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Search of human proteins with 238908499
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|238908499 sciellin isoform 1 [Homo sapiens]
(688 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|238908499 sciellin isoform 1 [Homo sapiens] 1383 0.0
gi|238908497 sciellin isoform 2 [Homo sapiens] 1332 0.0
gi|238908501 sciellin isoform 3 [Homo sapiens] 1264 0.0
gi|148298722 zinc finger protein 185 [Homo sapiens] 70 5e-12
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 58 3e-08
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 56 1e-07
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 55 3e-07
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 55 3e-07
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 55 3e-07
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 55 3e-07
gi|14249338 BUD13 homolog isoform 1 [Homo sapiens] 45 2e-04
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 45 3e-04
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 45 3e-04
gi|71061468 centromere protein E [Homo sapiens] 41 0.003
gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens] 41 0.004
gi|45827753 transforming, acidic coiled-coil containing protein ... 41 0.004
gi|11119414 transforming, acidic coiled-coil containing protein ... 41 0.004
gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo ... 41 0.004
gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo s... 41 0.004
gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo sa... 41 0.004
gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens] 40 0.007
gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens] 40 0.007
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 40 0.009
gi|239757861 PREDICTED: similar to armadillo repeat containing, ... 40 0.009
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 40 0.009
gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens] 39 0.012
gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens] 39 0.012
gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens] 39 0.012
gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens] 39 0.012
gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens] 39 0.012
>gi|238908499 sciellin isoform 1 [Homo sapiens]
Length = 688
Score = 1383 bits (3580), Expect = 0.0
Identities = 688/688 (100%), Positives = 688/688 (100%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
Query: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
Query: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
Query: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
Query: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
Query: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
Query: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
Query: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
Query: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
>gi|238908497 sciellin isoform 2 [Homo sapiens]
Length = 668
Score = 1332 bits (3448), Expect = 0.0
Identities = 667/688 (96%), Positives = 667/688 (96%), Gaps = 20/688 (2%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI
Sbjct: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNI---------- 230
Query: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
EELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 231 ----------SEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 280
Query: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 281 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 340
Query: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 341 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 400
Query: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 401 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 460
Query: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 461 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 520
Query: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 521 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 580
Query: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 581 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 640
Query: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 641 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 668
>gi|238908501 sciellin isoform 3 [Homo sapiens]
Length = 646
Score = 1264 bits (3272), Expect = 0.0
Identities = 644/688 (93%), Positives = 644/688 (93%), Gaps = 42/688 (6%)
Query: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR
Sbjct: 1 MSNVTLRKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGR 60
Query: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR
Sbjct: 61 VVLNRHNSHDALDRKVNERDVPKATISRYSSDDTLDRISDRNDAAKTYKANTLDNQLTNR 120
Query: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPPPGYNASSSTGTR 180
SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR
Sbjct: 121 SMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKR-------------------- 160
Query: 181 RREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 240
EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK
Sbjct: 161 --EPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVK 218
Query: 241 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 300
VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT
Sbjct: 219 VATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRT 278
Query: 301 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 360
DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG
Sbjct: 279 DKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKG 338
Query: 361 HENTTGKKDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 420
HE N T GQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT
