sbjct: 547 TPKE---PAP 553



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSP 93
           P+P     T  T P   +   P E    TP+G+AP  L   A  T       P +P  +P
Sbjct: 708 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKP--AP 758

Query: 94  SKSRALCNRGLRSTSR------CTQQGLPSVP--PSPLTPLPPSPTAPRRSQYPSPGSRV 145
            +      +G  ST+         ++  P+ P  P+P TP  P+PT P     P   S V
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEV 816

Query: 146 GRGLGTGRGKLAHRVAPSKEPPE 168
                T      H+ +P +  PE
Sbjct: 817 STPTTTKEPTTIHK-SPDESTPE 838



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 21/140 (15%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           S P      +PT       T    P      +  P   +S P  P+E    TP+  AP  
Sbjct: 347 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP-- 404

Query: 71  LLGEASLTSPLALIP--PSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPL 126
                  T+P    P  P EP  +  K  A   +    T+   ++  P+ P  P+P TP 
Sbjct: 405 -------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT--PKEPAPTAPKKPAPTTPK 455

Query: 127 PPSPT-----APRRSQYPSP 141
            P+PT     AP  ++ PSP
Sbjct: 456 EPAPTTPKEPAPTTTKEPSP 475



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 10/115 (8%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRL-------LLGEASLTSPLALIPP 86
           P+P   A T    P   +C  P      TP+G+AP            E + T+P    P 
Sbjct: 687 PAPKELAPTTTKEPTSTTCDKPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 743

Query: 87  SEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP 141
           +  + +P+  +    + L  T+        S  P+P TP   +PT P+     +P
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 798



 Score = 36.6 bits (83), Expect = 0.019
 Identities = 50/211 (23%), Positives = 84/211 (39%), Gaps = 22/211 (10%)

Query: 11  SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPR 69
           + KPA +  + P    + ++TA  +P +   T  TP  +   P  PE+    TP+  AP 
Sbjct: 556 TKKPAPTTPKEPA-PTTPKETAPTTPKKLTPT--TPEKL--APTTPEKPAPTTPEELAP- 609

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCT-QQGLPSVPPSPLTPLPP 128
                   T+P    P +  + +P+  +A      +  +  T ++  P+ P  P  P  P
Sbjct: 610 --------TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTP 660

Query: 129 SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP--SKEPPERACGSRGRST--GWAASS 184
             TAP   +  +P +       T +      +AP  +KEP    C     +T  G A ++
Sbjct: 661 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720

Query: 185 PKTHA-AGQAPAAARSGRGAGPAREGSGAPS 214
           PK  A       A  + +G  P      AP+
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 751



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 10/130 (7%)

Query: 21  SPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSP 80
           +PT   S   T     P   K+  T P   +     E    TP+  AP      A  T+ 
Sbjct: 326 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 385

Query: 81  LALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP---------PSPLTPLPPSPT 131
            A   P EP  +  K  A             ++  P+ P         P+P TP  P+PT
Sbjct: 386 SAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 444

Query: 132 APRRSQYPSP 141
           AP++    +P
Sbjct: 445 APKKPAPTTP 454



 Score = 34.3 bits (77), Expect = 0.094
 Identities = 31/134 (23%), Positives = 46/134 (34%), Gaps = 6/134 (4%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P      +PT       T    P      +  P      P  P+E   T           
Sbjct: 396 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPS-PLTPLPPSPT- 131
           E + T+P    P +  + SP+  +       +S    T++  P+   S P TP  PSPT 
Sbjct: 456 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 515

Query: 132 ----APRRSQYPSP 141
               AP   + P+P
Sbjct: 516 TKEPAPTTPKEPAP 529



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 10/131 (7%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P  +   +PT   + ++ A  +P + A T    PA  +   P       P  + P+    
Sbjct: 513 PTTTKEPAPT---TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK---- 565

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGL-PSVP--PSPLTPLPPSP 130
           E + T+P    P +  + +P+    L        +  T + L P+ P  P+P TP  P+P
Sbjct: 566 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 625

Query: 131 TAPRRSQYPSP 141
           T P+ +   +P
Sbjct: 626 TTPKAAAPNTP 636



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 30/130 (23%), Positives = 44/130 (33%), Gaps = 7/130 (5%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P      SPT       T  P+P    +   T P   +   P E    TP+  AP   
Sbjct: 503 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 556

