Guide to the Human Genome
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Search of human proteins with 239740955

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239740955 PREDICTED: similar to c114 SLIT-like testicular
protein isoform 1 [Homo sapiens]
         (1635 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239740955 PREDICTED: similar to c114 SLIT-like testicular pro...  3310   0.0  
gi|239740953 PREDICTED: similar to c114 SLIT-like testicular pro...  3281   0.0  
gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]        3248   0.0  
gi|110665701 leucine rich repeat containing 37A [Homo sapiens]       3242   0.0  
gi|75677612 leucine rich repeat containing 37, member A3 [Homo s...  3231   0.0  
gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo ...  1737   0.0  
gi|53829385 leucine rich repeat containing 37B [Homo sapiens]         759   0.0  
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                  106   2e-22
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                  106   2e-22
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                  106   2e-22
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                   106   2e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ...    95   6e-19
gi|224458301 family with sequence similarity 186, member A [Homo...    92   4e-18
gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]              88   8e-17
gi|91982772 mucin 17 [Homo sapiens]                                    87   1e-16
gi|151301154 mucin 6, gastric [Homo sapiens]                           86   2e-16
gi|116284392 mucin 2 precursor [Homo sapiens]                          84   1e-15
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]       83   2e-15
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]        80   1e-14
gi|110349719 titin isoform N2-A [Homo sapiens]                         80   2e-14
gi|222352122 hypothetical protein LOC284297 [Homo sapiens]             79   3e-14
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    79   4e-14
gi|146134388 YLP motif containing 1 [Homo sapiens]                     77   1e-13
gi|238624188 diffuse panbronchiolitis critical region 1 protein ...    75   4e-13
gi|149773456 hypothetical protein LOC643314 [Homo sapiens]             75   4e-13
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        74   1e-12
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]          74   1e-12
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]          74   1e-12
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]          74   1e-12
gi|16554449 zonadhesin isoform 3 [Homo sapiens]                        72   4e-12

>gi|239740955 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 1 [Homo sapiens]
          Length = 1635

 Score = 3310 bits (8583), Expect = 0.0
 Identities = 1635/1635 (100%), Positives = 1635/1635 (100%)

Query: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
            MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620

Query: 1621 DSEAPTEEEESEALP 1635
            DSEAPTEEEESEALP
Sbjct: 1621 DSEAPTEEEESEALP 1635


>gi|239740953 PREDICTED: similar to c114 SLIT-like testicular protein
            isoform 2 [Homo sapiens]
          Length = 1700

 Score = 3281 bits (8508), Expect = 0.0
 Identities = 1620/1620 (100%), Positives = 1620/1620 (100%)

Query: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
            MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140

Query: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
            LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620



 Score = 35.4 bits (80), Expect = 0.46
 Identities = 19/31 (61%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 1607 HRRSLQEDE--EGFSRDSEAPTEEEESEALP 1635
            H++S  ED+       DSEAPTEEEESEALP
Sbjct: 1670 HKKSSNEDKILNRDPGDSEAPTEEEESEALP 1700


>gi|116325993 c114 SLIT-like testicular protein [Homo sapiens]
          Length = 1700

 Score = 3248 bits (8422), Expect = 0.0
 Identities = 1606/1620 (99%), Positives = 1608/1620 (99%)

Query: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPP+ W
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPDSW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTET HSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETRHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIE NNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHP EADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPHEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620



 Score = 35.4 bits (80), Expect = 0.46
 Identities = 19/31 (61%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 1607 HRRSLQEDE--EGFSRDSEAPTEEEESEALP 1635
            H++S  ED+       DSEAPTEEEESEALP
Sbjct: 1670 HKKSSNEDKILNRDPGDSEAPTEEEESEALP 1700


>gi|110665701 leucine rich repeat containing 37A [Homo sapiens]
          Length = 1700

 Score = 3242 bits (8407), Expect = 0.0
 Identities = 1606/1620 (99%), Positives = 1607/1620 (99%)

Query: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
            M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1    MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGITRQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140
            TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA
Sbjct: 1141 FIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRL SPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLTSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDR KDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRT K
Sbjct: 1261 PAKALPQVRDRSKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTTK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSA SE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSALSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620



 Score = 35.4 bits (80), Expect = 0.46
 Identities = 19/31 (61%), Positives = 22/31 (70%), Gaps = 2/31 (6%)

Query: 1607 HRRSLQEDE--EGFSRDSEAPTEEEESEALP 1635
            H++S  ED+       DSEAPTEEEESEALP
Sbjct: 1670 HKKSSNEDKILNRDPGDSEAPTEEEESEALP 1700


>gi|75677612 leucine rich repeat containing 37, member A3 [Homo
            sapiens]
          Length = 1634

 Score = 3231 bits (8378), Expect = 0.0
 Identities = 1598/1635 (97%), Positives = 1610/1635 (98%), Gaps = 1/1635 (0%)

Query: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
            MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW
Sbjct: 1    MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60

Query: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
            SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP
Sbjct: 61   SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120

Query: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
            LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGII QLSTPQSQKQTL
Sbjct: 121  LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTL 180

Query: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
            QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181  QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ
Sbjct: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
            QQPVQPSES REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT
Sbjct: 361  QQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
            IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
            QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
            QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541  QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
            LDLELTITTKPTTEVKPSPTTEETSTQ PDLGLAIIPEPTTETGHSTALEKTTAPRPDRV
Sbjct: 721  LDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
            QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM
Sbjct: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840

Query: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900
            LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN
Sbjct: 841  LSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENN 900

Query: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960
            LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW
Sbjct: 901  LTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAW 960

Query: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIL 1020
            HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI+
Sbjct: 961  HGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIV 1020

Query: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKNY 1080
            PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNT HCPEEASVGNPEGAFMKVLQARKNY
Sbjct: 1021 PSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNY 1080

Query: 1081 TSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLLP 1140
            TSTELI+EPEEPSDSSGINLSGFGSEQLDTNDESD  STL YILPYFSAVNLDVKSLLLP
Sbjct: 1081 TSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLP 1140

Query: 1141 LIKLPTTGNSLAKIQTVGQNRQRVKRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENA 1200
             IKLPTTGNSLAKIQTVG+NRQR+ RVLMGPRSIQKRHFKEVGRQSIRREQGAQASVEN 
Sbjct: 1141 FIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENT 1200

Query: 1201 AEEKRLGSPAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260
            AEEKRLGSPAPRE++QPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS
Sbjct: 1201 AEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSS 1260

Query: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPK 1320
            PAKALPQVRDRWKDLTHAISILESAKARVTN KTSKPIVH+RKKYRFHKTRS +THRTPK
Sbjct: 1261 PAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPK 1320

Query: 1321 VKKSPKVRKKSYLSRLMLANRLPFSAAKSLINSPSQGAFSSLGDLSPQENPFLEVSAPSE 1380
            VKKSPKVRKKSYLSRLML+NRLPFSAAKSLINSPSQGAFSSL DLSPQENPFLEVSAPSE
Sbjct: 1321 VKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSE 1380

Query: 1381 HFIEKNNTKHTTARNAFEENDFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440
            HFIE NNTK TTARNAFEEN FMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ
Sbjct: 1381 HFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQ 1440

Query: 1441 TETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQLTQQLQSLIPNNNVRRLIAHVIRT 1500
            TETKWEYNNVGTD SPEPKSFNYPLLSSPGDQFEIQLTQQLQS+IPNNNVRRLIAHVIRT
Sbjct: 1441 TETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRT 1500

Query: 1501 LKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKASKIEWDTDQWKIENYINESTEAQS 1560
            LKMDCSGAHVQVTCAKL+SRTGHLMKLLSGQQEVKASKIEWDTDQWK ENYINESTEAQS
Sbjct: 1501 LKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQS 1560

Query: 1561 EQKEKSLELKKEVPGYGYTDKLILALIVTGILTILIILFCLIVICCHRRSLQEDEEGFSR 1620
            EQKEKSLE  KE+PGYGYT KLILALIVTGILTILIIL CLI ICCHRRSLQEDEEGFSR
Sbjct: 1561 EQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSR 1620

Query: 1621 DSEAPTEEEESEALP 1635
            DSEAPT EEESEALP
Sbjct: 1621 DSEAPT-EEESEALP 1634


>gi|239745855 PREDICTED: hypothetical protein XP_002343606 [Homo
           sapiens]
          Length = 870

 Score = 1737 bits (4498), Expect = 0.0
 Identities = 853/870 (98%), Positives = 855/870 (98%)

Query: 1   MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPW 60
           M+SAQCPAL CVMS LRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE W
Sbjct: 1   MSSAQCPALVCVMSRLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPESW 60

Query: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP 120
           SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE P
Sbjct: 61  SSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGEQP 120

Query: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTL 180
           LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGI RQLSTPQSQKQTL
Sbjct: 121 LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIARQLSTPQSQKQTL 180

Query: 181 QNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240
           QNEYSSTDTPYP SLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ
Sbjct: 181 QNEYSSTDTPYPSSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQ 240

Query: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
           EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK
Sbjct: 241 EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300

Query: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
           PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV PMEHELSISEQ
Sbjct: 301 PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVSPMEHELSISEQ 360

Query: 361 QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
           QQPVQPSES REVESS TQQETPGQPPEHHEVTVSPPGHHQTHHL SPSVSVKPPDVQLT
Sbjct: 361 QQPVQPSESSREVESSLTQQETPGQPPEHHEVTVSPPGHHQTHHLDSPSVSVKPPDVQLT 420

Query: 421 IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
           IAAEPSAEVGTSLVHQEAT RLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF
Sbjct: 421 IAAEPSAEVGTSLVHQEATARLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480

Query: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
           QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT
Sbjct: 481 QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540

Query: 541 QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
           QATVQPLDLGFTITPES TEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH
Sbjct: 541 QATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           PVSPSVTVQLLDLGLTITPEPTTEVGHST PKRTIVSPKHPEVTLPHPDQVQTQHSHLTR
Sbjct: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTAPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
           ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP
Sbjct: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
           LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP PDRV
Sbjct: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPHPDRV 780

Query: 781 QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
           Q+LHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEE KASTSTNICELCTCGDEM
Sbjct: 781 QSLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEQKASTSTNICELCTCGDEM 840

Query: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870
           LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL
Sbjct: 841 LSCIDLNPEQRLRQVPVPEPNTHNGTFTIL 870


>gi|53829385 leucine rich repeat containing 37B [Homo sapiens]
          Length = 947

 Score =  759 bits (1959), Expect = 0.0
 Identities = 403/604 (66%), Positives = 455/604 (75%), Gaps = 41/604 (6%)

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            EL     E P  P +  + Q  +     NP   +D     +      QLL L   + P  
Sbjct: 240  ELRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPS- 298

Query: 622  TTEVGHSTPPKRTIVS----PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT--PK 675
            T +   + PP+ ++ S    P + EVT+  P + Q  H +L + TV+P D+  T+T  PK
Sbjct: 299  TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQA-HYNLPKFTVKPADVEVTMTSEPK 357

Query: 676  SMTE---------------VEPS-TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
            + TE                EPS TAL TT PPP HPEVTLPPSDKGQAQHSHLT+ATVQ
Sbjct: 358  NETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHLTEATVQ 417

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
            PLDLEL+ITT+PTTEVKPSPTTEETS QPPD GLAI PEPTTE GHSTALEKT AP PD+
Sbjct: 418  PLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTRAPHPDQ 477

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDE 839
            VQTLHRSLTEVTGPPT+LE +QDSLVQSE        TAPEE KASTSTNICELCTCGDE
Sbjct: 478  VQTLHRSLTEVTGPPTKLESSQDSLVQSE--------TAPEEQKASTSTNICELCTCGDE 529

Query: 840  MLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILREN 899
             LSC+ L+P+QRLRQVPVPEP+T+NG FT LNFQGNYISY+DGNVWKAYSWTEKLIL EN
Sbjct: 530  TLSCVGLSPKQRLRQVPVPEPDTYNGIFTTLNFQGNYISYLDGNVWKAYSWTEKLILSEN 589

Query: 900  NLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQA 959
             LTEL KDSFEGLL LQYLDLSCNKI+ IER TFE LPFL++INL CN+IT+LS GTFQA
Sbjct: 590  YLTELPKDSFEGLLYLQYLDLSCNKIRYIERQTFESLPFLQYINLGCNLITKLSLGTFQA 649

Query: 960  WHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLI 1019
            WHGMQFLH LILN NPLTTVEDPYLF+LPALKYLDMGTT + LTTLKNIL MTVELEKLI
Sbjct: 650  WHGMQFLHNLILNRNPLTTVEDPYLFELPALKYLDMGTTHITLTTLKNILTMTVELEKLI 709

Query: 1020 LPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTIHCPEEASVGNPEGAFMKVLQARKN 1079
            LPSHMACCLCQFKNSIEAVCKTVKLHCN+ACLTN+IHCPEEASVGNPEGAFMK+LQARK 
Sbjct: 710  LPSHMACCLCQFKNSIEAVCKTVKLHCNTACLTNSIHCPEEASVGNPEGAFMKMLQARKQ 769

Query: 1080 YTSTELIVEPEEPSDSSGINLSGFGSEQLDTNDESDFISTLRYILPYFSAVNLDVKSLLL 1139
            + ST+L +E E PSDSSGINLSGFG +QL    E      LR ++P     N DV+  + 
Sbjct: 770  HMSTQLTIESEAPSDSSGINLSGFGGDQL----EIQLTEQLRSLIP-----NEDVRKFMS 820

Query: 1140 PLIK 1143
             +I+
Sbjct: 821  HVIR 824



 Score =  484 bits (1247), Expect = e-136
 Identities = 286/539 (53%), Positives = 329/539 (61%), Gaps = 81/539 (15%)

Query: 13  MSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESP 72
           MS LRFWGPWPLL WQLL LLVKEAQPL WVKDPLQLTSNPLGPPEPWSS SSH P ESP
Sbjct: 1   MSWLRFWGPWPLLTWQLLSLLVKEAQPLVWVKDPLQLTSNPLGPPEPWSSRSSHLPWESP 60

Query: 73  HAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQD 132
           HAP  PA P DFD+LGPSASS+M A PQE TENL PFL   DSAGELPL PE FLA+ QD
Sbjct: 61  HAPAPPAAPGDFDYLGPSASSQMSALPQEPTENLAPFLKELDSAGELPLGPEPFLAAHQD 120

Query: 133 LKDKLSPQERLPVSPKKLKKD--------PAQRW-------------------------- 158
           L DK +P+ERLP     L +D        P  +W                          
Sbjct: 121 LNDKRTPEERLPEVVPLLNRDQNQALVQLPRLKWVQTTDLDRAAGHQADEILVPLDSKVS 180

Query: 159 --------------------SLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
                               SL EI+GI  QLS PQ QKQTL ++Y S DT YPGSLPPE
Sbjct: 181 RPTKFVVSPKNLKKDLAERWSLPEIVGIPHQLSKPQRQKQTLPDDYLSMDTLYPGSLPPE 240

Query: 199 LRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQ 258
           LRV +DEPPGP EQVG SQFHLEP++QNPETLEDIQSSSLQ+EAPAQL QL +E   S Q
Sbjct: 241 LRVNADEPPGPPEQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLPQEVEPSTQ 300

Query: 259 QEAPALPPESSMESL--TLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
           QEAPALPPESSMESL  T  NHEV+VQPPGEDQA+Y+LP  TVKPADVEVT+TSEP NET
Sbjct: 301 QEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVTMTSEPKNET 360

Query: 317 ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP-----VQPSESPR 371
           ES+QAQQE PIQ PEE EPS+T       PP  P E  L  S++ Q       + +  P 
Sbjct: 361 ESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHP-EVTLPPSDKGQAQHSHLTEATVQPL 419

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGT 431
           ++E S T + T        EV  SP          +   S +PPD  L I  EP+ E+G 
Sbjct: 420 DLELSITTEPTT-------EVKPSP---------TTEETSAQPPDPGLAITPEPTTEIGH 463

Query: 432 SLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNEN 490
           S   ++           +     +  GPP   ESS+++    VQ ET+ +  +   + N
Sbjct: 464 STALEKTRAPHPDQVQTLHRSLTEVTGPPTKLESSQDS---LVQSETAPEEQKASTSTN 519



 Score =  176 bits (447), Expect = 1e-43
 Identities = 99/197 (50%), Positives = 126/197 (63%), Gaps = 1/197 (0%)

Query: 1417 TNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDPSPEPKSFNYPLLSSPGDQFEIQ 1476
            TN  H PE  S G        + Q   +     +  +      S    L    GDQ EIQ
Sbjct: 742  TNSIHCPEEASVGNPEGAFMKMLQARKQHMSTQLTIESEAPSDSSGINLSGFGGDQLEIQ 801

Query: 1477 LTQQLQSLIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLISRTGHLMKLLSGQQEVKA 1536
            LT+QL+SLIPN +VR+ ++HVIRTLKM+CS  HVQ +CAKL+ RTG LMKLLS QQE KA
Sbjct: 802  LTEQLRSLIPNEDVRKFMSHVIRTLKMECSETHVQGSCAKLMLRTGLLMKLLSEQQEAKA 861

Query: 1537 SKIEWDTDQWKIENYINESTEAQSEQKEKSLELKKEVPGYGYTDKLILALIVTGILTILI 1596
              +EWDTDQ K  NYINE+ E   ++++KS EL KEVPG  Y +KLI A+ VT IL ILI
Sbjct: 862  LNVEWDTDQQK-TNYINENMEQNEQKEQKSSELMKEVPGDDYKNKLIFAISVTVILIILI 920

Query: 1597 ILFCLIVICCHRRSLQE 1613
            I+FCLI +  H+R+ ++
Sbjct: 921  IIFCLIEVNSHKRASEK 937



 Score =  116 bits (290), Expect = 2e-25
 Identities = 97/286 (33%), Positives = 124/286 (43%), Gaps = 54/286 (18%)

Query: 447 NDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA 506
           N  EPP     GPP      E+ G      E   Q+PE + +   S  Q+EA A+  Q  
Sbjct: 244 NADEPP-----GPP------EQVGLSQFHLEPKSQNPETLEDIQSSSLQEEAPAQLLQLP 292

Query: 507 EEGESSLTHQEAPAQTPE----------FPNVVVAQPP----EHSHLTQATVQPLDLGFT 552
           +E E S T QEAPA  PE            + V  QPP     H +L + TV+P D+  T
Sbjct: 293 QEVEPS-TQQEAPALPPESSMESLAQTPLNHEVTVQPPGEDQAHYNLPKFTVKPADVEVT 351

Query: 553 ITPESKTEVELSPTMKETPTQPPKKVVPQ---LRV------YQGVTNPTPGQDQAQHPVS 603
           +T E K E E +   +E P QPP++  P    LR       +  VT P   + QAQH   
Sbjct: 352 MTSEPKNETESTQAQQEAPIQPPEEAEPSSTALRTTDPPPEHPEVTLPPSDKGQAQHSHL 411

Query: 604 PSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL------------------ 645
              TVQ LDL L+IT EPTTEV  S   + T   P  P + +                  
Sbjct: 412 TEATVQPLDLELSITTEPTTEVKPSPTTEETSAQPPDPGLAITPEPTTEIGHSTALEKTR 471

Query: 646 -PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA 690
            PHPDQVQT H  LT  T  P  L  +      +E  P     +T+
Sbjct: 472 APHPDQVQTLHRSLTEVTGPPTKLESSQDSLVQSETAPEEQKASTS 517


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 233

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 234 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 293

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 294 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 351

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 352 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 408

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 409 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 463

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 464 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 570

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 687

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 688 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 746

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 747 SAEPTPKALENSPKEPGVPTTKTPAATKPE 776



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 190/814 (23%), Positives = 276/814 (33%), Gaps = 176/814 (21%)

Query: 35  KEAQPLEWVK-DPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
           KE Q +E      L  TS  L  P P +  ++  P     A T P +P            
Sbjct: 174 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-----ALTTPKEP------------ 216

Query: 94  EMPAPPQE--STENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
             P  P+E  ST    P   T  SA   P EP    A         +P+E  P + K   
Sbjct: 217 -TPTTPKEPASTTPKEPTPTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTK--- 268

Query: 152 KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
            +PA               +TP+    T   E + T T    + P E    + + P P+ 
Sbjct: 269 -EPAP--------------TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 313

Query: 212 QVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSME 271
              P+     P+   P T ++          PA  P   E  P++ ++ AP  P + +  
Sbjct: 314 PKEPAP--TTPKEPTPTTPKE----------PA--PTTKEPAPTTPKEPAPTAPKKPAP- 358

Query: 272 SLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPE 331
             T P       P          P+ T        T  S PT   E +    ++    P+
Sbjct: 359 --TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 416

Query: 332 EVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE----SPREVESSPTQQETPGQPP 387
           E  P+ T++ AP  P  P      +  ++  P  P E    +P+E   + T++  P  P 
Sbjct: 417 EPSPTTTKEPAPTTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 472

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
           E    T                               P     T+      TT    +  
Sbjct: 473 EPAPTT-------------------------------PKETAPTTPKKLTPTTPEKLAPT 501

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
             E PA         P + EE  P      T+ + P P   E P+PT  +AAA  P T +
Sbjct: 502 TPEKPA---------PTTPEELAP------TTPEEPTPTTPEEPAPTTPKAAA--PNTPK 544

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG--FTITPESKTEVELSP 565
           E   +   + AP  TP+ P      P E +  T     P  L      TP+     EL+P
Sbjct: 545 EPAPTTPKEPAPT-TPKEP--APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 601

Query: 566 TMKETPTQP----PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
           T  + PT      P    P+     G    TP +     P  P+ T          TP+ 
Sbjct: 602 TTTKEPTSTTCDKPAPTTPK-----GTAPTTPKEPAPTTPKEPAPT----------TPKG 646

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           T       P   T   P  P+   P   +  T  +    A   P +   T TPK      
Sbjct: 647 TAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTT 704

Query: 682 PSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PS 738
           P     TT   PPP   EV+ P                        T T +PTT  K P 
Sbjct: 705 PKKPAPTTPETPPPTTSEVSTP------------------------TTTKEPTTIHKSPD 740

Query: 739 PTTEETSTQPPDLGLAIIPE----PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP 794
            +T E S +P    L   P+    PTT+T  +T  E TT  +    +   R+  E T   
Sbjct: 741 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 800

Query: 795 TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
            ++   +++   +E  T++K +TA      ST+T
Sbjct: 801 PKM--TKETATTTEKTTESK-ITATTTQVTSTTT 831



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 186/835 (22%), Positives = 281/835 (33%), Gaps = 148/835 (17%)

Query: 53  PLGPPEPWSSHSSH-FPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLD 111
           P  P EP S+      P     APT P +P       P+ +   P  P+E          
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT----- 266

Query: 112 TWDSAGELPLEPEQFLASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEI 163
           T + A   P EP      +       S    P+E  P +PKK      K+PA        
Sbjct: 267 TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP------- 319

Query: 164 IGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
                  +TP+    T   E + T      + P E    + + P P+    P+     P+
Sbjct: 320 -------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPK 370

Query: 224 TQNPETLEDIQSSSLQQEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
              P T ++   ++ ++ AP      P   +E   +  + AP  P E S  +   P    
Sbjct: 371 EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 430

Query: 281 SVQP---------------PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQA 321
             +P               P         P  T KPA    T   EP      ET  +  
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTP 487

Query: 322 QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV 373
           ++ TP   PE++ P+  ++ AP  P    P  P E   +  E+  P  P      +P+E 
Sbjct: 488 KKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546

Query: 374 ------ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
                 E +PT  + P           +P G   T  L  P+ +         +A   + 
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 605

Query: 428 EVGTSLVHQEATTRLSGSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-- 477
           E  ++   + A T   G+      EP P       P  P+ +     +E  P   ++   
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 665

Query: 478 -----TSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ 532
                T+ + P    ++ P+PT  +  A  P T +E   +   + AP  TPE P      
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------ 716

Query: 533 PPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
           PP  S ++  T          +P+  T E+   PT K     P +  VP        T  
Sbjct: 717 PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTK 768

Query: 592 TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
           TP   +      P +T        T   + TTE    T P+ T  +PK  + T    ++ 
Sbjct: 769 TPAATK------PEMT--------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK- 813

Query: 652 QTQHSHLTRATVQPLDLG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLP 701
            T  S +T  T Q           F IT    T + P        +TT      PE T  
Sbjct: 814 -TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 872

Query: 702 PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTT 761
           P D+  A +S  T    Q          KPT   K   +T++  T P        P P  
Sbjct: 873 PKDR--ATNSKATTPKPQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 920

Query: 762 ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
            T     L  T+      +QT  R          E+ P  +    +E  T +  L
Sbjct: 921 MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 975



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 96/386 (24%), Positives = 138/386 (35%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 177 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 236

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 237 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 293

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 294 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 346

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 347 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 395

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 396 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 449

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 450 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 506

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAP 532



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 101 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 159

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 160 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 219

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 220 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 271

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 272 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 305



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 718  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 777

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 778  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 826


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 274

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 275 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 334

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 335 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 392

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 393 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 449

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 450 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 504

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 505 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 611

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 728

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 729 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 787

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 788 SAEPTPKALENSPKEPGVPTTKTPAATKPE 817



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 190/814 (23%), Positives = 276/814 (33%), Gaps = 176/814 (21%)

Query: 35  KEAQPLEWVK-DPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
           KE Q +E      L  TS  L  P P +  ++  P     A T P +P            
Sbjct: 215 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-----ALTTPKEP------------ 257

Query: 94  EMPAPPQE--STENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
             P  P+E  ST    P   T  SA   P EP    A         +P+E  P + K   
Sbjct: 258 -TPTTPKEPASTTPKEPTPTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTK--- 309

Query: 152 KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
            +PA               +TP+    T   E + T T    + P E    + + P P+ 
Sbjct: 310 -EPAP--------------TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 354

Query: 212 QVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSME 271
              P+     P+   P T ++          PA  P   E  P++ ++ AP  P + +  
Sbjct: 355 PKEPAP--TTPKEPTPTTPKE----------PA--PTTKEPAPTTPKEPAPTAPKKPAP- 399

Query: 272 SLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPE 331
             T P       P          P+ T        T  S PT   E +    ++    P+
Sbjct: 400 --TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 457

Query: 332 EVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE----SPREVESSPTQQETPGQPP 387
           E  P+ T++ AP  P  P      +  ++  P  P E    +P+E   + T++  P  P 
Sbjct: 458 EPSPTTTKEPAPTTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 513

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
           E    T                               P     T+      TT    +  
Sbjct: 514 EPAPTT-------------------------------PKETAPTTPKKLTPTTPEKLAPT 542

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
             E PA         P + EE  P      T+ + P P   E P+PT  +AAA  P T +
Sbjct: 543 TPEKPA---------PTTPEELAP------TTPEEPTPTTPEEPAPTTPKAAA--PNTPK 585

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG--FTITPESKTEVELSP 565
           E   +   + AP  TP+ P      P E +  T     P  L      TP+     EL+P
Sbjct: 586 EPAPTTPKEPAPT-TPKEP--APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 642

Query: 566 TMKETPTQP----PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
           T  + PT      P    P+     G    TP +     P  P+ T          TP+ 
Sbjct: 643 TTTKEPTSTTCDKPAPTTPK-----GTAPTTPKEPAPTTPKEPAPT----------TPKG 687

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           T       P   T   P  P+   P   +  T  +    A   P +   T TPK      
Sbjct: 688 TAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTT 745

Query: 682 PSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PS 738
           P     TT   PPP   EV+ P                        T T +PTT  K P 
Sbjct: 746 PKKPAPTTPETPPPTTSEVSTP------------------------TTTKEPTTIHKSPD 781

Query: 739 PTTEETSTQPPDLGLAIIPE----PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP 794
            +T E S +P    L   P+    PTT+T  +T  E TT  +    +   R+  E T   
Sbjct: 782 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 841

Query: 795 TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
            ++   +++   +E  T++K +TA      ST+T
Sbjct: 842 PKM--TKETATTTEKTTESK-ITATTTQVTSTTT 872



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 186/835 (22%), Positives = 281/835 (33%), Gaps = 148/835 (17%)

Query: 53   PLGPPEPWSSHSSH-FPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLD 111
            P  P EP S+      P     APT P +P       P+ +   P  P+E          
Sbjct: 259  PTTPKEPASTTPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT----- 307

Query: 112  TWDSAGELPLEPEQFLASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEI 163
            T + A   P EP      +       S    P+E  P +PKK      K+PA        
Sbjct: 308  TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP------- 360

Query: 164  IGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
                   +TP+    T   E + T      + P E    + + P P+    P+     P+
Sbjct: 361  -------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPK 411

Query: 224  TQNPETLEDIQSSSLQQEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
               P T ++   ++ ++ AP      P   +E   +  + AP  P E S  +   P    
Sbjct: 412  EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 471

Query: 281  SVQP---------------PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQA 321
              +P               P         P  T KPA    T   EP      ET  +  
Sbjct: 472  PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTP 528

Query: 322  QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV 373
            ++ TP   PE++ P+  ++ AP  P    P  P E   +  E+  P  P      +P+E 
Sbjct: 529  KKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587

Query: 374  ------ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
                  E +PT  + P           +P G   T  L  P+ +         +A   + 
Sbjct: 588  APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 646

Query: 428  EVGTSLVHQEATTRLSGSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-- 477
            E  ++   + A T   G+      EP P       P  P+ +     +E  P   ++   
Sbjct: 647  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 706

Query: 478  -----TSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ 532
                 T+ + P    ++ P+PT  +  A  P T +E   +   + AP  TPE P      
Sbjct: 707  KELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------ 757

Query: 533  PPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PP  S ++  T          +P+  T E+   PT K     P +  VP        T  
Sbjct: 758  PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTK 809

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            TP   +      P +T        T   + TTE    T P+ T  +PK  + T    ++ 
Sbjct: 810  TPAATK------PEMT--------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK- 854

Query: 652  QTQHSHLTRATVQPLDLG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLP 701
             T  S +T  T Q           F IT    T + P        +TT      PE T  
Sbjct: 855  -TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 913

Query: 702  PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTT 761
            P D+  A +S  T    Q          KPT   K   +T++  T P        P P  
Sbjct: 914  PKDR--ATNSKATTPKPQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 961

Query: 762  ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             T     L  T+      +QT  R          E+ P  +    +E  T +  L
Sbjct: 962  MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1016



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 96/386 (24%), Positives = 138/386 (35%), Gaps = 38/386 (9%)

Query: 481 QSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
           QS E  + ++ +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + 
Sbjct: 218 QSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTT 277

Query: 539 LTQATVQPLDLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQD 596
           +  A   P +   T T  + T   E +PT  KE     PK+  P          PT  + 
Sbjct: 278 IKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKS 334

Query: 597 QAQHPVSPSVTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
               P  P+ T           P PTT  E   +TP + T  +PK P  T   P     +
Sbjct: 335 APTTPKEPAPTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPK 387

Query: 655 HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               T A  +P       TPK      P     TT   P       P + K  A  +  +
Sbjct: 388 EPAPT-APKKPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKS 436

Query: 715 QATVQPLDLELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
             T        T  + PTT  +PSPTT  E   T P +      P PTT    +    K 
Sbjct: 437 APTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKE 490

Query: 773 TAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
            AP   +      + T+   P T  EPA  +  ++   T  K LT     K + +T    
Sbjct: 491 PAPTTPKEPA--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKP 547

Query: 833 LCTCGDEMLSCIDLNPEQRLRQVPVP 858
             T  +E+       P     + P P
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAP 573



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 53/214 (24%), Positives = 83/214 (38%), Gaps = 14/214 (6%)

Query: 618 TPEPTTEVGH--STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT---RATVQPLDLGFTI 672
           TP+ +T   +  ST PK T   P +P  +LP P+   ++ + LT     TV+  +   T 
Sbjct: 142 TPDTSTTQHNKVSTSPKITTAKPINPRPSLP-PNSDTSKETSLTVNKETTVETKETTTTN 200

Query: 673 TPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPT 732
              S    E +T+   T          L P+ K  A+ +   + T +   L       PT
Sbjct: 201 KQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPT 260

Query: 733 TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTG 792
           T  +P+ TT +   +P    +   P    E   +T     T P+     T     T+   
Sbjct: 261 TPKEPASTTPK---EPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT-----TKEPA 312

Query: 793 PPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
           P T  EPA  +  +    T   A T P+E   +T
Sbjct: 313 PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTT 346



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 759  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 818

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 819  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 867


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 326

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 327 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 386

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 387 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 444

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 445 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 501

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 502 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 556

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 557 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 663

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 780

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 781 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 839

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 840 SAEPTPKALENSPKEPGVPTTKTPAATKPE 869



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 190/814 (23%), Positives = 276/814 (33%), Gaps = 176/814 (21%)

Query: 35  KEAQPLEWVK-DPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
           KE Q +E      L  TS  L  P P +  ++  P     A T P +P            
Sbjct: 267 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-----ALTTPKEP------------ 309

Query: 94  EMPAPPQE--STENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
             P  P+E  ST    P   T  SA   P EP    A         +P+E  P + K   
Sbjct: 310 -TPTTPKEPASTTPKEPTPTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTK--- 361

Query: 152 KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
            +PA               +TP+    T   E + T T    + P E    + + P P+ 
Sbjct: 362 -EPAP--------------TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 406

Query: 212 QVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSME 271
              P+     P+   P T ++          PA  P   E  P++ ++ AP  P + +  
Sbjct: 407 PKEPAP--TTPKEPTPTTPKE----------PA--PTTKEPAPTTPKEPAPTAPKKPAP- 451

Query: 272 SLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPE 331
             T P       P          P+ T        T  S PT   E +    ++    P+
Sbjct: 452 --TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 509

Query: 332 EVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE----SPREVESSPTQQETPGQPP 387
           E  P+ T++ AP  P  P      +  ++  P  P E    +P+E   + T++  P  P 
Sbjct: 510 EPSPTTTKEPAPTTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 565

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
           E    T                               P     T+      TT    +  
Sbjct: 566 EPAPTT-------------------------------PKETAPTTPKKLTPTTPEKLAPT 594

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
             E PA         P + EE  P      T+ + P P   E P+PT  +AAA  P T +
Sbjct: 595 TPEKPA---------PTTPEELAP------TTPEEPTPTTPEEPAPTTPKAAA--PNTPK 637

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG--FTITPESKTEVELSP 565
           E   +   + AP  TP+ P      P E +  T     P  L      TP+     EL+P
Sbjct: 638 EPAPTTPKEPAPT-TPKEP--APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 694

Query: 566 TMKETPTQP----PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
           T  + PT      P    P+     G    TP +     P  P+ T          TP+ 
Sbjct: 695 TTTKEPTSTTCDKPAPTTPK-----GTAPTTPKEPAPTTPKEPAPT----------TPKG 739

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           T       P   T   P  P+   P   +  T  +    A   P +   T TPK      
Sbjct: 740 TAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTT 797

Query: 682 PSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PS 738
           P     TT   PPP   EV+ P                        T T +PTT  K P 
Sbjct: 798 PKKPAPTTPETPPPTTSEVSTP------------------------TTTKEPTTIHKSPD 833

Query: 739 PTTEETSTQPPDLGLAIIPE----PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP 794
            +T E S +P    L   P+    PTT+T  +T  E TT  +    +   R+  E T   
Sbjct: 834 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 893

Query: 795 TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
            ++   +++   +E  T++K +TA      ST+T
Sbjct: 894 PKM--TKETATTTEKTTESK-ITATTTQVTSTTT 924



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 186/835 (22%), Positives = 281/835 (33%), Gaps = 148/835 (17%)

Query: 53   PLGPPEPWSSHSSH-FPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLD 111
            P  P EP S+      P     APT P +P       P+ +   P  P+E          
Sbjct: 311  PTTPKEPASTTPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT----- 359

Query: 112  TWDSAGELPLEPEQFLASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEI 163
            T + A   P EP      +       S    P+E  P +PKK      K+PA        
Sbjct: 360  TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP------- 412

Query: 164  IGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
                   +TP+    T   E + T      + P E    + + P P+    P+     P+
Sbjct: 413  -------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPK 463

Query: 224  TQNPETLEDIQSSSLQQEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
               P T ++   ++ ++ AP      P   +E   +  + AP  P E S  +   P    
Sbjct: 464  EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 523

Query: 281  SVQP---------------PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQA 321
              +P               P         P  T KPA    T   EP      ET  +  
Sbjct: 524  PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTP 580

Query: 322  QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV 373
            ++ TP   PE++ P+  ++ AP  P    P  P E   +  E+  P  P      +P+E 
Sbjct: 581  KKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639

Query: 374  ------ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
                  E +PT  + P           +P G   T  L  P+ +         +A   + 
Sbjct: 640  APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 698

Query: 428  EVGTSLVHQEATTRLSGSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-- 477
            E  ++   + A T   G+      EP P       P  P+ +     +E  P   ++   
Sbjct: 699  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758

Query: 478  -----TSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ 532
                 T+ + P    ++ P+PT  +  A  P T +E   +   + AP  TPE P      
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------ 809

Query: 533  PPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PP  S ++  T          +P+  T E+   PT K     P +  VP        T  
Sbjct: 810  PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTK 861

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            TP   +      P +T        T   + TTE    T P+ T  +PK  + T    ++ 
Sbjct: 862  TPAATK------PEMT--------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK- 906

Query: 652  QTQHSHLTRATVQPLDLG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLP 701
             T  S +T  T Q           F IT    T + P        +TT      PE T  
Sbjct: 907  -TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 965

Query: 702  PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTT 761
            P D+  A +S  T    Q          KPT   K   +T++  T P        P P  
Sbjct: 966  PKDR--ATNSKATTPKPQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1013

Query: 762  ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             T     L  T+      +QT  R          E+ P  +    +E  T +  L
Sbjct: 1014 MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1068



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 128/617 (20%), Positives = 219/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 124

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 125 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 171

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 172 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 231

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 232 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 338

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 339 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 395

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 396 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 447

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 448 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 497

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT    +    K  AP   +  
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 552 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 609 PTTPEEPTPTTPEEPAP 625



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 811  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 870

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 871  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 919


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score =  106 bits (264), Expect = 2e-22
 Identities = 159/630 (25%), Positives = 219/630 (34%), Gaps = 87/630 (13%)

Query: 251 EEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE----- 305
           +E  S  +  A  L P S + +   P  E + + P         P    +PA        
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPT 367

Query: 306 -VTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP--PVPPMEHE-LSISEQQ 361
             TI S PT   E +    ++    P+E  P+ T++ AP  P  P P    E    + + 
Sbjct: 368 PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKS 427

Query: 362 QPVQPSE------------SPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPS 409
            P  P E            +P+E   +  ++ TP  P E    T  P     T    +P+
Sbjct: 428 APTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPA--PTTPKEPAPT 485

Query: 410 VSVK-------------PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
              K             P +   T   EPS    T+      TT  S      EP     
Sbjct: 486 APKKPAPTTPKEPAPTTPKEPAPTTTKEPSP---TTPKEPAPTTTKSAPTTTKEPAPTTT 542

Query: 457 GGPPLLPESSEEAGPLAVQQ--ETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLT 514
              P  P   +E  P   ++   T+ + P P   + P+PT  +  A  P T +E   + T
Sbjct: 543 KSAPTTP---KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPA--PTTPKEPAPTTT 597

Query: 515 HQEAPAQTPEFPNVVVAQ---PPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + AP  TP+ P     +   P     LT  T + L       P   T  EL+PT  E P
Sbjct: 598 KKPAPT-TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656