Sbjct: 339 HE--------------------NTTGGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGT 378
Query: 421 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 480
EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK
Sbjct: 379 EKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVK 438
Query: 481 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 540
NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN
Sbjct: 439 NTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRN 498
Query: 541 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 600
TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS
Sbjct: 499 TNRDQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENIS 558
Query: 601 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 660
GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL
Sbjct: 559 GKYIQTVYSTSDRSVIERDMCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENL 618
Query: 661 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 688
QAGDSIWIYRQTIHCEPCYSKIMAKWIP
Sbjct: 619 QAGDSIWIYRQTIHCEPCYSKIMAKWIP 646
>gi|148298722 zinc finger protein 185 [Homo sapiens]
Length = 689
Score = 70.5 bits (171), Expect = 5e-12
Identities = 30/63 (47%), Positives = 41/63 (65%), Gaps = 2/63 (3%)
Query: 620 MCTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 679
+CTYC + + K+ L+ L ICCH CFKC IC +P+ +L D I+I+R TIHC CY
Sbjct: 628 ICTYCNREIRDCPKITLEHLGICCHEYCFKCGICSKPMGDLL--DQIFIHRDTIHCGKCY 685
Query: 680 SKI 682
K+
Sbjct: 686 EKL 688
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 57.8 bits (138), Expect = 3e-08
Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 6/119 (5%)
Query: 561 KNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVYSTSDRSVIERDM 620
+N SS+ AG T + T V ++SP + S Q+ +RSV + +
Sbjct: 1226 RNPSSSVPPPSAGSVKT---STTGVATTQSPTP---RSHSPSASQSGSQLRNRSVSGKRI 1279
Query: 621 CTYCRKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCY 679
C+YC LG MI++ L +C H CFKC C+ L +G + I ++C CY
Sbjct: 1280 CSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCY 1338
Score = 29.6 bits (65), Expect = 9.7
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 9/68 (13%)
Query: 7 RKMSPTGNEMKSTTQGTTRKQQDFHEVNKRRTFLQDNSWIKKRPEEEKDENYGRV-VLNR 65
++ P+G E++ +QQ E+ KR DNSWI++R E ++ R
Sbjct: 1122 KEQVPSGAELE--------RQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1173
Query: 66 HNSHDALD 73
S D LD
Sbjct: 1174 GESLDNLD 1181
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 55.8 bits (133), Expect = 1e-07
Identities = 29/94 (30%), Positives = 47/94 (50%), Gaps = 1/94 (1%)
Query: 589 KSPKDGYQENISGKYIQTVYSTS-DRSVIERDMCTYCRKPLGVETKMILDELQICCHSTC 647
KSP++ +Q T S +RS+ + +C+ C PLG MI++ L + H C
Sbjct: 980 KSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQC 1039
Query: 648 FKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
F+C ICK L + +G + I ++C CY +
Sbjct: 1040 FRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1073
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 710 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 764
Query: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 765 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 823
Query: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 824 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 880
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 722 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 776
Query: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 777 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 835
Query: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 836 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 892
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 876 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 930
Query: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 931 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 989
Query: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 990 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1046
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 54.7 bits (130), Expect = 3e-07
Identities = 43/177 (24%), Positives = 75/177 (42%), Gaps = 24/177 (13%)
Query: 523 QSQDLDNLIKVKPSALRNTNRDQNLENLIE---------VNSHVSENKNGSSNTGAKQAG 573
Q D D L+K R ++R + +L E V+ V E+ + GA G
Sbjct: 877 QGDDSDLLLKT-----RESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCG 931
Query: 574 PQDTVVYTRTYVENSKSPKDGYQENISGKYI-------QTVYSTSDR--SVIERDMCTYC 624
+ + + + +P E++ K + + S S+R S+ + +C+ C
Sbjct: 932 TNPQLAQDPSQNQQTSNPTHS-SEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSC 990
Query: 625 RKPLGVETKMILDELQICCHSTCFKCEICKQPLENLQAGDSIWIYRQTIHCEPCYSK 681
PLG MI++ L + H CF+C ICK L + +G + I ++C CY +
Sbjct: 991 GLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMR 1047
>gi|14249338 BUD13 homolog isoform 1 [Homo sapiens]
Length = 619
Score = 45.1 bits (105), Expect = 2e-04
Identities = 82/401 (20%), Positives = 149/401 (37%), Gaps = 51/401 (12%)
Query: 150 TSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKP------SSPVSSPNQ 203
+S T+P ++ R P PP +S+G R P P P SS +SSP
Sbjct: 184 SSDTSPPRRARHDSPDPSPPRRPQHNSSGASPRRVRHDSPDPSPPRRARHGSSDISSP-- 241
Query: 204 LRQDNRQIHPPKPGVYTETNRSAE----RNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 259
R++H P T S++ R R D V SL R+ G+ +
Sbjct: 242 -----RRVHNNSPDTSRRTLGSSDTQQLRRARHDSPDLAPNVTYSLPRTKSGKAPERASS 296
Query: 260 MNKSLNRNQGLDSL-FRANPKVE-------EREKRAKSLESLIYMSTRTDKDGKGIQSLG 311
+ G L F N K E R+K+AKS + + D KG
Sbjct: 297 KTSPHWKESGASHLSFPKNSKYEYDPDISPPRKKQAKS-----HFGDKKQLDSKGDCQKA 351
Query: 312 SPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENT-TGKKDL 370
+ ++ K G Q+ +S ++ N+ RS D D + P+ + T + DL
