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Search of human proteins with 237820620
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237820620 glutamate-rich WD repeat containing 1 [Homo
sapiens]
(446 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens] 922 0.0
gi|207029439 retinoblastoma binding protein 4 isoform c [Homo sa... 124 1e-28
gi|207029415 retinoblastoma binding protein 4 isoform b [Homo sa... 124 1e-28
gi|5032027 retinoblastoma binding protein 4 isoform a [Homo sapi... 124 1e-28
gi|4506439 retinoblastoma binding protein 7 [Homo sapiens] 123 4e-28
gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens] 79 6e-15
gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens] 76 5e-14
gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens] 76 5e-14
gi|58331266 WD repeat domain 59 [Homo sapiens] 73 5e-13
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 71 2e-12
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 68 2e-11
gi|16554629 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|16554627 WD repeat domain 5 [Homo sapiens] 67 3e-11
gi|62234438 Notchless gene homolog isoform b [Homo sapiens] 67 3e-11
gi|62234461 Notchless gene homolog isoform a [Homo sapiens] 67 3e-11
gi|83779014 katanin p80 subunit B 1 [Homo sapiens] 67 4e-11
gi|14149987 WD repeat domain 24 [Homo sapiens] 66 6e-11
gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens] 66 7e-11
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 65 1e-10
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 65 1e-10
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 65 1e-10
gi|4757988 WD repeat domain 39 [Homo sapiens] 65 1e-10
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 64 2e-10
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 64 2e-10
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 64 2e-10
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 64 2e-10
gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)... 64 4e-10
gi|217330644 WD repeat domain 12 protein [Homo sapiens] 63 5e-10
gi|21071067 TBP-associated factor 5 [Homo sapiens] 63 6e-10
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 63 6e-10
>gi|237820620 glutamate-rich WD repeat containing 1 [Homo sapiens]
Length = 446
Score = 922 bits (2382), Expect = 0.0
Identities = 446/446 (100%), Positives = 446/446 (100%)
Query: 1 MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA 60
MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA
Sbjct: 1 MAARKGRRRTCETGEPMEAESGDTSSEGPAQVYLPGRGPPLREGEELVMDEEAYVLYHRA 60
Query: 61 QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE 120
QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE
Sbjct: 61 QTGAPCLSFDIVRDHLGDNRTELPLTLYLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSE 120
Query: 121 GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL 180
GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL
Sbjct: 121 GSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFAL 180
Query: 181 RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH 240
RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH
Sbjct: 181 RRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIH 240
Query: 241 LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM 300
LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM
Sbjct: 241 LWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACM 300
Query: 301 LTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE 360
LTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE
Sbjct: 301 LTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVE 360
Query: 361 WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL 420
WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL
Sbjct: 361 WHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKEL 420
Query: 421 HWHPQCPGLLVSTALSGFTIFRTISV 446
HWHPQCPGLLVSTALSGFTIFRTISV
Sbjct: 421 HWHPQCPGLLVSTALSGFTIFRTISV 446
>gi|207029439 retinoblastoma binding protein 4 isoform c [Homo
sapiens]
Length = 390
Score = 124 bits (312), Expect = 1e-28
Identities = 73/243 (30%), Positives = 122/243 (50%), Gaps = 17/243 (6%)
Query: 199 DEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW----TPTDGGSWHVDQ 254
D + P GH EG+ L W+P ++G LL+ I LW P +G VD
Sbjct: 127 DPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKV--VDA 184
Query: 255 RP-FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+ F GHT VED+ W ++F S + D + IWD R + + + + AH +VN
Sbjct: 185 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR-SNNTSKPSHSVDAHTAEVNC 243
Query: 314 ISWSRREPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
+S++ F+L +G D + +WDLR K + +F+ H + V+W P + + A+S
Sbjct: 244 LSFNPYSEFILATGSADKTVALWDLRNLK--LKLHSFESHKDEIFQVQWSPHNETILASS 301
Query: 373 GADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGET-ELKELHWHPQCPGLLV 431
G D ++ WDL+ + G+ ++ D P +LLF+H G T ++ + W+P P ++
Sbjct: 302 GTDRRLNVWDLS-----KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVIC 356
Query: 432 STA 434
S +
Sbjct: 357 SVS 359
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 16/98 (16%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRP---------- 256
+ SF H E F + WSP L + + +++W + G +Q P
Sbjct: 275 LHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE---EQSPEDAEDGPPEL 331
Query: 257 -FV--GHTRSVEDLQWSPTENTVFASCSADASIRIWDI 291
F+ GHT + D W+P E V S S D +++W +
Sbjct: 332 LFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 369
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 11/136 (8%)
Query: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTAT------AHDGDV 311
+ H V ++ P + A+ + + + ++D PSK H +
Sbjct: 86 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 145
Query: 312 NVISWS-RREPFLLSGGDDGALKIWDLRQF-KSGSPV---ATFKQHVAPVTSVEWHPQDS 366
+SW+ LLS DD + +WD+ K G V F H A V V WH
Sbjct: 146 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 205
Query: 367 GVFAASGADHQITQWD 382
+F + D ++ WD
Sbjct: 206 SLFGSVADDQKLMIWD 221
>gi|207029415 retinoblastoma binding protein 4 isoform b [Homo
sapiens]
Length = 424
Score = 124 bits (312), Expect = 1e-28
Identities = 73/243 (30%), Positives = 122/243 (50%), Gaps = 17/243 (6%)
Query: 199 DEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW----TPTDGGSWHVDQ 254
D + P GH EG+ L W+P ++G LL+ I LW P +G VD
Sbjct: 161 DPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKV--VDA 218
Query: 255 RP-FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+ F GHT VED+ W ++F S + D + IWD R + + + + AH +VN
Sbjct: 219 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR-SNNTSKPSHSVDAHTAEVNC 277
Query: 314 ISWSRREPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
+S++ F+L +G D + +WDLR K + +F+ H + V+W P + + A+S
Sbjct: 278 LSFNPYSEFILATGSADKTVALWDLRNLK--LKLHSFESHKDEIFQVQWSPHNETILASS 335
Query: 373 GADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGET-ELKELHWHPQCPGLLV 431
G D ++ WDL+ + G+ ++ D P +LLF+H G T ++ + W+P P ++
Sbjct: 336 GTDRRLNVWDLS-----KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVIC 390
Query: 432 STA 434
S +
Sbjct: 391 SVS 393
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 16/98 (16%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRP---------- 256
+ SF H E F + WSP L + + +++W + G +Q P
Sbjct: 309 LHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE---EQSPEDAEDGPPEL 365
Query: 257 -FV--GHTRSVEDLQWSPTENTVFASCSADASIRIWDI 291
F+ GHT + D W+P E V S S D +++W +
Sbjct: 366 LFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 403
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 11/136 (8%)
Query: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTAT------AHDGDV 311
+ H V ++ P + A+ + + + ++D PSK H +
Sbjct: 120 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 179
Query: 312 NVISWS-RREPFLLSGGDDGALKIWDLRQF-KSGSPV---ATFKQHVAPVTSVEWHPQDS 366
+SW+ LLS DD + +WD+ K G V F H A V V WH
Sbjct: 180 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 239
Query: 367 GVFAASGADHQITQWD 382
+F + D ++ WD
Sbjct: 240 SLFGSVADDQKLMIWD 255
>gi|5032027 retinoblastoma binding protein 4 isoform a [Homo
sapiens]
Length = 425
Score = 124 bits (312), Expect = 1e-28
Identities = 73/243 (30%), Positives = 122/243 (50%), Gaps = 17/243 (6%)
Query: 199 DEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLW----TPTDGGSWHVDQ 254
D + P GH EG+ L W+P ++G LL+ I LW P +G VD
Sbjct: 162 DPSGECNPDLRLRGHQKEGYGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKV--VDA 219
Query: 255 RP-FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+ F GHT VED+ W ++F S + D + IWD R + + + + AH +VN
Sbjct: 220 KTIFTGHTAVVEDVSWHLLHESLFGSVADDQKLMIWDTR-SNNTSKPSHSVDAHTAEVNC 278
