Guide to the Human Genome
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Search of human proteins with 239508959

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]
         (528 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo ...  1070   0.0  
gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo ...  1070   0.0  
gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]          1070   0.0  
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa...    54   5e-07
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap...    52   1e-06
gi|239752594 PREDICTED: hypothetical protein, partial [Homo sapi...    52   2e-06
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa...    52   2e-06
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa...    52   2e-06
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap...    52   2e-06
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap...    52   2e-06
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   3e-06
gi|163965366 nascent polypeptide-associated complex alpha subuni...    50   4e-06
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                49   1e-05
gi|23510413 sorting nexin 26 [Homo sapiens]                            48   2e-05
gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo sapi...    48   3e-05
gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]     47   4e-05
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    47   6e-05
gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]                 47   6e-05
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]                 47   6e-05
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    46   7e-05
gi|169210256 PREDICTED: hypothetical protein [Homo sapiens]            46   7e-05
gi|116734706 interferon regulatory factor 2 binding protein 2 is...    46   7e-05
gi|116734704 interferon regulatory factor 2 binding protein 2 is...    46   7e-05
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]                 46   1e-04
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    45   1e-04
gi|182507165 thymus expressed gene 3-like [Homo sapiens]               45   2e-04
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]         45   2e-04
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         45   2e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    44   3e-04

>gi|239749196 PREDICTED: hypothetical protein XP_002346951 [Homo
           sapiens]
          Length = 528

 Score = 1070 bits (2766), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60
           MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA
Sbjct: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60

Query: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120
           KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE
Sbjct: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120

Query: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180
           REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA
Sbjct: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180

Query: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240
           DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE
Sbjct: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240

Query: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300
           PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR
Sbjct: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300

Query: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360
           GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG
Sbjct: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360

Query: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420
           ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA
Sbjct: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420

Query: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480
           AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG
Sbjct: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480

Query: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528
           SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY
Sbjct: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528


>gi|239743276 PREDICTED: hypothetical protein XP_002342815 [Homo
           sapiens]
          Length = 528

 Score = 1070 bits (2766), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60
           MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA
Sbjct: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60

Query: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120
           KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE
Sbjct: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120

Query: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180
           REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA
Sbjct: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180

Query: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240
           DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE
Sbjct: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240

Query: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300
           PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR
Sbjct: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300

Query: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360
           GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG
Sbjct: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360

Query: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420
           ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA
Sbjct: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420

Query: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480
           AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG
Sbjct: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480

Query: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528
           SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY
Sbjct: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528


>gi|239508959 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 528

 Score = 1070 bits (2766), Expect = 0.0
 Identities = 528/528 (100%), Positives = 528/528 (100%)

Query: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60
           MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA
Sbjct: 1   MSSAGVSSSSFNKGDFAAPVELLPPVEPHVVTEDVEGELGASTLWAVAFYPRGLEELWVA 60

Query: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120
           KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE
Sbjct: 61  KLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQE 120

Query: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180
           REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA
Sbjct: 121 REGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELA 180

Query: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240
           DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE
Sbjct: 181 DFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGE 240

Query: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300
           PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR
Sbjct: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300

Query: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360
           GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG
Sbjct: 301 GGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGG 360

Query: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420
           ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA
Sbjct: 361 ARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFLQGTADETHQSLA 420

Query: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480
           AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG
Sbjct: 421 AAFRHRHLGAESGAVSSTNAVAALSLAWCWAQTEITYPTLHLGLVTPRGSSLQALHKGSG 480

Query: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528
           SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY
Sbjct: 481 SHQGPGYLGEGKEEVSQPREQAIEYEGVLGIQAAVGVGEELGQRVLGY 528


>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
           sapiens]
          Length = 2715

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 52/187 (27%), Positives = 73/187 (39%), Gaps = 32/187 (17%)

Query: 241 PPTTGGKLTGPARLRSSRAPPPARRPLPCESLR-----TPSGTAGPRSPASGPDARGAPT 295
           PP        PA+     +PPP   P  C   R     TPS  A   +  +GP+    PT
Sbjct: 438 PPPLPSPPPPPAQEEQEESPPPVV-PATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496

Query: 296 PGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRC-----RLVPAAVVGRSSSVT--- 347
           P            TP+T  G GPP     V P+++       + +   V  RSS V    
Sbjct: 497 P------------TPSTATG-GPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTP 543

Query: 348 ---IDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLR 404
              +D   P   +   +  LR     S  +P   +  P PSPPRA  PP +P+ L    R
Sbjct: 544 RRFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPA--PVPSPPRAPTPPSTPVPLPEKRR 601

Query: 405 TVFLQGT 411
           ++  + T
Sbjct: 602 SILREPT 608



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 48/206 (23%), Positives = 64/206 (31%), Gaps = 38/206 (18%)

Query: 126 GTGKGEVTERWSQGQEEGQRQLE--------TAVQLRKALVGDRGVIPQACSQSWLSLP- 176
           G  +G V E  S   E  + + +            LR AL   RG  P+   +   + P 
Sbjct: 102 GPSRGCVPEEESSDGESDEEEFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPL 161

Query: 177 --PELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLL 234
             P LAD       +PA                         R+ G  G E    +   L
Sbjct: 162 PPPRLADVAPTPPKTPA-------------------------RKRGEEGTERMVQALTEL 196

Query: 235 TCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAP 294
              A  P     +   P+  R SR  PP R   PC   +     A        P+     
Sbjct: 197 LRRAQAPQAPRSRACEPSTPRRSRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPPPV 256

Query: 295 TPGRARGGGASWSATPTTIPGPGPPR 320
            P + + G  SW       PGPG PR
Sbjct: 257 VPVKHQTG--SWKCKEGPGPGPGTPR 280



 Score = 36.2 bits (82), Expect = 0.076
 Identities = 46/173 (26%), Positives = 64/173 (36%), Gaps = 20/173 (11%)

Query: 223  GPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR 282
            G E   L + +L   A E  +    L  P R  S  APPPA R      ++ P+ +   R
Sbjct: 1816 GGEDPPLDTDVLVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPS-R 1874

Query: 283  SPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSR--CRLVPAAVV 340
             P  G      P+P    G  +S +    T+  P  P P     PR SR    L P    
Sbjct: 1875 RPLGGVSFGPLPSP----GSPSSLTHHIPTVGDPDFPAP-----PRRSRRPSPLAPRPPP 1925

Query: 341  GRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
             R +S  +  S           R+   T V + +  T+     P P  + PPP
Sbjct: 1926 SRWASPPLKTSPQL--------RVPPPTSVVTALTPTSGELAPPGPAPSPPPP 1970



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 66/271 (24%), Positives = 85/271 (31%), Gaps = 65/271 (23%)

Query: 165 PQACSQSWLSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGP 224
           P A  +   S PP +   C  +R  P   PS+            A R  +R    GTS P
Sbjct: 447 PPAQEEQEESPPPVVPATCSRKRGRPPLTPSQR-----------AEREAARAGPEGTSPP 495

Query: 225 EASTLSSGLLTCSAGEP---PTTGGKLTGPAR-----------LRSSRAPPPARR----- 265
             +       T + G P   PT   K T   +            RSSR     RR     
Sbjct: 496 TPTPS-----TATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDED 550

Query: 266 -PLPCES-----LRTPSGTAGP--RSPASGPDARGAPTPGRA------------RGGGAS 305
            P P +      LR P  T+ P  + PA  P    APTP               R     
Sbjct: 551 PPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFR 610

Query: 306 WSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLR 365
           W++    +P P P  P     P        PA    R   +      P+ +       L+
Sbjct: 611 WTSLTRELPPPPPAPPP----PPAPSPPPAPATSSRRPLLLRAPQFTPSEAH------LK 660

Query: 366 AGTGVSSQIPYTASLTPTPSPPRASPPPFSP 396
               V +  P  A   P P PP A   P  P
Sbjct: 661 IYESVLTPPPLGAPEAPEPEPPPADDSPAEP 691


>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
          Length = 2161

 Score = 52.0 bits (123), Expect = 1e-06
 Identities = 90/368 (24%), Positives = 129/368 (35%), Gaps = 42/368 (11%)

Query: 48   AFYPRGLEELWVAKLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPP 107
            +F P G   +   K +   E + +P L P A+K ++  + PG   +    +    P  PP
Sbjct: 876  SFLPPGPGLMLRQKSIGAAEDD-RPYLAPPAMKFSRSLSVPGSEDIPPPPTTS--PPEPP 932

Query: 108  GSEVPRAAASWQ----EREGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGV 163
             S  P  ++S +     R GP   G G      S    +G    +T V  R+  +   G 
Sbjct: 933  YSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPPDTRVGSREKSLYHSGP 992

Query: 164  IPQACSQS----WLSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRV 219
            +P A            PP            P    +   P      LA+  +   R  R 
Sbjct: 993  LPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPPPRLALGPQPSLRGWRG 1052

Query: 220  GTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTA 279
            G   P     S      + G     GG   GPA LR  + PP A         R+  G  
Sbjct: 1053 GGPSPTPGAPSPSHHGSAGGG----GGSSQGPA-LRYFQLPPRAASAAMYVPARSGRGRK 1107

Query: 280  GPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAV 339
            GP    +     G P     +GGG   + +PT+   P PP    +  P       +P  +
Sbjct: 1108 GPLVKQT--KVEGEPQ----KGGGLPPAPSPTSPASPQPP--PAVAAPSEKNSIPIPTII 1159

Query: 340  V--------GRSSSVTIDHSRPASS---RGGGARRLRAGTGVSSQIPYTASLTPTPSPPR 388
            +        GRSS  +   + P +     GGG      G G SS  P  A ++P P  P 
Sbjct: 1160 IKAPSTSSSGRSSQGSSTEAEPPTQPEPTGGG------GGGGSSPSPAPA-MSPVPPSPS 1212

Query: 389  ASPPPFSP 396
              P P SP
Sbjct: 1213 PVPTPASP 1220



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 74/294 (25%), Positives = 103/294 (35%), Gaps = 48/294 (16%)

Query: 94   QEHQSLPGLPEPP--PGSEVPRAAASWQEREGPCGTGKGEVTERWSQGQEEGQRQLETAV 151
            Q   + PG P PP  P    P  AA     + P GT  G + E  S+   +   +  ++ 
Sbjct: 1636 QGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTDSG-IEEVDSRSSSDHPLETISSA 1694

Query: 152  QLRKALVGDRGVIPQACSQSWLSLP--PELADFCLC----QRVSPASCPSRSCPSAAVFI 205
                +L  + G        +   +   PEL D  +     Q    +S P    P   +  
Sbjct: 1695 STLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYLDGQAFGGSSTPGPPYPPQLM-- 1752

Query: 206  LAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPT---TGGKLTGPARLRSSRAPPP 262
                  S  R R +G SG      S GL        PT   TG    G   LR+   PP 
Sbjct: 1753 ----TPSKLRGRALGASGGLRPGPSGGLRDPVTPTSPTVSVTGAGTDGLLALRACSGPPT 1808

Query: 263  ARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTI----PGPGP 318
            A             G AG    A  P+    P P        + S+ P  +     GPGP
Sbjct: 1809 A-------------GVAGG-PVAVEPEVPPVPLP--------TASSLPRKLLPWEEGPGP 1846

Query: 319  PRPQL---LVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTG 369
            P P L   L  P+ S    V A+++   SS  +     +S+ GG     R G+G
Sbjct: 1847 PPPPLPGPLAQPQASALATVKASIISELSS-KLQQFGGSSAAGGALPWARGGSG 1899



 Score = 33.1 bits (74), Expect = 0.64
 Identities = 54/202 (26%), Positives = 72/202 (35%), Gaps = 45/202 (22%)

Query: 173 LSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSG 232
           L++PP L        +   S  S + P   VF    AA S       G  GP +   S G
Sbjct: 428 LTVPPAL--------LRANSDTSMALPDWMVFSAPGAASS-------GAPGPTSG--SQG 470