Query: 572 T----QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTT--EV 625
           T    + P    P+         P P   +   P +P              P PTT  E 
Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPK------------EPAPTTPKET 704

Query: 626 GHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST 684
             +TP      + K P  T P  P   +   +     T    D     TPK      P  
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764

Query: 685 ALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKP--TTEVKPSPT 740
              TT   P P  P+ T P + K  A     T     P +L  T T  P  TT  KP+PT
Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKGPTSTTSDKPAPT 821

Query: 741 TEE----TSTQPPDLGLAIIPEPTT-ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
           T +    T+ + P       P PTT ET   T  E +T        T+H+S  E T P  
Sbjct: 822 TPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDEST-PEL 880

Query: 796 ELEPAQDSLVQSES-----YTQNKALTAPE 820
             EP   +L  S        T+  A T PE
Sbjct: 881 SAEPTPKALENSPKEPGVPTTKTPAATKPE 910



 Score = 99.8 bits (247), Expect = 2e-20
 Identities = 190/814 (23%), Positives = 276/814 (33%), Gaps = 176/814 (21%)

Query: 35  KEAQPLEWVK-DPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASS 93
           KE Q +E      L  TS  L  P P +  ++  P     A T P +P            
Sbjct: 308 KETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGP-----ALTTPKEP------------ 350

Query: 94  EMPAPPQE--STENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
             P  P+E  ST    P   T  SA   P EP    A         +P+E  P + K   
Sbjct: 351 -TPTTPKEPASTTPKEPTPTTIKSAPTTPKEP----APTTTKSAPTTPKEPAPTTTK--- 402

Query: 152 KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSE 211
            +PA               +TP+    T   E + T T    + P E    + + P P+ 
Sbjct: 403 -EPAP--------------TTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTT 447

Query: 212 QVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSME 271
              P+     P+   P T ++          PA  P   E  P++ ++ AP  P + +  
Sbjct: 448 PKEPAP--TTPKEPTPTTPKE----------PA--PTTKEPAPTTPKEPAPTAPKKPAP- 492

Query: 272 SLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPE 331
             T P       P          P+ T        T  S PT   E +    ++    P+
Sbjct: 493 --TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK 550

Query: 332 EVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE----SPREVESSPTQQETPGQPP 387
           E  P+ T++ AP  P  P      +  ++  P  P E    +P+E   + T++  P  P 
Sbjct: 551 EPSPTTTKEPAPTTPKEPAP----TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPK 606

Query: 388 EHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGN 447
           E    T                               P     T+      TT    +  
Sbjct: 607 EPAPTT-------------------------------PKETAPTTPKKLTPTTPEKLAPT 635

Query: 448 DVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAE 507
             E PA         P + EE  P      T+ + P P   E P+PT  +AAA  P T +
Sbjct: 636 TPEKPA---------PTTPEELAP------TTPEEPTPTTPEEPAPTTPKAAA--PNTPK 678

Query: 508 EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLG--FTITPESKTEVELSP 565
           E   +   + AP  TP+ P      P E +  T     P  L      TP+     EL+P
Sbjct: 679 EPAPTTPKEPAPT-TPKEP--APTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAP 735

Query: 566 TMKETPTQP----PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
           T  + PT      P    P+     G    TP +     P  P+ T          TP+ 
Sbjct: 736 TTTKEPTSTTCDKPAPTTPK-----GTAPTTPKEPAPTTPKEPAPT----------TPKG 780

Query: 622 TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE 681
           T       P   T   P  P+   P   +  T  +    A   P +   T TPK      
Sbjct: 781 TAPTTLKEPAPTTPKKPA-PKELAPTTTKGPTSTTSDKPAPTTPKETAPT-TPKEPAPTT 838

Query: 682 PSTALMTT--APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVK-PS 738
           P     TT   PPP   EV+ P                        T T +PTT  K P 
Sbjct: 839 PKKPAPTTPETPPPTTSEVSTP------------------------TTTKEPTTIHKSPD 874

Query: 739 PTTEETSTQPPDLGLAIIPE----PTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP 794
            +T E S +P    L   P+    PTT+T  +T  E TT  +    +   R+  E T   
Sbjct: 875 ESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAA 934

Query: 795 TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
            ++   +++   +E  T++K +TA      ST+T
Sbjct: 935 PKM--TKETATTTEKTTESK-ITATTTQVTSTTT 965



 Score = 99.4 bits (246), Expect = 3e-20
 Identities = 186/835 (22%), Positives = 281/835 (33%), Gaps = 148/835 (17%)

Query: 53   PLGPPEPWSSHSSH-FPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLD 111
            P  P EP S+      P     APT P +P       P+ +   P  P+E          
Sbjct: 352  PTTPKEPASTTPKEPTPTTIKSAPTTPKEP------APTTTKSAPTTPKEPAPTT----- 400

Query: 112  TWDSAGELPLEPEQFLASQQDLKDKLS----PQERLPVSPKK----LKKDPAQRWSLAEI 163
            T + A   P EP      +       S    P+E  P +PKK      K+PA        
Sbjct: 401  TKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAP------- 453

Query: 164  IGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
                   +TP+    T   E + T      + P E    + + P P+    P+     P+
Sbjct: 454  -------TTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAP--TTPK 504

Query: 224  TQNPETLEDIQSSSLQQEAPA---QLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
               P T ++   ++ ++ AP      P   +E   +  + AP  P E S  +   P    
Sbjct: 505  EPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTT 564

Query: 281  SVQP---------------PGEDQAYYHLPNITVKPADVEVTITSEPT----NETESSQA 321
              +P               P         P  T KPA    T   EP      ET  +  
Sbjct: 565  PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAP---TTPKEPAPTTPKETAPTTP 621

Query: 322  QQETPIQFPEEVEPSATQQEAPIEP----PVPPMEHELSISEQQQPVQPS----ESPREV 373
            ++ TP   PE++ P+  ++ AP  P    P  P E   +  E+  P  P      +P+E 
Sbjct: 622  KKLTPTT-PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680

Query: 374  ------ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA 427
                  E +PT  + P           +P G   T  L  P+ +         +A   + 
Sbjct: 681  APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTT-LKEPAPTTPKKPAPKELAPTTTK 739

Query: 428  EVGTSLVHQEATTRLSGSGNDV--EP-PAIQHGGPPLLPESS-----EEAGPLAVQQE-- 477
            E  ++   + A T   G+      EP P       P  P+ +     +E  P   ++   
Sbjct: 740  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799

Query: 478  -----TSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQ 532
                 T+ + P    ++ P+PT  +  A  P T +E   +   + AP  TPE P      
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETA--PTTPKEPAPTTPKKPAPT-TPETP------ 850

Query: 533  PPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PP  S ++  T          +P+  T E+   PT K     P +  VP        T  
Sbjct: 851  PPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVP--------TTK 902

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            TP   +      P +T        T   + TTE    T P+ T  +PK  + T    ++ 
Sbjct: 903  TPAATK------PEMT--------TTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK- 947

Query: 652  QTQHSHLTRATVQPLDLG------FTITPKSMTEVEPSTAL----MTTAPPPGHPEVTLP 701
             T  S +T  T Q           F IT    T + P        +TT      PE T  
Sbjct: 948  -TTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNKPEETAK 1006

Query: 702  PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTT 761
            P D+  A +S  T    Q          KPT   K   +T++  T P        P P  
Sbjct: 1007 PKDR--ATNSKATTPKPQ----------KPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRK 1054

Query: 762  ETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL 816
             T     L  T+      +QT  R          E+ P  +    +E  T +  L
Sbjct: 1055 MTSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGETPHMLL 1109



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 128/617 (20%), Positives = 219/617 (35%), Gaps = 72/617 (11%)

Query: 254 PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
           P+S      A PP  + +++       S +PP + +    + +  +     E +++    
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKR-SPKPPNKKKTKKVIESEEITE---EHSVSENQE 165

Query: 314 NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
           + + SS +   + I+  +  + SA  +E         ++ +L + + ++    + + ++ 
Sbjct: 166 SSSSSSSSSSSSTIRKIKSSKNSAANRE---------LQKKLKVKDNKK----NRTKKKP 212

Query: 374 ESSPTQQETPGQPPEHHEVTVSPPGHHQTHH---LASPSVSV-KPPDVQLTIAAEPSAEV 429
              P   +  G   ++ +  V+ P    T H     SP ++  KP + + ++        
Sbjct: 213 TPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSK 272

Query: 430 GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNE 489
            TSL   + TT             ++        + +   G          QS E  + +
Sbjct: 273 ETSLTVNKETT-------------VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319

Query: 490 NPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
           + +PT +  A   P  +T  +G +  T +E    TP+ P     + P  + +  A   P 
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPK 379

Query: 548 DLGFTITPESKTEV-ELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS 605
           +   T T  + T   E +PT  KE     PK+  P          PT  +     P  P+
Sbjct: 380 EPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPA---PTTTKSAPTTPKEPA 436

Query: 606 VTVQLLDLGLTITPEPTT--EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            T           P PTT  E   +TP + T  +PK P  T   P     +    T A  
Sbjct: 437 PTTPK-------KPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPT-APK 488

Query: 664 QPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDL 723
           +P       TPK      P     TT   P       P + K  A  +  +  T      
Sbjct: 489 KPAPT----TPKEPAPTTPKEPAPTTTKEPS------PTTPKEPAPTTTKSAPTTTKEPA 538

Query: 724 ELTITTKPTTEVKPSPTT--EETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQ 781
             T  + PTT  +PSPTT  E   T P +      P PTT    +    K  AP   +  
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKE------PAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 782 TLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEML 841
               + T+   P T  EPA  +  ++   T  K LT     K + +T      T  +E+ 
Sbjct: 593 A--PTTTKKPAPTTPKEPAPTTPKETAPTTPKK-LTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 842 SCIDLNPEQRLRQVPVP 858
                 P     + P P
Sbjct: 650 PTTPEEPTPTTPEEPAP 666



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 4/113 (3%)

Query: 1209 PAPREVEQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQV 1268
            P   EV  P T + P  +  +   + P  + E         P   G P+T +PA   P++
Sbjct: 852  PTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEM 911

Query: 1269 RDRWKDLTHAISILESAKARVTNTKTSKPIVHARKKYRFHKTRSHVTHRTPKV 1321
                KD T    +  + +      K +K      +K     T S +T  T +V
Sbjct: 912  TTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEK----TTESKITATTTQV 960


>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
            sapiens]
          Length = 5537

 Score = 94.7 bits (234), Expect = 6e-19
 Identities = 188/794 (23%), Positives = 270/794 (34%), Gaps = 125/794 (15%)

Query: 52   NPLGPPEPWSSHSSHFP---RESPHAPTLPADPW-DFDHLG-PSASSEMPAPPQESTENL 106
            +PL PP P  S +S  P   R SP    LPA P  +  HL  P   S +  PP+ES  + 
Sbjct: 447  SPLSPP-PEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPLSPPPEESPLSP 505

Query: 107  VPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQ-ERLPVSPKKLKKDPAQRWSLAEIIG 165
             P    +    E PL P +       L+  LSP  E  P+SP   ++ P           
Sbjct: 506  PPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPP-FEESP----------- 553

Query: 166  IIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQ 225
                LS P  +               P S PPE    S  P        P +  + P  +
Sbjct: 554  ----LSPPPEE--------------LPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPE 595

Query: 226  NPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPP 285
                    + S L            EE P S   EA  L P      ++ P  E  + PP
Sbjct: 596  ASRLFPPFEESPLSPPP--------EESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPP 647

Query: 286  GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPI 344
             E      LP ++      E +  S P  E+ +S   + + +  P E  P S   +++P 
Sbjct: 648  PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707

Query: 345  EPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP-PEHHEVTVSPPGHHQTH 403
             P  PP +  +S+  ++ P+ P   P E +  P  +     P PE   ++  P   H + 
Sbjct: 708  SP--PPEDSLMSLPLEESPLLP--LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763

Query: 404  HLASPSVSVKPPDVQLTIAAE-----PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG 458
                P +S +P +  L    E     P AE G  L  Q     LS    +          
Sbjct: 764  QAEEPHLSPQPEEPCLCAVPEEPHLSPQAE-GPHLSPQPEELHLSPQTEE---------- 812

Query: 459  PPLLPESSEEA-GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQE 517
            P L P   E    P   +   S QS EP  +  P  +      E P  +   E      E
Sbjct: 813  PHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKP---PE 869

Query: 518  APAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKK 577
             P Q P    + +  PP    L+    +P             E  LSP  +E P  P  +
Sbjct: 870  EPGQCPAPEELPLFPPPGEPSLSPLLGEP-------ALSEPGEPPLSPLPEELPLSPSGE 922

Query: 578  VVPQLRVYQGVTNPTPGQDQAQHPVSPSVTV----QLLDLGLTITP-----EPTTEVGHS 628
              P L       +P P       P+SP +T      L  LG    P     +   E   +
Sbjct: 923  --PSLSPQLMPPDPLP------PPLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLA 974

Query: 629  TPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP------ 682
             P   T +SP  PE     P+ V           + P   G  + P S   +EP      
Sbjct: 975  APILETPISPP-PEANCTDPEPVPPM--------ILPPSPGSPVGPASPILMEPLPPQCS 1025

Query: 683  ----STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPS 738
                 + +   +PP       LP S                  +L    T K +    P+
Sbjct: 1026 PLLQHSLVPQNSPPSQCSPPALPLSVPSPLSPIGKVVGVSDEAELHEMETEKVSEPECPA 1085

Query: 739  PTTEETSTQPPDLGLAIIPEPT--------TETGHSTA-LEKTTAP--RPDRVQTLHRSL 787
                 TS  P  +G    P P+        +  G  TA L+   AP  +P+  QT     
Sbjct: 1086 LEPSATSPLPSPMGDLSCPAPSPAPALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLA 1145

Query: 788  TEVTGPPTELEPAQ 801
            +E+ G P  L+P +
Sbjct: 1146 SELKGSPVLLDPEE 1159



 Score = 89.7 bits (221), Expect = 2e-17
 Identities = 152/613 (24%), Positives = 233/613 (38%), Gaps = 93/613 (15%)

Query: 183 EYSSTDTPYPGSL-------PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
           E   T T  P +L       P    V S +P  P    GP Q   +P  +    LE    
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEP----GPLQCEAKPLGKAGVQLEPQLE 431

Query: 236 SSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS-VQPPGEDQAYYHL 294
           + L +E P   P           +E+P  PP    ES T P  E S + PP E+     L
Sbjct: 432 APLNEEMPLLPPP----------EESPLSPPPE--ESPTSPPPEASRLSPPPEELPASPL 479

Query: 295 PNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-----EPPVP 349
           P         E    S P  E+  S   +E+P+  P E  P +  +E+P+      PP P
Sbjct: 480 P---------EALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSP 530

Query: 350 PMEHELSISEQQQPVQP--SESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +E  LS   +  P+ P   ESP     SP  +E P  PP        PP   ++     
Sbjct: 531 ALETPLSPPPEASPLSPPFEESP----LSPPPEELPTSPPPEASRLSPPP--EESPMSPP 584

Query: 408 PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
           P  S   P  + +    P  E   S   +E+        + + PP       P+ P   E
Sbjct: 585 PEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPP---EDSPMSPPPEE 641

Query: 468 EAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA------EEGESSLTHQEAPAQ 521
              P++   E S  SP P+ +    P ++   +  P+ +      E    S   +++P  
Sbjct: 642 --SPMSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTS 699

Query: 522 TPEFPNVVVAQPPEHS----HLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKK 577
            P   +   + PPE S     L ++ + PL     + P S+    LSP  +E P   P+ 
Sbjct: 700 PPP-EDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGP-HLSPRPEE-PHLSPRP 756

Query: 578 VVPQLRVYQGVTNPTPGQDQ---AQHPVSPSVTVQLLDLGLTITPE-----PTTEVGHST 629
             P L       + +P  ++      P  P ++ Q     L+  PE     P TE  H +
Sbjct: 757 EEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLS 816

Query: 630 P-PKRTIVSPKHPEVTL-PHPDQ----VQTQHSHLTRATVQPLDLGFTITPKSMTEVE-- 681
           P P+   +SP+  E  L P  ++     + + SHL+    +P      ++P+     E  
Sbjct: 817 PVPEEPCLSPQPEESHLSPQSEEPCLSPRPEESHLSPELEKP-----PLSPRPEKPPEEP 871

Query: 682 ---PSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPS 738
              P+   +   PPPG P  +L P   G+   S   +  + PL  EL ++  P+ E   S
Sbjct: 872 GQCPAPEELPLFPPPGEP--SLSPL-LGEPALSEPGEPPLSPLPEELPLS--PSGEPSLS 926

Query: 739 PTTEETSTQPPDL 751
           P        PP L
Sbjct: 927 PQLMPPDPLPPPL 939



 Score = 67.8 bits (164), Expect = 8e-11
 Identities = 99/427 (23%), Positives = 149/427 (34%), Gaps = 78/427 (18%)

Query: 356 SISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTV--SPPGHHQTHHLASPSVSVK 413
           S++EQ  PV    SP      P   +TP   P+   V     P G H T      S+  K
Sbjct: 360 SVAEQHTPVCSRFSP------PEPGDTPTDEPDALYVACQGQPKGGHVT------SMQPK 407

Query: 414 PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA 473
            P   L   A+P  + G  L  Q            +E P  +    PLLP   E   PL+
Sbjct: 408 EPG-PLQCEAKPLGKAGVQLEPQ------------LEAPLNEE--MPLLPPPEE--SPLS 450

Query: 474 VQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP--EFPNVVVA 531
              E S  SP P  +    P ++  A+  P+       S   +E+P   P  E P   ++
Sbjct: 451 PPPEESPTSPPPEASRLSPPPEELPASPLPEAL---HLSRPLEESPLSPPPEESP---LS 504

Query: 532 QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
            PPE S  +     PL       P    E  LSP  + +P  PP +  P         +P
Sbjct: 505 PPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESP--------LSP 556

Query: 592 TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQV 651
            P     + P SP      L                S PP+ + +SP   E  +  P + 
Sbjct: 557 PP----EELPTSPPPEASRL----------------SPPPEESPMSPPPEESPMSPPPEA 596

Query: 652 QTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHS 711
                    + + P        P   + + P       +PPP    ++ PP +   +   
Sbjct: 597 SRLFPPFEESPLSP--------PPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648

Query: 712 HLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEK 771
            +++ +  P+   L   + P  E   SP  EE+ T PP     + P P          + 
Sbjct: 649 EVSRLSPLPVVSRL---SPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDS 705

Query: 772 TTAPRPD 778
             +P P+
Sbjct: 706 PASPPPE 712



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 139/674 (20%), Positives = 216/674 (32%), Gaps = 109/674 (16%)

Query: 87   LGPSASSEMPAPPQESTENLVPFLDTWDSAG-ELPLEPEQFLASQQDLKDKLSPQ---ER 142
            LGP     MP  P      LV  L      G +  L P Q    QQ     L PQ    +
Sbjct: 3769 LGPKPQGLMP--PSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQ 3826

Query: 143  LPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVK 202
            + ++  ++   P        ++G   +L T Q Q+Q  Q++   +       L   L   
Sbjct: 3827 VLMTQSRVLSSPQLAQQGQGLMG--HRLVTAQQQQQQQQHQQQGSMAGL-SHLQQSLMSH 3883

Query: 203  SDEPPGPSEQVGP---------------------SQFHLEPETQNPETLEDIQSSSLQQE 241
            S +P   ++ +G                       Q   + + Q  +  +  Q   LQQ+
Sbjct: 3884 SGQPKLSAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQ 3943

Query: 242  APAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHL--PNITV 299
               QL Q  ++     QQ+      +   + + L N   ++  P + Q       P +  
Sbjct: 3944 QQQQLQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPA 4003

Query: 300  KPAD-VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-------EPPVPPM 351
            KP           PT      +     P    E  E  +T Q  P+            P 
Sbjct: 4004 KPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQGGPLAIGTTPESMATEPG 4063

Query: 352  EHELSISEQQQPV----QPSESPREVESSPTQQETPGQPPEHHEV--TVSPPGHHQTHHL 405
            E + S+S   Q +    QP   P  ++  P  +  PGQ  +   +  T     H Q    
Sbjct: 4064 EVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLR-LPGQQQQQVSLLHTAGGGSHGQLGSG 4122

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND-VEPPAIQHGGP----- 459
            +S   S  P      + A+PS  +G        T  L G     +E P   + GP     
Sbjct: 4123 SSSEASSVP-----HLLAQPSVSLGDQ--PGSMTQNLLGPQQPMLERPMQNNTGPQPPKP 4175

Query: 460  -PLLPESS--------EEAGPLAVQQETSFQSPEPINNENPSPTQQEAA---AEHPQTAE 507
             P+L               G L  Q +        + + +P   QQ  A       Q ++
Sbjct: 4176 GPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLMQRQLQQSQ 4235

Query: 508  EGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM 567
                +  +QE   QT     ++  QP         T    +LG    P+    +   P  
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGA 4295

Query: 568  KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH 627
              T         P L    G  +PTP     Q P  PS   QL        P P++++  
Sbjct: 4296 LSTG--------PVL----GPVHPTPPPSSPQEPKRPS---QL--------PSPSSQL-- 4330

Query: 628  STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               P    + P HP    P    ++     ++ A  Q  D   T+  K +   +P   L 
Sbjct: 4331 ---PTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLAD---TLFSKGLGPWDPPDNLA 4384

Query: 688  TTAPP------PGH 695
             T  P      PGH
Sbjct: 4385 ETQKPEQSSLVPGH 4398



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 189/851 (22%), Positives = 268/851 (31%), Gaps = 149/851 (17%)

Query: 37   AQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPH--APTLPA--DPWDFDHLGPSAS 92
            A PLE    P   T+ P  PP P  + +   P + P   A + P    P +F    P   
Sbjct: 2182 AYPLE----PRFPTAPPTYPPYPSPTGA---PAQPPMLGASSRPGAGQPGEFHTTPPGTP 2234

Query: 93   SEMPAPPQESTENLVPFLDTW----------DSAGELPLEPEQFLASQQDLKDKLSPQER 142
               P+ P    +   P LD              A E  L P  F  S++ L+ K   +E 
Sbjct: 2235 RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVK---KEE 2291

Query: 143  LPVS-----PKKLK--KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSL 195
            L  S     P  L     P+    L  +     +L TP   K  L    S  +   PG  
Sbjct: 2292 LGASSPSYGPPNLGFVDSPSSGTHLGGL-----ELKTPDVFKAPLTPRASQVEPQSPG-- 2344

Query: 196  PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPS 255
               L ++  EPP P++ + PS          P +  DI       +  AQ P     +P 
Sbjct: 2345 ---LGLRPQEPP-PAQALAPS----------PPSHPDIFRPGSYTDPYAQPPLTPRPQPP 2390

Query: 256  SMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNE 315
               +   ALPP S      LP+   S  P            +T +P   E    S  T  
Sbjct: 2391 P-PESCCALPPRS------LPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPR 2443

Query: 316  TESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS----------------- 358
             +S       P +      P +    AP+  P  P   E++                   
Sbjct: 2444 FQSPDPYSRPPSR------PQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAA 2497

Query: 359  -------EQQQPVQPSESPREVES----------SPTQQETP---GQPPEHHEVTVS--P 396
                   E    V   + P  V S          SP +   P   G+P     V     P
Sbjct: 2498 LPAGPAGELHAKVPSGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLP 2557

Query: 397  PGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH 456
            P H    H        KP     T+A       G+ L     +T  S   + + PP++  
Sbjct: 2558 PPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVL- 2616

Query: 457  GGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHPQTAEEGESSL-- 513
              PP  P+ S         Q +   SP E   +         A AE P T + G S L  
Sbjct: 2617 --PPPAPDGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQ 2674

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVE-LSPTMK---- 568
            T  E   Q      +++ Q  + + L Q           + P      E  SP  +    
Sbjct: 2675 TELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSR 2734

Query: 569  -ETP---TQPPKKVV--PQLRVYQGVTNP--TPGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             +TP   TQ    +V  P  ++   +  P   P  D+   P  P  T   +D+       
Sbjct: 2735 GQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFPSDDRLSRP-PPPATPSSMDV------N 2787

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQ--PLDLGFTITP---- 674
                VG S    +   +P    + L    Q   Q    T AT     +   F  TP    
Sbjct: 2788 SRQLVGGSQAFYQR--APYPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPEL 2845

Query: 675  KSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTE 734
                   P   + T  P PG P     P   G AQ   L     + L    T        
Sbjct: 2846 GRQALGSPLAGISTRLPGPGEP----VPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPP 2901

Query: 735  VKPS--PTTEETSTQPPD--LGLAI--IPEPTTETGHSTALEKTTAPRP-DRVQTLHRSL 787
             +P   P +E+     P+   GLA+  +P        +  L  +  P P  +  TL   L
Sbjct: 2902 QRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLPTGL 2961

Query: 788  TEVTGPPTELE 798
              V  PP+  E
Sbjct: 2962 ELVNRPPSSTE 2972



 Score = 40.0 bits (92), Expect = 0.019
 Identities = 70/286 (24%), Positives = 100/286 (34%), Gaps = 36/286 (12%)

Query: 503  PQTAEEGESSLTHQEAPAQT--PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            PQ   +  S      APA    P FP      PP  S  T A  QP  LG +  P +   
Sbjct: 2165 PQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP-TGAPAQPPMLGASSRPGAGQP 2223

Query: 561  VELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             E   T   TP   P    P L+         P  D    P SP V        L ++P 
Sbjct: 2224 GEFHTTPPGTPRHQPSTPDPFLKPR------CPSLDNLAVPESPGVGGGKASEPL-LSPP 2276

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS--HLTRATVQPLDL-GFTITPKSM 677
            P  E   +   K+  +    P    P+   V +  S  HL    ++  D+    +TP++ 
Sbjct: 2277 PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRA- 2335

Query: 678  TEVEPSTALMTTAP------------PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL 725
            ++VEP +  +   P            PP HP++  P S         LT     P     
Sbjct: 2336 SQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395

Query: 726  ------TITTKPTTEVKPSPTTEETSTQP----PDLGLAIIPEPTT 761
                  ++ + P + V  SP ++ +S  P    P    A  P P T
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVT 2441



 Score = 39.3 bits (90), Expect = 0.032
 Identities = 114/611 (18%), Positives = 208/611 (34%), Gaps = 112/611 (18%)

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQ----EAPALPPESSMESLTLP 276
            + + Q  +  +  Q S++   +P+Q P+LL + P  +      + P  PP      L L 
Sbjct: 3599 QQQQQQQQQQQQQQHSAVLALSPSQSPRLLTKLPGQLLPGHGLQPPQGPPGGQAGGLRLT 3658

Query: 277  NHEVSV--QPPG--------EDQAYYHL---------------PNITVKPADVEVTITSE 311
               +++  QP G        + Q   H                 N+ ++    +  +  E
Sbjct: 3659 PGGMALPGQPGGPFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSLGPDSRLLQE 3718

Query: 312  P-----------TNETESSQAQQETPIQFPEEVEPSATQQEAP-------IEPP----VP 349
                          + +  Q QQ+       +V     QQ+ P       + P     +P
Sbjct: 3719 RQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQALGPKPQGLMP 3778

Query: 350  PMEHELSISEQQQPVQPSESPR----EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHL 405
            P  H+  + +Q  P QP + P+      + +  QQ+ PG         + P G H+   +
Sbjct: 3779 PSSHQGLLVQQLSP-QPPQGPQGMLGPAQVAVLQQQHPG--------ALGPQGPHRQVLM 3829

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSG---NDVEPPAIQHGGPPLL 462
                V   P   Q          V      Q+   +  GS    + ++   + H G P L
Sbjct: 3830 TQSRVLSSPQLAQQGQGLMGHRLVTAQQQQQQQQHQQQGSMAGLSHLQQSLMSHSGQPKL 3889

Query: 463  PESSEEAGPL-AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQ 521
              S++  G L  +QQ+   Q  + +  +     QQ+   +  Q  ++ +     Q+   Q
Sbjct: 3890 --SAQPMGSLQQLQQQQQLQQQQQLQQQQQQQLQQQQQLQQQQLQQQQQQQQLQQQQQQQ 3947

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGF------TITP--ESKTEVELSPTMKETPTQ 573
              +    +  Q  +     Q   Q   +G        ++P  + + +V L P M   P Q
Sbjct: 3948 LQQQQQQLQQQQQQQQQQFQQQQQQQQMGLLNQSRTLLSPQQQQQQQVALGPGMPAKPLQ 4007

Query: 574  ---PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH--- 627
                P  + P L +            + Q+ V P+V+ +        T  P+T  G    
Sbjct: 4008 HFSSPGALGPTLLL----------TGKEQNTVDPAVSSE-------ATEGPSTHQGGPLA 4050

Query: 628  -STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP--KSMTEVEPST 684
              T P+     P   + +L    Q+      L +   QP      + P  +   + +   
Sbjct: 4051 IGTTPESMATEPGEVKPSLSGDSQLL-----LVQPQPQPQPSSLQLQPPLRLPGQQQQQV 4105

Query: 685  ALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK---PTTEVKPSPTT 741
            +L+ TA    H ++    S +  +    L Q +V   D   ++T     P   +   P  
Sbjct: 4106 SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQ 4165

Query: 742  EETSTQPPDLG 752
              T  QPP  G
Sbjct: 4166 NNTGPQPPKPG 4176



 Score = 33.5 bits (75), Expect = 1.7
 Identities = 120/551 (21%), Positives = 190/551 (34%), Gaps = 124/551 (22%)

Query: 114  DSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTP 173
            D+A   PL P+         K      +RL  S KKL+K+   R S A +  + ++LS  
Sbjct: 4511 DAAARKPLTPKP--------KRVQKASDRLVSSRKKLRKEDGVRASEALLKQLKQELSLL 4562

Query: 174  QSQKQTLQNEYSSTDTPYPGSLP----PELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
               +  +   +S    P+    P     +LR        P+     SQ   +    NP T
Sbjct: 4563 PLTEPAITANFSLF-APFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKNNLSNPPT 4621

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPP---- 285
                         P+ LP      P S+QQ+         M +   P+ E+   P     
Sbjct: 4622 ------------PPSSLPPT---PPPSVQQK---------MVNGVTPSEELGEHPKDAAS 4657

Query: 286  GEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQ-----Q 340
              D          VK  D+   + + P N+TE  + + +     P+ + P+++      +
Sbjct: 4658 ARDSERALRDTSEVKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESILGE 4717

Query: 341  EAPIEP---------------PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQ 385
            EAP  P               PV P+    SI     PV P   P          E PG+
Sbjct: 4718 EAPRFPHLGSGRWEQEDRALSPVIPLIPRASI-----PVFPDTKP----YGALGLEVPGK 4768

Query: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL--VHQEATTRLS 443
             P    VT    G           VS     V LT++A  +  +   +  V +  + ++ 
Sbjct: 4769 LP----VTTWEKG-------KGSEVS-----VMLTVSAAAAKNLNGVMVAVAELLSMKIP 4812

Query: 444  GSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHP 503
             S   + P +    G    P+  E  GP   ++    +SP+      P   +Q  A    
Sbjct: 4813 NSYEVLFPESPARAGTE--PKKGEAEGPGGKEKGLEGKSPD----TGPDWLKQFDAVLPG 4866

Query: 504  QTAEEGES--SLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
             T +      SL  QE+PA  P         P +HS+     V  LD+     P  +   
Sbjct: 4867 YTLKSQLDILSLLKQESPAPEP---------PTQHSY--TYNVSNLDVRQLSAPPPEEPS 4915

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
                 +  +P  PP + + +L          P +  A+ PV PS       L L  +PE 
Sbjct: 4916 PPPSPLAPSPASPPTEPLVEL----------PTEPLAEPPV-PS------PLPLASSPES 4958

Query: 622  TTEVGHSTPPK 632
                  + PP+
Sbjct: 4959 ARPKPRARPPE 4969



 Score = 32.0 bits (71), Expect = 5.0
 Identities = 40/160 (25%), Positives = 60/160 (37%), Gaps = 7/160 (4%)

Query: 45   DPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            D L L       PEP + HS  +   +     L A P   +   P  S   P+P    TE
Sbjct: 4874 DILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPP--PEEPSPPPSPLAPSPASPPTE 4931

Query: 105  NLVPFLDTWDSAGELPLEPEQFLASQQDLKDK---LSPQERLPVSPKKLKKDPAQRWSLA 161
             LV  L T   A      P    +S +  + K     P+E     P +LKK    RW   
Sbjct: 4932 PLVE-LPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWKGVRWKRL 4990

Query: 162  EIIGIIRQLSTPQSQKQTLQNEYSSTDTPY-PGSLPPELR 200
             ++  I++ S  Q  ++ +        T   P  +P ++R
Sbjct: 4991 RLLLTIQKGSGRQEDEREVAEFMEQLGTALRPDKVPRDMR 5030



 Score = 31.2 bits (69), Expect = 8.6
 Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 13/145 (8%)

Query: 234  QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV-QPPGEDQAYY 292
            +   L+ ++P   P  L++  + +    P    +S ++ L+L   E    +PP +    Y
Sbjct: 4841 KEKGLEGKSPDTGPDWLKQFDAVL----PGYTLKSQLDILSLLKQESPAPEPPTQHSYTY 4896

Query: 293  HLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI-EPPVPPM 351
            ++ N+ V+         S P  E  S       P       EP       P+ EPPVP  
Sbjct: 4897 NVSNLDVRQL-------SAPPPEEPSPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSP 4949

Query: 352  EHELSISEQQQPVQPSESPREVESS 376
                S  E  +P   +  P E E S
Sbjct: 4950 LPLASSPESARPKPRARPPEEGEDS 4974



 Score = 31.2 bits (69), Expect = 8.6
 Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 16/117 (13%)

Query: 159  SLAEIIGIIRQLST---PQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGP 215
            S  +I+ +++Q S    P +Q     N  S+ D     + PPE      EP  P   + P
Sbjct: 4871 SQLDILSLLKQESPAPEPPTQHSYTYN-VSNLDVRQLSAPPPE------EPSPPPSPLAP 4923

Query: 216  SQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMES 272
            S     P +   E L ++ +  L  E P   P  L   P S + +  A PPE   +S
Sbjct: 4924 S-----PASPPTEPLVELPTEPLA-EPPVPSPLPLASSPESARPKPRARPPEEGEDS 4974


>gi|224458301 family with sequence similarity 186, member A [Homo
            sapiens]
          Length = 2351

 Score = 92.0 bits (227), Expect = 4e-18
 Identities = 175/801 (21%), Positives = 295/801 (36%), Gaps = 134/801 (16%)

Query: 86   HLGPSASSEM---PAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER 142
            HLGP    E       P+   E+L   + T D       +P++         +K+  Q  
Sbjct: 955  HLGPHRRREKGKEKQKPERGLEDLERQIKTKDQMQMKETQPKEL--------EKMVIQTP 1006

Query: 143  LPVSP--KKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQ-NEYSSTDTPYPGSLP--- 196
            + +SP  K + KD  + +   E    ++ L     +K+ +      S     PG+LP   
Sbjct: 1007 MTLSPRWKSVLKDVQRSYEGKEFQRNLKTLENLPDEKEPISITPPPSLQYSLPGALPISG 1066

Query: 197  PELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS 256
              L       P  +++VG +    + + Q   TL   Q+  L      Q  Q LE   + 
Sbjct: 1067 QPLTKCIHLTPQQAQEVGITLTPQQAQAQGI-TLTLQQAQELGIPLTPQQAQALEILFTP 1125

Query: 257  MQQEA---PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
             Q +A   P  P ++ ++ +TL         P +DQA    P I++              
Sbjct: 1126 QQAQALGIPLTPQQTQVQGITLT--------PQQDQA----PGISL-------------- 1159

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPR- 371
                ++Q  Q+  I       P   QQ   +  P+ P +  EL I     P+ P ++   
Sbjct: 1160 ----TTQQAQKLGI-------PLTPQQAQALGIPLTPQQAQELGI-----PLTPQQAQAL 1203

Query: 372  EVESSPTQQETPGQP--PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
             V  +P Q +  G P  P+  +         Q   L  P    +   + +T+  +   E+
Sbjct: 1204 RVSLTPQQAQELGIPLTPQQAQALGITLTLQQAQQLGIPLTPQQAQALGITLTPKQVQEL 1263

Query: 430  GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAG-PLAVQQETSFQSPEPINN 488
            G  L  Q+A       G  + P   Q  G PL P+ ++  G PL  +Q  +   P     
Sbjct: 1264 GIPLTPQQA----QALGITLTPKQAQELGIPLNPQQAQTLGIPLTPKQAQALGIPF---- 1315

Query: 489  ENPSPTQQEAAAEHPQTAEEGESSLTHQEA-----PAQTPEFPNVVVAQPPEHSH---LT 540
              P   Q       PQ A+  E +LT Q+A     P  T +   + +   P+H+    + 
Sbjct: 1316 -TPQQAQALGIPLTPQQAQTQEITLTPQQAQALGMPLTTQQAQELGIPLTPQHAQALGMP 1374

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKE--------TPTQPPKKVVPQLRVYQGVTNPT 592
              T Q  +LG  +TP+    + +  T ++        TP Q  +  +P           T
Sbjct: 1375 LTTQQAQELGIPLTPQQAQALGMPLTTQQAQELGIPLTPQQAQELGIPFTPQQAQAQEIT 1434

Query: 593  PGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRT------IVSPKHPEVTLP 646
                QAQ    P    Q  +LG+T+TP+   E+G    P++       ++ P+  E+ +P
Sbjct: 1435 LTPQQAQALGMPLTAQQAQELGITLTPQQAQELGIPLTPQQAQALGIPLIPPQAQELGIP 1494

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
               Q Q Q   +     Q  +LG  +TP      + + AL     PP   E+ +P     
Sbjct: 1495 LTPQ-QAQALGILLIPPQAQELGIPLTP------QQAQALGIPLIPPQAQELGIP----- 1542

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE------TSTQPPDLGLAIIPEPT 760
                  LT   VQ L + L        E+  +P   +      T  Q  +LG+ + P+  
Sbjct: 1543 ------LTPQQVQALGIPLIPPQAQELEIPLTPQQAQALGIPLTPQQAQELGIPLTPQQA 1596

Query: 761  TETGHSTALEKTTAP----RPDRVQTLHRSLTE-------VTGPPTELEPAQDSLVQSES 809
             E G     ++  A      P + Q L  SLT        +T  P + +     +    +
Sbjct: 1597 QELGIPLTPQQAQAQGIPLTPQQAQALGISLTPQQAQAQGITLTPQQAQALGVPITPVNA 1656

Query: 810  YTQNKALTAPEEHKASTSTNI 830
            +     LT+ + H   +  N+
Sbjct: 1657 WVSAVTLTSEQTHALESPMNL 1677


>gi|239749951 PREDICTED: similar to mucin 2 [Homo sapiens]
          Length = 2639

 Score = 87.8 bits (216), Expect = 8e-17
 Identities = 146/598 (24%), Positives = 197/598 (32%), Gaps = 88/598 (14%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P  +  T T  PT    S+Q+   TPI     V P+ T       P   P+    +++  
Sbjct: 1313 PTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQ-TPTTTPITTTTTVTPT 1371

Query: 361  QQPV---QPSESPREVES------SPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVS 411
              P     P+ +P    +      +PT  +TP   P     TV+P     T         
Sbjct: 1372 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTP-----TPTPTGTQTP 1426