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
              A  T+P    P +  + +P+  + L        +  T +      P  L P  P   
Sbjct: 557 KKPAP-TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615

Query: 132 APRRSQYPSP 141
            P   + P+P
Sbjct: 616 TPTTPEEPAP 625



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/131 (23%), Positives = 49/131 (37%), Gaps = 3/131 (2%)

Query: 13  KPAASGVQS-PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           +PA +  +S PT       T + S P   K           P  P+E    TP+  AP  
Sbjct: 480 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 539

Query: 71  LLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSP 130
              E + T+P    P +  + +P+  +       + T+  T + L    P  L P  P  
Sbjct: 540 PK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 598

Query: 131 TAPRRSQYPSP 141
            AP   +  +P
Sbjct: 599 PAPTTPEELAP 609


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 33/130 (25%), Positives = 52/130 (40%), Gaps = 17/130 (13%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           PA +  + PT       T    P      + TP  I+S P  P+E   T   SAP     
Sbjct: 342 PALTTPKEPT------PTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAP----- 390

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
               T+P    P +  + +P+  +       +  +  T +  P+ P  P+P TP  P+PT
Sbjct: 391 ----TTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPT 446

Query: 132 APRRSQYPSP 141
            P+     +P
Sbjct: 447 TPKEPAPTTP 456



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 36/130 (27%), Positives = 53/130 (40%), Gaps = 21/130 (16%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P A    +PT   + ++ A  +P   A T    P+    P  P+E   T   SAP     
Sbjct: 484 PTAPKKPAPT---TPKEPAPTTPKEPAPTTTKEPS----PTTPKEPAPTTTKSAPTTTKE 536

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPLPPSPT 131
            A  T+  A   P EP  + +K  A             ++  P+ P  P+P TP  P+PT
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPA---------PTTPKEPAPTTPKKPAPTTPKEPAPT 587

Query: 132 APRRSQYPSP 141
            P+    P+P
Sbjct: 588 TPKE---PAP 594



 Score = 38.1 bits (87), Expect = 0.007
 Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 20/143 (13%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSP 93
           P+P     T  T P   +   P E    TP+G+AP  L   A  T       P +P  +P
Sbjct: 749 PAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT-------PKKP--AP 799

Query: 94  SKSRALCNRGLRSTSR------CTQQGLPSVP--PSPLTPLPPSPTAPRRSQYPSPGSRV 145
            +      +G  ST+         ++  P+ P  P+P TP  P+PT P     P   S V
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETP--PPTTSEV 857

Query: 146 GRGLGTGRGKLAHRVAPSKEPPE 168
                T      H+ +P +  PE
Sbjct: 858 STPTTTKEPTTIHK-SPDESTPE 879



 Score = 37.7 bits (86), Expect = 0.008
 Identities = 38/140 (27%), Positives = 54/140 (38%), Gaps = 21/140 (15%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           S P      +PT       T    P      +  P   +S P  P+E    TP+  AP  
Sbjct: 388 SAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAP-- 445

Query: 71  LLGEASLTSPLALIP--PSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP--PSPLTPL 126
                  T+P    P  P EP  +  K  A   +    T+   ++  P+ P  P+P TP 
Sbjct: 446 -------TTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTT--PKEPAPTAPKKPAPTTPK 496

Query: 127 PPSPT-----APRRSQYPSP 141
            P+PT     AP  ++ PSP
Sbjct: 497 EPAPTTPKEPAPTTTKEPSP 516



 Score = 37.0 bits (84), Expect = 0.014
 Identities = 28/115 (24%), Positives = 45/115 (39%), Gaps = 10/115 (8%)

Query: 34  PSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRL-------LLGEASLTSPLALIPP 86
           P+P   A T    P   +C  P      TP+G+AP            E + T+P    P 
Sbjct: 728 PAPKELAPTTTKEPTSTTCDKPAPT---TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT 784

Query: 87  SEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSP 141
           +  + +P+  +    + L  T+        S  P+P TP   +PT P+     +P
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTP 839



