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Search of human proteins with 238908524
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
(1015 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238908524 hypothetical protein LOC389333 [Homo sapiens] 2089 0.0
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 125 2e-28
gi|163965366 nascent polypeptide-associated complex alpha subuni... 106 1e-22
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 96 2e-19
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 95 4e-19
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 94 5e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 88 5e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 88 5e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 88 5e-17
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 88 5e-17
gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sap... 84 5e-16
gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sap... 84 5e-16
gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sap... 84 5e-16
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 84 7e-16
gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapi... 84 9e-16
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 81 6e-15
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 79 2e-14
gi|47132519 Ras association and pleckstrin homology domains 1 is... 74 5e-13
gi|110349719 titin isoform N2-A [Homo sapiens] 72 3e-12
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 72 3e-12
gi|160707881 formin 2 [Homo sapiens] 71 6e-12
gi|150170670 piccolo isoform 2 [Homo sapiens] 70 1e-11
gi|150378539 piccolo isoform 1 [Homo sapiens] 70 1e-11
gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens] 69 2e-11
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 69 3e-11
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens] 68 4e-11
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 68 5e-11
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 67 9e-11
gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sap... 66 1e-10
gi|110832843 TBP-associated factor 4 [Homo sapiens] 65 2e-10
>gi|238908524 hypothetical protein LOC389333 [Homo sapiens]
Length = 1015
Score = 2089 bits (5412), Expect = 0.0
Identities = 1015/1015 (100%), Positives = 1015/1015 (100%)
Query: 1 MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVA 60
MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVA
Sbjct: 1 MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVA 60
Query: 61 PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPL 120
PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPL
Sbjct: 61 PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPL 120
Query: 121 FGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSP 180
FGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSP
Sbjct: 121 FGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSP 180
Query: 181 AAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDES 240
AAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDES
Sbjct: 181 AAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDES 240
Query: 241 LGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPL 300
LGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPL
Sbjct: 241 LGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPL 300
Query: 301 RVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPR 360
RVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPR
Sbjct: 301 RVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPR 360
Query: 361 EAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDR 420
EAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDR
Sbjct: 361 EAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDR 420
Query: 421 TTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWE 480
TTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWE
Sbjct: 421 TTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWE 480
Query: 481 IPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNG 540
IPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNG
Sbjct: 481 IPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNG 540
Query: 541 LTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDA 600
LTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDA
Sbjct: 541 LTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDA 600
Query: 601 DKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEG 660
DKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEG
Sbjct: 601 DKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEG 660
Query: 661 GESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRA 720
GESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRA
Sbjct: 661 GESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRA 720
Query: 721 ENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLG 780
ENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLG
Sbjct: 721 ENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLG 780
Query: 781 GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL 840
GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL
Sbjct: 781 GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL 840
Query: 841 ALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQP 900
ALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQP
Sbjct: 841 ALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQP 900
Query: 901 RLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQA 960
RLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQA
Sbjct: 901 RLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQA 960
Query: 961 LGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL 1015
LGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL
Sbjct: 961 LGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL 1015
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 125 bits (314), Expect = 2e-28
Identities = 250/1030 (24%), Positives = 355/1030 (34%), Gaps = 169/1030 (16%)
Query: 74 SAQNSRQRHGPGSGFPRGPGSGPRPPQP----QLRTLPSGEMEVIFGVGPLF----GCSG 125
+A + PG PR PGS PRPP P LR L + G PL G G
Sbjct: 12 AAARTPAARAPGLLTPRPPGS-PRPPPPVTPAALRVLGAAGA---VGRKPLAERAGGIGG 67
Query: 126 ADDREAQQQFTEPAFISPLPPGPAS-PAAVPRQSQVPDGGSRWATYLEL--RPRGPSPAA 182
A E+ + PAS P A R + P + + R G +
Sbjct: 68 ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 127
Query: 183 PAQFECVEVALEEGAAPARPRTVPKRQ-IELRPRPQSPPRAAGAPRPRLLLRTGSLDESL 241
P + + ++ EE A + PKR + R + G P P + R+ + +
Sbjct: 128 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 187
Query: 242 G------------PLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTH 289
G P + V +A + +PA G P +R + S
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 247
Query: 290 VVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEP-------LGPVSSSI 342
+ A+S P APA +P P + ++ +P T P LGP+SSS
Sbjct: 248 PLSSPARSGPSARGTPRAPAHPSQPKP----KGLQALRPPQVTPPRKDAAPALGPLSSSP 303
Query: 343 FLQSEEKIQEARKTRFP-REAPDRTVQRARSPPFECRIPSEVPSRAVRPRS---PSPPRQ 398
+AR P A SPP +P PS + P PSPP
Sbjct: 304 LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363
Query: 399 TPNGA---VRGPRCPSPQNLS-------PWDRTTRRVSSPLFPEASSEWENQ----NPAV 444
P+ A + P +P +L P T+ + +P P A S + +P +
Sbjct: 364 PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423
Query: 445 EETVSRRSPSP-----PILSQWNQCVAGERSPSLEAP-SLWEIP--HSAVADAVEPRSSP 496
+ T S + SP + S SP L+AP SL P ++++ AV P SSP
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483
Query: 497 SPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGT 556
P +A S + P P SS+ TQ LAPP+ P
Sbjct: 484 L--TIHPLQAL---------SSLASHSPQAPLSSLIMPPLE----TQSSLAPPSLQTP-- 526
Query: 557 PEPTEMQSPSTREISDLAFGGSQQS------PEVAAPEPPGSHPVGTLDADKCPEVLGPG 610
P + +P + LA Q + P + P P P L A P P
Sbjct: 527 --PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP---LQAPPSPLTTPPP 581
Query: 611 EAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPA 670
E S +A P P+ AP A GLP+PP P PP
Sbjct: 582 ETPSS---IATPPPQ----------APPALASPPLQGLPSPPLSPLAT---------PPP 619
Query: 671 LGPPAPAHYTSVFIKDFLPVVPHPYEPP-EPSFDTVARDASQPNGVLRRRAENSTAKPFK 729
PP A LP + P PP P +A + Q L + P
Sbjct: 620 QAPPXLA----------LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669
Query: 730 RTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRL-VPDGDGRTSPLGGARSSSQR 788
++ P + P V+ A P + A L VP + P+ + + +
Sbjct: 670 SPPVQAP--FSPPASPPVSPS--ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 789 SPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQ----APLPREPLALAG 844
+P A P SP SP P P+ PP P V A LP PLA
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLA--- 782
Query: 845 RTAPAQPRAASAPPTDRSPQSPSQGARRQP----GAAPLGKVLVDPESGRYYFVEAP--- 897
+ P P A + PP P P+ + P + P+ + P +AP
Sbjct: 783 KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP-------QAPPVL 835
Query: 898 RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTP---LALGLGLYPP-AYGPIPSLSLP 953
P L+V P + ++ P +PGP V P LAL G PP + P +LS P
Sbjct: 836 AAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGP 895
Query: 954 PSPG--PQALGSPQLPWVSEAGPLDGTYYLP-----------VSGTPNPAPPLLLCAPPS 1000
G A +P+ ++GP G P + + PAPPL P
Sbjct: 896 DLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPG 955
Query: 1001 SSGPTQPGKG 1010
+ P P G
Sbjct: 956 APLPWPPATG 965
Score = 114 bits (284), Expect = 6e-25
Identities = 263/1048 (25%), Positives = 354/1048 (33%), Gaps = 237/1048 (22%)
Query: 7 PPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAG 66
P + P + AP + S G S A G+ P +G + VA G+
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 67 AQPRLSVSAQNSRQRHGPGSGFP----------RGPGSGPRPPQPQLRTLPSGEMEVIFG 116
A R ++SA R GP G P G G P P R P E
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE------ 203
Query: 117 VGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPR 176
GP S A + TEP+ + P P + S AT L R
Sbjct: 204 -GPRKSVSSASEHST----TEPSPAARRRPSAGGGLQRPASRSL----SSSATPLSSPAR 254
Query: 177 -GPS----PAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLL 231
GPS P APA P++P+ PK LRP +PPR AP
Sbjct: 255 SGPSARGTPRAPAH-------------PSQPK--PKGLQALRPPQVTPPRKDAAP----- 294
Query: 232 LRTGSLDESLGPLQAAAGFVQTALARKLSPEA-PAPSSATFGSTGRSEPETRETARSTHV 290
+LGPL + SP A P+PS
Sbjct: 295 --------ALGPLSS-------------SPLATPSPSG---------------------- 311
Query: 291 VLEKAKSRPLRVRDNSA-PAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEK 349
K+RP+ DN+A P A P PS P PL P S S S +
Sbjct: 312 ----TKARPVPPPDNAATPLPATLP-PS---------PPLATPLPLAPPSPSA-PPSLQT 356
Query: 350 IQEARKTRFPREAPDRTVQRARSPPFECRIPS-EVPSRAVRPRSPSPPRQTPNGAVRGPR 408
+ T + P T ++PP IP +VP P +P
Sbjct: 357 LPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAP------------- 403
Query: 409 CPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGE 468
PSP LS TT S L +A+ + +P + S SPS P +
Sbjct: 404 -PSPLALSSLQATTSLGSPTL--QATHSFLTMSPR-QTQASLTSPSRPASTP-------P 452
Query: 469 RSPSLEAP-SLWEIP--HSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPM 525
SP L+AP SL P ++++ AV P SSP P +A S + P
Sbjct: 453 DSPPLQAPLSLPASPPLQTSLSPAVSPLSSPL--TIHPLQA---------LSSLASHSPQ 501
Query: 526 GPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLA------FGGSQ 579
P SS+ TQ LAPP+ P P + +P + LA
Sbjct: 502 APLSSLIMPPLE----TQSSLAPPSLQTP----PASLTTPPLENLPSLAPPPLQTASAPL 553
Query: 580 QSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGF 639
+P + P P P L A P P E S +A P P+ AP
Sbjct: 554 TTPHLETPPCPAPCP---LQAPPSPLTTPPPETPSS---IATPPPQ----------APPA 597
Query: 640 PAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPP- 698
A GLP+PP P PP PP A LP + P PP
Sbjct: 598 LASPPLQGLPSPPLSPLA---------TPPPQAPPXLA----------LPPLQAPPSPPA 638
Query: 699 EPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGG 758
P +A + Q L + P ++ P + P V+ A P
Sbjct: 639 SPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP--FSPPASPPVSP--SATPPSQ 694
Query: 759 ENRDVEAQRL-VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPK 817
+ A L VP + P+ + + ++P A P SP SP P
Sbjct: 695 APPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPP 754
Query: 818 PKTPPTAPEPAAAV----QAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQ 873
P+ PP P V A LP PLA + P P A + PP P P+ +
Sbjct: 755 PRVPPLLAAPPLQVPPSPPASLPMSPLA---KPPPQAPPALATPPLQALPSPPASFPGQA 811
Query: 874 P----GAAPLGKVLVDPESGRYYFVEAP---RQPRLRVLFDPESGQYVEVLLPPSSPGPP 926
P + P+ + P +AP P L+V P + ++ P +PGP
Sbjct: 812 PFSPSASLPMSPLATPPP-------QAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 927 HRVYTP---LALGLG-LYPPAYGPIPSLSLPPSPG--PQALGSPQLPWVSEAGPLDGTYY 980
V P LAL G PP+ P +LS P G A +P+ ++GP G
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG--- 921
Query: 981 LPVSGTPNPAPPLLLCAPPS-SSGPTQP 1007
+ +P P L C P + S GP P
Sbjct: 922 --AAASPPPDAELAACHPAAWSRGPAPP 947
Score = 99.0 bits (245), Expect = 2e-20
Identities = 197/845 (23%), Positives = 282/845 (33%), Gaps = 129/845 (15%)
Query: 212 LRPRPQSPPRAAGAPRP---RLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSS 268
L PRP PR P R+L G++ PL AG + A + +P A S
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIGGATIPESAPRAGPTRS 82
Query: 269 ATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKP 328
A T P +R A + + PAK P P +
Sbjct: 83 A---GTSSRNPASRPPASGRG--------------ERAPPAKNTSPGP------VSSPGR 119
Query: 329 APGTEPLGPVSSS-IFLQSEEKIQEARKTRFPREAP------------------DRTVQR 369
A GT GP+ + + +EE + + T P+ + +R
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 370 ARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSP---QNLSPWDRTTRRVS 426
+R+ E +P PS RP + P + + + PSP + S R S
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 427 SPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEA--PSLWEIPHS 484
L +SS +PA +R +P P + + L+A P P
Sbjct: 240 RSL---SSSATPLSSPARSGPSARGTPRAPAHP------SQPKPKGLQALRPPQVTPPRK 290
Query: 485 AVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQE 544
A A+ P SS P RP+ P P P+ A + T
Sbjct: 291 DAAPALGPLSSSPLATPSPSGTKARPV----PPPDNAATPLP-----ATLPPSPPLATPL 341
Query: 545 ELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCP 604
LAPP+PSAP P + SP A SQ P + P + T+ + P
Sbjct: 342 PLAPPSPSAP--PSLQTLPSPP-------ATPPSQAPPSMTTPPMQAPPSLQTIPPIQVP 392
Query: 605 EVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESK 664
L + A P P + L TT A S L P S+
Sbjct: 393 HSL------TSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSR 446
Query: 665 TQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENST 724
P PP A + LP P P + S S P + +A +S
Sbjct: 447 PASTPPDSPPLQAPLS-------LPASP----PLQTSLSPAVSPLSSPLTIHPLQALSSL 495
Query: 725 AKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARS 784
A + + +L + P + ++ P + A P + S
Sbjct: 496 ASHSPQAPL---SSLIM---PPLETQSSLAPPSLQTPP--ASLTTPPLENLPSLAPPPLQ 547
Query: 785 SSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTP-----PTAPEPAAAVQAPL---P 836
++ P P P +QA PSP P P+TP P P A PL P
Sbjct: 548 TASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLP 607
Query: 837 REPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEA 896
PL+ P P + PP ++P SP P A P + P + + ++A
Sbjct: 608 SPPLSPLATPPPQAPPXLALPPL-QAPPSPPASPPLSPLATPSPQA---PNALAVHLLQA 663
Query: 897 P----RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSL 952
P P ++ F P + V P S PP PL + PPA P+ +
Sbjct: 664 PFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS--PPASPPMSPSAT 721
Query: 953 PPSPGPQALGSP--QLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKG 1010
PP P L +P Q+P A P + S TP P P LL APP P+ P
Sbjct: 722 PPPQAPPPLAAPPLQVPPSPPASPP-----MSPSATPPPRVPPLLAAPPLQVPPSPPASL 776
Query: 1011 SLFPL 1015
+ PL
Sbjct: 777 PMSPL 781
Score = 88.2 bits (217), Expect = 4e-17
Identities = 207/940 (22%), Positives = 296/940 (31%), Gaps = 151/940 (16%)
Query: 14 PRQLPTAPARRQDSSGSSGSYYTAPGSPEPP------DVGPDAKGPANWPWVAPGRGAGA 67
P++ + R+D+SG + PG+P P G + P P P R
Sbjct: 151 PKRSALSAGARRDTSGPT------PGTPSPAMARRSRAAGTEVGLPRPAPSARP-RPPTE 203
Query: 68 QPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGAD 127
PR SVS+ + P R P +G +P R+L S + G
Sbjct: 204 GPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP 263
Query: 128 DREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAA---PA 184
A +P + L P +P PR+ P L P SP A P+
Sbjct: 264 RAPAHPSQPKPKGLQALRPPQVTP---PRKDAAP----------ALGPLSSSPLATPSPS 310
Query: 185 QFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPL 244
+ V + AA P T+P P P +PP + P + L + S P
Sbjct: 311 GTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPP 370
Query: 245 QAAAGFVQTALARKLSPEAPAPSSAT------------FGSTGRSEPETRETARSTHVVL 292
+Q + + P P S T S + T ++TH L
Sbjct: 371 SMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFL 430
Query: 293 EKA-KSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTE---PLGPVSSSIFLQSEE 348
+ + + S PA P P L+ P T + P+SS + + +
Sbjct: 431 TMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ 490
Query: 349 KIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPP--RQTPNGAVRG 406
+ +P + PP E + PS P S + P P+ A
Sbjct: 491 ALSSLAS-----HSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLA--- 542
Query: 407 PRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVE---ETVSRRSPSPPILSQWNQ 463
P P + TT + +P P +P ET S + PP
Sbjct: 543 ---PPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPP------- 592
Query: 464 CVAGERSPSLEAPSLWEIPHSAVAD-AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETW 522
+ P+L +P L +P ++ A P +P A P +AP P + SP T
Sbjct: 593 ----QAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATP 648
Query: 523 DPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSP 582
P P N L L P P P P++ +S A SQ P
Sbjct: 649 SPQAP-----------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 697
Query: 583 EVAAP------EPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPR--PRDVRKLVKTT 634
+AAP PP S P+ A P+ P A P + +P P T
Sbjct: 698 SLAAPPLQVPPSPPASPPMSP-SATPPPQAPPPLAA----PPLQVPPSPPASPPMSPSAT 752
Query: 635 YAPGFPAGAQGSGLPAPPADPCG---EEGGESKTQEPPALGPPA-------PAHYTSVFI 684
P P L PP+ P + Q PPAL P PA +
Sbjct: 753 PPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ-- 810
Query: 685 KDFLPVVPHPYEP---PEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIR--LPGAL 739
F P P P P P V L + + A P + R PG
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLA------APLLQVPPSPPASPTLQAPRRPPTPGPD 864
Query: 740 ALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAG--VR 797
P +T + P +R + PD G +S + GP G
Sbjct: 865 TSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA 924
Query: 798 SPRPGS---------------PQMQASPSPGIAPKPKTPPTAPE-------------PAA 829
SP P + P + +PG AP P P T P P +
Sbjct: 925 SPPPDAELAACHPAAWSRGPAPPLAFRGAPG-APLPWPPATGPGSADGLCTIYETEGPES 983
Query: 830 AVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQG 869
A AP +P G + A A + RSP+ G
Sbjct: 984 ATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 1023
Score = 57.0 bits (136), Expect = 9e-08
Identities = 146/623 (23%), Positives = 204/623 (32%), Gaps = 117/623 (18%)
Query: 3 TALAPPALPGIPRQLPTAPARRQDSSG-----SSGSYYTAPGSPEPPDVGPDAKGPANWP 57
++LAPP+L P L T P S ++ + T P PP PA P
Sbjct: 516 SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPP-------CPAPCP 568
Query: 58 WVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGV 117
AP P P S P + P P L+ LPS + +
Sbjct: 569 LQAPPSPLTTPP-----------PETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATP 617
Query: 118 GPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRG 177
P +A P +P P PASP P + P + A +L P
Sbjct: 618 PP----------QAPPXLALPPLQAP-PSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 666
Query: 178 PSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSL 237
P P+ P Q AP P P P Q+PP A P L+
Sbjct: 667 PPPSPPVQ------------APFSPPASPPVSPSATPPSQAPPSLAAPP-----LQVPPS 709
Query: 238 DESLGPLQAAAGFVQTALARKLSPEAPAPSSA---TFGSTGRSEPETRETARSTHVVLEK 294
+ P+ +A P+AP P +A + + P +A V
Sbjct: 710 PPASPPMSPSA---------TPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPL 760
Query: 295 AKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEAR 354
+ PL+V S PA P S + + PA T PL + S
Sbjct: 761 LAAPPLQV-PPSPPASLPM---SPLAKPPPQAPPALATPPLQALPSP------------- 803
Query: 355 KTRFPREAPDRTVQRARSPPFECRIPSEVPSRA--VRPRSPSPPRQTPNGAVRGPRCPSP 412
FP +AP P P P A + PSPP A R P P P
Sbjct: 804 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGP 863
Query: 413 QNLSPWDRTTRRVS--SPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERS 470
R T ++ P P S P + S + +P L ++ +G
Sbjct: 864 DTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYD---SGPEG 920
Query: 471 PSLEAPSLWEIPHSAVADAVEPRS---SPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGP 527
+ +P P A A P + P+PP F AP P+ W P+ GP
Sbjct: 921 GAAASP-----PPDAELAACHPAAWSRGPAPPLAFR-GAPGAPL-PWPPA-------TGP 966
Query: 528 GSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPST---REISDLAFGGSQQSPEV 584
GS+ + + + E APG +P SP T + + G S +SP+
Sbjct: 967 GSA-----DGLCTIYETEGPESATPAPGALDPG--PSPGTSGGKAAAGAGAGASSRSPKQ 1019
Query: 585 AAPEPPGSHPVGTLDADKCPEVL 607
A G P+G L A +L
Sbjct: 1020 AR---LGELPLGALQASVVQHLL 1039
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 106 bits (264), Expect = 1e-22
Identities = 209/901 (23%), Positives = 293/901 (32%), Gaps = 153/901 (16%)
Query: 138 PAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVE------- 190
P +P PA P ++ DG S + +P A + EC
Sbjct: 728 PEIPKSVPSPSLPPAGTPPGTKKVDGISHTSAL--------APVASSPKECPTEDSGASA 779
Query: 191 VALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGF 250
A +G + + + P+ + PP G+ P + G+L + P++A+
Sbjct: 780 TASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPI--GNLSSPVSPVEASF-L 836
Query: 251 VQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAK 310
+ +L+ + S ++PA +T P + + A + V PL + + P K
Sbjct: 837 PENSLSFQGSKDSPA-------TTHSPTPPSPKGAPTPSAVT------PLSPKGVTLPPK 883
Query: 311 APRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRA 370
P PS+ ++ PA P S + ++AR T P+ P +
Sbjct: 884 ET-PTPSVVNLPFPKEGPATPAPKQAPALS----MTSSSPKKARATPAPKGIPASPSPKG 938
Query: 371 RSPPFECRIPSEV--PSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSP 428
P PS P+ +P+PP TP GP PSP+ +P
Sbjct: 939 APTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKG------------AP 986
Query: 429 LFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVAD 488
P A+ PA +PSP P++ PS P + A
Sbjct: 987 TPPAATPPSPKGGPA--------TPSPK---------GAPTPPAVTPPS----PKGSPAA 1025
Query: 489 AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP 548
P+ + +PPA P P G SP T P G ++ A T + G P
Sbjct: 1026 TPFPKGASTPPA----ATPPSPKG----SPAATPLPKGAPTTPAATLPSPKG------GP 1071
Query: 549 PTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLG 608
TPS G P P PS + GG AP PP + P P
Sbjct: 1072 ATPSLKGAPTPPAATPPSPK-------GGPATPSPKGAPMPPAATPPSPKGGLATP---- 1120
Query: 609 PGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGS---GLPAPPADPCGEEGGESKT 665
P + A P P P+ AP PA S GL PP P G
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP--PKG-------A 1171
Query: 666 QEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTA 725
PA PP+P + P P PP P P G A
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAA-TPPSPKGGLAT---PSPKGAPTTPA---AT 1224
Query: 726 KPFKRTEIRLPGALALGRRPEVTSRVRARGPG-----GENRDVEAQRLVPDGDGRTSPLG 780
P + + P P T GP G A G T P
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 781 GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL 840
GA + + +P P G P P+ +P P PK P P P A P P
Sbjct: 1285 GAPNPAVVTPPSPKG--GPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS 1342
Query: 841 ALAGRTAPA-QPRAASAPPTDRSPQSPSQGARRQPGAAPL---GKVLVDPESGRYYFVEA 896
T PA P + P T S + P+ P A P G + P R + +
Sbjct: 1343 PKGTPTLPATTPSSKGGPTTPSSKEGPT-----PPAATPSHKGGPAMTPPSPKRGPAIPS 1397
Query: 897 PRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLG-LYPPAYGPI-----PSL 950
P+ DP S + L P +P P G L PPA P+ P+
Sbjct: 1398 PKG-------DPTSPAVIP-LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPAT 1449
Query: 951 SLPPS--PGPQALGSPQLPWVSEAGPLD--GTYYLPVSGTPNPAPPLLLCAPPSSSGPTQ 1006
S P P + G P LP V+ P + + S +P AP P PT
Sbjct: 1450 SAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAP----ATPAPMGAPTL 1505
Query: 1007 P 1007
P
Sbjct: 1506 P 1506
Score = 103 bits (257), Expect = 8e-22
Identities = 246/1049 (23%), Positives = 331/1049 (31%), Gaps = 196/1049 (18%)
Query: 3 TALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPG 62
+ALAP A P++ PT + ++ S G+ SP P V
Sbjct: 758 SALAPVA--SSPKECPTEDSGASATASSKGTLTYLADSPSPLGV---------------- 799
Query: 63 RGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFG 122
SVS Q R GS +GP P L + P +E F
Sbjct: 800 ---------SVSPQTKRPPTKKGS-------AGPDTPIGNLSS-PVSPVEASFLPENSLS 842
Query: 123 CSGADDREAQQQFTEPAFISPLPPGPASPAAV-----------PRQSQVPDGGSRWATYL 171
G+ D A P P P G +P+AV P+++ P L
Sbjct: 843 FQGSKDSPATTHSPTP----PSPKGAPTPSAVTPLSPKGVTLPPKETPTPS-----VVNL 893
Query: 172 ELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPK-RQIELRPRPQSPPR--AAGAPRP 228
GP+ AP Q + + ++P + R P + I P P+ P AA P P
Sbjct: 894 PFPKEGPATPAPKQAPALSMT---SSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSP 950
Query: 229 RLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGST--GRSEPETRETAR 286
+ T S + P A + A AP P +AT S G + P +
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPT 1010
Query: 287 STHVVLEKAKSRPLRV---RDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPL-------G 336
V K P + S P A P P A K AP T G
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 337 PVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPR--SPS 394
P + S+ A P+ P + P PS A P +P+
Sbjct: 1071 PATPSL---KGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPT 1127
Query: 395 PPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSR---R 451
P TP G P P+ T + PA +
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 452 SPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPI 511
+PSP L PS P + A P+ + P+ P AP P
Sbjct: 1188 TPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS--PKGAPTTPA 1245
Query: 512 GTWGPSPQ---ETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTR 568
T PSP+ T P G + A T + G TP G P P + PS +
Sbjct: 1246 AT-PPSPKGGPATPPPKGAPTPPAATPPSLKG------GLATPPHKGAPNPAVVTPPSPK 1298
Query: 569 EISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVR 628
GG SP AP PP + P + P P + A P + P P+
Sbjct: 1299 -------GGPATSPPKGAPTPPAATPPSPKGSPGTP----PPKGAPTPPAVTPPSPKGTP 1347
Query: 629 KLVKTTYA----PGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFI 684
L TT + P P+ +G P PPA +GG PA+ PP+P
Sbjct: 1348 TLPATTPSSKGGPTTPSSKEG---PTPPAATPSHKGG-------PAMTPPSPKRG----- 1392
Query: 685 KDFLPVVPHPY-EPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGR 743
P +P P +P P+ V+ + + A P R P L
Sbjct: 1393 ----PAIPSPKGDPTSPA-------------VIPLSPKKAPATPVTREGAATPSKGDL-T 1434
Query: 744 RPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG-ARSSSQRSPVGPAGVRSPRPG 802
P VT + P ++P GG A SS+ P PA
Sbjct: 1435 PPAVTPVSLKKAPA-----------------TSAPKGGPATPSSKGDPTLPA-------- 1469
Query: 803 SPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRS 862
PSP P PK T+ P A P P AP P + P +
Sbjct: 1470 ----VTPPSPKEPPAPKQVATSSSPKKAPATPAP--------MGAPTLPAVIPSSPKE-V 1516
Query: 863 PQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSS 922
P +PS +RR P AP +L EA P + V P + + P +
Sbjct: 1517 PATPS--SRRDP-IAPTATLLSKKTPATLAPKEALIPPAMTV---PSPKKTPAIPTPKEA 1570
Query: 923 PGPP--HRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYY 980
P P +P A+ Y A P L P P +P P V+ P G
Sbjct: 1571 PATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPAT 1630
Query: 981 LPVSGTPNPAPPLLLCAPPSS--SGPTQP 1007
GTP P PSS PT P
Sbjct: 1631 PAPKGTPTSPP-----VTPSSLKDSPTSP 1654
Score = 94.4 bits (233), Expect = 5e-19
Identities = 243/1046 (23%), Positives = 338/1046 (32%), Gaps = 168/1046 (16%)
Query: 14 PRQLPTAPARRQDS--SGSSGSYYTAPGSPEPPDV--GPDAKGPANWPWVAPGRGAGAQP 69
P++ P PA +Q S +S S A +P P + P KG P P P
Sbjct: 896 PKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATP-----PSP 950
Query: 70 RLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDR 129
+ + + + P + P P GP P P+ P P G + +
Sbjct: 951 KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPP----SPKGGPATPSPK 1006
Query: 130 EAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECV 189
A T PA P P G SPAA P P G S P+G A P
Sbjct: 1007 GAP---TPPAVTPPSPKG--SPAATP----FPKGASTPPAATPPSPKGSPAATP------ 1051
Query: 190 EVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAG 249
L +GA T+P + + P GAP P P A
Sbjct: 1052 ---LPKGAPTTPAATLPSPK-----GGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP 1103
Query: 250 FVQTALARKLSPEAPAPSSATFGSTGR-SEPETRETARSTHVVLEKAKSRPLRVRDNSAP 308
A +P +P AT G + P + + K P +
Sbjct: 1104 MPPAA-----TPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP-----TTPA 1153
Query: 309 AKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQ 368
A P P L A K AP T P S L T P+ AP
Sbjct: 1154 ATPPSPKGGL---ATPPPKGAPTTPAATPPSPKGGLA----------TPSPKGAPTTPAA 1200
Query: 369 RARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSP 428
SP PS P A P+ P TP G PSP+ +P
Sbjct: 1201 TPPSPKGGLATPS--PKGA-----PTTPAATPPSPKGGLATPSPKG------------AP 1241
Query: 429 LFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVAD 488
P A+ PA + +P+PP + PSL+ L PH +
Sbjct: 1242 TTPAATPPSPKGGPATPPP--KGAPTPPAATP----------PSLKG-GLATPPHKGAPN 1288
Query: 489 --AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQE---TWDPMGPGSSIAFTQEAQNGLTQ 543
V P S PA P + P PSP+ T P G + A T + G
Sbjct: 1289 PAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPT 1348
Query: 544 EELAPPTPSAPGTPE-PTEMQSPSTREISDLAFGGSQQSPEV-----AAPEPPG---SHP 594
L TPS+ G P P+ + P+ + GG +P A P P G S
Sbjct: 1349 --LPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406
Query: 595 VGTLDADKCPE--VLGPGEAASGRPRMAIPR--PRDVRKLVKTTYAPGFPAGAQGSGLPA 650
V L K P V G A + + P P ++K T+ G PA G P
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 651 PPA--DPCGEEGGESK---TQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTV 705
PA P +E K T P P PA + + +P P P+ +
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV----PATPSS 1522
Query: 706 ARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEA 765
RD P L + +T P E +P A+ + P+ T + P +
Sbjct: 1523 RRDPIAPTATLLSKKTPATLAP---KEALIPPAMTVPS-PKKTPAI----PTPKEAPATP 1574
Query: 766 QRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG---SPQMQASPSPG---IAPKPK 819
+P + S + + P V SP P +P PSP P PK
Sbjct: 1575 SSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPK 1634
Query: 820 TPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPL 879
PT+P + P P ++ + P+A+ P + P + L
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA-------------L 1681
Query: 880 GKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGL 939
+VLV P + AP + P++ + PP P P + + L +
Sbjct: 1682 KEVLVAPAPESTPIITAPTRK------GPQT-KKSSATSPPICPDPSAKNGSKGPLST-V 1733
Query: 940 YPPAYGPIPSLSLPPSPGPQALGSPQLPWV----SEAGPLDGTYYLPVSGTPN------- 988
P P+ S + G A SP+ P + PL + V P
Sbjct: 1734 APAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAA 1793
Query: 989 PAPPLLLCAPPSSSGPTQPGKGSLFP 1014
P+PP+ L PS PT P K P
Sbjct: 1794 PSPPVSLPLAPSPV-PTLPPKQQFLP 1818
Score = 92.8 bits (229), Expect = 1e-18
Identities = 221/970 (22%), Positives = 312/970 (32%), Gaps = 189/970 (19%)
Query: 8 PALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGA 67
PA P P+ PT PA S + + G+P PP P + P P +GA
Sbjct: 954 PATPS-PKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS--PKGGPATPSPKGAPT 1010
Query: 68 QPRLSVSAQNSRQRHGPGSGFPRGPGSGPR--PPQPQ----LRTLPSGEMEVIFGVGPLF 121
P ++ + P FP+G + P PP P+ LP G P
Sbjct: 1011 PPAVTPPSPKGSPAATP---FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS- 1066
Query: 122 GCSGADDREAQQQFTEPAFISPLPPG----------PASPAAVPRQSQVPDGGSRWATYL 171
G + T PA P P G P PAA P P GG L
Sbjct: 1067 PKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPS---PKGG------L 1117
Query: 172 ELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQS-----PPR----- 221
P +P PA + + G A P+ P P P+ PP+
Sbjct: 1118 ATPPHKGAPTTPA---ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174
Query: 222 -AAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGST--GRSE 278
AA P P+ L T S + A + LA AP +AT S G +
Sbjct: 1175 PAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLAT 1234
Query: 279 PETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRER-AIRRDKPAPGTEPLGP 337
P + + K P AP PSL+ A K AP + P
Sbjct: 1235 PSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTP 1294
Query: 338 VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPR 397
S + T P+ AP A +PP P P + +P+PP
Sbjct: 1295 PSP----------KGGPATSPPKGAP---TPPAATPPSPKGSPGTPPPKG----APTPPA 1337
Query: 398 QTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPI 457
TP P P+ S TT P A++ PA+ +R P+ P
Sbjct: 1338 VTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPS 1397
Query: 458 LSQWNQCVAGERSPSLEAPSLWEIPHSAVAD---AVEPRSSPSPPAFFPW---EAPDRPI 511
SP++ S + P + V A + +PPA P +AP
Sbjct: 1398 PK------GDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSA 1451
Query: 512 GTWGPS-PQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREI 570
GP+ P DP P + PP+P P P+ S +
Sbjct: 1452 PKGGPATPSSKGDPTLPA-----------------VTPPSPKEPPAPKQVATSSSPKKAP 1494
Query: 571 SDLAFGGSQQSPEVAAPEP------PGSH-----PVGTLDADKCPEVLGPGEAASGRPRM 619
+ A G+ P V P P S P TL + K P L P EA P M
Sbjct: 1495 ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIP-PAM 1553
Query: 620 AIPRPRDVRKLVKTTYAPGFPAGAQGS-----------GLPAPPA---DPCGEEGGESKT 665
+P P+ + AP P+ + S G P+P P +
Sbjct: 1554 TVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEA 1613
Query: 666 QEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSF--DTVARDASQPNGVLRRRAENS 723
PPA+ PP+P + P P P PS D+ AS + + S
Sbjct: 1614 PTPPAVTPPSPEKGPATPAPKGTPTSP----PVTPSSLKDSPTSPASVTCKMGATVPQAS 1669
Query: 724 TAKPFKRTEIRLPGALALGRRPEVTSRVRA---RGPGGENRDVEAQRLVPDG---DGRTS 777
P K+ L L + PE T + A +GP + + + PD +G
Sbjct: 1670 KGLPAKKGPTALKEVL-VAPAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 778 PL--------------------GGARSSSQRSPVGPAGVRS-------------PRPGSP 804
PL G S S + P+ P ++ P+P S
Sbjct: 1729 PLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESA 1788
Query: 805 QMQASPSPGI------------APKPKTPPTAPEPAAAVQAPLPREPLALAGR-----TA 847
+ A+PSP + PK + P++P + P +PLA A
Sbjct: 1789 SVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSP----GLVLESPSKPLAPADEDELLPLI 1844
Query: 848 PAQPRAASAP 857
P +P + P
Sbjct: 1845 PPEPISGGVP 1854
Score = 77.8 bits (190), Expect = 5e-14
Identities = 135/537 (25%), Positives = 178/537 (33%), Gaps = 118/537 (21%)
Query: 516 PSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAF 575
PSPQ T P+ +++ E + L PP + PGT + + S A
Sbjct: 712 PSPQNTCAPL---ATLVLAPEIPKSVPSPSL-PPAGTPPGTKKVDGISHTS-------AL 760
Query: 576 GGSQQSPEVAAPEPPGSHPV----GTLD--ADKCPEVLG----------PGEAASGRPRM 619
SP+ E G+ GTL AD P LG P + S P
Sbjct: 761 APVASSPKECPTEDSGASATASSKGTLTYLADS-PSPLGVSVSPQTKRPPTKKGSAGPDT 819
Query: 620 AIPRPRDVRKLVKTTYAPGFPAGAQGS-GLPAPPADPCGEEGGESKTQEPPALGPPAPAH 678
I V+ ++ P QGS PA P P G P P+
Sbjct: 820 PIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT----------PPSPKGAPTPSA 869
Query: 679 YTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRA---ENSTAKPFKRTEIRL 735
T + K V P E P PS + P ++A +++ P K
Sbjct: 870 VTPLSPKG---VTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926
Query: 736 PGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQR-SPVGPA 794
P + P+ A P SP GG + S + +P PA
Sbjct: 927 PKGIPASPSPKGAPTPPAATP-------------------PSPKGGPATPSPKWAPTPPA 967
Query: 795 GVR-SPR--PGSPQMQASPSPGIA--PKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPA 849
SP+ P +P + +P+P A P PK P P P A P P A
Sbjct: 968 ATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATP 1027
Query: 850 QPRAASAPPTDRSPQSPSQGARRQPGAAPLGK--------VLVDPESGRYYFVEAPRQPR 901
P+ AS PP +P SP + P A PL K L P+ G P P
Sbjct: 1028 FPKGASTPPA-ATPPSP----KGSPAATPLPKGAPTTPAATLPSPKGG-------PATPS 1075
Query: 902 LRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSP----- 956
L+ P + PPS G P TP P P+P + PPSP
Sbjct: 1076 LKGAPTPPAA------TPPSPKGGP---ATP--------SPKGAPMPPAATPPSPKGGLA 1118
Query: 957 GPQALGSPQLPWVSEAGPLDGTYYLPVSGTPN------PAPPLLLCAPPSSSGPTQP 1007
P G+P P + P G P G P P+P L PP PT P
Sbjct: 1119 TPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTP 1175
Score = 63.2 bits (152), Expect = 1e-09
Identities = 204/984 (20%), Positives = 326/984 (33%), Gaps = 160/984 (16%)
Query: 136 TEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEE 195
T PA LP A A +P S + S A + P P P +PA +C A +
Sbjct: 8 TVPATEQELPQPQAETAVLPMSSAL----SVTAALGQPGPTLPPPCSPAPQQCPLSAANQ 63
Query: 196 GAAPARPRTVPKRQIELRPRPQSPPRAA----GAPRPRLLLRTGSLDESLGPLQAAAGFV 251
+ P T+ +E+ P PQS A AP L + + P A
Sbjct: 64 ASPFPSPSTIASTPLEV-PFPQSSSGTALPLGTAPEAPTFL-PNLIGPPISPAALALASP 121
Query: 252 QTALARKLSPEAPAP------------SSATFGSTGRSEPETRETARSTHVVLEKAKSRP 299
A K +P + AP S+ F + P + A S V+ A P
Sbjct: 122 MIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSAPIAP 181
Query: 300 LRVRDN--SAPAKA-PRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKT 356
+ N P++ P P + I P P+ + S + +
Sbjct: 182 SEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAI 241
Query: 357 RFPREAPDRTVQRAR-SP--PFECRIPSEV-PSRAVRPRSPSPPRQTPNGAVRGPRCPSP 412
P + D T+ SP P + V P A+ + S P T + GP P
Sbjct: 242 ASP-QVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPD 300
Query: 413 ------QNLSPWDRTTR---RVSSPLFPEASSEWENQNPAVEETV------SRRSPSPPI 457
+L+P +++ ++ P A S+ + +V+ + S+RS PP+
Sbjct: 301 FPISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPL 360
Query: 458 LSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP--------------------RSSPS 497
S+ A + + APS+ + P + + P +SSP+
Sbjct: 361 PSRNEVVPATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPN 420
Query: 498 PPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPT----PSA 553
+P A P+ + G +P +P ++ T E ++ + P P++
Sbjct: 421 ATYHYPLVA-QMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTS 479