Query: 412  VKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP 471
               P    T         GT      A T  S       P   Q   P   P ++     
Sbjct: 1427 TTTPITTTTTVTPTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQ--TPTTTPITT----- 1479

Query: 472  LAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVA 531
                  T   +P P   + P+PT     A    T      + T  + P  TP      V 
Sbjct: 1480 ----TTTVTPTPTPTGTQTPTPT-----AITTTTTVTPTPTPTGTQTPTSTPITTTTTVT 1530

Query: 532  QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P  +     T  P+    T+TP        +PT  +TPT  P               P
Sbjct: 1531 PTPTPTGTQTPTPTPISTTTTVTPTP------TPTGTQTPTTTPITTTT-------TVTP 1577

Query: 592  TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL---PHP 648
            TP     Q P     T  L+    T+TP PT      T  K T V+P     T+   P P
Sbjct: 1578 TPTPTGTQTP-----TTVLITTTTTMTPTPT-----PTSTKSTTVTPITTTTTVTATPTP 1627

Query: 649  DQVQTQH----SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSD 704
               QT      S  T  T  P     +  P + T   P   L T+ PP   PE + P + 
Sbjct: 1628 TGTQTPTMIPISTTTTVTPTPTPTTGSTGPPTHTSTAPIAELTTSNPP---PESSTPQTS 1684

Query: 705  KGQAQHSHLTQAT----VQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPT 760
            +  +  S LT++T      P  +E+T T  P+T   P+ T+   +  PP       P  T
Sbjct: 1685 RSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPP-STTTSPPGT 1741

Query: 761  TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---------TELEPAQDSLVQSESYT 811
               G +T    ++AP P  VQT   S    T  P         T L P   S++      
Sbjct: 1742 PTRGTTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVL--ICCV 1797

Query: 812  QNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
             N    AP EE    T  + C    C    LSC            P P P     T T
Sbjct: 1798 LNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCPSTPSPTPTPSKSTPT 1852



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 97/389 (24%), Positives = 127/389 (32%), Gaps = 61/389 (15%)

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQ 573
            T  E P  TP      V   P  +     T  P+    T+TP        +PT  +TPT 
Sbjct: 1306 TTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTP------TPTGTQTPTT 1359

Query: 574  PPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKR 633
             P               PTP     Q P +  +T        T+TP P T  G  TP   
Sbjct: 1360 TPITTTT-------TVTPTPTPTGTQTPTTTPITTT-----TTVTPTP-TPTGTQTPTST 1406

Query: 634  TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP---KSMTEVEPSTALMTTA 690
             I +      T P P   QT        T  P+    T+TP    + T+    TA+ TT+
Sbjct: 1407 PITTTTTVTPT-PTPTGTQT-------PTTTPITTTTTVTPTPTPTGTQAPTPTAITTTS 1458

Query: 691  -------PPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEE 743
                   P       T P +       +     T  P    +T TT  T    P+ T   
Sbjct: 1459 TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTPTAITTTTTVTPTPTPTGTQTP 1518

Query: 744  TSTQPPDLGLAIIPEPT-------TETGHSTALEKTTAPRPDRVQTLH----RSLTEVTG 792
            TST P      + P PT       T T  ST    T  P P   QT       + T VT 
Sbjct: 1519 TST-PITTTTTVTPTPTPTGTQTPTPTPISTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1577

Query: 793  PPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCT-------CGDEMLSCID 845
             PT       + V   + T       P   K++T T I    T        G +  + I 
Sbjct: 1578 TPTPTGTQTPTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTATPTPTGTQTPTMIP 1637

Query: 846  LNPEQRLRQVPVPE-----PNTHNGTFTI 869
            ++    +   P P      P TH  T  I
Sbjct: 1638 ISTTTTVTPTPTPTTGSTGPPTHTSTAPI 1666



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 95/488 (19%), Positives = 148/488 (30%), Gaps = 98/488 (20%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            +TP +   T+    + T T  P S P          P P+    P+     P T      
Sbjct: 1382 TTPITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTT---TPITTTTTVT 1438

Query: 231  EDIQSSSLQQEAPAQLP--QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
                 +  Q   P  +     +   P+    + P   P ++  ++T        Q P   
Sbjct: 1439 PTPTPTGTQAPTPTAITTTSTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP--- 1495

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
                        P  +  T T  PT     +Q    TPI     V P+ T        P 
Sbjct: 1496 -----------TPTAITTTTTVTPTPTPTGTQTPTSTPITTTTTVTPTPTPTGTQTPTPT 1544

Query: 349  PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP---PGHHQTHHL 405
            P     +S +    P            +PT  +TP   P     TV+P   P   QT   
Sbjct: 1545 P-----ISTTTTVTPT----------PTPTGTQTPTTTPITTTTTVTPTPTPTGTQT--- 1586

Query: 406  ASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPES 465
              P+  +      +T    P++   T++     TT ++ +     P       P ++P S
Sbjct: 1587 --PTTVLITTTTTMTPTPTPTSTKSTTVTPITTTTTVTAT-----PTPTGTQTPTMIPIS 1639

Query: 466  SEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEF 525
            +           T   +P P       PT       H  TA   E + ++    + TP+ 
Sbjct: 1640 T---------TTTVTPTPTPTTGSTGPPT-------HTSTAPIAELTTSNPPPESSTPQ- 1682

Query: 526  PNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVY 585
                          +++T  PL    T+         L P ++ T T PP          
Sbjct: 1683 -------------TSRSTSSPLTESTTLLS------TLPPAIEMTSTAPPS--------- 1714

Query: 586  QGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL 645
               T   P      H +SP  +      G   TP   T  G S+ P  + V         
Sbjct: 1715 ---TPTAPTTTSGGHTLSPPPSTTTSPPG---TPTRGTTTGSSSAPTPSTVQTTTTSAWT 1768

Query: 646  PHPDQVQT 653
            P P  + T
Sbjct: 1769 PTPTPLST 1776



 Score = 35.0 bits (79), Expect = 0.60
 Identities = 47/199 (23%), Positives = 65/199 (32%), Gaps = 24/199 (12%)

Query: 681  EPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
            +P+T   TT   P    +T   +       +     T  P+    T+T  PT     +PT
Sbjct: 1299 QPTTMTTTTTENPTPTPITTTTTVTPTPTPTSTQSTTPTPITTTTTVTPTPTPTGTQTPT 1358

Query: 741  TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTE 789
            T   +T        + P PT   T+T  +T +  TT     P P   QT       + T 
Sbjct: 1359 TTPITTT-----TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTSTPITTTTT 1413

Query: 790  VTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPE 849
            VT  PT       +     + T       P   +A T T I    T        +   P 
Sbjct: 1414 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQAPTPTAITTTST--------VTPTPT 1465

Query: 850  QRLRQVPVPEPNTHNGTFT 868
                Q P   P T   T T
Sbjct: 1466 PTGTQTPTTTPITTTTTVT 1484


>gi|91982772 mucin 17 [Homo sapiens]
          Length = 4493

 Score = 87.0 bits (214), Expect = 1e-16
 Identities = 162/763 (21%), Positives = 279/763 (36%), Gaps = 90/763 (11%)

Query: 95  MPAPPQESTENLVPFLDTWDSAGELP-LEPEQFLASQQDLKDKLSPQERLPVSPKKLKKD 153
           M  P +ES  + + F+ T      LP  E    L  + D+   L+   +   SP   +  
Sbjct: 149 MSTPSEESISSTMAFVST----APLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPEST 204

Query: 154 PAQRWSLAEIIGIIRQLSTPQSQKQTLQNE-YSSTDTPYPGSLPPELRVKSDEPPGPSEQ 212
              + + +E  G     S P S  +   +E  +   TP   S P  +  ++   P  +E 
Sbjct: 205 TIPKSTNSE--GSTPLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSPTTAE- 261

Query: 213 VGPSQFHLEPE------TQNPETLEDIQSSSLQQ----EAPAQLPQLLEEEPSSMQQ--E 260
            GPS  +  P       T+ P ++  + SS         A   +P +   E SS     E
Sbjct: 262 -GPSLSNSAPSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAE 320

Query: 261 APALPPESSMESLT-LPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITS--------- 310
             ++P  +  E  T L +   S  P    +    +  +++ P D    +T+         
Sbjct: 321 GTSIPTSTYTEGSTPLTSTPASTMPVATSE----MSTLSITPVDTSTLVTTSTEPSSLPT 376

Query: 311 --EPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSE 368
             E T+   S+ ++  TP+             EA     +P ++ +  ++   +    S 
Sbjct: 377 TAEATSMLTSTLSEGSTPLTNMPVSTILVASSEASTTSTIP-VDSKTFVTTASEA---SS 432

Query: 369 SPREVESSPTQQETPGQ---PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEP 425
           SP   E +     TP +   P     V+ +P    +  +L++  V  K    Q+T + E 
Sbjct: 433 SPTTAEDTSIATSTPSEGSTPLTSMPVSTTPVASSEASNLSTTPVDSK---TQVTTSTEA 489

Query: 426 SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEP 485
           S+   T+ V+   T+  S     +   ++       +P +S EA  L         S  P
Sbjct: 490 SSSPPTAEVNSMPTSTPSEGSTPLTSMSVS-----TMPVASSEASTL---------STTP 535

Query: 486 INNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQ 545
           ++   P  T  EA++    T  EG S  T   +   TP     V  +    S  +  +  
Sbjct: 536 VDTSTPVTTSSEASSS--STTPEGTSIPTSTPSEGSTPLTNMPVSTRLVVSSEASTTSTT 593

Query: 546 PLDLGFTITPESKTEVELSPTMKETPTQPPKK------VVPQLRVYQGVTNPTPGQDQAQ 599
           P D    +T  S  E   S T  E  + P          +  + V   +   +     + 
Sbjct: 594 PADSNTFVTTSS--EASSSSTTAEGTSMPTSTYSERGTTITSMSVSTTLVASSEASTLST 651

Query: 600 HPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLT 659
            PV  +  V         T   TT  G S P   T      P  ++P    +       T
Sbjct: 652 TPVDSNTPVTT---STEATSSSTTAEGTSMPTS-TYTEGSTPLTSMPVNTTLVASSEAST 707

Query: 660 RATVQPLDLGFTITPKSMTEVEPSTA----LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
            +T  P+D    +T  +     P+TA    + T+ P  G   +T  P  K     S  + 
Sbjct: 708 LSTT-PVDTSTPVTTSTEASSSPTTADGASMPTSTPSEGSTPLTSMPVSKTLLTSSEAST 766

Query: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQP---PDLGLAIIPE-PTTETGHSTALEK 771
            +  PLD    ITT  +TE   SPTT E ++ P   P  G  ++   P + T  ++    
Sbjct: 767 LSTTPLDTSTHITT--STEASCSPTTTEGTSMPISTPSEGSPLLTSIPVSITPVTSPEAS 824

Query: 772 TTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNK 814
           T +  P    +   + TEV+  PT   PA+ + + + +Y++ +
Sbjct: 825 TLSTTPVDSNSPVTTSTEVSSSPT---PAEGTSMPTSTYSEGR 864



 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 159/776 (20%), Positives = 266/776 (34%), Gaps = 66/776 (8%)

Query: 71   SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQ 130
            S  +P L + P     +    +S +   P +S   ++   +   S    P+  E      
Sbjct: 2098 SEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTEVSSS----PIPTEGTSMQT 2153

Query: 131  QDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSS--TD 188
                D+ +P   +PVS   +        S   +       ++ +++     +E +S  T 
Sbjct: 2154 STYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEARSSPTTSEGTSMPTS 2213

Query: 189  TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEP-ETQNPETLEDIQSSSLQQEAPAQLP 247
            TP  GS P      S  P   SE    S     P +T  P T     +SS        +P
Sbjct: 2214 TPSEGSTPFTSMPVSTMPVVTSEA---STLSATPVDTSTPVTTSTEATSSPTTAEGTSIP 2270

Query: 248  QLLEEEPSSMQQEAPA---LPPESSMESL-TLP---------NHEVSVQPPGEDQAYYHL 294
                 E ++     P    L   S + +L T P         + E S  PP  +     +
Sbjct: 2271 TSTLSEGTTPLTSIPVSHTLVANSEVSTLSTTPVDSNTPFTTSTEASSPPPTAEGT--SM 2328

Query: 295  PNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEP 346
            P  T    +  +T        + S  T+   ++ A   TP+    +   S T  +    P
Sbjct: 2329 PTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADTSTPVTTYSQAGSSPTTADDTSMP 2388

Query: 347  PVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLA 406
                 E    ++       P  S      S T  +T        E + SP     T    
Sbjct: 2389 TSTYSEGSTPLTSVPVSTMPVVSSEASTHSTTPVDTSTPVTTSTEASSSPTTAEGTSIPT 2448

Query: 407  SPSVSVKPPDVQLTIAAEP--SAEVGT-----------SLVHQEATTRLSGSGNDVEPPA 453
            SP      P   + ++  P  S+E GT                EA++  + + + V P +
Sbjct: 2449 SPPSEGTTPLASMPVSTTPVVSSEAGTLSTTPVDTSTPMTTSTEASSSPTTAEDIVVPIS 2508

Query: 454  IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSL 513
                G  LL        P+A   E S  S  P+++ +P  T  E ++    T+ EG S  
Sbjct: 2509 TASEGSTLLTSIPVSTTPVA-SPEASTLSTTPVDSNSPVVTSTEISSS--ATSAEGTSMP 2565

Query: 514  THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSP-TMKET-- 570
            T   +   TP     V  +P   S  +  +  P+D    +T  + TE   SP T K+T  
Sbjct: 2566 TSTYSEGSTPLRSMPVSTKPLASSEASTLSTTPVDTSIPVT--TSTETSSSPTTAKDTSM 2623

Query: 571  PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTP 630
            P   P +V   L      T P    + +    +P  T  L+      +  PTT  G S P
Sbjct: 2624 PISTPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMP 2683

Query: 631  PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA----L 686
               +    +   +T          +S  +  +  P+D    +T  +     P+TA    +
Sbjct: 2684 --TSTPGERSTPLTNILVSTTLLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTSM 2741

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETST 746
              + P  G   +T           S  +  +   +D  + +TT  +TE   SPTT E ++
Sbjct: 2742 RISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTT--STEASSSPTTAEVTS 2799

Query: 747  Q----PPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
                 P +    +   P   T  +++   T +  P    T   + T+ +  PT  E
Sbjct: 2800 MPTSTPSETSTPLTSMPVNHTPVASSEAGTLSTTPVDTSTPVTTSTKASSSPTTAE 2855



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 149/686 (21%), Positives = 230/686 (33%), Gaps = 70/686 (10%)

Query: 170  LSTPQSQKQTL--QNEYSSTDTPYPGSLPP-----ELRVKSDEPPGPSEQVGPSQFHLEP 222
            L+TP   K  +   NE SS+ TP  G+  P     E R      P  +  V  S   +  
Sbjct: 1299 LTTPVDTKGPVVTSNEVSSSPTPAEGTSMPTSTYSEGRTPLTSIPVNTTLVASSAISILS 1358

Query: 223  ET----QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAP-ALPPESSMESLTLPN 277
             T      P T      SS        +P     E ++     P +  P  S E+ TL  
Sbjct: 1359 TTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPLTSIPVSTTPVVSSEASTLSA 1418

Query: 278  HEVSVQPPGEDQAYYHLPNITVK--------PADVEVTITSEPTNETESSQAQQETPIQF 329
              V    PG   A       T +        P++ +  + S P + T  + ++  T    
Sbjct: 1419 TPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLKSIPVSNTPVANSEASTLSTT 1478

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQ--------PVQPSE-SPREVESSPTQQ 380
            P +         A    P P     ++IS   +        PV  +  +  E+ S  T  
Sbjct: 1479 PVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTSIPVSTTTVASSEINSLSTTP 1538

Query: 381  ETPGQPPEHHEVTVSPPG-------HHQTHHLASPSVSVKPPDVQLTIAAEP-------- 425
                 P   +    S P           T+   S  ++  P    L +++E         
Sbjct: 1539 AVTSTPVTTYSQASSSPTTADGTSMQTSTYSEGSTPLTSLPVSTMLVVSSEANTLSTTPI 1598

Query: 426  -SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
             S    T+     ++T   GS   +  P+    G PLL        P+A   E S  S  
Sbjct: 1599 DSKTQVTASTEASSSTTAEGSSMTISTPS---EGSPLLTSIPVSTTPVA-SPEASTLSTT 1654

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            P+++ +P  T  E ++    T  EG S  T      +TP     V   P   S ++  + 
Sbjct: 1655 PVDSNSPVITSTEVSSS--PTPAEGTSMPTSTYTEGRTPLTSITVRTTPVASSAISTLST 1712

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             P+D    +T  + TE   SPT  E  + P   P +    L      T P    + +   
Sbjct: 1713 TPVDNSTPVT--TSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTTPVLSSEASTLS 1770

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRA 661
             +P  T   +      T  PTT  G S P   T+     P  + P        +S  +  
Sbjct: 1771 ATPIDTSTPVTTSTEATSSPTTAEGTSIPTS-TLSEGMTPLTSTP-VSHTLVANSEASTL 1828

Query: 662  TVQPLDLGFTITPKSMTEVEPSTALMTT-APPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P+D        S + V  STA+ ++  P  G    T  PS+   A  S     T   
Sbjct: 1829 STTPVD--------SNSPVVTSTAVSSSPTPAEGTSIATSTPSEGSTALTSIPVSTTTVA 1880

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGH---STALEKTTAPRP 777
                 T++T P     P  T  + S+ P     + +P  T   G    ++    TT    
Sbjct: 1881 SSETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSMPTSTPREGRPPLTSIPVSTTTVAS 1940

Query: 778  DRVQTLHRSLTEVTGPPTELEPAQDS 803
              + TL  +L +   P T    A  S
Sbjct: 1941 SEINTLSTTLADTRTPVTTYSQASSS 1966



 Score = 76.6 bits (187), Expect = 2e-13
 Identities = 171/855 (20%), Positives = 281/855 (32%), Gaps = 90/855 (10%)

Query: 43   VKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
            V   + +T++      P ++  +  P  +P   + P      +H  P ASSE        
Sbjct: 2776 VDTSIPVTTSTEASSSPTTAEVTSMPTSTPSETSTPLTSMPVNHT-PVASSEAGTLSTTP 2834

Query: 103  TENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAE 162
             +   P + T   A   P   E  +       +  +    +PVS   +    A   S   
Sbjct: 2835 VDTSTP-VTTSTKASSSPTTAEGIVVPISTASEGSTLLTSIPVSTTPVASSEASTLSTTP 2893

Query: 163  IIGIIRQLSTPQ--SQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHL 220
            +   I   ++ +  S   T +       TP   S P    + S  P   SE    S    
Sbjct: 2894 VDTSIPVTTSTEGSSSPTTAEGTSMPISTPSEVSTPLTSILVSTVPVAGSEA---STLST 2950

Query: 221  EP-ETQNPETLEDIQSSSLQQEAPAQLP-QLLEEEPSSMQQEAPALPPESSMESLTLPNH 278
             P +T+ P T     SSS        +P     E  + +   + +  P +S E+ TL   
Sbjct: 2951 TPVDTRTPVTTSAEASSSPTTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRT 3010

Query: 279  EVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSAT 338
                  P            T +   + ++  SE +    S      TP+  PE    S T
Sbjct: 3011 PADTSTPVTTSTEASSSPTTAEGTGIPISTPSEGSTPLTSIPVST-TPVAIPEASTLSTT 3069

Query: 339  --QQEAPI-------EPPVPPMEHELSISEQQQPVQP------------SESPREVESSP 377
                 +P+         P P     + IS   +   P            S +   + ++P
Sbjct: 3070 PVDSNSPVVTSTEVSSSPTPAEGTSMPISTYSEGSTPLTGVPVSTTPVTSSAISTLSTTP 3129

Query: 378  TQQETP-GQPPEHHEVTVSPPGHHQ---THHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
                TP     E H    +  G      T    S  ++  P    L +++E S    T +
Sbjct: 3130 VDTSTPVTTSTEAHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPV 3189

Query: 434  -------VHQEATTRLSGSGNDVEPPAIQHGGPPL--LPESSEEAGPLAVQQETSFQSPE 484
                      EAT+  +  G  +       G  PL  +P S+    P+A   E S  S  
Sbjct: 3190 DTSTPVTTSTEATSSTTAEGTSIPTSTPSEGMTPLTSVPVSNT---PVA-SSEASILSTT 3245

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            P+++  P  T  EA++  P    EG S  T   +   TP     V       S  +  + 
Sbjct: 3246 PVDSNTPLTTSTEASSSPPTA--EGTSMPTSTPSEGSTPLTSMPVSTTTVASSETSTLST 3303

Query: 545  QPLDLGFTITPESKTEVELSPTMKE---TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
             P D    +T  S  +   SP + +    PT    +    L      T P    + +   
Sbjct: 3304 TPADTSTPVTTYS--QASSSPPIADGTSMPTSTYSEGSTPLTNMSFSTTPVVSSEASTLS 3361

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH---PEVTLPHPDQVQTQHSHL 658
             +P  T   +      +  PTT  G S P      SP     P  ++P         S +
Sbjct: 3362 TTPVDTSTPVTTSTEASLSPTTAEGTSIPTS----SPSEGTTPLASMP-VSTTPVVSSEV 3416

Query: 659  TRATVQPLDLGFTITPKSMTEVEPS----TALMTTAPPPGHPEVTLPPSDKGQAQHSHLT 714
               +  P+D    +T  +     P+    T+L T+    G   +++ P        S  +
Sbjct: 3417 NTLSTTPVDSNTLVTTSTEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEAS 3476

Query: 715  QATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG------LAIIPEPTTETGHSTA 768
              +  P+D    +TT   T    SPTT E ++ P          L  +P  TT    S A
Sbjct: 3477 TLSTTPVDTSTPVTTSSPT--NSSPTTAEVTSMPTSTAGEGSTPLTNMPVSTTPVASSEA 3534

Query: 769  LEKTTAPRPDRVQTLHRSLTEVTGPPTELE--------PAQDS-----LVQSESYTQNKA 815
               +T P      T   S ++ +  P  L+        P++ S     ++ S +Y  +  
Sbjct: 3535 STLSTTPVDS--NTFVTSSSQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTYVTSSE 3592

Query: 816  LTAPEEHKASTSTNI 830
             + P       ST +
Sbjct: 3593 ASTPSTPSVDRSTPV 3607



 Score = 72.4 bits (176), Expect = 3e-12
 Identities = 163/728 (22%), Positives = 244/728 (33%), Gaps = 110/728 (15%)

Query: 171  STPQSQKQTLQNEYSS-TDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
            S P S K    +E S+ + TP   S+P     ++   P  ++           +T  P +
Sbjct: 2578 SMPVSTKPLASSEASTLSTTPVDTSIPVTTSTETSSSPTTAK-----------DTSMPIS 2626

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEP--SSMQQEAPALPPESSMESLTLPNHEVSVQP--- 284
                 S+SL     + +P    E    S+   +   L   S+  S +    E S  P   
Sbjct: 2627 TPSEVSTSLTSILVSTMPVASSEASTLSTTPVDTRTLVTTSTGTSSSPTTAEGSSMPTST 2686

Query: 285  PGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP- 343
            PGE      L NI V        + +   +   ++     TP+    E   S T  E   
Sbjct: 2687 PGERST--PLTNILVSTT----LLANSEASTLSTTPVDTSTPVTTSAEASSSPTTAEGTS 2740

Query: 344  --IEPPVPPMEHELSISEQQQPVQPSESPR----------------EVESSPTQQETPGQ 385
              I  P        SI     PV  SE+                  E  SSPT  E    
Sbjct: 2741 MRISTPSDGSTPLTSILVSTLPVASSEASTVSTTAVDTSIPVTTSTEASSSPTTAEVTSM 2800

Query: 386  PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGS 445
            P      T +P      +H  +P  S +   +  T   + S  V TS     + T   G 
Sbjct: 2801 PTSTPSETSTPLTSMPVNH--TPVASSEAGTLSTT-PVDTSTPVTTSTKASSSPTTAEGI 2857

Query: 446  GNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQT 505
               V P +    G  LL        P+A   E S  S  P++   P  T  E ++  P T
Sbjct: 2858 ---VVPISTASEGSTLLTSIPVSTTPVA-SSEASTLSTTPVDTSIPVTTSTEGSSS-PTT 2912

Query: 506  AEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSP 565
            AE G S      +   TP    +V   P   S  +  +  P+D    +T  +  E   SP
Sbjct: 2913 AE-GTSMPISTPSEVSTPLTSILVSTVPVAGSEASTLSTTPVDTRTPVT--TSAEASSSP 2969

Query: 566  TMKETPTQP---PKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPT 622
            T  E  + P   P +    L      T P    + +    +P+ T   +      +  PT
Sbjct: 2970 TTAEGTSMPISTPGERRTPLTSMSVSTMPVASSEASTLSRTPADTSTPVTTSTEASSSPT 3029

Query: 623  TEVGH----STPPKR----TIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITP 674
            T  G     STP +     T +      V +P    + T         V   ++  + TP
Sbjct: 3030 TAEGTGIPISTPSEGSTPLTSIPVSTTPVAIPEASTLSTTPVDSNSPVVTSTEVSSSPTP 3089

Query: 675  KSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTE 734
               T +  ST    + P  G P  T P +       S ++  +  P+D    +TT  +TE
Sbjct: 3090 AEGTSMPISTYSEGSTPLTGVPVSTTPVTS------SAISTLSTTPVDTSTPVTT--STE 3141

Query: 735  VKPSPTTEETSTQP------------------------PDLGLAIIPEPT-------TET 763
               SPTT E ++ P                         D  L+  P  T       TE 
Sbjct: 3142 AHSSPTTSEGTSMPTSTPSEGSTPLTYMPVSTMLVVSSEDSTLSATPVDTSTPVTTSTEA 3201

Query: 764  GHSTALEKTTAPRPDRVQTLHRSLTEVTGPP---TELEPAQDSLVQSESYTQNKALTAPE 820
              ST  E T+ P      T    +T +T  P   T +  ++ S++ +     N  LT   
Sbjct: 3202 TSSTTAEGTSIP----TSTPSEGMTPLTSVPVSNTPVASSEASILSTTPVDSNTPLTTST 3257

Query: 821  EHKASTST 828
            E  +S  T
Sbjct: 3258 EASSSPPT 3265



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 130/590 (22%), Positives = 202/590 (34%), Gaps = 81/590 (13%)

Query: 267  ESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETP 326
            E+S    T     + +  P E       P +T  P  +   +TS   +   ++     +P
Sbjct: 783  EASCSPTTTEGTSMPISTPSEGS-----PLLTSIPVSI-TPVTSPEASTLSTTPVDSNSP 836

Query: 327  IQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ----------------QPVQ---PS 367
            +    EV  S T  E    P     E    ++                    PV    P 
Sbjct: 837  VTTSTEVSSSPTPAEGTSMPTSTYSEGRTPLTSMPVSTTLVATSAISTLSTTPVDTSTPV 896

Query: 368  ESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQL-TIAAEP- 425
             +  E  SSPT  E    P        S PG   T   + P  +      +  T++A P 
Sbjct: 897  TNSTEARSSPTTSEGTSMP-------TSTPGEGSTPLTSMPDSTTPVVSSEARTLSATPV 949

Query: 426  --SAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
              S  V TS     + T   G+      P+   G  PL   S+  +  L    E S  S 
Sbjct: 950  DTSTPVTTSTEATSSPTTAEGTSIPTSTPS--EGTTPLT--STPVSHTLVANSEASTLST 1005

Query: 484  EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQAT 543
             P+++  P  T  EA++  P    EG S  T   +   TP                   T
Sbjct: 1006 TPVDSNTPLTTSTEASS--PPPTAEGTSMPTSTPSEGSTP------------------LT 1045

Query: 544  VQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-- 601
              P+      + E+ T +  +P    TP     +         G + PT    +   P  
Sbjct: 1046 RMPVSTTMVASSETST-LSTTPADTSTPVTTYSQASSSSTTADGTSMPTSTYSEGSTPLT 1104

Query: 602  ---VSPSVTVQLLDLGLTITPEPTT-EVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSH 657
               VS  + V      L+ TP  T+  V  ST    +  + +   +    P +  T  + 
Sbjct: 1105 SVPVSTRLVVSSEASTLSTTPVDTSIPVTTSTEASSSPTTAEGTSIPTSPPSEGTTPLAS 1164

Query: 658  LTRATVQPLDLGFTITPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHL 713
            +  +T   L +       S T V+  T + T+    +PPP     ++P S  G+ + + L
Sbjct: 1165 MPVSTT--LVVSSEANTLSTTPVDSKTQVATSTEASSPPPTAEVTSMPTSTPGE-RSTPL 1221

Query: 714  TQATVQPLDLEL----TITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTAL 769
            T   V+   +      T++T P     P  T+ ETS+ P       +P  TT  G ST L
Sbjct: 1222 TSMPVRHTPVASSEASTLSTSPVDTSTPVTTSAETSSSPTTAEGTSLPTSTTSEG-STLL 1280

Query: 770  EKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAP 819
              T+ P    + T   + T +T P     P   S   S S T  +  + P
Sbjct: 1281 --TSIPVSTTLVTSPEASTLLTTPVDTKGPVVTSNEVSSSPTPAEGTSMP 1328



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 155/733 (21%), Positives = 240/733 (32%), Gaps = 73/733 (9%)

Query: 89   PSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
            P ASS +        +N  P + T   A   P   E          +  +P   +PVS  
Sbjct: 1701 PVASSAISTLSTTPVDNSTP-VTTSTEARSSPTTSEGTSMPNSTPSEGTTPLTSIPVSTT 1759

Query: 149  KLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPG 208
             +    A   S   I       STP     T   E +S+ T   G+  P   +     P 
Sbjct: 1760 PVLSSEASTLSATPI-----DTSTPV----TTSTEATSSPTTAEGTSIPTSTLSEGMTPL 1810

Query: 209  PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             S  V  +       +    T  D  S  +   A +  P      P+     A + P E 
Sbjct: 1811 TSTPVSHTLVANSEASTLSTTPVDSNSPVVTSTAVSSSPT-----PAEGTSIATSTPSEG 1865

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQ 328
            S    ++P    +V    E       P +T  P      ++S PT    SS      P  
Sbjct: 1866 STALTSIPVSTTTVAS-SETNTLSTTPAVTSTPVTTYAQVSSSPTTADGSSM-----PTS 1919

Query: 329  FPEEVEPSATQQEAPIEPPVPPMEHELS--ISEQQQPVQPSESPREVESSPTQQETPGQP 386
             P E  P  T              + LS  +++ + PV       +  SSPT  +    P
Sbjct: 1920 TPREGRPPLTSIPVSTTTVASSEINTLSTTLADTRTPVTTYS---QASSSPTTADGTSMP 1976

Query: 387  -PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL-VHQEATTRLSG 444
             P + E               S  ++  P    L +++E S    T +     ATT   G
Sbjct: 1977 TPAYSE--------------GSTPLTSMPLSTTLVVSSEASTLSTTPVDTSTPATTSTEG 2022

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLA---------VQQETSFQSPEPINNENPSPTQ 495
            S +    P    G        SE   PLA         V  E +  S  P++++      
Sbjct: 2023 SSS----PTTAGGTSIQTSTPSERTTPLAGMPVSTTLVVSSEGNTLSTTPVDSKTQVTNS 2078

Query: 496  QEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITP 555
             EA++           S   + +P  T    +      PE S L+   V       T T 
Sbjct: 2079 TEASSSATAEGSSMTISAPSEGSPLLTSIPLSTTPVASPEASTLSTTPVDSNSPVITSTE 2138

Query: 556  ESKTEVELSPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTV-QLLDL 613
             S + +    T  +T T   ++  +  + V   V   +     +  PV  S  V    + 
Sbjct: 2139 VSSSPIPTEGTSMQTSTYSDRRTPLTSMPVSTTVVASSAISTLSTTPVDTSTPVTNSTEA 2198

Query: 614  GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT 673
              + T    T +  STP + +      P  T+P    V T  +    AT  P+D    +T
Sbjct: 2199 RSSPTTSEGTSMPTSTPSEGSTPFTSMPVSTMP----VVTSEASTLSAT--PVDTSTPVT 2252

Query: 674  PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
              +     P+TA  T+ P     E T P +      H+ +  + V       T++T P  
Sbjct: 2253 TSTEATSSPTTAEGTSIPTSTLSEGTTPLTSI-PVSHTLVANSEVS------TLSTTPVD 2305

Query: 734  EVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALE---KTTAPRPDRVQTLHRSLTEV 790
               P  T+ E S+ PP      +P  T+  G++        TT        TL  +  + 
Sbjct: 2306 SNTPFTTSTEASSPPPTAEGTSMPTSTSSEGNTPLTRMPVSTTMVASFETSTLSTTPADT 2365

Query: 791  TGPPTELEPAQDS 803
            + P T    A  S
Sbjct: 2366 STPVTTYSQAGSS 2378



 Score = 57.8 bits (138), Expect = 9e-08
 Identities = 175/835 (20%), Positives = 282/835 (33%), Gaps = 130/835 (15%)

Query: 50   TSNPLGPPEPWSSHSSHFPRE-----SPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            TS P+  P   S   +  P       SP A TL   P D  +   + S+E+ + P  +  
Sbjct: 794  TSMPISTPSEGSPLLTSIPVSITPVTSPEASTLSTTPVD-SNSPVTTSTEVSSSPTPAEG 852

Query: 105  NLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKK-LKKDPAQRWSLAEI 163
              +P   +  S G  PL     +++       +S     PV     +      R S    
Sbjct: 853  TSMP--TSTYSEGRTPLTSMP-VSTTLVATSAISTLSTTPVDTSTPVTNSTEARSSPTTS 909

Query: 164  IGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE 223
             G     STP      L +   ST TP   S   E R  S  P   S  V  S       
Sbjct: 910  EGTSMPTSTPGEGSTPLTSMPDST-TPVVSS---EARTLSATPVDTSTPVTTST----EA 961

Query: 224  TQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSS----MQQEAPALP--PESSMESLTLPN 277
            T +P T E    +S+    P++    L   P S       EA  L   P  S   LT   
Sbjct: 962  TSSPTTAE---GTSIPTSTPSEGTTPLTSTPVSHTLVANSEASTLSTTPVDSNTPLTTST 1018

Query: 278  HEVSVQPPGEDQAYYHLPNITVKPADVEVT--------ITSEPTNETESSQAQQETPIQF 329
               S  P  E  +   +P  T       +T        + S  T+   ++ A   TP+  
Sbjct: 1019 EASSPPPTAEGTS---MPTSTPSEGSTPLTRMPVSTTMVASSETSTLSTTPADTSTPVTT 1075

Query: 330  PEEVEPSATQQEAPIEPPVP-----------PMEHELSISEQQQPVQ--------PSESP 370
              +   S+T  +    P              P+   L +S +   +         P  + 
Sbjct: 1076 YSQASSSSTTADGTSMPTSTYSEGSTPLTSVPVSTRLVVSSEASTLSTTPVDTSIPVTTS 1135

Query: 371  REVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVG 430
             E  SSPT  E    P        SPP    T  LAS  VS       L +++E +  + 
Sbjct: 1136 TEASSSPTTAEGTSIP-------TSPPSEGTTP-LASMPVSTT-----LVVSSEANT-LS 1181

Query: 431  TSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLA---------VQQETSFQ 481
            T+ V  +     S   +   P A     P   P   E + PL             E S  
Sbjct: 1182 TTPVDSKTQVATSTEASSPPPTAEVTSMPTSTP--GERSTPLTSMPVRHTPVASSEASTL 1239

Query: 482  SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
            S  P++   P  T  E ++  P TAE G S  T     + T E   ++ + P   + +T 
Sbjct: 1240 STSPVDTSTPVTTSAETSSS-PTTAE-GTSLPT-----STTSEGSTLLTSIPVSTTLVTS 1292

Query: 542  ATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
                 L    T   ++K  V  S  +  +PT             +G + PT    + + P
Sbjct: 1293 PEASTL---LTTPVDTKGPVVTSNEVSSSPTPA-----------EGTSMPTSTYSEGRTP 1338

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPE----VTLP--HPDQVQTQ- 654
            ++       L     I+   TT V +STP   +  +   P      ++P  +P +  T  
Sbjct: 1339 LTSIPVNTTLVASSAISILSTTPVDNSTPVTTSTEACSSPTTSEGTSMPNSNPSEGTTPL 1398

Query: 655  -----------HSHLTRATVQPLDLGFTITPKSMTEVEPSTA----LMTTAPPPGHPEVT 699
                        S  +  +  P+D     T  +     P+TA    + T+ P  G   + 
Sbjct: 1399 TSIPVSTTPVVSSEASTLSATPVDTSTPGTTSAEATSSPTTAEGISIPTSTPSEGKTPLK 1458

Query: 700  LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT--TEETSTQPPDLGLAIIP 757
              P       +S  +  +  P+D    + T       P+P   T    + P +   A+  
Sbjct: 1459 SIPVSNTPVANSEASTLSTTPVDSNSPVVTSTAVSSSPTPAEGTSIAISTPSEGSTALTS 1518

Query: 758  EPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQ 812
             P + T  +++   + +  P    T   + ++ +  PT    A  + +Q+ +Y++
Sbjct: 1519 IPVSTTTVASSEINSLSTTPAVTSTPVTTYSQASSSPT---TADGTSMQTSTYSE 1570



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 155/742 (20%), Positives = 246/742 (33%), Gaps = 114/742 (15%)

Query: 171  STPQSQKQTLQNEYS-STDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
            ST  S   T+    S  T T   GS P  +   S  P   SE    S       T   +T
Sbjct: 3433 STEASSSPTIAEGTSLPTSTTSEGSTPLSIMPLSTTPVASSEASTLS-------TTPVDT 3485

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLT-LPNHEVSVQPPGED 288
               + +SS    +P                E  ++P  ++ E  T L N  VS  P    
Sbjct: 3486 STPVTTSSPTNSSPTTA-------------EVTSMPTSTAGEGSTPLTNMPVSTTPVASS 3532

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +A      ++  P D    +TS  +  + S    Q T ++     E S++     +    
Sbjct: 3533 EA----STLSTTPVDSNTFVTSS-SQASSSPATLQVTTMRMSTPSEGSSSLTTMLLSSTY 3587

Query: 349  PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408
                  ++ SE   P  PS       ++ TQ  +   PPE   + +S P    T     P
Sbjct: 3588 ------VTSSEASTPSTPSVDRSTPVTTSTQSNSTPTPPEVITLPMSTPSEVSTPLTIMP 3641

Query: 409  ----SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPL--L 462
                SV++       T+  + S  V TS     +     G+   +  P+   G  PL  +
Sbjct: 3642 VSTTSVTISEAGTASTLPVDTSTPVITSTQVSSSPVTPEGTTMPIWTPS--EGSTPLTTM 3699

Query: 463  PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH------------PQTAEEGE 510
            P S+          E S  S   +    P  T  EA +              P       
Sbjct: 3700 PVSTTRV----TSSEGSTLSTPSVVTSTPVTTSTEAISSSATLDSTTMSVSMPMEISTLG 3755

Query: 511  SSLTHQEAP------AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
            +++     P      + TP  P+V  +     +  ++ +  P  L  T T    T  E S
Sbjct: 3756 TTILVSTTPVTRFPESSTPSIPSVYTSM--SMTTASEGSSSPTTLEGTTTMPMSTTSERS 3813