 Score = 36.6 bits (83), Expect = 0.019
 Identities = 50/211 (23%), Positives = 84/211 (39%), Gaps = 22/211 (10%)

Query: 11  SSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPR 69
           + KPA +  + P    + ++TA  +P +   T  TP  +   P  PE+    TP+  AP 
Sbjct: 597 TKKPAPTTPKEPA-PTTPKETAPTTPKKLTPT--TPEKL--APTTPEKPAPTTPEELAP- 650

Query: 70  LLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCT-QQGLPSVPPSPLTPLPP 128
                   T+P    P +  + +P+  +A      +  +  T ++  P+ P  P  P  P
Sbjct: 651 --------TTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEP-APTTP 701

Query: 129 SPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAP--SKEPPERACGSRGRST--GWAASS 184
             TAP   +  +P +       T +      +AP  +KEP    C     +T  G A ++
Sbjct: 702 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761

Query: 185 PKTHA-AGQAPAAARSGRGAGPAREGSGAPS 214
           PK  A       A  + +G  P      AP+
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT 792



 Score = 35.8 bits (81), Expect = 0.032
 Identities = 33/130 (25%), Positives = 47/130 (36%), Gaps = 10/130 (7%)

Query: 21  SPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSP 80
           +PT   S   T     P   K+  T P   +     E    TP+  AP      A  T+ 
Sbjct: 367 TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTK 426

Query: 81  LALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVP---------PSPLTPLPPSPT 131
            A   P EP  +  K  A             ++  P+ P         P+P TP  P+PT
Sbjct: 427 SAPTTPKEPAPTTPKKPAPTTPK-EPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT 485

Query: 132 APRRSQYPSP 141
           AP++    +P
Sbjct: 486 APKKPAPTTP 495



 Score = 34.3 bits (77), Expect = 0.094
 Identities = 31/134 (23%), Positives = 46/134 (34%), Gaps = 6/134 (4%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P      +PT       T    P      +  P      P  P+E   T           
Sbjct: 437 PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPS-PLTPLPPSPT- 131
           E + T+P    P +  + SP+  +       +S    T++  P+   S P TP  PSPT 
Sbjct: 497 EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 556

Query: 132 ----APRRSQYPSP 141
               AP   + P+P
Sbjct: 557 TKEPAPTTPKEPAP 570



 Score = 33.9 bits (76), Expect = 0.12
 Identities = 31/131 (23%), Positives = 55/131 (41%), Gaps = 10/131 (7%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLG 73
           P  +   +PT   + ++ A  +P + A T    PA  +   P       P  + P+    
Sbjct: 554 PTTTKEPAPT---TPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK---- 606

Query: 74  EASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGL-PSVP--PSPLTPLPPSP 130
           E + T+P    P +  + +P+    L        +  T + L P+ P  P+P TP  P+P
Sbjct: 607 EPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAP 666

Query: 131 TAPRRSQYPSP 141
           T P+ +   +P
Sbjct: 667 TTPKAAAPNTP 677



 Score = 30.8 bits (68), Expect = 1.0
 Identities = 30/130 (23%), Positives = 44/130 (33%), Gaps = 7/130 (5%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           S P      SPT       T  P+P    +   T P   +   P E    TP+  AP   
Sbjct: 544 SAPTTPKEPSPT------TTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTT 597

Query: 72  LGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPT 131
              A  T+P    P +  + +P+  + L        +  T +      P  L P  P   
Sbjct: 598 KKPAP-TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656

Query: 132 APRRSQYPSP 141
            P   + P+P
Sbjct: 657 TPTTPEEPAP 666



 Score = 30.4 bits (67), Expect = 1.4
 Identities = 31/131 (23%), Positives = 49/131 (37%), Gaps = 3/131 (2%)

Query: 13  KPAASGVQS-PTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDL-LTPQGSAPRL 70
           +PA +  +S PT       T + S P   K           P  P+E    TP+  AP  
Sbjct: 521 EPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT 580

Query: 71  LLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSP 130
              E + T+P    P +  + +P+  +       + T+  T + L    P  L P  P  
Sbjct: 581 PK-EPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEK 639