Query: 554 PGT--PEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTL-------DADKCP 604
P P + PST+ + L SP + PE + P L D P
Sbjct: 480 PAALVMAPVAPKEPSTQVATTLRI---PVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVP 536
Query: 605 EVLGPGEAASGRPRMAIPRPRDVRKLVKTT--YAPGFPAGAQGSGLPAPPADPCGEEGGE 662
L + + + + V LV+ +P F + + +P P ++
Sbjct: 537 ASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKS-- 594
Query: 663 SKTQEPPALGPPAPAHYTSVFIKDFLPVVP-HPYEPPE------------PSFDTVARDA 709
EP +G PA + + + + V+ Y P+ P+ ++
Sbjct: 595 --LGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLES 652
Query: 710 SQPNGVLRRRAENS-----TAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVE 764
+ P GV A+ + TA PF L G ++L +
Sbjct: 653 ADPAGVAPTTAKGTSTYTTTASPF------LEGTVSLAPK-------------------- 686
Query: 765 AQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA 824
V +G T PL ++S+ PV P+ + P + + A P P P PP
Sbjct: 687 -NHPVKEGTLTTLPL--VPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAG 743
Query: 825 PEPAA----AVQAPLPREPLALAGRTAPAQPRAASAPPTDR--------SPQSPSQGARR 872
P + P+A + + P + ASA + + SP
Sbjct: 744 TPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSP 803
Query: 873 QPGAAPLGKVLVDPE------SGRYYFVEAPRQPRLRVLF--DPESGQYVEVLLPPSSPG 924
Q P K P+ S VEA P + F +S PPS G
Sbjct: 804 QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKG 863
Query: 925 -PPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPV 983
P TPL+ PP P PS+ P P P P +A L T P
Sbjct: 864 APTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKE----GPATPAPKQAPALSMTSSSPK 919
Query: 984 SGTPNPAPPLLLCAPPSSSGPTQP 1007
PAP + +P PT P
Sbjct: 920 KARATPAPKGIPASPSPKGAPTPP 943
Score = 39.7 bits (91), Expect = 0.015
Identities = 49/219 (22%), Positives = 76/219 (34%), Gaps = 18/219 (8%)
Query: 801 PGSPQMQASPSPG-IAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPT 859
P P+ + P + P PK P+ P + V P A Q AS P T
Sbjct: 181 PSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTV-------PYHCVTPMASIQSGVASLPQT 233
Query: 860 DRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLP 919
+P + A Q + VL+ P++ ++ P P + +S V
Sbjct: 234 --TPTTTLAIASPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQK 291
Query: 920 PSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTY 979
+ P P P++LG L P S+ L GP AL P + +S G
Sbjct: 292 TAGPNTPPDF--PISLGSHLAPLHQSSFGSVQLLGQTGPSALSDPTVKTISVDHSSTGAS 349
Query: 980 Y------LPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSL 1012
Y +P + N P + A P + G ++
Sbjct: 350 YPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTI 388
Score = 33.1 bits (74), Expect = 1.4
Identities = 54/225 (24%), Positives = 72/225 (32%), Gaps = 19/225 (8%)
Query: 756 PGGENRDVEA-QRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGI 814
PG V A ++ +P T+ L + + S + +G G P P SP Q P
Sbjct: 2 PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61
Query: 815 APKPKTPPTAPEPAAAVQAPLPREP--LALAGRTAPAQPRAASAPPTDRSPQSPSQGARR 872
P + + ++ P P+ AL TAP P P P SP+ A
Sbjct: 62 NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAP--TFLPNLIGPPISPAALALA 119
Query: 873 QPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTP 932
P AP K P S P V P S Q P PP
Sbjct: 120 SPMIAPTLK--GTPSSS---------APLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 933 LALGLGLYPPAYGPIPSLSLPPSPG---PQALGSPQLPWVSEAGP 974
+ L P P +L P P G+P P + P
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVPNPKGTPSPPCIVSTVP 213
Score = 32.7 bits (73), Expect = 1.8
Identities = 71/323 (21%), Positives = 108/323 (33%), Gaps = 38/323 (11%)
Query: 6 APPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGS--PEPPDVGPDAKGPANWPWVAPGR 63
A PA G P P P+ +DS S S G+ P+ P KGP V
Sbjct: 1629 ATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 64 GAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGC 123
+ P ++ + Q + P P P P + G + + PL
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSP------PICPDPSAKNGSKGPLSTV-APAPLLPV 1741
Query: 124 SGADDREAQQQFTEPAFISPLPP------GPASPAAVPRQSQVPDGGSRWA-----TYLE 172
+ A+ + + PL P P + AA + P+ S A L
Sbjct: 1742 QKDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLP 1801
Query: 173 LRPRGPSPAAPAQFECVE----VALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRP 228
L P P P P + + + + LE +P++P P + EL P P + G P
Sbjct: 1802 LAP-SPVPTLPPKQQFLPSSPGLVLE---SPSKP-LAPADEDELLPLIPPEPISGGVPFQ 1856
Query: 229 RLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARST 288
+L+ P +AG + K S T + S PE E ST
Sbjct: 1857 SVLVNM--------PTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELEE-QDST 1907
Query: 289 HVVLEKAKSRPLRVRDNSAPAKA 311
++A+ D +KA
Sbjct: 1908 QATTQQAQLAAAAEIDEEPVSKA 1930
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 95.5 bits (236), Expect = 2e-19
Identities = 194/773 (25%), Positives = 272/773 (35%), Gaps = 146/773 (18%)
Query: 259 LSPEAPAPSSATFGSTGRS----EPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRP 314
+ P+ P P G++ EP+ +L + PL +P P P
Sbjct: 404 MQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPP-P 462
Query: 315 WPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPP 374
S R P P P P+ ++ L ++E+ + P E+P SPP
Sbjct: 463 EAS-------RLSPPPEELPASPLPEALHLS--RPLEESPLSPPPEESP-------LSPP 506
Query: 375 FECRIPSEVPSRAVRPRSPSPPRQTP-NGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEA 433
P P + SPP ++P + A+ P P P+ SP SPL P
Sbjct: 507 -----PESSPFSPLEESPLSPPEESPPSPALETPLSPPPE-ASPLSPPFEE--SPLSPPP 558
Query: 434 SSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPR 493
+ P SR SP P SP EA L+ P + P
Sbjct: 559 EELPTSPPPEA----SRLSPPPEESPMSPPPEESPMSPPPEASRLFP-PFEESPLSPPPE 613
Query: 494 SSP-SPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPS 552
SP SPP +P P P+E+ PM P ++ L+PP
Sbjct: 614 ESPLSPPPEASRLSPPPEDSPMSPPPEES--PMSPPPEVSRLSPLP---VVSRLSPPPEE 668
Query: 553 APGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPE-----PPGSHPVGTLDADKCPEVL 607
+P +P P E + E S L+ + SP PE PP + +L ++ P +
Sbjct: 669 SPLSPPPEESPTSPPPEASRLS-PPPEDSPTSPPPEDSPASPPPEDSLMSLPLEESPLLP 727
Query: 608 GPGEAA----SGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPC----GEE 659
P E S P ++ PRP + L P A+ L P +PC EE
Sbjct: 728 LPEEPQLCPRSEGPHLS-PRPEEPH-LSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEE 785
Query: 660 GGESKTQEPPALGP-PAPAHYTSVFIKDFLPVVPH-PYEPPEPSFDTVARDASQPNGVLR 717
S E P L P P H + + L VP P P+P ++ + +P L
Sbjct: 786 PHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEP--CLS 843
Query: 718 RRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTS 777
R E S P E+ P L RPE + P E E P G+ S
Sbjct: 844 PRPEESHLSP----ELEKP---PLSPRPEKPPEEPGQCPAPE----ELPLFPPPGEPSLS 892
Query: 778 PLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAP--EPAAAVQAPL 835
PL G + S+ PG P + +P P+ P +P EP+ + Q +
Sbjct: 893 PLLGEPALSE-------------PGEPPL--------SPLPEELPLSPSGEPSLSPQL-M 930
Query: 836 PREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVE 895
P +PL PP P SP A P +PLG++ Y F
Sbjct: 931 PPDPL----------------PP----PLSPIITAAAPPALSPLGEL-------EYPFGA 963
Query: 896 APRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPS 955
DPES +L P SP P P P+P + LPPS
Sbjct: 964 KGDS-------DPESPLAAPILETPISPPPEANCTDP------------EPVPPMILPPS 1004
Query: 956 PG-PQALGSPQL--PWVSEAGPLDGTYYLPVSGTPNP-APPLLLCAPPSSSGP 1004
PG P SP L P + PL +P + P+ +PP L + PS P
Sbjct: 1005 PGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPLSP 1057
Score = 69.3 bits (168), Expect = 2e-11
Identities = 143/572 (25%), Positives = 200/572 (34%), Gaps = 72/572 (12%)
Query: 471 PSLEAPSLWEIPHSAVADAVEPRSSP-SPPAFFPWEAPDRP---IGTWGPSPQETWDPMG 526
P LEAP E+P P SP SPP P E+P P P P+E
Sbjct: 428 PQLEAPLNEEMPLLP-----PPEESPLSPP---PEESPTSPPPEASRLSPPPEEL----- 474
Query: 527 PGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAA 586
P S + L + L+PP +P +P P +S + + ++SP A
Sbjct: 475 PASPLPEALHLSRPLEESPLSPPPEESPLSPPP---ESSPFSPLEESPLSPPEESPPSPA 531
Query: 587 PEPPGSHPVGTLDA----DKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAG 642
E P S P ++ P P E + P P R +P P
Sbjct: 532 LETPLSPPPEASPLSPPFEESPLSPPPEELPTSPP------PEASRLSPPPEESPMSPPP 585
Query: 643 AQGSGLPAPPAD---PCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPE 699
+ P P A P EE S E L PP A S +D P+ P P E P
Sbjct: 586 EESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDS-PMSPPPEESPM 644
Query: 700 PSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGE 759
V+R + P + + P + + + P + P SR+ P E
Sbjct: 645 SPPPEVSRLSPLP-------VVSRLSPPPEESPLSPPPEESPTSPPPEASRL---SPPPE 694
Query: 760 NRDVEAQRLVPDGDGRTSPLGGARSSS---QRSPVGPAGVRS---PRPGSPQMQASPS-P 812
+ P D SP S + SP+ P PR P + P P
Sbjct: 695 DSPTSP----PPEDSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEP 750
Query: 813 GIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGAR- 871
++P+P+ P +P+ +P P EP A P A P P+ +
Sbjct: 751 HLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQT 810
Query: 872 RQPGAAPL-GKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSP----GPP 926
+P +P+ + + P+ + +P L ES E+ PP SP P
Sbjct: 811 EEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPR-PEESHLSPELEKPPLSPRPEKPPE 869
Query: 927 HRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGT 986
P L L+PP P SL P G AL P P +S PL L SG
Sbjct: 870 EPGQCPAPEELPLFPPPGEP----SLSPLLGEPALSEPGEPPLS---PLPEELPLSPSGE 922
Query: 987 PNPAPPLL---LCAPPSSSGPTQPGKGSLFPL 1015
P+ +P L+ PP S T +L PL
Sbjct: 923 PSLSPQLMPPDPLPPPLSPIITAAAPPALSPL 954
Score = 65.9 bits (159), Expect = 2e-10
Identities = 101/396 (25%), Positives = 133/396 (33%), Gaps = 118/396 (29%)
Query: 659 EGGESKTQEPPAL-----GPPAPAHYTSVFIKD--------------------------- 686
E G++ T EP AL G P H TS+ K+
Sbjct: 376 EPGDTPTDEPDALYVACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAPLN 435
Query: 687 -FLPVVPHPYE-----PPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALA 740
+P++P P E PPE S + +AS+ L E A P LP AL
Sbjct: 436 EEMPLLPPPEESPLSPPPEESPTSPPPEASR----LSPPPEELPASP-------LPEALH 484
Query: 741 LGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPR 800
L +R +E L P + SPL SS SP+ + + P
Sbjct: 485 L------------------SRPLEESPLSPPPE--ESPLSPPPESSPFSPLEESPLSPPE 524
Query: 801 --PGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPP 858
P SP ++ SP P +PP P + LP P A R +P + +PP
Sbjct: 525 ESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPP 584
Query: 859 TDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYY--FVEAPRQPRLRVLFDPESGQYVEV 916
+ SP SP PE+ R + F E+P P PE
Sbjct: 585 PEESPMSP------------------PPEASRLFPPFEESPLSP------PPEES----- 615
Query: 917 LLPPSSPGPPHRVYTPLALGLGLYPPAYGPI--PSLSLPPSPGPQALGSPQLPWVSEAGP 974
P SP P +P PP P+ P P SP P+ LP VS P
Sbjct: 616 ---PLSPPPEASRLSP--------PPEDSPMSPPPEESPMSPPPEVSRLSPLPVVSRLSP 664
Query: 975 LDGTYYL---PVSGTPNPAPPLLLCAPPSSSGPTQP 1007
L P +P P +PP PT P
Sbjct: 665 PPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSP 700
Score = 60.5 bits (145), Expect = 8e-09
Identities = 221/944 (23%), Positives = 298/944 (31%), Gaps = 205/944 (21%)
Query: 6 APPALP------GIPRQLPTAPARRQDSSGSSGSYYTA-PGSPEPPDVGPDAKGPANWPW 58
APP P G P Q P A + +G G ++T PG+P PD P+
Sbjct: 2192 APPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPD-------PF 2244
Query: 59 VAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGP---RPPQPQLRTLPSGEMEVIF 115
+ P S N PG G G S P PP + R + E +
Sbjct: 2245 LKP---------RCPSLDNLAVPESPGVG--GGKASEPLLSPPPFGESRKALEVKKEELG 2293
Query: 116 GVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRP 175
P +G ++ T + P PR SQV + L LRP
Sbjct: 2294 ASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQV----EPQSPGLGLRP 2349
Query: 176 RGPSPAAPAQFECVEVALEEGAAPARPR----------TVPKRQIELRPRPQSPPRAAGA 225
+ P PA + AP+ P T P Q L PRPQ PP +
Sbjct: 2350 QEPPPA-------------QALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCC 2396
Query: 226 PRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEA--PAPSSATFGSTGRSEPETRE 283
P L + Q+ + R LS EA P+P + F S +P +R
Sbjct: 2397 ALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQS---PDPYSRP 2453
Query: 284 TARSTHVVLEKAKSRPLRVRDNSAPA-KAPRPWPSLRERAIRRDKPA---------PGTE 333
+R + RD AP K PRP P E A + A P
Sbjct: 2454 PSRP-------------QSRDPFAPLHKPPRPQPP--EVAFKAGSLAHTSLGAGGFPAAL 2498
Query: 334 PLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSP 393
P GP + K+ + F R +P P P V +++P P
Sbjct: 2499 PAGPAG-----ELHAKVPSGQPPNFVR-SPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVP 2552
Query: 394 SPPRQTPNGAVR----GPRCPSPQ--NLSPWDRTTRRVSSPLFPEASSEWENQNPAVEET 447
P P+G GP PQ N + SPL P + S E+ +
Sbjct: 2553 QPGLPPPHGINSHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRP 2612
Query: 448 VSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP 507
S P P SL S S + VE R P
Sbjct: 2613 PSVLPPPAP-------------DGSLPYLSHGASQRSGITSPVEKREDPGTGMGSSLATA 2659
Query: 508 DRPIGTWGP-------SPQETWDPMGPGSSIAFTQEAQ-NGLTQE-ELAPPTPSAPGTPE 558
+ P GT P + E + Q+ Q N L QE E A A G P
Sbjct: 2660 ELP-GTQDPGMSGLSQTELEKQRQRQRLRELLIRQQIQRNTLRQEKETAAAAAGAVGPPG 2718
Query: 559 P--TEMQSPSTREIS--DLAFGGSQ-QSPEVAAPEPPGSHPVGTLDADKCPEVLGPG--- 610
E SP+ ++S F G+Q +S V P S P +LGPG
Sbjct: 2719 SWGAEPSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGP-----------ILGPGSFP 2767
Query: 611 --EAASGRPRMAIPRPRDV--RKLVKTTYAPGFPAGAQG--SGLPAPPADPCGEEGGESK 664
+ S P A P DV R+LV G+Q P P + P ++ +
Sbjct: 2768 SDDRLSRPPPPATPSSMDVNSRQLV---------GGSQAFYQRAPYPGSLPLQQQQQQLW 2818
Query: 665 TQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENST 724
Q+ TS+ F AR S P L R+A S
Sbjct: 2819 QQQQATAA-------TSM------------------RFAMSARFPSTPGPELGRQALGS- 2852
Query: 725 AKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARS 784
P RLPG GP G + +E + V G G +
Sbjct: 2853 --PLAGISTRLPG-----------PGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQG 2899
Query: 785 SSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAG 844
QR P R ++ G+ P+ + P APE ++ P P G
Sbjct: 2900 PPQRPRFYPVSEDPHRLAPEGLRGLAVSGLPPQKPSAPPAPELNNSLH-PTPH----TKG 2954
Query: 845 RTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKV-LVDPE 887
T P + PP S ++ R P A GK+ DPE
Sbjct: 2955 PTLPTGLELVNRPP------SSTELGRPNPLALEAGKLPCEDPE 2992
Score = 59.7 bits (143), Expect = 1e-08
Identities = 174/779 (22%), Positives = 263/779 (33%), Gaps = 130/779 (16%)
Query: 177 GPSPAAPAQFECVEVALEEGAA---------------PARPRTVPKRQIELRPRPQSPPR 221
GP P P + AL G P RP +P +L Q PP
Sbjct: 4280 GPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQLPPT 4339
Query: 222 AAGAPRPRLLLRTGSLDESLGPLQ-AAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPE 280
G P+P+ +L+ G + AAA T ++ L P P + A E
Sbjct: 4340 HPGTPKPQ----GPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLA----------E 4385
Query: 281 TRETARSTHVV--LEKAKSRPLRVRDNSAPAKAPRPWP-SLRERAIRRDKPAPGTEPLGP 337
T++ +S+ V L++ + + + + PR P +L ++++R+ EP+G
Sbjct: 4386 TQKPEQSSLVPGHLDQVNGQVVPEASQLSIKQEPREEPCALGAQSVKREANG---EPIGA 4442
Query: 338 VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRAR---SPPFECRIPSEVPSR--AVRPRS 392
+S L EA + + VQ + S I + S+ + +
Sbjct: 4443 PGTSNHLLLAGPRSEAGHLLLQKLLRAKNVQLSTGRGSEGLRAEINGHIDSKLAGLEQKL 4502
Query: 393 PSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRS 452
P + A R P P P+ + + R VSS E+ A E + +
Sbjct: 4503 QGTPSNKEDAAARKPLTPKPKRVQK--ASDRLVSS----RKKLRKEDGVRASEALLKQLK 4556
Query: 453 PSPPILSQWNQCVAGERSPSLEAPSLWEIP---HSAVADAVEPRSSPSPPAFFPWEAPDR 509
+L + S L AP P S + A + P+ P ++
Sbjct: 4557 QELSLLPLTEPAITANFS--LFAPFGSGCPVNGQSQLRGAFGSGALPTGPDYYSQLLTKN 4614
Query: 510 PIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTRE 569
+ P+P + P P S Q+ NG+T E P + +E T E
Sbjct: 4615 NLSN-PPTPPSSLPPTPPPS---VQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSE 4670
Query: 570 ISDLAFGGSQQSP------EVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPR 623
+ L + +P +V S ++ PE + GE A P + R
Sbjct: 4671 VKSLDLLAALPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESI-LGEEAPRFPHLGSGR 4729
Query: 624 PRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVF 683
+ + +P P + S P P G G E + P SV
Sbjct: 4730 WEQEDRAL----SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVM 4785
Query: 684 IKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALA-LG 742
+ A A NGV+ AE + K E+ P + A G
Sbjct: 4786 LT------------------VSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAG 4827
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSP---------LGGARSSSQRSPVGP 793
P+ + A GPGG+ + +E + PD T P L G SQ +
Sbjct: 4828 TEPK---KGEAEGPGGKEKGLEGKS--PD----TGPDWLKQFDAVLPGYTLKSQLDILSL 4878
Query: 794 AGVRSPRPGSPQMQASPSPGI---------APKPKTPPTAPEPAAAVQAPLPREPLALAG 844
SP P P Q S + + AP P+ P P P A A P EPL
Sbjct: 4879 LKQESPAP-EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELP 4937
Query: 845 RTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLR 903
A+P S P SP+S AR +P A P PE G E R PRL+
Sbjct: 4938 TEPLAEPPVPSPLPLASSPES----ARPKPRARP-------PEEG-----EDSRPPRLK 4980
Score = 53.9 bits (128), Expect = 7e-07
Identities = 75/287 (26%), Positives = 95/287 (33%), Gaps = 75/287 (26%)
Query: 789 SPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA---PEPAAAVQAPLPREPLALAGR 845
SP PAG+ + G P G P P +P P Q P ++P LA
Sbjct: 2128 SPTTPAGLSTSADGF----LKPPAGSVPGPDSPGELFLKLPPQVPAQVP-SQDPFGLAP- 2181
Query: 846 TAPAQPRAASAPPT--------DRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAP 897
P +PR +APPT Q P GA +PGA G+ P + P
Sbjct: 2182 AYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTP 2241
Query: 898 ------RQPRLRVLFDPES-----GQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGP 946
R P L L PES G+ E LL P G + LG P+YGP
Sbjct: 2242 DPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYGP 2301
Query: 947 IPSLSLPPSPG------------PQALGSPQLPWVSEAGPLD------------------ 976
P+L SP P +P P S+ P
Sbjct: 2302 -PNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPPPAQALAP 2360
Query: 977 -----------GTY-----YLPVSGTPNPAPPLLLCAPPSSSGPTQP 1007
G+Y P++ P P PP CA P S P+ P
Sbjct: 2361 SPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRSLPSDP 2407
Score = 52.0 bits (123), Expect = 3e-06
Identities = 131/540 (24%), Positives = 173/540 (32%), Gaps = 119/540 (22%)
Query: 546 LAPPTPSAPGTPEPTEM------QSPSTREISD-----LAFGGSQQSPEVAAPEPPGSHP 594
L PP S PG P E+ Q P+ D A+ + P PP P
Sbjct: 2143 LKPPAGSVPGPDSPGELFLKLPPQVPAQVPSQDPFGLAPAYPLEPRFPTAPPTYPPYPSP 2202
Query: 595 VGT------LDADKCPEVLGPGE---AASGRPRMAIPRPRDVRK-------LVKTTYAPG 638
G L A P PGE G PR P K + +PG
Sbjct: 2203 TGAPAQPPMLGASSRPGAGQPGEFHTTPPGTPRHQPSTPDPFLKPRCPSLDNLAVPESPG 2262
Query: 639 FPAGAQGSGLPAPPADPCGEE-----------GGESKTQEPPALG----PPAPAHYTSVF 683
G L +PP P GE G S + PP LG P + H +
Sbjct: 2263 VGGGKASEPLLSPP--PFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLE 2320
Query: 684 IKD----FLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGAL 739
+K P+ P + S R P A+ P +I PG+
Sbjct: 2321 LKTPDVFKAPLTPRASQVEPQSPGLGLRPQEPP------PAQALAPSPPSHPDIFRPGSY 2374
Query: 740 A-LGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGP----A 794
+P +T R + P E+ R +P P SS +SP+ P A
Sbjct: 2375 TDPYAQPPLTP--RPQPPPPESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSA 2432
Query: 795 GVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREP---------LALAGR 845
P P +P+ Q SP +P + P + +P A + P +P LA
Sbjct: 2433 EAFCPSPVTPRFQ---SPDPYSRPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSL 2489
Query: 846 TAPAQPRAASAPPTD----RSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPR 901
A P A A P + P R PG G + P R+ F +A +P
Sbjct: 2490 GAGGFPAALPAGPAGELHAKVPSGQPPNFVRSPGT---GAFVGTPSPMRFTFPQAVGEPS 2546
Query: 902 LRVLFDPESGQYVEVLLPPSSPG--PPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQ 959
L+ P PG PPH + + +GP P+L P S
Sbjct: 2547 LKP--------------PVPQPGLPPPHGINS-----------HFGPGPTLGKPQSTNYT 2581
Query: 960 ALGSPQLPWVSEAGPLDG----TYYL----PVSGTPNPAP----PLLLCAPPSSSGPTQP 1007
P S GP G +Y L P S P PAP P L SG T P
Sbjct: 2582 VATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGITSP 2641
Score = 51.6 bits (122), Expect = 4e-06
Identities = 82/352 (23%), Positives = 122/352 (34%), Gaps = 47/352 (13%)
Query: 547 APPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEP--PG-----SHPVGTLD 599
+PP P T EP + +A G + V + +P PG + P+G
Sbjct: 373 SPPEPGDTPTDEPDALY---------VACQGQPKGGHVTSMQPKEPGPLQCEAKPLGKAG 423
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAP---PADPC 656
P++ EA +P P + +P P P P PA P
Sbjct: 424 VQLEPQL----EAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPL 479
Query: 657 GEEGGESKTQEPPALGPP------APAHYTSVFIK-DFLPVVPHPYEPPEPSFDTVARDA 709
E S+ E L PP +P +S F + P+ P PP P+ +T
Sbjct: 480 PEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPP 539
Query: 710 SQPNGVLRRRAENSTAKPFKRTEIRLPG-ALALGRRPEVTSRVRARGPGGENRDVEAQRL 768
+ + + E+ + P + P A L PE + + EA RL
Sbjct: 540 PEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599
Query: 769 VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPG-IAPKPKTPPTAPEP 827
P + SPL S SP A SP P M P ++P P+ +P P
Sbjct: 600 FPPFE--ESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPLP 657
Query: 828 AAAVQAPLPRE-------------PLALAGRTAPAQPRAASAPPTDRSPQSP 866
+ +P P E P A R +P + ++PP + SP SP
Sbjct: 658 VVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPASP 709
Score = 50.8 bits (120), Expect = 6e-06
Identities = 196/912 (21%), Positives = 280/912 (30%), Gaps = 145/912 (15%)
Query: 8 PALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGA 67
P LP P + P +P + S +S + SP PP+ P + P P +
Sbjct: 439 PLLPP-PEESPLSPP--PEESPTSPPPEASRLSP-PPEELPASPLPEALHLSRPLEESPL 494
Query: 68 QPRLSVSAQNSRQRHGPGSGFPRGPGSGPR--PPQPQLRTLPSGEMEVIFGVGPLFGCSG 125
P S + P S P S P PP P L T S E PL
Sbjct: 495 SPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSPPPEA----SPL----- 545
Query: 126 ADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQ 185
F E P P SP + P S + E P P P A
Sbjct: 546 ------SPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASRL 599
Query: 186 FECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQ 245
F E + P + P L P P+ P +P P + + P
Sbjct: 600 FPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPM---SPPPE--------ESPMSPPP 648
Query: 246 AAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDN 305
+ + +LSP PE E S P
Sbjct: 649 EVSRLSPLPVVSRLSP----------------PPE------------ESPLSPPPEESPT 680
Query: 306 SAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDR 365
S P +A R P + P P P P + ++E+ P E +
Sbjct: 681 SPPPEASRLSPPPEDSP---TSPPPEDSPASPPPEDSLMSL--PLEESPLLPLPEE--PQ 733
Query: 366 TVQRARSPPFECRIPSEVPSRAVRPRSP--SPPRQTPNGAVRGPR-----CPSPQNLSPW 418
R+ P R E P + RP P SP + P+ + + P +LSP
Sbjct: 734 LCPRSEGPHLSPR--PEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQ 791
Query: 419 DRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSL 478
P E + +P EE P P LS Q SP E P L
Sbjct: 792 AEGPHLSPQP-------EELHLSPQTEEPHLSPVPEEPCLSP--QPEESHLSPQSEEPCL 842
Query: 479 WEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQ 538
P + + P P + P + P+ P P + P G S
Sbjct: 843 SPRPEES---HLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLFPPPGEPS--------- 890
Query: 539 NGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPE--PPGSHPVG 596
L P S PG P SP E+ G SP++ P+ PP P+
Sbjct: 891 ---LSPLLGEPALSEPGEPP----LSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Query: 597 TLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSG------LPA 650
T A LG E G + P +++T +P A LP
Sbjct: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVPPMILPP 1003
Query: 651 PPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDAS 710
P P G P L P P + + +P P + P+
Sbjct: 1004 SPGSPVGPAS--------PILMEPLPPQCSPLLQHSLVPQNSPPSQCSPPALPLSVPSPL 1055
Query: 711 QPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVP 770
P G + ++ + + ++ P AL P TS + + P G+ A P
Sbjct: 1056 SPIGKVVGVSDEAELHEMETEKVSEPECPAL--EPSATSPLPS--PMGD-LSCPAPSPAP 1110
Query: 771 DGDG------RTSPLGGARSSSQRSPVG--PAGVRSPRPGSPQM----QASPSPGIAPKP 818
D T+PL G + + G P + S GSP + + +P + P
Sbjct: 1111 ALDDFSGLGEDTAPLDGIDAPGSQPEPGQTPGSLASELKGSPVLLDPEELAPVTPMEVYP 1170
Query: 819 KTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDR-SPQSPSQGARRQPGAA 877
+ TA + + + PR P+ AP P + + S S + PG+
Sbjct: 1171 ECKQTAGQGSPCEEQEEPRAPV------APTPPTLIKSDIVNEISNLSQGDASASFPGSE 1224
Query: 878 PLGKVLVDPESG 889
PL DPE G
Sbjct: 1225 PL-LGSPDPEGG 1235
Score = 45.4 bits (106), Expect = 3e-04
Identities = 65/232 (28%), Positives = 83/232 (35%), Gaps = 30/232 (12%)
Query: 779 LGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPRE 838
LG + +R G + P+PG PG+ PT + A +Q L +
Sbjct: 4153 LGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVG----IMPTVGQLRAQLQGVLAKN 4208
Query: 839 PLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPR 898
P +P Q + A R Q SQ R+ P G P G
Sbjct: 4209 PQLR--HLSPQQQQQLQALLMQRQLQQ-SQAVRQTPPYQEPG-TQTSPLQGLLGC----- 4259
Query: 899 QPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPI---PSLSLPPS 955
QP+L P++G E+ P GPP P AL G P GP+ P S P
Sbjct: 4260 QPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTG---PVLGPVHPTPPPSSPQE 4316
Query: 956 P-GPQALGSP--QLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGP 1004
P P L SP QLP ++ P GTP P P L PP P
Sbjct: 4317 PKRPSQLPSPSSQLPTEAQLPPTH-------PGTPKPQGPTLE-PPPGRVSP 4360
Score = 43.1 bits (100), Expect = 0.001
Identities = 179/823 (21%), Positives = 258/823 (31%), Gaps = 223/823 (27%)
Query: 378 RIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPS-PQNLSPWDRTTRRVSSPLFPEASSE 436
++P++VPS+ +P+ P + PR P+ P P+ T + P ASS
Sbjct: 2166 QVPAQVPSQDPFGLAPAYPLE--------PRFPTAPPTYPPYPSPTGAPAQPPMLGASSR 2217
Query: 437 WENQNPAVEETVS----RRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP 492
P T R PS P R PSL+ ++ E P A EP
Sbjct: 2218 PGAGQPGEFHTTPPGTPRHQPSTP------DPFLKPRCPSLDNLAVPESPGVGGGKASEP 2271
Query: 493 RSSPSP--PAFFPWEAPDRPIG----TWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEEL 546
SP P + E +G ++GP D G+ + + + + L
Sbjct: 2272 LLSPPPFGESRKALEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPL 2331
Query: 547 APPT----PSAPG------TPEPTEMQSPSTREISDLAFGGS-----QQSPEVAAPEPPG 591
P P +PG P P + +PS D+ GS Q P P+PP
Sbjct: 2332 TPRASQVEPQSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPP 2391
Query: 592 SH-----PVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAP--------- 637
P +L +D V ++ S PRP + P
Sbjct: 2392 PESCCALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYS 2451
Query: 638 --------------------------GFPAGA------QGSGLPAP-PADPCGEEGGESK 664
F AG+ G PA PA P GE +
Sbjct: 2452 RPPSRPQSRDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVP 2511
Query: 665 TQEPP----------ALGPPAPAHYT---SVFIKDFLPVVPHPYEPPEPSFD-------- 703
+ +PP +G P+P +T +V P VP P PP +
Sbjct: 2512 SGQPPNFVRSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPT 2571
Query: 704 ---------TVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGAL--------------A 740
TVA P+G + ST + + + +R P L
Sbjct: 2572 LGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHG 2631
Query: 741 LGRRPEVTSRVRAR-GPG-GENRDVEAQRLVPDGDGRTSPLGGARSSSQR---------- 788
+R +TS V R PG G + L D S L QR
Sbjct: 2632 ASQRSGITSPVEKREDPGTGMGSSLATAELPGTQDPGMSGLSQTELEKQRQRQRLRELLI 2691
Query: 789 --------------------SPVGPAGVRSPRPGSP---QMQASPSPGIAPKPKTPPTAP 825
VGP G P SP Q+ +P + K+
Sbjct: 2692 RQQIQRNTLRQEKETAAAAAGAVGPPGSWGAEPSSPAFEQLSRGQTPFAGTQDKS-SLVG 2750
Query: 826 EPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVD 885
P + + P+ L + P+ R S PP +P S +R+ G +
Sbjct: 2751 LPPSKLSGPI------LGPGSFPSDDR-LSRPPPPATPSSMDVNSRQLVGGSQAFYQRAP 2803
Query: 886 PESGRYYFVEAPRQPRLRVLFDPE------SGQYVEVLLPPSSPGPP---HRVYTPLALG 936
Y P Q + + L+ + S ++ PS+PGP + +PLA G
Sbjct: 2804 ------YPGSLPLQQQQQQLWQQQQATAATSMRFAMSARFPSTPGPELGRQALGSPLA-G 2856
Query: 937 LGLYPPAYG-PIPSLSLP-------------------PSPGPQALGSPQLPWVSE----A 972
+ P G P+P + P P PG P+ VSE
Sbjct: 2857 ISTRLPGPGEPVPGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRL 2916
Query: 973 GPLDGTYYLPVSGTP------NPAPPL--LLCAPPSSSGPTQP 1007
P +G L VSG P PAP L L P + GPT P
Sbjct: 2917 AP-EGLRGLAVSGLPPQKPSAPPAPELNNSLHPTPHTKGPTLP 2958
Score = 37.4 bits (85), Expect = 0.072
Identities = 102/467 (21%), Positives = 146/467 (31%), Gaps = 124/467 (26%)
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLG--P 609
S+PG PT + + + D A A E P +H G L PE + P
Sbjct: 4010 SSPGALGPTLLLTGKEQNTVDPAVSSE-------ATEGPSTHQGGPLAIGTTPESMATEP 4062
Query: 610 GE---AASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQG----SGLPAPPADPCGEEGGE 662
GE + SG ++ + +P+ + P Q S L G+ G
Sbjct: 4063 GEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQLGSG 4122
Query: 663 SKTQE---PPALGPPA------PAHYTSVFIKDFLPVVPHPYE------PPEPS------ 701
S ++ P L P+ P T + P++ P + PP+P
Sbjct: 4123 SSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSG 4182
Query: 702 --------FDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRA 753
TV + +Q GVL + + P ++ +++ AL + R+ + + VR
Sbjct: 4183 QGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQ---ALLMQRQLQQSQAVRQ 4239
Query: 754 RGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSP- 812
P E +TSPL G G + G P Q P
Sbjct: 4240 TPPYQEPGT------------QTSPLQGL-----------LGCQPQLGGFPGPQTGPLQE 4276
Query: 813 -GIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGAR 871
G P+P+ PP P P A+ T P PP SPQ P
Sbjct: 4277 LGAGPRPQGPPRLPAPPGALS-------------TGPVLGPVHPTPPPS-SPQEP----- 4317
Query: 872 RQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYT 931
++P P P S E LPP+ PG P
Sbjct: 4318 KRPSQLP----------------------------SPSSQLPTEAQLPPTHPGTPKPQGP 4349
Query: 932 PLALGLGLYPPAYGPIP----SLSLPPSPGPQALGSPQLPWVSEAGP 974
L G PA + S L P P L Q P S P
Sbjct: 4350 TLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAETQKPEQSSLVP 4396
Score = 32.3 bits (72), Expect = 2.3
Identities = 57/235 (24%), Positives = 82/235 (34%), Gaps = 45/235 (19%)
Query: 4 ALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSP----EPPDVGPDAKGPANWPWV 59
A+ PP G P++PA Q S G + T S P + GP ++P
Sbjct: 2713 AVGPPGSWGAE---PSSPAFEQLSRGQTPFAGTQDKSSLVGLPPSKLSGPILGPGSFP-- 2767
Query: 60 APGRGAGAQPRLSVSAQ--NSRQRHGPGSGF-PRGPGSGPRPPQPQLRTL-----PSGEM 111
+ R + P + S+ NSRQ G F R P G P Q Q + L +
Sbjct: 2768 SDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYPGSLPLQQQQQQLWQQQQATAAT 2827
Query: 112 EVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYL 171
+ F + F + + Q + A IS PGP P
Sbjct: 2828 SMRFAMSARFPSTPGPELGRQALGSPLAGISTRLPGPGEPV------------------- 2868
Query: 172 ELRPRGPSPAAPAQFECVEVALEEGAAPAR---PRTVPKRQIELRPRPQSPPRAA 223
P PA PAQF + +++G P P P ++ P + P R A
Sbjct: 2869 ------PGPAGPAQFIELRHNVQKGLGPGGTPFPGQGPPQRPRFYPVSEDPHRLA 2917
Score = 30.8 bits (68), Expect = 6.8
Identities = 31/107 (28%), Positives = 40/107 (37%), Gaps = 25/107 (23%)
Query: 1 MLTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVA 60
+LT L LPG Q P P G +G PG
Sbjct: 3627 LLTKLPGQLLPGHGLQPPQGPP-----GGQAGGLRLTPGG-----------------MAL 3664
Query: 61 PGRGAGAQPRLSVS-AQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTL 106
PG+ G P L+ + AQ +Q+H G+G GP G P LR+L
Sbjct: 3665 PGQPGG--PFLNTALAQQQQQQHSGGAGSLAGPSGGFFPGNLALRSL 3709
Score = 30.4 bits (67), Expect = 8.8
Identities = 20/57 (35%), Positives = 26/57 (45%), Gaps = 3/57 (5%)
Query: 175 PRGPSPAAPAQFECVEVALEEGAAPARPRTVP--KRQIELRPRPQS-PPRAAGAPRP 228
P PSPA+P VE+ E A P P +P RP+P++ PP RP
Sbjct: 4920 PLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRP 4976
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 94.7 bits (234), Expect = 4e-19
Identities = 182/709 (25%), Positives = 240/709 (33%), Gaps = 165/709 (23%)
Query: 20 APARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSR 79
AP + S G S A G+ P +G + VA G+ A R ++SA R
Sbjct: 94 APPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARR 153
Query: 80 QRHGPGSGFP----------RGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDR 129
GP G P G G P P R P E GP S A +
Sbjct: 154 DTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE-------GPRKSVSSASEH 206
Query: 130 EAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPR-GPS----PAAPA 184
TEP+ + P P + S AT L R GPS P APA
Sbjct: 207 ST----TEPSPAARRRPSAGGGLQRPASRSL----SSSATPLSSPARSGPSARGTPRAPA 258
Query: 185 QFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPR--PRLLLRTGSLDESLG 242
P++P+ PK LRP +PPR AP P + S
Sbjct: 259 H-------------PSQPK--PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAP 303
Query: 243 PLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRV 302
P +A +QT SP A PS AT T P T ++TH L PL
Sbjct: 304 PSPSAPPSLQTL----PSPPATPPSQAT---TSLGSP----TLQATHSFLPSPPLSPLA- 351
Query: 303 RDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREA 362
+ P +AP P+L ++ P + PL P+++ + F
Sbjct: 352 ---TPPPQAP---PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF-SPP 404
Query: 363 PDRTVQRARSPPFECRI-PSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRT 421
P VQ SPP + PS P P +PP Q P PSP
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP---------PSPP-------- 447
Query: 422 TRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEI 481
S P+ P A+ + P + P P + P+L P L
Sbjct: 448 ---ASPPMSPSATPPPQAPPPLAAPPLQLAKPPP------------QAPPALATPPL--- 489
Query: 482 PHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGL 541
++ PSPPA FP +AP P + SP T P P A
Sbjct: 490 -----------QALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA--------- 529
Query: 542 TQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVA--APEPPGSHPVGTL- 598
++ P P++P P +P D + G + + +A P PP P TL
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPG----PDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585
Query: 599 ---------DADKCPEVL-----GPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPA--- 641
A PE L GP A+ P P ++ ++ G PA
Sbjct: 586 GPDLAGHSSSATSTPEELRGYDSGPEGGAAASP----PPDAELAACHPAAWSRG-PAPPL 640
Query: 642 ---GAQGSGLPAPPADPCGE----------EGGESKTQEPPALGP-PAP 676
GA G+ LP PPA G EG ES T P AL P P+P
Sbjct: 641 AFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSP 689
Score = 94.0 bits (232), Expect = 6e-19
Identities = 198/773 (25%), Positives = 267/773 (34%), Gaps = 134/773 (17%)
Query: 142 SPLPPGPASPAAV----------PRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEV 191
SP PP P +PAA+ + GG AT E PR A P +
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR----AGPTRTSRPPA 87
Query: 192 ALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFV 251
+ AP T P SP RA+G RP L + G L+ +A
Sbjct: 88 SGRGERAPPAKNTSP-------GPVSSPGRASGTTRPGPLGQKG--------LRISA--- 129
Query: 252 QTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKA 311
+ +AR + EAP S+ + G+ R+T+ T A +R R R
Sbjct: 130 EETVARGKATEAPKRSALSAGA-------RRDTSGPTPGTPSPAMAR--RSRAAGTEVGL 180
Query: 312 PRPWPSLRERAIRRDKPAPGTE-PLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRA 370
PRP PS R P P TE P VSS+ + E AR+ R R+
Sbjct: 181 PRPAPSAR--------PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 232
Query: 371 RS---PPFECRIPSEVPSRAVRPRSPSPPRQ-TPNG--AVRGPRCPSPQN-----LSPWD 419
S P S PS PR+P+ P Q P G A+R P+ P+ L P
Sbjct: 233 LSSSATPLSSPARSG-PSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291
Query: 420 RTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLW 479
+ SP P + S P +T+ PSPP +Q SP+L+A +
Sbjct: 292 SSPLATPSPSAPPSPSA-----PPSLQTL----PSPPATPP-SQATTSLGSPTLQATHSF 341
Query: 480 EIPHSAVAD-AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQ 538
+P ++ A P +P A P +AP P + SP T P P
Sbjct: 342 -LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP----------- 389
Query: 539 NGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAA------PEPPGS 592
N L L P P P P++ +S A SQ P +AA P PP S
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS 449
Query: 593 HPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPP 652
P + P P A+ ++A P P+ AP A LP+PP
Sbjct: 450 PP---MSPSATPPPQAPPPLAAPPLQLAKPPPQ----------APPALATPPLQALPSPP 496
Query: 653 ADPCGE---EGGESKTQEPPALGPP-APAHYTSVFIK-----DFLPVVPHPYEPPEPSFD 703
A G+ S P A PP AP + ++ P + P PP P D
Sbjct: 497 ASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 556
Query: 704 TVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDV 763
T S P L A P + L G G TS ++
Sbjct: 557 T---SVSGPRLTL-ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS---------TPEEL 603
Query: 764 EAQRLVPDGDGRTSPLGGARSSS------QRSPVGPAGVRSPRPGSP-QMQASPSPGIAP 816
P+G SP A ++ R P P R PG+P + PG A
Sbjct: 604 RGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRG-APGAPLPWPPATGPGSAD 662
Query: 817 KPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQG 869
T P +A AP +P G + A A + RSP+ G
Sbjct: 663 GLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLG 715
Score = 91.7 bits (226), Expect = 3e-18
Identities = 163/674 (24%), Positives = 230/674 (34%), Gaps = 128/674 (18%)
Query: 379 IPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWE 438
IP P RA R+ PP + RG R P +N SP ++ +S +
Sbjct: 70 IPESAP-RAGPTRTSRPP-----ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK 123
Query: 439 NQNPAVEETVSR----RSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRS 494
+ EETV+R +P LS + +P +P++ +A + PR
Sbjct: 124 GLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRP 183
Query: 495 SPSPPAFFPWEAPDRPIG------TWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEE--L 546
+PS P E P + + T PSP P G + A L+ L
Sbjct: 184 APSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGG---LQRPASRSLSSSATPL 240
Query: 547 APPT---PSAPGTPE-PTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADK 602
+ P PSA GTP P P + + L + P+V P + +G L +
Sbjct: 241 SSPARSGPSARGTPRAPAHPSQPKPKGLQAL------RPPQVTPPRKDAAPALGPLSSSP 294
Query: 603 C--PEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEG 660
P P ++ +P P TT A S LP+PP P
Sbjct: 295 LATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT-- 352
Query: 661 GESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRA 720
PP PPA A LP + P PP AS P L
Sbjct: 353 -------PPPQAPPALA----------LPPLQAPPSPP----------ASPPLSPL---- 381
Query: 721 ENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLG 780
+T P + P ALA+ ++A P +P
Sbjct: 382 --ATPSP------QAPNALAVHL-------------------LQAPFSPPPSPPVQAPFS 414
