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Search of human proteins with 23110939
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]
(248 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens] 495 e-140
gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens] 488 e-138
gi|23110942 proteasome alpha 5 subunit [Homo sapiens] 122 3e-28
gi|4506189 proteasome alpha 7 subunit [Homo sapiens] 119 3e-27
gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens] 117 7e-27
gi|23110944 proteasome alpha 6 subunit [Homo sapiens] 111 5e-25
gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens] 111 7e-25
gi|4506181 proteasome subunit alpha type 2 [Homo sapiens] 110 1e-24
gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 105 3e-23
gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens] 105 3e-23
gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens] 91 7e-19
gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens] 91 7e-19
gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens] 77 2e-14
gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens] 77 2e-14
gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09
gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09
gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens] 60 2e-09
gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens] 58 9e-09
gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens] 33 0.23
gi|117553586 dedicator of cytokinesis 5 [Homo sapiens] 33 0.30
gi|212276078 leucine rich repeat (in FLII) interacting protein 1... 30 1.5
gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens] 30 2.0
gi|14670383 death-associated kinase 2 [Homo sapiens] 28 5.7
gi|55749742 HEAT repeat containing 5B [Homo sapiens] 28 5.7
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 28 5.7
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 28 5.7
gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens] 28 7.4
gi|153945728 microtubule-associated protein 1B [Homo sapiens] 28 7.4
gi|134152708 arginine and glutamate rich 1 [Homo sapiens] 28 7.4
gi|145309326 laminin, gamma 1 precursor [Homo sapiens] 28 9.7
>gi|23110939 proteasome alpha 3 subunit isoform 2 [Homo sapiens]
Length = 248
Score = 495 bits (1274), Expect = e-140
Identities = 248/248 (100%), Positives = 248/248 (100%)
Query: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60
MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE
Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60
Query: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV
Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
Query: 121 HAYTLYSAVRPFGCSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
HAYTLYSAVRPFGCSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC
Sbjct: 121 HAYTLYSAVRPFGCSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
Query: 181 RDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEE 240
RDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEE
Sbjct: 181 RDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEE 240
Query: 241 DESDDDNM 248
DESDDDNM
Sbjct: 241 DESDDDNM 248
>gi|4506183 proteasome alpha 3 subunit isoform 1 [Homo sapiens]
Length = 255
Score = 488 bits (1256), Expect = e-138
Identities = 248/255 (97%), Positives = 248/255 (97%), Gaps = 7/255 (2%)
Query: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60
MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE
Sbjct: 1 MSSIGTGYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYE 60
Query: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV
Sbjct: 61 EGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYV 120
Query: 121 HAYTLYSAVRPFGC-------SVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 173