Query: 233 LLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARG 292
               SA     + G L   +  R +RA  P+R   P ++ R P G          P + G
Sbjct: 471 QSQPSAPTTKLSSGTLRSASSPRGARARSPSRGRHPEDAKRQPRGR---------PSSSG 521

Query: 293 APTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSR 352
            P  G A G G S         GPG        +    R R + +AV GRS      +  
Sbjct: 522 TPREGPAGGTGGS--------GGPGGS------LGSRGRRRKLYSAVPGRSFMAVKSYQA 567

Query: 353 PAS-----SRGGGARRLRAGTG 369
            A      S+G   + L  G G
Sbjct: 568 QAEGEISLSKGEKIKVLSIGEG 589


>gi|239752594 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 673

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 64/262 (24%), Positives = 98/262 (37%), Gaps = 52/262 (19%)

Query: 161 RGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVG 220
           R  + +  S S L+  P +A     +R+ P +  +R+ P A++      A          
Sbjct: 73  RASLTRMQSSSLLTRTPSMASL---KRMPPRASRTRTLPRASLMRRPSTASL-------- 121

Query: 221 TSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPA---RRPLPCESLRTPSG 277
           T  P  ++L++     S    P+T   LT P+R   +R PP A     P      RTP  
Sbjct: 122 TRSPSRASLTTTPSRASLSMTPSTAAALTMPSRASLTRTPPRASLTMTPSTASLTRTP-- 179

Query: 278 TAGPRSPASGPDARGAPTP----------------GRARGGGASWSATPTTIPGPGPPRP 321
              PR+  +G  +R +PT                  R     +     P   P   PPR 
Sbjct: 180 ---PRASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTPPRASPTGSPPRA 236

Query: 322 QLLVIPRTSRC-----RLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPY 376
            L ++P T+       R  P  ++ R+S   +D +   +         R  T   +  P 
Sbjct: 237 SLSMMPSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPS-----RPSTASPTGTPS 291

Query: 377 TASLTPTPSP-------PRASP 391
            ASL+ TPS        PRASP
Sbjct: 292 RASLSMTPSTASLMRMLPRASP 313



 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 60/225 (26%), Positives = 82/225 (36%), Gaps = 34/225 (15%)

Query: 187 RVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGG 246
           R SP   P R+ P+             SR    GT    + T S    T S    P+T  
Sbjct: 436 RASPTGTPPRASPTGTP----------SRASPTGTQSTASPTGSPS--TASPTGSPSTAS 483

Query: 247 KLTGPARLRSSRAPPPA---RRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGG 303
               P+R   +R P  A   +        RTPS  A P    S     G+P+   A G  
Sbjct: 484 PTGSPSRASLTRTPSRASLTKMESTASITRTPS-RASPTWTPSTASPTGSPSTALAMGSP 542

Query: 304 ASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARR 363
           +  + T T      P R  L   P  +       A + R+ S  +    P S+   G   
Sbjct: 543 SRAALTRT------PSRASLTRTPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPS 596

Query: 364 LRAGTGVSS-----QIPYTASLT-------PTPSPPRASPPPFSP 396
             + TG+ S     ++  TAS+T       PT +PPRASP    P
Sbjct: 597 RTSPTGMPSSALLTKMDSTASITRTPPRASPTETPPRASPTGTPP 641



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 69/234 (29%), Positives = 89/234 (38%), Gaps = 49/234 (20%)

Query: 187 RVSPASCPSRSCPSAAVFILAVA--------ARSCSRRRRVGTSGPEASTLSSGLLTCSA 238
           R SP   PSR+ P+      ++          R+ SR    GT  P AS           
Sbjct: 181 RASPTGMPSRTSPTGMPSTASLTKMDSTASITRTLSRASPTGTP-PRASP---------T 230

Query: 239 GEPPTTGGKLTGPARLRSSRAPPPARRP--LPCESLRTPSGTAG-PRSPASGPDARGAPT 295
           G PP     +  P+     R PP A     L   SL     TA   R+P+    A    T
Sbjct: 231 GSPPRASLSMM-PSTALLIRTPPRASPTGMLSRTSLTKMDSTASITRTPSRPSTASPTGT 289

Query: 296 PGRARGGGASWSATPTT------IPGPGPP----RPQLLVIPRT-SRCRLVPAAVVGRSS 344
           P RA     S S TP+T      +P   P     R  L  +  T S  R  P A + R+ 
Sbjct: 290 PSRA-----SLSMTPSTASLMRMLPRASPTGMLSRTSLTKMDSTASISRTPPRASITRTP 344

Query: 345 SVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLT-------PTPSPPRASP 391
           S      +P+++   G     + TG     P TASLT       PT +PPRASP
Sbjct: 345 SRASPTGKPSTASPTGTPSRASPTGS----PSTASLTGLSSTASPTGTPPRASP 394



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 61/229 (26%), Positives = 91/229 (39%), Gaps = 40/229 (17%)

Query: 189 SPASCPSRSCPSAAVFILAVAARSCSRR------RRVGTSGPEASTLS--------SGLL 234
           SP   PSR+ P+ +    ++   S +        R   T  P  ++L+        +G+L
Sbjct: 357 SPTGTPSRASPTGSPSTASLTGLSSTASPTGTPPRASPTGTPSTASLTRKPPRASPTGML 416

Query: 235 T-CSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGA 293
           +  S  +  +T      P R   +  PP A  P    S  +P+GT    SP   P +  +
Sbjct: 417 SRTSITKMDSTASPTRTPPRASPTGTPPRAS-PTGTPSRASPTGTQSTASPTGSP-STAS 474

Query: 294 PTPGRARGGGASWSATPTTIPGPGPPRPQLLVIP-RTSRCRLVPAAVVGRSSSVTIDHSR 352
           PT       G+  +A+PT      P R  L   P R S  ++   A + R+ S       
Sbjct: 475 PT-------GSPSTASPT----GSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWT 523

Query: 353 P--ASSRGGGARRLRAGT---GVSSQIPYTASLTPTPS------PPRAS 390
           P  AS  G  +  L  G+      ++ P  ASLT TPS      P RAS
Sbjct: 524 PSTASPTGSPSTALAMGSPSRAALTRTPSRASLTRTPSRASLTTPSRAS 572



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 68/244 (27%), Positives = 91/244 (37%), Gaps = 51/244 (20%)

Query: 257 SRAPPPA---RRPLPCESLRTPSGTAGPRSPASGPDARGAPT--PGRARGGGASWSATPT 311
           SR PP A   R P    S  +P+G     SP   P +R +PT  P  A   G S +A+PT
Sbjct: 332 SRTPPRASITRTP----SRASPTGKPSTASPTGTP-SRASPTGSPSTASLTGLSSTASPT 386

Query: 312 TIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVS 371
             P            PR        A+  G  S+ ++    P +S  G   R       +
Sbjct: 387 GTP------------PR--------ASPTGTPSTASLTRKPPRASPTGMLSR-------T 419

Query: 372 SQIPYTASLTPTPSPPRAS----PPPFSPLYLGGHLRTVFLQGTADET-HQSLAAAFRHR 426
           S     ++ +PT +PPRAS    PP  SP            Q TA  T   S A+     
Sbjct: 420 SITKMDSTASPTRTPPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSP 479

Query: 427 HLGAESGA---VSSTNAVAALSLAWCWAQTEIT------YPTLHLGLVTPRGSSLQALHK 477
              + +G+    S T   +  SL    +   IT       PT      +P GS   AL  
Sbjct: 480 STASPTGSPSRASLTRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAM 539

Query: 478 GSGS 481
           GS S
Sbjct: 540 GSPS 543



 Score = 38.9 bits (89), Expect = 0.012
 Identities = 59/234 (25%), Positives = 95/234 (40%), Gaps = 22/234 (9%)

Query: 176 PPELADFCLCQRVSPASCPSRSCPSAAVFILA------VAARSCSRRRRVGTSGPEASTL 229
           PP  +      R SP   PSR+ P+      +       A+ + S      T  P  ++L
Sbjct: 434 PPRASPTGTPPRASPTGTPSRASPTGTQSTASPTGSPSTASPTGSPSTASPTGSPSRASL 493

Query: 230 SSGLLTCSAGEPPTTGGKLTGPARLRSSRAPP---PARRPLPCESLRTPSGTAGPRSPAS 286
           +      S  +  +T      P+R   +  P    P   P    ++ +PS  A  R+P+ 
Sbjct: 494 TRTPSRASLTKMESTASITRTPSRASPTWTPSTASPTGSPSTALAMGSPSRAALTRTPSR 553

Query: 287 GPDARGAPTPGRAR---GGGASWSATPTTIPGPG-PPRPQLLVIP-RTSRCRLVPAAVVG 341
               R   TP RA       AS + TP+T+     PP      +P RTS   +  +A++ 
Sbjct: 554 ASLTR---TPSRASLTTPSRASLTRTPSTVLLTRMPPSASPTGMPSRTSPTGMPSSALLT 610

Query: 342 R-SSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTAS---LTPTPSPPRASP 391
           +  S+ +I  + P +S      R  + TG   +   T +    +PT +PPRASP
Sbjct: 611 KMDSTASITRTPPRASPTETPPRA-SPTGTPPRASPTGTPPRASPTGTPPRASP 663


>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
           sapiens]
          Length = 817

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 209 AARSCSRRRRVGTSGPE--ASTLSSGL----LTCSAGEPPTTGGKLTGPARLRSSRAPPP 262
           A  S S+ +   TS P+  A T   GL    ++ ++G  P    K    A  R S  P  
Sbjct: 445 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK 504

Query: 263 ARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQ 322
             +P P    + P   A P  PAS P +R      +      + +A  +T P    P   
Sbjct: 505 DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTL 564

Query: 323 LLVIPRTSRCRLVPAAVVGRSS-SVTIDHSRPASSRGGGARRLRAGTG---VSSQIPYTA 378
           L   P   +    PA V   ++ SV  D SRP S+     ++    +G    +  +P   
Sbjct: 565 LPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV 624

Query: 379 SLTPTPSPPRASP 391
             TP PS P  +P
Sbjct: 625 KATPMPSRPSTTP 637


>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
           sapiens]
          Length = 1135

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 209 AARSCSRRRRVGTSGPE--ASTLSSGL----LTCSAGEPPTTGGKLTGPARLRSSRAPPP 262
           A  S S+ +   TS P+  A T   GL    ++ ++G  P    K    A  R S  P  
Sbjct: 710 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK 769

Query: 263 ARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQ 322
             +P P    + P   A P  PAS P +R      +      + +A  +T P    P   
Sbjct: 770 DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTL 829

Query: 323 LLVIPRTSRCRLVPAAVVGRSS-SVTIDHSRPASSRGGGARRLRAGTG---VSSQIPYTA 378
           L   P   +    PA V   ++ SV  D SRP S+     ++    +G    +  +P   
Sbjct: 830 LPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV 889

Query: 379 SLTPTPSPPRASP 391
             TP PS P  +P
Sbjct: 890 KATPMPSRPSTTP 902


>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
           sapiens]
          Length = 887

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 209 AARSCSRRRRVGTSGPE--ASTLSSGL----LTCSAGEPPTTGGKLTGPARLRSSRAPPP 262
           A  S S+ +   TS P+  A T   GL    ++ ++G  P    K    A  R S  P  
Sbjct: 445 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK 504

Query: 263 ARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQ 322
             +P P    + P   A P  PAS P +R      +      + +A  +T P    P   
Sbjct: 505 DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTL 564

Query: 323 LLVIPRTSRCRLVPAAVVGRSS-SVTIDHSRPASSRGGGARRLRAGTG---VSSQIPYTA 378
           L   P   +    PA V   ++ SV  D SRP S+     ++    +G    +  +P   
Sbjct: 565 LPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV 624

Query: 379 SLTPTPSPPRASP 391
             TP PS P  +P
Sbjct: 625 KATPMPSRPSTTP 637


>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo
           sapiens]
          Length = 1152