Query: 131 TAPRRSQYPSP 141
            AP   +  +P
Sbjct: 640 PAPTTPEELAP 650


>gi|55741677 SET domain containing 1A [Homo sapiens]
          Length = 1707

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 58/197 (29%), Positives = 76/197 (38%), Gaps = 42/197 (21%)

Query: 30   QTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPPSEP 89
            Q ASP+ P    T+ +PP   S PL P E    P   APR    +   +SP+ L+PP + 
Sbjct: 1111 QEASPARP-AGPTEESPP---SAPLRPPEPPAGPPAPAPR---PDERPSSPIPLLPPPKK 1163

Query: 90   QHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSR-VGRG 148
            +       A+                  V P+P     P P  P ++++P P SR   RG
Sbjct: 1164 RRKTVSFSAI-----------------EVVPAP----EPPPATPPQAKFPGPASRKAPRG 1202

Query: 149  L-GTGRGKLAHRVAPSKEPPERA-------CGSRGRSTGWAASSPKTHA-----AGQAPA 195
            +  T R       +  K  PE          G RGR T    + P T       A  A  
Sbjct: 1203 VERTIRNLPLDHASLVKSWPEEVSRGGRSRAGGRGRLTEEEEAEPGTEVDLAVLADLALT 1262

Query: 196  AARSGRGAGPAREGSGA 212
             AR G  A PA E S A
Sbjct: 1263 PARRGLPALPAVEDSEA 1279



 Score = 39.3 bits (90), Expect = 0.003
 Identities = 31/95 (32%), Positives = 35/95 (36%), Gaps = 27/95 (28%)

Query: 119 PPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRST 178
           PPS  + LPP P+ P    Y  P S                 AP  EPPE   G      
Sbjct: 406 PPSYTSYLPPEPSRPTDQDYRPPASE----------------APPPEPPEPGGGG----- 444

Query: 179 GWAASSPKTHAAGQAPAAARSGRGAGPAREGSGAP 213
           G    SP+      +P      R A PAR GS AP
Sbjct: 445 GGGGPSPEREEVRTSP------RPASPARSGSPAP 473



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 31/131 (23%), Positives = 44/131 (33%), Gaps = 13/131 (9%)

Query: 17  SGVQSPTFHGSGRQTASPSPPRCAKTQLT----PPAIRSCPLPPEEDLLTPQGSAPRLLL 72
           +G + P+  G G  T  P+P        T    P A R  P    ++  +P  S   + +
Sbjct: 526 TGSEVPSGSGHGPCTPPPAPANFEDVAPTGSGEPGATRESPKANGQNQASPCSSGDDMEI 585

Query: 73  GEASL--TSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSP 130
            +     + P A  PP +P   P                     L   P  P   LPP P
Sbjct: 586 SDDDRGGSPPPAPTPPQQPPPPPPPPPP-------PPPYLASLPLGYPPHQPAYLLPPRP 638

Query: 131 TAPRRSQYPSP 141
             P   +YP P
Sbjct: 639 DGPPPPEYPPP 649


>gi|146219841 PNMA-like 2 [Homo sapiens]
          Length = 635

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 38/110 (34%), Positives = 46/110 (41%), Gaps = 16/110 (14%)

Query: 120 PSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTG 179
           P  LTP    PTA         G+R  R  G GRG+           PE+  GSRG +  
Sbjct: 542 PRGLTPAGAPPTAS--------GARKTRAGGRGRGRGV--------TPEKKAGSRGSAQD 585

Query: 180 WAASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLR 229
            AA S K   +  A A AR+G   G A  GS A  G  +R      P+ R
Sbjct: 586 DAAGSRKKKGSAGAGAHARAGEAKGQAPTGSKAARGKKARRGRRLPPKCR 635


>gi|239756987 PREDICTED: hypothetical protein XP_002345138 [Homo
           sapiens]
          Length = 459

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 49/116 (42%), Gaps = 9/116 (7%)

Query: 116 PSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRG 175
           P  P + L    P+  +P      + G R  R  G G G+    VA     PE A  + G
Sbjct: 110 PPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA----PESAAAAPG 165

Query: 176 RSTGWAASSPKTHAAGQAPAAARSGRGA----GPAREGSGAPSGLGSRAVPVTAPR 227
           RS    A    T +A + P A RS R A      A +  GAPS   S+A P  APR
Sbjct: 166 RSPS-PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPR 220