Sbjct: 352 TDSDLSSPRHKQSPGHQDSDS--DLSPPRNRPRHRSSDSDLSP---PRRRQRTKSSDSDL 406
Query: 371 DGLIKVDPETNK------NITRGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKST 424
+ P K G L ++ + E+K +Q + + Y T
Sbjct: 407 SPPRRSQPPGKKAAHMYSGAKTGLVLTDIQREQQELKEQDQETMAFEAEFQ-YAETVFRD 465
Query: 425 EGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIP--SANKSSEQGLDEHINVSPKAVKNT 482
+ G+ + ++ +R + + ++ E + + ++ +Q +++ + K +
Sbjct: 466 KSGRKRNLKLERLEQRRKAEKDSERDELYAQWGKGLAQSRQQQQNVEDAMKEMQKPLARY 525
Query: 483 DGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQ 523
+DLD++++ + +AN IK N A N+
Sbjct: 526 IDDEDLDRMLR------EQEREGDPMANFIKKNKAKENKNK 560
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 44.7 bits (104), Expect = 3e-04
Identities = 80/434 (18%), Positives = 167/434 (38%), Gaps = 56/434 (12%)
Query: 178 GTRRREPGVHPPIP------PKPSSPVSSPNQLRQDN-----RQIHPPKPGVYTETNRSA 226
G R R P PPI PK + SS + + + R+ H + ET
Sbjct: 1013 GERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVK 1072
Query: 227 ERNIR---SQDLDN---IVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANP-- 278
E ++ S+D+ + K + + ++K + LDN + K +G+D F ++
Sbjct: 1073 EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMK 1132
Query: 279 --KVEERE-----KRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLE 331
K+E E + K M +KD + + IK+N+ T K +N+
Sbjct: 1133 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENIS 1192
Query: 332 SVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLD 391
+ + + ++ TS + + +V K TG + + VD T+ + T G +
Sbjct: 1193 NTKEPSEKLESTSSKVKQ----EKVKGKVRRKVTGTEGSSSTL-VD-YTSTSSTGGSPVR 1246
Query: 392 NLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLE 451
+ T + + ++ NN +T + + +I+V + + + E
Sbjct: 1247 KSEEKTDTKRTVIKTMEEYNN---------DNTAPAEDVIIMIQVPQSKWDKDDFESEEE 1297
Query: 452 NLIKVIPSANKSSEQGLDEHINVSPKAV-----KNTDGKQDLDKLIK-VNPEIFTNNQRN 505
++ P ++ + ++++ P + K ++ + + K K V+ EI + ++
Sbjct: 1298 DVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKS 1357
Query: 506 QDLANLIKVNPAVIRNNQSQDLDN--LIKVKPSALRNTNRDQNLENLIEVNSHVSENKNG 563
N A +++D D L K P +N+ + + NL +N +
Sbjct: 1358 SK-------NSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS 1410
Query: 564 SSNTGAKQAGPQDT 577
S+ A+ + D+
Sbjct: 1411 QSSKEARTSDKHDS 1424
Score = 33.9 bits (76), Expect = 0.52
Identities = 80/407 (19%), Positives = 155/407 (38%), Gaps = 39/407 (9%)
Query: 193 KPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGE 252
KP+S + + + + N +P K +E + +++ + + + VK + + S+KG+
Sbjct: 1310 KPASVIKNVST-KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1368
Query: 253 ELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGS 312
D + L + NP+ + + + +L R ++ G +SL
Sbjct: 1369 TKD------------RDYSVLEKENPEKRKNSTQPEKESNL----DRLNEQGN-FKSLSQ 1411
Query: 313 PIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDG 372
K + +DK++ R + N R KT + + ++ + K T +KD
Sbjct: 1412 SSKEARTSDKHDSTRASSNKDFTPN-RDKKTDYDTREYSSSKRRDEKNE--LTRRKDSPS 1468
Query: 373 LIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQG-SKDLN-NFIKVYPGTEKSTEGGQSL 430
K KN R + D K T + K+SN S+D + K T++ E +S+
Sbjct: 1469 RNKDSASGQKNKPR-EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1527
Query: 431 DSLIKVTPER-------NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTD 483
D E+ N+ + GN+ L L K G + V PK +
Sbjct: 1528 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1587
Query: 484 GKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNR 543
+ D + + F + D + + V N S+DL + I K
Sbjct: 1588 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK------- 1640
Query: 544 DQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKS 590
++L+ V +S N++ SS + + + TR++ ++ S
Sbjct: 1641 -ESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1686
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 44.7 bits (104), Expect = 3e-04
Identities = 80/434 (18%), Positives = 167/434 (38%), Gaps = 56/434 (12%)
Query: 178 GTRRREPGVHPPIP------PKPSSPVSSPNQLRQDN-----RQIHPPKPGVYTETNRSA 226
G R R P PPI PK + SS + + + R+ H + ET
Sbjct: 1047 GERERSPRSEPPIKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVK 1106
Query: 227 ERNIR---SQDLDN---IVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANP-- 278
E ++ S+D+ + K + + ++K + LDN + K +G+D F ++
Sbjct: 1107 EEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKGEKRKRKTEEKGVDKDFESSSMK 1166
Query: 279 --KVEERE-----KRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLE 331
K+E E + K M +KD + + IK+N+ T K +N+
Sbjct: 1167 ISKLEVTEIVKPSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENIS 1226
Query: 332 SVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQSLD 391
+ + + ++ TS + + +V K TG + + VD T+ + T G +
Sbjct: 1227 NTKEPSEKLESTSSKVKQ----EKVKGKVRRKVTGTEGSSSTL-VD-YTSTSSTGGSPVR 1280
Query: 392 NLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLE 451
+ T + + ++ NN +T + + +I+V + + + E
Sbjct: 1281 KSEEKTDTKRTVIKTMEEYNN---------DNTAPAEDVIIMIQVPQSKWDKDDFESEEE 1331
Query: 452 NLIKVIPSANKSSEQGLDEHINVSPKAV-----KNTDGKQDLDKLIK-VNPEIFTNNQRN 505
++ P ++ + ++++ P + K ++ + + K K V+ EI + ++
Sbjct: 1332 DVKSTQPISSVGKPASVIKNVSTKPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKS 1391
Query: 506 QDLANLIKVNPAVIRNNQSQDLDN--LIKVKPSALRNTNRDQNLENLIEVNSHVSENKNG 563
N A +++D D L K P +N+ + + NL +N +
Sbjct: 1392 SK-------NSASSEKGKTKDRDYSVLEKENPEKRKNSTQPEKESNLDRLNEQGNFKSLS 1444
Query: 564 SSNTGAKQAGPQDT 577
S+ A+ + D+
Sbjct: 1445 QSSKEARTSDKHDS 1458
Score = 33.9 bits (76), Expect = 0.52
Identities = 80/407 (19%), Positives = 155/407 (38%), Gaps = 39/407 (9%)
Query: 193 KPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGE 252
KP+S + + + + N +P K +E + +++ + + + VK + + S+KG+
Sbjct: 1344 KPASVIKNVST-KPSNIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGK 1402