Query: 314 ISWSRREPFLL-SGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
+S++ F+L +G D + +WDLR K + +F+ H + V+W P + + A+S
Sbjct: 279 LSFNPYSEFILATGSADKTVALWDLRNLK--LKLHSFESHKDEIFQVQWSPHNETILASS 336
Query: 373 GADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGET-ELKELHWHPQCPGLLV 431
G D ++ WDL+ + G+ ++ D P +LLF+H G T ++ + W+P P ++
Sbjct: 337 GTDRRLNVWDLS-----KIGEEQSPEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVIC 391
Query: 432 STA 434
S +
Sbjct: 392 SVS 394
Score = 43.9 bits (102), Expect = 3e-04
Identities = 26/98 (26%), Positives = 42/98 (42%), Gaps = 16/98 (16%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRP---------- 256
+ SF H E F + WSP L + + +++W + G +Q P
Sbjct: 310 LHSFESHKDEIFQVQWSPHNETILASSGTDRRLNVWDLSKIGE---EQSPEDAEDGPPEL 366
Query: 257 -FV--GHTRSVEDLQWSPTENTVFASCSADASIRIWDI 291
F+ GHT + D W+P E V S S D +++W +
Sbjct: 367 LFIHGGHTAKISDFSWNPNEPWVICSVSEDNIMQVWQM 404
Score = 42.7 bits (99), Expect = 7e-04
Identities = 32/136 (23%), Positives = 52/136 (38%), Gaps = 11/136 (8%)
Query: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTAT------AHDGDV 311
+ H V ++ P + A+ + + + ++D PSK H +
Sbjct: 121 INHEGEVNRARYMPQNPCIIATKTPSSDVLVFDYTKHPSKPDPSGECNPDLRLRGHQKEG 180
Query: 312 NVISWS-RREPFLLSGGDDGALKIWDLRQF-KSGSPV---ATFKQHVAPVTSVEWHPQDS 366
+SW+ LLS DD + +WD+ K G V F H A V V WH
Sbjct: 181 YGLSWNPNLSGHLLSASDDHTICLWDISAVPKEGKVVDAKTIFTGHTAVVEDVSWHLLHE 240
Query: 367 GVFAASGADHQITQWD 382
+F + D ++ WD
Sbjct: 241 SLFGSVADDQKLMIWD 256
>gi|4506439 retinoblastoma binding protein 7 [Homo sapiens]
Length = 425
Score = 123 bits (308), Expect = 4e-28
Identities = 96/356 (26%), Positives = 160/356 (44%), Gaps = 35/356 (9%)
Query: 88 YLCAGTQAESAQSNRLMMLRMHNLHGTKPPPSEGSDEEEEEEDEEDEEERKPQLELAMVP 147
+L GT Q N L++ R+H + + D ++ E K + E+ +
Sbjct: 64 WLVLGTHTSDEQ-NHLVVARVHIPNDDAQFDASHCDSDKGEFGGFGSVTGKIECEIK-IN 121
Query: 148 HYGGINRVRVSWLGEEP-VAGVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKP 206
H G +NR R ++ + P + + V VF + P D + P
Sbjct: 122 HEGEVNRAR--YMPQNPHIIATKTPSSDVLVF------DYTKHPAK-----PDPSGECNP 168
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWT----PTDGGSWHVDQRP-FVGHT 261
GH EG+ L W+ ++G LL+ + LW P +G VD + F GH+
Sbjct: 169 DLRLRGHQKEGYGLSWNSNLSGHLLSASDDHTVCLWDINAGPKEGKI--VDAKAIFTGHS 226
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRA-APSKACMLTTATAHDGDVNVISWSRRE 320
VED+ W ++F S + D + IWD R+ SK L A H +VN +S++
Sbjct: 227 AVVEDVAWHLLHESLFGSVADDQKLMIWDTRSNTTSKPSHLVDA--HTAEVNCLSFNPYS 284
Query: 321 PFLLSGGD-DGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQIT 379
F+L+ G D + +WDLR K + TF+ H + V W P + + A+SG D ++
Sbjct: 285 EFILATGSADKTVALWDLRNLKL--KLHTFESHKDEIFQVHWSPHNETILASSGTDRRLN 342
Query: 380 QWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGET-ELKELHWHPQCPGLLVSTA 434
WDL+ + G+ ++ D P +LLF+H G T ++ + W+P P ++ S +
Sbjct: 343 VWDLS-----KIGEEQSAEDAEDGPPELLFIHGGHTAKISDFSWNPNEPWVICSVS 393
Score = 41.6 bits (96), Expect = 0.001
Identities = 25/95 (26%), Positives = 40/95 (42%), Gaps = 10/95 (10%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHV-----DQRPFV--- 258
+ +F H E F + WSP L + + +++W + G D P +
Sbjct: 309 LHTFESHKDEIFQVHWSPHNETILASSGTDRRLNVWDLSKIGEEQSAEDAEDGPPELLFI 368
Query: 259 --GHTRSVEDLQWSPTENTVFASCSADASIRIWDI 291
GHT + D W+P E V S S D ++IW +
Sbjct: 369 HGGHTAKISDFSWNPNEPWVICSVSEDNIMQIWQM 403
>gi|4505731 peroxisomal biogenesis factor 7 [Homo sapiens]
Length = 323
Score = 79.3 bits (194), Expect = 6e-15
Identities = 52/181 (28%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 206 PIFSFAGHMGEGFALDWSP-RVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSV 264
P+ + H E +++DWS R +++G + + LW PT G S F GH +
Sbjct: 103 PLQVYKEHAQEVYSVDWSQTRGEQLVVSGSWDQTVKLWDPTVGKSLCT----FRGHESII 158
Query: 265 EDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR-REPFL 323
WSP FAS S D ++RIWD++AA + + AH ++ W + E L
Sbjct: 159 YSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVI----PAHQAEILSCDWCKYNENLL 214
Query: 324 LSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDL 383
++G D +L+ WDLR + PV H + V++ P + V A+ D + W+
Sbjct: 215 VTGAVDCSLRGWDLRNVR--QPVFELLGHTYAIRRVKFSPFHASVLASCSYDFTVRFWNF 272
Query: 384 A 384
+
Sbjct: 273 S 273
Score = 68.2 bits (165), Expect = 1e-11
Identities = 51/176 (28%), Positives = 79/176 (44%), Gaps = 18/176 (10%)
Query: 217 GFALDWSPRVTGRLLTGDCQK-------NIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQW 269
G+A ++SP + GRL Q + + P + G R F + + D+ W
Sbjct: 19 GYAAEFSPYLPGRLACATAQHYGIAGCGTLLILDPDEAGLRLF--RSFDWND-GLFDVTW 75
Query: 270 SPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS--RREPFLLSGG 327
S V +CS D S+++WD A A L H +V + WS R E ++SG
Sbjct: 76 SENNEHVLITCSGDGSLQLWDTAKA---AGPLQVYKEHAQEVYSVDWSQTRGEQLVVSGS 132
Query: 328 DDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDL 383
D +K+WD KS + TF+ H + + S W P G FA++ D + WD+
Sbjct: 133 WDQTVKLWDPTVGKS---LCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDV 185
Score = 54.3 bits (129), Expect = 2e-07
Identities = 44/175 (25%), Positives = 67/175 (38%), Gaps = 14/175 (8%)
Query: 218 FALDWSPRVTGRLLTGDCQKNIHLW-TPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENT- 275
F + WS L+T ++ LW T G V + H + V + WS T
Sbjct: 71 FDVTWSENNEHVLITCSGDGSLQLWDTAKAAGPLQV----YKEHAQEVYSVDWSQTRGEQ 126
Query: 276 VFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP-FLLSGGDDGALKI 334
+ S S D ++++WD P+ L T H+ + WS P S D L+I
Sbjct: 127 LVVSGSWDQTVKLWD----PTVGKSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRI 182
Query: 335 WDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDP 389
WD+ K+ H A + S +W + + D + WDL R P
Sbjct: 183 WDV---KAAGVRIVIPAHQAEILSCDWCKYNENLLVTGAVDCSLRGWDLRNVRQP 234
Score = 38.9 bits (89), Expect = 0.010
Identities = 37/173 (21%), Positives = 65/173 (37%), Gaps = 44/173 (25%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGG---------------S 249
K + +F GH ++ WSP + G + + + +W G
Sbjct: 146 KSLCTFRGHESIIYSTIWSPHIPGCFASASGDQTLRIWDVKAAGVRIVIPAHQAEILSCD 205
Query: 250 W-----------------------HVDQRPF--VGHTRSVEDLQWSPTENTVFASCSADA 284
W +V Q F +GHT ++ +++SP +V ASCS D
Sbjct: 206 WCKYNENLLVTGAVDCSLRGWDLRNVRQPVFELLGHTYAIRRVKFSPFHASVLASCSYDF 265
Query: 285 SIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGD-DGALKIWD 336
++R W+ S +L T H + +S + P ++ D +KI+D
Sbjct: 266 TVRFWNFSKPDS---LLETVEHHTEFTCGLDFSLQSPTQVADCSWDETIKIYD 315
>gi|55743149 WD repeat domain 17 isoform 2 [Homo sapiens]
Length = 1298
Score = 76.3 bits (186), Expect = 5e-14
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 10/186 (5%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H F DWS + TG N+ ++ + + F GHT V ++WSP
Sbjct: 496 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPL--KVFSGHTAKVFHVKWSPL 553
Query: 273 ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLL-SGGDDGA 331
+ S S D ++RIWD AC + H V + W+ P+LL SG D
Sbjct: 554 REGILCSGSDDGTVRIWDY---TQDAC-INILNGHTAPVRGLMWNTEIPYLLISGSWDYT 609
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEA 391
+K+WD R+ G+ V T H A V + HP A+ D + W L P
Sbjct: 610 IKVWDTRE---GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQ 666
Query: 392 GDVEAD 397
++ AD
Sbjct: 667 INILAD 672
Score = 56.2 bits (134), Expect = 6e-08
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 9/134 (6%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSV 264
+P+ F+GH + F + WSP G L +G + +W T ++ GHT V
Sbjct: 533 QPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINI----LNGHTAPV 588
Query: 265 EDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPF-L 323
L W+ + S S D +I++WD R + + T H DV ++ PF +
Sbjct: 589 RGLMWNTEIPYLLISGSWDYTIKVWDTR----EGTCVDTVYDHGADVYGLTCHPSRPFTM 644
Query: 324 LSGGDDGALKIWDL 337
S D +++W L
Sbjct: 645 ASCSRDSTVRLWSL 658
Score = 53.5 bits (127), Expect = 4e-07
Identities = 46/215 (21%), Positives = 78/215 (36%), Gaps = 44/215 (20%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGG----------------SW 250
+++ G+ G ++L W+P + G + +W G +W
Sbjct: 405 VYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAW 464
Query: 251 -HVDQRPFV---------------------GHTRSVEDLQWSPTENTVFASCSADASIRI 288
H D + H +V WS + A+ D ++R+
Sbjct: 465 SHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV 524
Query: 289 WDIRAAPSKACMLTTATAHDGDVNVISWS-RREPFLLSGGDDGALKIWDLRQFKSGSPVA 347
+ + A S L + H V + WS RE L SG DDG ++IWD Q + +
Sbjct: 525 YYV--ATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQ---DACIN 579
Query: 348 TFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWD 382
H APV + W+ + + + D+ I WD
Sbjct: 580 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 614
Score = 45.8 bits (107), Expect = 8e-05