>gi|239746003 PREDICTED: hypothetical protein XP_002344191 [Homo
           sapiens]
          Length = 459

 Score = 44.7 bits (104), Expect = 7e-05
 Identities = 39/116 (33%), Positives = 49/116 (42%), Gaps = 9/116 (7%)

Query: 116 PSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRG 175
           P  P + L    P+  +P      + G R  R  G G G+    VA     PE A  + G
Sbjct: 110 PPAPQAFLAQRSPARASPGGGFTSAEGKRKTRPAGRGGGRTRRVVAA----PESAAAAPG 165

Query: 176 RSTGWAASSPKTHAAGQAPAAARSGRGA----GPAREGSGAPSGLGSRAVPVTAPR 227
           RS    A    T +A + P A RS R A      A +  GAPS   S+A P  APR
Sbjct: 166 RSPS-PADPGSTSSATRVPRARRSSRRALQPRHAAPDAPGAPSRSTSQATPPPAPR 220


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 59/206 (28%), Positives = 68/206 (33%), Gaps = 35/206 (16%)

Query: 14  PAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSA------ 67
           PA  G   P F       A  +PPR     L PP     P PP    + P   A      
Sbjct: 220 PAGPGGPPPPF------PAGQTPPR---PPLGPPGPPGPPGPPPPGQVLPPPLAGPPNRG 270

Query: 68  -----PRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSP 122
                P L  G+     PL  +PP  P   P         G        QQG P  PP P
Sbjct: 271 DRPPPPVLFPGQPFGQPPLGPLPPGPPPPVPGY-------GPPPGPPPPQQG-PPPPPGP 322

Query: 123 LTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAA 182
             P PP P  P  +  P P      G   G    A  V P+  PP     + G  T  + 
Sbjct: 323 FPPRPPGPLGPPLTLAPPPHL---PGPPPGAPPPAPHVNPAFFPPPT---NSGMPTSDSR 376

Query: 183 SSPKTHAAGQAPAAARSGRGAGPARE 208
             P T   G+ P   R   G  P RE
Sbjct: 377 GPPPTDPYGRPPPYDRGDYGP-PGRE 401


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 55/231 (23%), Positives = 86/231 (37%), Gaps = 8/231 (3%)

Query: 4   PDLVNQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCP-LPPEEDLLT 62
           PD + Q ++  AA+G  +P         A P+        L  P  +  P  P  +    
Sbjct: 599 PDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQPPQAPTPQAAAP 658

Query: 63  PQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSP 122
           PQ + P+   G AS  SP  ++    P  +P+      +  +      +QQ L +  P  
Sbjct: 659 PQATTPQPSPGLAS--SPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHL 716

Query: 123 LTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPP-ERACGSRGRSTGWA 181
             P     +AP  +Q P+P + V +G G G      + +P+  P    A   +G     +
Sbjct: 717 SVPASVIVSAPPPAQDPAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSS 776

Query: 182 ASSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTAPRLRDFP 232
            S P     G +P          P R  S  PS   S + P + P L   P
Sbjct: 777 PSLPHQAPLGDSPHLP----SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP 823



 Score = 32.0 bits (71), Expect = 0.47
 Identities = 41/146 (28%), Positives = 51/146 (34%), Gaps = 34/146 (23%)

Query: 12  SKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL 71
           +K A  G Q+P    S     +P+P   A   L  P   S P  P +    P G +P L 
Sbjct: 740 AKGAGLGPQAPDSQAS----PAPAPQIPAAAPLKGPGPSSSPSLPHQ---APLGDSPHL- 791

Query: 72  LGEASLTSPLALIPPSEPQHSP-SKSRALCNRGLRSTSRCTQQGLPSVP----------- 119
                  SP    PPS P   P S SR      L        Q  P++P           
Sbjct: 792 ------PSPHPTRPPSRPPSRPQSVSRPPSEPPLHPCP--PPQAPPTLPGIFVIQNQLGV 843

Query: 120 ------PSPLTPLPPSPTAPRRSQYP 139
                 P+P  P PP P    +SQ P
Sbjct: 844 PPPASNPAPTAPGPPQPPLRPQSQPP 869