Query: 253 ELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGS 312
D + L + NP+ + + + +L R ++ G +SL
Sbjct: 1403 TKD------------RDYSVLEKENPEKRKNSTQPEKESNL----DRLNEQGN-FKSLSQ 1445
Query: 313 PIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDG 372
K + +DK++ R + N R KT + + ++ + K T +KD
Sbjct: 1446 SSKEARTSDKHDSTRASSNKDFTPN-RDKKTDYDTREYSSSKRRDEKNE--LTRRKDSPS 1502
Query: 373 LIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQG-SKDLN-NFIKVYPGTEKSTEGGQSL 430
K KN R + D K T + K+SN S+D + K T++ E +S+
Sbjct: 1503 RNKDSASGQKNKPR-EERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKRPNEETKSV 1561
Query: 431 DSLIKVTPER-------NRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTD 483
D E+ N+ + GN+ L L K G + V PK +
Sbjct: 1562 DKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQVEKEQITGQIDKSTVKPKPQLSHS 1621
Query: 484 GKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNR 543
+ D + + F + D + + V N S+DL + I K
Sbjct: 1622 SRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEESSGNISKDLKDKIVEKAK------- 1674
Query: 544 DQNLENLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKS 590
++L+ V +S N++ SS + + + TR++ ++ S
Sbjct: 1675 -ESLDTAAVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSSSASS 1720
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 41.2 bits (95), Expect = 0.003
Identities = 88/482 (18%), Positives = 187/482 (38%), Gaps = 25/482 (5%)
Query: 32 EVNKRRTFLQDNSWIKKRPEEEKDENYGRVVLNRHNSHDALDRKVNERDVPKATISRY-S 90
EV + R +QD S EKD+ + VV L+ +D T S Y S
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKS 814
Query: 91 SDDTLDRISDRN-DAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPG-GSLNANTS-NTI 147
+D + D + YK +N+ N+ + S E K G+L S T
Sbjct: 815 TDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNL-SKEAQKFDSSLGALKTELSYKTQ 873
Query: 148 ASTSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQD 207
T V+++ N S+ T RE + + V + Q + D
Sbjct: 874 ELQEKTREVQERLNEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD 933
Query: 208 NRQIHPPKPGVYTETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK--MNKSLN 265
+Q+ + + +S + + ++D ++ +L+ + +E N +K +++ ++
Sbjct: 934 LKQLQESLQ-IERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVS 992
Query: 266 RNQGLDSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEK 325
RN ++ E + + + ++ + + D + K Q+L + +K N+ ++ K
Sbjct: 993 RNLHMEE--------NTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRK 1044
Query: 326 GRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNIT 385
++ ++ + E L + N E T ++ L+ + + + I
Sbjct: 1045 IFSLIQEKNELQQMLESVIAEKEQLKTDLKENI---EMTIENQEELRLLGDELKKQQEIV 1101
Query: 386 RGQSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQ 445
Q ++ IK E+ R+ ++ +K EKS + + L+ V E + +
Sbjct: 1102 -AQEKNHAIKKEGELSRTCDRLAEVEEKLK-----EKSQQLQEKQQQLLNVQEEMSEMQK 1155
Query: 446 GNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRN 505
++ENL + + + E E + ++ K +N + + + K KV E+ + +
Sbjct: 1156 KINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETE 1215
Query: 506 QD 507
+D
Sbjct: 1216 RD 1217
>gi|116256485 chromosome 6 open reading frame 10 [Homo sapiens]
Length = 563
Score = 40.8 bits (94), Expect = 0.004
Identities = 101/474 (21%), Positives = 175/474 (36%), Gaps = 48/474 (10%)
Query: 117 LTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKKRQSWFPPPP-----PGY 171
L+ S+ + L+ T+ P + A T AT P+K +++ P PG
Sbjct: 111 LSRSSIGSIKCLQTTEEPPSRTAGAMMQFTAPIPGATGPIKLSQKTIVQTPGPIVQYPGS 170
Query: 172 NASSSTGTRRREPGVHPPIPPKPSSPVSS--PNQLRQDNRQIHPPKPGVYTETNRSAERN 229
NA + R PP+ P S ++ P D+ P V E
Sbjct: 171 NAGPPSAPR------GPPMAPIIISQRTARIPQVHTMDSSGKITLTPVVILTGYMDEELA 224
Query: 230 IRSQDLDNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKS 289
+S I+K + + + EE N + + ++SL A+ K ERE +
Sbjct: 225 KKSCSKIQILKCGGTARSQNSREE--NKEALKNDIIFTNSVESLKSAHIKEPEREGKGTD 282
Query: 290 LE-SLIYMSTRTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRSE 348
LE I M + D D + + +K+++ + +G Q +SV+ V ++SE
Sbjct: 283 LEKDKIGMEVKVDSDAGIPKRQETQLKISEMSIPQGQGAQIKKSVSDVPRGQESQVKKSE 342
Query: 349 DLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKN---ITRGQSLDNLIKVTPEVKRSNQ 405
PKG E K L L + + K+ + R Q +VK+S
Sbjct: 343 ------SGVPKGQEAQVTKSGLVVLKGQEAQVEKSEMGVPRRQE--------SQVKKSQS 388
Query: 406 G-SKDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKSS 464
G SK +K + Q S +KV + + Q + ++ K K S
Sbjct: 389 GVSKGQEAQVKKRESVVLKGQEAQVEKSELKV--PKGQEGQVEKTEADVPKEQEVQEKKS 446
Query: 465 EQGLDEHINVSPKAVKNTDGK--QDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNN 522
E G+ + VKNT+ + L+ +K + Q Q+ + +
Sbjct: 447 EAGV---LKGPESQVKNTEVSVPETLESQVKKSESGVLKGQEAQEKKESFE-DKGNNDKE 502
Query: 523 QSQDLDNLIKVKPSALRNTNRDQNLENL-----IEVNSHVSE-NKNGSSNTGAK 570
+ +D + K +NT D+ + + E+N S+ +K +NTG K
Sbjct: 503 KERDAEKDPNKKEKGDKNTKGDKGKDKVKGKRESEINGEKSKGSKRAKANTGRK 556
>gi|45827753 transforming, acidic coiled-coil containing protein 2
isoform c [Homo sapiens]
Length = 996
Score = 40.8 bits (94), Expect = 0.004
Identities = 60/241 (24%), Positives = 83/241 (34%), Gaps = 41/241 (17%)
Query: 135 PGGSLNANTSNTIASTS--------ATTPVKKKRQSWFPPPPPGY--NASSSTGTRRREP 184
P LN S ++S S +TTPVK PPPPP ST EP
Sbjct: 11 PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAP--PPPPPEVIPEPEVSTQPPPEEP 68
Query: 185 GVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKP------GVYTETNRSAERNIRSQDLDNI 238
G P P P R D+ + P +P V+ E A + D DNI
Sbjct: 69 GCGSETVPVPDGP-------RSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI 121
Query: 239 VKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMST 298
V T + + N + K R + DS+ P + R+ SL++
Sbjct: 122 ELVDTFQTLEPRASDAKN--QEGKVNTRRKSTDSV----PISKSTLSRSLSLQA------ 169