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 51/193 (26%), Positives = 75/193 (38%), Gaps = 10/193 (5%)

Query: 209 AARSCSRRRRVGTSGPE--ASTLSSGL----LTCSAGEPPTTGGKLTGPARLRSSRAPPP 262
           A  S S+ +   TS P+  A T   GL    ++ ++G  P    K    A  R S  P  
Sbjct: 710 AKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK 769

Query: 263 ARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQ 322
             +P P    + P   A P  PAS P +R      +      + +A  +T P    P   
Sbjct: 770 DVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTL 829

Query: 323 LLVIPRTSRCRLVPAAVVGRSS-SVTIDHSRPASSRGGGARRLRAGTG---VSSQIPYTA 378
           L   P   +    PA V   ++ SV  D SRP S+     ++    +G    +  +P   
Sbjct: 830 LPKKPTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRV 889

Query: 379 SLTPTPSPPRASP 391
             TP PS P  +P
Sbjct: 890 KATPMPSRPSTTP 902


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 61/213 (28%), Positives = 81/213 (38%), Gaps = 44/213 (20%)

Query: 217 RRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAP-PPARRPLPCESLRTP 275
           R   T  P+ S LS+G    ++G  P T      PA  R SRA       P P  S R  
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGT----PSPAMARRSRAAGTEVGLPRPAPSARPR 199

Query: 276 SGTAGPRSPASG----------PDARGAPTPG----RARGGGASWSATPTTIPG------ 315
             T GPR   S           P AR  P+ G    R      S SATP + P       
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259

Query: 316 ---------PGPPRP---QLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARR 363
                    P  P+P   Q L  P+ +  R   A  +G  SS  +    P+ ++   AR 
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK---ARP 316

Query: 364 LRAGTGVSSQIPYTASLTPTPSPPRASPPPFSP 396
           +      ++ +P T      PSPP A+P P +P
Sbjct: 317 VPPPDNAATPLPATLP----PSPPLATPLPLAP 345



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 52/181 (28%), Positives = 72/181 (39%), Gaps = 12/181 (6%)

Query: 220 GTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTA 279
           G   P A   S G ++       TT     G   LR S A     R    E+ +  + +A
Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-AEETVARGKATEAPKRSALSA 158

Query: 280 GPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPP-RPQLLVIPRTSRCRLVPAA 338
           G R   SGP   G P+P  AR   A+   T   +P P P  RP+    P T   R   ++
Sbjct: 159 GARRDTSGPTP-GTPSPAMARRSRAA--GTEVGLPRPAPSARPR----PPTEGPRKSVSS 211

Query: 339 VVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPS---PPRASPPPFS 395
               S++     +R   S GGG +R  + +  SS  P ++     PS    PRA   P  
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271

Query: 396 P 396
           P
Sbjct: 272 P 272



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 63/236 (26%), Positives = 86/236 (36%), Gaps = 42/236 (17%)

Query: 184 LCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTL-------SSGLLTC 236
           L    +P S P+RS PSA     A A  S  + + +    P   T        + G L+ 
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS 301

Query: 237 SAGEPPTTGGKLTGPARLRSSRAPP-PARRPLPCESLRTPSGTAGPRSPASGPDARGAPT 295
           S    P+  G    P     + A P PA  P P   L TP   A P SP++ P  +  P+
Sbjct: 302 SPLATPSPSGTKARPVPPPDNAATPLPATLP-PSPPLATPLPLAPP-SPSAPPSLQTLPS 359

Query: 296 PGRARGGGASWSATPTTIPGPGPPR---------PQLLVIPRTSRCRLVPAAVVGRS--- 343
           P             P T P   PP          P L  IP       VP ++   S   
Sbjct: 360 P-------------PATPPSQAPPSMTTPPMQAPPSLQTIPPIQ----VPHSLTSPSLQA 402

Query: 344 --SSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPL 397
             S + +   +  +S G    +        S     ASLT +PS P ++PP   PL
Sbjct: 403 PPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLT-SPSRPASTPPDSPPL 457



 Score = 37.7 bits (86), Expect = 0.026
 Identities = 50/185 (27%), Positives = 73/185 (39%), Gaps = 21/185 (11%)

Query: 242 PTTGGKLTGPARLRSSRAPPPARRPL--PCESLRTPSGTAGPRSPA--SGPDARGAPTPG 297
           P      T P++   S A PP + P   P     +PS T  P++P   + P  +  P+P 
Sbjct: 683 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPP 742

Query: 298 RARGGGASWSATPTTIPGPGPPR-PQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASS 356
                 AS   +P+  P   PPR P LL  P        PA++     +     + PA +
Sbjct: 743 ------ASPPMSPSATP---PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793

Query: 357 RGGGARRLRAGTGVSSQIPYTASLTPT---PSPPRASPPPFSPLYLGGHLRTVFLQGTAD 413
                  L+A     +  P  A  +P+   P  P A+PPP +P  L   L  V     A 
Sbjct: 794 ----TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPAS 849

Query: 414 ETHQS 418
            T Q+
Sbjct: 850 PTLQA 854



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 65/269 (24%), Positives = 92/269 (34%), Gaps = 21/269 (7%)

Query: 188 VSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTS-GPEASTLSSGLLTCSAGEPPTTGG 246
           +SP + PS   P+A    L  A  S      V     P AS   S   T  +  PP+   
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701

Query: 247 KL--------TGPARLRSSRAPPPARRPLPCESLRTPSG--TAGPRSPASGPDARGAP-- 294
                       P    S+  PP A  PL    L+ P     + P SP++ P  R  P  
Sbjct: 702 PPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLL 761

Query: 295 -TPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGR---SSSVTIDH 350
             P          S   + +  P P  P  L  P        PA+  G+   S S ++  
Sbjct: 762 AAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPM 821

Query: 351 SRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGGHLRTVFL-Q 409
           S  A+        L A      Q+P +   +PT   PR  P P     + G   T+ L  
Sbjct: 822 SPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAP 878

Query: 410 GTADETHQSLAAAFRHRHLGAESGAVSST 438
           G      +S ++      L   S + +ST
Sbjct: 879 GPPPPPSRSPSSTLSGPDLAGHSSSATST 907



 Score = 35.4 bits (80), Expect = 0.13
 Identities = 41/159 (25%), Positives = 53/159 (33%), Gaps = 22/159 (13%)

Query: 190 PASCPSRSCPSAAVFILAVAARSCSRRRRVG--TSGPEASTLSSGL--LTCSAGEPPTTG 245
           P   P +S  SA+       + +  RR   G     P + +LSS    L+  A   P+  
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260

Query: 246 GKLTGPAR-----------LRSSRAPPP------ARRPLPCESLRTPSGTAGPRSPASGP 288
           G    PA            LR  +  PP      A  PL    L TPS +     P   P
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPP 320

Query: 289 DARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIP 327
           D    P P          +  P   P P  P P L  +P
Sbjct: 321 DNAATPLPATLPPSPPLATPLPLAPPSPSAP-PSLQTLP 358



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 58/209 (27%), Positives = 71/209 (33%), Gaps = 22/209 (10%)

Query: 191  ASCPSRSCPSAAVFILAV-----AARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTG 245
            A+ P ++ P  A  +L V     A+ +    RR  T GP+ S     L    A  PP   
Sbjct: 825  ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP- 883

Query: 246  GKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRS-PASGPDARGAPTPGRARGGGA 304
                 P+R  SS    P        +  TP    G  S P  G  A   P    A    A
Sbjct: 884  -----PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 938

Query: 305  SWS---ATPTTIPG-PGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVT-----IDHSRPAS 355
            +WS   A P    G PG P P        S   L          S T     +D   P+ 
Sbjct: 939  AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG-PSP 997

Query: 356  SRGGGARRLRAGTGVSSQIPYTASLTPTP 384
               GG     AG G SS+ P  A L   P
Sbjct: 998  GTSGGKAAAGAGAGASSRSPKQARLGELP 1026



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 38/137 (27%), Positives = 51/137 (37%), Gaps = 7/137 (5%)

Query: 260 PPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGAS-WSATPTTIPGP-G 317
           P  A R  P  S  T S     R PASG   R  P    + G  +S   A+ TT PGP G
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 318 PPRPQLLVIPRTSRCRLVPA---AVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQI 374
               ++      +R +   A   + +   +        P +     ARR RA  G    +
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGL 189

Query: 375 PYTASLTPTPSPPRASP 391
           P  A  +  P PP   P
Sbjct: 190 PRPAP-SARPRPPTEGP 205



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 8/95 (8%)

Query: 221  TSGPEASTLSSGLLTCSAGEPPTTGGK-LTGPARLRSSRAPPPAR-RPLPCESLRTP--- 275
            T GPE++T + G L      P T+GGK   G     SSR+P  AR   LP  +L+     
Sbjct: 978  TEGPESATPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 1036

Query: 276  --SGTAGPRSPASGPDARGAPTPGRARGGGASWSA 308
                     + A G        PG A GGG +  A
Sbjct: 1037 HLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGA 1071



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 59/247 (23%), Positives = 89/247 (36%), Gaps = 37/247 (14%)

Query: 163 VIPQACSQSWLSLPPELADFCLCQRVSPASC---PSRSCPSAAVFILAVAARSCSRRRRV 219
           ++P   +QS L+ PP L       +  PAS    P  + PS A   L  A+   +     
Sbjct: 508 IMPPLETQSSLA-PPSL-------QTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLE 559

Query: 220 GTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTA 279
               P    L +     +   P T     T P +   + A PP +  LP   L +P  T 
Sbjct: 560 TPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQG-LPSPPL-SPLATP 617

Query: 280 GPRSPA--SGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRP---QLLVIPRTS---- 330
            P++P   + P  +  P+P       AS   +P   P P  P      LL  P +     
Sbjct: 618 PPQAPPXLALPPLQAPPSPP------ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSP 671

Query: 331 --RCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPR 388
             +    P A    S S T     P S      +       V    P +  ++P+ +PP 
Sbjct: 672 PVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQ-------VPPSPPASPPMSPSATPPP 724

Query: 389 ASPPPFS 395
            +PPP +
Sbjct: 725 QAPPPLA 731



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 38/146 (26%), Positives = 50/146 (34%), Gaps = 23/146 (15%)

Query: 190  PASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLT 249
            P+  PS +     +   + +A S     R   SGPE           +A  PP       
Sbjct: 884  PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--------AASPPPDAELAAC 935

Query: 250  GPARLRSSRAPPPARR-----PLP---------CESLRTPSGTAGPRSPASGPDARG-AP 294
             PA      APP A R     PLP          + L T   T GP S    P A    P
Sbjct: 936  HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 995

Query: 295  TPGRARGGGASWSATPTTIPGPGPPR 320
            +PG + G  A+ +    +   P   R
Sbjct: 996  SPGTSGGKAAAGAGAGASSRSPKQAR 1021


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 67/240 (27%), Positives = 87/240 (36%), Gaps = 51/240 (21%)

Query: 190  PASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLT 249
            PA+ P     S A   L   A +          G  A+    G  T  A  PP+  G   
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 250  GPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDA----------RGAPT---- 295
             P+  + +  PP A  P P   L TP     P +PA+ P +          +GAPT    
Sbjct: 1096 TPSP-KGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAA 1154

Query: 296  -PGRARGGGASW--SATPTTIPGPGPPRPQL-LVIPRTSRCRLVPAAVVGRSSSVTIDHS 351
             P   +GG A+      PTT P   PP P+  L  P        PAA             
Sbjct: 1155 TPPSPKGGLATPPPKGAPTT-PAATPPSPKGGLATPSPKGAPTTPAAT------------ 1201

Query: 352  RPASSRGG-------GARRLRAGT------GVSSQIPYTASLTPTPSPPR-----ASPPP 393
             P S +GG       GA    A T      G+++  P  A  TP  +PP      A+PPP
Sbjct: 1202 -PPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPP 1260