HAYTLYSAVRPFGC SVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL
Sbjct: 121 HAYTLYSAVRPFGCSFMLGSYSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKL 180
Query: 174 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 233
QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA
Sbjct: 181 QMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 240
Query: 234 KESLKEEDESDDDNM 248
KESLKEEDESDDDNM
Sbjct: 241 KESLKEEDESDDDNM 255
>gi|23110942 proteasome alpha 5 subunit [Homo sapiens]
Length = 241
Score = 122 bits (306), Expect = 3e-28
Identities = 75/214 (35%), Positives = 120/214 (56%), Gaps = 12/214 (5%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD +TFSP+GR+FQVEYA++A++ STAIGI+ +GV VEK + S L E S +++
Sbjct: 8 YDRGVNTFSPEGRLFQVEYAIEAIKLGSTAIGIQTSEGVCLAVEKRITSPLMEPSSIEKI 67
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
+D H+G A++GL+ADA++L D AR E N + + ++ + V+ +
Sbjct: 68 VEIDAHIGCAMSGLIADAKTLIDKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEED 127
Query: 128 A-----VRPFGCSV------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK 176
A RPFG ++ G QL+ +DPSG AIG A + A++ ++++ K
Sbjct: 128 ADPGAMSRPFGVALLFGGVDEKGPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHK 187
Query: 177 EMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWV 210
MT ++ +K I+ V +E K A +EL+ V
Sbjct: 188 SMTLKEAIKSSLIILKQVMEE-KLNATNIELATV 220
>gi|4506189 proteasome alpha 7 subunit [Homo sapiens]
Length = 248
Score = 119 bits (297), Expect = 3e-27
Identities = 81/250 (32%), Positives = 135/250 (54%), Gaps = 25/250 (10%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + + FSPDG +FQVEYA +AV+ STA+G+R +D VV GVEK ++KL +E + +++
Sbjct: 3 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGVRGRDIVVLGVEKKSVAKLQDERTVRKI 62
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
+D +V MA AGL ADAR + + AR E + R + ++++ +A YT +
Sbjct: 63 CALDDNVCMAFAGLTADARIVINRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSN 122
Query: 128 AVRPFGCSV------NDGA-QLYMIDPSGVSYGYWGCAIGKARQAAKTEIEK------LQ 174
RPFG S DG +LY DPSG + + AIG+ ++ + +EK ++
Sbjct: 123 GRRPFGISALIVGFDFDGTPRLYQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIE 182
Query: 175 MKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAK 234
++T + ++K + +++ + K EL + R + + EE EKY
Sbjct: 183 TDDLTIKLVIKALLEVV-----QSGGKNIELAVM-------RRDQSLKILNPEEIEKYVA 230
Query: 235 ESLKEEDESD 244
E KE++E++
Sbjct: 231 EIEKEKEENE 240
>gi|68303563 proteasome alpha 8 subunit isoform 2 [Homo sapiens]
Length = 250
Score = 117 bits (294), Expect = 7e-27
Identities = 81/245 (33%), Positives = 134/245 (54%), Gaps = 15/245 (6%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + + FSPDG +FQVEYA +AV+ STA+GIR + VV GVEK ++KL +E + +++
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
+D HV MA AGL ADAR + + AR E + + + ++++ +A YT +
Sbjct: 65 CALDDHVCMAFAGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 124
Query: 128 AVRPFGCSV------NDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
RPFG S +DG ++LY DPSG + + AIG++ + + +EK ++
Sbjct: 125 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 184
Query: 181 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 239
D E K+ I + + V+ +EL+ + R++ + +E E Y E KE
Sbjct: 185 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 237
Query: 240 EDESD 244
++E++
Sbjct: 238 KEEAE 242
>gi|23110944 proteasome alpha 6 subunit [Homo sapiens]
Length = 246
Score = 111 bits (278), Expect = 5e-25
Identities = 61/179 (34%), Positives = 96/179 (53%), Gaps = 8/179 (4%)
Query: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSS-TAIGIRCKDGVVFGVEKLVLSKLYEEGSNK 65
G+D + FSP+GR++QVEYA KA+ T++ +R KD V +K V KL + +