>gi|74271903 chondroitin sulfate synthase 3 [Homo sapiens]
          Length = 882

 Score = 44.3 bits (103), Expect = 9e-05
 Identities = 42/138 (30%), Positives = 54/138 (39%), Gaps = 10/138 (7%)

Query: 99  LCNRGLRSTSRCTQQGLPSVPP--SPLTPLPPSPTAPRRSQYPSPGSRVGRG---LGTGR 153
           L  R  R +S C+  G  +  P      PLP   + PR+ Q P P  +  +G        
Sbjct: 34  LSERKRRGSSLCSYYGRSAAGPRAGAQQPLPQPQSRPRQEQSPPPARQDLQGPPLPEAAP 93

Query: 154 GKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGPAREG---- 209
           G  + R +P ++PP      RGR    A   P   AA   P     G  AG  R+G    
Sbjct: 94  GITSFRSSPWQQPPPLQQRRRGREPEGATGLPGAPAAEGEP-EEEDGGAAGQRRDGRPGS 152

Query: 210 SGAPSGLGSRAVPVTAPR 227
           S   SG G  A P   PR
Sbjct: 153 SHNGSGDGGAAAPSARPR 170


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 55/218 (25%), Positives = 74/218 (33%), Gaps = 32/218 (14%)

Query: 8   NQCSSKPAASGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSA 67
           N+    P     Q P   G  +  ++ SPP   K Q  PP   + P  P      PQG  
Sbjct: 210 NKPQGPPPPGKPQGPPPQGDNKSQSARSPP--GKPQGPPPQGGNQPQGPPPPPGKPQGPP 267

Query: 68  PRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPS---------- 117
           P+          P    PP +PQ  P +       G +S S  +  G P           
Sbjct: 268 PQ------GGNKPQGPPPPGKPQGPPPQG------GSKSRSSRSPPGKPQGPPPQGGNQP 315

Query: 118 --VPPSPLTPLPPSPTAPRRSQ-YPSPGSRVGRGLGTGRGKLAHRVAPSK-EPPERACGS 173
              PP P  P  P P    + Q  P PG   G     G    + R  P K + P +  G+
Sbjct: 316 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375

Query: 174 RGRS----TGWAASSPKTHAAGQAPAAARSGRGAGPAR 207
             +      G     P+   AGQ     R  +G  P+R
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413



 Score = 36.2 bits (82), Expect = 0.025
 Identities = 51/206 (24%), Positives = 72/206 (34%), Gaps = 17/206 (8%)

Query: 28  GRQTASP-SPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEASLTSPLALIPP 86
           G ++ SP SPP   K Q  PP   + P  P      PQG  P+          P    PP
Sbjct: 105 GDKSRSPRSPP--GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ------GGNKPQGPPPP 156

Query: 87  SEPQHSP----SKSRALCNRGLRSTSRCTQQGLP--SVPPSPLTPLPPSPTAPRRSQYPS 140
            +PQ  P    +KSR+  +   +      Q G      PP P  P  P P    + Q P 
Sbjct: 157 GKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216

Query: 141 PGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAASSPKTHAAGQAPAAARSG 200
           P  +       G  K     +P  +P  +    +G +       P     G  P      
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKP 274

Query: 201 RGAGPAREGSGAPSGLGSRAVPVTAP 226
           +G  P  +  G P   GS++    +P
Sbjct: 275 QGPPPPGKPQGPPPQGGSKSRSSRSP 300



 Score = 29.6 bits (65), Expect = 2.3
 Identities = 36/151 (23%), Positives = 48/151 (31%), Gaps = 23/151 (15%)

Query: 63  PQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSP 122
           PQG+ P+   G      P +  PP +PQ  P +       G +        G P  PP  
Sbjct: 36  PQGAPPQ---GGNKPQGPPS--PPGKPQGPPPQG------GNQPQGPPPPPGKPQGPPPQ 84

Query: 123 LTPLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPERACGSRGRSTGWAA 182
               P  P  P + Q P P     R   +  GK      P   PP+      G +     
Sbjct: 85  GGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGK------PQGPPPQ------GGNQPQGP 132