Query: 565  PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP------SVTVQLLDLGLTIT 618
              +      P   + P     +  T  TP  D +   ++       S+  ++  + ++IT
Sbjct: 3814 TLLTTVLISPISVMSPS----EASTLSTPPGDTSTPLLTSTKAGSFSIPAEVTTIRISIT 3869

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
             E       STP    +VS      TLP      T     + A+  PLD   T TP + T
Sbjct: 3870 SE------RSTPLTTLLVS-----TTLP------TSFPGASIASTPPLDTSTTFTPSTDT 3912

Query: 679  EVEP--------STALMTTAPPPG------HPEVTLPPSDKGQAQHSHLTQATVQPLDLE 724
               P        S +++T    PG         VT   +D   A    ++   +   +L 
Sbjct: 3913 ASTPTIPVATTISVSVITEGSTPGTTIFIPSTPVTSSTADVFPATTGAVSTPVITSTELN 3972

Query: 725  LTITTKPTTEVKPSPTTEET----STQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
               T+  +T    S T E T    +T  P   + +   P+T    S     T+A      
Sbjct: 3973 TPSTSSSSTTTSFSTTKEFTTPAMTTAAPLTYVTMSTAPSTPRTTSRGC-TTSASTLSAT 4031

Query: 781  QTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEM 840
             T H S +  T P T   P+ +S   S   +     T P  H ++  T      T   E 
Sbjct: 4032 STPHTSTSVTTRPVT---PSSESSRPSTITSHTIPPTFPPAHSSTPPTTSASSTTVNPEA 4088

Query: 841  LSCIDLNPEQRLRQVPVPEPNT 862
            ++ +    +   R    P   T
Sbjct: 4089 VTTMTTRTKPSTRTTSFPTVTT 4110



 Score = 51.6 bits (122), Expect = 6e-06
 Identities = 76/352 (21%), Positives = 128/352 (36%), Gaps = 38/352 (10%)

Query: 477 ETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
           E+S  S  P +++   +PT+    +E    +     S T   +   TPE  +V ++ P E
Sbjct: 95  ESSVTSDTPGVSSTRMTPTESRTTSESTSDSTTLFPSSTEDTSSPTTPEGTDVPMSTPSE 154

Query: 536 HS-HLTQATVQPLDL-------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQG 587
            S   T A V    L         T   +  T +  S     +PT P    +P+    +G
Sbjct: 155 ESISSTMAFVSTAPLPSFEAYTSLTYKVDMSTPLTTSTQASSSPTTPESTTIPKSTNSEG 214

Query: 588 VTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH 647
            T P      +   V+ S  + LL   + I+   T     S+ P     + + P ++   
Sbjct: 215 ST-PLTSMPASTMKVASSEAITLLTTPVEISTPVTISAQASSSP----TTAEGPSLSNSA 269

Query: 648 PDQVQTQ------------HSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGH 695
           P    T              S  +  +  P      +   +     P+TA  T+ P   +
Sbjct: 270 PSGGSTPLTRMPLSVMLVVSSEASTLSTTPAATNIPVITSTEASSSPTTAEGTSIPTSTY 329

Query: 696 PEVTLP----PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
            E + P    P+       S ++  ++ P+D    +TT  +TE    PTT E ++     
Sbjct: 330 TEGSTPLTSTPASTMPVATSEMSTLSITPVDTSTLVTT--STEPSSLPTTAEATSMLTST 387

Query: 752 GLAIIPEPTTETGHSTAL-----EKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
            L+    P T    ST L       TT+  P   +T   + +E +  PT  E
Sbjct: 388 -LSEGSTPLTNMPVSTILVASSEASTTSTIPVDSKTFVTTASEASSSPTTAE 438


>gi|151301154 mucin 6, gastric [Homo sapiens]
          Length = 2439

 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 164/743 (22%), Positives = 234/743 (31%), Gaps = 125/743 (16%)

Query: 154  PAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPY-PGSLPPEL-RVKSDEPPGPSE 211
            P Q W +      I  LS+      +     S T TP  P +L        S EPP P+ 
Sbjct: 1217 PTQVWPMTGTSTTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSKPTASSGEPPRPTT 1276

Query: 212  QVGPSQFHLEPET---QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES 268
             V P      P T   ++  T   +  ++ +  A    P       S+ +       P +
Sbjct: 1277 AVTPQATSGLPPTATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTMTLPTPAT 1336

Query: 269  SMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTIT---SEPTNETESSQAQQET 325
            S  S TLP    + + PG        P  T  PA      T    +PT  T +   Q  T
Sbjct: 1337 SGTSPTLPK-STNQELPGTTATQTTGPRPT--PASTTGPTTPQPGQPTRPTATETTQTRT 1393

Query: 326  PIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSES------PREVESSPTQ 379
              ++     P  T        PVP      + S       P+ S      P  V    T 
Sbjct: 1394 TTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTYPTPSHPETTLPTHVPPFSTS 1453

Query: 380  QETPGQ----PPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVH 435
              TP       P H ++  S   H        P  ++K      T         GTS  H
Sbjct: 1454 LVTPSTHTVITPTHAQMATSASNHSAPTGTIPPPTTLKATGSTHTAPPITPTTSGTSQAH 1513

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGP-----------LAVQQETSFQSPE 484
               +T  + +       +  H  P + P S+    P                 TS + P 
Sbjct: 1514 SSFSTNKTPTSLHSHTSSTHH--PEVTPTSTTTITPNPTSTRTRTPVAHTNSATSSRPPP 1571

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTH-------QEAPAQTPEF------PNVVVA 531
            P    +P       ++  P TA   +++ T+          P   P F      P+    
Sbjct: 1572 PFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTV 1631

Query: 532  QPPEHSHL-TQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
              P H+ + T A++  +  G TI P    ++      +PTM  T T    + +  L   +
Sbjct: 1632 ITPTHAQMATSASIHSMPTG-TIPPPTTLKATGSTHTAPTMTLT-TSGTSQALSSLNTAK 1689

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIV---------- 636
              T+         H  + S +         ITP PT+     TPP               
Sbjct: 1690 TSTSLHSHTSSTHHAEATSTST------TNITPNPTST---GTPPMTVTTSGTSQSRSSF 1740

Query: 637  --------------SPKHPEVTLPHPDQVQTQH---------SHLTRATVQPLDLGFT-- 671
                          S  HPEVT      +   H         +H T AT   L   FT  
Sbjct: 1741 STAKTSTSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTH 1800

Query: 672  -----ITPKSMTEVEPSTALMTTA--PPPGHPEVTLP------------PSDKGQAQHSH 712
                  TP S T    +T+  TT   P P HP  TLP            PS       +H
Sbjct: 1801 SPPTGTTPISSTGPVTATSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTH 1860

Query: 713  LTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKT 772
               AT   +    T T  P T +K    T  T T PP   +      T+++  S +  KT
Sbjct: 1861 TQMATSASIHSMPTGTIPPPTTIK---ATGSTHTAPP---MTPTTSGTSQSPSSFSTAKT 1914

Query: 773  TAPRPDRVQTLHRSLTEVTGPPT 795
            +   P    + H    EVT   T
Sbjct: 1915 STSLPYHTSSTHH--PEVTPTST 1935



 Score = 80.9 bits (198), Expect = 9e-15
 Identities = 148/670 (22%), Positives = 227/670 (33%), Gaps = 140/670 (20%)

Query: 193  GSLPPELRVKSD-----EPPGPSEQVGPSQFHLEPET-QNPETLEDIQSSSLQQEAPAQL 246
            G++PP   +K+       PP      G SQ H    T + P +L    SS+   E     
Sbjct: 1482 GTIPPPTTLKATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTS 1541

Query: 247  PQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEV 306
               +   P+S +   P     S+  S   P       P G        P  +  P    +
Sbjct: 1542 TTTITPNPTSTRTRTPVAHTNSATSSRPPPPFTTHSPPTGSS------PFSSTGP----M 1591

Query: 307  TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQP 366
            T TS  T  T  + +  +T +  P  V P +T         V P  H +        + P
Sbjct: 1592 TATSFKTTTTYPTPSHPQTTL--PTHVPPFSTSL-------VTPSTHTV--------ITP 1634

Query: 367  SESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPS 426
            + +     +S     T   PP     T+   G   T    +P++++        +++  +
Sbjct: 1635 THAQMATSASIHSMPTGTIPPP---TTLKATGSTHT----APTMTLTTSGTSQALSSLNT 1687

Query: 427  AEVGTSLVHQEATTR----LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQS 482
            A+  TSL    ++T      S S  ++ P     G PP+   +S  +     Q  +SF +
Sbjct: 1688 AKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTS-----QSRSSFST 1742

Query: 483  PEPINNENPSPTQQEAAAEHPQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLT 540
             +     + S     ++  HP+      +S+T  H     +TP             +H T
Sbjct: 1743 AKT----STSLHSHTSSTHHPEVTSTSTTSITPNHTSTGTRTPV------------AHTT 1786

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN-PTPGQDQAQ 599
             AT   L   FT          +S T   T T            +Q  T  PTP      
Sbjct: 1787 SATSSRLPTPFTTHSPPTGTTPISSTGPVTATS-----------FQTTTTYPTPSHPHTT 1835

Query: 600  HPVS-PSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH------------PEVTLP 646
             P   PS +  L+                 TP   T++ P H            P  T+P
Sbjct: 1836 LPTHVPSFSTSLV-----------------TPSTHTVIIPTHTQMATSASIHSMPTGTIP 1878

Query: 647  HPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKG 706
             P  ++   S  T   + P   G + +P S +  + ST+L        HPEVT  P+   
Sbjct: 1879 PPTTIKATGSTHTAPPMTPTTSGTSQSPSSFSTAKTSTSLPYHTSSTHHPEVT--PTSTT 1936

Query: 707  QAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHS 766
                 H +  T  P    +  TT  ++   P+P T    T  P  G      P + TG  
Sbjct: 1937 NITPKHTSTGTRTP----VAHTTSASSSRLPTPFT----THSPPTG----SSPFSSTGPM 1984

Query: 767  TALE---KTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESY-----TQNKALTA 818
            TA      TT P P   QT           PT + P   SLV   ++     T  +  T+
Sbjct: 1985 TATSFQTTTTYPTPSHPQTT---------LPTHVPPFSTSLVTPSTHTVIITTHTQMATS 2035

Query: 819  PEEHKASTST 828
               H   T T
Sbjct: 2036 ASIHSTPTGT 2045



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 116/566 (20%), Positives = 184/566 (32%), Gaps = 101/566 (17%)

Query: 325  TPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPG 384
            T I       PS +    P  P   P+      S +  P   S  P    ++ T Q T G
Sbjct: 1228 TTIGLLSSTGPSPSSNHTPASPTQTPLLPATLTSSK--PTASSGEPPRPTTAVTPQATSG 1285

Query: 385  QPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             PP                     S + KP   Q T  A  S     +    ++TTR + 
Sbjct: 1286 LPPT----------------ATLRSTATKPTVTQATTRATASTASPATTSTAQSTTRTTM 1329

Query: 445  SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
            +     P     G  P LP+S+ +  P     +T+   P P            A+   P 
Sbjct: 1330 T----LPTPATSGTSPTLPKSTNQELPGTTATQTTGPRPTP------------ASTTGPT 1373

Query: 505  TAEEG--------ESSLTHQEAPAQTPEFPNVVVAQP----------------------- 533
            T + G        E++ T       TP+ P+   + P                       
Sbjct: 1374 TPQPGQPTRPTATETTQTRTTTEYTTPQTPHTTHSPPTAGSPVPSTGPVTATSFHATTTY 1433

Query: 534  --PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNP 591
              P H   T  T  P      +TP + T +  +PT  +  T       P   +    T  
Sbjct: 1434 PTPSHPETTLPTHVPPFSTSLVTPSTHTVI--TPTHAQMATSASNHSAPTGTIPPPTTLK 1491

Query: 592  TPGQDQAQHPVSPSVT-VQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
              G      P++P+ +         +    PT+   H++      V+P       P+P  
Sbjct: 1492 ATGSTHTAPPITPTTSGTSQAHSSFSTNKTPTSLHSHTSSTHHPEVTPTSTTTITPNPTS 1551

Query: 651  VQTQH--SHLTRATVQPLDLGFTI-------TPKSMTEVEPSTALMTTA--PPPGHPEVT 699
             +T+   +H   AT       FT        +P S T    +T+  TT   P P HP+ T
Sbjct: 1552 TRTRTPVAHTNSATSSRPPPPFTTHSPPTGSSPFSSTGPMTATSFKTTTTYPTPSHPQTT 1611

Query: 700  LP-------PSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLG 752
            LP        S    + H+ +T    Q +    +I + PT  + P  T + T +      
Sbjct: 1612 LPTHVPPFSTSLVTPSTHTVITPTHAQ-MATSASIHSMPTGTIPPPTTLKATGSTHTAPT 1670

Query: 753  LAIIPEPTTETGHSTALEKTTAPRPDRVQTLHR------SLTEVTGPPTELEPAQDSLVQ 806
            + +    T++   S    KT+        + H       S T +T  PT       ++  
Sbjct: 1671 MTLTTSGTSQALSSLNTAKTSTSLHSHTSSTHHAEATSTSTTNITPNPTSTGTPPMTVTT 1730

Query: 807  S------ESYTQNKALTAPEEHKAST 826
            S       S++  K  T+   H +ST
Sbjct: 1731 SGTSQSRSSFSTAKTSTSLHSHTSST 1756



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 122/611 (19%), Positives = 211/611 (34%), Gaps = 89/611 (14%)

Query: 171  STPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETL 230
            S+P S    +      T T YP    P+  + +  PP  +  V PS   +      P   
Sbjct: 1582 SSPFSSTGPMTATSFKTTTTYPTPSHPQTTLPTHVPPFSTSLVTPSTHTVI----TPTHA 1637

Query: 231  EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN---HEVSVQPPGE 287
            +   S+S+       +P     + +     AP +   +S  S  L +    + S      
Sbjct: 1638 QMATSASIHSMPTGTIPPPTTLKATGSTHTAPTMTLTTSGTSQALSSLNTAKTSTSLHSH 1697

Query: 288  DQAYYHLP-------NITVKPADV---EVTITSEPTNETESSQAQQETPIQFPE------ 331
              + +H         NIT  P       +T+T+  T+++ SS +  +T            
Sbjct: 1698 TSSTHHAEATSTSTTNITPNPTSTGTPPMTVTTSGTSQSRSSFSTAKTSTSLHSHTSSTH 1757

Query: 332  --EVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP 386
              EV  ++T    P         P+ H  S +  + P   +       ++P     P   
Sbjct: 1758 HPEVTSTSTTSITPNHTSTGTRTPVAHTTSATSSRLPTPFTTHSPPTGTTPISSTGPVTA 1817

Query: 387  PEHHEVTVSP-PGHHQTH---HLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRL 442
                  T  P P H  T    H+ S S S+  P     I    +    ++ +H   T  +
Sbjct: 1818 TSFQTTTTYPTPSHPHTTLPTHVPSFSTSLVTPSTHTVIIPTHTQMATSASIHSMPTGTI 1877

Query: 443  SGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH 502
                  ++     H  PP+ P +S  +     Q  +SF + +     + S     ++  H
Sbjct: 1878 PPP-TTIKATGSTHTAPPMTPTTSGTS-----QSPSSFSTAKT----STSLPYHTSSTHH 1927

Query: 503  PQTAEEGESSLT--HQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTI------- 553
            P+      +++T  H     +TP             +H T A+   L   FT        
Sbjct: 1928 PEVTPTSTTNITPKHTSTGTRTPV------------AHTTSASSSRLPTPFTTHSPPTGS 1975

Query: 554  TPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL 613
            +P S T   ++ T  +T T  P    PQ       T PT     +   V+PS    ++  
Sbjct: 1976 SPFSSTG-PMTATSFQTTTTYPTPSHPQ------TTLPTHVPPFSTSLVTPSTHTVIIT- 2027

Query: 614  GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTIT 673
              T T   T+   HSTP             T+P P  ++   S  T   +     G + T
Sbjct: 2028 --THTQMATSASIHSTPTG-----------TVPPPTTLKATGSTHTAPPMTVTTSGTSQT 2074

Query: 674  PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
              S +    S++ ++++        + PPS     Q  HL+ AT       ++ T + ++
Sbjct: 2075 HSSFSTATASSSFISSSSWLPQNSSSRPPSSPITTQLPHLSSATT-----PVSTTNQLSS 2129

Query: 734  EVKPSPTTEET 744
               PSP+   T
Sbjct: 2130 SFSPSPSAPST 2140


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 84.0 bits (206), Expect = 1e-15
 Identities = 166/735 (22%), Positives = 232/735 (31%), Gaps = 109/735 (14%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3729 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3784

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3785 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3828

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3829 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3879

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3934

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3935 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3990

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3991 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4050

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 4051 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4104

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4105 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4151

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSH----LTRATVQPLDLGFTITPKSMTEVEPSTALM 687
               I +      T P P   QT  +      T  T  P   G    P + T   P   L 
Sbjct: 4152 TTPITTTTTVTPT-PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAELT 4210

Query: 688  TTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQ----PLDLELTITTKPTTEVKPSPTTEE 743
            T+ PPP   E + P + +  +  S LT++T      P  +E+T T  P+T   P+ T+  
Sbjct: 4211 TSNPPP---ESSTPQTSRSTS--SPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGG 4265

Query: 744  TSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPP--------- 794
             +  PP       P  T   G +T    ++AP P  VQT   S    T  P         
Sbjct: 4266 HTLSPPP-STTTSPPGTPTRGTTTG--SSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRT 4322

Query: 795  TELEPAQDSLVQSESYTQNKALTAP-EEHKASTSTNICELCTCGDEMLSCIDLNPEQRLR 853
            T L P   S++       N    AP EE    T  + C    C    LSC          
Sbjct: 4323 TGLRPYPSSVL--ICCVLNDTYYAPGEEVYNGTYGDTCYFVNCS---LSCTLEFYNWSCP 4377

Query: 854  QVPVPEPNTHNGTFT 868
              P P P     T T
Sbjct: 4378 STPSPTPTPSKSTPT 4392



 Score = 81.6 bits (200), Expect = 6e-15
 Identities = 128/501 (25%), Positives = 158/501 (31%), Gaps = 109/501 (21%)

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            P D  +T  S PT           T    P    PS         PP       ++ +  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTT---LPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
              P      P    ++P    TP  P      T SPP    T   + P+ +   P    T
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPT----TTPSPP----TTTPSPPTTTTTTPPPTTT 1499

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSF 480
                PS    T +    +TT L  +     P       PP    S     P+     TS 
Sbjct: 1500 ----PSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT--PPTST 1553

Query: 481  QSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT 540
             +  P    +P PT                   T    P  TP  P      PP    +T
Sbjct: 1554 TTLPPTTTPSPPPTT------------------TTTPPPTTTPSPPTTTTPSPPT---IT 1592

Query: 541  QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
              T  P     T TP        SP    T T PP             T P+P       
Sbjct: 1593 TTTPPP-----TTTP--------SPPTTTTTTPPP------------TTTPSP---PTTT 1624

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P++P  +   L    T +P PTT    +TPP  T  SP  P  T P P         +T 
Sbjct: 1625 PITPPTSTTTLPPTTTPSPPPTTT---TTPPPTTTPSP--PTTTTPSPP--------ITT 1671

Query: 661  ATVQPLDLGFTITPKS--MTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATV 718
             T  P     T TP S   T   P T  MTT      P  T  PS       S +T  T 
Sbjct: 1672 TTTPPP----TTTPSSPITTTPSPPTTTMTT------PSPTTTPS-------SPITTTTT 1714

Query: 719  QPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPD 778
                   T +  PTT   PSPT   T+  PP   +  +P PTT     T+   TT P P 
Sbjct: 1715 P--SSTTTPSPPPTTMTTPSPT---TTPSPPTTTMTTLP-PTT-----TSSPLTTTPLPP 1763

Query: 779  RVQTLHRSLTEVTGPPTELEP 799
             +     S    T P T   P
Sbjct: 1764 SITPPTFSPFSTTTPTTPCVP 1784



 Score = 78.2 bits (191), Expect = 6e-14
 Identities = 92/372 (24%), Positives = 121/372 (32%), Gaps = 35/372 (9%)

Query: 459  PPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEA 518
            PP  P S+    P       +  +  P     PSP         P T      S T    
Sbjct: 1408 PP--PTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 519  PAQTPEFPNVVVAQP---PEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKET---PT 572
            P  TP  P    + P   P     T  T  P     T TP   T   ++P    T   PT
Sbjct: 1466 PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPP-----TTTPSPPTTTPITPPASTTTLPPT 1520

Query: 573  QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGH---ST 629
              P             T P+P       P++P  +   L    T +P PTT       +T
Sbjct: 1521 TTPSPPTTTTTTPPPTTTPSP---PTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT 1577

Query: 630  PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT- 688
            P   T  +P  P +T   P    T     T  T  P     T +P + T + P T+  T 
Sbjct: 1578 PSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTL 1635

Query: 689  ---TAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
               T P P     T PP     +  +     T  P     T TT P T    SP T  T+
Sbjct: 1636 PPTTTPSPPPTTTTTPPPTTTPSPPT-----TTTPSPPITTTTTPPPTTTPSSPIT--TT 1688

Query: 746  TQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
              PP   +   P PTT    S+ +  TT P      +   +      P T   P   ++ 
Sbjct: 1689 PSPPTTTMTT-PSPTTTP--SSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMT 1745

Query: 806  QSESYTQNKALT 817
                 T +  LT
Sbjct: 1746 TLPPTTTSSPLT 1757



 Score = 75.9 bits (185), Expect = 3e-13
 Identities = 82/289 (28%), Positives = 98/289 (33%), Gaps = 30/289 (10%)

Query: 522  TPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQ 581
            TP  P    + PP  +     T  P     T T    T     P    T T PP    P 
Sbjct: 1398 TPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPIT--TTTTPPPTTTPS 1455

Query: 582  LRVYQGVTNP-TPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKH 640
              +    T P T          SP  T        T TP PTT     +PP  T ++P  
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT---PSPPTTTPITPPA 1512

Query: 641  PEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMT----TAPPPGHP 696
               TLP      T     T  T  P     T +P + T + P T+  T    T P P   
Sbjct: 1513 STTTLP---PTTTPSPPTTTTTTPPPTT--TPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 697  EVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAII 756
              T PP     +  +     T  P    +T TT P T   PSP T  T+T PP       
Sbjct: 1568 TTTTPPPTTTPSPPT-----TTTPSPPTITTTTPPPTTT-PSPPTTTTTTPPP----TTT 1617

Query: 757  PEPTTETG-----HSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPA 800
            P P T T       +T L  TT P P    T     T    PPT   P+
Sbjct: 1618 PSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPS 1666



 Score = 75.1 bits (183), Expect = 5e-13
 Identities = 157/697 (22%), Positives = 213/697 (30%), Gaps = 113/697 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3660 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3715

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3716 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3759

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3760 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3810

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3865

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3866 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3921

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3922 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3981

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3982 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 4035

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 4036 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 4082

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 4083 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 4131

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL 751
                  VT  P+  G          T  P    +T TT  T    P+PT  +T T  P  
Sbjct: 4132 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTP-- 4177

Query: 752  GLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYT 811
                I   TT T   T     T P P    T   +    + PP E    Q S   S   T
Sbjct: 4178 ----ITTTTTVTPTPTPTGTQTGP-PTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLT 4232

Query: 812  QNKALTA---PEEHKAST---STNICELCTCGDEMLS 842
            ++  L +   P     ST   ST      T G   LS
Sbjct: 4233 ESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLS 4269



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 167/745 (22%), Positives = 225/745 (30%), Gaps = 111/745 (14%)

Query: 186  STDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
            +T T  P +  P   + +   P P+    P      P T  P       ++      P+ 
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSP 1502

Query: 246  LPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVE 305
                    P+S     P   P     + T P    +  PP            T+ P    
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP---- 1558

Query: 306  VTITSEPTNETESSQAQQETPIQFPEEVEPS----ATQQEAPIEPPVPPMEHELSISEQQ 361
             T T  P   T ++     TP   P    PS     T    P   P PP     +     
Sbjct: 1559 -TTTPSPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTT 1616

Query: 362  QPVQPSESPREVESSPTQ---QETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQ 418
             P  P+ +P    +S T      TP  PP     T +PP          P+ +  PP   
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPT---TTTTPP----------PTTTPSPPTT- 1662

Query: 419  LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
                  PS  + T+      TT  S       PP      P      S           T
Sbjct: 1663 ----TTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSST 1718

Query: 479  SFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSH 538
            +  SP P     PSPT   +    P T        T   +P  T   P  +   PP  S 
Sbjct: 1719 TTPSPPPTTMTTPSPTTTPS----PPTTTMTTLPPTTTSSPLTTTPLPPSIT--PPTFSP 1772

Query: 539  LTQATVQP-----------LDLGFTITPESKTEVEL---------SPTMKETPTQPPKKV 578
             +  T              LD G     +   + EL         +  +    T  P   
Sbjct: 1773 FSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVP 1832

Query: 579  VPQLRVYQGVTNPTPG-----QDQAQHPVSP-------SVTVQLLDLGLTITPEPTTEVG 626
            + QL     V + + G     +DQ    V P        + VQ  +     T   TT   
Sbjct: 1833 IGQLG-QTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTE 1891

Query: 627  HSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
            + TPP  T ++        P P   QT        T  P+    T+TP   T     T  
Sbjct: 1892 NPTPPTTTPITTTTTVTPTPTPTGTQT-------PTTTPITTTTTVTP---TPTPTGTQT 1941

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSH---LTQATVQPLDLEL---TITTKP---TTEVKP 737
             TT P      VT  P+  G    +     T  TV P        T TT P   TT V P
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2001

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2062 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2113

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2114 VTPTPTPTGTQTPTTTPITTTTTVT 2138



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2004 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2059

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2060 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2103

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2104 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2154

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2155 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2209

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2210 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2265

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2266 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2325

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2326 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2379

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2380 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2426

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2427 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2475

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2476 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2523

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2583

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2584 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2635

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2636 PITTTTTVT 2644



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2119 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2174

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2175 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2218

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2219 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2269

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2270 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2324

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2325 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2380

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2381 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2440

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2441 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2494

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2495 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2541

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2542 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2590

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2591 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2638

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2698

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2699 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2750

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2751 PITTTTTVT 2759



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2234 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2289

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2290 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2333

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2334 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2384

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2385 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2439

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2495

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2496 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2555

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2556 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2609

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2610 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2656

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2657 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2705

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2706 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2753

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2813

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2814 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2865

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2866 PITTTTTVT 2874



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2349 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2404

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2405 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2448

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2449 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2499

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2554

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2610

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2611 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2670

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2671 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2724

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2725 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2771

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2772 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2820

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2821 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2868

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 2928

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 2929 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 2980

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 2981 PITTTTTVT 2989



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2464 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2519

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2520 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2563

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2564 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2614

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2615 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2669

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2670 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2725

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2726 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2785

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2786 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2839

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2840 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 2886

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 2887 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 2935

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 2936 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 2983

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3043

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3044 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3095

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3096 PITTTTTVT 3104



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2579 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2634

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2635 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2678

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2679 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2729

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2730 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2784

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2785 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2840

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2841 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2900

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 2901 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 2954

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 2955 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3001

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3002 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3050

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3051 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3098

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3158

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3159 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3210

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3211 PITTTTTVT 3219



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2694 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2749

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2750 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2793

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2794 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2844

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 2899

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 2955

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 2956 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3015

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3016 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3069

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3070 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3116

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3117 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3165

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3166 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3213

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3273

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3274 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3325

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3326 PITTTTTVT 3334



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2809 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2864

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2865 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 2908

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 2909 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 2959

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 2960 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3014

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3070

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3071 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3130

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3131 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3184

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3185 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3231

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3232 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3280

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3281 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3328

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3388

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3389 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3440

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3441 PITTTTTVT 3449



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 2924 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 2979

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 2980 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3023

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3024 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3074

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3075 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3129

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3130 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3185

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3186 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3245

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3246 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3299

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3300 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3346

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3347 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3395

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3396 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3443

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3503

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3504 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3555

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3556 PITTTTTVT 3564



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3039 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3094

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3095 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3138

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3139 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3189

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3244

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3245 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3300

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3301 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3360

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3361 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3414

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3415 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3461

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3462 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3510

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3511 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3558

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3618

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3619 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3670

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3671 PITTTTTVT 3679



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 161/729 (22%), Positives = 223/729 (30%), Gaps = 120/729 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            TP   +       ++T T  P   P   +  +  P   +  V P+       TQ P T  
Sbjct: 3154 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP--TPTGTQTPTT-- 3209

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                       P      +   P+    + P   P ++  ++T        Q P      
Sbjct: 3210 ----------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------ 3253

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  T  P     T+T  PT     +Q    TPI     V P+ T       P   P+
Sbjct: 3254 ------TTTPITTTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPI 3304

Query: 352  EHELSISEQQQPV---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQT 402
                +++    P     P+ +P    ++      PT  +TP   P     TV+P     T
Sbjct: 3305 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----T 3359

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PP 460
                        P    T         GT    Q  TT    +   V P     G   P 
Sbjct: 3360 PTPTGTQTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPT 3415

Query: 461  LLP-ESSEEAGPLAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL- 513
              P  ++    P      T   +  PI         P+PT  +     P T     +   
Sbjct: 3416 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3475

Query: 514  --THQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
              T  + P  TP      V   P  +     T  P+    T+TP        +PT  +TP
Sbjct: 3476 TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTP 3529

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            T  P      +        PTP     Q P +  +T        T+TP PT   G  TP 
Sbjct: 3530 TTTPITTTTTV-------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPT 3576

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
               I +      T P P   QT        T  P+    T+TP   T     T   TT P
Sbjct: 3577 TTPITTTTTVTPT-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTP 3625

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPD 750
                  VT  P+  G          T  P    +T TT  T    P+PT  +T +T P  
Sbjct: 3626 ITTTTTVTPTPTPTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPIT 3673

Query: 751  LGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEP 799
                + P PT   T+T  +T +  TT     P P   QT       + T VT  PT    
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT 3733

Query: 800  AQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPE 859
               +     + T       P   +  T+T I    T        +   P     Q P   
Sbjct: 3734 QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTT 3785

Query: 860  PNTHNGTFT 868
            P T   T T
Sbjct: 3786 PITTTTTVT 3794



 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 158/717 (22%), Positives = 223/717 (31%), Gaps = 108/717 (15%)

Query: 185  SSTDTPYPGSLPPELRVKSDEP-PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAP 243
            ++T+ P P +  P     +  P P P+    P+   +   T    T     + +     P
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTP 1946

Query: 244  AQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPAD 303
                  +   P+    + P   P ++  ++T        Q P            T  P  
Sbjct: 1947 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP------------TTTPIT 1994

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP 363
               T+T  PT     +Q    TPI     V P+ T       P   P+    +++    P
Sbjct: 1995 TTTTVTPTPT--PTGTQTPTTTPITTTTTVTPTPTPTGTQT-PTTTPITTTTTVTPTPTP 2051

Query: 364  V---QPSESPREVESS------PTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKP 414
                 P+ +P    ++      PT  +TP   P     TV+P     T            
Sbjct: 2052 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP-----TPTPTGTQTPTTT 2106

Query: 415  PDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGG--PPLLP-ESSEEAGP 471
            P    T         GT    Q  TT    +   V P     G   P   P  ++    P
Sbjct: 2107 PITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2162

Query: 472  LAVQQETSFQSPEPINNEN-----PSPTQQEAAAEHPQTAEEGESSL---THQEAPAQTP 523
                  T   +  PI         P+PT  +     P T     +     T  + P  TP
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222

Query: 524  EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR 583
                  V   P  +     T  P+    T+TP        +PT  +TPT  P      + 
Sbjct: 2223 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP------TPTGTQTPTTTPITTTTTV- 2275

Query: 584  VYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEV 643
                   PTP     Q P +  +T        T+TP PT   G  TP    I +      
Sbjct: 2276 ------TPTPTPTGTQTPTTTPITTTT-----TVTPTPTP-TGTQTPTTTPITTTTTVTP 2323

Query: 644  TLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPS 703
            T P P   QT        T  P+    T+TP   T     T   TT P      VT  P+
Sbjct: 2324 T-PTPTGTQTP-------TTTPITTTTTVTP---TPTPTGTQTPTTTPITTTTTVTPTPT 2372

Query: 704  DKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-STQPPDLGLAIIPEPT-- 760
              G          T  P    +T TT  T    P+PT  +T +T P      + P PT  
Sbjct: 2373 PTG----------TQTPTTTPITTTT--TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2420

Query: 761  -TETGHSTALEKTT----APRPDRVQTLH----RSLTEVTGPPTELEPAQDSLVQSESYT 811
             T+T  +T +  TT     P P   QT       + T VT  PT       +     + T
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480

Query: 812  QNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFT 868
                   P   +  T+T I    T        +   P     Q P   P T   T T
Sbjct: 2481 TVTPTPTPTGTQTPTTTPITTTTT--------VTPTPTPTGTQTPTTTPITTTTTVT 2529



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 160/745 (21%), Positives = 226/745 (30%), Gaps = 94/745 (12%)

Query: 170  LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPET 229
            ++TP     T     +ST T  P + P      +  PP  +    PS       T  P T
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPITTTTTPPPTT 1452

Query: 230  LEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQ 289
                  S+     P   P      P +     P   P     + T P    +  PP    
Sbjct: 1453 TPSPPISTTTTPPPTTTPS-----PPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTP 1507

Query: 290  -----AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPI 344
                 +   LP  T        T T  PT           TP      + P+ T    P 
Sbjct: 1508 ITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 345  EPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
                PP       +    P   + SP  + ++     T   PP     T +PP    T  
Sbjct: 1568 TTTTPP-----PTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPT--TTTTTPP--PTTTP 1618

Query: 405  LASPSVSVKPPDVQLTI--AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
                +  + PP    T+     PS    T+      TT          PP      PP+ 
Sbjct: 1619 SPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTT--------PSPPTTTTPSPPIT 1670

Query: 463  PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
              ++           T+  SP       PSPT   ++   P T     SS T    P  T
Sbjct: 1671 TTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSS---PITTTTTPSSTTTPSPPPTT 1727

Query: 523  PEFPNVVVAQPPEHSHLT--QATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVP 580
               P+      P  + +T    T     L  T  P S T    SP    TPT P    VP
Sbjct: 1728 MTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP---CVP 1784

Query: 581  QLRVYQGVTNPTP------GQDQAQHPVSPSVTVQLLDLGLTITPE-PTTEVGHSTPPKR 633
                   + +  P      G  +    V        +    T+ P+ P  ++G +     
Sbjct: 1785 LCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVCDV 1844

Query: 634  TI-----VSPKHPEVTLPHPDQVQTQ-HSHLTRATVQPLDLGFTIT----PKSMTEVEPS 683
            ++        + P   +P    +  + +        QP  +  T T    P + T +  +
Sbjct: 1845 SVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPTPPTTTPITTT 1904

Query: 684  TALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLEL---TITTKP---TTEVKP 737
            T +  T  P G    T  P           T  TV P        T TT P   TT V P
Sbjct: 1905 TTVTPTPTPTGTQTPTTTPI---------TTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 1955

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 1956 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2015

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2016 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2067

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2068 VTPTPTPTGTQTPTTTPITTTTTVT 2092



 Score = 55.5 bits (132), Expect = 4e-07
 Identities = 187/865 (21%), Positives = 256/865 (29%), Gaps = 163/865 (18%)

Query: 46   PLQLTSNP---LGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
            P+  T+ P     P  P S+ ++  P  +P  PT            PS  +  P+PP  +
Sbjct: 1441 PITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTT----------PSPPTTTPSPPTTT 1490

Query: 103  TENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAE 162
            T    P   T       P+ P     +         P       P      P     +  
Sbjct: 1491 TTTPPP-TTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI-- 1547

Query: 163  IIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEP 222
                     TP +   TL    + +  P   + PP         P P     PS   +  
Sbjct: 1548 ---------TPPTSTTTLPPTTTPSPPPTTTTTPPPTTT-----PSPPTTTTPSPPTITT 1593

Query: 223  ETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSV 282
             T  P T     +++     P   P        S     P  PP S   + TLP      
Sbjct: 1594 TTPPPTTTPSPPTTTTTTPPPTTTP--------SPPTTTPITPPTS---TTTLPPTTTPS 1642

Query: 283  QPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEA 342
             PP            T        T  S PT  T S       PI       P+ T    
Sbjct: 1643 PPP------------TTTTTPPPTTTPSPPTTTTPS------PPITTTTTPPPTTTPSSP 1684

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQT 402
                P PP     +      P     SP    ++P+   TP  PP     T++ P     
Sbjct: 1685 ITTTPSPP----TTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP----TTMTTP----- 1731

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
                SP+ +  PP   +T    P     + L     TT L  S   + PP      P   
Sbjct: 1732 ----SPTTTPSPPTTTMTTL--PPTTTSSPL----TTTPLPPS---ITPPTF---SPFST 1775

Query: 463  PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
               +    PL         S +P  ++    T+       P  A              + 
Sbjct: 1776 TTPTTPCVPLC-NWTGWLDSGKPNFHKPGGDTELIGDVCGPGWA---------ANISCRA 1825

Query: 523  PEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESK-----------TEVELSPTMKETP 571
              +P+V + Q      L Q  V  + +G     E +              E++    E  
Sbjct: 1826 TMYPDVPIGQ------LGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECV 1879

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
            TQP           +  T PT         V+P+ T        T TP  TT     TP 
Sbjct: 1880 TQPTTMTT---TTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTT-TPITTTTTVTPTPT 1935

Query: 632  KRTIVSPKHPEVT-----LPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTAL 686
                 +P    +T      P P    TQ       T  P+    T+TP   T     T  
Sbjct: 1936 PTGTQTPTTTPITTTTTVTPTPTPTGTQ-----TPTTTPITTTTTVTP---TPTPTGTQT 1987

Query: 687  MTTAPPPGHPEVTLPPSDKGQAQHSH---LTQATVQPLDLEL---TITTKP---TTEVKP 737
             TT P      VT  P+  G    +     T  TV P        T TT P   TT V P
Sbjct: 1988 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP 2047

Query: 738  SPT---TEETSTQPPDLGLAIIPEPT---TETGHSTALEKTT----APRPDRVQTLH--- 784
            +PT   T+  +T P      + P PT   T+T  +T +  TT     P P   QT     
Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2107

Query: 785  -RSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSC 843
              + T VT  PT       +     + T       P   +  T+T I    T        
Sbjct: 2108 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT-------- 2159

Query: 844  IDLNPEQRLRQVPVPEPNTHNGTFT 868
            +   P     Q P   P T   T T
Sbjct: 2160 VTPTPTPTGTQTPTTTPITTTTTVT 2184



 Score = 39.7 bits (91), Expect = 0.024
 Identities = 33/111 (29%), Positives = 44/111 (39%), Gaps = 10/111 (9%)

Query: 720  PLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
            P+D  +T  + PTT   P PT+  T+T PP       P P T T  +T    TT P P  
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTS--TTTLPP----TTTPSPPTTT--TTTPPPTTTPSPPI 1442

Query: 780  VQTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEEHKASTST 828
              T     T    PP  T   P   +     + T +   T P     +T+T
Sbjct: 1443 TTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTT 1493


>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
          Length = 825

 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 173/730 (23%), Positives = 268/730 (36%), Gaps = 131/730 (17%)