Query: 299 RTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTS-RRSEDLDNATEVN 357
D G S G+P V D G + S K + S ++ + TE
Sbjct: 170 ---SDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 226
Query: 358 P 358
P
Sbjct: 227 P 227
>gi|11119414 transforming, acidic coiled-coil containing protein 2
isoform d [Homo sapiens]
Length = 1026
Score = 40.8 bits (94), Expect = 0.004
Identities = 60/241 (24%), Positives = 83/241 (34%), Gaps = 41/241 (17%)
Query: 135 PGGSLNANTSNTIASTS--------ATTPVKKKRQSWFPPPPPGY--NASSSTGTRRREP 184
P LN S ++S S +TTPVK PPPPP ST EP
Sbjct: 11 PASDLNLEASEAMSSDSEEAFETPESTTPVKAPPAP--PPPPPEVIPEPEVSTQPPPEEP 68
Query: 185 GVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKP------GVYTETNRSAERNIRSQDLDNI 238
G P P P R D+ + P +P V+ E A + D DNI
Sbjct: 69 GCGSETVPVPDGP-------RSDSVEGSPFRPPSHSFSAVFDEDKPIASSGTYNLDFDNI 121
Query: 239 VKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIYMST 298
V T + + N + K R + DS+ P + R+ SL++
Sbjct: 122 ELVDTFQTLEPRASDAKN--QEGKVNTRRKSTDSV----PISKSTLSRSLSLQA------ 169
Query: 299 RTDKDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTS-RRSEDLDNATEVN 357
D G S G+P V D G + S K + S ++ + TE
Sbjct: 170 ---SDFDGASSSGNPEAVALAPDAYSTGSSSASSTLKRTKKPRPPSLKKKQTTKKPTETP 226
Query: 358 P 358
P
Sbjct: 227 P 227
>gi|115334679 retinoblastoma-binding protein 1 isoform III [Homo
sapiens]
Length = 1188
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/431 (18%), Positives = 172/431 (39%), Gaps = 43/431 (9%)
Query: 205 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 259
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 260 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKV 316
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGN---- 774
Query: 317 NQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDG-LIK 375
+ +K E+ ++ E K R +KT S ++ +++ G + ++ ++
Sbjct: 775 --KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IKISSFGQNEAGSEPHIEAHSLE 829
Query: 376 VDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDS- 432
+ NKN + +D +K ++KR G I++ G E + Q S
Sbjct: 830 LSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSD 888
Query: 433 LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDK 490
I +N + + + EN + +I +N+ +Q E + + N K+D D
Sbjct: 889 CIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDA 948
Query: 491 LIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLE 548
+ + PE ++ DL +L + + I + +S + ++L+ + P+ L
Sbjct: 949 MPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LP 996
Query: 549 NLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVY 608
+++ N V+ S + D + + E S ++G E S +T
Sbjct: 997 PVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNV 1053
Query: 609 STSDRSVIERD 619
++ S+I ++
Sbjct: 1054 ASGTCSIIVQE 1064
>gi|115334673 retinoblastoma-binding protein 1 isoform II [Homo
sapiens]
Length = 1203
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/431 (18%), Positives = 172/431 (39%), Gaps = 43/431 (9%)
Query: 205 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 259
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 260 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKV 316
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGN---- 774
Query: 317 NQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDG-LIK 375
+ +K E+ ++ E K R +KT S ++ +++ G + ++ ++
Sbjct: 775 --KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IKISSFGQNEAGSEPHIEAHSLE 829
Query: 376 VDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDS- 432
+ NKN + +D +K ++KR G I++ G E + Q S
Sbjct: 830 LSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSD 888
Query: 433 LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDK 490
I +N + + + EN + +I +N+ +Q E + + N K+D D
Sbjct: 889 CIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDA 948
Query: 491 LIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLE 548
+ + PE ++ DL +L + + I + +S + ++L+ + P+ L
Sbjct: 949 MPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LP 996
Query: 549 NLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVY 608
+++ N V+ S + D + + E S ++G E S +T
Sbjct: 997 PVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNV 1053
Query: 609 STSDRSVIERD 619
++ S+I ++
Sbjct: 1054 ASGTCSIIVQE 1064
>gi|115334677 retinoblastoma-binding protein 1 isoform I [Homo
sapiens]
Length = 1257
Score = 40.8 bits (94), Expect = 0.004
Identities = 78/431 (18%), Positives = 172/431 (39%), Gaps = 43/431 (9%)
Query: 205 RQDNRQIHPPKPGVYTET-----NRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIK 259
RQ +++ PP + +++A +S + + +L+++ EEL +
Sbjct: 661 RQKSKRGRPPLKSTLSSNMPYGLSKTANSEGKSDSCSSDSETEDALEKNLINEELSLKDE 720
Query: 260 MNKSLNRNQGLDSLFRANPKVEE---REKRAKSLESLIYMSTRTDKDGKGIQSLGSPIKV 316
+ K+ N N D L NPK+ +E ++ L + ++ + +Q G+
Sbjct: 721 LEKNENLND--DKLDEENPKISAHILKENDRTQMQPLETLKLEVGENEQIVQIFGN---- 774
Query: 317 NQRTDKNEKGRQNLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDG-LIK 375
+ +K E+ ++ E K R +KT S ++ +++ G + ++ ++
Sbjct: 775 --KMEKTEEVKKEAEKSPKGKGRRSKTKDLSLEI---IKISSFGQNEAGSEPHIEAHSLE 829
Query: 376 VDPETNKNITRG--QSLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDS- 432
+ NKN + +D +K ++KR G I++ G E + Q S
Sbjct: 830 LSSLDNKNFSSATEDEIDQCVK-EKKLKRKILGQSSPEKKIRIENGMEMTNTVSQERTSD 888
Query: 433 LIKVTPERNRTNQGNQDLEN--LIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDK 490
I +N + + + EN + +I +N+ +Q E + + N K+D D
Sbjct: 889 CIGSEGMKNLNFEQHFERENEGMPSLIAESNQCIQQLTSERFDSPAEETVNIPLKEDEDA 948
Query: 491 LIKVNPEIFTNNQRNQDLANLIKVNPAVIRN--NQSQDLDNLIKVKPSALRNTNRDQNLE 548
+ + PE ++ DL +L + + I + +S + ++L+ + P+ L
Sbjct: 949 MPLIGPETLVCHE--VDLDDLDEKDKTSIEDVAVESSESNSLVSIPPA----------LP 996
Query: 549 NLIEVNSHVSENKNGSSNTGAKQAGPQDTVVYTRTYVENSKSPKDGYQENISGKYIQTVY 608