Sbjct: 8 GFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVT 67
Query: 66 RLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTL 125
LF + ++G + G+ AD+RS AR EA+N++ +GY IP+ L R+A YT
Sbjct: 68 HLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQ 127
Query: 126 YSAVRPFGCSV-------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKE 177
+ +RP GC + G Q+Y DP+G G+ A G + + + +EK K+
Sbjct: 128 NAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKK 186
>gi|68303561 proteasome alpha 8 subunit isoform 1 [Homo sapiens]
Length = 256
Score = 111 bits (277), Expect = 7e-25
Identities = 81/251 (32%), Positives = 134/251 (53%), Gaps = 21/251 (8%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + + FSPDG +FQVEYA +AV+ STA+GIR + VV GVEK ++KL +E + +++
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIRGTNIVVLGVEKKSVAKLQDERTVRKI 64
Query: 68 FNVDRHVGMAVA------GLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVH 121
+D HV MA A GL ADAR + + AR E + + + ++++ +A
Sbjct: 65 CALDDHVCMAFAVLTIFIGLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQ 124
Query: 122 AYTLYSAVRPFGCSV------NDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQ 174
YT + RPFG S +DG ++LY DPSG + + AIG++ + + +EK
Sbjct: 125 KYTQSNGRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNY 184
Query: 175 MKEMTCRDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYA 233
++ D E K+ I + + V+ +EL+ + R++ + +E E Y
Sbjct: 185 TEDAIASD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYV 237
Query: 234 KESLKEEDESD 244
E KE++E++
Sbjct: 238 TEIEKEKEEAE 248
>gi|4506181 proteasome subunit alpha type 2 [Homo sapiens]
Length = 234
Score = 110 bits (275), Expect = 1e-24
Identities = 64/184 (34%), Positives = 97/184 (52%), Gaps = 6/184 (3%)
Query: 7 GYDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKR 66
GY S +TFSP G++ Q+EYA+ AV + ++GI+ +GVV EK S LY+E S +
Sbjct: 5 GYSFSLTTFSPSGKLVQIEYALAAVAGGAPSVGIKAANGVVLATEKKQKSILYDERSVHK 64
Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
+ + +H+G+ +G+ D R L AR+ A + + IP L RVA + YT
Sbjct: 65 VEPITKHIGLVYSGMGPDYRVLVHRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQS 124
Query: 127 SAVRPFG-----CSVNDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
VRPFG C N+G L+ DPSG + + A+GK KT +EK +++
Sbjct: 125 GGVRPFGVSLLICGWNEGRPYLFQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLEL 184
Query: 181 RDIV 184
D +
Sbjct: 185 EDAI 188
>gi|156713442 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 105 bits (263), Expect = 3e-23
Identities = 76/258 (29%), Positives = 127/258 (49%), Gaps = 23/258 (8%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66
YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
++ ++ + +VAG+ +DA L + R A + + IP + L + AYT +
Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 127 SAVRPFGCSV-------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 177
RPFG S+ + G QLY DPSG +YG W AA + K K E
Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
Query: 178 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 226
MT + + K++ D K A ++E++ + NG+ +++ K
Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242
Query: 227 EEAEKYAKESLKEEDESD 244
EEA+ ++ KE+ E D
Sbjct: 243 EEAKAEREKKEKEQKEKD 260
>gi|4506185 proteasome alpha 4 subunit isoform 1 [Homo sapiens]
Length = 261
Score = 105 bits (263), Expect = 3e-23
Identities = 76/258 (29%), Positives = 127/258 (49%), Gaps = 23/258 (8%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEE-GSNKR 66
YD + FSP+GR++QVEYAM+A+ ++ T +GI DGV+ E+ + KL +E +++
Sbjct: 5 YDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEK 64
Query: 67 LFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLY 126
++ ++ + +VAG+ +DA L + R A + + IP + L + AYT +