Query: 781 GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL 840
S P P +P +Q PSP +P P +P P P A PL PL
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASP-PMSPSATPPPQAP--PPLAAPPL 471
Query: 841 ALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQP----GAAPLGKVLVDPESGRYYFVEA 896
LA + P P A + PP P P+ + P + P+ + P +A
Sbjct: 472 QLA-KPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP-------QA 523
Query: 897 P---RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTP---LALGLGLYPP-AYGPIPS 949
P P L+V P + ++ P +PGP V P LAL G PP + P +
Sbjct: 524 PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSST 583
Query: 950 LSLPPSPG--PQALGSPQLPWVSEAGPLDGTYYLP-----------VSGTPNPAPPLLLC 996
LS P G A +P+ ++GP G P + + PAPPL
Sbjct: 584 LSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFR 643
Query: 997 APPSSSGPTQPGKG 1010
P + P P G
Sbjct: 644 GAPGAPLPWPPATG 657
Score = 77.4 bits (189), Expect = 6e-14
Identities = 126/531 (23%), Positives = 183/531 (34%), Gaps = 80/531 (15%)
Query: 550 TPSAPGTPEPTEMQSPSTREISDLAFGG-----SQQSPEVAAPEPPGSHPVGTLDADKCP 604
TP PG+P P +P+ + A ++++ + P S P P
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRP 85
Query: 605 EVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGE------ 658
G GE A + P P T PG P G +G + A G+
Sbjct: 86 PASGRGERAPPAKNTS-PGPVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPK 143
Query: 659 ----EGGESKTQEPPALGPPAPAHY-------TSVFIKDFLPVVPH--PYEPPEPSFDTV 705
G + P G P+PA T V + P P E P S +
Sbjct: 144 RSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 203
Query: 706 ARDAS-QPNGVLRRRAE-------------NSTAKPFKRTEIRLPGALALGRRPEVTSRV 751
+ ++ +P+ RRR +S+A P P A R P S+
Sbjct: 204 SEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQP 263
Query: 752 RARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPS 811
+ +G + + ++ P LG SS +P P+ SP P +Q PS
Sbjct: 264 KPKGL----QALRPPQVTPPRKDAAPALGPLSSSPLATP-SPSAPPSPS-APPSLQTLPS 317
Query: 812 PGIAPKPKTPPTAPEPAA-AVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGA 870
P P + + P A + LP PL+ P P A + PP ++P SP
Sbjct: 318 PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASP 376
Query: 871 RRQPGAAPLGKVLVDPESGRYYFVEAP----RQPRLRVLFDPESGQYVEVLLPPSSPGPP 926
P A P + P + + ++AP P ++ F P + V P S PP
Sbjct: 377 PLSPLATPSPQA---PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 433
Query: 927 HRVYTPLA----------LGLGLYPPAYGPIP------SLSLPPSPGPQALGSPQL---- 966
PL + PP P P L+ PP P AL +P L
Sbjct: 434 SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493
Query: 967 -PWVSEAG--PLDGTYYLPVS--GTPNPAPPLLLCAPPSSSGPTQPGKGSL 1012
P S G P + LP+S TP P P +L AP P+ P +L
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTL 544
Score = 70.1 bits (170), Expect = 1e-11
Identities = 116/455 (25%), Positives = 151/455 (33%), Gaps = 58/455 (12%)
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEE 659
A + P +L P S RP + P +R L P + G+
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVT-PAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPR 76
Query: 660 GGESKTQEPPALGP---PAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVL 716
G ++T PPA G PA TS P P P + T G L
Sbjct: 77 AGPTRTSRPPASGRGERAPPAKNTS----------PGPVSSPGRASGTTRPGPLGQKG-L 125
Query: 717 RRRAENSTAKPFKRTEIRLPGALALGRR------------PEVTSRVRARGPG-GENRDV 763
R AE + A+ K TE AL+ G R P + R RA G G R
Sbjct: 126 RISAEETVARG-KATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184
Query: 764 EAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSP-------RPGSPQMQASPSPGIAP 816
+ R P +G + A S P PA R P RP S + +S +P +P
Sbjct: 185 PSARPRPPTEGPRKSVSSASEHSTTEP-SPAARRRPSAGGGLQRPASRSLSSSATPLSSP 243
Query: 817 KPKTPPTAPEPAAAVQAPLPREPLALAGRTAP--AQPRAASAP---PTDRSP-QSPSQGA 870
P P A P+ P L P PR +AP P SP +PS A
Sbjct: 244 ARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 302
Query: 871 RRQPGAAPLGKVLVDPESGR-YYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRV 929
P A P + L P + + P L+ + L P PP
Sbjct: 303 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 362
Query: 930 YTPLALGLGLYPPAYGPIPSLSLPPSPGPQALG----------SPQLPWVSEAGPLDGTY 979
PL PPA P+ L+ P P AL P P + P
Sbjct: 363 LPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 420
Query: 980 YLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFP 1014
P + P+ APP L APP P+ P + P
Sbjct: 421 VSPSATPPSQAPPSL-AAPPLQVPPSPPASPPMSP 454
Score = 51.6 bits (122), Expect = 4e-06
Identities = 80/317 (25%), Positives = 105/317 (33%), Gaps = 37/317 (11%)
Query: 6 APPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEP-PDVGPDAKGPANWPWVAPGRG 64
APP+ P P P A Q + + AP SP P P V PA+ P V+P
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSAT 426
Query: 65 AGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCS 124
+Q S++A + P + P P + P P P P ++
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL------------- 473
Query: 125 GADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRG-PSPAAP 183
+A P PL P+ PA+ P Q+ S L + P P P AP
Sbjct: 474 AKPPPQAPPALATP----PLQALPSPPASFPGQAPFSPSAS-----LPMSPLATPPPQAP 524
Query: 184 AQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTG-SLDESLG 242
+A P P P Q RP P + PR L L G S
Sbjct: 525 P-----VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 579
Query: 243 PLQAAAG---FVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRP 299
P +G ++ A E S G S P E A + + P
Sbjct: 580 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 639
Query: 300 LRVRDNSAPAKAPRPWP 316
L R AP AP PWP
Sbjct: 640 LAFR--GAPG-APLPWP 653
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 94.4 bits (233), Expect = 5e-19
Identities = 199/794 (25%), Positives = 275/794 (34%), Gaps = 137/794 (17%)
Query: 142 SPLPPGPASPAAVP----------RQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEV 191
SP PP P +PAA+ + GG AT E PR P A
Sbjct: 32 SPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRA-GPTRSAGTSSRNP 90
Query: 192 ALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFV 251
A A+ R P + P SP RA+G RP L + G L+ +A
Sbjct: 91 ASRPPASGRGERAPPAKNTSPGP-VSSPGRASGTTRPGPLGQKG--------LRISA--- 138
Query: 252 QTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKA 311
+ +AR + EAP S+ + G+ R+T+ T A +R R R
Sbjct: 139 EETVARGKATEAPKRSALSAGAR-------RDTSGPTPGTPSPAMAR--RSRAAGTEVGL 189
Query: 312 PRPWPSLRERAIRRDKPAPGTE-PLGPVSSSIFLQSEEKIQEARK--------------- 355
PRP PS R P P TE P VSS+ + E AR+
Sbjct: 190 PRPAPSAR--------PRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRS 241
Query: 356 ---TRFPREAPDRTVQRARSPPFECRIPSEVPSR---AVRPRSPSPPRQTPNGAVRGPRC 409
+ P +P R+ AR P PS+ + A+RP +PPR+ A+ GP
Sbjct: 242 LSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL-GPLS 300
Query: 410 PSP----------QNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRS-PSPPIL 458
SP Q+ +P SS L + ++ P+ S ++ PSPP
Sbjct: 301 SSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPAT 360
Query: 459 SQWNQCVAGERSPSLEAPSLWEIPHSAVAD-AVEPRSSPSPPAFFPWEAPDRPIGTWGPS 517
+Q SP+L+A + +P ++ A P +P A P +AP P + S
Sbjct: 361 PP-SQATTSLGSPTLQATHSF-LPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLS 418
Query: 518 PQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGG 577
P T P P N L L P P P P++ +S A
Sbjct: 419 PLATPSPQAP-----------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 467
Query: 578 SQQSPEVAAP------EPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLV 631
SQ P +AAP PP S P + P P A+ ++A P P+
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPP---MSPSATPPPQAPPPLAAPPLQLAKPPPQ------ 518
Query: 632 KTTYAPGFPAGAQGSGLPAPPADPCGE---EGGESKTQEPPALGPP-APAHYTSVFIK-- 685
AP A LP+PPA G+ S P A PP AP + ++
Sbjct: 519 ----APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVP 574
Query: 686 ---DFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALG 742
P + P PP P DT S P L A P + L G G
Sbjct: 575 PSPPASPTLQAPRRPPTPGPDT---SVSGPRLTLAL-APGPPPPPSRSPSSTLSGPDLAG 630
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS------QRSPVGPAGV 796
TS ++ P+G SP A ++ R P P
Sbjct: 631 HSSSATSTPE---------ELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAF 681
Query: 797 RSPRPGSP-QMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAAS 855
R PG+P + PG A T P +A AP +P G + A
Sbjct: 682 RGA-PGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAG 740
Query: 856 APPTDRSPQSPSQG 869
A + RSP+ G
Sbjct: 741 AGASSRSPKQARLG 754
Score = 90.1 bits (222), Expect = 9e-18
Identities = 185/741 (24%), Positives = 247/741 (33%), Gaps = 173/741 (23%)
Query: 7 PPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAG 66
P + P + AP + S G S A G+ P +G + VA G+
Sbjct: 90 PASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATE 149
Query: 67 AQPRLSVSAQNSRQRHGPGSGFP----------RGPGSGPRPPQPQLRTLPSGEMEVIFG 116
A R ++SA R GP G P G G P P R P E
Sbjct: 150 APKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTE------ 203
Query: 117 VGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPR 176
GP S A + TEP+ + P P + S AT L R
Sbjct: 204 -GPRKSVSSASEHST----TEPSPAARRRPSAGGGLQRPASRSL----SSSATPLSSPAR 254
Query: 177 -GPS----PAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLL 231
GPS P APA P++P+ PK LRP +PPR AP L
Sbjct: 255 SGPSARGTPRAPAH-------------PSQPK--PKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 232 ----LRTGSLDESLG-------PLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPE 280
L T S +L P + + LA L P+PS+ T S P
Sbjct: 300 SSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPA 359
Query: 281 T----------RETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAP 330
T T ++TH L PL + P +AP P+L ++ P
Sbjct: 360 TPPSQATTSLGSPTLQATHSFLPSPPLSPLA----TPPPQAP---PALALPPLQAPPSPP 412
Query: 331 GTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRI-PSEVPSRAVR 389
+ PL P+++ + F P VQ SPP + PS P
Sbjct: 413 ASPPLSPLATPSPQAPNALAVHLLQAPF-SPPPSPPVQAPFSPPASPPVSPSATPPSQAP 471
Query: 390 PRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVS 449
P +PP Q P PSP S P+ P A+ + P +
Sbjct: 472 PSLAAPPLQVP---------PSPP-----------ASPPMSPSATPPPQAPPPLAAPPLQ 511
Query: 450 RRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDR 509
P P + P+L P L ++ PSPPA FP +AP
Sbjct: 512 LAKPPP------------QAPPALATPPL--------------QALPSPPASFPGQAPFS 545
Query: 510 PIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTRE 569
P + SP T P P A ++ P P++P P +P
Sbjct: 546 PSASLPMSPLATPPPQAPPVLAA---------PLLQVPPSPPASPTLQAPRRPPTPG--- 593
Query: 570 ISDLAFGGSQQSPEVA--APEPPGSHPVGTL----------DADKCPEVL-----GPGEA 612
D + G + + +A P PP P TL A PE L GP
Sbjct: 594 -PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG 652
Query: 613 ASGRPRMAIPRPRDVRKLVKTTYAPGFPA------GAQGSGLPAPPADPCGE-------- 658
A+ P P ++ ++ G PA GA G+ LP PPA G
Sbjct: 653 AAASP----PPDAELAACHPAAWSRG-PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIY 707
Query: 659 --EGGESKTQEPPALGP-PAP 676
EG ES T P AL P P+P
Sbjct: 708 ETEGPESATPAPGALDPGPSP 728
Score = 89.4 bits (220), Expect = 2e-17
Identities = 161/673 (23%), Positives = 243/673 (36%), Gaps = 114/673 (16%)
Query: 380 PSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWEN 439
P P+R+ S +P + P RG R P +N SP ++ +S +
Sbjct: 75 PRAGPTRSAGTSSRNPASRPPASG-RGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 133
Query: 440 QNPAVEETVSR----RSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSS 495
+ EETV+R +P LS + +P +P++ +A + PR +
Sbjct: 134 LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 193
Query: 496 PSPPAFFPWEAPDRPIG------TWGPSPQETWDPMGPG------------SSIAFTQEA 537
PS P E P + + T PSP P G S+ + A
Sbjct: 194 PSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA 253
Query: 538 QNGLTQEELAPPTPSAPGTPEPTEMQS------PSTREISDLAFGGSQQSPEVAAPEPPG 591
++G + P P+ P P+P +Q+ R+ + A G SP +A P P
Sbjct: 254 RSGPSARG-TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP-LATPSPSA 311
Query: 592 SHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAP 651
+ L + P + ++S ++A P P +P P Q LP+P
Sbjct: 312 A-----LQSQAPPTLPATPHSSSLTCQLATPLPL-------APPSPSAPPSLQT--LPSP 357
Query: 652 PADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLP-------VVPHPYEPPEPSFDT 704
PA P +Q +LG P T FLP P P PP +
Sbjct: 358 PATP--------PSQATTSLGSP-----TLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 705 VARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVE 764
+ S P + P + P ALA+ ++A + V+
Sbjct: 405 LQAPPSPP--------ASPPLSPLATPSPQAPNALAV-------HLLQAPFSPPPSPPVQ 449
Query: 765 AQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA 824
A P + P+ + + ++P A P SP SP P P+ PP
Sbjct: 450 A----PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505
Query: 825 PEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTD---RSPQSPSQGARRQPGAAPLGK 881
P + P P+ P ALA T P Q A +PP ++P SPS P A P
Sbjct: 506 AAPPLQLAKPPPQAPPALA--TPPLQ--ALPSPPASFPGQAPFSPSASLPMSPLATP--- 558
Query: 882 VLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTP---LALGLG 938
P++ P L+V P + ++ P +PGP V P LAL G
Sbjct: 559 ---PPQA-----PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPG 610
Query: 939 -LYPPAYGPIPSLSLPPSPG--PQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLL 995
PP+ P +LS P G A +P+ ++GP G + +P P L
Sbjct: 611 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGG-----AAASPPPDAELAA 665
Query: 996 CAPPS-SSGPTQP 1007
C P + S GP P
Sbjct: 666 CHPAAWSRGPAPP 678
Score = 82.8 bits (203), Expect = 1e-15
Identities = 203/850 (23%), Positives = 280/850 (32%), Gaps = 188/850 (22%)
Query: 212 LRPRPQSPPRAAGAPRP---RLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSS 268
L PRP PR P R+L G++ PL AG + A + +P A S
Sbjct: 25 LTPRPPGSPRPPPPVTPAALRVLGAAGAVGRK--PLAERAGGIGGATIPESAPRAGPTRS 82
Query: 269 ATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKP 328
A T P +R A + + PAK P P +
Sbjct: 83 A---GTSSRNPASRPPASGRG--------------ERAPPAKNTSPGP------VSSPGR 119
Query: 329 APGTEPLGPVSSS-IFLQSEEKIQEARKTRFPREAP------------------DRTVQR 369
A GT GP+ + + +EE + + T P+ + +R
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR 179
Query: 370 ARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSP---QNLSPWDRTTRRVS 426
+R+ E +P PS RP + P + + + PSP + S R S
Sbjct: 180 SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 427 SPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEA--PSLWEIPHS 484
L +SS +PA +R +P P + + L+A P P
Sbjct: 240 RSL---SSSATPLSSPARSGPSARGTPRAPAHP------SQPKPKGLQALRPPQVTPPRK 290
Query: 485 AVADAVEPRSS-----PSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQN 539
A A+ P SS PSP A +AP P P SS Q A
Sbjct: 291 DAAPALGPLSSSPLATPSPSAALQSQAPPTL-------------PATPHSSSLTCQLA-- 335
Query: 540 GLTQEELAPPTPSAPGTPE--PTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGT 597
T LAPP+PSAP + + P+ +P ++ + L + Q+ P PP S P+ T
Sbjct: 336 --TPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLG-SPTLQATHSFLPSPPLS-PLAT 391
Query: 598 LDADKCPEV-LGPGEAASGRPR------MAIPRPRDVRKL-VKTTYAPGFPAGAQGSGLP 649
P + L P +A P +A P P+ L V AP P + P
Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
Query: 650 -APPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARD 708
+PPA P +Q PP+L P L V P P P S
Sbjct: 452 FSPPASPPVSPSATPPSQAPPSLAAPP------------LQVPPSPPASPPMS------- 492
Query: 709 ASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRL 768
P+ +A A P L L + P A P ++A
Sbjct: 493 ---PSATPPPQAPPPLAAP----------PLQLAKPPPQAPPALATPP------LQALPS 533
Query: 769 VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPA 828
P +P + S P P +P +Q PSP +P + P P P
Sbjct: 534 PPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPG 593
Query: 829 AAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQG---ARRQPGAAPLGKVLVD 885
PR LAL AP P PP RSP S G A A + L
Sbjct: 594 PDTSVSGPRLTLAL----APGPP-----PPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 644
Query: 886 PESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAY- 944
+SG PE G ++ PP P A +P A+
Sbjct: 645 YDSG------------------PEGG---------AAASPP-----PDAELAACHPAAWS 672
Query: 945 -GPIPSLSLPPSPGPQALGSPQLPWVSEAGP--LDGTYYLPVSGTPNPAPPLLLCAPPSS 1001
GP P L+ +PG LPW GP DG + + P A P P
Sbjct: 673 RGPAPPLAFRGAPG------APLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP 726
Query: 1002 SGPTQPGKGS 1011
S T GK +
Sbjct: 727 SPGTSGGKAA 736
Score = 75.1 bits (183), Expect = 3e-13
Identities = 136/569 (23%), Positives = 194/569 (34%), Gaps = 117/569 (20%)
Query: 550 TPSAPGTPEPTEMQSPST------------REISDLAFG-GSQQSPEVAAPEPPGSHPVG 596
TP PG+P P +P+ + +++ A G G PE +AP + G
Sbjct: 26 TPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE-SAPRAGPTRSAG 84
Query: 597 TLDADKC--PEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPAD 654
T + P G GE A + P P T PG P G +G + A
Sbjct: 85 TSSRNPASRPPASGRGERAPPAKNTS-PGPVSSPGRASGTTRPG-PLGQKGLRISAEETV 142
Query: 655 PCGE----------EGGESKTQEPPALGPPAPAHY-------TSVFIKDFLPVVPH--PY 695
G+ G + P G P+PA T V + P P
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202
Query: 696 EPPEPSFDTVARDAS-QPNGVLRRRAE-------------NSTAKPFKRTEIRLPGALAL 741
E P S + + ++ +P+ RRR +S+A P P A
Sbjct: 203 EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 262
Query: 742 GRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRP 801
R P S+ + +G + + ++ P LG SS +P A ++S P
Sbjct: 263 PRAPAHPSQPKPKGL----QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAP 318
Query: 802 ----GSPQMQ------ASPSPGIAPKPKTPP---TAPEPAA----------------AVQ 832
+P A+P P P P PP T P P A A
Sbjct: 319 PTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATH 378
Query: 833 APLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYY 892
+ LP PL+ P P A + PP ++P SP P A P + P + +
Sbjct: 379 SFLPSPPLSPLATPPPQAPPALALPPL-QAPPSPPASPPLSPLATPSPQA---PNALAVH 434
Query: 893 FVEAP----RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLA----------LGLG 938
++AP P ++ F P + V P S PP PL +
Sbjct: 435 LLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPS 494
Query: 939 LYPPAYGPIP------SLSLPPSPGPQALGSPQL-----PWVSEAG--PLDGTYYLPVS- 984
PP P P L+ PP P AL +P L P S G P + LP+S
Sbjct: 495 ATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 554
Query: 985 -GTPNPAPPLLLCAPPSSSGPTQPGKGSL 1012
TP P P +L AP P+ P +L
Sbjct: 555 LATPPPQAPPVLAAPLLQVPPSPPASPTL 583
Score = 72.0 bits (175), Expect = 3e-12
Identities = 112/436 (25%), Positives = 154/436 (35%), Gaps = 53/436 (12%)
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEE 659
A + P +L P S RP + P +R L GA G+ P A+ G
Sbjct: 18 AARAPGLLTPRPPGSPRPPPPVT-PAALRVL-----------GAAGAVGRKPLAERAGGI 65
Query: 660 GGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRR 719
GG + + P GP A +S P P P+ +T S P R
Sbjct: 66 GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPG-----R 119
Query: 720 AENSTAK-PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSP 778
A +T P + +R+ + R + R+ G RD G SP
Sbjct: 120 ASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPT-----PGTPSP 174
Query: 779 LGGARSSSQRSPVG-PAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAA-------- 829
RS + + VG P S RP P P ++ + T P PAA
Sbjct: 175 AMARRSRAAGTEVGLPRPAPSARPRPPT--EGPRKSVSSASEHSTTEPSPAARRRPSAGG 232
Query: 830 AVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQP-GAAPLGKVLVDPES 888
+Q P R +L+ P A S P +P++P+ ++ +P G L V P
Sbjct: 233 GLQRPASR---SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPP- 288
Query: 889 GRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHR--VYTPLALGLGLYPPAYGP 946
R A L P ++ PP+ P PH + LA L L PP+
Sbjct: 289 -RKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSA 347
Query: 947 IPSL-------SLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPP 999
PSL + PPS +LGSP L P L TP P P L PP
Sbjct: 348 PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPP---LSPLATPPPQAPPALALPP 404
Query: 1000 SSSGPTQPGKGSLFPL 1015
+ P+ P L PL
Sbjct: 405 LQAPPSPPASPPLSPL 420
Score = 52.8 bits (125), Expect = 2e-06
Identities = 105/488 (21%), Positives = 155/488 (31%), Gaps = 88/488 (18%)
Query: 3 TALAPPALPG-IPRQLPTAPARRQDSSGSS-----GSYYTAPGSPEPPDVGPDAKGPANW 56
T L+ PA G R P APA T P P +GP + P
Sbjct: 247 TPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLAT 306
Query: 57 PWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFG 116
P + + A P L + +S + P P S P P L+TLPS
Sbjct: 307 PSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP--PSLQTLPSPPAT---P 361
Query: 117 VGPLFGCSGADDREAQQQFTEPAFISPL-------------------PPGPASPAAVPRQ 157
G+ +A F +SPL P PASP P
Sbjct: 362 PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLA 421
Query: 158 SQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQ 217
+ P + A +L P P P+ P Q AP P P P Q
Sbjct: 422 TPSPQAPNALAVHLLQAPFSPPPSPPVQ------------APFSPPASPPVSPSATPPSQ 469
Query: 218 SPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRS 277
+PP A P L+ + P+ +A P+AP P +A +
Sbjct: 470 APPSLAAPP-----LQVPPSPPASPPMSPSA---------TPPPQAPPPLAAPPLQLAKP 515
Query: 278 EPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGP 337
P+ A + P S PA P P ++ A P
Sbjct: 516 PPQA-----------PPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPP 564
Query: 338 VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPR 397
V ++ LQ + + PR P +P + + + A+ P P PP
Sbjct: 565 VLAAPLLQVPPSPPASPTLQAPRRPP--------TPGPDTSVSGPRLTLALAPGPPPPPS 616
Query: 398 QTPNGAVRGP--------RCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVS 449
++P+ + GP +P+ L +D + + P +E +PA
Sbjct: 617 RSPSSTLSGPDLAGHSSSATSTPEELRGYD-SGPEGGAAASPPPDAELAACHPAAWS--- 672
Query: 450 RRSPSPPI 457
R P+PP+
Sbjct: 673 -RGPAPPL 679
Score = 51.6 bits (122), Expect = 4e-06
Identities = 80/317 (25%), Positives = 105/317 (33%), Gaps = 37/317 (11%)
Query: 6 APPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEP-PDVGPDAKGPANWPWVAPGRG 64
APP+ P P P A Q + + AP SP P P V PA+ P V+P
Sbjct: 407 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS-PPVSPSAT 465
Query: 65 AGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCS 124
+Q S++A + P + P P + P P P P ++
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQL------------- 512
Query: 125 GADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRG-PSPAAP 183
+A P PL P+ PA+ P Q+ S L + P P P AP
Sbjct: 513 AKPPPQAPPALATP----PLQALPSPPASFPGQAPFSPSAS-----LPMSPLATPPPQAP 563
Query: 184 AQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTG-SLDESLG 242
+A P P P Q RP P + PR L L G S
Sbjct: 564 P-----VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRS 618
Query: 243 PLQAAAG---FVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRP 299
P +G ++ A E S G S P E A + + P
Sbjct: 619 PSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPP 678
Query: 300 LRVRDNSAPAKAPRPWP 316
L R AP AP PWP
Sbjct: 679 LAFR--GAPG-APLPWP 692
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 87.8 bits (216), Expect = 5e-17
Identities = 144/634 (22%), Positives = 211/634 (33%), Gaps = 121/634 (19%)
Query: 260 SPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLR 319
+P+ PAP++ T EP T E A + P AP P P+
Sbjct: 243 TPKEPAPTTTKSAPTTPKEPAPTTTK-------EPAPTTP----KEPAPTTTKEPAPTTT 291
Query: 320 ERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRI 379
+ A K T P P ++ + +E T P+E T + A + P E
Sbjct: 292 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAP 350
Query: 380 PSEVPSRAVRPRSPSP-------PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPE 432
+ P+ P+P P T + P+ P+P TT+ +
Sbjct: 351 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 410
Query: 433 ASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP 492
A + + +P + + +P P +P AP+ + P P
Sbjct: 411 APTTPKEPSPTTTKEPAPTTPKEP----------APTTPKKPAPTTPKEPAPTTPKEPAP 460
Query: 493 RSSPSPPAFFPWE-APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
++ P P E AP P T P+ + P P T E T EELAP TP
Sbjct: 461 TTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 519
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P TP E +P+T P+ AAP P K P P E
Sbjct: 520 EEP-TPTTPEEPAPTT--------------PKAAAPNTP-----------KEPAPTTPKE 553
Query: 612 AASGRPRMAIPR-PRDVRKLVKTTYAPGFPAGAQGSGL--PAP--PADPCGEEGGESKTQ 666
A P+ P P++ AP P G + L PAP P P +E + T+
Sbjct: 554 PAPTTPKEPAPTTPKET--------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605
Query: 667 EPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAK 726
EP + PA T P P P P EP+ T A L+ A + K
Sbjct: 606 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKK 662
Query: 727 PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS 786
P P+ + +GP D A T+P
Sbjct: 663 P----------------APKELAPTTTKGPTSTTSDKPAP---------TTP-------K 690
Query: 787 QRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAP-LPREPLALAGR 845
+ +P P + P P +P+ P P TP T P + V P +EP +
Sbjct: 691 ETAPTTP---KEPAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 738
Query: 846 TAPAQPRAASAP---PTDRSPQSPSQGARRQPGA 876
+ P ++ P + SP+ P + P A
Sbjct: 739 PDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 772
Score = 76.3 bits (186), Expect = 1e-13
Identities = 128/594 (21%), Positives = 198/594 (33%), Gaps = 63/594 (10%)
Query: 432 EASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVE 491
+ S++ + + + +ET S S L+ ++ +A P+ +A + + P
Sbjct: 161 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA---KPTPKAETTTKGPALTTPKEPT 217
Query: 492 PRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
P + P + P E I + +P+E A T T +E AP T
Sbjct: 218 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP----------APTTTKSAPTTPKEPAPTTT 267
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P P E +T+E + + +P+ AP P P T + P P E
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT--PKE 324
Query: 612 AASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPAL 671
P+ P ++ AP P + P PA +E + T+EP
Sbjct: 325 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEPSPT 383
Query: 672 GPPAPAHYTS----VFIKDFLPVVPH--PYEPPEPSFDTVARDA----SQPNGVLRRRAE 721
P PA T+ K+ P P P EPS T A +P ++
Sbjct: 384 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 443
Query: 722 NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781
+T K T + P + T + A E ++L P + +P
Sbjct: 444 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 503
Query: 782 ARSS-SQRSPVGPAGVRSPRPGSPQMQASPSPGIA----PKPKTPPTAPEPAAAVQAPLP 836
+ + + + P P P +P+ A +P A PK P T EPA P
Sbjct: 504 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT----P 559
Query: 837 REPLALAGR-TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVE 895
+EP + TAP P+ +AP T + P + ++P L +
Sbjct: 560 KEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKP 615
Query: 896 APRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPS 955
AP P+ P+ P P P TP P P+ + P
Sbjct: 616 APTTPKGTAPTTPKE----PAPTTPKEPAPT----TPKGTA-----PTTLKEPAPTTPKK 662
Query: 956 PGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGK 1009
P P+ L + GP T P TP P P PT P K
Sbjct: 663 PAPKELAP-----TTTKGPTSTTSDKPAPTTPKETAP----TTPKEPAPTTPKK 707
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/254 (20%), Positives = 78/254 (30%), Gaps = 40/254 (15%)
Query: 143 PLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEE------- 195
P P P PA + P A P +P PA E +E
Sbjct: 554 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 613
Query: 196 --------GAAPARPR----TVPKRQIELRPRPQSP-------PRAAGAPRPRLLLRTGS 236
G AP P+ T PK P+ +P P P P+ L T
Sbjct: 614 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-- 671
Query: 237 LDESLGPLQAAAGFVQTALARKLSPEAP-APSSATFGSTGRSEPETRETARSTHVVLEKA 295
+ GP + ++ +P P P+ T + PET S V
Sbjct: 672 --TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTT 728
Query: 296 KSRPLRVR---DNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQE 352
P + D S P + P P E + ++ P T+ + +++K E
Sbjct: 729 TKEPTTIHKSPDESTPELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTTTAKDKTTE 787
Query: 353 ARKTRFPREAPDRT 366
R R P+ T
Sbjct: 788 ----RDLRTTPETT 797
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 87.8 bits (216), Expect = 5e-17
Identities = 144/634 (22%), Positives = 211/634 (33%), Gaps = 121/634 (19%)
Query: 260 SPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLR 319
+P+ PAP++ T EP T E A + P AP P P+
Sbjct: 284 TPKEPAPTTTKSAPTTPKEPAPTTTK-------EPAPTTP----KEPAPTTTKEPAPTTT 332
Query: 320 ERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRI 379
+ A K T P P ++ + +E T P+E T + A + P E
Sbjct: 333 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAP 391
Query: 380 PSEVPSRAVRPRSPSP-------PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPE 432
+ P+ P+P P T + P+ P+P TT+ +
Sbjct: 392 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 451
Query: 433 ASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP 492
A + + +P + + +P P +P AP+ + P P
Sbjct: 452 APTTPKEPSPTTTKEPAPTTPKEP----------APTTPKKPAPTTPKEPAPTTPKEPAP 501
Query: 493 RSSPSPPAFFPWE-APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
++ P P E AP P T P+ + P P T E T EELAP TP
Sbjct: 502 TTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 560
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P TP E +P+T P+ AAP P K P P E
Sbjct: 561 EEP-TPTTPEEPAPTT--------------PKAAAPNTP-----------KEPAPTTPKE 594
Query: 612 AASGRPRMAIPR-PRDVRKLVKTTYAPGFPAGAQGSGL--PAP--PADPCGEEGGESKTQ 666
A P+ P P++ AP P G + L PAP P P +E + T+
Sbjct: 595 PAPTTPKEPAPTTPKET--------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646
Query: 667 EPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAK 726
EP + PA T P P P P EP+ T A L+ A + K
Sbjct: 647 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKK 703
Query: 727 PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS 786
P P+ + +GP D A T+P
Sbjct: 704 P----------------APKELAPTTTKGPTSTTSDKPAP---------TTP-------K 731
Query: 787 QRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAP-LPREPLALAGR 845
+ +P P + P P +P+ P P TP T P + V P +EP +
Sbjct: 732 ETAPTTP---KEPAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 779
Query: 846 TAPAQPRAASAP---PTDRSPQSPSQGARRQPGA 876
+ P ++ P + SP+ P + P A
Sbjct: 780 PDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 813
Score = 76.3 bits (186), Expect = 1e-13
Identities = 128/594 (21%), Positives = 198/594 (33%), Gaps = 63/594 (10%)
Query: 432 EASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVE 491
+ S++ + + + +ET S S L+ ++ +A P+ +A + + P
Sbjct: 202 QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLA---KPTPKAETTTKGPALTTPKEPT 258
Query: 492 PRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
P + P + P E I + +P+E A T T +E AP T
Sbjct: 259 PTTPKEPASTTPKEPTPTTIKSAPTTPKEP----------APTTTKSAPTTPKEPAPTTT 308
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P P E +T+E + + +P+ AP P P T + P P E
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAPTT--PKE 365
Query: 612 AASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPAL 671
P+ P ++ AP P + P PA +E + T+EP
Sbjct: 366 PTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTTTKEPSPT 424
Query: 672 GPPAPAHYTS----VFIKDFLPVVPH--PYEPPEPSFDTVARDA----SQPNGVLRRRAE 721
P PA T+ K+ P P P EPS T A +P ++
Sbjct: 425 TPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA 484
Query: 722 NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781
+T K T + P + T + A E ++L P + +P
Sbjct: 485 PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTP 544
Query: 782 ARSS-SQRSPVGPAGVRSPRPGSPQMQASPSPGIA----PKPKTPPTAPEPAAAVQAPLP 836
+ + + + P P P +P+ A +P A PK P T EPA P
Sbjct: 545 EKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTT----P 600
Query: 837 REPLALAGR-TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVE 895
+EP + TAP P+ +AP T + P + ++P L +
Sbjct: 601 KEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTP---KKPAPKELAPTTTKEPTSTTCDKP 656
Query: 896 APRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPS 955
AP P+ P+ P P P TP P P+ + P
Sbjct: 657 APTTPKGTAPTTPKE----PAPTTPKEPAPT----TPKGTA-----PTTLKEPAPTTPKK 703
Query: 956 PGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGK 1009
P P+ L + GP T P TP P P PT P K
Sbjct: 704 PAPKELAP-----TTTKGPTSTTSDKPAPTTPKETAP----TTPKEPAPTTPKK 748
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/254 (20%), Positives = 78/254 (30%), Gaps = 40/254 (15%)
Query: 143 PLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEE------- 195
P P P PA + P A P +P PA E +E
Sbjct: 595 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 654
Query: 196 --------GAAPARPR----TVPKRQIELRPRPQSP-------PRAAGAPRPRLLLRTGS 236
G AP P+ T PK P+ +P P P P+ L T
Sbjct: 655 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-- 712
Query: 237 LDESLGPLQAAAGFVQTALARKLSPEAP-APSSATFGSTGRSEPETRETARSTHVVLEKA 295
+ GP + ++ +P P P+ T + PET S V
Sbjct: 713 --TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTT 769
Query: 296 KSRPLRVR---DNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQE 352
P + D S P + P P E + ++ P T+ + +++K E
Sbjct: 770 TKEPTTIHKSPDESTPELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTTTAKDKTTE 828
Query: 353 ARKTRFPREAPDRT 366
R R P+ T
Sbjct: 829 ----RDLRTTPETT 838
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 87.8 bits (216), Expect = 5e-17
Identities = 144/634 (22%), Positives = 211/634 (33%), Gaps = 121/634 (19%)
Query: 260 SPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLR 319
+P+ PAP++ T EP T E A + P AP P P+
Sbjct: 336 TPKEPAPTTTKSAPTTPKEPAPTTTK-------EPAPTTP----KEPAPTTTKEPAPTTT 384
Query: 320 ERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRI 379
+ A K T P P ++ + +E T P+E T + A + P E
Sbjct: 385 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAP 443
Query: 380 PSEVPSRAVRPRSPSP-------PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPE 432
+ P+ P+P P T + P+ P+P TT+ +
Sbjct: 444 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 503
Query: 433 ASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP 492
A + + +P + + +P P +P AP+ + P P
Sbjct: 504 APTTPKEPSPTTTKEPAPTTPKEP----------APTTPKKPAPTTPKEPAPTTPKEPAP 553
Query: 493 RSSPSPPAFFPWE-APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
++ P P E AP P T P+ + P P T E T EELAP TP
Sbjct: 554 TTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 612
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P TP E +P+T P+ AAP P K P P E
Sbjct: 613 EEP-TPTTPEEPAPTT--------------PKAAAPNTP-----------KEPAPTTPKE 646
Query: 612 AASGRPRMAIPR-PRDVRKLVKTTYAPGFPAGAQGSGL--PAP--PADPCGEEGGESKTQ 666
A P+ P P++ AP P G + L PAP P P +E + T+
Sbjct: 647 PAPTTPKEPAPTTPKET--------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698
Query: 667 EPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAK 726
EP + PA T P P P P EP+ T A L+ A + K
Sbjct: 699 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKK 755
Query: 727 PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS 786
P P+ + +GP D A T+P
Sbjct: 756 P----------------APKELAPTTTKGPTSTTSDKPAP---------TTP-------K 783
Query: 787 QRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAP-LPREPLALAGR 845
+ +P P + P P +P+ P P TP T P + V P +EP +
Sbjct: 784 ETAPTTP---KEPAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 831
Query: 846 TAPAQPRAASAP---PTDRSPQSPSQGARRQPGA 876
+ P ++ P + SP+ P + P A
Sbjct: 832 PDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 865
Score = 83.2 bits (204), Expect = 1e-15
Identities = 164/781 (20%), Positives = 263/781 (33%), Gaps = 86/781 (11%)
Query: 260 SPEAPAPSSA--TFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPS 317
S +AP PS A T ST + P+ ++ V+ + + V +N + + S
Sbjct: 75 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--S 132
Query: 318 LRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFEC 377
IR+ K + + +++ LQ + K+++ +K R ++ + PP
Sbjct: 133 SSSSTIRKIKSSKNS------AANRELQKKLKVKDNKKNRTKKKPTPK-------PPVVD 179
Query: 378 RIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEW 437
S + + + +P N P+ + + ++P R S P + S E
Sbjct: 180 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINP------RPSLPPNSDTSKET 233
Query: 438 E---NQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEI-PHSAVADAVEPR 493
N+ VE + + + + + + S+E S ++ P S V P+
Sbjct: 234 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 293
Query: 494 SSPS---PPAFFPWE----APDRPIGTWGPSPQETWDPMGPGS--SIAFTQEAQNGLTQE 544
+ + P P E P P T P T P + A T T +
Sbjct: 294 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 353
Query: 545 ELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCP 604
E AP T P P E +T+E + + +P+ AP P P T + P
Sbjct: 354 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAP 412
Query: 605 EVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESK 664
P E P+ P ++ AP P + P PA +E +
Sbjct: 413 TT--PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTT 469
Query: 665 TQEPPALGPPAPAHYTS----VFIKDFLPVVPH--PYEPPEPSFDTVARDA----SQPNG 714
T+EP P PA T+ K+ P P P EPS T A +P
Sbjct: 470 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 529
Query: 715 VLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDG 774
++ +T K T + P + T + A E ++L P
Sbjct: 530 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 589
Query: 775 RTSPLGGARSS-SQRSPVGPAGVRSPRPGSPQMQASPSPGIA----PKPKTPPTAPEPAA 829
+ +P + + + + P P P +P+ A +P A PK P T EPA
Sbjct: 590 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 649
Query: 830 AVQAPLPREPLALAGR-TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPES 888
P+EP + TAP P+ +AP T + P + ++P L +
Sbjct: 650 TT----PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTP---KKPAPKELAPTTTKEPT 701
Query: 889 GRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIP 948
AP P+ P+ P P P TP P P
Sbjct: 702 STTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPT----TPKGTA-----PTTLKEP 748
Query: 949 SLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPG 1008
+ + P P P+ L + GP T P TP P P PT P
Sbjct: 749 APTTPKKPAPKELAP-----TTTKGPTSTTSDKPAPTTPKETAP----TTPKEPAPTTPK 799
Query: 1009 K 1009
K
Sbjct: 800 K 800
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/254 (20%), Positives = 78/254 (30%), Gaps = 40/254 (15%)
Query: 143 PLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEE------- 195
P P P PA + P A P +P PA E +E
Sbjct: 647 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 706
Query: 196 --------GAAPARPR----TVPKRQIELRPRPQSP-------PRAAGAPRPRLLLRTGS 236
G AP P+ T PK P+ +P P P P+ L T
Sbjct: 707 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-- 764