+++ N V+ S + D + + E S ++G E S +T
Sbjct: 997 PVVQHNFSVASPLTLSQDESRSVKSESDITIEVDSIAEES---QEGLCERESANGFETNV 1053
Query: 609 STSDRSVIERD 619
++ S+I ++
Sbjct: 1054 ASGTCSIIVQE 1064
>gi|55770895 ERBB2 interacting protein isoform 7 [Homo sapiens]
Length = 1302
Score = 40.0 bits (92), Expect = 0.007
Identities = 98/503 (19%), Positives = 188/503 (37%), Gaps = 64/503 (12%)
Query: 100 DRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKK 159
+ D K N DN+L N S + ++T + + + T + T
Sbjct: 363 EMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVL 422
Query: 160 RQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVY 219
FP P + + P + K + V+ +D R+ PP+ G
Sbjct: 423 TNYMFPQQPRTEDVMFISDNESFNPSLWEE-QRKQRAQVAFECDEDKDEREA-PPREG-- 478
Query: 220 TETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMN-------KSLNRNQGL-- 270
N +L N+VK ++ K EE + + + +N++ G+
Sbjct: 479 ---NLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKT 535
Query: 271 -DSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQ 328
+S KV+EREK +I S + + + S GS P+ N + +N K
Sbjct: 536 SESTTTVKSKVDEREKY------MIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIV 589
Query: 329 NLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQ 388
N + V + + ++ S++ E+ P E + + + L + K
Sbjct: 590 NHDDVFEESEELS-----SDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKET---D 641
Query: 389 SLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQ--SLDSLIKVT--PERNRTN 444
SL + + SNQ + + ++ ++ +T+ Q SL S +K T ++
Sbjct: 642 SLSDEV-----THNSNQNNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIR 696
Query: 445 QGNQDLENLIKVIPSANKSSEQ-----------------GLDEHINVSPKAVKNTDGKQD 487
Q +++ +L++ N S+E+ ++E + + K+V +T D
Sbjct: 697 QEDENFNSLLQNGDILNSSTEEKFKAHDKKDFNLPEYDLNVEERLVLIEKSVDSTATADD 756
Query: 488 LDKLIKVNP---EIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRD 544
KL +N ++ TN+ ++ K V+ + L K + L N N+
Sbjct: 757 THKLDHINMNLNKLITNDTFQPEIMERSKTQDIVLGTSF---LSINSKEETEHLENGNKY 813
Query: 545 QNLENLIEVNSHVSENKNGSSNT 567
NLE++ +VN H E + T
Sbjct: 814 PNLESVNKVNGHSEETSQSPNRT 836
>gi|8923909 ERBB2 interacting protein isoform 2 [Homo sapiens]
Length = 1371
Score = 40.0 bits (92), Expect = 0.007
Identities = 98/503 (19%), Positives = 188/503 (37%), Gaps = 64/503 (12%)
Query: 100 DRNDAAKTYKANTLDNQLTNRSMSMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKK 159
+ D K N DN+L N S + ++T + + + T + T
Sbjct: 363 EMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPLIPLQKETDSETQKMVL 422
Query: 160 RQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVY 219
FP P + + P + K + V+ +D R+ PP+ G
Sbjct: 423 TNYMFPQQPRTEDVMFISDNESFNPSLWEE-QRKQRAQVAFECDEDKDEREA-PPREG-- 478
Query: 220 TETNRSAERNIRSQDLDNIVKVATSLQRSDKGEELDNLIKMN-------KSLNRNQGL-- 270
N +L N+VK ++ K EE + + + +N++ G+
Sbjct: 479 ---NLKRYPTPYPDELKNMVKTVQTIVHRLKDEETNEDSGRDLKPHEDQQDINKDVGVKT 535
Query: 271 -DSLFRANPKVEEREKRAKSLESLIYMSTRTDKDGKGIQSLGS-PIKVNQRTDKNEKGRQ 328
+S KV+EREK +I S + + + S GS P+ N + +N K
Sbjct: 536 SESTTTVKSKVDEREKY------MIGNSVQKISEPEAEISPGSLPVTANMKASENLKHIV 589
Query: 329 NLESVAKVNARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLDGLIKVDPETNKNITRGQ 388
N + V + + ++ S++ E+ P E + + + L + K
Sbjct: 590 NHDDVFEESEELS-----SDEEMKMAEMRPPLIETSINQPKVVALSNNKKDDTKET---D 641
Query: 389 SLDNLIKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQ--SLDSLIKVT--PERNRTN 444
SL + + SNQ + + ++ ++ +T+ Q SL S +K T ++
Sbjct: 642 SLSDEV-----THNSNQNNSNCSSPSRMSDSVSLNTDSSQDTSLCSPVKQTHIDINSKIR 696
Query: 445 QGNQDLENLIKVIPSANKSSEQ-----------------GLDEHINVSPKAVKNTDGKQD 487
Q +++ +L++ N S+E+ ++E + + K+V +T D
Sbjct: 697 QEDENFNSLLQNGDILNSSTEEKFKAHDKKDFNLPEYDLNVEERLVLIEKSVDSTATADD 756
Query: 488 LDKLIKVNP---EIFTNNQRNQDLANLIKVNPAVIRNNQSQDLDNLIKVKPSALRNTNRD 544
KL +N ++ TN+ ++ K V+ + L K + L N N+
Sbjct: 757 THKLDHINMNLNKLITNDTFQPEIMERSKTQDIVLGTSF---LSINSKEETEHLENGNKY 813
Query: 545 QNLENLIEVNSHVSENKNGSSNT 567
NLE++ +VN H E + T
Sbjct: 814 PNLESVNKVNGHSEETSQSPNRT 836
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapiens]
Length = 1341
Score = 39.7 bits (91), Expect = 0.009
Identities = 44/215 (20%), Positives = 80/215 (37%), Gaps = 37/215 (17%)
Query: 179 TRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNI 238
T+ E G+ P+ P P PV P R + R+ + E R ER R+
Sbjct: 1106 TKTEEQGIPRPLHPPPPPPVQPPQHPRAEQREQERAVREQWAEREREMERRERT------ 1159
Query: 239 VKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLES------ 292
RS++ + D + + +S +R++ RA K ++ EK+ K+ E
Sbjct: 1160 --------RSEREWDRDKVREGPRSRSRSRDRRRKERAKSKEKKSEKKEKAQEEPPAKLL 1211
Query: 293 -----------LIYMSTRTD-----KDGKGIQSLGSPIKVNQRTDKNEKGRQNLESVAKV 336
IY TD K+ + + K + ++ E+ + E+ +
Sbjct: 1212 DDLFRKTKAAPCIYWLPLTDSQIVQKEAERAERAKEREKRRKEQEEEEQKEREKEAERER 1271
Query: 337 NARMNKTSRRSEDLDNATEVNPKGHENTTGKKDLD 371
N ++ + RR + E + E G +D D
Sbjct: 1272 NRQLEREKRREHSRERDRE-RERERERDRGDRDRD 1305
>gi|239757861 PREDICTED: similar to armadillo repeat containing,
X-linked 4 [Homo sapiens]
Length = 2382
Score = 39.7 bits (91), Expect = 0.009
Identities = 110/562 (19%), Positives = 188/562 (33%), Gaps = 74/562 (13%)
Query: 73 DRKVNERDVP--------KATISRYSSDDTLDRISDRNDAAKTYKANTLD--NQLTNRSM 122
D KV R P KA + S + L D++ A D + L+
Sbjct: 507 DAKVKNRGNPNAMTKAGAKANLRANSQVEALPDARDKSRGNPNVMAKVGDGTDMLSCTQP 566
Query: 123 SMFRSLEVTKLQPGGSLNANTSNTIASTSATTPVKKK----RQSWFPPPPPGYNASSSTG 178
+ S++ L G NT+ A +K + Q P G +
Sbjct: 567 QLVASVQADTLSDGKIKVRGNVNTMPKEGAGVDMKAQGMAQSQGEALPNTRGKARGKAKA 626
Query: 179 TRRREPGVHPPIPPKPSSPVSSPNQLRQDNRQIHPPKPGVYTETNRSAERNIRSQDLDNI 238
+ PG+ +P + V +P + D+R P ++ A++ + Q L
Sbjct: 627 KCKTGPGMDMKTCTQPQAGVKTPAEALLDSRVDGRGNPNATSKAGTKADQRVCGQPL--- 683
Query: 239 VKVATSLQRSDKGEELD---NLIKMNKS--LNRNQGLDSLFRANPKVEEREKRAKSLESL 293
+ + +GE L N +K N L G + A P+ S +