Sbjct: 65 IYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQF 124
Query: 127 SAVRPFGCSV-------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--E 177
RPFG S+ + G QLY DPSG +YG W AA + K K E
Sbjct: 125 GGKRPFGVSLLYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGE 183
Query: 178 MTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIR 226
MT + + K++ D K A ++E++ + NG+ +++ K
Sbjct: 184 MTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEE 242
Query: 227 EEAEKYAKESLKEEDESD 244
EEA+ ++ KE+ E D
Sbjct: 243 EEAKAEREKKEKEQKEKD 260
>gi|4506179 proteasome alpha 1 subunit isoform 2 [Homo sapiens]
Length = 263
Score = 91.3 bits (225), Expect = 7e-19
Identities = 54/179 (30%), Positives = 89/179 (49%), Gaps = 8/179 (4%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++
Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 63
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
+VD H+G+++AGL ADAR L + R+E + R F +P+ L + T
Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 123
Query: 128 AVRPFGCSV------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
RP+G + + G ++ PS + +IG Q+A+T +E+ + M C
Sbjct: 124 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 182
>gi|23110935 proteasome alpha 1 subunit isoform 1 [Homo sapiens]
Length = 269
Score = 91.3 bits (225), Expect = 7e-19
Identities = 54/179 (30%), Positives = 89/179 (49%), Gaps = 8/179 (4%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++
Sbjct: 12 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 69
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
+VD H+G+++AGL ADAR L + R+E + R F +P+ L + T
Sbjct: 70 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRY 129
Query: 128 AVRPFGCSV------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
RP+G + + G ++ PS + +IG Q+A+T +E+ + M C
Sbjct: 130 GRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMEC 188
>gi|68303565 proteasome alpha 8 subunit isoform 3 [Homo sapiens]
Length = 212
Score = 76.6 bits (187), Expect = 2e-14
Identities = 66/245 (26%), Positives = 110/245 (44%), Gaps = 53/245 (21%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + + FSPDG +FQVEYA +AV+ STA+GIR
Sbjct: 5 YDRAITVFSPDGHLFQVEYAQEAVKKGSTAVGIR-------------------------- 38
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYS 127
GL ADAR + + AR E + + + ++++ +A YT +
Sbjct: 39 ------------GLTADARVVINRARVECQSHKLTVEDPVTVEYITRFIATLKQKYTQSN 86
Query: 128 AVRPFGCSV------NDG-AQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTC 180
RPFG S +DG ++LY DPSG + + AIG++ + + +EK ++
Sbjct: 87 GRRPFGISALIVGFDDDGISRLYQTDPSGTYHAWKANAIGRSAKTVREFLEKNYTEDAIA 146
Query: 181 RDIVKEVAKI-IYIVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKE 239
D E K+ I + + V+ +EL+ + R++ + +E E Y E KE
Sbjct: 147 SD--SEAIKLAIKALLEVVQSGGKNIELAII-----RRNQPLKMFSAKEVELYVTEIEKE 199
Query: 240 EDESD 244
++E++
Sbjct: 200 KEEAE 204
>gi|221316716 proteasome alpha 1 subunit isoform 3 [Homo sapiens]
Length = 130
Score = 76.6 bits (187), Expect = 2e-14
Identities = 39/109 (35%), Positives = 62/109 (56%), Gaps = 2/109 (1%)
Query: 8 YDLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRL 67
YD + +SP GR+ Q+EYAM+AV+ S +G++ K V K S+L K++
Sbjct: 6 YDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSEL--AAHQKKI 63
Query: 68 FNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRV 116
+VD H+G+++AGL ADAR L + R+E + R F +P+ L +
Sbjct: 64 LHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLI 112
>gi|169206322 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 60.1 bits (144), Expect = 2e-09
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64
TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S
Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148
Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102
LF + ++ G + G+ AD+RS A+ +A+N + N
Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186
>gi|239750562 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 60.1 bits (144), Expect = 2e-09
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64
TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S
Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148
Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102
LF + ++ G + G+ AD+RS A+ +A+N + N
Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186
>gi|239744861 PREDICTED: similar to hCG30646 [Homo sapiens]
Length = 272
Score = 60.1 bits (144), Expect = 2e-09
Identities = 34/98 (34%), Positives = 56/98 (57%), Gaps = 3/98 (3%)
Query: 6 TGYDLSASTFSPDGRVFQVEYAMKAV-ENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN 64
TG+D FSP +++QV+YA KA+ + T++ +R KD V K+V KL + S
Sbjct: 91 TGFDRHLIIFSPKVQLYQVQYAFKAINQGGLTSVAVRKKDCAVIVTHKIVPDKLLD--SR 148
Query: 65 KRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSN 102
LF + ++ G + G+ AD+RS A+ +A+N + N
Sbjct: 149 THLFKMTKNTGRVITGVTADSRSREQRAQYKAANCKYN 186
>gi|156713444 proteasome alpha 4 subunit isoform 2 [Homo sapiens]
Length = 190
Score = 57.8 bits (138), Expect = 9e-09
Identities = 52/188 (27%), Positives = 82/188 (43%), Gaps = 22/188 (11%)
Query: 77 AVAGLLADARSLADIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSV 136
+VAG+ +DA L + R A + + IP + L + AYT + RPFG S+
Sbjct: 4 SVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSL 63
Query: 137 -------NDGAQLYMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMK--EMTCRDIVKEV 187
+ G QLY DPSG +YG W AA + K K EMT + +
Sbjct: 64 LYIGWDKHYGFQLYQSDPSG-NYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALA 122
Query: 188 AKIIYIVHDEVKDKAFELELSWVGELTNGR-----------HEIVPKDIREEAEKYAKES 236
K++ D K A ++E++ + NG+ +++ K EEA+ ++
Sbjct: 123 IKVLNKTMDVSKLSAEKVEIATLTR-ENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREKK 181
Query: 237 LKEEDESD 244
KE+ E D
Sbjct: 182 EKEQKEKD 189
>gi|4504211 guanylate cyclase 1, soluble, alpha 2 [Homo sapiens]
Length = 732
Score = 33.1 bits (74), Expect = 0.23
Identities = 18/62 (29%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Query: 9 DLSASTFSPDGRVFQVEYAMKAVENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLF 68
+LS +PDGR Q+ + + + +G+R +FG + L+ +E GS+ R
Sbjct: 598 ELSEEVLTPDGRPIQMRIGIHSGSVLAGVVGVRMPRYCLFG-NNVTLASKFESGSHPRRI 656
Query: 69 NV 70
NV
Sbjct: 657 NV 658
>gi|117553586 dedicator of cytokinesis 5 [Homo sapiens]
Length = 1870
Score = 32.7 bits (73), Expect = 0.30
Identities = 24/92 (26%), Positives = 40/92 (43%), Gaps = 11/92 (11%)
Query: 120 VHAYTLYSAVRPFGCSVNDGAQLYM--IDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKE 177
+H Y LY + F C++ + A+L+M DP ++ I EIEKL +
Sbjct: 219 IHTYGLYVNFKNFVCNIGEDAELFMALYDPDQSTFISENYLIRWGSNGMPKEIEKLNNLQ 278
Query: 178 MTCRDI---------VKEVAKIIYIVHDEVKD 200
D+ V V +I+ + H E+K+
Sbjct: 279 AVFTDLSSMDLIRPRVSLVCQIVRVGHMELKE 310
>gi|212276078 leucine rich repeat (in FLII) interacting protein 1
isoform 1 [Homo sapiens]
Length = 640
Score = 30.4 bits (67), Expect = 1.5
Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 20/85 (23%)
Query: 162 ARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIV 221
A++AA+ E +++MKE+ + K IY +V+ K + L+ W G++
Sbjct: 39 AKRAARAEAREIRMKEL------ERQQKEIY----QVQKKYYGLDTKW-GDI-------- 79
Query: 222 PKDIREEAEKYAKESLKEEDESDDD 246
+ E++E+Y++ S + SD+D
Sbjct: 80 -EQWMEDSERYSRRSRRNTSASDED 103
>gi|22035677 AT rich interactive domain 4B isoform 1 [Homo sapiens]
Length = 1312
Score = 30.0 bits (66), Expect = 2.0
Identities = 13/21 (61%), Positives = 16/21 (76%)
Query: 227 EEAEKYAKESLKEEDESDDDN 247