Query: 183 SSPKTHAAGQAPAAARSGRGAGPAREGSGAP 213
             P     G  P      +G  P  +  G P
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPP 163


>gi|239747203 PREDICTED: hypothetical protein LOC643965 [Homo
           sapiens]
          Length = 451

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 44/161 (27%), Positives = 56/161 (34%), Gaps = 15/161 (9%)

Query: 75  ASLTSPLALIPPSEPQH-SPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAP 133
           A++  P A + P   QH +  +       GL  T RC  + +P V P P           
Sbjct: 75  AAMPVPDAWVCPVAQQHLNVLEEERKAGAGLSPTQRCGPRAIPGVHPRPARQEEAQRRPA 134

Query: 134 RRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPE-----------RACGSRGRSTGWAA 182
            RS     G+   R    GR +L HR  P++  P            R  GSR RS   A 
Sbjct: 135 PRSGSHEQGAVQAR--AAGRQQLQHRQPPARGRPVRRRPAARVLRLRCRGSRARSLQQAR 192

Query: 183 SSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPV 223
              +  A G  P   R  R     R G      LG   V V
Sbjct: 193 GQQRV-AQGSGPVQRREARPGASRRRGPALQQQLGHPRVSV 232


>gi|239741003 PREDICTED: hypothetical protein LOC643965 [Homo
           sapiens]
          Length = 487

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 44/161 (27%), Positives = 56/161 (34%), Gaps = 15/161 (9%)

Query: 75  ASLTSPLALIPPSEPQH-SPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAP 133
           A++  P A + P   QH +  +       GL  T RC  + +P V P P           
Sbjct: 75  AAMPVPDAWVCPVAQQHLNVLEEERKAGAGLSPTQRCGPRAIPGVHPRPARQEEAQRRPA 134

Query: 134 RRSQYPSPGSRVGRGLGTGRGKLAHRVAPSKEPPE-----------RACGSRGRSTGWAA 182
            RS     G+   R    GR +L HR  P++  P            R  GSR RS   A 
Sbjct: 135 PRSGSHEQGAVQAR--AAGRQQLQHRQPPARGRPVRRRPAARVLRLRCRGSRARSLQQAR 192

Query: 183 SSPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPV 223
              +  A G  P   R  R     R G      LG   V V
Sbjct: 193 GQQRV-AQGSGPVQRREARPGASRRRGPALQQQLGHPRVSV 232


>gi|122937241 SH3 and multiple ankyrin repeat domains 3 [Homo sapiens]
          Length = 1747

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 61/219 (27%), Positives = 74/219 (33%), Gaps = 38/219 (17%)

Query: 14   PAASGVQSPTFHGSG----RQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGS--- 66
            P ++ +Q P   G G     QTA P PP        PP   S P PP     T + S   
Sbjct: 814  PRSTSMQDPVREGRGIPPPPQTAPPPPPAPYYFDSGPPPAFSPPPPPGRAYDTVRSSFKP 873

Query: 67   --APRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLT 124
                RL  G A L  P A + P        ++R++    +   S       P  PP+   
Sbjct: 874  GLEARLGAGAAGLYEPGAALGPLPYPERQKRARSMI---ILQDSAPESGDAPRPPPAATP 930

Query: 125  PLPPSPTAPRRSQYPSPGSRVGRGLGTGRGKLAHRVAPSK---------------EPPER 169
            P  P     RR + P P S     LG     L    APSK               +  ER
Sbjct: 931  PERPK----RRPRPPGPDSPYAN-LGAFSASL---FAPSKPQRRKSPLVKQLQVEDAQER 982

Query: 170  AC---GSRGRSTGWAASSPKTHAAGQAPAAARSGRGAGP 205
            A    GS G   G  A  P     G  P     G G GP
Sbjct: 983  AALAVGSPGPGGGSFAREPSPTHRGPRPGGLDYGAGDGP 1021



 Score = 28.9 bits (63), Expect = 3.9
 Identities = 43/193 (22%), Positives = 64/193 (33%), Gaps = 17/193 (8%)

Query: 32   ASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLL-LGEASLTSPLALIPPSEPQ 90
            ASP+    +   +  PA R     P E+  +P+     +L + + SL  P  LI      
Sbjct: 1173 ASPAFSPRSPAWIPVPARREAEKVPREERKSPEDKKSMILSVLDTSLQRPAGLIVV---- 1228