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 11/121 (9%)
Query: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS 317
+GH ++ D ++ P + + A+ S D +I++WDI + + T+ ++G + +SW+
Sbjct: 366 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTA----VYTSPGNEGVIYSLSWA 421
Query: 318 RREPFLLSGGD--DGALKIWDLRQFKSGSPVATFKQH-VAPVTSVEWHPQDSGVFAASGA 374
++GG +GA IW++++ G + F +H + + W +DS A +
Sbjct: 422 PGGLNCIAGGTSRNGAF-IWNVQK---GKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSS 477
Query: 375 D 375
D
Sbjct: 478 D 478
Score = 31.6 bits (70), Expect = 1.5
Identities = 10/41 (24%), Positives = 23/41 (56%)
Query: 347 ATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVER 387
A +H +T++ W P + +FA+ D+ + W++A ++
Sbjct: 53 AIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQK 93
Score = 30.4 bits (67), Expect = 3.4
Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 6/110 (5%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS-R 318
H +++ + W P +FAS S D + IW++ ++ ++ + G +SW
Sbjct: 58 HKKTITAISWCPHNPDLFASGSTDNLVIIWNV----AEQKVIAKLDSTKGIPASLSWCWN 113
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPV-ATFKQHVAPVTSVEWHPQDSG 367
E + G L IW + SG V ++ + WH G
Sbjct: 114 AEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKG 163
>gi|31317311 WD repeat domain 17 isoform 1 [Homo sapiens]
Length = 1322
Score = 76.3 bits (186), Expect = 5e-14
Identities = 53/186 (28%), Positives = 77/186 (41%), Gaps = 10/186 (5%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H F DWS + TG N+ ++ + + F GHT V ++WSP
Sbjct: 520 HPAAVFGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPL--KVFSGHTAKVFHVKWSPL 577
Query: 273 ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLL-SGGDDGA 331
+ S S D ++RIWD AC + H V + W+ P+LL SG D
Sbjct: 578 REGILCSGSDDGTVRIWDY---TQDAC-INILNGHTAPVRGLMWNTEIPYLLISGSWDYT 633
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEA 391
+K+WD R+ G+ V T H A V + HP A+ D + W L P
Sbjct: 634 IKVWDTRE---GTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLTALVTPVQ 690
Query: 392 GDVEAD 397
++ AD
Sbjct: 691 INILAD 696
Score = 56.2 bits (134), Expect = 6e-08
Identities = 36/134 (26%), Positives = 59/134 (44%), Gaps = 9/134 (6%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSV 264
+P+ F+GH + F + WSP G L +G + +W T ++ GHT V
Sbjct: 557 QPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINI----LNGHTAPV 612
Query: 265 EDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPF-L 323
L W+ + S S D +I++WD R + + T H DV ++ PF +
Sbjct: 613 RGLMWNTEIPYLLISGSWDYTIKVWDTR----EGTCVDTVYDHGADVYGLTCHPSRPFTM 668
Query: 324 LSGGDDGALKIWDL 337
S D +++W L
Sbjct: 669 ASCSRDSTVRLWSL 682
Score = 53.5 bits (127), Expect = 4e-07
Identities = 46/215 (21%), Positives = 78/215 (36%), Gaps = 44/215 (20%)
Query: 207 IFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGG----------------SW 250
+++ G+ G ++L W+P + G + +W G +W
Sbjct: 429 VYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRFNEHGTNGIFCIAW 488
Query: 251 -HVDQRPFV---------------------GHTRSVEDLQWSPTENTVFASCSADASIRI 288
H D + H +V WS + A+ D ++R+
Sbjct: 489 SHKDSKRIATCSSDGFCIIRTIDGKVLHKYKHPAAVFGCDWSQNNKDMIATGCEDTNVRV 548
Query: 289 WDIRAAPSKACMLTTATAHDGDVNVISWS-RREPFLLSGGDDGALKIWDLRQFKSGSPVA 347
+ + A S L + H V + WS RE L SG DDG ++IWD Q + +
Sbjct: 549 YYV--ATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDYTQ---DACIN 603
Query: 348 TFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWD 382
H APV + W+ + + + D+ I WD
Sbjct: 604 ILNGHTAPVRGLMWNTEIPYLLISGSWDYTIKVWD 638
Score = 45.8 bits (107), Expect = 8e-05
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 11/121 (9%)
Query: 258 VGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS 317
+GH ++ D ++ P + + A+ S D +I++WDI + + T+ ++G + +SW+
Sbjct: 390 LGHVETIFDCKFKPDDPNLLATASFDGTIKVWDINTLTA----VYTSPGNEGVIYSLSWA 445
Query: 318 RREPFLLSGGD--DGALKIWDLRQFKSGSPVATFKQH-VAPVTSVEWHPQDSGVFAASGA 374
++GG +GA IW++++ G + F +H + + W +DS A +
Sbjct: 446 PGGLNCIAGGTSRNGAF-IWNVQK---GKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSS 501
Query: 375 D 375
D
Sbjct: 502 D 502
Score = 31.6 bits (70), Expect = 1.5
Identities = 10/41 (24%), Positives = 23/41 (56%)
Query: 347 ATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVER 387
A +H +T++ W P + +FA+ D+ + W++A ++
Sbjct: 77 AIMSEHKKTITAISWCPHNPDLFASGSTDNLVIIWNVAEQK 117
Score = 30.4 bits (67), Expect = 3.4
Identities = 24/110 (21%), Positives = 43/110 (39%), Gaps = 6/110 (5%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS-R 318
H +++ + W P +FAS S D + IW++ ++ ++ + G +SW
Sbjct: 82 HKKTITAISWCPHNPDLFASGSTDNLVIIWNV----AEQKVIAKLDSTKGIPASLSWCWN 137
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPV-ATFKQHVAPVTSVEWHPQDSG 367
E + G L IW + SG V ++ + WH G
Sbjct: 138 AEDVVAFVSHRGPLFIWTISGPDSGVIVHKDAHSFLSDICMFRWHTHQKG 187
>gi|58331266 WD repeat domain 59 [Homo sapiens]
Length = 974
Score = 73.2 bits (178), Expect = 5e-13
Identities = 36/124 (29%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Query: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR 318
GHTR + DL W+ E + + S D I IWDI+ T A + + + W++
Sbjct: 103 GHTRVISDLDWAVFEPDLLVTSSVDTYIYIWDIKDTRKP----TVALSAVAGASQVKWNK 158
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQI 378
+ L+ DG ++IWD R K + V H++ + ++WHP + A S D+ +
Sbjct: 159 KNANCLATSHDGDVRIWDKR--KPSTAVEYLAAHLSKIHGLDWHPDSEHILATSSQDNSV 216
Query: 379 TQWD 382
WD
Sbjct: 217 KFWD 220
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/133 (27%), Positives = 52/133 (39%), Gaps = 28/133 (21%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSK-----ACMLTTATAH-----DG 309
H + L W P + A+ S D S++ WD R P K C + A +G
Sbjct: 190 HLSKIHGLDWHPDSEHILATSSQDNSVKFWDYR-QPRKYLNILPCQVPVWKARYTPFSNG 248
Query: 310 DVNV-ISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGV 368
V V + RRE LL +W++ F +PV TF H V +W Q G
Sbjct: 249 LVTVMVPQLRRENSLL---------LWNV--FDLNTPVHTFVGHDDVVLEFQWRKQKEG- 296
Query: 369 FAASGADHQITQW 381
D+Q+ W
Sbjct: 297 ----SKDYQLVTW 305
Score = 30.4 bits (67), Expect = 3.4
Identities = 18/82 (21%), Positives = 34/82 (41%), Gaps = 3/82 (3%)
Query: 310 DVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVA--TFKQHVAPVTSVEWHPQDSG 367
D+ + W+ + F ++ DL ++K GS T + H ++ ++W +
Sbjct: 61 DIGAVQWNPHDSFAHYFAASSNQRV-DLYKWKDGSGEVGTTLQGHTRVISDLDWAVFEPD 119
Query: 368 VFAASGADHQITQWDLAVERDP 389
+ S D I WD+ R P
Sbjct: 120 LLVTSSVDTYIYIWDIKDTRKP 141
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 71.2 bits (173), Expect = 2e-12
Identities = 50/173 (28%), Positives = 77/173 (44%), Gaps = 24/173 (13%)
Query: 253 DQRPFVGHTRSVEDLQWSPTENTVFA-SCSADASIRIWDIRAAPSKACMLTTATAHDGDV 311
++R GH V+ + W PT+ V + S + I+ WD + S L T AH V
Sbjct: 236 EERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQS----LATLHAHKNTV 291
Query: 312 NVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAA 371
+ + +LL+ D K++D+R K V F+ H T+V WHP G+FA+
Sbjct: 292 MEVKLNLNGNWLLTASRDHLCKLFDIRNLKEELQV--FRGHKKEATAVAWHPVHEGLFAS 349
Query: 372 SGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHP 424
G+D + W + VE+ E G +E H+G + L WHP
Sbjct: 350 GGSDGSLLFWHVGVEK--EVGGME-------------MAHEG--MIWSLAWHP 385
Score = 43.9 bits (102), Expect = 3e-04
Identities = 37/165 (22%), Positives = 58/165 (35%), Gaps = 45/165 (27%)
Query: 212 GHMGEGFALDWSPRVTGRLLTG--DCQKNIHLWTPTDG---------------------G 248
GH + +DW P G +++G D Q+ I W P G G
Sbjct: 242 GHGADVKCVDWHP-TKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNG 300
Query: 249 SWHV------------------DQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWD 290
+W + + + F GH + + W P +FAS +D S+ W
Sbjct: 301 NWLLTASRDHLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWH 360
Query: 291 IRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIW 335
+ M AH+G + ++W L SG +D K W
Sbjct: 361 VGVEKEVGGM---EMAHEGMIWSLAWHPLGHILCSGSNDHTSKFW 402
Score = 37.7 bits (86), Expect = 0.021
Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 5/81 (6%)
Query: 302 TTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEW 361
T AHD V ++WS + ++L+ G +K W + + V F+ H + +
Sbjct: 155 TILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ----SNMNNVKMFQAHKEAIREASF 210
Query: 362 HPQDSGVFAASGADHQITQWD 382
P D+ FA D + WD
Sbjct: 211 SPTDN-KFATCSDDGTVRIWD 230
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 67.8 bits (164), Expect = 2e-11
Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 15/167 (8%)
Query: 219 ALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFA 278
ALD P T ++LTG KN+ ++ D S + GHT+ V + + P+++ VF
Sbjct: 226 ALDLCPSDTNKILTGGADKNVVVF---DKSSEQI-LATLKGHTKKVTSVVFHPSQDLVF- 280
Query: 279 SCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLR 338