Query: 237 LDESLGPLQAAAGFVQTALARKLSPEAP-APSSATFGSTGRSEPETRETARSTHVVLEKA 295
+ GP + ++ +P P P+ T + PET S V
Sbjct: 765 --TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTT 821
Query: 296 KSRPLRVR---DNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQE 352
P + D S P + P P E + ++ P T+ + +++K E
Sbjct: 822 TKEPTTIHKSPDESTPELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTTTAKDKTTE 880
Query: 353 ARKTRFPREAPDRT 366
R R P+ T
Sbjct: 881 ----RDLRTTPETT 890
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 87.8 bits (216), Expect = 5e-17
Identities = 144/634 (22%), Positives = 211/634 (33%), Gaps = 121/634 (19%)
Query: 260 SPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLR 319
+P+ PAP++ T EP T E A + P AP P P+
Sbjct: 377 TPKEPAPTTTKSAPTTPKEPAPTTTK-------EPAPTTP----KEPAPTTTKEPAPTTT 425
Query: 320 ERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRI 379
+ A K T P P ++ + +E T P+E T + A + P E
Sbjct: 426 KSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEPAP 484
Query: 380 PSEVPSRAVRPRSPSP-------PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPE 432
+ P+ P+P P T + P+ P+P TT+ +
Sbjct: 485 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 544
Query: 433 ASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP 492
A + + +P + + +P P +P AP+ + P P
Sbjct: 545 APTTPKEPSPTTTKEPAPTTPKEP----------APTTPKKPAPTTPKEPAPTTPKEPAP 594
Query: 493 RSSPSPPAFFPWE-APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTP 551
++ P P E AP P T P+ + P P T E T EELAP TP
Sbjct: 595 TTTKKPAPTTPKEPAPTTPKET-APTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTP 653
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGE 611
P TP E +P+T P+ AAP P K P P E
Sbjct: 654 EEP-TPTTPEEPAPTT--------------PKAAAPNTP-----------KEPAPTTPKE 687
Query: 612 AASGRPRMAIPR-PRDVRKLVKTTYAPGFPAGAQGSGL--PAP--PADPCGEEGGESKTQ 666
A P+ P P++ AP P G + L PAP P P +E + T+
Sbjct: 688 PAPTTPKEPAPTTPKET--------APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739
Query: 667 EPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAK 726
EP + PA T P P P P EP+ T A L+ A + K
Sbjct: 740 EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPT---TLKEPAPTTPKK 796
Query: 727 PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSS 786
P P+ + +GP D A T+P
Sbjct: 797 P----------------APKELAPTTTKGPTSTTSDKPAP---------TTP-------K 824
Query: 787 QRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAP-LPREPLALAGR 845
+ +P P + P P +P+ P P TP T P + V P +EP +
Sbjct: 825 ETAPTTP---KEPAPTTPKK---------PAPTTPETPPPTTSEVSTPTTTKEPTTIHKS 872
Query: 846 TAPAQPRAASAP---PTDRSPQSPSQGARRQPGA 876
+ P ++ P + SP+ P + P A
Sbjct: 873 PDESTPELSAEPTPKALENSPKEPGVPTTKTPAA 906
Score = 83.2 bits (204), Expect = 1e-15
Identities = 164/781 (20%), Positives = 263/781 (33%), Gaps = 86/781 (11%)
Query: 260 SPEAPAPSSA--TFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPS 317
S +AP PS A T ST + P+ ++ V+ + + V +N + + S
Sbjct: 116 SKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSENQESSSSSSS--S 173
Query: 318 LRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFEC 377
IR+ K + + +++ LQ + K+++ +K R ++ + PP
Sbjct: 174 SSSSTIRKIKSSKNS------AANRELQKKLKVKDNKKNRTKKKPTPK-------PPVVD 220
Query: 378 RIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEW 437
S + + + +P N P+ + + ++P R S P + S E
Sbjct: 221 EAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINP------RPSLPPNSDTSKET 274
Query: 438 E---NQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEI-PHSAVADAVEPR 493
N+ VE + + + + + + S+E S ++ P S V P+
Sbjct: 275 SLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPK 334
Query: 494 SSPS---PPAFFPWE----APDRPIGTWGPSPQETWDPMGPGS--SIAFTQEAQNGLTQE 544
+ + P P E P P T P T P + A T T +
Sbjct: 335 AETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPK 394
Query: 545 ELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCP 604
E AP T P P E +T+E + + +P+ AP P P T + P
Sbjct: 395 EPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTP-KKPAPTTPKEPAP 453
Query: 605 EVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESK 664
P E P+ P ++ AP P + P PA +E +
Sbjct: 454 TT--PKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPT-TPKEPAPTTPKEPAPTT 510
Query: 665 TQEPPALGPPAPAHYTS----VFIKDFLPVVPH--PYEPPEPSFDTVARDA----SQPNG 714
T+EP P PA T+ K+ P P P EPS T A +P
Sbjct: 511 TKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAP 570
Query: 715 VLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDG 774
++ +T K T + P + T + A E ++L P
Sbjct: 571 TTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPE 630
Query: 775 RTSPLGGARSS-SQRSPVGPAGVRSPRPGSPQMQASPSPGIA----PKPKTPPTAPEPAA 829
+ +P + + + + P P P +P+ A +P A PK P T EPA
Sbjct: 631 KLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAP 690
Query: 830 AVQAPLPREPLALAGR-TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPES 888
P+EP + TAP P+ +AP T + P + ++P L +
Sbjct: 691 TT----PKEPAPTTPKETAPTTPK-GTAPTTLKEPAPTTP---KKPAPKELAPTTTKEPT 742
Query: 889 GRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIP 948
AP P+ P+ P P P TP P P
Sbjct: 743 STTCDKPAPTTPKGTAPTTPKE----PAPTTPKEPAPT----TPKGTA-----PTTLKEP 789
Query: 949 SLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPG 1008
+ + P P P+ L + GP T P TP P P PT P
Sbjct: 790 APTTPKKPAPKELAP-----TTTKGPTSTTSDKPAPTTPKETAP----TTPKEPAPTTPK 840
Query: 1009 K 1009
K
Sbjct: 841 K 841
Score = 32.0 bits (71), Expect = 3.0
Identities = 53/254 (20%), Positives = 78/254 (30%), Gaps = 40/254 (15%)
Query: 143 PLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEE------- 195
P P P PA + P A P +P PA E +E
Sbjct: 688 PAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCD 747
Query: 196 --------GAAPARPR----TVPKRQIELRPRPQSP-------PRAAGAPRPRLLLRTGS 236
G AP P+ T PK P+ +P P P P+ L T
Sbjct: 748 KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT-- 805
Query: 237 LDESLGPLQAAAGFVQTALARKLSPEAP-APSSATFGSTGRSEPETRETARSTHVVLEKA 295
+ GP + ++ +P P P+ T + PET S V
Sbjct: 806 --TTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTS-EVSTPTT 862
Query: 296 KSRPLRVR---DNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQE 352
P + D S P + P P E + ++ P T+ + +++K E
Sbjct: 863 TKEPTTIHKSPDESTPELSAEPTPKALENS-PKEPGVPTTKTPAATKPEMTTTAKDKTTE 921
Query: 353 ARKTRFPREAPDRT 366
R R P+ T
Sbjct: 922 ----RDLRTTPETT 931
>gi|169167062 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 84.3 bits (207), Expect = 5e-16
Identities = 108/377 (28%), Positives = 149/377 (39%), Gaps = 45/377 (11%)
Query: 613 ASGRPRMAIPRP--RDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPA 670
A RPR P +DV + P P+ + A G G+ Q P
Sbjct: 1396 ARERPRSLYIPPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFP-QGPSP 1454
Query: 671 LGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKR 730
P A S ++ L + P PP D V S N E S +
Sbjct: 1455 ESPSAAKGIKSQGLRS-LKISPATRAPP----DEVTNRKSGSN------LEKSNSDCENY 1503
Query: 731 TEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSP 790
I L G+ A G E+ SR A G N +P R+ ++ S
Sbjct: 1504 LTIPLKGSSAAG---ELLSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGT 1560
Query: 791 VGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA----PEPAAAVQAPLPREPLALAGRT 846
PA +P +P+ + PG P+ PPT P +Q P + L + +
Sbjct: 1561 SRPAW--RTKPDNPRETVAAPPG-PQSPEHPPTTIYHQPPLPFTLQGAQP-QVLCFSPPS 1616
Query: 847 APAQPRAASAP-PTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVL 905
PA AASAP PTD Q+ Q +R K+L+D +G+YY V+ P QP R L
Sbjct: 1617 MPAPAPAASAPVPTDPFQQAQPQQTQR--------KMLLDVTTGQYYLVDTPVQPMTRRL 1668
Query: 906 FDPESGQYVEVLL--PPSSPGPPHRVYTPLALGLGLYPPAY--------GPIPSLSLPPS 955
FDPE+GQYV+V + + P PLAL G Y P Y +P+ +L P+
Sbjct: 1669 FDPETGQYVDVPMTSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQPT 1728
Query: 956 PGPQA-LGSPQLPWVSE 971
P +A GS P V+E
Sbjct: 1729 PIARAPRGSELSPMVAE 1745
Score = 31.2 bits (69), Expect = 5.2
Identities = 33/131 (25%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 757 GGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG---SPQMQASPSPG 813
G + + L + D + L S++ P RP S + +S G
Sbjct: 444 GSDETPGDITSLTEEDDDNSCYLSTTPSTNTTRTPSPTSSDLARPNAGRSGRDTSSTEVG 503
Query: 814 IAPK---PKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASA--------PPTDRS 862
P P PPT P A + PLP P A +G A A SA P R+
Sbjct: 504 SGPSDSGPTPPPTGPGTAPLTE-PLPETPEAASGAAAAAASSCGSAASQILLSIKPASRA 562
Query: 863 PQSPSQGARRQ 873
PS +Q
Sbjct: 563 INEPSNVRAKQ 573
>gi|113416182 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 84.3 bits (207), Expect = 5e-16
Identities = 108/377 (28%), Positives = 149/377 (39%), Gaps = 45/377 (11%)
Query: 613 ASGRPRMAIPRP--RDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPA 670
A RPR P +DV + P P+ + A G G+ Q P
Sbjct: 1396 ARERPRSLYIPPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFP-QGPSP 1454
Query: 671 LGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKR 730
P A S ++ L + P PP D V S N E S +
Sbjct: 1455 ESPSAAKGIKSQGLRS-LKISPATRAPP----DEVTNRKSGSN------LEKSNSDCENY 1503
Query: 731 TEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSP 790
I L G+ A G E+ SR A G N +P R+ ++ S
Sbjct: 1504 LTIPLKGSSAAG---ELLSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGT 1560
Query: 791 VGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA----PEPAAAVQAPLPREPLALAGRT 846
PA +P +P+ + PG P+ PPT P +Q P + L + +
Sbjct: 1561 SRPAW--RTKPDNPRETVAAPPG-PQSPEHPPTTIYHQPPLPFTLQGAQP-QVLCFSPPS 1616
Query: 847 APAQPRAASAP-PTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVL 905
PA AASAP PTD Q+ Q +R K+L+D +G+YY V+ P QP R L
Sbjct: 1617 MPAPAPAASAPVPTDPFQQAQPQQTQR--------KMLLDVTTGQYYLVDTPVQPMTRRL 1668
Query: 906 FDPESGQYVEVLL--PPSSPGPPHRVYTPLALGLGLYPPAY--------GPIPSLSLPPS 955
FDPE+GQYV+V + + P PLAL G Y P Y +P+ +L P+
Sbjct: 1669 FDPETGQYVDVPMTSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQPT 1728
Query: 956 PGPQA-LGSPQLPWVSE 971
P +A GS P V+E
Sbjct: 1729 PIARAPRGSELSPMVAE 1745
Score = 31.2 bits (69), Expect = 5.2
Identities = 33/131 (25%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 757 GGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG---SPQMQASPSPG 813
G + + L + D + L S++ P RP S + +S G
Sbjct: 444 GSDETPGDITSLTEEDDDNSCYLSTTPSTNTTRTPSPTSSDLARPNAGRSGRDTSSTEVG 503
Query: 814 IAPK---PKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASA--------PPTDRS 862
P P PPT P A + PLP P A +G A A SA P R+
Sbjct: 504 SGPSDSGPTPPPTGPGTAPLTE-PLPETPEAASGAAAAAASSCGSAASQILLSIKPASRA 562
Query: 863 PQSPSQGARRQ 873
PS +Q
Sbjct: 563 INEPSNVRAKQ 573
>gi|113415686 PREDICTED: hypothetical protein LOC285556 [Homo sapiens]
Length = 1826
Score = 84.3 bits (207), Expect = 5e-16
Identities = 108/377 (28%), Positives = 149/377 (39%), Gaps = 45/377 (11%)
Query: 613 ASGRPRMAIPRP--RDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPA 670
A RPR P +DV + P P+ + A G G+ Q P
Sbjct: 1396 ARERPRSLYIPPVHKDVERTQPLQPLPPLPSNRNVFTVSASSIQKTGGVAGKFP-QGPSP 1454
Query: 671 LGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKR 730
P A S ++ L + P PP D V S N E S +
Sbjct: 1455 ESPSAAKGIKSQGLRS-LKISPATRAPP----DEVTNRKSGSN------LEKSNSDCENY 1503
Query: 731 TEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSP 790
I L G+ A G E+ SR A G N +P R+ ++ S
Sbjct: 1504 LTIPLKGSSAAG---ELLSRPGASREGPPNSSAATLCSLPPLSARSQVPSSSKGSQVSGT 1560
Query: 791 VGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA----PEPAAAVQAPLPREPLALAGRT 846
PA +P +P+ + PG P+ PPT P +Q P + L + +
Sbjct: 1561 SRPAW--RTKPDNPRETVAAPPG-PQSPEHPPTTIYHQPPLPFTLQGAQP-QVLCFSPPS 1616
Query: 847 APAQPRAASAP-PTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVL 905
PA AASAP PTD Q+ Q +R K+L+D +G+YY V+ P QP R L
Sbjct: 1617 MPAPAPAASAPVPTDPFQQAQPQQTQR--------KMLLDVTTGQYYLVDTPVQPMTRRL 1668
Query: 906 FDPESGQYVEVLL--PPSSPGPPHRVYTPLALGLGLYPPAY--------GPIPSLSLPPS 955
FDPE+GQYV+V + + P PLAL G Y P Y +P+ +L P+
Sbjct: 1669 FDPETGQYVDVPMTSQQQAVAPMSISVPPLALSPGAYGPTYMIYPGFLPTVLPTNALQPT 1728
Query: 956 PGPQA-LGSPQLPWVSE 971
P +A GS P V+E
Sbjct: 1729 PIARAPRGSELSPMVAE 1745
Score = 31.2 bits (69), Expect = 5.2
Identities = 33/131 (25%), Positives = 45/131 (34%), Gaps = 15/131 (11%)
Query: 757 GGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG---SPQMQASPSPG 813
G + + L + D + L S++ P RP S + +S G
Sbjct: 444 GSDETPGDITSLTEEDDDNSCYLSTTPSTNTTRTPSPTSSDLARPNAGRSGRDTSSTEVG 503
Query: 814 IAPK---PKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASA--------PPTDRS 862
P P PPT P A + PLP P A +G A A SA P R+
Sbjct: 504 SGPSDSGPTPPPTGPGTAPLTE-PLPETPEAASGAAAAAASSCGSAASQILLSIKPASRA 562
Query: 863 PQSPSQGARRQ 873
PS +Q
Sbjct: 563 INEPSNVRAKQ 573
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 84.0 bits (206), Expect = 7e-16
Identities = 187/799 (23%), Positives = 283/799 (35%), Gaps = 141/799 (17%)
Query: 147 GPASPAAVPRQSQVPDGGSRWATYL-ELRPRG---PSPAAPAQFECVEVALEE----GAA 198
GPA P + P S P ATYL +L P P+ A C L A+
Sbjct: 333 GPAEPLS-PAMSISPQ-----ATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSAS 386
Query: 199 PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
PA R++ + P+P+S ++ + T S +S + + + + +
Sbjct: 387 PASVRSLGRFSSVSSPQPRSRHPSSSSD-------TWSHSQSSDTIVSDGSTLSSKGGSE 439
Query: 259 LSPEAPAPSSATF----GSTGRSEPETRETARSTHVVLEKAKS----RPLRVRDNSAPAK 310
PE+ S++ G +GR P TA ++ + ++ R + +R P
Sbjct: 440 GQPESSTASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPP 499
Query: 311 APRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRA 370
PR SL +R + P GP+ E+ Q+ + R P A
Sbjct: 500 PPRRTHSLHQRGL--------AVPDGPLGLP---PKPERKQQPQLPRPPTTGGSEGAGAA 548
Query: 371 RSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLF 430
PP P + P +P G+ R PR P + LSP + + +P
Sbjct: 549 PCPP--------------NPANSWVPGLSPGGSRRPPRSPE-RTLSPSSGYSSQSGTPTL 593
Query: 431 PEA------SSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEI--- 481
P +S + Q P E S RSP + S + P+ S +I
Sbjct: 594 PPKGLAGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTP 653
Query: 482 --------PHSAVADAVEPRSS------PSPPAFFPWEAPDRPIGTWGPSPQETWDPMGP 527
PH V P S P+ PA P+ T SPQ P P
Sbjct: 654 LGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQS---PPTP 710
Query: 528 GSSIAFTQEAQNGLTQEELAPPTP--SAPGTPEPTE-----MQSPSTREISDLAFGGSQQ 580
+++ QE+ +++++ PP+P S P PT+ +++PS E ++ Q
Sbjct: 711 QTTLTPLQESPV-ISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPL----Q 765
Query: 581 SPEVAAPEPPGSHPVGTLDADKCP------EVLGPGEAA-SGRPRM-AIPRPRDVRKLVK 632
P P PP AD P V P A SG P + + P
Sbjct: 766 DPNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATAL 825
Query: 633 TTYAPGFPAGAQGSGLPAPPADPCG--------EEGGESKTQEPPALGPPAPAHYTSVFI 684
PG P PAP + G E G SK PP AP S+
Sbjct: 826 QIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQ 885
Query: 685 KDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGR- 743
L V P P P A S P LRR A + A P L A+ L
Sbjct: 886 MVRLRSVGAPGGAPTP-----ALGPSAPQKPLRR-ALSGRASPVPAPSSGLHAAVRLKAC 939
Query: 744 ---RPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPR 800
E S + GP P+ + R P A ++S G ++ R
Sbjct: 940 SLAASEGLSSAQPNGP-------------PEAEPRP-PQSPASTASFIFSKGSRKLQLER 985
Query: 801 PGSPQMQASPSPGIAPKPKT-----PPTAPEPAAAVQAPLPREP-LALAGRTAPAQPRA- 853
P SP+ QA + + ++ PP AP+ + P+ R+P + + +P+ PRA
Sbjct: 986 PVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAE 1045
Query: 854 -ASAPPTDRSPQSPSQGAR 871
+APPT+ P + + R
Sbjct: 1046 PLTAPPTNGLPHTQDRTKR 1064
Score = 60.8 bits (146), Expect = 6e-09
Identities = 157/616 (25%), Positives = 213/616 (34%), Gaps = 124/616 (20%)
Query: 9 ALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVG--------PDAKGPAN-W-PW 58
A+P P LP P R+Q P P PP G P PAN W P
Sbjct: 513 AVPDGPLGLPPKPERKQQ-----------PQLPRPPTTGGSEGAGAAPCPPNPANSWVPG 561
Query: 59 VAPGRGAGAQPR-----LSVSAQNSRQRHGPG------SGFPRGPGSGPRPPQPQLRTLP 107
++PG G+ PR LS S+ S Q P +G P PG P ++ +L
Sbjct: 562 LSPG-GSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLR 620
Query: 108 SGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISPL------PPGPASPAAVPRQSQVP 161
S V + L CS + D A + P ++PL PP P PA S P
Sbjct: 621 SPGASVSSSLTSL--CSSSSD-PAPSDRSGPQILTPLGDRFVIPPHPKVPAPF---SPPP 674
Query: 162 DGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRP------- 214
+PR P+PAAPA V A P++ P Q L P
Sbjct: 675 S-----------KPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVI 723
Query: 215 -----RPQSPPRAAGAP-----RPRLLLRTGSLDESL-GPLQAAAGFVQTALA---RKLS 260
P SPP + P +P +++ S E+ PLQ A + LS
Sbjct: 724 SKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLS 783
Query: 261 -PEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLR 319
+ P P A F + PE + S +V A S P +P P P+
Sbjct: 784 MADFPPPEEAFFSV---ASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPA-- 838
Query: 320 ERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPRE---APDRT-----VQRAR 371
PAP + G V+ L +E + ++ PRE AP T + R R
Sbjct: 839 -----PPAPAPASSAPGHVAK---LPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLR 890
Query: 372 SPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFP 431
S P P+ A+ P +P P + A+ G P P S R + L
Sbjct: 891 S----VGAPGGAPTPALGPSAPQKPLRR---ALSGRASPVPAPSSGLHAAVRLKACSL-- 941
Query: 432 EASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAV- 490
AS + P R P P + G R LE P E + V
Sbjct: 942 AASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVA 1001
Query: 491 EPRS-SPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEE--LA 547
E RS S P P ++P P P+ S+ A + E A
Sbjct: 1002 ELRSISEQRPPQAPKKSPKAP------------PPVARKPSVGVPPPASPSYPRAEPLTA 1049
Query: 548 PPTPSAPGTPEPTEMQ 563
PPT P T + T+ +
Sbjct: 1050 PPTNGLPHTQDRTKRE 1065
Score = 59.7 bits (143), Expect = 1e-08
Identities = 125/542 (23%), Positives = 175/542 (32%), Gaps = 61/542 (11%)
Query: 513 TWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPS--APGTPEPTEMQSPSTREI 570
T G P E P+ P SI+ + L + PPT A G + S
Sbjct: 329 TGGAGPAE---PLSPAMSISPQATYLSKLIPHAVLPPTVDVVALGRCSLRTLSRCSLHSA 385
Query: 571 SDLAFGGSQQSPEVAAPEPPGSHPVGTLD----ADKCPEVLGPGEAASGRPRM-AIPRPR 625
S + + V++P+P HP + D + ++ G S + P
Sbjct: 386 SPASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESS 445
Query: 626 DVRKLVKTTYAPGFPAGAQGSGLPAPPADPC-----GEEGGESKTQEPPALGPPAPAHYT 680
V G G+ G A +D G+ G S + PP P
Sbjct: 446 TASNSVVPPPQGGSGRGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTH 505
Query: 681 SVFIKDFLPVVPHPYE-PPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIR--LPG 737
S+ + L V P PP+P + P +E + A P +PG
Sbjct: 506 SLHQRG-LAVPDGPLGLPPKPERK---QQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPG 561
Query: 738 ALALGRRPEVTSRVRARGPG-GENRDVEAQRLVPDG-------DGRTSPLGGARSSSQRS 789
G R S R P G + L P G G+ P R +S RS
Sbjct: 562 LSPGGSRRPPRSPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVTSLRS 621
Query: 790 PVGPAGVRSPRPGSPQMQASPSPG----------------IAPKPKTPPTAPEPAAAVQA 833
P A V S + P+P I P PK P P + ++
Sbjct: 622 P--GASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRS 679
Query: 834 PLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYF 893
P P P A P A P +SP +P + + K P S +
Sbjct: 680 PNPAAPALAAPAVVPGPVSTTDASP--QSPPTPQTTLTPLQESPVISKDQSPPPSPPPSY 737
Query: 894 VEAP---RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSL 950
P ++P + V S E L P+ P PP L + +PP S+
Sbjct: 738 HPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLSMADFPPPEEAFFSV 797
Query: 951 SLPPSPGPQALGSPQL---PWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQP 1007
+ P GP GSP+L P S + P S P PAPP P+SS P
Sbjct: 798 ASPEPAGPS--GSPELVSSPAASSSSATALQIQPPGSPDPPPAPP---APAPASSAPGHV 852
Query: 1008 GK 1009
K
Sbjct: 853 AK 854
Score = 55.1 bits (131), Expect = 3e-07
Identities = 72/304 (23%), Positives = 104/304 (34%), Gaps = 41/304 (13%)
Query: 137 EPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRG---PSPAAPAQFECVEVAL 193
E AF S P PA P+ P P S AT L+++P G P PA PA
Sbjct: 791 EEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA-------PA 843
Query: 194 EEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQT 253
+AP +P+++ P + G PR E +G +Q
Sbjct: 844 PASSAPGHVAKLPQKE------PVGCSKGGGPPR-----------EDVGAPLVTPSLLQM 886
Query: 254 ALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPR 313
R + AP+ A G + +P R + V + VR + A
Sbjct: 887 VRLRSVGAPGGAPTPA-LGPSAPQKPLRRALSGRASPVPAPSSGLHAAVRLKACSLAASE 945
Query: 314 PWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPD--------- 364
S + +P P P +S IF + K+Q R P D
Sbjct: 946 GLSSAQPNGPPEAEPRPPQSP-ASTASFIFSKGSRKLQLERPVS-PETQADLQRNLVAEL 1003
Query: 365 RTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSP--WDRTT 422
R++ R P + P P A +P PP +P+ P P N P DRT
Sbjct: 1004 RSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASPSYPRAEPLTAPPTNGLPHTQDRTK 1063
Query: 423 RRVS 426
R ++
Sbjct: 1064 RELA 1067
Score = 47.0 bits (110), Expect = 9e-05
Identities = 109/472 (23%), Positives = 160/472 (33%), Gaps = 95/472 (20%)
Query: 540 GLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLD 599
GL E AP TP APG + + + R P G+ +G
Sbjct: 234 GLRNEREAPGTPRAPGARDAVRIPTVDGR--------------------PRGTSGMGARV 273
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEE 659
+ + E EA +G A+ + R + ++ + G G + L P +
Sbjct: 274 SLQALE----AEAEAGAETEAMLQ-RHIDRVYRDDTFVGRSTGTRAPPLTRPMSLAVPGL 328
Query: 660 GGESKTQEP--PALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLR 717
G + EP PA+ A Y S ++PH P P+ D VA +
Sbjct: 329 TGGAGPAEPLSPAMSISPQATYLS-------KLIPHAVLP--PTVDVVALGRCSLRTL-- 377
Query: 718 RRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTS 777
R +A P +R G + P+ SR + + + +V DG +S
Sbjct: 378 SRCSLHSASP---ASVRSLGRFSSVSSPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSS 434
Query: 778 PLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPR 837
GG+ + S + V P+ GS + SPS G A A R
Sbjct: 435 K-GGSEGQPESSTASNSVVPPPQGGSG--RGSPSGG------------STAEASDTLSIR 479
Query: 838 EPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAP 897
L+GR+ + PP R+ +G A P G + + P+ R + P
Sbjct: 480 SSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGL-----AVPDGPLGLPPKPER---KQQP 531
Query: 898 RQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPG 957
+ PR P +G P P P + L+ G PP P +L PS G
Sbjct: 532 QLPR-----PPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPR---SPERTLSPSSG 583
Query: 958 PQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGK 1009
Y SGTP PP L PP+S G QP K
Sbjct: 584 ----------------------YSSQSGTPT-LPPKGLAGPPASPGKAQPPK 612
>gi|206597543 hypothetical protein LOC118461 isoform 1 [Homo sapiens]
Length = 1435
Score = 83.6 bits (205), Expect = 9e-16
Identities = 115/463 (24%), Positives = 166/463 (35%), Gaps = 71/463 (15%)
Query: 552 SAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP----VGTLDADKCPEVL 607
S P T ++ + + D G S E + P P G+ P VG D K P
Sbjct: 917 STPTNTRGTRVKCMANEVMEDPGQGSSMARMEASQPAPKGNFPSMPLVGEGDRVKAPPDA 976
Query: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAP--GFPAGAQGSGLPAPPADPCGEE---GGE 662
PG AS + D KL + P P G P + C EE G +
Sbjct: 977 APGLVASNCKSGSA----DSGKLAAPWHIPTIALPEGDIEDQPPPWQPENCWEEQTPGFK 1032
Query: 663 SKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQ-PNGVLRRRAE 721
S P GPP S P P P+ + ++SQ P G E
Sbjct: 1033 SHFLSTPRAGPPGRRLVPSERANSPNPGSPGESSACSPAASNIWEESSQAPGGPELLPEE 1092
Query: 722 NSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGG 781
+ A P+ + + RR ++T + G ++ A+ L RT G
Sbjct: 1093 PNQASPWASSS-----PARVTRREDLTHALVWEGGSDPLLELSAEDL------RTLSPRG 1141
Query: 782 ARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQA-------- 833
+ SP G +G R P + AS P + PK + + A+ +
Sbjct: 1142 SLLDVATSPAGTSG-RLELPAQLERTASKPPAVPPKTEKALRRAKKLASKRRKTDQAQEK 1200
Query: 834 --------PLPRE-------PLALAGRTAPAQPRAASAPPT--DRSPQSPSQGARRQPGA 876
P P + PL R P S PP S S+ R+PG
Sbjct: 1201 HGESQEGKPCPEDLEQTQQRPLCPRERPRHNFPVVRSLPPPVHRHSVSGFSEPVGRRPGG 1260
Query: 877 ----APLG------KVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPS----- 921
PL KVL DP+SG Y+ + P Q +++ +DPE+G+YV+V +P S
Sbjct: 1261 PQSLTPLPAYPATQKVLQDPQSGEYFVFDLPLQVKIKTFYDPETGKYVKVSIPSSEGASP 1320
Query: 922 SPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSP 964
P PP + P L P + P+P +L P L +P
Sbjct: 1321 EPPPPDALAAPYVL-----YPGFQPVPVTALMPLRCSSQLSAP 1358
Score = 33.1 bits (74), Expect = 1.4
Identities = 39/158 (24%), Positives = 57/158 (36%), Gaps = 34/158 (21%)
Query: 453 PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP----- 507
PS P++ + ++ ++P AP L VA + S+ S PW P
Sbjct: 959 PSMPLVGEGDRV----KAPPDAAPGL-------VASNCKSGSADSGKLAAPWHIPTIALP 1007
Query: 508 -----DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP------PTPSAPGT 556
D+P W P+ W+ PG F + G L P P P +PG
Sbjct: 1008 EGDIEDQP-PPW--QPENCWEEQTPGFKSHFLSTPRAGPPGRRLVPSERANSPNPGSPGE 1064
Query: 557 PEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHP 594
+ + E S A GG PE+ EP + P
Sbjct: 1065 SSACSPAASNIWEESSQAPGG----PELLPEEPNQASP 1098
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 80.9 bits (198), Expect = 6e-15
Identities = 119/468 (25%), Positives = 152/468 (32%), Gaps = 84/468 (17%)
Query: 462 NQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQET 521
N+ V+ E SPSL A + P +P+ PSPP +P GP PQ
Sbjct: 20 NEDVSQEESPSLIAGNPQGAPPQG---GNKPQGPPSPPG--------KP---QGPPPQGG 65
Query: 522 WDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQS 581
P GP Q + PP P P P P +S S R G Q
Sbjct: 66 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQG 125
Query: 582 P-EVAAPEPPGSHPVGTL-DADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGF 639
+ P PP P G P+ P G P + R R P
Sbjct: 126 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPP 185
Query: 640 PAGAQGSGLPAPPADPCGEEG-GESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPP 698
G Q G P PP P G G +K Q PP G P + P
Sbjct: 186 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP---------------------QGP 224
Query: 699 EPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGG 758
P D ++ A P G + +P P G P+ ++ + P G
Sbjct: 225 PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPP---PPGKPQGPPPQGGNKPQGPPPPG 281
Query: 759 ENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKP 818
+ P G P GG++S S RSP G +P P Q P P P
Sbjct: 282 K----------PQGP---PPQGGSKSRSSRSPPG-------KPQGPPPQGGNQPQGPPPP 321
Query: 819 KTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAP 878
P P P + P P G+ P+ S + RSP QG +Q G P
Sbjct: 322 PGKPQGPPPQGGNKPQGPPPP----GKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNP 377
Query: 879 LGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPP 926
G P G P+QP+ P +GQ P P PP
Sbjct: 378 QGP--PPPAGGN------PQQPQA-----PPAGQ------PQGPPRPP 406
Score = 58.2 bits (139), Expect = 4e-08
Identities = 73/262 (27%), Positives = 87/262 (33%), Gaps = 33/262 (12%)
Query: 770 PDGDGRTSPLGGARSSSQRSPVG-PAGVRSPRPGSPQMQASPSP-----GIAPKPKTPPT 823
P G + P G +S S RSP G P G P G Q Q P P G P+ P
Sbjct: 94 PPGKPQGPPPQGDKSRSPRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQ 151
Query: 824 APEPAAAVQAPLPR-EPLALAGRTAPAQPRA---------ASAPPTDRSPQS-PSQGARR 872
P P Q P P+ + + + R+ P +P+ PP PQ P QG +
Sbjct: 152 GPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 211
Query: 873 QPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTP 932
G P GK P G A P P+ G P P PP + P
Sbjct: 212 PQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQ-----PQGPPPPPGKPQGP 266
Query: 933 LALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPP 992
G G P P PP G S + P GP P P P P
Sbjct: 267 PPQG-GNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKP 325
Query: 993 LLLCAPP-----SSSGPTQPGK 1009
PP GP PGK
Sbjct: 326 Q---GPPPQGGNKPQGPPPPGK 344
Score = 56.6 bits (135), Expect = 1e-07
Identities = 73/274 (26%), Positives = 88/274 (32%), Gaps = 35/274 (12%)
Query: 760 NRDV---EAQRLVPDGDGRTSPLGGARSSSQRSPVG-PAGVRSPRPGSPQMQASPSP--- 812
N DV E+ L+ P GG + SP G P G P G Q Q P P
Sbjct: 20 NEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQG--PPPQGGNQPQGPPPPPGK 77
Query: 813 --GIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRA---------ASAPPTDR 861
G P+ P P P Q P P+ + + R+ P +P+ PP
Sbjct: 78 PQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPG 137
Query: 862 SPQS-PSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPP 920
PQ P QG + G P GK P G + P P+ G P
Sbjct: 138 KPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQ-----PQ 192
Query: 921 SSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYY 980
P PP + P G G P P PP G S + P GP
Sbjct: 193 GPPPPPGKPQGPPPQG-GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGN 251
Query: 981 LPVSGTPNPAPPLLLCAPP-----SSSGPTQPGK 1009
P P P P PP GP PGK
Sbjct: 252 QPQGPPPPPGKPQ---GPPPQGGNKPQGPPPPGK 282
Score = 49.7 bits (117), Expect = 1e-05
Identities = 80/325 (24%), Positives = 105/325 (32%), Gaps = 45/325 (13%)
Query: 359 PREAPDRTVQRARSPPFECRIPSEVPSRAV-RPRSPSPPRQTPNGAVRGPRCPSPQNLSP 417
P+ P + + + PP P P + +P+ P PP + P+ P PQ
Sbjct: 57 PQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGK--------PQGPPPQG--- 105
Query: 418 WDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPS 477
D++ S P P+ P + P PP Q G + P
Sbjct: 106 -DKSRSPRSPPGKPQGPPPQGGNQP-------QGPPPPPGKPQGPPPQGGNKPQGPPPPG 157
Query: 478 LWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEA 537
+ P + + RSS SPP +P GP PQ P GP Q
Sbjct: 158 KPQGPPPQGDN--KSRSSRSPPG--------KP---QGPPPQGGNQPQGPPPPPGKPQGP 204
Query: 538 QNGLTQEELAPPTPSAPGTPEP------TEMQSPSTREISDLAFGGSQ-QSPEVAAPEPP 590
+ PP P P P P +SP + GG+Q Q P P PP
Sbjct: 205 PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP----PPPP 260
Query: 591 GSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPA 650
G P+ P G P + R R P G Q G P
Sbjct: 261 GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPP 320
Query: 651 PPADPCG-EEGGESKTQEPPALGPP 674
PP P G G +K Q PP G P
Sbjct: 321 PPGKPQGPPPQGGNKPQGPPPPGKP 345
Score = 48.9 bits (115), Expect = 2e-05
Identities = 92/420 (21%), Positives = 131/420 (31%), Gaps = 83/420 (19%)
Query: 7 PPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAG 66
PP P+ P P + Q G+ P P P P + P PG+ G
Sbjct: 61 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQG 120
Query: 67 AQPRLSVSAQNSRQRHGPGSGFPRGP-------GSGPRPPQPQLRTLPSGEMEVIFGVGP 119
P+ N Q P G P+GP GP PP P G+ + P
Sbjct: 121 PPPQ----GGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSP 176
Query: 120 LFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPS 179
G + Q P GP P P Q P GG+ +P+GP
Sbjct: 177 PGKPQGPPPQGGNQ-----------PQGPPPPPGKP-QGPPPQGGN--------KPQGPP 216
Query: 180 PAAPAQFECVEVALEEGAA---PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGS 236
P Q + + +A P +P+ P + +PQ PP G P+
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQG---GNQPQGPPPPPGKPQ--------- 264
Query: 237 LDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAK 296
GP P+ P P G P+ +RS+ K +
Sbjct: 265 -----GPPPQGGN----------KPQGPPPP----GKPQGPPPQGGSKSRSSRSPPGKPQ 305
Query: 297 SRPLR--VRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEAR 354
P + + P +P + + P P +P GP Q K + AR
Sbjct: 306 GPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPP-----QGGSKSRSAR 360
Query: 355 K-TRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSP-SPPRQTPNGAVRGPRCPSP 412
P+ P + + PP P P+ P +PP P G R P+ P
Sbjct: 361 SPPGKPQGPPQQEGNNPQGPP---------PPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411
Score = 45.8 bits (107), Expect = 2e-04
Identities = 106/461 (22%), Positives = 148/461 (32%), Gaps = 104/461 (22%)
Query: 39 GSPE--PPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGP 96
G+P+ PP G +GP + PG+ G P Q Q GP P PG P
Sbjct: 34 GNPQGAPPQGGNKPQGPPS----PPGKPQGPPP------QGGNQPQGP----PPPPGK-P 78
Query: 97 RPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISP----LPPGPASPA 152
+ P PQ P G GP G R + +P P P GP P
Sbjct: 79 QGPPPQGGNKPQGPPPPGKPQGP--PPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPP 136
Query: 153 AVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQF---ECVEVALEEGAAPARPRTVPKRQ 209
P Q P GG+ +P+GP P Q + + + P +P+ P +
Sbjct: 137 GKP-QGPPPQGGN--------KPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQG 187
Query: 210 IELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSA 269
+PQ PP G P+ GP P+ P P
Sbjct: 188 ---GNQPQGPPPPPGKPQ--------------GPPPQGGN----------KPQGPPPPGK 220
Query: 270 TFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPA 329
G + + +++ S P K P P + + P
Sbjct: 221 PQGPPPQGDNKSQSA--------------------RSPPGKPQGPPPQGGNQP--QGPPP 258
Query: 330 PGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDR---TVQRARSPPFECRIPSEVPSR 386
P +P GP Q K Q P+ P + + +RSPP + + P P
Sbjct: 259 PPGKPQGPPP-----QGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPP--PQG 311
Query: 387 AVRPRSPSPPRQTPNG-------AVRGPRCP-SPQNLSPWDRTTRRV--SSPLFPEASSE 436
+P+ P PP P G +GP P PQ P + R S P P+ +
Sbjct: 312 GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQ 371
Query: 437 WENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPS 477
E NP + +P P Q R P PS
Sbjct: 372 QEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPS 412
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 79.3 bits (194), Expect = 2e-14
Identities = 221/952 (23%), Positives = 311/952 (32%), Gaps = 210/952 (22%)
Query: 5 LAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPG--SPEPPDV-GPDAKG--------- 52
L PP LP P P P + S T PG S D GP+ KG
Sbjct: 246 LPPPPLPPPPPPPPPPPPPLPGLATSPPFQLTKPGLWSTLHGDAWGPERKGSAPPERQEQ 305
Query: 53 ----PANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRG--PGSGPRPPQPQLRTL 106
P +P+ AP A H PG PG GPRPP +
Sbjct: 306 RHSLPHPYPYPAPAYTA----------------HPPGHRLVPAAPPGPGPRPPGAESH-- 347
Query: 107 PSGEMEVIFGVGPLFGCSGADDREAQ-QQFTEPAFISP------LPPGPASPAAVPRQSQ 159
G P G+D RE++ Q+ + +SP +P P+ P +P
Sbjct: 348 ---------GCLPATRPPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLP--GT 396
Query: 160 VPDGGSRWATYLELRPRGPSPAAPA----QFECVEVALEEGAAPA----------RPRTV 205
S ++ LR P+P P Q +EV+ P+ P
Sbjct: 397 TTSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAAT 456
Query: 206 PKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPA 265
P + L P P SPP P PRLL GP AA +
Sbjct: 457 P--HLSLPPGPSSPP---PPPCPRLLRPPPPPAWLKGPACRAA-----------REDGEI 500
Query: 266 PSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRR 325
FG+ G P + A + +D+ P P P S +
Sbjct: 501 LEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTS----SSNS 556
Query: 326 DKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVP- 384
+ + + P GPVS P R++ PP + P + P
Sbjct: 557 NSGSHSSSPAGPVSFP-----------------PPPYLARSIDPLPRPPSPAQNPQDPPL 599
Query: 385 ---SRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEA-------- 433
+ A+ P PS Q +G+ R P P P RVS P PE
Sbjct: 600 VPLTLALPPAPPSSCHQNTSGSFRRPESPRP-----------RVSFPKTPEVGPGPPPGP 648
Query: 434 -SSEWENQNPAVEETVSRRS-----PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVA 487
S + P V E +R P P+ Q+ + + P A + + S
Sbjct: 649 LSKAPQPVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRK 708
Query: 488 DAVEPRS----SPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQ 543
+ + + +P PP P+ + P T +P T + ++ T TQ
Sbjct: 709 EEEQQQHEAGVAPQPPLKEPFASLQSPFPT-DTAPTTTAPAVAVTTTT--TTTTTTTATQ 765
Query: 544 EELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGS---HPVGTLDA 600
EE P P+ P P + P SQ P P P S L+
Sbjct: 766 EEEKKPPPALPPPPPLAKFPPP------------SQPQPPPPPPPSPASLLKSLASVLEG 813
Query: 601 DK-CPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLP----APPADP 655
K C G G A S RP L T Y+PG P+GA + LP AP A
Sbjct: 814 QKYC--YRGTGAAVSTRP----------GPLPTTQYSPGPPSGA--TALPPTSAAPSAQG 859
Query: 656 CGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGV 715
+ S +Q + GP A ++ +P P +PP P AR S+
Sbjct: 860 SPQPSASSSSQFSTSGGPWARERRAG---EEPVPGPMTPTQPPPPLSLPPARSESEVLEE 916
Query: 716 LRRRAEN----------------STAKPF-KRTEIRLPGALA---LGRRPEVTSRVRARG 755
+ R E TA+P TE LP A A G V+ + R
Sbjct: 917 ISRACETLVERVGRSATDPADPVDTAEPADSGTERLLPPAQAKEEAGGVAAVSGSCKRRQ 976
Query: 756 PGGENRDVEAQRLVPDGDGRTSPLGGARSSSQ------RSPVGPAGVRSPRPGSPQMQAS 809
+ +R D GR G A++ ++ R +G ++S + ++
Sbjct: 977 KEHQKEHRRHRRACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGRE-KSR 1035
Query: 810 PSPGIAPKPK-----TPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASA 856
P G A K K PP+AP P+A P P A AP P + A
Sbjct: 1036 PDLGGASKAKPPTAPAPPSAPAPSAQPTPPSASVPGKKAREEAPGPPGVSRA 1087
Score = 70.1 bits (170), Expect = 1e-11
Identities = 199/864 (23%), Positives = 294/864 (34%), Gaps = 186/864 (21%)
Query: 4 ALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPG-SPEPPDVGPDAKGPANWPWVAPG 62
A +P P + P P SS SS S G P P G D + P
Sbjct: 377 AATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVEPNPGIPGADH-------YQTPA 429
Query: 63 RGAGAQPRLSVSAQNSRQRH------GPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFG 116
RL SA +SR+ P P GP S P PP P+L P +
Sbjct: 430 LEVSHHGRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPPPPPCPRLLRPPPPPAWL--- 486
Query: 117 VGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPR 176
GP C A RE + E F + PP PA P R+ + SR++ +
Sbjct: 487 KGP--ACRAA--REDGEILEELFFGTEGPPRPAPPPLPHREGFLGPPASRFSVGTQDSHT 542
Query: 177 GPSPAAPAQFECVEVALEEGAAPARPRTVP-----KRQIELRPRPQSPPRAAGAPRPRLL 231
P+P P + ++PA P + P R I+ PRP SP A P+
Sbjct: 543 PPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSP-----AQNPQ-- 595
Query: 232 LRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSA---TFGSTGRSE-PETRETARS 287
D L PL A P AP PSS T GS R E P R +
Sbjct: 596 ------DPPLVPLTLAL------------PPAP-PSSCHQNTSGSFRRPESPRPRVSFPK 636
Query: 288 THVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIF---- 343
T V PL +KAP+P P PG L +F
Sbjct: 637 TPEVGPGPPPGPL--------SKAPQPVP-------------PGVGELPARGPRLFDFPP 675
Query: 344 LQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGA 403
E++ +E + + PD + R E +P PP + P +
Sbjct: 676 TPLEDQFEEPAEFKI---LPDGLANIMKMLDESIRKEEEQQQHEAGV-APQPPLKEPFAS 731
Query: 404 VRG--PRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQW 461
++ P +P +P T ++ A+ E E + P P PP L+++
Sbjct: 732 LQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPA-------LPPPPPLAKF 784
Query: 462 NQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTW-GPSPQE 520
P P P + A ++ +S + + + T GP P