 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 54/189 (28%), Positives = 70/189 (37%), Gaps = 27/189 (14%)

Query: 223  GPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR 282
            G  A+    G  T  A  PP+  G L  P+  + +   P A  P P   L TPS    P 
Sbjct: 1161 GGLATPPPKGAPTTPAATPPSPKGGLATPSP-KGAPTTPAATPPSPKGGLATPSPKGAPT 1219

Query: 283  SPASGPDA----------RGAP-----TPGRARGGGASWSATPTTIPGPGPPRPQLLVIP 327
            +PA+ P +          +GAP     TP   +GG       P T P  G P P     P
Sbjct: 1220 TPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG-------PATPPPKGAPTPPAATPP 1272

Query: 328  RTSRCRLVPAAVVGRSSSVTIDHS---RPASSRGGGARRLRAGTGVSSQ-IPYTASLTPT 383
                    P      + +V    S    PA+S   GA    A T  S +  P T      
Sbjct: 1273 SLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGA 1332

Query: 384  PSPPRASPP 392
            P+PP  +PP
Sbjct: 1333 PTPPAVTPP 1341



 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 47/176 (26%), Positives = 69/176 (39%), Gaps = 25/176 (14%)

Query: 223  GPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR 282
            G  A++   G  T  A  PP+  G         S   PPP   P P  ++  PS    P 
Sbjct: 1299 GGPATSPPKGAPTPPAATPPSPKG---------SPGTPPPKGAPTP-PAVTPPSPKGTPT 1348

Query: 283  SPASGPDARGAPTPGRARGGGASWSATPTTIPGPG--PPRPQLLVIPRTSRCRLVPAAVV 340
             PA+ P ++G PT   ++ G    +ATP+   GP   PP P+        R   +P+   
Sbjct: 1349 LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPK--------RGPAIPSPKG 1400

Query: 341  GRSSSVTIDHS---RPAS--SRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASP 391
              +S   I  S    PA+  +R G A   +      +  P +    P  S P+  P
Sbjct: 1401 DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGP 1456



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 46/155 (29%), Positives = 61/155 (39%), Gaps = 20/155 (12%)

Query: 255  RSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDA-RGAPTPGRARGGGASWSATPTT- 312
            + +  PP A  P P     TPS    P  PA+ P + +G P     +G     +ATP + 
Sbjct: 937  KGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSP 996

Query: 313  -----IPGP-GPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGG------- 359
                  P P G P P  +  P        PAA      + T   + P S +G        
Sbjct: 997  KGGPATPSPKGAPTPPAVTPPSPKGS---PAATPFPKGASTPPAATPPSPKGSPAATPLP 1053

Query: 360  -GARRLRAGTGVSSQ-IPYTASLTPTPSPPRASPP 392
             GA    A T  S +  P T SL   P+PP A+PP
Sbjct: 1054 KGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPP 1088



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 65/241 (26%), Positives = 82/241 (34%), Gaps = 57/241 (23%)

Query: 189  SPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKL 248
            SP   P+   P  A    AV   S           P A+    G  T  A  PP+  G  
Sbjct: 995  SPKGGPATPSPKGAPTPPAVTPPSPK-------GSPAATPFPKGASTPPAATPPSPKGSP 1047

Query: 249  TGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDA----------RGAP---- 294
                  + +   P A  P P     TPS    P  PA+ P +          +GAP    
Sbjct: 1048 AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA 1107

Query: 295  -TPGRARGGGAS--WSATPTTIPGPGPPRPQ-LLVIPRTSRCRLVPAAVVGRSSSVTIDH 350
             TP   +GG A+      PTT P   PP P+  L  P        PAA            
Sbjct: 1108 ATPPSPKGGLATPPHKGAPTT-PAATPPSPKGGLATPPPKGAPTTPAAT----------- 1155

Query: 351  SRPASSRGG-------GARRLRAGT------GVSSQIPYTASLTPTPSPPR-----ASPP 392
              P S +GG       GA    A T      G+++  P  A  TP  +PP      A+P 
Sbjct: 1156 --PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1213

Query: 393  P 393
            P
Sbjct: 1214 P 1214



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 56/236 (23%), Positives = 82/236 (34%), Gaps = 27/236 (11%)

Query: 173 LSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGT--SGPEASTLS 230
           L L PE+        + PA  P  +     +   +  A   S  +   T  SG  A+  S
Sbjct: 724 LVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASS 783

Query: 231 SGLLTCSAGEPPTTGGKLTG----PARLRSSRAPPPARRPL-----PCESLRTPSGTAGP 281
            G LT  A  P   G  ++     P   + S  P      L     P E+   P  +   
Sbjct: 784 KGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSF 843

Query: 282 RSPASGPDARGAPTPGRARGGGASWSATP-----TTIPGPGPPRPQLLVIPRTSRCRLVP 336
           +     P    +PTP   +G     + TP      T+P    P P ++ +P        P
Sbjct: 844 QGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903

Query: 337 AAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPP 392
           A     + S+T   S P  +R          T     IP + S    P+PP A+PP
Sbjct: 904 APKQAPALSMT--SSSPKKARA---------TPAPKGIPASPSPKGAPTPPAATPP 948



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 77/339 (22%), Positives = 112/339 (33%), Gaps = 63/339 (18%)

Query: 64   AGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVP--------RAA 115
            + +EG   P   P       H+  P  M     +  P +P P      P        +A 
Sbjct: 1364 SSKEGPTPPAATP------SHKGGPA-MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAP 1416

Query: 116  ASWQEREGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSL 175
            A+   REG     KG++T               T V L+KA        P   +      
Sbjct: 1417 ATPVTREGAATPSKGDLTP-----------PAVTPVSLKKA--------PATSAPKGGPA 1457

Query: 176  PPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLT 235
             P          V+P S      P          A S S ++   T  P  +     ++ 
Sbjct: 1458 TPSSKGDPTLPAVTPPSPKEPPAPKQV-------ATSSSPKKAPATPAPMGAPTLPAVIP 1510

Query: 236  CSAGEPPTTGGKLTGP----ARLRSSRAPPPARRPLPCESLRTPSGTA-GPRSPASGPDA 290
             S  E P T      P    A L S + P       P E+L  P+ T   P+   + P  
Sbjct: 1511 SSPKEVPATPSSRRDPIAPTATLLSKKTPATLA---PKEALIPPAMTVPSPKKTPAIPTP 1567

Query: 291  RGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRS--SSVTI 348
            + AP    ++   +  + TP+T    G P P+ L         L+P AV   S   + T 
Sbjct: 1568 KEAPATPSSKEASSPPAVTPSTYK--GAPSPKEL---------LIPPAVTSPSPKEAPTP 1616

Query: 349  DHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPP 387
                P S   G A     GT  S  +   +SL  +P+ P
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTSPPVT-PSSLKDSPTSP 1654



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 41/154 (26%), Positives = 52/154 (33%), Gaps = 58/154 (37%)

Query: 240 EPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRA 299
           E P T      PA   +S +P  AR             T  P+   + P  +GAPTP   
Sbjct: 898 EGPATPAPKQAPALSMTSSSPKKAR------------ATPAPKGIPASPSPKGAPTP--- 942

Query: 300 RGGGASWSATPTTIP-GPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRG 358
                  +ATP +   GP  P P+    P        PAA              P S +G
Sbjct: 943 ------PAATPPSPKGGPATPSPKWAPTP--------PAAT-------------PPSPKG 975

Query: 359 GGARRLRAGTGVSSQIPYTASLTPTPSPPRASPP 392
           G               P T S    P+PP A+PP
Sbjct: 976 G---------------PATPSPKGAPTPPAATPP 994


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 48.5 bits (114), Expect = 1e-05
 Identities = 86/363 (23%), Positives = 126/363 (34%), Gaps = 86/363 (23%)

Query: 80  KQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQEREGPCGTGKGEVTERWSQG 139
           K   H ++ G M   +  + PGLP   PGS+VP+  +  Q  +G C           S+G
Sbjct: 17  KATAHNSSWGEM---QAPNAPGLPADVPGSDVPQGPSDSQILQGLCA----------SEG 63

Query: 140 QEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSCP 199
                                  V+P +       +PP +++       S AS       
Sbjct: 64  P-------------------STSVLPTSAEGPSTFVPPTISE------ASSASGQPTISE 98

Query: 200 SAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTC---------SAGEPPTTGGKLTG 250
                +L   +   S      TSGP   T+S GL T          +   PPT+  + + 
Sbjct: 99  GPGTSVLPTPSEGLS------TSGP--PTISKGLCTSVTLAASEGRNTSRPPTSSEEPST 150

Query: 251 PARLRSSRAPPPARRPLPCESLRT---PSGTAGPR-----SPASGPDARGAPTPGRARGG 302
                +S  P  +  P P E   T   P+   GP      +P  GP     PTPG   G 
Sbjct: 151 SVPPTASEVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGEGPGT 210

Query: 303 GASWSAT---PTTIPGPGPPRPQLLVIPRTSR---CRLVPAAVVGRSSSVTIDHSR---- 352
               +AT    T++       P   V P  +      + P    G S+SV          
Sbjct: 211 SVPLAATEGLSTSVQATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPST 270

Query: 353 ---PASSRGGGARRL-RAGTGVSSQIPYTA------SLTPTPSPPRASPPPFSPLYLGGH 402
              PA+S G     +   G G S+ +P TA      S+ PT     ++  P +P   GG 
Sbjct: 271 SVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTP---GGG 327

Query: 403 LRT 405
           L T
Sbjct: 328 LST 330



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 61/205 (29%), Positives = 75/205 (36%), Gaps = 43/205 (20%)

Query: 199 PSAAVFILAVAARSCSR--RRRVGTSGPEASTLSSGLLTC---SAGE------PPTTGGK 247
           PS +V   A   +S S    R  G+S     T + GL T    +AGE      PPT GG 
Sbjct: 268 PSTSVLPAASDGQSISLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGG 327

Query: 248 LTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWS 307
           L       S+  PP A   L          T+ P +P  GP     P PG     G S S
Sbjct: 328 L-------STSVPPTATEEL---------STSVPPTPGEGPSTSVLPIPGE----GLSTS 367

Query: 308 ATPTTIPGPGPPRPQLLVIPRTSRCRLV-PAAVVGRSSSVTIDHSRPASSRGGGARRLRA 366
             PT   G     P     P      LV P A  G  SSV         + G G   L +
Sbjct: 368 VPPTASDGSDTSVPP---TPGEGASTLVQPTAPDGPGSSV-------LPNPGEGPSTLFS 417

Query: 367 GTGVSSQIPYTASLT-PTPSPPRAS 390
            +    + P   SL  P+P   +AS
Sbjct: 418 SSASVDRNPSKCSLVLPSPRVTKAS 442


>gi|23510413 sorting nexin 26 [Homo sapiens]
          Length = 1126

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 55/177 (31%), Positives = 72/177 (40%), Gaps = 22/177 (12%)

Query: 237 SAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCES--------LRTPSGTAGPRSPASGP 288
           SAG  P     L  P  L  S    P+ R L  E         L TP+    P++PAS  
Sbjct: 516 SAGLDPAGRCLLPRPKSLAGSC---PSTRLLTLEEAQARTQGRLGTPTEPTTPKAPASPA 572

Query: 289 DAR-GAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVT 347
           + R G     + + GG+SW        GP  PR + L  P     R  P     R  +VT
Sbjct: 573 ERRKGERGEKQRKPGGSSWKTFFALGRGPSVPRKKPL--PWLGGTRAPPQPSGSRPDTVT 630

Query: 348 IDHSR---PASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSPLYLGG 401
           +  ++     SS+  GA  L AG       P +A+ TP  SP R+  P   PL L G
Sbjct: 631 LRSAKSEESLSSQASGAELLGAGGA-----PASATPTPALSPGRSLRPHLIPLLLRG 682