S S DA+IRIW + P+ +C + AH+ V +S +LLS DD + W
Sbjct: 281 SASPDATIRIWSV---PNASC-VQVVRAHESAVTGLSLHATGDYLLSSSDD---QYWAFS 333
Query: 339 QFKSGSPV--ATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDL 383
++G + T + +T ++HP D +F D QI WDL
Sbjct: 334 DIQTGRVLTKVTDETSGCSLTCAQFHP-DGLIFGTGTMDSQIKIWDL 379
Score = 46.2 bits (108), Expect = 6e-05
Identities = 20/70 (28%), Positives = 39/70 (55%), Gaps = 4/70 (5%)
Query: 273 ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGAL 332
+ +F + + D+ I+IWD++ + A H G + I++S +L + DD ++
Sbjct: 361 DGLIFGTGTMDSQIKIWDLKERTNVA----NFPGHSGPITSIAFSENGYYLATAADDSSV 416
Query: 333 KIWDLRQFKS 342
K+WDLR+ K+
Sbjct: 417 KLWDLRKLKN 426
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.0 bits (162), Expect = 3e-11
Identities = 47/177 (26%), Positives = 84/177 (47%), Gaps = 14/177 (7%)
Query: 208 FSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDL 267
F+ AGH ++ +SP L + K I +W DG ++ GH + D+
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGKF----EKTISGHKLGISDV 93
Query: 268 QWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGG 327
WS +++ + S S D +++IWD+ S L T H V +++ + ++SG
Sbjct: 94 AWS-SDSNLLVSASDDKTLKIWDV----SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 148
Query: 328 DDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLA 384
D +++IWD+ K+G + T H PV++V ++ +D + +S D WD A
Sbjct: 149 FDESVRIWDV---KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTA 201
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR 318
GHT++V +++SP + AS SAD I+IW + T + H ++ ++WS
Sbjct: 43 GHTKAVSSVKFSPNGEWL-ASSSADKLIKIWGAYDGKFEK----TISGHKLGISDVAWSS 97
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQI 378
L+S DD LKIWD+ SG + T K H V ++PQ S + + D +
Sbjct: 98 DSNLLVSASDDKTLKIWDV---SSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESV 153
Query: 379 TQWDLAVERDPEAGDVEADP 398
WD+ + + +DP
Sbjct: 154 RIWDVKTGKCLKTLPAHSDP 173
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 14/154 (9%)
Query: 230 LLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIW 289
L++ K + +W + G + GH+ V ++P N + S S D S+RIW
Sbjct: 102 LVSASDDKTLKIWDVSSGKCL----KTLKGHSNYVFCCNFNPQSNLI-VSGSFDESVRIW 156
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVAT- 348
D++ L T AH V+ + ++R ++S DG +IWD SG + T
Sbjct: 157 DVKTGKC----LKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT---ASGQCLKTL 209
Query: 349 FKQHVAPVTSVEWHPQDSGVFAASGADHQITQWD 382
PV+ V++ P + AA+ D+ + WD
Sbjct: 210 IDDDNPPVSFVKFSPNGKYILAAT-LDNTLKLWD 242
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/148 (20%), Positives = 65/148 (43%), Gaps = 12/148 (8%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSV 264
K + + GH F +++P+ + +++G +++ +W G + H+ V
Sbjct: 120 KCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKTGKCL----KTLPAHSDPV 174
Query: 265 EDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLL 324
+ ++ + ++ S S D RIWD S C+ T + V+ + +S ++L
Sbjct: 175 SAVHFN-RDGSLIVSSSYDGLCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 230
Query: 325 SGGDDGALKIWDLRQFKSGSPVATFKQH 352
+ D LK+WD + G + T+ H
Sbjct: 231 AATLDNTLKLWD---YSKGKCLKTYTGH 255
Score = 32.0 bits (71), Expect = 1.2
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 264 VEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS---RRE 320
V +++SP + A+ + D ++++WD SK L T T H + I +
Sbjct: 217 VSFVKFSPNGKYILAA-TLDNTLKLWDY----SKGKCLKTYTGHKNEKYCIFANFSVTGG 271
Query: 321 PFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
+++SG +D + IW+L ++ V + H V S HP ++ + +A+
Sbjct: 272 KWIVSGSEDNLVYIWNL---QTKEIVQKLQGHTDVVISTACHPTENIIASAA 320
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 67.0 bits (162), Expect = 3e-11
Identities = 47/177 (26%), Positives = 84/177 (47%), Gaps = 14/177 (7%)
Query: 208 FSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDL 267
F+ AGH ++ +SP L + K I +W DG ++ GH + D+
Sbjct: 39 FTLAGHTKAVSSVKFSPNGEW-LASSSADKLIKIWGAYDGKF----EKTISGHKLGISDV 93
Query: 268 QWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGG 327
WS +++ + S S D +++IWD+ S L T H V +++ + ++SG
Sbjct: 94 AWS-SDSNLLVSASDDKTLKIWDV----SSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGS 148
Query: 328 DDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLA 384
D +++IWD+ K+G + T H PV++V ++ +D + +S D WD A
Sbjct: 149 FDESVRIWDV---KTGKCLKTLPAHSDPVSAVHFN-RDGSLIVSSSYDGLCRIWDTA 201
Score = 60.8 bits (146), Expect = 2e-09
Identities = 41/140 (29%), Positives = 66/140 (47%), Gaps = 9/140 (6%)
Query: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR 318
GHT++V +++SP + AS SAD I+IW + T + H ++ ++WS
Sbjct: 43 GHTKAVSSVKFSPNGEWL-ASSSADKLIKIWGAYDGKFEK----TISGHKLGISDVAWSS 97
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQI 378
L+S DD LKIWD+ SG + T K H V ++PQ S + + D +
Sbjct: 98 DSNLLVSASDDKTLKIWDV---SSGKCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESV 153
Query: 379 TQWDLAVERDPEAGDVEADP 398
WD+ + + +DP
Sbjct: 154 RIWDVKTGKCLKTLPAHSDP 173
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/154 (26%), Positives = 69/154 (44%), Gaps = 14/154 (9%)
Query: 230 LLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIW 289
L++ K + +W + G + GH+ V ++P N + S S D S+RIW
Sbjct: 102 LVSASDDKTLKIWDVSSGKCL----KTLKGHSNYVFCCNFNPQSNLI-VSGSFDESVRIW 156
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVAT- 348
D++ L T AH V+ + ++R ++S DG +IWD SG + T
Sbjct: 157 DVKTGKC----LKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDT---ASGQCLKTL 209
Query: 349 FKQHVAPVTSVEWHPQDSGVFAASGADHQITQWD 382
PV+ V++ P + AA+ D+ + WD
Sbjct: 210 IDDDNPPVSFVKFSPNGKYILAAT-LDNTLKLWD 242
Score = 41.6 bits (96), Expect = 0.001
Identities = 31/148 (20%), Positives = 65/148 (43%), Gaps = 12/148 (8%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSV 264
K + + GH F +++P+ + +++G +++ +W G + H+ V
Sbjct: 120 KCLKTLKGHSNYVFCCNFNPQ-SNLIVSGSFDESVRIWDVKTGKCL----KTLPAHSDPV 174
Query: 265 EDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLL 324
+ ++ + ++ S S D RIWD S C+ T + V+ + +S ++L
Sbjct: 175 SAVHFN-RDGSLIVSSSYDGLCRIWD---TASGQCLKTLIDDDNPPVSFVKFSPNGKYIL 230
Query: 325 SGGDDGALKIWDLRQFKSGSPVATFKQH 352
+ D LK+WD + G + T+ H
Sbjct: 231 AATLDNTLKLWD---YSKGKCLKTYTGH 255
Score = 32.0 bits (71), Expect = 1.2
Identities = 27/112 (24%), Positives = 53/112 (47%), Gaps = 11/112 (9%)
Query: 264 VEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS---RRE 320
V +++SP + A+ + D ++++WD SK L T T H + I +
Sbjct: 217 VSFVKFSPNGKYILAA-TLDNTLKLWDY----SKGKCLKTYTGHKNEKYCIFANFSVTGG 271
Query: 321 PFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
+++SG +D + IW+L ++ V + H V S HP ++ + +A+
Sbjct: 272 KWIVSGSEDNLVYIWNL---QTKEIVQKLQGHTDVVISTACHPTENIIASAA 320
>gi|62234438 Notchless gene homolog isoform b [Homo sapiens]
Length = 193
Score = 67.0 bits (162), Expect = 3e-11
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 18/156 (11%)
Query: 229 RLLTGDCQKNIHLWTPTDGGSWHVDQRPFV---GHTRSVEDLQWSPTENTVFASCSADAS 285
RL++G + LW+P + D++P GH + + +SP ++ + AS S D S
Sbjct: 51 RLVSGSDDFTLFLWSPAE------DKKPLTRMTGHQALINQVLFSP-DSRIVASASFDKS 103
Query: 286 IRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSP 345
I++WD R L + H V I+WS L+SG D LK+WD++ K
Sbjct: 104 IKLWDGRTGK----YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 159
Query: 346 VATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
+ H V +V+W P V A+ G D + W
Sbjct: 160 L---PGHADEVYAVDWSPDGQRV-ASGGKDKCLRIW 191
>gi|62234461 Notchless gene homolog isoform a [Homo sapiens]
Length = 485
Score = 67.0 bits (162), Expect = 3e-11
Identities = 46/156 (29%), Positives = 72/156 (46%), Gaps = 18/156 (11%)
Query: 229 RLLTGDCQKNIHLWTPTDGGSWHVDQRPFV---GHTRSVEDLQWSPTENTVFASCSADAS 285
RL++G + LW+P + D++P GH + + +SP ++ + AS S D S
Sbjct: 343 RLVSGSDDFTLFLWSPAE------DKKPLTRMTGHQALINQVLFSP-DSRIVASASFDKS 395
Query: 286 IRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSP 345
I++WD R L + H V I+WS L+SG D LK+WD++ K
Sbjct: 396 IKLWDGRTGK----YLASLRGHVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMD 451
Query: 346 VATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
+ H V +V+W P V A+ G D + W
Sbjct: 452 L---PGHADEVYAVDWSPDGQRV-ASGGKDKCLRIW 483
Score = 59.3 bits (142), Expect = 7e-09
Identities = 42/135 (31%), Positives = 57/135 (42%), Gaps = 15/135 (11%)
Query: 206 PIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKN-IHLWTPTDGGSWHVDQRPFVGHTRSV 264
P F+ GH ++ WSP GR L C+ I LW P+ G R GH++ +
Sbjct: 148 PHFTCKGHRHWVLSISWSP--DGRKLASGCKNGQILLWDPSTGKQVG---RTLAGHSKWI 202
Query: 265 EDLQWSPT----ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRRE 320
L W P E AS S D S+RIWD A + + T H V + W +
Sbjct: 203 TGLSWEPLHANPECRYVASSSKDGSVRIWDTTAGRCERIL----TGHTQSVTCLRWG-GD 257