Query: 132 DLKDKLSPQERLPVSPK-KLKKDPAQRWSLAEIIGIIRQLSTPQSQK-QTLQNEYSSTDT 189
           +L + +   E  P  P  +LK D +Q+ S     G    ++ P  +K    Q  Y S   
Sbjct: 107 ELPESVQDVEIPPNIPSVQLKMDRSQQTSRT---GYWTMMNIPPVEKVDKEQQTYFSESE 163

Query: 190 PYPGSLPPELRVKSDEPPGPSEQVGP----SQFHLEPETQNPETL--EDIQSSSLQQEAP 243
               S P     KS E     +  G          +P T + E +  ++I  +S  QE  
Sbjct: 164 IVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQKNISRTSFTQETK 223

Query: 244 AQLPQLLEEEPSS-----MQQEAPALPPESSMESLTLPNHE---VSVQPPGEDQAYYHLP 295
              P LLE+E        + QE  A+   +S E +  P+ E     +QPP  ++A     
Sbjct: 224 KGPPVLLEDELREEVTVPVVQEGSAVKKVASAE-IEPPSTEKFPAKIQPPLVEEATAKAE 282

Query: 296 NITVKPADVEVTITSEPTNETESSQAQQETPI--QFPEEVEPSATQQEAPIEPPVPPMEH 353
               +   V+V  ++E T + E++ A  E  +  Q P   E    +  A I+PP      
Sbjct: 283 PRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPPSAEESP 342

Query: 354 ELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK 413
            + +  +  P    ESP E    P  +  P  PP     +V   G      + SPS    
Sbjct: 343 SVELLAEILPPSAEESPSE---EPPAEILP--PPAEKSPSVELLGE-----IRSPSAQKA 392

Query: 414 PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQH---GGPPLLPESSEEAG 470
           P +VQ  + AE + E        EA  +       VEPP ++       PLLPE +    
Sbjct: 393 PIEVQ-PLPAEGALE--------EAPAK-------VEPPTVEETLADVQPLLPEEAPREE 436

Query: 471 PLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVV 530
              +Q  T+ ++P        +PT+ ++      TAEE  +            E   +  
Sbjct: 437 ARELQLSTAMETPA-----EEAPTEFQSPLPKETTAEEASA------------EIQLLAA 479

Query: 531 AQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTN 590
            +PP      +A   PL    T   E+  EV+ SP  +ET  +     +  L   +   +
Sbjct: 480 TEPPADETPAEAR-SPLSEE-TSAEEAHAEVQ-SPLAEETTAEEASAEIQLLAAIEAPAD 536

Query: 591 PTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
            TP +  AQ P+S   + +          E   EV     P    VS +   + L  P  
Sbjct: 537 ETPAE--AQSPLSEETSAE----------EAPAEV---QSPSAKGVSIEEAPLELQPPSG 581

Query: 651 VQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTA---PPPGHP---EVTLPPSD 704
            +T     + A +Q L        ++  EV+P  A    A   PPP      EV  PP++
Sbjct: 582 EETTAEEAS-AAIQLLAATEASAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAE 640

Query: 705 KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPP---DLGLAIIPEPT 760
           +  A+        VQP   E     +   EV+P P  E     QPP   +    +   P 
Sbjct: 641 EAPAE--------VQPPPAE-----EAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQSLPA 687

Query: 761 TETGHSTALEKTTAPRPDRVQTLHRSL---------------------TEVTGPPTELEP 799
            ET     L    +P  D V     S+                      EV+ PP+E  P
Sbjct: 688 EETPIEETLAAVHSPPADDVPAEEASVDKHSPPADLLLTEEFPIGEASAEVSPPPSEQTP 747

Query: 800 AQDSLVQSES 809
             ++LV++ S
Sbjct: 748 EDEALVENVS 757



 Score = 48.5 bits (114), Expect = 5e-05
 Identities = 85/339 (25%), Positives = 135/339 (39%), Gaps = 59/339 (17%)

Query: 92  SSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPK--- 148
           S+ M  P +E+       L    +A E   E  Q LA+ +   D+   + R P+S +   
Sbjct: 443 STAMETPAEEAPTEFQSPLPKETTAEEASAEI-QLLAATEPPADETPAEARSPLSEETSA 501

Query: 149 -----KLKKDPAQRWSLAEIIGIIRQLS--------TPQSQKQTLQNEYSSTDTPYPGSL 195
                +++   A+  +  E    I+ L+        TP   +  L  E S+ + P     
Sbjct: 502 EEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPAEAQSPLSEETSAEEAPAEVQS 561

Query: 196 PPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL-PQLLEEEP 254
           P    V  +E P   +     +   E  +   + L   ++S+  +EAPA++ P   EE P
Sbjct: 562 PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASA--EEAPAEVQPPPAEEAP 619

Query: 255 SSMQ----QEAPA--LPP---ESSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPAD 303
           + +Q    +EAPA   PP   E+  E    P  E    VQPP  ++A          PA+
Sbjct: 620 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEA----------PAE 669

Query: 304 VEVTITSEPTNETESSQAQQETPIQF--------PEEVEPSATQQEAPIEPPVPP----M 351
           V+     E   E +S  A +ETPI+         P +  P+   +EA ++   PP    +
Sbjct: 670 VQPPPAEEAPAEVQSLPA-EETPIEETLAAVHSPPADDVPA---EEASVDKHSPPADLLL 725

Query: 352 EHELSISEQQQPVQ--PSESPREVESSPTQQETPGQPPE 388
             E  I E    V   PSE   E E+      T  Q P+
Sbjct: 726 TEEFPIGEASAEVSPPPSEQTPEDEALVENVSTEFQSPQ 764


>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
          Length = 2089

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 186/882 (21%), Positives = 302/882 (34%), Gaps = 114/882 (12%)

Query: 21   PWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPE--PWSSHSSHFPRESPHAPTLP 78
            PW +L  Q   L   E    +     L+     L PP   P   H      ESP    + 
Sbjct: 746  PWEVLATQPFCLRESEDSETQPFDTHLEAYGPCLSPPRAIPGDQHP-----ESP----VH 796

Query: 79   ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLS 138
             +P      G     ++   P+E+ E + P        G L  E E+ L  +Q     ++
Sbjct: 797  TEPMGIQGRGRQTVDKVMGIPKETAERVGP------ERGPLERETEKLLPERQT---DVT 847

Query: 139  PQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
             +E L     K K+D  Q+  LA      R     +S K    N  S++      SL  E
Sbjct: 848  GEEELT----KGKQDREQKQLLA------RDTQRQESDK----NGESASPERDRESLKVE 893

Query: 199  LRVKSD-EPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL----PQLLEEE 253
            +    + +     +Q  PS+   E E + P    +   + L+++ P  +     Q  E E
Sbjct: 894  IETSEEIQEKQVQKQTLPSKA-FEREVERPVANRECDPAELEEKVPKVILERDTQRGEPE 952

Query: 254  PSSMQQ--EAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSE 311
              S  Q  +A +  PE  + +  LP    +  P G        P    +     +     
Sbjct: 953  GGSQDQKGQASSPTPEPGVGAGDLPGPTSAPVPSGSQSGGRGSPVSPRRHQKGLLNCKMP 1012

Query: 312  PTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPR 371
            P  +    +A ++  +   ++  P A       E P PP +   S S++     P  SP 
Sbjct: 1013 PAEKASRIRAAEK--VSRGDQESPDACLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPL 1070

Query: 372  EVESSPT--------QQETPGQPPEHHEVTVSPPGHHQTHHLAS----PSVSVKPPDVQL 419
                 PT         QE P  P         P    +T   +     P+ S  P     
Sbjct: 1071 LPSIKPTVRKTRQDGSQEAPEAPLSSELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPS 1130

Query: 420  TIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETS 479
            T  A+P     TS   +  T R S     V+ P              E   P A + + S
Sbjct: 1131 TSTAQPVTPKPTSQATRSRTNRSS-----VKTP--------------EPVVPTAPELQPS 1171

Query: 480  FQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHL 539
              + +P+ +E   PT Q       +++ +   ++       Q    P+    +P      
Sbjct: 1172 TSTDQPVTSE---PTSQVTRGRKSRSSVKTPETVVPTALELQ----PSTSTDRPVTSEPT 1224

Query: 540  TQATVQPLDLGFTITPES--KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQ 597
            +QAT    +     TPE    T  EL P+   T T  P    P  +  +G  N +    +
Sbjct: 1225 SQATRGRKNRSSVKTPEPVVPTAPELQPS---TSTDQPVTSEPTYQATRGRKNRS--SVK 1279

Query: 598  AQHPVSPSVTV--QLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
               PV P+             +TP+PT+    +T  +  + S K PE  +P   ++Q   
Sbjct: 1280 TPEPVVPTAPELRPSTSTDRPVTPKPTSR---TTRSRTNMSSVKTPETVVPTAPELQIST 1336

Query: 656  SH--------LTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQ 707
            S          +R T    ++     P+S   + P     T+   P  PE T   +   +
Sbjct: 1337 STDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTPEPTSRATRGRK 1396

Query: 708  AQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET-------STQPPDLGLAIIPEPT 760
             + S  T  T+ P   +L  +T     V P PT++ T       S + P+  +   P   
Sbjct: 1397 NRSSGKTPETLVPTAPKLEPSTSTDQPVTPEPTSQATRGRTNRSSVKTPETVVPTAP--- 1453

Query: 761  TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPE 820
             E   ST+ ++   P P    T  R+       P  + P    L Q+ + T     + P 
Sbjct: 1454 -ELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAPEL-QASASTDQPVTSEPT 1511

Query: 821  EHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNT 862
                    N   + T    + +  +L P     Q   PEP +
Sbjct: 1512 SRTTRGRKNRSSVKTPETVVPAAPELQPSTSTDQPVTPEPTS 1553



 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 183/842 (21%), Positives = 293/842 (34%), Gaps = 127/842 (15%)

Query: 46   PLQLTSNPLGPPEPWSSHSS-HFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTE 104
            P  +   P  P +P +S S  H       +P LP+            S E P  P  S  
Sbjct: 1039 PPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPLLPSIKPTVRKTRQDGSQEAPEAPLSS-- 1096

Query: 105  NLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEII 164
             L PF                F A+    +   S     PV+PK   +    R + + + 
Sbjct: 1097 ELEPFHPKPKIRTRKSSRMTPFPATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSV- 1155

Query: 165  GIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRV----KSDEPPGPSEQVGPSQFHL 220
                   TP+    T      ST T  P +  P  +V    KS       E V P+   L
Sbjct: 1156 ------KTPEPVVPTAPELQPSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALEL 1209

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEV 280
            +P T    T   + S    Q    +  +   + P  +   AP L P +S +         
Sbjct: 1210 QPSTS---TDRPVTSEPTSQATRGRKNRSSVKTPEPVVPTAPELQPSTSTDQPVTSEPTY 1266

Query: 281  SVQPPGEDQAYYHLPNITVKPA-------DVEVTITSEPTNETESSQAQQETPIQFPEEV 333
                  ++++    P   V  A         +  +T +PT+ T  S+    + ++ PE V
Sbjct: 1267 QATRGRKNRSSVKTPEPVVPTAPELRPSTSTDRPVTPKPTSRTTRSRTNMSS-VKTPETV 1325

Query: 334  EPSA------TQQEAPIEPP--------------VPPMEHELSISEQQQPVQPSESPREV 373
             P+A      T  + P+ P               V   E  + I+ +  P   +E P  V
Sbjct: 1326 VPTAPELQISTSTDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQP--V 1383

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
               PT + T G+  ++     +P     T     PS S   P     +  EP+++     
Sbjct: 1384 TPEPTSRATRGR--KNRSSGKTPETLVPTAPKLEPSTSTDQP-----VTPEPTSQ----- 1431

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEE--AGPLAVQQET-------SFQSPE 484
                AT   +   +   P  +    P L P +S +    P    Q T       S ++PE
Sbjct: 1432 ----ATRGRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPE 1487

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             +    P   Q  A+ + P T+E   S  T       + + P  VV   PE    T +T 
Sbjct: 1488 TVVPTAPE-LQASASTDQPVTSEP-TSRTTRGRKNRSSVKTPETVVPAAPELQPST-STD 1544

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP 604
            QP      +TPE  +      T + +  + P+ +VP     Q    P+  ++Q   P   
Sbjct: 1545 QP------VTPEPTSRATRGRTNRSS-VKTPESIVPIAPELQ----PSTSRNQLVTPEPT 1593

Query: 605  SVTVQLLDLGLTI-TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATV 663
            S   +      ++ TPEP         P  +   P  P++T     +   + S  T   V
Sbjct: 1594 SRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSSVKTPKPV 1653

Query: 664  QPL--DLG-FT-----ITPKSMTEVEPSTALMTTA----PPPGHPEVTLPPSDKGQAQHS 711
            +P   DL  FT     +TP+++ +   S  L ++     P P  PE   P +        
Sbjct: 1654 EPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEFQSPVTTDQPISPE 1713

Query: 712  HLTQ--------ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDL-----GLAIIPE 758
             +TQ        A   P  L   I  KP +     P ++ +  Q          L  IPE
Sbjct: 1714 PITQPSCIKRQRAAGNPGSLAAPIDHKPCS-APLEPKSQASRNQRWGAVRAAESLTAIPE 1772

Query: 759  PTT----ETG-HSTALEK---------TTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSL 804
            P +    ET  H++ ++K         T   +P   Q+  RSL  +  PP + +P +  +
Sbjct: 1773 PASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMDSPPHQKQPQRGEV 1832

Query: 805  VQ 806
             Q
Sbjct: 1833 SQ 1834



 Score = 31.2 bits (69), Expect = 8.6
 Identities = 65/349 (18%), Positives = 126/349 (36%), Gaps = 44/349 (12%)

Query: 77   LPADPWDFDHLGPSASSEMPAPPQ------------------ESTENLVPFLDTWDSAGE 118
            +PA P     L PS S++ P  P+                  ES   + P L    S  +
Sbjct: 1531 VPAAP----ELQPSTSTDQPVTPEPTSRATRGRTNRSSVKTPESIVPIAPELQPSTSRNQ 1586

Query: 119  L--PLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQ 176
            L  P    +    + +     +P+  +P +P+        +    ++     +  T +S 
Sbjct: 1587 LVTPEPTSRATRCRTNRSSVKTPEPVVPTAPEPHPTTSTDQPVTPKLTSRATRRKTNRSS 1646

Query: 177  KQTLQN-EYSSTD----TPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
             +T +  E +++D    TP   S+ PE   +     G S+ +  S     P    PE   
Sbjct: 1647 VKTPKPVEPAASDLEPFTPTDQSVTPEAIAQG----GQSKTLRSSTVRAMPVPTTPEFQS 1702

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTL-PNHEVSV-QPPGEDQ 289
             + +       P   P  ++ + ++    + A P +    S  L P  + S  Q  G  +
Sbjct: 1703 PVTTDQPISPEPITQPSCIKRQRAAGNPGSLAAPIDHKPCSAPLEPKSQASRNQRWGAVR 1762

Query: 290  AYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVP 349
            A     ++T  P      +   P + ++  + +     +F  E++P A+Q        + 
Sbjct: 1763 A---AESLTAIPEPASPQLLETPIHASQIQKVEPAGRSRFTPELQPKASQSRKRSLATMD 1819

Query: 350  PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPG 398
               H      Q+QP +   S + V     +++T  +P +  +V    PG
Sbjct: 1820 SPPH------QKQPQRGEVSQKTVIIKEEEEDTAEKPGKEEDVVTPKPG 1862


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score = 80.1 bits (196), Expect = 2e-14
 Identities = 139/675 (20%), Positives = 242/675 (35%), Gaps = 122/675 (18%)

Query: 132   DLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPY 191
             ++ +K+ P ++ P      K+ PA+   + + I +  ++  P+  +           T  
Sbjct: 10444 EISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVP--------PTKV 10495

Query: 192   PGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLE 251
             P  LPP+  V   + P P  +        +PE   P+  E  +    +++ P   P+  E
Sbjct: 10496 PEVLPPKEVVPEKKVPVPPAK--------KPEAPPPKVPEAPKEVVPEKKVPVPPPKKPE 10547

Query: 252   EEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADV--EVTIT 309
               P+ + +   A  PE  +     P  E    PP         P +   P +V  E  + 
Sbjct: 10548 VPPTKVPEVPKAAVPEKKVPEAIPPKPE---SPP---------PEVPEAPKEVVPEKKVP 10595

Query: 310   SEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP----VPPME----HELSISEQQ 361
             + P  + E       TP++ PE  +    +++ P+ PP    VPP +     ++++ E++
Sbjct: 10596 AAPPKKPEV------TPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKK 10649

Query: 362   Q----PVQPSESPREVESSPTQ---QETPGQPPEHHEVTVSP----PGHHQTHHLASPSV 410
                  P +P   P EV   P +   +E P +  E  E    P    P         +P+V
Sbjct: 10650 VPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAV 10709

Query: 411   SVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPE------ 464
               K P++      E   EV    V ++    +     +  P  +      ++PE      
Sbjct: 10710 VAKKPELPPVKVPEVPKEV----VPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVP 10765

Query: 465   SSEEAGPLAVQQETSFQSPEPINNENPS-PTQQEAAAEHPQTAEEGESSLTHQE------ 517
                E  P  V +       +P+  E P+ P  + A +  P+  EE E     +E      
Sbjct: 10766 KKPEVPPAKVPEVPK----KPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEE 10821

Query: 518   -----APAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
                  A  + PE P   V + P+                 I PE K      P +K+   
Sbjct: 10822 KPVPVAEEEEPEVPPPAVPEEPK----------------KIIPEKKV-----PVIKKPEA 10860

Query: 573   QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPK 632
              PPK+  P+  + +    P P       P  P   V+     L   P+         P K
Sbjct: 10861 PPPKEPEPEKVIEKPKLKPRP---PPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 633   RTIVSPKHP----EVTLPHPDQVQTQHSHLTRATV---QPLDLGFTITPKSMTEVEPSTA 685
               +   K P    +V    P++       +   +V   +P +    + PK + +V+   A
Sbjct: 10918 VELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVK-KPA 10976

Query: 686   LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
             +    PP    EV +P   K + +    T+       + L     P  E KP P  E  +
Sbjct: 10977 VPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL-----PAPEPKPKPEAEVKT 11031

Query: 746   TQPPDLGLAIIPEPT 760
              +PP     + PEPT
Sbjct: 11032 IKPP----PVEPEPT 11042



 Score = 64.7 bits (156), Expect = 7e-10
 Identities = 161/792 (20%), Positives = 274/792 (34%), Gaps = 99/792 (12%)

Query: 122   EPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQ 181
             E E+F+  ++ L + + P+  +P    ++KK   ++      + I ++   P ++   + 
Sbjct: 10163 EEEEFVPEEEVLPE-VKPKVPVPAPVPEIKKKVTEKK-----VVIPKKEEAPPAKVPEVP 10216

Query: 182   NEYSSTDTPYPGS---LPPELRVKSDEPPGPSEQVG--PSQFHLEPETQNPETLEDIQSS 236
              +        P     LP E+  + +E P   E++   P       E   P   E I+ +
Sbjct: 10217 KKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVEEVAPPRVPEVIKKA 10276

Query: 237   SLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPN 296
                 EAP  +P+ +E  P+ + ++ P       ++    P  +V   P    +    +P 
Sbjct: 10277 V--PEAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAPPAKVPEVPKKVPEKKVLVPK 10334

Query: 297   ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEAPIEPPVPPME--- 352
                 P     T+  E      S   +QE  ++   E+E   A  +E P E     +E   
Sbjct: 10335 KEAVPPAKGRTVLEEKV----SVAFRQEVVVKERLELEVVEAEVEEIPEEEEFHEVEEYF 10390

Query: 353   -----HELS--ISEQQQPVQPSESPREV-------ESSPTQQ-ETPGQPPEHHEVT--VS 395
                  HE+   I  +Q  V+      +V       E+   +  E P  PP+  E++  + 
Sbjct: 10391 EEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIEVFEAEEVEVFEKPKAPPKGPEISEKII 10450

Query: 396   PPGHHQTHHLASPSVSVKPPDVQLTIAAE-----------PSAEVGTSLVHQEATTRLSG 444
             PP    T  +       K P+V   I  E           P  +V   L  +E       
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKV 10510

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA-AEHP 503
                 V P       PP +PE+ +E  P     E     P P   E P     E   A  P
Sbjct: 10511 P---VPPAKKPEAPPPKVPEAPKEVVP-----EKKVPVPPPKKPEVPPTKVPEVPKAAVP 10562

Query: 504   QTAEEGESSLTHQEAPAQTPEFPNVVV------AQPPEHSHLTQATVQPLDLGFTITPES 557
             +           +  P + PE P  VV      A PP+   +T   V   +    + PE 
Sbjct: 10563 EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVP--EAPKEVVPEK 10620

Query: 558   KTEVELSPTMKETPT---QPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPS-VTVQLLDL 613
             K  V      +  PT   + PK  VP+ +V + +  P P     +    P  V ++    
Sbjct: 10621 KVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIP-PKPESPPPEVFEEPEEVALEEPPA 10679

Query: 614   GLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTI- 672
              +   PEP      + PPK+ +   K P V    P+    +   + +  V    +   + 
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739

Query: 673   ---------TPKSMTEVEPSTALMTT----APPPGHPEVTLPPSDKGQAQHSHLTQATVQ 719
                       P+   EV P   +        PP   PEV   P  + +       +A   
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESP 10799

Query: 720   PLDL-ELTITTKPTTEV-----KPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTT 773
             P ++ E      P  E+     KP P  EE   + P   +   P+          ++K  
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPE 10859

Query: 774   AP---RPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKAL---TAPEEHKASTS 827
             AP    P+  + + +   +   PP    P ++ +   E   Q KA+     PE+ +    
Sbjct: 10860 APPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDV--KEKIFQLKAIPKKKVPEKPQVPEK 10917

Query: 828   TNICELCTCGDE 839
               +  L   G E
Sbjct: 10918 VELTPLKVPGGE 10929



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 143/715 (20%), Positives = 250/715 (34%), Gaps = 78/715 (10%)

Query: 123   PEQFLASQQDLKDKLSPQERLPVSPKKL---KKDPAQRWSLAEIIGI-IRQLSTPQSQKQ 178
             PE+ + +    K+K+ P  ++P  PKK    KK P +   + E +   + +     +Q++
Sbjct: 9589  PEKKVPAPVPKKEKVPPP-KVPEEPKKPVPEKKVPPKVIKMEEPLPAKVTERHMQITQEE 9647

Query: 179   TLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSL 238
              +    +  + P    +P E   K   P     ++ P +    P          ++   +
Sbjct: 9648  KVLVAVTKKEAPPKARVPEE--PKRAVPEEKVLKLKPKREEEPPAKVTEFRKRVVKEEKV 9705

Query: 239   QQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNIT 298
               EAP + PQ ++E     ++E           + TL    VSVQ   E + Y       
Sbjct: 9706  SIEAPKREPQPIKEVTIMEEKE----------RAYTLEEEAVSVQREEEYEEY------- 9748

Query: 299   VKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS 358
              +  D +     EPT E +  +  +E   +  EE E   T+ E PI  PV P      + 
Sbjct: 9749  -EEYDYKEFEEYEPTEEYDQYEEYEEREYERYEEHEEYITEPEKPI--PVKP------VP 9799

Query: 359   EQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQ 418
             E+  P +P   P +V      +E    P         P    +   +    + +     +
Sbjct: 9800  EEPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPKKVFEEKIRISITKRE 9859

Query: 419   LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA-IQHGGPPLLPE--SSEEAGPLAVQ 475
                  EP+A+V        A  ++     +V PP  +      L PE  + EE     V+
Sbjct: 9860  KEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELEPEEVAFEEEVVTHVE 9919

Query: 476   QETSFQSPEPINNENPSPTQQEAAAEHP-QTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
             +    +  E I+ E    T++E     P +  E     +  ++ P   P+      A+ P
Sbjct: 9920  EYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVP 9979

Query: 535   EHSHLTQATVQPL-------------DLGFTITPESKTEVELSPTMKETPT---QPPKKV 578
             E     +  V  L             ++     PE K  V +   ++  P    + PKK 
Sbjct: 9980  EVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPEVPKKP 10039

Query: 579   VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP-TTEVGHSTPPKRTIVS 637
             VP+ +    V  P P + +A     P V  +L+      TP P   E      PK+    
Sbjct: 10040 VPEKK----VPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPPKVPKKR--E 10093

Query: 638   PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPE 697
             P    V LP  ++V  +   +    V P +       + +   E          PP   E
Sbjct: 10094 PVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEE 10153

Query: 698   VTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEET----STQPPDLGL 753
             V  P  +    +   + +  V P          P  E+K   T ++       + P   +
Sbjct: 10154 VP-PEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIPKKEEAPPAKV 10212

Query: 754   AIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSE 808
               +P+   E       ++   P+ + V  +     EVT  P E EP  +  +  E
Sbjct: 10213 PEVPKKVEE-------KRIILPKEEEVLPV-----EVTEEPEE-EPISEEEIPEE 10254



 Score = 58.9 bits (141), Expect = 4e-08
 Identities = 113/524 (21%), Positives = 192/524 (36%), Gaps = 86/524 (16%)

Query: 90    SASSEMPAPPQEST-ENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPK 148
             S   E+P  P+E   E  VP           P +PE       +   ++ P++++PV P 
Sbjct: 10576 SPPPEVPEAPKEVVPEKKVPAAP--------PKKPEVTPVKVPEAPKEVVPEKKVPVPPP 10627

Query: 149   KLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPEL-----RVKS 203
             K  + P  +      +  + +++ P       + +      P P S PPE+      V  
Sbjct: 10628 KKPEVPPTK------VPEVPKVAVP-------EKKVPEAIPPKPESPPPEVFEEPEEVAL 10674

Query: 204   DEPPG----PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEE------- 252
             +EPP       E   P Q  + P+   PE       +   +  P ++P++ +E       
Sbjct: 10675 EEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKV 10734

Query: 253   ------EPSSMQQEAPALPPESSMESLTLPNHEVSVQ-----PPGEDQAYYHLPNITVKP 301
                   +P +   + P +P E       +P  +V+V      PP +       P +  KP
Sbjct: 10735 PLVVPKKPEAPPAKVPEVPKE------VVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKP 10788

Query: 302   A-DVEVTITSEPTNETESSQ--AQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS 358
             A  V     S P    E  +  A +E      E+  P A ++E  + PP  P E +  I 
Sbjct: 10789 AVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIP 10848

Query: 359   EQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQ 418
             E++ PV      ++ E+ P ++  P +  E  ++   PP        A P   VK    Q
Sbjct: 10849 EKKVPV-----IKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPP----APPKEDVKEKIFQ 10899

Query: 419   LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
             L    +        +  +   T L   G + +   ++   P   PE  EE    +V ++ 
Sbjct: 10900 LKAIPKKKVPEKPQVPEKVELTPLKVPGGEKK---VRKLLPERKPEPKEEVVLKSVLRKR 10956

Query: 479   SFQSPEPINNENPSPTQQEAAAE--HPQTAEEGE-SSLTHQE----APAQTPEFPNVVVA 531
               +    +  +     ++ A  E   P+  EE E  ++T +E     P + PE    +  
Sbjct: 10957 PEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPL 11016

Query: 532   QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
               PE     +A V+      TI P     VE  PT    P   P
Sbjct: 11017 PAPEPKPKPEAEVK------TIKP---PPVEPEPTPIAAPVTVP 11051



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 106/504 (21%), Positives = 191/504 (37%), Gaps = 71/504 (14%)

Query: 114   DSAGELPLEPEQFLASQQDL--KDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLS 171
             + A ++P++P++ +A ++    + +++P  R+P  PK+L  +P +     E++  + +  
Sbjct: 9865  EPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKEL--EPEEVAFEEEVVTHVEEYL 9922

Query: 172   TPQSQKQTLQNEYSSTDTPYPGSLP------PELRVKSDEPPGPSEQVGPSQFHLEPET- 224
               + ++   + E   T+      +P      P   V  ++ P P  +   +     PE  
Sbjct: 9923  VEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVP 9982

Query: 225   QNPETLEDIQSSSLQQEAPAQLPQL----LEEE----PSSMQQEAP-ALPPESSMESLTL 275
             + PE    +     ++  PA++P++    + EE    P   + EAP A  PE  +    +
Sbjct: 9983  KKPEEKVPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVPVPKKVEAPPAKVPE--VPKKPV 10040

Query: 276   PNHEVSVQPPGEDQA----YYHLPNITV----KPADVEVTITSEPTNETESSQAQQETPI 327
             P  +V V  P + +A       +P   +    KP  V   + + P  +    +     P+
Sbjct: 10041 PEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKKVEAPPP-KVPKKREPVPVPV 10099

Query: 328   QFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQP- 386
               P+E E    ++  P E  +P  E  L   E+  P +    P E E  P ++E P +  
Sbjct: 10100 ALPQEEEVLFEEEIVPEEEVLPEEEEVLPEEEEVLPEEEEVLPEEEEIPPEEEEVPPEEE 10159

Query: 387   --PEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSG 444
               PE  E                P   V P          P  E+   +  ++       
Sbjct: 10160 YVPEEEEFV--------------PEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVI---- 10201

Query: 445   SGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQ 504
                +  PPA      P +P+  EE   + + +E      E        P  +E   E P 
Sbjct: 10202 PKKEEAPPA----KVPEVPKKVEEK-RIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPP 10256

Query: 505   TAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELS 564
             + EE E     + AP + PE     V + P  + + +    P        PE K  V + 
Sbjct: 10257 SIEEVE-----EVAPPRVPEVIKKAVPEAP--TPVPKKVEAPPAKVSKKIPEEKVPVPVQ 10309

Query: 565   PTMKETP----TQPPKKVVPQLRV 584
                KE P     + PKK VP+ +V
Sbjct: 10310 --KKEAPPAKVPEVPKK-VPEKKV 10330



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 104/539 (19%), Positives = 196/539 (36%), Gaps = 93/539 (17%)

Query: 176  QKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQS 235
            +++ +Q +    +  +   +P ++  K   PP P     P    +E  ++  E  E +Q 
Sbjct: 9146 EREVIQVQKEVYEESHERKVPAKVPEKKAPPP-PKVIKKPVIEKIEKTSRRMEE-EKVQV 9203

Query: 236  SSLQQEAPAQLPQLLEEEPSS---MQQEAPALPPES---SMESLTLPNH---EVSVQPPG 286
            + + + +   +PQ     P     ++ + PA+  +    S E +   +H   EVSV  P 
Sbjct: 9204 TKVPEVSKKIVPQKPSRTPVQEEVIEVKVPAVHTKKMVISEEKMFFASHTEEEVSVTVPE 9263

Query: 287  EDQAYYHLPNITVKPADVEVTITSEPTNET----ESSQAQQETPIQFPEEVEPSATQQEA 342
              +       +T +   V ++   EP  +     E    ++  P+  P++VEP A +   
Sbjct: 9264 VQKEI-----VTEEKIHVAISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPE 9318

Query: 343  PIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQE------------TPGQPPE-- 388
              + PVP  +  + +  +++P  P + P EV   P  +E             P + PE  
Sbjct: 9319 VPKKPVPEEKKPVPV-PKKEPAAPPKVP-EVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQ 9376

Query: 389  -----HHEVTV-------SPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSA-EVGTSLVH 435
                   ++T+        PP   +      P      P  +  +   P    +    V 
Sbjct: 9377 KGVVTEEKITIVTQREESPPPAVPEIPKKKVPEERKPVPRKEEEVPPPPKVPALPKKPVP 9436

Query: 436  QEATTRLSGSGNDVEPPAIQHGGPPLLPES---SEEAGPLAVQQETSFQSPEPINNENPS 492
            +E             PP  +     ++ E    +EE    AV Q       E    E  S
Sbjct: 9437 EEKVAVPVPVAKKAPPPRAEVSKKTVVEEKRFVAEEKLSFAVPQRVEVTRHEVSAEEEWS 9496

Query: 493  PTQQE-----AAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPL 547
             +++E     +     +  EE E+ +T  E   +  E+    V +   H    +   +P 
Sbjct: 9497 YSEEEEGVSISVYREEEREEEEEAEVTEYEVMEEPEEY----VVEEKLHIISKRVEAEPA 9552

Query: 548  DL------GFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP 601
            ++         + P+   ++E  P  K    + PKK+VP+ +    V  P P +++   P
Sbjct: 9553 EVTERQEKKIVLKPKIPAKIEEPPPAK--VPEAPKKIVPEKK----VPAPVPKKEKVPPP 9606

Query: 602  VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
              P               EP   V    P K+  V PK  ++  P P +V  +H  +T+
Sbjct: 9607 KVPE--------------EPKKPV----PEKK--VPPKVIKMEEPLPAKVTERHMQITQ 9645



 Score = 41.6 bits (96), Expect = 0.006
 Identities = 77/377 (20%), Positives = 134/377 (35%), Gaps = 61/377 (16%)

Query: 44    KDPLQLTSNPLGPPEPWSSHSSHF-PRESPHAPTLPADPWDFDHLGPSASSEMPAPPQES 102
             K PL +   P  PP           P +    P  P  P       P+   E+P  P   
Sbjct: 10733 KVPLVVPKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVP-------PAKVPEVPKKPVLE 10785

Query: 103   TENLVPFLDTWDSAG----ELPLE--PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQ 156
              +  VP  +  +S      E P E  PE+ +A +++    ++ +E   V P  + ++P +
Sbjct: 10786 EKPAVPVPERAESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKK 10845

Query: 157   RWSLAEIIGIIRQLSTPQSQ---KQTLQNEYSSTDTPYPGSLPPELRVKS---------- 203
                  ++  I +  + P  +   ++ ++        P P   PP+  VK           
Sbjct: 10846 IIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPK 10905

Query: 204   ----DEP-------------PGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQL 246
                 ++P             PG  ++V       +PE +    L+ +     ++E P   
Sbjct: 10906 KKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVE 10965

Query: 247   PQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEV 306
             P+ LE+       E P   P   +E  T+   E  +  P +      +P I  KPA    
Sbjct: 10966 PKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTK------VPEI--KPAIPLP 11017

Query: 307   TITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQ--QPV 364
                 +P  E E    +       P  VEP  T   AP+  PV   + E    +++  +P 
Sbjct: 11018 APEPKPKPEAEVKTIK-------PPPVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPK 11070

Query: 365   QPSESPREVESSPTQQE 381
              P +   +   SP + E
Sbjct: 11071 GPIKGVPKKTPSPIEAE 11087


>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
          Length = 1573

 Score = 79.3 bits (194), Expect = 3e-14
 Identities = 125/521 (23%), Positives = 172/521 (33%), Gaps = 77/521 (14%)

Query: 382  TPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
            +PG PP           H  T     P    +PP    T  A P+   G S         
Sbjct: 969  SPGSPPTLRV-------HGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPS--------- 1012

Query: 442  LSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP--TQQEAA 499
               S     P         L P S+  +   +   +TS  +P+P +  NP    T  + A
Sbjct: 1013 --ASPGPPGPALTSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFA 1070

Query: 500  AEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLT-------QATVQPLDLGFT 552
               P ++     +LT + +P   P  P  + + P   S +T       Q           
Sbjct: 1071 LSTPDSSVV--PALTPEPSPTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLD 1128

Query: 553  ITPESKTEVELS----------PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPV 602
             TP S T  E S          PT    PT  P  +             TP      HP 
Sbjct: 1129 TTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPT 1188

Query: 603  SPSVTVQLLDLGLTITPEPTTEVGHST---------PPKRTIVSPKHPEVTLPHPDQVQT 653
            + + +  + D   T TP+P T + HST          P  T+     P  T PHP    T
Sbjct: 1189 TITHSTMIPDP--TTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHP----T 1242

Query: 654  QHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHL 713
               H T  T   +    T TP+  T ++P+T    T  P  HP  T  P+        H 
Sbjct: 1243 TTPHPTTITHSTMIPDPTTTPQPFTTMQPTTMPHPTTTP--HPTTTPHPTTT-----PHP 1295

Query: 714  TQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTT 773
            T      +  + T T  PTT   P PTT    T P      +I   +  T   T L   T
Sbjct: 1296 TTTPHPTMTPDPTTTPYPTTT--PDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPT 1353

Query: 774  APRPDRVQTLHRSLTEVTG---------PPTELEPAQDSLVQSESYTQNKALTAPEEHK- 823
               P    +LH  LT             P  E  PA +S     S   +    + E+ K 
Sbjct: 1354 L-APTVKPSLHPQLTFTAPAPHTSTSQIPTLEPSPALESSPSRSSTATSMDPLSTEDFKP 1412

Query: 824  -ASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTH 863
              S S N+    T      S + ++P+  L   P   P  H
Sbjct: 1413 PRSQSPNLTPPPTHTPHSASDLTVSPDPLLS--PTAHPLDH 1451



 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 131/576 (22%), Positives = 194/576 (33%), Gaps = 98/576 (17%)

Query: 165  GIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPET 224
            G  R   +P + +  +  +  S   P+P   PP        PP PS     S     P  
Sbjct: 965  GTTRSPGSPPTLR--VHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPAL 1022

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP 284
             +  + E    S+L  EA +  P      P    +  P L   S   +L+ P+  V    
Sbjct: 1023 TSDSSRELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSV---- 1078

Query: 285  PGEDQAYYHLPNITVKPADVEV-TITSEPTNETESSQAQQETPIQFPEEVEP-SATQQEA 342
                     +P +T +P+   + T+  E T++  +           P EV   S T ++ 
Sbjct: 1079 ---------VPALTPEPSPTPLPTLPKELTSDPST-----------PSEVTSLSPTSEQV 1118

Query: 343  PIEPPVPPME---HELSISEQQQPVQPSESPREVES-SPTQQE----------TPGQPPE 388
            P     P ++   +  ++SE  +   PS SP    +  PT             TP  P  
Sbjct: 1119 PESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMAPDPITTLNPTVTPHFPTT 1178

Query: 389  HHEVTVSPPGHHQTHHLASPSVSVKPPD----VQLTIAAEPSAEVGTSLVHQEATTRLSG 444
             H  T +P     TH    P  +  P         T+  +P+         Q  TT  S 
Sbjct: 1179 PHP-TTTPHPTTITHSTMIPDPTTTPQPFTTITHSTMIPDPTTTPQPFTTMQPTTTPHST 1237

Query: 445  SGNDV---EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAE 501
            + +      P  I H    ++P+ +    P    Q T+   P P    +P+ T       
Sbjct: 1238 TPHPTTTPHPTTITHS--TMIPDPTTTPQPFTTMQPTTM--PHPTTTPHPTTTPHPTTTP 1293

Query: 502  HPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEV 561
            HP T        T    P  TP +P      P    H T        +  T++  +    
Sbjct: 1294 HPTTTPHP----TMTPDPTTTP-YP-TTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGT 1347

Query: 562  ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEP 621
            ELS     +PT  P  V P L      T P P    +Q P              T+ P P
Sbjct: 1348 ELS-----SPTLAP-TVKPSLHPQLTFTAPAPHTSTSQIP--------------TLEPSP 1387

Query: 622  TTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE-- 679
              E   S     T + P   E   P     ++Q  +LT           T TP S ++  
Sbjct: 1388 ALESSPSRSSTATSMDPLSTEDFKP----PRSQSPNLTPPP--------THTPHSASDLT 1435