 Score = 38.5 bits (88), Expect = 0.015
 Identities = 45/149 (30%), Positives = 62/149 (41%), Gaps = 25/149 (16%)

Query: 254 LRSSRAPPPARRPLP-CESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTT 312
           L  +RAPP      P   +LR+        S ASG +  GA        GGA  SATPT 
Sbjct: 612 LGGTRAPPQPSGSRPDTVTLRSAKSEESLSSQASGAELLGA--------GGAPASATPTP 663

Query: 313 IPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSS 372
              PG          R+ R  L+P  + G  + +T    +   S+  GA+    G  + S
Sbjct: 664 ALSPG----------RSLRPHLIPLLLRGAEAPLTDACQQEMCSKLRGAQG-PLGPDMES 712

Query: 373 QI--PYTASLTPTPSPPRASPPPFSPLYL 399
            +  P  + L P  +PP   PPP +P  L
Sbjct: 713 PLPPPPLSLLRPGGAPP---PPPKNPARL 738



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 42/146 (28%), Positives = 51/146 (34%), Gaps = 29/146 (19%)

Query: 251  PARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATP 310
            P  L  S    PARRP P E L   +   GPR P+    +  +P             A P
Sbjct: 986  PDHLGYSAPQHPARRPTPPEPLYV-NLALGPRGPSPASSSSSSPP------------AHP 1032

Query: 311  TTIPGPGPPRPQLLVIPRTSRCRLVPAAVVG----RSSSVTIDHSRPASSRGGGARR--- 363
             +   PGPP P+L    R       P  V G        +    + PA  RGG   R   
Sbjct: 1033 RSRSDPGPPVPRLPQKQRAPWGPRTPHRVPGPWGPPEPLLLYRAAPPAYGRGGELHRGSL 1092

Query: 364  ----LRAGTGVSSQIPYTASLTPTPS 385
                 + G G     PY     PTPS
Sbjct: 1093 YRNGGQRGEGAGPPPPY-----PTPS 1113


>gi|194272161 1D-myo-inositol-trisphosphate 3-kinase B [Homo
           sapiens]
          Length = 946

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 59/195 (30%), Positives = 73/195 (37%), Gaps = 30/195 (15%)

Query: 189 SPASCPSRSCPSAAVFILAVAARSCSRRRRV-GTSGPEASTLSSGLLTCSAGEPPTTGGK 247
           SP+ CP RS       +L   ARS  RR +  G   PE S   SG      G P     +
Sbjct: 174 SPSPCPFRSSSQPPGRVLVQGARSEERRTKSWGEQCPETSGTDSG----RKGGPSLCSSQ 229

Query: 248 L-TGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGP------DARGAPTPGR-- 298
           +  G   L    AP  +    P   +R   G   P SP  G       D RG+PTPG   
Sbjct: 230 VKKGMPPLPGRAAPTGSEAQGPSAFVRMEKGI--PASPRCGSPTAMEIDKRGSPTPGTRS 287

Query: 299 ------ARGGGASWSATPTT--IPGPGPPRPQLLVIPRTS-RCRLV-----PAAVVGRSS 344
                    G +   AT     +   GP RPQ L +   S R R +     P A+V R  
Sbjct: 288 CLAPSLGLFGASLTMATEVAARVTSTGPHRPQDLALTEPSGRARELEDLQPPEALVERQG 347

Query: 345 SVTIDHSRPASSRGG 359
                 + PA  RGG
Sbjct: 348 QFLGSETSPAPERGG 362


>gi|39930517 sterile alpha motif domain containing 1 [Homo sapiens]
          Length = 538

 Score = 47.0 bits (110), Expect = 4e-05
 Identities = 52/202 (25%), Positives = 66/202 (32%), Gaps = 44/202 (21%)

Query: 240 EPPTTGGKLTGPARL-RSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGA----- 293
           +PP  G     P R  R + A   A  P P  +   P       +PA  P A  A     
Sbjct: 100 QPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAAATAP 159

Query: 294 PTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRP 353
           P+PG A+ G  +  A P   P P P  P  +  P   R R  P AV  R   +      P
Sbjct: 160 PSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPR-RAPPPAVAAREPPLPPPPQPP 218

Query: 354 ASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP-FSPLYLGGHLRTVFLQGTA 412
           A  +                          P PP+  PPP    +  GG  R V L+   
Sbjct: 219 APPQ-----------------------QQQPPPPQPQPPPEGGAVRAGGAARPVSLREVV 255

Query: 413 DETHQSLAAAFRHRHLGAESGA 434
                        R+LG   GA
Sbjct: 256 -------------RYLGGSGGA 264



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 36/147 (24%), Positives = 50/147 (34%), Gaps = 17/147 (11%)

Query: 256 SSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGA------SWSAT 309
           ++R  PP R   P    R P G     + A+ P     P P       A      + +A 
Sbjct: 96  AARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPPPPAPVAAAAPARAPRAAAAA 155

Query: 310 PTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTG 369
            T  P PGP +P     PR  R   + A     ++        PA +   G RR      
Sbjct: 156 ATAPPSPGPAQPG----PRAQRAAPLAAPPPAPAAP-------PAVAPPAGPRRAPPPAV 204

Query: 370 VSSQIPYTASLTPTPSPPRASPPPFSP 396
            + + P      P   P +  PPP  P
Sbjct: 205 AAREPPLPPPPQPPAPPQQQQPPPPQP 231



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 27/92 (29%), Positives = 35/92 (38%), Gaps = 23/92 (25%)

Query: 237 SAGEPPTTGGKLTGPARLRSS--RAPPPA--------------RRPLPCESLRTPSGTAG 280
           +A  PP+ G    GP   R++   APPPA              R P P  + R P     
Sbjct: 155 AATAPPSPGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRAPPPAVAAREPPLPPP 214

Query: 281 PRSPA-------SGPDARGAPTPGRARGGGAS 305
           P+ PA         P  +  P  G  R GGA+
Sbjct: 215 PQPPAPPQQQQPPPPQPQPPPEGGAVRAGGAA 246



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 30/123 (24%), Positives = 39/123 (31%), Gaps = 12/123 (9%)

Query: 271 SLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTS 330
           S R  +    PR  A+ P    AP    A    A+   TP   P   PP P     P  +
Sbjct: 92  SYRNAARVQPPRRGATPPAPPRAPRGAPAAAAAAAPPPTPAPPP---PPAPVAAAAPARA 148

Query: 331 RCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRAS 390
                 AA    S         P  ++ G   +  A        P        P+ PR +
Sbjct: 149 PRAAAAAATAPPS---------PGPAQPGPRAQRAAPLAAPPPAPAAPPAVAPPAGPRRA 199

Query: 391 PPP 393
           PPP
Sbjct: 200 PPP 202


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
            potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 80/324 (24%), Positives = 109/324 (33%), Gaps = 38/324 (11%)

Query: 91   MCLQEHQSLPG-LPEPPPGSEVPRAAASWQER-----EGPCGTGKGEVTERWSQGQEEGQ 144
            + L  H  LP  +  PPPGS +    A    R     +    +  G  +   S  Q +  
Sbjct: 793  IALTHHPRLPAAIFRPPPGSGLGNLGAGQTPRHLKRLQSLIPSALGSASPASSPSQVDTP 852

Query: 145  RQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSCPSAAVF 204
                  +Q         G+ P   S S  S PP            P +C S S P+ +  
Sbjct: 853  SSSSFHIQQLAGFSAPAGLSPLLPSSS--SSPP------------PGACGSPSAPTPSAG 898

Query: 205  ILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPAR 264
            + A          +    G   S+  S LLT     P   G +   P   + S APP AR
Sbjct: 899  VAATTIAGFGHFHKA--LGGSLSSSDSPLLT-----PLQPGAR--SPQAAQPSPAPPGAR 949

Query: 265  RPL--PCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQ 322
              L  P   L  P  +   RSP+S P   G P    + G      +TP T   P  P P 
Sbjct: 950  GGLGLPEHFLPPPPSS---RSPSSSPGQLGQPPGELSLGLATGPLSTPET--PPRQPEPP 1004

Query: 323  LLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTP 382
             LV   +      P     R       HS         A    +G+  S  +P  +S  P
Sbjct: 1005 SLVAGASGGAS--PVGFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPP 1062

Query: 383  TPSPPRASPPPFSPLYLGGHLRTV 406
               P R   PP +P  L   L+ +
Sbjct: 1063 PQVPQRRGTPPLTPGRLTQDLKLI 1086



 Score = 33.5 bits (75), Expect = 0.49
 Identities = 48/181 (26%), Positives = 63/181 (34%), Gaps = 34/181 (18%)

Query: 224  PEASTLSSGLLTCSAGEPP--TTGGKLTGPARLRSSRAPPPARRPLPCESLR-------- 273
            P  S+ S        G+PP   + G  TGP  L +   PP  R+P P   +         
Sbjct: 961  PPPSSRSPSSSPGQLGQPPGELSLGLATGP--LSTPETPP--RQPEPPSLVAGASGGASP 1016

Query: 274  ---TPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTS 330
               TP G   P   + GP       P RA G   S    P + P P          P+  
Sbjct: 1017 VGFTPRGGLSPPGHSPGPPRTFPSAPPRASGSHGSLLLPPASSPPP----------PQVP 1066

Query: 331  RCRLVPAAVVGRSSS--VTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPR 388
            + R  P    GR +     I  S+PA  + G     RA    S +     S+   P  PR
Sbjct: 1067 QRRGTPPLTPGRLTQDLKLISASQPALPQDGAQTLRRASPHSSGE-----SMAAFPLFPR 1121

Query: 389  A 389
            A
Sbjct: 1122 A 1122


>gi|42544123 splicing factor 1 isoform 3 [Homo sapiens]
          Length = 548

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 51/185 (27%), Positives = 67/185 (36%), Gaps = 27/185 (14%)

Query: 221 TSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGT-- 278
           TSGP  + L+S      A  P         P+ + ++++ PP     P ES R   G   
Sbjct: 332 TSGPATTPLAS------APRPAAPANNPPPPSLMSTTQSRPPWMNSGPSES-RPYHGMHG 384

Query: 279 AGPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGPG--PPRPQLLVIPRTSRCRLV 335
            GP  P  GP +   P P    G GG      P   P P   PP P +   P        
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP----- 439

Query: 336 PAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPP---RASPP 392
                G      +D    ++  G G  RL  G G+    P    + P P PP   +  PP
Sbjct: 440 -----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPP 492

Query: 393 PFSPL 397
           P  PL
Sbjct: 493 PSGPL 497



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 47/177 (26%), Positives = 59/177 (33%), Gaps = 36/177 (20%)

Query: 242 PTTGGKLTGPARLRSSRAP---PPARRPLPCESLRT-----------PSGT--------A 279
           P + G  +GPA    + AP    PA  P P   + T           PS +         
Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385

Query: 280 GPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGP--GPPRPQLLVIPRTSRCRLVP 336
           GP  P  GP +   P P    G GG      P   P P   PP P +   P         
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP------ 439

Query: 337 AAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
               G      +D    ++  G G  RL  G G+    P    + P P PP   PPP
Sbjct: 440 ----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP-PPMGMMPPPPPPPSGQPPP 491


>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
          Length = 638

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 51/185 (27%), Positives = 67/185 (36%), Gaps = 27/185 (14%)

Query: 221 TSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGT-- 278
           TSGP  + L+S      A  P         P+ + ++++ PP     P ES R   G   
Sbjct: 332 TSGPATTPLAS------APRPAAPANNPPPPSLMSTTQSRPPWMNSGPSES-RPYHGMHG 384

Query: 279 AGPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGPG--PPRPQLLVIPRTSRCRLV 335
            GP  P  GP +   P P    G GG      P   P P   PP P +   P        
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP----- 439

Query: 336 PAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPP---RASPP 392
                G      +D    ++  G G  RL  G G+    P    + P P PP   +  PP
Sbjct: 440 -----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPM--GMMPPPPPPPSGQPPPP 492