Query: 321 PFLLSGGDDGALKIW 335
L S D +K+W
Sbjct: 258 GLLYSASQDRTIKVW 272
Score = 48.1 bits (113), Expect = 2e-05
Identities = 40/134 (29%), Positives = 56/134 (41%), Gaps = 13/134 (9%)
Query: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR 318
GH+ +V + +SPT AS S D ++R WD+ S T H V ISWS
Sbjct: 112 GHSEAVISVAFSPT-GKYLASGSGDTTVRFWDL----STETPHFTCKGHRHWVLSISWSP 166
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVA-TFKQHVAPVTSVEWHP----QDSGVFAASG 373
L SG +G + +WD +G V T H +T + W P + A+S
Sbjct: 167 DGRKLASGCKNGQILLWDP---STGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 223
Query: 374 ADHQITQWDLAVER 387
D + WD R
Sbjct: 224 KDGSVRIWDTTAGR 237
>gi|83779014 katanin p80 subunit B 1 [Homo sapiens]
Length = 655
Score = 66.6 bits (161), Expect = 4e-11
Identities = 62/246 (25%), Positives = 107/246 (43%), Gaps = 38/246 (15%)
Query: 138 KPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEVFALRRLLQVVEEPQALAAFL 197
KP +++ H + VR++ E VAG S+ G + V+ L A L
Sbjct: 52 KPNCIMSLTGHTSPVESVRLNTPEELIVAG--SQSGSIRVWDLEA-----------AKIL 98
Query: 198 RDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLL-TGDCQKNIHLWTPTDGGSWHVDQRP 256
R + GH +LD+ P G + +G NI LW G
Sbjct: 99 R----------TLMGHKANICSLDFHPY--GEFVASGSQDTNIKLWDIRRKGCVF----R 142
Query: 257 FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISW 316
+ GH+++V L++SP + AS + D ++++WD+ A M++ H G VNV+ +
Sbjct: 143 YRGHSQAVRCLRFSP-DGKWLASAADDHTVKLWDLTAGK----MMSEFPGHTGPVNVVEF 197
Query: 317 SRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADH 376
E L SG D ++ WDL +F+ V+ + PV SV ++P +++
Sbjct: 198 HPNEYLLASGSSDRTIRFWDLEKFQ---VVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSL 254
Query: 377 QITQWD 382
++ W+
Sbjct: 255 RVYGWE 260
Score = 55.5 bits (132), Expect = 1e-07
Identities = 35/136 (25%), Positives = 62/136 (45%), Gaps = 12/136 (8%)
Query: 249 SWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHD 308
+W + + V H +V L + A+ D + +W I +K + + T H
Sbjct: 10 AWKLQE--IVAHASNVSSLVLGKASGRLLATGGDDCRVNLWSI----NKPNCIMSLTGHT 63
Query: 309 GDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGV 368
V + + E +++G G++++WDL K + T H A + S+++HP G
Sbjct: 64 SPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKI---LRTLMGHKANICSLDFHPY--GE 118
Query: 369 FAASGA-DHQITQWDL 383
F ASG+ D I WD+
Sbjct: 119 FVASGSQDTNIKLWDI 134
>gi|14149987 WD repeat domain 24 [Homo sapiens]
Length = 790
Score = 66.2 bits (160), Expect = 6e-11
Identities = 44/171 (25%), Positives = 73/171 (42%), Gaps = 24/171 (14%)
Query: 257 FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISW 316
F H R+V + + PTE V S S D ++ +D+R S ++T + V + +
Sbjct: 116 FTEHKRTVNKVCFHPTEAHVLLSGSQDGFMKCFDLRRKDS----VSTFSGQSESVRDVQF 171
Query: 317 SRREPFLLSGG-DDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGAD 375
S R+ F + ++G +++WD+R + F H PV +WHP+D G A G D
Sbjct: 172 SIRDYFTFASTFENGNVQLWDIR--RPDRCERMFTAHNGPVFCCDWHPEDRGWLATGGRD 229
Query: 376 HQITQWDLAVERDPEAGDVEADPGLADLPQQLLFVHQGETELKELHWHPQC 426
+ WD+ R E V+ +A + W P+C
Sbjct: 230 KMVKVWDMTTHRAKEMHCVQTIASVA-----------------RVKWRPEC 263
Score = 50.8 bits (120), Expect = 2e-06
Identities = 41/129 (31%), Positives = 53/129 (41%), Gaps = 14/129 (10%)
Query: 210 FAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQW 269
F H G F DW P G L TG K + +W T + + V SV ++W
Sbjct: 203 FTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVWDMT---THRAKEMHCVQTIASVARVKW 259
Query: 270 SPTENTVFASCS--ADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP----FL 323
P A+CS D +I +WD+R A M H I+W R P FL
Sbjct: 260 RPECRHHLATCSMMVDHNIYVWDVRRPFVPAAMF---EEHRDVTTGIAW--RHPHDPSFL 314
Query: 324 LSGGDDGAL 332
LSG D +L
Sbjct: 315 LSGSKDSSL 323
Score = 47.0 bits (110), Expect = 4e-05
Identities = 50/217 (23%), Positives = 78/217 (35%), Gaps = 37/217 (17%)
Query: 170 SEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGR 229
S+ G ++ F LRR V + +RD Q ++ F+FA G W R R
Sbjct: 140 SQDGFMKCFDLRRK-DSVSTFSGQSESVRDVQFSIRDYFTFASTFENGNVQLWDIRRPDR 198
Query: 230 LLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIW 289
+R F H V W P + A+ D +++W
Sbjct: 199 C-----------------------ERMFTAHNGPVFCCDWHPEDRGWLATGGRDKMVKVW 235
Query: 290 DIRAAPSKA--CMLTTATAHDGDVNVISW---SRREPFLLSGGDDGALKIWDLRQFKSGS 344
D+ +K C+ T A+ V + W R S D + +WD+R +
Sbjct: 236 DMTTHRAKEMHCVQTIAS-----VARVKWRPECRHHLATCSMMVDHNIYVWDVR--RPFV 288
Query: 345 PVATFKQHVAPVTSVEW-HPQDSGVFAASGADHQITQ 380
P A F++H T + W HP D + D + Q
Sbjct: 289 PAAMFEEHRDVTTGIAWRHPHDPSFLLSGSKDSSLCQ 325
>gi|7657439 PCAF associated factor 65 beta isoform a [Homo sapiens]
Length = 589
Score = 65.9 bits (159), Expect = 7e-11
Identities = 41/138 (29%), Positives = 71/138 (51%), Gaps = 13/138 (9%)
Query: 250 WHVDQ----RPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTAT 305
W D+ R + GH V+ +++ P N + A+ S D ++R+W + S + T
Sbjct: 411 WSFDRTYPLRIYAGHLADVDCVKFHPNSNYL-ATGSTDKTVRLWSAQQGNS----VRLFT 465
Query: 306 AHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQD 365
H G V +++S +L S G+D LK+WDL SG+ + H +TS+ + P D
Sbjct: 466 GHRGPVLSLAFSPNGKYLASAGEDQRLKLWDL---ASGTLYKELRGHTDNITSLTFSP-D 521
Query: 366 SGVFAASGADHQITQWDL 383
SG+ A++ D+ + WD+
Sbjct: 522 SGLIASASMDNSVRVWDI 539
Score = 60.1 bits (144), Expect = 4e-09
Identities = 60/217 (27%), Positives = 96/217 (44%), Gaps = 24/217 (11%)
Query: 170 SEKGQVEVFALRRLLQVVEEPQALAAFLRDEQA--QMKPIFSFAGHMGEGFALDWSPRVT 227
SE QV+V + ++EE D+ A +MK + GH G ++ + +
Sbjct: 304 SEPHQVDVSRIHLACDILEEEDD-----EDDNAGTEMKIL---RGHCGPVYSTRFLADSS 355
Query: 228 GRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIR 287
G LL+ +I W D GS+ + + GH V DL SP + FAS S D + R
Sbjct: 356 G-LLSCSEDMSIRYW---DLGSF-TNTVLYQGHAYPVWDLDISPY-SLYFASGSHDRTAR 409
Query: 288 IWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVA 347
+W + L H DV+ + + +L +G D +++W +Q G+ V
Sbjct: 410 LWSF----DRTYPLRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQ---GNSVR 462
Query: 348 TFKQHVAPVTSVEWHPQDSGVFAASGADHQITQWDLA 384
F H PV S+ + P A++G D ++ WDLA
Sbjct: 463 LFTGHRGPVLSLAFSPNGK-YLASAGEDQRLKLWDLA 498
Score = 56.6 bits (135), Expect = 4e-08
Identities = 34/140 (24%), Positives = 62/140 (44%), Gaps = 10/140 (7%)
Query: 206 PIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVE 265
P+ +AGH+ + + + P + L TG K + LW+ G S R F GH V
Sbjct: 418 PLRIYAGHLADVDCVKFHPN-SNYLATGSTDKTVRLWSAQQGNS----VRLFTGHRGPVL 472
Query: 266 DLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLS 325
L +SP AS D +++WD+ + + H ++ +++S + S
Sbjct: 473 SLAFSPN-GKYLASAGEDQRLKLWDL----ASGTLYKELRGHTDNITSLTFSPDSGLIAS 527
Query: 326 GGDDGALKIWDLRQFKSGSP 345
D ++++WD+R +P
Sbjct: 528 ASMDNSVRVWDIRNTYCSAP 547
Score = 45.1 bits (105), Expect = 1e-04
Identities = 34/111 (30%), Positives = 54/111 (48%), Gaps = 11/111 (9%)
Query: 210 FAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQW 269
F GH G +L +SP G+ Q+ + LW G + + GHT ++ L +
Sbjct: 464 FTGHRGPVLSLAFSPNGKYLASAGEDQR-LKLWDLASGTLY----KELRGHTDNITSLTF 518
Query: 270 SPTENTVFASCSADASIRIWDIR----AAPSKACMLTTATAHDGDV-NVIS 315
SP ++ + AS S D S+R+WDIR +AP+ + G + NV+S
Sbjct: 519 SP-DSGLIASASMDNSVRVWDIRNTYCSAPADGSSSELVGVYTGQMSNVLS 568
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 19/188 (10%)
Query: 204 MKP---IFSFAGHMGEGFALDWSPRVTGRLL-TGDCQKNIHLWTPTDGGSWHVDQRPFVG 259
MKP + F GH +++SP +G LL +G K + +W P G V F
Sbjct: 10 MKPQSRAYRFTGHKDAVTCVNFSP--SGHLLASGSRDKTVRIWVPNVKGESTV----FRA 63
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
HT +V + + ++ F + S D ++++W A + L + + H V +S
Sbjct: 64 HTATVRSVHFC-SDGQSFVTASDDKTVKVW----ATHRQKFLFSLSQHINWVRCAKFSPD 118
Query: 320 EPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQIT 379
++S DD +K+WD S V ++ +H VT V++HP + + AA+G D+ +
Sbjct: 119 GRLIVSASDDKTVKLWDK---SSRECVHSYCEHGGFVTYVDFHPSGTCI-AAAGMDNTVK 174
Query: 380 QWDLAVER 387
WD+ R
Sbjct: 175 VWDVRTHR 182
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
H+ +V L + P+ N + + S+D++++I D+ + +L T H G +++SR
Sbjct: 190 HSAAVNGLSFHPSGNYLITA-SSDSTLKILDLM----EGRLLYTLHGHQGPATTVAFSRT 244
Query: 320 EPFLLSGGDDGALKIW 335
+ SGG D + +W
Sbjct: 245 GEYFASGGSDEQVMVW 260
Score = 31.2 bits (69), Expect = 2.0
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 8/99 (8%)
Query: 283 DASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKS 342
D+ + +W ++ S+A T H V +++S L SG D ++IW + K
Sbjct: 2 DSCLMVWHMKPQ-SRAYRFT---GHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKG 56
Query: 343 GSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
S V F+ H A V SV + D F + D + W
Sbjct: 57 ESTV--FRAHTATVRSVHF-CSDGQSFVTASDDKTVKVW 92
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 19/188 (10%)