Query: 680  VEPSTALMTTAPPPGHP---EVTLPPSDKGQAQHSH 712
            V P   L  TA P  HP    +TL P+  GQ+   H
Sbjct: 1436 VSPDPLLSPTAHPLDHPPLDPLTLGPT-PGQSPGPH 1470



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 123/602 (20%), Positives = 182/602 (30%), Gaps = 124/602 (20%)

Query: 56   PPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPP--QESTENLVPFLD-- 111
            P +PW       P  +  AP  P+        GPSAS   P P    +S+  L P     
Sbjct: 985  PRKPWPERRPPRPAATRTAPPTPSP-------GPSASPGPPGPALTSDSSRELTPHSALT 1037

Query: 112  ---TWDSAGELPLEPEQFLASQQDL----------------KDKLSPQER---LPVSPKK 149
               T D+    P  P+    +  DL                   L+P+     LP  PK+
Sbjct: 1038 SEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKE 1097

Query: 150  LKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGP 209
            L  DP+    +  +     Q+    +        YSST + Y  S  P         P P
Sbjct: 1098 LTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDP------SPSPHP 1151

Query: 210  SEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESS 269
            +    P+       T NP       ++      P          P+++        P ++
Sbjct: 1152 TTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTP---------HPTTITHSTMIPDPTTT 1202

Query: 270  MESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF 329
             +  T   H   +  P         P  T++P     + T  PT     +     T I  
Sbjct: 1203 PQPFTTITHSTMIPDPTTTPQ----PFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPD 1258

Query: 330  PEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEH 389
            P       T  +    P      H  +         P+ +P      PT    P   P  
Sbjct: 1259 PTTTPQPFTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPH-----PTMTPDPTTTP-- 1311

Query: 390  HEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV 449
                 + P    T H  +P  S  P    +T  + P++ +GT L                
Sbjct: 1312 --YPTTTPDPTTTPHPTTPDPSSTP---VITTVSLPTS-LGTEL---------------- 1349

Query: 450  EPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEG 509
                     P L P       P     + +F +P P  + +  PT + + A     +   
Sbjct: 1350 -------SSPTLAPTVKPSLHP-----QLTFTAPAPHTSTSQIPTLEPSPA---LESSPS 1394

Query: 510  ESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKE 569
             SS      P  T +F        P  S     T  P     T TP S +++ +SP    
Sbjct: 1395 RSSTATSMDPLSTEDF-------KPPRSQSPNLTPPP-----THTPHSASDLTVSPDPLL 1442

Query: 570  TPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
            +PT  P    P   +  G   PTPGQ    H             G  + P P   V    
Sbjct: 1443 SPTAHPLDHPPLDPLTLG---PTPGQSPGPH-------------GPCVAPTPPVRVMACE 1486

Query: 630  PP 631
            PP
Sbjct: 1487 PP 1488



 Score = 31.6 bits (70), Expect = 6.6
 Identities = 39/139 (28%), Positives = 51/139 (36%), Gaps = 36/139 (25%)

Query: 674 PKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTT 733
           PKS  +     A   T  PP      +P +   +AQ          P DL    T   TT
Sbjct: 625 PKSTKKWVTKNAKRPTTQPP-----VMPTTKHSRAQ---------SPPDLTSQTTAALTT 670

Query: 734 EVKPSPTTEETSTQPPDLGLAIIPEPTTE-----TGHSTALEKTTAPRPDRVQTLHRSLT 788
           E    PT+E T              PTTE     T H+TA     APR    +T+    T
Sbjct: 671 EASRRPTSEFTR------------RPTTEAPQRWTSHTTATLTPQAPRERTTKTMAMLTT 718

Query: 789 EVTGPPTELEPAQDSLVQS 807
           +  GP    E   +S ++S
Sbjct: 719 Q--GPQ---EMTSESTIKS 732


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 79.0 bits (193), Expect = 4e-14
 Identities = 176/769 (22%), Positives = 242/769 (31%), Gaps = 155/769 (20%)

Query: 49  LTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVP 108
           L+S+PL  P P  + +   P     A  LPA       L PS     P P    + +  P
Sbjct: 299 LSSSPLATPSPSGTKARPVPPPDNAATPLPAT------LPPSPPLATPLPLAPPSPSAPP 352

Query: 109 FLDTWDSAGELP---------LEPEQFLASQQDLK------DKLSPQERLPVSPKKLKKD 153
            L T  S    P           P Q   S Q +          SP  + P SP  L   
Sbjct: 353 SLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSL 412

Query: 154 PAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE---LRVKSDEPPGPS 210
            A     +  +       T  S +QT   + S T    P S PP+   L+     P  P 
Sbjct: 413 QATTSLGSPTLQATHSFLT-MSPRQT---QASLTSPSRPASTPPDSPPLQAPLSLPASP- 467

Query: 211 EQVGPSQFHLEPETQ---NPETLEDIQS-SSLQQEAP-AQLPQLLEEEPSSMQQEAPALP 265
               P Q  L P      +P T+  +Q+ SSL   +P A L  L+           P L 
Sbjct: 468 ----PLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLSSLI----------MPPLE 513

Query: 266 PESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQ--- 322
            +SS+   +L     S+  P  +    +LP++   P        + P  ET    A    
Sbjct: 514 TQSSLAPPSLQTPPASLTTPPLE----NLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL 569

Query: 323 --QETPIQFPEEVEPSATQQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSP 377
               +P+  P    PS+     P  PP    PP++   S         P ++P  +   P
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 378 TQQ--ETPGQPPEHHEVTVSP--PGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
            Q     P  PP     T SP  P     H L +P      P VQ   +   S  V  S 
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS- 688

Query: 434 VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
               AT       +   PP      PP  P  S  A P         Q+P P+       
Sbjct: 689 ----ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP-------QAPPPL------- 730

Query: 494 TQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTI 553
                AA   Q      +S     +    P  P ++ A P +                 +
Sbjct: 731 -----AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQ-----------------V 768

Query: 554 TPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDL 613
            P     + +SP  K  P  PP    P L   Q + +P P     Q P SPS ++ +  L
Sbjct: 769 PPSPPASLPMSPLAKPPPQAPPALATPPL---QALPSP-PASFPGQAPFSPSASLPMSPL 824

Query: 614 GL------TITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLD 667
                    +   P  +V  S P   T+ +P+ P    P PD                  
Sbjct: 825 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT--PGPD------------------ 864

Query: 668 LGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSD-KGQAQHSHLTQATVQPLDLELT 726
                     T V      +  AP P  P    P S   G     H + AT  P +L   
Sbjct: 865 ----------TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELR-- 912

Query: 727 ITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
                       P     ++ PPD  LA         G +  L    AP
Sbjct: 913 -------GYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAP 954



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 143/588 (24%), Positives = 203/588 (34%), Gaps = 100/588 (17%)

Query: 36  EAQPLEWVKDPLQLTSNPLGPPEPWSSHS--SHFPRESPHAPTLPADPWDFDHLGPSASS 93
           +A P       LQ T++ LG P   ++HS  +  PR++  + T P+ P         AS+
Sbjct: 401 QAPPSPLALSSLQATTS-LGSPTLQATHSFLTMSPRQTQASLTSPSRP---------AST 450

Query: 94  EMPAPPQESTENLV--PFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLK 151
              +PP ++  +L   P L T  S    PL     +   Q L    S   + P+S   L 
Sbjct: 451 PPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPLS--SLI 508

Query: 152 KDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTP----YPGSLPPELRVKSDEPP 207
             P +  S          L+ P     +LQ   +S  TP     P   PP L+  S    
Sbjct: 509 MPPLETQS---------SLAPP-----SLQTPPASLTTPPLENLPSLAPPPLQTASAPLT 554

Query: 208 GPSEQVGPSQFHLE-PETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPP 266
            P         HLE P    P  L         Q  P+ L     E PSS+    P  PP
Sbjct: 555 TP---------HLETPPCPAPCPL---------QAPPSPLTTPPPETPSSIATPPPQAPP 596

Query: 267 ESSMESLT-LPNHEVS--VQPPGEDQAYYHLPNITVKPAD-VEVTITSEPTNETESSQAQ 322
             +   L  LP+  +S    PP +      LP +   P+      ++   T   ++  A 
Sbjct: 597 ALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNAL 656

Query: 323 QETPIQFPEEVEPSATQQ---EAPIEPPV-----PPMEHELSISE---QQQPVQPSESPR 371
               +Q P    PS   Q     P  PPV     PP +   S++    Q  P  P+  P 
Sbjct: 657 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 716

Query: 372 EVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVK----------PPDVQLTI 421
              ++P  Q  P       +V  SPP        A+P   V           PP    ++
Sbjct: 717 SPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASL 776

Query: 422 AAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQ 481
              P A+         AT  L    +   PPA   G  P  P +S    PLA       Q
Sbjct: 777 PMSPLAKPPPQAPPALATPPLQALPS---PPASFPGQAPFSPSASLPMSPLATPPP---Q 830

Query: 482 SP----EPINNENPSP-------TQQEAAAEHPQTAEEGESSLTHQEAPAQTP---EFPN 527
           +P     P+    PSP         +      P T+  G   LT   AP   P     P+
Sbjct: 831 APPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPGPPPPPSRSPS 889

Query: 528 VVVAQPPEHSHLTQATVQPLDL-GFTITPESKTEVELSPTMKETPTQP 574
             ++ P    H + AT  P +L G+   PE        P  +     P
Sbjct: 890 STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHP 937



 Score = 54.3 bits (129), Expect = 9e-07
 Identities = 148/696 (21%), Positives = 221/696 (31%), Gaps = 121/696 (17%)

Query: 138 SPQERLPVSPKKLKKDPAQ----RWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPG 193
           SP+   PV+P  L+   A     R  LAE  G I   + P+S  +      + T +  P 
Sbjct: 32  SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPA 91

Query: 194 SLPPELRVKSDEPP------GPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLP 247
           S PP        PP      GP    G +     P     + L      ++ +    + P
Sbjct: 92  SRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAP 151

Query: 248 QLLEEEPSSMQQEAPALP--PESSME----------SLTLPNHEVSVQPPGEDQAYYHLP 295
           +       + +  +   P  P  +M            L  P      +PP E       P
Sbjct: 152 KRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEG------P 205

Query: 296 NITVKPADVEVTITSEPT------------NETESSQAQQETPIQFPEEVEPSAT-QQEA 342
             +V  A    T    P                  S +   TP+  P    PSA     A
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 343 PIEPPVP-PMEHELSISEQQQPVQPSESPR--EVESSPTQQETPGQ------PPEHHEVT 393
           P  P  P P   +     Q  P +   +P    + SSP    +P        PP  +  T
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAAT 325

Query: 394 VSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPA 453
             P     +  LA+P + + PP         PSA      +     T  S +   +  P 
Sbjct: 326 PLPATLPPSPPLATP-LPLAPPS--------PSAPPSLQTLPSPPATPPSQAPPSMTTPP 376

Query: 454 IQHGGPPLLPESSEEAGPLAVQQETSFQSPEPI-------NNENPSPTQQEAAAEHPQTA 506
           +Q   PP L        P ++   +    P P+            SPT Q   +    + 
Sbjct: 377 MQ--APPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSP 434

Query: 507 EEGESSLTHQEAPAQTP------EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTE 560
            + ++SLT    PA TP      + P  + A PP  + L+ A V PL    TI P     
Sbjct: 435 RQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPA-VSPLSSPLTIHPLQA-- 491

Query: 561 VELSPTMKETPTQPPKKVV-PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP 619
             LS     +P  P   ++ P L     +  P+      Q P +   T  L +L  ++ P
Sbjct: 492 --LSSLASHSPQAPLSSLIMPPLETQSSLAPPS-----LQTPPASLTTPPLENLP-SLAP 543

Query: 620 EPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE 679
                     PP +T  +P    +T PH +               P        P  +T 
Sbjct: 544 ----------PPLQTASAP----LTTPHLETPPC-----------PAPCPLQAPPSPLTT 578

Query: 680 VEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP 739
             P T      PPP  P     P  +G         AT  P          P   + P  
Sbjct: 579 PPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPP-------QAPPXLALPPLQ 631

Query: 740 TTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAP 775
                   PP   L+ +  P+ +  ++ A+    AP
Sbjct: 632 APPSPPASPP---LSPLATPSPQAPNALAVHLLQAP 664



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 111/481 (23%), Positives = 161/481 (33%), Gaps = 84/481 (17%)

Query: 358 SEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDV 417
           S +    +P  S R   + P +  +PG         VS PG       AS +    P   
Sbjct: 86  SSRNPASRPPASGRGERAPPAKNTSPGP--------VSSPGR------ASGTTRPGPLGQ 131

Query: 418 Q-LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP-PLLPESSEEAGPLAVQ 475
           + L I+AE +   G +    + +   +G+  D   P    G P P +   S  AG     
Sbjct: 132 KGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT--PGTPSPAMARRSRAAG----- 184

Query: 476 QETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPE 535
             T    P P  +  P P  +         +   E S T     A+        + +P  
Sbjct: 185 --TEVGLPRPAPSARPRPPTE---GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239

Query: 536 HSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
            S  + AT  PL       P ++     +P     P+QP  K +  LR  Q VT P    
Sbjct: 240 RSLSSSAT--PLSSPARSGPSARG----TPRAPAHPSQPKPKGLQALRPPQ-VTPPRKDA 292

Query: 596 DQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQH 655
             A  P+S S            TP P+       PP     +P  P    P P       
Sbjct: 293 APALGPLSSSPLA---------TPSPSGTKARPVPPPDNAATPL-PATLPPSP------- 335

Query: 656 SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQ 715
                    PL     + P S +   PS  L T   PP  P    PPS       +  + 
Sbjct: 336 ---------PLATPLPLAPPSPS-APPS--LQTLPSPPATPPSQAPPSMTTPPMQAPPSL 383

Query: 716 ATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHS--------T 767
            T+ P+ +  ++T+ P+ +  PSP    +      LG      PT +  HS        T
Sbjct: 384 QTIPPIQVPHSLTS-PSLQAPPSPLALSSLQATTSLG-----SPTLQATHSFLTMSPRQT 437

Query: 768 ALEKTTAPRPDRV----QTLHRSLTEVTGPP--TELEPAQDSLVQSESYTQNKALTAPEE 821
               T+  RP         L   L+    PP  T L PA   L    +    +AL++   
Sbjct: 438 QASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLAS 497

Query: 822 H 822
           H
Sbjct: 498 H 498


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 77.4 bits (189), Expect = 1e-13
 Identities = 151/673 (22%), Positives = 231/673 (34%), Gaps = 107/673 (15%)

Query: 170 LSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPP-GPSEQVGPSQFHLEPETQNPE 228
           LS  + Q+   Q  +   D P PG +P EL    + PP  P   + PSQ ++ P      
Sbjct: 115 LSYQKQQQYKHQMLHHQRDGP-PGLVPMELESPPESPPVPPGSYMPPSQSYMPPP----- 168

Query: 229 TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
                      Q  P+  P      P+S Q   P LPP     S + P+       P   
Sbjct: 169 -----------QPPPSYYP------PTSSQ---PYLPPAQPSPSQSPPSQSYLAPTPSYS 208

Query: 289 QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +           +    +  S   +   SSQA    P Q       S +Q  AP  P  
Sbjct: 209 SS-----------SSSSQSYLSHSQSYLPSSQASPSRPSQ-----GHSKSQLLAPPPPSA 252

Query: 349 PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHL 405
           PP       + QQ+P+   ES  + +S+  QQ  P   P     T++P    Q     HL
Sbjct: 253 PPGN---KTTVQQEPL---ESGAKNKSTEQQQAAPEPDPS----TMTPQEQQQYWYRQHL 302

Query: 406 ASPSVSVK---PPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
            S     K   P   +  + A+ + E     V   AT+++  S +  EPP         L
Sbjct: 303 LSLQQRTKVHLPGHKKGPVVAKDTPEPVKEEVTVPATSQVPESPSSEEPP---------L 353

Query: 463 PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQT 522
           P  +EE  P    +E   + PE    E+    Q +AAA H Q  ++      +Q    + 
Sbjct: 354 PPPNEEVPPPLPPEEPQSEDPE----EDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKH 409

Query: 523 PEFPNVV-----VAQPPEHSHLTQATVQPLDLGFTITP----ESKTEVELSPTMKETPTQ 573
            +   ++     + QPP H       +Q                + E E     ++  + 
Sbjct: 410 TQLQQILQQYQQIIQPPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSY 469

Query: 574 PPKKVVP----QLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHST 629
           P K  +     Q + +QG    T  Q   Q  V+    ++   +G    P P        
Sbjct: 470 PHKDQLQEYEKQWKTWQGHMKAT--QSYLQEKVNSFQNMKNQYMGNMSMPPPFVPYSQMP 527

Query: 630 PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTT 689
           PP  T+  P  P  +LP P              V P  L  T+ P  M       +L T+
Sbjct: 528 PPLPTMPPPVLPP-SLPPP--------------VMPPALPATVPPPGMPPPVMPPSLPTS 572

Query: 690 APPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSP----TTEETS 745
            PPPG P                L+ A   P+    ++++     V P P     T    
Sbjct: 573 VPPPGMPPSLSSAGPPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPG 632

Query: 746 TQPPDLGLAIIPEPT-TETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSL 804
             PP +   I P+ T      +++ + +  P   R   L   ++  + PPT   P   S 
Sbjct: 633 IPPPGVPQGIPPQLTAAPVPPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQSA 692

Query: 805 VQSESYTQNKALT 817
             SE       L+
Sbjct: 693 GPSEQVNSKAPLS 705



 Score = 42.7 bits (99), Expect = 0.003
 Identities = 121/579 (20%), Positives = 198/579 (34%), Gaps = 69/579 (11%)

Query: 46  PLQLTSNPLGPPEPWSSH----SSHFPRESP---HAPTLPADPWDFDHLGPSASSEMPAP 98
           P++L S P  PP P  S+     S+ P   P   + P   + P+    L P+  S   +P
Sbjct: 140 PMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPY----LPPAQPSPSQSP 195

Query: 99  PQESTENLVPFLDTWDSAGELPLEPEQ-FLASQQDLKDKLSP--QERLPVSPKKLKKDPA 155
           P +S     P   +  S+ +  L   Q +L S Q    + S    +   ++P      P 
Sbjct: 196 PSQSYLAPTPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPPPPSAPPG 255

Query: 156 QRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGP 215
            + ++ +       L +    K T Q +  +   P P ++ P+ + +             
Sbjct: 256 NKTTVQQ-----EPLESGAKNKSTEQQQ--AAPEPDPSTMTPQEQQQYWYRQHLLSLQQR 308

Query: 216 SQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTL 275
           ++ HL    + P   +D     +++E        + E PSS   E P LPP +      L
Sbjct: 309 TKVHLPGHKKGPVVAKDTPEP-VKEEVTVPATSQVPESPSS---EEPPLPPPNEEVPPPL 364

Query: 276 PNHEVSVQPPGED-------QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQ 328
           P  E   + P ED        A  H           +     +   + +    Q +  IQ
Sbjct: 365 PPEEPQSEDPEEDARLKQLQAAAAHWQQHQQHRVGFQYQGIMQKHTQLQQILQQYQQIIQ 424

Query: 329 FPEEVEPSAT--------QQEAPIEPPVPPMEHELSISEQQQPVQP-SESPREVESS-PT 378
            P  ++  +          Q+   +      E E  + E+Q    P  +  +E E    T
Sbjct: 425 PPPHIQTMSVDMQLRHYEMQQQQFQHLYQEWEREFQLWEEQLHSYPHKDQLQEYEKQWKT 484

Query: 379 QQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQE- 437
            Q        + +  V+   + +  ++   ++S+ PP V  +    P   +   ++    
Sbjct: 485 WQGHMKATQSYLQEKVNSFQNMKNQYMG--NMSMPPPFVPYSQMPPPLPTMPPPVLPPSL 542

Query: 438 ----------ATTRLSGSGNDVEPPAIQHG-GPPLLPESSEEAGPLAVQQETSFQS--PE 484
                     AT    G    V PP++     PP +P S   AGP  V    S  S  P 
Sbjct: 543 PPPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPVLPPPSLSSAGPP 602

Query: 485 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
           P+      P    + A  P       SS T    P   P  P V    PP+   LT A V
Sbjct: 603 PV----LPPPSLSSTAPPPVMPLPPLSSAT--PPPGIPP--PGVPQGIPPQ---LTAAPV 651

Query: 545 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLR 583
            P     +     K    L PT     + PP    P L+
Sbjct: 652 PPASSSQSSQVPEKPRPALLPTPVSFGSAPPTTYHPPLQ 690


>gi|238624188 diffuse panbronchiolitis critical region 1 protein [Homo
            sapiens]
          Length = 1393

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 162/809 (20%), Positives = 282/809 (34%), Gaps = 115/809 (14%)

Query: 37   AQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMP 96
            A+P E  +      + P  P EP + H      E+   P+ PA+P +     P A+ +  
Sbjct: 359  AEPTEHGERTANENTTP-SPAEP-TEHGERTANENT-TPS-PAEPTEHGERTPFANDKTT 414

Query: 97   APPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPA- 155
            +   ESTE+        ++    P EP +    ++   +  +P    P  P + ++  A 
Sbjct: 415  SSSAESTEHGERTPLANENTTPSPAEPTE--NRERTANENTTPS---PAGPTENRETTAN 469

Query: 156  QRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYP---GSLPPELRVK----SDEPPG 208
            ++ +L+ +         P   ++T  NE ++     P   G   P    K    S EP  
Sbjct: 470  EKTTLSPV--------EPTENRETTANEKTTPSPAEPTENGQRTPFANEKTTSSSAEPTE 521

Query: 209  PSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALP-PE 267
              E+   +  +  P    P    +  ++     +PA+  +  +  P + ++  P+L  P 
Sbjct: 522  HGERTPLANENTTPSPAEPTENRERTANEKTTPSPAEPTENGDRTPLANEKTTPSLAEPT 581

Query: 268  SSMESLTLPNHEV--SVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQET 325
             + +     N +   S   P E +    L N    P+       +EPT   E +  +  T
Sbjct: 582  ENGQRTPFANEKTTSSSAEPTEHEERTPLANENTTPSP------AEPTENRERTANENTT 635

Query: 326  PIQF-PEEVEPSATQQEAPIEPPVPPMEHELSISEQ--QQPVQPSESPREVESSPTQQET 382
            P    P E       ++  + P  P    E + +E+    P +P+E+          Q T
Sbjct: 636  PSPAGPTENREMTANEKTTLFPAEPTENRERTANEKTTSSPAEPTENG---------QRT 686

Query: 383  PGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRL 442
            P    +    +  P  H +   LA+ + ++ P +   T   E +A   T+    E T   
Sbjct: 687  PFANEKTTSSSAEPTEHGERTPLANENTTLSPAEP--TENRERTANEKTTPFPAEPTENR 744

Query: 443  SGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEH 502
              + N+   P+      P  P  + +  PLA  ++T+    EP  N   +P   E     
Sbjct: 745  ERTANENTTPS------PAQPTENGDRTPLA-NEKTTPSLAEPTENGKRTPFANEKTTS- 796

Query: 503  PQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVE 562
                    SS    E   +TP       + P E +   + T       F   P    E  
Sbjct: 797  --------SSAEPTEHAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENREST 848

Query: 563  LSPTMKETPTQPPKKVVPQLRVYQGVTNPT--PGQDQAQHPVSPSVTVQLLDLGLTITPE 620
             +      P +P +      R +    N T  P +      ++P     L +   T++P 
Sbjct: 849  ANEKTTPFPAEPTEN-----REWTANENTTLSPAEPTEHEEMTP-----LANEKTTLSPA 898

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEV 680
              TE G  TP      +P   E T  H ++    +   T +  +P + G  I  +  T  
Sbjct: 899  EPTENGERTPFTNEKTTPSSAEPT-EHGERTPLANEITTPSRAEPTEHGERIANEKATP- 956

Query: 681  EPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPT 740
                   + A P  H E T+         +   T ++ +P           T   + +P 
Sbjct: 957  -------SPAKPTEHGETTV---------NEDTTPSSAEP-----------TENGERTPL 989

Query: 741  TEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHR--SLTEVTGPPTELE 798
              E +T  P          +TE G  TA EKTT    +  +   R  S  E T P     
Sbjct: 990  ANENTTTSPT--------ESTEHGERTANEKTTPSPAEPTEHGERTPSANEKTIPSPAKP 1041

Query: 799  PAQDSLVQSESYTQNKALTAPEEHKASTS 827
               + +  S +     +   P EH   T+
Sbjct: 1042 TEHEEMTPSANENTTPSPVKPTEHGEKTT 1070



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 105/502 (20%), Positives = 176/502 (35%), Gaps = 78/502 (15%)

Query: 50   TSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDF-DHLGPSASSEMPAPPQESTENLVP 108
            TS+   P E    H+   P  + +  + PA+P +  +      +++ PA P E+ E+   
Sbjct: 795  TSSSAEPTE----HAERTPLANENTTSSPAEPTENRERTANEKTTQFPAEPTENRESTAN 850

Query: 109  FLDTWDSAGELPLEPEQFLASQQDLKDKLSP---QERLPVSPKKLKKDPAQRWSLAEIIG 165
               T   A   P E  ++ A++        P   +E  P++ +K    PA+     E   
Sbjct: 851  EKTTPFPAE--PTENREWTANENTTLSPAEPTEHEEMTPLANEKTTLSPAEPTENGERTP 908

Query: 166  IIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPE-- 223
               + +TP S + T   E     TP    +    R    EP    E++   +    P   
Sbjct: 909  FTNEKTTPSSAEPTEHGER----TPLANEITTPSRA---EPTEHGERIANEKATPSPAKP 961

Query: 224  TQNPETL--EDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVS 281
            T++ ET   ED   SS +     +   L  E  ++        P ES+       N + +
Sbjct: 962  TEHGETTVNEDTTPSSAEPTENGERTPLANENTTTS-------PTESTEHGERTANEKTT 1014

Query: 282  VQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQE----TPIQFPEEVEPSA 337
              P    +     P+   K     +   ++PT   E + +  E    +P++  E  E + 
Sbjct: 1015 PSPAEPTEHGERTPSANEKT----IPSPAKPTEHEEMTPSANENTTPSPVKPTEHGEKTT 1070

Query: 338  TQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP- 396
               E     P  P EH    +   + + PS +               +P EH E T SP 
Sbjct: 1071 LANEKITLSPEGPTEHGAKTTSANEKITPSLA---------------KPTEHGERTTSPN 1115

Query: 397  ------PGHHQTHHLASPSVSVKPP--------DVQLTIAAEPSAEV-GTSLVHQEATTR 441
                        H   + S +V  P          + T+A E   +V   S  H E TT 
Sbjct: 1116 DKITSSAAESTEHRDRATSANVITPAPAEPIKHAKRTTLAHEKMTQVTEKSTEHPEKTTS 1175

Query: 442  LS-GSGNDVEPPAI--------QHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPS 492
             +  +    E P +        +    P+  + +E  G   +  ET  ++P   + ENP 
Sbjct: 1176 TTEKTTRTPEKPTLYSEKTICTKGKNTPVPEKPTENLGNTTLTTET-IKAPVK-STENPE 1233

Query: 493  PTQQEAAAEHPQTAEEGESSLT 514
             T        P     G+ SLT
Sbjct: 1234 KTAAVTKTIKPSVKVTGDKSLT 1255



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 70/333 (21%), Positives = 118/333 (35%), Gaps = 51/333 (15%)

Query: 475 QQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPP 534
           +  T      P + EN S   ++    + ++ +  +S+ TH+E+  +             
Sbjct: 109 KSSTDNHEAPPTSEENSSNQGKDPMIRNQRSVDPADSTTTHKESAGK------------- 155

Query: 535 EHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG 594
              H+T A            P+SK     S T K T T+   K    L       + T  
Sbjct: 156 --KHITPA------------PKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTST 201

Query: 595 QDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ 654
                   S   T    + G + T + +T    S P K T  S    + T    +  +T+
Sbjct: 202 S-------SHKTTTSFHNSGNSQTKQKST----SFPEKITAASKTTYKTTGTPEESEKTE 250

Query: 655 HSHLTRATVQPL-----DLGFTITPKSMTE--VEPSTALMTTAPPPGHPEVTLPPSDKGQ 707
            S  T A+ + L     ++  TI+   +T+   EP+     TA     P    P  ++ +
Sbjct: 251 DSRTTVASDKLLTKTTKNIQETISANELTQSLAEPTEHGGRTANENNTPSPAEPTENRER 310

Query: 708 AQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHST 767
             + + T +  +P++       + T      PT  E      +    + P   TE G  T
Sbjct: 311 TANENTTLSPAEPIENRERTANENTAPFPAGPT--ENREMTANENTTLFPAEPTEHGERT 368

Query: 768 ALEKTTAPRPDRVQTLHRSLTEVTGP----PTE 796
           A E TT    +  +   R+  E T P    PTE
Sbjct: 369 ANENTTPSPAEPTEHGERTANENTTPSPAEPTE 401



 Score = 35.0 bits (79), Expect = 0.60
 Identities = 43/182 (23%), Positives = 75/182 (41%), Gaps = 17/182 (9%)

Query: 638 PKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVE--PSTALMTTAPPPGH 695
           P+ P+ T  H  +     +  ++ T +P     TI  KS T+    P T+   ++     
Sbjct: 72  PELPKSTEIHEQKRHCNTTRHSKPTDKPTGNSKTIDHKSSTDNHEAPPTSEENSSNQGKD 131

Query: 696 PEV----TLPPSD-----KGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE--ET 744
           P +    ++ P+D     K  A   H+T A    ++   + T K T   K   T    E 
Sbjct: 132 PMIRNQRSVDPADSTTTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEK 191

Query: 745 STQPPDLGLAIIPEPTTE---TGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQ 801
           S    D       + TT    +G+S   +K+T+  P+++    ++  + TG P E E  +
Sbjct: 192 SMSTLDKTSTSSHKTTTSFHNSGNSQTKQKSTS-FPEKITAASKTTYKTTGTPEESEKTE 250

Query: 802 DS 803
           DS
Sbjct: 251 DS 252


>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
          Length = 1427

 Score = 75.5 bits (184), Expect = 4e-13
 Identities = 142/628 (22%), Positives = 217/628 (34%), Gaps = 87/628 (13%)

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
            D Q++ L+ +APA   +     P  + Q+     PES + SL L   E+ + P G +   
Sbjct: 725  DYQATLLEDQAPAHFHRNF---PEQVFQDLQRKSPESEILSLHLLVEELRLNPDGVE--- 778

Query: 292  YHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPM 351
                  TV     E+ + S    E E   +     I FPE+    A   E  +E  +P +
Sbjct: 779  ------TVNDTKPELNVASSEGGEMERRDSDSFLNI-FPEKQVTKAGNTEPVLEEWIPVL 831

Query: 352  EHEL------SISEQQQPVQPS-ESPREVESSPTQQETPG----QPPEHHEVTVSPPGHH 400
            +         ++ +      PS E    + + P  + T       P  H ++ V+     
Sbjct: 832  QRPSRTAAVPTVKDALDAALPSPEEGTSIAAVPAPEGTAVVAALVPFPHEDILVASIVSL 891

Query: 401  QTHHLAS-----------PSVSVKPPDVQLTIAA----EPSAEVGTSLVHQEATTRLSGS 445
            +   + +           P+V+V  P+    +AA    E +A    + + QE  + ++G 
Sbjct: 892  EEEDVTAAAVSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGF 951

Query: 446  GNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP-EPINNENPSPTQQEAAAEHPQ 504
              +    AI     P+  E     GP  V   T+  +P EP        T +E A+  P 
Sbjct: 952  SPEWAALAIT---VPITEEDGTPEGP--VTPATTVHAPEEPDTAAVRVSTPEEPAS--PA 1004

Query: 505  TAEEGESSLTHQEAPAQTPEFP-NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVEL 563
             A       T   A   TPE P +   A PP     + A   P       TPE  T    
Sbjct: 1005 AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP-------TPEEPTSPAA 1057

Query: 564  SPTMKETPTQPPKKV-VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPT 622
            +    E PT P   V  P+         PTP     + P SP+  V         TPE  
Sbjct: 1058 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP-----EEPTSPAAAVP--------TPEEP 1104

Query: 623  TEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
            T    + P   T   P  P   +P P++  +       A   P +  F        E   
Sbjct: 1105 TSPAAAVP---TPEEPASPAAAVPTPEEPASP----AAAVPTPEEPAFPAPAVPTPEESA 1157

Query: 683  STALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTK----PTTEVKPS 738
            S A+    P          P+    A  + +     +P     ++ T      T E   S
Sbjct: 1158 SAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTS 1217

Query: 739  PTTE-ETSTQPPDLGLAII--PEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPT 795
            P     TS +P  L  A+    EPT+       LE+ T+     V T     +     PT
Sbjct: 1218 PAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAA-AVLTPEELSSPAASVPT 1276

Query: 796  ELEPAQDSLVQS---ESYTQNKALTAPE 820
              EPA  +   S   E  +   A+  PE
Sbjct: 1277 PEEPASPAAAVSNLEEPASPAAAVPTPE 1304



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 90/376 (23%), Positives = 129/376 (34%), Gaps = 51/376 (13%)

Query: 169  QLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
            ++STP+          ++  TP   + P       +EP  P+  V P +    P    P 
Sbjct: 993  RVSTPEEPASPA----AAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVP- 1047

Query: 229  TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
            T E+  S +     P        EEP+S     P  P E +  +  +P  E    P    
Sbjct: 1048 TPEEPTSPAAAVPTP--------EEPTSPAAAVPT-PEEPTSPAAAVPTPEEPTSPA--- 1095

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
             A    P     PA       + PT E  +S A     +  PEE    A     P EP  
Sbjct: 1096 -AAVPTPEEPTSPA------AAVPTPEEPASPA---AAVPTPEEPASPAAAVPTPEEPAF 1145

Query: 349  P----PMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHH 404
            P    P   E + +    P  P ES     + PT  E+          T+  P       
Sbjct: 1146 PAPAVPTPEESASAAVAVPT-PEESASPAAAVPTPAESASFAAV--VATLEEP------- 1195

Query: 405  LASPSVSVKPPDVQLTIAAE---PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPL 461
              SP+ SV  P   +    E   P+A V TS   +E  +  +   N  EP +     P L
Sbjct: 1196 -TSPAASVPTPAAMVATLEEFTSPAASVPTS---EEPASLAAAVSNPEEPTSPAAAVPTL 1251

Query: 462  LPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPA- 520
               +S  A  L  ++ +S  +  P   E  SP    +  E P +      +      PA 
Sbjct: 1252 EEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAA 1311

Query: 521  --QTPEFPNVVVAQPP 534
               TPE P +  A  P
Sbjct: 1312 SVPTPEVPAIPAAAVP 1327



 Score = 36.6 bits (83), Expect = 0.20
 Identities = 62/294 (21%), Positives = 101/294 (34%), Gaps = 47/294 (15%)

Query: 39   PLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAP 98
            P   V  P +  S     P P    S      +P  P  PA          SA+  +P P
Sbjct: 1107 PAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTP 1166

Query: 99   PQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRW 158
             + ++           +A   P E   F A    L++  SP   +P              
Sbjct: 1167 EESASP---------AAAVPTPAESASFAAVVATLEEPTSPAASVPTP------------ 1205

Query: 159  SLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQF 218
              A ++  + + ++P +   T +          P SL   +    +EP  P+  V   + 
Sbjct: 1206 --AAMVATLEEFTSPAASVPTSEE---------PASLAAAVS-NPEEPTSPAAAVPTLE- 1252

Query: 219  HLEPETQ-----NPETLEDIQSSSLQQEAPAQLPQLLE--EEPSSMQQEAP----ALPPE 267
              EP +       PE L    +S    E PA     +   EEP+S     P    A  P 
Sbjct: 1253 --EPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPA 1310

Query: 268  SSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQA 321
            +S+ +  +P    +  PP E+ +   +P + V      V I+ E T   E + +
Sbjct: 1311 ASVPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEEASS 1364


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 170/799 (21%), Positives = 264/799 (33%), Gaps = 80/799 (10%)

Query: 59   PWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE 118
            P S+ ++HFP  S  +    ++     H  P AS   P+    +T        +  S G 
Sbjct: 2251 PGSTPTTHFPASSTTSGH--SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 2308

Query: 119  LPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQ 178
              +       +   L +  +     P SP      PA   SL    G+  + +T +SQ  
Sbjct: 2309 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSL----GVGEESTTSRSQPG 2363

Query: 179  TLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQV------------GPSQFHLEP-ETQ 225
            +  +  S   T  PG       V S  P      V             P+ FH  P  T 
Sbjct: 2364 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTH 2423

Query: 226  NPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSM--ESLTLPNHEVSVQ 283
                 ED  +S L +E+ A         P+S Q   PA    + +  ES T P+   S  
Sbjct: 2424 TTLFTEDSTTSGLTEESTA-----FPGSPASTQTGLPATLTTADLGEESTTFPSSSGST- 2477

Query: 284  PPGEDQAYYHLPNITVKPADVEVT-ITSEPTNETESSQAQQETPI----QFPEEVEPSAT 338
                          T+ PA    + +  E T    S  + + T +      P   E S T
Sbjct: 2478 ------------GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTT 2525

Query: 339  QQEAPIEPPV---PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVS 395
               +P  P     P       +SE+              + P    TPG    H   + S
Sbjct: 2526 FYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGL-SRHSTTSHS 2584

Query: 396  PPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQ 455
             PG   T  L + + +  P     T  + P +   T+L     T    G  +     +  
Sbjct: 2585 SPGSTDTTLLPASTTTSGPSQESTTSHSSPGS-TDTALSPGSTTALSFGQESTTFHSSPG 2643

Query: 456  HGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTH 515
                 L P+S+  +G   V+  T   S    +  +P  T   A++  P    E  +  TH
Sbjct: 2644 STHTTLFPDSTTSSG--IVEASTRVHS----STGSPRTTLSPASSTSPGLQGESTTFQTH 2697

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPP 575
              +   TP  P+   A   E +   ++        F  +  +    E S     +P    
Sbjct: 2698 PASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA-- 2755

Query: 576  KKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTI 635
                       G T  +     +    S +  +      +T  P  TT  G S       
Sbjct: 2756 ----------SGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 2805

Query: 636  VSPKHPEVTLPHPDQVQT-QHSHLTRATVQPLDLGFTITPKSMTE---VEPSTALMTTAP 691
             SP+ P  TL              T +  QP     T++P S T     E ST + +++ 
Sbjct: 2806 SSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS- 2864

Query: 692  PPGHPEVTL-PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPD 750
             PG  E T+ P S     +    T    +P     T+ T+ +T    S  TEE++  P  
Sbjct: 2865 -PGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDST---TSGLTEESTAFPGS 2920

Query: 751  LGLAIIPEPTTETGHSTALEKTTAPRP--DRVQTLHRSLTEVTGPPTELEPAQDSLVQSE 808
                    P T T      E TT P        TL  + +  +G   E  P++ S   +E
Sbjct: 2921 PASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTE 2980

Query: 809  SYTQNKALTAPEEHKASTS 827
            + T   + T P   + ST+
Sbjct: 2981 TTTLPGSPTTPSLSEKSTT 2999



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 197/872 (22%), Positives = 276/872 (31%), Gaps = 174/872 (19%)

Query: 59   PWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE 118
            P S+ ++HFP  S  +    ++     H  P AS   P+    +T        +  S G 
Sbjct: 2725 PGSTPTTHFPASSTTSGH--SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 2782