Query: 393 PFSPL 397
           P  PL
Sbjct: 493 PSGPL 497



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 47/177 (26%), Positives = 59/177 (33%), Gaps = 36/177 (20%)

Query: 242 PTTGGKLTGPARLRSSRAP---PPARRPLPCESLRT-----------PSGT--------A 279
           P + G  +GPA    + AP    PA  P P   + T           PS +         
Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385

Query: 280 GPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGP--GPPRPQLLVIPRTSRCRLVP 336
           GP  P  GP +   P P    G GG      P   P P   PP P +   P         
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP------ 439

Query: 337 AAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
               G      +D    ++  G G  RL  G G+    P    + P P PP   PPP
Sbjct: 440 ----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP-PPMGMMPPPPPPPSGQPPP 491



 Score = 32.0 bits (71), Expect = 1.4
 Identities = 42/176 (23%), Positives = 61/176 (34%), Gaps = 45/176 (25%)

Query: 226 ASTLSSGLLTCSAGE---PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR 282
           ++ + SG+     G+   PP   G +  P    S + PPP   PLP    +       P 
Sbjct: 453 STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP--PWQQQQQQPPPP 510

Query: 283 SPASGPDARGAPTPGRARGGGASWSATPTTIPGPG--PPRPQLLVIPRTSRCRLVPAAVV 340
            P S   A   P P +        + T TT  G G  PP  Q                  
Sbjct: 511 PPPSSSMASSTPLPWQQN------TTTTTTSAGTGSIPPWQQ------------------ 546

Query: 341 GRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPPFSP 396
                      + A++   GA +++   G  + +P    + P P PP A PPP  P
Sbjct: 547 ----------QQAAAAASPGAPQMQ---GNPTMVPLPPGVQP-PLPPGAPPPPPPP 588


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 61/211 (28%), Positives = 78/211 (36%), Gaps = 39/211 (18%)

Query: 217 RRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAP-PPARRPLPCESLRTP 275
           R   T  P+ S LS+G    ++G  P T      PA  R SRA       P P  S R  
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGT----PSPAMARRSRAAGTEVGLPRPAPSARPR 199

Query: 276 SGTAGPRSPASG----------PDARGAPTPG----RARGGGASWSATPTTIPG------ 315
             T GPR   S           P AR  P+ G    R      S SATP + P       
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSA 259

Query: 316 ---------PGPPRP---QLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARR 363
                    P  P+P   Q L  P+ +  R   A  +G  SS  +    P+++    A  
Sbjct: 260 RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPP 319

Query: 364 LRAGTGVSSQIPYTASLTPTP-SPPRASPPP 393
               T  SS +    + TP P +PP  S PP
Sbjct: 320 TLPATPHSSSLTCQLA-TPLPLAPPSPSAPP 349



 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 52/181 (28%), Positives = 72/181 (39%), Gaps = 12/181 (6%)

Query: 220 GTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTA 279
           G   P A   S G ++       TT     G   LR S A     R    E+ +  + +A
Sbjct: 100 GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRIS-AEETVARGKATEAPKRSALSA 158

Query: 280 GPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPP-RPQLLVIPRTSRCRLVPAA 338
           G R   SGP   G P+P  AR   A+   T   +P P P  RP+    P T   R   ++
Sbjct: 159 GARRDTSGPTP-GTPSPAMARRSRAA--GTEVGLPRPAPSARPR----PPTEGPRKSVSS 211

Query: 339 VVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPS---PPRASPPPFS 395
               S++     +R   S GGG +R  + +  SS  P ++     PS    PRA   P  
Sbjct: 212 ASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271

Query: 396 P 396
           P
Sbjct: 272 P 272



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 94/406 (23%), Positives = 136/406 (33%), Gaps = 59/406 (14%)

Query: 51  PRGLEELWVAKLVAGREGEAQPVLVPIAVKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSE 110
           P+GL+ L   ++   R+ +A P L P++   +   A P      + Q+ P LP  P  S 
Sbjct: 274 PKGLQALRPPQVTPPRK-DAAPALGPLS---SSPLATPSPSAALQSQAPPTLPATPHSSS 329

Query: 111 V--------------PRAAASWQEREGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRKA 156
           +              P A  S Q    P  T   + T        +       +  L   
Sbjct: 330 LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPL-SP 388

Query: 157 LVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSRR 216
           L       P A +   L  PP          +SP + PS   P+A    L  A  S    
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPP---ASPPLSPLATPSPQAPNALAVHLLQAPFSPP-- 443

Query: 217 RRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPS 276
                S P  +  S          PP +      P+    S+APP         SL  P 
Sbjct: 444 ----PSPPVQAPFSP------PASPPVS------PSATPPSQAPP---------SLAAPP 478

Query: 277 GTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVP 336
               P  PAS P +  A  P +A       +A P  +  P P  P  L  P        P
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAP---PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 535

Query: 337 AAVVGR---SSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
           A+  G+   S S ++  S  A+        L A      Q+P +   +PT   PR  P P
Sbjct: 536 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL---LQVPPSPPASPTLQAPRRPPTP 592

Query: 394 FSPLYLGGHLRTVFL-QGTADETHQSLAAAFRHRHLGAESGAVSST 438
                + G   T+ L  G      +S ++      L   S + +ST
Sbjct: 593 GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATST 638



 Score = 34.7 bits (78), Expect = 0.22
 Identities = 58/209 (27%), Positives = 71/209 (33%), Gaps = 22/209 (10%)

Query: 191 ASCPSRSCPSAAVFILAV-----AARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTG 245
           A+ P ++ P  A  +L V     A+ +    RR  T GP+ S     L    A  PP   
Sbjct: 556 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP- 614

Query: 246 GKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRS-PASGPDARGAPTPGRARGGGA 304
                P+R  SS    P        +  TP    G  S P  G  A   P    A    A
Sbjct: 615 -----PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPA 669

Query: 305 SWS---ATPTTIPG-PGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVT-----IDHSRPAS 355
           +WS   A P    G PG P P        S   L          S T     +D   P+ 
Sbjct: 670 AWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPG-PSP 728

Query: 356 SRGGGARRLRAGTGVSSQIPYTASLTPTP 384
              GG     AG G SS+ P  A L   P
Sbjct: 729 GTSGGKAAAGAGAGASSRSPKQARLGELP 757



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 38/137 (27%), Positives = 51/137 (37%), Gaps = 7/137 (5%)

Query: 260 PPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGAS-WSATPTTIPGP-G 317
           P  A R  P  S  T S     R PASG   R  P    + G  +S   A+ TT PGP G
Sbjct: 71  PESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG 130

Query: 318 PPRPQLLVIPRTSRCRLVPA---AVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQI 374
               ++      +R +   A   + +   +        P +     ARR RA  G    +
Sbjct: 131 QKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA-AGTEVGL 189

Query: 375 PYTASLTPTPSPPRASP 391
           P  A  +  P PP   P
Sbjct: 190 PRPAP-SARPRPPTEGP 205



 Score = 31.2 bits (69), Expect = 2.4
 Identities = 31/95 (32%), Positives = 40/95 (42%), Gaps = 8/95 (8%)

Query: 221 TSGPEASTLSSGLLTCSAGEPPTTGGK-LTGPARLRSSRAPPPAR-RPLPCESLRTP--- 275
           T GPE++T + G L      P T+GGK   G     SSR+P  AR   LP  +L+     
Sbjct: 709 TEGPESATPAPGALD-PGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 767

Query: 276 --SGTAGPRSPASGPDARGAPTPGRARGGGASWSA 308
                    + A G        PG A GGG +  A
Sbjct: 768 HLLSRTLLLAAAEGAAGGSGGGPGGAEGGGVTGGA 802



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 38/146 (26%), Positives = 50/146 (34%), Gaps = 23/146 (15%)

Query: 190 PASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLT 249
           P+  PS +     +   + +A S     R   SGPE           +A  PP       
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGA--------AASPPPDAELAAC 666

Query: 250 GPARLRSSRAPPPARR-----PLP---------CESLRTPSGTAGPRSPASGPDARG-AP 294
            PA      APP A R     PLP          + L T   T GP S    P A    P
Sbjct: 667 HPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726

Query: 295 TPGRARGGGASWSATPTTIPGPGPPR 320
           +PG + G  A+ +    +   P   R
Sbjct: 727 SPGTSGGKAAAGAGAGASSRSPKQAR 752


>gi|169210256 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 447

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 45/154 (29%), Positives = 62/154 (40%), Gaps = 14/154 (9%)

Query: 226 ASTLSSGLLTCSAGEP--PTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRS 283
           A   S+GL    +G P  P   G+   P    SSR P   +R +   +        GP  
Sbjct: 279 APRTSAGLAGVGSGAPGEPAEPGRARAPRSAPSSREPRQTKRRVGSRARAGAGAVTGP-C 337

Query: 284 PASGPDARGA-PTPGRARGGGASWSATPTTIPGPGPP--RPQLLVIPRTSRCRLVPAAVV 340
           PA+   ARG+ P+P      G +  A PT+ P P  P   P  L   R  R  LVP   +
Sbjct: 338 PAAAQGARGSWPSPRCLPSDGGAREAPPTSAPHPRRPAGSPPALA-DREGRRSLVPQTSI 396

Query: 341 GRSSSVTIDHSRPASSRGG-------GARRLRAG 367
              +   +  +RP + + G         R LRAG
Sbjct: 397 QGQNFAQLSLARPWAGKRGHRQREPEALRALRAG 430



 Score = 36.6 bits (83), Expect = 0.058
 Identities = 44/141 (31%), Positives = 53/141 (37%), Gaps = 35/141 (24%)

Query: 258 RAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPG 317
           R P P   PLP  + RT +G AG  S A G  A     PGRAR         P + P   
Sbjct: 268 RLPDPI--PLPTRAPRTSAGLAGVGSGAPGEPAE----PGRAR--------APRSAPSSR 313

Query: 318 PPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGAR------RLRAGTGVS 371
            PR     +   SR R    AV G           P  +   GAR      R     G +
Sbjct: 314 EPRQTKRRV--GSRARAGAGAVTG-----------PCPAAAQGARGSWPSPRCLPSDGGA 360

Query: 372 SQIPYTASLTPTPSPPRASPP 392
            + P T++  P P  P  SPP
Sbjct: 361 REAPPTSA--PHPRRPAGSPP 379


>gi|116734706 interferon regulatory factor 2 binding protein 2
           isoform B [Homo sapiens]
          Length = 571

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 69/265 (26%), Positives = 101/265 (38%), Gaps = 53/265 (20%)

Query: 138 QGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRS 197
           +G +  +  +ETA QL++A     G  P+  S      PP  A          AS  ++ 
Sbjct: 44  EGADRVEFVIETARQLKRA----HGCFPEGRS------PPGAA----------ASAAAKP 83

Query: 198 CPSAAVFILAVAARSCSRRRRVGTSGPEAS-----TLSSGLLTCSAGEPPTTGGKLTGPA 252
            P +A  IL        +++++G  GPEA+      L    L  +A  PP  G    G +
Sbjct: 84  PPLSAKDILL------QQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDF-GSS 136

Query: 253 RLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDA-RGAPTPGRARGGGASWSATPT 311
           R  +S A PP  +P P   +  P+G +    P   P+  R +P P R        +  PT
Sbjct: 137 RPAASLAQPPTPQPPPVNGILVPNGFSKLEEP---PELNRQSPNPRRGH------AVPPT 187

Query: 312 TIP---GPGPPRPQLLVIPRTSRCRL-----VPAAVVGRSSSVTID-HSRPASSRGGGA- 361
            +P   G   P P  L +   +   L       AA +G +    +  H RPAS     A 
Sbjct: 188 LVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAV 247

Query: 362 -RRLRAGTGVSSQIPYTASLTPTPS 385
               R       Q P  A   P  S
Sbjct: 248 EHEQREAAAKEKQPPPPAHRGPADS 272


>gi|116734704 interferon regulatory factor 2 binding protein 2
           isoform A [Homo sapiens]
          Length = 587