Query: 204 MKP---IFSFAGHMGEGFALDWSPRVTGRLL-TGDCQKNIHLWTPTDGGSWHVDQRPFVG 259
MKP + F GH +++SP +G LL +G K + +W P G V F
Sbjct: 48 MKPQSRAYRFTGHKDAVTCVNFSP--SGHLLASGSRDKTVRIWVPNVKGESTV----FRA 101
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
HT +V + + ++ F + S D ++++W A + L + + H V +S
Sbjct: 102 HTATVRSVHFC-SDGQSFVTASDDKTVKVW----ATHRQKFLFSLSQHINWVRCAKFSPD 156
Query: 320 EPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQIT 379
++S DD +K+WD S V ++ +H VT V++HP + + AA+G D+ +
Sbjct: 157 GRLIVSASDDKTVKLWDK---SSRECVHSYCEHGGFVTYVDFHPSGTCI-AAAGMDNTVK 212
Query: 380 QWDLAVER 387
WD+ R
Sbjct: 213 VWDVRTHR 220
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
H+ +V L + P+ N + + S+D++++I D+ + +L T H G +++SR
Sbjct: 228 HSAAVNGLSFHPSGNYLITA-SSDSTLKILDLM----EGRLLYTLHGHQGPATTVAFSRT 282
Query: 320 EPFLLSGGDDGALKIW 335
+ SGG D + +W
Sbjct: 283 GEYFASGGSDEQVMVW 298
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 9/128 (7%)
Query: 254 QRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+R F GH +V + +S + AS S D+ + +W ++ S+A T H V
Sbjct: 12 ERHFKGHRDAVTCVDFSINTKQL-ASGSMDSCLMVWHMKPQ-SRAYRFT---GHKDAVTC 66
Query: 314 ISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASG 373
+++S L SG D ++IW + K S V F+ H A V SV + D F +
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV--FRAHTATVRSVHF-CSDGQSFVTAS 122
Query: 374 ADHQITQW 381
D + W
Sbjct: 123 DDKTVKVW 130
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 65.1 bits (157), Expect = 1e-10
Identities = 51/188 (27%), Positives = 88/188 (46%), Gaps = 19/188 (10%)
Query: 204 MKP---IFSFAGHMGEGFALDWSPRVTGRLL-TGDCQKNIHLWTPTDGGSWHVDQRPFVG 259
MKP + F GH +++SP +G LL +G K + +W P G V F
Sbjct: 48 MKPQSRAYRFTGHKDAVTCVNFSP--SGHLLASGSRDKTVRIWVPNVKGESTV----FRA 101
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
HT +V + + ++ F + S D ++++W A + L + + H V +S
Sbjct: 102 HTATVRSVHFC-SDGQSFVTASDDKTVKVW----ATHRQKFLFSLSQHINWVRCAKFSPD 156
Query: 320 EPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQIT 379
++S DD +K+WD S V ++ +H VT V++HP + + AA+G D+ +
Sbjct: 157 GRLIVSASDDKTVKLWDK---SSRECVHSYCEHGGFVTYVDFHPSGTCI-AAAGMDNTVK 212
Query: 380 QWDLAVER 387
WD+ R
Sbjct: 213 VWDVRTHR 220
Score = 38.9 bits (89), Expect = 0.010
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 5/76 (6%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRR 319
H+ +V L + P+ N + + S+D++++I D+ + +L T H G +++SR
Sbjct: 228 HSAAVNGLSFHPSGNYLITA-SSDSTLKILDLM----EGRLLYTLHGHQGPATTVAFSRT 282
Query: 320 EPFLLSGGDDGALKIW 335
+ SGG D + +W
Sbjct: 283 GEYFASGGSDEQVMVW 298
Score = 38.5 bits (88), Expect = 0.012
Identities = 36/128 (28%), Positives = 57/128 (44%), Gaps = 9/128 (7%)
Query: 254 QRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+R F GH +V + +S + AS S D+ + +W ++ S+A T H V
Sbjct: 12 ERHFKGHRDAVTCVDFSINTKQL-ASGSMDSCLMVWHMKPQ-SRAYRFT---GHKDAVTC 66
Query: 314 ISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASG 373
+++S L SG D ++IW + K S V F+ H A V SV + D F +
Sbjct: 67 VNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV--FRAHTATVRSVHF-CSDGQSFVTAS 122
Query: 374 ADHQITQW 381
D + W
Sbjct: 123 DDKTVKVW 130
>gi|4757988 WD repeat domain 39 [Homo sapiens]
Length = 339
Score = 65.1 bits (157), Expect = 1e-10
Identities = 50/189 (26%), Positives = 77/189 (40%), Gaps = 29/189 (15%)
Query: 220 LDWSPRVTGRLLTGDC--QKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVF 277
L W+P T L C + I +W T+G SW GH R+V + WSP N +
Sbjct: 22 LAWNPAGT---LLASCGGDRRIRIWG-TEGDSWICKSVLSEGHQRTVRKVAWSPCGNYL- 76
Query: 278 ASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDL 337
AS S DA+ IW + +TT H+ +V ++W+ L + D ++ +W++
Sbjct: 77 ASASFDATTCIWKKNQDDFEC--VTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEV 134
Query: 338 RQFKSGSPVATFKQHVAPVTSVEWHP--------------------QDSGVFAASGADHQ 377
+ V+ H V V WHP +D V A+ H+
Sbjct: 135 DEEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHE 194
Query: 378 ITQWDLAVE 386
T W LA +
Sbjct: 195 STVWSLAFD 203
Score = 48.5 bits (114), Expect = 1e-05
Identities = 62/278 (22%), Positives = 109/278 (39%), Gaps = 58/278 (20%)
Query: 192 ALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWH 251
A + Q + + + GH E ++ W+P +G LL C ++ +W W
Sbjct: 83 ATTCIWKKNQDDFECVTTLEGHENEVKSVAWAP--SGNLLA-TCSRDKSVWV------WE 133
Query: 252 VDQRP-------FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTA 304
VD+ HT+ V+ + W P++ + AS S D +++++ C T
Sbjct: 134 VDEEDEYECVSVLNSHTQDVKHVVWHPSQE-LLASASYDDTVKLYREEEDDWVCC--ATL 190
Query: 305 TAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSP--------------VATFK 350
H+ V +++ L S DD ++IW RQ+ G+ + T
Sbjct: 191 EGHESTVWSLAFDPSGQRLASCSDDRTVRIW--RQYLPGNEQGVACSGSDPSWKCICTLS 248
Query: 351 Q-HVAPVTSVEWHPQDSGVFAASGADHQITQWDLAVERDPEAGDVEADPGLADLPQQLLF 409
H + + W Q +G A + D I + + DP + PQQ F
Sbjct: 249 GFHSRTIYDIAWC-QLTGALATACGDDAIRVF----QEDPNSD-----------PQQPTF 292
Query: 410 -----VHQGETE-LKELHWHPQCPGLLVSTALSGFTIF 441
+HQ ++ + + W+P+ PGLL S + G F
Sbjct: 293 SLTAHLHQAHSQDVNCVAWNPKEPGLLASCSDDGEVAF 330
Score = 46.6 bits (109), Expect = 5e-05
Identities = 28/82 (34%), Positives = 43/82 (52%), Gaps = 7/82 (8%)
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIW--DIRAAPSKACMLTTA---TAHDGDVNVI 314
H+R++ D+ W + +C DA IR++ D + P + TA AH DVN +
Sbjct: 251 HSRTIYDIAWCQLTGALATACGDDA-IRVFQEDPNSDPQQPTFSLTAHLHQAHSQDVNCV 309
Query: 315 SWSRREPFLL-SGGDDGALKIW 335
+W+ +EP LL S DDG + W
Sbjct: 310 AWNPKEPGLLASCSDDGEVAFW 331
Score = 31.6 bits (70), Expect = 1.5
Identities = 15/46 (32%), Positives = 23/46 (50%), Gaps = 4/46 (8%)
Query: 244 PTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIW 289
PT + H+ Q H++ V + W+P E + ASCS D + W
Sbjct: 290 PTFSLTAHLHQ----AHSQDVNCVAWNPKEPGLLASCSDDGEVAFW 331
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/186 (28%), Positives = 79/186 (42%), Gaps = 22/186 (11%)
Query: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWT---PTDGGSWHVDQRPFV---GH----T 261
GH E F W+P V+ L +G +W ++GGS + R + GH
Sbjct: 179 GHESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP 321
+ V L W+ T T+ A+ S D RIW + +T H G + + W+R+
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWT-----EDGNLASTLGQHKGPIFALKWNRKGN 291
Query: 322 FLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
++LS G D IWD +G F H AP V+W Q++ FA+ D I
Sbjct: 292 YILSAGVDKTTIIWDAH---TGEAKQQFPFHSAPALDVDW--QNNTTFASCSTDMCIHVC 346
Query: 382 DLAVER 387
L +R
Sbjct: 347 RLGCDR 352
Score = 62.4 bits (150), Expect = 8e-10
Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 24/180 (13%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H G FAL W+ R +L+ K +W G + ++ F H+ D+ W
Sbjct: 277 HKGPIFALKWN-RKGNYILSAGVDKTTIIWDAHTGEA----KQQFPFHSAPALDVDWQ-- 329
Query: 273 ENTVFASCSADASIRIWDIRA-APSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGA 331
NT FASCS D I + + P K T H +VN I W L S DD
Sbjct: 330 NNTTFASCSTDMCIHVCRLGCDRPVK-----TFQGHTNEVNAIKWDPSGMLLASCSDDMT 384
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEW--------HPQDSGVFAASGADHQITQWDL 383
LKIW ++Q + + H + +++W +P + + A++ D + WD+
Sbjct: 385 LKIWSMKQEVC---IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 24/188 (12%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTG-DCQKNIHLWTPTDGGSWHVDQRPFVGHTRS 263
+P+ +F GH E A+ W P +G LL + +W+ H Q H +
Sbjct: 352 RPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWSMKQEVCIHDLQ----AHNKE 405
Query: 264 VEDLQWSPT--------ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVIS 315
+ ++WSPT N + AS S D+++R+WDI + T T H V ++
Sbjct: 406 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI----ERGVCTHTLTKHQEPVYSVA 461
Query: 316 WSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGAD 375
+S +L SG D + IW+ +SG+ V +++ + V W+ + V AS +D
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNT---QSGNLVHSYR-GTGGIFEVCWNARGDKV-GASASD 516
Query: 376 HQITQWDL 383
+ DL
Sbjct: 517 GSVCVLDL 524
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 16/96 (16%)
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATF 349
++ SKA +L H+ +V + +W+ L SG D +IW+L + +G
Sbjct: 166 EVEIPSSKATVLR---GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV 222
Query: 350 KQHV-----------APVTSVEWHPQDSGVFAASGA 374
+H VTS++W+ +G A+G+
Sbjct: 223 LRHCIREGGHDVPSNKDVTSLDWN--TNGTLLATGS 256
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/186 (28%), Positives = 79/186 (42%), Gaps = 22/186 (11%)
Query: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWT---PTDGGSWHVDQRPFV---GH----T 261
GH E F W+P V+ L +G +W ++GGS + R + GH
Sbjct: 179 GHESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 237
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP 321
+ V L W+ T T+ A+ S D RIW + +T H G + + W+R+