Query: 119  LPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQ 178
              +       +   L +  +     P SP      PA   SL    G+  + +T +SQ  
Sbjct: 2783 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSL----GVGEESTTSRSQPG 2837

Query: 179  TLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQV------------GPSQFHLEP-ETQ 225
            +  +  S   T  PG       V S  P      V             P+ FH  P  T 
Sbjct: 2838 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTH 2897

Query: 226  NPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSM--ESLTLPNHEVSVQ 283
                 ED  +S L +E+ A         P+S Q   PA    + +  ES T P+   S  
Sbjct: 2898 TTLFTEDSTTSGLTEESTA-----FPGSPASTQTGLPATLTTADLGEESTTFPSSSGS-- 2950

Query: 284  PPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP 343
                                     T  P   T S    + T    P  + PS+T+    
Sbjct: 2951 ----------------------TGTTLSPARSTTSGLVGEST----PSRLSPSSTETTTL 2984

Query: 344  IEPPVPPMEHELSISEQQQPVQPSE--SPREVESSPTQQETP---GQPPEHHEVTVSPPG 398
               P  P   E S +    P  P    SP    SS   +E+     QP   H  T + P 
Sbjct: 2985 PGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH--TTAFPD 3042

Query: 399  HHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND---------- 448
               T  L+    +             P +   +SL  Q++TT  S  G+           
Sbjct: 3043 STTTSGLSQEPTASHSSQGSTEATLSPGSTTASSL-GQQSTTFHSSPGDTETTLLPDDTI 3101

Query: 449  ----VEPPAIQHGG-----PPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAA 499
                VE     H         L P SS  AG    ++ T+FQS    ++  PSP    AA
Sbjct: 3102 TSGLVEASTPTHSSTGSLHTTLTPASSTSAG--LQEESTTFQSWPSSSDTTPSPPGTTAA 3159

Query: 500  AEHPQTAEEGESS---LTHQEAPAQT---PEFPNVVVAQP--------PEHSHLT----Q 541
                 T      S    TH  A + T    E    V + P        P  S  +    +
Sbjct: 3160 PVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGE 3219

Query: 542  ATVQPLDLGFTIT---PESKTEV---ELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQ 595
             T  P+  G T T   P S T     E S T   +P  P   + P      GV+     +
Sbjct: 3220 PTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVS-----E 3274

Query: 596  DQAQHPVSPSVTVQLLDLGLTITPEPTTE--VGHSTP--------PKRTIVSPKHPEVTL 645
            +       P  T      G T  P  + E    HS+P        P  T  S   PE T 
Sbjct: 3275 ESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTT 3334

Query: 646  PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDK 705
             H     T+       T+ P +   +   ++ T V  ST         G P  TL P+  
Sbjct: 3335 FHSGPGSTE------TTLLPDNTTASGLLEASTPVHSST---------GSPHTTLSPAGS 3379

Query: 706  GQAQHSHLT-------------QATVQPLDLELTIT------TKPTTEVKPSPTT----- 741
               Q    T               T     +EL+ T      + PTT    S TT     
Sbjct: 3380 TTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 3439

Query: 742  EETSTQPPDLGLAIIPEPTTETGHSTALEKTT-APRPDRVQTLHRSLTEVTGPPTELEPA 800
            E T+     +  A  P P   T      E TT    P   QT+H   ++ T    E    
Sbjct: 3440 ESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGE---- 3495

Query: 801  QDSLVQSESYTQNKALTAPEEHKASTSTNICE 832
                   ES T + + T       ST++ + E
Sbjct: 3496 -------ESTTSHSSTTHTISSAPSTTSALVE 3520



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 174/828 (21%), Positives = 257/828 (31%), Gaps = 118/828 (14%)

Query: 59   PWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGE 118
            P S+ ++HFP  S  +    ++     H  P AS   P+    +T        +  S G 
Sbjct: 3808 PGSTPTTHFPASSTTSGH--SEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGS 3865

Query: 119  LPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQ 178
              +       +   L +  +     P SP      PA   SL    G+  + +T +SQ  
Sbjct: 3866 TEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS-PASMTSL----GVGEESTTSRSQPG 3920

Query: 179  TLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSL 238
            +  +  S   T  PG       V S  P      V P         + P T         
Sbjct: 3921 STHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRREEPTTF-------- 3972

Query: 239  QQEAPAQLPQLLEEEPSS---MQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLP 295
                PA     L  E S+   + +E+ A P   +     LP   ++    GE+       
Sbjct: 3973 -HSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLP-ATLTTADLGEES------ 4024

Query: 296  NITVKPADVEVTITS-EPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHE 354
              T  P+    T T   P   T S    + T    P  + PS+T+       P  P   E
Sbjct: 4025 --TTFPSSSGSTGTKLSPARSTTSGLVGEST----PSRLSPSSTETTTLPGSPTTPSLSE 4078

Query: 355  LSISEQQQPVQPSE--SPREVESSPTQQETP---GQPPEHHEVTVSPPGHHQTHHLASPS 409
             S +    P  P    SP    SS   +E+     QP   H  T + P    T  L+   
Sbjct: 4079 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH--TTAFPDSTTTSGLSQEP 4136

Query: 410  VSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEA 469
             +             P +   +SL  Q  +T    S  D E          LLP+ +  +
Sbjct: 4137 TTSHSSQGSTEATLSPGSTTASSLGQQ--STTFHSSPGDTE--------TTLLPDDTITS 4186

Query: 470  GPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFP--- 526
            G +     T   +        P+ +      E   T +   SS     +P  T   P   
Sbjct: 4187 GLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEV 4246

Query: 527  NVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQ 586
            +      P  +  T  +     LG     E  T V  SP    T   P +     L    
Sbjct: 4247 STTYHSRPSSTPTTHFSASSTTLG---RSEESTTVHSSPGATGTALFPTRSATSVL---- 4299

Query: 587  GVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTL- 645
             V  PT        P+S   T        T  P  TT  G S        SP+ P+ TL 
Sbjct: 4300 -VGEPTTS------PISSGST------ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLS 4346

Query: 646  PHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPP--- 702
            P            T +  +P  +  T  P S T    S     +   PG  + TL P   
Sbjct: 4347 PASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGST 4406

Query: 703  -------------SDKGQAQHSHLTQATVQPLDLELTI-----TTKPTTEVKPS------ 738
                         S  G  + + L   T     LE +      T  P T + P+      
Sbjct: 4407 TASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQ 4466

Query: 739  ---------PTTEETSTQPPDLGLAIIPEPTTETGHST-------ALEKTTAPRPDRVQT 782
                     P +++T+  PP    A +   TT  G  +       +   TT  R +   T
Sbjct: 4467 GESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTT 4526

Query: 783  LHRSLTEVTGPPTELEPAQDSLV-QSESYTQNKALTAPEEHKASTSTN 829
            +H S       P+        LV +S +Y  +   T       S +T+
Sbjct: 4527 VHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTS 4574



 Score = 69.3 bits (168), Expect = 3e-11
 Identities = 131/617 (21%), Positives = 202/617 (32%), Gaps = 62/617 (10%)

Query: 185  SSTDTPYPGS-LPPELRVKSD----EPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
            S+  T  PGS   P L  KS      P  P          L P T     + +  S+S  
Sbjct: 1421 STETTTLPGSPTTPSLSEKSTTFYTSPRSPDAT-------LSPATTTSSGVSEESSTSHS 1473

Query: 240  QEAPAQLPQLLEEEPSS-MQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNIT 298
            Q          +   +S + QE             TL     +    G+    +H     
Sbjct: 1474 QPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHS---- 1529

Query: 299  VKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSIS 358
              P D E T+   P +   S   +  TP         S       + P         S  
Sbjct: 1530 -SPGDTETTLL--PDDTITSGLVEASTP------THSSTGSLHTTLTPA-----SSTSAG 1575

Query: 359  EQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQ 418
             Q++       P   +++P+   T   P E      S P    T H ++ S ++   +  
Sbjct: 1576 LQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEES 1635

Query: 419  LTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQET 478
             T+ + P A  GT+L    + T +        P +        LP S+  AG L+ +  T
Sbjct: 1636 TTVHSSPGA-TGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAG-LSEKSTT 1693

Query: 479  SFQSP-EPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHS 537
             + SP  P    +P+ T     +E   T+     S TH  A   +   P V       HS
Sbjct: 1694 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS-THTTAFPGSTTMPGVSQESTASHS 1752

Query: 538  HLTQATVQPLDLGFTITPESKTEVELSP---TMKETPTQPPKKVVPQLRVYQGVTN-PTP 593
                    P     T++P S T   L P   T   +P      ++P      G+    TP
Sbjct: 1753 -------SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTP 1805

Query: 594  GQDQAQHP---VSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQ 650
                   P   +SP+ +        T    P+++     PP  T    +    +   P  
Sbjct: 1806 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSS 1865

Query: 651  VQTQHSHLTRATVQPLDLGFTITPKSM-TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQ 709
              T H   +  T+   +   T+    + T   PS A  TT+      E T   S  G  Q
Sbjct: 1866 TPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV--EESTAYHSSPGSTQ 1923

Query: 710  HSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTAL 769
              H  +++        T + +         +T  T + PP    A++ EPT+   HS+  
Sbjct: 1924 TMHFPESS--------TASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSY--HSSPG 1973

Query: 770  EKTTAPRPDRVQTLHRS 786
               T   PD   T  RS
Sbjct: 1974 STATTHFPDSSTTSGRS 1990



 Score = 68.9 bits (167), Expect = 4e-11
 Identities = 153/705 (21%), Positives = 232/705 (32%), Gaps = 102/705 (14%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            +P +   +  +E SST    PGS        S   PG S     S  H  P + +   L 
Sbjct: 2538 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTS--HSSPGSTDTTLLP 2595

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
                +S     P+Q        P S      AL P S+           ++    E   +
Sbjct: 2596 ----ASTTTSGPSQESTTSHSSPGSTDT---ALSPGST----------TALSFGQESTTF 2638

Query: 292  YHLPNITVKPADVEVTITS---EPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +  P  T      + T +S   E +    SS     T +       P   Q E+      
Sbjct: 2639 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL-QGESTTFQTH 2697

Query: 349  PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408
            P   H         P  PS +   VE S T   +PG  P  H     P     + H    
Sbjct: 2698 PASTHTT-------PSPPSTATAPVEESTTYHRSPGSTPTTH----FPASSTTSGHSEKS 2746

Query: 409  SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEE 468
            ++    PD   T  +  SA   TS   +  T+R+S    ++            LP S+  
Sbjct: 2747 TIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGSTEITT----------LPGSTTT 2794

Query: 469  AGPLAVQQETSFQSPE-PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP---- 523
             G L+    T + SP  P    +P+        E   T+     S     +PA T     
Sbjct: 2795 PG-LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 2853

Query: 524  -EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM--------------- 567
             E    V +  P     T+ TV P     ++  E  T     P                 
Sbjct: 2854 SEESTTVYSSSPGS---TETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSGL 2910

Query: 568  -KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE-- 624
             +E+   P      Q  +   +T    G++    P S   T      G T++P  +T   
Sbjct: 2911 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST------GTTLSPARSTTSG 2964

Query: 625  -VGHSTPPKRTIVSPKHPEVT-LPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
             VG STP +   +SP   E T LP      +     T     P     T++P + T    
Sbjct: 2965 LVGESTPSR---LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 3021

Query: 683  STALMTTAPPPGHPEVTLPP--------SDKGQAQHSHL--TQATVQPLDLELTITTKPT 732
            S    T+   PG    T  P        S +  A HS    T+AT+ P     +   + +
Sbjct: 3022 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQS 3081

Query: 733  TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHST-ALEKTTAPRPDRVQTLHRSLTEVT 791
            T    SP   ET+  P D   + + E +T T  ST +L  T  P       L    T   
Sbjct: 3082 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQ 3141

Query: 792  GPPTELEPAQD------SLVQSESYTQNKALTAPEEHKASTSTNI 830
              P+  +          + V+  +   ++  + P  H +++ST +
Sbjct: 3142 SWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 3186



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 151/705 (21%), Positives = 229/705 (32%), Gaps = 102/705 (14%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            +P S   +  +E S+T    PGS        S   PG S     S  H  P + +   L 
Sbjct: 3621 SPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTS--HSSPGSTDTTLLP 3678

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
               ++S                  S Q+   +     S ++   P    ++    E   +
Sbjct: 3679 ASTTTS-----------------GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 3721

Query: 292  YHLPNITVKPADVEVTITS---EPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +  P  T      + T +S   E +    SS     T +       P   Q E+      
Sbjct: 3722 HSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL-QGESTAFQTH 3780

Query: 349  PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408
            P   H         P  PS +   VE S T   +PG  P  H     P     + H    
Sbjct: 3781 PASTHTT-------PSPPSTATAPVEESTTYHRSPGSTPTTH----FPASSTTSGHSEKS 3829

Query: 409  SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEE 468
            ++    PD   T  +  SA   TS   +  T+R+S    ++            LP S+  
Sbjct: 3830 TIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGSTEITT----------LPGSTTT 3877

Query: 469  AGPLAVQQETSFQSPE-PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTP---- 523
             G L+    T + SP  P    +P+        E   T+     S     +PA T     
Sbjct: 3878 PG-LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGL 3936

Query: 524  -EFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM--------------- 567
             E    V +  P     T+ TV P     ++  E  T     P                 
Sbjct: 3937 SEESTTVYSSSPGS---TETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGL 3993

Query: 568  -KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE-- 624
             +E+   P      Q  +   +T    G++    P S   T      G  ++P  +T   
Sbjct: 3994 TEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGST------GTKLSPARSTTSG 4047

Query: 625  -VGHSTPPKRTIVSPKHPEVT-LPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEP 682
             VG STP +   +SP   E T LP      +     T     P     T++P + T    
Sbjct: 4048 LVGESTPSR---LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGV 4104

Query: 683  STALMTTAPPPGHPEVTLPP--------SDKGQAQHSHL--TQATVQPLDLELTITTKPT 732
            S    T+   PG    T  P        S +    HS    T+AT+ P     +   + +
Sbjct: 4105 SEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQS 4164

Query: 733  TEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHST-ALEKTTAPRPDRVQTLHRSLTEVT 791
            T    SP   ET+  P D   + + E +T T  ST +L  T  P       L    T   
Sbjct: 4165 TTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQ 4224

Query: 792  GPP----TELEPAQDSLVQSESYT--QNKALTAPEEHKASTSTNI 830
              P    T   P   + V  E  T   ++  + P  H +++ST +
Sbjct: 4225 SWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 170/827 (20%), Positives = 252/827 (30%), Gaps = 125/827 (15%)

Query: 66   HFPRESPHAPTLPADPWDFD------HLGPSASSEMPAPPQESTENLVPFLDTWDSAGEL 119
            H    SPH    PA            H  PS+    PAPP  ++  + P   +  S   +
Sbjct: 752  HSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPSTTSHGSPSSI 811

Query: 120  PLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQT 179
            P       ++   L ++ +     P                    G  + +  P+S   +
Sbjct: 812  PTTHISARSTTSGLVEESTTYHSSP--------------------GSTQTMHFPESDTTS 851

Query: 180  LQNEYSSTD----TPYPGSLPPELRVKSDEPPGPSEQVG-PSQFHLEPETQNPETLEDIQ 234
             + E S+T     T    S P       +EP       G  +  H    +      E+  
Sbjct: 852  GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 911

Query: 235  SSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPES-SMESLTLPNHEVSVQPPG--EDQAY 291
            +S   Q+A   +        S +  E+   P  S SME+  LP    S   PG  E    
Sbjct: 912  ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPG---STTTPGLSERSTT 968

Query: 292  YH----LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
            +H     P  T+ PA    +  SE +  + S      T   FP+        + +     
Sbjct: 969  FHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHT-TAFPDSTTTPGLSRHSTTSHS 1027

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
             P              + P+ +     S P+Q+ T          T   PG         
Sbjct: 1028 SP--------GSTDTTLLPAST---TTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQ 1076

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSE 467
             S +             P +   + +V  EA+TR+  S           G P      + 
Sbjct: 1077 ESTTFHSNPGSTHTTLFPDSTTSSGIV--EASTRVHSS----------TGSPRTTLSPAS 1124

Query: 468  EAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTA---EEGESSLTHQEAPAQT-- 522
               P    + T+FQ+     +  PSP     A     T      G +  TH  A + T  
Sbjct: 1125 STSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSG 1184

Query: 523  -PEFPNVVVAQP------PEHSH--------LTQATVQPLDLGFTITPESKTE---VELS 564
              E   +  + P      P  +H         T + + P     T  P S T     E S
Sbjct: 1185 HSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEAS 1244

Query: 565  PTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITP----E 620
             T   +P  P   + P      GV     G++       P  T   +    T TP    E
Sbjct: 1245 TTFYSSPRSPTTTLSPASMTSLGV-----GEESTTSRSQPGSTHSTVSPASTTTPGLSEE 1299

Query: 621  PTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHS-----HLTRATVQPLDLGF----T 671
             TT    S     T V P H   T  H ++  T HS     H T  T      G     T
Sbjct: 1300 STTVYSSSRGSTETTVFP-HSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEEST 1358

Query: 672  ITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLE-----LT 726
              P S    +       T    G    T P S           ++T   L  E     L+
Sbjct: 1359 AFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTPSRLS 1418

Query: 727  ITTKPTTEVKPSPTTEETS-------TQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDR 779
             ++  TT +  SPTT   S       T P      + P  TT +G S     T+  +P  
Sbjct: 1419 PSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEE-SSTSHSQPGS 1477

Query: 780  VQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKAST 826
              T     T      T  + +Q+      S    +A  +P    AS+
Sbjct: 1478 THT-----TAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASS 1519



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 140/695 (20%), Positives = 223/695 (32%), Gaps = 82/695 (11%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLE 231
            +P S   +  +E S+T    PGS        S   PG S     S  H  P + +   L 
Sbjct: 981  SPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTS--HSSPGSTDTTLLP 1038

Query: 232  DIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAY 291
               ++S                    Q+   +     S ++   P    ++    E   +
Sbjct: 1039 ASTTTS-----------------GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTF 1081

Query: 292  YHLPNITVKPADVEVTITS---EPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV 348
            +  P  T      + T +S   E +    SS     T +       P   Q E+      
Sbjct: 1082 HSNPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGL-QGESTAFQTH 1140

Query: 349  PPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASP 408
            P   H         P  PS +   VE S T   +PG  P  H     P     + H    
Sbjct: 1141 PASTHTT-------PSPPSTATAPVEESTTYHRSPGSTPTTH----FPASSTTSGHSEKS 1189

Query: 409  SVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEP-------PAIQHGGPPL 461
            ++    PD   T  +  SA   TS   +  T+R+S    ++         P +       
Sbjct: 1190 TIFHSSPDASGTTPS--SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTF 1247

Query: 462  LPESSEEAGPLAVQQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTHQ 516
                      L+    TS    E        P     T   A+   P  +EE  +  +  
Sbjct: 1248 YSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSS 1307

Query: 517  EAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPK 576
                +T  FP+            T  + +P     T+  E  T   L+   +E+   P  
Sbjct: 1308 RGSTETTVFPHSTTTSVHGEEPTTFHS-RPASTHTTLFTEDSTTSGLT---EESTAFPGS 1363

Query: 577  KVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE---VGHSTPPKR 633
                Q  +   +T    G++    P S   T      G  ++P  +T    VG STP + 
Sbjct: 1364 PASTQTGLPATLTTADLGEESTTFPSSSGST------GTKLSPARSTTSGLVGESTPSR- 1416

Query: 634  TIVSPKHPEVT-LPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPP 692
              +SP   E T LP      +     T     P     T++P + T    S    T+   
Sbjct: 1417 --LSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 1474

Query: 693  PGHPEVTLPP--------SDKGQAQHSHL--TQATVQPLDLELTITTKPTTEVKPSPTTE 742
            PG    T  P        S +    HS    T+AT+ P     +   + +T    SP   
Sbjct: 1475 PGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDT 1534

Query: 743  ETSTQPPDLGLAIIPEPTTETGHST-ALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQ 801
            ET+  P D   + + E +T T  ST +L  T  P       L    T     P+  +   
Sbjct: 1535 ETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTP 1594

Query: 802  D------SLVQSESYTQNKALTAPEEHKASTSTNI 830
                   + V+  +   ++  + P  H +++ST +
Sbjct: 1595 SPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 1629



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 176/808 (21%), Positives = 266/808 (32%), Gaps = 138/808 (17%)

Query: 62   SHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPL 121
            S +SH  +++     LPA       LG S +S + +   E+T   +P   T     E   
Sbjct: 1993 STASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA--LPGSTTTPGLSE--- 2047

Query: 122  EPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQ 181
            +   F +S +     LSP         +       R       G     + P S      
Sbjct: 2048 KSTTFHSSPRSPATTLSPASTTSSGVSEESTTSHSR------PGSTHTTAFPDSTTTPGL 2101

Query: 182  NEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEP-ETQNPETLEDIQSSSLQQ 240
            + +S+T    PGS    L   S    GPS++   S  H  P  T    +     + S  Q
Sbjct: 2102 SRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTS--HSSPGSTDTALSPGSTTALSFGQ 2159

Query: 241  EAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVK 300
            E+           P S       L P+S+  S  +   E S +      +    P  T+ 
Sbjct: 2160 ESTT-----FHSSPGSTH---TTLFPDSTTSSGIV---EASTRVHSSTGS----PRTTLS 2204

Query: 301  PADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQ 360
            PA      ++ P  + ES+  Q            P++T                      
Sbjct: 2205 PAS-----STSPGLQGESTAFQ----------THPAST---------------------H 2228

Query: 361  QQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLT 420
              P  PS +   VE S T   +PG  P  H     P     + H    ++    PD   T
Sbjct: 2229 TTPSPPSTATAPVEESTTYHRSPGSTPTTH----FPASSTTSGHSEKSTIFHSSPDASGT 2284

Query: 421  IAAEPSAEVGTSLVHQEATTRLSGSGNDV-------------EPPAIQHGGP--PLLPES 465
              +  SA   TS   +  T+R+S    ++             E     +  P  P    S
Sbjct: 2285 TPS--SAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 2342

Query: 466  SEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEF 525
                  L V +E++    +P +  +   T   A+   P  +EE  +  +      +T  F
Sbjct: 2343 PASMTSLGVGEESTTSRSQPGSTHS---TVSPASTTTPGLSEESTTVYSSSPGSTETTVF 2399

Query: 526  PNV----VVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQ 581
            P      V  + P   H      +P     T+  E  T   L+   +E+   P      Q
Sbjct: 2400 PRTPTTSVRGEEPTTFH-----SRPASTHTTLFTEDSTTSGLT---EESTAFPGSPASTQ 2451

Query: 582  LRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE---VGHSTPPKRTIVSP 638
              +   +T    G++    P S   T      G T++P  +T    VG STP +   +SP
Sbjct: 2452 TGLPATLTTADLGEESTTFPSSSGST------GTTLSPARSTTSGLVGESTPSR---LSP 2502

Query: 639  KHPE-VTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPE 697
               E  TLP      +     T     P     T++P + T    S    T+   PG   
Sbjct: 2503 SSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTH 2562

Query: 698  VT-LPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAII 756
             T  P S        H T +   P   + T+    TT   PS  +  + + P     A+ 
Sbjct: 2563 TTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALS 2622

Query: 757  PEPTT--------ETGHSTALEKTTAPRPDR------VQTLHRSLTEVTGPPTELEPAQD 802
            P  TT         T HS+     T   PD       V+   R  +    P T L PA  
Sbjct: 2623 PGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASS 2682

Query: 803  SL--VQSESYTQNKALTAPEEHKASTST 828
            +   +Q ES       T  + H AST T
Sbjct: 2683 TSPGLQGES-------TTFQTHPASTHT 2703



 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 143/682 (20%), Positives = 207/682 (30%), Gaps = 109/682 (15%)

Query: 184  YSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAP 243
            +SST +P     P        +    + Q  P+  H  P   +  T   ++ S+    +P
Sbjct: 2193 HSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAP-VEESTTYHRSP 2251

Query: 244  AQLP--QLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKP 301
               P         +S   E   +   S   S T P+   S      +          + P
Sbjct: 2252 GSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST-----TSRISP 2306

Query: 302  ADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPV---PPMEHELSIS 358
               E+T     T     S+A              S T   +P  P     P     L + 
Sbjct: 2307 GSTEITTLPGSTTTPGLSEA--------------STTFYSSPRSPTTTLSPASMTSLGVG 2352

Query: 359  EQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHL-ASPSVSV----- 412
            E+    +          SP    TPG   E   V  S PG  +T     +P+ SV     
Sbjct: 2353 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEP 2412

Query: 413  -----KPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL----- 462
                 +P     T+  E S   G +    E +T   GS     P + Q G P  L     
Sbjct: 2413 TTFHSRPASTHTTLFTEDSTTSGLT----EESTAFPGS-----PASTQTGLPATLTTADL 2463

Query: 463  -------PESSEEAGPL---AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
                   P SS   G     A    +        +  +PS T+       P T    E S
Sbjct: 2464 GEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS 2523

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPT 572
             T   +P ++P+                 AT+ P     +   E  +     P    T  
Sbjct: 2524 TTFYTSP-RSPD-----------------ATLSPATTTSSGVSEESSTSHSQPGSTHTTA 2565

Query: 573  QPPKKVVPQLRVYQGVTNPTPGQ-DQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
             P     P L  +   ++ +PG  D    P S +          T  P   +   HS+P 
Sbjct: 2566 FPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTT----------TSGPSQESTTSHSSPG 2615

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTE---VEPSTALMT 688
                         L    +  T HS        P     T+ P S T    VE ST + +
Sbjct: 2616 STDTALSPGSTTALSFGQESTTFHS-------SPGSTHTTLFPDSTTSSGIVEASTRVHS 2668

Query: 689  TAPPPGHPEVTL-PPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQ 747
            +    G P  TL P S          T     P     T  + P+T   P   +      
Sbjct: 2669 ST---GSPRTTLSPASSTSPGLQGESTTFQTHPASTH-TTPSPPSTATAPVEESTTYHRS 2724

Query: 748  PPDLGLAIIPEPTTETGHSTALEKTTA--PRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
            P        P  +T +GHS   EK+T     PD   T   S    T    E   ++ S  
Sbjct: 2725 PGSTPTTHFPASSTTSGHS---EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2781

Query: 806  QSESYTQNKALTAPEEHKASTS 827
             +E  T   + T P   +AST+
Sbjct: 2782 STEITTLPGSTTTPGLSEASTT 2803



 Score = 52.4 bits (124), Expect = 4e-06
 Identities = 132/623 (21%), Positives = 192/623 (30%), Gaps = 110/623 (17%)

Query: 257  MQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNET 316
            + QE+ A          TL     +    G +   +H       P   E T+   P N T
Sbjct: 1743 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHS-----SPGSTETTLL--PDNTT 1795

Query: 317  ESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSI-------SEQQQPVQPSES 369
             S   +  TP      V  S       + P         S        S+   P  P+ +
Sbjct: 1796 ASGLLEASTP------VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTT 1849

Query: 370  PREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEV 429
               VE S T   +P   P              T H ++ S ++   +   T+ + P A  
Sbjct: 1850 SAFVELSTTSHGSPSSTP--------------TTHFSASSTTLGRSEESTTVHSSPVATA 1895

Query: 430  GTSLVHQEATTRLSGSGNDVEPPAIQHGGPPL-----LPESSEEAGPLAVQQETSFQSPE 484
             T    +  T+ L      VE     H  P        PESS  +G  + +  TS  S  
Sbjct: 1896 TTPSPARSTTSGL------VEESTAYHSSPGSTQTMHFPESSTASGR-SEESRTSHSSTT 1948

Query: 485  PINNENPSPTQQEAAAEHPQT--AEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQA 542
               +  PS T   A  E P +  +  G ++ TH         FP+               
Sbjct: 1949 HTISSPPSTTS--ALVEEPTSYHSSPGSTATTH---------FPDSSTTSGRSEESTASH 1997

Query: 543  TVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQ--- 599
            + Q       +   S T V L     E+ T P      +     G T  TPG  +     
Sbjct: 1998 SSQDATGTIVLPARSTTSVLLG----ESTTSPISSGSMETTALPGSTT-TPGLSEKSTTF 2052

Query: 600  --HPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQ--H 655
               P SP+ T         ++P  TT  G S     +   P     T   PD   T    
Sbjct: 2053 HSSPRSPATT---------LSPASTTSSGVSEESTTSHSRPGSTHTTA-FPDSTTTPGLS 2102

Query: 656  SHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPP------------- 702
             H T +   P     T+ P S T   PS    T+   PG  +  L P             
Sbjct: 2103 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQEST 2162

Query: 703  ---SDKGQAQHSHLTQATVQPLDLELTI-----TTKPTTEVKPSPTT------EETSTQP 748
               S  G    +    +T     +E +      T  P T + P+ +T      E T+ Q 
Sbjct: 2163 TFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQT 2222

Query: 749  PDLGLAIIPEPTTETGHSTALEKTTAPR-PDRVQTLHRSLTEVTGPPTELEPAQDSLVQS 807
                    P P + T  +   E TT  R P    T H   +  T   +E      S   +
Sbjct: 2223 HPASTHTTPSPPS-TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 2281

Query: 808  ESYTQNKALTAPEEHKASTSTNI 830
               T + A +       ST++ I
Sbjct: 2282 SGTTPSSAHSTTSGRGESTTSRI 2304



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 155/742 (20%), Positives = 233/742 (31%), Gaps = 119/742 (16%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGS-----LPPELRVK--SDEPPGPSEQVGPSQFHLEPET 224
            +P +   +  +E SST    PGS      P        S EP       G ++  L P +
Sbjct: 3012 SPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGS 3071

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLT---------- 274
                +L   QS++           LL ++  +      + P  SS  SL           
Sbjct: 3072 TTASSLGQ-QSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTS 3130

Query: 275  --LPNHEVSVQP-PGEDQAYYHLPNITVKPADVEVTITSEPTN---------ETESSQAQ 322
              L     + Q  P         P  T  P +V  T  S P++          T   +++
Sbjct: 3131 AGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSE 3190

Query: 323  QETPIQ----------FPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            + T +           FP     S    E    P         ++         SE    
Sbjct: 3191 ESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTT 3250

Query: 373  VESSPTQQETPGQPPE------HHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPS 426
              SSP   +T   P          E T S      TH  A P  S   P V     A  S
Sbjct: 3251 FYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPG-STTMPGVSQESTASHS 3309

Query: 427  AEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGP-----PLLPESSEEAGPLAVQQETSFQ 481
            +   T       +T  S  G +       H GP      LLP+++  +G L        +
Sbjct: 3310 SPGSTDTTLSPGSTTASSLGPE---STTFHSGPGSTETTLLPDNTTASGLL--------E 3358

Query: 482  SPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQ---TPEFPNVVVA------- 531
            +  P+++   SP    + A    T  +GES+ T Q  P     TP  P    A       
Sbjct: 3359 ASTPVHSSTGSPHTTLSPAG--STTRQGEST-TFQSWPNSKDTTPAPPTTTSAFVELSTT 3415

Query: 532  --QPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVT 589
                P  +  T  +     LG +   E  T V  SP    T   P +     L       
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRS---EESTTVHSSPVATATTPSPARSTTSGLVEESTTY 3472

Query: 590  NPTPGQDQAQH-PVSPSV-------TVQLLDLGLTITPEPTTEVG--------HSTP--- 630
            + +PG  Q  H P S +        T        TI+  P+T           HS+P   
Sbjct: 3473 HSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST 3532

Query: 631  -----PKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTA 685
                 P  +  S +  E T  H  Q  T    L   +   + LG + T    +    +TA
Sbjct: 3533 ATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTA 3592

Query: 686  LMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETS 745
            L  +   PG        S+K    HS        P     T++   TT    S  +  + 
Sbjct: 3593 LPGSTTTPG-------LSEKSTTFHS-------SPRSPATTLSPASTTSSGVSEESTTSH 3638

Query: 746  TQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLV 805
            ++P        P+ TT  G S     + +       TL  + T  +G   E   +  S  
Sbjct: 3639 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSG 3698

Query: 806  QSESYTQNKALTAPEEHKASTS 827
             +++     + TA    + ST+
Sbjct: 3699 STDTALSPGSTTALSFGQESTT 3720



 Score = 49.3 bits (116), Expect = 3e-05
 Identities = 138/698 (19%), Positives = 226/698 (32%), Gaps = 93/698 (13%)

Query: 172  TPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQV-------GPSQFHLEPET 224
            +P S   +  +E S+T    PGS+       S   PG S++        G +   L P +
Sbjct: 4346 SPASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGS 4405

Query: 225  QNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQP 284
                +L    ++        +   L +   +S   EA      S+    T  +   S   
Sbjct: 4406 TTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTR 4465

Query: 285  PGEDQAYYHLPNI--------TVKPADVEVTITSE--PTNETESSQAQQETPIQFPEEVE 334
             GE   +   PN         T   A VE++ TS   P++   +  +   T +   EE  
Sbjct: 4466 QGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST 4525

Query: 335  PSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTV 394
               +   A    P P       + E+      S    +    P    T G+  E      
Sbjct: 4526 TVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGEE------ 4579

Query: 395  SPPGHHQTHHLASPSVSVKPPDVQLTIAAEP----SAEVGTSLVHQEATTRLSGSGND-- 448
            S   H  T H  S +     P     +  EP    S+   T+  H   ++  SG   +  
Sbjct: 4580 STTSHSSTTHTISSA-----PSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 4634

Query: 449  VEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEE 508
                +    G  +LP  S  +  L  +  TS     PI++ +   T    +   P  +E+
Sbjct: 4635 ASHSSQDATGTIVLPARSTTSVLLG-ESTTS-----PISSGSMETTALPGSTTTPGLSEK 4688

Query: 509  GESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTMK 568
               S T   +P+ TP                T  +     LG +   E  T V  SP   
Sbjct: 4689 ---STTFHSSPSSTPT---------------THFSASSTTLGRS---EESTTVHSSPVAT 4727

Query: 569  ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH-PVSPSVTVQLLDLGLTITPEPTTEVGH 627
             T   P +     L       + +PG  Q  H P S + + +  +   + T   +T    
Sbjct: 4728 ATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEE---SRTSHSSTTHTI 4784

Query: 628  STPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALM 687
            S+PP  T    + P      P  + T H              F  +  +    E STA  
Sbjct: 4785 SSPPSTTSALVEEPTSYHSSPGSIATTH--------------FPESSTTSGRSEESTA-- 4828

Query: 688  TTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTE-VKPSPTTEETST 746
            + + P  +    LP       + +  T   + P  +E T+ +  TT  +    T   +S+
Sbjct: 4829 SHSSPDTNGITPLPAHFTTSGRIAESTTFYISPGSMETTLASTATTPGLSAKSTILYSSS 4888

Query: 747  QPPDLGL--------AIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELE 798
            + PD  L        +I  EPT+    + +   T  P       L +  T     P   E
Sbjct: 4889 RSPDQTLSPASMTSSSISGEPTSLYSQAESTHTTAFPASTTTSGLSQESTTFHSKPGSTE 4948

Query: 799  PA-QDSLVQSESYTQNKALTAPEEHKASTSTNICELCT 835
                   + + S+ Q    T P     S  + +    T
Sbjct: 4949 TTLSPGSITTSSFAQE--FTTPHSQPGSALSTVSPAST 4984



 Score = 37.7 bits (86), Expect = 0.092
 Identities = 142/656 (21%), Positives = 202/656 (30%), Gaps = 96/656 (14%)

Query: 171  STPQSQKQTLQN--EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPE 228
            +TP   + T     E S+T    PGS       +S+   G  E         E  T +  
Sbjct: 4536 TTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESNTTSGRGE---------ESTTSHSS 4586

Query: 229  TLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGED 288
            T   I S      AP+    L+EE  S                S T    E S       
Sbjct: 4587 TTHTISS------APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQ 4640

Query: 289  QAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQ----FPEEVEPSATQQEAPI 344
             A      I +        +  E T    SS + + T +      P   E S T   +P 
Sbjct: 4641 DA---TGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPS 4697

Query: 345  EPPVPPMEHE---LSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ 401
              P          L  SE+   V  S        SP +  T G   E      S PG  Q
Sbjct: 4698 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLV-EESTAYHSSPGSTQ 4756

Query: 402  THHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGND----VEPPAIQHG 457
            T H    S            A+  S E  TS  H   T  +S   +     VE P   H 
Sbjct: 4757 TMHFPESST-----------ASGRSEESRTS--HSSTTHTISSPPSTTSALVEEPTSYHS 4803

Query: 458  GPPLL-----PESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
             P  +     PESS  +G    ++ T+  S    N   P P     +    ++     S 
Sbjct: 4804 SPGSIATTHFPESSTTSG--RSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYISP 4861

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS--HLTQATVQPLDLGFTITPESKTEVELSPTMKET 570
             + +   A T   P +       +S       T+ P  +  +      T +        T
Sbjct: 4862 GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHT 4921

Query: 571  PTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSP-SVTVQLLDLGLT------------I 617
               P       L       +  PG  +    +SP S+T        T            +
Sbjct: 4922 TAFPASTTTSGLSQESTTFHSKPGSTETT--LSPGSITTSSFAQEFTTPHSQPGSALSTV 4979

Query: 618  TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSM 677
            +P  TT  G S        SP   E T        + HS   ++T  P   GFT T    
Sbjct: 4980 SPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSIHSQ--QSTPFPDSPGFTHT---- 5033

Query: 678  TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELT---ITTKPTT- 733
              V P+T   T                +  A HS        PL    T   +  +PTT 
Sbjct: 5034 --VLPATLTTTDI------------GQESTAFHSSSDATGTTPLPARSTASDLVGEPTTF 5079

Query: 734  EVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTE 789
             + PSPT   T+  P     + + E +T T H++    +T    + ++TL   L +
Sbjct: 5080 YISPSPT--YTTLFPASSSTSGLTEEST-TFHTSPSFTSTIVSTESLETLAPGLCQ 5132


>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
          Length = 1012

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 128/525 (24%), Positives = 173/525 (32%), Gaps = 89/525 (16%)

Query: 175 SQKQTLQNEYSSTDTPYPGS-LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233
           S K+T   E S  ++P  G     + R  +DE     + +        P   +P+  E  
Sbjct: 111 SSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 170

Query: 234 QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
             SS QQ       Q+L+ +P ++Q      P  SS              PPG  Q    
Sbjct: 171 SDSSAQQ-------QMLQAQPPALQAPTGVTPAPSSA-------------PPGTPQ---- 206

Query: 294 LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP-IEPPVPPME 352
           LP     P+   V     PT    +SQA  +   Q P    P    Q+AP + P  PP  
Sbjct: 207 LPTPGPTPSATAVPPQGSPT----ASQAPNQP--QAPTAPVPHTHIQQAPALHPQRPPSP 260

Query: 353 HELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ------THHLA 406
           H         P+QP        S+P+      QPP H +    PPG H         H  
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSH----AQPPLHGQ---GPPGPHSLQAGPLLQHPG 313

Query: 407 SPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQEATTRLSGSGNDVE-------------P 451
            P     PP      A++  A +GTS    +   + +L  S + ++             P
Sbjct: 314 PPQPFGLPPQ-----ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 368

Query: 452 PAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPIN---NENPSPTQQ---EAAAEHPQT 505
            A+ H  PP      +   P A +       P P +   N  P P  +     +  HP +
Sbjct: 369 LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428