 Score = 46.2 bits (108), Expect = 7e-05
 Identities = 69/265 (26%), Positives = 101/265 (38%), Gaps = 53/265 (20%)

Query: 138 QGQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRS 197
           +G +  +  +ETA QL++A     G  P+  S      PP  A          AS  ++ 
Sbjct: 44  EGADRVEFVIETARQLKRA----HGCFPEGRS------PPGAA----------ASAAAKP 83

Query: 198 CPSAAVFILAVAARSCSRRRRVGTSGPEAS-----TLSSGLLTCSAGEPPTTGGKLTGPA 252
            P +A  IL        +++++G  GPEA+      L    L  +A  PP  G    G +
Sbjct: 84  PPLSAKDILL------QQQQQLGHGGPEAAPRAPQALERYPLAAAAERPPRLGSDF-GSS 136

Query: 253 RLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDA-RGAPTPGRARGGGASWSATPT 311
           R  +S A PP  +P P   +  P+G +    P   P+  R +P P R        +  PT
Sbjct: 137 RPAASLAQPPTPQPPPVNGILVPNGFSKLEEP---PELNRQSPNPRRGH------AVPPT 187

Query: 312 TIP---GPGPPRPQLLVIPRTSRCRL-----VPAAVVGRSSSVTID-HSRPASSRGGGA- 361
            +P   G   P P  L +   +   L       AA +G +    +  H RPAS     A 
Sbjct: 188 LVPLMNGSATPLPTALGLGGRAAASLAAVSGTAAASLGSAQPTDLGAHKRPASVSSSAAV 247

Query: 362 -RRLRAGTGVSSQIPYTASLTPTPS 385
               R       Q P  A   P  S
Sbjct: 248 EHEQREAAAKEKQPPPPAHRGPADS 272


>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
          Length = 639

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 48/178 (26%), Positives = 62/178 (34%), Gaps = 22/178 (12%)

Query: 221 TSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGT-- 278
           TSGP  + L+S      A  P         P+ + ++++ PP     P ES R   G   
Sbjct: 332 TSGPATTPLAS------APRPAAPANNPPPPSLMSTTQSRPPWMNSGPSES-RPYHGMHG 384

Query: 279 AGPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGPG--PPRPQLLVIPRTSRCRLV 335
            GP  P  GP +   P P    G GG      P   P P   PP P +   P        
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP----- 439

Query: 336 PAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
                G      +D    ++  G G  RL  G G+    P      P P P    PPP
Sbjct: 440 -----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPP 492



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 47/177 (26%), Positives = 59/177 (33%), Gaps = 36/177 (20%)

Query: 242 PTTGGKLTGPARLRSSRAP---PPARRPLPCESLRT-----------PSGT--------A 279
           P + G  +GPA    + AP    PA  P P   + T           PS +         
Sbjct: 326 PASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGG 385

Query: 280 GPRSPASGPDARGAPTPGRARG-GGASWSATPTTIPGP--GPPRPQLLVIPRTSRCRLVP 336
           GP  P  GP +   P P    G GG      P   P P   PP P +   P         
Sbjct: 386 GPGGPGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPP------ 439

Query: 337 AAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
               G      +D    ++  G G  RL  G G+    P    + P P PP   PPP
Sbjct: 440 ----GHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPP-PPMGMMPPPPPPPSGQPPP 491



 Score = 32.7 bits (73), Expect = 0.84
 Identities = 44/179 (24%), Positives = 60/179 (33%), Gaps = 35/179 (19%)

Query: 226 ASTLSSGLLTCSAGE---PPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR 282
           ++ + SG+     G+   PP   G +  P    S + PPP   PLP    +       P 
Sbjct: 453 STPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLP--PWQQQQQQPPPP 510

Query: 283 SPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGR 342
            P S   A   P P +        + T TT  G G        IP   + +   AA  G 
Sbjct: 511 PPPSSSMASSTPLPWQQN------TTTTTTSAGTGS-------IPPWQQQQAAAAASPG- 556

Query: 343 SSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRA-----SPPPFSP 396
                      A    G    +    GV   +P  A   P P PP +     +PPP  P
Sbjct: 557 -----------APQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMYAPPPPPP 604


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 52/198 (26%), Positives = 67/198 (33%), Gaps = 39/198 (19%)

Query: 237 SAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPA----------S 286
           +A   P        PA    + APPP   P P    R P   AGP + A          +
Sbjct: 247 AAPPAPAAPSPPAAPAPAAPAAAPPPPP-PAPATLARPPGHPAGPPTAAPAVPPPAAAQN 305

Query: 287 GPDARGAPTPGRARGGGASWSATP-----TTIPGPG-------------PPRPQLLVI-- 326
           G  A  AP P  A GG A  S  P        P PG             PP  Q L    
Sbjct: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASG 365

Query: 327 PRTSRCRLV--PAAVVGRSSSVTIDHSRPASSRG------GGARRLRAGTGVSSQIPYTA 378
           P ++   +V  P       S   +    P +  G      G   +  + T  ++     A
Sbjct: 366 PASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRA 425

Query: 379 SLTPTPSPPRASPPPFSP 396
           +LTPT   PR   PP +P
Sbjct: 426 TLTPTVLAPRLPQPPQNP 443



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 58/187 (31%), Positives = 71/187 (37%), Gaps = 38/187 (20%)

Query: 274 TPSGTAG--PRSPASG-PDARGAPTP-GRAR--GGGASWSATPTT----IP-GPGPPRPQ 322
           +P+G AG  P +PA G P A   P P GRAR  GGG      P+     +P GP PP  +
Sbjct: 66  SPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAK 125

Query: 323 LLVIPRTS--RCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASL 380
           L   P  S   C  VPAA    +       + PA   G  A   RAG G           
Sbjct: 126 LRPPPEGSAGSCAPVPAAAAVAAGPEPAP-AGPAKPAGPAALAARAGPG----------- 173

Query: 381 TPTPSP-PRASPPPFSPLYLGGHLRTVFLQGTADETHQSLAAAFRHRHLGAESGAVSSTN 439
            P P P P   P P  P   G           A +T    AA     H  A + ++ +  
Sbjct: 174 -PGPGPGPGPGPGPGKPAGPG-----------AAQTLNGSAALLNSHHAAAPAVSLVNNG 221

Query: 440 AVAALSL 446
             A L L
Sbjct: 222 PAALLPL 228



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 81/327 (24%), Positives = 106/327 (32%), Gaps = 55/327 (16%)

Query: 97  QSLPGL-PEPPPGSEVPRAAASWQEREGPCGTGKGEVTERWSQGQEEGQRQLETAVQLRK 155
           +  PG  PEPPP     R      +R GP    +  V                 A +LR 
Sbjct: 80  EGAPGAAPEPPPAGRA-RPGGGGPQRPGPPSPRRPLVPAG----------PAPPAAKLRP 128

Query: 156 ALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARSCSR 215
              G  G      + + ++  PE A     +   PA+  +R+ P                
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPG--PGPGPGPGP 186

Query: 216 RRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESLRTP 275
            +  G    +    S+ LL       P       GPA L     P PA    P   ++TP
Sbjct: 187 GKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLP--LPKPAA---PGTVIQTP 241

Query: 276 S--GTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIP------ 327
              G A P +PA+ P    AP P           A P   P P PP P  L  P      
Sbjct: 242 PFVGAAAPPAPAA-PSPPAAPAP-----------AAPAAAPPPPPPAPATLARPPGHPAG 289

Query: 328 RTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQI-PYTASLTPTP-- 384
             +    VP     ++         PA + GG A       GVS Q  P  A+  P P  
Sbjct: 290 PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPA-------GVSGQPGPGAAAAAPAPGV 342

Query: 385 ---SPPR---ASPPPFSPLYLGGHLRT 405
              SP R   A+PP    L   G   T
Sbjct: 343 KAESPKRVVQAAPPAAQTLAASGPAST 369



 Score = 30.8 bits (68), Expect = 3.2
 Identities = 41/170 (24%), Positives = 63/170 (37%), Gaps = 31/170 (18%)

Query: 230 SSGLLTCSAGEPPT---TGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRS--- 283
           ++G +T S    PT   +G + T    + + R P P + P   ++ + P G    RS   
Sbjct: 404 AAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENG 463

Query: 284 -----PASGPDARGAPTPGRARGGGASWSATPT--------TIPGPGPPRPQLLVIPRT- 329
                P        A    + +   A   ATPT        T+  PG P     V P T 
Sbjct: 464 QLLMIPQQALAQMQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTI 523

Query: 330 ------SRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQ 373
                 ++  + P+A + RS  V     +P    GG A+    GT  + Q
Sbjct: 524 IKQVSQAQTTVQPSATLQRSPGV-----QPQLVLGGAAQTASLGTATAVQ 568


>gi|182507165 thymus expressed gene 3-like [Homo sapiens]
          Length = 629

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 90/339 (26%), Positives = 118/339 (34%), Gaps = 51/339 (15%)

Query: 79  VKQAQHRAAPGFMCLQEHQSLPGLPEPPPGSEVPRAAASWQEREGPCGTGKGEVTERWSQ 138
           V+QA   A PG M   E +      E    +   RAAA+ +E+        G V   W  
Sbjct: 41  VQQALRLAQPG-MGGAEAEDEEDADEDEDAAAARRAAAALEEQLEAL---PGLV---WDL 93

Query: 139 GQEEGQRQLETAVQLRKALVGDRGVIPQACSQSWLSLPPELADFCLCQRVSPASCPSRSC 198
           GQ+ G   LE+   L +      G      S      PP  + FC     S +S   R  
Sbjct: 94  GQQLGDLSLESG-GLEQESGRSSGFYEDPSSTGGPDSPP--STFCGDSGFSGSSSYGRLG 150

Query: 199 PSAAVFILAVAARSCSRRRRVGTSGPEASTL--SSGLLTCSAGEPPTTGGKLTGP----- 251
           PS    I A       R + +G + P A  +  +   +  S   P  T G   GP     
Sbjct: 151 PSEPRGIYA-----SERPKSLGDASPSAPEVVGARAAVPRSFSAPYPTAGGSAGPEACSS 205

Query: 252 ARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTP-----------GRAR 300
           A  R+   P     PL   ++R+P     P  P   PDA GA  P            R R
Sbjct: 206 AERRARAGPFLTPSPLHAVAMRSPRPCGRP--PTDSPDAGGAGRPLDGYISALLRRRRRR 263

Query: 301 GGGASWSATPTTIPG--PGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRG 358
           G G      P T PG   G PR Q  V  R       P +              P+  R 
Sbjct: 264 GAGQ-----PRTSPGGADGGPRRQNSVRQRPPDASPSPGSARPARE--------PSLERV 310

Query: 359 GGARRLRAGTGVSSQIPYTASLTPTPSPPRASP-PPFSP 396
           GG     A    +    + +   P P+ P A+P PP SP
Sbjct: 311 GGHPTSPAALSRAWASSWESEAAPEPAAPPAAPSPPDSP 349



 Score = 30.0 bits (66), Expect = 5.4
 Identities = 60/245 (24%), Positives = 75/245 (30%), Gaps = 52/245 (21%)

Query: 158 VGDRGVIPQACSQSWLS-----LPPELADFCLCQRVSPASCPSRSCPSAAVFILAVAARS 212
           VG     P A S++W S       PE A        SP   P+      A +I    A +
Sbjct: 310 VGGHPTSPAALSRAWASSWESEAAPEPA--APPAAPSPPDSPAEGRLVKAQYIPGAQAAT 367

Query: 213 CSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTGPARLRSSRAPPPARRPLPCESL 272
                R     P   T    +      E P   G+    A     R  P AR+    +S 
Sbjct: 368 RGLPGRAARRKPPPLTRGRSVEQSPPRERPRAAGRRGRMAEASGRRGSPRARKASRSQSE 427