Sbjct: 684 ------VVANPQGEALPGAKNKVKGNPHTVLKVGAGEGTTDSAQPEA------VVSFQGE 731
Query: 294 IYMSTRTDKDG------KGIQSLGSPIKVNQRTDKNEKGRQNLESVAKVNARMNKTSRRS 347
+ T+ G K G+ + + KG L+S KV N S+
Sbjct: 732 ALLGTKNKVKGNPNVVLKAEVGEGAMGTAQLQIMASSKGEALLDSKNKVKGNSNAVSKAG 791
Query: 348 EDLDNATEVNPKGHENTTGK--KDLDGLIKVDPETNKNITRGQSLDNLIKVTPEVKRSNQ 405
D V P+ N+ G+ I+ +P T N G + P+ ++Q
Sbjct: 792 AGTDTTGSVQPQIVANSQGEVLPGAKNKIRGNPTTVPNSGVGPYTTD--SARPQAVANSQ 849
Query: 406 GS--KDLNNFIKVYPGTEKSTEGGQSLDSLIKVTPERNRTNQGNQDLENLIKVIPSANKS 463
G N +K E G ++ N + +N ++ +A
Sbjct: 850 GEVLPGAKNKVKANLNAVSKAEAGMGATGSVQPQAVANSHCETLPGAKNKVRGNWNAVSK 909
Query: 464 SEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNPEIFTNNQRNQDLANLIKVNPAVIRNNQ 523
+ G+D + P+AV N+ G +V P N +K NP V+
Sbjct: 910 AGAGMDTRGSAQPQAVANSQG--------EVLP----------GAKNKVKGNPNVVSKAG 951
Query: 524 SQDLDNLIKVKPSALRNTNRDQNLENLIEVNSHVSENKNGSSNTGAKQ-----AGPQDTV 578
+++ D + +P L ++ R E L + V N N S GA++ A PQ
Sbjct: 952 ARE-DTVGSTQPQVLASSQR----ETLPGARNKVKGNSNVVSKAGAREDTMGSAQPQVVA 1006
Query: 579 VYTRTYVENSKSPKDGYQENIS 600
R + +++ G IS
Sbjct: 1007 NSQRETLPGARNKVKGNSNAIS 1028
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 39.7 bits (91), Expect = 0.009
Identities = 25/92 (27%), Positives = 41/92 (44%), Gaps = 6/92 (6%)
Query: 150 TSATTPVKKKRQSWFPPPPPGYNASSSTGTRRREPGVHPPIPPKPSSPVSSPNQLRQDNR 209
+S P K++ +F PPPP SS + ++ GV + S+PV P +QD +
Sbjct: 1131 SSMADPFKRRGYWYFMPPPPSSKVSSHSSQATKDSGV--GLKYSASTPVRKPRPGQQDGK 1188
Query: 210 QIHPPKPG----VYTETNRSAERNIRSQDLDN 237
+ P P VY+ + S+D D+
Sbjct: 1189 EGSQPPPASGYWVYSPIRSGLHKLFPSRDADS 1220
>gi|224809478 retinoic acid induced 14 isoform d [Homo sapiens]
Length = 983
Score = 39.3 bits (90), Expect = 0.012
Identities = 100/506 (19%), Positives = 202/506 (39%), Gaps = 77/506 (15%)
Query: 125 FRSLEVTKLQPGGSLNANTSNTIASTS-ATTPVKKKRQSWFPPPPPGYNASSSTGTRRRE 183
+ +L +KL + + + I+ + TP K K+ +S +GT ++
Sbjct: 222 YNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKI-----SSERSGTPKKR 276
Query: 184 PGVHPPIPPKPSSPVSSPNQLR----QDNRQIHPPKPGVYTETNRSAERNIRSQD----L 235
PPI P S VSSP + + +P E + E R D
Sbjct: 277 KAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 336
Query: 236 DNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIY 295
D+++ +++ + D L + + +L+ + D L +PK E + S Y
Sbjct: 337 DSLLDISSEADQQDLLSLLQAKV-ASLTLHNKELQDKLQAKSPKEAEADLSFDS-----Y 390
Query: 296 MSTRTD-------------KDGKG-----IQSLG-----SPIKVNQRTDKNEKGRQNLES 332
ST+TD D K I SLG + +++ Q + + ++ LES
Sbjct: 391 HSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLES 450
Query: 333 --VAKVNARMNKTSRRSEDL--------DNATEVNPKGHENTTGKKD-LDGLIKVDPETN 381
+ ++ SRR+E + +N+++++ K E + ++ + ++ V +
Sbjct: 451 SEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 510
Query: 382 KNITRGQSLDNL-----IKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKV 436
+ +S+DN ++VT E N +DL N + E+S + + L +
Sbjct: 511 LGLVSPESMDNYSHFHELRVTEE--EINVLKQDLQNAL------EESERNKEKVRELEEK 562
Query: 437 TPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNP 496
ER + +E ++ KSS + E++N KA ++ ++++K+
Sbjct: 563 LVEREKGTVIKPPVEEYEEM-----KSSYCSVIENMN-KEKAFLFEKYQEAQEEIMKLKD 616
Query: 497 EIFTN-NQRNQDLANLIK--VNPAVIR-NNQSQDLDNLIKVKPSALRNTNRDQNLENLIE 552
+ + Q D A +K +N + N Q +L L K + L + + ++LE++
Sbjct: 617 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 676
Query: 553 VNSHVSENKNGSSNTGAKQAGPQDTV 578
H +E++ T +A +D +
Sbjct: 677 EYIHKAEHEKLMQLTNVSRAKAEDAL 702
>gi|224809476 retinoic acid induced 14 isoform c [Homo sapiens]
Length = 972
Score = 39.3 bits (90), Expect = 0.012
Identities = 100/506 (19%), Positives = 202/506 (39%), Gaps = 77/506 (15%)
Query: 125 FRSLEVTKLQPGGSLNANTSNTIASTS-ATTPVKKKRQSWFPPPPPGYNASSSTGTRRRE 183
+ +L +KL + + + I+ + TP K K+ +S +GT ++
Sbjct: 211 YNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKI-----SSERSGTPKKR 265
Query: 184 PGVHPPIPPKPSSPVSSPNQLR----QDNRQIHPPKPGVYTETNRSAERNIRSQD----L 235
PPI P S VSSP + + +P E + E R D
Sbjct: 266 KAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 325
Query: 236 DNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIY 295
D+++ +++ + D L + + +L+ + D L +PK E + S Y
Sbjct: 326 DSLLDISSEADQQDLLSLLQAKV-ASLTLHNKELQDKLQAKSPKEAEADLSFDS-----Y 379
Query: 296 MSTRTD-------------KDGKG-----IQSLG-----SPIKVNQRTDKNEKGRQNLES 332
ST+TD D K I SLG + +++ Q + + ++ LES
Sbjct: 380 HSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLES 439
Query: 333 --VAKVNARMNKTSRRSEDL--------DNATEVNPKGHENTTGKKD-LDGLIKVDPETN 381
+ ++ SRR+E + +N+++++ K E + ++ + ++ V +
Sbjct: 440 SEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 499
Query: 382 KNITRGQSLDNL-----IKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKV 436
+ +S+DN ++VT E N +DL N + E+S + + L +
Sbjct: 500 LGLVSPESMDNYSHFHELRVTEE--EINVLKQDLQNAL------EESERNKEKVRELEEK 551
Query: 437 TPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNP 496
ER + +E ++ KSS + E++N KA ++ ++++K+
Sbjct: 552 LVEREKGTVIKPPVEEYEEM-----KSSYCSVIENMN-KEKAFLFEKYQEAQEEIMKLKD 605
Query: 497 EIFTN-NQRNQDLANLIK--VNPAVIR-NNQSQDLDNLIKVKPSALRNTNRDQNLENLIE 552
+ + Q D A +K +N + N Q +L L K + L + + ++LE++
Sbjct: 606 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 665
Query: 553 VNSHVSENKNGSSNTGAKQAGPQDTV 578
H +E++ T +A +D +
Sbjct: 666 EYIHKAEHEKLMQLTNVSRAKAEDAL 691
>gi|224809472 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 39.3 bits (90), Expect = 0.012
Identities = 100/506 (19%), Positives = 202/506 (39%), Gaps = 77/506 (15%)
Query: 125 FRSLEVTKLQPGGSLNANTSNTIASTS-ATTPVKKKRQSWFPPPPPGYNASSSTGTRRRE 183
+ +L +KL + + + I+ + TP K K+ +S +GT ++
Sbjct: 219 YNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKI-----SSERSGTPKKR 273
Query: 184 PGVHPPIPPKPSSPVSSPNQLR----QDNRQIHPPKPGVYTETNRSAERNIRSQD----L 235