Sbjct: 238 KDVTSLDWN-TNGTLLATGSYDGFARIWT-----EDGNLASTLGQHKGPIFALKWNRKGN 291
Query: 322 FLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
++LS G D IWD +G F H AP V+W Q++ FA+ D I
Sbjct: 292 YILSAGVDKTTIIWDAH---TGEAKQQFPFHSAPALDVDW--QNNTTFASCSTDMCIHVC 346
Query: 382 DLAVER 387
L +R
Sbjct: 347 RLGCDR 352
Score = 62.4 bits (150), Expect = 8e-10
Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 24/180 (13%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H G FAL W+ R +L+ K +W G + ++ F H+ D+ W
Sbjct: 277 HKGPIFALKWN-RKGNYILSAGVDKTTIIWDAHTGEA----KQQFPFHSAPALDVDWQ-- 329
Query: 273 ENTVFASCSADASIRIWDIRA-APSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGA 331
NT FASCS D I + + P K T H +VN I W L S DD
Sbjct: 330 NNTTFASCSTDMCIHVCRLGCDRPVK-----TFQGHTNEVNAIKWDPSGMLLASCSDDMT 384
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEW--------HPQDSGVFAASGADHQITQWDL 383
LKIW ++Q + + H + +++W +P + + A++ D + WD+
Sbjct: 385 LKIWSMKQEVC---IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 441
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 24/188 (12%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTG-DCQKNIHLWTPTDGGSWHVDQRPFVGHTRS 263
+P+ +F GH E A+ W P +G LL + +W+ H Q H +
Sbjct: 352 RPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWSMKQEVCIHDLQ----AHNKE 405
Query: 264 VEDLQWSPT--------ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVIS 315
+ ++WSPT N + AS S D+++R+WDI + T T H V ++
Sbjct: 406 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI----ERGVCTHTLTKHQEPVYSVA 461
Query: 316 WSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGAD 375
+S +L SG D + IW+ +SG+ V +++ + V W+ + V AS +D
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNT---QSGNLVHSYR-GTGGIFEVCWNARGDKV-GASASD 516
Query: 376 HQITQWDL 383
+ DL
Sbjct: 517 GSVCVLDL 524
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 16/96 (16%)
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATF 349
++ SKA +L H+ +V + +W+ L SG D +IW+L + +G
Sbjct: 166 EVEIPSSKATVLR---GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV 222
Query: 350 KQHV-----------APVTSVEWHPQDSGVFAASGA 374
+H VTS++W+ +G A+G+
Sbjct: 223 LRHCIREGGHDVPSNKDVTSLDWN--TNGTLLATGS 256
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/186 (28%), Positives = 79/186 (42%), Gaps = 22/186 (11%)
Query: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWT---PTDGGSWHVDQRPFV---GH----T 261
GH E F W+P V+ L +G +W ++GGS + R + GH
Sbjct: 230 GHESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP 321
+ V L W+ T T+ A+ S D RIW + +T H G + + W+R+
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWT-----EDGNLASTLGQHKGPIFALKWNRKGN 342
Query: 322 FLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
++LS G D IWD +G F H AP V+W Q++ FA+ D I
Sbjct: 343 YILSAGVDKTTIIWDAH---TGEAKQQFPFHSAPALDVDW--QNNTTFASCSTDMCIHVC 397
Query: 382 DLAVER 387
L +R
Sbjct: 398 RLGCDR 403
Score = 62.4 bits (150), Expect = 8e-10
Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 24/180 (13%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H G FAL W+ R +L+ K +W G + ++ F H+ D+ W
Sbjct: 328 HKGPIFALKWN-RKGNYILSAGVDKTTIIWDAHTGEA----KQQFPFHSAPALDVDWQ-- 380
Query: 273 ENTVFASCSADASIRIWDIRA-APSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGA 331
NT FASCS D I + + P K T H +VN I W L S DD
Sbjct: 381 NNTTFASCSTDMCIHVCRLGCDRPVK-----TFQGHTNEVNAIKWDPSGMLLASCSDDMT 435
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEW--------HPQDSGVFAASGADHQITQWDL 383
LKIW ++Q + + H + +++W +P + + A++ D + WD+
Sbjct: 436 LKIWSMKQEVC---IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 24/188 (12%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTG-DCQKNIHLWTPTDGGSWHVDQRPFVGHTRS 263
+P+ +F GH E A+ W P +G LL + +W+ H Q H +
Sbjct: 403 RPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWSMKQEVCIHDLQ----AHNKE 456
Query: 264 VEDLQWSPT--------ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVIS 315
+ ++WSPT N + AS S D+++R+WDI + T T H V ++
Sbjct: 457 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI----ERGVCTHTLTKHQEPVYSVA 512
Query: 316 WSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGAD 375
+S +L SG D + IW+ +SG+ V +++ + V W+ + V AS +D
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNT---QSGNLVHSYR-GTGGIFEVCWNARGDKV-GASASD 567
Query: 376 HQITQWDL 383
+ DL
Sbjct: 568 GSVCVLDL 575
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 16/96 (16%)
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATF 349
++ SKA +L H+ +V + +W+ L SG D +IW+L + +G
Sbjct: 217 EVEIPSSKATVLR---GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV 273
Query: 350 KQHV-----------APVTSVEWHPQDSGVFAASGA 374
+H VTS++W+ +G A+G+
Sbjct: 274 LRHCIREGGHDVPSNKDVTSLDWN--TNGTLLATGS 307
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/186 (28%), Positives = 79/186 (42%), Gaps = 22/186 (11%)
Query: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWT---PTDGGSWHVDQRPFV---GH----T 261
GH E F W+P V+ L +G +W ++GGS + R + GH
Sbjct: 230 GHESEVFICAWNP-VSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSN 288
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP 321
+ V L W+ T T+ A+ S D RIW + +T H G + + W+R+
Sbjct: 289 KDVTSLDWN-TNGTLLATGSYDGFARIWT-----EDGNLASTLGQHKGPIFALKWNRKGN 342
Query: 322 FLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
++LS G D IWD +G F H AP V+W Q++ FA+ D I
Sbjct: 343 YILSAGVDKTTIIWDAH---TGEAKQQFPFHSAPALDVDW--QNNTTFASCSTDMCIHVC 397
Query: 382 DLAVER 387
L +R
Sbjct: 398 RLGCDR 403
Score = 62.4 bits (150), Expect = 8e-10
Identities = 48/180 (26%), Positives = 75/180 (41%), Gaps = 24/180 (13%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H G FAL W+ R +L+ K +W G + ++ F H+ D+ W
Sbjct: 328 HKGPIFALKWN-RKGNYILSAGVDKTTIIWDAHTGEA----KQQFPFHSAPALDVDWQ-- 380
Query: 273 ENTVFASCSADASIRIWDIRA-APSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGA 331
NT FASCS D I + + P K T H +VN I W L S DD
Sbjct: 381 NNTTFASCSTDMCIHVCRLGCDRPVK-----TFQGHTNEVNAIKWDPSGMLLASCSDDMT 435
Query: 332 LKIWDLRQFKSGSPVATFKQHVAPVTSVEW--------HPQDSGVFAASGADHQITQWDL 383
LKIW ++Q + + H + +++W +P + + A++ D + WD+
Sbjct: 436 LKIWSMKQEVC---IHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI 492
Score = 60.1 bits (144), Expect = 4e-09
Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 24/188 (12%)
Query: 205 KPIFSFAGHMGEGFALDWSPRVTGRLLTG-DCQKNIHLWTPTDGGSWHVDQRPFVGHTRS 263
+P+ +F GH E A+ W P +G LL + +W+ H Q H +
Sbjct: 403 RPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWSMKQEVCIHDLQ----AHNKE 456
Query: 264 VEDLQWSPT--------ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVIS 315
+ ++WSPT N + AS S D+++R+WDI + T T H V ++
Sbjct: 457 IYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWDI----ERGVCTHTLTKHQEPVYSVA 512
Query: 316 WSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGAD 375
+S +L SG D + IW+ +SG+ V +++ + V W+ + V AS +D
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNT---QSGNLVHSYR-GTGGIFEVCWNARGDKV-GASASD 567
Query: 376 HQITQWDL 383
+ DL
Sbjct: 568 GSVCVLDL 575
Score = 35.8 bits (81), Expect = 0.081
Identities = 23/96 (23%), Positives = 42/96 (43%), Gaps = 16/96 (16%)
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATF 349
++ SKA +L H+ +V + +W+ L SG D +IW+L + +G
Sbjct: 217 EVEIPSSKATVLR---GHESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLV 273
Query: 350 KQHV-----------APVTSVEWHPQDSGVFAASGA 374
+H VTS++W+ +G A+G+
Sbjct: 274 LRHCIREGGHDVPSNKDVTSLDWN--TNGTLLATGS 307
>gi|4758032 coatomer protein complex, subunit beta 2 (beta prime)
[Homo sapiens]
Length = 906
Score = 63.5 bits (153), Expect = 4e-10
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 12/137 (8%)
Query: 230 LLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIW 289
+LT I LW W Q F GHT V + +P +N FAS S D +I++W
Sbjct: 114 ILTSSDDMLIKLWDWDK--KWSCSQ-VFEGHTHYVMQIVINPKDNNQFASASLDRTIKVW 170
Query: 290 DIRAAPSKACMLTTATAHDGDVNVISW--SRREPFLLSGGDDGALKIWDLRQFKSGSPVA 347
+ ++ T H+ VN I + +P+L+SG DD +KIWD +++ + V
Sbjct: 171 QLGSSSPN----FTLEGHEKGVNCIDYYSGGDKPYLISGADDRLVKIWD---YQNKTCVQ 223
Query: 348 TFKQHVAPVTSVEWHPQ 364
T + H V+ +HP+
Sbjct: 224 TLEGHAQNVSCASFHPE 240
Score = 45.1 bits (105), Expect = 1e-04
Identities = 25/78 (32%), Positives = 40/78 (51%), Gaps = 2/78 (2%)
Query: 306 AHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQD 365
AH + I+ +PF+L+ DD +K+WD + S S V F+ H V + +P+D
Sbjct: 97 AHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKWSCSQV--FEGHTHYVMQIVINPKD 154
Query: 366 SGVFAASGADHQITQWDL 383
+ FA++ D I W L
Sbjct: 155 NNQFASASLDRTIKVWQL 172
Score = 33.1 bits (74), Expect = 0.52
Identities = 32/127 (25%), Positives = 55/127 (43%), Gaps = 7/127 (5%)