Sbjct: 785 ---------PPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTT 835
Query: 521 TWDPMGPGSSIAFTQEAQNGLTQEELAPPT---PSAPGTPEPTEMQSPSTREISDLAFGG 577
+ P P + A PPT PSA G+P+P+ S S + G
Sbjct: 836 QYSPGPPSGATAL--------------PPTSAAPSAQGSPQPSASSS------SQFSTSG 875
Query: 578 SQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAP 637
+ E A E P V GP P +++P R ++++
Sbjct: 876 GPWARERRAGEEP---------------VPGPMTPTQPPPPLSLPPARSESEVLEEISRA 920
Query: 638 GFPAGAQGSGLPAPPADPCG-EEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYE 696
+ PADP E +S T+ L PPA A
Sbjct: 921 CETLVERVGRSATDPADPVDTAEPADSGTER---LLPPAQA------------------- 958
Query: 697 PPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRP-EVTSRVRARG 755
A + +G +RR + K +R R ++GRRP E ++ +A+
Sbjct: 959 ------KEEAGGVAAVSGSCKRR-QKEHQKEHRRH--RRACKDSVGRRPREGRAKAKAKV 1009
Query: 756 PGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIA 815
P ++R R++ + D ++ + G S R +G A P P +P ++P+P
Sbjct: 1010 PKEKSR-----RVLGNLDLQSEEIQGREKS--RPDLGGASKAKP-PTAPAPPSAPAPSAQ 1061
Query: 816 PKPKTPPTAPEPAAAVQAPLPREP 839
P TPP+A P + P P
Sbjct: 1062 P---TPPSASVPGKKAREEAPGPP 1082
Score = 55.5 bits (132), Expect = 3e-07
Identities = 213/940 (22%), Positives = 289/940 (30%), Gaps = 220/940 (23%)
Query: 199 PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
P P +P P P A GAP PR L G L++ G VQ L
Sbjct: 54 PPLPAPLPPSHGSSSGHPSKPYYAPGAPTPRPL---------HGKLESLHGCVQALLREP 104
Query: 259 LSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKS--------------------- 297
P G SE ++ E R H L S
Sbjct: 105 AQPGL----WEQLGQLYESEHDSEEATRCYHSALRYGGSFAELGPRIGRLQQAQLWNFHT 160
Query: 298 ----------RPLRVRDNSAPAKAPRPWPSLR-ERAIRRDKPAPGTEPLGPVSSSIFLQS 346
PL N + R + + R ++R P +P+ P + S
Sbjct: 161 GSCQHRAKVLPPLEQVWNLLHLEHKRNYGAKRGGPPVKRAAEPPVVQPVPPAALS-GPSG 219
Query: 347 EEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPR--------- 397
EE + K R + ++ PP P +P P P PP
Sbjct: 220 EEGLSPGGKRRRGCNS-----EQTGLPPGLPLPPPPLPPPPPPPPPPPPPLPGLATSPPF 274
Query: 398 --------QTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVS 449
T +G G P + +P +R +R S P + +P V
Sbjct: 275 QLTKPGLWSTLHGDAWG---PERKGSAPPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVP 331
Query: 450 RRSPSP---PILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEA 506
P P P ++ + C+ R P + + S + +V P ++ A P+ A
Sbjct: 332 AAPPGPGPRPPGAESHGCLPATRPPGSDLRES-RVQRSRMDSSVSPAAT---TACVPY-A 386
Query: 507 PDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQS-- 564
P RP G G + +S + + + GL E P P A P S
Sbjct: 387 PSRPPGLPGTT-----------TSSSSSSSSNTGLRGVEPNPGIPGADHYQTPALEVSHH 435
Query: 565 ----PSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGP----------- 609
PS G +P ++ P P S P CP +L P
Sbjct: 436 GRLGPSAHSSRKPFLGAPAATPHLSLPPGPSSPP-----PPPCPRLLRPPPPPAWLKGPA 490
Query: 610 -------GE-------AASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADP 655
GE G PR A P P R+ A F G Q S P P P
Sbjct: 491 CRAAREDGEILEELFFGTEGPPRPA-PPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTP 549
Query: 656 C-----GEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYE-PPEPSFD--TVAR 707
G S + P PP P S+ D LP P P + P +P T+A
Sbjct: 550 TTSSSNSNSGSHSSSPAGPVSFPPPPYLARSI---DPLPRPPSPAQNPQDPPLVPLTLAL 606
Query: 708 DASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDV-EAQ 766
+ P+ +T+ F+R E P ++ + PEV GPG + +A
Sbjct: 607 PPAPPSS-----CHQNTSGSFRRPESPRP-RVSFPKTPEV-------GPGPPPGPLSKAP 653
Query: 767 RLVPDGDGRTSPLGGAR----------------SSSQRSPVGPAGVRSPRPGS---PQMQ 807
+ VP G G P G R + + P G A + S + Q
Sbjct: 654 QPVPPGVGEL-PARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQ 712
Query: 808 ASPSPGIAPKP---------------KTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPR 852
G+AP+P T PT PA AV A + +P
Sbjct: 713 QQHEAGVAPQPPLKEPFASLQSPFPTDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPP 772
Query: 853 AASAPPTDRS----PQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDP 908
A PP + P P P A L K L G+ Y
Sbjct: 773 PALPPPPPLAKFPPPSQPQPPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPL 832
Query: 909 ESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQL-- 966
+ QY SPGPP G PP + S SP P A S Q
Sbjct: 833 PTTQY--------SPGPPS--------GATALPPTSA---APSAQGSPQPSASSSSQFST 873
Query: 967 ---PWVSEAGPLDGTYYLPVSGTP-NPAPPLLLCAPPSSS 1002
PW E G +P TP P PPL L PP+ S
Sbjct: 874 SGGPWARERRA--GEEPVPGPMTPTQPPPPLSL--PPARS 909
Score = 35.0 bits (79), Expect = 0.36
Identities = 104/485 (21%), Positives = 155/485 (31%), Gaps = 108/485 (22%)
Query: 2 LTALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAP 61
LT PPA P Q + RR +S S+ P P GP +K P P P
Sbjct: 602 LTLALPPAPPSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAPQPVP---P 658
Query: 62 GRG--AGAQPRL----------------------------------SVSAQNSRQRHGPG 85
G G PRL S+ + +Q+H G
Sbjct: 659 GVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQQQHEAG 718
Query: 86 SGFPRGPGSGP----RPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFI 141
P+ P P + P P T P+ + + + +++ PA
Sbjct: 719 VA-PQPPLKEPFASLQSPFP-TDTAPTTTAPAVAVTTTTTTTTTTTATQEEEKKPPPAL- 775
Query: 142 SPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEG----- 196
PP P + P Q Q P P P +PA ++ EG
Sbjct: 776 --PPPPPLAKFPPPSQPQPPP---------------PPPPSPASLLKSLASVLEGQKYCY 818
Query: 197 -----AAPARPRTVPKRQIE--------LRPRPQSPPRAAGAPRPRLLLRTGSLDESLGP 243
A RP +P Q P + P A G+P+P + S GP
Sbjct: 819 RGTGAAVSTRPGPLPTTQYSPGPPSGATALPPTSAAPSAQGSPQPS-ASSSSQFSTSGGP 877
Query: 244 LQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPET-RETARSTHVVLEKAKSRPLRV 302
+ + ++P P P + RSE E E +R+ ++E+
Sbjct: 878 WARERRAGEEPVPGPMTPTQPPPPLSL--PPARSESEVLEEISRACETLVERVGR---SA 932
Query: 303 RDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLG---PVSSSIFLQSEEKIQEARKTRFP 359
D + P P S ER + PA E G VS S + +E +E R+ R
Sbjct: 933 TDPADPVDTAEPADSGTERLL---PPAQAKEEAGGVAAVSGSCKRRQKEHQKEHRRHR-- 987
Query: 360 REAPDRTVQRARS--PPFECRIPSE----------VPSRAVRPRSPSPPRQTPNGAVRGP 407
R D +R R + ++P E + S ++ R S P + P
Sbjct: 988 RACKDSVGRRPREGRAKAKAKVPKEKSRRVLGNLDLQSEEIQGREKSRPDLGGASKAKPP 1047
Query: 408 RCPSP 412
P+P
Sbjct: 1048 TAPAP 1052
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 74.3 bits (181), Expect = 5e-13
Identities = 169/746 (22%), Positives = 229/746 (30%), Gaps = 220/746 (29%)
Query: 302 VRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPRE 361
++ S+ + P S + + D T+P G V S + S R T+
Sbjct: 534 IKSGSSSSSIPE---SQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEES 590
Query: 362 APDRTVQRARS-----PPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLS 416
+ R R PP + P A +P P PP P P P P L
Sbjct: 591 SKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLP 650
Query: 417 PWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAP 476
+ ++P+F + S+ QN + + P+PP++ +Q V P + P
Sbjct: 651 SQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQ--SQSV----KPQILVP 704
Query: 477 SLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQE 536
+ V P P PP P PGS++A +
Sbjct: 705 ----------PNGVVPPPPPPPP------------------------PPTPGSAMAQLK- 729
Query: 537 AQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVG 596
P P AP P+ + P L Q +VA P PP P+
Sbjct: 730 ------------PAPCAPSLPQFSAPPPP-------LKIHQVQHITQVAPPTPPPPPPI- 769
Query: 597 TLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPC 656
P L P A +P + IP P + T AP A + P PP P
Sbjct: 770 -------PAPLPP--QAPPKPLVTIPAPTSTK-----TVAPVVTQAAPPT--PTPPVPPA 813
Query: 657 GEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPV-VPHPYEPPEPSFDTVARDASQPNGV 715
++ + PP+ PP P PV VP P P + SF
Sbjct: 814 KKQPAFPASYIPPS--PPTP------------PVPVPPPTLPKQQSF------------- 846
Query: 716 LRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGR 775
AK P L P V ++ ++ P
Sbjct: 847 --------CAK---------PPPSPLSPVPSVVKQIASQFP------------------- 870
Query: 776 TSPLGGARSSSQRSPVGPAGVRSPRP----GSPQMQASPSPGIAPKPKTPPTAPEPAAAV 831
P A S PV PA V P P+ Q S P P P PP PE ++ V
Sbjct: 871 PPPTPPAMESQPLKPV-PANVAPQSPPAVKAKPKWQPSSIP--VPSPDFPPPPPE-SSLV 926
Query: 832 QAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSP-------SQGARRQPGAAPLGKVLV 884
P P P+ AP P +A PT SP S ++P P +
Sbjct: 927 FPPPPPSPV-----PAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI 981
Query: 885 DPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAY 944
SG E P R P V PP+ G P + P PPA
Sbjct: 982 KSSSG----AEHPEPKR------PSVDSLVSKFTPPAESGSPSKETLP--------PPA- 1022
Query: 945 GPIPSLSLPPSPGPQALGSPQLPWVSEAG-----------------------PLDGTYYL 981
PP PG L LP V + G P D +
Sbjct: 1023 -------APPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPP 1075
Query: 982 PVSGTPNPAPPLLLCAPPSSSGPTQP 1007
P T P PP+ + P SG T P
Sbjct: 1076 PPPETELPLPPIEI--PAVFSGNTSP 1099
Score = 53.1 bits (126), Expect = 1e-06
Identities = 145/645 (22%), Positives = 204/645 (31%), Gaps = 132/645 (20%)
Query: 55 NWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVI 114
N P+ + QP++ V+ + Q P P P P PP P LPS
Sbjct: 599 NRPYTSLVPPLSPQPKI-VTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 115 FGVGPLFGCSGADDR-EAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLEL 173
P+F R + Q + F P PP S + P Q VP
Sbjct: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKP-QILVP------------ 704
Query: 174 RPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSP--PRAAGAPRPRLL 231
P G P P P P T +L+P P +P P+ + P P +
Sbjct: 705 -PNGVVPPPP--------------PPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749
Query: 232 LRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVV 291
+ + + P + L P+AP T P T VV
Sbjct: 750 HQVQHITQVAPPTPPP----PPPIPAPLPPQAPPKPLVTI-------PAPTSTKTVAPVV 798
Query: 292 LEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQ 351
+ A P + P + P+ I P+P T P+ PV
Sbjct: 799 TQAAPPTP------TPPVPPAKKQPAFPASYI---PPSPPTPPV-PVP------------ 836
Query: 352 EARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPS 411
P P + A+ PP S VPS + S PP TP P P
Sbjct: 837 -------PPTLPKQQSFCAKPPPSPL---SPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886
Query: 412 PQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSP 471
P N++P SP +A +W+ + V PSP P
Sbjct: 887 PANVAP--------QSPPAVKAKPKWQPSSIPV--------PSPDF-----------PPP 919
Query: 472 SLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMG--PGS 529
E+ ++ P + A P P PP P PD+ G+ G +T P G P
Sbjct: 920 PPESSLVFPPPPPSPVPAPPP---PPPPTASP--TPDKS-GSPGKKTSKTSSPGGKKPPP 973
Query: 530 SIAFTQEAQNGLTQEELAPPTPSAPG-----TPEPTEMQSPSTREISDLAFGGSQQSPEV 584
+ ++ E P PS TP P E SPS + P
Sbjct: 974 TPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTP-PAESGSPSKETL-----------PPP 1021
Query: 585 AAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQ 644
AAP PG L P VL G ++ P ++ V + FP
Sbjct: 1022 AAPPKPGKL---NLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPP 1078
Query: 645 GSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLP 689
+ LP PP + G T A+ P P ++ + +K P
Sbjct: 1079 ETELPLPPIEIPAVFSG--NTSPKVAVVNPQPQQWSKMSVKKAPP 1121
Score = 49.7 bits (117), Expect = 1e-05
Identities = 88/385 (22%), Positives = 126/385 (32%), Gaps = 89/385 (23%)
Query: 665 TQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENST 724
+Q P L PP P P P P PP P ++ A + ST
Sbjct: 622 SQPSPPLPPPPP------------PPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYST 669
Query: 725 AKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPL----- 779
+ + GAL P V +++ V+ Q LVP P
Sbjct: 670 ITRLQNAS-QHSGALFKPPTPPVM----------QSQSVKPQILVPPNGVVPPPPPPPPP 718
Query: 780 ---GGARSSSQRSPVGPAGVRSPRPGSP----QMQ--------ASPSPGIAPKPKTPPTA 824
G A + + +P P+ + P P Q+Q P P P P P
Sbjct: 719 PTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAP 778
Query: 825 PEPAAAVQAPLPREPLA-LAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVL 883
P+P + AP + +A + + AP P PP + + P+ A P + P V
Sbjct: 779 PKPLVTIPAPTSTKTVAPVVTQAAPPTP----TPPVPPAKKQPAFPASYIPPSPPTPPVP 834
Query: 884 VDPES---GRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPL------- 933
V P + + + + P P V P + + PP P PP PL
Sbjct: 835 VPPPTLPKQQSFCAKPPPSPLSPV---PSVVKQIASQFPPP-PTPPAMESQPLKPVPANV 890
Query: 934 -------ALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGT 986
+ P+ P+PS PP P +L P P S
Sbjct: 891 APQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP---------------PSPV 935
Query: 987 PNPAPPLLLCAPPSSSGPTQPGKGS 1011
P P PP PP ++ PT GS
Sbjct: 936 PAPPPP-----PPPTASPTPDKSGS 955
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 72.0 bits (175), Expect = 3e-12
Identities = 156/711 (21%), Positives = 229/711 (32%), Gaps = 143/711 (20%)
Query: 280 ETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKP----APGTEPL 335
E H V+E ++ + V + KAP P + E+ I KP P EP
Sbjct: 10410 EEEHRVEKVHRVIEVFEAEEVEVFEKP---KAPPKGPEISEKIIPPKKPPTKVVPRKEPP 10466
Query: 336 GPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSP 395
V + +KI K R P E R PP ++P +P P+ P
Sbjct: 10467 AKVP-----EVPKKIVVEEKVRVPEEP--------RVPP--TKVPEVLP-----PKEVVP 10506
Query: 396 PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSP 455
++ P + P P P+ PEA E V E ++ P P
Sbjct: 10507 EKKVPVPPAKKPEAPPPK----------------VPEAPKE------VVPE---KKVPVP 10541
Query: 456 PILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWG 515
P + P + + E+P +AV + P + P P P E P+ P
Sbjct: 10542 P-----------PKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVP 10590
Query: 516 PSPQETWDPMGPGSSIAFTQEAQNGLTQEELAP-PTPSAPGTPEPTEMQSPSTREISDLA 574
P P + EA + E+ P P P P P PT++
Sbjct: 10591 EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP-PTKV------------ 10637
Query: 575 FGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTT 634
+ P+VA PE K PE + P P P +V
Sbjct: 10638 ----PEVPKVAVPE------------KKVPEAIPP--KPESPPPEVFEEPEEVALEEPPA 10679
Query: 635 YAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGP-PAPAHYTSVFIKDFLP-VVP 692
P A + PP P E+ + + P L P P V + +P VVP
Sbjct: 10680 EVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVP 10739
Query: 693 HPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVR 752
E P V ++ V + P K E+ P L +P V R
Sbjct: 10740 KKPEAPPAKVPEVPKEVVPEKKV--AVPKKPEVPPAKVPEV--PKKPVLEEKPAVPVPER 10795
Query: 753 ARGPGGENRDVEAQRLVPDGD---GRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQAS 809
A P E + E + + P+ + P+ A P PA P+ P+ +
Sbjct: 10796 AESPPPEVYE-EPEEIAPEEEIAPEEEKPVPVAEEEEPEVP-PPAVPEEPKKIIPEKKV- 10852
Query: 810 PSPGIAPKPKTPPTAPEPAAAVQAP--LPREPLALAGRTAPAQPRAASAPPTDRSPQSPS 867
P I PP PEP ++ P PR P PP P+
Sbjct: 10853 --PVIKKPEAPPPKEPEPEKVIEKPKLKPRPP-----------------PPPPAPPKEDV 10893
Query: 868 QGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPH 927
+ Q A P KV P + P + L L P + V LLP P P
Sbjct: 10894 KEKIFQLKAIPKKKVPEKP--------QVPEKVELTPLKVPGGEKKVRKLLPERKPEPKE 10945
Query: 928 RVYTPLALGL-------GLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSE 971
V L + P + ++P P P+ + ++P V++
Sbjct: 10946 EVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTK 10996
Score = 58.5 bits (140), Expect = 3e-08
Identities = 128/579 (22%), Positives = 196/579 (33%), Gaps = 110/579 (18%)
Query: 148 PASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAP-AQFECVEVALEEGAAPARPRTVP 206
P P A + +VP+ + +P P P P A E V A P +P P
Sbjct: 10554 PEVPKAAVPEKKVPEA-------IPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTP 10606
Query: 207 KRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAP 266
+ E P+ P + P P+ + P + A+ K PEA P
Sbjct: 10607 VKVPE-APKEVVPEKKVPVPPPK---------KPEVPPTKVPEVPKVAVPEKKVPEAIPP 10656
Query: 267 SSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKA----PRPWPSLRERA 322
+ EPE V LE+ + + + +AP + +P P + A
Sbjct: 10657 KPESPPPEVFEEPE--------EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPA 10708
Query: 323 IRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFP-REAPDRTVQRARSPPFECRIPS 381
+ KP L PV K+ E K P ++ P ++ +PP ++P
Sbjct: 10709 VVAKKP-----ELPPV----------KVPEVPKEVVPEKKVPLVVPKKPEAPP--AKVP- 10750
Query: 382 EVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNL--SPWDRTTRRVSSPLFPEASSEWEN 439
EVP V + + P++ + P P L P R SP PE E E
Sbjct: 10751 EVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP-PEVYEEPEE 10809
Query: 440 QNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEP--RSSPS 497
P E P P VA E P + P++ E P + + P + +
Sbjct: 10810 IAPEEEIAPEEEKPVP---------VAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEA 10860
Query: 498 PPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTP 557
PP P P++ I P+ P P + Q ++ P P P
Sbjct: 10861 PPPKEP--EPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKV 10918
Query: 558 EPTEMQSP----STREI---------------SDLAFGGSQQSPEV-----------AAP 587
E T ++ P R++ S L ++ P+V A P
Sbjct: 10919 ELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVP 10978
Query: 588 EPPGSHPVGTLDAD-------KCPEVLGPGEAASGRPRMAIPRPRDVRK---LVKTTYAP 637
EPP PV ++ K PE P + +P + +P P K VKT P
Sbjct: 10979 EPPPPKPVEEVEVPTVTKRERKIPE---PTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPP 11035
Query: 638 GFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAP 676
P + + + AP P + E+K + A P P
Sbjct: 11036 --PVEPEPTPIAAPVTVPVVGKKAEAKAPKEEAAKPKGP 11072
Score = 54.3 bits (129), Expect = 6e-07
Identities = 168/772 (21%), Positives = 249/772 (32%), Gaps = 153/772 (19%)
Query: 144 LPPGPASPAAVPRQ---SQVPDGGSRWATYLELR----PRGPSPAAPAQFECVEVALEEG 196
+PP VPR+ ++VP+ + ++R PR P P EV E+
Sbjct: 10450 IPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKK 10509
Query: 197 ----------AAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQA 246
A P + PK + + P PP+ P ++
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKV---------------- 10553
Query: 247 AAGFVQTALARKLSPEA--PAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRD 304
+ A+ K PEA P P S PE E + VV EK +
Sbjct: 10554 -PEVPKAAVPEKKVPEAIPPKPES--------PPPEVPEAPK--EVVPEKKVPAAPPKKP 10602
Query: 305 NSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFP-REAP 363
P K P + + +K P P P K+ E K P ++ P
Sbjct: 10603 EVTPVKVPE-----APKEVVPEKKVPVPPPKKPE------VPPTKVPEVPKVAVPEKKVP 10651
Query: 364 DRTVQRARSPPFEC-RIPSEV-----PSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSP 417
+ + SPP E P EV P+ V P+ P Q P+ P P+ +P
Sbjct: 10652 EAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQ----VTVPPKKPVPEKKAP 10707
Query: 418 WDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPS 477
P P + E+ V P P +P + P
Sbjct: 10708 ----AVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKP------------EAPPAKVP- 10750
Query: 478 LWEIPHSAVAD--AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQ 535
E+P V + P+ PPA P E P +P+ P+ P A +
Sbjct: 10751 --EVPKEVVPEKKVAVPKKPEVPPAKVP-EVPKKPVLEEKPAV--------PVPERAESP 10799
Query: 536 EAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPV 595
+ EE+AP AP +P + ++ PEV P P P
Sbjct: 10800 PPEVYEEPEEIAPEEEIAPEEEKPVPV--------------AEEEEPEVPPPAVP-EEPK 10844
Query: 596 GTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADP 655
+ K P + P EA P P P V + K P P PAPP +
Sbjct: 10845 KIIPEKKVPVIKKP-EA----PPPKEPEPEKVIEKPKLKPRPPPPP-------PAPPKED 10892
Query: 656 CGEE----GGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPH--PYEPPEPSFDTVARDA 709
E+ K + P P T + + V P PEP + V +
Sbjct: 10893 VKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLK-- 10950
Query: 710 SQPNGVLRRRAENSTAK--PFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQR 767
VLR+R E K P K +++ P A+ P+ V R +
Sbjct: 10951 ----SVLRKRPEEEEPKVEPKKLEKVKKP-AVPEPPPPKPVEEVEVPTVTKRERKIPEPT 11005
Query: 768 LVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEP 827
VP+ PL + + P A V++ +P P ++ P+P A P T P
Sbjct: 11006 KVPE-IKPAIPL----PAPEPKPKPEAEVKTIKP--PPVEPEPTPIAA-----PVTVPVV 11053
Query: 828 AAAVQAPLPREPLALAGRTAPAQPRAASAP-PTDRSPQSPSQGARRQPGAAP 878
+A P+E A P+ +P +R P G + P AP
Sbjct: 11054 GKKAEAKAPKEEAAKPKGPIKGVPKKTPSPIEAERRKLRPGSGGEKPPDEAP 11105
Score = 50.8 bits (120), Expect = 6e-06
Identities = 168/845 (19%), Positives = 273/845 (32%), Gaps = 121/845 (14%)
Query: 175 PRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIE----LRPRPQSPPRAAGAPRPRL 230
P P P + + V V ++ A PA+ VPK+ E L P+ + PP A P+
Sbjct: 9951 PEVPRKPVPEEKKPVPVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKK 10010
Query: 231 LLRTGSLDESLGPLQAAAGFVQTALARKLSPE--APAPSSATFGSTGRSEPETRE----T 284
+ + + A + +K PE P P+ + PE +
Sbjct: 10011 PVPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPE 10070
Query: 285 ARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPS-----LRERAIRRDKPAPGTEPLGPVS 339
+ V +K ++ P +V P P P E + ++ P E + P
Sbjct: 10071 EKKPTPVPKKVEAPPPKVPKKREPVPVPVALPQEEEVLFEEEIVPEEEVLPEEEEVLPEE 10130
Query: 340 SSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSP---- 395
+ + EE + E + P E + + P E +P E V+P+ P P
Sbjct: 10131 EEVLPEEEEVLPE--EEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVP 10188
Query: 396 -------------PRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNP 442
P++ + P P R + P +E + P
Sbjct: 10189 EIKKKVTEKKVVIPKKEEAPPAKVPEVPKKVEEK---RIILPKEEEVLPVEVTEEPEEEP 10245
Query: 443 AVEETVSRRSPSPPILSQWNQCVAGERSPSL----------EAPSLWEIPHSAVADAVEP 492
EE + PS + + VA R P + P E P + V+ +
Sbjct: 10246 ISEEEIPEEPPSIEEVEE----VAPPRVPEVIKKAVPEAPTPVPKKVEAPPAKVSKKIPE 10301
Query: 493 RSSP-------SPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGS-------SIAFTQEAQ 538
P +PPA P E P + P++ P G S+AF QE
Sbjct: 10302 EKVPVPVQKKEAPPAKVP-EVPKKVPEKKVLVPKKEAVPPAKGRTVLEEKVSVAFRQEV- 10359
Query: 539 NGLTQEELAPPTPSAPGTPEPTEMQSPSTRE-ISDLAFGGSQQSPEVAAPEPPGSHPVGT 597
+ +E L A P E + E + F ++ ++ H V
Sbjct: 10360 --VVKERLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRV-- 10415
Query: 598 LDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCG 657
+K V+ EA + ++ + AP P G + S PP P
Sbjct: 10416 ---EKVHRVIEVFEA-------------EEVEVFEKPKAP--PKGPEISEKIIPPKKPPT 10457
Query: 658 EEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLR 717
+ +EPPA P P + +++ + V P PP T + P V+
Sbjct: 10458 K---VVPRKEPPAKVPEVP---KKIVVEEKVRVPEEPRVPP-----TKVPEVLPPKEVVP 10506
Query: 718 RRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTS 777
+ P K+ E P + EV + P + +V + VP+
Sbjct: 10507 EK--KVPVPPAKKPEAPPPKVPEAPK--EVVPEKKVPVPPPKKPEVPPTK-VPEVPKAAV 10561
Query: 778 PLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPK--PKTPPTAPEPAAAVQAPL 835
P V A P P++ +P + K P PP PE
Sbjct: 10562 P---------EKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEA 10612
Query: 836 PREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGA--RRQPGAAPLGKVLVDPESGRYYF 893
P+E + + P P P + P+ P ++ P A P PE
Sbjct: 10613 PKE--VVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPE 10670
Query: 894 VEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLP 953
A +P V+ +PE +V +PP P P + +A L P +P +P
Sbjct: 10671 EVALEEPPAEVVEEPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVP 10730
Query: 954 PSPGP 958
P
Sbjct: 10731 EKKVP 10735
Score = 33.9 bits (76), Expect = 0.80
Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 5/84 (5%)
Query: 799 PRPGSPQMQASPSPG-IAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAP 857
P P P++ P+P +AP P P EP A +P++P+ + P + +AP
Sbjct: 9284 PPPKVPELPEKPAPEEVAPVPI--PKKVEPPAPKVPEVPKKPVPEEKKPVPVPKKEPAAP 9341
Query: 858 PTDRSPQSPSQGARRQPGAAPLGK 881
P + P+ P + + P+ K
Sbjct: 9342 P--KVPEVPKKPVPEEKIPVPVAK 9363
Score = 32.0 bits (71), Expect = 3.0
Identities = 36/156 (23%), Positives = 59/156 (37%), Gaps = 21/156 (13%)
Query: 337 PVSSSIFLQSEEKIQEARKTRFPREAP-----------DRTVQRARSPPFECRIPSEVPS 385
P + + S +I E+R+TR ++ + + A + P +P
Sbjct: 200 PAKKTKTIVSTAQISESRQTRIEKKIEAHFDARSIATVEMVIDGAAGQQLPHKTPPRIPP 259
Query: 386 RAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVE 445
+ + RSP+PP + + PSP SP R V +P S + +PA
Sbjct: 260 KP-KSRSPTPPSIAAKAQLARQQSPSPIRHSP--SPVRHVRAP----TPSPVRSVSPAAR 312
Query: 446 ETVSR-RSPSPPILSQWNQCVAGERSPSLEAPSLWE 480
+ S RS P+L + Q P E P W+
Sbjct: 313 ISTSPIRSVRSPLLMRKTQASTVATGP--EVPPPWK 346
Score = 32.0 bits (71), Expect = 3.0
Identities = 30/115 (26%), Positives = 43/115 (37%), Gaps = 8/115 (6%)
Query: 174 RPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLR 233
+P+ SP P+ ++A ++ +P R P R + P P SP R+ P +
Sbjct: 260 KPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVR-APTP-SPVRSVS---PAARIS 314
Query: 234 TGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARST 288
T + PL T PE P P SE E RET +T
Sbjct: 315 TSPIRSVRSPLLMRKTQASTVAT---GPEVPPPWKQEGYVASSSEAEMRETTLTT 366
Score = 30.4 bits (67), Expect = 8.8
Identities = 23/75 (30%), Positives = 29/75 (38%), Gaps = 8/75 (10%)
Query: 805 QMQASPSPGIAPKPKT-PPTAPEPAAAVQ-------APLPREPLALAGRTAPAQPRAASA 856
Q+ P I PKPK+ PT P AA Q +P+ P + AP S
Sbjct: 248 QLPHKTPPRIPPKPKSRSPTPPSIAAKAQLARQQSPSPIRHSPSPVRHVRAPTPSPVRSV 307
Query: 857 PPTDRSPQSPSQGAR 871
P R SP + R
Sbjct: 308 SPAARISTSPIRSVR 322
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 71.6 bits (174), Expect = 3e-12
Identities = 208/887 (23%), Positives = 296/887 (33%), Gaps = 210/887 (23%)
Query: 143 PLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARP 202
PLPP P SPA P + P E P A+++ V A++EGAA
Sbjct: 1851 PLPPAPLSPAPGP-PTPAP----------ESHTPAPFSWGTAEYDSVVAAVQEGAA---- 1895
Query: 203 RTVPKRQIELRPRPQSPP----RAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
EL P SP R A R E G +A +++ + K
Sbjct: 1896 --------ELEGGPYSPLGKDYRKAEGER-----------EEEGRAEAPD---KSSHSSK 1933
Query: 259 LSPEAPAPSSATFGSTGRSEPETRETA-----RSTHV--VLEKAKSRPL--RVRDNSAPA 309
+ PEA + T ++EPE RE RS + E+ L P
Sbjct: 1934 V-PEASKSHATT--EPEQTEPEQREPTPYPDERSFQYADIYEQMMLTGLGPACPTREPPL 1990
Query: 310 KAPRPWP---SLRERAIRRDKPAPG--TEPLGPVSSSIFLQSEEKIQEARKTRFPREAPD 364
A WP S +E A R+ A + P+ P S + A T PR P
Sbjct: 1991 GAAGDWPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSDTPTFSYAALAGPTVPPRPEPG 2050
Query: 365 RTVQRARSPPFECRIPSEVPSRA-VRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTR 423
+++ + +PP VP RA + + PSPP NG + C SP SP + +
Sbjct: 2051 PSMEPSLTPP-------AVPPRAPILSKGPSPPL---NGNILS--C-SPDRRSPSPKESG 2097
Query: 424 RVSSPLFPEASSEWENQNPAVEETVSR-RSPSPPILSQWNQCVAGERSPSLEAPSLWEIP 482
R + +++S+ E + A E+ +SPSPP + +P+LW
Sbjct: 2098 RSH---WDDSTSDSELEKGAREQPEKEAQSPSPP------------HPIPMGSPTLWPET 2142
Query: 483 HSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWG-----PSPQETWDPMGPGS----SIAF 533
+ V+ ++ P+ P+ D P +G P+P + P P S S+AF
Sbjct: 2143 EAHVSPPLDSHLGPARPSL------DFPASAFGFSSLQPAPPQLPSPAEPRSAPCGSLAF 2196
Query: 534 TQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSH 593
+ G LAP P+ E E+ + + S P++ +P PG+
Sbjct: 2197 S-----GDRALALAPGPPTRTRHDEYLEVTKAPSLDSS---------LPQLPSPSSPGAP 2242
Query: 594 PVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPA 653
+ L P + + + P V V ++P A Q SG
Sbjct: 2243 LLSNLPRPASPALSEGSSSEATTP---------VISSVAERFSPSLEAAEQESG----EL 2289
Query: 654 DPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPN 713
DP E S P L P PA L + P P P + +
Sbjct: 2290 DPGMEPAAHSLWDLTP-LSPAPPASLD-------LALAPAPSLPGDMG-----------D 2330
Query: 714 GVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGD 773
G+L E S A K + ++P P TS GP + E P +
Sbjct: 2331 GILPCHLECSEAATEKPSPFQVPSEDCAANGPTETSP-NPPGPAPAKAENEEAAACPAWE 2389
Query: 774 GRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEP------ 827
P G RSS + + P P GS +S SP + P+ T P P
Sbjct: 2390 RGAWPEGAERSSRPDTLLSPEQPVCPAGGSGGPPSSASPEVEAGPQGCATEPRPHRGELS 2449
Query: 828 AAAVQAPLP---------REPLALAGR-----------TAPAQPRAASAPPTDRSPQSPS 867
+ + PLP E + L GR T P PPT S S
Sbjct: 2450 PSFLNPPLPPSIDDRDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSS 2509
Query: 868 QGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPH 927
Q P PE+ E P L E G ++ V G H
Sbjct: 2510 QSDSDVP-----------PET-----EECPSITAEAALDSDEDGDFLPVDKAGGVSGTHH 2553
Query: 928 RVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGP 974
P P PP P P SP P V A P
Sbjct: 2554 ------------------PRPGHDPPPLPQPDPRPSPPRPDVCMADP 2582
Score = 60.8 bits (146), Expect = 6e-09
Identities = 166/692 (23%), Positives = 228/692 (32%), Gaps = 143/692 (20%)
Query: 192 ALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFV 251
AL P RP P + L P P PPRA P L S GP G +
Sbjct: 2037 ALAGPTVPPRPEPGPSMEPSLTP-PAVPPRA-----PIL---------SKGPSPPLNGNI 2081
Query: 252 QTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKA 311
+ + SP +P S + S+ E + AR ++ S P + P +
Sbjct: 2082 LSCSPDRRSP-SPKESGRSHWDDSTSDSELEKGAREQPEKEAQSPSPP-----HPIPMGS 2135
Query: 312 PRPWPSLRERAIRRDKPAPGTEPLGPVSSSI--------FLQSEEKIQEARKTRFPREAP 363
P WP P LGP S+ F + + PR AP
Sbjct: 2136 PTLWPETEAHV-----SPPLDSHLGPARPSLDFPASAFGFSSLQPAPPQLPSPAEPRSAP 2190
Query: 364 --------DRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNL 415
DR + A PP R E P S Q P+ + P P NL
Sbjct: 2191 CGSLAFSGDRALALAPGPPTRTR-HDEYLEVTKAPSLDSSLPQLPSPS--SPGAPLLSNL 2247
Query: 416 SPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLE- 474
R +SP E SS E P + R SPS Q +GE P +E
Sbjct: 2248 P-------RPASPALSEGSSS-EATTPVISSVAERFSPSLEAAEQ----ESGELDPGMEP 2295
Query: 475 -APSLWEI------PHSAVADAVEPRSSPSPPAFF--------------------PWEAP 507
A SLW++ P +++ A+ P +PS P P++ P
Sbjct: 2296 AAHSLWDLTPLSPAPPASLDLALAP--APSLPGDMGDGILPCHLECSEAATEKPSPFQVP 2353
Query: 508 DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPST 567
GP+ + + +P GP + A +EA E A P A + P + SP
Sbjct: 2354 SEDCAANGPT-ETSPNPPGPAPAKAENEEAAACPAWERGAWPE-GAERSSRPDTLLSP-- 2409
Query: 568 REISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDV 627
E GGS P A+PE P G + GE + +P D
Sbjct: 2410 -EQPVCPAGGSGGPPSSASPEVEAG-PQGCATEPRPHR----GELSPSFLNPPLPPSIDD 2463
Query: 628 RKLVKTTYAPGFPAGAQGSGLPAPPADPC----------GEEGGESK--------TQEPP 669
R L G + G P PC + G S+ T+E P
Sbjct: 2464 RDLSTEEVRLVGRGGRRRVGGPGTTGGPCPVTDETPPTSASDSGSSQSDSDVPPETEECP 2523
Query: 670 ALGPPAPAHYTSVFIKDFLPVV----------PHPYEPPEPSFDTVARDASQPNGVLRRR 719
++ A A S DFLPV P P P P R + V
Sbjct: 2524 SI--TAEAALDSDEDGDFLPVDKAGGVSGTHHPRPGHDPPPLPQPDPRPSPPRPDVCMAD 2581
Query: 720 AENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPL 779
E +++ + +R + +V RV R PG A+RL D G+ SP
Sbjct: 2582 PEGLSSESGRVERLR--------EKEKVQGRVGRRAPGKAKPASPARRL--DLRGKRSPT 2631
Query: 780 GGARSSSQRSPVGPAGVRSPRPGSPQMQASPS 811
G + P A PRP S Q +P+
Sbjct: 2632 PG------KGPADRASRAPPRPRSTTSQVTPA 2657
Score = 49.7 bits (117), Expect = 1e-05
Identities = 140/637 (21%), Positives = 199/637 (31%), Gaps = 151/637 (23%)
Query: 436 EWENQNPAVEETVSRRSPSPPILS-----QWNQCVAGERSPSLEAPSLWE---------I 481
EW+ +P EE + P Q N+ G +LE + W
Sbjct: 1649 EWQETSPTREEPAGEQKELAPAWEDTSPEQDNRYWRGREDVALEQDTYWRELSCERKVWF 1708
Query: 482 PHSAVADAVEPRSSPSPPAFFPWEAPD-------RPIGTWGP-----------SPQ---- 519
PH P + + F E PD R T P SPQ
Sbjct: 1709 PHELDGQGARPHYTEERESTFLDEGPDDEQEVPLREHATRSPWASDFKDFQESSPQKGLE 1768
Query: 520 -ETWDPMGPGSSIAFTQEAQNGLTQ---EELAPPT----------PSAPGTPEPTEMQSP 565
E W P + E ++ LT+ E ++PP PSAPG P P
Sbjct: 1769 VERWLAESP---VGLPPEEEDKLTRSPFEIISPPASPPEMVGQRVPSAPGQESPI----P 1821
Query: 566 STREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPR 625
+ + + +P A PP L GP A P P P
Sbjct: 1822 DPKLMPHMK--NEPTTPSWLADIPPWVPKDRPLPPAPLSPAPGPPTPA---PESHTPAPF 1876
Query: 626 DVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGES---KTQEPPALGPPAPAHYTSV 682
+ GA + L P P G++ ++ + +E A P +H + V
Sbjct: 1877 SWGTAEYDSVVAAVQEGA--AELEGGPYSPLGKDYRKAEGEREEEGRAEAPDKSSHSSKV 1934
Query: 683 FIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALG 742
PE S + Q R + F+ +I + G
Sbjct: 1935 ---------------PEASKSHATTEPEQTEPEQREPTPYPDERSFQYADI-YEQMMLTG 1978
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQR---SPVGPAGVRSP 799
P +R G G+ P G +S+++ SP+ P ++S
Sbjct: 1979 LGPACPTREPPLGAAGD---------WPPCLSTKEAAAGRNTSAEKELSSPISPKSLQSD 2029
Query: 800 RPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPT 859
P + A P + P+P+ P+ EP+ A PR P+ G + P S P
Sbjct: 2030 TP-TFSYAALAGPTVPPRPEPGPSM-EPSLTPPAVPPRAPILSKGPSPPLNGNILSCSPD 2087
Query: 860 DRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLP 919
RSP SP ESGR ++ ++ L E G +
Sbjct: 2088 RRSP-SPK-------------------ESGRSHWDDSTSDSEL------EKGAREQPEKE 2121
Query: 920 PSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTY 979
SP PPH PIP S P +A SP P S GP +
Sbjct: 2122 AQSPSPPH------------------PIPMGSPTLWPETEAHVSP--PLDSHLGPARPSL 2161
Query: 980 YLPVS----GTPNPAPPLLLCAPPSSSGPTQPGKGSL 1012
P S + PAPP L PS + P GSL
Sbjct: 2162 DFPASAFGFSSLQPAPPQL----PSPAEPRSAPCGSL 2194
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 70.9 bits (172), Expect = 6e-12
Identities = 138/505 (27%), Positives = 162/505 (32%), Gaps = 105/505 (20%)
Query: 548 PPTPSA--------PGTPEP----TEMQSPSTREISDLAFGGS---QQSPEVAAPEPPGS 592
PP PS PG+ P TE Q+ +S AF S P + E S
Sbjct: 811 PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSS-AFKNSCNIPSPPPLPCTESSSS 869
Query: 593 HPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPP 652
P + P + PG P AIP+P ++ T P P G+G+P PP
Sbjct: 870 MPGLGMVPPPPPPL--PGMTVPTLPSTAIPQPPPLQG---TEMLPPPPPPLPGAGIPPPP 924
Query: 653 ADPCGEEGGESKTQEPPALG----PPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARD 708
P G PP G PP P ++ LP P PP P
Sbjct: 925 PLP-----GAGILPLPPLPGAGIPPPPPLPGAAIPPPPPLPGAGIPLPPPLPG------- 972
Query: 709 ASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRL 768
A P A P I P L PG
Sbjct: 973 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL----------------PGA---------- 1006
Query: 769 VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRP----GSPQMQASPSPGIAPKPKTP--- 821
G PL GA P+ AG+ P P G P P GI P P P
Sbjct: 1007 ---GIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAG 1062
Query: 822 --PTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPL 879
P P P A + P PL AG P A PP P P G P
Sbjct: 1063 IPPPPPLPGAGIPPP---PPLPGAGIPPPPPLPGAGIPPP---PPLPGVGIPPPPPLPGA 1116
Query: 880 GKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLAL-GLG 938
G P G P P L P V +PP P P + P L G G
Sbjct: 1117 GIPPPPPLPG----AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAG 1172
Query: 939 LYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAG-----PLDGTYY-------LPVSGT 986
+ PP P+P + +PP P +G P P + AG PL G LP GT
Sbjct: 1173 IPPPP--PLPGVGIPPPPPLPGVGIPPPPPLPGAGIPPPPPLPGMGIPPAPAPPLPPPGT 1230
Query: 987 PNPAPPLLLCAPPSSSGPTQPGKGS 1011
P PPLL P S P P GS
Sbjct: 1231 GIPPPPLL----PVSGPPLLPQVGS 1251
Score = 54.7 bits (130), Expect = 4e-07
Identities = 142/584 (24%), Positives = 181/584 (30%), Gaps = 115/584 (19%)
Query: 407 PRCPSPQNLSPWDRTTRRVSSPLFPEASS-EWENQNPAVEETVSRRSPSPPILSQWNQCV 465
P CP P + +S + P S + ++ P +++S+ P P +L Q
Sbjct: 767 PPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT--QSISQPPPPPSLLWSAGQGQ 824
Query: 466 AGERSP-SLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDP 524
G + P S+ HS + + PSPP P P
Sbjct: 825 PGSQPPHSISTEFQTSHEHSVSSAFKNSCNIPSPP----------------PLPCTESSS 868
Query: 525 MGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEV 584
PG + + PP P PG PT PST G++ P
Sbjct: 869 SMPGLGM--------------VPPPPPPLPGMTVPT---LPSTAIPQPPPLQGTEMLPPP 911
Query: 585 AAPEP----PGSHPVGTLDADKCPEVLGPG-EAASGRPRMAIPRPRDVRKLVKTTYAPG- 638
P P P P+ P + G G P AIP P + PG
Sbjct: 912 PPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPPPPL---------PGA 962
Query: 639 ---FPAGAQGSGLPAPPADPCGEEGGESKTQEPPALG----PPAPAHYTSVFIKDFLPVV 691
P G+G+P PP P G PP G PP P + LP
Sbjct: 963 GIPLPPPLPGAGIPPPPPLP-----GAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA 1017
Query: 692 PHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRV 751
P PP P A P A P LPGA P + +
Sbjct: 1018 GIPPPPPLPG-------AGIPPPPPLPGAGIPPPPP-------LPGAGIPPPPPLPGAGI 1063
Query: 752 RARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRP----GSPQMQ 807
P L G PL GA P+ AG+ P P G P
Sbjct: 1064 PPPPP-----------LPGAGIPPPPPLPGA-GIPPPPPLPGAGIPPPPPLPGVGIPPPP 1111
Query: 808 ASPSPGIAPKPKTP-----PTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRS 862
P GI P P P P P P A + P PL G P A PP
Sbjct: 1112 PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPP---PPLPRVGIPPPPPLPGAGIPPP--- 1165
Query: 863 PQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSS 922
P P G P +G P G V P P L P + +PP+
Sbjct: 1166 PPLPGAGIPPPPPLPGVGIPPPPPLPG----VGIPPPPPLPGAGIPPPPPLPGMGIPPA- 1220
Query: 923 PGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQL 966
P PP + P G G+ PP P+ L P G L +PQ+
Sbjct: 1221 PAPP--LPPP---GTGIPPPPLLPVSGPPLLPQVGSSTLPTPQV 1259
Score = 45.4 bits (106), Expect = 3e-04
Identities = 58/238 (24%), Positives = 86/238 (36%), Gaps = 51/238 (21%)
Query: 785 SSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA---PEPAAAVQAPLPREPLA 841
S Q SP GV + P G+ +P PP A P+ + L P
Sbjct: 743 SIQTSPTEEGGV---------LTLPPVDGLPGRPPCPPGAESGPQTKFCSEISLIVSPRR 793
Query: 842 LAGRTAPAQPRAASAPPTDRSPQSPS---QGARRQPGAAPLGKVLVDPESGRYYFVEAPR 898
++ + QP + + P P PS + QPG+ P + + ++ + V +
Sbjct: 794 ISVQLDSHQPTQSISQP----PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAF 849
Query: 899 QPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGP 958
+ + PS P P + GLG+ PP P+P +++P P
Sbjct: 850 KNSCNI---------------PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLP-- 892
Query: 959 QALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSG------PTQPGKG 1010
+ PQ P PL GT LP P P P + PP G P PG G
Sbjct: 893 -STAIPQPP------PLQGTEMLP--PPPPPLPGAGIPPPPPLPGAGILPLPPLPGAG 941
Score = 43.1 bits (100), Expect = 0.001
Identities = 113/470 (24%), Positives = 156/470 (33%), Gaps = 97/470 (20%)
Query: 440 QNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAP----------SLWEIPHSAVADA 489
+ PA T SP P ++ + G + EAP +L ++P S A+
Sbjct: 230 EEPAAPPTAV--SPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEP 287
Query: 490 VEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPP 549
EP+ PSP EAP P P+ +++ P S+ EA G +E P
Sbjct: 288 REPQQPPSPGGLPVSEAPSLPAAQ--PAAKDS-----PSSTAFPFPEAGPG--EEAAGAP 338
Query: 550 TPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVA--APEPPGSHPVGTLDADKCPEVL 607
A T E E E + G + +PEV AP+ G P E
Sbjct: 339 VRGAGDTDEEGE---EDAFEDAPRGSPGEEWAPEVGEDAPQRLGEEPE--------EEAQ 387
Query: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQE 667
GP A+ PG PA +Q P P PC + +