PPI P S VSSP + + +P E + E R D
Sbjct: 274 KAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 333
Query: 236 DNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIY 295
D+++ +++ + D L + + +L+ + D L +PK E + S Y
Sbjct: 334 DSLLDISSEADQQDLLSLLQAKV-ASLTLHNKELQDKLQAKSPKEAEADLSFDS-----Y 387
Query: 296 MSTRTD-------------KDGKG-----IQSLG-----SPIKVNQRTDKNEKGRQNLES 332
ST+TD D K I SLG + +++ Q + + ++ LES
Sbjct: 388 HSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLES 447
Query: 333 --VAKVNARMNKTSRRSEDL--------DNATEVNPKGHENTTGKKD-LDGLIKVDPETN 381
+ ++ SRR+E + +N+++++ K E + ++ + ++ V +
Sbjct: 448 SEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 507
Query: 382 KNITRGQSLDNL-----IKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKV 436
+ +S+DN ++VT E N +DL N + E+S + + L +
Sbjct: 508 LGLVSPESMDNYSHFHELRVTEE--EINVLKQDLQNAL------EESERNKEKVRELEEK 559
Query: 437 TPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNP 496
ER + +E ++ KSS + E++N KA ++ ++++K+
Sbjct: 560 LVEREKGTVIKPPVEEYEEM-----KSSYCSVIENMN-KEKAFLFEKYQEAQEEIMKLKD 613
Query: 497 EIFTN-NQRNQDLANLIK--VNPAVIR-NNQSQDLDNLIKVKPSALRNTNRDQNLENLIE 552
+ + Q D A +K +N + N Q +L L K + L + + ++LE++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 553 VNSHVSENKNGSSNTGAKQAGPQDTV 578
H +E++ T +A +D +
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDAL 699
>gi|224809470 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 39.3 bits (90), Expect = 0.012
Identities = 100/506 (19%), Positives = 202/506 (39%), Gaps = 77/506 (15%)
Query: 125 FRSLEVTKLQPGGSLNANTSNTIASTS-ATTPVKKKRQSWFPPPPPGYNASSSTGTRRRE 183
+ +L +KL + + + I+ + TP K K+ +S +GT ++
Sbjct: 219 YNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKI-----SSERSGTPKKR 273
Query: 184 PGVHPPIPPKPSSPVSSPNQLR----QDNRQIHPPKPGVYTETNRSAERNIRSQD----L 235
PPI P S VSSP + + +P E + E R D
Sbjct: 274 KAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 333
Query: 236 DNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIY 295
D+++ +++ + D L + + +L+ + D L +PK E + S Y
Sbjct: 334 DSLLDISSEADQQDLLSLLQAKV-ASLTLHNKELQDKLQAKSPKEAEADLSFDS-----Y 387
Query: 296 MSTRTD-------------KDGKG-----IQSLG-----SPIKVNQRTDKNEKGRQNLES 332
ST+TD D K I SLG + +++ Q + + ++ LES
Sbjct: 388 HSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLES 447
Query: 333 --VAKVNARMNKTSRRSEDL--------DNATEVNPKGHENTTGKKD-LDGLIKVDPETN 381
+ ++ SRR+E + +N+++++ K E + ++ + ++ V +
Sbjct: 448 SEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 507
Query: 382 KNITRGQSLDNL-----IKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKV 436
+ +S+DN ++VT E N +DL N + E+S + + L +
Sbjct: 508 LGLVSPESMDNYSHFHELRVTEE--EINVLKQDLQNAL------EESERNKEKVRELEEK 559
Query: 437 TPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNP 496
ER + +E ++ KSS + E++N KA ++ ++++K+
Sbjct: 560 LVEREKGTVIKPPVEEYEEM-----KSSYCSVIENMN-KEKAFLFEKYQEAQEEIMKLKD 613
Query: 497 EIFTN-NQRNQDLANLIK--VNPAVIR-NNQSQDLDNLIKVKPSALRNTNRDQNLENLIE 552
+ + Q D A +K +N + N Q +L L K + L + + ++LE++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 553 VNSHVSENKNGSSNTGAKQAGPQDTV 578
H +E++ T +A +D +
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDAL 699
>gi|224809468 retinoic acid induced 14 isoform a [Homo sapiens]
Length = 980
Score = 39.3 bits (90), Expect = 0.012
Identities = 100/506 (19%), Positives = 202/506 (39%), Gaps = 77/506 (15%)
Query: 125 FRSLEVTKLQPGGSLNANTSNTIASTS-ATTPVKKKRQSWFPPPPPGYNASSSTGTRRRE 183
+ +L +KL + + + I+ + TP K K+ +S +GT ++
Sbjct: 219 YNALHYSKLSENAGIQSLLLSKISQDADLKTPTKPKQHDQVSKI-----SSERSGTPKKR 273
Query: 184 PGVHPPIPPKPSSPVSSPNQLR----QDNRQIHPPKPGVYTETNRSAERNIRSQD----L 235
PPI P S VSSP + + +P E + E R D
Sbjct: 274 KAPPPPISPTQLSDVSSPRSITSTPLSGKESVFFAEPPFKAEISSIRENKDRLSDSTTGA 333
Query: 236 DNIVKVATSLQRSDKGEELDNLIKMNKSLNRNQGLDSLFRANPKVEEREKRAKSLESLIY 295
D+++ +++ + D L + + +L+ + D L +PK E + S Y
Sbjct: 334 DSLLDISSEADQQDLLSLLQAKV-ASLTLHNKELQDKLQAKSPKEAEADLSFDS-----Y 387
Query: 296 MSTRTD-------------KDGKG-----IQSLG-----SPIKVNQRTDKNEKGRQNLES 332
ST+TD D K I SLG + +++ Q + + ++ LES
Sbjct: 388 HSTQTDLGPSLGKPGETSPPDSKSSPSVLIHSLGKSTTDNDVRIQQLQEILQDLQKRLES 447
Query: 333 --VAKVNARMNKTSRRSEDL--------DNATEVNPKGHENTTGKKD-LDGLIKVDPETN 381
+ ++ SRR+E + +N+++++ K E + ++ + ++ V +
Sbjct: 448 SEAERKQLQVELQSRRAELVCLNNTEISENSSDLSQKLKETQSKYEEAMKEVLSVQKQMK 507
Query: 382 KNITRGQSLDNL-----IKVTPEVKRSNQGSKDLNNFIKVYPGTEKSTEGGQSLDSLIKV 436
+ +S+DN ++VT E N +DL N + E+S + + L +
Sbjct: 508 LGLVSPESMDNYSHFHELRVTEE--EINVLKQDLQNAL------EESERNKEKVRELEEK 559
Query: 437 TPERNRTNQGNQDLENLIKVIPSANKSSEQGLDEHINVSPKAVKNTDGKQDLDKLIKVNP 496
ER + +E ++ KSS + E++N KA ++ ++++K+
Sbjct: 560 LVEREKGTVIKPPVEEYEEM-----KSSYCSVIENMN-KEKAFLFEKYQEAQEEIMKLKD 613
Query: 497 EIFTN-NQRNQDLANLIK--VNPAVIR-NNQSQDLDNLIKVKPSALRNTNRDQNLENLIE 552
+ + Q D A +K +N + N Q +L L K + L + + ++LE++
Sbjct: 614 TLKSQMTQEASDEAEDMKEAMNRMIDELNKQVSELSQLYKEAQAELEDYRKRKSLEDVTA 673
Query: 553 VNSHVSENKNGSSNTGAKQAGPQDTV 578
H +E++ T +A +D +
Sbjct: 674 EYIHKAEHEKLMQLTNVSRAKAEDAL 699
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.126 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,656,767
Number of Sequences: 37866
Number of extensions: 1412785
Number of successful extensions: 8243
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 50
Number of HSP's successfully gapped in prelim test: 365
Number of HSP's that attempted gapping in prelim test: 7033
Number of HSP's gapped (non-prelim): 1197
length of query: 688
length of database: 18,247,518
effective HSP length: 109
effective length of query: 579
effective length of database: 14,120,124
effective search space: 8175551796
effective search space used: 8175551796
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.