Query: 257 FVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISW 316
F H+ + + PT+ + S S D I++WD S + + T + + VI+
Sbjct: 95 FEAHSDYIRCIAVHPTQPFILTS-SDDMLIKLWDWDKKWSCSQVFEGHTHYVMQI-VINP 152
Query: 317 SRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADH 376
F S D +K+W Q S SP T + H V ++++ + SGAD
Sbjct: 153 KDNNQFA-SASLDRTIKVW---QLGSSSPNFTLEGHEKGVNCIDYYSGGDKPYLISGADD 208
Query: 377 QITQ-WD 382
++ + WD
Sbjct: 209 RLVKIWD 215
>gi|217330644 WD repeat domain 12 protein [Homo sapiens]
Length = 423
Score = 63.2 bits (152), Expect = 5e-10
Identities = 59/240 (24%), Positives = 100/240 (41%), Gaps = 27/240 (11%)
Query: 148 HYGGINRVRVSWLGEEPVAGVWSEKGQVEVFALRRLLQVVEEPQALAAFLRDEQAQMK-- 205
H G ++ + V G + +G W + + + + EE + + R + Q
Sbjct: 188 HAGSVDSIAVDGSGTKFCSGSWDK-----MLKIWSTVPTDEEDEMEESTNRPRKKQKTEQ 242
Query: 206 ------PIFSFAGHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVG 259
PI + +GHM ++ WS + + I +W G + +
Sbjct: 243 LGLTRTPIVTLSGHMEAVSSVLWSD--AEEICSASWDHTIRVWDVESGSL-----KSTLT 295
Query: 260 HTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWS-R 318
+ + +SP + AS S D IR+WD R L+ T+H G V + WS
Sbjct: 296 GNKVFNCISYSPLCKRL-ASGSTDRHIRLWDPRTKDGSLVSLSL-TSHTGWVTSVKWSPT 353
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQI 378
E L+SG D +K+WD R K +P+ H V SV+W D+G+ + GAD+++
Sbjct: 354 HEQQLISGSLDNIVKLWDTRSCK--APLYDLAAHEDKVLSVDW--TDTGLLLSGGADNKL 409
Score = 58.9 bits (141), Expect = 9e-09
Identities = 55/208 (26%), Positives = 86/208 (41%), Gaps = 36/208 (17%)
Query: 200 EQAQMKPIFSFAGHMG--EGFALDWSPRVTGRLLTGDCQKNIHLWT--PTDGGS------ 249
E+ ++K + GH G + A+D S + +G K + +W+ PTD
Sbjct: 175 ERNKVKALHCCRGHAGSVDSIAVDGSGT---KFCSGSWDKMLKIWSTVPTDEEDEMEEST 231
Query: 250 -----------WHVDQRPFV---GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAP 295
+ + P V GH +V + WS E S S D +IR+WD+ +
Sbjct: 232 NRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLWSDAEE--ICSASWDHTIRVWDVESGS 289
Query: 296 SKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVA-TFKQHVA 354
K+ + N IS+S L SG D +++WD R K GS V+ + H
Sbjct: 290 LKSTLTGNKV-----FNCISYSPLCKRLASGSTDRHIRLWDPRT-KDGSLVSLSLTSHTG 343
Query: 355 PVTSVEWHPQDSGVFAASGADHQITQWD 382
VTSV+W P + D+ + WD
Sbjct: 344 WVTSVKWSPTHEQQLISGSLDNIVKLWD 371
Score = 54.3 bits (129), Expect = 2e-07
Identities = 50/191 (26%), Positives = 75/191 (39%), Gaps = 35/191 (18%)
Query: 221 DWSPRVTGR---LLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPTENT-- 275
DW + G +LTG K +W+ +G S VGHT V+D+ W ++
Sbjct: 102 DWISSIKGAEEWILTGSYDKTSRIWS-LEGKSIMT----IVGHTDVVKDVAWVKKDSLSC 156
Query: 276 VFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIW 335
+ S S D +I +W+ +K L H G V+ I+ SG D LKIW
Sbjct: 157 LLLSASMDQTILLWEWNVERNKVKALHCCRGHAGSVDSIAVDGSGTKFCSGSWDKMLKIW 216
Query: 336 DL--------------RQFK---------SGSPVATFKQHVAPVTSVEWHPQDSGVFAAS 372
R K + +P+ T H+ V+SV W D+ ++
Sbjct: 217 STVPTDEEDEMEESTNRPRKKQKTEQLGLTRTPIVTLSGHMEAVSSVLW--SDAEEICSA 274
Query: 373 GADHQITQWDL 383
DH I WD+
Sbjct: 275 SWDHTIRVWDV 285
Score = 54.3 bits (129), Expect = 2e-07
Identities = 56/217 (25%), Positives = 95/217 (43%), Gaps = 29/217 (13%)
Query: 118 PSEGSDEEEEEEDEEDEEERKPQLELAMVPHYGGINRVRVSWLGEEPVAGVWSEKGQVEV 177
P++ DE EE + ++++ QL L P V +S E + +WS+ ++
Sbjct: 220 PTDEEDEMEESTNRPRKKQKTEQLGLTRTPI------VTLSGHMEAVSSVLWSDAEEICS 273
Query: 178 FALRRLLQVVE-EPQALAAFLRDEQAQMKPIFSFAGHMGEGFALDWSPRVTGRLLTGDCQ 236
+ ++V + E +L + L + +F+ + +SP + RL +G
Sbjct: 274 ASWDHTIRVWDVESGSLKSTLTGNK-----VFN---------CISYSP-LCKRLASGSTD 318
Query: 237 KNIHLWTP-TDGGSWHVDQRPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAP 295
++I LW P T GS + HT V ++WSPT S S D +++WD R+
Sbjct: 319 RHIRLWDPRTKDGS--LVSLSLTSHTGWVTSVKWSPTHEQQLISGSLDNIVKLWDTRSCK 376
Query: 296 SKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGAL 332
+ L AH+ V + W+ LLSGG D L
Sbjct: 377 AP---LYDLAAHEDKVLSVDWT-DTGLLLSGGADNKL 409
>gi|21071067 TBP-associated factor 5 [Homo sapiens]
Length = 800
Score = 62.8 bits (151), Expect = 6e-10
Identities = 43/152 (28%), Positives = 70/152 (46%), Gaps = 10/152 (6%)
Query: 255 RPFVGHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVI 314
R F GH V ++ P N V A+ SAD ++R+WD+ + T H G ++ +
Sbjct: 621 RIFAGHLADVNCTRFHPNSNYV-ATGSADRTVRLWDVL----NGNCVRIFTGHKGPIHSL 675
Query: 315 SWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGA 374
++S FL +G DG + +WD+ G V K H V S+ + +D + A+
Sbjct: 676 TFSPNGRFLATGATDGRVLLWDIGH---GLMVGELKGHTDTVCSLRF-SRDGEILASGSM 731
Query: 375 DHQITQWD-LAVERDPEAGDVEADPGLADLPQ 405
D+ + WD + D E D G +LP+
Sbjct: 732 DNTVRLWDAIKAFEDLETDDFTTATGHINLPE 763
Score = 49.3 bits (116), Expect = 7e-06
Identities = 33/125 (26%), Positives = 56/125 (44%), Gaps = 9/125 (7%)
Query: 259 GHTRSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSR 318
GH+ V +SP N + +S S D ++R+W ++ L H+ V +S
Sbjct: 541 GHSGPVYGASFSPDRNYLLSS-SEDGTVRLWSLQTFTC----LVGYKGHNYPVWDTQFSP 595
Query: 319 REPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQI 378
+ +SGG D ++W ++ P+ F H+A V +HP +S A AD +
Sbjct: 596 YGYYFVSGGHDRVARLWATDHYQ---PLRIFAGHLADVNCTRFHP-NSNYVATGSADRTV 651
Query: 379 TQWDL 383
WD+
Sbjct: 652 RLWDV 656
Score = 38.1 bits (87), Expect = 0.016
Identities = 28/100 (28%), Positives = 45/100 (45%), Gaps = 9/100 (9%)
Query: 281 SADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGALKIWDLRQF 340
S D RI D + A L H G V S+S +LLS +DG +++W L+ F
Sbjct: 520 SDDVLERIMDEKTASE----LKILYGHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTF 575
Query: 341 KSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQ 380
+ + +K H PV ++ P G + SG ++ +
Sbjct: 576 ---TCLVGYKGHNYPVWDTQFSPY--GYYFVSGGHDRVAR 610
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 62.8 bits (151), Expect = 6e-10
Identities = 46/179 (25%), Positives = 74/179 (41%), Gaps = 22/179 (12%)
Query: 213 HMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPFVGHTRSVEDLQWSPT 272
H G FAL W+ + +L+ K +W G + ++ F H+ D+ W
Sbjct: 265 HKGPIFALKWNKK-GNFILSAGVDKTTIIWDAHTGEA----KQQFPFHSAPALDVDWQ-- 317
Query: 273 ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREPFLLSGGDDGAL 332
N FASCS D I + + + + T H +VN I W L S DD L
Sbjct: 318 SNNTFASCSTDMCIHVCKL----GQDRPIKTFQGHTNEVNAIKWDPTGNLLASCSDDMTL 373
Query: 333 KIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSG--------VFAASGADHQITQWDL 383
KIW ++Q + V + H + +++W P G + A++ D + WD+
Sbjct: 374 KIWSMKQ---DNCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV 429
Score = 62.8 bits (151), Expect = 6e-10
Identities = 51/190 (26%), Positives = 85/190 (44%), Gaps = 24/190 (12%)
Query: 203 QMKPIFSFAGHMGEGFALDWSPRVTGRLLTG-DCQKNIHLWTPTDGGSWHVDQRPFVGHT 261
Q +PI +F GH E A+ W P TG LL + +W+ H Q H
Sbjct: 338 QDRPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIWSMKQDNCVHDLQ----AHN 391
Query: 262 RSVEDLQWSPT--------ENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNV 313
+ + ++WSPT N + AS S D+++R+WD+ + + T T H V
Sbjct: 392 KEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWDV----DRGICIHTLTKHQEPVYS 447
Query: 314 ISWSRREPFLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASG 373
+++S +L SG D + IW+ ++G+ V +++ + V W+ V AS
Sbjct: 448 VAFSPDGRYLASGSFDKCVHIWNT---QTGALVHSYR-GTGGIFEVCWNAAGDKV-GASA 502
Query: 374 ADHQITQWDL 383
+D + DL
Sbjct: 503 SDGSVCVLDL 512
Score = 60.8 bits (146), Expect = 2e-09
Identities = 49/186 (26%), Positives = 74/186 (39%), Gaps = 22/186 (11%)
Query: 212 GHMGEGFALDWSPRVTGRLLTGDCQKNIHLWTPTDGGSWHVDQRPF----------VGHT 261
GH E F W+P V+ L +G +W ++ + Q V
Sbjct: 167 GHESEVFICAWNP-VSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSN 225
Query: 262 RSVEDLQWSPTENTVFASCSADASIRIWDIRAAPSKACMLTTATAHDGDVNVISWSRREP 321
+ V L W+ +E T+ A+ S D RIW + +T H G + + W+++
Sbjct: 226 KDVTSLDWN-SEGTLLATGSYDGFARIWT-----KDGNLASTLGQHKGPIFALKWNKKGN 279
Query: 322 FLLSGGDDGALKIWDLRQFKSGSPVATFKQHVAPVTSVEWHPQDSGVFAASGADHQITQW 381
F+LS G D IWD +G F H AP V+W Q + FA+ D I
Sbjct: 280 FILSAGVDKTTIIWDAH---TGEAKQQFPFHSAPALDVDW--QSNNTFASCSTDMCIHVC 334
Query: 382 DLAVER 387
L +R
Sbjct: 335 KLGQDR 340
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,014,599
Number of Sequences: 37866
Number of extensions: 1016453
Number of successful extensions: 17849
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 466
Number of HSP's successfully gapped in prelim test: 194
Number of HSP's that attempted gapping in prelim test: 10513
Number of HSP's gapped (non-prelim): 4729
length of query: 446
length of database: 18,247,518
effective HSP length: 105
effective length of query: 341
effective length of database: 14,271,588
effective search space: 4866611508
effective search space used: 4866611508
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.