Query: 91   HSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRRSQYPSPGSRVGRGLG 150
            H+ S  +     G     R    G P + P+P+     +   P     P  G+    G G
Sbjct: 1229 HATSNGQEPSRLGGAEEER---PGTPELAPAPMQSAAVAEPLPSPRAQPPGGTPADAGPG 1285

Query: 151  TGRGKLAHRVAPSKEPPERACGSRGRSTG------WAASSPKTHAAGQAPAAARSGRGAG 204
             G  +    +  +   P     S    T            P+  A G   A   +G G  
Sbjct: 1286 QGSSEEEPELVFAVNLPPAQLSSSDEETREELARIGLVPPPEEFANGVLLATPLAGPGPS 1345

Query: 205  PA---REGSGAPS 214
            P       SG PS
Sbjct: 1346 PTTVPSPASGKPS 1358



 Score = 28.5 bits (62), Expect = 5.2
 Identities = 34/126 (26%), Positives = 45/126 (35%), Gaps = 9/126 (7%)

Query: 17   SGVQSPTFHGSGRQTASPSPPRCAKTQLTPPAIRSCPLPPEEDLLTPQGSAPRLLLGEAS 76
            S  +SP   G G   +     R    +  P  ++   L   E L    G A R       
Sbjct: 1563 SAQRSPGGPGGGASYSVRPSGRYPVARRAPSPVKPASLERVEGLGAGAGGAGRPF----G 1618

Query: 77   LTSPLALIPPS-EPQHSPSKSRALCNRGLRSTSRCTQQGLPSVPPSPLTPLPPSPTAPRR 135
            LT P  L   S    H P + R +    +RS S  ++   PS  PSP +   P    PRR
Sbjct: 1619 LTPPTILKSSSLSIPHEPKEVRFV----VRSVSARSRSPSPSPLPSPASGPGPGAPGPRR 1674

Query: 136  SQYPSP 141
                 P
Sbjct: 1675 PFQQKP 1680


>gi|148747864 JAW1-related protein isoform a [Homo sapiens]
          Length = 903

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 66/233 (28%), Positives = 81/233 (34%), Gaps = 74/233 (31%)

Query: 58  EDLLTPQGSAPRLLLGEASLTSPLALIPPSEPQHSPSKSRALCNRGLRSTSRCTQQGLP- 116
           E  LT +G   R   G+    SP A+ P   P  SP+ SR+       S +  T  GL  
Sbjct: 163 ERFLTRRGRKSRSSPGD----SPSAVSPNLSPSASPTSSRS------NSLTVPTPPGLDV 212

Query: 117 -SVPPSPLTPLPPSPTAPRRSQYPSPGS-RVGRGLG---------TGRGKLAHRVAP--- 162
            S PPSPL   PP          P PG   V +GL            +G+LA R  P   
Sbjct: 213 CSGPPSPLPGAPPQKGDEADVSSPHPGEPNVPKGLADRKQNDQRKVSQGRLAPRPPPVEK 272

Query: 163 SKE----------------------------------------PPERACGSRGRSTGWAA 182
           SKE                                        P E   G +   TGW  
Sbjct: 273 SKEIAIEQKENFDPLQYPETTPKGLAPVTNSSGKMALNSPQPGPVESELGKQLLKTGWEG 332

Query: 183 S----SPKTHAAGQAPAAARSGRGAGPAREGSGAPSGLGSRAVPVTA--PRLR 229
           S    SP   AAG  P A+   +G GPA E  G  +G  +   P  +  P LR
Sbjct: 333 SPLPRSPTQDAAGVGPPAS---QGRGPAGEPMGPEAGSKAELPPTVSRPPLLR 382


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.130    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,271,290
Number of Sequences: 37866
Number of extensions: 919288
Number of successful extensions: 11269
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 1380
Number of HSP's that attempted gapping in prelim test: 7156
Number of HSP's gapped (non-prelim): 4150
length of query: 233
length of database: 18,247,518
effective HSP length: 99
effective length of query: 134
effective length of database: 14,498,784
effective search space: 1942837056
effective search space used: 1942837056
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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