EEAE+ +E +EEDE DDDN
Sbjct: 540 EEAEEEEEEEEEEEDEDDDDN 560
>gi|14670383 death-associated kinase 2 [Homo sapiens]
Length = 370
Score = 28.5 bits (62), Expect = 5.7
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 3/82 (3%)
Query: 108 PLKHLADRVAMYVHAYTLYSAVRPFGCSVNDGAQLYMIDPSGVSYGYWGCAIGKARQAAK 167
PL AD ++ V Y L S PF + D Q + + + VSY + + + AK
Sbjct: 203 PLGLEADMWSIGVITYILLSGASPF---LGDTKQETLANITAVSYDFDEEFFSQTSELAK 259
Query: 168 TEIEKLQMKEMTCRDIVKEVAK 189
I KL +KE R ++E +
Sbjct: 260 DFIRKLLVKETRKRLTIQEALR 281
>gi|55749742 HEAT repeat containing 5B [Homo sapiens]
Length = 2071
Score = 28.5 bits (62), Expect = 5.7
Identities = 11/27 (40%), Positives = 18/27 (66%)
Query: 220 IVPKDIREEAEKYAKESLKEEDESDDD 246
+V +I++EAE K ++K D+ DDD
Sbjct: 1431 VVAMNIKKEAESKPKRAIKNTDDDDDD 1457
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 28.5 bits (62), Expect = 5.7
Identities = 11/25 (44%), Positives = 18/25 (72%)
Query: 223 KDIREEAEKYAKESLKEEDESDDDN 247
K ++++ EK AK K+EDE D+D+
Sbjct: 101 KKLKDKKEKKAKRKKKDEDEDDNDD 125
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 28.5 bits (62), Expect = 5.7
Identities = 20/80 (25%), Positives = 38/80 (47%), Gaps = 13/80 (16%)
Query: 163 RQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEIVP 222
+++ K E+E++Q + T R + V I + +K ++F +E
Sbjct: 623 QKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKL------------- 669
Query: 223 KDIREEAEKYAKESLKEEDE 242
KD+ E EK+ +E L+E+ E
Sbjct: 670 KDLLAEKEKFEEERLREQQE 689
>gi|24234688 heat shock 70kDa protein 9 precursor [Homo sapiens]
Length = 679
Score = 28.1 bits (61), Expect = 7.4
Identities = 17/56 (30%), Positives = 30/56 (53%)
Query: 193 IVHDEVKDKAFELELSWVGELTNGRHEIVPKDIREEAEKYAKESLKEEDESDDDNM 248
IVH KDK E V + + G + +++ + AEKYA+E ++++ + NM
Sbjct: 529 IVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAEKYAEEDRRKKERVEAVNM 584
>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
Length = 2468
Score = 28.1 bits (61), Expect = 7.4
Identities = 21/83 (25%), Positives = 43/83 (51%), Gaps = 19/83 (22%)
Query: 162 ARQAAKTEIEKLQM--KEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHE 219
A++ KT I+K + KE +++ KE+ K +E K+ E+ + E
Sbjct: 661 AKKEDKTPIKKEEKPKKEEVKKEVKKEIKK------EEKKEPKKEV-----------KKE 703
Query: 220 IVPKDIREEAEKYAKESLKEEDE 242
PK++++E +K K+ +K+E++
Sbjct: 704 TPPKEVKKEVKKEEKKEVKKEEK 726
>gi|134152708 arginine and glutamate rich 1 [Homo sapiens]
Length = 273
Score = 28.1 bits (61), Expect = 7.4
Identities = 23/87 (26%), Positives = 45/87 (51%), Gaps = 9/87 (10%)
Query: 161 KARQAAKTEIEKLQMKEMTCRDIVKEVAKIIYIVHDEVKDKAFELELSWVGELTNGRHEI 220
+ R+ + EIE+ ++E T R + + VAK V +E++ + E+E + + + I
Sbjct: 112 RQRKIRQQEIEEKLIEEETARRVEELVAK---RVEEELEKRKDEIEREVLRRVEEAK-RI 167
Query: 221 VPKDIREEAEK-----YAKESLKEEDE 242
+ K + EE E+ A + +EE+E
Sbjct: 168 MEKQLLEELERQRQAELAAQKAREEEE 194
>gi|145309326 laminin, gamma 1 precursor [Homo sapiens]
Length = 1609
Score = 27.7 bits (60), Expect = 9.7
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 8/86 (9%)
Query: 169 EIEKLQMKEMTCRDIVKEVAKIIYIVHDEVK---DKAFEL--ELSWVGELTNGRHEIVPK 223
EIE+L K ++I +++ K VH+E K DKA E+ ++ + L + E
Sbjct: 1228 EIEELNRKYEQAKNISQDLEKQAARVHEEAKRAGDKAVEIYASVAQLSPLDSETLENEAN 1287
Query: 224 DIREEAEKYAK---ESLKEEDESDDD 246
+I+ EAE + + LK+ ++ +D
Sbjct: 1288 NIKMEAENLEQLIDQKLKDYEDLRED 1313
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.133 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,342,795
Number of Sequences: 37866
Number of extensions: 325331
Number of successful extensions: 1477
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1422
Number of HSP's gapped (non-prelim): 42
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.