Query: 273 RTPSGTAG--PRSPASGPDA-RGAPTPGRARGGGAS------------WSATP------- 310
            +  G A   P  P   P A R  P P R R G A             W +T        
Sbjct: 428 TSLLGRASAVPSGPPKYPTAEREEPRPPRPRRGPAPTLAAQAAGSCRRWRSTAEIDAADG 487

Query: 311 ---------TTIPGPGP----PRPQLL--VIPRTSRCRLVPAAVVGRSSSVTIDHSRPAS 355
                      +PGPGP    P+ +LL       S C       +GR          PA 
Sbjct: 488 RRVRPRAPAARVPGPGPSPSAPQRRLLYGCAGSDSECSAGRLGPLGRRG--------PAG 539

Query: 356 SRGGG 360
             GGG
Sbjct: 540 GVGGG 544


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 39/118 (33%), Positives = 48/118 (40%), Gaps = 9/118 (7%)

Query: 187 RVSPASCPSRSCPSAAVFILAVAARSCSRRRRV----GTSGPEASTLSSGLLTCSAGEPP 242
           R  P SC +R CPS A   L     +   R+R       + PE   + +  L  SA  P 
Sbjct: 63  RTHPGSCRAR-CPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPA 121

Query: 243 TTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRAR 300
                L    RL     PPP R  LP   L      + P SPA  P +R AP PG A+
Sbjct: 122 PGRDAL----RLPPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPGHAQ 175


>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
          Length = 1682

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 49/163 (30%), Positives = 65/163 (39%), Gaps = 22/163 (13%)

Query: 243 TTGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPR-----SPASGPDARGAPTPG 297
           TT    T  A     + PPPA  P P  +   P     P      SPAS   +  +   G
Sbjct: 754 TTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEG 813

Query: 298 RA---RGGGASWSATPTTIP----GPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDH 350
           +    RG GA+ S  P  +P     PGPP     + P ++      +     SSS     
Sbjct: 814 QKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSS----- 868

Query: 351 SRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
           S+ ++S G  AR  RAG     + P    +TPT  PP  S PP
Sbjct: 869 SQFSTSGGPWARERRAG-----EEPVPGPMTPTQPPPPLSLPP 906



 Score = 34.3 bits (77), Expect = 0.29
 Identities = 25/77 (32%), Positives = 33/77 (42%), Gaps = 13/77 (16%)

Query: 245 GGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGA 304
           G K  GP   R+  A PP  +P+P  +L  PSG  G            +P   R RG  +
Sbjct: 189 GAKRGGPPVKRA--AEPPVVQPVPPAALSGPSGEEGL-----------SPGGKRRRGCNS 235

Query: 305 SWSATPTTIPGPGPPRP 321
             +  P  +P P PP P
Sbjct: 236 EQTGLPPGLPLPPPPLP 252



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 33/122 (27%), Positives = 43/122 (35%), Gaps = 23/122 (18%)

Query: 266 PLPCE--SLRTPSGTAGPRSPASGPDARGAPTPGRARG-----GGASWS----------- 307
           PLP    S   PSG       ++ P A+G+P P  +        G  W+           
Sbjct: 831 PLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVP 890

Query: 308 --ATPTTIPGP---GPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGAR 362
              TPT  P P    P R +  V+   SR        VGRS++   D    A     G  
Sbjct: 891 GPMTPTQPPPPLSLPPARSESEVLEEISRACETLVERVGRSATDPADPVDTAEPADSGTE 950

Query: 363 RL 364
           RL
Sbjct: 951 RL 952



 Score = 29.6 bits (65), Expect = 7.1
 Identities = 48/192 (25%), Positives = 62/192 (32%), Gaps = 47/192 (24%)

Query: 215 RRRRVGTSGPEASTLSSGLLTC---SAGEPPTTGGKLTGPARLRSSRAPPPARRPLP--- 268
           R  RV  S  ++S   +    C   +   PP   G  T  +   SS        P P   
Sbjct: 361 RESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIP 420

Query: 269 -CESLRTPS------GTAGPRSPASGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRP 321
             +  +TP+      G  GP + +S     GAP            +ATP     PGP  P
Sbjct: 421 GADHYQTPALEVSHHGRLGPSAHSSRKPFLGAP------------AATPHLSLPPGPSSP 468

Query: 322 QLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGVSSQIPYTASLT 381
                PR  R    PA + G +        R A   G     L  GT             
Sbjct: 469 PPPPCPRLLRPPPPPAWLKGPAC-------RAAREDGEILEELFFGT------------- 508

Query: 382 PTPSPPRASPPP 393
               PPR +PPP
Sbjct: 509 --EGPPRPAPPP 518


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 73/297 (24%), Positives = 110/297 (37%), Gaps = 58/297 (19%)

Query: 186 QRVSPASCPSRSCPSAAVFILAVAARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTG 245
           +R +P+  P R  PS   +   +       +RR   S P          T S   PP   
Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPI-------QRRYSPSPPPKRR------TASPPPPPKRR 624

Query: 246 GKLTGPARLRSSRAPPPARRPLPCESLRTPS-------------GTAGPRSPASGPDARG 292
              + P + R S +PPP +R  P    R+PS              T   RSP   P+ R 
Sbjct: 625 ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQ--PNKRH 682

Query: 293 APTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLV----------------P 336
           +P+P R R    S S  P        P+ +    P T   R V                P
Sbjct: 683 SPSP-RPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741

Query: 337 AAVVGRSSSVTIDHS-RPASSR----GGGARRLRAGTGVSSQIPYTASLTPTPSPPRASP 391
            +V   SSS ++  S  PA+ +        +     T  S  +P   + +PTPSP   SP
Sbjct: 742 QSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSP---SP 798

Query: 392 PPFSPLYLGGHLRTVFLQGTADETHQSLAAAFRH-RHLGAESGAVSSTNAVAALSLA 447
           P  S    GG  +    +   D+ H+      +H +H   ++ A ++  AV   ++A
Sbjct: 799 PRNSDQEGGGKKK----KKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAVTPAAIA 851



 Score = 37.4 bits (85), Expect = 0.034
 Identities = 53/166 (31%), Positives = 65/166 (39%), Gaps = 24/166 (14%)

Query: 237 SAGEPPTTGGKLTGPARLRSSRAPPPARR--PLPCESLRTPSGTAGPRSPA----SGP-D 289
           S   PPT   +   PA       PPP RR  P P    RTPS     RSP+    S P  
Sbjct: 549 SPSPPPTRRRRSPSPA-------PPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQ 601

Query: 290 ARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTID 349
            R +P+P   R   AS    P     P PP  + +      + R  P     RS S++  
Sbjct: 602 RRYSPSPPPKR-RTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSP-VTKRRSPSLSSK 659

Query: 350 HSRPASSRGGGARRLRAGTGVSSQIPYTASLTPTPSPPR--ASPPP 393
           H R  SS     R  R     S Q     S +P P  P+  +SPPP
Sbjct: 660 H-RKGSSPSRSTREAR-----SPQPNKRHSPSPRPRAPQTSSSPPP 699



 Score = 35.0 bits (79), Expect = 0.17
 Identities = 45/165 (27%), Positives = 60/165 (36%), Gaps = 26/165 (15%)

Query: 253 RLRSSRAPPPARRPLPCESLRTPSGTAGP------RSPASGPDAR----GAPTPGRARGG 302
           R R SR+P P RR  P    R  S +  P      RSP+  P+ +      P P      
Sbjct: 173 RRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKE 232

Query: 303 GASWSATPTT----IPGPGP-PRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSR 357
            +   AT T+    +P P P P P+     + S+          RS S +   SR  S  
Sbjct: 233 PSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRS 292

Query: 358 GGGARRLRAGTGVSSQIPYTASLTPTP---------SPPRASPPP 393
               R  R     S    Y+    P+P         +PPR  PPP
Sbjct: 293 PSHTRPRRRHRSRSRS--YSPRRRPSPRRRPSPRRRTPPRRMPPP 335



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 44/151 (29%), Positives = 57/151 (37%), Gaps = 28/151 (18%)

Query: 252 ARLRS-SRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGGASWSATP 310
           +R RS SR+   +R P      R     +   SP   P  R  P+P R          TP
Sbjct: 278 SRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR---------TP 328

Query: 311 TTIPGPGPPRPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGGGARRLRAGTGV 370
                P PPR +    P   R R   A++ G SSS +   SR    +             
Sbjct: 329 PRRMPP-PPRHRRSRSP-VRRRRRSSASLSGSSSSSSSSRSRSPPKK--------PPKRT 378

Query: 371 SSQIPYTASLTPTPSPPR--------ASPPP 393
           SS    T  L+P+ SPPR        A+PPP
Sbjct: 379 SSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409



 Score = 30.4 bits (67), Expect = 4.2
 Identities = 35/124 (28%), Positives = 49/124 (39%), Gaps = 12/124 (9%)

Query: 210 ARSCSRRRRVGTSGPEASTLSSGLLTCSAGEPPTTGGKLTG--PARLR--SSRAPPPARR 265
           +RS  RRRR  ++    S+ SS   +  +  PP    K T   P + R  S  A PP RR
Sbjct: 341 SRSPVRRRRRSSASLSGSSSSSS--SSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR 398

Query: 266 PLPCESLRTPSGTAGPRSPASG---PDARGAPTPGRARGGGASWSAT---PTTIPGPGPP 319
             P      P  T    +P        +R + +PGR  G       T    +  P P P 
Sbjct: 399 HRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPR 458

Query: 320 RPQL 323
           + +L
Sbjct: 459 KVEL 462


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 47/154 (30%), Positives = 50/154 (32%), Gaps = 31/154 (20%)

Query: 244 TGGKLTGPARLRSSRAPPPARRPLPCESLRTPSGTAGPRSPASGPDARGAPTPGRARGGG 303
           TGG       LR    PPP            P    GP  P   P   G P P  ARG G
Sbjct: 262 TGGVEAVKNELRRQAPPPP------------PPSRGGPPPPPPPPHNSGPPPP-PARGRG 308

Query: 304 A---SWSATPTTIPGPGPP-RPQLLVIPRTSRCRLVPAAVVGRSSSVTIDHSRPASSRGG 359
           A     S  PT  P P PP RP + V P        P      SS+ +     P S  G 
Sbjct: 309 APPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGV 368

Query: 360 GARRLRAGTGVSSQIPYTASLTPTPSPPRASPPP 393
           G              P      P P PP   PPP
Sbjct: 369 G--------------PVAPPPPPPPPPPPGPPPP 388



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 48/171 (28%), Positives = 61/171 (35%), Gaps = 25/171 (14%)

Query: 241 PPTTGGKLTGPARLRSSRAPPPAR------------RPLPCESLRTPSGTAGPRSPA--- 285
           PP   G    PAR R +  PPP+R            RP        P+    P  PA   
Sbjct: 293 PPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPS 352

Query: 286 SGPDARGAPTPGRARGGGASWSATPTTIPGPGPPRPQLL------VIPRT--SRCRLVPA 337
           S P     P P     G  +    P   P PGPP P  L       +P T  ++  L+  
Sbjct: 353 SAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPPPGLPSDGDHQVPTTAGNKAALLDQ 412

Query: 338 AVVGRSSSVTIDHSRPASSRGGGA--RRLRAGTGVSSQIPYTASLTPTPSP 386
              G        +SRP S  G  A   ++R G  + S      S  PTP+P
Sbjct: 413 IREGAQLKKVEQNSRPVSCSGRDALLDQIRQGIQLKSVADGQESTPPTPAP 463


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.402 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,883,361
Number of Sequences: 37866
Number of extensions: 1811088
Number of successful extensions: 14328
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 1192
Number of HSP's that attempted gapping in prelim test: 10004
Number of HSP's gapped (non-prelim): 4639
length of query: 528
length of database: 18,247,518
effective HSP length: 107
effective length of query: 421
effective length of database: 14,195,856
effective search space: 5976455376
effective search space used: 5976455376
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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