Sbjct: 388 GPDAPAAAS-------------------LPGSPAPSQRCFKPYPLITPCYIKTTTRQLSS 428
Query: 668 PPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKP 727
P +P P PEPS +R A S A P
Sbjct: 429 PNHSPSQSPNQ------------SPRIKRRPEPSLSRGSRTALA-----------SVAAP 465
Query: 728 FKRTEIRLPGALALG--RRPEVTSRVRARGP--GGENRDVEAQRLVPDGDGRTSPLGGAR 783
K+ R G LA G R + T + AR P GG +E + + D G SP A+
Sbjct: 466 AKKH--RADGGLAAGLSRSADWTEELGARTPRVGGSAHLLE-RGVASDSGGGVSPALAAK 522
Query: 784 SSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLP-----RE 838
+S +P G ++ G ++ S P+ A+ LP RE
Sbjct: 523 ASG--APAAADGFQNVFTGRTLLEKLFSQQENGPPEEAEKFCSRIIAMGLLLPFSDCFRE 580
Query: 839 PLALAGRTAPAQ-------PRAASAPPTDRSPQSPSQGARRQPGAAPLGK 881
P +T A AA + PT S Q RR P P K
Sbjct: 581 PCNQNAQTNAASFDQDQLYTWAAVSQPTHSLDYSEGQFPRRVPSMGPPSK 630
Score = 42.4 bits (98), Expect = 0.002
Identities = 53/191 (27%), Positives = 68/191 (35%), Gaps = 36/191 (18%)
Query: 777 SPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPS------PGIAPKPKTPPTAPEPAAA 830
SP GA R +GP+G PGSP + + S +A +P+ P P P
Sbjct: 240 SPQPGAFLGLDRFLLGPSGGAGEAPGSPDTEQALSALSDLPESLAAEPREPQQPPSPGGL 299
Query: 831 VQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPL-GKVLVDPESG 889
P++ A AQP A +P + P P G + AP+ G D E
Sbjct: 300 --------PVSEAPSLPAAQPAAKDSPSSTAFP-FPEAGPGEEAAGAPVRGAGDTDEEGE 350
Query: 890 RYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGP--I 947
F +APR G E P P R LG A GP
Sbjct: 351 EDAFEDAPR------------GSPGEEWAPEVGEDAPQR------LGEEPEEEAQGPDAP 392
Query: 948 PSLSLPPSPGP 958
+ SLP SP P
Sbjct: 393 AAASLPGSPAP 403
Score = 35.8 bits (81), Expect = 0.21
Identities = 71/261 (27%), Positives = 83/261 (31%), Gaps = 60/261 (22%)
Query: 7 PPALPG--IPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRG 64
PP LPG IP P A G+ G P PP + P A P P PG G
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGIPPPPPLPGA-----GIPPPPPL-PGAGIPPPPP--LPGVG 1106
Query: 65 AGAQPRLSVSAQNSRQRHGPGSGFPRGP-----GSGPRPPQPQLRTLPSGEMEVIFGVGP 119
P L PG+G P P G P PP P P + + G+ P
Sbjct: 1107 IPPPPPL------------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRV-GIPP 1153
Query: 120 LFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPS 179
GA I P PP P A +P +P G L P
Sbjct: 1154 PPPLPGAG-------------IPPPPPLPG--AGIPPPPPLPGVGIPPPPPLPGVGIPPP 1198
Query: 180 PAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTG---- 235
P P GA P +P I P P PP G P P LL +G
Sbjct: 1199 PPLP------------GAGIPPPPPLPGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLL 1246
Query: 236 -SLDESLGPLQAAAGFVQTAL 255
+ S P GF+ L
Sbjct: 1247 PQVGSSTLPTPQVCGFLPPPL 1267
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 69.7 bits (169), Expect = 1e-11
Identities = 203/1012 (20%), Positives = 313/1012 (30%), Gaps = 233/1012 (23%)
Query: 25 QDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQ--RH 82
Q G P +PP P +GP P G P+ S+S+Q +
Sbjct: 197 QKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGT-----PK-SISSQQPEKIKSQ 250
Query: 83 GPGSGFP-RGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFI 141
PG+G P +GP P+ +L PL R+A + T+ A I
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKL---------------PL-------QRDASRPQTKQADI 288
Query: 142 ---SPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAA 198
+ P SP+ P Q P G A P PA P
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTP--GKPPAQQPGHEKSQPGPAKP--------------- 331
Query: 199 PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
PA+P + K + + P + G +P + LGP + A Q + K
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA--------QPLGPAKPPA---QQTGSEK 380
Query: 259 LSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDN-SAPAKAPRPWPS 317
S E P P A G + ++ + + +PL + +PAKAP P +
Sbjct: 381 PSSEQPGPK-ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 318 LRERAIRRDKPAPGTEPL---GPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPP 374
++ P PG P GP +S Q+ T+ P + P PP
Sbjct: 440 PVQQ------PGPGKIPAQQAGPGKTSA--------QQTGPTKPPSQLPGPA-----KPP 480
Query: 375 FECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEAS 434
+ P++ P + +P S PP Q P P+ P P SP P ++
Sbjct: 481 PQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ-----------PGST 527
Query: 435 SEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERS-----PSLEAPSLWEIPHSAVADA 489
Q + + + + SP+ P Q + V+ S P +PS + P +
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Query: 490 VEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQE--AQNGLTQEELA 547
+ P + + E + T + + P + +E N + L
Sbjct: 588 ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 548 PPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVL 607
P +P+P +P T + A S P+ +P+
Sbjct: 648 GDLAPVPSSPQPKLKTAPVT---TTSAVSKSSPQPQQTSPKK------------------ 686
Query: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQE 667
+AA + P P+ LVK G P+ P AD S ++
Sbjct: 687 ---DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA---KAKQPPEAD--------SLSKP 732
Query: 668 PPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEP--SFDTVARDASQPNGVLRRRAENSTA 725
P P P+ + D P P +P S + P+ ++ +AE T
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 726 KPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSS 785
P K + + P +V R +++ P ++
Sbjct: 793 PPLKTDSAKPSQSF-----PPTGEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQ 843
Query: 786 SQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGR 845
Q PV + P Q + SP P P PK PT P P
Sbjct: 844 KQVDPVQ----KKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP------------------ 881
Query: 846 TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVL 905
+P A PT + P + +RR
Sbjct: 882 ----RPTAGQTVPTPQQSPKPQEQSRR--------------------------------- 904
Query: 906 FDPESGQYVEVLLPPSSPGPPHRVYTPLALGLG--LYPPAYGPIPSLSLPPSPGPQALGS 963
F G + P S P P T G G ++ A I S PGP
Sbjct: 905 FSLNLGSITDA--PKSQPTTPQETVTGKLFGFGASIFSQASNLI---STAGQPGPH---- 955
Query: 964 PQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL 1015
S++GP P+ P P+ P PP S+G P P+
Sbjct: 956 ------SQSGP-----GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Score = 63.2 bits (152), Expect = 1e-09
Identities = 179/788 (22%), Positives = 271/788 (34%), Gaps = 173/788 (21%)
Query: 144 LPPGPASPAAV--PRQSQVPDGGSRWATYLELRPRGPSPAAPAQ-----FECVEVALEEG 196
LP G PAA P + + S RP P P PAQ + E
Sbjct: 66 LPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRP--PDPGRPAQPGLSKSRTTDTFRSEQ 123
Query: 197 AAPAR-PRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTAL 255
P R P T+ ++ + R + +++ P G L E + L A + V
Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMP--------GFLSE-VNALSAVSSVVN--- 171
Query: 256 ARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPW 315
K +P F SE ET + VV +K + +P + + P+P
Sbjct: 172 --KFNP---------FDLISDSEASQEETTKKQKVV-QKEQGKPEGIIKPPLQQQPPKPI 219
Query: 316 PSLRERAIRRDKPAPGTEPLGP--VSSSIFLQSEEKIQ-EARKTRFPREAPDRT------ 366
P + PG +PL SI Q EKI+ + T P + P +T
Sbjct: 220 PK---------QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270
Query: 367 ---VQRARSPPFECRIPSEVPSRAVRPRSPSP---PRQTPNGAVRGPRCPSPQNLSPWDR 420
+QR S P + + V +V+P PSP P Q P + P + P
Sbjct: 271 KLPLQRDASRP-QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 421 TTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPI-LSQWNQCVAGERSPSLEAPSLW 479
S L + + P V+ + + P+ P+ ++ G PS E P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-- 387
Query: 480 EIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQN 539
P++ PP G +P + P P + T +
Sbjct: 388 ------------PKALAQPPGV-------------GKTPAQQPGPAKPPTQQVGTPKP-- 420
Query: 540 GLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLD 599
L Q+ APG P T +Q P +I G + S + P P S G
Sbjct: 421 -LAQQPGLQSPAKAPG-PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP-- 476
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAP----PADP 655
A P+ GP + +P A P P+ GS P P PA P
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKP-----------------PSQQPGSTKPPPQQPGPAKP 519
Query: 656 CGEEGGESK--TQEP----PALGPPAPAHYTSVFIKDFLPVVP----HPYEPPEPSFDTV 705
++ G +K +Q+P P+ P+PA ++ + PV P +PP TV
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQPP-----TV 572
Query: 706 ARDASQPNGV------------------LRRRAENSTAKPFKRTEIRLPGALALGRRPEV 747
+ A QP + +A +T + T L G EV
Sbjct: 573 SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 748 TSRV-----RARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG 802
+ R GG+ V + P +T+P+ + S+ SP P+
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSS---PQPKLKTAPVTTTSAVSKSSP-------QPQQT 682
Query: 803 SPQMQASPSPGI--APKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTD 860
SP+ A+P + AP+PK PP + Q L P A A + A + APP +
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVK-----QPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 861 RSPQSPSQ 868
P PS+
Sbjct: 738 --PSVPSE 743
Score = 62.4 bits (150), Expect = 2e-09
Identities = 115/527 (21%), Positives = 179/527 (33%), Gaps = 104/527 (19%)
Query: 517 SPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPE----PTEMQSPSTREISD 572
SP T P G + ++ E + + ++A A G P+ P +SPS +
Sbjct: 31 SPSHTAIPAGMEADLSQLSEEE----RRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQE 86
Query: 573 LAFGG----SQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVR 628
L S + P+ P PG T D + + L PG + S D++
Sbjct: 87 LDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKL-PGRSPSTISLKESKSRTDLK 145
Query: 629 KLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIK--- 685
+ K++ PGF + A + +SV K
Sbjct: 146 EEHKSSMMPGFLSEVN------------------------------ALSAVSSVVNKFNP 175
Query: 686 -DFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRR 744
D + E V ++ +P G+++ + KP + + L
Sbjct: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGT 235
Query: 745 PEVTS-----RVRARGPGGENRDVEAQRLVPDGDGRTSPL----------------GGAR 783
P+ S +++++ PG + ++ P D PL G +
Sbjct: 236 PKSISSQQPEKIKSQPPG-TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 784 SSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALA 843
S SP P ++ P PG P Q P P PP P + + PL ++P +
Sbjct: 295 KPSLPSPSKPP-IQQPTPGKPPAQQPGHEKSQPGPAKPPAQP---SGLTKPLAQQPGTVK 350
Query: 844 GRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLR 903
P QP + PP P P++ +Q G+ P S QP +
Sbjct: 351 ---PPVQPPGTTKPPAQ--PLGPAKPPAQQTGSEK-------PSS---------EQPGPK 389
Query: 904 VLFDPESGQYVEVLLPPSSPGPPHRVYTP--LALGLGLYPPAYGPIPSLSLPPSPGPQAL 961
L P P + P +V TP LA GL PA P P+ + PGP +
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 962 GSPQL-PWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQP 1007
+ Q P + A T P S P PA P PP GP +P
Sbjct: 450 PAQQAGPGKTSAQQTGPTK--PPSQLPGPAKP-----PPQQPGPAKP 489
Score = 58.2 bits (139), Expect = 4e-08
Identities = 153/672 (22%), Positives = 227/672 (33%), Gaps = 152/672 (22%)
Query: 7 PPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAG 66
PP + P Q P G+ PG P A GP P PG G
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK----APGPTKTPVQQPGPGK- 448
Query: 67 AQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGA 126
+ + + S Q+ GP + PG PPQ P + A
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP-----------GSA 497
Query: 127 DDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQF 186
Q T+P P PGPA P+ P+Q S+ + + PSPA P+
Sbjct: 498 KPPSQQPGSTKPP---PQQPGPAKPS--PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 187 ECVEVALEEGAA-PARPRTVPKRQIELRPRPQSPPRAAGAPRP--------RLLLRT--- 234
+ + + G+ P +P TV P + PP + G P+ LLL
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVS-------PSAKQPP-SQGLPKTICPLCNTTELLLHVPEK 604
Query: 235 ---GSLDESLGPLQAAAGF--------------VQTALARKLSPE-APAPSS-------- 268
+ E + + GF + + R L + AP PSS
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664
Query: 269 --ATFGSTGRSEPETRETARSTHVV----LEKA---KSRPLRVRD----NSAPAKAPRPW 315
T + +S P+ ++T+ L KA K P V+ S AKA +P
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP- 723
Query: 316 PSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPF 375
A KPAP EP P +++K ++ + + P + + S
Sbjct: 724 ----PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK-----PTTDLVSSSSATT 774
Query: 376 ECRIPS-EVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEAS 434
+ IPS +V S+A +PP +T + P+ + +SP+D S P +
Sbjct: 775 KPDIPSSKVQSQA--EEKTTPPLKTDSAKPSQSFPPTGEKVSPFD-------SKAIPRPA 825
Query: 435 SEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVE-PR 493
S+ + +S PS Q ++ E P + S DA P+
Sbjct: 826 SD--------SKIISHPGPSSESKGQKQVDPVQKK----EEPKKAQTKMSPKPDAKPMPK 873
Query: 494 SSPSPPAFFPWEAPDRPIGTWGPSPQE---------------------------TWDPMG 526
SP+PP P P P PQE T G
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 527 PGSSIAFTQEAQNGLTQEELAPPTPSAPGTP---EPTEMQSPSTREISDLAFGGSQQSPE 583
G+SI F+Q + T + P + S PG P P Q P+++ G +S
Sbjct: 934 FGASI-FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ--------GPPKSTG 984
Query: 584 VAAPEPPGSHPV 595
A P P S PV
Sbjct: 985 QAPPAPAKSIPV 996
Score = 57.4 bits (137), Expect = 7e-08
Identities = 128/609 (21%), Positives = 202/609 (33%), Gaps = 88/609 (14%)
Query: 4 ALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGR 63
A PP PG + P P + S GS P P P P G P PG
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 64 GAGAQPRLSVSAQNSRQRHGP----GSGFP-RGPGSGPRPPQPQLRTLPS------GEME 112
+ + S + +++Q P GSG P + P P QP + LP E
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTE 596
Query: 113 VIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLE 172
++ V A+ + T + P P ++ + + A +
Sbjct: 597 LLLHVP-----EKANFNTCTECQTTVCSLCGFNPNPHLTEV--KEWLCLNCQMKRALGGD 649
Query: 173 LRPRGPSPAAPAQFECVEVALEEGAAPARPR-------TVPKRQIELRPRPQSPPRAAGA 225
L P SP + V + +P+ PK+ + P P+ PP
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 226 PRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPA-PSSATFGSTGRSEPETRET 284
P L ++ P +A +L++ P+ P+ PS +P+ +
Sbjct: 710 P----TLHGSPSAKAKQPPEA------DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759
Query: 285 ARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFL 344
+ T + V +SA K P ++ +A + P T+ P S F
Sbjct: 760 VKPTTDL----------VSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP--SQSFP 807
Query: 345 QSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEV--------PSRAVRPRSPSPP 396
+ EK+ PR A D + P E + +V P +A SP P
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 397 RQ-------TPNG--AVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEET 447
+ TP G G P+PQ +RR S L + ++Q +ET
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL-GSITDAPKSQPTTPQET 926
Query: 448 VSRR--SPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWE 505
V+ + I SQ + ++ P PHS + +P
Sbjct: 927 VTGKLFGFGASIFSQASNLISTAGQPG---------PHSQSGPGAPMKQAP--------- 968
Query: 506 APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPE-PTEMQS 564
AP +P + GP P P SI +E + E+L P AP TE +
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK-APAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 565 PSTREISDL 573
P ++ L
Sbjct: 1028 PPIKDSKSL 1036
Score = 34.7 bits (78), Expect = 0.47
Identities = 95/450 (21%), Positives = 147/450 (32%), Gaps = 122/450 (27%)
Query: 146 PGPASPAAVPRQSQVPDGG--SRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPR 203
P + +A P QS P G S + + RP S E ++ P + +
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852
Query: 204 TVPKR-QIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPE 262
PK+ Q ++ P+P + P G+P +P
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSP---------------------------------TPP 879
Query: 263 APAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERA 322
P P++ T + P+ +E +R + L + AP+ P+ +
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNL-------------GSITDAPKSQPTTPQET 926
Query: 323 IRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSE 382
+ T L +SIF Q+ I A + P Q P + +
Sbjct: 927 V--------TGKLFGFGASIFSQASNLISTAGQ-------PGPHSQSGPGAPMK-----Q 966
Query: 383 VPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRR-VSSPLFPEASSEWENQN 441
P+ + P S PP+ T G P+P P + T+ + L P+A Q
Sbjct: 967 APAPSQPPTSQGPPKST------GQAPPAPAKSIPVKKETKAPAAEKLEPKA-----EQA 1015
Query: 442 PAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAF 501
P V+ T + + P PPI ++ SL P AV + SP P +
Sbjct: 1016 PTVKRTETEKKP-PPI---------------KDSKSLTAEPQKAVL-PTKLEKSPKPEST 1058
Query: 502 FPWEAPDRPIGTWGPSPQETWDP----------MGPGSSIAFTQE--AQNGLTQEELA-- 547
P + IG+ P T P + QE N TQ ++
Sbjct: 1059 CPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118
Query: 548 -------PPTPSAPGT---PEPTEMQSPST 567
PP PS P P PTE S T
Sbjct: 1119 LGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
Score = 33.1 bits (74), Expect = 1.4
Identities = 48/236 (20%), Positives = 86/236 (36%), Gaps = 14/236 (5%)
Query: 338 VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPR 397
+S++ F E QE ++ P +P + A+ PF ++ ++ P P PP
Sbjct: 2356 LSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
Query: 398 QTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPI 457
P P P P + P ++++ ++ + +E T RS P+
Sbjct: 2416 PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPV 2475
Query: 458 LSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEA-PDRPIGTWGP 516
C +P P IP V R PS P P P P T P
Sbjct: 2476 T---RICTT---APPPVPPKPSSIPSGLV---FTHRPEPSKPPIAPKPVIPQLPTTTQKP 2526
Query: 517 SPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISD 572
+ P G S+ + N +T + P+P++P +P + ++ +++
Sbjct: 2527 TDIH---PKPTGLSLT-SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTE 2578
Score = 32.3 bits (72), Expect = 2.3
Identities = 23/83 (27%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Query: 769 VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPA 828
+P G S L RS + P P P P P P P PP P P
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP----PPPPPPPPPPPPPPLPPPT 2431
Query: 829 AAVQAPLPREPLALAGRTAPAQP 851
+ LP++ L +A A P
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATP 2454
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 69.7 bits (169), Expect = 1e-11
Identities = 203/1012 (20%), Positives = 313/1012 (30%), Gaps = 233/1012 (23%)
Query: 25 QDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQ--RH 82
Q G P +PP P +GP P G P+ S+S+Q +
Sbjct: 197 QKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGT-----PK-SISSQQPEKIKSQ 250
Query: 83 GPGSGFP-RGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFI 141
PG+G P +GP P+ +L PL R+A + T+ A I
Sbjct: 251 PPGTGKPIQGPTQTPQTDHAKL---------------PL-------QRDASRPQTKQADI 288
Query: 142 ---SPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAA 198
+ P SP+ P Q P G A P PA P
Sbjct: 289 VRGESVKPSLPSPSKPPIQQPTP--GKPPAQQPGHEKSQPGPAKP--------------- 331
Query: 199 PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
PA+P + K + + P + G +P + LGP + A Q + K
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPA--------QPLGPAKPPA---QQTGSEK 380
Query: 259 LSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDN-SAPAKAPRPWPS 317
S E P P A G + ++ + + +PL + +PAKAP P +
Sbjct: 381 PSSEQPGPK-ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKT 439
Query: 318 LRERAIRRDKPAPGTEPL---GPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPP 374
++ P PG P GP +S Q+ T+ P + P PP
Sbjct: 440 PVQQ------PGPGKIPAQQAGPGKTSA--------QQTGPTKPPSQLPGPA-----KPP 480
Query: 375 FECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEAS 434
+ P++ P + +P S PP Q P P+ P P SP P ++
Sbjct: 481 PQQPGPAKPPPQ--QPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQ-----------PGST 527
Query: 435 SEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERS-----PSLEAPSLWEIPHSAVADA 489
Q + + + + SP+ P Q + V+ S P +PS + P +
Sbjct: 528 KPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKT 587
Query: 490 VEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQE--AQNGLTQEELA 547
+ P + + E + T + + P + +E N + L
Sbjct: 588 ICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALG 647
Query: 548 PPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVL 607
P +P+P +P T + A S P+ +P+
Sbjct: 648 GDLAPVPSSPQPKLKTAPVT---TTSAVSKSSPQPQQTSPKK------------------ 686
Query: 608 GPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQE 667
+AA + P P+ LVK G P+ P AD S ++
Sbjct: 687 ---DAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSA---KAKQPPEAD--------SLSKP 732
Query: 668 PPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEP--SFDTVARDASQPNGVLRRRAENSTA 725
P P P+ + D P P +P S + P+ ++ +AE T
Sbjct: 733 APPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTT 792
Query: 726 KPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSS 785
P K + + P +V R +++ P ++
Sbjct: 793 PPLKTDSAKPSQSF-----PPTGEKVSPFDSKAIPRPASDSKII----SHPGPSSESKGQ 843
Query: 786 SQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGR 845
Q PV + P Q + SP P P PK PT P P
Sbjct: 844 KQVDPVQ----KKEEPKKAQTKMSPKPDAKPMPKGSPTPPGP------------------ 881
Query: 846 TAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVL 905
+P A PT + P + +RR
Sbjct: 882 ----RPTAGQTVPTPQQSPKPQEQSRR--------------------------------- 904
Query: 906 FDPESGQYVEVLLPPSSPGPPHRVYTPLALGLG--LYPPAYGPIPSLSLPPSPGPQALGS 963
F G + P S P P T G G ++ A I S PGP
Sbjct: 905 FSLNLGSITDA--PKSQPTTPQETVTGKLFGFGASIFSQASNLI---STAGQPGPH---- 955
Query: 964 PQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFPL 1015
S++GP P+ P P+ P PP S+G P P+
Sbjct: 956 ------SQSGP-----GAPMKQAPAPSQPPTSQGPPKSTGQAPPAPAKSIPV 996
Score = 63.2 bits (152), Expect = 1e-09
Identities = 179/788 (22%), Positives = 271/788 (34%), Gaps = 173/788 (21%)
Query: 144 LPPGPASPAAV--PRQSQVPDGGSRWATYLELRPRGPSPAAPAQ-----FECVEVALEEG 196
LP G PAA P + + S RP P P PAQ + E
Sbjct: 66 LPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRP--PDPGRPAQPGLSKSRTTDTFRSEQ 123
Query: 197 AAPAR-PRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTAL 255
P R P T+ ++ + R + +++ P G L E + L A + V
Sbjct: 124 KLPGRSPSTISLKESKSRTDLKEEHKSSMMP--------GFLSE-VNALSAVSSVVN--- 171
Query: 256 ARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPW 315
K +P F SE ET + VV +K + +P + + P+P
Sbjct: 172 --KFNP---------FDLISDSEASQEETTKKQKVV-QKEQGKPEGIIKPPLQQQPPKPI 219
Query: 316 PSLRERAIRRDKPAPGTEPLGP--VSSSIFLQSEEKIQ-EARKTRFPREAPDRT------ 366
P + PG +PL SI Q EKI+ + T P + P +T
Sbjct: 220 PK---------QQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHA 270
Query: 367 ---VQRARSPPFECRIPSEVPSRAVRPRSPSP---PRQTPNGAVRGPRCPSPQNLSPWDR 420
+QR S P + + V +V+P PSP P Q P + P + P
Sbjct: 271 KLPLQRDASRP-QTKQADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA 329
Query: 421 TTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPI-LSQWNQCVAGERSPSLEAPSLW 479
S L + + P V+ + + P+ P+ ++ G PS E P
Sbjct: 330 KPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-- 387
Query: 480 EIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQN 539
P++ PP G +P + P P + T +
Sbjct: 388 ------------PKALAQPPGV-------------GKTPAQQPGPAKPPTQQVGTPKP-- 420
Query: 540 GLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLD 599
L Q+ APG P T +Q P +I G + S + P P S G
Sbjct: 421 -LAQQPGLQSPAKAPG-PTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP-- 476
Query: 600 ADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAP----PADP 655
A P+ GP + +P A P P+ GS P P PA P
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKP-----------------PSQQPGSTKPPPQQPGPAKP 519
Query: 656 CGEEGGESK--TQEP----PALGPPAPAHYTSVFIKDFLPVVP----HPYEPPEPSFDTV 705
++ G +K +Q+P P+ P+PA ++ + PV P +PP TV
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ--QSTKPVSQTGSGKPLQPP-----TV 572
Query: 706 ARDASQPNGV------------------LRRRAENSTAKPFKRTEIRLPGALALGRRPEV 747
+ A QP + +A +T + T L G EV
Sbjct: 573 SPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEV 632
Query: 748 TSRV-----RARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG 802
+ R GG+ V + P +T+P+ + S+ SP P+
Sbjct: 633 KEWLCLNCQMKRALGGDLAPVPSS---PQPKLKTAPVTTTSAVSKSSP-------QPQQT 682
Query: 803 SPQMQASPSPGI--APKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTD 860
SP+ A+P + AP+PK PP + Q L P A A + A + APP +
Sbjct: 683 SPKKDAAPKQDLSKAPEPKKPPPLVK-----QPTLHGSPSAKAKQPPEADSLSKPAPPKE 737
Query: 861 RSPQSPSQ 868
P PS+
Sbjct: 738 --PSVPSE 743
Score = 62.4 bits (150), Expect = 2e-09
Identities = 115/527 (21%), Positives = 179/527 (33%), Gaps = 104/527 (19%)
Query: 517 SPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPE----PTEMQSPSTREISD 572
SP T P G + ++ E + + ++A A G P+ P +SPS +
Sbjct: 31 SPSHTAIPAGMEADLSQLSEEE----RRQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQE 86
Query: 573 LAFGG----SQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVR 628
L S + P+ P PG T D + + L PG + S D++
Sbjct: 87 LDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKL-PGRSPSTISLKESKSRTDLK 145
Query: 629 KLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIK--- 685
+ K++ PGF + A + +SV K
Sbjct: 146 EEHKSSMMPGFLSEVN------------------------------ALSAVSSVVNKFNP 175
Query: 686 -DFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRR 744
D + E V ++ +P G+++ + KP + + L
Sbjct: 176 FDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGT 235
Query: 745 PEVTS-----RVRARGPGGENRDVEAQRLVPDGDGRTSPL----------------GGAR 783
P+ S +++++ PG + ++ P D PL G +
Sbjct: 236 PKSISSQQPEKIKSQPPG-TGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESV 294
Query: 784 SSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALA 843
S SP P ++ P PG P Q P P PP P + + PL ++P +
Sbjct: 295 KPSLPSPSKPP-IQQPTPGKPPAQQPGHEKSQPGPAKPPAQP---SGLTKPLAQQPGTVK 350
Query: 844 GRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLR 903
P QP + PP P P++ +Q G+ P S QP +
Sbjct: 351 ---PPVQPPGTTKPPAQ--PLGPAKPPAQQTGSEK-------PSS---------EQPGPK 389
Query: 904 VLFDPESGQYVEVLLPPSSPGPPHRVYTP--LALGLGLYPPAYGPIPSLSLPPSPGPQAL 961
L P P + P +V TP LA GL PA P P+ + PGP +
Sbjct: 390 ALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKI 449
Query: 962 GSPQL-PWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQP 1007
+ Q P + A T P S P PA P PP GP +P
Sbjct: 450 PAQQAGPGKTSAQQTGPTK--PPSQLPGPAKP-----PPQQPGPAKP 489
Score = 58.2 bits (139), Expect = 4e-08
Identities = 153/672 (22%), Positives = 227/672 (33%), Gaps = 152/672 (22%)
Query: 7 PPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAG 66
PP + P Q P G+ PG P A GP P PG G
Sbjct: 394 PPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK----APGPTKTPVQQPGPGK- 448
Query: 67 AQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGA 126
+ + + S Q+ GP + PG PPQ P + A
Sbjct: 449 IPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQP-----------GSA 497
Query: 127 DDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQF 186
Q T+P P PGPA P+ P+Q S+ + + PSPA P+
Sbjct: 498 KPPSQQPGSTKPP---PQQPGPAKPS--PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQ 552
Query: 187 ECVEVALEEGAA-PARPRTVPKRQIELRPRPQSPPRAAGAPRP--------RLLLRT--- 234
+ + + G+ P +P TV P + PP + G P+ LLL
Sbjct: 553 QSTKPVSQTGSGKPLQPPTVS-------PSAKQPP-SQGLPKTICPLCNTTELLLHVPEK 604
Query: 235 ---GSLDESLGPLQAAAGF--------------VQTALARKLSPE-APAPSS-------- 268
+ E + + GF + + R L + AP PSS
Sbjct: 605 ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTA 664
Query: 269 --ATFGSTGRSEPETRETARSTHVV----LEKA---KSRPLRVRD----NSAPAKAPRPW 315
T + +S P+ ++T+ L KA K P V+ S AKA +P
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQP- 723
Query: 316 PSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPF 375
A KPAP EP P +++K ++ + + P + + S
Sbjct: 724 ----PEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVK-----PTTDLVSSSSATT 774
Query: 376 ECRIPS-EVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEAS 434
+ IPS +V S+A +PP +T + P+ + +SP+D S P +
Sbjct: 775 KPDIPSSKVQSQA--EEKTTPPLKTDSAKPSQSFPPTGEKVSPFD-------SKAIPRPA 825
Query: 435 SEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVE-PR 493
S+ + +S PS Q ++ E P + S DA P+
Sbjct: 826 SD--------SKIISHPGPSSESKGQKQVDPVQKK----EEPKKAQTKMSPKPDAKPMPK 873
Query: 494 SSPSPPAFFPWEAPDRPIGTWGPSPQE---------------------------TWDPMG 526
SP+PP P P P PQE T G
Sbjct: 874 GSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFG 933
Query: 527 PGSSIAFTQEAQNGLTQEELAPPTPSAPGTP---EPTEMQSPSTREISDLAFGGSQQSPE 583
G+SI F+Q + T + P + S PG P P Q P+++ G +S
Sbjct: 934 FGASI-FSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQ--------GPPKSTG 984
Query: 584 VAAPEPPGSHPV 595
A P P S PV
Sbjct: 985 QAPPAPAKSIPV 996
Score = 57.4 bits (137), Expect = 7e-08
Identities = 128/609 (21%), Positives = 202/609 (33%), Gaps = 88/609 (14%)
Query: 4 ALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGR 63
A PP PG + P P + S GS P P P P G P PG
Sbjct: 477 AKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPGS 536
Query: 64 GAGAQPRLSVSAQNSRQRHGP----GSGFP-RGPGSGPRPPQPQLRTLPS------GEME 112
+ + S + +++Q P GSG P + P P QP + LP E
Sbjct: 537 AKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTE 596
Query: 113 VIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLE 172
++ V A+ + T + P P ++ + + A +
Sbjct: 597 LLLHVP-----EKANFNTCTECQTTVCSLCGFNPNPHLTEV--KEWLCLNCQMKRALGGD 649
Query: 173 LRPRGPSPAAPAQFECVEVALEEGAAPARPR-------TVPKRQIELRPRPQSPPRAAGA 225
L P SP + V + +P+ PK+ + P P+ PP
Sbjct: 650 LAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQ 709
Query: 226 PRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPA-PSSATFGSTGRSEPETRET 284
P L ++ P +A +L++ P+ P+ PS +P+ +
Sbjct: 710 P----TLHGSPSAKAKQPPEA------DSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKM 759
Query: 285 ARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFL 344
+ T + V +SA K P ++ +A + P T+ P S F
Sbjct: 760 VKPTTDL----------VSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKP--SQSFP 807
Query: 345 QSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEV--------PSRAVRPRSPSPP 396
+ EK+ PR A D + P E + +V P +A SP P
Sbjct: 808 PTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867
Query: 397 RQ-------TPNG--AVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEET 447
+ TP G G P+PQ +RR S L + ++Q +ET
Sbjct: 868 AKPMPKGSPTPPGPRPTAGQTVPTPQQSPKPQEQSRRFSLNL-GSITDAPKSQPTTPQET 926
Query: 448 VSRR--SPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWE 505
V+ + I SQ + ++ P PHS + +P
Sbjct: 927 VTGKLFGFGASIFSQASNLISTAGQPG---------PHSQSGPGAPMKQAP--------- 968
Query: 506 APDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPE-PTEMQS 564
AP +P + GP P P SI +E + E+L P AP TE +
Sbjct: 969 APSQPPTSQGPPKSTGQAPPAPAKSIPVKKETK-APAAEKLEPKAEQAPTVKRTETEKKP 1027
Query: 565 PSTREISDL 573
P ++ L
Sbjct: 1028 PPIKDSKSL 1036
Score = 34.7 bits (78), Expect = 0.47
Identities = 95/450 (21%), Positives = 147/450 (32%), Gaps = 122/450 (27%)
Query: 146 PGPASPAAVPRQSQVPDGG--SRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPR 203
P + +A P QS P G S + + RP S E ++ P + +
Sbjct: 793 PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKK 852
Query: 204 TVPKR-QIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPE 262
PK+ Q ++ P+P + P G+P +P
Sbjct: 853 EEPKKAQTKMSPKPDAKPMPKGSP---------------------------------TPP 879
Query: 263 APAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERA 322
P P++ T + P+ +E +R + L + AP+ P+ +
Sbjct: 880 GPRPTAGQTVPTPQQSPKPQEQSRRFSLNL-------------GSITDAPKSQPTTPQET 926
Query: 323 IRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSE 382
+ T L +SIF Q+ I A + P Q P + +
Sbjct: 927 V--------TGKLFGFGASIFSQASNLISTAGQ-------PGPHSQSGPGAPMK-----Q 966
Query: 383 VPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRR-VSSPLFPEASSEWENQN 441
P+ + P S PP+ T G P+P P + T+ + L P+A Q
Sbjct: 967 APAPSQPPTSQGPPKST------GQAPPAPAKSIPVKKETKAPAAEKLEPKA-----EQA 1015
Query: 442 PAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAF 501
P V+ T + + P PPI ++ SL P AV + SP P +
Sbjct: 1016 PTVKRTETEKKP-PPI---------------KDSKSLTAEPQKAVL-PTKLEKSPKPEST 1058
Query: 502 FPWEAPDRPIGTWGPSPQETWDP----------MGPGSSIAFTQE--AQNGLTQEELA-- 547
P + IG+ P T P + QE N TQ ++
Sbjct: 1059 CPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQEWLCLNCQTQRAISGQ 1118
Query: 548 -------PPTPSAPGT---PEPTEMQSPST 567
PP PS P P PTE S T
Sbjct: 1119 LGDIRKMPPAPSGPKASPMPVPTESSSQKT 1148
Score = 33.1 bits (74), Expect = 1.4
Identities = 48/236 (20%), Positives = 86/236 (36%), Gaps = 14/236 (5%)
Query: 338 VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPR 397
+S++ F E QE ++ P +P + A+ PF ++ ++ P P PP
Sbjct: 2356 LSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPP 2415
Query: 398 QTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPI 457
P P P P + P ++++ ++ + +E T RS P+
Sbjct: 2416 PPPPPPPPPPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPV 2475
Query: 458 LSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEA-PDRPIGTWGP 516
C +P P IP V R PS P P P P T P
Sbjct: 2476 T---RICTT---APPPVPPKPSSIPSGLV---FTHRPEPSKPPIAPKPVIPQLPTTTQKP 2526
Query: 517 SPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREISD 572
+ P G S+ + N +T + P+P++P +P + ++ +++
Sbjct: 2527 TDIH---PKPTGLSLT-SSMTLNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTE 2578
Score = 32.3 bits (72), Expect = 2.3
Identities = 23/83 (27%), Positives = 29/83 (34%), Gaps = 4/83 (4%)
Query: 769 VPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPA 828
+P G S L RS + P P P P P P P PP P P
Sbjct: 2376 LPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPP----PPPPPPPPPPPPPPLPPPT 2431
Query: 829 AAVQAPLPREPLALAGRTAPAQP 851
+ LP++ L +A A P
Sbjct: 2432 SPKPTILPKKKLTVASPVTTATP 2454
>gi|132626688 mediator of DNA-damage checkpoint 1 [Homo sapiens]
Length = 2089
Score = 68.9 bits (167), Expect = 2e-11
Identities = 221/1011 (21%), Positives = 325/1011 (32%), Gaps = 224/1011 (22%)
Query: 42 EPPDVGPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQP 101
EP D KG A+ P PG GAG P GP S P
Sbjct: 950 EPEGGSQDQKGQASSPTPEPGVGAGDLP---------------------GPTSAP----- 983
Query: 102 QLRTLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVP 161
+PSG SG + + ++ P PA A+ R ++
Sbjct: 984 ----VPSGSQ------------SGGRGSPVSPRRHQKGLLNCKMP-PAEKASRIRAAEKV 1026
Query: 162 DGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRP-QSPP 220
G + SP A C+ + E AP + + Q L P P SP
Sbjct: 1027 SRGDQ-----------ESPDA-----CLPPTVPEAPAPPQKPLNSQSQKHLAPPPLLSPL 1070
Query: 221 RAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGST------ 274
+ P R + GS + PL + +L P P P T S+
Sbjct: 1071 LPSIKPTVRKTRQDGSQEAPEAPLSS-----------ELEPFHPKPKIRTRKSSRMTPFP 1119
Query: 275 -GRSEPETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTE 333
+ PE + + V K S+ R R N + K P P AP +
Sbjct: 1120 ATSAAPEPHPSTSTAQPVTPKPTSQATRSRTNRSSVKTPEPVV----------PTAPELQ 1169
Query: 334 PLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRA----RSPPFECRIPSEVPSRAVR 389
P + + ++ RK+R + P+ V A S + + SE S+A R
Sbjct: 1170 PSTSTDQPVTSEPTSQVTRGRKSRSSVKTPETVVPTALELQPSTSTDRPVTSEPTSQATR 1229
Query: 390 PRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVS 449
R +TP P P+ L P T + V+S +A+ +N++ S
Sbjct: 1230 GRKNRSSVKTPE-----PVVPTAPELQPSTSTDQPVTSEPTYQATRGRKNRS-------S 1277
Query: 450 RRSPSPPILSQWNQCVAGERSPSLEAP-SLWEIPHSAVADAVEPRSSPSPPAFFPWEAPD 508
++P P + + A E PS + P S + SS P AP+
Sbjct: 1278 VKTPEPVVPT------APELRPSTSTDRPVTPKPTSRTTRSRTNMSSVKTPETVVPTAPE 1331
Query: 509 RPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTR 568
I T T P+ P + T+ N + + P AP P T + P T
Sbjct: 1332 LQIST------STDQPVTPKPTSRTTRSRTNMSSVKNPESTVPIAPELPPSTSTEQPVTP 1385
Query: 569 EISDLAFGG-----SQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPR 623
E + A G S ++PE P P P + D PE P R
Sbjct: 1386 EPTSRATRGRKNRSSGKTPETLVPTAPKLEPSTSTDQPVTPE-----------PTSQATR 1434
Query: 624 PRDVRKLVKT--TYAPGFP-----AGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAP 676
R R VKT T P P P P + S + P + P AP
Sbjct: 1435 GRTNRSSVKTPETVVPTAPELQPSTSTDQPVTPEPTSQATRGRTDRSSVKTPETVVPTAP 1494
Query: 677 AHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLP 736
+ S T S+P R +N ++ K E +P
Sbjct: 1495 --------------------ELQASASTDQPVTSEPTSRTTRGRKNRSS--VKTPETVVP 1532
Query: 737 GALALGR--------RPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQR 788
A L PE TSR RG + + +VP P S+S+
Sbjct: 1533 AAPELQPSTSTDQPVTPEPTSRA-TRGRTNRSSVKTPESIVPIAP-ELQP-----STSRN 1585
Query: 789 SPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRT-- 846
V P P + + + + S P+P PTAPEP P P + T
Sbjct: 1586 QLVTP----EPTSRATRCRTNRSSVKTPEP-VVPTAPEPHPTTSTDQPVTPKLTSRATRR 1640
Query: 847 ----------APAQPRAASA---PPTDRS--PQSPSQGARRQPGAAPLGKVLVDPESGRY 891
P +P A+ PTD+S P++ +QG + + + + + P + +
Sbjct: 1641 KTNRSSVKTPKPVEPAASDLEPFTPTDQSVTPEAIAQGGQSKTLRSSTVRAMPVPTTPEF 1700
Query: 892 YFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLS 951
QP PE + + G P + P+ + P S
Sbjct: 1701 QSPVTTDQP-----ISPEPITQPSCIKRQRAAGNPGSLAAPID-----HKPC-------S 1743
Query: 952 LPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSS 1002
P P QA + + V A L + P PA P LL P +S
Sbjct: 1744 APLEPKSQASRNQRWGAVRAAESL--------TAIPEPASPQLLETPIHAS 1786
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 68.6 bits (166), Expect = 3e-11
Identities = 174/759 (22%), Positives = 251/759 (33%), Gaps = 167/759 (22%)
Query: 142 SPLPPG-----PASPAAVPRQSQVPDGGSRWATYL-ELRPRGPSPAAPAQFECVEVA--L 193
+PLPP +P P + + +G R L EL R +P AP C
Sbjct: 159 TPLPPPRLADVAPTPPKTPARKRGEEGTERMVQALTELLRRAQAPQAPRSRACEPSTPRR 218
Query: 194 EEGAAPARPRTVPKRQIELR---------PRPQSPPRAAGAPRPRLLLRTGSLDESLGPL 244
G P RP +R+ + P+P+ PP P + +TGS GP
Sbjct: 219 SRGRPPGRPAGPCRRKQQAVVVAEAAVTIPKPEPPP-----PVVPVKHQTGSWKCKEGP- 272
Query: 245 QAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLE--------KAK 296
P P S G R V++ K
Sbjct: 273 ---------------GPGPGTPRRGGQSSRGGRGGRGRGRGGGLPFVIKFVSRAKKVKMG 317
Query: 297 SRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKT 356
L + + W + +R + + G+ + + EEK +E K
Sbjct: 318 QLSLGLESGQGQGQHEESWQDVPQRRVGSGQG--GSPCWKKQEQKLDDEEEEKKEEEEKD 375
Query: 357 RFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSP--PRQTPNGAVRGPRCPSPQN 414
+ E +R V P E + +++P + P +PSP P P+ + P CP P
Sbjct: 376 KEGEEKEERAVAEEMMPAAE-KEEAKLPPPPLTPPAPSPPPPLPPPSTSPPPPLCPPP-- 432
Query: 415 LSPWDRTTRRVSSPLFPEASSEW-ENQNPAVEETVSRRSPSPPIL-SQWNQCVAGERSPS 472
P + + SP P A E E+ P V T SR+ PP+ SQ + A P
Sbjct: 433 --PPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPE 490