Query: 506 AEEGESSLTHQ-----EAPAQTPEFPNVVVAQPPEHSH----LTQATVQPLDLGFTITPE 556
           A      L  Q      +PAQ P         PP  SH    L Q   QP        P 
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488

Query: 557 SKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
               +   PT   T T P            G      G   A     P  TVQ+ +  L 
Sbjct: 489 GPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALD 545

Query: 617 ITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTR 660
              EP      S PP     SP+   V  P H  Q    + HL R
Sbjct: 546 DAEEP-----ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDR 585



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 133/624 (21%), Positives = 202/624 (32%), Gaps = 113/624 (18%)

Query: 180 LQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQ 239
           L  ++S       GS+      +  +P  P  +  P    +    +N  +     S+  +
Sbjct: 12  LSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSK 71

Query: 240 QEAPAQLPQLLEEEPSS------MQQEAPALPPESS---------MESLTLPNH------ 278
            E   +  + ++EE SS       Q+E  A   E +          + ++ PN       
Sbjct: 72  AETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEG 131

Query: 279 EVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQF--PEEVEPS 336
           E S      D+      +I         +I S   NE++S  + Q+  +Q   P    P+
Sbjct: 132 ESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 191

Query: 337 ATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSP 396
                    PP  P       +     V P  SP     +P Q + P  P  H  +  +P
Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 397 PGHHQ---THHLASPSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND---- 448
             H Q   + H   P  S  PP   LT  A +PSA          A   L G G      
Sbjct: 251 ALHPQRPPSPH-PPPHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHS 302

Query: 449 -VEPPAIQHGGPP----LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEA 498
               P +QH GPP    L P++S+   PL     A    TS Q P        +   Q+ 
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQP 358

Query: 499 AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPES 557
             E P        ++ H + P  TP  P +   Q  +H  HL+  +   ++      P  
Sbjct: 359 PREQP--LPPAPLAMPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPAL 415

Query: 558 KTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTI 617
           K    LS     +   PP +++PQ +         PG  Q+Q+                +
Sbjct: 416 KPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------L 459

Query: 618 TPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSM 677
            P P      S PP                        + L +   QP        P   
Sbjct: 460 PPPPA-----SHPP------------------------TGLHQVAPQPPFAQHPFVPGGP 490

Query: 678 TEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKP 737
             + P T   T+ PP G      PP     A    +   +  PL         PT ++K 
Sbjct: 491 PPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKE 541

Query: 738 SPTTE-ETSTQPPDLGLAIIPEPT 760
               + E    PP    +  PEPT
Sbjct: 542 EALDDAEEPESPPPPPRSPSPEPT 565



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 106/499 (21%), Positives = 157/499 (31%), Gaps = 82/499 (16%)

Query: 79  ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLS 138
           +DP D D    S S  +P+P    +++        DS+ +  +   Q  A Q       +
Sbjct: 145 SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 196

Query: 139 PQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
           P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 197 PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 255

Query: 199 LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                  PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 256 RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 314

Query: 246 LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
            PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 315 -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 373

Query: 297 ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
           I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 374 IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 419

Query: 357 ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                 P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 420 SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 470

Query: 417 VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
           +       P A                      + P +  G PP+ P +           
Sbjct: 471 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 508

Query: 477 ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
            TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 509 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 568

Query: 533 PPEHSHLTQATVQPLDLGF 551
            P H+  +    + LD G+
Sbjct: 569 TPSHASQSARFYKHLDRGY 587



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308 ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
           +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 82  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 141

Query: 365 QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
           + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 194

Query: 425 PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
           P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 195 PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 250

Query: 485 PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
            ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 251 ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 295

Query: 545 QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                     P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 296 ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 346

Query: 601 PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
           P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 347 PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 399

Query: 661 ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
            +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 400 PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 450

Query: 721 LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
             L  +    P     P     + + QPP      +P                 P P   
Sbjct: 451 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 495

Query: 781 QTLHRSLTEVTGPPTELEP 799
            T   + T   GP T  +P
Sbjct: 496 PTCPSTSTPPAGPGTSAQP 514



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 87/355 (24%), Positives = 119/355 (33%), Gaps = 72/355 (20%)

Query: 46  PLQLTSNPLGPPEPWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
           PLQ  +   G P   S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 271 PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 326

Query: 105 NLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER----LPVSPKKLKKDPAQRWSL 160
              P L T   A   P    Q  ASQ  L+ +  P+E+     P++   +K  P      
Sbjct: 327 GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP--- 381

Query: 161 AEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHL 220
                 I QL  PQ+ K                  PP L              GPS F +
Sbjct: 382 ------IPQLPAPQAHKH-----------------PPHLS-------------GPSPFSM 405

Query: 221 EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN--- 277
                 P  L+ + S S      A  P L     S     +PA PP    +S  LP    
Sbjct: 406 NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPA 464

Query: 278 -------HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP 330
                  H+V+ QPP     +   P +   P      IT      T +  A   T  Q P
Sbjct: 465 SHPPTGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPP 515

Query: 331 -EEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
                 S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 516 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 570


>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 128/525 (24%), Positives = 173/525 (32%), Gaps = 89/525 (16%)

Query: 175  SQKQTLQNEYSSTDTPYPGS-LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233
            S K+T   E S  ++P  G     + R  +DE     + +        P   +P+  E  
Sbjct: 665  SSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 724

Query: 234  QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
              SS QQ       Q+L+ +P ++Q      P  SS              PPG  Q    
Sbjct: 725  SDSSAQQ-------QMLQAQPPALQAPTGVTPAPSSA-------------PPGTPQ---- 760

Query: 294  LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP-IEPPVPPME 352
            LP     P+   V     PT    +SQA  +   Q P    P    Q+AP + P  PP  
Sbjct: 761  LPTPGPTPSATAVPPQGSPT----ASQAPNQP--QAPTAPVPHTHIQQAPALHPQRPPSP 814

Query: 353  HELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ------THHLA 406
            H         P+QP        S+P+      QPP H +    PPG H         H  
Sbjct: 815  HPPPHPSPHPPLQPLTGSAGQPSAPSH----AQPPLHGQ---GPPGPHSLQAGPLLQHPG 867

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQEATTRLSGSGNDVE-------------P 451
             P     PP      A++  A +GTS    +   + +L  S + ++             P
Sbjct: 868  PPQPFGLPPQ-----ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922

Query: 452  PAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPIN---NENPSPTQQ---EAAAEHPQT 505
             A+ H  PP      +   P A +       P P +   N  P P  +     +  HP +
Sbjct: 923  LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982

Query: 506  AEEGESSLTHQ-----EAPAQTPEFPNVVVAQPPEHSH----LTQATVQPLDLGFTITPE 556
            A      L  Q      +PAQ P         PP  SH    L Q   QP        P 
Sbjct: 983  AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042

Query: 557  SKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
                +   PT   T T P            G      G   A     P  TVQ+ +  L 
Sbjct: 1043 GPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALD 1099

Query: 617  ITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTR 660
               EP      S PP     SP+   V  P H  Q    + HL R
Sbjct: 1100 DAEEP-----ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDR 1139



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 145/670 (21%), Positives = 222/670 (33%), Gaps = 123/670 (18%)

Query: 118  ELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGIIRQLSTPQSQ 176
            E P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 106/499 (21%), Positives = 157/499 (31%), Gaps = 82/499 (16%)

Query: 79   ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLS 138
            +DP D D    S S  +P+P    +++        DS+ +  +   Q  A Q       +
Sbjct: 699  SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 750

Query: 139  PQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
            P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 809

Query: 199  LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                   PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 810  RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 868

Query: 246  LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
             PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 869  -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
            I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 928  IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 973

Query: 357  ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                  P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 974  SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 1024

Query: 417  VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
            +       P A                      + P +  G PP+ P +           
Sbjct: 1025 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 1062

Query: 477  ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
             TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 1122

Query: 533  PPEHSHLTQATVQPLDLGF 551
             P H+  +    + LD G+
Sbjct: 1123 TPSHASQSARFYKHLDRGY 1141



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 87/355 (24%), Positives = 119/355 (33%), Gaps = 72/355 (20%)

Query: 46   PLQLTSNPLGPPEPWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
            PLQ  +   G P   S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 880

Query: 105  NLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER----LPVSPKKLKKDPAQRWSL 160
               P L T   A   P    Q  ASQ  L+ +  P+E+     P++   +K  P      
Sbjct: 881  GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP--- 935

Query: 161  AEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHL 220
                  I QL  PQ+ K                  PP L              GPS F +
Sbjct: 936  ------IPQLPAPQAHKH-----------------PPHLS-------------GPSPFSM 959

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN--- 277
                  P  L+ + S S      A  P L     S     +PA PP    +S  LP    
Sbjct: 960  NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPA 1018

Query: 278  -------HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP 330
                   H+V+ QPP     +   P +   P      IT      T +  A   T  Q P
Sbjct: 1019 SHPPTGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPP 1069

Query: 331  -EEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
                  S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 128/598 (21%), Positives = 196/598 (32%), Gaps = 113/598 (18%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTE------TGHSTAL 769
            +L        + +P  E  + P+P        PP   +  +P P         +G S   
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 770  EKTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                 P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
          Length = 1566

 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 128/525 (24%), Positives = 173/525 (32%), Gaps = 89/525 (16%)

Query: 175  SQKQTLQNEYSSTDTPYPGS-LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDI 233
            S K+T   E S  ++P  G     + R  +DE     + +        P   +P+  E  
Sbjct: 665  SSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESD 724

Query: 234  QSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYH 293
              SS QQ       Q+L+ +P ++Q      P  SS              PPG  Q    
Sbjct: 725  SDSSAQQ-------QMLQAQPPALQAPTGVTPAPSSA-------------PPGTPQ---- 760

Query: 294  LPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP-IEPPVPPME 352
            LP     P+   V     PT    +SQA  +   Q P    P    Q+AP + P  PP  
Sbjct: 761  LPTPGPTPSATAVPPQGSPT----ASQAPNQP--QAPTAPVPHTHIQQAPALHPQRPPSP 814

Query: 353  HELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ------THHLA 406
            H         P+QP        S+P+      QPP H +    PPG H         H  
Sbjct: 815  HPPPHPSPHPPLQPLTGSAGQPSAPSH----AQPPLHGQ---GPPGPHSLQAGPLLQHPG 867

Query: 407  SPSVSVKPPDVQLTIAAEPSAEVGTS--LVHQEATTRLSGSGNDVE-------------P 451
             P     PP      A++  A +GTS    +   + +L  S + ++             P
Sbjct: 868  PPQPFGLPPQ-----ASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP 922

Query: 452  PAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPIN---NENPSPTQQ---EAAAEHPQT 505
             A+ H  PP      +   P A +       P P +   N  P P  +     +  HP +
Sbjct: 923  LAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982

Query: 506  AEEGESSLTHQ-----EAPAQTPEFPNVVVAQPPEHSH----LTQATVQPLDLGFTITPE 556
            A      L  Q      +PAQ P         PP  SH    L Q   QP        P 
Sbjct: 983  AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042

Query: 557  SKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLT 616
                +   PT   T T P            G      G   A     P  TVQ+ +  L 
Sbjct: 1043 GPPPI-TPPTCPSTSTPPAGPGTSAQPPCSGAA--ASGGSIAGGSSCPLPTVQIKEEALD 1099

Query: 617  ITPEPTTEVGHSTPPKRTIVSPKHPEVTLP-HPDQVQTQHSHLTR 660
               EP      S PP     SP+   V  P H  Q    + HL R
Sbjct: 1100 DAEEP-----ESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDR 1139



 Score = 64.3 bits (155), Expect = 9e-10
 Identities = 145/670 (21%), Positives = 222/670 (33%), Gaps = 123/670 (18%)

Query: 118  ELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEI-IGIIRQLSTPQSQ 176
            E P++P  F+        K   +E   +S K   +    R S++ +  G  +Q ++P  +
Sbjct: 546  EKPVDPPPFMF-------KPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGR 598

Query: 177  KQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSS 236
               +  +  S+    P +        +      +E V  S   ++ E  +P     ++S+
Sbjct: 599  TSPINEDIRSSGRNSPSA------ASTSSNDSKAETVKKSAKKVKEEASSP-----LKSN 647

Query: 237  SLQQEAPA----QLPQLLEEEPSSMQQEAPALPPESSMESLTLP--NHEVSVQPPGEDQA 290
              Q+E  A    +  +   ++  + +   P  P E   ES      N E S  P   DQ 
Sbjct: 648  KRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQD 707

Query: 291  YYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPP 350
                      P D E        ++++SS  QQ    Q P    P+         PP  P
Sbjct: 708  NRSTSPSIPSPQDNE--------SDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTP 759

Query: 351  MEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQ---THHLAS 407
                   +     V P  SP     +P Q + P  P  H  +  +P  H Q   + H   
Sbjct: 760  QLPTPGPTPSATAVPPQGSPT-ASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH-PP 817

Query: 408  PSVSVKPPDVQLT-IAAEPSAEVGTSLVHQEATTRLSGSGND-----VEPPAIQHGGPP- 460
            P  S  PP   LT  A +PSA          A   L G G          P +QH GPP 
Sbjct: 818  PHPSPHPPLQPLTGSAGQPSAP-------SHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQ 870

Query: 461  ---LLPESSEEAGPL-----AVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESS 512
               L P++S+   PL     A    TS Q P        +   Q+   E P        +
Sbjct: 871  PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPA----SQSALQSQQPPREQP--LPPAPLA 924

Query: 513  LTHQEAPAQTPEFPNVVVAQPPEHS-HLTQATVQPLDLGFTITPESKTEVELSPTMKETP 571
            + H + P  TP  P +   Q  +H  HL+  +   ++      P  K    LS     + 
Sbjct: 925  MPHIKPPPTTP-IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSA 983

Query: 572  TQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPP 631
              PP +++PQ +         PG  Q+Q+                + P P      S PP
Sbjct: 984  HPPPLQLMPQSQPLPSSPAQPPGLTQSQN----------------LPPPPA-----SHPP 1022

Query: 632  KRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAP 691
                                    + L +   QP        P     + P T   T+ P
Sbjct: 1023 ------------------------TGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTP 1058

Query: 692  PPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTE-ETSTQPPD 750
            P G      PP     A    +   +  PL         PT ++K     + E    PP 
Sbjct: 1059 PAGPGTSAQPPCSGAAASGGSIAGGSSCPL---------PTVQIKEEALDDAEEPESPPP 1109

Query: 751  LGLAIIPEPT 760
               +  PEPT
Sbjct: 1110 PPRSPSPEPT 1119



 Score = 51.2 bits (121), Expect = 8e-06
 Identities = 106/499 (21%), Positives = 157/499 (31%), Gaps = 82/499 (16%)

Query: 79   ADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLS 138
            +DP D D    S S  +P+P    +++        DS+ +  +   Q  A Q       +
Sbjct: 699  SDPKDIDQDNRSTSPSIPSPQDNESDS--------DSSAQQQMLQAQPPALQAPTGVTPA 750

Query: 139  PQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPE 198
            P    P +P+     P    +     G       P +Q Q        T      +L P+
Sbjct: 751  PSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAP-NQPQAPTAPVPHTHIQQAPALHPQ 809

Query: 199  LRVKSDEPPGPS-------------EQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQ 245
                   PP PS             +   PS        Q P     +Q+  L Q     
Sbjct: 810  RPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGP- 868

Query: 246  LPQLLEEEPSSMQQEAP------ALPPESSMESLTLPNHEVSVQPPGED---QAYYHLPN 296
             PQ     P + Q +AP      A  P +S++     +   S QPP E     A   +P+
Sbjct: 869  -PQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPH 927

Query: 297  ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
            I   P        + P  +  + QA +      P    PS     A + P  PP    LS
Sbjct: 928  IKPPP--------TTPIPQLPAPQAHKHP----PHLSGPSPFSMNANLPP--PPALKPLS 973

Query: 357  ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
                  P  PS  P  ++  P  Q  P  P +       PPG  Q+ +L  P  S  P  
Sbjct: 974  SLSTHHP--PSAHPPPLQLMPQSQPLPSSPAQ-------PPGLTQSQNLPPPPASHPPTG 1024

Query: 417  VQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQ 476
            +       P A                      + P +  G PP+ P +           
Sbjct: 1025 LHQVAPQPPFA----------------------QHPFVPGGPPPITPPTCPSTSTPPAGP 1062

Query: 477  ETSFQSPEPINNENPSPTQQEAAAEHP--QTAEEGESSLTHQEAPAQTPEFPN--VVVAQ 532
             TS Q P      +       ++   P  Q  EE        E+P   P  P+    V  
Sbjct: 1063 GTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVD 1122

Query: 533  PPEHSHLTQATVQPLDLGF 551
             P H+  +    + LD G+
Sbjct: 1123 TPSHASQSARFYKHLDRGY 1141



 Score = 46.2 bits (108), Expect = 3e-04
 Identities = 96/499 (19%), Positives = 153/499 (30%), Gaps = 73/499 (14%)

Query: 308  ITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAP--IEPPVPPMEHELSISEQQQPV- 364
            +  E ++  +S++ Q+E      EE + +++++     I  P  P E E   S+ +    
Sbjct: 636  VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695

Query: 365  QPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAE 424
            + S  P++++            P+ +E         Q        +  +PP +Q      
Sbjct: 696  EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQM-------LQAQPPALQAPTGVT 748

Query: 425  PSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPE 484
            P+         Q  T   + S   V P     G P      ++   P A    T  Q   
Sbjct: 749  PAPSSAPPGTPQLPTPGPTPSATAVPP----QGSPTASQAPNQPQAPTAPVPHTHIQQAP 804

Query: 485  PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATV 544
             ++ + P        + HP         L      A  P  P+   AQPP H        
Sbjct: 805  ALHPQRPP-------SPHPPPHPSPHPPLQPLTGSAGQPSAPSH--AQPPLHGQ------ 849

Query: 545  QPLDLGFTITPESKTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPG----QDQAQH 600
                      P     ++  P ++      P  + PQ    Q     +P         Q 
Sbjct: 850  ---------GPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQL 900

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTR 660
            P S S             P     + H  PP      P  P   LP P Q      HL+ 
Sbjct: 901  PASQSALQSQQPPREQPLPPAPLAMPHIKPP------PTTPIPQLPAP-QAHKHPPHLSG 953

Query: 661  ATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQP 720
             +  P  +   + P     ++P ++L T  PP  H     PP  +   Q   L  +  QP
Sbjct: 954  PS--PFSMNANLPPPPA--LKPLSSLSTHHPPSAH-----PPPLQLMPQSQPLPSSPAQP 1004

Query: 721  LDLELTITTKPTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRV 780
              L  +    P     P     + + QPP      +P                 P P   
Sbjct: 1005 PGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVP---------------GGPPPITP 1049

Query: 781  QTLHRSLTEVTGPPTELEP 799
             T   + T   GP T  +P
Sbjct: 1050 PTCPSTSTPPAGPGTSAQP 1068



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 87/355 (24%), Positives = 119/355 (33%), Gaps = 72/355 (20%)

Query: 46   PLQLTSNPLGPPEPWSSHSSHFPRESPHAP-TLPADPWDFDHLGPSASSEMPAPPQESTE 104
            PLQ  +   G P   S        + P  P +L A P    H GP     +P  PQ S +
Sbjct: 825  PLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPL-LQHPGPPQPFGLP--PQAS-Q 880

Query: 105  NLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQER----LPVSPKKLKKDPAQRWSL 160
               P L T   A   P    Q  ASQ  L+ +  P+E+     P++   +K  P      
Sbjct: 881  GQAP-LGT-SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTP--- 935

Query: 161  AEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHL 220
                  I QL  PQ+ K                  PP L              GPS F +
Sbjct: 936  ------IPQLPAPQAHKH-----------------PPHLS-------------GPSPFSM 959

Query: 221  EPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPN--- 277
                  P  L+ + S S      A  P L     S     +PA PP    +S  LP    
Sbjct: 960  NANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPP-GLTQSQNLPPPPA 1018

Query: 278  -------HEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFP 330
                   H+V+ QPP     +   P +   P      IT      T +  A   T  Q P
Sbjct: 1019 SHPPTGLHQVAPQPP-----FAQHPFVPGGPP----PITPPTCPSTSTPPAGPGTSAQPP 1069

Query: 331  -EEVEPSATQQEAPIEPPVPPME-HELSISEQQQPVQPSESPREVESSPTQQETP 383
                  S          P+P ++  E ++ + ++P  P   PR     PT  +TP
Sbjct: 1070 CSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTP 1124



 Score = 34.3 bits (77), Expect = 1.0
 Identities = 128/598 (21%), Positives = 196/598 (32%), Gaps = 113/598 (18%)

Query: 313  TNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPRE 372
            T E  SS+A +    Q       + T       P  PP    L +S        S S  +
Sbjct: 441  TPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLS--------SASEDD 492

Query: 373  VESSPTQQETPGQPPEHHEVTVSPPGHH-----------------QTHHLASPSVSVKPP 415
             +S  ++QE  G    H   T S   HH                 +   L      V PP
Sbjct: 493  FDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPP 552

Query: 416  DVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDV-----EPPAIQHGGPPLLPESSEEAG 470
                    E   + G S  H   T R  GS + +     + PA   G    + E    +G
Sbjct: 553  PFMFKPVKE--EDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSG 610

Query: 471  ---PLAV-------QQETSFQSPEPINNENPSP-----TQQEAAAEHPQTAEEGESSLTH 515
               P A        + ET  +S + +  E  SP      Q+E  A   + A+   S  T 
Sbjct: 611  RNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTK 670

Query: 516  QEAPAQTPEFPNVVVAQPPEHSHLT-QATVQPLDL---------GFTITPESKTEVELSP 565
             +  ++ P  P+    +  +   +  + +  P D+               +++++ + S 
Sbjct: 671  TQEISR-PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSA 729

Query: 566  TMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHP-VSPSVTVQLLDLGLTIT------ 618
              +    QPP    P   V    ++  PG  Q   P  +PS T        T +      
Sbjct: 730  QQQMLQAQPPALQAP-TGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQP 788

Query: 619  PEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
              PT  V H+   +   + P+ P    PHP    + H  L     QPL  G    P + +
Sbjct: 789  QAPTAPVPHTHIQQAPALHPQRP--PSPHPPPHPSPHPPL-----QPL-TGSAGQPSAPS 840

Query: 679  EVEPSTALMTTAPP-------------PGHPE-VTLPP-SDKGQAQHSHLTQATVQPLDL 723
              +P   L    PP             PG P+   LPP + +GQA       A      L
Sbjct: 841  HAQP--PLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSL 898

Query: 724  ELTI------TTKPTTE--VKPSPTTEETSTQPPDLGLAIIPEPTTE------TGHSTAL 769
            +L        + +P  E  + P+P        PP   +  +P P         +G S   
Sbjct: 899  QLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFS 958

Query: 770  EKTTAPRPDRVQTLHRSLT----EVTGPPTEL----EPAQDSLVQSESYTQNKALTAP 819
                 P P  ++ L    T        PP +L    +P   S  Q    TQ++ L  P
Sbjct: 959  MNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPP 1016


>gi|16554449 zonadhesin isoform 3 [Homo sapiens]
          Length = 2812

 Score = 72.0 bits (175), Expect = 4e-12
 Identities = 122/502 (24%), Positives = 181/502 (36%), Gaps = 75/502 (14%)

Query: 304  VEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQP 363
            V  T  SE T  TE+     + P    E+   +  +   P E P  P E     +E  +P
Sbjct: 548  VSSTGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTISTE--KP 605

Query: 364  VQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAA 423
              PSE P      PT    P + P       + P    T     P++S + P V      
Sbjct: 606  TIPSEKPNMPSEKPT---IPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPT 662

Query: 424  EPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSP 483
             P+ E  TS+  +E            E P+I    P   P  S E   ++ ++ T     
Sbjct: 663  TPTEETTTSM--EEPVIPTEKPSIPTEKPSI----PTEKPTISMEETIISTEKPTISPEK 716

Query: 484  EPINNENPS-PTQQEA-AAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQ 541
              I  E P+ PT++   + E P T  E  +  T  E P  +PE P     +P        
Sbjct: 717  PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPT--EKPTISPEKPTTPTEKP-------- 766

Query: 542  ATVQPLDLGFTITPESKTEVELSPTM-KETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQH 600
                      TI+PE  T     PT+  E PT P +K  P +   +     TP ++    
Sbjct: 767  ----------TISPEKLTIPTEKPTIPTEKPTIPTEK--PTISTEEPT---TPTEETTIS 811

Query: 601  PVSPSVTVQLLDLGLTITPEPTTEVGHST--------PPKRTIVSPKHPEVTLP------ 646
               PS+ ++   L    T E TT V  +T        P ++  +S + P  T+P      
Sbjct: 812  TEKPSIPMEKPTLP---TEETTTSVEETTISTEKLTIPMEKPTISTEKP--TIPTEKPTI 866

Query: 647  HPDQVQTQHSHLTRATVQP--------LDLGFTITPKSMTEVEPSTALMTTAPPPGHPEV 698
             P+++      LT  T +P        +       P     + P    ++T  P    E 
Sbjct: 867  SPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEK 926

Query: 699  TLPPSDKGQAQHSHLTQATVQPL--DLELTI-TTKPTTEVKPSPTTEETSTQPPDLGLAI 755
               P+++       LT  T +P     +LTI T KPT   +      E  T P +     
Sbjct: 927  PTIPTEETTISTEKLTIPTEKPTISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIP 986

Query: 756  IPEPTTETGHSTALEKTTAPRP 777
              +PT  T      EK TA RP
Sbjct: 987  TEKPTIPT------EKLTALRP 1002



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 125/557 (22%), Positives = 203/557 (36%), Gaps = 89/557 (15%)

Query: 135  DKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQNEYSSTDTPYPGS 194
            +K S     P  PK+    P ++ +++       +  T  S+K  + +E  +  +  P  
Sbjct: 575  EKPSVTTEKPTVPKEKPTIPTEKPTIST------EKPTIPSEKPNMPSEKPTIPSEKPTI 628

Query: 195  LPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEA-PAQLPQLLEEE 253
            L  +  + S++P  PSE+   S       T+ P T  +  ++S+++   P + P +  E+
Sbjct: 629  LTEKPTIPSEKPTIPSEKPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEK 688

Query: 254  PSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPT 313
            PS      P   P  SME   +   + ++ P          P I           T +PT
Sbjct: 689  PS-----IPTEKPTISMEETIISTEKPTISP--------EKPTIP----------TEKPT 725

Query: 314  NETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESPREV 373
              TE S    E P    E  +P+   ++  I P  P    E      ++   P+E P   
Sbjct: 726  IPTEKSTISPEKPTTPTE--KPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKP--- 780

Query: 374  ESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSL 433
             + PT  E P  P E   ++   P    T      ++S + P + +     P+ E  TS+
Sbjct: 781  -TIPT--EKPTIPTEKPTISTEEP----TTPTEETTISTEKPSIPMEKPTLPTEETTTSV 833

Query: 434  VHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSP 493
              +E T         +E P I    P +      E   ++ ++ T       I  E P+ 
Sbjct: 834  --EETTISTEKLTIPMEKPTISTEKPTI----PTEKPTISPEKLTIPTEKLTIPTEKPTI 887

Query: 494  TQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGF-- 551
              +E      +     E      E P  + E P +   +P   +  T  + + L +    
Sbjct: 888  PIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEK 947

Query: 552  -TITPESKTEVELSPTMK-ETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQ 609
             TI+PE  T     PT+  E PT P +K          +T PT      + P  P     
Sbjct: 948  PTISPEKLTIPTEKPTISTEKPTIPTEK----------LTIPT------EKPTIP----- 986

Query: 610  LLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPH-PDQVQTQHSHLTRATVQPLDL 668
                    T +PT         K T + P HP  T       V + H+  T  T   + L
Sbjct: 987  --------TEKPTIPT-----EKLTALRPPHPSPTATGLAALVMSPHAPSTPMT--SVIL 1031

Query: 669  GFTITPKSMTEVEPSTA 685
            G T T +S TE  P  A
Sbjct: 1032 GTTTTSRSSTERCPPNA 1048



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 94/421 (22%), Positives = 160/421 (38%), Gaps = 51/421 (12%)

Query: 34  VKEAQPLEWVKDPLQLTSNPLGPPEP--WSSHSSHFPRESP-----------HAPTLPAD 80
           V + +P    + P   T  P  P E     S     P E P             PT+P++
Sbjct: 586 VPKEKPTIPTEKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSE 645

Query: 81  PWDFDHLGPSASSEMPAPPQEST-----ENLVPFLDTWDSAGELPLEPEQFLASQQDL-- 133
                   P+  +E P  P E T     E ++P         +  +  E+   S ++   
Sbjct: 646 KPTISTEKPTVPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETII 705

Query: 134 ---KDKLSPQERLPVSPKKLKKDPAQRWSLA-EIIGIIRQLSTPQSQKQTLQNEYSSTDT 189
              K  +SP++  P  P +    P ++ +++ E      +  T  ++K T+  E  +T T
Sbjct: 706 STEKPTISPEK--PTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTPT 763

Query: 190 PYPGSLPPELRVKSDEPPGPSEQ-----VGPSQFHLEPETQNPETLEDIQSSSLQQEAPA 244
             P   P +L + +++P  P+E+       P+    EP T   ET    +  S+  E P 
Sbjct: 764 EKPTISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTEETTISTEKPSIPMEKPT 823

Query: 245 QLPQLLEEEPSSMQQEA--------PALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPN 296
            LP   EE  +S+++          P   P  S E  T+P  + ++ P   ++       
Sbjct: 824 -LP--TEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISP---EKLTIPTEK 877

Query: 297 ITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELS 356
           +T+ P +       E T  TE      E P   PE+   S  +   P E P  P E E +
Sbjct: 878 LTI-PTEKPTIPIEETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTE-ETT 935

Query: 357 ISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPD 416
           IS ++  + P+E P     SP +   P + P       + P    T     P++  + P 
Sbjct: 936 ISTEKLTI-PTEKP---TISPEKLTIPTEKPTISTEKPTIPTEKLTIPTEKPTIPTEKPT 991

Query: 417 V 417
           +
Sbjct: 992 I 992



 Score = 62.0 bits (149), Expect = 5e-09
 Identities = 121/585 (20%), Positives = 197/585 (33%), Gaps = 110/585 (18%)

Query: 49   LTSNP-LGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLV 107
            LT NP +   +P  S     P  +   PT+P +        P+ S+E P  P E      
Sbjct: 559  LTENPTISTKKPTVSIEK--PSVTTEKPTVPKEKPTIPTEKPTISTEKPTIPSEK----- 611

Query: 108  PFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGII 167
                                                P  P +    P+++ +      I+
Sbjct: 612  ------------------------------------PNMPSEKPTIPSEKPT------IL 629

Query: 168  RQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNP 227
             +  T  S+K T+ +E  +  T  P        V ++EP  P+E+   S       T+ P
Sbjct: 630  TEKPTIPSEKPTIPSEKPTISTEKP-------TVPTEEPTTPTEETTTSMEEPVIPTEKP 682

Query: 228  ETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGE 287
                +  S   ++   +    ++  E  ++  E P +P E      T+P  + ++     
Sbjct: 683  SIPTEKPSIPTEKPTISMEETIISTEKPTISPEKPTIPTEKP----TIPTEKSTIS---- 734

Query: 288  DQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP 347
                   P     P +     T +PT   E      E P   PE++     +   P E P
Sbjct: 735  -------PEKPTTPTEKPTIPTEKPTISPEKPTTPTEKPTISPEKLTIPTEKPTIPTEKP 787

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEH-----HEVTVSPPGHHQT 402
              P E + +IS ++      E+    E      E P  P E       E T+S      T
Sbjct: 788  TIPTE-KPTISTEEPTTPTEETTISTEKPSIPMEKPTLPTEETTTSVEETTIST--EKLT 844

Query: 403  HHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLL 462
              +  P++S + P +      +P+       +  E  T         E P I       +
Sbjct: 845  IPMEKPTISTEKPTIP---TEKPTISPEKLTIPTEKLT------IPTEKPTIP------I 889

Query: 463  PESSEEAGPLAVQQETSFQSPE--PINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPA 520
             E++     L +  E    SPE   I+ E P+   ++      +T    E      E P 
Sbjct: 890  EETTISTEKLTIPTEKPTISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPT 949

Query: 521  QTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKTEVELSPTM-KETPTQPPKKVV 579
             +PE   +   +P      T +T +P     TI  E  T     PT+  E PT P +K+ 
Sbjct: 950  ISPEKLTIPTEKP------TISTEKP-----TIPTEKLTIPTEKPTIPTEKPTIPTEKLT 998

Query: 580  PQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTE 624
              LR        T        P +PS  +  + LG T T   +TE
Sbjct: 999  -ALRPPHPSPTATGLAALVMSPHAPSTPMTSVILGTTTTSRSSTE 1042



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 92/394 (23%), Positives = 145/394 (36%), Gaps = 72/394 (18%)

Query: 64   SSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELP-LE 122
            S+  P  SP  PT+P +         + S E P  P E      P + T     E P + 
Sbjct: 706  STEKPTISPEKPTIPTEKPTIPTEKSTISPEKPTTPTEK-----PTIPT-----EKPTIS 755

Query: 123  PEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIRQLSTPQSQKQTLQN 182
            PE+            +P E+  +SP+KL               I  +  T  ++K T+  
Sbjct: 756  PEK----------PTTPTEKPTISPEKLT--------------IPTEKPTIPTEKPTIPT 791

Query: 183  EYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQE- 241
            E  +  T  P +   E  + +++P  P E         +P     ET   ++ +++  E 
Sbjct: 792  EKPTISTEEPTTPTEETTISTEKPSIPME---------KPTLPTEETTTSVEETTISTEK 842

Query: 242  --APAQLPQLLEEEPSSMQQEAPALPPES---SMESLTLPNHEVSVQPPGEDQAYYHLPN 296
               P + P +  E+P ++  E P + PE      E LT+P  + ++       +   L  
Sbjct: 843  LTIPMEKPTISTEKP-TIPTEKPTISPEKLTIPTEKLTIPTEKPTIPIEETTISTEKLTI 901

Query: 297  ITVKPADVEVTITSE-PTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPP-------- 347
             T KP     TI+ E PT  TE      E P    EE   S  +   P E P        
Sbjct: 902  PTEKP-----TISPEKPTISTEKPTIPTEKPTIPTEETTISTEKLTIPTEKPTISPEKLT 956

Query: 348  VPPMEHELSISEQQQPVQPSESPREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLAS 407
            +P  +  +S  +   P +    P E  + PT  E P  P E       P        LA+
Sbjct: 957  IPTEKPTISTEKPTIPTEKLTIPTEKPTIPT--EKPTIPTEKLTALRPPHPSPTATGLAA 1014

Query: 408  PSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTR 441
              +S   P   +T     S  +GT+   + +T R
Sbjct: 1015 LVMSPHAPSTPMT-----SVILGTTTTSRSSTER 1043



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 91/398 (22%), Positives = 148/398 (37%), Gaps = 53/398 (13%)

Query: 459 PPLLPESSEEAGP---LAVQQETSFQSPEP-INNENPSPTQQEAAAEHPQTAEEGESSLT 514
           PP+ P SS   GP     + +  +  + +P ++ E PS T ++      +     E    
Sbjct: 543 PPVSPVSS--TGPSETTGLTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPTEKPTI 600

Query: 515 HQEAPAQTPEFPNVVVAQPPEHSHL-TQATVQPLDLGFTITPESKTEVELSPTMK-ETPT 572
             E P    E PN+   +P   S   T  T +P     TI  E  T     PT+  E PT
Sbjct: 601 STEKPTIPSEKPNMPSEKPTIPSEKPTILTEKP-----TIPSEKPTIPSEKPTISTEKPT 655

Query: 573 QPPKK-VVPQLRVYQGVTNPTPGQDQAQHPVS-PSVTVQLLDLGL----------TITPE 620
            P ++   P       +  P    ++   P   PS+  +   + +          TI+PE
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 621 -PTTEVGHST-PPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMT 678
            PT      T P +++ +SP+ P      P  + T+     + T+ P       TP    
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPT-IPTE-----KPTISPEK---PTTPTEKP 766

Query: 679 EVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITT--------K 730
            + P    + T  P    E    P++K        T  T      E TI+T        K
Sbjct: 767 TISPEKLTIPTEKPTIPTEKPTIPTEKPTISTEEPTTPTE-----ETTISTEKPSIPMEK 821

Query: 731 PTTEVKPSPTTEETSTQPPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEV 790
           PT   + + T+ E +T   +     + +PT  T   T   +     P+++      LT  
Sbjct: 822 PTLPTEETTTSVEETTISTEKLTIPMEKPTISTEKPTIPTEKPTISPEKLTIPTEKLTIP 881

Query: 791 TGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
           T  PT   P +++ + +E  T    K   +PE+   ST
Sbjct: 882 TEKPT--IPIEETTISTEKLTIPTEKPTISPEKPTIST 917



 Score = 31.2 bits (69), Expect = 8.6
 Identities = 73/340 (21%), Positives = 117/340 (34%), Gaps = 46/340 (13%)

Query: 520 AQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESKT-EVELSPTMKETPTQPPKKV 578
           +Q P + N  V  P  H        QP+ L F     S T  V     +   P   P KV
Sbjct: 486 SQRPYWQNTSVTVPSGHQ-------QPMQLIFKGIQGSNTASVVAMGFILINPGTCPVKV 538

Query: 579 VPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSP 638
           +P+L     V++  P +      ++ + T+      ++I     T    + P ++  +  
Sbjct: 539 LPELPPVSPVSSTGPSETTG---LTENPTISTKKPTVSIEKPSVTTEKPTVPKEKPTIPT 595

Query: 639 KHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPST------ALMTTAPP 692
           + P ++   P     + +  +     P +    +T K     E  T       + T  P 
Sbjct: 596 EKPTISTEKPTIPSEKPNMPSEKPTIPSEKPTILTEKPTIPSEKPTIPSEKPTISTEKPT 655

Query: 693 PGHPEVTLP-------------PSDKGQAQHSHLTQATVQP-LDLELTI--TTKPTTEVK 736
               E T P             P++K        +  T +P + +E TI  T KPT   +
Sbjct: 656 VPTEEPTTPTEETTTSMEEPVIPTEKPSIPTEKPSIPTEKPTISMEETIISTEKPTISPE 715

Query: 737 PSPTTEETSTQPPDLGLAIIPEPTTETGHST--------ALEKTTAPRPDRVQTLHRSLT 788
                 E  T P +       +PTT T   T        + EK T P  ++       LT
Sbjct: 716 KPTIPTEKPTIPTEKSTISPEKPTTPTEKPTIPTEKPTISPEKPTTP-TEKPTISPEKLT 774

Query: 789 EVTGPPTELEPAQDSLVQSESYT--QNKALTAPEEHKAST 826
             T  PT   P +   + +E  T    +  T  EE   ST
Sbjct: 775 IPTEKPT--IPTEKPTIPTEKPTISTEEPTTPTEETTIST 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.372 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,155,523
Number of Sequences: 37866
Number of extensions: 4416629
Number of successful extensions: 26371
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 209
Number of HSP's successfully gapped in prelim test: 1175
Number of HSP's that attempted gapping in prelim test: 16442
Number of HSP's gapped (non-prelim): 6372
length of query: 1635
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1519
effective length of database: 13,855,062
effective search space: 21045839178
effective search space used: 21045839178
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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