Query: 473 LEAPSLWEIPHSAVADAVEPRSSPS-----------------------------PPAFFP 503
+P P + A P SP+ P F
Sbjct: 491 GTSP---PTPTPSTATGGPPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFM 547
Query: 504 WEAPDR------------PIGTWGPSPQETWD-------PMGPGSSIAFTQEAQNGLTQ- 543
E P + PI T P PQE P P + + ++ ++ L +
Sbjct: 548 DEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREP 607
Query: 544 --------EELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVA---------- 585
EL PP P+ P P P+ +P+T L Q +P A
Sbjct: 608 TFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRPLLLRAPQFTPSEAHLKIYESVLT 667
Query: 586 -----APEPPGSHPVGTLDADKCPEVLGPGEAAS-GRPRMAIPRPRDVRKLVKTTYAPGF 639
APE P P D+ PE G PR A V+ V AP
Sbjct: 668 PPPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPAL 727
Query: 640 PAGAQGSGLPAPPADPCGEEGGESKTQ-EPPALGPPAPAHYTSVFIKDFLPVVPHPYEPP 698
G Q P +TQ P AL PP P L P P + P
Sbjct: 728 SNGPQTQAQLLQPLQAL-------QTQLLPQALPPPQPQ----------LQPPPSPQQMP 770
Query: 699 EPSFDTVARDASQP-NGV------LRRRAENSTAKPFKRTEIRLPGALAL---GRRPEVT 748
+A S P +GV L +RA+ K ++ + ++ ++ L G+ EV
Sbjct: 771 PLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVA 830
Query: 749 SRVRA---RGP-GGENRDVEAQRLVPDGDGRTSPLGGAR 783
V+ RGP E+ VEA+R P G SP+ G R
Sbjct: 831 GAVKQISDRGPVRSEDESVEAKRERPSGP--ESPVQGPR 867
Score = 55.8 bits (133), Expect = 2e-07
Identities = 95/381 (24%), Positives = 125/381 (32%), Gaps = 87/381 (22%)
Query: 649 PAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARD 708
P PP P T PP L PP P PV P P P P ++
Sbjct: 413 PPPPLPP-------PSTSPPPPLCPPPPP-----------PVSPPPLPSPPPPPAQEEQE 454
Query: 709 ASQPNGV---LRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEA 765
S P V R+ P +R E A G P + A G E+ A
Sbjct: 455 ESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPTPTPSTATGGPPEDSPTVA 514
Query: 766 -----------QRLVPDGDGRTSP-LGGARSSSQRSPVGPAGV------RSPRPGSPQMQ 807
Q ++P R+S + R P P V R P SP +
Sbjct: 515 PKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPPVP 574
Query: 808 ASPSPGIAP-KPKTPPTAPEPAAAVQAPLPREPL---ALAGRTAPAQPRAASAPPTDRSP 863
P+P +P + TPP+ P P + + REP R P P A PP P
Sbjct: 575 QEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPP 634
Query: 864 QSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSP 923
+P+ +RR PL +L P+ P + L++ Y VL PP
Sbjct: 635 PAPATSSRR-----PL--LLRAPQF-------TPSEAHLKI--------YESVLTPPPLG 672
Query: 924 GPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPV 983
P P P P+ P P P+A+G L + PV
Sbjct: 673 APE--------------APEPEPPPADDSPAEPEPRAVG--------RTNHLSLPRFAPV 710
Query: 984 SGTPNPAPPLLLCAPPSSSGP 1004
TP A AP S+GP
Sbjct: 711 VTTPVKAEVSPHGAPALSNGP 731
Score = 55.5 bits (132), Expect = 3e-07
Identities = 136/551 (24%), Positives = 180/551 (32%), Gaps = 81/551 (14%)
Query: 504 WEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQ 563
W D W + P GP A + A+ T P+ PG +P
Sbjct: 1765 WSTVDARRRCWYRCRILEYRPWGPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDP---- 1820
Query: 564 SPSTREISDLAFGGSQQSPEVAAPEPP-----GSHPVGTLDADKCPEVLGPGEAASGRPR 618
P ++ L G ++ + +PP GS P + + P + S RP
Sbjct: 1821 -PLDTDV--LVPGAPERHSPIQNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPL 1877
Query: 619 MAI-----PRPRDVRKL---VKTTYAPGFPAGAQGSGLPAPPAD-PCGEEGGESKTQEPP 669
+ P P L + T P FPA + S P+P A P + P
Sbjct: 1878 GGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSP 1937
Query: 670 ALGPPAPAHYTSVFIK---DFLPVVPHPYEPPE----PSFDTVARDASQPNGVLRRRAEN 722
L P P + + P P P PP P F+ + + L A
Sbjct: 1938 QLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASL 1997
Query: 723 STAKPFKRTEIRLPGALAL-----GRRPEVTSRVRARGPGGENRDVEAQRLVPD---GDG 774
+PF+ EI GA+ G E S +R V A L P G
Sbjct: 1998 LGTEPFQE-EIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAP 2056
Query: 775 RTSPLGG---ARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAV 831
R L G S + P G +P P P + + G A PP P+ V
Sbjct: 2057 RIEQLDGVDDGTDSEAEAVQQPRGQGTP-PSGPGVVRAGVLGAAGDRARPP-EDLPSEIV 2114
Query: 832 QAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRY 891
L G P + APP Q PSQG P DP
Sbjct: 2115 DFVLKNLGGPGDGGAGPREESLPPAPPLANGSQ-PSQGLTASP---------ADPTR--- 2161
Query: 892 YFVEAPRQPRLRVLFDPESGQYVEVLLPPSSP----GPPHRVYTPLALGLGLYPPAYGPI 947
F P P +RVL G E P +S +V+ +A G P P+
Sbjct: 2162 TFAWLPGAPGVRVL---SLGPAPEPPKPATSKIILVNKLGQVFVKMA---GEGEPVPPPV 2215
Query: 948 PSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPS------S 1001
LPP+ P A S W GPL G LPV G PAPP PP S
Sbjct: 2216 KQPPLPPTISPTAPTS----WTLPPGPLLGV--LPVVGVVRPAPP----PPPPPLTLVLS 2265
Query: 1002 SGPTQPGKGSL 1012
SGP P + ++
Sbjct: 2266 SGPASPPRQAI 2276
Score = 53.1 bits (126), Expect = 1e-06
Identities = 138/585 (23%), Positives = 202/585 (34%), Gaps = 91/585 (15%)
Query: 308 PAKAPRPWPSLRERAIRRDKPAPGTEPLG----PVSSSIFLQSEEKIQEARKTRFPREAP 363
P + P + E PAP +EP G P+ + + + + + P P
Sbjct: 1788 PREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPERHSPIQNLDPPLRP 1847
Query: 364 DRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTR 423
D +PP P ++ + SP R+ P G V PSP + S
Sbjct: 1848 DS----GSAPP---PAPRSFSGARIKVPNYSPSRR-PLGGVSFGPLPSPGSPSSLTHHIP 1899
Query: 424 RVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPH 483
V P FP +P R SPP+ + SP L P P
Sbjct: 1900 TVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPL----------KTSPQLRVP-----PP 1944
Query: 484 SAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQ 543
++V A+ P S P P AP P P E +GP E +GL+
Sbjct: 1945 TSVVTALTPTSGELAP---PGPAP-------SPPPPE---DLGPDFE---DMEVVSGLSA 1988
Query: 544 EELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSH-PVGTLDADK 602
+L S GT EP + + + + G S E ++P H PV + A
Sbjct: 1989 ADL-DFAASLLGT-EPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYIHFPVTVVSA-- 2044
Query: 603 CPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADP----CGE 658
PG A S P PR + + T + A Q G PP+ P G
Sbjct: 2045 ------PGLAPSATP--GAPRIEQLDGVDDGTDSEA-EAVQQPRGQGTPPSGPGVVRAGV 2095
Query: 659 EGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTV--ARDASQPNGVL 716
G PP P+ +K+ P E S + SQP+ L
Sbjct: 2096 LGAAGDRARPP---EDLPSEIVDFVLKNLGGPGDGGAGPREESLPPAPPLANGSQPSQGL 2152
Query: 717 RRRAENSTAKPFKRTEIRLPGA-----LALGRRPE----VTSRVRARGPGGENRDVEAQR 767
+ T RT LPGA L+LG PE TS++ G+ +
Sbjct: 2153 TASPADPT-----RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQ----VFVK 2203
Query: 768 LVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGI---APKPKTPPTA 824
+ +G+ P+ SP P P PG P + P G+ AP P PP
Sbjct: 2204 MAGEGEPVPPPVKQPPLPPTISPTAPTSWTLP-PG-PLLGVLPVVGVVRPAPPPPPPPLT 2261
Query: 825 PEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQG 869
++ +P PR+ + + R + R+ APP ++P+ G
Sbjct: 2262 LVLSSGPASP-PRQAIRVK-RVSTFSGRSPPAPPPYKAPRLDEDG 2304
Score = 52.4 bits (124), Expect = 2e-06
Identities = 154/683 (22%), Positives = 230/683 (33%), Gaps = 116/683 (16%)
Query: 242 GPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSR--- 298
GP + A ++ A + +PAPSS P + T V++ A R
Sbjct: 1787 GPREEPA-HLEAAEENQTIVHSPAPSS--------EPPGGEDPPLDTDVLVPGAPERHSP 1837
Query: 299 ------PLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVS----------SSI 342
PLR SAP APR + R I+ +P PLG VS SS+
Sbjct: 1838 IQNLDPPLRPDSGSAPPPAPRSFSGAR---IKVPNYSPSRRPLGGVSFGPLPSPGSPSSL 1894
Query: 343 F-----LQSEEKIQEARKTRFPRE-APDRTVQRARSPPF----ECRIPSEVPSRAVRPRS 392
+ + R++R P AP R SPP + R+P P+ V +
Sbjct: 1895 THHIPTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPP--PTSVVTALT 1952
Query: 393 PSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVS--SPLFPEASSEWENQNPAVEETVSR 450
P+ P G P P P++L P VS S + ++ P EE V+
Sbjct: 1953 PTSGELAPPGPAPSP--PPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAA 2010
Query: 451 RSPSPPILSQWNQCVAGERSPSLEAPSLWEI--PHSAV-ADAVEPRSSPSPPAFFPWEAP 507
+ + G+ S +P+ I P + V A + P ++P P +
Sbjct: 2011 GAMGS------SHGGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGV 2064
Query: 508 DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPST 567
D + + Q+ P S + G + PP P+E+
Sbjct: 2065 DDGTDSEAEAVQQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDL------PSEIVDFVL 2118
Query: 568 REISDLAFGGSQQSPEVAAPEPP---GSHPVGTLDADKCPEVL-------GPG-EAASGR 616
+ + GG+ E P PP GS P L A PG S
Sbjct: 2119 KNLGGPGDGGAGPREESLPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLG 2178
Query: 617 PRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAP 676
P P+P + ++ F A G G P PP + PP + P AP
Sbjct: 2179 PAPEPPKPATSKIILVNKLGQVFVKMA-GEGEPVPPP--------VKQPPLPPTISPTAP 2229
Query: 677 AHYTSVF--IKDFLPVV----PHPYEPPEP-SFDTVARDASQPNGVLRRRAENSTAKPFK 729
+T + LPVV P P PP P + + AS P +R + ++ +
Sbjct: 2230 TSWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPASPPRQAIRVKRVSTFS---- 2285
Query: 730 RTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRS 789
GR P +A + D EA P G S GG ++
Sbjct: 2286 ------------GRSPPAPPPYKAPRL---DEDGEASEDTPQVPGLGS--GGFSRVRMKT 2328
Query: 790 PVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAP----LPREPLALAGR 845
P + RPG P + SP P P P P P L + +G
Sbjct: 2329 PTVRGVLDLDRPGEPAGEESPGPLQERSPLLPLPEDGPPQVPDGPPDLLLESQWHHYSGE 2388
Query: 846 TAPAQPRAASAPPTDRSPQSPSQ 868
+ ++ S P D+ Q+P +
Sbjct: 2389 ASSSEEEPPS--PDDKENQAPKR 2409
Score = 47.8 bits (112), Expect = 5e-05
Identities = 70/252 (27%), Positives = 85/252 (33%), Gaps = 48/252 (19%)
Query: 790 PVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLP--------REPLA 841
P+ P P P P SP P P PP E + +P R PL
Sbjct: 416 PLPPPSTSPPPPLCPPPPPPVSPPPLPSPPPPPAQEEQEESPPPVVPATCSRKRGRPPLT 475
Query: 842 LAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRY-----YFV-- 894
+ R A+ AA A P SP +P+ G P V P+S + F+
Sbjct: 476 PSQR---AEREAARAGPEGTSPPTPTPST--ATGGPPEDSPTVAPKSTTFLKNIRQFIMP 530
Query: 895 -------EAPRQPRLRVLFDPESGQYVE---VLLPPSSPGPPHRVYTPLALGLGLYPPAY 944
+ PR + DP VE VL PP + PP P PP
Sbjct: 531 VVSARSSRVIKTPRRFMDEDPPKPPKVEVSPVLRPPITTSPP----VPQEPAPVPSPPRA 586
Query: 945 GPIPSLSLP-PSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSG 1003
PS +P P L P W S T LP P PAPP PP+ S
Sbjct: 587 PTPPSTPVPLPEKRRSILREPTFRWTSL------TRELP---PPPPAPP----PPPAPSP 633
Query: 1004 PTQPGKGSLFPL 1015
P P S PL
Sbjct: 634 PPAPATSSRRPL 645
Score = 40.8 bits (94), Expect = 0.007
Identities = 97/417 (23%), Positives = 145/417 (34%), Gaps = 58/417 (13%)
Query: 141 ISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPA 200
I+ PP P PA VP + P S T + L + S F + E P
Sbjct: 567 ITTSPPVPQEPAPVPSPPRAPTPPS---TPVPLPEKRRSILREPTFRWTSLTRELPPPPP 623
Query: 201 RPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKL- 259
P P P PP A + R LLLR P +A ++ L
Sbjct: 624 APPP--------PPAPSPPPAPATSSRRPLLLRA----PQFTPSEAHLKIYESVLTPPPL 671
Query: 260 -SPEAPAPSSATFGSTGRSEPETRETARSTHVVLEK---AKSRPLR--VRDNSAP----- 308
+PEAP P +EPE R R+ H+ L + + P++ V + AP
Sbjct: 672 GAPEAPEPEPPP-ADDSPAEPEPRAVGRTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNG 730
Query: 309 ----AKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFP----R 360
A+ +P +L+ + + + P P + L P S + EK + A P
Sbjct: 731 PQTQAQLLQPLQALQTQLLPQALPPPQPQ-LQPPPSPQQMPPLEKARIAGVGSLPLSGVE 789
Query: 361 EAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVR--GPRCPSPQNLSPW 418
E ++RA+ F+ + A P SP + GAV+ R P
Sbjct: 790 EKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEVAGAVKQISDRGPVRSEDESV 849
Query: 419 DRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSL 478
+ R S P P Q P ++ + + L Q V + P L
Sbjct: 850 EAKRERPSGPESPV-------QGPRIKHVCRHAAVA---LGQARAMVPE------DVPRL 893
Query: 479 WEIPHSAVAD-AVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFT 534
+P D A E SS S P + + GP + +P G G ++A T
Sbjct: 894 SALPLRDRQDLATEDTSSASETESVPSRSRRGKVEAAGPGGES--EPTGSGGTLAHT 948
Score = 37.0 bits (84), Expect = 0.094
Identities = 99/432 (22%), Positives = 131/432 (30%), Gaps = 94/432 (21%)
Query: 138 PAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGA 197
P + P PP P SP +P P PAQ E EE
Sbjct: 425 PPPLCPPPPPPVSPPPLP----------------------SPPPPPAQEE-----QEESP 457
Query: 198 APARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALAR 257
P P T ++ R RP L P Q A A
Sbjct: 458 PPVVPATCSRK----RGRP-----------------------PLTPSQRAEREAARAGPE 490
Query: 258 KLSPEAPAPSSATFGSTGRSEPETRET-ARSTHVVLEKAKS--RPLRVRDNSAPAKAPRP 314
SP P PS+AT G PE T A + L+ + P+ +S K PR
Sbjct: 491 GTSPPTPTPSTATGG-----PPEDSPTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPR- 544
Query: 315 WPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPP 374
R + D P P + PV S QE P AP P
Sbjct: 545 ------RFMDEDPPKPPKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPE 598
Query: 375 FECRIPSEVPSR---AVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFP 431
I E R R P PP P A P P+ + P + +P F
Sbjct: 599 KRRSILREPTFRWTSLTRELPPPPPAPPPPPAPSPPPAPATSSRRP-----LLLRAPQFT 653
Query: 432 EASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVE 491
+ + + + E+V +PP L +P E P + P AV
Sbjct: 654 PSEAHLK-----IYESVL----TPPPL-------GAPEAPEPEPPPADDSPAEPEPRAVG 697
Query: 492 PRSSPSPPAFFP-WEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPT 550
+ S P F P P + + +P + P + Q Q L + L PP
Sbjct: 698 RTNHLSLPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQALPPPQ 757
Query: 551 PSAPGTPEPTEM 562
P P P +M
Sbjct: 758 PQLQPPPSPQQM 769
Score = 36.2 bits (82), Expect = 0.16
Identities = 91/396 (22%), Positives = 130/396 (32%), Gaps = 75/396 (18%)
Query: 6 APPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEP-----PDVG-PDAKGPANW--- 56
AP + G ++P R+ G S +PGSP P VG PD P
Sbjct: 1856 APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDPDFPAPPRRSRR 1915
Query: 57 -----PWVAPGRGAG----AQPRLSVSAQNSRQRH-GPGSGFPRGPGSGPRPPQPQLRTL 106
P P R A P+L V S P SG PG P PP P+
Sbjct: 1916 PSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGELAPPGPAPSPPPPEDLGP 1975
Query: 107 PSGEMEVIFGVGP-----------------------LFGCSGADDREAQQQFTEP----- 138
+MEV+ G+ G S ++ ++ + P
Sbjct: 1976 DFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSHGGPGDSSEEESSPTSRYI 2035
Query: 139 ----AFISPLPPGPASPAAVPRQSQ---VPDGGSRWATYLEL-RPRGPSPAAPAQFEC-V 189
+S P++ PR Q V DG A ++ R +G P+ P V
Sbjct: 2036 HFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVVRAGV 2095
Query: 190 EVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAG 249
A + A P P +P ++ + P GA G +ESL P A
Sbjct: 2096 LGAAGDRARP--PEDLPSEIVDFVLKNLGGPGDGGA---------GPREESLPPAPPLAN 2144
Query: 250 FVQTALARKLSPEAPAPSSATF-GSTG------RSEPETRETARSTHVVLEKAKSRPLRV 302
Q + SP P + A G+ G PE + A S +++ K +++
Sbjct: 2145 GSQPSQGLTASPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKM 2204
Query: 303 RDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPV 338
P P P L I P T P GP+
Sbjct: 2205 AGEGEPVPPPVKQPPL-PPTISPTAPTSWTLPPGPL 2239
Score = 32.0 bits (71), Expect = 3.0
Identities = 69/243 (28%), Positives = 81/243 (33%), Gaps = 52/243 (21%)
Query: 3 TALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVG-------PDAKGPAN 55
+ L PP L G P P DS P PEP VG P
Sbjct: 664 SVLTPPPL-GAPEAPEPEPPPADDS----------PAEPEPRAVGRTNHLSLPRFAPVVT 712
Query: 56 WPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRG--PGSGPRPPQPQLRTLPSG---- 109
P A GA P LS Q Q P P + P PPQPQL+ PS
Sbjct: 713 TPVKAEVSPHGA-PALSNGPQTQAQLLQPLQALQTQLLPQALP-PPQPQLQPPPSPQQMP 770
Query: 110 --EMEVIFGVGPLFGCSGADDRE--------------AQQQFTEPAFISPLPPGPASPAA 153
E I GVG L SG +++ QQQ + A PL PG
Sbjct: 771 PLEKARIAGVGSL-PLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVAASMPLSPGGQMEEV 829
Query: 154 VPRQSQVPDGG---SRWATYLELRPRGPSPAAPAQ-----FECVEVALEEGAAPAR-PRT 204
Q+ D G S + R R P +P Q C A+ G A A P
Sbjct: 830 AGAVKQISDRGPVRSEDESVEAKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPED 889
Query: 205 VPK 207
VP+
Sbjct: 890 VPR 892
>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
Length = 904
Score = 68.2 bits (165), Expect = 4e-11
Identities = 142/653 (21%), Positives = 220/653 (33%), Gaps = 105/653 (16%)
Query: 214 PRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGS 273
P P+ + P P + ++ S+ E+ + + ++ + PE PS
Sbjct: 212 PAPEKKEKTPELPEPSVKVKEPSVQEAT----STSDILKVPKPEPI-PEPKEPSPEKNSK 266
Query: 274 TGRSEPETRETARSTHVVLEKAKSR------PLRVRDNSAPAKAPRPWPSLRERAIRRDK 327
+ + +TR +RS + +SR P R + + + +PR PS R R R +
Sbjct: 267 KEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRR 326
Query: 328 PAPGTEPLGP------------VSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPF 375
P P P SS L + ++R P P + +R SPP
Sbjct: 327 TPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSP---PKKPPKRTSSPPR 383
Query: 376 ECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASS 435
+ R S S R PSPP P + P+PQ TR+ + P +S
Sbjct: 384 KTRRLSPSASPPRRRHRPSPPATPP---PKTRHSPTPQQ----SNRTRKSRVSVSPGRTS 436
Query: 436 EWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSS 495
++ E+ R SPSP R L + A AD+V+ R
Sbjct: 437 GKVTKHKGTEK---RESPSP---------APKPRKVELSESEEDKGGKMAAADSVQQRRQ 484
Query: 496 PSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELA---PPTPS 552
+ Q++ G SS + ++ + E+ +PS
Sbjct: 485 ------------------YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPS 526
Query: 553 APGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPP----GSHPVGTLDADKCPEVLG 608
+P P + Q ++ G ++SP +P P P + P
Sbjct: 527 RSASPSPRKRQKETSPR------GRRRRSP---SPPPTRRRRSPSPAPPPRRRRTPTPPP 577
Query: 609 PGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEP 668
S PR P PR ++ Y+P P + + P PP S +
Sbjct: 578 RRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPK----RRASPSPPPKR 633
Query: 669 PALGPPAPAHYTSVFIKDFLPVVPHPY-EPPEPSFDTVARDASQPNGVLRRRAENSTAKP 727
P P +S K P + + + PS T + QPN +R S
Sbjct: 634 RVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN----KRHSPSPRPR 689
Query: 728 FKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGD-----GRTSPLGGA 782
+T P RR +S R + P R + P+ SP
Sbjct: 690 APQTSSSPPPV----RRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745
Query: 783 RSSSQRSPVG---PAGVRSPRPGSPQMQASPSPGIAP-----KPKTPPTAPEP 827
R SS RS G PA + P P SP SPS +P K K+P +P P
Sbjct: 746 RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSP 798
Score = 62.4 bits (150), Expect = 2e-09
Identities = 128/543 (23%), Positives = 193/543 (35%), Gaps = 80/543 (14%)
Query: 144 LPPGPA-----SPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFECVEVALEEGAA 198
+PP P SP R+S GS ++ R R P P + +
Sbjct: 332 MPPPPRHRRSRSPVRRRRRSSASLSGSS-SSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP 390
Query: 199 PARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAAAGFVQTALARK 258
A P P+R+ P PP+ +P P+ RT S+ P + + + K
Sbjct: 391 SASP---PRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEK 447
Query: 259 LSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRDN----SAPAKAPRP 314
+PAP + E + + A + V + R + + S+ ++ RP
Sbjct: 448 RESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERP 507
Query: 315 WPSLRERAI----RRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRA 370
S + RR P+ P S + +E R+ R P P R R
Sbjct: 508 KRSHVKNGEVGRRRRHSPSRSASP------SPRKRQKETSPRGRRRRSPSPPPTR---RR 558
Query: 371 RSP-----PFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRV 425
RSP P R P+ P R R+PSPP + + + R P + SP RR
Sbjct: 559 RSPSPAPPPRRRRTPTPPPRR----RTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614
Query: 426 SSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSA 485
+SP P + +P + VS SP P Q + V RSPSL +
Sbjct: 615 ASP--PPPPKRRASPSPPPKRRVS-HSPPP---KQRSSPVTKRRSPSLSS---------- 658
Query: 486 VADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEE 545
+ R SP +P PSP+ P P T
Sbjct: 659 -----KHRKGSSPSRSTREARSPQPNKRHSPSPR----PRAP-------------QTSSS 696
Query: 546 LAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPE 605
P A +P+ + SPSTR I ++ + + AA P S V + + +
Sbjct: 697 PPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQS--VRRVSSSR--S 752
Query: 606 VLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAP-PADPCGEEGGESK 664
V G E A+ +P A P P + T ++P P S P+P P +EGG K
Sbjct: 753 VSGSPEPAAKKP-PAPPSPVQSQS-PSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKK 810
Query: 665 TQE 667
++
Sbjct: 811 KKK 813
Score = 56.6 bits (135), Expect = 1e-07
Identities = 163/718 (22%), Positives = 235/718 (32%), Gaps = 131/718 (18%)
Query: 345 QSEEKIQEARKTRFPREAPDRTVQ-RARSPPFEC---RIPSEVPSRAVRPRSPSPPRQTP 400
+ E ++ ++R PR R+ R RS P R S P + RSPSP P
Sbjct: 158 EKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSP---AP 214
Query: 401 NGAVRGPRCPSP----QNLSPWDRTTR----RVSSPL-FPEASSEWENQNPAVEETVSRR 451
+ P P P + S + T+ +V P PE +N E+ +
Sbjct: 215 EKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKT 274
Query: 452 SPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPI 511
P S+ ++ RSPS P H + + + PR PSP
Sbjct: 275 RPRSRSRSK-SRSRTRSRSPSHTRPRR---RHRSRSRSYSPRRRPSPRR----------- 319
Query: 512 GTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREIS 571
PSP+ P PP P + P + S+ +S
Sbjct: 320 ---RPSPRRRTPP--------------------RRMPPPPRHRRSRSPVRRRRRSSASLS 356
Query: 572 DLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLV 631
G S S + PP P T + L P +AS R P P
Sbjct: 357 ----GSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSP--SASPPRRRHRPSP-PATPPP 409
Query: 632 KTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVV 691
KT ++P P + + P G +K + P+PA
Sbjct: 410 KTRHSPT-PQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPK------------ 456
Query: 692 PHPYEPPEPSFDT----VARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEV 747
P E E D A D+ Q RR+ + S++ + RP+
Sbjct: 457 PRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE-------DERPK- 508
Query: 748 TSRVRARGPGGENRDVEAQRLVPDGDGR---TSPLGGARSSSQRSPVGPAGVRSPRPGSP 804
S V+ G R ++ P R TSP G R RSP P
Sbjct: 509 RSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRR-------------RSPSPPPT 555
Query: 805 QMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGR-TAPAQPRAASAPPTDRSP 863
+ + SPSP P+ + PT P P +P PR R + P Q R + +PP R
Sbjct: 556 RRRRSPSPAPPPRRRRTPT-PPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614
Query: 864 QSPSQGARRQPGAAPLGKVLVD---PESGRYYFVEAPRQPRL-----------RVLFDPE 909
SP +R+ +P K V P R V R P L R +
Sbjct: 615 ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674
Query: 910 SGQYVEVLLPPSSPGPPHRVYTPLALGLGLY---------PPAYGPIPSLSLPPSP---G 957
S Q + P P P +P + G P+ PI +S P P
Sbjct: 675 SPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIK 734
Query: 958 PQALGSPQ-LPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFP 1014
A SPQ + VS + + G+ P P P+ +P ++ P P K + P
Sbjct: 735 KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSP 792
Score = 53.5 bits (127), Expect = 1e-06
Identities = 124/524 (23%), Positives = 179/524 (34%), Gaps = 91/524 (17%)
Query: 14 PRQLPTAPA----------RRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGR 63
PR++P P RR+ S+ SGS ++ S ++ P P
Sbjct: 329 PRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR--------SRSPPKKPPKRTSS 380
Query: 64 GAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFG--VGPLF 121
RLS SA R+RH P P + P Q + V G G +
Sbjct: 381 PPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVT 440
Query: 122 GCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPA 181
G + RE+ SP P P V D G + A ++ R
Sbjct: 441 KHKGTEKRESP---------SPAP----KPRKVELSESEEDKGGKMAAADSVQQRRQYRR 487
Query: 182 APAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESL 241
Q + + RP+ + E+ R + P + +P PR + S
Sbjct: 488 QNQQSSS-DSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETS---PR 543
Query: 242 GPLQAAAGFVQTALARKLSPEAP-----APSSATFGSTGRSEPETRETA--RSTHVVLEK 294
G + + T R SP P P+ T P R + R + + +
Sbjct: 544 GRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRR 603
Query: 295 AKSRPLRVRDNSAPAKAPR----PWPSLRERAIRRDKP----APGTEPLGPVSSSIFLQS 346
P R ++P P+ P P + R P +P T+ P SS +
Sbjct: 604 YSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663
Query: 347 EEKIQEARKTRFP----REAPD---RTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQT 399
+ R+ R P R +P R Q + SPP R S P R +SPSP +
Sbjct: 664 SSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRR---QSPSPSTRP 720
Query: 400 PNGAVRGPRCPSPQNL----SPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSP 455
R R P P+ + SP ++ RRVSS S E PA +++ P+P
Sbjct: 721 IR---RVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE-----PA-----AKKPPAP 767
Query: 456 PILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPP 499
P Q +SPS W P V A P SPSPP
Sbjct: 768 PSPVQ-------SQSPSTN----WS-PAVPVKKAKSPTPSPSPP 799
Score = 40.4 bits (93), Expect = 0.009
Identities = 68/282 (24%), Positives = 103/282 (36%), Gaps = 55/282 (19%)
Query: 8 PALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGAGA 67
PA P R+ PT P RR+ +P PP P R + +
Sbjct: 563 PAPPPRRRRTPTPPPRRR--------------TPSPP----------------PRRRSPS 592
Query: 68 QPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLFGCSGAD 127
R S Q +R+ P R S P PP+ + P + V P S
Sbjct: 593 PRRYSPPIQ---RRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649
Query: 128 DREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGP--SPAAPAQ 185
R + P+ S G +SP+ R+++ P R + RPR P S + P
Sbjct: 650 KRRS------PSLSSKHRKG-SSPSRSTREARSPQPNKRHSP--SPRPRAPQTSSSPPPV 700
Query: 186 FECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQ 245
+ + +P+ P T P R++ P P+ +AA +P P+ + R S G +
Sbjct: 701 RRGASSSPQRRQSPS-PSTRPIRRVSRTPEPKKIKKAA-SPSPQSVRRVSSSRSVSGSPE 758
Query: 246 AAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARS 287
AA K P P+P + ST S + A+S
Sbjct: 759 PAA---------KKPPAPPSPVQSQSPSTNWSPAVPVKKAKS 791
>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
Length = 1464
Score = 67.8 bits (164), Expect = 5e-11
Identities = 258/1063 (24%), Positives = 338/1063 (31%), Gaps = 227/1063 (21%)
Query: 5 LAPPALPGIPRQLPTAP--ARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPG 62
+ P LPG R P AP A + + G++G A G P P GP GP +P
Sbjct: 301 MGPRGLPG-ERGRPGAPGPAGARGNDGATG----AAGPPGP--TGP--AGPPGFPGAVGA 351
Query: 63 RG-AGAQPRLSVSAQNSRQRHGP-GSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPL 120
+G AG Q GP GS P+G P PP P P+G G
Sbjct: 352 KGEAGPQ--------------GPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAK 397
Query: 121 FGCSGADDREAQQQFTEPAFISPL-PPGPASPAAVPRQSQVPDG-GSRWATYLELRPRGP 178
G +GA F P P P GP P S P GS+ T + P GP
Sbjct: 398 -GANGAPGIAGAPGF--PGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP-GP 453
Query: 179 ----SPAAPAQFECVEVALEEGAAPARPRTVPKRQ---------IELRPRPQSPPRAAGA 225
P PA E A E P +R + P+ P G+
Sbjct: 454 VGVQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513
Query: 226 PRPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSAT-----FGSTGRSEPE 280
P P GS E+ P +A + A SP +P P T G GR P
Sbjct: 514 PGPAG--PKGSPGEAGRPGEAG---LPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPP 568
Query: 281 TRETARSTHVVL-----EKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPL 335
AR V+ + A P + + P P+ ++ P PG P
Sbjct: 569 GPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGP-PG--PA 625
Query: 336 GPVSSSIFLQSEEKIQEARKTRFPREAPD-RTVQRARSPPFECRIPSE--VPSRAVRPRS 392
GP R + P +P + + PP E P E VP P
Sbjct: 626 GPAGE-------------RGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPG- 671
Query: 393 PSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRS 452
P+GA RG R P +R + P P ++ + A + + +
Sbjct: 672 -------PSGA-RGERG------FPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGA 717
Query: 453 PSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIG 512
P + Q + GER + P P DA P+ + P PIG
Sbjct: 718 PGSQG-APGLQGMPGERGAA-GLPG----PKGDRGDA-GPKGADGSPGKDGVRGLTGPIG 770
Query: 513 TWGPS--PQETWD--PMGP-GSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPST 567
GP+ P + + P GP G + A G E PP P+ P + Q +
Sbjct: 771 PPGPAGAPGDKGESGPSGPAGPTGARGAPGDRG----EPGPPGPAGFAGPPGADGQPGAK 826
Query: 568 REISDLAFGGSQQSPEVAAPE-PPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRD 626
E D G P A P PPG P+G + A G S P A P
Sbjct: 827 GEPGDAGAKGDAGPPGPAGPAGPPG--PIGNVGAPGAK-----GARGSAGPPGATGFPGA 879
Query: 627 VRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKD 686
++ P G G+ P P P G+EGG+ E G P
Sbjct: 880 AGRVG--------PPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVG-------- 923
Query: 687 FLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPE 746
P PP P+ + + A P G A +R + LPG P
Sbjct: 924 -------PPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG--QRGVVGLPGQRGERGFPG 974
Query: 747 VTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSP-----RP 801
+ GP GE G+ P G + P+GP G+ P R
Sbjct: 975 LP------GPSGE-------------PGKQGPSGASGERGPPGPMGPPGLAGPPGESGRE 1015
Query: 802 GSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDR 861
G+P + SP +P K G T PA P A P
Sbjct: 1016 GAPGAEGSPGRDGSPGAKGD---------------------RGETGPAGPPGAPGAPGAP 1054
Query: 862 SPQSPS--QGARRQPG----AAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQ--- 912
P P+ G R + G A P+G V +G P+ PR E G
Sbjct: 1055 GPVGPAGKSGDRGETGPAGPAGPVGPVGARGPAG-------PQGPRGDKGETGEQGDRGI 1107
Query: 913 -----YVEVLLPPSSPGPPHRVYTPLALGLGLYPPA--YGPIPSLSLPPSPGPQALGSPQ 965
+ + PP PG P A G PA GP S P G L P
Sbjct: 1108 KGHRGFSGLQGPPGPPGSPGEQGPSGASG-----PAGPRGPPGSAGAPGKDGLNGLPGP- 1161
Query: 966 LPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPG 1008
+ GP T G P P PP GP G
Sbjct: 1162 ---IGPPGPRGRTGDAGPVGPPGPP------GPPGPPGPPSAG 1195
Score = 63.2 bits (152), Expect = 1e-09
Identities = 136/544 (25%), Positives = 171/544 (31%), Gaps = 105/544 (19%)
Query: 390 PRSPSPPRQTPNGAVRGPRCPSPQNLS--PWDRTTRRVSSPLFPEASSEWENQNPAVEET 447
P PS PR P P P PQ P + S P+ P +N E
Sbjct: 180 PMGPSGPRGLPGP----PGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEA 235
Query: 448 -----VSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADA--VEPRSSPSPPA 500
R P P ++ AG P ++ + A DA P+ P P
Sbjct: 236 GKPGRPGERGPPGPQGARGLPGTAG--LPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPG 293
Query: 501 FFPWEAPDRPIGTWGPS--PQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPE 558
+ G GP P E P PG + A + G PP P+ P P
Sbjct: 294 ------ENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAA----GPPGPTGPAGPP 343
Query: 559 PTEMQSPSTREISDLAFGGSQQSPEVAA-PEPPG----SHPVGTLDADKCPEVLGPGEAA 613
+ E GS+ V P PPG + P G AD P G A
Sbjct: 344 GFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKG----A 399
Query: 614 SGRPRMAIPRPRDVRKLVKTTYAPGFP-----AGAQGSGLPAPPADPCGEEGGESKTQEP 668
+G P +A APGFP +G QG G P P GE G +
Sbjct: 400 NGAPGIA--------------GAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDT 445
Query: 669 PALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPF 728
A G P P PP P+ + R A R T P
Sbjct: 446 GAKGEPGPVGVQG---------------PPGPAGEEGKRGA--------RGEPGPTGLPG 482
Query: 729 KRTEIRLPGALALGRRPEVTSRVRARGPGGENRDV----------EAQRL----VPDGDG 774
E PG+ P +GP GE EA R +P G
Sbjct: 483 PPGERGGPGSRGF---PGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKG 539
Query: 775 RTSPLGGARSSSQRSPVGPAGVRSPRPGSP-QMQASPSPGIAPKPKTPPTAPEPAAAVQA 833
T G + P GPAG + RPG P A G+ P A EP A +
Sbjct: 540 LTGSPGSPGPDGKTGPPGPAG-QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGER 598
Query: 834 PLPREPLALA-----GRTAPAQPRAASAPPTDRSPQSP--SQGARRQPG-AAPLGKVLVD 885
+P P A+ G P + P +R Q P S G + PG A P G+
Sbjct: 599 GVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKP 658
Query: 886 PESG 889
E G
Sbjct: 659 GEQG 662
Score = 58.9 bits (141), Expect = 2e-08
Identities = 251/1041 (24%), Positives = 310/1041 (29%), Gaps = 195/1041 (18%)
Query: 7 PPALPGIPRQL-------PTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAK----GPAN 55
PP PG P P P + G +G PG PP GP G A
Sbjct: 204 PPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKP-GRPGERGPP--GPQGARGLPGTAG 260
Query: 56 WPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIF 115
P + RG A+ GP G P PG P Q R LP GE
Sbjct: 261 LPGMKGHRGFSGLD----GAKGDAGPAGP-KGEPGSPGENGAPGQMGPRGLP-GERGRPG 314
Query: 116 GVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRP 175
GP G G D PPGP PA
Sbjct: 315 APGPA-GARGNDGATGAAG----------PPGPTGPA----------------------- 340
Query: 176 RGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQ-IELRPRPQSPPRAAG-APRPRLLLR 233
GP P P V + A P PR Q + P P P AAG A P +
Sbjct: 341 -GP-PGFPG-----AVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQ 393
Query: 234 TGSLDESLGP-LQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVL 292
G+ + P + A GF P+ P G++G EP + T
Sbjct: 394 PGAKGANGAPGIAGAPGF--PGARGPSGPQGPGGPPGPKGNSG--EPGAPGSKGDTGA-- 447
Query: 293 EKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQE 352
K + P+ V+ PA R P P E GP S + +
Sbjct: 448 -KGEPGPVGVQGPPGPA-GEEGKRGARGEPGPTGLPGPPGERGGPGSRG--FPGADGVAG 503
Query: 353 ARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSP 412
+ R +P + P E P E + + SP P+G GP P+
Sbjct: 504 PKGPAGERGSPGPA--GPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKT-GPPGPAG 560
Query: 413 QNLSPW----DRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPP--ILSQWNQCVA 466
Q+ P + FP A E V P PP + A
Sbjct: 561 QDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGV----PGPPGAVGPAGKDGEA 616
Query: 467 GERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWG-PSPQETWDPM 525
G + P A E A + P F P P G G P Q +
Sbjct: 617 GAQGPPGPAGPAGERGEQGPAGS---------PGFQGLPGPAGPPGEAGKPGEQGVPGDL 667
Query: 526 G-PGSSIAFTQEAQNGLTQEE--LAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSP 582
G PG S A + G E PP P+ P + + GSQ +P
Sbjct: 668 GAPGPSGA---RGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAP 724
Query: 583 EVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMA--IPRPRDVRKLVKTTYAPGFP 640
+ PG L K G+ P+ A P VR L PG P
Sbjct: 725 GLQG--MPGERGAAGLPGPK-------GDRGDAGPKGADGSPGKDGVRGLTGPIGPPG-P 774
Query: 641 AGA---QGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEP 697
AGA +G P+ PA P G G EP GPP PA + D P
Sbjct: 775 AGAPGDKGESGPSGPAGPTGARGAPGDRGEP---GPPGPAGFAGPPGAD-----GQPGAK 826
Query: 698 PEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPG 757
EP DA P P + PGA +R A PG
Sbjct: 827 GEPGDAGAKGDAGPPG------PAGPAGPPGPIGNVGAPGAKG--------ARGSAGPPG 872
Query: 758 GENRDVEAQRLVPDG-DGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAP 816
A R+ P G G P G + + GP G P G P P P
Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGP-AGRPGEVGPPGPPGPA 931
Query: 817 KPKTPPTAPEPAAAVQAPLP------REPLALAGRTAPAQPRAASAPPTDRSPQSPS--Q 868
K P A PA A P P R + L G+ P + Q PS
Sbjct: 932 GEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGAS 991
Query: 869 GARRQPG-AAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPH 927
G R PG P G ESGR P + G P
Sbjct: 992 GERGPPGPMGPPGLAGPPGESGREG--------------------------APGAEGSPG 1025
Query: 928 RVYTPLALG-LGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYLPVSGT 986
R +P A G G PA GP + P +PGP GP + +G
Sbjct: 1026 RDGSPGAKGDRGETGPA-GPPGAPGAPGAPGP-------------VGPAGKSGDRGETGP 1071
Query: 987 PNPAPPLLLCAPPSSSGPTQP 1007
PA P+ P + GP P
Sbjct: 1072 AGPAGPV---GPVGARGPAGP 1089
Score = 45.8 bits (107), Expect = 2e-04
Identities = 94/337 (27%), Positives = 111/337 (32%), Gaps = 51/337 (15%)
Query: 689 PVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVT 748
PV P E P D P G R A P R I PG L P
Sbjct: 93 PVCPDGSESPT---DQETTGVEGPKGDTGPRGPRGPAGPPGRDGI--PGQPGLPGPPGPP 147
Query: 749 SRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQA 808
G GG A +L D +++ GG P GP G+ P PG+P Q
Sbjct: 148 GPPGPPGLGGNF----APQLSYGYDEKST--GGISVPGPMGPSGPRGLPGP-PGAPGPQG 200
Query: 809 SPSPGIAPKPKTPPTAPEPAAAVQAPL-PREPLALAGRTAPAQPRAASAPPTDRSPQSPS 867
P P EP A+ P+ PR P G+ P +R P P
Sbjct: 201 FQGP--------PGEPGEPGAS--GPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGP- 249
Query: 868 QGARRQPGAAPL-------GKVLVDPESGRYYFVEAPRQPRLRVLFDPESG---QYVEVL 917
QGAR PG A L G +D G P P+ E+G Q
Sbjct: 250 QGARGLPGTAGLPGMKGHRGFSGLDGAKGD----AGPAGPKGEPGSPGENGAPGQMGPRG 305
Query: 918 LP-----PSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEA 972
LP P +PGP A G P GP P + G + PQ P SE
Sbjct: 306 LPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGPRGSE- 364
Query: 973 GPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPT-QPG 1008
GP V G P P P P + G QPG
Sbjct: 365 GPQG------VRGEPGPPGPAGAAGPAGNPGADGQPG 395
Score = 42.7 bits (99), Expect = 0.002
Identities = 74/284 (26%), Positives = 95/284 (33%), Gaps = 54/284 (19%)
Query: 756 PGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSP-----RPGSPQMQASP 810
PG E + E + PDG + + GP G R P R G P P
Sbjct: 82 PGAEVPEGECCPVCPDGSESPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLP 141
Query: 811 SPGIAPKPKTPP-----TAPE----------PAAAVQAPL-PREPLALAGRTAPAQPRAA 854
P P P PP AP+ +V P+ P P L G P+
Sbjct: 142 GPPGPPGPPGPPGLGGNFAPQLSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGF 201
Query: 855 SAPPTDRSPQSPS--QGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQ 912
PP + S G R PG P GK D E+G+ P +P R P+ +
Sbjct: 202 QGPPGEPGEPGASGPMGPRGPPG--PPGKNGDDGEAGK------PGRPGERGPPGPQGAR 253
Query: 913 YVEVLLPPSSPGPP----HRVYTPLALGLGLYPPA-----YGPIPSLSLPPSPGPQAL-- 961
+ P + G P HR ++ L G PA G P GP+ L
Sbjct: 254 GL-----PGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPG 308
Query: 962 --GSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSG 1003
G P P + A DG +G P P P PP G
Sbjct: 309 ERGRPGAPGPAGARGNDGA--TGAAGPPGPTGP---AGPPGFPG 347
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 67.0 bits (162), Expect = 9e-11
Identities = 262/1105 (23%), Positives = 347/1105 (31%), Gaps = 206/1105 (18%)
Query: 4 ALAPPA----LPGIPRQLPTAPARRQDSSGSSGSYYTAP--------GSPEPPDVGPDAK 51
A APPA PG+ SS SSGS+ +P PEPP+ P
Sbjct: 550 AQAPPAQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPT 609
Query: 52 GPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGS-GPRPPQPQLRTLPSGE 110
P P V P +G G P +RQ G G+P+ S PR + Q L +
Sbjct: 610 TPPV-PKVEP-KGDGIGP--------TRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQ 659
Query: 111 MEVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATY 170
+ + ++ QQ P + P PP P + AVP P A Y
Sbjct: 660 QQHQW-------------QQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPPPK--ALY 704
Query: 171 LELRPRGPSPAAPAQFE--------CVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRA 222
R P P P F+ V+ L +G P L PR +S
Sbjct: 705 PGALGR-PPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDSGG 763
Query: 223 AGAP-----RPRLLLRTGSLDESLGPLQAAAGFVQTALARKLSP-EAPAPSSATFGSTG- 275
+ + P +L G+ + P A G V TA + P +P +A G
Sbjct: 764 SSSEPFDRHAPAMLRERGT--PPVDPKLAWVGDVFTATPAEPRPLTSPLRQAADEDDKGM 821
Query: 276 RSE-----PETRETARSTHVVLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDKPAP 330
RSE P A A P+ P P PWP + + P P
Sbjct: 822 RSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQTPPP 881
Query: 331 GTEP--------LGP---------VSSSIFLQSEEKIQEARKTRF------------PRE 361
EP GP V S + + +TR+ P E
Sbjct: 882 KKEPPKEETAQLTGPEAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPPEE 941
Query: 362 --APDRTVQRARSPPFECRIPSEVPSRAVR--PRSPSPPRQTP----NGAVRGPR-CPSP 412
AP R + PP ++ E+P + + +P PP+ P G + GP+ P
Sbjct: 942 PGAPPRRAGPIKKPPPPTKV-EELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPN 1000
Query: 413 QNLSPWDRTTRRVSSPLFPEAS------SEWENQNPAVEETV---SRRSPSPPILSQWNQ 463
NLSP R R S S E+ + T R + S S
Sbjct: 1001 GNLSPAPRLRRDYSYERVGPTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREF 1060
Query: 464 CVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWD 523
R P+ P A E RS S P R T G E+
Sbjct: 1061 RGDDGRGGGTGGPNHPPAPRGRTAS--ETRSEGSEYEEIPKRRRQRGSET-GSETHES-- 1115
Query: 524 PMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPSTREI------SDLAFGG 577
+ P A T + + LTQ LAPP P AP +P P + R S GG
Sbjct: 1116 DLAPSDKEAPTPK-EGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGG 1174
Query: 578 SQQSPEV-------AAPEPPGSHPVGTLDADKCP--EVLGPGE-------AASGRPRMAI 621
+ P+V A P P G L K P E L PG ++G + +
Sbjct: 1175 GRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSNGGSNVGM 1234
Query: 622 -----PRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAP 676
PR R + + P F Q A G EG S T PA P
Sbjct: 1235 EDGERPRRRRHGRAQQQDKPPRFRRLKQERENAAR-----GSEGKPSLTL--PASAPGPE 1287
Query: 677 AHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTE---- 732
T+V V P P S D +++ Q N +E+S +R +
Sbjct: 1288 EALTTV------TVAPAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAP 1341
Query: 733 ---------IRLPGALALGRRPEVTSRVRA----RGPGGENRDVEAQRLVPDGDGRTSPL 779
+ PG G P +++ R R R +QR + R
Sbjct: 1342 PPVLLTPKAVGTPGGGGGGAVPGISAMSRGDLSQRAKDLSKRSFSSQRPGMERQNRRPGP 1401
Query: 780 GGARSSSQRSP----VGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEP-------- 827
GG SS S GP G P G + SP P + PP P P
Sbjct: 1402 GGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLPPPPPSSSA 1461
Query: 828 -----------AAAVQAPLPREPLALAGRTAP-AQPRAASAPPTDRSPQSPSQGARRQPG 875
A +Q L + TAP PR P SP R +P
Sbjct: 1462 VFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPRPPTRYEPQ 1521
Query: 876 AAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLAL 935
G + DP E P V P V P PP + P L
Sbjct: 1522 RVNSG-LSSDPH------FEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRK---PELL 1571
Query: 936 GLGLYPPAYGPIPSLSLPPSPGPQA 960
PP + S P PGPQA
Sbjct: 1572 QEESLPPPHSSGFLGSKPEGPGPQA 1596
Score = 64.3 bits (155), Expect = 6e-10
Identities = 193/886 (21%), Positives = 282/886 (31%), Gaps = 175/886 (19%)
Query: 63 RGAGAQPRLSVSAQNSRQRHGPGSGF-PR-------GPGSGPRPPQPQLRTLPSGEMEVI 114
+ AG Q + + +++ Q GPG P+ G G GP + L G +
Sbjct: 174 QAAGDQDKAAKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGH-DPR 232
Query: 115 FGVGPLFGCSGADDREAQQQFTEPAFISPLPP--GPASPAAVPRQSQVPDGGSRWATYLE 172
G+ P R F P ++ P PP GP P P PDG SR+
Sbjct: 233 GGLQPSGPPQFPPYRGMMPPFMYPPYL-PFPPPYGPQGPYRYP----TPDGPSRFPRVAG 287
Query: 173 LRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLL 232
PRG P P + +E P+ + ++ + + A
Sbjct: 288 --PRGSGP--PMRL------VEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTE 337
Query: 233 RTGSLDESLG---PLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTH 289
+ DE G + A G + A E P + G++ SEP T +TA +
Sbjct: 338 KLKFSDEEDGRDSDEEGAEGHRDSQSAS--GEERPPEADGKKGNSPNSEPPTPKTAWAE- 394
Query: 290 VVLEKAKSRPLRVRDNSAPAKAPRPWP------SLRERAIRRDKPAPGTEPLGPVSSSIF 343
SRP K P P P + D+ P +P P
Sbjct: 395 ------TSRPPETEPGPPAPKPPLPPPHRGPAGNWGPPGDYPDRGGPPCKPPAPEDEDEA 448
Query: 344 LQSEEKIQEAR------KTRFPREAPDRTVQRARSPPF--------------ECRIPSEV 383
+ K + + R RE +R +Q R + R+ +E
Sbjct: 449 WRQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEP 508
Query: 384 PSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPA 443
+ P +P+PP P + P P P S+P PE E Q P
Sbjct: 509 AAPPAAPSTPAPPPAVPK-ELPAPPAPPP------------ASAPT-PETEPEEPAQAPP 554
Query: 444 VEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFP 503
+ T + + P L + S S EA + P + EP PP P
Sbjct: 555 AQSTPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVE--PQLPSKEGPEPPEEVPPPTTPP 612
Query: 504 WEAPDRPIGTWGPSPQETWDPMG-----PGSSIAFTQEAQNGLTQEEL-----------A 547
+ GP+ Q +G F ++ Q L +++ A
Sbjct: 613 VPKVEPKGDGIGPTRQPPSQGLGYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSA 672
Query: 548 PPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVL 607
PPTP P P+P + G+ +P+ AP PP P+ L
Sbjct: 673 PPTPVPPSPPQPVTL--------------GAVPAPQ--APPPP-------------PKAL 703
Query: 608 GPGEAASGRPR-----------MAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPC 656
PG A GRP M IP D R L +P G SGL
Sbjct: 704 YPG--ALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYPPGVHPSGLVPRERSDS 761
Query: 657 GEEGGESKTQEPPAL----GPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQP 712
G E + PA+ G P P ++ D P P P + + A +
Sbjct: 762 GGSSSEPFDRHAPAMLRERGTP-PVDPKLAWVGDVFTATP---AEPRPLTSPLRQAADED 817
Query: 713 NGVLRRRA------------------ENSTAKPFKRTEIRLPGALALGRRP--EVTSRVR 752
+ +R + P R + PG L P + ++++
Sbjct: 818 DKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPGPRPLPWPPGSDEVAKIQ 877
Query: 753 ARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRS-----PRPGSPQMQ 807
P E E +L GR P G S Q P R+ PRPGS +
Sbjct: 878 TPPPKKEPPKEETAQLTGPEAGR-KPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRG 936
Query: 808 ASP-SPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPR 852
P PG P+ P P P V+ LP +PL G P P+
Sbjct: 937 IPPEEPGAPPRRAGPIKKPPPPTKVE-ELPPKPLE-QGDETPKPPK 980
Score = 61.6 bits (148), Expect = 4e-09
Identities = 201/880 (22%), Positives = 290/880 (32%), Gaps = 150/880 (17%)
Query: 129 REAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFEC 188
+ A + + P P PP P P P + P G W + RG P P E
Sbjct: 389 KTAWAETSRPPETEPGPPAPKPPLPPPHRG--PAGN--WGPPGDYPDRGGPPCKPPAPED 444
Query: 189 VEVALEE---------GAAPARPRTVPKRQIELRPRPQSPPRAAGAPR-PRLLLRTGSLD 238
+ A + A R R +R+ E R Q RAA A + RL + G+ D
Sbjct: 445 EDEAWRQRRKQSSSEISLAVERAR---RRREEEERRMQEERRAACAEKLKRLDEKFGAPD 501
Query: 239 ESLGPLQAAAGFVQT------ALARKL-SPEAPAPSSATFGSTGRSEPETRETARSTHV- 290
+ L AA + A+ ++L +P AP P+SA T EP A+ST
Sbjct: 502 KRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTP 561
Query: 291 ------VLEKAKSRPLRVRDNSAPAKAPRPWPSLRERAIRRDK-------PAPGTEPLG- 336
L S A P +E ++ P P EP G
Sbjct: 562 GVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPPEEVPPPTTPPVPKVEPKGD 621
Query: 337 -------PVSSSIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAVR 389
P S + K Q++ RF R+ ++ +++ + ++ P
Sbjct: 622 GIGPTRQPPSQGL---GYPKYQKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPT--- 675
Query: 390 PRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSE--WENQNPAVEET 447
P PSPP+ GAV P+ P P + + R P P + + W P V+
Sbjct: 676 PVPPSPPQPVTLGAVPAPQAPPPPPKALYPGALGR--PPPMPPMNFDPRWMMIPPYVDPR 733
Query: 448 VSRRSPS----PPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAV-EPRSSPSPPAFF 502
+ + P PP + + V ERS S + S P A A+ R +P
Sbjct: 734 LLQGRPPLDFYPPGVHP-SGLVPRERSDSGGSSSE---PFDRHAPAMLRERGTPPVDPKL 789
Query: 503 PWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEE--LAPPTP---SAPGTP 557
W + +P E P A E G+ E + PP P S PG P
Sbjct: 790 AWVGD-----VFTATPAEPRPLTSPLRQAA--DEDDKGMRSETPPVPPPPPYLASYPGFP 842
Query: 558 EPTEMQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDA---------DKCPEVLG 608
E P +R F + P P PPGS V + ++ ++ G
Sbjct: 843 ENGAPGPPISR------FPLEEPGPR-PLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG 895
Query: 609 PGEAASGRPRMAIPR----PRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESK 664
P A +P + P R+ +T G G+ G+P EE G
Sbjct: 896 P--EAGRKPARGVGSGGQGPPPPRRESRTETRWGPRPGSSRRGIPP-------EEPGAPP 946
Query: 665 TQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEP-PEPSFDTVAR----DASQPNGVLRRR 719
+ P PP P + K P P P+P T + + PNG L
Sbjct: 947 RRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKPDPLKITKGKLGGPKETPPNGNLSPA 1006
Query: 720 AENSTAKPFKRTEIRLPGALALGRRPEVTSRVRA-------RGPGGENRDVEAQRLVPDG 772
++R P + R E +R R RG G +R+ + R
Sbjct: 1007 PRLRRDYSYERVG---PTSCRGRGRGEYFARGRGFRGTYGGRGRGARSREFRSYREFRGD 1063
Query: 773 DGRTSPLGG--------ARSSSQRSPVGPAGVRSPR--------PGSP--QMQASPSPGI 814
DGR GG R++S+ G P+ GS + +PS
Sbjct: 1064 DGRGGGTGGPNHPPAPRGRTASETRSEGSEYEEIPKRRRQRGSETGSETHESDLAPSDKE 1123
Query: 815 APKPK-----TPPTAPEPAAAVQAPLPREPLALAGR------TAPAQPRAASAPPTDRSP 863
AP PK P AP P A +P P A GR + R PP P
Sbjct: 1124 APTPKEGTLTQVPLAPPPPGAPPSPAPARFTARGGRVFTPRGVPSRRGRGGGRPPPQVCP 1183
Query: 864 QSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLR 903
P P G + E + + P P R
Sbjct: 1184 GWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVAR 1223
Score = 59.3 bits (142), Expect = 2e-08
Identities = 205/974 (21%), Positives = 299/974 (30%), Gaps = 197/974 (20%)
Query: 129 REAQQQFTEPAFISPLPPGPASPAAV-------PRQSQVPDGGSRWATYLELRPRGPSPA 181
R Q + A +PP P+ P S VP G+ WA+ E S A
Sbjct: 41 RHGLQSLGKVAIARRMPPPANLPSLKAENKGNDPNVSLVPKDGTGWASKQEQSDPKSSDA 100
Query: 182 APAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESL 241
+ AQ P + +P Q +P+ PP AP L+ +G
Sbjct: 101 STAQ-------------PPESQPLPASQTPASNQPKRPP---AAPENTPLVPSG------ 138
Query: 242 GPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLR 301
+ Q ++ G GR+ +R L+ A +
Sbjct: 139 -----VKSWAQASVTH-----------GAHGDGGRASSLLSRFSREEFPTLQAAGDQDKA 182
Query: 302 VRDNSAPAKAPRPWPSLRER--AIRRDKPAPGTEPLGPVSSSIFLQSEEK--IQEARKTR 357
++ + ++ P PSLR + RD G + L S + + + +Q + +
Sbjct: 183 AKERESAEQSSGPGPSLRPQNSTTWRDGGGRGPDELEGPDSKLHHGHDPRGGLQPSGPPQ 242
Query: 358 FPREAPDRTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQ--TPNGAVRGPRCPSPQNL 415
FP R PPF P +P P P P + TP+G R PR P+
Sbjct: 243 FPP-------YRGMMPPF--MYPPYLPFPP--PYGPQGPYRYPTPDGPSRFPRVAGPRGS 291
Query: 416 SPWDRTTRRVSSP-------------LFPEASSEWENQNPAVEETVSRR----------S 452
P R V P L E W + V+ T +
Sbjct: 292 GPPMRLVEPVGRPSILKEDNLKEFDQLDQENDDGWAGAHEEVDYTEKLKFSDEEDGRDSD 351
Query: 453 PSPPILSQWNQCVAGE-----------RSPSLEAPSLWEIPHSAVADAVE-PRSSPSPPA 500
+ +Q +GE SP+ E P+ P +A A+ P + P PPA
Sbjct: 352 EEGAEGHRDSQSASGEERPPEADGKKGNSPNSEPPT----PKTAWAETSRPPETEPGPPA 407
Query: 501 FFPWEAPDR--PIGTWGPSPQETWDPMGP--------GSSIAFTQEAQNGLTQEELAPPT 550
P P P G WGP P + D GP A+ Q + ++ LA
Sbjct: 408 PKPPLPPPHRGPAGNWGP-PGDYPDRGGPPCKPPAPEDEDEAWRQRRKQSSSEISLAVER 466
Query: 551 PSAPGTPEPTEMQSPSTREIS------DLAFGG------SQQSPEVAAPEPPGSHPV--G 596
E MQ + D FG ++ + AAP P P
Sbjct: 467 ARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKRLKAEPAAPPAAPSTPAPPPAVPK 526
Query: 597 TLDADKCPEVLG-------PGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLP 649
L A P P E A P + P P V G +
Sbjct: 527 ELPAPPAPPPASAPTPETEPEEPAQAPPAQSTPTP-GVAAAPTLVSGGGSTSSTSSGSFE 585
Query: 650 APPADP--CGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVAR 707
A P +P +EG E + PP PP P ++ + +PP
Sbjct: 586 ASPVEPQLPSKEGPEPPEEVPPPTTPPVPK------VEPKGDGIGPTRQPPSQGLGYPKY 639
Query: 708 DASQPNGVLRRRAENSTAKPFK-RTEIRLPGALALGRRPEVTSRVRARG--PGGENRDVE 764
S P R++ E + + + + G+ P + G P +
Sbjct: 640 QKSLPPRFQRQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQPVTLGAVPAPQAPPPP 699
Query: 765 AQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTA 824
+ L P GR P+ + + P G P + P PG+ P P
Sbjct: 700 PKALYPGALGRPPPMPPMNFDPRWMMIPPYVDPRLLQGRPPLDFYP-PGVHPSGLVPRER 758
Query: 825 PEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLV 884
+ + P R APA R PP D P A +G V
Sbjct: 759 SDSGGSSSEPFDRH--------APAMLRERGTPPVD-------------PKLAWVGDV-- 795
Query: 885 DPESGRYYFVEAPRQPR-----LRVLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGL 939
F P +PR LR D E + + PP P PP+ P
Sbjct: 796 --------FTATPAEPRPLTSPLRQAAD-EDDKGMRSETPPVPPPPPYLASYP------G 840
Query: 940 YPPAYGPIPSLSLPP--SPGPQALGSPQLPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCA 997
+P P P +S P PGP+ LPW + + P P L
Sbjct: 841 FPENGAPGPPISRFPLEEPGPR-----PLPWPPGSDEVAKIQTPPPKKEPPKEETAQLTG 895
Query: 998 PPSSSGPTQPGKGS 1011
P + P + G GS
Sbjct: 896 PEAGRKPAR-GVGS 908
Score = 57.4 bits (137), Expect = 7e-08
Identities = 222/985 (22%), Positives = 320/985 (32%), Gaps = 188/985 (19%)
Query: 62 GRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLRTLPSGEMEVIFGVGPLF 121
GRG GA+ R S + R G G G G PP P+ RT E
Sbjct: 1044 GRGRGARSREFRSYREFRGDDGRGGG----TGGPNHPPAPRGRTASETRSE--------- 1090
Query: 122 GCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPA 181
G++ E ++ + + + A +++ P G+ L P G P+
Sbjct: 1091 ---GSEYEEIPKRRRQRGSETGSETHESDLAPSDKEAPTPKEGTLTQVPLAPPPPGAPPS 1147
Query: 182 -APAQFECVEVALEEGAAPARPRTVPKRQIEL--RPRPQ-----SPPRAAGAPRPRLLLR 233
APA+F G PR VP R+ RP PQ SPP + AP+
Sbjct: 1148 PAPARFTA------RGGRVFTPRGVPSRRGRGGGRPPPQVCPGWSPPAKSLAPKKP---P 1198
Query: 234 TGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSS--ATFGSTGRSEPETRETARSTHVV 291
TG L S PL+ + + LSP A S+ + G P R R+
Sbjct: 1199 TGPLPPSKEPLK------EKLIPGPLSPVARGGSNGGSNVGMEDGERPRRRRHGRAQQQD 1252
Query: 292 LEKAKSRPLRVRDNSA-----------PAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSS 340
R + R+N+A PA AP P E A+ AP S
Sbjct: 1253 KPPRFRRLKQERENAARGSEGKPSLTLPASAPGP-----EEALTTVTVAPAPRRAAAKSP 1307
Query: 341 SIFLQSEEKIQEARKTRFPREAPDRTVQRARSPPFECRIPSEVPSRAV-RPRSPSPPRQT 399
+ Q+ ++ E +T E+ D T +R R E P + P++ P
Sbjct: 1308 DLSNQNSDQANEEWETA--SESSDFTSER--------RGDKEAPPPVLLTPKAVGTPGGG 1357
Query: 400 PNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRRSPSPPILS 459
GAV G S +LS + + S + +Q P +E R P S
Sbjct: 1358 GGGAVPGISAMSRGDLSQRAKDLSKRS----------FSSQRPGMERQNRRPGPGGKAGS 1407
Query: 460 QWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQ 519
+ G P P++ PP P P P+ PS
Sbjct: 1408 SGSSSGGGGGGPGGRTGP----GRGDKRSWPSPKNRSRPPEERP---PGLPLPPPPPSSS 1460
Query: 520 ETW--------DPMGPGSSIAFTQEAQNGLT----QEELAPPTPSAPGTPEPTEMQSPST 567
+ +P G ++A Q +T P P AP P P P T
Sbjct: 1461 AVFRLDQVIHSNPAGIQQALAQLSSRQGSVTAPGGHPRHKPGLPQAPQGPSPR----PPT 1516
Query: 568 REISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDV 627
R G P P P GT P ++A P R R
Sbjct: 1517 RYEPQRVNSGLSSDPHFEEPGPMVRGVGGT-----------PRDSAGVSPFPPKRRERPP 1565
Query: 628 RK---LVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAH-YTSVF 683
RK L + + P +G GS P ES+ AL P +T+
Sbjct: 1566 RKPELLQEESLPPPHSSGFLGSKPEGPGPQ------AESRDTGTEALTPHIWNRLHTATS 1619
Query: 684 IKDFLPVVPHPY-EPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALG 742
K + P P+ EP P D + SQ + + L
Sbjct: 1620 RKSYRPSSMEPWMEPLSPFEDVAGTEMSQSDS-----------------------GVDLS 1656
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG 802
+V+S GP +QR PDG + + G + SP+ P
Sbjct: 1657 GDSQVSS-----GPC-------SQRSSPDGGLKGAAEGPPKRPGGSSPLNAVPCEGPPGS 1704
Query: 803 SPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPRE--------PLALAGRTAPAQPRAA 854
P + P+P + + P P P + + P+ + R P
Sbjct: 1705 EPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQFGT 1764
Query: 855 SAPPTD-RSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQY 913
S +D R S A ++ A+ + V + A +P+ + L +SG
Sbjct: 1765 SDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASAEPQSKNL---DSGHC 1821
Query: 914 VEVLLPPSSPGPPHRVYTPLALGLG--LYPPAYGPIPSLSLPPSPGPQALGSPQL-PWVS 970
V PSS G R+Y + G G L P+ G G+P L P+ S
Sbjct: 1822 VP---EPSSSG--QRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRPGTPSLHPYRS 1876
Query: 971 EAGPLDGTYYLPVSGTPNPAPPLLL 995
+ PL YLP P PAPP L
Sbjct: 1877 Q--PL----YLP----PGPAPPSAL 1891
Score = 54.3 bits (129), Expect = 6e-07
Identities = 205/859 (23%), Positives = 281/859 (32%), Gaps = 201/859 (23%)
Query: 61 PGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRP--PQPQLRTLPSGEMEVIFGVG 118
PG AG S+ +S G G G GPG G + P P+ R+ P E +
Sbjct: 1401 PGGKAG-------SSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGLPLP 1453
Query: 119 PLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQV--PDGGSRWATYLELRPR 176
P S A R Q + PA I A RQ V P G R L P+
Sbjct: 1454 PPPPSSSAVFRLDQVIHSNPAGIQQ-----ALAQLSSRQGSVTAPGGHPRHKPGLPQAPQ 1508
Query: 177 GPSPAAPAQFECVEVALEEGAAPARPRTVPK-RQIELRPR------PQSPPRAAGAPRPR 229
GPSP P ++E V + P P R + PR P P R PR
Sbjct: 1509 GPSPRPPTRYEPQRVNSGLSSDPHFEEPGPMVRGVGGTPRDSAGVSPFPPKRRERPPRKP 1568
Query: 230 LLLRTGSLDESLGPLQAAAGFVQTALARKLSPEAPAPSSATFGSTGRSEPETRETARSTH 289
LL+ SL P ++GF+ + PE P P + +
Sbjct: 1569 ELLQEESL-----PPPHSSGFLGS------KPEGPGPQAES------------------- 1598
Query: 290 VVLEKAKSRPLRVRDNSAPAKAPRPWPSLR----ERAIRRDKPAPGTEPLGP---VSSSI 342
RD A P W L ++ R P EPL P V+ +
Sbjct: 1599 -------------RDTGTEALTPHIWNRLHTATSRKSYRPSSMEPWMEPLSPFEDVAGTE 1645
Query: 343 FLQSEEKIQEARKTRF------PREAPDRTVQRARSPPFECRIPSEVPSRAV---RPRSP 393
QS+ + + ++ R +PD ++ A P + R P AV P
Sbjct: 1646 MSQSDSGVDLSGDSQVSSGPCSQRSSPDGGLKGAAEGPPK-RPGGSSPLNAVPCEGPPGS 1704
Query: 394 SPPRQTPNGAVRGPR--CPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEETVSRR 451
PPR+ P G R P Q L P P+ E S + S R
Sbjct: 1705 EPPRRPPPAPHDGDRKELPREQPLPP---------GPIGTERSQRTDRGTEPGPIRPSHR 1755
Query: 452 SPSPPILSQWN------QCVAGER-----------SPSLEAPSLWEIPHSAVADAVEPRS 494
P PP+ + + V G+ + ++ WE+ SA A A EP+S
Sbjct: 1756 -PGPPVQFGTSDKDSDLRLVVGDSLKAEKELTASVTEAIPVSRDWELLPSAAASA-EPQS 1813
Query: 495 SPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGP----GSSIAFTQEAQNGLTQEELAPPT 550
+ G P P + + P GS+ + + G +L P +
Sbjct: 1814 K------------NLDSGHCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNS 1861
Query: 551 PS-APGTP--EPTEMQ--------SPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLD 599
PGTP P Q +P + +S LA G G P G +
Sbjct: 1862 GGFRPGTPSLHPYRSQPLYLPPGPAPPSALLSGLALKGQFLDFSTMQATELGKLPAGGVL 1921
Query: 600 ADKCPEVLGPGEAASGRP-------RMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPA-- 650
+ P S P R +P P D T PG +G SG PA
Sbjct: 1922 YPPPSFLYSPAFCPSPLPDTSLLQVRQDLPSPSD---FYSTPLQPGGQSGFLPSGAPAQQ 1978
Query: 651 ---PPAD---PCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDT 704
P D P G PPA PPAP + LPV P +PP
Sbjct: 1979 MLLPMVDSQLPVVNFG-----SLPPA-PPPAPPPLS------LLPVGP-ALQPPSL---- 2021
Query: 705 VARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVE 764
A +P R S A+PF P +L V + P + + +
Sbjct: 2022 ----AVRPPPAPATRVLPSPARPF-------PASLGRAELHPVELK-----PFQDYQKL- 2064
Query: 765 AQRLVPDGDGRTSPLG----GARSSSQRSPVGPAGVRSPRPGSPQMQASPSPGI--APKP 818
+ L G RT P G G S + +P +GV + QASP + PKP
Sbjct: 2065 SSNLGGPGSSRTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQASPPDALRWIPKP 2124
Query: 819 ---KTPPTAPEPAAAVQAP 834
PP P+ + P
Sbjct: 2125 WERTGPPPREGPSRRAEEP 2143
>gi|116256453 nuclear receptor co-repressor 2 isoform 1 [Homo sapiens]
Length = 2524
Score = 66.2 bits (160), Expect = 1e-10
Identities = 127/507 (25%), Positives = 170/507 (33%), Gaps = 81/507 (15%)
Query: 482 PHSAVADAVEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGL 541
PH+ A ++ P PPA + P P G P P++ P P + T G
Sbjct: 754 PHTEAAKDTG-QNGPKPPATLGADGP--PPGPPTPPPEDIPAPTEPTPASEAT-----GA 805
Query: 542 TQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSP---EVAAPEPPGSHPVGTL 598
APP+PSAP P E + T + G Q+ P E+A PV
Sbjct: 806 PTPPPAPPSPSAPPPVVPKEEKEEETAAAPPVEEGEEQKPPAAEELAVDTGKAEEPV--- 862
Query: 599 DADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPA---PPADP 655
+C E G A A K K G A+ SG P A
Sbjct: 863 -KSECTEEAEEGPAKGKDAEAAEATAEGALKAEKKEGGSGRATTAKSSGAPQDSDSSATC 921
Query: 656 CGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGV 715
+E E++ + L P P+ T P+ D A + Q
Sbjct: 922 SADEVDEAEGGDKNRLLSPRPSLLT-------------------PTGDPRANASPQKPLD 962
Query: 716 LRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGR 775
L++ + + A P T++ P R ++ P Q L P+ D
Sbjct: 963 LKQLKQRAAAIPPIVTKVHEP-----PREDAAPTKPAPPAP------PPPQNLQPESDAP 1011
Query: 776 TSPLGGARSSSQRSPVGPAGVRSPR--------------PGSPQMQASPSPGIAPKP--- 818
P G + RSP PA + + PG P S P P
Sbjct: 1012 QQP-GSSPRGKSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWTSGLPFPVPPREVI 1070
Query: 819 KTPPTAPEPAAAVQAPLPREPLAL-----AGRTAPAQPRAASAPPTDRSPQSPSQGARRQ 873
K P AP+P+A AP P PL L A P P ++ PP S + PS RQ
Sbjct: 1071 KASPHAPDPSAFSYAP-PGHPLPLGLHDTARPVLPRPPTISNPPPLISSAKHPSV-LERQ 1128
Query: 874 PGAAPLGK--VLVDPESGRYYFVEAPRQPRLRVLFDPE-----SGQYVEVLLPPSSPGPP 926
GA G L P S P L + DP+ SG E L P GPP
Sbjct: 1129 IGAISQGMSVQLHVPYSEHAKAPVGPVTMGLPLPMDPKKLAPFSGVKQEQLSPRGQAGPP 1188
Query: 927 HRVYTPLALGLG-LYPPAYGPIPSLSL 952
+ P A L A G +P S+
Sbjct: 1189 ESLGVPTAQEASVLRGTALGSVPGGSI 1215
Score = 46.2 bits (108), Expect = 2e-04
Identities = 105/447 (23%), Positives = 147/447 (32%), Gaps = 85/447 (19%)
Query: 551 PSAPGTPEPTE-MQSPSTREISDLAFGGSQQSPEVAAPEPPGSHPVGTLDADKCPEVLGP 609
P+ TE + SP T D G + + A PP P
Sbjct: 739 PATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT-------------- 784
Query: 610 GEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLPAPPADPCGEEGGESKTQEPP 669
P P D+ + T A ++ +G P PP P S + PP
Sbjct: 785 ------------PPPEDIPAPTEPTPA------SEATGAPTPPPAP------PSPSAPPP 820
Query: 670 ALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFDTVARDASQPNGVLRRR-AENSTAKPF 728
+ T+ P V E P+ + +A D + ++ E + P
Sbjct: 821 VVPKEEKEEETAA-----APPVEEGEEQKPPAAEELAVDTGKAEEPVKSECTEEAEEGPA 875
Query: 729 KRTEIRLPGALALGRRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQR 788
K + A A G + + GG R A+ D +S A +
Sbjct: 876 KGKDAEAAEATAEG------ALKAEKKEGGSGRATTAKSSGAPQDSDSSATCSADEVDEA 929
Query: 789 SPVGPAGVRSPRP------GSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLAL 842
+ SPRP G P+ ASP + K A P + P P
Sbjct: 930 EGGDKNRLLSPRPSLLTPTGDPRANASPQKPLDLKQLKQRAAAIPPIVTKVHEP--PRED 987
Query: 843 AGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVL-----VDPESGRYYFVEAP 897
A T PA P APP ++ Q P A +QPG++P GK D E+ + F A
Sbjct: 988 AAPTKPAPP----APPPPQNLQ-PESDAPQQPGSSPRGKSRSPAPPADKEAEKPVFFPAF 1042
Query: 898 RQPRLRVLFDP---ESGQYVEV------LLPPSSPGPPHRVYTPLA--LGLGLYPPAYGP 946
++ DP SG V P +P P Y P L LGL+ A
Sbjct: 1043 AAEAQKLPGDPPCWTSGLPFPVPPREVIKASPHAPDPSAFSYAPPGHPLPLGLHDTAR-- 1100
Query: 947 IPSLSLPP--SPGPQALGSPQLPWVSE 971
P L PP S P + S + P V E
Sbjct: 1101 -PVLPRPPTISNPPPLISSAKHPSVLE 1126
Score = 41.6 bits (96), Expect = 0.004
Identities = 119/546 (21%), Positives = 183/546 (33%), Gaps = 122/546 (22%)
Query: 82 HGPGSGFPRGPGSGPRP--PQPQLRTLPSGEMEVIFGVG-------PLFGCSG------A 126
H G+ PRG SGP ++PS E G G G
Sbjct: 725 HASGNEVPRGECSGPATVNNSSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPT 784
Query: 127 DDREAQQQFTEPAFIS---------PLPPGP-ASPAAVPRQSQVPDGGSRWATYLELRPR 176
E TEP S P PP P A P VP++ + + + A +E
Sbjct: 785 PPPEDIPAPTEPTPASEATGAPTPPPAPPSPSAPPPVVPKEEKEEETAA--APPVEEGEE 842
Query: 177 GPSPAA------------PAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAG 224
PAA P + EC E A EEG PA+ + + ++ + G
Sbjct: 843 QKPPAAEELAVDTGKAEEPVKSECTEEA-EEG--PAKGKDAEAAEATAEGALKAEKKEGG 899
Query: 225 APRPRLLLRTGSLDESLGPLQAAAGFVQTALA----RKLSPEAPAPSSATFGSTGRSEP- 279
+ R +G+ +S +A V A R LSP P+ + T + P
Sbjct: 900 SGRATTAKSSGAPQDSDSSATCSADEVDEAEGGDKNRLLSPR-PSLLTPTGDPRANASPQ 958
Query: 280 ------ETRETARSTHVVLEKAKSRPLRVRDNSAPAK-APRPWPSLRERAIRRDKP-APG 331
+ ++ A + ++ K P R+++AP K AP P + D P PG
Sbjct: 959 KPLDLKQLKQRAAAIPPIVTKVHEPP---REDAAPTKPAPPAPPPPQNLQPESDAPQQPG 1015
Query: 332 TEPLGPVSSSIFLQSEEKIQEARKTRFPREAPDRTVQR-ARSPPFEC---RIPSEVPSRA 387
+ P G K+R P D+ ++ P F ++P + P
Sbjct: 1016 SSPRG------------------KSRSPAPPADKEAEKPVFFPAFAAEAQKLPGDPPCWT 1057
Query: 388 VRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQNPAVEET 447
P PPR+ + P P P S + P P + P +
Sbjct: 1058 SGLPFPVPPREVIKAS---PHAPDPSAFS--------YAPPGHPLPLGLHDTARPVL--- 1103
Query: 448 VSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSPPAFFPWEAP 507
P PP +S ++ + PS+ + I P S + +AP
Sbjct: 1104 -----PRPPTISNPPPLISSAKHPSVLERQIGAISQGMSVQLHVPYSEHA-------KAP 1151
Query: 508 DRPIGTWGPSPQETWDPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQSPST 567
P+ P PM P F +G+ QE+L+P + P P + P+
Sbjct: 1152 VGPVTMGLPL------PMDPKKLAPF-----SGVKQEQLSPRGQAGP----PESLGVPTA 1196
Query: 568 REISDL 573
+E S L
Sbjct: 1197 QEASVL 1202
Score = 40.8 bits (94), Expect = 0.007
Identities = 52/194 (26%), Positives = 67/194 (34%), Gaps = 30/194 (15%)
Query: 783 RSSSQRSPVGPAGVRSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLAL 842
RS+S SPV PA P P G+ P P P+ A V P P A
Sbjct: 1906 RSTSTSSPVRPAATFPPATHCPL--GGTLDGVYPTLMEPVLLPKEAPRVARP--ERPRAD 1961
Query: 843 AGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRL 902
G A+P A S SPS+G+ +P LV P SG P +
Sbjct: 1962 TGHAFLAKPPARSGL---EPASSPSKGSEPRP--------LVPPVSGHATIARTPAKNLA 2010
Query: 903 RVLFDPESGQYVEVLLPPSSPGPPHRVYT---PLAL------GLGLYPPAYGPIPSLSLP 953
P+ PP+S PHR T P ++ LG + +Y P +
Sbjct: 2011 PHHASPDPP------APPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVS 2064
Query: 954 PSPGPQALGSPQLP 967
P P LP
Sbjct: 2065 PVSSPSLTHDKGLP 2078
Score = 36.2 bits (82), Expect = 0.16
Identities = 37/155 (23%), Positives = 51/155 (32%), Gaps = 23/155 (14%)
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPG 802
+ P S A P E+ ++EA + + + +S P G +
Sbjct: 685 KAPAAASEEAAFPPVVEDEEMEASGVSGNEEEMVEEAEALHASGNEVPRGECSGPATVNN 744
Query: 803 SPQMQASPSPGI---------APKPKT------PPTAPEPAAAVQAPLPREPL----ALA 843
S ++ PSP PKP PP P P P EP A
Sbjct: 745 SSDTESIPSPHTEAAKDTGQNGPKPPATLGADGPPPGPPTPPPEDIPAPTEPTPASEATG 804
Query: 844 GRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAP 878
T P P + SAPP P P + + AAP
Sbjct: 805 APTPPPAPPSPSAPP----PVVPKEEKEEETAAAP 835
Score = 33.5 bits (75), Expect = 1.0
Identities = 25/86 (29%), Positives = 36/86 (41%), Gaps = 2/86 (2%)
Query: 782 ARSSSQRSPVGPAGVRSPRPGSP-QMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPL 840
AR R+ G A + P S + +SPS G P+P PP + A + P
Sbjct: 1953 ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGH-ATIARTPAKNLAP 2011
Query: 841 ALAGRTAPAQPRAASAPPTDRSPQSP 866
A PA P +AS P +++ P
Sbjct: 2012 HHASPDPPAPPASASDPHREKTQSKP 2037
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 65.5 bits (158), Expect = 2e-10
Identities = 93/355 (26%), Positives = 117/355 (32%), Gaps = 59/355 (16%)
Query: 638 GFPAGAQGSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHPYEP 697
G PAGA G+G PA PA EG EPP G P P P
Sbjct: 65 GSPAGAAGAG-PAAPA-----EGAPGAAPEPPPAGRARPGGGG-----------PQRPGP 107
Query: 698 PEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRARGPG 757
P P V + P LR E S + A+A G P + GP
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAG---SCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
Query: 758 ------------GENRDVEAQRLVPDGDGRTSPLGGA----RSSSQRSPV------GPAG 795
G P G G L G+ S +P GPA
Sbjct: 165 ALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224
Query: 796 VRS-PRPGSP--QMQASPSPGI----APKPKTPPTAPEPAAAVQAPLPREPLALAGRTAP 848
+ P+P +P +Q P G AP +PP AP PAA AP P P P
Sbjct: 225 LLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPP 284
Query: 849 AQP-----RAASAPPTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLR 903
P A + PP + S GA P A G V + G AP P ++
Sbjct: 285 GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP-APGVK 343
Query: 904 VLFDPESGQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIPSLSLPPSPGP 958
ES + V PP++ A + + P G +PS + P P P
Sbjct: 344 A----ESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAP 394
Score = 61.6 bits (148), Expect = 4e-09
Identities = 75/266 (28%), Positives = 85/266 (31%), Gaps = 39/266 (14%)
Query: 6 APPALP--GIPRQLPTAPARRQDSSGSSGSYYTAPGSPEPPDV----------------- 46
A PA P G P P P + G G P SP P V
Sbjct: 73 AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEG 132
Query: 47 --GPDAKGPANWPWVAPGRGAGAQPRLSVSAQNSRQRHGPGSGFPRGPGSGPRPPQPQLR 104
G A PA A A A P R GPG G GPG GP P +P
Sbjct: 133 SAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKP--- 189
Query: 105 TLPSGEMEVIFGVGPLFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGG 164
G + + G L A PA + PLP PA+P V +
Sbjct: 190 -AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPK-PAAPGTVIQTPPFVGAA 247
Query: 165 SRWATYLELRPRGPSPAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAG 224
+ A P P+PAAPA AAP P P P PP AA
Sbjct: 248 APPAPAAPSPPAAPAPAAPA------------AAPPPPPPAPATLARPPGHPAGPPTAAP 295
Query: 225 A-PRPRLLLRTGSLDESLGPLQAAAG 249
A P P GS + P AA G
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGG 321
Score = 60.8 bits (146), Expect = 6e-09
Identities = 146/572 (25%), Positives = 185/572 (32%), Gaps = 112/572 (19%)
Query: 466 AGERSPSLEAPSLWEIPHSAVADAVEPRSS----PSPPAFFPWEAPDRPIGTWGPSPQET 521
AG +P+ AP P A P P PP+ P RP+ GP+P
Sbjct: 73 AGPAAPAEGAPGA--APEPPPAGRARPGGGGPQRPGPPS------PRRPLVPAGPAPPAA 124
Query: 522 W---DPMGPGSSIAFTQEAQNGLTQEELAPPTPSAPGTPEPTEMQS-PSTREISDLAFGG 577
P G S A A E AP P+ P P ++ P G
Sbjct: 125 KLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGP-------G 177
Query: 578 SQQSPEVAAPEPPGSHPVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAP 637
P +P G TL+ +L AA+ + P + L K AP
Sbjct: 178 PGPGPGPGPGKPAGPGAAQTLNGSAA--LLNSHHAAAPAVSLVNNGPAALLPLPKPA-AP 234
Query: 638 GFPAGAQ---GSGLPAPPADPCGEEGGESKTQEPPALGPPAPAHYTSVFIKDFLPVVPHP 694
G G+ P PA P PPA PAPA P P
Sbjct: 235 GTVIQTPPFVGAAAPPAPAAP-----------SPPAA--PAPA----------APAAAPP 271
Query: 695 YEPPEPSFDTVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRAR 754
PP P+ T+AR P G TA P + G P A
Sbjct: 272 PPPPAPA--TLARPPGHPAGP-------PTAAPAVPPPAAAQNGGSAGAAPAPAPA--AG 320
Query: 755 GPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPV-------------GPAGVRSPRP 801
GP G V Q G +P G ++ S + V GPA +
Sbjct: 321 GPAG----VSGQP--GPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMV 374
Query: 802 GSPQMQ-ASPSPGIAPKPK--TPPTAPEPAA-AVQAPLPREPLALAGRTAPAQPRAASAP 857
P MQ A PSP P P TP P+ AA AV L R P A AP
Sbjct: 375 IGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAP 434
Query: 858 PTDRSPQSPSQGARRQPGAAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPESGQYVEVL 917
R PQ P Q P G VLV E+G+ + P+Q ++ + +
Sbjct: 435 ---RLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMI--PQQALAQMQAQAHAQPQTTMA 489
Query: 918 LPPSSP--GPPHRVYTPLALGLGLYPPAYGPI--------------PSLSLPPSPGPQAL 961
P++P PP ++ T A G + P PS +L SPG Q
Sbjct: 490 PRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQ-- 547
Query: 962 GSPQLPWVSEAGPLD-GTYYLPVSGTPNPAPP 992
PQL A GT +GTP P
Sbjct: 548 --PQLVLGGAAQTASLGTATAVQTGTPQRTVP 577
Score = 55.5 bits (132), Expect = 3e-07
Identities = 131/540 (24%), Positives = 170/540 (31%), Gaps = 114/540 (21%)
Query: 384 PSRAVRPRSPSPP---RQTPNGAVRGPRCPSPQNLSPWDRTTRRVSSPLFPEASSEWENQ 440
P+ +P PP R P G GP+ P P P R + P P A
Sbjct: 78 PAEGAPGAAPEPPPAGRARPGGG--GPQRPGP----PSPRRPLVPAGPAPPAAKLR---- 127
Query: 441 NPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHSAVADAVEPRSSPSP-P 499
P E + +P P + VA P+ P+ P A A P P P
Sbjct: 128 -PPPEGSAGSCAPVPAAAA-----VAAGPEPAPAGPAK---PAGPAALAARAGPGPGPGP 178
Query: 500 AFFPWEAPDRPIGTWGP----------------SPQETWDPMGPGSSIAFTQEAQNGLTQ 543
P P +P G +P + GP + + + A G
Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVI 238
Query: 544 EE------LAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQSPEVAAP----EPPGSH 593
+ APP P+AP P +P+ + P AP PPG H
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPA-----------AAPPPPPPAPATLARPPG-H 286
Query: 594 PVGTLDADKCPEVLGPGEAASGRPRMAIPRPRDVRKLVKTTYAPGFPAGAQGSGLP---- 649
P G A P V P A +G A P P A G PAG G P
Sbjct: 287 PAGPPTA--APAVPPPAAAQNGGSAGAAPAPAP---------AAGGPAGVSGQPGPGAAA 335
Query: 650 APPADPCGEEGGESKTQEPP------ALGPPAPAHYTSVFIKDFLPVVPHPYEPPEPSFD 703
A PA E + Q P A PA + V +P P P P+
Sbjct: 336 AAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPG 395
Query: 704 TVARDASQPNGVLRRRAENSTAKPFKRTEIRLPGALALGRRPEVTSRVRA-RGPGGENRD 762
T P G L + A + + RT P A G R +T V A R P
Sbjct: 396 T-------PTG-LPKGAAGAVTQSLSRT----PTATTSGIRATLTPTVLAPRLPQPPQNP 443
Query: 763 VEAQRLVPDGDGRTSPLGGARSSSQRSPVGPAGVRSPRPGSPQMQAS----PSPGIAPKP 818
Q P G S+ + + P+ QMQA P +AP+P
Sbjct: 444 TNIQNF-------QLPPGMVLVRSENGQL----LMIPQQALAQMQAQAHAQPQTTMAPRP 492
Query: 819 KTPPTAPEPAAAVQAPLPREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAP 878
TP +AP P P P+ T + S T P + Q R PG P
Sbjct: 493 ATPTSAP-PVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSATLQ---RSPGVQP 548
Score = 53.9 bits (128), Expect = 7e-07
Identities = 138/582 (23%), Positives = 195/582 (33%), Gaps = 86/582 (14%)
Query: 18 PTAPARRQDSSGSSGSYYTAPGSPEPPDVGPDAKGPANWPWVAPGRGA-GAQPRLSVSAQ 76
P P R ++G+ G++ + GSP G GPA AP GA GA P
Sbjct: 45 PRTPEVRAAAAGALGNHVVS-GSP----AGAAGAGPA-----APAEGAPGAAPE------ 88
Query: 77 NSRQRHGPGSGFPRGPGSGPR---PPQPQLRTLPSGEMEVIFGV-----GPLFGCSGADD 128
P +G R G GP+ PP P+ +P+G + G C+
Sbjct: 89 ------PPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPA 142
Query: 129 REAQQQFTEPAFISPL-PPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPSPAAPAQFE 187
A EPA P P GPA+ AA P G +P GP A
Sbjct: 143 AAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPG-PGKPAGPGAAQTLNGS 201
Query: 188 CVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDESLGPLQAA 247
+ AAPA V L P P+ P A G +++T + P A
Sbjct: 202 AALLNSHHAAAPA-VSLVNNGPAALLPLPK--PAAPGT-----VIQTPPFVGAAAPPAPA 253
Query: 248 AGFVQTA---LARKLSPEAPAPSSATFGSTGRSEPETRETARSTHVVLEKAKSRPLRVRD 304
A A A +P P P+ AT + P TA A P ++
Sbjct: 254 APSPPAAPAPAAPAAAPPPPPPAPATL-ARPPGHPAGPPTA-------APAVPPPAAAQN 305
Query: 305 NSAPAKAPRPWPSLRERAIRRDKPAPGTEPLGPVSSSIFLQSEEKIQEARKTRFPREAPD 364
+ AP P P+ A +P PG P + + +S +++ +A A
Sbjct: 306 GGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP-APGVKAESPKRVVQAAPPAAQTLAAS 364
Query: 365 RTVQRARSPPFECRIPSEVPSRAVRPRSPSPPRQTPNGAVRGPRCPSPQNLSPWDRTTRR 424
A S + +PS A P P TP G +G Q+LS RT
Sbjct: 365 GPASTAASMVIGPTMQGALPSPAA---VPPPAPGTPTGLPKGAAGAVTQSLS---RTPTA 418
Query: 425 VSSPLFPEASSEWENQNPAVEETVSRRSPSPPILSQWNQCVAGERSPSLEAPSLWEIPHS 484
+S + + P V + P P Q Q G E L IP
Sbjct: 419 TTSGIRATLT-------PTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQ 471
Query: 485 AVADA-----VEPRSSPSPPAFFPWEAPDRPIGTWGPSPQETWDPMGPGSSIAFTQEAQN 539
A+A +P+++ +P P AP I T PG+ I Q
Sbjct: 472 ALAQMQAQAHAQPQTTMAPRPATPTSAPPVQIST----------VQAPGTPIIARQ---- 517
Query: 540 GLTQEELAPPTPSAPGTPEPTEMQSPSTREISDLAFGGSQQS 581
+T + A T +P+ S L GG+ Q+
Sbjct: 518 -VTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQT 558
Score = 52.8 bits (125), Expect = 2e-06
Identities = 76/299 (25%), Positives = 97/299 (32%), Gaps = 33/299 (11%)
Query: 743 RRPEVTSRVRARGPGGENRDVEAQRLVPDGDGRTSPLGGARSSSQRSPV------GPAGV 796
R PEV R A G G N V G G +P GA ++ P G G
Sbjct: 46 RTPEV--RAAAAGALG-NHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGP 102
Query: 797 RSPRPGSPQMQASPSPGIAPKPKTPPTAPEPAAAVQAPLPREPLALAG-RTAPAQPRAAS 855
+ P P SP+ P+ P K P PE +A AP+P AG APA P +
Sbjct: 103 QRPGPPSPRRPLVPAGPAPPAAKLRP-PPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPA 161
Query: 856 APPTDRSPQSPSQGARRQPG-----AAPLGKVLVDPESGRYYFVEAPRQPRLRVLFDPES 910
P + P G PG P G +G + + V
Sbjct: 162 GPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNG 221
Query: 911 GQYVEVLLPPSSPGPPHRVYTPLALGLGLYPPAYGPIP----------SLSLPPSPGPQA 960
+ L P++PG + TP +G P P P + PP P P
Sbjct: 222 PAALLPLPKPAAPGTV--IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPAT 279
Query: 961 LGSPQ-----LPWVSEAGPLDGTYYLPVSGTPNPAPPLLLCAPPSSSGPTQPGKGSLFP 1014
L P P + A P S PAP P SG PG + P
Sbjct: 280 LARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAP 338
Score = 37.4 bits (85), Expect = 0.072
Identities = 66/271 (24%), Positives = 92/271 (33%), Gaps = 38/271 (14%)
Query: 4 ALAPPALPGIPRQLPTAPARRQDSSGSSGSYYTAPGSPE-PPDVGPDAKGPANWPWVAPG 62
A AP A P P APA + PG P PP P PA G
Sbjct: 260 APAPAAPAAAPPPPPPAPA----------TLARPPGHPAGPPTAAPAVPPPAA---AQNG 306
Query: 63 RGAGAQPRLSVSAQNSRQRHGPG--SGFPRGPGSGPRPPQPQLRT-LPSGEMEVIFGVGP 119
AGA P + +A GP SG P GPG+ P P ++ P ++
Sbjct: 307 GSAGAAPAPAPAA------GGPAGVSGQP-GPGAAAAAPAPGVKAESPKRVVQAAPPAAQ 359
Query: 120 LFGCSGADDREAQQQFTEPAFISPLPPGPASPAAVPRQSQVPDGGSRWATYLELRPRGPS 179
SG A GP A+P + VP T L P+G +
Sbjct: 360 TLAASGPASTAASMVI-----------GPTMQGALPSPAAVPPPAPGTPTGL---PKGAA 405
Query: 180 PAAPAQFECVEVALEEGAAPARPRTVPKRQIELRPRPQSPPRAAGAPRPRLLLRTGSLDE 239
A A G TV ++ P+ + + P +L+R+ +
Sbjct: 406 GAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQL 465
Query: 240 SLGPLQAAAGFVQTALARKLSPEAPAPSSAT 270
+ P QA A A A+ + AP P++ T
Sbjct: 466 LMIPQQALAQMQAQAHAQPQTTMAPRPATPT 496
Score = 32.0 bits (71), Expect = 3.0
Identities = 57/213 (26%), Positives = 71/213 (33%), Gaps = 42/213 (19%)
Query: 836 PREPLALAGRTAPAQPRAASAPPTDRSPQSPSQGARRQPGAAPL------------GKVL 883
PR P A S P + P+ A PGAAP G
Sbjct: 45 PRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQR 104
Query: 884 VDPESGRYYFVEA-PRQPRLRVLFDPE--SGQYVEVLL-------PPSSPGPPHRVYTPL 933
P S R V A P P ++ PE +G V P +P P + P
Sbjct: 105 PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164
Query: 934 ALGLGLYPPAYGPIPSLSLPPSPGPQALGSPQLPWVSEAGPLDGTYYL--------PVSG 985
AL P GP P P PGP G P P ++ L+G+ L P
Sbjct: 165 ALAARAGP---GPGPGPGPGPGPGP---GKPAGPGAAQT--LNGSAALLNSHHAAAPAVS 216
Query: 986 TPNPAPPLLLCAP-PSSSG---PTQPGKGSLFP 1014
N P LL P P++ G T P G+ P
Sbjct: 217 LVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.132 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,070,385
Number of Sequences: 37866
Number of extensions: 4628007
Number of successful extensions: 44354
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 321
Number of HSP's successfully gapped in prelim test: 2336
Number of HSP's that attempted gapping in prelim test: 21277
Number of HSP's gapped (non-prelim): 17158
length of query: 1015
length of database: 18,247,518
effective HSP length: 112
effective length of query: 903
effective length of database: 14,006,526
effective search space: 12647892978
effective search space used: 12647892978
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.